SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 27.734 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 Gene3D G3DSA:3.30.70.990 10 94 5.3E-28 T 28-03-2018 IPR035570 UPF0234 N-terminal domain SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 SUPERFAMILY SSF89963 89 160 8.11E-26 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 Gene3D G3DSA:3.30.70.860 95 159 2.5E-29 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 3.3E-59 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SmaCSM2_RS18550 80cf6f7fe532beb1efa5b811ccb88649 160 SUPERFAMILY SSF89963 2 84 4.45E-28 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 25.348 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 PRINTS PR00297 10kDa chaperonin signature 3 18 1.1E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 PRINTS PR00297 10kDa chaperonin signature 25 46 1.1E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 PRINTS PR00297 10kDa chaperonin signature 60 72 1.1E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 PRINTS PR00297 10kDa chaperonin signature 81 94 1.1E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.2E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 SUPERFAMILY SSF50129 1 94 5.05E-32 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 SMART SM00883 2 94 2.0E-51 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS19225 bb2eaafee3bb167216f6edfa4711277f 95 Gene3D G3DSA:2.30.33.40 1 95 6.4E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SmaCSM2_RS11320 bf4e548b490e1a207fc83c1e75cda632 141 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 116 8.1E-14 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 SmaCSM2_RS11320 bf4e548b490e1a207fc83c1e75cda632 141 Gene3D G3DSA:3.90.1590.10 1 137 1.2E-17 T 28-03-2018 SmaCSM2_RS11320 bf4e548b490e1a207fc83c1e75cda632 141 SUPERFAMILY SSF51316 3 135 2.41E-24 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 Gene3D G3DSA:3.20.20.100 3 322 5.2E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 SUPERFAMILY SSF51430 1 321 1.83E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 276 289 1.3E-8 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 237 249 1.3E-8 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 263 275 1.3E-8 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 164 183 1.3E-8 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 113 123 1.3E-8 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 SmaCSM2_RS03430 abc3133b7635c524c89843afc99fa800 323 Pfam PF00248 Aldo/keto reductase family 16 313 3.7E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 3.4E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 SMART SM00862 145 220 1.9E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 Pfam PF00072 Response regulator receiver domain 3 113 3.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 SUPERFAMILY SSF52172 1 170 2.05E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 Gene3D G3DSA:1.10.10.10 116 227 3.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 SMART SM00448 1 112 5.0E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01315 8ea3485fb6ebceadebd003035503a023 227 Gene3D G3DSA:3.40.50.2300 1 115 7.3E-35 T 28-03-2018 SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 1.3E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 Gene3D G3DSA:3.40.50.2300 1 123 1.7E-33 T 28-03-2018 SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 SUPERFAMILY SSF52172 2 174 7.68E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 SMART SM00448 1 113 2.9E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 Gene3D G3DSA:1.10.10.10 124 225 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16965 75168cc00a6257e98007ca4dd04cb516 225 SMART SM00862 146 220 5.1E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 Pfam PF00227 Proteasome subunit 9 181 4.4E-22 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 PIRSF PIRSF039093 6 183 1.9E-82 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 Gene3D G3DSA:3.60.20.10 13 183 1.1E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 12 183 40.966 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 SUPERFAMILY SSF56235 9 182 2.04E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS18465 eb16c558575a6b2dc11933d7b2bdd1fc 183 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 13 183 4.5E-82 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 SMART SM00939 291 519 1.2E-10 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 415 501 2.1E-7 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 SUPERFAMILY SSF49785 359 522 1.53E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 Gene3D G3DSA:2.60.120.260 320 524 2.8E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 34 272 1.2E-27 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 Gene3D G3DSA:3.40.50.1820 17 319 9.2E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11470 47431062809d6196ee54d924eb50a71a 524 SUPERFAMILY SSF53474 23 314 9.87E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 SUPERFAMILY SSF52172 3 135 1.99E-20 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 Gene3D G3DSA:1.10.10.10 130 212 8.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 SMART SM00448 3 119 9.3E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 Gene3D G3DSA:3.40.50.2300 2 129 1.1E-18 T 28-03-2018 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 SMART SM00421 146 203 5.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 SUPERFAMILY SSF46894 142 207 7.82E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS14885 1a74a198c0db85a1ae2e3d8ddf4897af 223 Pfam PF00072 Response regulator receiver domain 5 113 1.8E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 SMART SM00448 182 303 1.2E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 Gene3D G3DSA:2.30.30.40 110 151 8.7E-11 T 28-03-2018 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 PIRSF PIRSF002867 2 311 9.6E-96 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 SUPERFAMILY SSF50341 18 160 1.2E-32 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 Pfam PF01584 CheW-like domain 23 159 1.4E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 Gene3D G3DSA:2.40.50.180 40 109 5.9E-14 T 28-03-2018 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 SUPERFAMILY SSF52172 178 309 5.83E-23 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 SMART SM00260 18 157 1.2E-23 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 Pfam PF00072 Response regulator receiver domain 184 299 1.4E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10305 8edf99e422b3015b933d46365af43cea 314 Gene3D G3DSA:3.40.50.2300 174 313 1.6E-21 T 28-03-2018 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 Pfam PF12833 Helix-turn-helix domain 197 275 1.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 SMART SM00342 191 274 7.1E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 Gene3D G3DSA:1.10.10.60 94 226 0.0059 T 28-03-2018 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 SUPERFAMILY SSF51215 34 156 3.14E-5 T 28-03-2018 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 Gene3D G3DSA:1.10.10.60 227 276 5.9E-10 T 28-03-2018 SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 Gene3D G3DSA:2.60.120.10 2 93 8.5E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS09405 09763f78bdea7dc0af87721c1f91a1b9 297 SUPERFAMILY SSF46689 233 275 2.33E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 Pfam PF08502 LeuA allosteric (dimerisation) domain 382 509 5.0E-27 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 SUPERFAMILY SSF110921 421 508 5.36E-19 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 Pfam PF00682 HMGL-like 11 284 2.5E-87 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 9 518 39.633 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 11 506 4.0E-189 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 211 224 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 Gene3D G3DSA:3.20.20.70 2 343 1.1E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 SMART SM00917 381 509 9.9E-28 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SmaCSM2_RS17760 0154c59c89185633c5512cd1aead2653 528 SUPERFAMILY SSF51569 6 303 3.66E-91 T 28-03-2018 SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 Gene3D G3DSA:3.40.190.10 176 264 2.4E-21 T 28-03-2018 SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 Gene3D G3DSA:3.40.190.10 89 175 3.2E-14 T 28-03-2018 SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 SUPERFAMILY SSF46785 4 112 6.02E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 SUPERFAMILY SSF53850 89 299 4.16E-41 T 28-03-2018 SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.6E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 Pfam PF03466 LysR substrate binding domain 89 295 2.0E-37 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS01135 24b32205f533231988edb8a705de8c67 303 Gene3D G3DSA:1.10.10.10 2 87 1.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 SUPERFAMILY SSF53335 22 249 1.06E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 18 252 38.033 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 Gene3D G3DSA:3.40.50.150 10 252 1.7E-44 T 28-03-2018 SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 160 174 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 38 53 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 27 252 1.2E-81 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SmaCSM2_RS18405 f2fbbba08c245e88ca635f5f077cd23a 253 Pfam PF01209 ubiE/COQ5 methyltransferase family 23 252 4.5E-90 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SmaCSM2_RS18790 4014093d4244f2062729de5e45e1c45c 286 Gene3D G3DSA:3.30.420.10 126 286 1.3E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS18790 4014093d4244f2062729de5e45e1c45c 286 SUPERFAMILY SSF53098 127 277 6.07E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS18790 4014093d4244f2062729de5e45e1c45c 286 Pfam PF00665 Integrase core domain 128 237 5.4E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS18790 4014093d4244f2062729de5e45e1c45c 286 Pfam PF13276 HTH-like domain 44 99 8.1E-14 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS02940 4014093d4244f2062729de5e45e1c45c 286 Gene3D G3DSA:3.30.420.10 126 286 1.3E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS02940 4014093d4244f2062729de5e45e1c45c 286 SUPERFAMILY SSF53098 127 277 6.07E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS02940 4014093d4244f2062729de5e45e1c45c 286 Pfam PF00665 Integrase core domain 128 237 5.4E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS02940 4014093d4244f2062729de5e45e1c45c 286 Pfam PF13276 HTH-like domain 44 99 8.1E-14 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS06840 4014093d4244f2062729de5e45e1c45c 286 Gene3D G3DSA:3.30.420.10 126 286 1.3E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06840 4014093d4244f2062729de5e45e1c45c 286 SUPERFAMILY SSF53098 127 277 6.07E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06840 4014093d4244f2062729de5e45e1c45c 286 Pfam PF00665 Integrase core domain 128 237 5.4E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS06840 4014093d4244f2062729de5e45e1c45c 286 Pfam PF13276 HTH-like domain 44 99 8.1E-14 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS19525 4014093d4244f2062729de5e45e1c45c 286 Gene3D G3DSA:3.30.420.10 126 286 1.3E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS19525 4014093d4244f2062729de5e45e1c45c 286 SUPERFAMILY SSF53098 127 277 6.07E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS19525 4014093d4244f2062729de5e45e1c45c 286 Pfam PF00665 Integrase core domain 128 237 5.4E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS19525 4014093d4244f2062729de5e45e1c45c 286 Pfam PF13276 HTH-like domain 44 99 8.1E-14 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS10005 4014093d4244f2062729de5e45e1c45c 286 Gene3D G3DSA:3.30.420.10 126 286 1.3E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS10005 4014093d4244f2062729de5e45e1c45c 286 SUPERFAMILY SSF53098 127 277 6.07E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS10005 4014093d4244f2062729de5e45e1c45c 286 Pfam PF00665 Integrase core domain 128 237 5.4E-25 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS10005 4014093d4244f2062729de5e45e1c45c 286 Pfam PF13276 HTH-like domain 44 99 8.1E-14 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.1E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 3.7E-68 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 SUPERFAMILY SSF50249 3 123 5.71E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 Gene3D G3DSA:2.40.50.140 1 124 3.7E-62 T 28-03-2018 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.429 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 PIRSF PIRSF002133 1 124 9.7E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03965 da917877c2482e2d6b63922383000865 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 6.6E-41 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS00870 6459e4e4db6ce3140b6dddf8e73145ec 338 SUPERFAMILY SSF53901 45 338 7.41E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00870 6459e4e4db6ce3140b6dddf8e73145ec 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 253 333 1.1E-18 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS00870 6459e4e4db6ce3140b6dddf8e73145ec 338 Gene3D G3DSA:3.40.47.10 200 338 4.4E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00870 6459e4e4db6ce3140b6dddf8e73145ec 338 Gene3D G3DSA:3.40.47.10 3 198 2.9E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00870 6459e4e4db6ce3140b6dddf8e73145ec 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 195 6.4E-8 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS11740 f904e03f9a6bfb48c47c5b5f9f7fef4d 99 Gene3D G3DSA:1.10.1330.10 57 95 6.0E-5 T 28-03-2018 SmaCSM2_RS11740 f904e03f9a6bfb48c47c5b5f9f7fef4d 99 Gene3D G3DSA:1.10.238.10 21 56 0.037 T 28-03-2018 SmaCSM2_RS11740 f904e03f9a6bfb48c47c5b5f9f7fef4d 99 SUPERFAMILY SSF47473 42 91 3.56E-6 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS11740 f904e03f9a6bfb48c47c5b5f9f7fef4d 99 ProSitePatterns PS00018 EF-hand calcium-binding domain. 50 62 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 SUPERFAMILY SSF117457 318 487 1.83E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 487 2.3E-47 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 2.7E-99 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 PIRSF PIRSF001394 1 505 1.4E-217 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 285 2.9E-61 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 Gene3D G3DSA:3.20.130.10 314 487 7.3E-65 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SmaCSM2_RS14255 da87cbbaecaf12cc1b75c85ad5ca326f 505 Pfam PF05683 Fumarase C-terminus 289 488 5.7E-79 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Gene3D G3DSA:3.40.50.20 1 123 2.1E-52 T 28-03-2018 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 SUPERFAMILY SSF51246 332 444 1.52E-42 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.2E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Gene3D G3DSA:3.30.1490.20 124 210 1.8E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.3E-228 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 SMART SM00878 336 441 4.0E-66 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 SUPERFAMILY SSF52440 1 113 4.32E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Gene3D G3DSA:3.30.470.20 211 444 3.6E-99 T 28-03-2018 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 SUPERFAMILY SSF56059 83 343 3.71E-67 T 28-03-2018 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 4.3E-39 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS19335 5ae432352570cd73762bd1e01287784e 455 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 6.6E-83 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 Gene3D G3DSA:1.10.800.10 7 297 1.3E-99 T 28-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 SUPERFAMILY SSF56534 20 293 4.45E-101 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 228 247 5.9E-13 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 196 214 5.9E-13 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 89 111 5.9E-13 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 132 143 - T 28-03-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 33 252 5.3E-48 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SmaCSM2_RS00250 730debf0b560978df9bae1c98cbe3664 297 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 27 270 1.5E-109 T 28-03-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 SmaCSM2_RS18195 1671cc38f4684f37b9794b2f226f0eae 347 Pfam PF03572 Peptidase family S41 151 320 2.8E-12 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS18195 1671cc38f4684f37b9794b2f226f0eae 347 SUPERFAMILY SSF52096 159 327 2.15E-15 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS18195 1671cc38f4684f37b9794b2f226f0eae 347 Gene3D G3DSA:3.90.226.10 92 342 2.1E-18 T 28-03-2018 SmaCSM2_RS02505 7d1ef90c3dccedf1d6ad80b6c4b2e54e 263 SUPERFAMILY SSF53335 214 261 5.79E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02505 7d1ef90c3dccedf1d6ad80b6c4b2e54e 263 SUPERFAMILY SSF53335 36 169 5.79E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02505 7d1ef90c3dccedf1d6ad80b6c4b2e54e 263 Pfam PF08241 Methyltransferase domain 65 160 2.6E-14 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS02505 7d1ef90c3dccedf1d6ad80b6c4b2e54e 263 Gene3D G3DSA:3.40.50.150 2 258 1.8E-22 T 28-03-2018 SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Gene3D G3DSA:2.160.10.10 312 437 6.1E-30 T 28-03-2018 SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 SUPERFAMILY SSF51161 253 435 2.36E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Pfam PF12804 MobA-like NTP transferase domain 7 130 1.3E-22 T 28-03-2018 IPR025877 MobA-like NTP transferase SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 5.1E-183 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 4 451 40.431 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Gene3D G3DSA:2.160.10.10 238 311 2.5E-12 T 28-03-2018 SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 SUPERFAMILY SSF53448 5 246 5.25E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 296 2.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Gene3D G3DSA:3.90.550.10 2 237 2.5E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS18675 7d2ff1b19b96005410c805480bc88bc0 455 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 394 428 2.0E-9 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS04520 7e2525fea9a926cdddad3b59b4235738 255 Gene3D G3DSA:3.60.15.10 2 244 5.4E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS04520 7e2525fea9a926cdddad3b59b4235738 255 Pfam PF12706 Beta-lactamase superfamily domain 32 200 5.5E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS04520 7e2525fea9a926cdddad3b59b4235738 255 SUPERFAMILY SSF56281 5 216 1.06E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS18805 9682c3244919ef6c3c9b5973b920a4e7 338 Gene3D G3DSA:3.30.565.10 199 310 1.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18805 9682c3244919ef6c3c9b5973b920a4e7 338 SUPERFAMILY SSF55874 202 284 1.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18805 9682c3244919ef6c3c9b5973b920a4e7 338 Pfam PF06580 Histidine kinase 146 224 4.7E-21 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SmaCSM2_RS21550 bc9a04c44b1c2b74b61d85eff1fded4b 426 Gene3D G3DSA:3.30.70.270 231 415 1.7E-44 T 28-03-2018 SmaCSM2_RS21550 bc9a04c44b1c2b74b61d85eff1fded4b 426 SMART SM00267 231 415 8.3E-36 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS21550 bc9a04c44b1c2b74b61d85eff1fded4b 426 SUPERFAMILY SSF55073 247 414 2.59E-34 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS21550 bc9a04c44b1c2b74b61d85eff1fded4b 426 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 240 350 2.0E-25 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS21550 bc9a04c44b1c2b74b61d85eff1fded4b 426 Pfam PF00990 Diguanylate cyclase, GGDEF domain 242 348 2.2E-22 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 SUPERFAMILY SSF51735 1 250 1.26E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 2.0E-61 T 28-03-2018 SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 Gene3D G3DSA:3.40.50.720 1 42 1.1E-11 T 28-03-2018 SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 Gene3D G3DSA:3.40.50.720 43 253 1.5E-61 T 28-03-2018 SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 0.0054 T 28-03-2018 SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14825 075f7fcb4c052a6b8f94607ee41b09dc 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 Pfam PF00483 Nucleotidyl transferase 6 283 1.6E-69 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 SUPERFAMILY SSF53448 4 280 4.9E-72 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 Gene3D G3DSA:2.60.120.10 335 445 5.7E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 Pfam PF01050 Mannose-6-phosphate isomerase 312 462 2.8E-74 T 28-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4 466 7.5E-222 T 28-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 SUPERFAMILY SSF51182 183 466 3.93E-89 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS02795 589dff07f0f29a8f2cb68c3222c00359 467 Gene3D G3DSA:3.90.550.10 3 334 1.1E-94 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS15215 10f8033914b0e7c5686a934b9116df1f 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 261 3.6E-53 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS15215 10f8033914b0e7c5686a934b9116df1f 340 SUPERFAMILY SSF51735 1 331 1.3E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS15215 10f8033914b0e7c5686a934b9116df1f 340 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 332 4.2E-128 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SmaCSM2_RS15215 10f8033914b0e7c5686a934b9116df1f 340 Gene3D G3DSA:3.90.25.10 181 338 2.3E-38 T 28-03-2018 SmaCSM2_RS15215 10f8033914b0e7c5686a934b9116df1f 340 Gene3D G3DSA:3.40.50.720 1 180 1.0E-32 T 28-03-2018 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 47 65 1.9E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 130 148 1.9E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Pfam PF13177 DNA polymerase III, delta subunit 26 184 4.3E-46 T 28-03-2018 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Gene3D G3DSA:1.20.272.10 249 365 1.5E-12 T 28-03-2018 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 9 358 6.4E-127 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 239 364 9.1E-29 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Gene3D G3DSA:3.40.50.300 6 172 7.6E-42 T 28-03-2018 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 SMART SM00382 43 194 4.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 SUPERFAMILY SSF52540 40 229 1.53E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Gene3D G3DSA:1.10.8.60 173 248 2.2E-17 T 28-03-2018 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 SUPERFAMILY SSF48019 249 365 1.87E-30 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SmaCSM2_RS04725 f02dd77a91fab90c908a322628e65ea0 688 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 554 683 6.4E-10 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 Pfam PF00303 Thymidylate synthase 3 264 4.2E-123 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 SUPERFAMILY SSF55831 1 264 1.02E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 40.874 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 4.6E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 4.6E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 4.6E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 4.6E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 4.6E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 Gene3D G3DSA:3.30.572.10 1 264 4.1E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 85 1.4E-42 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS03530 4f546b2e18fa2745ca65d3fdf4eb489b 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 7.1E-99 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 SUPERFAMILY SSF53383 11 401 5.98E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 15 401 8.4E-142 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 Gene3D G3DSA:3.40.640.10 168 293 7.1E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 402 44.8 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 Gene3D G3DSA:3.90.1150.10 294 407 4.4E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 PIRSF PIRSF000521 174 404 1.0E-33 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 PIRSF PIRSF000521 22 159 7.7E-9 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 Pfam PF00202 Aminotransferase class-III 23 401 1.3E-116 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17545 08251ae14342f6efbe93f686f8081265 408 Gene3D G3DSA:3.90.1150.10 1 164 9.0E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 Pfam PF00072 Response regulator receiver domain 22 132 1.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 SMART SM00448 20 132 3.1E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 SUPERFAMILY SSF52172 19 145 1.85E-40 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 Gene3D G3DSA:1.10.10.10 141 245 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 Gene3D G3DSA:3.40.50.2300 7 140 7.0E-37 T 28-03-2018 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 240 1.7E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 SMART SM00862 166 240 6.3E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS03480 f9beaad1a69242996b91dfc4fdea5408 248 SUPERFAMILY SSF46894 141 240 8.79E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 133 3.4E-45 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 133 5.9E-46 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 SUPERFAMILY SSF81330 12 129 4.58E-37 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 134 26.401 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 5.0E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 89 97 5.0E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 98 107 5.0E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SmaCSM2_RS17060 1734227897ec89179309908ed29d7cbb 134 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 246 252 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Gene3D G3DSA:3.30.160.70 109 193 5.4E-21 T 28-03-2018 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 SUPERFAMILY SSF53155 116 194 4.51E-19 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 SUPERFAMILY SSF46689 10 58 1.3E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Gene3D G3DSA:1.10.10.60 66 108 3.5E-4 T 28-03-2018 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 SUPERFAMILY SSF46767 195 276 6.67E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Gene3D G3DSA:1.10.10.10 194 280 7.0E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 196 275 1.3E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Pfam PF12833 Helix-turn-helix domain 32 109 2.0E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 119 177 7.4E-5 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Gene3D G3DSA:1.10.10.60 7 65 2.1E-15 T 28-03-2018 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 197 276 7.1E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14830 7f54ff166a11584563e3ff964c8102ab 280 SMART SM00342 26 108 5.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 SUPERFAMILY SSF53850 91 298 2.9E-40 T 28-03-2018 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 SUPERFAMILY SSF46785 5 87 8.71E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 Gene3D G3DSA:1.10.10.10 3 87 3.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 Gene3D G3DSA:3.40.190.10 178 266 2.2E-24 T 28-03-2018 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 Pfam PF03466 LysR substrate binding domain 91 295 3.0E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07850 c7ad2daebd3663e0db9af6f0df265698 310 Gene3D G3DSA:3.40.190.10 92 177 8.6E-11 T 28-03-2018 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 Gene3D G3DSA:3.40.190.10 87 178 1.1E-19 T 28-03-2018 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 SUPERFAMILY SSF53850 88 290 9.01E-40 T 28-03-2018 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 Pfam PF03466 LysR substrate binding domain 87 288 5.0E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 Gene3D G3DSA:3.40.190.10 179 266 9.9E-22 T 28-03-2018 SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 SUPERFAMILY SSF46785 2 87 4.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 Gene3D G3DSA:1.10.10.10 1 83 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01575 5a4c15285dda2ca9bce97928f41dedd1 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS02895 4aa89a1fa347ab194ed3076f797fa089 141 Gene3D G3DSA:3.40.50.10110 1 141 3.0E-39 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 SmaCSM2_RS02895 4aa89a1fa347ab194ed3076f797fa089 141 SUPERFAMILY SSF102400 1 140 6.67E-35 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 SmaCSM2_RS02895 4aa89a1fa347ab194ed3076f797fa089 141 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 136 3.0E-33 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 SMART SM00855 4 190 1.3E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 124 1.2E-28 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 136 209 3.6E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 SUPERFAMILY SSF53254 2 246 1.57E-78 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 2 229 44.643 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 4 247 2.8E-120 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 PIRSF PIRSF000709 173 241 6.4E-4 T 28-03-2018 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 PIRSF PIRSF000709 1 114 3.4E-8 T 28-03-2018 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SmaCSM2_RS06300 40f204abbfaf4ff0222715bbc96344d7 249 Gene3D G3DSA:3.40.50.1240 1 249 2.5E-67 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Gene3D G3DSA:1.10.287.130 180 250 3.9E-19 T 28-03-2018 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SUPERFAMILY SSF47226 598 709 7.72E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Pfam PF00072 Response regulator receiver domain 462 574 2.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Gene3D G3DSA:3.30.565.10 259 422 1.6E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SMART SM00388 190 255 8.3E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Pfam PF01627 Hpt domain 623 693 3.4E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SUPERFAMILY SSF47384 173 256 4.12E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SMART SM00448 460 575 1.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 417 2.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Gene3D G3DSA:3.40.50.2300 451 590 4.5E-36 T 28-03-2018 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SUPERFAMILY SSF55874 245 420 1.44E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SUPERFAMILY SSF52172 458 584 2.85E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SMART SM00073 612 710 1.2E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Pfam PF00512 His Kinase A (phospho-acceptor) domain 190 255 2.2E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 SMART SM00387 302 419 6.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09905 7d7d67075ea86394a916951b9cd84fd7 724 Gene3D G3DSA:1.20.120.160 591 710 2.1E-12 T 28-03-2018 SmaCSM2_RS11350 d4bd45d41092bdc78919adc3120f07e6 373 SUPERFAMILY SSF54506 175 353 1.46E-56 T 28-03-2018 SmaCSM2_RS11350 d4bd45d41092bdc78919adc3120f07e6 373 Gene3D G3DSA:3.10.310.10 3 178 1.2E-75 T 28-03-2018 SmaCSM2_RS11350 d4bd45d41092bdc78919adc3120f07e6 373 SUPERFAMILY SSF54506 5 171 7.85E-67 T 28-03-2018 SmaCSM2_RS11350 d4bd45d41092bdc78919adc3120f07e6 373 Gene3D G3DSA:3.10.310.10 179 337 8.0E-53 T 28-03-2018 SmaCSM2_RS11350 d4bd45d41092bdc78919adc3120f07e6 373 Pfam PF04303 PrpF protein 6 353 8.0E-136 T 28-03-2018 IPR007400 PrpF protein SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 SUPERFAMILY SSF46894 143 210 1.97E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 Gene3D G3DSA:1.10.10.10 128 213 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 SMART SM00448 3 116 5.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 Gene3D G3DSA:3.40.50.2300 2 127 7.8E-33 T 28-03-2018 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 203 5.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 Pfam PF00072 Response regulator receiver domain 5 116 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 SMART SM00421 146 203 2.5E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08390 5c51d2e5a7f4aa103989269838183800 215 SUPERFAMILY SSF52172 2 132 2.42E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09655 65df549e5bb71ab47558c7b99937ab14 408 Gene3D G3DSA:1.50.10.10 3 408 9.0E-88 T 28-03-2018 SmaCSM2_RS09655 65df549e5bb71ab47558c7b99937ab14 408 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 34 399 8.3E-119 T 28-03-2018 SmaCSM2_RS09655 65df549e5bb71ab47558c7b99937ab14 408 SUPERFAMILY SSF48208 6 407 5.33E-119 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 SUPERFAMILY SSF46689 205 253 7.53E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 219 234 3.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 234 250 3.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 Gene3D G3DSA:1.10.10.60 206 264 2.2E-10 T 28-03-2018 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 Gene3D G3DSA:2.60.120.10 7 93 1.5E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 Pfam PF12833 Helix-turn-helix domain 174 251 1.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 SUPERFAMILY SSF51182 6 145 2.77E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 SMART SM00342 168 250 6.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10985 685744d936af7e4916e88b0b500bbf5c 265 Gene3D G3DSA:1.10.10.60 149 205 9.1E-9 T 28-03-2018 SmaCSM2_RS00850 eaddc1b08fd0a24b78898c1d1cae2edf 159 Gene3D G3DSA:3.40.1280.10 1 158 2.1E-38 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS00850 eaddc1b08fd0a24b78898c1d1cae2edf 159 Pfam PF00588 SpoU rRNA Methylase family 7 147 3.0E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS00850 eaddc1b08fd0a24b78898c1d1cae2edf 159 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 7 156 33.848 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SmaCSM2_RS00850 eaddc1b08fd0a24b78898c1d1cae2edf 159 PIRSF PIRSF029256 6 159 7.3E-64 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SmaCSM2_RS00850 eaddc1b08fd0a24b78898c1d1cae2edf 159 SUPERFAMILY SSF75217 7 157 5.95E-44 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS15680 640b0afb5d0127bc3cec97030088725d 261 Pfam PF02592 Putative vitamin uptake transporter 65 237 6.7E-42 T 28-03-2018 IPR003744 Queuosine precursor transporter SmaCSM2_RS15680 640b0afb5d0127bc3cec97030088725d 261 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 61 242 8.1E-34 T 28-03-2018 IPR003744 Queuosine precursor transporter SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 10 452 1.1E-88 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Gene3D G3DSA:3.40.1190.10 106 311 3.2E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Pfam PF08245 Mur ligase middle domain 120 289 2.1E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Gene3D G3DSA:3.90.190.20 312 453 6.2E-25 T 28-03-2018 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Gene3D G3DSA:3.40.50.720 10 98 7.3E-6 T 28-03-2018 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 SUPERFAMILY SSF53623 117 307 1.06E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 SUPERFAMILY SSF53244 310 453 7.63E-26 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 380 1.1E-5 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS05385 9761c1bcb287967610684ad03cadd260 469 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 9 456 27.02 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS12025 61f1369527478016930b0d488fe5606a 134 SUPERFAMILY SSF52172 12 125 1.24E-17 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS12025 61f1369527478016930b0d488fe5606a 134 SMART SM00448 14 120 8.2E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS12025 61f1369527478016930b0d488fe5606a 134 Gene3D G3DSA:3.40.50.2300 9 131 4.6E-13 T 28-03-2018 SmaCSM2_RS12025 61f1369527478016930b0d488fe5606a 134 Pfam PF00072 Response regulator receiver domain 16 95 1.7E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 327 55.21 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 SUPERFAMILY SSF56327 159 327 8.49E-56 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 Gene3D G3DSA:3.90.110.10 158 325 4.5E-46 T 28-03-2018 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 159 321 1.4E-28 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 Gene3D G3DSA:3.40.50.720 6 157 1.1E-29 T 28-03-2018 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 154 7.9E-36 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 SUPERFAMILY SSF51735 3 157 2.32E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 PIRSF PIRSF000102 1 326 6.2E-62 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SmaCSM2_RS04165 fa287f3b666b5d034fa8ab8a2f7d3b27 328 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 321 8.0E-140 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 14 356 3.3E-117 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 Gene3D G3DSA:3.10.180.10 159 356 8.6E-58 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 PIRSF PIRSF009283 1 356 1.4E-123 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 164 274 1.6E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 SUPERFAMILY SSF54593 1 343 1.38E-67 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 Gene3D G3DSA:3.10.180.10 3 158 5.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19795 ca8279e041045b4c47add86dc3358e42 356 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 6 147 5.4E-61 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 Gene3D G3DSA:1.20.1250.20 9 204 1.1E-26 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 1.5E-5 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 1.5E-5 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 1.5E-5 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 Pfam PF07690 Major Facilitator Superfamily 23 411 5.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 Gene3D G3DSA:1.20.1250.20 255 500 1.7E-16 T 28-03-2018 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 89 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 SUPERFAMILY SSF103473 10 201 3.66E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 SUPERFAMILY SSF103473 251 422 3.66E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS04920 4cc8d60e47a1b3109932439f9909635e 505 SUPERFAMILY SSF103473 469 495 3.66E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS09430 21b14d47a272646bfe20cd09234493b3 119 SUPERFAMILY SSF52172 5 117 1.85E-23 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09430 21b14d47a272646bfe20cd09234493b3 119 Pfam PF00072 Response regulator receiver domain 8 115 4.5E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09430 21b14d47a272646bfe20cd09234493b3 119 SMART SM00448 6 116 2.1E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09430 21b14d47a272646bfe20cd09234493b3 119 Gene3D G3DSA:3.40.50.2300 1 118 2.9E-24 T 28-03-2018 SmaCSM2_RS01945 5bc08f639d0b7235012333a231446637 513 Gene3D G3DSA:3.40.710.10 8 365 5.6E-75 T 28-03-2018 SmaCSM2_RS01945 5bc08f639d0b7235012333a231446637 513 Pfam PF00144 Beta-lactamase 20 361 2.3E-63 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS01945 5bc08f639d0b7235012333a231446637 513 SUPERFAMILY SSF56601 17 361 1.25E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS01945 5bc08f639d0b7235012333a231446637 513 Pfam PF11954 Domain of unknown function (DUF3471) 401 501 2.9E-7 T 28-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal SmaCSM2_RS09530 d7eb0f7af0409096c2032052b2857100 102 PIRSF PIRSF012508 4 102 2.9E-29 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD SmaCSM2_RS09530 d7eb0f7af0409096c2032052b2857100 102 Pfam PF01371 Trp repressor protein 15 99 1.4E-26 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS09530 d7eb0f7af0409096c2032052b2857100 102 SUPERFAMILY SSF48295 8 99 1.1E-23 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 SmaCSM2_RS09530 d7eb0f7af0409096c2032052b2857100 102 Gene3D G3DSA:1.10.1270.10 1 102 5.4E-23 T 28-03-2018 SmaCSM2_RS09530 d7eb0f7af0409096c2032052b2857100 102 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 15 99 1.8E-16 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 7.0E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 7.6E-133 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 Gene3D G3DSA:3.10.20.70 2 103 3.8E-27 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 SUPERFAMILY SSF55931 103 467 7.85E-132 T 28-03-2018 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 467 3.9E-194 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 SUPERFAMILY SSF54368 3 101 1.31E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 Gene3D G3DSA:3.30.590.10 105 458 4.9E-119 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SmaCSM2_RS00620 2ba8a648b15017fab01d245d0e5238b3 469 SMART SM01230 102 379 4.7E-140 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS18680 e8dfa742d7ea9b3936bd1b38add1d23a 127 Pfam PF04138 GtrA-like protein 10 126 9.5E-16 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SmaCSM2_RS21480 2cb1c9bd38ec561864aa3e247cb435bc 284 Pfam PF12697 Alpha/beta hydrolase family 27 272 1.5E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS21480 2cb1c9bd38ec561864aa3e247cb435bc 284 SUPERFAMILY SSF53474 5 279 5.68E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS21480 2cb1c9bd38ec561864aa3e247cb435bc 284 Gene3D G3DSA:3.40.50.1820 2 277 2.8E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS02025 7de1da60da64189e11e1fbaf6cac32db 196 Gene3D G3DSA:3.40.109.10 9 196 2.5E-34 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS02025 7de1da60da64189e11e1fbaf6cac32db 196 Pfam PF00881 Nitroreductase family 16 158 5.3E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SmaCSM2_RS02025 7de1da60da64189e11e1fbaf6cac32db 196 SUPERFAMILY SSF55469 10 195 2.49E-43 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS02025 7de1da60da64189e11e1fbaf6cac32db 196 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 196 48.141 T 28-03-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PIRSF PIRSF004862 11 548 3.7E-139 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 Pfam PF01514 Secretory protein of YscJ/FliF family 37 227 3.2E-63 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 11 548 3.1E-87 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 Gene3D G3DSA:3.30.70.1530 58 120 8.4E-5 T 28-03-2018 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PRINTS PR01009 Flagellar M-ring protein signature 128 146 6.7E-33 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PRINTS PR01009 Flagellar M-ring protein signature 203 221 6.7E-33 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PRINTS PR01009 Flagellar M-ring protein signature 345 369 6.7E-33 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PRINTS PR01009 Flagellar M-ring protein signature 160 174 6.7E-33 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 PRINTS PR01009 Flagellar M-ring protein signature 273 291 6.7E-33 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 SmaCSM2_RS10180 1f1e615e6cb13cadd250fba151d19e1f 548 Pfam PF08345 Flagellar M-ring protein C-terminal 260 421 2.2E-49 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 Gene3D G3DSA:1.10.10.10 125 229 3.1E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 SUPERFAMILY SSF46894 127 225 2.66E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 SUPERFAMILY SSF52172 3 125 2.28E-42 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 SMART SM00862 150 225 8.3E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 2 226 1.8E-112 T 28-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 SMART SM00448 3 116 1.2E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 Gene3D G3DSA:3.40.50.2300 1 124 9.9E-38 T 28-03-2018 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS04330 916a35e524dc418361d66d9758ac278f 229 Pfam PF00072 Response regulator receiver domain 5 117 7.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 SUPERFAMILY SSF56601 43 298 1.8E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 52 277 4.5E-78 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 298 387 3.6E-24 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 SMART SM00936 298 388 4.1E-32 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 Gene3D G3DSA:2.60.410.10 298 388 1.4E-22 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 Gene3D G3DSA:3.40.710.10 42 297 2.0E-46 T 28-03-2018 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 SUPERFAMILY SSF69189 298 390 2.35E-24 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 155 2.5E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 165 178 2.5E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS18340 bbb7def86a51d1730725177bc2aa709c 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 80 91 2.5E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF47384 351 433 8.83E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF13185 GAF domain 134 265 8.1E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF52172 912 1032 1.41E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF55874 421 591 1.83E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:3.30.565.10 437 600 1.9E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 3.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 3.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 3.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 3.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:3.40.50.2300 906 1034 3.3E-39 T 28-03-2018 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00387 479 591 1.1E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:3.40.50.2300 764 905 3.7E-18 T 28-03-2018 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00065 133 275 5.4E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00448 646 756 2.7E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00448 768 882 2.3E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00448 914 1027 3.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF52172 766 890 2.56E-18 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SMART SM00388 364 432 3.1E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 432 5.2E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF52172 647 761 1.99E-25 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:1.10.287.130 355 428 2.3E-15 T 28-03-2018 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:3.40.50.2300 640 763 2.8E-23 T 28-03-2018 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 590 6.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF00072 Response regulator receiver domain 916 1025 2.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF00072 Response regulator receiver domain 771 872 1.6E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Pfam PF00072 Response regulator receiver domain 648 757 8.9E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 SUPERFAMILY SSF55781 103 265 1.88E-16 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS09440 0498fd048dc1e6250240ab8f5d60e625 1034 Gene3D G3DSA:3.30.450.40 108 305 4.4E-17 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS09400 2b65122e1185af658e96881474ff5edf 186 Gene3D G3DSA:3.40.630.30 1 178 3.2E-26 T 28-03-2018 SmaCSM2_RS09400 2b65122e1185af658e96881474ff5edf 186 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 2.6E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS09400 2b65122e1185af658e96881474ff5edf 186 SUPERFAMILY SSF55729 1 155 2.6E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Gene3D G3DSA:3.20.20.60 521 835 1.1E-91 T 28-03-2018 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 53 69 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 SUPERFAMILY SSF47831 312 411 1.57E-23 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 456 467 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 714 732 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 276 831 6.0E-138 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 200 215 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Gene3D G3DSA:3.50.30.10 420 514 1.7E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 SUPERFAMILY SSF55804 11 146 7.98E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 SUPERFAMILY SSF52009 396 519 2.62E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 166 242 1.9E-17 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Gene3D G3DSA:3.40.930.10 9 148 1.1E-26 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 SUPERFAMILY SSF51621 526 816 2.12E-98 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 SUPERFAMILY SSF55594 165 243 3.4E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 523 805 1.7E-105 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Pfam PF05524 PEP-utilising enzyme, N-terminal 278 396 9.2E-20 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 731 746 4.9E-22 T 28-03-2018 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 767 779 4.9E-22 T 28-03-2018 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 714 729 4.9E-22 T 28-03-2018 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 565 584 4.9E-22 T 28-03-2018 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR00107 Phosphocarrier protein signature 214 231 7.7E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR00107 Phosphocarrier protein signature 199 214 7.7E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 PRINTS PR00107 Phosphocarrier protein signature 174 190 7.7E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 174 181 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Pfam PF00381 PTS HPr component phosphorylation site 166 242 1.9E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 11 145 6.1E-27 T 28-03-2018 IPR002178 PTS EIIA type-2 domain SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Pfam PF00391 PEP-utilising enzyme, mobile domain 427 497 3.2E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Gene3D G3DSA:1.10.274.10 307 414 1.9E-24 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS11265 ea9399fae7fa9d5c763d4a2d38fe361c 836 Gene3D G3DSA:3.30.1340.10 163 245 2.7E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 Gene3D G3DSA:3.90.1150.10 255 398 2.5E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 Gene3D G3DSA:3.40.640.10 9 254 2.3E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 PIRSF PIRSF001434 1 396 5.1E-131 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 12 394 4.6E-177 T 28-03-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 SUPERFAMILY SSF53383 18 394 1.77E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS16310 610f88a341e8f85994a275e64b404124 411 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 393 8.7E-133 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Gene3D G3DSA:3.40.50.10750 571 724 5.6E-48 T 28-03-2018 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Pfam PF01515 Phosphate acetyl/butaryl transferase 428 748 8.4E-92 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 PIRSF PIRSF036684 1 756 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Pfam PF00390 Malic enzyme, N-terminal domain 20 152 3.1E-27 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 SUPERFAMILY SSF53659 428 751 1.19E-88 T 28-03-2018 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 SUPERFAMILY SSF51735 164 451 1.01E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Gene3D G3DSA:3.40.50.10380 6 161 5.9E-35 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Pfam PF03949 Malic enzyme, NAD binding domain 166 363 1.9E-21 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 Gene3D G3DSA:3.40.50.720 162 446 7.1E-84 T 28-03-2018 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 SUPERFAMILY SSF53223 11 162 1.15E-51 T 28-03-2018 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 SMART SM00919 164 399 1.6E-130 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SmaCSM2_RS17865 94afa1883589c177e09d00c736cf260c 763 SMART SM01274 19 152 5.1E-77 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 1.5E-48 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 Gene3D G3DSA:1.10.40.30 391 445 2.0E-29 T 28-03-2018 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 4.2E-17 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 4.2E-17 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 4.2E-17 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 4.2E-17 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 SUPERFAMILY SSF48557 2 447 3.77E-101 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 454 1.5E-119 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 Gene3D G3DSA:1.10.275.10 1 117 1.2E-42 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 Pfam PF00206 Lyase 14 312 1.5E-62 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SmaCSM2_RS14105 c0a4ff54ecffc2637817bcbb34f6a216 455 Gene3D G3DSA:1.20.200.10 118 390 1.7E-83 T 28-03-2018 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 SUPERFAMILY SSF56935 49 203 9.52E-65 T 28-03-2018 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 SUPERFAMILY SSF56935 301 775 9.52E-65 T 28-03-2018 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 135 9.9E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 Gene3D G3DSA:2.170.130.10 16 141 8.6E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 Gene3D G3DSA:2.40.170.20 164 775 5.0E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08170 efa3653f5e449bab340bec2c636839fe 776 Pfam PF00593 TonB dependent receptor 282 775 7.5E-34 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 1.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 SUPERFAMILY SSF53850 101 291 1.54E-26 T 28-03-2018 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 Gene3D G3DSA:1.10.10.10 8 94 2.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 Gene3D G3DSA:3.40.190.10 95 221 4.4E-17 T 28-03-2018 SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 SUPERFAMILY SSF46785 7 119 1.26E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12850 2f9e3738abffb02a1a5af34969a2604e 293 Pfam PF03466 LysR substrate binding domain 100 286 3.1E-28 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS05880 837b68984c1e7c06d3cf1aab410e6dbd 135 SUPERFAMILY SSF54637 10 133 1.15E-34 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS05880 837b68984c1e7c06d3cf1aab410e6dbd 135 Pfam PF13279 Thioesterase-like superfamily 15 132 8.3E-22 T 28-03-2018 SmaCSM2_RS05880 837b68984c1e7c06d3cf1aab410e6dbd 135 Gene3D G3DSA:3.10.129.10 9 135 4.8E-35 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Gene3D G3DSA:3.20.20.10 514 736 4.9E-53 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 SUPERFAMILY SSF55021 388 460 1.37E-9 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 10 459 1.0E-82 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 499 860 1.1E-91 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Gene3D G3DSA:3.30.70.260 297 388 2.0E-14 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 842 855 8.2E-23 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 663 676 8.2E-23 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 741 760 8.2E-23 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 554 566 8.2E-23 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 534 552 8.2E-23 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01181 Diaminopimelate decarboxylase signature 638 647 4.3E-12 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01181 Diaminopimelate decarboxylase signature 852 864 4.3E-12 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01181 Diaminopimelate decarboxylase signature 769 787 4.3E-12 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PRINTS PR01181 Diaminopimelate decarboxylase signature 552 569 4.3E-12 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 ProSitePatterns PS00324 Aspartokinase signature. 12 20 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 534 552 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 520 751 1.4E-42 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 SUPERFAMILY SSF53633 9 303 2.96E-57 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Pfam PF00696 Amino acid kinase family 10 290 9.3E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 SUPERFAMILY SSF55021 311 404 2.67E-12 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Gene3D G3DSA:3.40.1160.10 7 296 1.3E-57 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Gene3D G3DSA:3.30.70.260 389 461 1.3E-9 T 28-03-2018 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 694 710 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 731 842 5.4E-22 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 PIRSF PIRSF036459 1 864 0.0 T 28-03-2018 IPR011246 Bifunctional diaminopimelate decarboxylase/aspartate kinase SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 Gene3D G3DSA:2.40.37.10 737 864 3.2E-34 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 SUPERFAMILY SSF50621 731 862 1.09E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS05375 760e75133aaa8d676f2c3463722e99cb 864 SUPERFAMILY SSF51419 505 753 5.52E-59 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 63 17.354 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 2.0E-19 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 SUPERFAMILY SSF63562 1 77 7.46E-24 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 SMART SM01409 8 62 7.6E-17 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 Pfam PF01192 RNA polymerase Rpb6 8 60 6.2E-17 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SmaCSM2_RS17375 72395a4691c836e2d35d50e8ef14d081 99 Gene3D G3DSA:3.90.940.10 1 94 6.6E-26 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SmaCSM2_RS20705 3f62dcd70364d23f49f9a52df8f6bb13 398 Gene3D G3DSA:1.20.1600.10 41 383 1.3E-29 T 28-03-2018 SmaCSM2_RS20705 3f62dcd70364d23f49f9a52df8f6bb13 398 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 373 4.8E-82 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS20705 3f62dcd70364d23f49f9a52df8f6bb13 398 SUPERFAMILY SSF111369 51 296 8.5E-78 T 28-03-2018 SmaCSM2_RS20705 3f62dcd70364d23f49f9a52df8f6bb13 398 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 290 1.4E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 SUPERFAMILY SSF52518 58 214 2.88E-12 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 742 929 3.0E-23 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Gene3D G3DSA:3.40.920.10 733 945 2.6E-51 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 SUPERFAMILY SSF52922 280 409 5.61E-9 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 468 554 5.3E-5 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 SUPERFAMILY SSF52518 448 635 9.71E-13 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Gene3D G3DSA:3.40.50.920 284 413 1.5E-8 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 SUPERFAMILY SSF53323 734 935 2.62E-28 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Gene3D G3DSA:3.40.50.970 29 283 1.3E-16 T 28-03-2018 SmaCSM2_RS00545 96cfa02b14b6679876e70ebe47487ecf 1228 Gene3D G3DSA:3.40.50.970 453 633 5.9E-33 T 28-03-2018 SmaCSM2_RS00940 c3fb55dfecbf7d73a801d6c086c500ff 247 Gene3D G3DSA:3.30.2350.10 18 243 2.0E-50 T 28-03-2018 SmaCSM2_RS00940 c3fb55dfecbf7d73a801d6c086c500ff 247 Pfam PF00849 RNA pseudouridylate synthase 27 178 1.8E-27 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS00940 c3fb55dfecbf7d73a801d6c086c500ff 247 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 66 80 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS00940 c3fb55dfecbf7d73a801d6c086c500ff 247 SUPERFAMILY SSF55120 14 244 1.1E-49 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Gene3D G3DSA:3.50.50.60 244 323 1.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Gene3D G3DSA:3.50.50.60 324 401 6.6E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 SUPERFAMILY SSF46548 7 158 1.62E-36 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Gene3D G3DSA:1.10.1060.10 3 145 3.6E-35 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 29 135 2.0E-36 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Gene3D G3DSA:3.40.50.720 402 481 8.7E-9 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 7 479 4.4E-236 T 28-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 PRINTS PR00419 Adrenodoxin reductase family signature 333 346 1.0E-28 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 PRINTS PR00419 Adrenodoxin reductase family signature 299 313 1.0E-28 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 PRINTS PR00419 Adrenodoxin reductase family signature 149 171 1.0E-28 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 PRINTS PR00419 Adrenodoxin reductase family signature 172 185 1.0E-28 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 SUPERFAMILY SSF51971 147 410 4.77E-65 T 28-03-2018 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 149 468 8.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00405 62f58b97b9ec8385123d80bf77b33100 481 Gene3D G3DSA:3.40.50.720 146 243 9.9E-17 T 28-03-2018 SmaCSM2_RS08120 8dc779fa6ade3960bce806aecf81eccb 91 SUPERFAMILY SSF50182 7 69 5.01E-24 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS08120 8dc779fa6ade3960bce806aecf81eccb 91 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.333 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 SmaCSM2_RS08120 8dc779fa6ade3960bce806aecf81eccb 91 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 9.4E-30 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 SmaCSM2_RS08120 8dc779fa6ade3960bce806aecf81eccb 91 Pfam PF17209 Hfq protein 7 69 7.6E-31 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 SmaCSM2_RS08120 8dc779fa6ade3960bce806aecf81eccb 91 Gene3D G3DSA:2.30.30.100 4 72 1.3E-32 T 28-03-2018 SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 Gene3D G3DSA:3.90.1150.10 259 391 7.1E-55 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 Gene3D G3DSA:3.40.640.10 11 257 2.1E-62 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 SUPERFAMILY SSF53383 16 389 1.05E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 389 1.1E-159 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS02665 ab576cbbe14cec0035482a2c1d62f836 391 PIRSF PIRSF001434 1 391 4.4E-147 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SUPERFAMILY SSF51126 46 441 9.42E-48 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SUPERFAMILY SSF103515 482 773 3.14E-38 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SMART SM00869 500 763 7.4E-26 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 333 773 8.4E-86 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 Pfam PF03797 Autotransporter beta-domain 503 751 4.7E-35 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SMART SM00710 141 173 3700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SMART SM00710 207 229 4400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SMART SM00710 91 113 3.7 T 28-03-2018 IPR006626 Parallel beta-helix repeat SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 SMART SM00710 174 196 1000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 PRINTS PR01482 Pertactin signature 20 37 4.7E-7 T 28-03-2018 IPR003992 Pertactin GO:0007155 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 PRINTS PR01482 Pertactin signature 300 324 4.7E-7 T 28-03-2018 IPR003992 Pertactin GO:0007155 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 PRINTS PR01482 Pertactin signature 367 384 4.7E-7 T 28-03-2018 IPR003992 Pertactin GO:0007155 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 Gene3D G3DSA:2.40.128.130 468 773 4.3E-37 T 28-03-2018 SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 Gene3D G3DSA:2.160.20.20 18 443 1.7E-73 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS11980 8f3a3a024aea865c51d791aada65825c 773 Pfam PF03212 Pertactin 318 437 4.1E-7 T 28-03-2018 IPR004899 Pertactin, central region SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 Gene3D G3DSA:3.30.540.10 2 160 5.1E-42 T 28-03-2018 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 10 254 7.4E-92 T 28-03-2018 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 Pfam PF00459 Inositol monophosphatase family 8 244 6.5E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 SUPERFAMILY SSF56655 7 260 5.5E-75 T 28-03-2018 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS16445 cee3de00a79558d2cd1e880df0ff257e 267 Gene3D G3DSA:3.40.190.80 161 259 1.1E-31 T 28-03-2018 SmaCSM2_RS11790 8ca0633106fb0451907b7ecf333b11a4 479 Gene3D G3DSA:1.20.5.340 74 392 0.078 T 28-03-2018 SmaCSM2_RS11790 8ca0633106fb0451907b7ecf333b11a4 479 Gene3D G3DSA:1.20.5.340 1 73 0.21 T 28-03-2018 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 SMART SM00869 841 1106 5.8E-45 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 194 207 4.2E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 430 446 4.2E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 112 131 4.2E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 650 1116 1.7E-43 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 SUPERFAMILY SSF103515 802 1116 1.26E-58 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 Gene3D G3DSA:3.40.50.200 81 496 1.6E-55 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 Gene3D G3DSA:2.40.128.130 793 1116 4.2E-48 T 28-03-2018 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 Pfam PF03797 Autotransporter beta-domain 844 1096 9.0E-51 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 SUPERFAMILY SSF52743 93 135 2.09E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 SUPERFAMILY SSF52743 191 491 2.09E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 Pfam PF00082 Subtilase family 112 481 1.1E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS18895 2852b6bcd9587ba952c9a0bf625edc97 1116 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 431 441 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 SUPERFAMILY SSF56425 240 358 2.39E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Pfam PF02910 Fumarate reductase flavoprotein C-term 463 596 2.5E-43 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Pfam PF00890 FAD binding domain 12 408 1.0E-121 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Gene3D G3DSA:1.20.58.100 434 543 7.6E-33 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 PIRSF PIRSF000171 1 586 1.6E-37 T 28-03-2018 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 SUPERFAMILY SSF46977 454 596 9.94E-49 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 9 596 2.1E-287 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 12 596 6.9E-240 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 SUPERFAMILY SSF51905 4 263 1.24E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 SUPERFAMILY SSF51905 362 434 1.24E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Gene3D G3DSA:4.10.80.40 544 596 1.2E-20 T 28-03-2018 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Gene3D G3DSA:3.50.50.60 2 297 1.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 Gene3D G3DSA:3.50.50.60 298 433 1.9E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08445 28b999a93a04d159509b0eac3a7414e7 596 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 46 55 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 634 36.214 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Gene3D G3DSA:3.30.420.40 1 198 5.8E-82 T 28-03-2018 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Gene3D G3DSA:2.60.34.10 392 534 1.3E-62 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Gene3D G3DSA:1.20.1270.10 535 620 2.9E-18 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 471 487 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 367 387 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 390 409 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 139 159 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 200 210 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 PRINTS PR00301 70kDa heat shock protein signature 336 352 1.1E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 SUPERFAMILY SSF100920 386 542 1.12E-58 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 SUPERFAMILY SSF53067 1 184 4.53E-66 T 28-03-2018 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 194 207 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Pfam PF00012 Hsp70 protein 4 603 8.4E-260 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 602 9.9E-283 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 Gene3D G3DSA:3.30.420.40 199 368 5.2E-47 T 28-03-2018 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 339 353 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SmaCSM2_RS08750 dd5faa97a69333fc96c9c101bcea8f6c 640 SUPERFAMILY SSF53067 189 384 2.16E-67 T 28-03-2018 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 Gene3D G3DSA:1.10.3080.10 13 435 1.2E-77 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 SUPERFAMILY SSF81340 6 433 1.31E-90 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 82 99 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 335 355 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 364 380 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 168 187 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 382 401 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 PRINTS PR00762 Chloride channel signature 116 135 2.9E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20635 40dd79f5cc4dcb45458421946be46757 447 Pfam PF00654 Voltage gated chloride channel 70 414 1.2E-79 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS18120 fc3dc3c429e423b7d41505deef26589d 278 Gene3D G3DSA:3.40.30.10 90 278 8.1E-37 T 28-03-2018 SmaCSM2_RS18120 fc3dc3c429e423b7d41505deef26589d 278 Pfam PF01323 DSBA-like thioredoxin domain 144 262 1.0E-11 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SmaCSM2_RS18120 fc3dc3c429e423b7d41505deef26589d 278 SUPERFAMILY SSF52833 87 264 1.68E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14075 9bd339bc1fec75de8f1dbdd48bd23ff1 291 SMART SM00382 34 212 8.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS14075 9bd339bc1fec75de8f1dbdd48bd23ff1 291 Pfam PF00005 ABC transporter 25 162 6.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS14075 9bd339bc1fec75de8f1dbdd48bd23ff1 291 Gene3D G3DSA:3.40.50.300 6 252 8.6E-48 T 28-03-2018 SmaCSM2_RS14075 9bd339bc1fec75de8f1dbdd48bd23ff1 291 SUPERFAMILY SSF52540 7 225 7.14E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09590 1f9b62cc83e7355ad7feeeef92c0e855 332 Pfam PF01112 Asparaginase 44 317 1.9E-76 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 SmaCSM2_RS09590 1f9b62cc83e7355ad7feeeef92c0e855 332 SUPERFAMILY SSF56235 32 317 5.12E-82 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS09590 1f9b62cc83e7355ad7feeeef92c0e855 332 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 1 23 3.6E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SmaCSM2_RS09590 1f9b62cc83e7355ad7feeeef92c0e855 332 Gene3D G3DSA:3.60.20.30 187 326 1.8E-40 T 28-03-2018 SmaCSM2_RS15965 64cfdb9b2d70f60f1d0b9c1f7f9b50d2 292 SUPERFAMILY SSF89069 24 91 7.72E-14 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 SmaCSM2_RS15965 64cfdb9b2d70f60f1d0b9c1f7f9b50d2 292 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 25 98 4.6E-15 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 SmaCSM2_RS10775 401f80f4c7b1cedeb47ee231bf725ecd 143 SUPERFAMILY SSF56784 3 123 2.54E-8 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS10775 401f80f4c7b1cedeb47ee231bf725ecd 143 Pfam PF03031 NLI interacting factor-like phosphatase 5 133 1.1E-5 T 28-03-2018 IPR004274 FCP1 homology domain SmaCSM2_RS10775 401f80f4c7b1cedeb47ee231bf725ecd 143 Gene3D G3DSA:3.40.50.1000 1 143 3.3E-5 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 Gene3D G3DSA:3.40.50.300 131 187 6.2E-10 T 28-03-2018 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 Gene3D G3DSA:3.40.50.300 1 130 2.4E-40 T 28-03-2018 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 SUPERFAMILY SSF52540 1 186 2.79E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 Pfam PF00406 Adenylate kinase 5 162 4.4E-58 T 28-03-2018 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 Hamap MF_00235 Adenylate kinase [adk]. 1 186 46.354 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 TIGRFAM TIGR01351 adk: adenylate kinase 2 128 1.0E-50 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 PRINTS PR00094 Adenylate kinase signature 81 97 6.5E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 PRINTS PR00094 Adenylate kinase signature 150 164 6.5E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 PRINTS PR00094 Adenylate kinase signature 32 46 6.5E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 PRINTS PR00094 Adenylate kinase signature 133 148 6.5E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS17605 3877eae6c2db882333f27768b55398f1 187 PRINTS PR00094 Adenylate kinase signature 4 17 6.5E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 43 218 5.0E-62 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 Hamap MF_00013 Octanoyltransferase [lipB]. 21 222 38.147 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 Pfam PF03099 Biotin/lipoate A/B protein ligase family 79 175 5.8E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 SUPERFAMILY SSF55681 18 222 9.94E-71 T 28-03-2018 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 91 144 1.0E-19 T 28-03-2018 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 Gene3D G3DSA:3.30.930.10 16 220 1.0E-64 T 28-03-2018 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 87 102 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 SmaCSM2_RS18325 b2b0400af2cd46ed5e5518a52f10fc37 236 PIRSF PIRSF016262 18 234 2.7E-58 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 43 791 1.0E-228 T 28-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 SUPERFAMILY SSF56601 218 639 5.03E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 Gene3D G3DSA:3.40.710.10 251 618 9.2E-67 T 28-03-2018 SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 Gene3D G3DSA:1.10.3810.10 52 250 1.1E-57 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 Pfam PF00912 Transglycosylase 62 236 8.8E-48 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 704 789 7.3E-17 T 28-03-2018 IPR009647 Penicillin-binding, C-terminal SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 SUPERFAMILY SSF53955 49 266 8.44E-64 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS16165 32b39b25844c47c178175babcc6f19e3 793 Pfam PF00905 Penicillin binding protein transpeptidase domain 314 533 1.3E-12 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 Gene3D G3DSA:3.50.50.60 133 335 2.8E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 325 4.6E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 SUPERFAMILY SSF51905 7 335 2.92E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.4E-6 T 28-03-2018 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.4E-6 T 28-03-2018 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 1.4E-6 T 28-03-2018 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 Gene3D G3DSA:3.50.50.60 6 132 2.2E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.0E-10 T 28-03-2018 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.0E-10 T 28-03-2018 SmaCSM2_RS19150 36f50a89324272f9f557cfe05fca5ae1 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 2.0E-10 T 28-03-2018 SmaCSM2_RS11475 1f05ec254481a531a92e3cc8afbf39ec 337 Pfam PF13226 Domain of unknown function (DUF4034) 34 146 9.7E-5 T 28-03-2018 IPR025115 Domain of unknown function DUF4034 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 429 30.047 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 SUPERFAMILY SSF48557 22 400 1.57E-85 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 Gene3D G3DSA:1.10.40.30 376 430 7.5E-4 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 Gene3D G3DSA:1.20.200.10 110 375 2.0E-58 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 1.4E-13 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 1.4E-13 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 1.4E-13 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 3.7E-32 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 3.7E-32 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 3.7E-32 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 3.7E-32 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 3.7E-32 T 28-03-2018 SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 Pfam PF00206 Lyase 34 302 3.0E-46 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 Gene3D G3DSA:1.10.275.10 5 109 3.2E-25 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SmaCSM2_RS14600 f2b0bcf404a7cce7143a5685bc499e8e 431 TIGRFAM TIGR00838 argH: argininosuccinate lyase 24 390 4.3E-86 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 60 112 9.1E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 349 418 1.5E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Pfam PF07724 AAA domain (Cdc48 subfamily) 196 343 2.2E-39 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 SMART SM00382 56 346 2.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 SMART SM01086 349 448 7.8E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Gene3D G3DSA:1.10.8.60 349 445 5.0E-30 T 28-03-2018 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 11 457 4.9E-202 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 8 457 43.386 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 Gene3D G3DSA:3.40.50.300 8 346 1.6E-47 T 28-03-2018 SmaCSM2_RS18460 5b546260050bd335ab620c1e2590166b 457 SUPERFAMILY SSF52540 11 455 3.31E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1910 2015 7.32E-15 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 7.0E-11 T 28-03-2018 IPR024973 ESPR domain SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 193 269 1.31E-7 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 2139 2280 3.27E-21 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1680 1756 2.62E-10 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 814 884 3.27E-8 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 269 390 1.31E-24 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1182 1352 1.7E-31 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 730 803 6.0E-8 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:3.30.1300.30 2289 2393 8.0E-20 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 25 164 3.7E-23 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 496 575 4.8E-7 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 2033 2089 0.096 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 2202 2228 6.9E-6 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 547 571 2.8E-6 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 95 121 5.8E-6 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 643 669 3.3E-7 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1727 1753 7.8E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1210 1236 6.4E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1594 1620 2.8E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1566 1592 1.6E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 657 681 2.6E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 615 640 2.8E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 909 935 4.9E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1608 1632 2.7E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1419 1445 1.3E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1154 1180 2.1E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1484 1661 2.48E-33 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF54523 2271 2393 2.04E-14 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1053 1135 7.59E-10 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 403 491 3.27E-10 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1743 1891 1.06E-29 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 513 710 5.89E-29 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 368 409 2.9E-9 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1869 1899 1.9E-6 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1009 1049 8.2E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1330 1370 3.1E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 139 177 3.1E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 687 717 3.6E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2260 2297 2.4E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1638 1678 1.8E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2062 2092 0.22 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1989 2025 1.3E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 87 160 4.84E-20 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 730 811 4.32E-7 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1266 1360 4.9E-23 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 397 495 2.9E-10 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1043 1154 2.2E-15 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1898 2009 5.3E-19 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1155 1265 5.4E-21 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1667 1766 6.2E-13 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 579 719 1.1E-33 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 2119 2288 2.5E-24 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 276 396 1.8E-30 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1767 1897 1.7E-31 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 901 1041 5.2E-36 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1509 1666 5.1E-39 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 804 900 1.0E-14 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 866 1031 1.83E-35 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 SUPERFAMILY SSF101967 1386 1512 6.28E-15 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 1361 1479 9.2E-15 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:2.150.10.10 181 275 2.4E-7 T 28-03-2018 SmaCSM2_RS02950 729c59beaf9003adc0835f2df5fc6210 2393 Gene3D G3DSA:1.20.5.170 2010 2032 7.1E-9 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 Gene3D G3DSA:3.50.50.60 2 392 1.3E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 5.2E-8 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 186 201 5.2E-8 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 SUPERFAMILY SSF51905 314 457 1.25E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 SUPERFAMILY SSF51905 11 217 1.25E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 Pfam PF13450 NAD(P)-binding Rossmann-like domain 20 65 8.1E-8 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 SUPERFAMILY SSF54862 459 557 7.82E-27 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 SUPERFAMILY SSF54373 219 313 5.49E-37 T 28-03-2018 SmaCSM2_RS00835 ce4a0120b942a5d51aaf4437107a59cf 558 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 455 556 1.3E-49 T 28-03-2018 SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 SUPERFAMILY SSF52151 178 298 1.18E-43 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 SUPERFAMILY SSF52151 3 116 1.18E-43 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 Pfam PF00698 Acyl transferase domain 6 274 1.6E-15 T 28-03-2018 IPR014043 Acyl transferase SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 301 1.3E-11 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 TIGRFAM TIGR03131 malonate_mdcH: malonate decarboxylase, epsilon subunit 3 298 7.2E-92 T 28-03-2018 IPR017554 Malonate decarboxylase, McdH subunit SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 SUPERFAMILY SSF55048 124 180 7.72E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SmaCSM2_RS05675 f56557a2e0933ff4119f5965a7cce631 306 Gene3D G3DSA:3.40.366.10 1 297 1.9E-39 T 28-03-2018 SmaCSM2_RS19685 7c965f0733d702578b0eac45deb04afb 238 Gene3D G3DSA:3.40.50.1000 3 216 1.1E-13 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS19685 7c965f0733d702578b0eac45deb04afb 238 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 196 7.8E-27 T 28-03-2018 SmaCSM2_RS19685 7c965f0733d702578b0eac45deb04afb 238 SUPERFAMILY SSF56784 13 209 1.29E-19 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 SUPERFAMILY SSF100950 2 145 1.17E-46 T 28-03-2018 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 5 209 2.0E-69 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 SUPERFAMILY SSF75445 125 197 5.36E-23 T 28-03-2018 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 215 33.292 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 Gene3D G3DSA:3.40.50.1360 1 135 3.9E-44 T 28-03-2018 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 47 210 1.5E-58 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS17505 166fbf97a026e802e7f013d8d11cab03 215 Gene3D G3DSA:3.30.70.260 136 195 1.0E-23 T 28-03-2018 SmaCSM2_RS16320 1a4cc05f7d9acf7071afc7b5ba89ba7a 284 Pfam PF01551 Peptidase family M23 162 261 4.4E-20 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS16320 1a4cc05f7d9acf7071afc7b5ba89ba7a 284 Gene3D G3DSA:2.70.70.10 119 275 5.4E-25 T 28-03-2018 SmaCSM2_RS16320 1a4cc05f7d9acf7071afc7b5ba89ba7a 284 SUPERFAMILY SSF51261 162 262 1.31E-24 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 Pfam PF00570 HRDC domain 213 264 8.2E-5 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 SUPERFAMILY SSF47819 289 356 4.91E-12 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 Gene3D G3DSA:3.30.420.10 2 189 1.2E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 TIGRFAM TIGR01388 rnd: ribonuclease D 4 356 1.6E-114 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 SUPERFAMILY SSF53098 3 191 1.26E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 SUPERFAMILY SSF47819 191 282 2.46E-14 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 SMART SM00474 2 168 2.8E-29 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 Gene3D G3DSA:1.10.150.80 190 308 4.4E-11 T 28-03-2018 SmaCSM2_RS14800 fa5e88978e4e9a73a43450da150a95f3 359 Pfam PF01612 3'-5' exonuclease 4 167 2.3E-29 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 Gene3D G3DSA:3.40.190.10 92 179 6.3E-13 T 28-03-2018 SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 SUPERFAMILY SSF53850 89 298 1.21E-39 T 28-03-2018 SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 Gene3D G3DSA:1.10.10.10 1 84 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 Pfam PF03466 LysR substrate binding domain 88 295 1.2E-39 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 SUPERFAMILY SSF46785 3 87 2.04E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13605 cac480d9743c81c8cdbf5804e4b739ed 330 Gene3D G3DSA:3.40.190.10 180 266 1.7E-21 T 28-03-2018 SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 SMART SM00382 46 187 0.0017 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 1.8E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 Gene3D G3DSA:3.40.50.300 30 196 2.7E-24 T 28-03-2018 SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 Gene3D G3DSA:1.10.8.300 211 316 5.6E-23 T 28-03-2018 SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 PIRSF PIRSF002849 2 317 5.9E-121 T 28-03-2018 SmaCSM2_RS04760 486b1e948dc039dbe532c1777e442e87 317 SUPERFAMILY SSF52540 16 292 6.26E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09665 696ef8162ffdd7b2c3de7913a978241a 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 196 1.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS09665 696ef8162ffdd7b2c3de7913a978241a 231 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 229 1.4E-80 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 SmaCSM2_RS09665 696ef8162ffdd7b2c3de7913a978241a 231 Gene3D G3DSA:3.40.50.1000 79 231 4.0E-12 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09665 696ef8162ffdd7b2c3de7913a978241a 231 SUPERFAMILY SSF56784 1 227 2.16E-56 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09665 696ef8162ffdd7b2c3de7913a978241a 231 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 2 229 40.606 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 7 262 5.4E-143 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 SUPERFAMILY SSF56276 47 175 3.88E-24 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 Pfam PF02675 S-adenosylmethionine decarboxylase 43 170 1.0E-30 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 264 155.577 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 Gene3D G3DSA:3.60.90.10 37 190 8.2E-45 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 SmaCSM2_RS19670 709feaa7ef30a64f2bb4067024e0c31d 264 PIRSF PIRSF001356 2 264 5.1E-147 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 Gene3D G3DSA:3.40.190.10 181 270 3.6E-26 T 28-03-2018 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 SUPERFAMILY SSF46785 9 115 1.15E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 SUPERFAMILY SSF53850 94 298 2.76E-50 T 28-03-2018 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 8.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 Gene3D G3DSA:3.40.190.10 92 180 6.1E-26 T 28-03-2018 SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 Gene3D G3DSA:1.10.10.10 3 85 2.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11355 1c360a69dc11cd2008509f744e5ffd87 300 Pfam PF03466 LysR substrate binding domain 94 296 1.6E-52 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS05555 846692a7ea5ff1829559df3c91f3fffc 307 Gene3D G3DSA:3.40.50.1820 1 307 6.8E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05555 846692a7ea5ff1829559df3c91f3fffc 307 SUPERFAMILY SSF53474 3 141 5.12E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05555 846692a7ea5ff1829559df3c91f3fffc 307 SUPERFAMILY SSF53474 200 307 5.12E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05555 846692a7ea5ff1829559df3c91f3fffc 307 Pfam PF12146 Serine aminopeptidase, S33 53 130 6.3E-7 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS08720 e821d5c0ede0f36d6304f6ad9b361e1a 135 SUPERFAMILY SSF46785 6 131 7.37E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08720 e821d5c0ede0f36d6304f6ad9b361e1a 135 Gene3D G3DSA:1.10.10.10 2 89 3.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08720 e821d5c0ede0f36d6304f6ad9b361e1a 135 Pfam PF01475 Ferric uptake regulator family 9 129 3.8E-42 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 275 335 3.1E-15 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Pfam PF01627 Hpt domain 10 100 9.1E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:1.20.120.160 1 146 3.3E-37 T 28-03-2018 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 521 3.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:2.40.50.180 560 600 2.1E-9 T 28-03-2018 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Pfam PF01584 CheW-like domain 527 656 1.8E-27 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:2.30.30.40 523 559 0.056 T 28-03-2018 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:2.30.30.40 601 653 2.1E-20 T 28-03-2018 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SMART SM01231 274 337 1.3E-18 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SMART SM00260 514 653 9.6E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:3.30.565.10 339 522 1.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 Gene3D G3DSA:1.10.287.560 274 338 1.6E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 441 1.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 476 1.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 1.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 1.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SMART SM00387 382 522 2.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SUPERFAMILY SSF47384 275 338 4.32E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SUPERFAMILY SSF47226 5 129 5.36E-33 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SUPERFAMILY SSF50341 521 653 3.92E-32 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SMART SM00073 4 102 2.8E-29 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10040 78b3bc72ae3ce91aa2a10c4a45d9b21d 662 SUPERFAMILY SSF55874 339 520 4.45E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 Pfam PF00005 ABC transporter 25 173 2.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 SMART SM00382 34 228 4.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 Pfam PF02687 FtsX-like permease family 552 637 6.4E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 Gene3D G3DSA:3.40.50.300 1 261 4.9E-64 T 28-03-2018 SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 SUPERFAMILY SSF52540 5 225 1.46E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11680 2dc85da8b288c9876c109d485548a3f1 647 Pfam PF12704 MacB-like periplasmic core domain 275 488 6.4E-38 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 295 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 353 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 309 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SMART SM00304 82 136 6.6E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 246 353 1.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SUPERFAMILY SSF55874 191 354 2.36E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 Gene3D G3DSA:1.10.287.130 126 183 5.1E-9 T 28-03-2018 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 Gene3D G3DSA:3.30.565.10 184 355 2.3E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SUPERFAMILY SSF47384 120 202 3.34E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SMART SM00387 245 356 2.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SMART SM00388 137 201 1.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 201 9.0E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11700 1b9b1d5e2679564f0bc6120704afd843 358 SUPERFAMILY SSF158472 82 134 4.32E-5 T 28-03-2018 SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 Gene3D G3DSA:2.60.120.10 25 151 3.1E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 SMART SM00267 172 340 2.3E-40 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 SMART SM00100 25 140 2.1E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 SUPERFAMILY SSF51206 29 151 2.75E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 Pfam PF00027 Cyclic nucleotide-binding domain 45 128 1.8E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 SUPERFAMILY SSF55073 187 342 4.47E-40 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 89 107 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 Pfam PF00990 Diguanylate cyclase, GGDEF domain 184 335 1.6E-38 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 Gene3D G3DSA:3.30.70.270 180 346 4.3E-46 T 28-03-2018 SmaCSM2_RS01015 d02aa7b3dc0757c8d7280e44871b6334 346 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 183 337 1.6E-35 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 324 335 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 SUPERFAMILY SSF53335 147 441 3.68E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 439 2.6E-50 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Gene3D G3DSA:3.30.70.1170 179 236 3.4E-16 T 28-03-2018 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Gene3D G3DSA:1.10.287.730 152 177 5.3E-4 T 28-03-2018 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Gene3D G3DSA:1.10.940.10 15 151 2.1E-21 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 19 442 8.5E-107 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Pfam PF01029 NusB family 18 139 1.1E-19 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 267 1.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 424 441 1.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 242 1.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 325 337 1.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 375 391 1.6E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 SUPERFAMILY SSF48013 18 155 5.56E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS19045 20802d94975407296711534d4781bcf0 443 Gene3D G3DSA:3.40.50.150 237 443 5.0E-50 T 28-03-2018 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 Gene3D G3DSA:1.10.287.1060 417 504 0.09 T 28-03-2018 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 SMART SM00304 394 446 15.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 SMART SM00304 214 266 0.0041 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 170 3.5E-22 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 185 210 2.0E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 468 497 2.0E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 622 651 2.0E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 545 572 2.0E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 574 603 2.0E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 Gene3D G3DSA:1.20.120.30 25 188 4.5E-16 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 Gene3D G3DSA:1.10.287.950 505 698 3.0E-48 T 28-03-2018 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 SUPERFAMILY SSF58104 414 698 6.67E-72 T 28-03-2018 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 507 661 4.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 SUPERFAMILY SSF158472 214 263 2.62E-6 T 28-03-2018 SmaCSM2_RS10035 ac876ef1e004932943cd6f41875bf876 749 SMART SM00283 447 694 2.3E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS17810 aec6921f07f05df05d6004a2ae35edbf 215 SUPERFAMILY SSF53335 3 185 8.14E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS17810 aec6921f07f05df05d6004a2ae35edbf 215 Gene3D G3DSA:3.40.50.150 3 201 3.8E-35 T 28-03-2018 SmaCSM2_RS17810 aec6921f07f05df05d6004a2ae35edbf 215 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 177 3.5E-30 T 28-03-2018 SmaCSM2_RS17810 aec6921f07f05df05d6004a2ae35edbf 215 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 83 110 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 Gene3D G3DSA:1.10.260.40 4 55 8.4E-23 T 28-03-2018 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 7.0E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 SUPERFAMILY SSF53822 64 341 5.8E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 Gene3D G3DSA:3.40.50.2300 180 317 1.4E-44 T 28-03-2018 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 Pfam PF13377 Periplasmic binding protein-like domain 173 339 9.2E-37 T 28-03-2018 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 SUPERFAMILY SSF47413 2 61 9.38E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 Gene3D G3DSA:3.40.50.2300 56 179 5.8E-25 T 28-03-2018 SmaCSM2_RS18225 d74af0b622015822424b7cf10bf563f2 355 SMART SM00354 3 73 6.4E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS02610 c499b5c29329c42b72e37c618a608543 207 Gene3D G3DSA:2.40.160.40 87 205 0.0011 T 28-03-2018 SmaCSM2_RS02610 c499b5c29329c42b72e37c618a608543 207 Gene3D G3DSA:2.40.160.40 21 86 0.16 T 28-03-2018 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Gene3D G3DSA:3.30.450.20 180 292 1.1E-18 T 28-03-2018 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Pfam PF08448 PAS fold 196 310 8.8E-11 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Pfam PF08448 PAS fold 76 171 1.1E-6 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 SUPERFAMILY SSF55785 177 306 1.24E-15 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Pfam PF07536 HWE histidine kinase 322 402 1.2E-14 T 28-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Gene3D G3DSA:3.30.450.20 40 179 4.0E-10 T 28-03-2018 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 SUPERFAMILY SSF55785 52 163 8.57E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Gene3D G3DSA:3.30.450.20 293 329 0.0023 T 28-03-2018 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 185 315 9.8E-11 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 SMART SM00911 322 403 9.2E-17 T 28-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 SMART SM00086 267 309 1.2E-4 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS12020 20d95566ec39eb550281fac5aeb95063 527 Gene3D G3DSA:3.30.565.10 373 516 4.5E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 SUPERFAMILY SSF55347 151 314 1.82E-74 T 28-03-2018 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 Gene3D G3DSA:3.40.50.720 1 161 2.4E-79 T 28-03-2018 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 Gene3D G3DSA:3.30.360.10 162 316 9.4E-77 T 28-03-2018 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 104 6.3E-38 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 6.1E-47 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 6.1E-47 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 6.1E-47 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 6.1E-47 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 6.1E-47 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 PIRSF PIRSF000149 1 334 5.7E-129 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 4.6E-132 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 SUPERFAMILY SSF51735 3 168 3.32E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 7.3E-65 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17175 cbfb394891e75be1088e8f7e43d5563b 334 SMART SM00846 3 152 3.4E-95 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS04715 2d8da5a48e3aa61922aec44e08a41dc3 473 SUPERFAMILY SSF56349 146 435 5.59E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS04715 2d8da5a48e3aa61922aec44e08a41dc3 473 Pfam PF00589 Phage integrase family 280 424 2.0E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS04715 2d8da5a48e3aa61922aec44e08a41dc3 473 Gene3D G3DSA:1.10.150.130 140 255 4.5E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS04715 2d8da5a48e3aa61922aec44e08a41dc3 473 Gene3D G3DSA:1.10.443.10 256 441 3.9E-18 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 SUPERFAMILY SSF53822 75 346 9.82E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 SMART SM00354 15 85 1.3E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Gene3D G3DSA:3.40.50.2300 72 181 3.5E-29 T 28-03-2018 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Gene3D G3DSA:1.10.10.60 10 30 8.4E-4 T 28-03-2018 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 6.2E-10 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Gene3D G3DSA:3.40.50.2300 182 347 2.9E-47 T 28-03-2018 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Pfam PF13377 Periplasmic binding protein-like domain 183 344 1.3E-38 T 28-03-2018 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 Gene3D G3DSA:1.10.260.40 31 71 1.1E-15 T 28-03-2018 SmaCSM2_RS09640 c59dc81b375a2d43e37a0431c6bdda7e 349 SUPERFAMILY SSF47413 15 73 1.22E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 339 3.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SUPERFAMILY SSF55785 36 130 4.19E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 500 2.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Gene3D G3DSA:1.10.287.130 272 337 5.4E-15 T 28-03-2018 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SUPERFAMILY SSF55874 331 503 4.85E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00387 388 501 5.1E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Gene3D G3DSA:3.30.450.20 7 123 4.2E-13 T 28-03-2018 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Pfam PF00072 Response regulator receiver domain 533 650 3.8E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00388 276 342 2.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Gene3D G3DSA:3.30.450.20 124 271 1.3E-34 T 28-03-2018 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00086 207 249 0.001 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00091 135 201 3.0E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00091 9 83 170.0 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SUPERFAMILY SSF52172 529 652 4.27E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Pfam PF13188 PAS domain 11 75 4.6E-4 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SUPERFAMILY SSF47384 261 339 1.37E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SMART SM00448 531 649 5.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 453 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 4.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Gene3D G3DSA:3.40.50.2300 524 659 1.9E-31 T 28-03-2018 SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 254 1.5E-17 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Gene3D G3DSA:3.30.565.10 346 509 9.0E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 SUPERFAMILY SSF55785 120 247 7.5E-25 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02440 6ea138a77d53fe92df590779df5e0883 662 Pfam PF08447 PAS fold 159 241 6.5E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS17525 05611ba308612f2abb23df045c62932c 208 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 11 200 5.1E-56 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS17525 05611ba308612f2abb23df045c62932c 208 Gene3D G3DSA:3.20.20.70 2 207 5.2E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS17525 05611ba308612f2abb23df045c62932c 208 Pfam PF02581 Thiamine monophosphate synthase 11 190 5.2E-52 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS17525 05611ba308612f2abb23df045c62932c 208 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 9 208 24.135 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS17525 05611ba308612f2abb23df045c62932c 208 SUPERFAMILY SSF51391 8 204 2.62E-58 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 SUPERFAMILY SSF46785 1 85 2.36E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.7E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 SUPERFAMILY SSF53850 87 293 4.5E-34 T 28-03-2018 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 Gene3D G3DSA:3.40.190.10 88 175 5.4E-18 T 28-03-2018 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 Pfam PF03466 LysR substrate binding domain 87 293 7.2E-35 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 Gene3D G3DSA:3.40.190.10 176 268 2.0E-18 T 28-03-2018 SmaCSM2_RS07420 c56be057eb714a57b837ace470519c8a 296 Gene3D G3DSA:1.10.10.10 1 83 3.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 8.0E-4 T 28-03-2018 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 1.3E-52 T 28-03-2018 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.5E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 245 6.0E-98 T 28-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 SUPERFAMILY SSF51735 4 245 2.94E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 Gene3D G3DSA:3.40.50.720 47 246 9.7E-58 T 28-03-2018 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 Gene3D G3DSA:3.40.50.720 1 46 6.3E-4 T 28-03-2018 SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17915 d88b085051bf5db48373f2b937d4e3dd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS03560 9bc9b409498bbd30508188ab3c088e47 326 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 319 33.775 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SmaCSM2_RS03560 9bc9b409498bbd30508188ab3c088e47 326 Gene3D G3DSA:3.40.718.10 1 324 2.1E-117 T 28-03-2018 SmaCSM2_RS03560 9bc9b409498bbd30508188ab3c088e47 326 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 319 1.2E-113 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SmaCSM2_RS03560 9bc9b409498bbd30508188ab3c088e47 326 SUPERFAMILY SSF53659 3 322 2.27E-98 T 28-03-2018 SmaCSM2_RS03560 9bc9b409498bbd30508188ab3c088e47 326 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 30 314 7.4E-97 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SmaCSM2_RS03505 23f3d5f1d891b7bae5da0ca11af7f49c 386 Gene3D G3DSA:1.20.1250.20 193 382 7.0E-14 T 28-03-2018 SmaCSM2_RS03505 23f3d5f1d891b7bae5da0ca11af7f49c 386 SUPERFAMILY SSF103473 4 381 2.88E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS03505 23f3d5f1d891b7bae5da0ca11af7f49c 386 Gene3D G3DSA:1.20.1250.20 2 192 5.6E-24 T 28-03-2018 SmaCSM2_RS03505 23f3d5f1d891b7bae5da0ca11af7f49c 386 Pfam PF07690 Major Facilitator Superfamily 10 329 1.0E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Pfam PF13377 Periplasmic binding protein-like domain 181 340 2.4E-39 T 28-03-2018 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Gene3D G3DSA:1.10.10.10 2 21 0.0068 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 SMART SM00354 6 76 1.5E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Gene3D G3DSA:3.40.50.2300 181 343 1.5E-49 T 28-03-2018 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 51 1.0E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 SUPERFAMILY SSF53822 80 328 2.16E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Gene3D G3DSA:1.10.260.40 22 62 2.7E-19 T 28-03-2018 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 SUPERFAMILY SSF47413 6 62 1.44E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS05460 ca82d0e37e0dd5c255d9d17d2be8bd9e 343 Gene3D G3DSA:3.40.50.2300 63 180 1.4E-18 T 28-03-2018 SmaCSM2_RS15635 0b868c8c3c32c47a9e01430c827bf435 199 Pfam PF06197 Protein of unknown function (DUF998) 13 192 4.3E-12 T 28-03-2018 IPR009339 Protein of unknown function DUF998 SmaCSM2_RS16505 f4b66faccf0c405070c44846e9fe98b7 294 SUPERFAMILY SSF74653 181 290 2.85E-19 T 28-03-2018 SmaCSM2_RS16505 f4b66faccf0c405070c44846e9fe98b7 294 SUPERFAMILY SSF74653 136 143 2.85E-19 T 28-03-2018 SmaCSM2_RS16505 f4b66faccf0c405070c44846e9fe98b7 294 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 207 274 2.3E-17 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS16505 f4b66faccf0c405070c44846e9fe98b7 294 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 209 284 8.2E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS16505 f4b66faccf0c405070c44846e9fe98b7 294 Gene3D G3DSA:3.30.1150.10 71 294 8.6E-23 T 28-03-2018 SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 SUPERFAMILY SSF52266 32 237 7.02E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 SUPERFAMILY SSF52266 277 306 7.02E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 SMART SM00869 340 601 1.3E-28 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 33 44 - T 28-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 PIRSF PIRSF037375 3 611 8.0E-172 T 28-03-2018 IPR017186 Lipase, autotransporter EstA SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 Gene3D G3DSA:3.40.50.1110 18 303 1.7E-58 T 28-03-2018 SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 SUPERFAMILY SSF103515 336 580 5.36E-30 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 Pfam PF03797 Autotransporter beta-domain 348 579 6.3E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 34 299 3.9E-10 T 28-03-2018 IPR001087 GDSL lipase/esterase GO:0016788 SmaCSM2_RS17020 329e64cf8d3508b4ae3f883e07595fcd 611 Gene3D G3DSA:2.40.128.130 304 600 5.2E-30 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 Pfam PF13481 AAA domain 87 225 8.4E-15 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 SUPERFAMILY SSF52540 72 293 3.07E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 SMART SM00382 94 247 5.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 42.747 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 455 2.7E-192 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 Gene3D G3DSA:3.40.50.300 64 246 1.4E-16 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 Gene3D G3DSA:3.30.230.10 247 458 2.1E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 86 114 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 10 34 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 216 244 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 177 201 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 325 348 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 127 144 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 PRINTS PR01874 DNA repair protein radA signature 251 277 8.8E-93 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 351 433 3.0E-10 T 28-03-2018 SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 SUPERFAMILY SSF54211 258 272 2.88E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS06025 a0ff8b85cf6d0d32819c86eec41fdab0 458 SUPERFAMILY SSF54211 306 457 2.88E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS02365 28ca0ce43dac918c875780069ed9d2e2 262 PIRSF PIRSF006157 1 261 1.3E-84 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 SmaCSM2_RS02365 28ca0ce43dac918c875780069ed9d2e2 262 SUPERFAMILY SSF53213 3 260 1.06E-88 T 28-03-2018 SmaCSM2_RS02365 28ca0ce43dac918c875780069ed9d2e2 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 6 235 5.1E-45 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SmaCSM2_RS02365 28ca0ce43dac918c875780069ed9d2e2 262 Gene3D G3DSA:3.40.830.10 1 260 4.6E-87 T 28-03-2018 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 SUPERFAMILY SSF46626 331 432 9.76E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 SUPERFAMILY SSF46626 192 309 2.28E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Gene3D G3DSA:1.10.760.10 319 440 7.1E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 SUPERFAMILY SSF46626 38 169 7.87E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Gene3D G3DSA:1.10.760.10 12 159 2.3E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Pfam PF00034 Cytochrome c 192 301 5.2E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Pfam PF00034 Cytochrome c 46 143 1.9E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Pfam PF00034 Cytochrome c 331 414 2.7E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 Gene3D G3DSA:1.10.760.10 172 318 3.4E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08220 5d6e3ad68e9dd82879ae5b362716b9e4 448 PIRSF PIRSF000018 12 446 5.3E-147 T 28-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 434 1.2E-167 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Gene3D G3DSA:3.30.300.20 358 435 1.0E-25 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 356 434 8.1E-23 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Gene3D G3DSA:1.20.120.430 3 69 3.9E-14 T 28-03-2018 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 PIRSF PIRSF006485 1 442 6.1E-170 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Gene3D G3DSA:1.20.120.430 70 246 2.7E-50 T 28-03-2018 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Gene3D G3DSA:1.20.120.430 247 357 1.4E-13 T 28-03-2018 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 1.4E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.4E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 SUPERFAMILY SSF52540 1 173 1.27E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Pfam PF01926 50S ribosome-binding GTPase 5 120 6.6E-27 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Pfam PF01926 50S ribosome-binding GTPase 180 298 8.3E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 159 1.0E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 344 8.5E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 SUPERFAMILY SSF52540 138 440 1.48E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09070 1d70886fcb1c779a5da5c1a12c4843d0 465 Hamap MF_00195 GTPase Der [der]. 2 437 37.122 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SmaCSM2_RS17045 c7ab052aeba395398db4156c11229894 111 Pfam PF00355 Rieske [2Fe-2S] domain 28 93 2.2E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS17045 c7ab052aeba395398db4156c11229894 111 SUPERFAMILY SSF50022 23 110 8.25E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS17045 c7ab052aeba395398db4156c11229894 111 Gene3D G3DSA:2.102.10.10 2 111 6.2E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 Hamap MF_00456 Glutamate 5-kinase [proB]. 21 273 34.458 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 Pfam PF01472 PUA domain 291 368 1.6E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 Pfam PF00696 Amino acid kinase family 22 249 1.9E-35 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 PRINTS PR00474 Glutamate 5-kinase family signature 130 151 1.1E-38 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 PRINTS PR00474 Glutamate 5-kinase family signature 223 243 1.1E-38 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 PRINTS PR00474 Glutamate 5-kinase family signature 162 189 1.1E-38 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 PRINTS PR00474 Glutamate 5-kinase family signature 58 72 1.1E-38 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 SUPERFAMILY SSF53633 21 270 1.11E-58 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 TIGRFAM TIGR01027 proB: glutamate 5-kinase 22 383 3.4E-121 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 PIRSF PIRSF000729 18 385 1.5E-129 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 Gene3D G3DSA:2.30.130.10 289 384 8.8E-27 T 28-03-2018 IPR002478 PUA domain GO:0003723 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 Gene3D G3DSA:3.40.1160.10 11 279 1.2E-51 T 28-03-2018 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 SUPERFAMILY SSF88697 291 384 2.21E-21 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 SMART SM00359 291 377 1.1E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 SmaCSM2_RS14590 3c9ac71c14823fc1cd811b9c52239f51 385 ProSitePatterns PS00902 Glutamate 5-kinase signature. 221 238 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 Gene3D G3DSA:1.20.1530.10 16 432 3.1E-119 T 28-03-2018 IPR023171 Na/H antiporter domain SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 SUPERFAMILY SSF52833 447 608 5.1E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 Pfam PF06965 Na+/H+ antiporter 1 20 425 1.3E-118 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 Pfam PF13462 Thioredoxin 453 608 3.5E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 18 432 18.979 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 22 424 3.5E-85 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS07500 fc7b338c8b8c982fac06ba88aa791819 621 Gene3D G3DSA:3.40.30.10 448 613 5.1E-33 T 28-03-2018 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 SUPERFAMILY SSF54747 3 72 5.63E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 3.4E-23 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.5E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 SUPERFAMILY SSF46906 68 141 3.01E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 SMART SM00649 9 141 3.8E-82 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 Gene3D G3DSA:3.30.1550.10 3 72 1.9E-34 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 Gene3D G3DSA:1.10.10.250 73 141 4.9E-23 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.924 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.2E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SmaCSM2_RS03930 53ec6f4257bf16ff203df2800f928d7f 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 72 2.0E-14 T 28-03-2018 SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 SUPERFAMILY SSF49265 646 725 6.89E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Gene3D G3DSA:2.60.40.10 631 830 6.8E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Pfam PF09327 Domain of unknown function (DUF1983) 1007 1088 1.8E-27 T 28-03-2018 IPR015406 Domain of unknown function DUF1983 SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Pfam PF13550 Putative phage tail protein 354 513 3.3E-20 T 28-03-2018 IPR032876 Tip attachment protein J SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Gene3D G3DSA:1.20.1270.70 974 1031 8.9E-4 T 28-03-2018 SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Gene3D G3DSA:1.20.1270.70 911 973 0.052 T 28-03-2018 SmaCSM2_RS01275 79eae2c1566f28335b923715353289c2 1162 Gene3D G3DSA:2.10.10.20 863 908 3.3E-5 T 28-03-2018 SmaCSM2_RS21415 9eefa528b60ca8f3adb229a51925ba69 511 Gene3D G3DSA:1.10.287.110 4 326 1.6E-7 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS21415 9eefa528b60ca8f3adb229a51925ba69 511 SUPERFAMILY SSF46565 6 48 2.49E-5 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 9.5E-14 T 28-03-2018 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 9.5E-14 T 28-03-2018 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 9.5E-14 T 28-03-2018 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 9.5E-14 T 28-03-2018 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 SUPERFAMILY SSF51905 1 289 1.59E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 Gene3D G3DSA:3.50.50.60 132 295 1.0E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 278 3.6E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 9.7E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 136 9.7E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 9.7E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 276 9.7E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 9.7E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20995 8204cc3d4d251fba1146e0080d268fe5 301 Gene3D G3DSA:3.50.50.60 1 131 3.8E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS11705 97a65228e9b6137d247fd19dc24ed34f 308 SUPERFAMILY SSF90123 23 296 5.1E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS11705 97a65228e9b6137d247fd19dc24ed34f 308 Gene3D G3DSA:1.20.1560.10 202 296 1.2E-4 T 28-03-2018 SmaCSM2_RS11705 97a65228e9b6137d247fd19dc24ed34f 308 Pfam PF13748 ABC transporter transmembrane region 23 259 3.7E-96 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS11705 97a65228e9b6137d247fd19dc24ed34f 308 Gene3D G3DSA:1.20.1560.10 16 201 4.8E-7 T 28-03-2018 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 1.7E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 SMART SM00418 8 89 4.7E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 Gene3D G3DSA:1.10.10.10 1 96 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 SUPERFAMILY SSF46785 1 81 1.04E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 Gene3D G3DSA:3.40.50.150 98 295 1.7E-33 T 28-03-2018 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 SUPERFAMILY SSF53335 127 293 2.59E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14020 0f96694f41d9360639f7053943efcf91 309 Pfam PF08241 Methyltransferase domain 152 245 1.8E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 SMART SM01134 77 237 1.3E-45 T 28-03-2018 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 Gene3D G3DSA:1.10.10.10 6 78 3.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 SUPERFAMILY SSF100950 83 238 1.15E-21 T 28-03-2018 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 SMART SM00420 12 64 6.6E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 Pfam PF08220 DeoR-like helix-turn-helix domain 12 65 1.7E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 Pfam PF00455 DeoR C terminal sensor domain 82 233 9.6E-36 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 Gene3D G3DSA:3.40.50.1360 79 243 5.0E-28 T 28-03-2018 SmaCSM2_RS04880 da25f82c8efbbeee9b8784856a6da1e3 258 SUPERFAMILY SSF46785 11 67 3.05E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 SUPERFAMILY SSF47336 2 77 7.85E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 2.4E-36 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.69 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 Gene3D G3DSA:1.10.1200.10 1 79 3.9E-28 T 28-03-2018 SmaCSM2_RS04805 aaebb1d43b9ea0a9a3a27f66970dd9b1 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.8E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS15910 9975f93e1cc0b0bc3a79911141c34ceb 231 Pfam PF01323 DSBA-like thioredoxin domain 2 205 1.0E-38 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SmaCSM2_RS15910 9975f93e1cc0b0bc3a79911141c34ceb 231 Gene3D G3DSA:3.40.30.10 1 216 6.0E-55 T 28-03-2018 SmaCSM2_RS15910 9975f93e1cc0b0bc3a79911141c34ceb 231 SUPERFAMILY SSF52833 1 210 9.68E-50 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 502 3.6E-208 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 504 45.538 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 SUPERFAMILY SSF48557 2 498 3.06E-188 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 Gene3D G3DSA:1.10.275.10 3 197 3.7E-67 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 Gene3D G3DSA:1.20.200.10 199 510 1.5E-121 T 28-03-2018 SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 Pfam PF00221 Aromatic amino acid lyase 13 470 3.8E-182 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SmaCSM2_RS13695 bcc4d325d7b3ba4c1facde8e2e35bbf8 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Gene3D G3DSA:3.40.1190.20 224 491 8.0E-52 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 31 209 6.1E-38 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 PIRSF PIRSF017184 6 493 4.6E-124 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 224 493 23.241 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 SUPERFAMILY SSF53613 226 484 7.32E-72 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 314 324 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 SUPERFAMILY SSF64153 7 246 3.27E-52 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Pfam PF01256 Carbohydrate kinase 247 481 3.1E-61 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Gene3D G3DSA:3.40.50.10260 2 223 2.3E-53 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 209 20.645 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 222 487 1.1E-72 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SmaCSM2_RS14770 6d04fe9d9ec8b9080fae5d60ba33d9d2 494 Pfam PF03853 YjeF-related protein N-terminus 31 187 3.0E-39 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SmaCSM2_RS13980 cda419b4878dd92b73a7aade33bdefab 257 Gene3D G3DSA:3.40.50.10330 6 113 5.5E-14 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SmaCSM2_RS13980 cda419b4878dd92b73a7aade33bdefab 257 Gene3D G3DSA:2.60.200.30 114 232 5.8E-22 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SmaCSM2_RS13980 cda419b4878dd92b73a7aade33bdefab 257 Hamap MF_00361 NAD kinase [nadK]. 5 257 20.396 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SmaCSM2_RS13980 cda419b4878dd92b73a7aade33bdefab 257 Pfam PF01513 ATP-NAD kinase 26 221 9.0E-13 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SmaCSM2_RS13980 cda419b4878dd92b73a7aade33bdefab 257 SUPERFAMILY SSF111331 25 244 1.31E-51 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SmaCSM2_RS16070 c580e82760fd2a1aff6a94db3fda9027 136 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 128 1.8E-25 T 28-03-2018 IPR028973 PhnB-like SmaCSM2_RS16070 c580e82760fd2a1aff6a94db3fda9027 136 PIRSF PIRSF021700 1 135 3.3E-27 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase SmaCSM2_RS16070 c580e82760fd2a1aff6a94db3fda9027 136 Gene3D G3DSA:3.10.180.10 8 134 1.8E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS16070 c580e82760fd2a1aff6a94db3fda9027 136 SUPERFAMILY SSF54593 5 133 5.63E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 Gene3D G3DSA:3.10.310.10 200 372 9.4E-71 T 28-03-2018 SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 SUPERFAMILY SSF54506 2 181 2.2E-69 T 28-03-2018 SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 4 392 2.5E-225 T 28-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 SUPERFAMILY SSF54506 188 391 2.82E-75 T 28-03-2018 SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 Gene3D G3DSA:3.10.310.10 5 199 1.0E-84 T 28-03-2018 SmaCSM2_RS16180 b58afd3ddcfdfdc63f1218a3fdc29114 392 Pfam PF04303 PrpF protein 6 390 4.4E-174 T 28-03-2018 IPR007400 PrpF protein SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 SUPERFAMILY SSF54373 270 356 1.96E-13 T 28-03-2018 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 Pfam PF01266 FAD dependent oxidoreductase 7 397 2.5E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 Gene3D G3DSA:3.50.50.60 2 416 7.3E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 SUPERFAMILY SSF51905 119 270 4.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 SUPERFAMILY SSF51905 358 415 4.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 SUPERFAMILY SSF51905 7 58 4.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 410 416 7.2E-5 T 28-03-2018 SmaCSM2_RS15480 6db4681952c578a436eb7f6e2dbf8ba4 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 7.2E-5 T 28-03-2018 SmaCSM2_RS01855 a0bd9bdd6307e0213743f276f3dbff32 147 Pfam PF09424 Yqey-like protein 4 146 2.1E-56 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial SmaCSM2_RS01855 a0bd9bdd6307e0213743f276f3dbff32 147 Gene3D G3DSA:1.10.10.410 91 147 8.5E-20 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SmaCSM2_RS01855 a0bd9bdd6307e0213743f276f3dbff32 147 Gene3D G3DSA:1.10.1510.10 1 90 5.3E-32 T 28-03-2018 SmaCSM2_RS01855 a0bd9bdd6307e0213743f276f3dbff32 147 SUPERFAMILY SSF89095 1 146 6.8E-45 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 Gene3D G3DSA:3.40.50.2300 1 137 3.1E-34 T 28-03-2018 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 Gene3D G3DSA:1.10.10.10 138 200 3.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 2.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 2.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 2.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 SMART SM00448 2 115 1.7E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 SMART SM00421 137 194 1.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 SUPERFAMILY SSF52172 1 128 1.31E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 Pfam PF00072 Response regulator receiver domain 4 115 5.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 3.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01480 90842f22ccd957bf5f47f98912a134d9 200 SUPERFAMILY SSF46894 125 200 2.48E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS18835 6345c44707bf53f345d18c7b78c71e3a 128 ProDom PD031864 YIGF SIMILAR ESCHERICHIA COLI MEMBRANE XCC4223 XAC4357 XAC2195 10 122 3.0E-20 T 28-03-2018 SmaCSM2_RS18835 6345c44707bf53f345d18c7b78c71e3a 128 Pfam PF10947 Protein of unknown function (DUF2628) 14 113 2.9E-16 T 28-03-2018 IPR024399 Protein of unknown function DUF2628 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 SUPERFAMILY SSF52540 347 589 9.63E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 Gene3D G3DSA:1.20.1560.10 3 340 8.5E-56 T 28-03-2018 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 SMART SM00382 379 565 2.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 Pfam PF00005 ABC transporter 371 518 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 Pfam PF00664 ABC transporter transmembrane region 43 311 1.7E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 SUPERFAMILY SSF90123 26 340 1.23E-62 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS18595 1719ab7cdbb55a8cc18d4b226560a93c 606 Gene3D G3DSA:3.40.50.300 341 595 1.3E-72 T 28-03-2018 SmaCSM2_RS21105 c2bc9ace22acf210223111286d7d8bbe 516 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 146 162 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SmaCSM2_RS21105 c2bc9ace22acf210223111286d7d8bbe 516 SUPERFAMILY SSF48557 8 511 3.37E-164 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SmaCSM2_RS21105 c2bc9ace22acf210223111286d7d8bbe 516 Pfam PF00221 Aromatic amino acid lyase 16 466 3.4E-158 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SmaCSM2_RS21105 c2bc9ace22acf210223111286d7d8bbe 516 Gene3D G3DSA:1.10.275.10 3 204 2.6E-63 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SmaCSM2_RS21105 c2bc9ace22acf210223111286d7d8bbe 516 Gene3D G3DSA:1.20.200.10 205 514 4.6E-97 T 28-03-2018 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 388 6.5E-101 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 Gene3D G3DSA:3.50.50.60 1 392 8.8E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 Pfam PF01494 FAD binding domain 5 347 1.5E-30 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 6 388 4.0E-120 T 28-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 3.2E-17 T 28-03-2018 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 3.2E-17 T 28-03-2018 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.2E-17 T 28-03-2018 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 3.2E-17 T 28-03-2018 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 SUPERFAMILY SSF51905 269 375 2.68E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03590 dcf7dc42f8c190cc4efe16b3a9e49290 402 SUPERFAMILY SSF51905 5 179 2.68E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 70 2.2E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 190 2.6E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 SUPERFAMILY SSF52833 1 78 4.94E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 SUPERFAMILY SSF47616 73 197 6.54E-29 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 Gene3D G3DSA:1.20.1050.10 94 196 7.1E-24 T 28-03-2018 SmaCSM2_RS21675 f58bdfa3f7be48a188e58398a08d7453 201 Gene3D G3DSA:3.40.30.10 1 93 3.0E-26 T 28-03-2018 SmaCSM2_RS13305 0527c82a387fb83d0922027dc0421dde 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 344 5.6E-83 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS13305 0527c82a387fb83d0922027dc0421dde 371 Gene3D G3DSA:3.20.20.70 1 371 2.1E-124 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS13305 0527c82a387fb83d0922027dc0421dde 371 SUPERFAMILY SSF51395 2 367 1.34E-122 T 28-03-2018 SmaCSM2_RS05650 48f436b1218c5dafd0a143a0740b6d4c 419 Pfam PF00083 Sugar (and other) transporter 12 212 7.2E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS05650 48f436b1218c5dafd0a143a0740b6d4c 419 SUPERFAMILY SSF103473 5 414 7.59E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS05650 48f436b1218c5dafd0a143a0740b6d4c 419 Pfam PF07690 Major Facilitator Superfamily 264 416 7.8E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS05650 48f436b1218c5dafd0a143a0740b6d4c 419 Gene3D G3DSA:1.20.1250.20 1 211 7.2E-30 T 28-03-2018 SmaCSM2_RS05650 48f436b1218c5dafd0a143a0740b6d4c 419 Gene3D G3DSA:1.20.1250.20 212 417 7.3E-23 T 28-03-2018 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Gene3D G3DSA:2.40.30.20 5 84 3.0E-30 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Gene3D G3DSA:1.20.150.20 386 512 1.5E-45 T 28-03-2018 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 368 377 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 5 512 1.9E-246 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 377 1.0E-71 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 SUPERFAMILY SSF47917 385 512 1.2E-45 T 28-03-2018 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Gene3D G3DSA:3.40.50.300 85 377 2.8E-113 T 28-03-2018 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 SUPERFAMILY SSF52540 98 383 2.66E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 94 5.7E-12 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 SUPERFAMILY SSF50615 12 96 1.84E-26 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 384 509 8.3E-44 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18700 9b48103f607c479878d7b9bd28f134e8 515 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 3 514 49.536 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS02765 b04823717193898d9f278976150892c6 248 SUPERFAMILY SSF52402 1 244 4.42E-79 T 28-03-2018 SmaCSM2_RS02765 b04823717193898d9f278976150892c6 248 PIRSF PIRSF000090 1 248 7.8E-83 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 SmaCSM2_RS02765 b04823717193898d9f278976150892c6 248 SMART SM00893 23 211 1.8E-57 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SmaCSM2_RS02765 b04823717193898d9f278976150892c6 248 Gene3D G3DSA:3.40.50.620 1 248 2.1E-79 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS02765 b04823717193898d9f278976150892c6 248 Pfam PF01012 Electron transfer flavoprotein domain 26 206 1.2E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SmaCSM2_RS15290 da6e82f02211852ddc3d9007bf34f552 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 112 2.2E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS15290 da6e82f02211852ddc3d9007bf34f552 120 SUPERFAMILY SSF54593 5 118 2.15E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS15290 da6e82f02211852ddc3d9007bf34f552 120 Gene3D G3DSA:3.10.180.10 1 119 5.7E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 SMART SM00387 483 596 1.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Pfam PF08448 PAS fold 233 340 2.6E-9 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Pfam PF05227 CHASE3 domain 43 174 2.2E-24 T 28-03-2018 IPR007891 CHASE3 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Gene3D G3DSA:3.30.565.10 430 595 2.6E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 537 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 574 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 593 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Gene3D G3DSA:3.30.450.20 199 361 2.2E-18 T 28-03-2018 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 483 595 7.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 SUPERFAMILY SSF55874 423 594 1.44E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 222 339 7.5E-10 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 432 8.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 SUPERFAMILY SSF47384 351 432 2.55E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 SMART SM00388 366 434 4.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 Gene3D G3DSA:1.10.287.130 362 429 1.8E-14 T 28-03-2018 SmaCSM2_RS18285 5e974ba6bf748d6e5d2d45d76656298c 605 SUPERFAMILY SSF55785 208 337 2.79E-16 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS01195 50312fdf2bfcdb44dbd7b22fa42c1dc1 391 Pfam PF16113 Enoyl-CoA hydratase/isomerase 25 367 2.2E-107 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SmaCSM2_RS01195 50312fdf2bfcdb44dbd7b22fa42c1dc1 391 SUPERFAMILY SSF52096 24 213 1.49E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01195 50312fdf2bfcdb44dbd7b22fa42c1dc1 391 SUPERFAMILY SSF52096 282 352 1.49E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01195 50312fdf2bfcdb44dbd7b22fa42c1dc1 391 Gene3D G3DSA:3.90.226.10 2 361 1.9E-73 T 28-03-2018 SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 Pfam PF04055 Radical SAM superfamily 127 246 1.3E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 SUPERFAMILY SSF102114 117 335 2.75E-19 T 28-03-2018 SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 Pfam PF13394 4Fe-4S single cluster domain 126 196 6.4E-6 T 28-03-2018 SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 Gene3D G3DSA:3.20.20.70 109 326 3.7E-15 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 TIGRFAM TIGR00238 TIGR00238: KamA family protein 26 339 2.6E-91 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 PIRSF PIRSF004911 9 346 2.0E-103 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase SmaCSM2_RS14700 f0c1e2cffc26ae04b8cd163ba49e5031 346 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 26 345 4.0E-134 T 28-03-2018 IPR022462 Lysine-2,3-aminomutase-like SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 33.724 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 189 5.8E-58 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 Gene3D G3DSA:3.40.50.1470 2 192 3.1E-64 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 8.7E-51 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS03845 b6b436f5c9800955675940a8107b97c8 192 SUPERFAMILY SSF53178 5 189 1.28E-63 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 SUPERFAMILY SSF101898 69 346 8.89E-43 T 28-03-2018 SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 Gene3D G3DSA:2.120.10.30 215 348 1.1E-11 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 Gene3D G3DSA:2.120.10.30 118 214 2.2E-17 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 Pfam PF01436 NHL repeat 123 148 5.7E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 Gene3D G3DSA:2.120.10.30 50 117 0.0024 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS02245 aa9d14e089563221dabb9ccc071514ff 693 Gene3D G3DSA:2.70.70.10 360 519 7.2E-7 T 28-03-2018 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 4.2E-13 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 Gene3D G3DSA:3.40.1030.10 73 343 5.7E-107 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 SUPERFAMILY SSF47648 4 71 1.57E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 Gene3D G3DSA:1.20.970.10 1 72 7.8E-17 T 28-03-2018 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 Pfam PF00591 Glycosyl transferase family, a/b domain 77 327 6.6E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 SUPERFAMILY SSF52418 78 339 5.1E-96 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 336 1.0E-126 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SmaCSM2_RS19695 466329352703856738b7c9e3c0c560da 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 37.211 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SmaCSM2_RS17690 dd424455ea844cb3905efb53b439fae9 178 Pfam PF00719 Inorganic pyrophosphatase 18 172 5.9E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS17690 dd424455ea844cb3905efb53b439fae9 178 SUPERFAMILY SSF50324 6 173 2.22E-66 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS17690 dd424455ea844cb3905efb53b439fae9 178 Gene3D G3DSA:3.90.80.10 3 177 3.1E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS17690 dd424455ea844cb3905efb53b439fae9 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.597 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08235 bd8e2011cbd62c94695a4033a50092fa 231 Pfam PF12697 Alpha/beta hydrolase family 7 220 3.9E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS08235 bd8e2011cbd62c94695a4033a50092fa 231 SUPERFAMILY SSF53474 2 224 4.12E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08235 bd8e2011cbd62c94695a4033a50092fa 231 Gene3D G3DSA:3.40.50.1820 2 228 5.1E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 245 4.7E-99 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 Gene3D G3DSA:3.40.50.720 47 247 1.8E-64 T 28-03-2018 SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 Gene3D G3DSA:3.40.50.720 1 46 1.4E-9 T 28-03-2018 SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 190 9.4E-5 T 28-03-2018 SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 SUPERFAMILY SSF51735 6 246 6.59E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04800 1d67924a10db2d70426dda012a821d15 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 1.2E-63 T 28-03-2018 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Pfam PF00158 Sigma-54 interaction domain 158 320 2.0E-62 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 SUPERFAMILY SSF52540 156 387 2.04E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Gene3D G3DSA:3.40.50.300 153 326 1.0E-22 T 28-03-2018 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 1.3E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 1.3E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Gene3D G3DSA:1.10.8.60 327 390 2.7E-17 T 28-03-2018 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 SMART SM00382 174 317 1.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 SMART SM00448 2 118 1.5E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 SUPERFAMILY SSF52172 1 196 8.54E-30 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 240 255 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Gene3D G3DSA:1.10.10.60 407 445 7.1E-11 T 28-03-2018 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 SUPERFAMILY SSF46689 359 445 5.82E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Pfam PF02954 Bacterial regulatory protein, Fis family 408 443 6.5E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Pfam PF00072 Response regulator receiver domain 4 118 3.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18660 3679a1aaf4e8cdb98e4be135c85963be 448 Gene3D G3DSA:3.40.50.2300 1 144 3.7E-25 T 28-03-2018 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 SUPERFAMILY SSF46689 5 76 2.79E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 1.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 Gene3D G3DSA:1.10.260.40 47 67 0.0015 T 28-03-2018 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 Gene3D G3DSA:1.10.10.60 5 46 1.3E-18 T 28-03-2018 SmaCSM2_RS13490 e2a702c5141567b2672dc3fa6c81abec 214 Gene3D G3DSA:1.10.357.10 68 196 2.2E-15 T 28-03-2018 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 Gene3D G3DSA:3.30.1130.10 15 128 3.1E-39 T 28-03-2018 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 Pfam PF14489 QueF-like protein 184 257 6.5E-27 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 PIRSF PIRSF004750 1 272 6.1E-111 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 SUPERFAMILY SSF55620 174 254 1.33E-8 T 28-03-2018 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 TIGRFAM TIGR03138 QueF: queuine synthase 4 272 7.5E-112 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 Gene3D G3DSA:3.30.1130.10 134 272 2.4E-39 T 28-03-2018 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 15 124 2.5E-46 T 28-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 SmaCSM2_RS19520 9281546cff83895fc39f5258d4f1c615 272 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 272 136.338 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 SmaCSM2_RS20485 e754728d51217decdd6db0056373d559 615 SUPERFAMILY SSF55486 154 589 6.7E-36 T 28-03-2018 SmaCSM2_RS20485 e754728d51217decdd6db0056373d559 615 Pfam PF01432 Peptidase family M3 391 580 3.2E-7 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SmaCSM2_RS20485 e754728d51217decdd6db0056373d559 615 Gene3D G3DSA:1.10.1370.10 136 600 4.3E-10 T 28-03-2018 SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 24 146 1.5E-19 T 28-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 26 149 6.0E-46 T 28-03-2018 SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 126 142 - T 28-03-2018 IPR028871 Blue (type 1) copper protein, binding site SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 Gene3D G3DSA:2.60.40.420 22 148 5.5E-13 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 TIGRFAM TIGR02695 azurin: azurin 24 147 3.0E-53 T 28-03-2018 IPR014068 Azurin SmaCSM2_RS17535 282a217ef44e321110fddcf0131870c9 149 SUPERFAMILY SSF49503 23 147 2.14E-41 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 Gene3D G3DSA:2.40.50.100 95 165 3.4E-8 T 28-03-2018 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 Pfam PF13533 Biotin-lipoyl like 100 133 6.7E-8 T 28-03-2018 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 370 394 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 452 472 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 107 127 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 437 452 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 394 417 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 65 88 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 337 358 7.1E-64 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 Pfam PF13437 HlyD family secretion protein 324 427 5.5E-19 T 28-03-2018 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 Gene3D G3DSA:1.20.1600.10 166 457 6.8E-22 T 28-03-2018 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 55 473 1.9E-122 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 SmaCSM2_RS11450 b820ff86e99aa30f974549bc740fb216 473 ProSitePatterns PS00543 HlyD family secretion proteins signature. 437 459 - T 28-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 PIRSF PIRSF000148 7 342 1.1E-133 T 28-03-2018 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 SUPERFAMILY SSF51735 9 161 2.86E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 SUPERFAMILY SSF55347 133 325 9.52E-75 T 28-03-2018 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 7 338 37.665 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 Gene3D G3DSA:3.30.360.10 145 321 1.4E-73 T 28-03-2018 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 SMART SM00859 9 124 6.7E-45 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 Gene3D G3DSA:3.40.50.720 4 144 9.9E-37 T 28-03-2018 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 123 1.6E-32 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 9 338 1.3E-138 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS15300 acae819e6c11d658dddf74243e12fde6 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 143 324 1.2E-57 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 302 6.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 SUPERFAMILY SSF55874 299 460 2.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 Pfam PF08521 Two-component sensor kinase N-terminal 26 168 1.0E-39 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 SMART SM00387 354 462 7.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 SMART SM00388 244 309 2.9E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 SUPERFAMILY SSF47384 227 302 6.47E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 Gene3D G3DSA:1.10.287.130 234 304 7.7E-13 T 28-03-2018 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 Gene3D G3DSA:3.30.565.10 315 463 4.8E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 460 4.8E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 1.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 1.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 1.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17895 8faf70cde6e6d5bcca39a322623b8152 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Gene3D G3DSA:2.60.40.420 186 387 5.3E-40 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 SUPERFAMILY SSF49503 183 391 1.16E-56 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Pfam PF00394 Multicopper oxidase 189 367 2.0E-33 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 ProSitePatterns PS00079 Multicopper oxidases signature 1. 598 618 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 SUPERFAMILY SSF49503 51 206 1.77E-38 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Gene3D G3DSA:2.60.40.420 43 185 2.5E-29 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 SUPERFAMILY SSF49503 469 620 9.32E-37 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Gene3D G3DSA:2.60.40.420 388 621 4.3E-49 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 ProSitePatterns PS00079 Multicopper oxidases signature 1. 154 174 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 43 5.2E-6 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 ProSitePatterns PS00080 Multicopper oxidases signature 2. 603 614 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Pfam PF07731 Multicopper oxidase 507 621 9.2E-28 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 17 620 0.0 T 28-03-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 SmaCSM2_RS10885 1260fc1dba3ff7f9128bc7e73b8d8073 622 Pfam PF07732 Multicopper oxidase 62 178 6.2E-35 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SmaCSM2_RS01085 61c411066601ec672fe072698f6794b0 803 Pfam PF13954 PapC N-terminal domain 32 159 1.1E-16 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 SmaCSM2_RS01085 61c411066601ec672fe072698f6794b0 803 Pfam PF00577 Outer membrane usher protein 176 712 5.5E-66 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS01085 61c411066601ec672fe072698f6794b0 803 SUPERFAMILY SSF141729 30 138 4.05E-16 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Pfam PF00501 AMP-binding enzyme 31 463 8.6E-108 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Gene3D G3DSA:2.30.38.10 375 456 1.2E-28 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 SUPERFAMILY SSF56801 24 555 1.16E-146 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Gene3D G3DSA:3.30.300.30 457 558 2.2E-24 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Gene3D G3DSA:3.40.50.980 23 217 3.3E-40 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Gene3D G3DSA:3.40.50.980 218 374 1.6E-38 T 28-03-2018 SmaCSM2_RS09920 553843d3ebf58f5bf97c3f0fbf0d72a4 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 546 7.0E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 4120 4285 3.8E-33 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 3583 3743 1.2E-15 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 3502 3570 3.6E-4 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 3982 4057 0.011 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 3308 3497 1.6E-6 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13332 Haemagluttinin repeat 3803 3963 6.0E-20 T 28-03-2018 IPR025157 Hemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 2550 2915 2.1E-5 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 994 1148 3.7E-5 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 2368 2523 5.0E-4 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 753 900 3.8E-6 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 98 378 2.2E-62 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 2203 2367 0.0034 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1256 1378 9.2E-5 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1816 1971 0.0033 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1379 1524 0.009 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 379 433 1.5E-4 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1972 2117 3.0E-5 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 2118 2202 2.0E-4 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1525 1631 0.021 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1149 1255 1.6E-4 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:2.160.20.10 1632 1776 0.013 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05860 haemagglutination activity domain 98 230 2.0E-32 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF13018 Extended Signal Peptide of Type V secretion system 22 42 7.2E-8 T 28-03-2018 IPR024973 ESPR domain SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF04829 Pre-toxin domain with VENN motif 4663 4711 3.0E-12 T 28-03-2018 IPR006914 VENN motif-containing domain SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 130 226 1.5E-21 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 SMART SM00912 111 231 1.4E-46 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Gene3D G3DSA:3.90.70.10 5046 5177 4.4E-21 T 28-03-2018 SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1489 1526 0.72 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1208 1275 3.2E-6 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1714 1774 0.63 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1636 1683 0.0013 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1103 1154 1.1 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 263 355 7.6E-4 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 706 774 3.3 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 2261 2351 4.6E-4 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 504 558 27.0 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 363 425 160.0 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1579 1631 0.017 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 2070 2139 0.096 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1966 2042 0.0098 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 812 865 0.07 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 2195 2247 5.5 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1785 1832 8.7 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1040 1102 12.0 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF05594 Haemagluttinin repeat 1422 1479 0.22 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1790 1817 0.0068 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1120 1154 0.08 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1485 1516 2.1 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 607 633 1.8 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2005 2042 2.6 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2536 2563 0.68 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 851 885 0.0043 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1686 1720 2.7E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 702 738 0.52 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2319 2358 1.1E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 762 797 0.019 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2447 2487 0.001 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2073 2105 0.0011 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1728 1766 6.9E-7 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1044 1073 0.086 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1773 1809 0.0039 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 355 395 4.6E-5 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1751 1777 0.019 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2043 2070 3.8E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1601 1643 0.0013 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2408 2440 2.0 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 867 901 0.0094 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2219 2248 0.0029 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2112 2149 0.0043 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1593 1620 2.0E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 909 944 0.014 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1644 1683 3.5E-6 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1333 1367 8.6E-6 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2374 2407 8.9E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1080 1117 0.95 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 3269 3306 1.5 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2278 2318 0.03 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1002 1033 0.08 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2260 2297 0.033 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1266 1302 0.0053 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 535 571 0.67 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 809 841 0.0028 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1981 2019 0.031 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2150 2189 7.4E-7 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2257 2277 0.95 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1207 1241 5.4E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 824 865 0.0031 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1252 1281 0.17 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1462 1480 1.5 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1524 1554 0.057 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1939 1978 0.15 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1369 1409 1.2 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1286 1324 0.0089 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 954 990 0.0016 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1308 1335 0.013 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1420 1450 0.057 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2575 2594 0.6 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 501 531 0.0016 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1162 1193 0.034 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2467 2504 0.0017 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 375 414 0.013 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 Pfam PF03412 Peptidase C39 family 5042 5176 7.8E-11 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 SUPERFAMILY SSF51126 397 417 9.42E-64 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS00640 8db710ac196044796b7cc14a240fbc54 5177 SUPERFAMILY SSF51126 101 356 9.42E-64 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS17830 b1f4324badf3e6aa58792956568fedbc 305 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 9 295 2.9E-70 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SmaCSM2_RS17830 b1f4324badf3e6aa58792956568fedbc 305 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 8 304 1.0E-115 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 SmaCSM2_RS17830 b1f4324badf3e6aa58792956568fedbc 305 PIRSF PIRSF026649 4 304 5.6E-93 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SmaCSM2_RS17830 b1f4324badf3e6aa58792956568fedbc 305 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 5 304 41.422 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 PIRSF PIRSF006468 7 364 9.9E-134 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 SUPERFAMILY SSF56752 8 360 5.23E-114 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 Pfam PF01063 Amino-transferase class IV 76 319 5.7E-36 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 269 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 Gene3D G3DSA:3.30.470.10 3 180 5.1E-66 T 28-03-2018 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 50 363 2.1E-143 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SmaCSM2_RS03755 0e362e2b55e1aa8caf78a77199913226 364 Gene3D G3DSA:3.20.10.10 181 359 4.4E-55 T 28-03-2018 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 SMART SM01217 846 914 2.7E-17 T 28-03-2018 IPR026891 Fibronectin type III-like domain SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 564 813 2.0E-53 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Pfam PF14310 Fibronectin type III-like domain 846 911 3.1E-15 T 28-03-2018 IPR026891 Fibronectin type III-like domain SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Gene3D G3DSA:3.20.20.300 211 537 6.3E-85 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 281 529 1.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 458 475 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 SUPERFAMILY SSF52279 564 763 3.4E-48 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 SUPERFAMILY SSF52279 794 816 3.4E-48 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Gene3D G3DSA:2.60.40.10 814 928 1.7E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 PRINTS PR00133 Glycosyl hydrolase family 3 signature 357 373 1.7E-25 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 PRINTS PR00133 Glycosyl hydrolase family 3 signature 388 404 1.7E-25 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 PRINTS PR00133 Glycosyl hydrolase family 3 signature 458 476 1.7E-25 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 PRINTS PR00133 Glycosyl hydrolase family 3 signature 311 330 1.7E-25 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 PRINTS PR00133 Glycosyl hydrolase family 3 signature 281 297 1.7E-25 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 SUPERFAMILY SSF51445 224 546 1.47E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS12955 f236a48c1277da4cdec8896e247d122b 931 Gene3D G3DSA:3.40.50.1700 548 813 2.3E-67 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.026 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 1.1E-35 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 Pfam PF01084 Ribosomal protein S18 19 68 1.6E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 Gene3D G3DSA:4.10.640.10 1 76 4.7E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 SUPERFAMILY SSF46911 3 74 1.26E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.5E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.5E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.5E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.5E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13895 d579821443c977e1b5f5aa0b37ff2a0f 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 4.0E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 31 55 2.0E-5 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 Pfam PF02609 Exonuclease VII small subunit 15 64 2.7E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 SUPERFAMILY SSF116842 14 72 1.57E-17 T 28-03-2018 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 14 74 15.297 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 PIRSF PIRSF006488 1 85 1.7E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 Gene3D G3DSA:1.10.287.1040 13 79 1.9E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS15535 952450fc3da1c264dc6132fcec7d525b 86 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 15 67 1.0E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS10315 a558d5174700def2e2c9ccc86c865494 101 SUPERFAMILY SSF101498 21 94 1.83E-12 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 SmaCSM2_RS10315 a558d5174700def2e2c9ccc86c865494 101 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 94 5.0E-15 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal SmaCSM2_RS10315 a558d5174700def2e2c9ccc86c865494 101 Gene3D G3DSA:1.10.287.1160 66 94 3.7E-10 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 SmaCSM2_RS10315 a558d5174700def2e2c9ccc86c865494 101 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 4 95 1.3E-17 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 SUPERFAMILY SSF46894 137 206 1.22E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 Gene3D G3DSA:1.10.10.10 125 208 1.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 SMART SM00448 1 114 3.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 200 6.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 Pfam PF00072 Response regulator receiver domain 3 114 3.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 SMART SM00421 145 202 1.6E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 Gene3D G3DSA:3.40.50.2300 1 124 2.3E-34 T 28-03-2018 SmaCSM2_RS10210 05f49decc5914d421a9796c310e5e4b0 210 SUPERFAMILY SSF52172 2 129 4.27E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 SMART SM00363 3 65 2.0E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 SUPERFAMILY SSF55174 5 91 3.01E-13 T 28-03-2018 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 227 7.6E-45 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 Pfam PF01479 S4 domain 5 44 8.4E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 Gene3D G3DSA:3.30.70.580 63 145 9.9E-16 T 28-03-2018 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 SUPERFAMILY SSF55120 64 228 1.31E-38 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 Gene3D G3DSA:3.10.290.10 5 62 1.2E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 Gene3D G3DSA:3.30.70.1560 146 214 4.4E-20 T 28-03-2018 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS04225 021a48cee402c263f2c3f629af4a2ff0 240 Pfam PF00849 RNA pseudouridylate synthase 64 197 4.2E-18 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS13265 4dbe95928c2b70aa074fefe41f54e6ed 216 Pfam PF08241 Methyltransferase domain 52 149 7.4E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS13265 4dbe95928c2b70aa074fefe41f54e6ed 216 SUPERFAMILY SSF53335 31 192 3.73E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS13265 4dbe95928c2b70aa074fefe41f54e6ed 216 Gene3D G3DSA:3.40.50.150 10 215 1.8E-29 T 28-03-2018 SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 SUPERFAMILY SSF52788 1 109 1.44E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 Gene3D G3DSA:3.40.50.2300 1 37 2.6E-8 T 28-03-2018 SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 SMART SM00226 2 96 0.0036 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 PIRSF PIRSF029416 1 109 1.4E-41 T 28-03-2018 IPR016919 Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 Gene3D G3DSA:3.40.50.2300 38 111 4.9E-5 T 28-03-2018 SmaCSM2_RS14985 c2d46d9feffb230bec31420e1c0a1523 113 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 83 1.1E-5 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS02160 b8ec6203b86c28ef64f62eecce30b7d9 280 Gene3D G3DSA:3.40.50.150 106 165 0.044 T 28-03-2018 SmaCSM2_RS02160 b8ec6203b86c28ef64f62eecce30b7d9 280 Gene3D G3DSA:3.40.50.150 172 273 1.8E-16 T 28-03-2018 SmaCSM2_RS02160 b8ec6203b86c28ef64f62eecce30b7d9 280 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 180 243 2.0E-5 T 28-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 SmaCSM2_RS02160 b8ec6203b86c28ef64f62eecce30b7d9 280 SUPERFAMILY SSF53335 65 268 4.22E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 15 435 48.381 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 138 435 8.2E-120 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 SUPERFAMILY SSF56762 34 435 1.57E-132 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 24 435 1.6E-179 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 Gene3D G3DSA:1.10.645.10 248 427 1.4E-43 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15160 fd8bfe3c87b5e5347485a705a111ef8d 435 Gene3D G3DSA:1.10.645.10 20 247 3.5E-60 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 452 6.8E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 4.5E-7 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Gene3D G3DSA:1.20.140.10 277 468 2.7E-40 T 28-03-2018 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Gene3D G3DSA:1.10.540.10 25 161 2.1E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 164 272 7.6E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 SUPERFAMILY SSF56645 38 280 2.75E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 590 5.2E-30 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Gene3D G3DSA:2.40.110.10 162 275 2.5E-22 T 28-03-2018 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 SUPERFAMILY SSF47203 288 460 2.74E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS14860 7c608805cd3b863f98c3e92d0f505459 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 158 7.7E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS01655 5960a2928c3a2502f0cdc81fc47e36c4 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 4 28 4.9E-8 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 PIRSF PIRSF001109 1 481 8.5E-190 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 480 2.9E-147 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SUPERFAMILY SSF51735 239 401 6.93E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SMART SM00997 239 401 4.3E-108 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SMART SM00996 13 480 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SUPERFAMILY SSF52283 12 154 1.47E-113 T 28-03-2018 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SUPERFAMILY SSF52283 402 481 1.47E-113 T 28-03-2018 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 SUPERFAMILY SSF52283 191 238 1.47E-113 T 28-03-2018 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 261 278 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 239 401 1.9E-81 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 473 1.8E-186 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 85 99 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 Gene3D G3DSA:3.40.50.1480 2 257 1.2E-105 T 28-03-2018 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 473 48.225 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 SmaCSM2_RS03365 ed7a6314b479ef050edba8e452e3259d 481 Gene3D G3DSA:3.40.50.1480 258 454 6.1E-85 T 28-03-2018 SmaCSM2_RS13700 7e65c152d20e4e663c262107f90ecdc8 284 Gene3D G3DSA:3.40.630.40 1 282 6.8E-72 T 28-03-2018 SmaCSM2_RS13700 7e65c152d20e4e663c262107f90ecdc8 284 Pfam PF05013 N-formylglutamate amidohydrolase 15 238 2.9E-63 T 28-03-2018 IPR007709 N-formylglutamate amidohydrolase SmaCSM2_RS13700 7e65c152d20e4e663c262107f90ecdc8 284 SUPERFAMILY SSF53187 4 279 3.35E-76 T 28-03-2018 SmaCSM2_RS13700 7e65c152d20e4e663c262107f90ecdc8 284 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 6 279 1.3E-115 T 28-03-2018 IPR010247 N-formylglutamate deformylase SmaCSM2_RS14500 0fd675491151962b3f1dfe552ea99341 205 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 25 189 8.1E-52 T 28-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 SmaCSM2_RS14500 0fd675491151962b3f1dfe552ea99341 205 Gene3D G3DSA:3.40.30.10 44 193 5.6E-26 T 28-03-2018 SmaCSM2_RS14500 0fd675491151962b3f1dfe552ea99341 205 SUPERFAMILY SSF52833 57 189 8.62E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14500 0fd675491151962b3f1dfe552ea99341 205 Pfam PF08534 Redoxin 54 181 6.0E-16 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SmaCSM2_RS14500 0fd675491151962b3f1dfe552ea99341 205 ProSitePatterns PS00194 Thioredoxin family active site. 82 100 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS10970 978a50b540b4b27c4d9bf0142014ce96 81 Gene3D G3DSA:1.10.260.40 1 80 8.0E-17 T 28-03-2018 SmaCSM2_RS10970 978a50b540b4b27c4d9bf0142014ce96 81 SMART SM00530 16 71 3.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS10970 978a50b540b4b27c4d9bf0142014ce96 81 Pfam PF13560 Helix-turn-helix domain 16 67 6.9E-11 T 28-03-2018 SmaCSM2_RS10970 978a50b540b4b27c4d9bf0142014ce96 81 SUPERFAMILY SSF47413 10 73 3.94E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 3.1E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 3.9E-220 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 Gene3D G3DSA:3.90.180.10 1 189 6.8E-59 T 28-03-2018 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 1.1E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 SMART SM00829 10 367 4.4E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 Gene3D G3DSA:3.40.50.720 190 312 1.7E-24 T 28-03-2018 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 SUPERFAMILY SSF50129 318 369 9.89E-12 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 Gene3D G3DSA:3.90.180.10 314 369 1.4E-5 T 28-03-2018 SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 SUPERFAMILY SSF51735 161 333 3.74E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20230 d84cf8d671414dc8a77c86b2e506bab9 369 SUPERFAMILY SSF50129 1 185 3.96E-71 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 SUPERFAMILY SSF51735 2 183 3.56E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 182 9.5E-19 T 28-03-2018 SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 163 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 156 0.0022 T 28-03-2018 SmaCSM2_RS04955 db87132c08307cb7a162b4100a278bbd 200 Gene3D G3DSA:3.40.50.720 1 199 6.2E-33 T 28-03-2018 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 SUPERFAMILY SSF46689 215 262 6.53E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 Pfam PF12833 Helix-turn-helix domain 235 315 1.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 SMART SM00342 229 315 7.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 Gene3D G3DSA:1.10.10.60 266 323 6.3E-6 T 28-03-2018 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 Gene3D G3DSA:1.10.10.60 205 265 9.7E-8 T 28-03-2018 SmaCSM2_RS12705 d8b9e03ada1cc57164c1a7507d33197c 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 311 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS19075 6d49562e870fc9cce855f4da0b2136b5 254 Gene3D G3DSA:3.30.700.10 144 254 5.1E-20 T 28-03-2018 SmaCSM2_RS19075 6d49562e870fc9cce855f4da0b2136b5 254 SUPERFAMILY SSF54523 141 253 3.45E-20 T 28-03-2018 SmaCSM2_RS19075 6d49562e870fc9cce855f4da0b2136b5 254 Gene3D G3DSA:3.30.1490.40 3 57 1.6E-4 T 28-03-2018 IPR035445 GYF-like domain SmaCSM2_RS19075 6d49562e870fc9cce855f4da0b2136b5 254 Pfam PF14237 Domain of unknown function (DUF4339) 4 47 2.7E-15 T 28-03-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 SmaCSM2_RS19075 6d49562e870fc9cce855f4da0b2136b5 254 Pfam PF00114 Pilin (bacterial filament) 148 253 1.9E-13 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Pfam PF01612 3'-5' exonuclease 326 512 5.2E-38 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 165 2.4E-48 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Pfam PF00476 DNA polymerase family A 546 922 5.1E-151 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SUPERFAMILY SSF88723 1 165 1.57E-51 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:3.40.50.1010 2 179 5.0E-63 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SUPERFAMILY SSF53098 323 512 2.9E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SUPERFAMILY SSF56672 520 924 1.56E-155 T 28-03-2018 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SMART SM00474 326 513 4.2E-35 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:3.30.70.370 809 924 4.6E-25 T 28-03-2018 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SUPERFAMILY SSF47807 167 280 4.19E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SMART SM00475 2 256 3.1E-110 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 TIGRFAM TIGR00593 pola: DNA polymerase I 4 924 7.3E-279 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 166 258 1.1E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:3.30.420.10 320 538 9.0E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 ProSitePatterns PS00447 DNA polymerase family A signature. 750 769 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SMART SM00482 682 888 3.2E-111 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:1.10.150.20 704 808 3.4E-41 T 28-03-2018 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 SMART SM00279 168 203 6.2E-14 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 787 798 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 841 857 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 726 739 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 809 820 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 696 719 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 673 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 871 884 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 674 689 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 775 7.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:1.20.1060.10 539 654 5.9E-34 T 28-03-2018 SmaCSM2_RS21215 49ff0d2d60c2ee695710118b52becced 924 Gene3D G3DSA:1.10.150.20 180 257 1.3E-24 T 28-03-2018 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Pfam PF03412 Peptidase C39 family 17 140 3.6E-12 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 SMART SM00382 505 691 2.2E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 SUPERFAMILY SSF52540 469 716 1.23E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Gene3D G3DSA:3.90.70.10 13 144 9.1E-17 T 28-03-2018 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Pfam PF00005 ABC transporter 497 645 2.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Gene3D G3DSA:1.20.1560.10 150 468 2.6E-45 T 28-03-2018 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 SUPERFAMILY SSF90123 153 460 3.01E-66 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Gene3D G3DSA:3.40.50.300 469 719 2.0E-77 T 28-03-2018 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 Pfam PF00664 ABC transporter transmembrane region 166 432 5.9E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 24 717 0.0 T 28-03-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 SmaCSM2_RS11455 ba74f5784be34c194f24bd39b16732f2 720 ProSitePatterns PS00211 ABC transporters family signature. 617 631 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Gene3D G3DSA:1.20.140.10 219 382 2.2E-57 T 28-03-2018 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 SUPERFAMILY SSF56645 2 242 9.56E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 SUPERFAMILY SSF47203 228 381 4.83E-58 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Gene3D G3DSA:1.10.540.10 1 120 1.2E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 5.3E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 PIRSF PIRSF016578 218 375 4.0E-11 T 28-03-2018 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 PIRSF PIRSF016578 128 195 0.014 T 28-03-2018 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 PIRSF PIRSF016578 4 97 3.3E-7 T 28-03-2018 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.2E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.4E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS14015 c452a05581982e9e0f96b34ce563f0a5 382 Gene3D G3DSA:2.40.110.10 121 218 1.4E-33 T 28-03-2018 SmaCSM2_RS20805 b36c5a7d6c15c27e23e970490c09cc0c 287 SUPERFAMILY SSF82171 43 212 1.57E-13 T 28-03-2018 SmaCSM2_RS20805 b36c5a7d6c15c27e23e970490c09cc0c 287 Gene3D G3DSA:2.130.10.150 39 280 1.5E-15 T 28-03-2018 SmaCSM2_RS20805 b36c5a7d6c15c27e23e970490c09cc0c 287 Pfam PF07676 WD40-like Beta Propeller Repeat 34 66 4.9E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS20805 b36c5a7d6c15c27e23e970490c09cc0c 287 Pfam PF07676 WD40-like Beta Propeller Repeat 87 114 0.011 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS20805 b36c5a7d6c15c27e23e970490c09cc0c 287 Pfam PF07676 WD40-like Beta Propeller Repeat 130 167 6.6E-6 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 347 3.4E-29 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 Gene3D G3DSA:3.40.50.300 258 368 5.8E-12 T 28-03-2018 SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 Gene3D G3DSA:3.40.50.300 1 196 9.7E-10 T 28-03-2018 SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 SUPERFAMILY SSF52540 258 350 1.23E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 SUPERFAMILY SSF52540 1 177 1.23E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06465 8035ed53cc51953855c675d03acefb39 386 PIRSF PIRSF029347 1 386 4.3E-149 T 28-03-2018 IPR014555 RecF-like SmaCSM2_RS15550 c46c147ed03a2a016828a8439a130901 455 SUPERFAMILY SSF111283 21 454 1.06E-120 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS15550 c46c147ed03a2a016828a8439a130901 455 Gene3D G3DSA:3.30.2290.10 8 240 3.4E-56 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SmaCSM2_RS15550 c46c147ed03a2a016828a8439a130901 455 Pfam PF01523 Putative modulator of DNA gyrase 39 331 3.5E-60 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS02405 902bc795374f854604158620a58d3896 155 Pfam PF01641 SelR domain 20 134 2.4E-47 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02405 902bc795374f854604158620a58d3896 155 SUPERFAMILY SSF51316 14 138 2.62E-52 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS02405 902bc795374f854604158620a58d3896 155 Gene3D G3DSA:2.170.150.20 10 148 7.8E-51 T 28-03-2018 SmaCSM2_RS02405 902bc795374f854604158620a58d3896 155 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 15 136 1.9E-44 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02405 902bc795374f854604158620a58d3896 155 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 10 136 34.589 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 Gene3D G3DSA:3.40.50.720 144 269 1.8E-29 T 28-03-2018 SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 SUPERFAMILY SSF51735 286 553 2.49E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 Pfam PF13727 CoA-binding domain 69 243 5.8E-18 T 28-03-2018 SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 SUPERFAMILY SSF51735 148 276 3.46E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 Pfam PF02719 Polysaccharide biosynthesis protein 288 570 7.1E-111 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain SmaCSM2_RS09015 efc3c8d4d717a01a9174a9f0fdc2caf3 637 Gene3D G3DSA:3.40.50.720 282 608 2.7E-65 T 28-03-2018 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Gene3D G3DSA:1.10.1040.10 354 437 1.7E-9 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Gene3D G3DSA:3.40.50.720 2 192 1.7E-40 T 28-03-2018 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 SUPERFAMILY SSF48179 193 312 7.14E-19 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Gene3D G3DSA:1.10.1040.10 193 300 1.5E-12 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 SUPERFAMILY SSF48179 345 458 1.02E-16 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 195 294 7.7E-9 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Pfam PF00378 Enoyl-CoA hydratase/isomerase 485 622 4.0E-16 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 SUPERFAMILY SSF52096 474 787 1.36E-39 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Gene3D G3DSA:3.90.226.10 474 788 9.8E-38 T 28-03-2018 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 192 3.6E-41 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SmaCSM2_RS09030 f1bfa27ce9cec0ba0e34a04e1f7343f0 790 SUPERFAMILY SSF51735 7 193 3.69E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16275 3e0d5f2c731ddc9f0397ca0dd7ae5bc6 214 Pfam PF04264 YceI-like domain 24 187 1.1E-32 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16275 3e0d5f2c731ddc9f0397ca0dd7ae5bc6 214 Gene3D G3DSA:2.40.128.110 22 191 1.1E-39 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16275 3e0d5f2c731ddc9f0397ca0dd7ae5bc6 214 SMART SM00867 23 188 1.5E-44 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16275 3e0d5f2c731ddc9f0397ca0dd7ae5bc6 214 SUPERFAMILY SSF101874 20 188 1.44E-41 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS00070 f2ee163372c371e1531675b067e6b52f 247 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 247 89.869 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 SmaCSM2_RS00070 f2ee163372c371e1531675b067e6b52f 247 Gene3D G3DSA:3.20.20.70 2 247 3.9E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00070 f2ee163372c371e1531675b067e6b52f 247 SUPERFAMILY SSF63892 1 247 1.57E-79 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 SmaCSM2_RS00070 f2ee163372c371e1531675b067e6b52f 247 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 246 2.1E-85 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 SmaCSM2_RS00070 f2ee163372c371e1531675b067e6b52f 247 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 246 1.1E-67 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 Pfam PF13091 PLD-like domain 91 245 3.3E-18 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 Pfam PF13091 PLD-like domain 532 581 5.2E-9 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 Gene3D G3DSA:3.30.870.10 7 261 1.4E-30 T 28-03-2018 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 SMART SM00155 530 557 0.026 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 SMART SM00155 186 213 0.0015 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 SUPERFAMILY SSF56024 40 255 3.14E-37 T 28-03-2018 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 SUPERFAMILY SSF56024 331 423 5.76E-24 T 28-03-2018 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 SUPERFAMILY SSF56024 527 603 5.76E-24 T 28-03-2018 SmaCSM2_RS00575 390077dd5fae1ff4a4e553fc8b6786ad 685 Gene3D G3DSA:3.30.870.10 330 600 4.5E-19 T 28-03-2018 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Gene3D G3DSA:3.30.310.50 370 448 2.5E-16 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 SUPERFAMILY SSF53738 150 253 1.18E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Gene3D G3DSA:3.40.120.10 260 369 4.1E-24 T 28-03-2018 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 128 2.1E-34 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 250 1.2E-21 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Gene3D G3DSA:3.40.120.10 158 259 2.1E-28 T 28-03-2018 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 255 365 3.3E-23 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 SUPERFAMILY SSF53738 255 360 3.88E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 230 245 2.8E-28 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 167 186 2.8E-28 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 2.8E-28 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 201 214 2.8E-28 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 SUPERFAMILY SSF55957 365 448 1.74E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Gene3D G3DSA:3.40.120.10 4 157 2.9E-37 T 28-03-2018 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 444 8.8E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 91 100 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS02800 d07e033156d30c6cfbea8a607afea3a8 448 SUPERFAMILY SSF53738 5 174 9.12E-36 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 SUPERFAMILY SSF46955 6 127 2.2E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 Gene3D G3DSA:1.10.1660.10 61 131 1.8E-11 T 28-03-2018 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 5 140 6.0E-67 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 9.4E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 9.4E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 9.4E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 SMART SM00422 6 74 2.6E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 Pfam PF00376 MerR family regulatory protein 7 43 7.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 Pfam PF09278 MerR, DNA binding 48 113 4.1E-17 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 Gene3D G3DSA:1.10.1660.10 1 60 6.7E-19 T 28-03-2018 SmaCSM2_RS04950 a346edd222f4e964cb64bfc14f10e882 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 1.1E-66 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 300 17.38 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 SUPERFAMILY SSF88697 244 301 2.98E-6 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 239 4.0E-18 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 SUPERFAMILY SSF55120 8 222 1.47E-69 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 179 4.8E-49 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Gene3D G3DSA:3.30.2350.10 8 226 1.1E-71 T 28-03-2018 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 245 298 8.0E-9 T 28-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15075 da8de1b07a21b24fb0bc6490615f7add 302 Gene3D G3DSA:2.30.130.10 243 302 5.6E-12 T 28-03-2018 IPR002478 PUA domain GO:0003723 SmaCSM2_RS09650 278467dfa7e4303a82f84cbf9fa88bd7 331 Pfam PF00294 pfkB family carbohydrate kinase 3 315 3.9E-63 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SmaCSM2_RS09650 278467dfa7e4303a82f84cbf9fa88bd7 331 SUPERFAMILY SSF53613 2 324 2.96E-78 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS09650 278467dfa7e4303a82f84cbf9fa88bd7 331 Gene3D G3DSA:3.40.1190.20 3 329 2.9E-74 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS09650 278467dfa7e4303a82f84cbf9fa88bd7 331 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SmaCSM2_RS10025 2f936c45963edfbd30cf34eef28170ea 163 Gene3D G3DSA:2.30.30.40 97 141 1.1E-19 T 28-03-2018 SmaCSM2_RS10025 2f936c45963edfbd30cf34eef28170ea 163 SUPERFAMILY SSF50341 14 151 2.09E-42 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10025 2f936c45963edfbd30cf34eef28170ea 163 Gene3D G3DSA:2.40.50.180 31 96 1.3E-21 T 28-03-2018 SmaCSM2_RS10025 2f936c45963edfbd30cf34eef28170ea 163 Pfam PF01584 CheW-like domain 14 150 1.4E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10025 2f936c45963edfbd30cf34eef28170ea 163 SMART SM00260 10 147 2.1E-41 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 SUPERFAMILY SSF53732 3 647 3.27E-223 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Gene3D G3DSA:3.30.499.10 29 237 7.2E-72 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Gene3D G3DSA:3.30.499.10 371 597 1.8E-64 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Pfam PF00694 Aconitase C-terminal domain 713 844 7.8E-45 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 ProSitePatterns PS01244 Aconitase family signature 2. 514 527 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 SUPERFAMILY SSF52016 652 914 1.75E-84 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 ProSitePatterns PS00450 Aconitase family signature 1. 448 464 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Pfam PF00330 Aconitase family (aconitate hydratase) 67 583 2.8E-179 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Gene3D G3DSA:3.40.1060.10 238 370 4.4E-45 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 168 176 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 371 385 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 277 290 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 452 463 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 514 527 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 144 157 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 291 304 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 201 214 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 PRINTS PR00415 Aconitase family signature 215 230 5.3E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 16 914 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 SmaCSM2_RS09950 0e13bf53f975866a8339c77bebf877fe 917 Gene3D G3DSA:3.20.19.10 674 916 6.5E-92 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 Gene3D G3DSA:3.30.565.10 314 467 5.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 Pfam PF00672 HAMP domain 192 240 3.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SMART SM00388 245 309 1.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 465 2.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SMART SM00304 192 244 1.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 309 4.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SUPERFAMILY SSF158472 193 241 4.71E-8 T 28-03-2018 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SMART SM00387 355 467 3.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 Gene3D G3DSA:1.10.287.130 235 304 1.2E-13 T 28-03-2018 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SUPERFAMILY SSF55874 298 464 3.14E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 3.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 3.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 3.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 3.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS20710 bd1bc341d33215abf70a35517a0799eb 467 SUPERFAMILY SSF47384 228 310 5.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 SUPERFAMILY SSF55120 2 177 1.36E-41 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 Gene3D G3DSA:3.30.70.580 1 82 3.8E-15 T 28-03-2018 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 Pfam PF00849 RNA pseudouridylate synthase 2 149 1.2E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 6 178 1.3E-52 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 Gene3D G3DSA:3.30.70.1560 83 165 3.5E-27 T 28-03-2018 SmaCSM2_RS20960 e9096716b36e94c0adb618c5ee562b22 179 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 39 53 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 SUPERFAMILY SSF46689 287 335 4.12E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 SUPERFAMILY SSF52317 18 216 9.49E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 Gene3D G3DSA:1.10.10.60 243 285 1.7E-7 T 28-03-2018 SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 Gene3D G3DSA:3.40.50.880 18 242 4.4E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 Gene3D G3DSA:1.10.10.60 286 336 2.9E-6 T 28-03-2018 SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 Pfam PF12833 Helix-turn-helix domain 258 335 6.9E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 Pfam PF01965 DJ-1/PfpI family 43 199 3.1E-7 T 28-03-2018 IPR002818 DJ-1/PfpI SmaCSM2_RS20270 bc3fe0bd26e830731c16d9bc059aa831 337 SMART SM00342 251 334 2.2E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 276 1.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 SMART SM00387 322 423 1.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 Gene3D G3DSA:1.10.287.130 189 274 1.7E-11 T 28-03-2018 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 SUPERFAMILY SSF47384 196 275 2.94E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 SUPERFAMILY SSF55874 277 422 2.49E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 SMART SM00388 213 279 1.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 Gene3D G3DSA:3.30.565.10 275 423 2.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03485 0448e9a5c1401e41ec984131444f3c4c 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 421 8.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 SUPERFAMILY SSF55874 285 440 5.89E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 Gene3D G3DSA:1.10.287.130 227 291 1.3E-6 T 28-03-2018 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 7.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 SUPERFAMILY SSF47384 220 294 1.18E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 SMART SM00388 237 295 6.0E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 440 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 SMART SM00387 339 444 1.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS07295 ef8d8cdf6e8af2e31a3b08571b91dce1 447 Gene3D G3DSA:3.30.565.10 299 446 3.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82693 277 333 4.19E-19 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82693 156 191 4.19E-19 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82693 567 668 7.32E-8 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82866 299 507 3.66E-33 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Pfam PF00873 AcrB/AcrD/AcrF family 6 1048 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:3.30.2090.10 724 828 1.9E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.0E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:3.30.2090.10 190 277 4.3E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1052 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:1.20.1640.10 829 1050 1.3E-37 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82714 725 827 5.1E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82693 42 127 1.22E-23 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82866 826 1051 9.94E-55 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:1.20.1640.10 294 519 2.3E-34 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:3.30.70.1430 42 143 5.8E-24 T 28-03-2018 SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 SUPERFAMILY SSF82714 192 274 2.22E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10925 044eefdc42d35e83ed36c073ae1fc957 1063 Gene3D G3DSA:3.30.70.1430 568 669 1.1E-16 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 SUPERFAMILY SSF51905 280 369 2.88E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 SUPERFAMILY SSF51905 3 195 2.88E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 5.2E-43 T 28-03-2018 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 Pfam PF01494 FAD binding domain 3 359 3.7E-63 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS13485 ed31c53b06285f0a156822e5d644e8ae 509 Gene3D G3DSA:3.50.50.60 2 403 9.9E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS00185 482f9a5aa370a0dd1010c93b7191b21b 236 Gene3D G3DSA:2.60.120.620 7 232 1.3E-19 T 28-03-2018 SmaCSM2_RS00185 482f9a5aa370a0dd1010c93b7191b21b 236 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 136 224 1.2E-7 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 81 89 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 Pfam PF01799 [2Fe-2S] binding domain 115 202 1.6E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 48 97 5.9E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 SUPERFAMILY SSF54292 45 129 3.8E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 SUPERFAMILY SSF47741 126 209 4.19E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 Gene3D G3DSA:3.10.20.30 41 116 1.1E-27 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS11185 83be4e49a40b2e150bc29cd313f496b6 215 Gene3D G3DSA:1.10.150.120 117 214 4.6E-35 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Gene3D G3DSA:3.40.190.10 9 118 8.0E-27 T 28-03-2018 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 209 301 6.8E-16 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 162 183 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 SUPERFAMILY SSF53850 12 228 5.04E-62 T 28-03-2018 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 12 303 30.703 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 13 201 1.6E-53 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Pfam PF01634 ATP phosphoribosyltransferase 60 222 2.4E-44 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Gene3D G3DSA:3.40.190.10 119 198 1.5E-30 T 28-03-2018 SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Gene3D G3DSA:3.30.70.120 233 302 1.7E-4 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SmaCSM2_RS09535 bd13f354204dc75a8c80e648978cdde2 303 Pfam PF08029 HisG, C-terminal domain 230 300 1.6E-8 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 Gene3D G3DSA:3.40.50.150 2 190 2.3E-33 T 28-03-2018 SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 125 131 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 SUPERFAMILY SSF53335 10 186 2.35E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 PIRSF PIRSF004553 10 189 7.7E-43 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 Pfam PF03602 Conserved hypothetical protein 95 11 185 7.1E-50 T 28-03-2018 SmaCSM2_RS08505 dd9eb8027d3b411917e7f7e5f1230281 192 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 9 187 4.0E-42 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 SUPERFAMILY SSF53732 22 594 5.23E-184 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Pfam PF00330 Aconitase family (aconitate hydratase) 70 540 2.3E-147 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Gene3D G3DSA:3.30.499.10 359 554 1.2E-54 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 867 0.0 T 28-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Pfam PF00694 Aconitase C-terminal domain 664 795 3.9E-30 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Gene3D G3DSA:3.30.499.10 1 227 6.1E-59 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Gene3D G3DSA:3.40.1060.10 228 358 4.7E-40 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 Gene3D G3DSA:3.20.19.10 627 867 4.0E-67 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 471 484 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 281 294 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 360 374 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 267 280 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 162 170 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 409 420 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 138 151 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 205 220 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 PRINTS PR00415 Aconitase family signature 191 204 3.6E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS16195 62aa59ebfc209e94f9f37d741f1d6b56 872 SUPERFAMILY SSF52016 606 865 3.14E-68 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 Pfam PF00154 recA bacterial DNA recombination protein 7 270 4.3E-139 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 Hamap MF_00268 Protein RecA [recA]. 5 331 50.502 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 326 1.7E-165 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 SUPERFAMILY SSF54752 270 327 3.53E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 165 194 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 212 240 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 127 156 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 245 274 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 93 122 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 PRINTS PR00142 RecA protein signature 299 316 1.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 SMART SM00382 57 230 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 ProSitePatterns PS00321 recA signature. 215 223 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 SUPERFAMILY SSF52540 7 269 3.27E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 Gene3D G3DSA:3.30.250.10 271 328 1.3E-25 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SmaCSM2_RS08145 af8bb850bc659b1f5098a7daca6823c7 345 Gene3D G3DSA:3.40.50.300 26 270 1.2E-43 T 28-03-2018 SmaCSM2_RS19020 38235134a2fd8f2c7896ad350724affb 512 PIRSF PIRSF026631 14 512 1.5E-100 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 SmaCSM2_RS19020 38235134a2fd8f2c7896ad350724affb 512 Pfam PF03703 Bacterial PH domain 76 153 1.9E-19 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SmaCSM2_RS19020 38235134a2fd8f2c7896ad350724affb 512 Pfam PF03703 Bacterial PH domain 422 500 4.4E-11 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SmaCSM2_RS19020 38235134a2fd8f2c7896ad350724affb 512 Pfam PF03703 Bacterial PH domain 273 332 9.9E-11 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SMART SM01086 769 858 1.8E-36 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Gene3D G3DSA:3.40.50.300 552 768 6.9E-53 T 28-03-2018 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 849 1.5E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 763 1.0E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Gene3D G3DSA:3.40.50.300 157 342 3.1E-24 T 28-03-2018 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SMART SM00382 597 770 7.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SMART SM00382 198 343 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SUPERFAMILY SSF81923 4 156 2.65E-39 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SUPERFAMILY SSF52540 159 545 2.29E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 9.5E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 5.6E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.6E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 SUPERFAMILY SSF52540 546 854 2.37E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Gene3D G3DSA:1.10.8.60 343 547 4.2E-47 T 28-03-2018 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Gene3D G3DSA:1.10.8.60 769 861 2.5E-22 T 28-03-2018 SmaCSM2_RS16810 69116a0f12db9867bb135ab3bd31046f 861 Gene3D G3DSA:1.10.1780.10 1 150 5.8E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Gene3D G3DSA:1.20.1110.10 681 917 4.4E-33 T 28-03-2018 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Gene3D G3DSA:2.70.150.10 58 291 8.1E-40 T 28-03-2018 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Gene3D G3DSA:3.40.1110.10 349 562 3.4E-40 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF56784 553 703 1.8E-38 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF81660 361 564 1.44E-40 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Pfam PF00689 Cation transporting ATPase, C-terminus 743 910 1.0E-13 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 48 919 0.0 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Pfam PF00122 E1-E2 ATPase 195 371 4.5E-42 T 28-03-2018 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF81665 53 160 3.27E-105 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF81665 293 386 3.27E-105 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF81665 709 917 3.27E-105 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 198 426 1.1E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 632 749 1.1E-29 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Pfam PF00702 haloacid dehalogenase-like hydrolase 388 674 2.7E-19 T 28-03-2018 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Gene3D G3DSA:3.40.50.1000 563 680 1.3E-15 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SUPERFAMILY SSF81653 188 289 2.09E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 Pfam PF00690 Cation transporter/ATPase, N-terminus 52 117 2.0E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 394 400 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 788 804 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 322 341 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 718 733 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 305 321 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 768 781 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 823 844 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 426 439 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 736 747 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 PRINTS PR01836 Magnesium-transporting ATPase signature 873 894 2.4E-75 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SmaCSM2_RS11750 6ae93a1e5cc6def926f11ecb56f2245c 919 SMART SM00831 49 122 3.8E-11 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Gene3D G3DSA:1.10.8.70 317 361 3.0E-9 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 3.6E-24 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 3.6E-24 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 3.6E-24 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 3.6E-24 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 3.6E-24 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 SUPERFAMILY SSF48163 299 461 2.49E-37 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Gene3D G3DSA:1.10.1160.10 232 315 6.5E-28 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Gene3D G3DSA:3.40.50.620 1 127 4.0E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 461 30.596 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 SUPERFAMILY SSF52374 4 293 1.93E-105 T 28-03-2018 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Gene3D G3DSA:1.10.10.350 367 467 1.3E-21 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 458 6.1E-167 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 305 4.8E-102 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS06360 c1a5425cee86f1689f408cd460f2d95a 467 Gene3D G3DSA:3.40.50.620 128 231 2.3E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 Gene3D G3DSA:3.40.630.10 165 492 3.7E-132 T 28-03-2018 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 SUPERFAMILY SSF52949 3 179 3.18E-41 T 28-03-2018 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 181 481 7.9E-119 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 5 490 35.704 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 145 4.7E-29 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 2.7E-50 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 2.7E-50 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 2.7E-50 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 2.7E-50 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 2.7E-50 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 Gene3D G3DSA:3.40.220.10 1 163 4.1E-34 T 28-03-2018 SmaCSM2_RS02900 a7657e309e09678fd5f328a660775bd0 492 SUPERFAMILY SSF53187 174 487 1.66E-118 T 28-03-2018 SmaCSM2_RS08035 7dbb352da00762a6f4e090ac34d8f98f 117 Gene3D G3DSA:1.20.5.170 30 71 1.6E-4 T 28-03-2018 SmaCSM2_RS08035 7dbb352da00762a6f4e090ac34d8f98f 117 Pfam PF04977 Septum formation initiator 14 92 5.4E-29 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SmaCSM2_RS08035 7dbb352da00762a6f4e090ac34d8f98f 117 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 93 35.82 T 28-03-2018 IPR023081 Cell division protein FtsB SmaCSM2_RS11420 ece7d689da59257c055cab06c61955c8 724 Pfam PF00593 TonB dependent receptor 250 722 4.9E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11420 ece7d689da59257c055cab06c61955c8 724 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 155 3.6E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11420 ece7d689da59257c055cab06c61955c8 724 SUPERFAMILY SSF56935 28 724 1.22E-117 T 28-03-2018 SmaCSM2_RS11420 ece7d689da59257c055cab06c61955c8 724 Gene3D G3DSA:2.170.130.10 23 163 2.5E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11420 ece7d689da59257c055cab06c61955c8 724 Gene3D G3DSA:2.40.170.20 164 724 5.6E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS07565 44caf6c0c2a783ce5a55c5994cb84e65 254 Pfam PF13462 Thioredoxin 65 204 7.2E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07565 44caf6c0c2a783ce5a55c5994cb84e65 254 SUPERFAMILY SSF52833 26 229 1.08E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07565 44caf6c0c2a783ce5a55c5994cb84e65 254 Gene3D G3DSA:3.40.30.10 64 238 3.7E-26 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82714 182 265 1.57E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:3.30.2090.10 180 267 2.9E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:3.30.2090.10 710 794 6.8E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82693 40 134 2.88E-23 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82866 290 489 6.67E-47 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82714 712 791 5.62E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.7E-61 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82693 135 181 7.06E-21 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82693 268 324 7.06E-21 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:3.30.70.1430 560 652 2.3E-5 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82693 557 649 4.19E-5 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:1.20.1640.10 820 1032 7.8E-27 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 SUPERFAMILY SSF82866 795 1015 4.71E-39 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Pfam PF00873 AcrB/AcrD/AcrF family 6 1014 2.1E-284 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:3.30.70.1430 40 142 7.8E-26 T 28-03-2018 SmaCSM2_RS19550 f9cc2a50f6214a06474905c67fb8e0d6 1040 Gene3D G3DSA:1.20.1640.10 268 491 4.5E-47 T 28-03-2018 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 Gene3D G3DSA:3.30.2340.10 165 299 1.5E-34 T 28-03-2018 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 74 87 - T 28-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 2 339 28.628 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 SUPERFAMILY SSF55120 5 334 5.04E-91 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 165 3.2E-41 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS08050 f2200ec6da11397278e76738ca465e28 343 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 182 334 3.7E-19 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS00455 0630bf3f258399f45aa8b191856959de 666 Pfam PF05569 BlaR1 peptidase M56 15 304 3.8E-48 T 28-03-2018 IPR008756 Peptidase M56 SmaCSM2_RS00455 0630bf3f258399f45aa8b191856959de 666 Gene3D G3DSA:1.20.140.50 333 662 6.2E-4 T 28-03-2018 SmaCSM2_RS10200 4b51dec3842adc8fd78f7fef3367f484 125 Pfam PF00072 Response regulator receiver domain 6 114 5.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10200 4b51dec3842adc8fd78f7fef3367f484 125 SUPERFAMILY SSF52172 1 118 4.27E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10200 4b51dec3842adc8fd78f7fef3367f484 125 Gene3D G3DSA:3.40.50.2300 1 125 2.9E-27 T 28-03-2018 SmaCSM2_RS10200 4b51dec3842adc8fd78f7fef3367f484 125 SMART SM00448 4 117 5.7E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07905 13850c203e5e41f2dfad2b63fc486142 146 Gene3D G3DSA:1.10.490.10 2 131 8.3E-22 T 28-03-2018 SmaCSM2_RS07905 13850c203e5e41f2dfad2b63fc486142 146 Pfam PF01152 Bacterial-like globin 18 102 8.1E-7 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 SmaCSM2_RS07905 13850c203e5e41f2dfad2b63fc486142 146 SUPERFAMILY SSF46458 16 123 1.51E-25 T 28-03-2018 IPR009050 Globin-like SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 SUPERFAMILY SSF46626 39 131 1.45E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 Pfam PF00034 Cytochrome c 39 130 2.5E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 Gene3D G3DSA:1.10.760.10 7 131 8.5E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 86 102 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 105 115 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 121 129 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 43 50 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 56 71 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS00830 7407d4d5087f052c6986314a7ad7611b 133 PRINTS PR00604 Class IA and IB cytochrome C signature 72 82 1.8E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 7 318 48.189 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 Gene3D G3DSA:3.40.50.2020 4 161 2.9E-65 T 28-03-2018 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 SMART SM01400 7 124 2.8E-70 T 28-03-2018 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 Gene3D G3DSA:3.40.50.2020 162 319 4.3E-46 T 28-03-2018 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 317 2.6E-116 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 1.0E-45 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 317 2.5E-30 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SmaCSM2_RS03835 26e8beaac8102791f9001f18c98efbdf 319 SUPERFAMILY SSF53271 72 307 2.32E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 292 362 2.3E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 PRINTS PR00406 Cytochrome B5 reductase signature 243 251 1.7E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 PRINTS PR00406 Cytochrome B5 reductase signature 153 172 1.7E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 PRINTS PR00406 Cytochrome B5 reductase signature 76 87 1.7E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 PRINTS PR00406 Cytochrome B5 reductase signature 97 104 1.7E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Pfam PF00970 Oxidoreductase FAD-binding domain 67 145 6.0E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 SUPERFAMILY SSF54292 267 369 9.18E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 SUPERFAMILY SSF52343 144 273 1.7E-27 T 28-03-2018 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Gene3D G3DSA:2.40.30.10 47 142 3.0E-14 T 28-03-2018 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Pfam PF00175 Oxidoreductase NAD-binding domain 154 257 5.0E-13 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Gene3D G3DSA:3.40.50.80 143 271 8.3E-26 T 28-03-2018 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 SUPERFAMILY SSF63380 43 146 2.92E-17 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS12560 1aa87369fec6cd38c87473dc5a124994 369 Gene3D G3DSA:3.10.20.30 272 368 1.9E-16 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 521 55.457 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 SUPERFAMILY SSF54810 401 521 1.96E-49 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Pfam PF00958 GMP synthase C terminal domain 429 520 1.3E-42 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 200 1.2E-75 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Pfam PF02540 NAD synthase 214 298 1.5E-8 T 28-03-2018 IPR022310 NAD/GMP synthase SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 SUPERFAMILY SSF52402 193 415 1.9E-58 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.4E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 2.4E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 2.4E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 SUPERFAMILY SSF52317 4 201 1.45E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Gene3D G3DSA:3.30.300.10 397 521 3.3E-52 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00097 Anthranilate synthase component II signature 53 62 2.7E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00097 Anthranilate synthase component II signature 80 91 2.7E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00097 Anthranilate synthase component II signature 173 186 2.7E-6 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.2E-7 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 1.2E-7 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 1.2E-7 T 28-03-2018 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Gene3D G3DSA:3.40.50.880 4 217 1.5E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 521 4.2E-150 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Gene3D G3DSA:3.40.50.620 218 396 9.4E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS09095 758034433312fa3ab74a9c125fcbcef5 521 Pfam PF00117 Glutamine amidotransferase class-I 11 196 2.2E-40 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS15905 506762846cb153f7d724541ee351f170 335 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 3 298 2.5E-81 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS15905 506762846cb153f7d724541ee351f170 335 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 1 332 46.74 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS15905 506762846cb153f7d724541ee351f170 335 Gene3D G3DSA:3.20.20.300 1 306 6.0E-82 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS15905 506762846cb153f7d724541ee351f170 335 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 233 250 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SmaCSM2_RS15905 506762846cb153f7d724541ee351f170 335 SUPERFAMILY SSF51445 1 298 3.58E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 254 454 1.1E-47 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Gene3D G3DSA:2.40.50.100 2 57 7.5E-11 T 28-03-2018 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 SUPERFAMILY SSF47005 157 196 7.59E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Gene3D G3DSA:4.10.320.10 154 202 7.1E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Pfam PF00364 Biotin-requiring enzyme 6 77 5.9E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 SUPERFAMILY SSF51230 4 87 9.29E-23 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 SUPERFAMILY SSF52777 244 458 2.76E-52 T 28-03-2018 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Gene3D G3DSA:3.30.559.10 235 458 5.8E-47 T 28-03-2018 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Pfam PF02817 e3 binding domain 157 191 2.3E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS19840 3f86f2c21208fa684aa52e45f5bdab7e 462 Gene3D G3DSA:3.90.1170.30 58 153 0.011 T 28-03-2018 SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 Pfam PF13746 4Fe-4S dicluster domain 176 212 1.0E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 Pfam PF13746 4Fe-4S dicluster domain 257 314 3.0E-16 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 Pfam PF12801 4Fe-4S binding domain 68 103 2.9E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 Gene3D G3DSA:1.10.1060.10 179 270 3.6E-7 T 28-03-2018 SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 262 273 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 Gene3D G3DSA:3.30.70.20 271 304 0.0017 T 28-03-2018 SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 SUPERFAMILY SSF54862 77 97 8.79E-19 T 28-03-2018 SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 SUPERFAMILY SSF54862 153 208 8.79E-19 T 28-03-2018 SmaCSM2_RS07895 b42827c0b8d8be24f76b7ca712fad57c 349 SUPERFAMILY SSF54862 262 331 8.79E-19 T 28-03-2018 SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 Gene3D G3DSA:1.20.1250.20 4 196 3.5E-27 T 28-03-2018 SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 Gene3D G3DSA:1.20.1250.20 257 464 3.6E-22 T 28-03-2018 SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 SUPERFAMILY SSF103473 246 458 7.72E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 SUPERFAMILY SSF103473 3 192 7.72E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS03680 2e269b741b868419302d30afca8a1091 472 Pfam PF07690 Major Facilitator Superfamily 15 408 6.7E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS16595 78d7e86ae35528a1c10465e7f6d7206d 141 SMART SM00448 10 120 3.0E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16595 78d7e86ae35528a1c10465e7f6d7206d 141 SUPERFAMILY SSF52172 10 126 1.24E-24 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16595 78d7e86ae35528a1c10465e7f6d7206d 141 Gene3D G3DSA:3.40.50.2300 8 134 6.5E-26 T 28-03-2018 SmaCSM2_RS16595 78d7e86ae35528a1c10465e7f6d7206d 141 Pfam PF00072 Response regulator receiver domain 12 121 7.6E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10160 649ee96a293e6fed1b2a6038b920bbc7 155 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 139 1.6E-23 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 SmaCSM2_RS10160 649ee96a293e6fed1b2a6038b920bbc7 155 Pfam PF02050 Flagellar FliJ protein 19 137 2.9E-23 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 SUPERFAMILY SSF56935 509 658 6.41E-91 T 28-03-2018 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 SUPERFAMILY SSF56935 392 456 6.41E-91 T 28-03-2018 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 SUPERFAMILY SSF56935 312 360 6.41E-91 T 28-03-2018 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 SUPERFAMILY SSF56935 702 980 6.41E-91 T 28-03-2018 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 SUPERFAMILY SSF56935 41 233 6.41E-91 T 28-03-2018 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 Gene3D G3DSA:2.170.130.10 33 175 9.7E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 Gene3D G3DSA:2.40.170.20 178 980 3.5E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 Pfam PF00593 TonB dependent receptor 401 977 1.2E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04310 78a7ce1ae11737953019e6935a0aad36 980 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 168 3.4E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10495 044371853590bb65d2a126dd1a9cfec3 253 Gene3D G3DSA:3.40.50.300 1 242 7.5E-57 T 28-03-2018 SmaCSM2_RS10495 044371853590bb65d2a126dd1a9cfec3 253 SMART SM00382 29 213 8.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10495 044371853590bb65d2a126dd1a9cfec3 253 SUPERFAMILY SSF52540 4 232 5.95E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10495 044371853590bb65d2a126dd1a9cfec3 253 Pfam PF00005 ABC transporter 20 165 6.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 Gene3D G3DSA:2.40.30.60 7 95 2.3E-20 T 28-03-2018 IPR002676 RimM protein GO:0006364 SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 7 170 23.921 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 Pfam PF05239 PRC-barrel domain 98 164 1.6E-5 T 28-03-2018 IPR027275 PRC-barrel domain SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 Gene3D G3DSA:2.30.30.240 97 165 3.4E-20 T 28-03-2018 SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 SUPERFAMILY SSF50447 8 95 2.15E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 8 169 4.7E-52 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 SUPERFAMILY SSF50346 101 170 1.46E-18 T 28-03-2018 IPR011033 PRC-barrel-like SmaCSM2_RS06070 dea3442178bad58acd87555cee2db002 170 Pfam PF01782 RimM N-terminal domain 10 92 3.4E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 SmaCSM2_RS02225 2a841c6e7ada552aa6a132c5af8ad9ac 457 Pfam PF00324 Amino acid permease 19 454 4.1E-109 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SmaCSM2_RS02225 2a841c6e7ada552aa6a132c5af8ad9ac 457 PIRSF PIRSF006060 1 455 1.6E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS02225 2a841c6e7ada552aa6a132c5af8ad9ac 457 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 Gene3D G3DSA:3.30.1330.20 217 327 3.7E-43 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 SMART SM00864 15 207 4.9E-112 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 SUPERFAMILY SSF55307 206 319 5.04E-42 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 Pfam PF12327 FtsZ family, C-terminal domain 224 318 3.9E-37 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 174 8.6E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 PRINTS PR00423 Cell division protein FtsZ signature 191 213 3.7E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 PRINTS PR00423 Cell division protein FtsZ signature 128 149 3.7E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 PRINTS PR00423 Cell division protein FtsZ signature 214 235 3.7E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 PRINTS PR00423 Cell division protein FtsZ signature 100 120 3.7E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 327 3.3E-129 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 SMART SM00865 209 327 1.9E-52 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 349 37.375 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 ProSitePatterns PS01135 FtsZ protein signature 2. 99 120 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 Gene3D G3DSA:3.40.50.1440 7 216 2.9E-43 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS03285 20431be17053310ba8a2255170a02100 411 SUPERFAMILY SSF52490 15 210 2.35E-69 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SmaCSM2_RS04580 d03d7f0e3e78a64e891ee3dc596a3b4c 264 Gene3D G3DSA:3.90.1210.10 46 113 4.1E-11 T 28-03-2018 SmaCSM2_RS04580 d03d7f0e3e78a64e891ee3dc596a3b4c 264 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 221 2.6E-24 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SmaCSM2_RS04580 d03d7f0e3e78a64e891ee3dc596a3b4c 264 SMART SM00858 48 112 4.9E-9 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SmaCSM2_RS04580 d03d7f0e3e78a64e891ee3dc596a3b4c 264 Pfam PF08666 SAF domain 49 111 5.8E-8 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SmaCSM2_RS04580 d03d7f0e3e78a64e891ee3dc596a3b4c 264 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 13 227 5.6E-47 T 28-03-2018 IPR017592 Pilus assembly, Flp-type CpaB SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SMART SM00387 187 303 9.2E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Gene3D G3DSA:3.40.50.2300 455 592 1.4E-42 T 28-03-2018 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 228 242 7.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 281 7.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 300 7.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 246 256 7.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SMART SM00388 75 140 1.2E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Pfam PF01627 Hpt domain 643 720 3.1E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SUPERFAMILY SSF47226 618 733 3.79E-24 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Pfam PF00512 His Kinase A (phospho-acceptor) domain 75 139 2.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Gene3D G3DSA:1.10.287.130 58 136 2.2E-19 T 28-03-2018 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SMART SM00448 458 574 2.0E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Gene3D G3DSA:1.20.120.160 615 731 1.2E-18 T 28-03-2018 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Pfam PF00072 Response regulator receiver domain 460 574 8.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SMART SM00073 633 730 0.005 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 187 301 5.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 Gene3D G3DSA:3.30.565.10 144 307 1.2E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SUPERFAMILY SSF55874 129 302 1.96E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SUPERFAMILY SSF47384 58 140 1.33E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS19620 cdc46020b176874b75ca3e8f08a187e1 739 SUPERFAMILY SSF52172 458 588 5.41E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01980 cf517b3852ef5fa20a17c28ed4a5d306 454 SMART SM01150 12 408 2.0E-229 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 SmaCSM2_RS01980 cf517b3852ef5fa20a17c28ed4a5d306 454 Pfam PF07063 Domain of unknown function (DUF1338) 11 408 7.6E-120 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 SmaCSM2_RS00130 b47b8f597ecb672afabfe4cb1c892119 444 SUPERFAMILY SSF103473 9 404 1.31E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS00130 b47b8f597ecb672afabfe4cb1c892119 444 Gene3D G3DSA:1.20.1250.20 201 413 2.1E-20 T 28-03-2018 SmaCSM2_RS00130 b47b8f597ecb672afabfe4cb1c892119 444 Pfam PF07690 Major Facilitator Superfamily 222 410 3.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS00130 b47b8f597ecb672afabfe4cb1c892119 444 Gene3D G3DSA:1.20.1250.20 1 190 1.9E-12 T 28-03-2018 SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 Gene3D G3DSA:1.10.287.90 30 115 7.1E-19 T 28-03-2018 SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 SUPERFAMILY SSF49503 121 283 7.44E-42 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 Pfam PF06481 COX Aromatic Rich Motif 240 287 2.1E-12 T 28-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 Gene3D G3DSA:2.60.40.420 116 283 3.1E-44 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 PIRSF PIRSF000292 5 314 4.1E-126 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 SUPERFAMILY SSF81464 32 119 5.56E-23 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06000 8ec3032a8debb5997a57987d1c391b01 346 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 17 239 2.1E-106 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 SmaCSM2_RS10390 af14330a5b497971e9bcb071991243c9 270 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 8 250 4.5E-67 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SmaCSM2_RS10390 af14330a5b497971e9bcb071991243c9 270 Gene3D G3DSA:3.90.1200.10 78 269 1.4E-9 T 28-03-2018 SmaCSM2_RS10390 af14330a5b497971e9bcb071991243c9 270 SUPERFAMILY SSF56112 23 249 1.02E-25 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS20675 ead2730cd018f4b22a06073da970ffd8 320 Gene3D G3DSA:3.40.50.1100 141 315 1.7E-39 T 28-03-2018 SmaCSM2_RS20675 ead2730cd018f4b22a06073da970ffd8 320 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SmaCSM2_RS20675 ead2730cd018f4b22a06073da970ffd8 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 307 4.1E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS20675 ead2730cd018f4b22a06073da970ffd8 320 SUPERFAMILY SSF53686 10 314 3.01E-81 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS20675 ead2730cd018f4b22a06073da970ffd8 320 Gene3D G3DSA:3.40.50.1100 34 140 8.1E-28 T 28-03-2018 SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 412 3.2E-71 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 SMART SM00382 323 517 2.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 SMART SM00962 324 515 7.5E-51 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 Pfam PF00448 SRP54-type protein, GTPase domain 326 513 6.6E-37 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 SUPERFAMILY SSF52540 321 509 2.53E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10100 349dc5f8d3e9358e3be1837798e137ec 533 Gene3D G3DSA:3.40.50.300 321 515 4.5E-27 T 28-03-2018 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 SUPERFAMILY SSF52172 1 128 2.85E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 SUPERFAMILY SSF46894 124 222 5.1E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 Pfam PF00072 Response regulator receiver domain 4 113 1.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 SMART SM00448 1 113 6.1E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 Gene3D G3DSA:3.40.50.2300 1 121 7.3E-31 T 28-03-2018 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 SMART SM00862 147 221 1.0E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 4.8E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS16025 c597e38f7a98645b82bb6cde49fd7ebd 237 Gene3D G3DSA:1.10.10.10 122 228 7.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 9.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 SUPERFAMILY SSF51735 7 250 3.85E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 Pfam PF00106 short chain dehydrogenase 14 203 2.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS04905 a846940f64bfb0aa6abd7b0248e9006a 293 Gene3D G3DSA:3.40.50.720 6 287 4.1E-41 T 28-03-2018 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SMART SM00260 473 610 8.5E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SUPERFAMILY SSF50341 480 609 1.27E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 435 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 478 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 480 5.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:3.30.565.10 296 481 2.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:2.40.50.180 506 556 1.3E-7 T 28-03-2018 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:1.10.287.560 233 294 1.1E-16 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Pfam PF01584 CheW-like domain 487 609 2.6E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SUPERFAMILY SSF55874 296 479 1.83E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 234 292 2.2E-11 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SUPERFAMILY SSF47226 6 121 1.07E-28 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:1.20.120.160 2 145 1.4E-29 T 28-03-2018 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:2.30.30.40 482 505 0.033 T 28-03-2018 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Gene3D G3DSA:2.30.30.40 557 609 7.5E-19 T 28-03-2018 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 Pfam PF01627 Hpt domain 10 105 1.3E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SMART SM01231 233 293 1.1E-16 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SUPERFAMILY SSF47384 234 294 6.67E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SMART SM00073 5 102 1.0E-19 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10075 3e4cfa3582092d96da69545be1af82ee 614 SMART SM00387 338 481 1.5E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 Gene3D G3DSA:2.40.50.40 136 202 6.5E-14 T 28-03-2018 SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 Pfam PF00072 Response regulator receiver domain 3 112 7.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 SUPERFAMILY SSF52172 2 123 3.42E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 SMART SM00448 1 112 1.1E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 Pfam PF04397 LytTr DNA-binding domain 146 240 8.8E-25 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 SMART SM00850 144 241 6.0E-28 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS18800 e0f87ac1c1d0e1360a46f412fe6982cf 243 Gene3D G3DSA:3.40.50.2300 1 135 5.0E-35 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82866 832 1028 1.44E-45 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82866 296 497 1.96E-48 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 809 858 3.66E-27 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 665 715 3.66E-27 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 563 664 1.52E-27 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:3.30.70.1430 565 664 1.8E-18 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82714 182 271 3.14E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 135 182 1.41E-22 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 274 330 1.41E-22 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:1.20.1640.10 817 1031 1.0E-37 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:1.20.1640.10 273 499 2.2E-44 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:3.30.70.1440 665 762 9.8E-17 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:3.30.2090.10 180 272 4.7E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 617 631 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.7E-99 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Gene3D G3DSA:3.30.70.1430 38 140 1.0E-29 T 28-03-2018 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82714 716 807 2.22E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 Pfam PF00873 AcrB/AcrD/AcrF family 1 1028 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14000 e7a178ee8c8ec7a783d2a1fafd9ec6a7 1057 SUPERFAMILY SSF82693 38 132 3.19E-28 T 28-03-2018 SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 Pfam PF10459 Peptidase S46 23 711 5.5E-228 T 28-03-2018 IPR019500 Peptidase S46 GO:0008239|GO:0070009 SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 Gene3D G3DSA:2.40.10.10 52 192 1.2E-4 T 28-03-2018 SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 SUPERFAMILY SSF50494 177 286 4.51E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 SUPERFAMILY SSF50494 637 697 4.51E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 SUPERFAMILY SSF50494 35 99 4.51E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS21405 9ab34c990fb4cc55e185a6aba625b9b7 715 Gene3D G3DSA:2.40.10.10 253 700 1.5E-15 T 28-03-2018 SmaCSM2_RS07635 ae4b2da3d7807d65796a773320308340 241 TIGRFAM TIGR03759 conj_TIGR03759: integrating conjugative element protein, PFL_4693 family 45 238 4.3E-84 T 28-03-2018 IPR022293 Integrating conjugative element protein, PFL4693 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PIRSF PIRSF000350 1 474 6.1E-74 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 475 4.5E-151 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 Gene3D G3DSA:3.30.390.30 346 475 4.2E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 433 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 460 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 374 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 8.2E-72 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 SUPERFAMILY SSF51905 1 347 2.29E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 3.6E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 3.6E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.6E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.6E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 3.6E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 Gene3D G3DSA:3.40.50.720 174 345 6.2E-35 T 28-03-2018 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 Gene3D G3DSA:3.50.50.60 1 173 2.3E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 SUPERFAMILY SSF55424 354 475 1.2E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 465 9.9E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 338 1.9E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS14130 bd5a59378c06ce1d774f0f0c8d0578ed 478 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 46 56 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 169 2.7E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 Pfam PF00593 TonB dependent receptor 374 874 5.7E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 SUPERFAMILY SSF56935 391 875 4.07E-107 T 28-03-2018 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 SUPERFAMILY SSF56935 39 237 4.07E-107 T 28-03-2018 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 SUPERFAMILY SSF56935 306 354 4.07E-107 T 28-03-2018 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 Gene3D G3DSA:2.40.170.20 171 875 1.2E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12615 526525e7ef993d0bacffa303a6c4a37d 875 Gene3D G3DSA:2.170.130.10 48 170 2.5E-31 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 170 192 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 63 83 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 93 118 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 353 372 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 380 400 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 PRINTS PR00173 Glutamate-aspartate symporter signature 318 344 4.3E-34 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 Pfam PF00375 Sodium:dicarboxylate symporter family 13 425 1.1E-109 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 SUPERFAMILY SSF118215 13 425 1.96E-100 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17235 208721ead26222710764af599467ad30 439 Gene3D G3DSA:1.10.3860.10 4 430 1.0E-109 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 Gene3D G3DSA:3.20.20.140 94 385 2.2E-33 T 28-03-2018 SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 SUPERFAMILY SSF51338 327 449 1.06E-25 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 SUPERFAMILY SSF51556 79 368 1.48E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 SUPERFAMILY SSF51338 24 94 2.54E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 Gene3D G3DSA:2.30.40.10 14 93 1.5E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20330 2c1b017f0c0b339b5de60ccdc8f676a7 452 Pfam PF01979 Amidohydrolase family 76 419 3.5E-31 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 PRINTS PR00338 Transcription termination factor NUSG signature 161 177 9.2E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 PRINTS PR00338 Transcription termination factor NUSG signature 143 158 9.2E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 PRINTS PR00338 Transcription termination factor NUSG signature 56 68 9.2E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 SUPERFAMILY SSF50104 129 184 1.1E-18 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 SMART SM00738 1 119 8.3E-46 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 ProSitePatterns PS01014 Transcription termination factor nusG signature. 168 177 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 Pfam PF02357 Transcription termination factor nusG 2 116 6.3E-23 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 4 184 7.7E-62 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 Gene3D G3DSA:2.30.30.30 126 185 2.3E-20 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 1 185 23.887 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 SMART SM00739 131 158 1.7E-5 T 28-03-2018 IPR005824 KOW SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 Gene3D G3DSA:3.30.70.940 1 123 6.3E-37 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 SUPERFAMILY SSF82679 1 121 9.29E-36 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SmaCSM2_RS03925 3a7647e5a32299eaa95466e5caa6f371 186 Pfam PF00467 KOW motif 134 166 1.6E-7 T 28-03-2018 IPR005824 KOW SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 SMART SM00840 339 398 8.5E-11 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 23 313 2.3E-110 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 456 35.987 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 SUPERFAMILY SSF47323 317 455 3.66E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 SUPERFAMILY SSF52374 4 314 1.08E-84 T 28-03-2018 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 455 4.5E-143 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 Gene3D G3DSA:3.40.50.620 1 306 1.4E-79 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 Gene3D G3DSA:1.20.120.640 307 435 3.5E-10 T 28-03-2018 SmaCSM2_RS14640 70a18f28d33af786672bdf84666e7200 458 Pfam PF09190 DALR domain 340 398 2.4E-10 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 287 4.3E-17 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 Gene3D G3DSA:2.40.50.100 204 355 2.0E-6 T 28-03-2018 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 55 75 4.9E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 327 342 4.9E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 SUPERFAMILY SSF111369 185 284 2.62E-13 T 28-03-2018 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 Gene3D G3DSA:2.40.50.100 45 113 2.7E-18 T 28-03-2018 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 SUPERFAMILY SSF111369 46 119 1.27E-10 T 28-03-2018 SmaCSM2_RS18000 b463768cf8e198ee38c930f1f68e7e79 360 Gene3D G3DSA:1.10.287.470 114 177 6.6E-6 T 28-03-2018 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 484 2.7E-166 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 SUPERFAMILY SSF56322 16 484 4.06E-155 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 Gene3D G3DSA:3.60.120.10 14 486 2.4E-163 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 PRINTS PR00095 Anthranilate synthase component I signature 433 447 8.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 PRINTS PR00095 Anthranilate synthase component I signature 418 432 8.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 PRINTS PR00095 Anthranilate synthase component I signature 324 337 8.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 PRINTS PR00095 Anthranilate synthase component I signature 338 351 8.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 Pfam PF04715 Anthranilate synthase component I, N terminal region 27 170 6.3E-26 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19710 386f798de6dc44a9b64cdbb460705715 491 Pfam PF00425 chorismate binding enzyme 223 476 4.8E-99 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Gene3D G3DSA:3.40.50.800 460 567 2.5E-26 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 39.32 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 SUPERFAMILY SSF55681 10 237 2.58E-98 T 28-03-2018 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 SUPERFAMILY SSF55681 406 477 2.58E-98 T 28-03-2018 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 1.2E-217 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Pfam PF03129 Anticodon binding domain 474 566 1.0E-14 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 SUPERFAMILY SSF52954 463 566 2.57E-25 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Pfam PF04073 Aminoacyl-tRNA editing domain 256 379 6.1E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Gene3D G3DSA:3.30.930.10 11 459 2.4E-94 T 28-03-2018 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 SUPERFAMILY SSF55826 220 390 6.67E-36 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.4E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.4E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.4E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.4E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SmaCSM2_RS02855 0c20742053c71db7bde2752977012543 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 458 1.8E-42 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Gene3D G3DSA:3.40.50.300 5 151 2.5E-22 T 28-03-2018 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Gene3D G3DSA:1.10.8.60 152 230 3.6E-15 T 28-03-2018 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Pfam PF16193 AAA C-terminal domain 181 257 3.8E-18 T 28-03-2018 IPR032423 AAA C-terminal domain SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 SUPERFAMILY SSF48019 242 424 8.5E-72 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 SUPERFAMILY SSF52540 11 226 8.05E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Gene3D G3DSA:1.20.272.10 242 336 2.5E-35 T 28-03-2018 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Pfam PF12002 MgsA AAA+ ATPase C terminal 258 424 8.3E-67 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Gene3D G3DSA:1.10.3710.10 338 435 3.9E-35 T 28-03-2018 SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 SMART SM00382 46 163 3.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS07495 cb8cba65dc276a90227a39f130efcbaf 437 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 136 2.6E-13 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS15850 e3a44692c7c8e788258e0a6926fb5044 136 Gene3D G3DSA:1.20.120.20 21 132 2.5E-6 T 28-03-2018 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 339 6.4E-146 T 28-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 SMART SM00829 12 337 0.002 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 Pfam PF00107 Zinc-binding dehydrogenase 174 301 4.3E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 339 58.238 T 28-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 135 2.7E-33 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 Gene3D G3DSA:3.90.180.10 1 158 7.8E-47 T 28-03-2018 SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 SUPERFAMILY SSF51735 141 304 9.32E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 SUPERFAMILY SSF50129 1 173 8.07E-56 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS04245 18c231d89162133b886583c3b1b05f4b 340 Gene3D G3DSA:3.40.50.10730 159 303 1.5E-23 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Pfam PF13623 SurA N-terminal domain 2 157 3.1E-23 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 SUPERFAMILY SSF109998 222 255 7.06E-16 T 28-03-2018 IPR027304 Trigger factor/SurA domain SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 SUPERFAMILY SSF109998 68 189 7.06E-16 T 28-03-2018 IPR027304 Trigger factor/SurA domain SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Gene3D G3DSA:3.10.50.40 279 405 1.4E-38 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Gene3D G3DSA:3.10.50.40 411 517 4.6E-7 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Gene3D G3DSA:3.10.50.40 518 625 8.6E-5 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 320 341 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 SUPERFAMILY SSF54534 284 384 4.32E-31 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Gene3D G3DSA:1.10.4030.10 66 187 4.3E-11 T 28-03-2018 SmaCSM2_RS04465 a0f13ff65c5be16eb2093290292a6684 651 Pfam PF13616 PPIC-type PPIASE domain 282 381 7.1E-30 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 397 4.6E-33 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:1.10.287.610 2 67 2.8E-24 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF12826 Helix-hairpin-helix motif 567 630 3.5E-15 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 7 318 2.8E-121 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:1.10.150.20 564 628 1.4E-21 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:3.40.50.10190 629 821 1.8E-23 T 28-03-2018 IPR001357 BRCT domain SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SUPERFAMILY SSF50249 318 400 2.23E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SMART SM00532 4 448 4.6E-258 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Hamap MF_01588 DNA ligase [ligA]. 3 817 52.81 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:1.10.150.20 432 562 3.0E-25 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 745 815 2.9E-13 T 28-03-2018 IPR001357 BRCT domain SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SMART SM00292 743 820 2.9E-14 T 28-03-2018 IPR001357 BRCT domain SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:2.40.50.140 317 390 3.3E-32 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Gene3D G3DSA:3.30.470.30 119 252 1.4E-51 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 PIRSF PIRSF001604 648 821 2.4E-22 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 PIRSF PIRSF001604 1 654 1.5E-205 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SUPERFAMILY SSF47781 404 490 1.04E-51 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SUPERFAMILY SSF47781 548 637 1.04E-51 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF14520 Helix-hairpin-helix domain 446 484 0.005 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SUPERFAMILY SSF52113 744 818 6.17E-19 T 28-03-2018 IPR001357 BRCT domain SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 407 434 1.7E-11 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 SUPERFAMILY SSF56091 6 316 2.47E-114 T 28-03-2018 SmaCSM2_RS13870 92c648c3a98d9a783e3d483a62736f36 821 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 12 490 5.0E-192 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SmaCSM2_RS05115 79e8d36fab317a72a54fa275a7e14bad 191 Gene3D G3DSA:2.60.450.10 88 188 0.0023 T 28-03-2018 SmaCSM2_RS05115 79e8d36fab317a72a54fa275a7e14bad 191 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 16 187 8.9E-34 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related SmaCSM2_RS05115 79e8d36fab317a72a54fa275a7e14bad 191 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 11 187 2.2E-39 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 SMART SM00387 337 439 3.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 SMART SM00388 238 295 2.4E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 Gene3D G3DSA:3.30.565.10 298 444 1.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 294 1.8E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 437 1.8E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 Gene3D G3DSA:1.10.287.130 228 291 3.5E-8 T 28-03-2018 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 SUPERFAMILY SSF47384 221 295 7.65E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13510 c51d2b670f13704a2aff768eec977894 449 SUPERFAMILY SSF55874 285 437 1.17E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Gene3D G3DSA:3.40.50.300 390 668 3.5E-47 T 28-03-2018 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 272 1.4E-67 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Pfam PF13361 UvrD-like helicase C-terminal domain 278 624 1.0E-77 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 TIGRFAM TIGR01075 uvrD: DNA helicase II 6 727 0.0 T 28-03-2018 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 SUPERFAMILY SSF52540 6 650 8.93E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Gene3D G3DSA:3.40.50.300 4 149 7.0E-26 T 28-03-2018 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Gene3D G3DSA:3.40.50.300 150 283 1.0E-31 T 28-03-2018 SmaCSM2_RS21255 4d61e0414d02f3689bc6c5f4a8923c08 730 Gene3D G3DSA:3.40.50.300 284 385 7.2E-28 T 28-03-2018 SmaCSM2_RS07450 aa529540e9a02e5fa19991269c9d3c0a 135 Pfam PF12680 SnoaL-like domain 8 117 2.7E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SmaCSM2_RS07450 aa529540e9a02e5fa19991269c9d3c0a 135 SUPERFAMILY SSF54427 1 132 2.25E-28 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS07450 aa529540e9a02e5fa19991269c9d3c0a 135 Gene3D G3DSA:3.10.450.50 2 132 4.1E-25 T 28-03-2018 SmaCSM2_RS07450 aa529540e9a02e5fa19991269c9d3c0a 135 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 5 132 6.3E-40 T 28-03-2018 IPR011721 Conserved hypothetical protein CHP02096 SmaCSM2_RS14170 868389e021986d33362b424a2b5fa710 186 Pfam PF03358 NADPH-dependent FMN reductase 5 148 2.0E-38 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS14170 868389e021986d33362b424a2b5fa710 186 Gene3D G3DSA:3.40.50.360 1 184 4.0E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS14170 868389e021986d33362b424a2b5fa710 186 SUPERFAMILY SSF52218 4 175 4.19E-49 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Gene3D G3DSA:1.10.1050.10 1 103 2.3E-42 T 28-03-2018 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Pfam PF01479 S4 domain 99 145 6.9E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Gene3D G3DSA:3.10.290.10 104 146 1.5E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Gene3D G3DSA:1.10.1050.10 147 209 1.3E-13 T 28-03-2018 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 209 2.8E-76 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 SMART SM00363 98 162 1.3E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 SMART SM01390 3 97 2.3E-46 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 SUPERFAMILY SSF55174 3 209 5.63E-65 T 28-03-2018 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 4.9E-31 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SmaCSM2_RS04105 5eb2fd3165072850f41942594d5c702a 209 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 209 34.591 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 Pfam PF02222 ATP-grasp domain 108 279 1.1E-56 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 355 2.3E-109 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 SUPERFAMILY SSF56059 99 300 1.31E-62 T 28-03-2018 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 Gene3D G3DSA:3.30.470.20 182 377 5.1E-36 T 28-03-2018 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 Gene3D G3DSA:3.40.50.20 3 88 4.3E-21 T 28-03-2018 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 SUPERFAMILY SSF51246 304 370 5.26E-14 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 Gene3D G3DSA:3.30.1490.20 115 179 1.8E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 SUPERFAMILY SSF52440 4 96 4.6E-21 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS07185 ee88bc60fbf6a164fcc63a0d48cc9085 382 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 4 352 40.38 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SmaCSM2_RS12385 6dd6e0f91f41077f6c7d5e38c7748680 242 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 10 225 3.1E-116 T 28-03-2018 IPR014063 Arsenate resistance ArsH SmaCSM2_RS12385 6dd6e0f91f41077f6c7d5e38c7748680 242 SUPERFAMILY SSF52218 11 226 1.75E-60 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS12385 6dd6e0f91f41077f6c7d5e38c7748680 242 Pfam PF03358 NADPH-dependent FMN reductase 34 179 5.4E-27 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS12385 6dd6e0f91f41077f6c7d5e38c7748680 242 Gene3D G3DSA:3.40.50.360 22 225 1.3E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS01230 e87141cf6ecbd44297c2516a475af5be 219 Pfam PF08813 Phage tail tube protein, TTP 53 210 5.4E-42 T 28-03-2018 IPR014918 Phage tail tube protein 3 SmaCSM2_RS05120 de904191686553434bffe80295fab316 182 Gene3D G3DSA:3.40.50.1000 14 180 2.7E-27 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS05120 de904191686553434bffe80295fab316 182 SUPERFAMILY SSF56784 18 176 1.03E-36 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS05120 de904191686553434bffe80295fab316 182 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 21 171 4.1E-36 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS05120 de904191686553434bffe80295fab316 182 PIRSF PIRSF006118 8 181 7.6E-60 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS05120 de904191686553434bffe80295fab316 182 Pfam PF08282 haloacid dehalogenase-like hydrolase 94 153 2.5E-6 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS12010 318ef556d418b64a909a6001f6650670 208 Gene3D G3DSA:3.40.50.300 1 142 1.5E-9 T 28-03-2018 SmaCSM2_RS12010 318ef556d418b64a909a6001f6650670 208 SUPERFAMILY SSF52540 2 158 6.25E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 Pfam PF01464 Transglycosylase SLT domain 108 212 5.6E-22 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 SUPERFAMILY SSF54106 355 398 3.66E-9 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 SUPERFAMILY SSF53955 97 242 7.16E-30 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 Pfam PF01476 LysM domain 356 398 4.5E-11 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 SMART SM00257 355 399 1.6E-10 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 Gene3D G3DSA:1.10.530.10 63 245 2.9E-27 T 28-03-2018 SmaCSM2_RS04470 66a1b394cebab3a193348657ea34f70a 400 Gene3D G3DSA:3.10.350.10 350 400 6.4E-12 T 28-03-2018 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 Gene3D G3DSA:3.10.50.30 76 157 8.7E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 Gene3D G3DSA:1.10.287.180 2 75 1.3E-32 T 28-03-2018 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 4 154 5.7E-57 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 1 155 33.293 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 156 1.6E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 PIRSF PIRSF006092 1 157 2.8E-49 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 5.4E-32 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 16 47 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 SUPERFAMILY SSF46557 4 77 2.35E-29 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SmaCSM2_RS09835 11c20ed87f85c97b0b8050ddabab2980 158 SUPERFAMILY SSF54534 82 156 4.05E-21 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 22 3.3E-7 T 28-03-2018 IPR024973 ESPR domain SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:2.150.10.10 745 881 2.7E-21 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 698 728 3.1E-4 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 964 994 5.7E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 339 382 1.7E-5 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 237 279 1.0E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 603 633 2.5E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 515 559 2.4E-6 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 427 470 2.9E-5 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 858 889 0.014 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:2.150.10.10 473 536 2.5E-5 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:2.150.10.10 369 448 4.6E-5 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:2.150.10.10 100 257 2.5E-32 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:2.150.10.10 882 984 7.5E-5 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:3.30.1300.30 1099 1173 3.5E-15 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 SUPERFAMILY SSF101967 636 724 6.93E-5 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 SUPERFAMILY SSF54523 1077 1173 2.2E-14 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF03895 YadA-like membrane anchor domain 1116 1173 3.3E-14 T 28-03-2018 IPR005594 YadA-like, C-terminal SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF05658 Head domain of trimeric autotransporter adhesin 180 205 2.4E-4 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 261 302 6.7E-5 T 28-03-2018 IPR021793 Major outer membrane lipoprotein Oprl SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 SUPERFAMILY SSF101967 752 879 2.22E-16 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:1.20.5.170 537 601 6.9E-6 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:1.20.5.170 985 1098 3.2E-9 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:1.20.5.170 258 344 9.7E-6 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:1.20.5.170 449 472 2.9E-4 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 Gene3D G3DSA:1.20.5.170 610 700 8.3E-6 T 28-03-2018 SmaCSM2_RS17310 85fc0014dd81e830487b64273fe45c61 1173 SUPERFAMILY SSF101967 121 264 3.01E-25 T 28-03-2018 SmaCSM2_RS06110 b8313d31b9731cb01c56cb6be16a3563 135 Pfam PF01479 S4 domain 11 56 1.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06110 b8313d31b9731cb01c56cb6be16a3563 135 Gene3D G3DSA:3.10.290.10 8 107 6.9E-24 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06110 b8313d31b9731cb01c56cb6be16a3563 135 SMART SM00363 11 72 6.6E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06110 b8313d31b9731cb01c56cb6be16a3563 135 SUPERFAMILY SSF55174 10 102 3.01E-25 T 28-03-2018 SmaCSM2_RS06110 b8313d31b9731cb01c56cb6be16a3563 135 PIRSF PIRSF016821 8 134 1.5E-35 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 SmaCSM2_RS14420 6d8c0e0a61786637e1966640539158c5 99 Pfam PF03795 YCII-related domain 2 95 7.1E-23 T 28-03-2018 IPR005545 YCII-related SmaCSM2_RS14420 6d8c0e0a61786637e1966640539158c5 99 SUPERFAMILY SSF54909 2 97 5.18E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS14420 6d8c0e0a61786637e1966640539158c5 99 Gene3D G3DSA:3.30.70.1060 2 98 4.0E-25 T 28-03-2018 SmaCSM2_RS07770 f1ada004b64a7531700eb75572dcc63a 259 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 12 224 5.7E-88 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 SmaCSM2_RS07770 f1ada004b64a7531700eb75572dcc63a 259 Pfam PF08900 Domain of unknown function (DUF1845) 11 221 4.4E-78 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 SmaCSM2_RS19855 61f87476892a2548c538cb3111a60140 211 SUPERFAMILY SSF51735 1 203 2.1E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS19855 61f87476892a2548c538cb3111a60140 211 Pfam PF08732 HIM1 58 155 1.5E-7 T 28-03-2018 IPR014843 Protein Him1/Fmp52 SmaCSM2_RS19855 61f87476892a2548c538cb3111a60140 211 SMART SM00859 2 105 0.0067 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SmaCSM2_RS19855 61f87476892a2548c538cb3111a60140 211 Gene3D G3DSA:3.40.50.720 1 209 5.4E-15 T 28-03-2018 SmaCSM2_RS05580 d9849db16829ddea4939f8adc45ef453 74 Gene3D G3DSA:1.10.260.40 2 70 2.1E-11 T 28-03-2018 SmaCSM2_RS05580 d9849db16829ddea4939f8adc45ef453 74 SMART SM00530 6 62 1.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS05580 d9849db16829ddea4939f8adc45ef453 74 SUPERFAMILY SSF47413 1 68 7.6E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS05580 d9849db16829ddea4939f8adc45ef453 74 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 67 2.8E-20 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 18 153 3.6E-48 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 Gene3D G3DSA:3.10.420.10 13 162 5.6E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 Pfam PF02556 Preprotein translocase subunit SecB 16 153 5.7E-53 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 Hamap MF_00821 Protein-export protein SecB [secB]. 1 155 32.073 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 SUPERFAMILY SSF54611 19 158 5.45E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 107 129 4.2E-35 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 133 151 4.2E-35 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 23 40 4.2E-35 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS00720 907b9809ae89156f312f42ac897bfd19 172 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 83 103 4.2E-35 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 Pfam PF00593 TonB dependent receptor 256 694 1.2E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 Gene3D G3DSA:2.170.130.10 25 165 1.5E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 154 6.7E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 Gene3D G3DSA:2.40.170.20 168 695 2.4E-72 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 57 695 1.7E-97 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS04925 20cd9a259dc84850b27cf61d18985010 695 SUPERFAMILY SSF56935 26 695 1.45E-127 T 28-03-2018 SmaCSM2_RS10635 5c9a53eea0096afb9bbc9c24a91902b2 128 SUPERFAMILY SSF47413 6 55 8.44E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS10635 5c9a53eea0096afb9bbc9c24a91902b2 128 Gene3D G3DSA:1.10.260.40 5 80 6.2E-7 T 28-03-2018 SmaCSM2_RS10635 5c9a53eea0096afb9bbc9c24a91902b2 128 Pfam PF12472 Phage related protein 65 115 4.6E-8 T 28-03-2018 IPR021096 Vibrio phage VSK, Orf152 SmaCSM2_RS04070 f5f3126637fc6b862fd452f8f03016f4 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 1.4E-35 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04070 f5f3126637fc6b862fd452f8f03016f4 117 Gene3D G3DSA:3.30.420.100 2 117 3.7E-32 T 28-03-2018 SmaCSM2_RS04070 f5f3126637fc6b862fd452f8f03016f4 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 3.9E-35 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04070 f5f3126637fc6b862fd452f8f03016f4 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 24.983 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04070 f5f3126637fc6b862fd452f8f03016f4 117 SUPERFAMILY SSF53137 3 115 5.23E-46 T 28-03-2018 SmaCSM2_RS10655 dd7ff60b43c43be1ec32a3820bf09da8 92 ProDom PD015272 DNA DNA-BINDING SINGLE-STRANDED PHAGE-RELATED HELIX-DESTABILIZING REPLICATION BINDING GPV 3D-STRUCTURE DIRECT 9 80 1.0E-33 T 28-03-2018 IPR003512 Bacteriophage M13, G5P, DNA-binding GO:0003697|GO:0006260 SmaCSM2_RS10655 dd7ff60b43c43be1ec32a3820bf09da8 92 Gene3D G3DSA:2.40.50.140 4 80 8.1E-16 T 28-03-2018 SmaCSM2_RS10655 dd7ff60b43c43be1ec32a3820bf09da8 92 SUPERFAMILY SSF50249 1 81 6.51E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS10655 dd7ff60b43c43be1ec32a3820bf09da8 92 Pfam PF02303 Helix-destabilising protein 18 75 1.5E-9 T 28-03-2018 IPR003512 Bacteriophage M13, G5P, DNA-binding GO:0003697|GO:0006260 SmaCSM2_RS02435 6d564488bfc7ef222c7dc03f20dcb13c 188 Pfam PF11454 Protein of unknown function (DUF3016) 40 177 5.1E-50 T 28-03-2018 IPR021557 Protein of unknown function DUF3016 SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 Pfam PF00990 Diguanylate cyclase, GGDEF domain 384 541 1.5E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 Gene3D G3DSA:3.30.70.270 368 543 9.9E-57 T 28-03-2018 SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 SUPERFAMILY SSF55073 389 543 7.77E-46 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 381 543 1.7E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 SMART SM00267 373 545 3.5E-51 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06450 be9fe6b8a06cd3f373c5a0f95bcc4672 554 Pfam PF07695 7TM diverse intracellular signalling 166 368 4.6E-10 T 28-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 Pfam PF00849 RNA pseudouridylate synthase 109 259 6.3E-27 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 146 160 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 SUPERFAMILY SSF55174 27 79 4.58E-10 T 28-03-2018 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 Gene3D G3DSA:3.30.2350.10 99 324 1.5E-59 T 28-03-2018 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 25 324 2.5E-73 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 Pfam PF01479 S4 domain 28 74 1.7E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 SUPERFAMILY SSF55120 95 323 4.0E-57 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 SMART SM00363 28 90 1.4E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS14365 068d974f71fddb3f4af2522bc2ff78b4 324 Gene3D G3DSA:3.10.290.10 16 85 2.5E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS14805 d01f8babde4f30a75bd3e5f73efb367f 690 Gene3D G3DSA:2.60.40.1180 452 556 3.0E-4 T 28-03-2018 SmaCSM2_RS14805 d01f8babde4f30a75bd3e5f73efb367f 690 Gene3D G3DSA:2.60.40.1180 569 676 0.0036 T 28-03-2018 SmaCSM2_RS14805 d01f8babde4f30a75bd3e5f73efb367f 690 SUPERFAMILY SSF81901 599 639 1.74E-11 T 28-03-2018 SmaCSM2_RS14805 d01f8babde4f30a75bd3e5f73efb367f 690 SUPERFAMILY SSF81901 427 552 1.74E-11 T 28-03-2018 SmaCSM2_RS14805 d01f8babde4f30a75bd3e5f73efb367f 690 Pfam PF13226 Domain of unknown function (DUF4034) 17 280 4.8E-86 T 28-03-2018 IPR025115 Domain of unknown function DUF4034 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 SUPERFAMILY SSF82829 242 325 2.75E-15 T 28-03-2018 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 SUPERFAMILY SSF52402 27 237 5.03E-57 T 28-03-2018 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 11 313 20.868 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 Pfam PF09179 TilS substrate binding domain 254 321 1.3E-9 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 SUPERFAMILY SSF56037 331 439 8.89E-21 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 28 209 2.1E-46 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 Pfam PF01171 PP-loop family 28 204 4.5E-50 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 Pfam PF11734 TilS substrate C-terminal domain 364 437 6.6E-17 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 SMART SM00977 364 437 6.6E-15 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 Gene3D G3DSA:3.40.50.620 22 233 1.4E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15530 167575d3ed77d5987cceda1fc2067fc9 442 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 364 409 3.7E-11 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 Gene3D G3DSA:1.10.8.350 97 199 2.6E-33 T 28-03-2018 SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 Pfam PF13406 Transglycosylase SLT domain 31 326 6.4E-107 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 Gene3D G3DSA:1.10.530.10 205 333 2.6E-34 T 28-03-2018 SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 SUPERFAMILY SSF47090 334 408 5.23E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 SUPERFAMILY SSF53955 19 330 2.81E-96 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 30 329 2.2E-110 T 28-03-2018 IPR011970 Lytic murein transglycosylase SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 Pfam PF01471 Putative peptidoglycan binding domain 348 403 5.5E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS21535 8194f98bdeecd62701421114d7b36a51 415 Gene3D G3DSA:1.10.101.10 334 409 4.7E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 3.5E-21 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 167 195 3.5E-21 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 68 80 3.5E-21 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 3.5E-21 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 Gene3D G3DSA:3.30.70.1120 101 170 0.024 T 28-03-2018 SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 167 195 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 Pfam PF00482 Type II secretion system (T2SS), protein F 276 397 1.9E-27 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS02965 4faff088a749154f2281a7613e66527d 406 Pfam PF00482 Type II secretion system (T2SS), protein F 72 195 9.3E-31 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS09585 b34f10250ff8d62277c039003644ce90 340 SUPERFAMILY SSF53067 22 333 9.47E-47 T 28-03-2018 SmaCSM2_RS09585 b34f10250ff8d62277c039003644ce90 340 Gene3D G3DSA:3.40.367.20 128 318 3.7E-25 T 28-03-2018 SmaCSM2_RS09585 b34f10250ff8d62277c039003644ce90 340 Pfam PF02685 Glucokinase 24 333 2.7E-83 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SmaCSM2_RS09585 b34f10250ff8d62277c039003644ce90 340 Gene3D G3DSA:3.30.420.40 10 127 7.2E-14 T 28-03-2018 SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Pfam PF00571 CBS domain 278 327 3.2E-7 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Pfam PF00571 CBS domain 212 265 0.0034 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 SMART SM00116 279 327 0.016 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 SMART SM00116 218 267 52.0 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Pfam PF01595 Domain of unknown function DUF21 3 194 7.5E-47 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 SMART SM01091 343 425 7.0E-29 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Gene3D G3DSA:3.20.20.70 116 350 1.6E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 SUPERFAMILY SSF54631 196 328 3.42E-27 T 28-03-2018 SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Pfam PF03471 Transporter associated domain 345 423 3.4E-20 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 SUPERFAMILY SSF56176 338 423 8.72E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS07975 6c6a1af790c172a86ab4248cc1c80be7 434 Gene3D G3DSA:3.30.465.10 351 434 9.1E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 1.8E-172 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Gene3D G3DSA:3.90.600.10 330 424 7.4E-31 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Gene3D G3DSA:3.40.50.20 2 95 7.1E-39 T 28-03-2018 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 SMART SM01209 103 296 1.3E-137 T 28-03-2018 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Gene3D G3DSA:3.30.1490.20 134 189 5.9E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Gene3D G3DSA:3.30.470.20 191 329 3.2E-61 T 28-03-2018 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 SMART SM01210 330 423 1.4E-45 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 421 7.5E-25 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 SUPERFAMILY SSF51246 330 424 4.71E-27 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 2.9E-80 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.3E-35 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 42.402 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 SUPERFAMILY SSF56059 104 323 2.3E-65 T 28-03-2018 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS19405 28d47bc325e2409915bf0a61684761b5 427 SUPERFAMILY SSF52440 1 103 1.44E-36 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 6.5E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 6.5E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 6.5E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 SUPERFAMILY SSF54909 67 156 3.22E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 Gene3D G3DSA:3.30.70.920 60 151 6.9E-28 T 28-03-2018 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 3.2E-19 T 28-03-2018 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 SUPERFAMILY SSF46785 6 95 5.97E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 Gene3D G3DSA:1.10.10.10 1 58 3.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 SMART SM00344 7 116 5.1E-34 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SmaCSM2_RS00255 4f76a679d8b9837e62f5671288e0cdc7 161 Pfam PF01037 Lrp/AsnC ligand binding domain 73 147 2.6E-22 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 Pfam PF03466 LysR substrate binding domain 94 291 1.5E-27 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 Gene3D G3DSA:1.10.10.10 3 93 8.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 5.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 SUPERFAMILY SSF46785 7 115 4.68E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 Gene3D G3DSA:3.40.190.10 95 179 6.6E-17 T 28-03-2018 SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 SUPERFAMILY SSF53850 95 295 2.53E-29 T 28-03-2018 SmaCSM2_RS11510 7662829ce0e80123ebca42479159bf3b 308 Gene3D G3DSA:3.40.190.10 180 262 2.4E-10 T 28-03-2018 SmaCSM2_RS07230 d39f6eb5ce7fd1d3a20971d8564a58cc 385 Pfam PF16074 Type IV Pilus-assembly protein W 241 380 4.7E-23 T 28-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 SmaCSM2_RS07230 d39f6eb5ce7fd1d3a20971d8564a58cc 385 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07230 d39f6eb5ce7fd1d3a20971d8564a58cc 385 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 2.0E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07230 d39f6eb5ce7fd1d3a20971d8564a58cc 385 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 1.8E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS19905 4e97f878b3d2c0f6aae7bdd0015f69e1 144 Gene3D G3DSA:3.10.450.40 84 138 0.16 T 28-03-2018 SmaCSM2_RS19905 4e97f878b3d2c0f6aae7bdd0015f69e1 144 Gene3D G3DSA:3.10.450.40 18 80 2.2E-5 T 28-03-2018 SmaCSM2_RS19905 4e97f878b3d2c0f6aae7bdd0015f69e1 144 Pfam PF13670 Peptidase propeptide and YPEB domain 7 76 4.0E-12 T 28-03-2018 IPR025711 PepSY domain SmaCSM2_RS19905 4e97f878b3d2c0f6aae7bdd0015f69e1 144 Pfam PF13670 Peptidase propeptide and YPEB domain 84 137 1.1E-5 T 28-03-2018 IPR025711 PepSY domain SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.551 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 1.9E-96 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 SUPERFAMILY SSF48592 406 521 1.07E-77 T 28-03-2018 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 SUPERFAMILY SSF48592 7 134 1.07E-77 T 28-03-2018 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 Gene3D G3DSA:1.10.560.10 1 184 1.2E-43 T 28-03-2018 IPR027413 GroEL-like equatorial domain SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 Gene3D G3DSA:3.50.7.10 185 373 1.4E-94 T 28-03-2018 IPR027409 GroEL-like apical domain SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 SUPERFAMILY SSF52029 184 376 1.57E-81 T 28-03-2018 IPR027409 GroEL-like apical domain SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 7.1E-253 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 Gene3D G3DSA:1.10.560.10 374 516 3.7E-26 T 28-03-2018 IPR027413 GroEL-like equatorial domain SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 SUPERFAMILY SSF54849 138 203 8.93E-23 T 28-03-2018 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 PRINTS PR00298 60kDa chaperonin signature 398 419 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 PRINTS PR00298 60kDa chaperonin signature 83 110 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 PRINTS PR00298 60kDa chaperonin signature 268 291 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 PRINTS PR00298 60kDa chaperonin signature 27 53 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS19220 b1776daa816c647edd3b21e5b0618171 549 PRINTS PR00298 60kDa chaperonin signature 350 375 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 SUPERFAMILY SSF52540 340 588 2.3E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 Gene3D G3DSA:1.20.1560.10 4 336 4.0E-66 T 28-03-2018 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 16 588 3.4E-269 T 28-03-2018 IPR011918 ABC transporter, ATP-binding/permease protein SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 Gene3D G3DSA:3.40.50.300 347 584 1.9E-79 T 28-03-2018 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 Pfam PF00664 ABC transporter transmembrane region 36 297 2.9E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 Pfam PF00005 ABC transporter 368 517 2.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 SMART SM00382 377 563 4.7E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 SUPERFAMILY SSF90123 21 336 2.35E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS08785 4f032f0abbdbf8636c4b3367ec4f41fb 590 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 357 3.2E-111 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 105 1.5E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 Gene3D G3DSA:3.40.430.10 131 361 4.4E-69 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 Pfam PF01872 RibD C-terminal domain 153 355 1.2E-45 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 Gene3D G3DSA:3.40.140.10 7 130 1.3E-31 T 28-03-2018 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 SUPERFAMILY SSF53597 151 359 5.89E-58 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 SUPERFAMILY SSF53927 9 150 3.01E-45 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 94 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 PIRSF PIRSF006769 5 360 8.7E-120 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SmaCSM2_RS03115 ef5fa3fe8e2c29295d012b97d29e153a 361 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 152 359 1.7E-50 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 SmaCSM2_RS16820 5d6b34a0d29b8bf8c08f5178484de56a 236 Gene3D G3DSA:3.40.30.10 1 100 3.7E-12 T 28-03-2018 SmaCSM2_RS16820 5d6b34a0d29b8bf8c08f5178484de56a 236 SUPERFAMILY SSF47616 103 233 3.84E-18 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS16820 5d6b34a0d29b8bf8c08f5178484de56a 236 Pfam PF14497 Glutathione S-transferase, C-terminal domain 109 214 6.9E-25 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS16820 5d6b34a0d29b8bf8c08f5178484de56a 236 Gene3D G3DSA:1.20.1050.10 101 212 2.0E-16 T 28-03-2018 SmaCSM2_RS16820 5d6b34a0d29b8bf8c08f5178484de56a 236 SUPERFAMILY SSF52833 1 82 2.58E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 Gene3D G3DSA:2.60.120.200 126 345 9.0E-24 T 28-03-2018 SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 Pfam PF10102 Domain of unknown function (DUF2341) 76 155 4.9E-19 T 28-03-2018 IPR018765 Domain of unknown function DUF2341 SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 SMART SM00560 204 330 4.6E-4 T 28-03-2018 IPR006558 LamG-like jellyroll fold SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 SUPERFAMILY SSF49899 139 330 1.09E-20 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 Pfam PF01618 MotA/TolQ/ExbB proton channel family 451 568 1.7E-27 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS12100 5e51404e04ae42719e8a241f2f2dbc94 594 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 202 328 2.4E-17 T 28-03-2018 SmaCSM2_RS18430 3a4bcf2f3484598bbdf7f33399113a1e 461 SUPERFAMILY SSF56954 4 458 7.59E-105 T 28-03-2018 SmaCSM2_RS18430 3a4bcf2f3484598bbdf7f33399113a1e 461 Gene3D G3DSA:1.20.1600.10 19 461 4.8E-90 T 28-03-2018 SmaCSM2_RS18430 3a4bcf2f3484598bbdf7f33399113a1e 461 Pfam PF02321 Outer membrane efflux protein 275 454 5.0E-29 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS18430 3a4bcf2f3484598bbdf7f33399113a1e 461 Pfam PF02321 Outer membrane efflux protein 63 245 2.4E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS18430 3a4bcf2f3484598bbdf7f33399113a1e 461 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 456 3.0E-111 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR01032 Gene IV protein signature 625 647 3.6E-14 T 28-03-2018 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR01032 Gene IV protein signature 572 600 3.6E-14 T 28-03-2018 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR01032 Gene IV protein signature 499 522 3.6E-14 T 28-03-2018 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 474 498 9.4E-30 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 609 627 9.4E-30 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 632 646 9.4E-30 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 392 402 9.4E-30 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 509 519 9.4E-30 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 Pfam PF00263 Bacterial type II and III secretion system protein 478 645 7.9E-50 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 38 654 3.9E-188 T 28-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 Pfam PF03958 Bacterial type II/III secretion system short domain 195 261 3.3E-11 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 Pfam PF03958 Bacterial type II/III secretion system short domain 268 392 6.0E-16 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS12165 57fb8fb75897f0e594de7082e4d0d68d 793 Pfam PF03958 Bacterial type II/III secretion system short domain 131 190 1.9E-10 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 Pfam PF12704 MacB-like periplasmic core domain 280 499 7.2E-40 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 Gene3D G3DSA:3.90.180.10 275 508 0.0016 T 28-03-2018 SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 Pfam PF00005 ABC transporter 29 177 5.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 SUPERFAMILY SSF52540 9 232 3.22E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 Pfam PF02687 FtsX-like permease family 561 649 1.2E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 Gene3D G3DSA:3.40.50.300 6 273 3.4E-61 T 28-03-2018 SmaCSM2_RS13525 ba9f6d10895b8c169121f6de84b23247 655 SMART SM00382 38 225 1.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS20410 b16921a54288904d8820b4605c642970 226 Pfam PF02630 SCO1/SenC 41 178 3.0E-30 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20410 b16921a54288904d8820b4605c642970 226 SUPERFAMILY SSF52833 44 199 3.39E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20410 b16921a54288904d8820b4605c642970 226 Gene3D G3DSA:3.40.30.10 36 199 2.6E-26 T 28-03-2018 SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 SUPERFAMILY SSF82171 226 514 5.49E-13 T 28-03-2018 SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 SUPERFAMILY SSF82171 96 169 5.49E-13 T 28-03-2018 SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 Pfam PF00326 Prolyl oligopeptidase family 660 817 4.9E-23 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 SUPERFAMILY SSF53474 563 817 3.57E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 Gene3D G3DSA:3.40.50.1820 523 820 8.9E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 Gene3D G3DSA:2.140.10.30 31 184 6.0E-6 T 28-03-2018 SmaCSM2_RS13790 2f0212745c08f5c21ca51da09f4187dc 820 Gene3D G3DSA:2.140.10.30 185 522 1.3E-5 T 28-03-2018 SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 Gene3D G3DSA:3.40.50.300 7 482 6.8E-18 T 28-03-2018 SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 Pfam PF13307 Helicase C-terminal domain 539 694 1.5E-30 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 SUPERFAMILY SSF52540 49 104 2.53E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 SUPERFAMILY SSF52540 503 676 2.53E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 SUPERFAMILY SSF52540 461 475 2.53E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 SUPERFAMILY SSF52540 207 287 2.53E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 Gene3D G3DSA:3.40.50.300 512 691 2.6E-11 T 28-03-2018 SmaCSM2_RS20790 3262729a39becd5f1c426d2333dc29b6 700 SMART SM00491 551 681 5.3E-27 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 Pfam PF09186 Domain of unknown function (DUF1949) 135 188 2.9E-10 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 SUPERFAMILY SSF54211 5 122 8.34E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 Gene3D G3DSA:3.30.230.30 1 125 2.0E-41 T 28-03-2018 IPR001498 Impact, N-terminal SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 1.6E-28 T 28-03-2018 IPR001498 Impact, N-terminal SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 SUPERFAMILY SSF54980 127 195 6.83E-11 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS08790 b8cac95a3151a43a33df5913419bea87 198 Gene3D G3DSA:3.30.70.240 127 191 7.4E-13 T 28-03-2018 SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 536 4.4E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 533 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 Pfam PF05226 CHASE2 domain 21 313 4.3E-48 T 28-03-2018 IPR007890 CHASE2 SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 SMART SM01080 31 316 5.1E-59 T 28-03-2018 IPR007890 CHASE2 SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 SMART SM00267 364 538 1.2E-55 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 Gene3D G3DSA:3.30.70.270 368 538 3.3E-50 T 28-03-2018 SmaCSM2_RS15655 6634e57d59e88b766f008b051ccb129f 541 SUPERFAMILY SSF55073 380 537 1.49E-43 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS16930 20a5ebf2cd7fcba5b84fc19d6a169d03 154 Gene3D G3DSA:3.30.700.10 14 152 1.0E-27 T 28-03-2018 SmaCSM2_RS16930 20a5ebf2cd7fcba5b84fc19d6a169d03 154 Pfam PF00114 Pilin (bacterial filament) 43 152 7.6E-14 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS16930 20a5ebf2cd7fcba5b84fc19d6a169d03 154 SUPERFAMILY SSF54523 14 152 5.23E-25 T 28-03-2018 SmaCSM2_RS16930 20a5ebf2cd7fcba5b84fc19d6a169d03 154 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 33 3.3E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS16930 20a5ebf2cd7fcba5b84fc19d6a169d03 154 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 2.6E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 Gene3D G3DSA:1.10.238.10 23 82 0.0073 T 28-03-2018 SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 ProSitePatterns PS00018 EF-hand calcium-binding domain. 105 117 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 Gene3D G3DSA:1.10.1330.10 83 127 3.8E-8 T 28-03-2018 SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 Pfam PF13202 EF hand 98 119 5.3E-6 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 Pfam PF13202 EF hand 78 90 0.018 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS01960 f8dc435f4d8b4ab366c03c30cf626336 136 SUPERFAMILY SSF47473 73 121 3.17E-9 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 Gene3D G3DSA:3.40.470.10 8 171 2.9E-42 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 SMART SM00986 11 167 5.4E-6 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 SUPERFAMILY SSF52141 11 167 2.22E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 10 162 2.2E-37 T 28-03-2018 IPR026353 Hypoxanthine-DNA glycosylase SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 Pfam PF03167 Uracil DNA glycosylase superfamily 14 163 7.2E-11 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS18745 6bb0585b24ae0efe71c907613cb2208a 171 SMART SM00987 11 167 5.4E-6 T 28-03-2018 SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 1.4E-48 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 144 243 5.6E-33 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 SUPERFAMILY SSF117143 93 222 7.59E-36 T 28-03-2018 SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 Pfam PF00460 Flagella basal body rod protein 5 35 2.5E-12 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 259 1.1E-25 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain SmaCSM2_RS10275 872695335003fee125c7466db9a20052 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 1.1E-114 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 501 6.5E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.50.50.60 196 227 1.8E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.50.50.60 228 339 3.6E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 344 364 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 SUPERFAMILY SSF52833 1 101 6.71E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.50.50.60 340 442 3.0E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 SUPERFAMILY SSF52833 105 196 1.12E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 516 2.3E-241 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.40.30.10 1 94 2.3E-25 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 SUPERFAMILY SSF51905 206 513 2.3E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.40.30.10 103 195 4.2E-10 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 404 420 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 443 464 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 352 376 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 477 495 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 337 349 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 315 323 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 3.7E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Pfam PF13192 Thioredoxin domain 125 195 6.1E-9 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 Gene3D G3DSA:3.50.50.60 443 529 2.3E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PIRSF PIRSF000238 1 520 7.6E-266 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 332 7.6E-40 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 489 7.6E-40 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 457 7.6E-40 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 374 7.6E-40 T 28-03-2018 SmaCSM2_RS03655 7c7086a149de28676ffa5d391d53c8f5 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 7.6E-40 T 28-03-2018 SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 SUPERFAMILY SSF53383 4 373 5.64E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 Pfam PF00266 Aminotransferase class-V 4 365 2.5E-71 T 28-03-2018 IPR000192 Aminotransferase class V domain SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 PIRSF PIRSF005572 1 378 3.6E-108 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 Gene3D G3DSA:3.90.1150.10 252 365 4.8E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS11070 e73e2f32c072224d02ebdf7ac016ab54 378 Gene3D G3DSA:3.40.640.10 12 251 1.7E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS06170 9ceef3afe105c14c7f04a79f383a627e 375 Pfam PF12698 ABC-2 family transporter protein 25 361 5.8E-30 T 28-03-2018 SmaCSM2_RS06170 9ceef3afe105c14c7f04a79f383a627e 375 Gene3D G3DSA:3.40.1710.10 42 193 2.9E-20 T 28-03-2018 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 SUPERFAMILY SSF53706 1 653 1.44E-231 T 28-03-2018 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 SUPERFAMILY SSF50692 632 662 1.89E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 SUPERFAMILY SSF50692 692 821 1.89E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Pfam PF01568 Molydopterin dinucleotide binding domain 699 812 5.8E-14 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Pfam PF00384 Molybdopterin oxidoreductase 12 389 2.3E-23 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Gene3D G3DSA:2.40.40.20 643 821 3.3E-34 T 28-03-2018 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Gene3D G3DSA:3.40.50.740 283 462 1.7E-29 T 28-03-2018 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 820 0.0 T 28-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Gene3D G3DSA:3.40.228.10 1 282 5.8E-75 T 28-03-2018 SmaCSM2_RS17390 df307e6e10933bb4e5abf31c6ec4bcac 821 Gene3D G3DSA:3.40.228.10 561 642 1.0E-10 T 28-03-2018 SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 PRINTS PR01021 OMPA domain signature 69 91 3.0E-14 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 PRINTS PR01021 OMPA domain signature 114 130 3.0E-14 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 PRINTS PR01021 OMPA domain signature 99 114 3.0E-14 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 Pfam PF00691 OmpA family 68 163 4.3E-18 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 67 169 7.7E-42 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 SUPERFAMILY SSF103088 65 169 2.49E-33 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS16670 f5dedbf2739c902ba142eb9763832681 172 Gene3D G3DSA:3.30.1330.60 22 172 9.0E-34 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 Pfam PF13202 EF hand 69 86 7.6E-5 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 Pfam PF13202 EF hand 43 61 2.6E-5 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 ProSitePatterns PS00018 EF-hand calcium-binding domain. 48 60 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 Gene3D G3DSA:1.10.238.10 52 72 9.3E-6 T 28-03-2018 SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 SUPERFAMILY SSF47473 43 87 3.01E-10 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 ProSitePatterns PS00018 EF-hand calcium-binding domain. 73 85 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 Gene3D G3DSA:1.10.1330.10 73 89 0.015 T 28-03-2018 SmaCSM2_RS10840 0196cf1768da5f056f60332ad9feeabf 91 Gene3D G3DSA:1.10.1330.10 8 51 0.0015 T 28-03-2018 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 53 65 3.1E-29 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 248 263 3.1E-29 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 396 415 3.1E-29 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 3.1E-29 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 320 336 3.1E-29 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 Pfam PF05746 DALR anticodon binding domain 583 678 6.4E-7 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 551 7.1E-192 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 6 689 8.0E-207 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 Gene3D G3DSA:1.10.730.10 577 685 3.2E-14 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 SMART SM00836 586 689 0.0047 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 689 24.573 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21430 99a34eb26b59862d23343b3459619b2b 691 SUPERFAMILY SSF109604 352 489 5.02E-13 T 28-03-2018 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 PIRSF PIRSF015626 6 279 2.3E-79 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 11 275 32.871 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 Pfam PF02634 FdhD/NarQ family 35 274 3.1E-75 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 32 275 7.0E-65 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 Gene3D G3DSA:3.10.20.10 37 93 2.2E-19 T 28-03-2018 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 Gene3D G3DSA:3.40.140.10 139 279 1.1E-48 T 28-03-2018 SmaCSM2_RS11845 fd76b0c810cfaa7c463ee95a29a766eb 282 SUPERFAMILY SSF53927 16 274 2.59E-78 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS17835 3689585f4756b179734f972332dae75f 149 Pfam PF01797 Transposase IS200 like 18 124 7.6E-13 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS17835 3689585f4756b179734f972332dae75f 149 Gene3D G3DSA:3.30.70.1290 4 134 1.1E-30 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS17835 3689585f4756b179734f972332dae75f 149 SUPERFAMILY SSF143422 6 133 4.58E-30 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS17835 3689585f4756b179734f972332dae75f 149 SMART SM01321 13 127 8.7E-32 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:3.30.2090.10 720 815 5.3E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 451 474 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 476 499 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 2.4E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1041 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Pfam PF00873 AcrB/AcrD/AcrF family 5 1034 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82866 811 1035 4.19E-54 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:1.20.1640.10 291 516 8.9E-36 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:3.30.70.1430 564 669 1.8E-14 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:3.30.70.1430 42 143 1.7E-23 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82693 564 664 6.28E-7 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82693 273 329 5.41E-17 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82693 152 187 5.41E-17 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82866 295 501 4.05E-34 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:3.30.2090.10 187 273 5.3E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82714 721 813 3.14E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82693 42 127 9.94E-23 T 28-03-2018 SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 SUPERFAMILY SSF82714 188 271 9.55E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS00150 60e929b2f1cb2ee495a500c44082e301 1045 Gene3D G3DSA:1.20.1640.10 816 1036 2.9E-35 T 28-03-2018 SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 PIRSF PIRSF002849 4 341 2.4E-123 T 28-03-2018 SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 56 186 4.4E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 Gene3D G3DSA:3.40.50.300 37 203 3.4E-29 T 28-03-2018 SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 Gene3D G3DSA:1.10.8.300 223 338 1.1E-31 T 28-03-2018 SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 SUPERFAMILY SSF52540 26 313 6.6E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17265 d4c51d2e60ba9a2532dcf23d160bface 341 SMART SM00382 53 194 1.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 Gene3D G3DSA:1.10.10.10 121 223 3.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 SMART SM00448 1 112 3.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 4.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 SUPERFAMILY SSF52172 1 118 3.13E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 SUPERFAMILY SSF46894 118 220 4.54E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 SMART SM00862 144 219 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11960 1e7b6bb6611015ff21fd68d38b6df5fa 224 Gene3D G3DSA:3.40.50.2300 1 120 1.8E-30 T 28-03-2018 SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 Gene3D G3DSA:3.40.50.300 4 205 1.7E-38 T 28-03-2018 SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 7 203 4.0E-68 T 28-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 SUPERFAMILY SSF52540 6 205 1.11E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 Pfam PF00005 ABC transporter 25 160 3.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS14470 7ab27871184fc2097384395da57a9669 209 SMART SM00382 31 209 4.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04875 702d67aec1424adfb1b9cdf75143ea57 377 Gene3D G3DSA:1.20.1250.20 14 190 9.2E-17 T 28-03-2018 SmaCSM2_RS04875 702d67aec1424adfb1b9cdf75143ea57 377 Pfam PF07690 Major Facilitator Superfamily 211 371 1.3E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS04875 702d67aec1424adfb1b9cdf75143ea57 377 Pfam PF07690 Major Facilitator Superfamily 17 178 3.5E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS04875 702d67aec1424adfb1b9cdf75143ea57 377 Gene3D G3DSA:1.20.1250.20 191 376 6.4E-16 T 28-03-2018 SmaCSM2_RS04875 702d67aec1424adfb1b9cdf75143ea57 377 SUPERFAMILY SSF103473 16 376 2.88E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 Gene3D G3DSA:1.10.287.130 141 250 3.0E-11 T 28-03-2018 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 Gene3D G3DSA:3.30.565.10 254 404 7.3E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 403 3.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 Gene3D G3DSA:3.30.450.20 16 135 8.3E-9 T 28-03-2018 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 SUPERFAMILY SSF47384 148 188 1.0E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 382 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 401 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 250 5.3E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 SMART SM00387 296 404 5.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10325 e86005906d1def3d5bca8d7a97b4f888 406 SUPERFAMILY SSF55874 251 402 7.6E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 SUPERFAMILY SSF52540 160 405 1.97E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 8 629 37.611 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 607 6.6E-242 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Gene3D G3DSA:1.10.8.60 346 428 1.6E-25 T 28-03-2018 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Pfam PF01434 Peptidase family M41 396 606 1.3E-82 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 SMART SM00382 198 337 1.6E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Pfam PF06480 FtsH Extracellular 10 104 1.8E-11 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Gene3D G3DSA:3.40.50.300 142 345 1.1E-63 T 28-03-2018 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 SUPERFAMILY SSF140990 417 617 1.09E-76 T 28-03-2018 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 3.9E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS08100 ac41e6c04aee7122ba2f3416465afb77 646 ProSitePatterns PS00674 AAA-protein family signature. 305 323 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Gene3D G3DSA:3.30.450.20 323 452 1.1E-14 T 28-03-2018 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SUPERFAMILY SSF47384 434 514 2.35E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 560 673 1.3E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SMART SM00448 803 914 1.1E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Pfam PF00512 His Kinase A (phospho-acceptor) domain 448 513 1.4E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Gene3D G3DSA:3.40.50.2300 797 921 5.2E-40 T 28-03-2018 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 671 3.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 3.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 3.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 652 3.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SUPERFAMILY SSF55874 503 673 5.37E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Gene3D G3DSA:1.10.287.130 453 507 1.2E-17 T 28-03-2018 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Gene3D G3DSA:3.30.565.10 508 674 1.8E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SUPERFAMILY SSF52172 802 918 2.28E-38 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 Pfam PF00072 Response regulator receiver domain 805 915 1.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SMART SM00387 560 674 1.1E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03875 878e82dc42d65ee13ac0d9f654b6ad95 923 SMART SM00388 448 513 7.1E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 SUPERFAMILY SSF55681 103 463 7.17E-96 T 28-03-2018 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 Pfam PF01336 OB-fold nucleic acid binding domain 20 97 4.3E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 457 2.5E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 SUPERFAMILY SSF50249 17 100 2.79E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 464 45.239 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 Gene3D G3DSA:2.40.50.140 7 105 7.0E-18 T 28-03-2018 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 Gene3D G3DSA:3.30.930.10 126 460 3.0E-91 T 28-03-2018 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 218 9.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 379 395 9.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 222 235 9.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 419 433 9.2E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13915 aa20e5cc668d3260c82126193491ffac 464 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 15 464 7.8E-191 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 SmaCSM2_RS02385 b0a9baf5cfe7b1d53da39dd2b5ac8851 91 Gene3D G3DSA:1.10.720.10 20 46 0.023 T 28-03-2018 SmaCSM2_RS02385 b0a9baf5cfe7b1d53da39dd2b5ac8851 91 Pfam PF13223 Protein of unknown function (DUF4031) 3 79 1.7E-31 T 28-03-2018 IPR025109 Domain of unknown function DUF4031 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 9.0E-38 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 SUPERFAMILY SSF55347 132 274 2.91E-59 T 28-03-2018 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 PIRSF PIRSF006205 7 396 1.7E-148 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Gene3D G3DSA:3.40.50.720 7 156 4.7E-46 T 28-03-2018 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 391 3.0E-136 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Gene3D G3DSA:1.10.1740.10 313 394 7.3E-29 T 28-03-2018 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 10 138 1.8E-41 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 152 239 3.9E-39 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 SUPERFAMILY SSF51735 8 156 3.31E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 10 392 45.606 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS06615 936bf00115c4cafd1adfe74f3a3aade2 396 SUPERFAMILY SSF69055 303 393 5.36E-30 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SmaCSM2_RS07600 c5fd3e9c17918f16be2903f4925df71a 119 Pfam PF11190 Protein of unknown function (DUF2976) 32 118 1.5E-32 T 28-03-2018 IPR021356 Integrating conjugative element protein PFL4702 SmaCSM2_RS07600 c5fd3e9c17918f16be2903f4925df71a 119 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 16 119 9.6E-45 T 28-03-2018 IPR021356 Integrating conjugative element protein PFL4702 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 Pfam PF00258 Flavodoxin 83 209 8.0E-23 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 Gene3D G3DSA:3.40.50.80 389 533 3.6E-22 T 28-03-2018 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 Pfam PF00175 Oxidoreductase NAD-binding domain 403 507 1.2E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 493 501 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 402 421 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 439 450 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 338 345 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 426 435 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 366 375 3.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 Gene3D G3DSA:3.40.50.360 65 222 3.9E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00369 Flavodoxin signature 184 203 2.0E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00369 Flavodoxin signature 160 170 2.0E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00369 Flavodoxin signature 81 94 2.0E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 PRINTS PR00369 Flavodoxin signature 129 140 2.0E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 Gene3D G3DSA:2.40.30.10 223 386 4.0E-13 T 28-03-2018 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 SUPERFAMILY SSF63380 227 393 7.01E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 SUPERFAMILY SSF52218 78 218 1.72E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS05235 86541009476b23896f14f543338849da 534 SUPERFAMILY SSF52343 397 534 7.2E-32 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82866 795 1016 3.27E-49 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:3.30.2090.10 180 266 2.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82866 291 490 2.22E-44 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82693 40 133 3.49E-24 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:1.20.1640.10 267 491 5.6E-41 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:3.30.70.1320 755 832 3.3E-7 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82693 136 181 4.6E-21 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82693 268 324 4.6E-21 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:3.30.70.1430 558 657 3.1E-10 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82714 182 264 2.22E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Pfam PF00873 AcrB/AcrD/AcrF family 4 1012 2.8E-294 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:3.30.70.1430 40 141 1.2E-26 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82693 556 654 2.35E-13 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:3.30.70.1440 660 754 1.9E-14 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 5.2E-75 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 Gene3D G3DSA:1.20.1640.10 833 1027 2.4E-41 T 28-03-2018 SmaCSM2_RS17100 7e19e0b3159bae28e80bd6e596ef02b3 1041 SUPERFAMILY SSF82714 709 793 1.44E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 Gene3D G3DSA:3.40.50.300 219 649 3.0E-54 T 28-03-2018 SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 Pfam PF01580 FtsK/SpoIIIE family 396 609 6.3E-65 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 SMART SM00382 431 630 7.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 SMART SM00843 719 784 3.8E-39 T 28-03-2018 IPR018541 FtsK gamma domain SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 SUPERFAMILY SSF52540 368 681 2.66E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 Pfam PF09397 Ftsk gamma domain 721 781 1.7E-26 T 28-03-2018 IPR018541 FtsK gamma domain SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 Gene3D G3DSA:1.10.10.10 721 775 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 32 206 1.4E-40 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region SmaCSM2_RS10445 eebc327818fac8867465aefb4f1f4a40 786 SUPERFAMILY SSF46785 719 784 1.68E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00520 f58560b3b21b2e27dc2f9c6c1bfea6cc 444 Gene3D G3DSA:3.30.2290.10 3 212 3.6E-29 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SmaCSM2_RS00520 f58560b3b21b2e27dc2f9c6c1bfea6cc 444 Pfam PF01523 Putative modulator of DNA gyrase 25 310 1.8E-52 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS00520 f58560b3b21b2e27dc2f9c6c1bfea6cc 444 SUPERFAMILY SSF111283 7 438 1.57E-90 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 34 470 2.2E-184 T 28-03-2018 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 34 467 2.4E-146 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 SMART SM00729 177 397 4.8E-61 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 Gene3D G3DSA:3.80.30.20 174 411 3.1E-51 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 Pfam PF01938 TRAM domain 409 470 2.7E-17 T 28-03-2018 IPR002792 TRAM domain SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 181 201 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 Pfam PF00919 Uncharacterized protein family UPF0004 34 134 2.9E-28 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 33 470 72.309 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 SUPERFAMILY SSF102114 154 402 1.29E-61 T 28-03-2018 SmaCSM2_RS07115 d907f089200e714511a342cb796e94fb 472 Pfam PF04055 Radical SAM superfamily 181 355 2.7E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS21690 485ad5a8fbb08c1240905db32be054e7 209 Pfam PF01810 LysE type translocator 18 208 9.6E-38 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS21690 485ad5a8fbb08c1240905db32be054e7 209 PIRSF PIRSF006324 3 209 2.5E-52 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS16745 bb6f1c40ab3688bb8086146db96c4dab 248 Pfam PF11218 Protein of unknown function (DUF3011) 34 245 8.9E-71 T 28-03-2018 IPR021381 Protein of unknown function DUF3011 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:3.90.1170.30 64 100 0.029 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:1.10.287.990 163 231 6.3E-21 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:3.30.390.30 490 597 2.7E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 166 176 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 SUPERFAMILY SSF51905 132 511 2.3E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 423 445 6.7E-39 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 410 6.7E-39 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 320 6.7E-39 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 152 6.7E-39 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 281 6.7E-39 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 SUPERFAMILY SSF55424 475 597 1.48E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 477 583 3.7E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 133 458 2.9E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 473 494 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 327 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 154 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 180 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 445 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 538 553 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 560 580 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 275 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 409 2.5E-69 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Pfam PF00364 Biotin-requiring enzyme 5 76 4.2E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:3.50.50.60 385 489 3.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 131 587 6.5E-152 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 PIRSF PIRSF000350 58 598 1.2E-86 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:2.40.50.100 4 63 2.0E-13 T 28-03-2018 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 Gene3D G3DSA:3.50.50.60 243 377 4.3E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18735 74de1a96164d933856d27a7fa54c5752 602 SUPERFAMILY SSF51230 2 96 1.96E-23 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS18850 b253649661761f20f37f4e99a7460274 303 Gene3D G3DSA:3.30.750.44 19 90 1.9E-6 T 28-03-2018 SmaCSM2_RS18850 b253649661761f20f37f4e99a7460274 303 Gene3D G3DSA:3.90.226.10 99 295 2.0E-34 T 28-03-2018 SmaCSM2_RS18850 b253649661761f20f37f4e99a7460274 303 SMART SM00245 68 285 1.7E-13 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS18850 b253649661761f20f37f4e99a7460274 303 SUPERFAMILY SSF52096 25 284 2.15E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS18850 b253649661761f20f37f4e99a7460274 303 Pfam PF03572 Peptidase family S41 118 282 1.6E-27 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 Gene3D G3DSA:3.90.650.10 176 351 2.8E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 SUPERFAMILY SSF56042 176 349 2.09E-58 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 Gene3D G3DSA:3.30.1330.10 42 166 1.1E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 Pfam PF00586 AIR synthase related protein, N-terminal domain 68 152 1.9E-14 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 351 46.862 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 341 3.1E-138 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 SUPERFAMILY SSF55326 12 172 8.52E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS05175 1c3032764a80a542266f681bd4df1e85 352 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 345 1.3E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 6 439 61.211 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 Pfam PF04055 Radical SAM superfamily 143 320 1.7E-31 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 7 437 4.3E-106 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 SMART SM00729 137 362 5.5E-54 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 Pfam PF00919 Uncharacterized protein family UPF0004 7 98 9.0E-21 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 437 5.7E-175 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 Gene3D G3DSA:2.40.50.140 377 442 6.4E-19 T 28-03-2018 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 Gene3D G3DSA:3.80.30.20 134 376 5.5E-49 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SmaCSM2_RS15355 0655bedd233ec0bc96d25b03bc64505a 453 SUPERFAMILY SSF102114 117 368 1.31E-53 T 28-03-2018 SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 Pfam PF00899 ThiF family 119 354 2.8E-66 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 SMART SM00450 6 102 2.4E-14 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 Gene3D G3DSA:3.40.50.720 110 361 6.2E-72 T 28-03-2018 SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 Pfam PF00581 Rhodanese-like domain 8 98 5.8E-9 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 Gene3D G3DSA:3.40.250.10 3 109 5.2E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 SUPERFAMILY SSF52821 2 105 1.7E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS09075 bb05c03614a32ec59b173d625c67f75e 378 SUPERFAMILY SSF69572 116 362 1.83E-90 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SmaCSM2_RS13725 cbbd96808259e1ffaaa036c81cc3b7e0 702 SUPERFAMILY SSF56935 25 701 2.97E-83 T 28-03-2018 SmaCSM2_RS13725 cbbd96808259e1ffaaa036c81cc3b7e0 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 161 5.3E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13725 cbbd96808259e1ffaaa036c81cc3b7e0 702 Gene3D G3DSA:2.170.130.10 25 170 2.8E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13725 cbbd96808259e1ffaaa036c81cc3b7e0 702 Gene3D G3DSA:2.40.170.20 171 701 6.6E-48 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13725 cbbd96808259e1ffaaa036c81cc3b7e0 702 Pfam PF00593 TonB dependent receptor 280 700 1.3E-26 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Gene3D G3DSA:1.20.5.550 29 77 1.2E-17 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Gene3D G3DSA:3.40.309.10 846 1033 4.9E-48 T 28-03-2018 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Gene3D G3DSA:3.20.20.220 123 539 5.6E-103 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Gene3D G3DSA:3.40.605.10 587 845 8.9E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 SUPERFAMILY SSF51730 201 548 6.67E-113 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 SUPERFAMILY SSF53720 590 1057 1.57E-129 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 PIRSF PIRSF000197 18 1069 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Pfam PF01619 Proline dehydrogenase 212 507 7.5E-93 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 85 198 7.2E-45 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 Pfam PF00171 Aldehyde dehydrogenase family 594 1054 9.2E-121 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 854 865 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 550 1050 3.1E-216 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 SmaCSM2_RS01770 d8a6504705d5ab9928567b1bf9992219 1072 SUPERFAMILY SSF81935 28 200 3.92E-63 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 SmaCSM2_RS07410 afb7b1e991f88c1b84d46fb911ad653a 217 Pfam PF03466 LysR substrate binding domain 10 194 1.6E-24 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS07410 afb7b1e991f88c1b84d46fb911ad653a 217 SUPERFAMILY SSF53850 10 194 4.47E-26 T 28-03-2018 SmaCSM2_RS07410 afb7b1e991f88c1b84d46fb911ad653a 217 Gene3D G3DSA:3.40.190.10 94 178 1.6E-11 T 28-03-2018 SmaCSM2_RS07410 afb7b1e991f88c1b84d46fb911ad653a 217 Gene3D G3DSA:3.40.190.10 8 93 8.4E-15 T 28-03-2018 SmaCSM2_RS06265 fdf6d506af5cbdd0c0eb30ae3d39a249 375 Gene3D G3DSA:3.60.21.10 33 362 3.9E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS06265 fdf6d506af5cbdd0c0eb30ae3d39a249 375 SUPERFAMILY SSF56300 96 365 4.75E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS06265 fdf6d506af5cbdd0c0eb30ae3d39a249 375 Pfam PF00149 Calcineurin-like phosphoesterase 102 318 5.8E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SMART SM00533 285 592 1.0E-94 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SUPERFAMILY SSF55271 5 117 1.44E-41 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 9 855 24.876 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Pfam PF05192 MutS domain III 271 560 7.2E-38 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Pfam PF00488 MutS domain V 611 803 1.4E-81 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Pfam PF01624 MutS domain I 10 121 8.2E-41 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Gene3D G3DSA:3.40.50.300 568 805 1.8E-41 T 28-03-2018 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SUPERFAMILY SSF48334 269 566 6.54E-85 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SUPERFAMILY SSF52540 568 804 3.77E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Gene3D G3DSA:3.40.1170.10 1 133 6.9E-45 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 689 705 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Gene3D G3DSA:1.10.1420.10 409 536 2.1E-28 T 28-03-2018 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 9 860 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Gene3D G3DSA:3.30.420.110 134 263 6.5E-30 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SMART SM00534 608 800 3.4E-110 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 SUPERFAMILY SSF53150 116 268 5.1E-41 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Gene3D G3DSA:1.10.1420.10 265 408 1.6E-32 T 28-03-2018 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 PIRSF PIRSF037677 1 191 2.4E-26 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 PIRSF PIRSF037677 213 843 5.4E-119 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Pfam PF05190 MutS family domain IV 429 519 2.6E-29 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS06125 ba7721933b1f9f0d3dc182e3d1ccfa53 863 Pfam PF05188 MutS domain II 131 254 1.1E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS19650 85885b4ead63035f9a77f222202603d8 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.647 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid SmaCSM2_RS19650 85885b4ead63035f9a77f222202603d8 130 Gene3D G3DSA:3.30.230.10 3 130 2.1E-52 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS19650 85885b4ead63035f9a77f222202603d8 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 4.8E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19650 85885b4ead63035f9a77f222202603d8 130 SUPERFAMILY SSF54211 6 130 1.59E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS19650 85885b4ead63035f9a77f222202603d8 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 125 1.0E-63 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 147 6.1E-29 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 148 41.807 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 Pfam PF02381 MraZ protein, putative antitoxin-like 2 75 4.3E-8 T 28-03-2018 IPR020603 MraZ domain SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 Pfam PF02381 MraZ protein, putative antitoxin-like 80 133 2.2E-12 T 28-03-2018 IPR020603 MraZ domain SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 SUPERFAMILY SSF89447 2 136 3.56E-36 T 28-03-2018 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 Gene3D G3DSA:2.10.260.10 81 132 1.1E-7 T 28-03-2018 SmaCSM2_RS03220 c346d814a088c2266f3e1b689a5972f4 148 Gene3D G3DSA:2.10.260.10 3 40 0.062 T 28-03-2018 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 Gene3D G3DSA:3.90.1310.10 34 244 5.7E-52 T 28-03-2018 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 Pfam PF00905 Penicillin binding protein transpeptidase domain 266 603 1.0E-67 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 SUPERFAMILY SSF56601 249 607 1.19E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 SUPERFAMILY SSF56519 57 248 4.05E-50 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 19 607 1.9E-211 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 233 1.0E-43 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SmaCSM2_RS18365 43e187807ec20cfb508ff0d86ff66d40 691 Gene3D G3DSA:3.40.710.10 245 612 9.2E-86 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04565 RNA polymerase Rpb2, domain 3 541 608 1.5E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:3.90.1800.10 1309 1352 5.5E-12 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:2.40.50.150 858 1085 1.0E-50 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1381 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:2.40.50.100 742 824 5.7E-26 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:2.40.270.10 1086 1284 4.1E-78 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:3.90.1100.10 673 741 4.6E-14 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:3.90.1100.10 20 249 1.1E-49 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Gene3D G3DSA:3.90.1100.10 428 672 1.7E-78 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04563 RNA polymerase beta subunit 28 527 1.3E-39 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF00562 RNA polymerase Rpb2, domain 6 746 1306 1.6E-157 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04561 RNA polymerase Rpb2, domain 2 450 482 3.8E-5 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04561 RNA polymerase Rpb2, domain 2 157 227 9.3E-8 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04561 RNA polymerase Rpb2, domain 2 362 420 4.2E-5 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 SUPERFAMILY SSF64484 1080 1382 0.0 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 SUPERFAMILY SSF64484 13 231 0.0 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 SUPERFAMILY SSF64484 349 968 0.0 T 28-03-2018 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF04560 RNA polymerase Rpb2, domain 7 1308 1382 6.8E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 14 1384 12.271 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1104 1116 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03955 ae2dc91491700eeb7189c09c0c95e520 1384 Pfam PF10385 RNA polymerase beta subunit external 1 domain 619 684 2.3E-20 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 6.2E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 SMART SM00862 145 220 2.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 SUPERFAMILY SSF52172 1 123 2.56E-33 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 SUPERFAMILY SSF46894 120 221 1.36E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 SMART SM00448 1 112 3.1E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 Gene3D G3DSA:1.10.10.10 119 224 6.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13505 1e7542852651fe3c3ecae542a4f11161 224 Gene3D G3DSA:3.40.50.2300 1 118 1.9E-29 T 28-03-2018 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 SUPERFAMILY SSF52922 700 888 5.34E-56 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 Gene3D G3DSA:3.40.50.920 705 890 1.1E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 219 292 2.4E-6 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 Gene3D G3DSA:3.40.50.970 471 704 1.8E-57 T 28-03-2018 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 PIRSF PIRSF000156 1 890 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 SUPERFAMILY SSF52518 472 699 7.51E-90 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 SUPERFAMILY SSF52518 58 466 5.9E-129 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 Gene3D G3DSA:3.40.50.970 57 470 2.2E-77 T 28-03-2018 SmaCSM2_RS08180 7dfdb3b64258500ff47b138d38a28ffb 890 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 9 888 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SmaCSM2_RS00515 8567181f618d0a0f5507708312aade68 235 Pfam PF13709 Domain of unknown function (DUF4159) 36 233 2.0E-53 T 28-03-2018 IPR025297 Domain of unknown function DUF4159 SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 Pfam PF04209 homogentisate 1,2-dioxygenase 10 431 3.2E-205 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 SUPERFAMILY SSF51182 9 433 4.56E-173 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 9 433 71.673 T 28-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 Gene3D G3DSA:2.60.120.10 278 401 1.5E-51 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 Gene3D G3DSA:2.60.120.10 199 239 4.4E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS19790 9d98fe6e20ee43773fb985828843a127 435 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 9 431 3.3E-202 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SmaCSM2_RS14510 1d48f7b82705aa1aa6fc929c988a3767 329 Gene3D G3DSA:1.25.40.10 150 226 2.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14510 1d48f7b82705aa1aa6fc929c988a3767 329 SUPERFAMILY SSF48452 71 181 1.35E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14510 1d48f7b82705aa1aa6fc929c988a3767 329 Gene3D G3DSA:1.25.40.10 44 149 2.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 SMART SM00418 20 98 2.2E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 SUPERFAMILY SSF46785 13 101 3.49E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 Gene3D G3DSA:1.10.10.10 5 98 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 Pfam PF01022 Bacterial regulatory protein, arsR family 27 72 2.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 2.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09465 ac55fde7368edf52678e550eed31273a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 2.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS13135 c819c38c3c2a756169837c8dc24d696f 137 Pfam PF13673 Acetyltransferase (GNAT) domain 41 128 8.9E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS13135 c819c38c3c2a756169837c8dc24d696f 137 SUPERFAMILY SSF55729 15 128 4.36E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS13135 c819c38c3c2a756169837c8dc24d696f 137 Gene3D G3DSA:3.40.630.30 5 137 4.8E-14 T 28-03-2018 SmaCSM2_RS02775 89b66d7742f7441ce9c0694e7af0caa5 295 SUPERFAMILY SSF53448 4 288 1.33E-91 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02775 89b66d7742f7441ce9c0694e7af0caa5 295 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 5 289 3.6E-155 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SmaCSM2_RS02775 89b66d7742f7441ce9c0694e7af0caa5 295 Pfam PF00483 Nucleotidyl transferase 5 241 1.1E-72 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SmaCSM2_RS02775 89b66d7742f7441ce9c0694e7af0caa5 295 Gene3D G3DSA:3.90.550.10 5 292 4.7E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS05765 8ee126d6ab693759634c6ac549161318 86 SUPERFAMILY SSF55229 32 81 4.84E-13 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 SmaCSM2_RS05765 8ee126d6ab693759634c6ac549161318 86 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 85 17.005 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 SmaCSM2_RS05765 8ee126d6ab693759634c6ac549161318 86 Gene3D G3DSA:3.30.1070.10 1 81 6.1E-25 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 SmaCSM2_RS05765 8ee126d6ab693759634c6ac549161318 86 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 81 2.5E-26 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 SmaCSM2_RS05765 8ee126d6ab693759634c6ac549161318 86 Pfam PF03776 Septum formation topological specificity factor MinE 13 80 5.7E-21 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 925 1036 6.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:2.130.10.10 39 174 9.6E-23 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:2.130.10.10 267 386 3.5E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:2.130.10.10 175 253 1.8E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF63829 46 249 1.9E-15 T 28-03-2018 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SMART SM00388 813 878 2.8E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1022 1035 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 PRINTS PR00344 Bacterial sensor protein C-terminal signature 998 1016 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 PRINTS PR00344 Bacterial sensor protein C-terminal signature 962 976 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 PRINTS PR00344 Bacterial sensor protein C-terminal signature 980 990 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SMART SM00387 925 1038 3.5E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:1.10.287.130 804 874 6.1E-17 T 28-03-2018 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF00512 His Kinase A (phospho-acceptor) domain 813 878 3.8E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF47384 803 879 1.65E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:2.130.10.10 564 687 6.9E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:2.130.10.10 389 563 1.9E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF63829 308 480 1.44E-14 T 28-03-2018 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF63829 234 260 1.44E-14 T 28-03-2018 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF52172 1056 1177 5.69E-28 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:3.40.50.2300 1044 1180 1.6E-29 T 28-03-2018 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF00072 Response regulator receiver domain 1060 1169 3.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF50998 487 636 1.33E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF50998 350 428 1.33E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Gene3D G3DSA:3.30.565.10 882 1043 3.7E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SMART SM00448 1058 1169 2.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF07495 Y_Y_Y domain 697 758 8.8E-12 T 28-03-2018 IPR011123 Two component regulator three Y SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 SUPERFAMILY SSF55874 867 1038 6.02E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF07494 Two component regulator propeller 45 68 0.0049 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS16270 ce717a199640aa0ed48ef04edd837ad4 1180 Pfam PF07494 Two component regulator propeller 180 202 0.0023 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 SUPERFAMILY SSF46785 9 90 6.26E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 Gene3D G3DSA:1.10.10.10 10 93 1.8E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 Gene3D G3DSA:1.10.10.10 99 170 4.6E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 SUPERFAMILY SSF46785 94 171 2.15E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 Hamap MF_01584 UPF0502 protein YceH [yceH]. 13 217 29.129 T 28-03-2018 IPR007432 Protein of unknown function DUF480 SmaCSM2_RS00345 eaddf9fdb6d52201b468e2fbffb7b1d3 217 Pfam PF04337 Protein of unknown function, DUF480 13 157 4.4E-53 T 28-03-2018 IPR007432 Protein of unknown function DUF480 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PIRSF PIRSF000097 1 267 7.8E-70 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PRINTS PR00069 Aldo-keto reductase signature 81 99 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PRINTS PR00069 Aldo-keto reductase signature 151 180 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PRINTS PR00069 Aldo-keto reductase signature 25 49 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PRINTS PR00069 Aldo-keto reductase signature 116 133 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 PRINTS PR00069 Aldo-keto reductase signature 188 212 1.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 Pfam PF00248 Aldo/keto reductase family 7 252 3.0E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 116 133 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 SUPERFAMILY SSF51430 2 261 4.19E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS21010 b3b23f882720954db2bfdb5256d7c6df 269 Gene3D G3DSA:3.20.20.100 1 265 8.5E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 Pfam PF13411 MerR HTH family regulatory protein 1 66 2.2E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 Gene3D G3DSA:1.10.1660.10 1 55 9.1E-19 T 28-03-2018 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 SMART SM00422 1 69 4.2E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 Gene3D G3DSA:1.10.1660.10 56 137 4.6E-12 T 28-03-2018 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13460 c062b797202dde57976c1a2e3a5f1142 159 SUPERFAMILY SSF46955 1 111 3.11E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 Gene3D G3DSA:2.30.110.10 1 199 1.0E-65 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 SUPERFAMILY SSF50475 2 199 1.7E-60 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 199 36.072 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 168 181 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 18 105 2.8E-28 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 PIRSF PIRSF000190 2 199 6.3E-69 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 197 9.1E-66 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS16225 e512f2b482827502dce742bbefda9e19 199 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 158 199 5.4E-13 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SmaCSM2_RS01765 a99d410d634edfdf47512a74bfe9a1fa 357 SUPERFAMILY SSF52374 9 75 2.68E-7 T 28-03-2018 SmaCSM2_RS01765 a99d410d634edfdf47512a74bfe9a1fa 357 Pfam PF13521 AAA domain 182 335 6.8E-34 T 28-03-2018 SmaCSM2_RS01765 a99d410d634edfdf47512a74bfe9a1fa 357 Gene3D G3DSA:3.40.50.620 3 189 8.6E-7 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01765 a99d410d634edfdf47512a74bfe9a1fa 357 SUPERFAMILY SSF52540 181 315 6.12E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01765 a99d410d634edfdf47512a74bfe9a1fa 357 Gene3D G3DSA:3.40.50.300 190 340 9.2E-16 T 28-03-2018 SmaCSM2_RS20135 6c86c9b6a40b65dc89865ae1a69b5a98 390 Pfam PF00144 Beta-lactamase 55 369 3.3E-43 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS20135 6c86c9b6a40b65dc89865ae1a69b5a98 390 SUPERFAMILY SSF56601 37 370 1.1E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS20135 6c86c9b6a40b65dc89865ae1a69b5a98 390 Gene3D G3DSA:3.40.710.10 33 384 1.8E-52 T 28-03-2018 SmaCSM2_RS20135 6c86c9b6a40b65dc89865ae1a69b5a98 390 ProSitePatterns PS00336 Beta-lactamase class-C active site. 90 97 - T 28-03-2018 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 SmaCSM2_RS16730 88b420c57213232ff923aad6063600bc 173 Gene3D G3DSA:3.40.630.30 1 172 9.9E-34 T 28-03-2018 SmaCSM2_RS16730 88b420c57213232ff923aad6063600bc 173 Pfam PF00583 Acetyltransferase (GNAT) family 30 146 6.3E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS16730 88b420c57213232ff923aad6063600bc 173 SUPERFAMILY SSF55729 1 159 3.09E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 SUPERFAMILY SSF55174 331 400 6.28E-15 T 28-03-2018 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 Gene3D G3DSA:3.10.290.10 322 400 6.8E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 399 2.8E-111 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 SUPERFAMILY SSF52374 4 315 9.25E-90 T 28-03-2018 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 400 45.684 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 2.7E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 2.7E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 2.7E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 2.7E-25 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 Pfam PF00579 tRNA synthetases class I (W and Y) 31 315 9.7E-71 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 Gene3D G3DSA:1.10.240.10 219 321 1.8E-17 T 28-03-2018 SmaCSM2_RS01695 c9646d7e2d77d7a8df3a0ba412c8bee0 403 Gene3D G3DSA:3.40.50.620 1 218 2.1E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.8E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 Gene3D G3DSA:1.10.10.10 9 91 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 Gene3D G3DSA:3.40.190.10 96 184 1.6E-13 T 28-03-2018 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 SUPERFAMILY SSF53850 97 301 3.8E-42 T 28-03-2018 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 SUPERFAMILY SSF46785 10 117 4.21E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 Gene3D G3DSA:3.40.190.10 185 269 6.3E-19 T 28-03-2018 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12835 a5e952a1acf5d984d5d1740e2330ff42 309 Pfam PF03466 LysR substrate binding domain 96 298 2.0E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 458 642 8.9E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 Gene3D G3DSA:1.20.1170.10 42 287 0.009 T 28-03-2018 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 Gene3D G3DSA:1.10.287.1060 367 453 0.0078 T 28-03-2018 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 541 570 7.6E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 7.6E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 512 539 7.6E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 SUPERFAMILY SSF58104 376 676 7.19E-68 T 28-03-2018 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 Gene3D G3DSA:1.10.287.950 454 678 3.1E-51 T 28-03-2018 SmaCSM2_RS16480 f56c41255661fb4e12355593e88f5d98 678 SMART SM00283 414 675 9.3E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 21 383 5.0E-134 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 Gene3D G3DSA:3.20.20.70 33 385 2.4E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 22 379 74.68 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 PIRSF PIRSF006004 16 393 1.2E-146 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 SUPERFAMILY SSF102114 123 349 1.31E-15 T 28-03-2018 SmaCSM2_RS09045 307cf25cce9a3111a3b2f21b1f877b5d 401 Pfam PF04055 Radical SAM superfamily 129 301 1.2E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Pfam PF00912 Transglycosylase 168 347 1.3E-51 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Pfam PF00905 Penicillin binding protein transpeptidase domain 442 683 2.2E-17 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Gene3D G3DSA:3.40.710.10 374 749 3.9E-84 T 28-03-2018 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 PIRSF PIRSF002799 6 788 1.6E-273 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Gene3D G3DSA:3.30.2060.10 76 161 3.8E-20 T 28-03-2018 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Gene3D G3DSA:1.10.3810.10 162 364 5.3E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 SUPERFAMILY SSF53955 166 369 6.75E-55 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 32 762 1.3E-285 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 Pfam PF14814 Bifunctional transglycosylase second domain 77 161 9.0E-21 T 28-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 SUPERFAMILY SSF56601 329 351 1.45E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS16525 aa940d841e73bd198d47dca08d23e60e 813 SUPERFAMILY SSF56601 381 765 1.45E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 SUPERFAMILY SSF52343 703 840 5.63E-31 T 28-03-2018 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 709 728 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 746 757 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 646 653 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Gene3D G3DSA:3.40.50.80 700 839 4.0E-20 T 28-03-2018 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 SUPERFAMILY SSF63380 536 701 7.32E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 SUPERFAMILY SSF52218 381 525 9.85E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Pfam PF00175 Oxidoreductase NAD-binding domain 710 814 3.5E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00369 Flavodoxin signature 463 473 5.4E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00369 Flavodoxin signature 432 443 5.4E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 PRINTS PR00369 Flavodoxin signature 384 397 5.4E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Gene3D G3DSA:2.40.30.10 526 692 7.1E-14 T 28-03-2018 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Pfam PF00258 Flavodoxin 385 507 7.2E-22 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Gene3D G3DSA:3.40.50.360 357 525 3.6E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS19250 63dc9084e7f762569f4f6edc17a95b8e 840 Pfam PF03929 PepSY-associated TM region 7 357 1.5E-58 T 28-03-2018 IPR005625 PepSY-associated TM protein SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 Gene3D G3DSA:1.10.10.10 23 93 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 SUPERFAMILY SSF47979 94 149 1.26E-13 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 SUPERFAMILY SSF46785 35 93 2.41E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 SMART SM00529 55 152 6.8E-33 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 Gene3D G3DSA:1.10.60.10 94 148 2.4E-18 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 35 91 2.8E-13 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 SmaCSM2_RS12580 2aedf28f40454dc1f553c86e05150728 156 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 94 149 2.0E-12 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SmaCSM2_RS21210 be43e0cd14a9d493391e57e8d54deeaf 159 Pfam PF04239 Protein of unknown function (DUF421) 95 157 7.6E-12 T 28-03-2018 IPR007353 Protein of unknown function DUF421 SmaCSM2_RS21210 be43e0cd14a9d493391e57e8d54deeaf 159 Gene3D G3DSA:3.30.240.20 89 158 8.6E-19 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain SmaCSM2_RS01455 d7a4c8313e93a13977235f489869fbeb 229 Gene3D G3DSA:3.40.50.300 1 225 5.2E-65 T 28-03-2018 SmaCSM2_RS01455 d7a4c8313e93a13977235f489869fbeb 229 SMART SM00382 33 221 4.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS01455 d7a4c8313e93a13977235f489869fbeb 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS01455 d7a4c8313e93a13977235f489869fbeb 229 SUPERFAMILY SSF52540 4 224 1.73E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01455 d7a4c8313e93a13977235f489869fbeb 229 Pfam PF00005 ABC transporter 24 172 2.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 16 266 34.203 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 Gene3D G3DSA:3.20.20.70 4 269 1.9E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 Pfam PF00290 Tryptophan synthase alpha chain 10 259 2.2E-83 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 10 263 4.2E-73 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 SUPERFAMILY SSF51366 4 251 4.47E-84 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS15235 63fa056e38df4e86336d8ad96c2ef8b1 269 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 50 63 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 Pfam PF00266 Aminotransferase class-V 38 406 2.8E-143 T 28-03-2018 IPR000192 Aminotransferase class V domain SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 229 248 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 SUPERFAMILY SSF53383 17 415 9.35E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 20 417 3.1E-171 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 Gene3D G3DSA:3.40.640.10 48 294 1.0E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS05305 ca69339caa237aeaab245d2ba53f5702 418 Gene3D G3DSA:3.90.1150.10 295 413 5.5E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS20275 8124c28cced6b0ef5cf4a045f146293d 100 SUPERFAMILY SSF54909 1 98 6.97E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS20275 8124c28cced6b0ef5cf4a045f146293d 100 Gene3D G3DSA:3.30.70.100 1 93 8.4E-15 T 28-03-2018 SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 SUPERFAMILY SSF110997 350 421 1.31E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 Pfam PF05036 Sporulation related domain 348 421 2.6E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 131 229 3.3E-42 T 28-03-2018 IPR012997 Rare lipoprotein A SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 Gene3D G3DSA:3.30.70.1070 343 420 5.9E-10 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 Pfam PF03330 Lytic transglycolase 129 218 7.8E-23 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 14 221 24.457 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 SUPERFAMILY SSF50685 128 214 6.98E-9 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS18345 f7870ce73ebd3e6fb25ad416f43ac1b7 423 Gene3D G3DSA:2.40.40.10 110 220 1.5E-23 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF00990 Diguanylate cyclase, GGDEF domain 849 1004 8.8E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 SUPERFAMILY SSF63829 60 222 8.94E-11 T 28-03-2018 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Gene3D G3DSA:2.130.10.10 311 431 3.4E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Gene3D G3DSA:2.130.10.10 52 265 4.9E-24 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Gene3D G3DSA:2.130.10.10 443 787 6.5E-17 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 SUPERFAMILY SSF63829 272 505 2.94E-16 T 28-03-2018 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 SUPERFAMILY SSF55073 852 1005 2.67E-44 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07494 Two component regulator propeller 399 420 0.0068 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07494 Two component regulator propeller 273 294 0.005 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07494 Two component regulator propeller 482 503 0.0069 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07494 Two component regulator propeller 441 463 0.0085 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07494 Two component regulator propeller 59 81 0.0097 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 SUPERFAMILY SSF63829 444 665 3.27E-8 T 28-03-2018 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 844 1006 3.3E-42 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Gene3D G3DSA:3.30.70.270 830 1007 2.2E-51 T 28-03-2018 SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 SMART SM00267 836 1008 2.2E-50 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06835 1f2764df6e1ffc8b88d532852d609555 1008 Pfam PF07495 Y_Y_Y domain 702 764 9.0E-15 T 28-03-2018 IPR011123 Two component regulator three Y SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 404 1.0E-5 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 623 637 1.0E-5 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 Gene3D G3DSA:3.20.20.70 8 369 2.0E-105 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 12 335 2.4E-76 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 503 521 2.0E-10 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 383 402 2.0E-10 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 622 638 2.0E-10 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 Gene3D G3DSA:3.40.50.720 370 482 2.0E-24 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 Gene3D G3DSA:3.50.50.60 483 629 1.3E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 SUPERFAMILY SSF51971 339 524 8.24E-43 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 SUPERFAMILY SSF51905 473 631 2.39E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 SUPERFAMILY SSF51395 8 368 1.83E-105 T 28-03-2018 SmaCSM2_RS04200 b69b8929c2a7f6f2b469a524bb288e23 676 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 381 654 1.6E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 SUPERFAMILY SSF52540 381 574 1.56E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 Gene3D G3DSA:1.20.1560.10 1 349 3.8E-34 T 28-03-2018 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 SUPERFAMILY SSF90123 27 347 5.1E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 Gene3D G3DSA:3.40.50.300 368 577 1.3E-54 T 28-03-2018 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 SMART SM00382 396 571 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 38 565 6.3E-158 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 Pfam PF00664 ABC transporter transmembrane region 44 285 1.7E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS14530 08278dd42bd9328de72962ad04694669 581 Pfam PF00005 ABC transporter 387 525 2.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1135 1161 7.1E-7 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF54523 1719 1834 5.18E-23 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:1.20.5.1230 157 505 4.5E-12 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF101967 1082 1200 8.76E-18 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 826 992 1.4E-18 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF101967 1587 1676 3.01E-19 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1026 1055 2.3E-4 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 966 1002 3.2E-9 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1179 1219 7.0E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1536 1568 1.2E-5 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1655 1696 2.0E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1710 1734 2.3E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1351 1395 9.0E-8 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1234 1273 3.7E-4 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:3.30.1300.30 1729 1834 2.5E-22 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:1.20.120.20 506 673 6.7E-10 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF101967 1444 1557 7.06E-15 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 993 1057 0.0014 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 1206 1251 4.1E-4 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 1074 1205 4.1E-18 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 1683 1728 5.1E-8 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:2.150.10.10 1558 1682 3.8E-21 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:1.20.5.170 1357 1429 3.0E-9 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:1.20.5.170 1252 1322 1.3E-8 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF101967 1691 1729 2.75E-6 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 SUPERFAMILY SSF101967 830 988 4.45E-16 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Gene3D G3DSA:3.30.1300.30 1430 1545 1.2E-12 T 28-03-2018 SmaCSM2_RS12700 984036dc2cb97a7d4ab438c7b2948127 1834 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 1.0E-8 T 28-03-2018 IPR024973 ESPR domain SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 Gene3D G3DSA:3.40.605.10 11 283 6.9E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 Gene3D G3DSA:3.40.309.10 284 480 2.5E-71 T 28-03-2018 SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 Pfam PF00171 Aldehyde dehydrogenase family 32 493 9.7E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 SUPERFAMILY SSF53720 12 497 1.23E-165 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS06985 5be504473090c760590d5f8538bbe663 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52540 345 497 3.73E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52540 128 211 3.73E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52540 826 848 3.73E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52540 549 789 3.73E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52540 22 80 3.73E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Pfam PF00580 UvrD/REP helicase N-terminal domain 23 462 1.4E-53 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Pfam PF13361 UvrD-like helicase C-terminal domain 651 847 4.2E-16 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Pfam PF13361 UvrD-like helicase C-terminal domain 469 643 8.5E-7 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Pfam PF12705 PD-(D/E)XK nuclease superfamily 976 1156 2.4E-5 T 28-03-2018 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Gene3D G3DSA:3.90.320.10 899 1215 4.9E-75 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 SUPERFAMILY SSF52980 910 1209 5.36E-57 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Gene3D G3DSA:3.40.50.300 18 470 1.7E-41 T 28-03-2018 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Gene3D G3DSA:3.40.50.300 471 614 2.4E-14 T 28-03-2018 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Gene3D G3DSA:3.40.50.300 623 858 4.1E-24 T 28-03-2018 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 19 1207 1.1E-217 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 SmaCSM2_RS21620 f30f9129063e03fc2cc24dbd36f7a106 1226 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 14 1208 19.126 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 SmaCSM2_RS02550 b5174ce8dac2ad5f5c50c3a357f4c0bc 589 Pfam PF00578 AhpC/TSA family 286 389 3.4E-9 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS02550 b5174ce8dac2ad5f5c50c3a357f4c0bc 589 Gene3D G3DSA:3.40.30.10 253 423 1.3E-24 T 28-03-2018 SmaCSM2_RS02550 b5174ce8dac2ad5f5c50c3a357f4c0bc 589 SUPERFAMILY SSF52833 266 407 4.07E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS02550 b5174ce8dac2ad5f5c50c3a357f4c0bc 589 Gene3D G3DSA:2.60.120.260 441 588 6.0E-44 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS02550 b5174ce8dac2ad5f5c50c3a357f4c0bc 589 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 7 187 4.5E-12 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF81767 227 364 1.83E-43 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 829 19.993 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Pfam PF01043 SecA preprotein cross-linking domain 233 354 4.7E-38 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF52540 412 615 6.99E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SMART SM00957 6 398 0.0 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 101 115 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 170 190 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 372 389 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 409 422 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 335 357 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 117 127 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 PRINTS PR00906 SecA protein signature 63 87 3.8E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 815 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 ProSitePatterns PS01312 SecA family signature. 496 511 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Pfam PF02810 SEC-C motif 890 908 1.1E-10 T 28-03-2018 IPR004027 SEC-C motif SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SMART SM00958 228 354 6.2E-76 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Gene3D G3DSA:3.40.50.300 413 644 1.9E-54 T 28-03-2018 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF81886 886 898 1.83E-78 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF81886 618 837 1.83E-78 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Pfam PF07516 SecA Wing and Scaffold domain 615 826 6.3E-65 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Gene3D G3DSA:3.40.50.300 295 412 1.8E-8 T 28-03-2018 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Gene3D G3DSA:3.40.50.300 9 270 1.1E-58 T 28-03-2018 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF52540 6 228 1.23E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 SUPERFAMILY SSF52540 364 411 1.23E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Pfam PF07517 SecA DEAD-like domain 7 398 5.9E-134 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SmaCSM2_RS03305 27aa5ec5c6a59f956d87e7258e8e6481 910 Gene3D G3DSA:1.10.3060.10 645 828 8.8E-55 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82693 571 675 9.42E-30 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:1.20.1640.10 822 1034 7.2E-34 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:3.30.70.1430 573 673 3.0E-18 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1039 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82714 727 814 2.62E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82693 135 182 1.96E-27 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82693 274 330 1.96E-27 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:3.30.2090.10 180 275 3.8E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82866 296 497 9.81E-47 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:3.30.70.1430 38 140 8.2E-29 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82693 38 133 2.41E-27 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Pfam PF00873 AcrB/AcrD/AcrF family 1 1030 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:3.30.70.1440 677 773 1.5E-17 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82714 182 272 3.14E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 627 641 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 PRINTS PR00702 Acriflavin resistance protein family signature 558 575 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 Gene3D G3DSA:1.20.1640.10 286 510 8.1E-42 T 28-03-2018 SmaCSM2_RS18435 02c38a2cfa1ca233da9c29d0929a7ed7 1040 SUPERFAMILY SSF82866 811 1035 4.58E-40 T 28-03-2018 SmaCSM2_RS09055 1add9bc31f306b488760bdb0c54c960d 290 Pfam PF13413 Helix-turn-helix domain 19 77 3.1E-20 T 28-03-2018 SmaCSM2_RS09055 1add9bc31f306b488760bdb0c54c960d 290 Gene3D G3DSA:1.10.260.40 3 86 3.4E-10 T 28-03-2018 SmaCSM2_RS09055 1add9bc31f306b488760bdb0c54c960d 290 Pfam PF13464 Domain of unknown function (DUF4115) 206 279 2.9E-19 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 SmaCSM2_RS09055 1add9bc31f306b488760bdb0c54c960d 290 SMART SM00530 19 80 1.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS09055 1add9bc31f306b488760bdb0c54c960d 290 SUPERFAMILY SSF47413 17 82 1.25E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Gene3D G3DSA:3.40.50.300 2 201 1.1E-31 T 28-03-2018 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SMART SM00956 405 508 5.7E-55 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 457 2.2E-157 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SUPERFAMILY SSF47819 528 599 3.05E-22 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 599 1.0E-262 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Pfam PF00271 Helicase conserved C-terminal domain 219 323 8.3E-15 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Pfam PF00570 HRDC domain 530 597 7.0E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Gene3D G3DSA:3.40.50.300 202 349 2.7E-30 T 28-03-2018 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SUPERFAMILY SSF52540 201 451 3.4E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Gene3D G3DSA:1.10.150.80 511 600 4.1E-24 T 28-03-2018 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SMART SM00487 15 211 2.6E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Pfam PF00270 DEAD/DEAH box helicase 23 178 4.6E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SUPERFAMILY SSF52540 6 190 6.09E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SMART SM00341 527 600 5.7E-12 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Pfam PF16124 RecQ zinc-binding 336 398 3.2E-20 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Pfam PF09382 RQC domain 400 511 5.2E-42 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 Gene3D G3DSA:1.10.10.10 350 510 1.0E-51 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16560 1be82403eacf77681b28860846396c90 601 SMART SM00490 243 324 9.4E-24 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 SUPERFAMILY SSF55315 37 109 1.29E-12 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 SUPERFAMILY SSF75217 123 274 5.89E-35 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 41 109 5.8E-14 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 SMART SM00967 40 115 3.1E-14 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 Gene3D G3DSA:3.30.1330.30 32 110 8.7E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 Gene3D G3DSA:3.40.1280.10 122 277 6.3E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS17085 149071189dd7c5fe625b2cdf717f004a 278 Pfam PF00588 SpoU rRNA Methylase family 130 269 1.5E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 Gene3D G3DSA:3.40.1280.10 1 245 7.7E-82 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 PIRSF PIRSF015601 3 244 7.6E-63 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 Pfam PF04452 RNA methyltransferase 18 239 1.3E-73 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 15 244 1.4E-60 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 SUPERFAMILY SSF75217 74 244 3.72E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS16460 820ff1d5730ebef7db1dd4f38652c670 245 SUPERFAMILY SSF88697 4 71 1.99E-16 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 Gene3D G3DSA:3.40.190.10 113 205 1.2E-29 T 28-03-2018 SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 27 243 7.2E-55 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 Gene3D G3DSA:3.40.190.10 16 112 4.6E-18 T 28-03-2018 SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 SUPERFAMILY SSF53850 21 245 2.1E-64 T 28-03-2018 SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 PIRSF PIRSF004846 2 247 1.8E-70 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SmaCSM2_RS12255 df08fb61f52e7207894e07db1054aab6 247 Pfam PF13531 Bacterial extracellular solute-binding protein 22 244 1.4E-50 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 PIRSF PIRSF006288 10 872 1.5E-276 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 36 865 8.8E-226 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Gene3D G3DSA:1.20.120.330 176 322 7.4E-23 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Gene3D G3DSA:3.30.460.10 33 173 2.7E-21 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 SUPERFAMILY SSF81301 18 174 2.75E-18 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Pfam PF01966 HD domain 452 559 5.0E-14 T 28-03-2018 IPR006674 HD domain SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Gene3D G3DSA:3.30.70.260 688 766 3.7E-5 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 875 259.892 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Pfam PF08335 GlnD PII-uridylyltransferase 179 317 6.5E-32 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Gene3D G3DSA:3.30.70.260 791 868 6.9E-11 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 SUPERFAMILY SSF109604 420 571 2.35E-13 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 SUPERFAMILY SSF81593 186 318 7.77E-10 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 SUPERFAMILY SSF55021 795 858 6.66E-10 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Pfam PF01842 ACT domain 801 858 2.5E-6 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 SMART SM00471 447 594 3.1E-8 T 28-03-2018 IPR003607 HD/PDEase domain SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Gene3D G3DSA:1.10.3090.10 375 628 1.3E-40 T 28-03-2018 SmaCSM2_RS06690 35debe42b75af5552e2456b3fd6f491d 875 Pfam PF01909 Nucleotidyltransferase domain 72 104 3.1E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 Pfam PF00593 TonB dependent receptor 366 958 1.0E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 SUPERFAMILY SSF56935 497 646 2.53E-94 T 28-03-2018 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 SUPERFAMILY SSF56935 34 226 2.53E-94 T 28-03-2018 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 SUPERFAMILY SSF56935 296 344 2.53E-94 T 28-03-2018 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 SUPERFAMILY SSF56935 691 962 2.53E-94 T 28-03-2018 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 SUPERFAMILY SSF56935 373 435 2.53E-94 T 28-03-2018 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 Gene3D G3DSA:2.40.170.20 168 962 2.1E-72 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 Gene3D G3DSA:2.170.130.10 24 167 4.0E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16365 bef542733990a52206b18c05b45bf4c2 962 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 161 1.3E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 SUPERFAMILY SSF48208 307 751 6.63E-20 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 40 795 1.1E-147 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 Gene3D G3DSA:3.30.2080.10 661 808 1.1E-51 T 28-03-2018 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 Pfam PF07971 Glycosyl hydrolase family 92 270 793 2.9E-147 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 Gene3D G3DSA:1.20.1050.60 381 477 3.7E-21 T 28-03-2018 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 Gene3D G3DSA:2.70.98.10 39 358 7.1E-75 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS09635 2b4406cadf3f4129d0682907ae69eeff 821 Gene3D G3DSA:1.20.1610.10 478 660 4.9E-48 T 28-03-2018 SmaCSM2_RS08245 45e1e15c05a536bcd7e32a4ede8df3b5 233 Pfam PF02678 Pirin 10 119 3.0E-33 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SmaCSM2_RS08245 45e1e15c05a536bcd7e32a4ede8df3b5 233 Gene3D G3DSA:2.60.120.10 136 233 4.5E-32 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS08245 45e1e15c05a536bcd7e32a4ede8df3b5 233 SUPERFAMILY SSF51182 1 231 1.4E-77 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS08245 45e1e15c05a536bcd7e32a4ede8df3b5 233 Gene3D G3DSA:2.60.120.10 11 135 7.3E-47 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS08245 45e1e15c05a536bcd7e32a4ede8df3b5 233 PIRSF PIRSF006232 1 230 7.0E-53 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 SUPERFAMILY SSF51905 1 293 8.29E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 SUPERFAMILY SSF51905 392 410 8.29E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 Gene3D G3DSA:3.40.50.20 1 45 2.5E-8 T 28-03-2018 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 1.4E-8 T 28-03-2018 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 1.4E-8 T 28-03-2018 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 Pfam PF01593 Flavin containing amine oxidoreductase 15 407 1.6E-31 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SmaCSM2_RS02725 c13450e5f76efaeffc99979e251c85ec 433 Gene3D G3DSA:3.90.660.20 46 379 3.8E-19 T 28-03-2018 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 Gene3D G3DSA:3.90.180.10 266 329 0.054 T 28-03-2018 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 SMART SM00829 11 327 4.8E-31 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 Pfam PF00107 Zinc-binding dehydrogenase 158 281 1.2E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 3.4E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 SUPERFAMILY SSF51735 118 277 7.45E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 SUPERFAMILY SSF50129 3 151 8.65E-35 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 Gene3D G3DSA:3.40.50.720 148 265 4.7E-23 T 28-03-2018 SmaCSM2_RS20185 7d63718b17eb551174c67fd68f7acc66 329 Gene3D G3DSA:3.90.180.10 2 147 2.9E-39 T 28-03-2018 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 6 62 3.7E-20 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 SUPERFAMILY SSF50104 5 64 9.63E-16 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 TIGRFAM TIGR00038 efp: translation elongation factor P 6 187 4.8E-71 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 PIRSF PIRSF005901 2 188 2.6E-60 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Gene3D G3DSA:2.40.50.140 131 186 1.5E-26 T 28-03-2018 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 SMART SM00841 131 186 1.2E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 SUPERFAMILY SSF50249 130 187 1.71E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 SMART SM01185 69 123 5.9E-20 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 SUPERFAMILY SSF50249 70 128 1.41E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 7.1E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 46.849 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Gene3D G3DSA:2.30.30.30 4 63 7.8E-19 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 123 2.3E-19 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SmaCSM2_RS14695 9a423c526b6bf38e25c7fda59d64ec89 188 Gene3D G3DSA:2.40.50.140 67 129 2.3E-23 T 28-03-2018 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 SUPERFAMILY SSF52540 330 577 1.74E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 Pfam PF00664 ABC transporter transmembrane region 25 293 5.5E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 11 579 9.1E-220 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 Pfam PF00005 ABC transporter 358 506 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 SUPERFAMILY SSF90123 13 326 9.68E-64 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 SMART SM00382 367 552 2.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 Gene3D G3DSA:3.40.50.300 328 582 3.6E-72 T 28-03-2018 SmaCSM2_RS07315 80df8686ea249a4ed110ffdb489b1bc8 582 Gene3D G3DSA:1.20.1560.10 6 327 2.3E-56 T 28-03-2018 SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 Pfam PF00589 Phage integrase family 215 391 9.9E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 SUPERFAMILY SSF56349 99 401 1.8E-47 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 Pfam PF13356 Arm DNA-binding domain 3 87 1.6E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 Gene3D G3DSA:1.10.443.10 211 401 4.8E-18 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 99 150 6.4E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SmaCSM2_RS07400 69af1275939b50a3009a5bfc750fdb2b 647 Gene3D G3DSA:1.10.150.130 88 210 1.8E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS09865 63a46ea5e213e5755b71d78d8bfcda95 286 Gene3D G3DSA:2.20.25.10 249 284 2.4E-5 T 28-03-2018 SmaCSM2_RS09865 63a46ea5e213e5755b71d78d8bfcda95 286 Pfam PF04397 LytTr DNA-binding domain 190 283 7.1E-21 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS09865 63a46ea5e213e5755b71d78d8bfcda95 286 PIRSF PIRSF031767 2 286 7.9E-81 T 28-03-2018 IPR012379 LytTR MHYE transcriptional regulator, putative SmaCSM2_RS09865 63a46ea5e213e5755b71d78d8bfcda95 286 SMART SM00850 187 284 1.7E-30 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS09865 63a46ea5e213e5755b71d78d8bfcda95 286 Gene3D G3DSA:2.40.50.40 178 245 7.0E-10 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Pfam PF11941 Domain of unknown function (DUF3459) 448 532 7.1E-7 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Gene3D G3DSA:3.20.20.80 345 463 3.2E-18 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Gene3D G3DSA:3.90.400.10 121 171 5.3E-26 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Pfam PF00128 Alpha amylase, catalytic domain 29 377 2.0E-86 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Gene3D G3DSA:3.20.20.470 172 344 7.0E-33 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 SUPERFAMILY SSF51011 463 535 1.08E-7 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Gene3D G3DSA:3.20.20.80 2 120 1.2E-41 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 Gene3D G3DSA:2.60.40.1180 464 537 1.6E-6 T 28-03-2018 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 SMART SM00642 14 402 9.7E-114 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SmaCSM2_RS05405 dc2a65061923c38ca399ebdedff9a9da 537 SUPERFAMILY SSF51445 5 460 1.62E-132 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 Pfam PF01025 GrpE 11 169 6.1E-48 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 ProSitePatterns PS01071 grpE protein signature. 125 168 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 Hamap MF_01151 Protein GrpE [grpE]. 2 170 19.389 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 SUPERFAMILY SSF58014 23 114 4.84E-23 T 28-03-2018 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 PRINTS PR00773 GrpE protein signature 122 137 3.4E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 PRINTS PR00773 GrpE protein signature 42 58 3.4E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 PRINTS PR00773 GrpE protein signature 149 168 3.4E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 PRINTS PR00773 GrpE protein signature 70 85 3.4E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 Gene3D G3DSA:3.90.20.20 9 112 2.3E-22 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 SUPERFAMILY SSF51064 117 170 4.58E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SmaCSM2_RS08745 aedd7deb80599dc3e0120c07d278bd00 171 Gene3D G3DSA:2.30.22.10 114 170 3.0E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 359 44.997 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Gene3D G3DSA:3.30.1360.120 2 123 6.8E-31 T 28-03-2018 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 PIRSF PIRSF006487 1 365 1.5E-86 T 28-03-2018 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Gene3D G3DSA:3.30.1360.120 124 236 9.7E-29 T 28-03-2018 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Gene3D G3DSA:4.10.1250.10 237 280 1.2E-17 T 28-03-2018 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 SUPERFAMILY SSF103025 3 281 5.81E-92 T 28-03-2018 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Gene3D G3DSA:2.40.30.110 282 367 6.8E-18 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 358 3.4E-129 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 353 1.3E-19 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 SUPERFAMILY SSF101790 274 361 5.4E-22 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SmaCSM2_RS16425 e6864ddd4292561c0586965b83ca9820 370 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 259 4.4E-88 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 181 1.2E-9 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SMART SM00304 211 263 3.8E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SMART SM00304 392 444 9.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SMART SM00304 302 353 2.3 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Gene3D G3DSA:1.20.120.30 39 171 2.2E-6 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SUPERFAMILY SSF158472 211 261 3.79E-9 T 28-03-2018 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 505 659 1.7E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SMART SM00283 445 692 4.0E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Pfam PF00672 HAMP domain 211 259 6.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Gene3D G3DSA:1.10.287.950 501 696 4.0E-47 T 28-03-2018 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 Gene3D G3DSA:1.10.287.950 210 500 2.9E-24 T 28-03-2018 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 466 495 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 543 570 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 620 649 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 572 601 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS06160 b063e1e7527af6bbdbe34acbf7ac7222 740 SUPERFAMILY SSF58104 412 693 2.88E-72 T 28-03-2018 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Gene3D G3DSA:3.30.160.40 219 302 1.9E-21 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 37.161 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Gene3D G3DSA:3.40.190.10 1 104 7.9E-42 T 28-03-2018 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 SUPERFAMILY SSF54782 218 302 4.45E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 SUPERFAMILY SSF53850 2 216 1.94E-80 T 28-03-2018 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Gene3D G3DSA:3.40.190.10 105 197 3.0E-35 T 28-03-2018 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 224 293 2.8E-16 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 9.7E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 9.7E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 9.7E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 9.7E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 9.7E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 3.9E-102 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 209 9.3E-74 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS18785 2397863a919d860abc1dfc9c9fd2fec8 303 PIRSF PIRSF001438 1 303 1.5E-114 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 Gene3D G3DSA:3.20.20.70 6 317 6.9E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 222 313 1.7E-19 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 Pfam PF04055 Radical SAM superfamily 51 203 7.3E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 PIRSF PIRSF001619 1 320 4.6E-130 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 SMART SM00876 222 314 6.8E-49 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 Hamap MF_01694 Biotin synthase [bioB]. 7 315 41.853 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 SUPERFAMILY SSF102114 7 315 3.53E-92 T 28-03-2018 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 SMART SM00729 45 257 7.7E-35 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS20645 ac4eca9c15467087a346185c123ba905 347 TIGRFAM TIGR00433 bioB: biotin synthase 16 313 1.8E-121 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF03725 3' exoribonuclease family, domain 2 460 529 9.8E-7 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF03725 3' exoribonuclease family, domain 2 146 209 4.4E-12 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SMART SM00322 553 618 1.0E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF55666 451 550 1.35E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF50249 609 695 2.74E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF46915 238 321 3.14E-16 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Gene3D G3DSA:3.30.230.70 310 560 1.2E-57 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF54211 298 489 2.83E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF00013 KH domain 558 615 1.1E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF54791 553 630 1.26E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 694 30.449 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Gene3D G3DSA:2.40.50.140 616 697 4.7E-26 T 28-03-2018 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF55666 144 233 9.12E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF00575 S1 RNA binding domain 620 691 3.6E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SUPERFAMILY SSF54211 4 143 3.44E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 693 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Gene3D G3DSA:3.30.1370.10 561 615 1.1E-15 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Gene3D G3DSA:1.10.10.400 250 309 2.9E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF01138 3' exoribonuclease family, domain 1 15 143 5.2E-19 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 1.0E-22 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Gene3D G3DSA:3.30.230.70 13 249 1.9E-48 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 320 1.6E-15 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 PIRSF PIRSF005499 1 702 5.9E-294 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SmaCSM2_RS15065 83cfd96f19226869f20faaa5e36e2969 702 SMART SM00316 621 691 4.3E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 SUPERFAMILY SSF52172 2 128 7.4E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 Gene3D G3DSA:1.10.10.10 124 212 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 Pfam PF00072 Response regulator receiver domain 5 114 8.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 Gene3D G3DSA:3.40.50.2300 1 123 2.9E-28 T 28-03-2018 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 SMART SM00448 2 116 2.4E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 SMART SM00421 147 204 1.9E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 3.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS21390 8e5905828ff275333714f2c78648b068 221 SUPERFAMILY SSF46894 141 207 2.14E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 Gene3D G3DSA:3.30.499.10 1 161 3.1E-37 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 5 466 2.8E-193 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 Gene3D G3DSA:3.40.1060.10 162 296 9.7E-41 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 SUPERFAMILY SSF53732 4 466 1.31E-152 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 Gene3D G3DSA:3.30.499.10 325 472 2.4E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 Pfam PF00330 Aconitase family (aconitate hydratase) 10 458 2.5E-140 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 4 467 52.815 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 116 124 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 141 156 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 127 140 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 344 355 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 400 413 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 203 216 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 217 230 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 294 308 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 PRINTS PR00415 Aconitase family signature 90 103 1.8E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17770 023064ed47ea13d054519e52adf9dfb1 472 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SmaCSM2_RS07485 e1bc9cc5d274f1e3687663d793ef5223 276 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 3 274 7.6E-126 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 SmaCSM2_RS07485 e1bc9cc5d274f1e3687663d793ef5223 276 Pfam PF00756 Putative esterase 21 267 1.8E-64 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SmaCSM2_RS07485 e1bc9cc5d274f1e3687663d793ef5223 276 Gene3D G3DSA:3.40.50.1820 1 275 1.1E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS07485 e1bc9cc5d274f1e3687663d793ef5223 276 SUPERFAMILY SSF53474 1 275 4.97E-91 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 352 47.33 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 Gene3D G3DSA:3.40.718.10 1 353 2.6E-127 T 28-03-2018 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 347 2.8E-148 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 SMART SM01329 4 348 2.0E-186 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 SUPERFAMILY SSF53659 4 352 4.5E-119 T 28-03-2018 SmaCSM2_RS17780 9fc71e7940833d9581b69248ec051ee6 353 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 348 3.5E-135 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 SMART SM00322 60 125 3.1E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.188 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 Gene3D G3DSA:3.30.300.20 17 107 2.4E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 8.2E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 Pfam PF07650 KH domain 38 111 1.7E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 SUPERFAMILY SSF54814 2 106 7.33E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 SUPERFAMILY SSF54821 108 206 2.09E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 Gene3D G3DSA:3.30.1140.32 108 207 4.7E-38 T 28-03-2018 SmaCSM2_RS04020 2e64a118c10c4cb6f76ffb93afefadb0 244 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 4.3E-95 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:3.30.565.10 1780 1967 2.9E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.20.120.160 282 457 5.7E-11 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.20.120.160 1461 1630 7.0E-27 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.20.120.160 786 962 5.3E-25 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.20.120.160 967 1108 1.8E-11 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.20.120.160 15 142 1.0E-11 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF50341 1965 2095 4.84E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF00072 Response regulator receiver domain 2121 2231 1.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00448 2119 2232 2.9E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF47226 290 408 1.41E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF47226 13 133 4.32E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00073 1464 1561 1.1E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00073 973 1065 0.34 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00073 790 887 7.4E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF52172 2121 2240 1.57E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF01584 CheW-like domain 1970 2098 1.8E-20 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:1.10.287.560 1642 1779 7.9E-12 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00387 1825 1966 6.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF01627 Hpt domain 1466 1559 6.5E-14 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF01627 Hpt domain 793 883 1.3E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF01627 Hpt domain 13 111 3.0E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF01627 Hpt domain 973 1069 3.1E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF55874 1782 1963 5.24E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:2.30.30.40 2033 2096 7.9E-18 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF47226 789 900 6.02E-25 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1870 1884 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1950 1963 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1926 1944 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF47226 970 1092 2.35E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 1644 1779 4.3E-6 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM00260 1958 2096 1.6E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1829 1965 6.6E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SUPERFAMILY SSF47226 1464 1578 3.93E-24 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 Gene3D G3DSA:3.40.50.2300 2113 2243 8.4E-35 T 28-03-2018 SmaCSM2_RS16475 915d4b28c584561cea77f40eb4e421da 2243 SMART SM01231 1642 1780 1.5E-11 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 SUPERFAMILY SSF53474 3 271 3.16E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 4.9E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 4.9E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.9E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 Gene3D G3DSA:3.40.50.1820 2 273 4.9E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12780 da28a3b5ab6ce178129feed14c093f57 274 Pfam PF00561 alpha/beta hydrolase fold 23 254 1.4E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 Pfam PF00410 Ribosomal protein S8 5 131 4.7E-46 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 29.878 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 Gene3D G3DSA:3.30.1490.10 70 130 3.3E-20 T 28-03-2018 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 Gene3D G3DSA:3.30.1370.30 1 68 4.3E-23 T 28-03-2018 SmaCSM2_RS04060 3874eadcaaa55a52b4f5f4719af00193 132 SUPERFAMILY SSF56047 2 131 3.79E-43 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Pfam PF02824 TGS domain 2 61 5.8E-11 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 7.5E-217 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Gene3D G3DSA:3.10.20.30 1 64 5.3E-20 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 529 2.2E-41 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 5.8E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 5.8E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 5.8E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 5.8E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 5.8E-51 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 33.528 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Pfam PF03129 Anticodon binding domain 541 629 4.9E-20 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Gene3D G3DSA:3.40.50.800 532 631 2.2E-24 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 SUPERFAMILY SSF52954 530 630 2.11E-30 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 SUPERFAMILY SSF55186 63 240 6.93E-64 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 SMART SM00863 170 219 1.1E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 175 219 8.8E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Gene3D G3DSA:3.30.930.10 229 531 4.7E-119 T 28-03-2018 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 Gene3D G3DSA:3.30.980.10 69 228 7.0E-40 T 28-03-2018 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 SUPERFAMILY SSF55681 243 526 3.83E-96 T 28-03-2018 SmaCSM2_RS15035 065cd7f2f7c44c2d75e9c449c885dc94 633 SUPERFAMILY SSF81271 2 61 4.25E-15 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 Gene3D G3DSA:1.20.1600.10 35 483 1.0E-101 T 28-03-2018 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 477 6.9E-152 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 Pfam PF02321 Outer membrane efflux protein 298 475 1.9E-28 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 Pfam PF02321 Outer membrane efflux protein 76 266 7.5E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 SUPERFAMILY SSF56954 6 37 1.7E-109 T 28-03-2018 SmaCSM2_RS06755 87724bdbb94b0b62e77907d5b76427b3 497 SUPERFAMILY SSF56954 67 480 1.7E-109 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Gene3D G3DSA:1.10.238.10 97 122 6.2E-6 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Pfam PF13499 EF-hand domain pair 54 105 1.6E-7 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 SUPERFAMILY SSF47473 54 162 1.34E-17 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Pfam PF13202 EF hand 142 161 8.2E-6 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Pfam PF13202 EF hand 35 48 0.0021 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Gene3D G3DSA:1.10.238.10 46 68 4.1E-6 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 ProSitePatterns PS00018 EF-hand calcium-binding domain. 63 75 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Gene3D G3DSA:1.10.1330.10 69 96 1.3E-8 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Gene3D G3DSA:1.10.1330.10 30 45 0.055 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 Gene3D G3DSA:1.10.1330.10 123 165 1.0E-7 T 28-03-2018 SmaCSM2_RS05845 4f1ccae287cbc8e7404bce83054e22f8 186 ProSitePatterns PS00018 EF-hand calcium-binding domain. 148 160 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 PRINTS PR01021 OMPA domain signature 1934 1956 3.0E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 PRINTS PR01021 OMPA domain signature 1964 1979 3.0E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 PRINTS PR01021 OMPA domain signature 1979 1995 3.0E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:3.30.1330.60 1817 1902 4.1E-5 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Pfam PF00691 OmpA family 1933 2008 9.2E-8 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1454 1503 2.7E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 716 838 1.3E-8 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:3.30.1330.60 1903 2027 6.9E-17 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.1220 458 564 8.5E-12 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.10 1447 1573 2.2E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 1084 1201 5.0E-10 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 SUPERFAMILY SSF103088 1830 1894 7.19E-5 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 1325 1444 2.8E-5 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 839 958 1.2E-11 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 1202 1324 1.9E-11 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 590 715 4.1E-11 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 SUPERFAMILY SSF103088 1928 2000 1.23E-16 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Gene3D G3DSA:2.60.40.740 959 1083 1.2E-10 T 28-03-2018 SmaCSM2_RS09420 a108b004411690a920dcab3805b0d786 2027 Pfam PF01345 Domain of unknown function DUF11 1452 1547 7.8E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 SUPERFAMILY SSF51366 4 218 8.07E-74 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 5.1E-92 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 PIRSF PIRSF001461 1 224 7.5E-103 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 Gene3D G3DSA:3.20.20.70 1 221 2.8E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS19725 77b3b52fb386e3d90f065d3628d3a594 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 217 2.5E-96 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 Pfam PF12840 Helix-turn-helix domain 10 69 1.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 Gene3D G3DSA:1.10.10.10 1 99 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 3.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 SMART SM00418 8 88 2.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20155 55441e255a1b83cb6212affa1a2100be 104 SUPERFAMILY SSF46785 4 93 6.03E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 55.39 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 Gene3D G3DSA:3.20.20.105 1 371 4.5E-152 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 368 9.8E-150 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 369 1.9E-155 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 SUPERFAMILY SSF51713 3 368 7.46E-155 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS08825 977ca99023e3f34da80e2d558ff705ef 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 365 4.4E-87 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 Pfam PF00202 Aminotransferase class-III 39 461 8.0E-72 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 PIRSF PIRSF000521 33 144 0.027 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 PIRSF PIRSF000521 135 464 3.7E-27 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 Gene3D G3DSA:3.40.640.10 62 336 4.7E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 SUPERFAMILY SSF53383 29 463 2.89E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS06225 8e5bc2468e2933fc4019604582d8b376 466 Gene3D G3DSA:3.90.1150.10 337 466 1.7E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PIRSF PIRSF001369 38 425 5.8E-150 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 Gene3D G3DSA:1.10.230.10 283 380 1.1E-33 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 SUPERFAMILY SSF48256 8 423 7.72E-154 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 Pfam PF00285 Citrate synthase, C-terminal domain 47 412 2.1E-129 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 Gene3D G3DSA:1.10.580.10 30 282 5.1E-89 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 423 6.6E-183 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 360 376 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 220 235 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 242 270 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 297 317 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 380 394 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 PRINTS PR00143 Citrate synthase signature 166 179 4.1E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS17345 bd743883bbc7470786ee9e0917fa24a2 425 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SmaCSM2_RS16630 4f3900da9fea1400be9d2443b18ee09e 86 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 22 73 2.5E-10 T 28-03-2018 IPR031856 Putative bacterial antitoxin YdaS SmaCSM2_RS16630 4f3900da9fea1400be9d2443b18ee09e 86 Gene3D G3DSA:3.30.240.10 21 80 6.7E-4 T 28-03-2018 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Gene3D G3DSA:3.30.930.10 74 271 2.1E-49 T 28-03-2018 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 SUPERFAMILY SSF46785 6 55 7.74E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 SUPERFAMILY SSF50037 275 320 2.33E-8 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 2 320 30.58 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 85 319 5.6E-47 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Gene3D G3DSA:2.30.30.100 275 321 7.1E-15 T 28-03-2018 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Gene3D G3DSA:1.10.10.10 3 59 3.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 SUPERFAMILY SSF55681 82 271 1.54E-47 T 28-03-2018 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Pfam PF03099 Biotin/lipoate A/B protein ligase family 99 208 5.9E-9 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Pfam PF02237 Biotin protein ligase C terminal domain 276 320 4.8E-8 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SmaCSM2_RS01340 210d7b61fcddff0582f81acfad68a7ab 322 Pfam PF08279 HTH domain 5 53 2.4E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 301 1.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 451 2.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SUPERFAMILY SSF158472 182 232 1.1E-6 T 28-03-2018 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SMART SM00388 236 302 1.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 2.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 2.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 2.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 2.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 Gene3D G3DSA:3.30.565.10 306 455 1.8E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 Gene3D G3DSA:1.10.287.130 226 298 1.7E-9 T 28-03-2018 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SUPERFAMILY SSF55874 292 451 1.7E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 4 450 7.5E-121 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SMART SM00304 182 235 9.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SMART SM00387 345 453 3.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 SUPERFAMILY SSF47384 219 302 3.14E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11930 fc8836ec29fc93320ba5671719c5a64f 455 Pfam PF00672 HAMP domain 182 232 2.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 Gene3D G3DSA:2.40.50.140 1 69 1.7E-27 T 28-03-2018 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 6.5E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 28-03-2018 IPR019844 Cold-shock conserved site SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 SUPERFAMILY SSF50249 2 68 2.67E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 PRINTS PR00050 Cold shock protein signature 42 60 1.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 PRINTS PR00050 Cold shock protein signature 27 36 1.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 PRINTS PR00050 Cold shock protein signature 7 22 1.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 SMART SM00357 6 69 2.5E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SmaCSM2_RS14225 3aa1ba5f16dd5ce29fd450a60ce8de7b 69 PIRSF PIRSF002599 1 69 8.2E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Pfam PF14842 FliG N-terminal domain 1 101 7.3E-33 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Pfam PF01706 FliG C-terminal domain 215 320 4.2E-37 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 SUPERFAMILY SSF48029 3 117 4.45E-24 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 322 4.1E-100 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Gene3D G3DSA:1.10.220.30 191 328 8.4E-28 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Gene3D G3DSA:1.10.220.30 68 186 6.5E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PIRSF PIRSF003161 1 328 3.1E-114 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Gene3D G3DSA:1.10.220.30 2 65 2.8E-11 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 SUPERFAMILY SSF48029 110 321 1.23E-65 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 222 242 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 30 56 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 191 216 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 1 16 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 268 294 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 244 264 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 PRINTS PR00954 Flagellar motor switch protein FliG signature 110 133 2.2E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 SmaCSM2_RS10175 1af3a83e4851de4c572fd95d04a8f5b5 328 Pfam PF14841 FliG middle domain 111 184 2.9E-25 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 SUPERFAMILY SSF48179 164 269 5.78E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 SUPERFAMILY SSF51735 6 161 3.94E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 100 4.8E-16 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 Gene3D G3DSA:3.40.50.720 2 165 9.1E-27 T 28-03-2018 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 6.9E-83 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 26.145 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 Gene3D G3DSA:1.10.3730.10 166 273 1.1E-37 T 28-03-2018 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 1.1E-33 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 SmaCSM2_RS04965 2485b72451ff056b88d661493e5da62d 273 PIRSF PIRSF000193 3 271 1.4E-70 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Pfam PF00175 Oxidoreductase NAD-binding domain 377 476 8.7E-13 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Pfam PF00667 FAD binding domain 170 233 1.4E-10 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 SUPERFAMILY SSF63380 164 366 3.74E-38 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Gene3D G3DSA:1.20.990.10 169 243 9.8E-11 T 28-03-2018 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Pfam PF00258 Flavodoxin 16 142 1.9E-26 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 SUPERFAMILY SSF52343 364 509 7.2E-37 T 28-03-2018 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00369 Flavodoxin signature 90 100 1.3E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00369 Flavodoxin signature 60 71 1.3E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00369 Flavodoxin signature 14 27 1.3E-8 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 401 410 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 445 461 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 376 395 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 311 318 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 414 425 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 214 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 468 476 1.2E-19 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Gene3D G3DSA:2.40.30.10 265 371 3.4E-15 T 28-03-2018 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Gene3D G3DSA:3.40.50.80 372 507 3.0E-26 T 28-03-2018 SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 SUPERFAMILY SSF52218 12 151 3.03E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS12240 425aa3a50dd37f4f3c98830c00d8d72e 509 Gene3D G3DSA:3.40.50.360 6 166 1.6E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 281 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 Gene3D G3DSA:2.60.120.280 39 168 7.8E-5 T 28-03-2018 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 SMART SM00342 203 285 1.1E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 Gene3D G3DSA:1.10.10.60 242 292 4.6E-8 T 28-03-2018 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 SUPERFAMILY SSF46689 186 237 4.17E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 Gene3D G3DSA:1.10.10.60 181 241 3.4E-9 T 28-03-2018 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 Pfam PF12833 Helix-turn-helix domain 209 286 2.0E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 SUPERFAMILY SSF46689 239 285 2.73E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11855 29a0bbb867d55b2179ab20414ddd8d99 293 Pfam PF12852 Cupin 11 168 1.4E-28 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 SUPERFAMILY SSF50993 22 430 6.54E-85 T 28-03-2018 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 Gene3D G3DSA:3.40.50.1820 9 127 4.8E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 Gene3D G3DSA:3.40.50.1820 154 703 3.4E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 SUPERFAMILY SSF53474 436 696 4.14E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 Pfam PF00326 Prolyl oligopeptidase family 483 700 4.2E-67 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 26 426 1.8E-113 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 552 572 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 468 486 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 628 650 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 494 518 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 610 625 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18500 d252df82afd1d1aaaae1b81188f96622 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 522 541 2.2E-47 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18970 3b7b7ab3ca9d2aeca1ec69015e2e780d 186 Gene3D G3DSA:2.30.180.10 40 186 2.0E-37 T 28-03-2018 IPR000782 FAS1 domain SmaCSM2_RS18970 3b7b7ab3ca9d2aeca1ec69015e2e780d 186 Pfam PF02469 Fasciclin domain 51 185 7.9E-34 T 28-03-2018 IPR000782 FAS1 domain SmaCSM2_RS18970 3b7b7ab3ca9d2aeca1ec69015e2e780d 186 SMART SM00554 75 186 6.9E-25 T 28-03-2018 IPR000782 FAS1 domain SmaCSM2_RS18970 3b7b7ab3ca9d2aeca1ec69015e2e780d 186 SUPERFAMILY SSF82153 41 185 2.62E-40 T 28-03-2018 IPR000782 FAS1 domain SmaCSM2_RS06165 1f07b88ef813bb51d9b39530bdc0e7c9 122 Pfam PF05433 Glycine zipper 2TM domain 60 101 2.8E-10 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 SmaCSM2_RS03405 e184e3865baf05988c2343536e826b27 275 Gene3D G3DSA:3.40.50.150 14 260 7.1E-34 T 28-03-2018 SmaCSM2_RS03405 e184e3865baf05988c2343536e826b27 275 SUPERFAMILY SSF53335 28 229 1.26E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03405 e184e3865baf05988c2343536e826b27 275 Pfam PF08241 Methyltransferase domain 46 142 5.4E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS17540 08cf3d08d469c2bcd40321bf76ffb8fa 200 Pfam PF13419 Haloacid dehalogenase-like hydrolase 90 181 3.4E-8 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17540 08cf3d08d469c2bcd40321bf76ffb8fa 200 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 181 8.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS17540 08cf3d08d469c2bcd40321bf76ffb8fa 200 SUPERFAMILY SSF56784 5 190 3.61E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17540 08cf3d08d469c2bcd40321bf76ffb8fa 200 Gene3D G3DSA:3.40.50.1000 1 195 7.4E-22 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 30 787 2.1E-244 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 8 787 25.293 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 PIRSF PIRSF006076 2 787 1.8E-253 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Gene3D G3DSA:3.10.20.310 24 94 5.0E-11 T 28-03-2018 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Pfam PF01103 Surface antigen 454 787 7.4E-90 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Pfam PF07244 Surface antigen variable number repeat 99 178 7.6E-12 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Pfam PF07244 Surface antigen variable number repeat 272 350 6.1E-11 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Pfam PF07244 Surface antigen variable number repeat 354 426 2.9E-14 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Pfam PF07244 Surface antigen variable number repeat 182 269 8.2E-12 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Gene3D G3DSA:3.10.20.310 181 272 3.2E-15 T 28-03-2018 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Gene3D G3DSA:3.10.20.310 273 352 3.1E-15 T 28-03-2018 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Gene3D G3DSA:3.10.20.310 95 180 3.4E-16 T 28-03-2018 SmaCSM2_RS06605 5cafff6f8b804d184d1e8736e1ddbac7 787 Gene3D G3DSA:2.40.160.50 385 787 2.3E-93 T 28-03-2018 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 Gene3D G3DSA:3.40.1690.10 219 354 1.7E-54 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 9 354 1.8E-125 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 SUPERFAMILY SSF160544 245 352 3.66E-38 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 1.6E-37 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 1.6E-37 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 1.6E-37 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 1.6E-37 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 1.6E-37 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS10110 069e30c0219d9953ac80209d036a1026 376 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 348 2.1E-120 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 SmaCSM2_RS11225 ae88601eb585666888040610b6063f04 358 Pfam PF13533 Biotin-lipoyl like 62 107 2.8E-10 T 28-03-2018 SmaCSM2_RS11225 ae88601eb585666888040610b6063f04 358 SUPERFAMILY SSF111369 50 194 1.28E-14 T 28-03-2018 SmaCSM2_RS11225 ae88601eb585666888040610b6063f04 358 Gene3D G3DSA:2.40.50.100 59 132 3.8E-16 T 28-03-2018 SmaCSM2_RS11225 ae88601eb585666888040610b6063f04 358 Gene3D G3DSA:2.40.50.100 165 347 1.3E-5 T 28-03-2018 SmaCSM2_RS11225 ae88601eb585666888040610b6063f04 358 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 349 4.0E-43 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 96 1.0E-35 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 Gene3D G3DSA:3.30.300.20 5 115 1.4E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 SUPERFAMILY SSF89919 4 112 3.01E-27 T 28-03-2018 IPR023799 Ribosome-binding factor A domain SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 6 113 3.3E-24 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 116 19.095 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SmaCSM2_RS15080 bd699a4ee251889f1cc9389340922fdb 127 Pfam PF02033 Ribosome-binding factor A 7 109 8.7E-27 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Gene3D G3DSA:3.30.750.80 395 503 0.0031 T 28-03-2018 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 507 662 1.3E-16 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Pfam PF02926 THUMP domain 29 152 7.8E-11 T 28-03-2018 IPR004114 THUMP domain GO:0003723 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 198 209 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Pfam PF01170 Putative RNA methylase family UPF0020 161 372 2.8E-44 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 3 711 30.387 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 SMART SM00981 55 153 1.6E-20 T 28-03-2018 IPR004114 THUMP domain GO:0003723 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 PIRSF PIRSF037618 1 711 2.1E-277 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Gene3D G3DSA:3.40.50.150 92 354 6.8E-34 T 28-03-2018 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 SUPERFAMILY SSF53335 400 707 2.45E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 SUPERFAMILY SSF53335 262 375 1.76E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 SUPERFAMILY SSF53335 143 220 1.76E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 Gene3D G3DSA:3.40.50.150 504 711 3.2E-38 T 28-03-2018 SmaCSM2_RS06950 08fe0402eb0e5495ec6873f23e150561 712 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 308 314 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 Pfam PF00072 Response regulator receiver domain 22 130 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 Gene3D G3DSA:1.10.10.10 140 249 4.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 173 245 8.2E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 SMART SM00448 20 130 4.6E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 SUPERFAMILY SSF52172 20 141 1.02E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 SMART SM00862 171 245 2.5E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 SUPERFAMILY SSF46894 146 247 1.3E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS09730 ab9030e34375b75653da5e65c63821fc 249 Gene3D G3DSA:3.40.50.2300 12 139 7.6E-35 T 28-03-2018 SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 Gene3D G3DSA:3.40.630.40 274 502 1.6E-57 T 28-03-2018 SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 Pfam PF11741 AMIN domain 37 113 3.5E-12 T 28-03-2018 IPR021731 AMIN domain SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 SUPERFAMILY SSF53187 421 497 2.35E-53 T 28-03-2018 SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 SUPERFAMILY SSF53187 277 373 2.35E-53 T 28-03-2018 SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 279 494 6.0E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SmaCSM2_RS14760 477b3e4e4e9ecb5d49e7b9aa7adb6b1a 526 SMART SM00646 339 494 6.1E-65 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 Pfam PF01546 Peptidase family M20/M25/M40 63 371 1.7E-41 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 97 135 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 375 49.801 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 SUPERFAMILY SSF53187 292 373 1.65E-64 T 28-03-2018 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 SUPERFAMILY SSF53187 3 178 1.65E-64 T 28-03-2018 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 Gene3D G3DSA:3.40.630.10 269 373 0.0018 T 28-03-2018 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 Gene3D G3DSA:3.40.630.10 2 268 7.0E-64 T 28-03-2018 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 SUPERFAMILY SSF55031 179 287 6.13E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 373 2.6E-166 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 SmaCSM2_RS06710 349bbe310180b9647ab59f20faff7f62 378 Pfam PF07687 Peptidase dimerisation domain 175 282 1.1E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 160 231 2.9E-18 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 Gene3D G3DSA:3.20.70.20 139 765 1.1E-207 T 28-03-2018 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 Pfam PF02867 Ribonucleotide reductase, barrel domain 235 757 1.6E-182 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 163 761 1.6E-223 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 623 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 612 639 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 443 454 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 311 330 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 547 570 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 PRINTS PR01183 Ribonucleotide reductase large chain signature 519 541 1.2E-56 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 SUPERFAMILY SSF48168 31 233 5.75E-56 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 Pfam PF03477 ATP cone domain 26 111 4.9E-11 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 SUPERFAMILY SSF51998 692 762 3.36E-177 T 28-03-2018 SmaCSM2_RS01100 610225538d78893cc0e1e8d7438338bb 800 SUPERFAMILY SSF51998 234 661 3.36E-177 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:1.20.1640.10 901 1123 5.8E-43 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 PRINTS PR00702 Acriflavin resistance protein family signature 517 540 2.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 PRINTS PR00702 Acriflavin resistance protein family signature 492 515 2.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:3.30.70.1430 42 141 1.1E-22 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Pfam PF00873 AcrB/AcrD/AcrF family 619 1119 4.6E-118 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Pfam PF00873 AcrB/AcrD/AcrF family 278 542 1.8E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Pfam PF00873 AcrB/AcrD/AcrF family 6 260 1.9E-56 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:1.20.1640.10 334 554 5.3E-48 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82714 815 900 8.37E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82714 192 257 1.05E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82714 303 319 1.05E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:3.30.2090.10 814 900 8.0E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82866 344 544 4.58E-45 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82693 666 763 6.8E-6 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:3.30.2090.10 189 323 1.1E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82866 900 1122 3.53E-51 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 SUPERFAMILY SSF82693 43 134 7.85E-19 T 28-03-2018 SmaCSM2_RS08945 68383e61224458ce4cc6fd921a3cccab 1153 Gene3D G3DSA:3.30.70.1430 666 769 1.3E-11 T 28-03-2018 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PIRSF PIRSF036480 2 283 2.5E-111 T 28-03-2018 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 Gene3D G3DSA:3.40.50.170 87 283 1.1E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 7 33 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 88 110 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 137 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 4.7E-55 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 Pfam PF00551 Formyl transferase 88 263 5.8E-39 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 Pfam PF01842 ACT domain 6 56 5.8E-8 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 Gene3D G3DSA:3.30.70.260 2 86 1.8E-27 T 28-03-2018 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 SUPERFAMILY SSF55021 6 82 2.66E-19 T 28-03-2018 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 2 282 48.007 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 6 282 1.7E-101 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS01140 c1748ebb140b044bec303abdbf9179aa 283 SUPERFAMILY SSF53328 88 283 9.68E-60 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 494 3.0E-220 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 59.165 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 PIRSF PIRSF000538 3 497 2.3E-178 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 SUPERFAMILY SSF53067 5 255 1.57E-95 T 28-03-2018 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 3.5E-84 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 450 3.9E-62 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 SUPERFAMILY SSF53067 255 494 4.4E-82 T 28-03-2018 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 Gene3D G3DSA:3.30.420.40 249 498 4.3E-74 T 28-03-2018 SmaCSM2_RS18760 2960985d61307c172b750df6e76f8176 499 Gene3D G3DSA:3.30.420.40 1 248 4.0E-90 T 28-03-2018 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SUPERFAMILY SSF47384 136 207 3.73E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 315 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 329 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 350 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 369 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 371 8.4E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SMART SM00387 252 372 1.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Gene3D G3DSA:3.30.450.20 5 133 6.3E-25 T 28-03-2018 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SMART SM00388 144 211 5.1E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 209 3.2E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SUPERFAMILY SSF55874 201 371 7.73E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 128 1.7E-19 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SMART SM00091 7 73 0.0039 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Pfam PF13426 PAS domain 22 121 6.9E-11 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Gene3D G3DSA:3.30.565.10 212 378 2.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 Gene3D G3DSA:1.10.287.130 134 206 1.8E-6 T 28-03-2018 SmaCSM2_RS09435 71436f601fc4c9e14f98aae1bd0b7498 378 SUPERFAMILY SSF55785 20 131 1.39E-22 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11000 fd34ec8bf30f40e5e4e9c37e72352182 173 SUPERFAMILY SSF55961 25 168 4.85E-10 T 28-03-2018 SmaCSM2_RS11000 fd34ec8bf30f40e5e4e9c37e72352182 173 Gene3D G3DSA:3.30.530.20 24 173 7.1E-13 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 PRINTS PR00625 DnaJ domain signature 66 81 7.5E-11 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 PRINTS PR00625 DnaJ domain signature 88 108 7.5E-11 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 PRINTS PR00625 DnaJ domain signature 48 66 7.5E-11 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 Pfam PF00226 DnaJ domain 46 109 1.1E-12 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 SMART SM00271 45 108 3.2E-16 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 Gene3D G3DSA:1.10.287.110 27 109 9.8E-17 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS19730 bd597871f385fa9fc8acc9e96d0628d8 109 SUPERFAMILY SSF46565 38 109 3.01E-21 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS07845 f703e3d336f2488e66fe9990f34a225d 206 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 198 26.301 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 SmaCSM2_RS07845 f703e3d336f2488e66fe9990f34a225d 206 Gene3D G3DSA:3.40.50.360 2 203 1.5E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS07845 f703e3d336f2488e66fe9990f34a225d 206 SUPERFAMILY SSF52218 1 203 8.83E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS07845 f703e3d336f2488e66fe9990f34a225d 206 Pfam PF02525 Flavodoxin-like fold 3 195 5.3E-35 T 28-03-2018 IPR003680 Flavodoxin-like fold SmaCSM2_RS13520 050a30eeb149f7ddd196e5b8e15e7116 397 SUPERFAMILY SSF111369 51 237 2.75E-23 T 28-03-2018 SmaCSM2_RS13520 050a30eeb149f7ddd196e5b8e15e7116 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 266 5.9E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS13520 050a30eeb149f7ddd196e5b8e15e7116 397 Gene3D G3DSA:1.20.1600.10 60 351 3.7E-26 T 28-03-2018 SmaCSM2_RS13520 050a30eeb149f7ddd196e5b8e15e7116 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 272 1.6E-33 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 SUPERFAMILY SSF47917 349 465 9.94E-55 T 28-03-2018 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 464 3.7E-253 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Gene3D G3DSA:2.40.10.170 1 72 1.9E-27 T 28-03-2018 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Gene3D G3DSA:3.40.50.300 74 351 7.8E-92 T 28-03-2018 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 346 9.0E-62 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 464 56.379 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 70 6.6E-19 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 Gene3D G3DSA:1.10.1140.10 352 462 2.1E-44 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 SUPERFAMILY SSF52540 75 352 3.51E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 SUPERFAMILY SSF50615 1 71 4.45E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 SMART SM00382 140 323 0.0016 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18690 a854a5a61f99705701ec19b19ac83280 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 337 346 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS16075 691f4bb992791293c029e22a9c931516 455 PIRSF PIRSF006060 7 449 7.1E-70 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS16075 691f4bb992791293c029e22a9c931516 455 Pfam PF00324 Amino acid permease 22 419 1.8E-91 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SmaCSM2_RS16075 691f4bb992791293c029e22a9c931516 455 ProSitePatterns PS00218 Amino acid permeases signature. 46 76 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 Gene3D G3DSA:3.40.50.720 3 55 4.9E-11 T 28-03-2018 SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 Gene3D G3DSA:3.40.50.720 56 257 5.1E-64 T 28-03-2018 SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 SUPERFAMILY SSF51735 9 255 2.68E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19105 c0b3f4f38879d5e711ec5cef01ec166c 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 6.6E-63 T 28-03-2018 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 Pfam PF00155 Aminotransferase class I and II 102 445 2.8E-14 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 91 2.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 Gene3D G3DSA:3.40.640.10 128 370 4.9E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 SMART SM00345 32 91 9.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 Gene3D G3DSA:1.10.10.10 21 93 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 SUPERFAMILY SSF46785 25 93 3.71E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 Gene3D G3DSA:3.90.1150.10 371 463 2.8E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS20435 aecb1ba60e383789c2272ec7c14ba07b 471 SUPERFAMILY SSF53383 99 461 1.26E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Gene3D G3DSA:3.40.50.150 34 215 1.3E-30 T 28-03-2018 SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 SUPERFAMILY SSF53448 297 538 2.7E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 SUPERFAMILY SSF53756 695 859 3.2E-18 T 28-03-2018 SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Pfam PF13641 Glycosyltransferase like family 2 298 534 3.1E-11 T 28-03-2018 SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Pfam PF00534 Glycosyl transferases group 1 806 859 3.0E-7 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 SUPERFAMILY SSF53335 19 186 2.29E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Pfam PF05050 Methyltransferase FkbM domain 50 187 2.7E-15 T 28-03-2018 IPR006342 Methyltransferase FkbM SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Gene3D G3DSA:3.40.50.2000 737 931 6.1E-13 T 28-03-2018 SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 Gene3D G3DSA:3.90.550.10 275 586 9.3E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02700 880280a70fceab391c3b1538f5cf24cc 981 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 47 184 1.0E-27 T 28-03-2018 IPR006342 Methyltransferase FkbM SmaCSM2_RS14415 327f162e8a5eefcfeecd516b296f27b6 91 Pfam PF01722 BolA-like protein 13 89 8.1E-30 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS14415 327f162e8a5eefcfeecd516b296f27b6 91 PIRSF PIRSF003113 1 91 5.5E-28 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS14415 327f162e8a5eefcfeecd516b296f27b6 91 SUPERFAMILY SSF82657 4 89 1.22E-26 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS14415 327f162e8a5eefcfeecd516b296f27b6 91 Gene3D G3DSA:3.30.300.90 2 91 7.7E-27 T 28-03-2018 SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 Gene3D G3DSA:1.10.10.10 2 86 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 SUPERFAMILY SSF53850 91 292 4.52E-27 T 28-03-2018 SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 Pfam PF03466 LysR substrate binding domain 91 292 2.5E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 Gene3D G3DSA:3.40.190.10 91 182 5.4E-12 T 28-03-2018 SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.8E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 Gene3D G3DSA:3.40.190.10 183 267 8.4E-9 T 28-03-2018 SmaCSM2_RS08250 09f28ef75bbc7351ac68769816c106a4 306 SUPERFAMILY SSF46785 5 89 7.18E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07405 d8b1b3802bb7e76faa12649b9e496933 322 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 14 309 6.0E-79 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SmaCSM2_RS07405 d8b1b3802bb7e76faa12649b9e496933 322 SUPERFAMILY SSF54909 13 316 3.22E-95 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS07405 d8b1b3802bb7e76faa12649b9e496933 322 Pfam PF04261 Dyp-type peroxidase family 14 309 1.2E-86 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 SMART SM00388 231 289 0.0013 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 SUPERFAMILY SSF47384 216 285 1.67E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 SMART SM00387 329 437 1.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 Gene3D G3DSA:3.30.565.10 305 437 2.4E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 SUPERFAMILY SSF55874 297 436 5.24E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 436 7.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 Gene3D G3DSA:1.10.287.130 214 287 2.7E-5 T 28-03-2018 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 SMART SM00304 178 230 3.3E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 1.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 1.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS05640 3720bfc9f82a30001a033f1f8e9bbd81 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 1.3E-51 T 28-03-2018 SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 Gene3D G3DSA:3.40.50.720 2 245 5.7E-63 T 28-03-2018 SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 SUPERFAMILY SSF51735 7 244 4.59E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18260 45580f12a67196a9338a58676c12ddb8 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS03150 11f2f837fe4cc1c3e28636c417d7ec6c 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 150 1.4E-42 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03150 11f2f837fe4cc1c3e28636c417d7ec6c 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 151 2.5E-51 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03150 11f2f837fe4cc1c3e28636c417d7ec6c 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 28.287 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03150 11f2f837fe4cc1c3e28636c417d7ec6c 155 SUPERFAMILY SSF52121 7 154 1.96E-52 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03150 11f2f837fe4cc1c3e28636c417d7ec6c 155 Gene3D G3DSA:3.40.50.960 1 155 9.8E-57 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS01995 fa391b9d6da7680e8e476ad833142446 186 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 84 167 1.7E-16 T 28-03-2018 IPR003744 Queuosine precursor transporter SmaCSM2_RS01995 fa391b9d6da7680e8e476ad833142446 186 Pfam PF02592 Putative vitamin uptake transporter 85 173 1.1E-18 T 28-03-2018 IPR003744 Queuosine precursor transporter SmaCSM2_RS01995 fa391b9d6da7680e8e476ad833142446 186 Pfam PF02592 Putative vitamin uptake transporter 44 86 4.4E-8 T 28-03-2018 IPR003744 Queuosine precursor transporter SmaCSM2_RS12570 a59f4f279064c1a0e77accda6451eb5a 717 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 156 4.1E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12570 a59f4f279064c1a0e77accda6451eb5a 717 Gene3D G3DSA:2.170.130.10 24 161 1.3E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12570 a59f4f279064c1a0e77accda6451eb5a 717 SUPERFAMILY SSF56935 23 717 6.23E-91 T 28-03-2018 SmaCSM2_RS12570 a59f4f279064c1a0e77accda6451eb5a 717 Gene3D G3DSA:2.40.170.20 181 717 3.2E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12570 a59f4f279064c1a0e77accda6451eb5a 717 Pfam PF00593 TonB dependent receptor 244 715 3.1E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10805 650796f3caf35e26013742e7744f7391 399 Pfam PF02321 Outer membrane efflux protein 4 188 3.8E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS10805 650796f3caf35e26013742e7744f7391 399 Pfam PF02321 Outer membrane efflux protein 212 392 1.3E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS10805 650796f3caf35e26013742e7744f7391 399 SUPERFAMILY SSF56954 2 392 4.71E-48 T 28-03-2018 SmaCSM2_RS10805 650796f3caf35e26013742e7744f7391 399 Gene3D G3DSA:1.20.1600.10 1 392 2.4E-42 T 28-03-2018 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 SUPERFAMILY SSF46689 439 491 1.39E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 SUPERFAMILY SSF46689 350 393 1.39E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Pfam PF00158 Sigma-54 interaction domain 140 304 2.2E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Gene3D G3DSA:1.10.10.60 379 496 2.2E-17 T 28-03-2018 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Gene3D G3DSA:1.10.8.60 311 378 3.0E-22 T 28-03-2018 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 SUPERFAMILY SSF52540 140 379 1.2E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 472 492 6.1E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 455 472 6.1E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 SMART SM00382 158 302 6.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Pfam PF02954 Bacterial regulatory protein, Fis family 450 489 1.6E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Gene3D G3DSA:3.40.50.300 133 310 2.0E-25 T 28-03-2018 SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 Pfam PF06490 Flagellar regulatory protein FleQ 5 120 9.8E-20 T 28-03-2018 IPR010518 Flagellar regulatory FleQ SmaCSM2_RS10195 b4ca1a447f2d4c20101975f7bc783227 500 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 SmaCSM2_RS10740 06f6fd08e009e295b8d8c587092b9d4e 78 ProDom PD007968 PLASMID MERE URF-1 RESISTANCE MERCURY MERCURIC DELTA URF1 PRECURSOR TNIB 18 54 1.0E-14 T 28-03-2018 IPR007746 MerE GO:0015097|GO:0015694|GO:0016020 SmaCSM2_RS10740 06f6fd08e009e295b8d8c587092b9d4e 78 Pfam PF05052 MerE protein 1 74 9.3E-47 T 28-03-2018 IPR007746 MerE GO:0015097|GO:0015694|GO:0016020 SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 PIRSF PIRSF002122 2 157 1.8E-61 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 Gene3D G3DSA:1.10.455.10 6 157 3.4E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 6.6E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 157 6.3E-65 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 SUPERFAMILY SSF47973 1 150 3.4E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SmaCSM2_RS03970 e13864065224b2425c264885e9b244ec 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 35.435 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 SUPERFAMILY SSF51338 3 57 4.99E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 SUPERFAMILY SSF51338 351 377 4.99E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 SUPERFAMILY SSF51556 57 351 4.08E-100 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 Gene3D G3DSA:2.30.40.10 1 71 1.0E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 Pfam PF01979 Amidohydrolase family 54 378 9.4E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 Gene3D G3DSA:3.20.20.140 72 351 2.9E-92 T 28-03-2018 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 PIRSF PIRSF038994 1 381 9.1E-114 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SmaCSM2_RS18215 1536d603774797ae1aa8e19bd8117c2a 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 377 3.6E-99 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 Gene3D G3DSA:1.10.287.470 116 158 1.6E-9 T 28-03-2018 SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 Gene3D G3DSA:2.40.50.100 159 368 3.4E-5 T 28-03-2018 SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 288 2.5E-14 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 366 1.4E-83 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 Gene3D G3DSA:2.40.50.100 58 115 1.8E-16 T 28-03-2018 SmaCSM2_RS13995 26c3ee25250760651000f2db11c5915d 422 SUPERFAMILY SSF111369 47 292 4.97E-71 T 28-03-2018 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 Pfam PF00771 FHIPEP family 32 692 3.6E-260 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 3.4E-51 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 24 701 8.1E-255 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 SmaCSM2_RS10105 e22e0b60ac871d9acb8f4e793937ea34 702 PIRSF PIRSF005419 9 702 1.4E-238 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 485 607 1.6E-49 T 28-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 Gene3D G3DSA:2.40.10.200 503 607 2.1E-40 T 28-03-2018 SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 Gene3D G3DSA:1.10.3210.10 59 225 9.2E-7 T 28-03-2018 SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 26 243 5.8E-89 T 28-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 SUPERFAMILY SSF46785 484 608 1.74E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07510 409d50699c52ae84cdc7e2c3d7b24d3b 612 Pfam PF07514 Putative helicase 27 339 8.6E-129 T 28-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Gene3D G3DSA:1.10.3500.10 363 507 9.7E-39 T 28-03-2018 IPR023323 Tex-like domain SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SUPERFAMILY SSF50249 647 730 1.27E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SMART SM00732 334 433 2.3E-39 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Pfam PF09371 Tex-like protein N-terminal domain 19 202 8.4E-65 T 28-03-2018 IPR018974 Tex-like protein, N-terminal SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Pfam PF12836 Helix-hairpin-helix motif 500 564 1.4E-27 T 28-03-2018 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SUPERFAMILY SSF47781 479 566 1.45E-26 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Pfam PF16921 Tex protein YqgF-like domain 334 460 7.1E-55 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SMART SM00316 658 729 5.6E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Gene3D G3DSA:1.10.150.310 508 639 7.6E-41 T 28-03-2018 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SUPERFAMILY SSF47781 569 641 1.62E-18 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Pfam PF00575 S1 RNA binding domain 658 729 8.8E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Gene3D G3DSA:1.10.3500.10 113 362 3.7E-72 T 28-03-2018 IPR023323 Tex-like domain SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Gene3D G3DSA:2.40.50.140 661 757 3.3E-24 T 28-03-2018 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SUPERFAMILY SSF53098 330 478 1.97E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 Gene3D G3DSA:1.10.10.650 12 112 8.1E-32 T 28-03-2018 IPR023319 Tex-like protein, HTH domain SmaCSM2_RS13220 cb49faac333b4344b4ba1667aa45ff05 795 SUPERFAMILY SSF158832 12 329 1.23E-111 T 28-03-2018 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 Gene3D G3DSA:3.30.565.10 184 357 2.9E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 3.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 3.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 356 3.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 3.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 201 6.2E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 Pfam PF00672 HAMP domain 83 134 3.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SUPERFAMILY SSF55874 192 357 7.2E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 Gene3D G3DSA:1.10.287.130 128 183 1.2E-10 T 28-03-2018 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 357 9.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SUPERFAMILY SSF158472 84 135 7.98E-7 T 28-03-2018 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SMART SM00388 138 202 1.5E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SUPERFAMILY SSF47384 121 200 2.55E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SMART SM00304 83 137 1.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS09725 ff6330f3eb88c5967a289fbed2ac45cd 358 SMART SM00387 248 358 5.9E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 SUPERFAMILY SSF53067 151 348 2.43E-25 T 28-03-2018 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 SUPERFAMILY SSF53067 74 119 2.43E-25 T 28-03-2018 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 SUPERFAMILY SSF53067 11 44 2.43E-25 T 28-03-2018 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 11 373 1.9E-144 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 Gene3D G3DSA:3.30.420.40 243 375 7.2E-26 T 28-03-2018 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 Gene3D G3DSA:3.30.420.40 9 190 9.2E-56 T 28-03-2018 SmaCSM2_RS01685 04ca97690e492c3d6bd38119e973687c 375 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 10 375 41.324 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SmaCSM2_RS02210 d4780ef61bce449df9525c5ef4b54488 392 SUPERFAMILY SSF56601 21 385 1.24E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS02210 d4780ef61bce449df9525c5ef4b54488 392 Pfam PF00144 Beta-lactamase 27 380 3.1E-61 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS02210 d4780ef61bce449df9525c5ef4b54488 392 Gene3D G3DSA:3.40.710.10 8 387 2.3E-78 T 28-03-2018 SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 SUPERFAMILY SSF53223 806 992 6.23E-20 T 28-03-2018 SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 Gene3D G3DSA:3.40.50.720 989 1327 1.4E-53 T 28-03-2018 SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 SUPERFAMILY SSF51735 1136 1268 5.05E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 SUPERFAMILY SSF51735 996 1098 5.05E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 Gene3D G3DSA:3.40.50.150 1512 1613 0.0033 T 28-03-2018 SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 Pfam PF12466 Glutamate dehydrogenase N terminal 5 90 8.4E-35 T 28-03-2018 IPR024727 Bacterial NAD-glutamate dehydrogenase, N-terminal SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 94 1651 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 SmaCSM2_RS13985 df012d9a26cd87c3840486b45def76dc 1658 PIRSF PIRSF036761 25 1658 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 Gene3D G3DSA:3.90.180.10 1 143 6.9E-34 T 28-03-2018 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 Pfam PF00107 Zinc-binding dehydrogenase 170 292 3.9E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 54 68 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 128 1.5E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 SUPERFAMILY SSF50129 5 156 1.4E-35 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 SUPERFAMILY SSF51735 135 292 2.8E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 Gene3D G3DSA:3.40.50.720 144 321 2.1E-29 T 28-03-2018 SmaCSM2_RS19975 5cd77763a2a36524f7bcf15b58aaf3f4 341 SMART SM00829 7 328 1.2E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 SUPERFAMILY SSF46934 2 55 1.22E-17 T 28-03-2018 IPR009060 UBA-like GO:0005515 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 Gene3D G3DSA:3.30.479.20 57 155 1.9E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 Hamap MF_00050 Elongation factor Ts [tsf]. 1 289 69.8 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 Gene3D G3DSA:1.10.8.10 1 55 1.1E-22 T 28-03-2018 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 290 1.8E-92 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 Gene3D G3DSA:3.30.479.20 156 288 3.8E-34 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 Pfam PF00889 Elongation factor TS 70 272 2.2E-59 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 SUPERFAMILY SSF54713 149 290 4.06E-38 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS06645 9eef96b9e8031f7564a1443f14c2f289 291 SUPERFAMILY SSF54713 55 144 1.63E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS05360 dfb4b3aa9322a267d2dcf8d3bb3263f1 143 Gene3D G3DSA:3.30.300.20 3 143 2.6E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS05360 dfb4b3aa9322a267d2dcf8d3bb3263f1 143 SUPERFAMILY SSF82784 2 133 1.24E-36 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS05360 dfb4b3aa9322a267d2dcf8d3bb3263f1 143 Pfam PF02566 OsmC-like protein 42 138 6.9E-21 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS05360 dfb4b3aa9322a267d2dcf8d3bb3263f1 143 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 140 2.9E-58 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 SUPERFAMILY SSF53822 59 312 9.23E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 Pfam PF13377 Periplasmic binding protein-like domain 167 324 3.6E-34 T 28-03-2018 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 2.6E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 Gene3D G3DSA:3.40.50.2300 56 165 2.0E-31 T 28-03-2018 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 Gene3D G3DSA:1.10.260.40 1 55 1.1E-19 T 28-03-2018 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 SMART SM00354 2 71 9.3E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 Gene3D G3DSA:3.40.50.2300 166 327 2.2E-42 T 28-03-2018 SmaCSM2_RS11260 60b90efb4e63e13c8c858b704705446c 337 SUPERFAMILY SSF47413 4 56 1.31E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 Pfam PF00005 ABC transporter 21 169 6.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 SMART SM00930 260 333 3.2E-25 T 28-03-2018 IPR018449 NIL domain SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 SMART SM00382 30 217 9.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 Pfam PF09383 NIL domain 262 332 2.2E-19 T 28-03-2018 IPR018449 NIL domain SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 Gene3D G3DSA:3.40.50.300 1 252 1.1E-79 T 28-03-2018 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 SUPERFAMILY SSF55021 260 333 8.36E-17 T 28-03-2018 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 Gene3D G3DSA:3.30.70.260 253 335 7.6E-21 T 28-03-2018 SmaCSM2_RS18540 d924096a855365afeac167808d6d394e 335 SUPERFAMILY SSF52540 1 240 2.32E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Pfam PF14579 Helix-hairpin-helix motif 826 915 2.8E-25 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Gene3D G3DSA:1.10.150.280 806 912 1.1E-8 T 28-03-2018 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 304 752 1.2E-168 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1059 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Gene3D G3DSA:2.40.50.140 1021 1100 4.0E-8 T 28-03-2018 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Pfam PF01336 OB-fold nucleic acid binding domain 1028 1093 3.2E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 SUPERFAMILY SSF89550 6 249 9.61E-11 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 SMART SM00481 7 88 3.8E-13 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Pfam PF02811 PHP domain 8 183 1.5E-23 T 28-03-2018 IPR004013 PHP domain GO:0003824 SmaCSM2_RS06575 7406fd703afde8a62058314c27a704c1 1196 Gene3D G3DSA:3.20.20.140 5 267 1.0E-31 T 28-03-2018 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 PRINTS PR00061 Ribosomal protein L19 signature 38 67 4.3E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 PRINTS PR00061 Ribosomal protein L19 signature 92 117 4.3E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 PRINTS PR00061 Ribosomal protein L19 signature 8 37 4.3E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 SUPERFAMILY SSF50104 8 121 9.43E-42 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 7 117 4.0E-44 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 PIRSF PIRSF002191 1 133 3.1E-47 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 Pfam PF01245 Ribosomal protein L19 8 116 1.7E-45 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06080 9f766ffa02c6aed676823a46833565fb 133 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 6 118 28.219 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 Gene3D G3DSA:3.30.2350.10 66 238 7.8E-31 T 28-03-2018 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 105 119 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 SMART SM00363 3 65 1.4E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 Pfam PF01479 S4 domain 4 48 1.5E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 SUPERFAMILY SSF55174 4 56 1.85E-11 T 28-03-2018 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 Pfam PF00849 RNA pseudouridylate synthase 70 149 1.2E-13 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 74 227 2.7E-46 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 SUPERFAMILY SSF55120 69 230 1.01E-36 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS06455 ba744e1f68432cd9aa11ae10540a1414 240 Gene3D G3DSA:3.10.290.10 1 59 3.3E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 546 790 2.6E-98 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Pfam PF04679 ATP dependent DNA ligase C terminal region 433 526 1.0E-21 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Gene3D G3DSA:3.30.1490.70 361 402 1.0E-9 T 28-03-2018 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Pfam PF13298 DNA polymerase Ligase (LigD) 40 144 6.3E-35 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 3 162 2.3E-64 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Gene3D G3DSA:2.40.50.140 403 528 8.5E-33 T 28-03-2018 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 SUPERFAMILY SSF50249 415 530 2.44E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 232 531 1.9E-97 T 28-03-2018 IPR014146 DNA ligase D, ligase domain SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 242 819 1.0E-184 T 28-03-2018 IPR014143 DNA ligase D SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Gene3D G3DSA:3.30.470.30 196 360 4.9E-34 T 28-03-2018 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 SUPERFAMILY SSF56091 210 413 9.59E-44 T 28-03-2018 SmaCSM2_RS00220 bbdcade180548ab42db6dc9784717858 830 Pfam PF01068 ATP dependent DNA ligase domain 245 412 1.8E-23 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Gene3D G3DSA:1.10.540.10 1 125 4.2E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 1.8E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 SUPERFAMILY SSF47203 233 385 5.64E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Gene3D G3DSA:2.40.110.10 126 223 6.4E-42 T 28-03-2018 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.6E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 SUPERFAMILY SSF56645 5 247 1.57E-84 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Gene3D G3DSA:1.20.140.10 224 386 5.7E-55 T 28-03-2018 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 PIRSF PIRSF016578 13 113 0.74 T 28-03-2018 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 PIRSF PIRSF016578 135 386 5.0E-11 T 28-03-2018 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 122 2.5E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS01045 f6742c1db3beedeada86a6318e553dd8 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Gene3D G3DSA:3.40.50.300 292 581 2.7E-53 T 28-03-2018 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SMART SM00382 333 518 6.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Hamap MF_01884 Transcription termination factor Rho [rho]. 163 581 227.944 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SUPERFAMILY SSF52540 253 534 1.41E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SUPERFAMILY SSF50249 213 287 9.71E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Pfam PF07497 Rho termination factor, RNA-binding domain 215 288 2.2E-28 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SMART SM00357 215 281 8.1E-17 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Gene3D G3DSA:2.40.50.140 212 279 7.2E-27 T 28-03-2018 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 323 526 6.2E-23 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 TIGRFAM TIGR00767 rho: transcription termination factor Rho 164 580 2.5E-204 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Gene3D G3DSA:1.10.720.10 167 205 8.4E-11 T 28-03-2018 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SMART SM00959 167 210 3.3E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 SUPERFAMILY SSF68912 164 209 4.32E-7 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SmaCSM2_RS19460 a737edccb59586c0c12f1dd531619ce9 581 Pfam PF07498 Rho termination factor, N-terminal domain 167 209 7.6E-13 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 Gene3D G3DSA:2.60.40.1180 182 282 4.0E-17 T 28-03-2018 SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 SUPERFAMILY SSF81901 194 271 2.09E-17 T 28-03-2018 SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 SUPERFAMILY SSF81901 118 159 2.09E-17 T 28-03-2018 SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 SMART SM00671 199 234 2.2E-7 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 SMART SM00671 235 271 0.51 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 Pfam PF08238 Sel1 repeat 237 268 0.039 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 Pfam PF08238 Sel1 repeat 200 234 9.3E-7 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 Pfam PF08238 Sel1 repeat 62 75 1.0 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS06715 4c8dc67f49be032f83d1c66b4094aada 292 Gene3D G3DSA:1.25.40.10 8 168 5.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 Pfam PF00857 Isochorismatase family 32 205 7.9E-38 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 Gene3D G3DSA:3.40.50.850 1 210 1.4E-49 T 28-03-2018 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 112 134 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 2 14 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 80 99 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 168 186 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 63 80 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 PRINTS PR01398 Isochorismatase signature 186 203 6.3E-35 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SmaCSM2_RS12500 61346c614d1d2b3b66138c9ecadeeee5 210 SUPERFAMILY SSF52499 1 210 5.1E-61 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 SUPERFAMILY SSF52794 112 210 7.85E-36 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 Gene3D G3DSA:3.40.50.2300 112 210 2.5E-38 T 28-03-2018 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 114 197 1.1E-36 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 Gene3D G3DSA:3.40.50.2300 4 100 3.4E-15 T 28-03-2018 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 224 560 6.6E-139 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 SUPERFAMILY SSF52794 6 95 2.07E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SmaCSM2_RS11275 4e4e307c8e0de49ba3eecb29c9eb9db8 568 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 115 204 1.6E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SmaCSM2_RS19580 081b4ab4a14c72f6a6cd292fc625fc34 141 Pfam PF10825 Protein of unknown function (DUF2752) 45 92 1.3E-18 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 Gene3D G3DSA:1.10.10.10 3 87 4.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 Pfam PF03466 LysR substrate binding domain 88 293 2.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 Gene3D G3DSA:3.40.190.10 92 175 3.1E-8 T 28-03-2018 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 Gene3D G3DSA:3.40.190.10 176 265 3.9E-28 T 28-03-2018 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 SUPERFAMILY SSF53850 89 296 6.33E-42 T 28-03-2018 SmaCSM2_RS17790 989b5aac26b7c2c618c6eb5c198cc44b 301 SUPERFAMILY SSF46785 4 86 4.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:2.60.40.1180 567 627 4.0E-16 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Pfam PF00754 F5/8 type C domain 809 921 6.6E-9 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SUPERFAMILY SSF49785 803 920 3.69E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SUPERFAMILY SSF51011 532 620 5.11E-13 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:2.60.40.1180 628 773 8.2E-32 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SMART SM00776 970 1108 3.0E-10 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SUPERFAMILY SSF74650 49 245 6.91E-22 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:3.20.20.80 246 370 2.7E-13 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:3.20.20.80 377 566 8.6E-49 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SUPERFAMILY SSF51445 250 530 5.62E-28 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:2.60.120.260 797 934 2.7E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Pfam PF08305 NPCBM/NEW2 domain 973 1106 2.4E-24 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Gene3D G3DSA:2.60.40.1760 38 245 1.0E-30 T 28-03-2018 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Pfam PF17137 Domain of unknown function (DUF5110) 642 713 1.2E-16 T 28-03-2018 IPR033403 Domain of unknown function DUF5110 SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 SUPERFAMILY SSF49785 974 1107 2.38E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS20580 8e4b3d53bb54bb05e4d2fcff216c43f1 1119 Pfam PF01055 Glycosyl hydrolases family 31 390 625 6.3E-52 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1157 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:1.10.287.620 251 410 6.0E-7 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:1.20.5.170 411 509 0.056 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1159 23.162 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:1.20.5.50 655 700 0.088 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 SUPERFAMILY SSF57997 660 891 3.27E-5 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 SUPERFAMILY SSF75553 483 668 6.8E-8 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:1.20.5.730 701 776 2.5E-6 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 SUPERFAMILY SSF52540 959 1159 6.23E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 SUPERFAMILY SSF52540 1 210 6.23E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:3.40.50.300 777 1166 2.4E-23 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Gene3D G3DSA:3.40.50.300 1 250 1.2E-39 T 28-03-2018 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1150 4.5E-68 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 SMART SM00968 521 619 0.0018 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SmaCSM2_RS13885 3a71a5871c1a84dd5f344afe984f6172 1167 PIRSF PIRSF005719 1 1165 5.5E-268 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein SmaCSM2_RS17750 13918e1d561965b3009045f53af4bf81 83 SUPERFAMILY SSF55021 1 74 1.04E-5 T 28-03-2018 SmaCSM2_RS17750 13918e1d561965b3009045f53af4bf81 83 Pfam PF13710 ACT domain 12 73 1.2E-19 T 28-03-2018 SmaCSM2_RS17750 13918e1d561965b3009045f53af4bf81 83 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 73 9.0E-5 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF56784 419 668 2.92E-52 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF56784 360 380 2.92E-52 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 Pfam PF00122 E1-E2 ATPase 160 341 1.5E-53 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 68 670 9.0E-174 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 Gene3D G3DSA:1.20.1110.10 124 377 1.8E-45 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF81653 167 260 9.42E-26 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 Pfam PF00702 haloacid dehalogenase-like hydrolase 358 575 6.2E-39 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 131 654 2.7E-86 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 87 670 1.5E-182 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 129 148 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 72 91 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 149 167 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 283 297 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 345 360 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00943 Copper-transporting ATPase signature 538 555 2.1E-15 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF81665 128 163 1.57E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF81665 261 356 1.57E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 SUPERFAMILY SSF81665 610 633 1.57E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 364 370 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 Gene3D G3DSA:3.40.1110.10 378 488 2.3E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 596 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 518 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 580 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 486 497 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 210 224 3.1E-26 T 28-03-2018 SmaCSM2_RS10845 19b93d49eeaa4d884813e8dfedffad67 694 Gene3D G3DSA:3.40.50.1000 489 626 4.3E-37 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 Gene3D G3DSA:3.40.50.1000 76 218 5.4E-37 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 Gene3D G3DSA:3.40.50.1000 3 32 0.25 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 188 2.0E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 215 1.6E-59 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 SUPERFAMILY SSF56784 4 216 1.97E-55 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 Gene3D G3DSA:1.10.150.240 33 75 1.9E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS02510 68b9bb59cf0bea219c0af745af035c35 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 182 1.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS06495 d649eea942b8657462820771c7700e11 403 Gene3D G3DSA:3.40.50.1240 18 403 1.6E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS06495 d649eea942b8657462820771c7700e11 403 ProSitePatterns PS00778 Histidine acid phosphatases active site signature. 298 314 - T 28-03-2018 IPR033379 Histidine acid phosphatase active site SmaCSM2_RS06495 d649eea942b8657462820771c7700e11 403 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 27 41 - T 28-03-2018 IPR033379 Histidine acid phosphatase active site SmaCSM2_RS06495 d649eea942b8657462820771c7700e11 403 SUPERFAMILY SSF53254 21 400 7.79E-60 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 SUPERFAMILY SSF54534 292 392 2.03E-26 T 28-03-2018 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Pfam PF00639 PPIC-type PPIASE domain 298 389 1.8E-24 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Pfam PF00639 PPIC-type PPIASE domain 182 276 2.5E-17 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Gene3D G3DSA:3.10.50.40 286 415 9.5E-29 T 28-03-2018 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Gene3D G3DSA:3.10.50.40 171 285 2.8E-23 T 28-03-2018 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 SUPERFAMILY SSF109998 32 204 3.85E-41 T 28-03-2018 IPR027304 Trigger factor/SurA domain SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 SUPERFAMILY SSF54534 169 277 2.49E-26 T 28-03-2018 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Pfam PF09312 SurA N-terminal domain 32 149 2.6E-42 T 28-03-2018 IPR015391 SurA N-terminal SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Gene3D G3DSA:1.10.4030.10 28 155 8.7E-23 T 28-03-2018 SmaCSM2_RS03565 5e82e3f2777646715477fd49e8618aa3 448 Hamap MF_01183 Chaperone SurA [surA]. 8 436 31.224 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 286 2.1E-99 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 Gene3D G3DSA:3.10.450.50 164 295 1.1E-19 T 28-03-2018 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 Gene3D G3DSA:1.10.10.10 101 163 1.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 Gene3D G3DSA:1.10.1740.10 2 74 1.4E-15 T 28-03-2018 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 Pfam PF08281 Sigma-70, region 4 110 161 1.2E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 162 4.2E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 SUPERFAMILY SSF88946 4 67 6.67E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 SUPERFAMILY SSF88659 103 162 1.29E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 SUPERFAMILY SSF54427 173 285 5.27E-14 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS14260 73244c9e9dd99ebc44880e5719bb53cc 298 Pfam PF04542 Sigma-70 region 2 7 71 1.5E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 Gene3D G3DSA:3.40.50.150 9 190 7.7E-20 T 28-03-2018 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 7.2E-9 T 28-03-2018 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 130 154 7.2E-9 T 28-03-2018 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 101 113 7.2E-9 T 28-03-2018 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 104 110 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS07670 7a342255ca7138024d9a4e0a58f6c5b0 369 SUPERFAMILY SSF53335 18 187 2.74E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Pfam PF00817 impB/mucB/samB family 10 156 8.8E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Pfam PF11798 IMS family HHH motif 168 199 3.9E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Gene3D G3DSA:3.30.70.270 117 171 3.5E-22 T 28-03-2018 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Gene3D G3DSA:3.30.70.270 43 116 4.6E-25 T 28-03-2018 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Pfam PF11799 impB/mucB/samB family C-terminal domain 235 346 3.0E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Gene3D G3DSA:1.10.150.20 172 247 1.3E-21 T 28-03-2018 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Gene3D G3DSA:3.30.1490.100 248 345 5.3E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 SUPERFAMILY SSF56672 4 236 1.07E-92 T 28-03-2018 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 Hamap MF_01113 DNA polymerase IV [dinB]. 4 353 37.201 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SmaCSM2_RS02480 5dab9f036fac7fbe889c3a588647a05d 364 SUPERFAMILY SSF100879 241 340 2.35E-19 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 Gene3D G3DSA:3.20.20.70 115 278 0.0089 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 333 5.0E-108 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 28 320 6.6E-71 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 7 337 38.23 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 SUPERFAMILY SSF52540 52 182 6.11E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07320 5c55d349baab7dba089efdc60c44b5e3 339 Gene3D G3DSA:3.20.20.70 25 108 0.0093 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS01490 9031513dc480fe56475442e2cc399dd4 367 Gene3D G3DSA:2.40.180.10 46 358 5.0E-68 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS01490 9031513dc480fe56475442e2cc399dd4 367 SUPERFAMILY SSF56634 39 350 4.19E-85 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS01490 9031513dc480fe56475442e2cc399dd4 367 SMART SM01060 43 363 8.3E-5 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS01490 9031513dc480fe56475442e2cc399dd4 367 PIRSF PIRSF000296 20 354 3.0E-114 T 28-03-2018 IPR024168 Catalase, SrpA-type, predicted SmaCSM2_RS01490 9031513dc480fe56475442e2cc399dd4 367 Pfam PF00199 Catalase 70 348 2.1E-22 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS05270 a7a6fc6390a8d93af1984d842a9536af 225 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 175 1.4E-14 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SmaCSM2_RS05270 a7a6fc6390a8d93af1984d842a9536af 225 Gene3D G3DSA:2.60.120.620 2 185 5.0E-35 T 28-03-2018 SmaCSM2_RS05270 a7a6fc6390a8d93af1984d842a9536af 225 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 225 46.685 T 28-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 SmaCSM2_RS05270 a7a6fc6390a8d93af1984d842a9536af 225 SMART SM00702 1 176 2.4E-30 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 SmaCSM2_RS05270 a7a6fc6390a8d93af1984d842a9536af 225 SUPERFAMILY SSF51197 3 177 6.32E-6 T 28-03-2018 SmaCSM2_RS21740 5a64e4167f17f3e5b291955b1ffa59fd 360 Pfam PF14350 Beta protein 2 348 6.3E-80 T 28-03-2018 IPR025683 Protein beta SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Gene3D G3DSA:1.10.540.10 1 123 1.1E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Gene3D G3DSA:2.40.110.10 124 220 5.7E-38 T 28-03-2018 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 SUPERFAMILY SSF56645 6 244 6.54E-77 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 SUPERFAMILY SSF47203 229 383 3.87E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 6.4E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Gene3D G3DSA:1.20.140.10 221 387 2.5E-62 T 28-03-2018 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 120 1.9E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 381 4.0E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 PIRSF PIRSF016578 238 387 1.4E-13 T 28-03-2018 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 PIRSF PIRSF016578 1 195 2.7E-9 T 28-03-2018 SmaCSM2_RS01185 94deb007b3bebe2d6e8db270c77deaba 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 SUPERFAMILY SSF50715 367 578 8.89E-72 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 580 53.169 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Gene3D G3DSA:2.40.240.10 492 578 2.5E-30 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Gene3D G3DSA:1.10.1160.10 288 365 1.2E-31 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Gene3D G3DSA:3.40.50.620 38 161 1.1E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Gene3D G3DSA:3.40.50.620 165 287 2.0E-16 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 SUPERFAMILY SSF52374 22 363 6.52E-92 T 28-03-2018 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Gene3D G3DSA:2.40.240.10 371 491 5.7E-46 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 38 581 1.2E-210 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 367 559 7.1E-57 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 53 4.0E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 PRINTS PR00987 Glutamyl-tRNA synthetase signature 70 83 4.0E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 PRINTS PR00987 Glutamyl-tRNA synthetase signature 219 229 4.0E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 280 348 9.1E-15 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS03625 1aff2b2b78ef0c489e3d0ca5fcd3aba1 582 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 38 260 1.8E-79 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS10880 7b369aa332fa98e53b828e321f198e15 422 Pfam PF05275 Copper resistance protein B precursor (CopB) 218 422 2.0E-87 T 28-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 SmaCSM2_RS10880 7b369aa332fa98e53b828e321f198e15 422 Gene3D G3DSA:2.40.128.130 213 417 2.7E-6 T 28-03-2018 SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 PRINTS PR01438 Universal stress protein signature 126 148 5.7E-18 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 PRINTS PR01438 Universal stress protein signature 2 20 5.7E-18 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 PRINTS PR01438 Universal stress protein signature 108 120 5.7E-18 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 Pfam PF00582 Universal stress protein family 1 148 6.1E-33 T 28-03-2018 IPR006016 UspA GO:0006950 SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 Gene3D G3DSA:3.40.50.620 1 148 3.7E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS21225 9ecb6eff55aa85019ff443f27196e888 148 SUPERFAMILY SSF52402 2 148 6.03E-35 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Gene3D G3DSA:3.30.70.870 405 497 5.3E-37 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Pfam PF14492 Elongation Factor G, domain II 411 484 5.6E-35 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Pfam PF00679 Elongation factor G C-terminus 620 707 1.3E-29 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Gene3D G3DSA:2.40.30.10 283 404 1.2E-30 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Hamap MF_00054_B Elongation factor G [fusA]. 6 713 108.649 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF50447 312 409 4.95E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF50447 256 281 4.95E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Gene3D G3DSA:3.40.50.300 1 282 1.9E-57 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Pfam PF03764 Elongation factor G, domain IV 486 618 3.1E-41 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF52540 6 288 4.01E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 712 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Pfam PF03144 Elongation factor Tu domain 2 331 398 1.8E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF54980 623 711 5.28E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF54211 486 619 1.77E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SMART SM00889 487 618 1.1E-64 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Gene3D G3DSA:3.30.70.240 634 713 2.2E-29 T 28-03-2018 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Gene3D G3DSA:3.30.230.10 498 633 1.0E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 5.5E-66 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SUPERFAMILY SSF54980 411 488 6.47E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 SMART SM00838 620 709 2.5E-51 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS03975 e762278dfad028d93ed0fcf3113b9ed9 713 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 186 3.3E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF49452 31 106 1.02E-7 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 Pfam PF13620 Carboxypeptidase regulatory-like domain 47 106 1.4E-7 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 Gene3D G3DSA:2.60.40.1120 31 110 1.7E-8 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 Pfam PF00593 TonB dependent receptor 381 1016 9.6E-17 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF56935 629 670 7.33E-62 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF56935 943 1018 7.33E-62 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF56935 116 589 7.33E-62 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF56935 732 775 7.33E-62 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 SUPERFAMILY SSF56935 810 916 7.33E-62 T 28-03-2018 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 Gene3D G3DSA:2.40.170.20 279 1018 2.9E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14405 2475e7320661ae6a0564cd69cb6ddcb3 1018 Gene3D G3DSA:2.170.130.10 134 262 4.4E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS07190 a1bb60bc6a783c1130f4077075bc4e66 113 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 88 1.2E-18 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS07190 a1bb60bc6a783c1130f4077075bc4e66 113 SUPERFAMILY SSF69118 4 109 3.4E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS07190 a1bb60bc6a783c1130f4077075bc4e66 113 Gene3D G3DSA:1.20.1290.10 3 113 2.1E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS07190 a1bb60bc6a783c1130f4077075bc4e66 113 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 105 6.2E-21 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SMART SM00052 452 699 1.8E-106 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SMART SM00304 218 271 7.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Gene3D G3DSA:3.30.450.20 41 179 2.6E-4 T 28-03-2018 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SUPERFAMILY SSF158472 218 267 4.05E-9 T 28-03-2018 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Pfam PF00672 HAMP domain 218 267 1.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Pfam PF17203 Single cache domain 3 57 175 1.0E-7 T 28-03-2018 IPR033463 Single cache domain 3 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SMART SM00267 266 442 1.1E-51 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Pfam PF00563 EAL domain 458 694 6.7E-72 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Gene3D G3DSA:3.30.70.270 271 449 3.9E-53 T 28-03-2018 SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 277 437 5.4E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 275 441 2.7E-36 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SUPERFAMILY SSF141868 457 705 4.32E-86 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 Gene3D G3DSA:3.20.20.450 450 707 1.4E-96 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS14705 a1af82c55cb74b92ccc3870fb25fd150 708 SUPERFAMILY SSF55073 282 443 7.59E-44 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Gene3D G3DSA:1.10.3090.10 180 436 2.0E-37 T 28-03-2018 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Gene3D G3DSA:3.30.460.10 22 179 1.4E-49 T 28-03-2018 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Pfam PF12626 Polymerase A arginine-rich C-terminus 326 449 3.8E-33 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 3 449 37.857 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 SUPERFAMILY SSF81301 27 180 4.03E-39 T 28-03-2018 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Pfam PF01743 Poly A polymerase head domain 56 182 1.1E-35 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 SUPERFAMILY SSF81891 183 392 1.03E-44 T 28-03-2018 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 25 453 3.7E-153 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 SmaCSM2_RS08335 78a213c4f891cf7e55c38f43ead3dfed 459 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 210 272 3.2E-20 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Gene3D G3DSA:1.10.8.60 657 755 6.8E-21 T 28-03-2018 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SMART SM00382 210 355 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SMART SM00382 491 627 5.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SUPERFAMILY SSF52540 441 748 6.07E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 313 2.5E-10 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 650 1.6E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Gene3D G3DSA:1.10.1780.10 1 142 9.4E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Gene3D G3DSA:3.40.50.300 455 656 3.4E-43 T 28-03-2018 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SMART SM01086 657 746 6.4E-33 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Gene3D G3DSA:1.10.8.60 355 454 1.4E-26 T 28-03-2018 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SUPERFAMILY SSF81923 1 141 8.63E-58 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 7.7E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Gene3D G3DSA:3.40.50.300 169 354 8.1E-25 T 28-03-2018 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 3.1E-16 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SmaCSM2_RS10395 b0c2a72e807c6cbe75549ab458a247bc 761 SUPERFAMILY SSF52540 172 430 6.0E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10095 1b70ab5958bf7055f910924102ef9948 295 SUPERFAMILY SSF52540 27 290 1.43E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10095 1b70ab5958bf7055f910924102ef9948 295 Gene3D G3DSA:3.40.50.300 26 270 1.8E-52 T 28-03-2018 SmaCSM2_RS10095 1b70ab5958bf7055f910924102ef9948 295 PIRSF PIRSF003092 6 292 1.9E-81 T 28-03-2018 IPR025501 ATP binding protein MinD SmaCSM2_RS10095 1b70ab5958bf7055f910924102ef9948 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 29 247 1.1E-20 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 Gene3D G3DSA:3.40.190.10 89 176 1.6E-14 T 28-03-2018 SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 1.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 Gene3D G3DSA:3.40.190.10 177 269 1.9E-14 T 28-03-2018 SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 SUPERFAMILY SSF46785 3 113 2.92E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 SUPERFAMILY SSF53850 89 300 9.05E-42 T 28-03-2018 SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 Pfam PF03466 LysR substrate binding domain 89 299 3.2E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS08590 1216977ba535c0b5ec060d0fa246258b 343 Gene3D G3DSA:1.10.10.10 1 85 2.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 Pfam PF14718 Soluble lytic murein transglycosylase L domain 405 463 5.6E-12 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 SUPERFAMILY SSF53955 482 640 7.03E-47 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 Gene3D G3DSA:1.25.20.10 30 387 4.5E-36 T 28-03-2018 SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 Gene3D G3DSA:1.10.1240.20 403 452 1.7E-16 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 SUPERFAMILY SSF48435 31 477 1.96E-102 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 Gene3D G3DSA:1.10.530.10 453 627 1.6E-37 T 28-03-2018 SmaCSM2_RS18170 b4a35486baa1838f86952848f290da3d 661 Pfam PF01464 Transglycosylase SLT domain 484 597 1.3E-25 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 Pfam PF01494 FAD binding domain 10 312 4.4E-13 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 3.3E-13 T 28-03-2018 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 3.3E-13 T 28-03-2018 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 3.3E-13 T 28-03-2018 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 SUPERFAMILY SSF51905 264 346 1.0E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 SUPERFAMILY SSF51905 9 170 1.0E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 Gene3D G3DSA:3.30.9.10 152 323 3.4E-20 T 28-03-2018 SmaCSM2_RS07355 2eb876ad2aa38b0ff3c7600b2be9bb19 368 Gene3D G3DSA:3.50.50.60 2 151 2.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 Gene3D G3DSA:1.10.10.10 3 84 4.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 SUPERFAMILY SSF46785 3 112 4.59E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 Gene3D G3DSA:3.40.190.10 175 261 2.1E-25 T 28-03-2018 SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 Pfam PF03466 LysR substrate binding domain 88 293 3.9E-48 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 SUPERFAMILY SSF53850 89 295 2.71E-48 T 28-03-2018 SmaCSM2_RS12975 3b569c30655b81ec2cb70df65bd8bf09 301 Gene3D G3DSA:3.40.190.10 88 174 1.2E-14 T 28-03-2018 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 SMART SM00478 50 204 6.8E-42 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 SUPERFAMILY SSF48150 15 238 6.75E-73 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Pfam PF00633 Helix-hairpin-helix motif 111 138 1.6E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Gene3D G3DSA:1.10.1670.10 130 238 8.3E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Gene3D G3DSA:3.90.79.10 239 367 3.5E-11 T 28-03-2018 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 206 222 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 47 177 1.8E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 ProSitePatterns PS01155 Endonuclease III family signature. 113 142 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Gene3D G3DSA:1.10.340.30 32 129 3.0E-32 T 28-03-2018 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 17 288 2.9E-104 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 SUPERFAMILY SSF55811 234 356 1.52E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS08485 e6bd36937b91a98d22e536aa63a4ec30 374 Pfam PF14815 NUDIX domain 249 356 1.6E-23 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS01210 02f2c35381b38bcc9c579a0e19fe09d8 318 Pfam PF01545 Cation efflux family 18 227 2.3E-31 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS01210 02f2c35381b38bcc9c579a0e19fe09d8 318 SUPERFAMILY SSF161111 12 226 2.75E-24 T 28-03-2018 SmaCSM2_RS01210 02f2c35381b38bcc9c579a0e19fe09d8 318 Gene3D G3DSA:1.20.1510.10 14 229 1.2E-17 T 28-03-2018 SmaCSM2_RS15140 ef7015fd133fca52ef7decba79453f79 364 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 24 358 24.122 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15140 ef7015fd133fca52ef7decba79453f79 364 Pfam PF00146 NADH dehydrogenase 31 352 1.1E-117 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15140 ef7015fd133fca52ef7decba79453f79 364 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 229 242 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 SUPERFAMILY SSF47384 238 308 9.81E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 Gene3D G3DSA:3.30.565.10 326 460 7.8E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 SMART SM00304 201 253 4.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 457 1.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 SMART SM00388 254 312 6.0E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 SUPERFAMILY SSF55874 313 458 4.19E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 7.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 7.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 7.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 Pfam PF00672 HAMP domain 201 250 1.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 SMART SM00387 351 460 1.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06830 011ecb688ac8870f6b3edcdce966e22d 469 Gene3D G3DSA:1.10.287.130 244 325 7.3E-7 T 28-03-2018 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 202 5.6E-36 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 2.0E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PIRSF PIRSF000349 1 209 3.3E-76 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 5.4E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 5.4E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 5.4E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PRINTS PR01703 Manganese superoxide dismutase signature 167 179 5.4E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 5.4E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 Gene3D G3DSA:1.10.287.990 20 89 4.2E-30 T 28-03-2018 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 SUPERFAMILY SSF54719 93 206 1.31E-41 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 169 176 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS12540 cd73af06717afff566ef81f9cdd3c31c 209 SUPERFAMILY SSF46609 1 89 4.32E-36 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00086 553 593 2.0 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00086 427 468 5.6 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Pfam PF13188 PAS domain 480 534 9.9E-9 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SUPERFAMILY SSF55785 368 474 1.8E-14 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00091 480 547 1.4E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00091 355 421 0.12 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Gene3D G3DSA:3.30.450.20 471 609 3.1E-24 T 28-03-2018 SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 477 600 4.4E-19 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 366 474 5.0E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Gene3D G3DSA:3.30.450.20 337 470 6.8E-18 T 28-03-2018 SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Gene3D G3DSA:3.20.20.450 763 1020 1.1E-88 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Pfam PF00563 EAL domain 774 1005 1.4E-67 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Pfam PF08447 PAS fold 378 460 1.6E-10 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SUPERFAMILY SSF55073 610 750 1.57E-14 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00267 593 755 1.0E-8 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Pfam PF00990 Diguanylate cyclase, GGDEF domain 605 749 1.5E-10 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SMART SM00052 765 1010 1.6E-96 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SUPERFAMILY SSF141868 775 1016 1.57E-81 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 SUPERFAMILY SSF55785 466 591 4.34E-22 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS02350 a2da0263469597a0f67d5665ca2ef98f 1020 Gene3D G3DSA:3.30.70.270 610 762 3.4E-22 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 SUPERFAMILY SSF51120 979 1140 4.19E-24 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 PRINTS PR00313 NodO calcium binding signature 697 705 6.2E-10 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 PRINTS PR00313 NodO calcium binding signature 829 837 6.2E-10 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 PRINTS PR00313 NodO calcium binding signature 867 876 6.2E-10 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 PRINTS PR00313 NodO calcium binding signature 674 685 6.2E-10 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 986 1004 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Gene3D G3DSA:2.60.120.10 997 1032 0.0047 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 SUPERFAMILY SSF51120 809 970 7.59E-25 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1151 1167 0.32 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 823 836 0.078 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 867 882 1.6 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 631 648 0.065 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 838 854 0.7 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1037 1052 4.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 697 712 0.41 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 667 684 7.8E-4 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 650 666 0.034 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 981 997 0.056 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1007 1024 0.11 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 646 664 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 SUPERFAMILY SSF51120 623 798 2.88E-25 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF06594 Haemolysin-type calcium binding protein related domain 757 800 9.2E-9 T 28-03-2018 IPR010566 Haemolysin-type calcium binding-related SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF06594 Haemolysin-type calcium binding protein related domain 927 971 3.1E-12 T 28-03-2018 IPR010566 Haemolysin-type calcium binding-related SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Pfam PF06594 Haemolysin-type calcium binding protein related domain 1097 1141 1.9E-12 T 28-03-2018 IPR010566 Haemolysin-type calcium binding-related SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Gene3D G3DSA:2.150.10.10 1097 1177 3.5E-4 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Gene3D G3DSA:2.150.10.10 2 691 2.8E-26 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Gene3D G3DSA:2.150.10.10 692 790 6.9E-9 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 Gene3D G3DSA:2.150.10.10 791 968 2.7E-21 T 28-03-2018 SmaCSM2_RS16995 b630ff554bc6c3ca058cb71284e83766 1182 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 816 834 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 Gene3D G3DSA:3.40.190.10 179 265 7.5E-21 T 28-03-2018 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 SUPERFAMILY SSF53850 93 298 5.25E-39 T 28-03-2018 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 SUPERFAMILY SSF46785 10 115 6.39E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 Gene3D G3DSA:1.10.10.10 4 91 6.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 Pfam PF03466 LysR substrate binding domain 92 297 2.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 2.7E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08730 00fe7eb0ef91bf15027efbe6b34f1087 305 Gene3D G3DSA:3.40.190.10 92 178 5.9E-21 T 28-03-2018 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 SMART SM00987 316 476 2.8E-33 T 28-03-2018 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 SMART SM00986 316 476 2.8E-33 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 20 247 1.3E-66 T 28-03-2018 IPR023875 DNA metabolism protein, putative SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 249 476 2.9E-88 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 SUPERFAMILY SSF52141 290 472 1.57E-53 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 Pfam PF03167 Uracil DNA glycosylase superfamily 316 473 1.1E-36 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 Gene3D G3DSA:3.40.470.10 277 480 4.9E-58 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 302 463 2.1E-39 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SmaCSM2_RS02630 f0462d29102962cca2cf0ff00e3f85d2 486 Pfam PF13566 Domain of unknown function (DUF4130 89 246 1.4E-45 T 28-03-2018 IPR025404 Domain of unknown function DUF4130 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 27 84 8.3E-23 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 SUPERFAMILY SSF81333 12 86 4.05E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 PRINTS PR00124 ATP synthase C subunit signature 57 82 2.6E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 PRINTS PR00124 ATP synthase C subunit signature 19 38 2.6E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 PRINTS PR00124 ATP synthase C subunit signature 40 55 2.6E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 Gene3D G3DSA:1.20.20.10 11 86 5.1E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 Pfam PF00137 ATP synthase subunit C 18 81 2.5E-8 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 ProSitePatterns PS00605 ATP synthase c subunit signature. 47 68 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18715 ea23358d15569d59d11b3cf2ac3c1de4 101 Hamap MF_01396 ATP synthase subunit c [atpH]. 17 82 13.765 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 SUPERFAMILY SSF56519 58 224 2.75E-46 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 Pfam PF00905 Penicillin binding protein transpeptidase domain 250 546 1.5E-80 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 Gene3D G3DSA:3.90.1310.10 31 225 1.3E-47 T 28-03-2018 SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 Gene3D G3DSA:3.40.710.10 226 570 8.4E-86 T 28-03-2018 SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 SUPERFAMILY SSF56601 178 566 2.32E-92 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS03235 db35bc7730d8c468546606c7b1465fb7 614 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 209 1.9E-19 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SMART SM00869 3353 3616 1.1E-22 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2910 3073 1.32E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 2710 2932 1.6E-4 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 2505 2709 5.6E-4 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 2975 3254 0.057 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 1566 1767 0.023 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 2233 2504 0.14 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:2.160.20.20 2031 2232 9.2E-5 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1225 1256 1.3E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1324 1355 5.7E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1598 1629 3.8E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1050 1081 3.2E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1967 1997 4.7E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 962 993 9.3E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2343 2374 1.5E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2666 2697 2.2E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1412 1443 5.9E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2942 2973 4.7E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1500 1531 1.2E-10 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2804 2830 1.1E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2528 2555 1.9E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 690 721 2.4E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2245 2276 1.4E-10 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1780 1811 1.3E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2873 2904 7.8E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1138 1169 8.6E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2735 2766 8.0E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2597 2628 1.4E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2430 2460 7.1E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 876 907 4.6E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2063 2094 5.2E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 3011 3037 1.0E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1879 1910 2.2E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1684 1715 1.8E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 778 809 2.0E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2149 2180 1.2E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 505 536 6.6E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2722 2855 5.02E-12 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 394 723 3.14E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 757 822 3.14E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2847 2926 8.79E-9 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2736 2766 3.1E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2150 2179 3.3E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1139 1167 1.9E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2598 2628 3.2E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1880 1909 4.9E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2529 2559 2.5E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 3012 3042 1.2E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1413 1442 0.0012 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 603 632 0.069 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1226 1255 2.5E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1325 1354 1.7E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2432 2460 1.2E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1968 1997 2.6E-10 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 779 808 4.6E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 506 535 6.4E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1501 1530 4.8E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1051 1080 4.7E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1599 1628 1.9E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 691 720 2.9E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2344 2373 1.8E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2943 2973 9.5E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1781 1810 4.7E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 1685 1714 3.5E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 877 906 6.9E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2805 2835 5.4E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2667 2697 2.9E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2874 2904 1.6E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 963 990 8.7E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2246 2275 1.4E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF12951 Passenger-associated-transport-repeat 2064 2093 1.0E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 1303 1381 1.07E-18 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 1117 1258 1.07E-18 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 851 991 1.07E-18 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 1021 1071 1.07E-18 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2641 2718 2.2E-8 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF103515 3317 3626 2.09E-45 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2566 2645 1.07E-5 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 2224 2512 2.83E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:3.30.1390.40 1501 1519 0.0074 T 28-03-2018 SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Gene3D G3DSA:3.30.1390.40 1968 1987 0.03 T 28-03-2018 SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 3053 3240 2.39E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 1860 2232 3.04E-34 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 SUPERFAMILY SSF51126 1478 1856 8.48E-26 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS04540 82e715f29c9c752db7e812c43a63b502 3626 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 2.8E-9 T 28-03-2018 IPR024973 ESPR domain SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 2.8E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 PRINTS PR00758 Arsenical pump membrane protein signature 107 131 2.8E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 2.8E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 PRINTS PR00758 Arsenical pump membrane protein signature 358 383 2.8E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 PRINTS PR00758 Arsenical pump membrane protein signature 391 415 2.8E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SmaCSM2_RS11295 ce0f0462b3fb9cca46c8c30222ad8b44 415 Pfam PF03600 Citrate transporter 31 339 4.9E-29 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SmaCSM2_RS08520 4c385ae2d2f9a8c2e4a7add40ae43823 93 Pfam PF00037 4Fe-4S binding domain 5 24 1.8E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS08520 4c385ae2d2f9a8c2e4a7add40ae43823 93 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS08520 4c385ae2d2f9a8c2e4a7add40ae43823 93 Gene3D G3DSA:3.30.70.20 52 83 0.061 T 28-03-2018 SmaCSM2_RS08520 4c385ae2d2f9a8c2e4a7add40ae43823 93 SUPERFAMILY SSF54862 6 75 1.52E-18 T 28-03-2018 SmaCSM2_RS08520 4c385ae2d2f9a8c2e4a7add40ae43823 93 Gene3D G3DSA:3.30.70.20 3 51 3.4E-12 T 28-03-2018 SmaCSM2_RS03795 cc78fdd7c1ecb67a60f94ef12f553e40 260 Gene3D G3DSA:3.40.50.300 1 249 4.9E-88 T 28-03-2018 SmaCSM2_RS03795 cc78fdd7c1ecb67a60f94ef12f553e40 260 SUPERFAMILY SSF52540 35 220 5.8E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03795 cc78fdd7c1ecb67a60f94ef12f553e40 260 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 3 229 2.4E-103 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 SmaCSM2_RS03795 cc78fdd7c1ecb67a60f94ef12f553e40 260 PIRSF PIRSF028756 1 254 1.5E-109 T 28-03-2018 IPR016898 Polyphosphate kinase 2 SmaCSM2_RS03795 cc78fdd7c1ecb67a60f94ef12f553e40 260 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 4 228 2.3E-93 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 Pfam PF00072 Response regulator receiver domain 144 252 1.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 Gene3D G3DSA:3.40.50.2300 136 264 3.9E-29 T 28-03-2018 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 432 6.1E-52 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SUPERFAMILY SSF52172 142 270 9.53E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 Gene3D G3DSA:3.30.70.270 265 437 1.5E-54 T 28-03-2018 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SUPERFAMILY SSF55073 277 432 5.73E-47 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 Gene3D G3DSA:3.40.50.2300 17 135 2.2E-9 T 28-03-2018 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 429 4.8E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SMART SM00448 141 255 8.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SMART SM00448 19 132 0.014 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SMART SM00267 261 433 1.8E-54 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS07000 3459c29dac233fc5ffbe3ec518a568f7 447 SUPERFAMILY SSF52172 19 140 1.11E-11 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 Pfam PF03466 LysR substrate binding domain 89 291 1.1E-34 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 SUPERFAMILY SSF46785 1 113 1.47E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 Gene3D G3DSA:3.40.190.10 177 268 4.5E-21 T 28-03-2018 SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 SUPERFAMILY SSF53850 90 294 5.97E-37 T 28-03-2018 SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 Gene3D G3DSA:3.40.190.10 90 176 3.7E-21 T 28-03-2018 SmaCSM2_RS06775 7a219d4dc58b92586f561e2d68ef696a 299 Gene3D G3DSA:1.10.10.10 1 88 7.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05190 729f0d5fceb83fedf0fbe112c45f0758 235 Pfam PF00308 Bacterial dnaA protein 99 200 2.8E-5 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA SmaCSM2_RS05190 729f0d5fceb83fedf0fbe112c45f0758 235 Gene3D G3DSA:3.40.50.300 9 161 1.6E-9 T 28-03-2018 SmaCSM2_RS05190 729f0d5fceb83fedf0fbe112c45f0758 235 SUPERFAMILY SSF52540 13 207 2.0E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05190 729f0d5fceb83fedf0fbe112c45f0758 235 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 5 229 3.9E-65 T 28-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 SmaCSM2_RS05190 729f0d5fceb83fedf0fbe112c45f0758 235 Gene3D G3DSA:1.10.8.60 163 230 2.7E-9 T 28-03-2018 SmaCSM2_RS13315 3ba343c12a840e4a7085273375d53251 190 Hamap MF_00045 Oligoribonuclease [orn]. 6 184 41.177 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 SmaCSM2_RS13315 3ba343c12a840e4a7085273375d53251 190 Pfam PF00929 Exonuclease 12 173 1.5E-29 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS13315 3ba343c12a840e4a7085273375d53251 190 Gene3D G3DSA:3.30.420.10 5 181 4.1E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS13315 3ba343c12a840e4a7085273375d53251 190 SUPERFAMILY SSF53098 8 181 1.77E-45 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS13315 3ba343c12a840e4a7085273375d53251 190 SMART SM00479 10 183 2.7E-16 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 346 426 7.3E-30 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 SMART SM00928 343 388 3.2E-26 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 62 233 8.0E-43 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 Gene3D G3DSA:3.10.560.10 248 298 9.6E-5 T 28-03-2018 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 356 367 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 SUPERFAMILY SSF142984 255 338 7.98E-22 T 28-03-2018 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 181 196 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 21 429 2.5E-194 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 Pfam PF10531 SLBB domain 257 305 5.8E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 SUPERFAMILY SSF142019 19 251 3.92E-78 T 28-03-2018 SmaCSM2_RS15150 939ed6741250b11aff903ef518f97db5 446 SUPERFAMILY SSF140490 339 436 8.76E-35 T 28-03-2018 SmaCSM2_RS07105 957318bad2162dd1a73098a4ba0fa2f6 292 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS07105 957318bad2162dd1a73098a4ba0fa2f6 292 Gene3D G3DSA:3.40.50.300 1 267 2.6E-68 T 28-03-2018 SmaCSM2_RS07105 957318bad2162dd1a73098a4ba0fa2f6 292 SUPERFAMILY SSF52540 1 205 3.88E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07105 957318bad2162dd1a73098a4ba0fa2f6 292 SMART SM00382 10 191 8.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS07105 957318bad2162dd1a73098a4ba0fa2f6 292 Pfam PF00005 ABC transporter 1 145 7.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 SMART SM00490 261 342 6.2E-30 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 Gene3D G3DSA:3.40.50.300 226 466 7.5E-44 T 28-03-2018 SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 SMART SM00487 20 225 3.2E-61 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 SUPERFAMILY SSF52540 76 362 1.61E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 Pfam PF00270 DEAD/DEAH box helicase 25 198 2.0E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 Pfam PF00271 Helicase conserved C-terminal domain 234 342 2.4E-28 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS02615 4d40cad29d41453f8cc46e58d4795b89 473 Gene3D G3DSA:3.40.50.300 10 225 1.1E-60 T 28-03-2018 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 Gene3D G3DSA:1.10.8.10 7 84 9.7E-22 T 28-03-2018 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 Pfam PF05175 Methyltransferase small domain 106 199 5.0E-15 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 Gene3D G3DSA:3.40.50.150 85 285 3.4E-42 T 28-03-2018 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 279 6.5E-90 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 SUPERFAMILY SSF53335 25 281 3.85E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 9 283 45.328 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 282 1.4E-76 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SmaCSM2_RS03665 c4b588c5a44e266027cb80c3eaaeaba6 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 188 194 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS04820 3c10f01e3d2d1c7db76cdc3519da89e3 353 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 9 344 2.5E-82 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SmaCSM2_RS04820 3c10f01e3d2d1c7db76cdc3519da89e3 353 Gene3D G3DSA:3.30.160.60 310 345 4.5E-12 T 28-03-2018 SmaCSM2_RS04820 3c10f01e3d2d1c7db76cdc3519da89e3 353 Gene3D G3DSA:3.30.160.60 84 115 3.2E-7 T 28-03-2018 SmaCSM2_RS04820 3c10f01e3d2d1c7db76cdc3519da89e3 353 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 10 341 32.247 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SmaCSM2_RS04820 3c10f01e3d2d1c7db76cdc3519da89e3 353 Pfam PF02618 YceG-like family 49 336 1.1E-75 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SmaCSM2_RS04970 bae731ee4e74ac85c1585e85845e0fe9 225 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 22 221 7.3E-69 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SmaCSM2_RS04970 bae731ee4e74ac85c1585e85845e0fe9 225 Pfam PF01168 Alanine racemase, N-terminal domain 7 222 1.7E-33 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS04970 bae731ee4e74ac85c1585e85845e0fe9 225 SUPERFAMILY SSF51419 4 219 3.93E-73 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS04970 bae731ee4e74ac85c1585e85845e0fe9 225 PIRSF PIRSF004848 5 225 8.2E-74 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SmaCSM2_RS04970 bae731ee4e74ac85c1585e85845e0fe9 225 Gene3D G3DSA:3.20.20.10 1 225 7.0E-69 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS04120 e582f904b745977add4066f2312c0e68 168 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 4 168 22.586 T 28-03-2018 IPR022920 Disulphide bond formation protein DsbB SmaCSM2_RS04120 e582f904b745977add4066f2312c0e68 168 SUPERFAMILY SSF158442 12 160 9.94E-42 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain SmaCSM2_RS04120 e582f904b745977add4066f2312c0e68 168 Gene3D G3DSA:1.20.1550.10 7 168 1.1E-42 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain SmaCSM2_RS04120 e582f904b745977add4066f2312c0e68 168 Pfam PF02600 Disulfide bond formation protein DsbB 9 160 1.5E-38 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 SmaCSM2_RS00105 7227649f04fc2dcdecfc1d98e4a024c1 433 Pfam PF00589 Phage integrase family 212 406 6.5E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS00105 7227649f04fc2dcdecfc1d98e4a024c1 433 SUPERFAMILY SSF56349 65 406 9.12E-25 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS00105 7227649f04fc2dcdecfc1d98e4a024c1 433 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 66 142 9.5E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SmaCSM2_RS00105 7227649f04fc2dcdecfc1d98e4a024c1 433 Gene3D G3DSA:1.10.150.130 62 161 5.1E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS00105 7227649f04fc2dcdecfc1d98e4a024c1 433 Gene3D G3DSA:1.10.443.10 179 409 7.2E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 2.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 2.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 2.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 SUPERFAMILY SSF52172 21 153 8.82E-20 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 Pfam PF00072 Response regulator receiver domain 25 138 1.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 SMART SM00421 169 226 6.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 SUPERFAMILY SSF46894 159 225 4.42E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 171 223 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 SMART SM00448 21 138 2.7E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 Gene3D G3DSA:3.40.50.2300 21 149 1.6E-19 T 28-03-2018 SmaCSM2_RS01555 d33715bfff07f2db53dc5738b4e96d47 232 Gene3D G3DSA:1.10.10.10 150 229 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17200 03e32dc95894e4e0419a99071bb94ecf 413 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 330 405 3.7E-14 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS17200 03e32dc95894e4e0419a99071bb94ecf 413 SUPERFAMILY SSF74653 327 404 2.88E-19 T 28-03-2018 SmaCSM2_RS17200 03e32dc95894e4e0419a99071bb94ecf 413 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 328 405 3.5E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS17200 03e32dc95894e4e0419a99071bb94ecf 413 Gene3D G3DSA:3.30.1150.10 158 413 1.2E-18 T 28-03-2018 SmaCSM2_RS17200 03e32dc95894e4e0419a99071bb94ecf 413 Pfam PF05569 BlaR1 peptidase M56 136 260 1.1E-32 T 28-03-2018 IPR008756 Peptidase M56 SmaCSM2_RS13390 a2adc0a19d8adf13d33922dc5f69b337 382 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 62 289 9.3E-33 T 28-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 170 332 1.4E-33 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 SUPERFAMILY SSF53671 2 335 3.54E-73 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 287 296 1.1E-12 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 1.1E-12 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 1.1E-12 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 Gene3D G3DSA:3.40.50.1370 1 158 1.2E-39 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 Gene3D G3DSA:3.40.50.1370 159 335 1.9E-40 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 161 1.3E-36 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 35 57 4.7E-11 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 315 329 4.7E-11 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS14630 de7025d17fecf5eefdb98861db805516 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 147 164 4.7E-11 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 SUPERFAMILY SSF46785 1 111 1.09E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 SUPERFAMILY SSF53850 88 295 9.5E-44 T 28-03-2018 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 Pfam PF03466 LysR substrate binding domain 87 287 4.1E-48 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 Gene3D G3DSA:3.40.190.10 176 264 1.6E-24 T 28-03-2018 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 Gene3D G3DSA:3.40.190.10 88 175 5.0E-25 T 28-03-2018 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.0E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03650 05dd1e4a1fb93fb20c066f66dce24973 320 Gene3D G3DSA:1.10.10.10 1 86 2.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.259 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.1E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.1E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.1E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.1E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 Gene3D G3DSA:1.20.5.1150 16 52 1.0E-17 T 28-03-2018 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.8E-24 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 Pfam PF01165 Ribosomal protein S21 3 56 5.6E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01860 35b943693d9b9050dbf636e6ca69f3cd 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 44 1.0E-9 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:1.10.287.130 697 754 3.2E-20 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF00512 His Kinase A (phospho-acceptor) domain 693 758 1.3E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF47226 1048 1061 1.23E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF47226 1091 1186 1.23E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SMART SM00388 693 758 4.5E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SMART SM00448 949 1065 2.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF55785 589 674 2.07E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF55874 747 921 1.2E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 806 921 5.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.40.50.2300 944 1091 2.5E-33 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF08447 PAS fold 589 662 7.8E-6 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.40.190.10 388 466 1.9E-9 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF53850 46 267 6.79E-35 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 263 2.6E-23 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 288 493 2.0E-19 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.30.565.10 762 932 6.8E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF53850 286 507 2.44E-29 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SMART SM00387 805 923 1.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 883 901 7.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 862 7.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 907 920 7.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 866 876 7.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Pfam PF00072 Response regulator receiver domain 951 1065 4.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF47384 677 758 4.9E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.40.190.10 172 284 5.2E-4 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SMART SM00062 45 266 1.9E-11 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SMART SM00062 287 507 1.1E-13 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.40.190.10 285 387 5.1E-9 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.30.450.20 571 696 4.7E-16 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 SUPERFAMILY SSF52172 948 1073 2.13E-32 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:3.40.190.10 40 171 1.5E-13 T 28-03-2018 SmaCSM2_RS00825 03046a07c15e8d649e2ede0c9c1c5886 1199 Gene3D G3DSA:1.20.120.160 1092 1199 1.8E-8 T 28-03-2018 SmaCSM2_RS03690 b870ce2575afeedca51900373414d9af 265 Pfam PF05013 N-formylglutamate amidohydrolase 30 237 7.8E-45 T 28-03-2018 IPR007709 N-formylglutamate amidohydrolase SmaCSM2_RS03690 b870ce2575afeedca51900373414d9af 265 Gene3D G3DSA:3.40.630.40 20 262 1.8E-66 T 28-03-2018 SmaCSM2_RS03690 b870ce2575afeedca51900373414d9af 265 SUPERFAMILY SSF53187 14 261 2.67E-76 T 28-03-2018 SmaCSM2_RS03690 b870ce2575afeedca51900373414d9af 265 PIRSF PIRSF029730 10 264 2.0E-99 T 28-03-2018 IPR011227 Uncharacterised conserved protein UCP029730 SmaCSM2_RS19175 5efa9c29512fc997000124a06a9ceaeb 357 Pfam PF00793 DAHP synthetase I family 40 338 4.8E-101 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS19175 5efa9c29512fc997000124a06a9ceaeb 357 SUPERFAMILY SSF51569 7 348 5.55E-138 T 28-03-2018 SmaCSM2_RS19175 5efa9c29512fc997000124a06a9ceaeb 357 PIRSF PIRSF001361 1 352 4.2E-161 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SmaCSM2_RS19175 5efa9c29512fc997000124a06a9ceaeb 357 Gene3D G3DSA:3.20.20.70 8 354 1.7E-133 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS19175 5efa9c29512fc997000124a06a9ceaeb 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 2.5E-161 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SmaCSM2_RS12830 6dbe2c919abd8d91e0950d2245a654a2 397 SUPERFAMILY SSF103473 17 394 1.44E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12830 6dbe2c919abd8d91e0950d2245a654a2 397 Gene3D G3DSA:1.20.1250.20 14 203 2.1E-18 T 28-03-2018 SmaCSM2_RS12830 6dbe2c919abd8d91e0950d2245a654a2 397 Gene3D G3DSA:1.20.1250.20 205 397 2.8E-17 T 28-03-2018 SmaCSM2_RS12830 6dbe2c919abd8d91e0950d2245a654a2 397 Pfam PF07690 Major Facilitator Superfamily 28 301 2.8E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS12300 c1b8ab9d7db1b75c8d4542e4052f4551 472 Gene3D G3DSA:1.20.1250.20 25 242 1.1E-13 T 28-03-2018 SmaCSM2_RS12300 c1b8ab9d7db1b75c8d4542e4052f4551 472 Gene3D G3DSA:1.20.1250.20 249 471 4.0E-18 T 28-03-2018 SmaCSM2_RS12300 c1b8ab9d7db1b75c8d4542e4052f4551 472 Pfam PF07690 Major Facilitator Superfamily 49 386 8.1E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS12300 c1b8ab9d7db1b75c8d4542e4052f4551 472 TIGRFAM TIGR00886 2A0108: nitrite transporter 40 424 3.4E-103 T 28-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 SmaCSM2_RS12300 c1b8ab9d7db1b75c8d4542e4052f4551 472 SUPERFAMILY SSF103473 23 465 2.88E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS21555 eecb473835f0fddb0b19f4c6f4b4bed5 130 SUPERFAMILY SSF54427 28 129 1.78E-31 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS21555 eecb473835f0fddb0b19f4c6f4b4bed5 130 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 5 130 28.615 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 SmaCSM2_RS21555 eecb473835f0fddb0b19f4c6f4b4bed5 130 Gene3D G3DSA:3.10.450.50 7 130 1.2E-40 T 28-03-2018 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 Pfam PF13454 FAD-NAD(P)-binding 19 170 3.1E-32 T 28-03-2018 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 Gene3D G3DSA:3.50.50.60 1 160 1.2E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 Gene3D G3DSA:3.50.50.60 161 383 4.5E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 SUPERFAMILY SSF51905 15 241 2.73E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.2E-8 T 28-03-2018 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 1.2E-8 T 28-03-2018 SmaCSM2_RS21260 1d0dfb620a27cdd594270a92f47e5efc 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 205 223 1.2E-8 T 28-03-2018 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 SUPERFAMILY SSF88946 11 95 5.1E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 Gene3D G3DSA:1.10.10.10 77 166 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 Gene3D G3DSA:1.10.1740.10 5 76 1.8E-17 T 28-03-2018 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 SUPERFAMILY SSF88659 94 165 1.23E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 Pfam PF04542 Sigma-70 region 2 15 80 1.3E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 165 2.3E-29 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS13035 41c94451593edc0af0bc1dacde405a7c 169 Pfam PF08281 Sigma-70, region 4 113 163 2.0E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 SUPERFAMILY SSF102712 2 98 1.31E-20 T 28-03-2018 SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 SMART SM00232 1 124 0.0053 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 Pfam PF14464 Prokaryotic homologs of the JAB domain 5 98 6.7E-18 T 28-03-2018 IPR028090 JAB domain, prokaryotic SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 SUPERFAMILY SSF54001 118 241 1.24E-16 T 28-03-2018 SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 Gene3D G3DSA:3.40.140.10 1 106 8.8E-13 T 28-03-2018 SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 Pfam PF00877 NlpC/P60 family 125 239 6.1E-18 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SmaCSM2_RS01265 fcf8d38689a0976a6fe24f7890c19325 246 Gene3D G3DSA:3.90.1720.10 107 246 2.5E-14 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:3.30.2090.10 186 275 3.6E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82866 812 1037 6.8E-43 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 630 644 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 5.4E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82714 185 274 7.06E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82693 574 678 5.02E-22 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:3.30.70.1440 679 775 3.0E-19 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Pfam PF00873 AcrB/AcrD/AcrF family 3 1034 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82693 41 134 1.33E-26 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:3.30.70.1430 576 678 1.1E-17 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:1.20.1640.10 835 1038 2.6E-37 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:1.20.1640.10 277 500 1.1E-48 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82714 729 815 2.88E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82693 138 184 3.66E-28 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82693 276 332 3.66E-28 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 Gene3D G3DSA:3.30.70.1430 40 142 2.9E-28 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 SUPERFAMILY SSF82866 298 498 2.09E-51 T 28-03-2018 SmaCSM2_RS08610 ff19f2e551c153e39a0169cae84f6c58 1056 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1040 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS10450 79a91c3da552e92861bce76c419cd316 647 Pfam PF01841 Transglutaminase-like superfamily 276 349 2.6E-8 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS10450 79a91c3da552e92861bce76c419cd316 647 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 62 228 3.1E-35 T 28-03-2018 IPR024618 Domain of unknown function DUF3857 SmaCSM2_RS10450 79a91c3da552e92861bce76c419cd316 647 SUPERFAMILY SSF54001 270 352 3.24E-9 T 28-03-2018 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 SUPERFAMILY SSF50692 635 757 2.03E-14 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 Pfam PF00384 Molybdopterin oxidoreductase 112 411 1.1E-24 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 PIRSF PIRSF000144 1 760 0.0 T 28-03-2018 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 Pfam PF01568 Molydopterin dinucleotide binding domain 642 749 1.9E-8 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 Gene3D G3DSA:3.40.50.740 113 278 6.1E-33 T 28-03-2018 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 16 755 2.5E-271 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 SUPERFAMILY SSF53706 51 629 4.97E-139 T 28-03-2018 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 Gene3D G3DSA:2.40.40.20 606 755 4.6E-18 T 28-03-2018 SmaCSM2_RS11840 297376069c8bfe182a9ec455e9bc83cb 761 Gene3D G3DSA:3.40.50.740 327 605 1.1E-38 T 28-03-2018 SmaCSM2_RS12460 e0e3d988e877a2f7d0bcf140aa6ce2a9 212 Pfam PF00691 OmpA family 92 196 1.3E-17 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS12460 e0e3d988e877a2f7d0bcf140aa6ce2a9 212 SUPERFAMILY SSF103088 82 201 7.32E-27 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS12460 e0e3d988e877a2f7d0bcf140aa6ce2a9 212 Gene3D G3DSA:3.30.1330.60 40 212 1.8E-33 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Gene3D G3DSA:3.40.50.620 2 233 7.6E-76 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Gene3D G3DSA:3.90.740.10 234 421 2.2E-47 T 28-03-2018 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Gene3D G3DSA:1.10.730.10 583 879 3.2E-52 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Pfam PF08264 Anticodon-binding domain of tRNA 718 841 2.0E-13 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 189 202 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 219 238 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 131 148 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 575 585 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 542 564 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 PRINTS PR00985 Leucyl-tRNA synthetase signature 157 173 2.8E-46 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Gene3D G3DSA:3.40.50.620 422 582 4.5E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 57 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 225 421 2.7E-66 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 175 5.3E-27 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 637 675 7.0E-6 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 590 1.9E-8 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 9 879 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 SUPERFAMILY SSF47323 683 878 7.48E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 SUPERFAMILY SSF52374 8 230 1.92E-146 T 28-03-2018 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 SUPERFAMILY SSF52374 434 684 1.92E-146 T 28-03-2018 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 8 879 23.326 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SmaCSM2_RS15630 7493e260415aa33fa4c2de585802caeb 880 SUPERFAMILY SSF50677 230 433 1.57E-45 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SmaCSM2_RS11425 8d16f2f466798959fa7603f22973f586 292 SUPERFAMILY SSF53474 4 285 2.7E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11425 8d16f2f466798959fa7603f22973f586 292 Gene3D G3DSA:3.40.50.1820 1 291 5.2E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11425 8d16f2f466798959fa7603f22973f586 292 Pfam PF00561 alpha/beta hydrolase fold 34 278 2.2E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS13065 c2fbbde2d92bdd95d0a4d0be8dba059d 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 265 3.1E-26 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS13065 c2fbbde2d92bdd95d0a4d0be8dba059d 300 Gene3D G3DSA:1.20.1510.10 5 212 6.5E-22 T 28-03-2018 SmaCSM2_RS13065 c2fbbde2d92bdd95d0a4d0be8dba059d 300 SUPERFAMILY SSF161111 5 211 3.01E-32 T 28-03-2018 SmaCSM2_RS13065 c2fbbde2d92bdd95d0a4d0be8dba059d 300 Pfam PF01545 Cation efflux family 11 209 7.9E-32 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 Pfam PF00085 Thioredoxin 9 111 1.4E-28 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 Pfam PF14561 Tetratricopeptide repeat 199 285 6.9E-20 T 28-03-2018 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 Gene3D G3DSA:3.40.30.10 2 211 3.6E-38 T 28-03-2018 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 SUPERFAMILY SSF52833 7 111 1.87E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 PRINTS PR00421 Thioredoxin family signature 28 36 2.1E-6 T 28-03-2018 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 PRINTS PR00421 Thioredoxin family signature 76 87 2.1E-6 T 28-03-2018 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 PRINTS PR00421 Thioredoxin family signature 36 45 2.1E-6 T 28-03-2018 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 TIGRFAM TIGR01068 thioredoxin: thioredoxin 15 111 1.8E-31 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SmaCSM2_RS15645 820f8ca12695296a4796c37cf73efdbd 285 Gene3D G3DSA:1.25.40.10 212 264 0.093 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09130 7785efd764dec8fbc0a9fa7e17d3036d 279 Pfam PF17124 ThiJ/PfpI family-like 45 202 1.2E-15 T 28-03-2018 IPR032633 ThiJ/PfpI family-like SmaCSM2_RS09130 7785efd764dec8fbc0a9fa7e17d3036d 279 Gene3D G3DSA:3.40.50.880 4 279 5.2E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09130 7785efd764dec8fbc0a9fa7e17d3036d 279 SUPERFAMILY SSF52317 24 278 2.78E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 SUPERFAMILY SSF55973 110 233 1.84E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 SUPERFAMILY SSF55973 235 397 1.1E-67 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 370 3.5E-180 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 SUPERFAMILY SSF55973 3 109 3.69E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 369 6.9E-69 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Gene3D G3DSA:3.30.300.10 11 138 2.8E-43 T 28-03-2018 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Gene3D G3DSA:3.30.300.10 261 402 2.2E-50 T 28-03-2018 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 55.365 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 PIRSF PIRSF000497 1 401 2.2E-168 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 233 5.7E-43 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 101 7.7E-42 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SmaCSM2_RS03385 a029ffaf2def9620d5570deacd841d2f 403 Gene3D G3DSA:3.30.300.10 139 260 1.6E-41 T 28-03-2018 SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Gene3D G3DSA:2.70.98.10 33 278 3.4E-82 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Gene3D G3DSA:2.60.40.1180 583 683 3.3E-27 T 28-03-2018 SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Gene3D G3DSA:3.20.20.70 279 582 5.1E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 36 282 1.5E-69 T 28-03-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 580 680 9.9E-27 T 28-03-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 SUPERFAMILY SSF51445 318 567 5.69E-6 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS05415 b2182c1b0beb4ab18ad2d5581d008192 683 Pfam PF10566 Glycoside hydrolase 97 287 577 1.4E-108 T 28-03-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 SUPERFAMILY SSF50249 3 191 4.8E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 Hamap MF_00984 Single-stranded DNA-binding protein. 5 112 36.253 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 Pfam PF00436 Single-strand binding protein family 5 108 7.5E-39 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 PIRSF PIRSF002070 157 189 2100.0 T 28-03-2018 SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 PIRSF PIRSF002070 1 139 5.2E-34 T 28-03-2018 SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 Gene3D G3DSA:2.40.50.140 1 123 1.3E-41 T 28-03-2018 SmaCSM2_RS05465 10e04f1e67ba6b8c302d597299bd6b73 191 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 191 8.6E-50 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 17 312 3.4E-96 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 Gene3D G3DSA:3.30.420.40 4 137 6.4E-35 T 28-03-2018 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 SUPERFAMILY SSF53067 17 137 1.17E-31 T 28-03-2018 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 SUPERFAMILY SSF53067 143 314 3.72E-42 T 28-03-2018 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 Gene3D G3DSA:3.30.420.150 139 319 1.5E-33 T 28-03-2018 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 Pfam PF02541 Ppx/GppA phosphatase family 30 313 7.9E-65 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 SUPERFAMILY SSF109604 319 494 7.33E-48 T 28-03-2018 SmaCSM2_RS04315 d769a0f4ccc99239686e887f18b6370f 508 PIRSF PIRSF001267 7 508 1.0E-193 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 SMART SM00448 2 112 4.0E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 Pfam PF00072 Response regulator receiver domain 4 112 1.3E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 SUPERFAMILY SSF52172 2 125 1.57E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 3.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 Gene3D G3DSA:3.40.50.2300 1 117 1.7E-30 T 28-03-2018 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 Gene3D G3DSA:1.10.10.10 118 229 2.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 SUPERFAMILY SSF46894 121 223 2.35E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS02575 e353305ffa7eed5fffe127a26ca229a3 229 SMART SM00862 147 223 1.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 SUPERFAMILY SSF53901 4 268 7.27E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 3.3E-82 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 PIRSF PIRSF000429 1 391 2.3E-108 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 Gene3D G3DSA:3.40.47.10 1 263 6.0E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 Gene3D G3DSA:3.40.47.10 264 388 4.0E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 SUPERFAMILY SSF53901 269 390 3.02E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 2.4E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 1.1E-43 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SmaCSM2_RS15840 734cc12b01b3165b38bc10efea315ff2 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SmaCSM2_RS13430 afe484906c18bd70f0e8e57b56a35e20 259 Pfam PF03524 Conjugal transfer protein 29 255 1.6E-52 T 28-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.30.470.20 119 403 2.8E-66 T 28-03-2018 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1074 13.535 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF52440 558 676 6.19E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 428 548 3.2E-39 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:1.10.1030.10 406 539 2.2E-50 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Pfam PF02142 MGS-like domain 963 1048 3.4E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.40.50.20 4 115 1.1E-37 T 28-03-2018 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.40.50.20 540 655 2.8E-61 T 28-03-2018 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.30.470.20 746 942 4.6E-43 T 28-03-2018 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.40.50.1380 943 1079 4.5E-33 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF52335 942 1077 9.42E-40 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SMART SM01096 425 548 4.5E-73 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.1E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF52440 1 127 2.16E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF56059 128 401 7.25E-108 T 28-03-2018 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1058 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1068 13.308 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SMART SM00851 962 1048 5.6E-32 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF48108 396 555 4.71E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Gene3D G3DSA:3.30.1490.20 656 745 7.1E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.7E-71 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 882 3.7E-40 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS09830 8f0f68eac05a5a9b07a54452931d891f 1080 SUPERFAMILY SSF56059 674 939 2.12E-103 T 28-03-2018 SmaCSM2_RS15420 467f6e218594d0ac218988049d75a488 284 Gene3D G3DSA:3.40.50.300 9 244 3.1E-63 T 28-03-2018 SmaCSM2_RS15420 467f6e218594d0ac218988049d75a488 284 SUPERFAMILY SSF52540 25 270 2.95E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15420 467f6e218594d0ac218988049d75a488 284 Hamap MF_02040 Iron-sulfur cluster carrier protein. 15 266 37.472 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein SmaCSM2_RS15420 467f6e218594d0ac218988049d75a488 284 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 23 265 2.9E-100 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 SmaCSM2_RS15420 467f6e218594d0ac218988049d75a488 284 ProSitePatterns PS01215 Mrp family signature. 129 145 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Gene3D G3DSA:1.10.287.130 302 373 2.3E-6 T 28-03-2018 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SMART SM00387 424 537 1.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SMART SM00388 312 377 8.1E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 141 252 1.2E-9 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Gene3D G3DSA:3.40.50.2300 552 656 5.0E-20 T 28-03-2018 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SMART SM00448 557 669 1.6E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Gene3D G3DSA:3.40.190.10 133 218 1.2E-6 T 28-03-2018 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SUPERFAMILY SSF47226 652 761 7.07E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SUPERFAMILY SSF55874 367 539 9.95E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Gene3D G3DSA:3.30.565.10 381 546 6.5E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 492 1.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 1.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 534 1.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 515 1.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Pfam PF00072 Response regulator receiver domain 560 668 1.1E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SUPERFAMILY SSF47384 316 377 1.88E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Gene3D G3DSA:1.20.120.160 657 768 1.2E-10 T 28-03-2018 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Pfam PF01627 Hpt domain 689 761 2.1E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 535 3.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SUPERFAMILY SSF53850 38 265 6.25E-16 T 28-03-2018 SmaCSM2_RS10520 95320fc57608c6d084a403dfad0aa743 775 SUPERFAMILY SSF52172 556 672 5.55E-23 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 Pfam PF12833 Helix-turn-helix domain 150 228 6.8E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 Gene3D G3DSA:2.60.120.10 3 90 8.1E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 Gene3D G3DSA:1.10.10.60 95 182 2.8E-9 T 28-03-2018 SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 SMART SM00342 144 227 3.4E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 SUPERFAMILY SSF46689 181 229 1.12E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 SUPERFAMILY SSF46689 129 177 1.34E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09490 3d0cfe9dd3a360417f62e25ce0e78328 232 Gene3D G3DSA:1.10.10.60 183 231 2.3E-12 T 28-03-2018 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 198 339 6.2E-66 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Gene3D G3DSA:3.30.230.40 257 357 5.8E-33 T 28-03-2018 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Gene3D G3DSA:3.30.230.40 169 255 1.9E-35 T 28-03-2018 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 228 241 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 SUPERFAMILY SSF54211 254 343 2.28E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Pfam PF08645 Polynucleotide kinase 3 phosphatase 4 128 5.0E-5 T 28-03-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 164 5.8E-71 T 28-03-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 147 2.1E-20 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 SUPERFAMILY SSF54211 169 253 1.14E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 143 4.4E-35 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 321 333 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Gene3D G3DSA:3.40.50.1000 2 154 1.7E-19 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 1 357 49.688 T 28-03-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 169 357 38.242 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SmaCSM2_RS09550 d914715499bba909620fa84deadd5b9a 357 SUPERFAMILY SSF56784 1 149 4.07E-33 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 SUPERFAMILY SSF56235 1 218 1.03E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 Gene3D G3DSA:3.60.20.10 1 237 3.3E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 PIRSF PIRSF001589 1 645 1.1E-157 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 570 2.9E-140 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 SUPERFAMILY SSF52402 490 630 2.71E-86 T 28-03-2018 SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 SUPERFAMILY SSF52402 253 403 2.71E-86 T 28-03-2018 SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 Pfam PF13537 Glutamine amidotransferase domain 52 171 6.6E-48 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 Pfam PF00733 Asparagine synthase 263 634 3.2E-109 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SmaCSM2_RS14175 dd024b06f23d246798bda0cca9c9d789 647 Gene3D G3DSA:3.40.50.620 238 642 3.7E-76 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS04635 3e9f142bddafbd57e3b351b29b8f71a9 245 Pfam PF12872 OST-HTH/LOTUS domain 173 236 6.2E-8 T 28-03-2018 IPR025605 OST-HTH/LOTUS domain SmaCSM2_RS04635 3e9f142bddafbd57e3b351b29b8f71a9 245 Gene3D G3DSA:3.40.50.1010 1 134 9.5E-24 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS04635 3e9f142bddafbd57e3b351b29b8f71a9 245 Pfam PF01936 NYN domain 5 128 1.8E-25 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type SmaCSM2_RS03135 66b9927b5137eedcfcf07870011d14fd 211 Gene3D G3DSA:2.40.160.20 8 210 2.8E-9 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS13180 7c677bba35c98998591d313dcef4c76d 96 SUPERFAMILY SSF54909 1 90 2.47E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS13180 7c677bba35c98998591d313dcef4c76d 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 3.3E-14 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SmaCSM2_RS13180 7c677bba35c98998591d313dcef4c76d 96 Gene3D G3DSA:3.30.70.100 1 90 9.3E-17 T 28-03-2018 SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 Gene3D G3DSA:1.10.357.10 1 209 2.9E-29 T 28-03-2018 SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 SUPERFAMILY SSF48498 84 194 2.08E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11245 52f3f71a5e509a2d800778977d07beb2 218 SUPERFAMILY SSF46689 2 77 8.74E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS15155 eb22586bb88daf556cf33675d3a3cbe8 175 Gene3D G3DSA:3.40.30.10 92 174 3.9E-12 T 28-03-2018 SmaCSM2_RS15155 eb22586bb88daf556cf33675d3a3cbe8 175 SUPERFAMILY SSF52833 20 174 4.14E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS15155 eb22586bb88daf556cf33675d3a3cbe8 175 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 28 174 5.3E-47 T 28-03-2018 SmaCSM2_RS15155 eb22586bb88daf556cf33675d3a3cbe8 175 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 26 174 6.8E-60 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15155 eb22586bb88daf556cf33675d3a3cbe8 175 PIRSF PIRSF000216 3 175 1.1E-53 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS17220 b2287b2009b2d0722bd91af61f339452 101 SUPERFAMILY SSF47413 8 91 3.18E-20 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS17220 b2287b2009b2d0722bd91af61f339452 101 Gene3D G3DSA:1.10.260.40 3 83 1.7E-6 T 28-03-2018 SmaCSM2_RS17220 b2287b2009b2d0722bd91af61f339452 101 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 83 1.6E-27 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.40.50.720 9 132 2.9E-33 T 28-03-2018 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SUPERFAMILY SSF55729 740 880 1.89E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.40.50.261 295 461 8.6E-40 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SUPERFAMILY SSF52210 298 455 4.45E-36 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.30.470.20 575 711 2.0E-31 T 28-03-2018 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Pfam PF13549 ATP-grasp domain 483 707 4.6E-73 T 28-03-2018 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SUPERFAMILY SSF56059 491 707 6.48E-29 T 28-03-2018 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Pfam PF13302 Acetyltransferase (GNAT) domain 742 879 4.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Pfam PF13380 CoA binding domain 14 135 3.2E-21 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.40.630.30 733 898 1.5E-22 T 28-03-2018 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SUPERFAMILY SSF51735 1 139 3.71E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.30.1490.20 511 574 6.9E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 289 6.3E-46 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SUPERFAMILY SSF52210 131 292 1.02E-34 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 Gene3D G3DSA:3.40.50.261 133 294 2.9E-33 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS21025 bb800b67c0748b06d3d7525a31a353f6 908 SMART SM00881 9 104 5.3E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SmaCSM2_RS11135 db1828331fb20bbf7a5d03ec349b7e64 251 Gene3D G3DSA:1.25.40.10 12 169 7.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS11135 db1828331fb20bbf7a5d03ec349b7e64 251 SUPERFAMILY SSF48452 91 210 1.68E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS11135 db1828331fb20bbf7a5d03ec349b7e64 251 PIRSF PIRSF030959 1 251 5.1E-76 T 28-03-2018 IPR014562 Uncharacterised conserved protein UCP030959, divergent TPR repeat-containing SmaCSM2_RS11135 db1828331fb20bbf7a5d03ec349b7e64 251 Gene3D G3DSA:1.25.40.10 170 243 0.31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 274 315 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 SUPERFAMILY SSF46689 222 271 6.81E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 Gene3D G3DSA:1.10.10.60 237 276 1.3E-8 T 28-03-2018 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 319 6.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 303 6.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 Gene3D G3DSA:1.10.10.60 277 328 1.5E-11 T 28-03-2018 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 Pfam PF01965 DJ-1/PfpI family 76 177 5.8E-9 T 28-03-2018 IPR002818 DJ-1/PfpI SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 Pfam PF12833 Helix-turn-helix domain 243 320 1.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 Gene3D G3DSA:3.40.50.880 5 236 1.4E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 SMART SM00342 237 319 8.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 SUPERFAMILY SSF46689 273 320 1.79E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13095 dcf20bb5f671d2426e05e2208a940c40 355 SUPERFAMILY SSF52317 11 199 2.71E-18 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS16330 0e77869d0a4f73cdf45d3be6a92dfeb2 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 210 1.1E-62 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 SmaCSM2_RS16330 0e77869d0a4f73cdf45d3be6a92dfeb2 212 Pfam PF03006 Haemolysin-III related 9 204 1.4E-37 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 2.0E-163 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 Gene3D G3DSA:2.40.50.140 32 123 3.5E-30 T 28-03-2018 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 Gene3D G3DSA:1.25.10.10 644 1074 1.4E-6 T 28-03-2018 IPR011989 Armadillo-like helical SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 SUPERFAMILY SSF50249 40 124 1.05E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 Hamap MF_00970 Ribonuclease E [rne]. 1 1042 34.861 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 Pfam PF00575 S1 RNA binding domain 36 117 5.2E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 Pfam PF10150 Ribonuclease E/G family 120 389 3.3E-96 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 SmaCSM2_RS14370 cf2a171e725c364a965144212e4d1792 1081 SMART SM00316 37 118 7.9E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 Gene3D G3DSA:2.40.10.10 70 131 4.3E-21 T 28-03-2018 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 SUPERFAMILY SSF50494 12 270 2.45E-71 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 SMART SM00020 31 266 1.2E-72 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 75 80 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 215 226 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 Gene3D G3DSA:2.40.10.10 132 273 2.1E-37 T 28-03-2018 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 Gene3D G3DSA:2.40.10.10 32 69 1.9E-20 T 28-03-2018 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 123 137 2.8E-17 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 214 226 2.8E-17 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 2.8E-17 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS00360 f9f5bc6834898575b7f4f729842148a3 273 Pfam PF00089 Trypsin 32 258 2.6E-53 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SmaCSM2_RS03525 e79cfba4a3c7900bf14d95f1adc061fd 295 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 139 151 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SmaCSM2_RS03525 e79cfba4a3c7900bf14d95f1adc061fd 295 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 281 19.033 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SmaCSM2_RS03525 e79cfba4a3c7900bf14d95f1adc061fd 295 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 279 1.0E-74 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SmaCSM2_RS03525 e79cfba4a3c7900bf14d95f1adc061fd 295 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 275 1.5E-74 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SmaCSM2_RS00385 67f713823fc75077ea713352f3957158 301 Pfam PF04381 Putative exonuclease, RdgC 1 296 2.2E-96 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 SmaCSM2_RS00385 67f713823fc75077ea713352f3957158 301 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 300 38.455 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 Gene3D G3DSA:3.90.180.10 1 155 1.2E-39 T 28-03-2018 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 SMART SM00829 13 334 1.6E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 Gene3D G3DSA:3.40.50.720 156 263 6.1E-20 T 28-03-2018 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 SUPERFAMILY SSF50129 1 139 1.31E-28 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 Pfam PF13602 Zinc-binding dehydrogenase 192 334 9.3E-18 T 28-03-2018 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 12 337 4.4E-121 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 96 7.2E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS04210 5bc789efa74e889c675efd2030384c2b 339 SUPERFAMILY SSF51735 115 286 1.91E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Pfam PF00364 Biotin-requiring enzyme 131 199 2.0E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Pfam PF00364 Biotin-requiring enzyme 9 77 1.0E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 SUPERFAMILY SSF52777 327 567 7.56E-84 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:2.40.50.100 99 187 6.7E-16 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 150 179 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:2.40.50.100 63 98 3.2E-5 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:3.30.559.10 326 567 2.8E-81 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:3.90.1170.30 188 237 0.0076 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:2.40.50.100 16 62 2.0E-12 T 28-03-2018 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 SUPERFAMILY SSF47005 261 302 3.27E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 338 566 1.9E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 SUPERFAMILY SSF51230 127 217 1.57E-22 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Gene3D G3DSA:4.10.320.10 260 307 5.6E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 105 567 6.6E-206 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 SUPERFAMILY SSF51230 3 97 2.22E-22 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS18740 4ccf83904231b10e95dd01839e725931 567 Pfam PF02817 e3 binding domain 264 298 2.3E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS04515 9543a2cac711c8cd6b6032557bb83d0f 249 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 10 243 37.924 T 28-03-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 SmaCSM2_RS04515 9543a2cac711c8cd6b6032557bb83d0f 249 Gene3D G3DSA:1.10.510.10 89 245 1.8E-14 T 28-03-2018 SmaCSM2_RS04515 9543a2cac711c8cd6b6032557bb83d0f 249 SUPERFAMILY SSF56112 41 202 8.5E-21 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS04515 9543a2cac711c8cd6b6032557bb83d0f 249 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 40 241 1.6E-63 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 SmaCSM2_RS08630 5ea31938cf25f3bd434fe3e9496b2e52 285 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 34 273 6.8E-11 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS08630 5ea31938cf25f3bd434fe3e9496b2e52 285 Gene3D G3DSA:3.60.10.10 31 285 1.6E-43 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS08630 5ea31938cf25f3bd434fe3e9496b2e52 285 SUPERFAMILY SSF56219 30 282 2.49E-39 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 331 4.0E-34 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 SUPERFAMILY SSF52540 22 254 2.22E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 1.4E-32 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Gene3D G3DSA:1.10.10.10 259 329 1.4E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 SMART SM00382 53 180 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Gene3D G3DSA:1.10.8.60 186 256 3.4E-32 T 28-03-2018 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 3.5E-145 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Gene3D G3DSA:3.40.50.300 20 183 5.2E-26 T 28-03-2018 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 237 1.3E-117 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 346 177.888 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16700 9027c65078fcdaa65d22905fb0234443 346 SUPERFAMILY SSF46785 259 331 1.16E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 Pfam PF00571 CBS domain 368 417 1.3E-4 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 SMART SM01091 431 510 1.4E-24 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 Pfam PF03741 Integral membrane protein TerC family 15 203 7.5E-49 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 Pfam PF03471 Transporter associated domain 433 509 4.9E-22 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 Gene3D G3DSA:3.10.580.10 279 427 1.8E-20 T 28-03-2018 SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 SUPERFAMILY SSF56176 430 510 1.2E-19 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 SMART SM00116 307 356 14.0 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 SMART SM00116 369 417 1.5 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 Gene3D G3DSA:3.30.465.10 428 510 3.1E-25 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS05585 8aba31ace589cfcc9a24c514f5154319 512 SUPERFAMILY SSF54631 285 419 4.25E-22 T 28-03-2018 SmaCSM2_RS21355 06fdfd97215f9b0810d0f286f57a9e47 199 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 88 182 7.7E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SmaCSM2_RS21355 06fdfd97215f9b0810d0f286f57a9e47 199 Gene3D G3DSA:3.90.470.20 29 98 2.6E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SmaCSM2_RS21355 06fdfd97215f9b0810d0f286f57a9e47 199 Gene3D G3DSA:3.90.470.20 99 196 7.6E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SmaCSM2_RS21355 06fdfd97215f9b0810d0f286f57a9e47 199 SUPERFAMILY SSF56214 87 197 1.31E-25 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 Gene3D G3DSA:3.20.20.140 231 534 6.0E-49 T 28-03-2018 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 Gene3D G3DSA:2.30.40.10 55 163 9.6E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 Pfam PF07969 Amidohydrolase family 99 574 5.0E-98 T 28-03-2018 IPR013108 Amidohydrolase 3 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 SUPERFAMILY SSF51338 49 111 2.46E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 SUPERFAMILY SSF51338 536 576 2.46E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 SUPERFAMILY SSF51556 243 537 2.17E-29 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS11820 a28393bdec64dddbca2a555d232b3687 579 SUPERFAMILY SSF51556 110 168 2.17E-29 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Gene3D G3DSA:3.60.21.10 132 411 7.8E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Gene3D G3DSA:2.60.40.10 424 525 0.04 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Gene3D G3DSA:2.60.40.1120 19 92 4.1E-4 T 28-03-2018 SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 SUPERFAMILY SSF56300 134 402 8.66E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Pfam PF16371 N terminal of Calcineurin-like phosphoesterase 41 100 5.6E-11 T 28-03-2018 IPR032285 Calcineurin-like phosphoesterase, N-terminal SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Pfam PF16370 C terminal of Calcineurin-like phosphoesterase 348 516 1.6E-38 T 28-03-2018 IPR032288 Calcineurin-like phosphoesterase, C-terminal SmaCSM2_RS09575 ef44aeb08cf814c30a6d7cb2c8cb0823 529 Pfam PF00149 Calcineurin-like phosphoesterase 176 328 1.3E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 SUPERFAMILY SSF54373 349 497 2.67E-48 T 28-03-2018 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 Pfam PF00732 GMC oxidoreductase 221 312 6.2E-11 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 Pfam PF05199 GMC oxidoreductase 425 548 1.2E-20 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 SUPERFAMILY SSF51905 496 557 7.25E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 SUPERFAMILY SSF51905 1 59 7.25E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 SUPERFAMILY SSF51905 96 339 7.25E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS05480 dcdc8402b6daecf92fa93fca1d3116ef 561 Gene3D G3DSA:3.50.50.60 1 560 6.1E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Gene3D G3DSA:2.60.40.10 464 548 0.0011 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 PIRSF PIRSF029644 11 547 4.4E-119 T 28-03-2018 IPR016930 Uncharacterised conserved protein UCP029644, LysM, PA4035 SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Pfam PF01476 LysM domain 50 96 7.8E-10 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Gene3D G3DSA:2.60.40.10 363 463 0.0071 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 SMART SM00257 49 96 0.0034 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Gene3D G3DSA:3.10.350.10 45 98 9.2E-11 T 28-03-2018 SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Gene3D G3DSA:2.60.40.10 291 362 0.048 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 Pfam PF04773 FecR protein 139 243 5.3E-13 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS15650 090829fc4b2ac69c10e5e5bf4a0c24ee 566 SUPERFAMILY SSF54106 49 96 2.35E-6 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 SUPERFAMILY SSF51182 24 191 2.16E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 Pfam PF12833 Helix-turn-helix domain 188 265 6.9E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 SUPERFAMILY SSF46689 219 263 3.05E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 Gene3D G3DSA:1.10.10.60 220 265 8.9E-9 T 28-03-2018 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 Gene3D G3DSA:1.10.10.60 176 219 2.4E-13 T 28-03-2018 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 233 248 3.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 248 264 3.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 Pfam PF02311 AraC-like ligand binding domain 33 150 6.8E-10 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 219 260 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 SMART SM00342 182 264 2.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS08760 3eee7f29175ae458f24be077d274069a 265 Gene3D G3DSA:2.60.120.10 13 175 3.7E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS02265 eea33f07213f908cc8b128323a8c5abb 136 Gene3D G3DSA:3.10.180.10 7 135 1.1E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS02265 eea33f07213f908cc8b128323a8c5abb 136 SUPERFAMILY SSF54593 6 131 1.24E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 Gene3D G3DSA:3.30.200.20 5 125 6.5E-31 T 28-03-2018 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 ProSitePatterns PS01058 SAICAR synthetase signature 2. 218 226 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 SUPERFAMILY SSF56104 7 307 1.9E-99 T 28-03-2018 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 20 305 6.9E-73 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 ProSitePatterns PS01057 SAICAR synthetase signature 1. 119 133 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 15 306 28.042 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 Pfam PF01259 SAICAR synthetase 19 281 3.3E-98 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19735 6b7b1f01158d8cebb2a05e9c55f7ce3a 310 Gene3D G3DSA:3.30.470.20 126 262 2.5E-55 T 28-03-2018 SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 Pfam PF00266 Aminotransferase class-V 5 347 3.4E-52 T 28-03-2018 IPR000192 Aminotransferase class V domain SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 PIRSF PIRSF000525 1 361 1.4E-144 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 Gene3D G3DSA:3.40.640.10 16 256 1.7E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 Gene3D G3DSA:3.90.1150.10 258 359 4.5E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 SUPERFAMILY SSF53383 1 359 2.64E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 360 1.5E-153 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SmaCSM2_RS13645 ed4ef6b247fcf991023c2dc0bcc30e3c 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 360 48.967 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 421 3.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 SMART SM00388 213 279 2.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 SUPERFAMILY SSF47384 197 275 1.28E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 Gene3D G3DSA:1.10.287.130 203 275 2.5E-11 T 28-03-2018 SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 Gene3D G3DSA:3.30.565.10 276 424 1.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 276 4.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 SMART SM00387 322 426 2.0E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16020 5fc0541aa3b478a356ecebddaca4ac8e 428 SUPERFAMILY SSF55874 281 423 6.94E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 PRINTS PR00603 Cytochrome C1 signature 214 229 3.6E-8 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 PRINTS PR00603 Cytochrome C1 signature 195 214 3.6E-8 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 PRINTS PR00603 Cytochrome C1 signature 48 67 3.6E-8 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 Pfam PF02167 Cytochrome C1 family 93 248 4.3E-17 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 Pfam PF02167 Cytochrome C1 family 40 82 1.6E-8 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 Gene3D G3DSA:1.10.760.10 32 214 7.4E-56 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 SUPERFAMILY SSF46626 31 213 2.58E-47 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS07145 c6cac63b98ea675742cdcedb7b10f391 249 Gene3D G3DSA:1.20.5.100 218 249 3.1E-16 T 28-03-2018 SmaCSM2_RS03190 b77b815df18af25a93d0f14fbc42fed8 131 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 15 126 1.6E-29 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 SmaCSM2_RS03190 b77b815df18af25a93d0f14fbc42fed8 131 Gene3D G3DSA:3.40.1350.10 20 131 1.4E-34 T 28-03-2018 SmaCSM2_RS03190 b77b815df18af25a93d0f14fbc42fed8 131 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 125 22.088 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 SmaCSM2_RS03190 b77b815df18af25a93d0f14fbc42fed8 131 SUPERFAMILY SSF52980 16 115 5.69E-16 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS03190 b77b815df18af25a93d0f14fbc42fed8 131 Pfam PF02021 Uncharacterised protein family UPF0102 22 111 5.5E-24 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Gene3D G3DSA:3.40.50.300 20 147 3.6E-21 T 28-03-2018 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SUPERFAMILY SSF47384 647 720 7.26E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Pfam PF00512 His Kinase A (phospho-acceptor) domain 653 719 9.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SUPERFAMILY SSF55874 710 877 6.16E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Gene3D G3DSA:3.30.565.10 724 885 3.9E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SUPERFAMILY SSF52540 11 221 4.79E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Gene3D G3DSA:1.10.287.130 637 716 5.6E-15 T 28-03-2018 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Pfam PF00582 Universal stress protein family 249 359 6.6E-6 T 28-03-2018 IPR006016 UspA GO:0006950 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Gene3D G3DSA:1.20.120.620 394 492 2.8E-19 T 28-03-2018 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Pfam PF13493 Domain of unknown function (DUF4118) 397 495 1.3E-19 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SMART SM00388 652 720 7.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 819 829 5.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 860 873 5.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 801 815 5.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 835 853 5.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SMART SM00387 764 876 7.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 SUPERFAMILY SSF52402 250 359 1.08E-11 T 28-03-2018 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 22 229 2.1E-94 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 769 874 1.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01635 fd86763f02c5676441f46b347d2b5aa1 886 Gene3D G3DSA:3.40.50.620 225 363 7.5E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 423 2.6E-17 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SUPERFAMILY SSF52172 9 125 5.41E-7 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Pfam PF00563 EAL domain 447 679 8.2E-54 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Gene3D G3DSA:3.40.50.2300 8 137 4.1E-8 T 28-03-2018 SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SUPERFAMILY SSF55785 133 251 8.03E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Pfam PF13426 PAS domain 161 241 4.2E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SMART SM00052 441 685 1.3E-29 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 241 7.9E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Gene3D G3DSA:3.30.70.270 263 431 3.1E-27 T 28-03-2018 SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Gene3D G3DSA:3.20.20.450 432 689 1.0E-59 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 Gene3D G3DSA:3.30.450.20 138 255 9.6E-13 T 28-03-2018 SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 422 2.6E-15 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SUPERFAMILY SSF141868 448 685 9.68E-51 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SMART SM00267 259 429 1.4E-8 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08855 e6ea5c9b1ddcc042c1aad08ccb57493c 689 SUPERFAMILY SSF55073 276 428 1.65E-21 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 PIRSF PIRSF001589 1 633 2.5E-111 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 Gene3D G3DSA:3.60.20.10 1 227 2.5E-37 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 Pfam PF00733 Asparagine synthase 255 625 1.2E-85 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 6 560 8.8E-97 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 SUPERFAMILY SSF52402 480 620 1.18E-72 T 28-03-2018 SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 SUPERFAMILY SSF52402 246 395 1.18E-72 T 28-03-2018 SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 SUPERFAMILY SSF56235 1 211 1.8E-42 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 Pfam PF13537 Glutamine amidotransferase domain 58 164 2.0E-28 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SmaCSM2_RS02580 8bc36d6f25391b4fcb8bdcf77453a24b 633 Gene3D G3DSA:3.40.50.620 228 631 2.0E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 Gene3D G3DSA:3.40.50.980 113 282 4.4E-21 T 28-03-2018 SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 Gene3D G3DSA:3.10.129.10 451 561 3.2E-19 T 28-03-2018 SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 Gene3D G3DSA:3.30.300.30 338 450 3.0E-16 T 28-03-2018 SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 SUPERFAMILY SSF54637 458 547 1.03E-12 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 Pfam PF00501 AMP-binding enzyme 122 302 8.2E-15 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS21120 2711ffb1576856dd367564a6f7900951 561 SUPERFAMILY SSF56801 15 447 6.28E-53 T 28-03-2018 SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 SMART SM00487 28 226 5.7E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 4 583 47.082 T 28-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 SUPERFAMILY SSF52540 78 364 4.39E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Pfam PF03880 DbpA RNA binding domain 511 581 2.9E-23 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Pfam PF00270 DEAD/DEAH box helicase 34 198 1.2E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Pfam PF00271 Helicase conserved C-terminal domain 235 343 1.4E-27 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Gene3D G3DSA:3.40.50.300 2 221 1.9E-60 T 28-03-2018 SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 157 165 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 SMART SM00490 262 343 1.5E-32 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS06440 bae404ca0a0efec235bb218bab8502d4 648 Gene3D G3DSA:3.40.50.300 222 378 7.3E-45 T 28-03-2018 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 165 189 7.0E-41 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 7.0E-41 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 7.0E-41 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 135 154 7.0E-41 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 495 4.5E-194 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15115 5d1246ed39e7a0a6eb0df45b1111a935 502 Pfam PF00361 Proton-conducting membrane transporter 129 427 2.5E-79 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SMART SM00060 200 277 2.5E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Gene3D G3DSA:2.60.40.10 201 285 1.4E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Pfam PF00041 Fibronectin type III domain 202 274 2.3E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Pfam PF00704 Glycosyl hydrolases family 18 298 684 4.0E-89 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SUPERFAMILY SSF49299 100 191 6.28E-6 T 28-03-2018 IPR000601 PKD domain SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SMART SM00636 297 684 7.0E-136 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Gene3D G3DSA:2.10.10.20 31 93 3.5E-7 T 28-03-2018 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Gene3D G3DSA:3.40.1850.10 127 200 3.8E-4 T 28-03-2018 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SUPERFAMILY SSF54556 592 655 6.87E-13 T 28-03-2018 IPR029070 Chitinase insertion domain SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SUPERFAMILY SSF49265 181 289 4.54E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SMART SM00495 46 91 1.0E-6 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 ProSitePatterns PS01095 Chitinases family 18 active site. 458 466 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Gene3D G3DSA:3.20.20.80 293 699 1.1E-95 T 28-03-2018 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 Gene3D G3DSA:2.40.50.70 94 126 1.6E-17 T 28-03-2018 SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SUPERFAMILY SSF51445 654 698 8.7E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS02930 bc2dc0a2a3febb691852b9c8eb66ec31 699 SUPERFAMILY SSF51445 295 590 8.7E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS00500 405857695d7133152a671bffd8f43190 373 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 8.2E-9 T 28-03-2018 IPR024163 Aerotolerance regulator, N-terminal SmaCSM2_RS00500 405857695d7133152a671bffd8f43190 373 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 78 1.2E-20 T 28-03-2018 IPR011933 Double transmembrane domain SmaCSM2_RS03785 01d334a2effe763c3d4ce2ccac8bfbab 191 Gene3D G3DSA:3.40.30.10 21 191 1.3E-28 T 28-03-2018 SmaCSM2_RS03785 01d334a2effe763c3d4ce2ccac8bfbab 191 SUPERFAMILY SSF52833 8 23 1.88E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03785 01d334a2effe763c3d4ce2ccac8bfbab 191 SUPERFAMILY SSF52833 59 188 1.88E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03785 01d334a2effe763c3d4ce2ccac8bfbab 191 ProSitePatterns PS00194 Thioredoxin family active site. 84 102 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS03785 01d334a2effe763c3d4ce2ccac8bfbab 191 Pfam PF00578 AhpC/TSA family 59 174 5.7E-17 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 Gene3D G3DSA:3.40.190.10 177 259 6.1E-16 T 28-03-2018 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 Gene3D G3DSA:1.10.10.10 6 88 3.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 SUPERFAMILY SSF46785 8 85 9.33E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 Pfam PF03466 LysR substrate binding domain 95 292 2.6E-35 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 SUPERFAMILY SSF53850 95 296 5.57E-35 T 28-03-2018 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 Gene3D G3DSA:3.40.190.10 91 176 1.1E-14 T 28-03-2018 SmaCSM2_RS06525 dca79bc3ea7e68ad6021d5f5fe8b223c 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00390 2ba25fe72dea07ba2a520f1ee42ec634 259 Pfam PF01863 Protein of unknown function DUF45 42 243 2.1E-46 T 28-03-2018 IPR002725 Protein of unknown function DUF45 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 SUPERFAMILY SSF50249 1 103 4.29E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 SUPERFAMILY SSF55261 289 415 1.68E-41 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Pfam PF02938 GAD domain 306 400 3.2E-25 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 SUPERFAMILY SSF55681 110 290 5.57E-106 T 28-03-2018 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 SUPERFAMILY SSF55681 419 580 5.57E-106 T 28-03-2018 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Gene3D G3DSA:3.30.930.10 363 581 3.5E-55 T 28-03-2018 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Gene3D G3DSA:3.30.930.10 129 342 4.9E-53 T 28-03-2018 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 578 9.6E-231 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Pfam PF01336 OB-fold nucleic acid binding domain 18 100 1.4E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 579 32.879 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 6.1E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 6.1E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 218 6.1E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 188 200 6.1E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Gene3D G3DSA:2.40.50.140 1 106 1.6E-23 T 28-03-2018 SmaCSM2_RS16740 fe7f259fb6f36ffaafaec3cdc69ced98 583 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 553 6.8E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 Pfam PF07475 HPr Serine kinase C-terminal domain 135 306 1.0E-56 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 Gene3D G3DSA:3.40.1390.20 4 137 1.5E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 4 314 35.711 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 Gene3D G3DSA:3.40.50.300 138 298 8.7E-40 T 28-03-2018 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 SUPERFAMILY SSF75138 10 136 1.02E-28 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 309 5.0E-99 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 Pfam PF02603 HPr Serine kinase N terminus 5 132 2.2E-24 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SmaCSM2_RS05085 293bf0453c3bc3c52bb02ceb33f75111 316 SUPERFAMILY SSF53795 137 306 5.49E-33 T 28-03-2018 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 SUPERFAMILY SSF48498 108 212 5.78E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 110 211 9.9E-8 T 28-03-2018 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 Gene3D G3DSA:1.10.10.60 1 70 3.3E-19 T 28-03-2018 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 SUPERFAMILY SSF46689 16 88 1.05E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11650 49a3659ca6506a8601d540c2a9852e95 214 Gene3D G3DSA:1.10.357.10 71 214 2.5E-9 T 28-03-2018 SmaCSM2_RS13040 6ea7e35b48ac1855b9c14f67bb48fac0 308 Pfam PF04773 FecR protein 96 187 4.4E-19 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS13040 6ea7e35b48ac1855b9c14f67bb48fac0 308 PIRSF PIRSF018266 1 301 2.7E-56 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS15720 e88252720e60a298e807366081fb87c7 115 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 90 108 - T 28-03-2018 IPR019897 RidA, conserved site SmaCSM2_RS15720 e88252720e60a298e807366081fb87c7 115 Gene3D G3DSA:3.30.1330.40 1 115 1.6E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS15720 e88252720e60a298e807366081fb87c7 115 Pfam PF01042 Endoribonuclease L-PSP 12 113 8.6E-24 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SmaCSM2_RS15720 e88252720e60a298e807366081fb87c7 115 SUPERFAMILY SSF55298 4 115 1.24E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 SUPERFAMILY SSF53474 518 782 8.38E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 Pfam PF00326 Prolyl oligopeptidase family 579 783 3.1E-30 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 152 484 1.0E-30 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 Gene3D G3DSA:3.40.50.1820 502 786 9.4E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 SUPERFAMILY SSF82171 270 508 3.92E-24 T 28-03-2018 SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 SUPERFAMILY SSF82171 144 241 3.92E-24 T 28-03-2018 SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 SUPERFAMILY SSF82171 57 97 3.92E-24 T 28-03-2018 SmaCSM2_RS01545 cd14f395940d5635f0d94b85aa61cbdd 800 Gene3D G3DSA:2.140.10.30 37 501 1.8E-44 T 28-03-2018 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 Pfam PF04055 Radical SAM superfamily 18 177 2.0E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 SUPERFAMILY SSF102114 4 275 3.79E-69 T 28-03-2018 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 Pfam PF13353 4Fe-4S single cluster domain 20 102 1.0E-5 T 28-03-2018 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 Gene3D G3DSA:3.20.20.70 1 326 3.7E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 Pfam PF06463 Molybdenum Cofactor Synthesis C 184 309 1.6E-33 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 4 326 36.679 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 SMART SM00729 13 216 2.9E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 19 30 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SmaCSM2_RS12335 86a4350be3e33e7367cf4cde6f1f4f24 326 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 4 326 2.6E-98 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SmaCSM2_RS12285 c017f1dede3dc90f339820b843163167 226 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 9 160 9.6E-34 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 SmaCSM2_RS12285 c017f1dede3dc90f339820b843163167 226 Pfam PF02613 Nitrate reductase delta subunit 32 129 1.1E-10 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SmaCSM2_RS12285 c017f1dede3dc90f339820b843163167 226 SUPERFAMILY SSF89155 3 162 1.12E-31 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SmaCSM2_RS12285 c017f1dede3dc90f339820b843163167 226 Gene3D G3DSA:1.10.3480.10 1 209 1.4E-31 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 209.041 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 Pfam PF00709 Adenylosuccinate synthetase 5 422 4.0E-177 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 SUPERFAMILY SSF52540 4 429 9.03E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 Gene3D G3DSA:3.40.440.10 159 266 8.9E-24 T 28-03-2018 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 Gene3D G3DSA:3.40.440.10 1 158 1.5E-55 T 28-03-2018 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 SMART SM00788 4 424 9.4E-290 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 Gene3D G3DSA:3.90.170.10 267 430 1.8E-68 T 28-03-2018 SmaCSM2_RS16120 966a880776804e683065043f987aeb54 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 1.1E-176 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 SUPERFAMILY SSF55874 275 402 1.57E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 SUPERFAMILY SSF47384 196 240 1.45E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 402 9.9E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 Gene3D G3DSA:1.10.287.130 174 254 4.5E-6 T 28-03-2018 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 Gene3D G3DSA:3.30.565.10 263 404 8.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 381 8.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 8.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 400 8.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS08375 ec54a3e7f1f1ab35b70290d65b1db35e 408 SMART SM00387 299 403 6.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16015 11b217fb1387f792470fcc345b183254 416 Gene3D G3DSA:1.20.91.10 276 345 0.12 T 28-03-2018 SmaCSM2_RS16015 11b217fb1387f792470fcc345b183254 416 Pfam PF05684 Protein of unknown function (DUF819) 18 412 2.4E-117 T 28-03-2018 IPR008537 Protein of unknown function DUF819 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Gene3D G3DSA:1.10.460.10 478 610 1.1E-15 T 28-03-2018 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 SMART SM00436 122 217 1.4E-35 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 SUPERFAMILY SSF56712 1 602 3.14E-179 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 SMART SM00437 271 555 3.5E-63 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 SUPERFAMILY SSF57783 615 650 9.01E-10 T 28-03-2018 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Gene3D G3DSA:1.10.460.10 151 363 2.7E-40 T 28-03-2018 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 2.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 2.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 2.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 187 205 2.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 518 532 2.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 651 2.3E-9 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Pfam PF01131 DNA topoisomerase 152 586 1.5E-110 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 647 2.7E-220 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Gene3D G3DSA:3.40.50.140 1 150 1.4E-40 T 28-03-2018 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Pfam PF01751 Toprim domain 3 128 2.0E-16 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 323 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Gene3D G3DSA:3.30.65.10 611 659 2.0E-14 T 28-03-2018 SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 SMART SM00493 1 122 2.0E-25 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS07755 1acf7b83c7cd79279053b148e22beb9a 670 Gene3D G3DSA:2.70.20.10 364 477 7.4E-20 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 Gene3D G3DSA:1.10.530.10 254 378 1.7E-28 T 28-03-2018 SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 SUPERFAMILY SSF53955 71 376 4.12E-84 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 Gene3D G3DSA:1.10.8.350 66 131 9.7E-5 T 28-03-2018 SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 Gene3D G3DSA:1.10.8.350 132 248 1.1E-35 T 28-03-2018 SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 72 373 4.8E-117 T 28-03-2018 IPR011757 Lytic transglycosylase MltB SmaCSM2_RS18350 c24d1229f359625220369a2d0a2e94c4 381 Pfam PF13406 Transglycosylase SLT domain 70 371 1.7E-94 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 Gene3D G3DSA:2.30.30.30 2 92 2.3E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 SMART SM00739 4 31 4.3E-6 T 28-03-2018 IPR005824 KOW SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 Pfam PF00467 KOW motif 7 35 6.1E-6 T 28-03-2018 IPR005824 KOW SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 102 1.9E-32 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 4.0E-23 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 SUPERFAMILY SSF50104 3 99 3.36E-29 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS04045 961750bc0594f2b9ed746243ea6c6981 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 19.599 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 Gene3D G3DSA:3.40.50.300 4 208 2.9E-30 T 28-03-2018 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 SMART SM00490 278 360 6.6E-16 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 SMART SM00487 17 229 1.7E-21 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 Gene3D G3DSA:3.40.50.300 246 393 3.8E-21 T 28-03-2018 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 Pfam PF08494 DEAD/H associated 598 784 1.2E-42 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 Pfam PF00270 DEAD/DEAH box helicase 23 199 3.1E-22 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 Pfam PF00271 Helicase conserved C-terminal domain 258 356 8.5E-13 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 PIRSF PIRSF037307 3 810 1.1E-130 T 28-03-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 9 814 0.0 T 28-03-2018 IPR026362 DEXH box helicase, DNA ligase-associated SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 SUPERFAMILY SSF52540 31 201 1.84E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15870 ccb0bf9bf47518748e3c31b7e655391c 819 SUPERFAMILY SSF52540 232 366 1.84E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PRINTS PR01591 DNA-binding protein FIS signature 49 61 3.4E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PRINTS PR01591 DNA-binding protein FIS signature 18 34 3.4E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PRINTS PR01591 DNA-binding protein FIS signature 34 49 3.4E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 Pfam PF02954 Bacterial regulatory protein, Fis family 47 87 4.5E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PIRSF PIRSF002097 2 90 7.9E-34 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 SUPERFAMILY SSF46689 13 89 1.25E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 Gene3D G3DSA:1.10.10.60 4 90 5.9E-20 T 28-03-2018 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 70 90 2.0E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS19360 89dab68e15d609519832c43e8574dd21 91 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 53 70 2.0E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS16090 1ecbd0561e6cb3d2484a642f529f7056 233 Pfam PF12146 Serine aminopeptidase, S33 46 199 1.1E-6 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS16090 1ecbd0561e6cb3d2484a642f529f7056 233 Gene3D G3DSA:3.40.50.1820 6 231 1.6E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16090 1ecbd0561e6cb3d2484a642f529f7056 233 SUPERFAMILY SSF53474 7 229 2.58E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00100 b3321d48cf3aaaf13e3171b7f541b74c 157 SUPERFAMILY SSF56784 2 136 5.5E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS00100 b3321d48cf3aaaf13e3171b7f541b74c 157 Pfam PF03031 NLI interacting factor-like phosphatase 5 137 3.3E-8 T 28-03-2018 IPR004274 FCP1 homology domain SmaCSM2_RS00100 b3321d48cf3aaaf13e3171b7f541b74c 157 Gene3D G3DSA:3.40.50.1000 1 146 1.5E-5 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS13835 f042303b155b414c7e69f91b1791ecc0 362 Pfam PF07007 Lysozyme inhibitor LprI 61 148 1.5E-10 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 SUPERFAMILY SSF51338 423 461 5.18E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 Pfam PF01979 Amidohydrolase family 81 457 2.3E-16 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 Gene3D G3DSA:2.30.40.10 15 96 7.0E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 SUPERFAMILY SSF51338 21 85 7.41E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 SUPERFAMILY SSF51338 162 172 7.41E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 Gene3D G3DSA:3.20.20.140 97 416 1.1E-32 T 28-03-2018 SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 SUPERFAMILY SSF51556 280 421 7.26E-46 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS12840 3d4902f176fe2ded8f16337e41dae68e 485 SUPERFAMILY SSF51556 84 242 7.26E-46 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS05630 2363a2a97b39c4e1d1e20ddf9bf7ed8d 181 Gene3D G3DSA:3.40.30.10 27 180 1.4E-27 T 28-03-2018 SmaCSM2_RS05630 2363a2a97b39c4e1d1e20ddf9bf7ed8d 181 Pfam PF08534 Redoxin 54 174 1.0E-11 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SmaCSM2_RS05630 2363a2a97b39c4e1d1e20ddf9bf7ed8d 181 SUPERFAMILY SSF52833 49 178 1.1E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 Gene3D G3DSA:1.20.1250.20 241 432 2.9E-20 T 28-03-2018 SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 SUPERFAMILY SSF103473 23 426 5.62E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 Gene3D G3DSA:1.20.1250.20 18 240 9.7E-23 T 28-03-2018 SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 105 422 8.1E-107 T 28-03-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 26 423 1.8E-88 T 28-03-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 SmaCSM2_RS09645 33ada1a0032278d81af4701553508ea5 437 Pfam PF07690 Major Facilitator Superfamily 32 373 5.2E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 5 547 9.1E-292 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 Gene3D G3DSA:3.40.1080.10 17 216 4.6E-31 T 28-03-2018 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 4 547 9.8E-300 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 Gene3D G3DSA:3.40.1080.10 225 512 5.2E-38 T 28-03-2018 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 SUPERFAMILY SSF100950 34 273 1.36E-32 T 28-03-2018 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 SUPERFAMILY SSF100950 408 502 6.49E-22 T 28-03-2018 SmaCSM2_RS05705 a7de84e9b2ba18bf36cecfb3fad30940 547 SUPERFAMILY SSF100950 221 380 6.49E-22 T 28-03-2018 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 SUPERFAMILY SSF46609 1 90 1.7E-37 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 197 1.7E-38 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PIRSF PIRSF000349 1 203 5.8E-81 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 Gene3D G3DSA:1.10.287.990 20 89 1.4E-30 T 28-03-2018 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 SUPERFAMILY SSF54719 88 201 3.8E-44 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 9.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 9.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 9.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS14325 bb9988d1e6f3104d01d147bb7ca58df3 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 1.8E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS02455 850c9e5a0afaffea26efead8caa637f3 354 Gene3D G3DSA:3.40.50.150 26 134 0.0028 T 28-03-2018 SmaCSM2_RS02455 850c9e5a0afaffea26efead8caa637f3 354 Pfam PF05175 Methyltransferase small domain 178 346 6.7E-49 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SmaCSM2_RS02455 850c9e5a0afaffea26efead8caa637f3 354 SUPERFAMILY SSF53335 173 345 1.91E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02455 850c9e5a0afaffea26efead8caa637f3 354 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 278 284 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS02455 850c9e5a0afaffea26efead8caa637f3 354 Gene3D G3DSA:3.40.50.150 171 354 5.9E-30 T 28-03-2018 SmaCSM2_RS12245 31626e98fa222fd28650ef6fcb36818b 222 Pfam PF00005 ABC transporter 22 168 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS12245 31626e98fa222fd28650ef6fcb36818b 222 Gene3D G3DSA:3.40.50.300 6 222 9.9E-49 T 28-03-2018 SmaCSM2_RS12245 31626e98fa222fd28650ef6fcb36818b 222 SUPERFAMILY SSF52540 15 220 2.32E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS12245 31626e98fa222fd28650ef6fcb36818b 222 SMART SM00382 27 218 4.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 ProSitePatterns PS00217 Sugar transport proteins signature 2. 146 171 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 335 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 SUPERFAMILY SSF103473 34 447 5.36E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 Gene3D G3DSA:1.20.1250.20 245 454 4.2E-24 T 28-03-2018 SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 Pfam PF07690 Major Facilitator Superfamily 78 399 2.1E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS12000 a843cca4b8a8ada3603ce5cba9bfb015 495 Gene3D G3DSA:1.20.1250.20 30 244 2.1E-26 T 28-03-2018 SmaCSM2_RS12310 a0609a3805debed77d9da660ec79f140 180 SUPERFAMILY SSF53448 1 175 3.25E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS12310 a0609a3805debed77d9da660ec79f140 180 Pfam PF12804 MobA-like NTP transferase domain 5 145 5.2E-26 T 28-03-2018 IPR025877 MobA-like NTP transferase SmaCSM2_RS12310 a0609a3805debed77d9da660ec79f140 180 Gene3D G3DSA:3.90.550.10 1 172 1.1E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 Gene3D G3DSA:3.30.420.40 1 113 1.5E-14 T 28-03-2018 SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 Gene3D G3DSA:3.40.367.20 114 313 1.6E-29 T 28-03-2018 SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 Hamap MF_00524 Glucokinase [glk]. 7 326 33.538 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 SUPERFAMILY SSF53067 8 326 2.94E-62 T 28-03-2018 SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 TIGRFAM TIGR00749 glk: glucokinase 9 320 1.5E-82 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SmaCSM2_RS08410 57c886db019199e850b30b4b0b414d0f 335 Pfam PF02685 Glucokinase 9 324 5.0E-113 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 Pfam PF00929 Exonuclease 11 185 1.5E-27 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 Hamap MF_00157 Ribonuclease T [rnt]. 1 194 90.558 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 TIGRFAM TIGR01298 RNaseT: ribonuclease T 1 193 1.0E-101 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 SMART SM00479 9 194 1.2E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 SUPERFAMILY SSF53098 1 193 1.68E-51 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06850 51c94fc10502d19f0893b57b9bb6127e 194 Gene3D G3DSA:3.30.420.10 9 194 3.4E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS02935 e4dd1ff43eb50c1354806571a1b62f02 97 Pfam PF01527 Transposase 5 76 1.0E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS02935 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.20.5.10 68 89 4.5E-4 T 28-03-2018 SmaCSM2_RS02935 e4dd1ff43eb50c1354806571a1b62f02 97 SUPERFAMILY SSF46689 5 95 5.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS02935 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.10.10.10 1 67 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18795 e4dd1ff43eb50c1354806571a1b62f02 97 Pfam PF01527 Transposase 5 76 1.0E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS18795 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.20.5.10 68 89 4.5E-4 T 28-03-2018 SmaCSM2_RS18795 e4dd1ff43eb50c1354806571a1b62f02 97 SUPERFAMILY SSF46689 5 95 5.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18795 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.10.10.10 1 67 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10010 e4dd1ff43eb50c1354806571a1b62f02 97 Pfam PF01527 Transposase 5 76 1.0E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS10010 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.20.5.10 68 89 4.5E-4 T 28-03-2018 SmaCSM2_RS10010 e4dd1ff43eb50c1354806571a1b62f02 97 SUPERFAMILY SSF46689 5 95 5.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10010 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.10.10.10 1 67 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19530 e4dd1ff43eb50c1354806571a1b62f02 97 Pfam PF01527 Transposase 5 76 1.0E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS19530 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.20.5.10 68 89 4.5E-4 T 28-03-2018 SmaCSM2_RS19530 e4dd1ff43eb50c1354806571a1b62f02 97 SUPERFAMILY SSF46689 5 95 5.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS19530 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.10.10.10 1 67 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06845 e4dd1ff43eb50c1354806571a1b62f02 97 Pfam PF01527 Transposase 5 76 1.0E-11 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS06845 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.20.5.10 68 89 4.5E-4 T 28-03-2018 SmaCSM2_RS06845 e4dd1ff43eb50c1354806571a1b62f02 97 SUPERFAMILY SSF46689 5 95 5.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS06845 e4dd1ff43eb50c1354806571a1b62f02 97 Gene3D G3DSA:1.10.10.10 1 67 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Pfam PF00571 CBS domain 221 257 5.3E-4 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Pfam PF00571 CBS domain 139 194 0.0028 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 SUPERFAMILY SSF161093 280 451 7.85E-51 T 28-03-2018 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Pfam PF03448 MgtE intracellular N domain 37 137 8.3E-28 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Gene3D G3DSA:1.10.357.20 279 453 2.8E-37 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Gene3D G3DSA:3.10.580.10 127 270 5.6E-18 T 28-03-2018 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Gene3D G3DSA:1.25.60.10 4 126 1.2E-19 T 28-03-2018 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 SUPERFAMILY SSF158791 13 136 1.96E-30 T 28-03-2018 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 TIGRFAM TIGR00400 mgtE: magnesium transporter 21 451 9.3E-85 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 SUPERFAMILY SSF54631 139 277 1.19E-25 T 28-03-2018 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 Pfam PF01769 Divalent cation transporter 323 444 3.5E-29 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 SmaCSM2_RS05060 360723cacabea1a7c1a0466281eeb467 453 SMART SM00924 36 139 7.1E-38 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SmaCSM2_RS13050 3b9cb301e055dab306b5ffc93e9027b6 266 PIRSF PIRSF020419 4 266 7.8E-49 T 28-03-2018 IPR016773 Ferric uptake regulator, CjrA, predicted SmaCSM2_RS13050 3b9cb301e055dab306b5ffc93e9027b6 266 SUPERFAMILY SSF159501 24 263 9.94E-48 T 28-03-2018 SmaCSM2_RS13050 3b9cb301e055dab306b5ffc93e9027b6 266 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 43 234 1.1E-32 T 28-03-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 283 1.3E-15 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 3.5E-35 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 SUPERFAMILY SSF48179 165 287 2.38E-26 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 SUPERFAMILY SSF51735 1 163 4.8E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 Gene3D G3DSA:1.10.1040.10 162 289 9.5E-22 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 PIRSF PIRSF000103 1 292 7.2E-61 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SmaCSM2_RS11620 d3e620029753e149e1ed5b00a2ea9703 294 Gene3D G3DSA:3.40.50.720 3 161 4.5E-25 T 28-03-2018 SmaCSM2_RS17080 06806a68c80bf14f395accd8ae53ad49 330 Gene3D G3DSA:2.40.160.20 11 266 2.8E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 195 365 1.0E-29 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 TIGRFAM TIGR04511 SagB_rel_DH_2: putative peptide maturation dehydrogenase 3 378 3.6E-174 T 28-03-2018 IPR030965 Putative peptide maturation dehydrogenase SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 Pfam PF00881 Nitroreductase family 176 366 1.7E-20 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 Gene3D G3DSA:3.40.109.10 112 368 5.0E-36 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 SUPERFAMILY SSF55469 263 371 2.93E-18 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS01030 649e041f48673f9febe046f6037be6fe 388 SUPERFAMILY SSF55469 171 236 2.93E-18 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 Pfam PF00263 Bacterial type II and III secretion system protein 535 704 1.6E-45 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 PRINTS PR00811 Bacterial general secretion pathway protein D signature 691 705 1.7E-14 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 PRINTS PR00811 Bacterial general secretion pathway protein D signature 566 576 1.7E-14 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 PRINTS PR00811 Bacterial general secretion pathway protein D signature 531 555 1.7E-14 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 PRINTS PR00811 Bacterial general secretion pathway protein D signature 668 686 1.7E-14 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 PRINTS PR00811 Bacterial general secretion pathway protein D signature 457 467 1.7E-14 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 90 713 4.0E-168 T 28-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 649 682 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 Pfam PF03958 Bacterial type II/III secretion system short domain 251 318 7.8E-7 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS03010 f38ebd79fc839dd45008da1e43610010 733 Pfam PF03958 Bacterial type II/III secretion system short domain 325 457 5.3E-14 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 205 3.1E-39 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 SMART SM01007 18 206 4.8E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 Gene3D G3DSA:3.40.225.10 10 213 4.1E-43 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 SUPERFAMILY SSF53639 15 210 1.26E-43 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 213 110.15 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 SmaCSM2_RS09675 3d5f1e2b450964023e670c27eeb02d5a 213 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 20 211 2.0E-71 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 SmaCSM2_RS08570 c7048c4adc32b9c75947e80036273cf3 204 SUPERFAMILY SSF50324 39 204 2.88E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08570 c7048c4adc32b9c75947e80036273cf3 204 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 94 100 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08570 c7048c4adc32b9c75947e80036273cf3 204 Gene3D G3DSA:3.90.80.10 32 204 9.0E-48 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08570 c7048c4adc32b9c75947e80036273cf3 204 Pfam PF00719 Inorganic pyrophosphatase 49 202 1.9E-46 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08570 c7048c4adc32b9c75947e80036273cf3 204 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 44 203 30.663 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 PRINTS PR00171 Sugar transporter signature 377 398 3.4E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 PRINTS PR00171 Sugar transporter signature 113 132 3.4E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 PRINTS PR00171 Sugar transporter signature 281 291 3.4E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 PRINTS PR00171 Sugar transporter signature 400 412 3.4E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 PRINTS PR00171 Sugar transporter signature 30 40 3.4E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 SUPERFAMILY SSF103473 20 473 1.29E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 ProSitePatterns PS00216 Sugar transport proteins signature 1. 325 342 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 Gene3D G3DSA:1.20.1250.20 14 224 2.0E-33 T 28-03-2018 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 Pfam PF00083 Sugar (and other) transporter 24 473 8.0E-115 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 Gene3D G3DSA:1.20.1250.20 241 474 2.4E-35 T 28-03-2018 SmaCSM2_RS08325 ded6e83cb8a7d85dbc1f4dc6269f6fb8 474 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 12 472 3.9E-111 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 SUPERFAMILY SSF51419 8 233 1.13E-71 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 SMART SM01005 232 355 1.3E-49 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 SUPERFAMILY SSF50621 228 354 3.84E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 30 40 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 Gene3D G3DSA:3.20.20.10 10 200 1.6E-42 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 TIGRFAM TIGR00492 alr: alanine racemase 3 355 7.9E-102 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 Gene3D G3DSA:2.40.37.10 201 355 1.3E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 Pfam PF01168 Alanine racemase, N-terminal domain 8 218 1.1E-69 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 Hamap MF_01201 Alanine racemase. 1 355 33.145 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 8.8E-33 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 25 41 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 60 78 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 265 280 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 154 165 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 248 263 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 191 218 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 286 303 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS02430 50c213adbc04f70cb5d9d49cf4602ab1 355 PRINTS PR00992 Alanine racemase signature 120 132 1.0E-59 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.5E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 8.5E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.5E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 Gene3D G3DSA:1.10.1660.10 1 55 9.1E-24 T 28-03-2018 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 Pfam PF09278 MerR, DNA binding 45 108 4.5E-20 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 Gene3D G3DSA:1.10.1660.10 56 135 1.7E-24 T 28-03-2018 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 1.1E-51 T 28-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 SMART SM00422 1 70 6.1E-34 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 SUPERFAMILY SSF46955 1 126 5.13E-40 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS09615 5520fd1cd5f5e476b52f8ab39fe6b5ff 151 Pfam PF00376 MerR family regulatory protein 2 39 6.0E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 SUPERFAMILY SSF51905 8 375 5.3E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PIRSF PIRSF000350 1 451 1.9E-76 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 5.4E-31 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 5.4E-31 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 5.4E-31 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 5.4E-31 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 5.4E-31 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 343 451 5.0E-31 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 Gene3D G3DSA:3.50.50.60 2 165 7.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 Gene3D G3DSA:3.40.50.720 166 328 1.4E-30 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 Gene3D G3DSA:3.30.390.30 342 452 2.3E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 320 5.1E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 SUPERFAMILY SSF55424 340 452 3.09E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 446 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 339 360 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 1.1E-65 T 28-03-2018 SmaCSM2_RS15475 92daa05a584d7eb06b500d8740594f37 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 1.1E-65 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Gene3D G3DSA:1.25.60.10 3 115 1.1E-12 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Gene3D G3DSA:3.10.580.10 116 260 1.4E-20 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Pfam PF01769 Divalent cation transporter 314 444 5.3E-30 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 SUPERFAMILY SSF161093 272 451 1.44E-48 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 SMART SM00116 199 247 6.9E-11 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 SUPERFAMILY SSF158791 12 123 1.96E-18 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 SUPERFAMILY SSF54631 125 267 1.11E-26 T 28-03-2018 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Pfam PF03448 MgtE intracellular N domain 24 124 1.4E-18 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Gene3D G3DSA:1.10.357.20 270 454 1.3E-44 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 TIGRFAM TIGR00400 mgtE: magnesium transporter 20 452 6.7E-108 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 Pfam PF00571 CBS domain 196 247 1.3E-7 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS21030 08d0846474fe372d78e9e5a2028d3c9a 456 SMART SM00924 23 126 1.2E-19 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Gene3D G3DSA:3.40.50.620 1 627 3.1E-129 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Hamap MF_02004 Valine--tRNA ligase [valS]. 4 942 15.434 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 PRINTS PR00986 Valyl-tRNA synthetase signature 251 268 5.0E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 PRINTS PR00986 Valyl-tRNA synthetase signature 367 380 5.0E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 PRINTS PR00986 Valyl-tRNA synthetase signature 503 521 5.0E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 PRINTS PR00986 Valyl-tRNA synthetase signature 468 489 5.0E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 5.0E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 880 942 1.4E-12 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF52374 362 568 4.38E-131 T 28-03-2018 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF52374 2 194 4.38E-131 T 28-03-2018 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF52374 606 638 4.38E-131 T 28-03-2018 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Gene3D G3DSA:1.10.730.10 628 812 5.6E-50 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF47323 639 895 1.01E-60 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF50677 194 363 7.33E-57 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Pfam PF08264 Anticodon-binding domain of tRNA 669 818 5.2E-41 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 TIGRFAM TIGR00422 valS: valine--tRNA ligase 6 924 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 SUPERFAMILY SSF46589 880 942 8.89E-11 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 628 1.1E-198 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS02885 4a969a3eb6e2883291f0271b26020308 942 Gene3D G3DSA:1.10.287.380 873 941 2.4E-19 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Hamap MF_00203 UvrABC system protein C [uvrC]. 8 603 26.967 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SUPERFAMILY SSF46600 193 246 4.71E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 384 538 7.4E-48 T 28-03-2018 IPR001162 UvrC family homology region SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Pfam PF02151 UvrB/uvrC motif 207 240 7.9E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Pfam PF01541 GIY-YIG catalytic domain 23 97 5.5E-8 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SUPERFAMILY SSF82771 21 104 5.1E-19 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Gene3D G3DSA:3.40.1440.10 10 105 8.1E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SMART SM00465 21 102 1.5E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SUPERFAMILY SSF47781 521 605 4.77E-19 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SMART SM00278 552 571 1.2 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 SMART SM00278 584 603 180.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 16 584 3.9E-174 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Gene3D G3DSA:1.10.150.20 544 606 4.3E-12 T 28-03-2018 SmaCSM2_RS07340 628f0bc122928fe22c0c8596a4ea929d 614 Gene3D G3DSA:4.10.860.10 187 246 1.0E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 SMART SM01130 2 289 6.1E-110 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.4E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.4E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.4E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.4E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 Pfam PF00701 Dihydrodipicolinate synthetase family 3 281 1.5E-79 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 SUPERFAMILY SSF51569 3 284 2.83E-90 T 28-03-2018 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 278 3.3E-79 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 287 53.338 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 PIRSF PIRSF001365 2 295 1.2E-88 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS08310 40a2e87fdc237dbc1224758e141a40db 297 Gene3D G3DSA:3.20.20.70 1 297 1.0E-93 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 SUPERFAMILY SSF52922 192 325 4.45E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 Gene3D G3DSA:3.40.50.920 198 326 2.1E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 Pfam PF02779 Transketolase, pyrimidine binding domain 6 180 3.3E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 Gene3D G3DSA:3.40.50.970 2 197 9.0E-59 T 28-03-2018 SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 SUPERFAMILY SSF52518 5 193 4.37E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 Pfam PF02780 Transketolase, C-terminal domain 200 317 1.2E-38 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SmaCSM2_RS19830 c9fe4ba405c40effc3212af312a74929 328 SMART SM00861 6 181 1.9E-59 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 Gene3D G3DSA:1.10.1660.10 64 140 7.8E-20 T 28-03-2018 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 Gene3D G3DSA:1.10.1660.10 4 63 2.3E-19 T 28-03-2018 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 9 132 2.1E-54 T 28-03-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 Pfam PF00376 MerR family regulatory protein 9 46 5.1E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 1.3E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 1.3E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 1.3E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 SUPERFAMILY SSF46955 8 130 4.03E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 Pfam PF09278 MerR, DNA binding 51 113 2.1E-18 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 11 33 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10715 cb69a2546bf0366f32bb42836da28f35 144 SMART SM00422 8 77 7.4E-27 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 PIRSF PIRSF000005 2 248 1.1E-58 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 SUPERFAMILY SSF46626 52 133 7.56E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 Gene3D G3DSA:1.10.760.10 20 132 4.0E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 Gene3D G3DSA:1.10.760.10 142 246 1.7E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 Pfam PF00034 Cytochrome c 158 246 5.1E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 Pfam PF00034 Cytochrome c 55 133 1.9E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18110 94b1335dbedf6f068193a82cd140d1b4 266 SUPERFAMILY SSF46626 154 245 1.17E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS07605 de35ebe2cf2948e247317d676a2e6424 77 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 77 2.9E-32 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 SmaCSM2_RS07605 de35ebe2cf2948e247317d676a2e6424 77 Pfam PF11660 Protein of unknown function (DUF3262) 1 76 2.4E-26 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 SmaCSM2_RS17995 042cdf325780339e6cb039bb72a37d9c 470 Gene3D G3DSA:1.20.1600.10 22 470 1.1E-97 T 28-03-2018 SmaCSM2_RS17995 042cdf325780339e6cb039bb72a37d9c 470 Pfam PF02321 Outer membrane efflux protein 66 256 6.7E-28 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS17995 042cdf325780339e6cb039bb72a37d9c 470 Pfam PF02321 Outer membrane efflux protein 286 467 6.3E-29 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS17995 042cdf325780339e6cb039bb72a37d9c 470 SUPERFAMILY SSF56954 5 470 6.93E-108 T 28-03-2018 SmaCSM2_RS17995 042cdf325780339e6cb039bb72a37d9c 470 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 469 5.8E-111 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 7 693 3.0E-253 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 Gene3D G3DSA:3.40.720.10 125 445 5.0E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 Pfam PF05506 Domain of unknown function (DUF756) 599 673 9.9E-10 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 Pfam PF05506 Domain of unknown function (DUF756) 510 594 5.5E-18 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 Gene3D G3DSA:2.60.290.11 590 691 8.7E-4 T 28-03-2018 SmaCSM2_RS08205 fa74366ebfbdca1ea8857e407892b2f0 702 Pfam PF04185 Phosphoesterase family 44 440 9.4E-117 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 SUPERFAMILY SSF53335 14 289 3.49E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 PIRSF PIRSF037167 1 303 3.4E-125 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 Gene3D G3DSA:3.40.50.150 98 304 3.2E-31 T 28-03-2018 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 290 7.0E-116 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 287 3.7E-70 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 Gene3D G3DSA:1.10.8.10 11 97 1.3E-11 T 28-03-2018 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 200 206 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 Pfam PF05175 Methyltransferase small domain 132 213 1.3E-14 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SmaCSM2_RS15315 1c4393b743b7195558692b8424a3fb25 309 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 2 296 48.44 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Gene3D G3DSA:1.25.40.10 34 91 7.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Gene3D G3DSA:1.25.40.10 238 302 6.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Gene3D G3DSA:1.25.40.10 92 175 3.2E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Gene3D G3DSA:1.25.40.10 186 237 1.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Pfam PF13432 Tetratricopeptide repeat 79 145 0.0036 T 28-03-2018 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Pfam PF13432 Tetratricopeptide repeat 226 284 3.6E-4 T 28-03-2018 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 SUPERFAMILY SSF81901 44 279 2.22E-16 T 28-03-2018 SmaCSM2_RS09005 89fb9860748ab740515242add7adee1f 392 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 9 390 34.868 T 28-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 SmaCSM2_RS05495 a8a2fa41f68bb4d3f227dbd4721bd4ae 98 SUPERFAMILY SSF46626 4 97 4.44E-24 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS05495 a8a2fa41f68bb4d3f227dbd4721bd4ae 98 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 25 96 5.3E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS05495 a8a2fa41f68bb4d3f227dbd4721bd4ae 98 Gene3D G3DSA:1.10.760.10 12 98 4.5E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS06675 530cf041175ee9939831a4ee91207b57 249 Gene3D G3DSA:2.60.40.10 34 153 5.4E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS06675 530cf041175ee9939831a4ee91207b57 249 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 35 153 8.6E-21 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 SmaCSM2_RS06675 530cf041175ee9939831a4ee91207b57 249 SUPERFAMILY SSF49354 31 152 3.14E-23 T 28-03-2018 IPR008962 PapD-like SmaCSM2_RS14560 d058364e8cec1ceea27273ecba1e69e0 401 Gene3D G3DSA:1.20.1250.20 8 204 1.1E-17 T 28-03-2018 SmaCSM2_RS14560 d058364e8cec1ceea27273ecba1e69e0 401 SUPERFAMILY SSF103473 8 396 1.31E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS14560 d058364e8cec1ceea27273ecba1e69e0 401 Pfam PF07690 Major Facilitator Superfamily 23 359 1.5E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS14560 d058364e8cec1ceea27273ecba1e69e0 401 Gene3D G3DSA:1.20.1250.20 210 401 4.7E-12 T 28-03-2018 SmaCSM2_RS06970 a17194ea344713ef90a4aceadccf2814 428 Gene3D G3DSA:1.10.357.10 226 316 4.7E-6 T 28-03-2018 SmaCSM2_RS06970 a17194ea344713ef90a4aceadccf2814 428 Gene3D G3DSA:1.10.357.10 317 425 0.098 T 28-03-2018 SmaCSM2_RS06970 a17194ea344713ef90a4aceadccf2814 428 Pfam PF04286 Protein of unknown function (DUF445) 49 424 3.3E-106 T 28-03-2018 IPR007383 Protein of unknown function DUF445 SmaCSM2_RS11825 30629741d9d42398c549569e5b195eba 290 SUPERFAMILY SSF56281 33 252 1.02E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS11825 30629741d9d42398c549569e5b195eba 290 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 102 122 - T 28-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 SmaCSM2_RS11825 30629741d9d42398c549569e5b195eba 290 Pfam PF00753 Metallo-beta-lactamase superfamily 61 246 2.0E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS11825 30629741d9d42398c549569e5b195eba 290 SMART SM00849 58 246 1.3E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS11825 30629741d9d42398c549569e5b195eba 290 Gene3D G3DSA:3.60.15.10 22 290 4.0E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS10870 90b015e3fe018fa82cbffff3cbabcab4 184 Pfam PF13474 SnoaL-like domain 66 179 2.2E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SmaCSM2_RS10870 90b015e3fe018fa82cbffff3cbabcab4 184 SUPERFAMILY SSF54427 62 179 2.64E-23 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS10870 90b015e3fe018fa82cbffff3cbabcab4 184 Gene3D G3DSA:3.10.450.50 49 180 2.1E-20 T 28-03-2018 SmaCSM2_RS03705 641c18f040746f675c0b044d5baa5c6f 193 PIRSF PIRSF000232 1 192 1.3E-62 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like SmaCSM2_RS03705 641c18f040746f675c0b044d5baa5c6f 193 Pfam PF00881 Nitroreductase family 12 168 9.3E-21 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SmaCSM2_RS03705 641c18f040746f675c0b044d5baa5c6f 193 Gene3D G3DSA:3.40.109.10 6 190 7.1E-30 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS03705 641c18f040746f675c0b044d5baa5c6f 193 SUPERFAMILY SSF55469 9 187 2.75E-30 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SmaCSM2_RS00290 8cae0021c16cb57cb1d835a7f7081782 273 SMART SM00382 38 235 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS00290 8cae0021c16cb57cb1d835a7f7081782 273 SUPERFAMILY SSF52540 6 250 1.33E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00290 8cae0021c16cb57cb1d835a7f7081782 273 Gene3D G3DSA:3.40.50.300 3 256 4.3E-49 T 28-03-2018 SmaCSM2_RS00290 8cae0021c16cb57cb1d835a7f7081782 273 Pfam PF00005 ABC transporter 29 186 1.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 156 166 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 SUPERFAMILY SSF143975 3 420 2.48E-140 T 28-03-2018 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 4 602 1.1E-276 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 Pfam PF00920 Dehydratase family 68 599 4.6E-153 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS08400 e4693da937ea8300521f969dc8eb3a17 638 SUPERFAMILY SSF52016 421 601 2.82E-52 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 168 3.1E-28 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 280 3.2E-81 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 Pfam PF07650 KH domain 210 285 2.8E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 Gene3D G3DSA:3.40.50.300 11 178 2.9E-33 T 28-03-2018 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 1.5E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 61 76 1.5E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 SUPERFAMILY SSF52540 12 206 9.59E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 Gene3D G3DSA:3.30.300.20 187 298 8.1E-39 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 SUPERFAMILY SSF54814 183 298 3.01E-39 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 Pfam PF01926 50S ribosome-binding GTPase 12 126 9.1E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS15935 04fedddbcb7b7491c6cfd7d9cb60908e 298 Hamap MF_00367 GTPase Era [era]. 7 297 34.961 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS01450 2d9b6b285ac44cda3fd5aab5e76ff1b9 385 Pfam PF12704 MacB-like periplasmic core domain 23 229 6.0E-7 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS01450 2d9b6b285ac44cda3fd5aab5e76ff1b9 385 Pfam PF02687 FtsX-like permease family 290 376 4.6E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:3.30.70.1430 555 657 7.7E-14 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82693 267 324 1.18E-17 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82693 137 180 1.18E-17 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82693 45 125 3.09E-17 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82714 182 262 1.23E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 1.3E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1022 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:3.30.70.1430 42 135 2.3E-15 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82866 289 495 8.24E-37 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82714 712 795 1.96E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:1.20.1640.10 799 1020 1.3E-39 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:1.20.1640.10 282 503 2.2E-38 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82693 554 648 1.57E-5 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Pfam PF00873 AcrB/AcrD/AcrF family 6 1017 4.2E-269 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:3.30.2090.10 179 264 5.5E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 SUPERFAMILY SSF82866 797 1021 1.31E-52 T 28-03-2018 SmaCSM2_RS11945 ab7850850ec4951ec7a9b147eec2f706 1025 Gene3D G3DSA:3.30.2090.10 711 798 1.0E-23 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 Pfam PF08281 Sigma-70, region 4 110 161 6.4E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 Gene3D G3DSA:1.10.10.10 106 171 3.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 SUPERFAMILY SSF88659 102 165 1.0E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 Gene3D G3DSA:1.10.1740.10 3 75 5.4E-13 T 28-03-2018 SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 165 1.7E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 Pfam PF04542 Sigma-70 region 2 15 77 1.3E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08185 3dfd742c856c8c49a6b9e15680dd1d98 171 SUPERFAMILY SSF88946 7 92 3.37E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 306 3.8E-80 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 PIRSF PIRSF004491 4 313 1.7E-96 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 SMART SM00904 184 307 6.0E-63 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 Pfam PF06574 FAD synthetase 15 168 2.7E-46 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 Gene3D G3DSA:3.40.50.620 4 180 1.1E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 SUPERFAMILY SSF52374 18 177 7.88E-29 T 28-03-2018 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 SUPERFAMILY SSF82114 174 310 1.44E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 Pfam PF01687 Riboflavin kinase 185 306 1.8E-37 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SmaCSM2_RS05915 c9c4d52a31e1da0745a434fe516c9ffd 315 Gene3D G3DSA:2.40.30.30 181 315 8.2E-44 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 PIRSF PIRSF006305 1 190 2.5E-45 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 Pfam PF02545 Maf-like protein 2 185 1.2E-50 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 183 1.6E-47 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 Gene3D G3DSA:3.90.950.10 1 190 3.0E-61 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 Hamap MF_00528 Septum formation protein Maf [maf]. 1 190 29.391 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS15575 7d33aac40476c70804de322b8e964478 202 SUPERFAMILY SSF52972 1 184 1.05E-52 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 82 124 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 Pfam PF12833 Helix-turn-helix domain 51 129 8.5E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 Gene3D G3DSA:1.10.10.60 25 82 1.8E-14 T 28-03-2018 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 SMART SM00342 45 128 6.8E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 SUPERFAMILY SSF46689 81 128 1.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 SUPERFAMILY SSF46689 30 79 1.52E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12810 e14906eb215ce35787e0ac470f682d6b 147 Gene3D G3DSA:1.10.10.60 83 133 3.0E-15 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 Gene3D G3DSA:2.40.50.100 155 292 9.7E-7 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 Pfam PF13533 Biotin-lipoyl like 51 99 3.4E-16 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 SUPERFAMILY SSF111369 49 185 2.75E-24 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 Pfam PF13437 HlyD family secretion protein 160 240 5.2E-13 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 Gene3D G3DSA:2.40.50.100 124 154 0.12 T 28-03-2018 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 238 9.9E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS21595 0f7118c3820c4ff606a03c586faf7b7a 309 Gene3D G3DSA:2.40.50.100 50 123 7.7E-15 T 28-03-2018 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 PRINTS PR00721 Stomatin signature 119 140 1.9E-10 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 PRINTS PR00721 Stomatin signature 71 93 1.9E-10 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 PRINTS PR00721 Stomatin signature 200 218 1.9E-10 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 PRINTS PR00721 Stomatin signature 154 171 1.9E-10 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 SUPERFAMILY SSF117892 97 230 1.01E-20 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 TIGRFAM TIGR01933 hflK: HflK protein 66 323 9.8E-99 T 28-03-2018 IPR010201 HflK GO:0016021 SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 Pfam PF01145 SPFH domain / Band 7 family 69 240 1.9E-28 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS16135 93ec50f97caed27079a388a36abcbbec 377 SMART SM00244 64 224 4.3E-33 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS00080 3482b945a0889663b3818e7de65a2d19 74 Gene3D G3DSA:1.10.260.40 1 72 2.7E-17 T 28-03-2018 SmaCSM2_RS00080 3482b945a0889663b3818e7de65a2d19 74 Pfam PF01381 Helix-turn-helix 14 66 2.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS00080 3482b945a0889663b3818e7de65a2d19 74 SMART SM00530 13 68 4.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS00080 3482b945a0889663b3818e7de65a2d19 74 SUPERFAMILY SSF47413 8 70 5.36E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 SUPERFAMILY SSF47090 45 100 7.53E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 Pfam PF01471 Putative peptidoglycan binding domain 49 98 1.5E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 SUPERFAMILY SSF141523 185 317 2.62E-26 T 28-03-2018 SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 Gene3D G3DSA:2.40.440.10 180 320 8.5E-28 T 28-03-2018 SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 Pfam PF03734 L,D-transpeptidase catalytic domain 188 317 1.8E-18 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SmaCSM2_RS16105 cd39a01f23acd80cd69a16eeb1ce6cd2 320 Gene3D G3DSA:1.10.101.10 36 104 8.7E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS00510 cf27a940e32fb11697998d9fc9a09db1 327 Gene3D G3DSA:3.40.50.300 24 194 3.5E-27 T 28-03-2018 SmaCSM2_RS00510 cf27a940e32fb11697998d9fc9a09db1 327 SUPERFAMILY SSF52540 8 299 2.61E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00510 cf27a940e32fb11697998d9fc9a09db1 327 PIRSF PIRSF002849 2 327 1.5E-123 T 28-03-2018 SmaCSM2_RS00510 cf27a940e32fb11697998d9fc9a09db1 327 Gene3D G3DSA:1.10.8.300 207 323 7.3E-31 T 28-03-2018 SmaCSM2_RS00510 cf27a940e32fb11697998d9fc9a09db1 327 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 177 3.4E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 Gene3D G3DSA:3.40.190.10 180 267 2.4E-27 T 28-03-2018 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 SUPERFAMILY SSF46785 5 114 2.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 Pfam PF03466 LysR substrate binding domain 90 294 1.2E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.6E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 SUPERFAMILY SSF53850 92 297 4.89E-41 T 28-03-2018 SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 Gene3D G3DSA:1.10.10.10 3 88 3.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04995 f105cf68603a353288254413b82dd535 299 Gene3D G3DSA:3.40.190.10 89 179 1.6E-11 T 28-03-2018 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Gene3D G3DSA:3.40.50.2300 377 503 5.7E-11 T 28-03-2018 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SUPERFAMILY SSF47384 146 213 3.73E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SMART SM00448 386 498 0.04 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SMART SM00448 11 123 2.0E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SMART SM00388 151 216 6.2E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SUPERFAMILY SSF52172 11 140 1.99E-26 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 365 4.3E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 313 4.3E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 327 4.3E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 346 4.3E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 366 1.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SUPERFAMILY SSF55874 219 366 7.33E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Gene3D G3DSA:3.40.50.2300 4 135 3.4E-25 T 28-03-2018 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Gene3D G3DSA:3.30.565.10 217 376 2.7E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SMART SM00387 257 368 1.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 SUPERFAMILY SSF52172 384 502 4.41E-11 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Gene3D G3DSA:1.10.287.130 136 212 1.3E-6 T 28-03-2018 SmaCSM2_RS18275 45134fe0c9e0cbdbfd771f31ad539c6b 503 Pfam PF00072 Response regulator receiver domain 13 118 3.1E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06415 5e858a984235c21ef5a40059a7f389db 387 Gene3D G3DSA:3.90.226.10 97 271 1.6E-4 T 28-03-2018 SmaCSM2_RS06415 5e858a984235c21ef5a40059a7f389db 387 SUPERFAMILY SSF52096 117 270 9.84E-11 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS00955 6add8639a58c3e63732121408290578b 200 SMART SM00563 50 162 2.8E-20 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS00955 6add8639a58c3e63732121408290578b 200 SUPERFAMILY SSF69593 21 175 4.58E-17 T 28-03-2018 SmaCSM2_RS00955 6add8639a58c3e63732121408290578b 200 Gene3D G3DSA:3.40.1130.10 16 180 1.4E-19 T 28-03-2018 SmaCSM2_RS00955 6add8639a58c3e63732121408290578b 200 Pfam PF01553 Acyltransferase 50 156 9.0E-11 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS19000 5bb46b2227d5fc63362c2e7f85aa5039 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 4.7E-53 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SmaCSM2_RS19000 5bb46b2227d5fc63362c2e7f85aa5039 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 146 34.4 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SmaCSM2_RS19000 5bb46b2227d5fc63362c2e7f85aa5039 146 SUPERFAMILY SSF69500 1 144 7.06E-53 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SmaCSM2_RS19000 5bb46b2227d5fc63362c2e7f85aa5039 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 144 5.7E-54 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SmaCSM2_RS19000 5bb46b2227d5fc63362c2e7f85aa5039 146 Gene3D G3DSA:3.50.80.10 1 145 1.6E-53 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SmaCSM2_RS19555 3de93d89a837209f90de18ffa024a13e 725 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 10 717 3.1E-220 T 28-03-2018 IPR010020 Integral membrane protein, YccS/YhfK SmaCSM2_RS19555 3de93d89a837209f90de18ffa024a13e 725 Pfam PF12805 FUSC-like inner membrane protein yccS 69 355 1.7E-102 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal SmaCSM2_RS19555 3de93d89a837209f90de18ffa024a13e 725 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 11 715 1.7E-209 T 28-03-2018 IPR010019 Integral membrane protein, YccS SmaCSM2_RS19555 3de93d89a837209f90de18ffa024a13e 725 Pfam PF13515 Fusaric acid resistance protein-like 413 532 2.4E-20 T 28-03-2018 SmaCSM2_RS00050 2f9fb99683463e22f5793a85cf314efd 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 137 1.7E-25 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 PRINTS PR00207 Flagellin signature 111 134 2.7E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 PRINTS PR00207 Flagellin signature 76 95 2.7E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 PRINTS PR00207 Flagellin signature 37 54 2.7E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 143 7.5E-43 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 Gene3D G3DSA:1.20.1330.10 208 377 1.7E-27 T 28-03-2018 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 Gene3D G3DSA:1.20.1330.10 40 204 4.0E-46 T 28-03-2018 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 Pfam PF00700 Bacterial flagellin C-terminal helical region 319 404 4.6E-29 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10245 f0d70f577be3ba5532dbfd2b6425d26c 406 SUPERFAMILY SSF64518 1 405 5.23E-106 T 28-03-2018 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 SUPERFAMILY SSF51569 4 423 8.61E-158 T 28-03-2018 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 PIRSF PIRSF009264 1 428 1.4E-178 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 Gene3D G3DSA:3.20.20.70 4 293 2.5E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 Pfam PF08013 Tagatose 6 phosphate kinase 4 422 8.8E-190 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 Gene3D G3DSA:1.10.400.20 294 407 9.6E-46 T 28-03-2018 SmaCSM2_RS20595 963a39f62a7182c7f540605155db0766 444 TIGRFAM TIGR02810 agaZ_gatZ: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit 6 422 8.8E-184 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 SmaCSM2_RS11665 efa198c9b88c9bc1a89e269496923ca6 208 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 12 198 4.0E-55 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS11665 efa198c9b88c9bc1a89e269496923ca6 208 SUPERFAMILY SSF50486 10 202 9.42E-61 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SmaCSM2_RS11665 efa198c9b88c9bc1a89e269496923ca6 208 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 16 194 4.7E-61 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS11665 efa198c9b88c9bc1a89e269496923ca6 208 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 14 198 30.971 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS11665 efa198c9b88c9bc1a89e269496923ca6 208 Gene3D G3DSA:3.10.300.10 8 206 1.4E-67 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 SMART SM00382 26 214 2.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 Pfam PF00005 ABC transporter 18 164 1.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 234 2.9E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 2 239 9.1E-116 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 Gene3D G3DSA:3.40.50.300 1 234 1.6E-63 T 28-03-2018 SmaCSM2_RS05105 992688997a39aeee9333f3704d663a61 239 SUPERFAMILY SSF52540 2 234 1.59E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 SUPERFAMILY SSF56784 12 204 1.68E-35 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 16 178 4.0E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 Pfam PF13419 Haloacid dehalogenase-like hydrolase 69 178 7.5E-18 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 Gene3D G3DSA:3.40.50.1000 9 53 0.07 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 18 172 1.0E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS18390 b8958bc5ee0d062a3d6a92125a570ed9 207 Gene3D G3DSA:3.40.50.1000 56 204 6.3E-29 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS19570 a133e74250782cdd6d2d0ad893c24f73 95 Pfam PF04505 Interferon-induced transmembrane protein 14 78 3.5E-23 T 28-03-2018 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 6.2E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 5.0E-76 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 Gene3D G3DSA:3.40.1180.10 8 243 2.4E-88 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 40.31 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS06625 b249894bdcf4081cce2d41a2549c1fb7 255 SUPERFAMILY SSF64005 11 235 3.66E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 SUPERFAMILY SSF88659 162 235 5.61E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Gene3D G3DSA:1.10.10.10 91 141 5.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Pfam PF04542 Sigma-70 region 2 19 90 7.1E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Gene3D G3DSA:1.10.10.10 178 239 2.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 234 4.5E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 4 238 64.131 T 28-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 SUPERFAMILY SSF88659 91 157 1.18E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Gene3D G3DSA:1.10.1740.10 2 88 5.4E-22 T 28-03-2018 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Pfam PF04539 Sigma-70 region 3 102 169 3.7E-13 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 PIRSF PIRSF000770 3 241 1.3E-42 T 28-03-2018 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 PRINTS PR00046 Major sigma-70 factor signature 45 58 2.5E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 PRINTS PR00046 Major sigma-70 factor signature 188 200 2.5E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 PRINTS PR00046 Major sigma-70 factor signature 205 220 2.5E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 PRINTS PR00046 Major sigma-70 factor signature 220 231 2.5E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 SUPERFAMILY SSF88946 11 90 8.16E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 Pfam PF04545 Sigma-70, region 4 184 232 1.9E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10090 eb8c564686cace8c02664bae859bb726 247 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 19 236 6.0E-80 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Pfam PF01808 AICARFT/IMPCHase bienzyme 138 458 6.5E-113 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 8 527 44.194 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 9 527 1.4E-216 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 PIRSF PIRSF000414 3 527 2.3E-211 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Gene3D G3DSA:3.40.140.20 373 517 8.5E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 SUPERFAMILY SSF52335 8 197 1.83E-64 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Gene3D G3DSA:3.40.140.20 246 372 1.1E-50 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 SMART SM00798 138 459 1.0E-190 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Pfam PF02142 MGS-like domain 20 132 1.5E-24 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 Gene3D G3DSA:3.40.50.1380 1 197 6.9E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 SUPERFAMILY SSF53927 220 527 1.81E-126 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS19395 a031e062174fd5125b6c26962d205848 527 SMART SM00851 20 133 2.2E-52 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 104 227 1.0E-6 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SUPERFAMILY SSF52172 676 795 2.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Gene3D G3DSA:3.30.565.10 496 661 8.9E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SUPERFAMILY SSF47384 414 492 2.35E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Gene3D G3DSA:3.30.450.20 310 432 1.2E-14 T 28-03-2018 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Gene3D G3DSA:3.40.50.2300 673 801 3.0E-38 T 28-03-2018 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SMART SM00448 676 791 5.8E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Pfam PF00512 His Kinase A (phospho-acceptor) domain 429 492 5.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SMART SM00387 539 655 3.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Pfam PF00072 Response regulator receiver domain 678 791 1.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SUPERFAMILY SSF55874 485 653 2.23E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 633 2.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 652 2.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 594 2.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 540 653 1.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Gene3D G3DSA:1.10.287.130 433 490 8.0E-12 T 28-03-2018 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SUPERFAMILY SSF55785 327 408 5.86E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SUPERFAMILY SSF53850 28 228 9.93E-12 T 28-03-2018 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Gene3D G3DSA:3.40.190.10 111 202 7.6E-6 T 28-03-2018 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 SMART SM00388 429 494 2.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00400 43b520f3d79af2d6f07c1728081793d0 802 Pfam PF08447 PAS fold 322 396 1.8E-8 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 2.2E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 Pfam PF00072 Response regulator receiver domain 15 124 3.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 Gene3D G3DSA:1.10.10.10 130 237 2.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 SUPERFAMILY SSF52172 13 192 4.13E-40 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 SMART SM00862 159 235 8.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 Gene3D G3DSA:3.40.50.2300 6 129 6.9E-39 T 28-03-2018 SmaCSM2_RS01630 5a905a01e5d8fa22e1001621f042469d 237 SMART SM00448 13 123 9.8E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 149 2.6E-5 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 Pfam PF00593 TonB dependent receptor 238 703 1.1E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 42 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 Gene3D G3DSA:2.170.130.10 25 160 9.3E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 SUPERFAMILY SSF56935 23 706 5.09E-82 T 28-03-2018 SmaCSM2_RS04125 5cdd1c8ae39857fae1756a3913b5fce7 706 Gene3D G3DSA:2.40.170.20 161 706 4.2E-60 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 Gene3D G3DSA:3.40.190.10 179 262 1.6E-15 T 28-03-2018 SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 SUPERFAMILY SSF46785 1 112 2.73E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 SUPERFAMILY SSF53850 88 293 1.58E-35 T 28-03-2018 SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 Gene3D G3DSA:3.40.190.10 93 178 4.3E-20 T 28-03-2018 SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 Gene3D G3DSA:1.10.10.10 1 87 4.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS14135 759da55a7ebf1e72e8ed021340b1de98 299 Pfam PF03466 LysR substrate binding domain 91 290 1.3E-34 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 SUPERFAMILY SSF56954 1 428 2.49E-91 T 28-03-2018 SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 Gene3D G3DSA:1.20.1600.10 16 429 3.5E-77 T 28-03-2018 SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 PIRSF PIRSF001892 3 435 1.2E-58 T 28-03-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 Pfam PF02321 Outer membrane efflux protein 237 426 1.0E-35 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 Pfam PF02321 Outer membrane efflux protein 24 212 9.9E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS17815 afa5b3e4bb22efcf013392a53010597b 452 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 441 1.0E-121 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 7.9E-9 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 7.9E-9 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 7.9E-9 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 7.9E-9 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 Gene3D G3DSA:1.20.1250.20 4 202 5.9E-36 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 418 1.5E-74 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 SUPERFAMILY SSF103473 8 200 2.22E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 SUPERFAMILY SSF103473 248 460 2.22E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 Gene3D G3DSA:1.20.1250.20 259 469 8.5E-25 T 28-03-2018 SmaCSM2_RS16260 40decfa40cba69e59a88573a7b3fcbf5 469 Pfam PF07690 Major Facilitator Superfamily 19 410 4.6E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 Gene3D G3DSA:3.40.50.2300 7 132 4.7E-38 T 28-03-2018 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 SUPERFAMILY SSF46894 141 236 2.58E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 SUPERFAMILY SSF52172 5 133 2.28E-42 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 235 1.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 SMART SM00862 159 235 1.5E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 SMART SM00448 8 118 9.9E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 Gene3D G3DSA:1.10.10.10 133 240 5.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06825 e40e9efd69fc385041bfdd94c99ec89f 242 Pfam PF00072 Response regulator receiver domain 11 119 2.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03630 4dae1f659d433749f5606a825870ce50 87 Gene3D G3DSA:3.30.70.790 1 72 2.7E-16 T 28-03-2018 SmaCSM2_RS03630 4dae1f659d433749f5606a825870ce50 87 Pfam PF09413 Putative prokaryotic signal transducing protein 1 65 6.8E-12 T 28-03-2018 IPR018551 Domain of unknown function DUF2007 SmaCSM2_RS10360 e16473a7f2501aff9e2074882f04a320 396 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 165 310 7.5E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10360 e16473a7f2501aff9e2074882f04a320 396 SMART SM00283 89 354 1.7E-14 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10360 e16473a7f2501aff9e2074882f04a320 396 SUPERFAMILY SSF58104 50 335 1.7E-44 T 28-03-2018 SmaCSM2_RS10360 e16473a7f2501aff9e2074882f04a320 396 Gene3D G3DSA:1.10.287.950 89 316 2.0E-40 T 28-03-2018 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 SUPERFAMILY SSF52518 60 379 1.4E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 SMART SM00861 421 602 6.1E-29 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 SUPERFAMILY SSF52922 626 746 2.62E-22 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Pfam PF02780 Transketolase, C-terminal domain 635 737 3.3E-19 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Gene3D G3DSA:3.40.50.920 633 751 1.5E-18 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 SUPERFAMILY SSF52518 427 608 2.19E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Pfam PF00676 Dehydrogenase E1 component 69 373 2.4E-20 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Gene3D G3DSA:3.40.50.970 421 613 2.9E-34 T 28-03-2018 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Gene3D G3DSA:3.40.50.970 49 400 4.0E-41 T 28-03-2018 SmaCSM2_RS14180 99da3e8eb387e518dcbc0abee40487c4 759 Pfam PF02779 Transketolase, pyrimidine binding domain 427 594 1.2E-19 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 SMART SM00411 1 91 5.1E-41 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.3E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.3E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.3E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 Gene3D G3DSA:4.10.520.10 1 93 8.3E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 28.997 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 91 2.0E-42 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 SUPERFAMILY SSF47729 1 91 9.42E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SmaCSM2_RS08995 a559d4ca7fd76e2605d9a6e4e6c2ee39 101 Pfam PF00216 Bacterial DNA-binding protein 1 90 5.0E-28 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 SUPERFAMILY SSF51905 478 539 1.3E-87 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 SUPERFAMILY SSF51905 4 295 1.3E-87 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 86 109 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 5 558 60.679 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 Gene3D G3DSA:4.10.450.10 42 107 1.7E-25 T 28-03-2018 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 Pfam PF00732 GMC oxidoreductase 7 302 6.0E-97 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 261 275 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 TIGRFAM TIGR01810 betA: choline dehydrogenase 8 541 6.4E-279 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 PIRSF PIRSF000137 1 544 1.8E-143 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 Gene3D G3DSA:3.30.560.10 108 494 2.3E-100 T 28-03-2018 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 Pfam PF05199 GMC oxidoreductase 395 531 9.1E-40 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SmaCSM2_RS09925 29fb4d70a14602ce34621b173e600049 560 SUPERFAMILY SSF54373 297 479 1.37E-62 T 28-03-2018 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Gene3D G3DSA:1.10.730.10 612 830 1.5E-56 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 858 5.5E-268 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 240 263 8.8E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 544 557 8.8E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 577 586 8.8E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 52 63 8.8E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 419 434 8.8E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Gene3D G3DSA:3.30.2320.20 831 907 3.0E-17 T 28-03-2018 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 3 934 20.904 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 SUPERFAMILY SSF52374 5 203 1.54E-134 T 28-03-2018 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 SUPERFAMILY SSF52374 421 662 1.54E-134 T 28-03-2018 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Gene3D G3DSA:3.90.740.10 202 403 3.6E-42 T 28-03-2018 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 657 3.4E-192 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Pfam PF06827 Zinc finger found in FPG and IleRS 905 931 5.9E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 SUPERFAMILY SSF50677 205 421 1.27E-39 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Pfam PF08264 Anticodon-binding domain of tRNA 701 857 3.9E-23 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 SUPERFAMILY SSF47323 668 934 1.31E-68 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Gene3D G3DSA:3.40.50.620 404 611 1.1E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS05920 08534b2c55c828beaeb65895e0d82515 943 Gene3D G3DSA:3.40.50.620 30 201 3.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 199 0.0035 T 28-03-2018 SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 249 6.2E-44 T 28-03-2018 SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 Gene3D G3DSA:3.40.50.720 1 256 2.2E-55 T 28-03-2018 SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 SUPERFAMILY SSF51735 7 251 6.45E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 6.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09765 8cda20b1a97a5280290b97ff0e52adbc 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 52 501 1.1E-146 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Gene3D G3DSA:2.30.42.10 416 510 3.2E-12 T 28-03-2018 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Gene3D G3DSA:2.40.10.10 50 194 6.9E-39 T 28-03-2018 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 SUPERFAMILY SSF50494 50 290 4.89E-67 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Pfam PF13365 Trypsin-like peptidase domain 124 259 5.4E-36 T 28-03-2018 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Gene3D G3DSA:2.40.10.10 195 295 2.0E-38 T 28-03-2018 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 154 174 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 252 269 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 133 145 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 PRINTS PR00834 HtrA/DegQ protease family signature 194 218 1.1E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 SMART SM00228 418 498 1.4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 SMART SM00228 298 380 1.4E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 SUPERFAMILY SSF50156 256 381 4.99E-24 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 SUPERFAMILY SSF50156 417 499 5.13E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Gene3D G3DSA:2.30.42.10 296 401 1.2E-25 T 28-03-2018 SmaCSM2_RS15960 10291fc8f482f93b5de186a0e6251f22 511 Pfam PF13180 PDZ domain 299 389 1.2E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS05690 6e3352247983ca8d862a6b2ca5bbcae6 236 Gene3D G3DSA:3.90.226.10 4 207 1.6E-17 T 28-03-2018 SmaCSM2_RS05690 6e3352247983ca8d862a6b2ca5bbcae6 236 SUPERFAMILY SSF52096 18 207 5.33E-20 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS05690 6e3352247983ca8d862a6b2ca5bbcae6 236 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 7 231 1.1E-82 T 28-03-2018 SmaCSM2_RS05690 6e3352247983ca8d862a6b2ca5bbcae6 236 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 6 232 3.0E-77 T 28-03-2018 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 Gene3D G3DSA:2.40.170.20 185 930 9.5E-72 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 Gene3D G3DSA:2.170.130.10 40 184 3.2E-33 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 SUPERFAMILY SSF56935 419 479 1.54E-103 T 28-03-2018 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 SUPERFAMILY SSF56935 50 249 1.54E-103 T 28-03-2018 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 SUPERFAMILY SSF56935 333 381 1.54E-103 T 28-03-2018 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 SUPERFAMILY SSF56935 506 930 1.54E-103 T 28-03-2018 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 181 1.3E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15590 d9ba61e69771dd50179c1019d6c79877 931 Pfam PF00593 TonB dependent receptor 393 929 1.5E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03155 89a40e6ac5489a835b4c31cb2472d8a4 159 Pfam PF01029 NusB family 26 149 2.8E-31 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS03155 89a40e6ac5489a835b4c31cb2472d8a4 159 Gene3D G3DSA:1.10.940.10 21 156 6.1E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS03155 89a40e6ac5489a835b4c31cb2472d8a4 159 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 22 153 22.55 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 SmaCSM2_RS03155 89a40e6ac5489a835b4c31cb2472d8a4 159 SUPERFAMILY SSF48013 22 153 1.15E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SmaCSM2_RS03155 89a40e6ac5489a835b4c31cb2472d8a4 159 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 24 150 7.7E-41 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Pfam PF00668 Condensation domain 10 418 6.7E-31 T 28-03-2018 IPR001242 Condensation domain SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:3.40.50.980 597 748 1.3E-44 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Pfam PF13193 AMP-binding enzyme C-terminal domain 853 925 3.8E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SMART SM00824 Thioesterase 1049 1279 5.8E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SUPERFAMILY SSF52777 12 185 5.56E-30 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:3.30.300.30 839 936 1.6E-29 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:3.30.559.10 2 195 7.9E-25 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SUPERFAMILY SSF53474 1036 1283 1.67E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 ProSitePatterns PS00455 Putative AMP-binding domain signature. 591 602 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SUPERFAMILY SSF52777 188 442 1.67E-27 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SUPERFAMILY SSF56801 421 961 1.06E-152 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SUPERFAMILY SSF47336 942 1016 9.81E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Pfam PF00550 Phosphopantetheine attachment site 951 1015 6.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:3.40.50.1820 1029 1284 4.1E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 SMART SM00823 Phosphopantetheine attachment site 949 1019 0.0022 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:2.30.38.10 749 837 3.3E-24 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:3.40.50.980 447 596 2.7E-44 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Pfam PF00975 Thioesterase domain 1042 1251 1.0E-26 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Gene3D G3DSA:1.10.1200.10 937 1024 2.9E-20 T 28-03-2018 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 Pfam PF00501 AMP-binding enzyme 458 845 1.8E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS12490 f9034743be9a947e14c1b9453906ec93 1296 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 477 867 9.0E-135 T 28-03-2018 IPR010071 Amino acid adenylation domain SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 Gene3D G3DSA:3.40.190.10 183 268 2.7E-15 T 28-03-2018 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 Gene3D G3DSA:3.40.190.10 97 182 1.9E-16 T 28-03-2018 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 Gene3D G3DSA:1.10.10.10 1 85 7.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 SUPERFAMILY SSF46785 1 116 4.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 Pfam PF03466 LysR substrate binding domain 96 287 7.0E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS08920 8cdeb998dd5883c50dac4ac38ec75506 291 SUPERFAMILY SSF53850 97 288 3.26E-38 T 28-03-2018 SmaCSM2_RS08915 1376260573efe245a15ae74b4b769160 359 Pfam PF03601 Conserved hypothetical protein 698 23 336 1.3E-104 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SmaCSM2_RS08915 1376260573efe245a15ae74b4b769160 359 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 22 354 1.0E-110 T 28-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 SUPERFAMILY SSF46689 445 495 3.58E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 462 477 6.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 477 493 6.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Gene3D G3DSA:3.30.450.40 10 118 2.0E-4 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Gene3D G3DSA:3.40.50.300 127 278 9.4E-11 T 28-03-2018 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 SUPERFAMILY SSF46689 394 439 4.93E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 446 489 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 SUPERFAMILY SSF52540 128 344 3.8E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Gene3D G3DSA:1.10.8.60 279 348 2.5E-12 T 28-03-2018 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Gene3D G3DSA:1.10.10.60 391 443 1.1E-12 T 28-03-2018 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 SMART SM00342 409 493 1.1E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Gene3D G3DSA:1.10.10.60 444 498 7.0E-15 T 28-03-2018 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Pfam PF14532 Sigma-54 interaction domain 129 277 2.4E-22 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS11615 b8c8ee87f725a5eb36050909e3c765af 498 Pfam PF12833 Helix-turn-helix domain 415 494 1.0E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Gene3D G3DSA:3.30.70.240 610 678 6.4E-22 T 28-03-2018 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Pfam PF03764 Elongation factor G, domain IV 476 592 1.1E-33 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SUPERFAMILY SSF52540 6 282 1.04E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SUPERFAMILY SSF54211 476 593 6.07E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 50 65 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SUPERFAMILY SSF54980 403 478 3.09E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Pfam PF03144 Elongation factor Tu domain 2 321 387 8.1E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Gene3D G3DSA:3.30.70.870 393 488 2.0E-24 T 28-03-2018 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Gene3D G3DSA:2.40.30.10 275 391 7.4E-22 T 28-03-2018 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Gene3D G3DSA:3.30.230.10 489 609 4.2E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Hamap MF_00054_B Elongation factor G [fusA]. 5 678 79.903 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Pfam PF00679 Elongation factor G C-terminus 596 676 1.2E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SMART SM00889 477 594 2.6E-45 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SUPERFAMILY SSF54980 597 676 7.19E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SUPERFAMILY SSF50447 265 396 3.76E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Pfam PF00009 Elongation factor Tu GTP binding domain 8 282 1.1E-62 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 PRINTS PR00315 GTP-binding elongation factor signature 57 65 3.7E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.7E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.7E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.7E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.7E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 674 1.1E-222 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Gene3D G3DSA:3.40.50.300 1 274 1.7E-53 T 28-03-2018 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 SMART SM00838 596 678 1.7E-17 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 163 6.1E-28 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS10505 ca7d0639c9fe9370c8e4c9ced96119c8 678 Pfam PF14492 Elongation Factor G, domain II 404 474 8.5E-23 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 403 557 5.0E-48 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SMART SM00283 344 591 6.5E-82 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SMART SM00091 46 116 0.18 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SMART SM00091 170 238 0.05 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SUPERFAMILY SSF58104 310 592 4.1E-65 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 176 291 2.1E-15 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 55 165 7.0E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SUPERFAMILY SSF55785 180 282 1.52E-25 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Gene3D G3DSA:3.40.50.10600 40 162 1.4E-31 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Gene3D G3DSA:3.40.50.10600 163 286 3.2E-34 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SMART SM00086 243 285 2.8E-4 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SMART SM00086 121 163 3.6E-5 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Gene3D G3DSA:1.10.287.950 395 595 1.0E-48 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Gene3D G3DSA:1.10.287.950 287 394 1.4E-15 T 28-03-2018 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 SUPERFAMILY SSF55785 60 164 4.19E-24 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 519 548 1.1E-47 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 471 500 1.1E-47 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 469 1.1E-47 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 394 1.1E-47 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Pfam PF08447 PAS fold 71 156 1.1E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS13165 7877b8ad8052c2fcfa5f1195269b9e4c 608 Pfam PF08447 PAS fold 193 278 3.4E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS14300 08bcfd6b49dabfeb3c0c142c77901d24 100 Gene3D G3DSA:3.40.630.30 8 100 4.8E-19 T 28-03-2018 SmaCSM2_RS14300 08bcfd6b49dabfeb3c0c142c77901d24 100 Pfam PF14542 GCN5-related N-acetyl-transferase 21 97 4.2E-25 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase SmaCSM2_RS14300 08bcfd6b49dabfeb3c0c142c77901d24 100 SUPERFAMILY SSF55729 11 98 5.47E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS18890 fd6361297d0875729f19d4708717f4e1 172 SUPERFAMILY SSF102405 8 162 4.88E-23 T 28-03-2018 SmaCSM2_RS18890 fd6361297d0875729f19d4708717f4e1 172 Gene3D G3DSA:3.40.50.450 1 141 6.6E-21 T 28-03-2018 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SUPERFAMILY SSF46565 1 105 6.41E-34 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Gene3D G3DSA:2.60.260.20 198 249 3.6E-13 T 28-03-2018 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SUPERFAMILY SSF49493 254 339 6.02E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Pfam PF00226 DnaJ domain 5 67 5.0E-26 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Gene3D G3DSA:2.60.260.20 250 361 1.3E-27 T 28-03-2018 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Pfam PF00684 DnaJ central domain 143 202 5.4E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SMART SM00271 4 62 8.3E-30 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Gene3D G3DSA:1.10.287.110 1 113 2.6E-33 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SUPERFAMILY SSF57938 130 206 2.49E-20 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SUPERFAMILY SSF49493 195 255 2.75E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 SUPERFAMILY SSF49493 110 134 2.75E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 PRINTS PR00625 DnaJ domain signature 42 62 2.7E-29 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 PRINTS PR00625 DnaJ domain signature 7 25 2.7E-29 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 PRINTS PR00625 DnaJ domain signature 25 40 2.7E-29 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 PRINTS PR00625 DnaJ domain signature 62 81 2.7E-29 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 368 39.388 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Pfam PF01556 DnaJ C terminal domain 118 328 1.1E-40 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 Gene3D G3DSA:2.10.230.10 141 197 7.3E-16 T 28-03-2018 SmaCSM2_RS08755 ed1736705a3e4c9e8e1834fe54929ef7 374 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 344 1.6E-127 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SmaCSM2_RS21395 63a543c26e07de604161b1bd57667d42 191 Pfam PF02659 Putative manganese efflux pump 33 183 2.0E-51 T 28-03-2018 IPR003810 Putative manganese efflux pump SmaCSM2_RS21395 63a543c26e07de604161b1bd57667d42 191 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 186 25.477 T 28-03-2018 IPR022929 Putative manganese efflux pump MntP SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 SMART SM00490 461 547 2.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 Pfam PF12344 Ultra-violet resistance protein B 553 593 1.2E-17 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 Pfam PF04851 Type III restriction enzyme, res subunit 17 114 8.2E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 SMART SM00487 10 427 5.4E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 6 613 6.8E-273 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 SUPERFAMILY SSF52540 460 573 9.66E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 SUPERFAMILY SSF52540 40 83 9.66E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 Pfam PF00271 Helicase conserved C-terminal domain 435 546 7.1E-19 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 Gene3D G3DSA:3.40.50.300 12 413 2.8E-31 T 28-03-2018 SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 Gene3D G3DSA:3.40.50.300 416 590 8.1E-34 T 28-03-2018 SmaCSM2_RS07440 9d3e5b488d4b5fd4192912b708913e23 658 SUPERFAMILY SSF52540 6 416 2.8E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Pfam PF00326 Prolyl oligopeptidase family 482 691 1.3E-58 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Gene3D G3DSA:2.140.10.30 20 155 4.5E-18 T 28-03-2018 SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Gene3D G3DSA:2.140.10.30 168 408 6.4E-21 T 28-03-2018 SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 SUPERFAMILY SSF53474 435 690 3.3E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Gene3D G3DSA:3.40.50.1820 409 692 1.3E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Pfam PF07676 WD40-like Beta Propeller Repeat 281 299 0.05 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 Pfam PF07676 WD40-like Beta Propeller Repeat 91 113 0.27 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 SUPERFAMILY SSF69304 37 137 4.71E-30 T 28-03-2018 SmaCSM2_RS05750 d933fba37b8bdd03a691020c1a52d35c 692 SUPERFAMILY SSF69304 231 397 4.71E-30 T 28-03-2018 SmaCSM2_RS19970 3ec0bad24740aaaa87f05773f23fea13 400 Pfam PF07690 Major Facilitator Superfamily 20 247 9.3E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS19970 3ec0bad24740aaaa87f05773f23fea13 400 Gene3D G3DSA:1.20.1250.20 2 198 8.5E-18 T 28-03-2018 SmaCSM2_RS19970 3ec0bad24740aaaa87f05773f23fea13 400 Gene3D G3DSA:1.20.1250.20 204 400 5.2E-20 T 28-03-2018 SmaCSM2_RS19970 3ec0bad24740aaaa87f05773f23fea13 400 SUPERFAMILY SSF103473 8 394 3.27E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 SUPERFAMILY SSF48498 86 201 1.54E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 Gene3D G3DSA:1.10.10.60 1 67 3.8E-23 T 28-03-2018 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 201 1.2E-21 T 28-03-2018 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 6.6E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 Gene3D G3DSA:1.10.357.10 68 203 4.2E-23 T 28-03-2018 SmaCSM2_RS09305 83109e332fd9b92de556fb8d3ed777b8 203 SUPERFAMILY SSF46689 3 78 2.94E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 Pfam PF00106 short chain dehydrogenase 4 185 8.7E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 4.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 4.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 SUPERFAMILY SSF51735 4 217 7.7E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09315 4d5872cac9c59bcd74e04f8830b9b7a6 238 Gene3D G3DSA:3.40.50.720 2 231 4.6E-32 T 28-03-2018 SmaCSM2_RS10045 a6ebff49a9cad43c172d36c4f460d579 121 SUPERFAMILY SSF52172 3 121 4.27E-36 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10045 a6ebff49a9cad43c172d36c4f460d579 121 Gene3D G3DSA:3.40.50.2300 1 121 6.5E-36 T 28-03-2018 SmaCSM2_RS10045 a6ebff49a9cad43c172d36c4f460d579 121 Pfam PF00072 Response regulator receiver domain 5 116 1.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10045 a6ebff49a9cad43c172d36c4f460d579 121 SMART SM00448 3 116 7.1E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 485 3.1E-27 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 9.7E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 SUPERFAMILY SSF64484 16 945 0.0 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 SUPERFAMILY SSF64484 1134 1363 0.0 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1380 18.954 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Gene3D G3DSA:2.40.50.100 1154 1213 3.4E-12 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 8.9E-19 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Gene3D G3DSA:2.40.40.20 346 488 7.1E-40 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Gene3D G3DSA:2.40.50.100 908 1022 3.1E-30 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Gene3D G3DSA:2.40.50.100 1023 1127 7.7E-13 T 28-03-2018 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 2.1E-78 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1366 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF04997 RNA polymerase Rpb1, domain 1 17 342 4.5E-86 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 8.2E-29 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS03960 c4e1e7efd4ea6c36744e1be499af485b 1407 SMART SM00663 235 514 2.1E-183 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 Pfam PF07715 TonB-dependent Receptor Plug Domain 152 250 1.6E-8 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 SUPERFAMILY SSF56935 658 823 2.04E-65 T 28-03-2018 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 SUPERFAMILY SSF56935 157 622 2.04E-65 T 28-03-2018 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 Gene3D G3DSA:2.170.130.10 148 261 3.0E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 SMART SM00965 55 106 1.4E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 Pfam PF00593 TonB dependent receptor 313 821 1.5E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13045 e821276cd7e9a728a5d2933c1cb7c10c 823 Gene3D G3DSA:2.40.170.20 262 823 6.5E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 155 1.2E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 SUPERFAMILY SSF53155 5 79 2.16E-17 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 Gene3D G3DSA:3.30.160.70 1 71 1.1E-14 T 28-03-2018 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 Gene3D G3DSA:1.10.10.10 72 158 9.8E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 67 1.8E-4 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 156 3.3E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 156 41.767 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS06405 9d51cb153caa04dc759f86faabb40164 163 SUPERFAMILY SSF46767 75 156 2.35E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS14980 0b6e3fc270784b5b34f1209d07a857e5 140 Gene3D G3DSA:3.40.630.30 1 137 1.9E-22 T 28-03-2018 SmaCSM2_RS14980 0b6e3fc270784b5b34f1209d07a857e5 140 SUPERFAMILY SSF55729 1 136 3.01E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS14980 0b6e3fc270784b5b34f1209d07a857e5 140 Pfam PF00583 Acetyltransferase (GNAT) family 30 117 6.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.2E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 2.2E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 2.2E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 2.2E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.2E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 SUPERFAMILY SSF54719 82 191 7.59E-42 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 PIRSF PIRSF000349 1 192 1.2E-73 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 81 1.0E-23 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 SUPERFAMILY SSF46609 1 83 8.9E-28 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.6E-36 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SmaCSM2_RS07195 c62c59e21ec35e677b4b035732a87088 192 Gene3D G3DSA:1.10.287.990 20 82 1.8E-20 T 28-03-2018 SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 Gene3D G3DSA:3.40.190.10 89 175 1.3E-16 T 28-03-2018 SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 SUPERFAMILY SSF46785 4 83 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 Pfam PF03466 LysR substrate binding domain 89 291 2.0E-51 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 Gene3D G3DSA:1.10.10.10 2 84 6.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 SUPERFAMILY SSF53850 89 291 2.53E-52 T 28-03-2018 SmaCSM2_RS02355 c9dbb0d21f6893eaf525110fbb8db01b 293 Gene3D G3DSA:3.40.190.10 176 263 8.9E-30 T 28-03-2018 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 13 438 37.854 T 28-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 SUPERFAMILY SSF118215 20 413 1.03E-116 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 85 110 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 156 178 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 1.6E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 47 62 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 Pfam PF00375 Sodium:dicarboxylate symporter family 20 412 2.6E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 306 329 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site SmaCSM2_RS17870 df3f95a350e88510b1845b37c3d4c1a8 447 Gene3D G3DSA:1.10.3860.10 15 419 1.0E-113 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 SUPERFAMILY SSF55120 79 317 3.5E-81 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 137 151 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 SUPERFAMILY SSF55174 20 107 5.89E-7 T 28-03-2018 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 Pfam PF00849 RNA pseudouridylate synthase 94 244 2.3E-33 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 Pfam PF01479 S4 domain 21 67 1.5E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 Gene3D G3DSA:3.30.2350.10 85 318 8.5E-70 T 28-03-2018 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 Gene3D G3DSA:3.10.290.10 6 78 7.0E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS16880 165e0f77189d93c1183a5651ab910201 329 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 315 1.1E-95 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS09780 76d1e131609335f10d182e7753a51fa9 262 SUPERFAMILY SSF52096 2 258 9.96E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS09780 76d1e131609335f10d182e7753a51fa9 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 258 1.4E-49 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS09780 76d1e131609335f10d182e7753a51fa9 262 Gene3D G3DSA:1.10.12.10 218 260 1.9E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal SmaCSM2_RS09780 76d1e131609335f10d182e7753a51fa9 262 Gene3D G3DSA:3.90.226.10 4 217 8.8E-55 T 28-03-2018 SmaCSM2_RS12480 213e41fea02c62faf516b24ba68d4641 148 SMART SM01321 13 127 3.1E-29 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS12480 213e41fea02c62faf516b24ba68d4641 148 Gene3D G3DSA:3.30.70.1290 4 134 2.3E-27 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS12480 213e41fea02c62faf516b24ba68d4641 148 SUPERFAMILY SSF143422 6 133 3.01E-26 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS12480 213e41fea02c62faf516b24ba68d4641 148 Pfam PF01797 Transposase IS200 like 18 124 6.4E-13 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS09190 c70a70701ed4cbdf2045b9bdc66c981e 152 Gene3D G3DSA:3.30.530.20 3 142 2.3E-27 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS09190 c70a70701ed4cbdf2045b9bdc66c981e 152 SUPERFAMILY SSF55961 7 145 4.05E-34 T 28-03-2018 SmaCSM2_RS09190 c70a70701ed4cbdf2045b9bdc66c981e 152 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 140 1.1E-21 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 ProSitePatterns PS00079 Multicopper oxidases signature 1. 155 175 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 SUPERFAMILY SSF49503 184 392 1.82E-57 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 SUPERFAMILY SSF49503 458 604 3.39E-34 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Pfam PF07731 Multicopper oxidase 490 606 7.4E-26 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Gene3D G3DSA:2.60.40.420 186 386 6.1E-41 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 16 605 5.2E-298 T 28-03-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 ProSitePatterns PS00080 Multicopper oxidases signature 2. 588 599 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Pfam PF07732 Multicopper oxidase 71 180 6.4E-37 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 ProSitePatterns PS00079 Multicopper oxidases signature 1. 583 603 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Gene3D G3DSA:2.60.40.420 40 182 1.6E-29 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 SUPERFAMILY SSF49503 63 211 9.06E-40 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Pfam PF00394 Multicopper oxidase 190 367 4.0E-34 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SmaCSM2_RS16570 134951cd0afdfc297465df1c1a8c4cb5 607 Gene3D G3DSA:2.60.40.420 387 606 5.9E-49 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 SUPERFAMILY SSF56059 98 289 6.4E-45 T 28-03-2018 SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 292 49.746 T 28-03-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 Pfam PF08443 RimK-like ATP-grasp domain 98 285 1.5E-56 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 Gene3D G3DSA:3.30.470.20 170 277 5.2E-32 T 28-03-2018 SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 Gene3D G3DSA:3.30.1490.20 103 169 6.8E-8 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 3.7E-76 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 SmaCSM2_RS16985 81826b4076b79d895dfccf92af459109 292 Gene3D G3DSA:3.40.50.20 1 102 2.9E-35 T 28-03-2018 SmaCSM2_RS00580 b575e70ef409353dc985cc2d0890be6b 144 Pfam PF03061 Thioesterase superfamily 52 130 2.2E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SmaCSM2_RS00580 b575e70ef409353dc985cc2d0890be6b 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 137 6.2E-40 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SmaCSM2_RS00580 b575e70ef409353dc985cc2d0890be6b 144 SUPERFAMILY SSF54637 13 139 3.42E-31 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS00580 b575e70ef409353dc985cc2d0890be6b 144 Gene3D G3DSA:3.10.129.10 1 144 2.9E-27 T 28-03-2018 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 SMART SM00382 26 223 4.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 SMART SM00382 338 503 5.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Pfam PF16326 ABC transporter C-terminal domain 560 618 4.9E-9 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Gene3D G3DSA:3.40.50.300 278 540 9.7E-44 T 28-03-2018 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Pfam PF00005 ABC transporter 329 460 1.8E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Pfam PF00005 ABC transporter 17 178 9.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Pfam PF12848 ABC transporter 217 297 1.8E-23 T 28-03-2018 IPR032781 ABC-transporter extension domain SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Gene3D G3DSA:3.40.50.300 2 277 1.7E-52 T 28-03-2018 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 SUPERFAMILY SSF52540 301 515 2.13E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 SUPERFAMILY SSF52540 119 238 6.75E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 SUPERFAMILY SSF52540 2 81 6.75E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 Gene3D G3DSA:1.20.58.410 554 621 8.1E-4 T 28-03-2018 SmaCSM2_RS16775 4259f27fe34fdb1c411d36118e098451 621 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 8 768 8.2E-206 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 Gene3D G3DSA:1.20.1050.60 383 480 2.5E-31 T 28-03-2018 SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 Pfam PF07971 Glycosyl hydrolase family 92 282 763 2.2E-178 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 SUPERFAMILY SSF48208 302 749 9.01E-32 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 Gene3D G3DSA:2.70.98.10 35 360 9.4E-96 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS11970 6009f718cb4dba5123af2b9b93927094 783 Gene3D G3DSA:3.30.2080.10 612 777 2.7E-65 T 28-03-2018 SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 Gene3D G3DSA:1.20.1600.10 111 294 1.6E-25 T 28-03-2018 SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 Pfam PF00529 HlyD membrane-fusion protein of T1SS 97 343 8.4E-7 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 278 4.7E-29 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 54 358 1.1E-90 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 Gene3D G3DSA:2.40.50.100 46 110 1.2E-7 T 28-03-2018 SmaCSM2_RS08940 cd3946e4537d42e4c488af6f87a27dce 381 SUPERFAMILY SSF111369 73 284 3.01E-39 T 28-03-2018 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SUPERFAMILY SSF56037 200 394 8.89E-67 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SUPERFAMILY SSF55681 466 688 5.47E-48 T 28-03-2018 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Pfam PF03147 Ferredoxin-fold anticodon binding domain 699 792 4.1E-27 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Pfam PF01588 Putative tRNA binding domain 45 144 1.4E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Gene3D G3DSA:3.30.56.10 401 474 8.0E-24 T 28-03-2018 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SUPERFAMILY SSF54991 695 792 2.09E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SMART SM00896 699 792 8.1E-41 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 792 6.7E-226 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Gene3D G3DSA:3.30.70.380 696 792 2.8E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SMART SM00873 211 384 2.4E-81 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SMART SM00874 402 470 1.5E-29 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Gene3D G3DSA:3.30.56.10 1 187 2.0E-47 T 28-03-2018 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Gene3D G3DSA:3.30.930.10 490 688 6.9E-40 T 28-03-2018 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Gene3D G3DSA:3.50.40.10 196 395 7.6E-65 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Pfam PF03484 tRNA synthetase B5 domain 406 470 1.3E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SUPERFAMILY SSF46955 402 474 2.01E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 786 43.478 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 Pfam PF03483 B3/4 domain 212 384 3.0E-62 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SmaCSM2_RS15010 be9490dcd3bb719a6c0e0fb5cf381607 793 SUPERFAMILY SSF50249 37 188 7.1E-46 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS19475 0cbab03ad4169858bc9bdf31d03fe7bc 576 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 14 569 0.0 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 SmaCSM2_RS19475 0cbab03ad4169858bc9bdf31d03fe7bc 576 PIRSF PIRSF000719 6 576 1.8E-229 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 SmaCSM2_RS19475 0cbab03ad4169858bc9bdf31d03fe7bc 576 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 14 570 1.7E-207 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 SmaCSM2_RS19475 0cbab03ad4169858bc9bdf31d03fe7bc 576 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 6 576 37.735 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 SmaCSM2_RS11125 036b3e5417eba69ee59c0e8442107faa 186 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 105 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SmaCSM2_RS11125 036b3e5417eba69ee59c0e8442107faa 186 SUPERFAMILY SSF53927 1 144 8.38E-34 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS11125 036b3e5417eba69ee59c0e8442107faa 186 Gene3D G3DSA:3.40.140.10 1 169 9.1E-34 T 28-03-2018 SmaCSM2_RS11125 036b3e5417eba69ee59c0e8442107faa 186 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 116 1.4E-24 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SmaCSM2_RS17185 cccd6d44c31f38216bb674eaf07b4d34 272 SUPERFAMILY SSF48537 27 267 1.57E-59 T 28-03-2018 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 SmaCSM2_RS17185 cccd6d44c31f38216bb674eaf07b4d34 272 Pfam PF02265 S1/P1 Nuclease 27 269 1.4E-66 T 28-03-2018 IPR003154 S1/P1 nuclease GO:0003676|GO:0004519|GO:0006308 SmaCSM2_RS17185 cccd6d44c31f38216bb674eaf07b4d34 272 Gene3D G3DSA:1.10.575.10 27 272 5.4E-64 T 28-03-2018 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 SmaCSM2_RS18580 30369f63fd8a5d9e11010979294a8ff4 171 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 17 170 7.0E-47 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 SmaCSM2_RS18580 30369f63fd8a5d9e11010979294a8ff4 171 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 25 168 4.9E-24 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS18580 30369f63fd8a5d9e11010979294a8ff4 171 SUPERFAMILY SSF54593 22 170 1.11E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18580 30369f63fd8a5d9e11010979294a8ff4 171 Gene3D G3DSA:3.10.180.10 14 171 5.1E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18580 30369f63fd8a5d9e11010979294a8ff4 171 ProSitePatterns PS00935 Glyoxalase I signature 2. 112 128 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 Pfam PF16930 Putative porin 41 581 3.5E-211 T 28-03-2018 IPR032638 Putative bacterial porin SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 SUPERFAMILY SSF56935 481 551 1.17E-5 T 28-03-2018 SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 SUPERFAMILY SSF56935 177 298 1.17E-5 T 28-03-2018 SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 SUPERFAMILY SSF56935 325 372 1.17E-5 T 28-03-2018 SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 SUPERFAMILY SSF56935 411 445 1.17E-5 T 28-03-2018 SmaCSM2_RS12085 95c33a653254379f9dda74596e3031c4 581 Gene3D G3DSA:2.40.160.10 112 581 2.3E-34 T 28-03-2018 SmaCSM2_RS10155 2b1669e26f3274e4f9009c078bd81a20 392 PRINTS PR01007 Flagellar hook-length control protein signature 23 40 3.5E-11 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 SmaCSM2_RS10155 2b1669e26f3274e4f9009c078bd81a20 392 PRINTS PR01007 Flagellar hook-length control protein signature 302 317 3.5E-11 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 SmaCSM2_RS10155 2b1669e26f3274e4f9009c078bd81a20 392 PRINTS PR01007 Flagellar hook-length control protein signature 284 302 3.5E-11 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 SmaCSM2_RS10155 2b1669e26f3274e4f9009c078bd81a20 392 PRINTS PR01007 Flagellar hook-length control protein signature 317 340 3.5E-11 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 SmaCSM2_RS10155 2b1669e26f3274e4f9009c078bd81a20 392 Pfam PF02120 Flagellar hook-length control protein FliK 271 350 1.6E-21 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Gene3D G3DSA:3.40.50.300 221 351 5.8E-14 T 28-03-2018 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 413 426 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Pfam PF02881 SRP54-type protein, helical bundle domain 156 220 2.5E-11 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Gene3D G3DSA:1.20.120.140 162 220 1.7E-18 T 28-03-2018 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Gene3D G3DSA:1.20.120.140 352 442 9.5E-23 T 28-03-2018 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 SMART SM00962 239 440 3.2E-110 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 SMART SM00382 238 416 3.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 167 440 62.34 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 Pfam PF00448 SRP54-type protein, GTPase domain 239 439 8.5E-72 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 167 439 1.4E-100 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 SMART SM00963 145 224 6.8E-19 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS08490 9c45e4c6a5e580714ce7d48a0ec74d27 445 SUPERFAMILY SSF52540 190 438 3.1E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21715 f2f54ec65abf804bc30a1c1ffc501414 413 Gene3D G3DSA:3.20.20.140 28 412 8.9E-104 T 28-03-2018 SmaCSM2_RS21715 f2f54ec65abf804bc30a1c1ffc501414 413 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 37 403 2.4E-98 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SmaCSM2_RS21715 f2f54ec65abf804bc30a1c1ffc501414 413 SUPERFAMILY SSF51556 326 407 1.18E-82 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS21715 f2f54ec65abf804bc30a1c1ffc501414 413 SUPERFAMILY SSF51556 32 281 1.18E-82 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 SUPERFAMILY SSF52540 19 352 1.38E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 Pfam PF00437 Type II/IV secretion system protein 94 283 1.6E-34 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 18 358 3.2E-136 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 Gene3D G3DSA:3.40.50.300 129 287 1.1E-22 T 28-03-2018 SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 Gene3D G3DSA:3.40.50.300 288 361 1.9E-12 T 28-03-2018 SmaCSM2_RS04980 2637a5ae81caabf27876313cc01b609b 387 Gene3D G3DSA:3.30.450.90 15 113 2.1E-20 T 28-03-2018 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 SUPERFAMILY SSF51735 4 259 1.38E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 258 4.5E-55 T 28-03-2018 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 187 0.0081 T 28-03-2018 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 Gene3D G3DSA:3.40.50.720 40 260 1.2E-58 T 28-03-2018 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 Gene3D G3DSA:3.40.50.720 1 39 4.5E-8 T 28-03-2018 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS09165 fc0a39b208175f747efb7b8e07cac217 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 7.6E-101 T 28-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 TIGRFAM TIGR00012 L29: ribosomal protein uL29 6 57 2.0E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 Gene3D G3DSA:1.10.287.310 1 61 5.6E-20 T 28-03-2018 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 Pfam PF00831 Ribosomal L29 protein 4 57 4.8E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 SUPERFAMILY SSF46561 1 59 4.71E-19 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04030 73156137c7692a74880e7a9f747a491e 61 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 15.63 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 PRINTS PR00762 Chloride channel signature 351 371 1.1E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 PRINTS PR00762 Chloride channel signature 188 207 1.1E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 PRINTS PR00762 Chloride channel signature 386 402 1.1E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 SUPERFAMILY SSF54631 467 593 2.6E-11 T 28-03-2018 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 Gene3D G3DSA:1.10.3080.10 32 460 2.5E-57 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 Pfam PF00654 Voltage gated chloride channel 119 436 9.0E-53 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 Gene3D G3DSA:3.10.580.10 463 589 2.8E-9 T 28-03-2018 SmaCSM2_RS12670 4c26c4eb2afb9728ca95d2c235bef515 604 SUPERFAMILY SSF81340 31 457 6.41E-78 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SmaCSM2_RS20085 f74f00ccc1a33b6b6a1ae52888840ede 289 Gene3D G3DSA:3.60.15.10 3 289 2.5E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS20085 f74f00ccc1a33b6b6a1ae52888840ede 289 SUPERFAMILY SSF56281 12 255 2.17E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS20085 f74f00ccc1a33b6b6a1ae52888840ede 289 Pfam PF00753 Metallo-beta-lactamase superfamily 16 206 1.5E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS20085 f74f00ccc1a33b6b6a1ae52888840ede 289 SMART SM00849 16 206 1.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS09915 47245b67f3a283b63bdb3db947da6e80 290 SUPERFAMILY SSF52096 47 266 5.57E-35 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS09915 47245b67f3a283b63bdb3db947da6e80 290 Gene3D G3DSA:3.90.226.10 2 270 2.3E-39 T 28-03-2018 SmaCSM2_RS09915 47245b67f3a283b63bdb3db947da6e80 290 Pfam PF00378 Enoyl-CoA hydratase/isomerase 124 228 3.5E-20 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS18810 f1c6eb613db7cf4d2c02c00472d5c1df 219 Pfam PF02230 Phospholipase/Carboxylesterase 12 213 4.1E-47 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 SmaCSM2_RS18810 f1c6eb613db7cf4d2c02c00472d5c1df 219 SUPERFAMILY SSF53474 10 216 3.11E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18810 f1c6eb613db7cf4d2c02c00472d5c1df 219 Gene3D G3DSA:3.40.50.1820 2 216 4.4E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 Gene3D G3DSA:3.40.50.970 476 710 3.3E-60 T 28-03-2018 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 PIRSF PIRSF000156 1 895 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 SUPERFAMILY SSF52922 706 893 9.77E-60 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 139 294 2.5E-7 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 SUPERFAMILY SSF52518 60 471 3.68E-135 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 9 893 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 SUPERFAMILY SSF52518 479 704 1.91E-89 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 Gene3D G3DSA:3.40.50.920 711 895 4.0E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS02055 0124176b91c5924e3a57f8f27b4e90bc 895 Gene3D G3DSA:3.40.50.970 59 475 2.1E-81 T 28-03-2018 SmaCSM2_RS06865 07af9791374264a6d9369ad5941b55dc 291 Hamap MF_00697 UPF0276 protein . 22 290 44.597 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 SmaCSM2_RS06865 07af9791374264a6d9369ad5941b55dc 291 Pfam PF05114 Protein of unknown function (DUF692) 22 282 2.3E-100 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 SmaCSM2_RS06865 07af9791374264a6d9369ad5941b55dc 291 SUPERFAMILY SSF51658 30 226 3.52E-7 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS06865 07af9791374264a6d9369ad5941b55dc 291 Gene3D G3DSA:3.20.20.150 17 291 1.8E-79 T 28-03-2018 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 SMART SM00448 3 115 2.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 SMART SM00850 160 256 3.8E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 Pfam PF00072 Response regulator receiver domain 6 113 1.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 Gene3D G3DSA:3.40.50.2300 3 144 6.6E-32 T 28-03-2018 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 Pfam PF04397 LytTr DNA-binding domain 163 255 5.2E-21 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 SUPERFAMILY SSF52172 4 164 1.57E-33 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS02310 8bbf2037bd05962fe76769cba2bbb23d 256 Gene3D G3DSA:2.40.50.40 152 219 2.7E-16 T 28-03-2018 SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 PIRSF PIRSF002583 5 597 3.0E-98 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 PRINTS PR00775 90kDa heat shock protein signature 186 204 3.0E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 PRINTS PR00775 90kDa heat shock protein signature 168 185 3.0E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 PRINTS PR00775 90kDa heat shock protein signature 117 139 3.0E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 PRINTS PR00775 90kDa heat shock protein signature 33 55 3.0E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 168 5.1E-9 T 28-03-2018 SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 SUPERFAMILY SSF55874 12 206 6.65E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 SUPERFAMILY SSF54211 239 456 1.82E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 Gene3D G3DSA:3.30.565.10 36 212 2.0E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06030 8b51be5df20f7d10eaaa63f757009a34 619 Pfam PF00183 Hsp90 protein 252 356 3.7E-10 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 Gene3D G3DSA:1.10.287.890 204 291 3.1E-24 T 28-03-2018 SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 SUPERFAMILY SSF52540 5 73 2.32E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 SUPERFAMILY SSF52540 166 227 2.32E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 Gene3D G3DSA:3.40.50.300 5 194 5.8E-62 T 28-03-2018 SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 300 3.3E-91 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 Pfam PF01715 IPP transferase 43 292 6.0E-84 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 SUPERFAMILY SSF52540 10 155 6.35E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08115 d7d7b93566ce3206a78508c844e4ca2c 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 312 30.197 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 SUPERFAMILY SSF81593 799 901 2.28E-20 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:3.30.460.10 627 794 2.6E-51 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:3.30.460.10 109 280 2.6E-54 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Pfam PF08335 GlnD PII-uridylyltransferase 293 431 2.6E-42 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Pfam PF08335 GlnD PII-uridylyltransferase 810 893 3.2E-7 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 SUPERFAMILY SSF81301 516 794 2.09E-67 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 SUPERFAMILY SSF81593 283 432 1.41E-40 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:1.20.120.330 795 925 1.5E-22 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 SUPERFAMILY SSF81301 34 282 4.25E-68 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 544 788 2.1E-62 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 39 272 1.6E-60 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 34 931 17.856 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:1.10.4050.10 6 108 3.8E-5 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:1.10.4050.10 520 624 6.0E-10 T 28-03-2018 SmaCSM2_RS01990 8c7933d21929003669d643ad17a5fa31 931 Gene3D G3DSA:1.20.120.330 281 436 4.5E-45 T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 Gene3D G3DSA:3.40.50.2300 65 183 7.8E-31 T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 SMART SM00354 10 80 2.8E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 2.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 2.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 Pfam PF13377 Periplasmic binding protein-like domain 177 339 7.8E-37 T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 SUPERFAMILY SSF47413 11 69 2.65E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 Gene3D G3DSA:3.40.50.2300 184 323 5.1E-44 T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 SUPERFAMILY SSF53822 70 342 6.64E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 Gene3D G3DSA:1.10.260.40 11 64 5.3E-22 T 28-03-2018 SmaCSM2_RS14410 cfc274f5454c6ca8375b0b3db9d8cc3b 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 56 7.7E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09480 a3e05cf6f314860ceb63b3e7d9944d55 350 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 312 2.8E-45 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal SmaCSM2_RS09480 a3e05cf6f314860ceb63b3e7d9944d55 350 SUPERFAMILY SSF56235 26 319 2.39E-98 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS09480 a3e05cf6f314860ceb63b3e7d9944d55 350 Gene3D G3DSA:3.60.60.10 23 342 3.4E-101 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 SUPERFAMILY SSF55021 401 489 2.11E-22 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Pfam PF00742 Homoserine dehydrogenase 629 824 1.6E-50 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 SUPERFAMILY SSF51735 479 651 1.17E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Gene3D G3DSA:3.40.1160.10 17 304 3.5E-61 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Gene3D G3DSA:3.30.70.260 401 479 4.8E-20 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Gene3D G3DSA:3.30.360.10 651 807 3.8E-56 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 PIRSF PIRSF000727 20 831 0.0 T 28-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Pfam PF00696 Amino acid kinase family 20 300 5.8E-40 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 20 474 2.5E-106 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 SUPERFAMILY SSF55021 320 395 1.68E-18 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 ProSitePatterns PS00324 Aspartokinase signature. 22 30 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Gene3D G3DSA:3.40.50.720 480 650 1.5E-35 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 SUPERFAMILY SSF55347 629 811 4.64E-48 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 675 697 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 SUPERFAMILY SSF53633 21 313 4.68E-70 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Gene3D G3DSA:3.30.70.260 305 400 9.4E-20 T 28-03-2018 SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Pfam PF13840 ACT domain 407 469 2.8E-9 T 28-03-2018 IPR027795 GATS-like ACT domain SmaCSM2_RS09500 cc3dd64afffef50d8ad2fa1a5f3fc9e9 834 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 487 621 3.1E-22 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 Gene3D G3DSA:3.30.70.1230 14 208 2.6E-17 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 TIGRFAM TIGR04510 mod_pep_cyc: putative peptide modification system cyclase 14 823 0.0 T 28-03-2018 IPR030966 Putative peptide modification system cyclase SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 Gene3D G3DSA:1.25.40.10 497 618 5.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 Gene3D G3DSA:1.25.40.10 669 815 0.022 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 SUPERFAMILY SSF48452 411 602 5.18E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 SUPERFAMILY SSF55073 8 198 2.35E-20 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 Gene3D G3DSA:3.40.50.10070 254 386 2.2E-7 T 28-03-2018 SmaCSM2_RS01020 5732e87d35d15d4f8b154a4d5fc7635f 833 Gene3D G3DSA:1.25.40.10 400 493 2.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 SUPERFAMILY SSF142019 34 247 9.55E-45 T 28-03-2018 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 457 4.6E-15 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 SMART SM00928 337 382 5.4E-11 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 SUPERFAMILY SSF142984 250 332 1.57E-18 T 28-03-2018 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 Gene3D G3DSA:3.10.560.10 240 389 6.0E-4 T 28-03-2018 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 64 225 5.8E-30 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 Pfam PF10531 SLBB domain 251 289 3.1E-7 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS18620 09b54df95a28a4f2e86e27e93332eba3 476 SUPERFAMILY SSF140490 334 383 5.62E-12 T 28-03-2018 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Gene3D G3DSA:3.30.365.10 271 426 3.3E-30 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 SUPERFAMILY SSF54665 14 138 1.09E-31 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Gene3D G3DSA:3.30.365.10 445 567 3.0E-24 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 SUPERFAMILY SSF56003 163 730 1.96E-156 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Gene3D G3DSA:3.90.1170.50 18 139 9.9E-28 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 SMART SM01008 34 140 1.8E-27 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Gene3D G3DSA:3.30.365.10 166 270 5.7E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 166 670 6.2E-119 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Gene3D G3DSA:3.30.365.10 568 733 1.4E-45 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SmaCSM2_RS11175 954c87a91156d2777366454f76b0ae32 734 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 38 138 1.1E-18 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 Gene3D G3DSA:2.40.50.140 1 67 2.0E-28 T 28-03-2018 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.0E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 PRINTS PR00050 Cold shock protein signature 25 34 1.7E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 PRINTS PR00050 Cold shock protein signature 40 58 1.7E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 PIRSF PIRSF002599 1 68 4.4E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 SUPERFAMILY SSF50249 1 66 4.29E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15890 a44ee5d733ac87e50a418aba3d271621 68 SMART SM00357 3 67 6.7E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 Pfam PF12697 Alpha/beta hydrolase family 36 225 2.2E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 Gene3D G3DSA:3.40.50.1820 2 233 1.0E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 SUPERFAMILY SSF53474 4 230 1.11E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 75 88 2.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 74 2.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS21015 7c334216868e1980db79d72a94864b35 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 176 190 2.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 Gene3D G3DSA:2.60.40.1180 457 543 7.6E-10 T 28-03-2018 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 SUPERFAMILY SSF51011 475 540 4.14E-5 T 28-03-2018 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 Gene3D G3DSA:3.20.20.80 27 456 5.5E-64 T 28-03-2018 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 SMART SM00642 40 453 3.7E-30 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 Pfam PF00128 Alpha amylase, catalytic domain 84 417 6.8E-42 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SmaCSM2_RS05430 b9511ca42bd2434d64da68f12039818b 571 SUPERFAMILY SSF51445 30 462 1.87E-68 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS17440 acc85820e8df1815c76c59ea6ef95671 129 Gene3D G3DSA:3.10.180.10 1 129 2.8E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS17440 acc85820e8df1815c76c59ea6ef95671 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 1.0E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS17440 acc85820e8df1815c76c59ea6ef95671 129 SUPERFAMILY SSF54593 1 127 2.28E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Pfam PF00271 Helicase conserved C-terminal domain 489 598 1.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 SUPERFAMILY SSF52540 202 464 2.16E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Pfam PF00270 DEAD/DEAH box helicase 284 418 3.5E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Pfam PF17191 RecG wedge domain 22 180 1.2E-13 T 28-03-2018 IPR033454 RecG, wedge domain SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 37 673 8.3E-219 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Gene3D G3DSA:2.40.50.140 61 152 9.5E-10 T 28-03-2018 SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 SUPERFAMILY SSF52540 463 664 1.39E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 SMART SM00490 515 599 4.9E-21 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 SMART SM00487 276 470 2.0E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 SUPERFAMILY SSF50249 16 183 4.28E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Gene3D G3DSA:3.40.50.300 468 640 2.7E-29 T 28-03-2018 SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Gene3D G3DSA:3.40.50.300 265 467 2.2E-35 T 28-03-2018 SmaCSM2_RS17360 b997f5c63ed1ef4d1b287b74a617b364 703 Gene3D G3DSA:1.10.150.20 17 60 0.0015 T 28-03-2018 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 Gene3D G3DSA:3.40.50.300 182 382 3.1E-30 T 28-03-2018 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 SUPERFAMILY SSF52540 193 371 3.31E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 724 23.69 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 TIGRFAM TIGR00595 priA: primosomal protein N' 218 721 6.2E-173 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 Gene3D G3DSA:3.40.50.300 397 626 2.2E-20 T 28-03-2018 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 Pfam PF00270 DEAD/DEAH box helicase 199 361 1.9E-14 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 SMART SM00487 193 389 3.4E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 SMART SM00490 489 585 4.2E-10 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 Pfam PF00271 Helicase conserved C-terminal domain 502 584 6.7E-7 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 SUPERFAMILY SSF52540 518 610 3.67E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19135 6caa5773d36eda14cb794152d4062377 725 SUPERFAMILY SSF52540 384 490 3.67E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 SUPERFAMILY SSF48179 159 258 9.41E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 SUPERFAMILY SSF55021 299 362 1.34E-7 T 28-03-2018 SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 Gene3D G3DSA:3.40.50.720 1 165 4.5E-18 T 28-03-2018 SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 Gene3D G3DSA:3.30.70.260 294 374 7.8E-7 T 28-03-2018 SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 Pfam PF02153 Prephenate dehydrogenase 52 256 4.3E-23 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 Pfam PF01842 ACT domain 303 360 8.4E-9 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 SUPERFAMILY SSF51735 9 154 1.66E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS08775 e97745f8237903e314f1dc23a983a90e 374 Gene3D G3DSA:1.10.3660.10 167 290 1.6E-19 T 28-03-2018 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 97 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 Pfam PF06445 GyrI-like small molecule binding domain 127 270 3.7E-17 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 SUPERFAMILY SSF46689 54 104 4.48E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 SUPERFAMILY SSF46689 6 52 4.66E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 SMART SM00871 125 271 2.6E-17 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 Gene3D G3DSA:3.20.80.10 125 275 2.8E-27 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 Pfam PF12833 Helix-turn-helix domain 24 102 4.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 Gene3D G3DSA:1.10.10.60 4 56 1.2E-13 T 28-03-2018 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 SMART SM00342 18 101 1.3E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 Gene3D G3DSA:1.10.10.60 57 116 1.6E-10 T 28-03-2018 SmaCSM2_RS20470 e71c2b01fcf5a60a6d89a4419db3afea 275 SUPERFAMILY SSF55136 130 272 3.66E-24 T 28-03-2018 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 Pfam PF00437 Type II/IV secretion system protein 229 490 1.1E-76 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 418 432 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 SUPERFAMILY SSF160246 76 174 5.49E-14 T 28-03-2018 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 Gene3D G3DSA:3.40.50.300 325 606 5.5E-58 T 28-03-2018 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 SUPERFAMILY SSF52540 211 598 3.09E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 78 176 5.6E-17 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 Gene3D G3DSA:3.30.450.90 189 323 1.5E-44 T 28-03-2018 SmaCSM2_RS21440 9ce892eddf07a43a4ea896f4cd3b1b5d 611 SMART SM00382 351 472 1.5E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS17845 741357589a19460f7cf4e8f00260ac78 371 Pfam PF13439 Glycosyltransferase Family 4 16 168 4.6E-24 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SmaCSM2_RS17845 741357589a19460f7cf4e8f00260ac78 371 Gene3D G3DSA:3.40.50.2000 180 360 3.2E-24 T 28-03-2018 SmaCSM2_RS17845 741357589a19460f7cf4e8f00260ac78 371 Gene3D G3DSA:3.40.50.2000 2 179 3.9E-18 T 28-03-2018 SmaCSM2_RS17845 741357589a19460f7cf4e8f00260ac78 371 SUPERFAMILY SSF53756 1 368 3.36E-52 T 28-03-2018 SmaCSM2_RS17845 741357589a19460f7cf4e8f00260ac78 371 Pfam PF00534 Glycosyl transferases group 1 197 344 2.5E-15 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 SUPERFAMILY SSF55920 1 254 1.1E-82 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 Pfam PF00557 Metallopeptidase family M24 12 240 6.1E-50 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 107 3.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 3.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 3.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 68 81 3.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 Hamap MF_01974 Methionine aminopeptidase [map]. 2 250 36.573 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 Gene3D G3DSA:3.90.230.10 1 260 6.5E-76 T 28-03-2018 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 249 1.4E-84 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06200 86c5058491ec62a695b34335e952af2d 262 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 7.9E-53 T 28-03-2018 SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 SUPERFAMILY SSF51735 1 249 1.98E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 Gene3D G3DSA:3.40.50.720 51 252 5.7E-52 T 28-03-2018 SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS16405 3c2850dece9e46863d345d0132d117ee 252 Gene3D G3DSA:3.40.50.10090 1 50 5.5E-12 T 28-03-2018 SmaCSM2_RS04240 94f1645e72c460622ec86eb5cbb8678e 231 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 25 212 8.8E-31 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 SmaCSM2_RS04240 94f1645e72c460622ec86eb5cbb8678e 231 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 227 2.5E-51 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 SmaCSM2_RS15595 6c8d43c2985e6902c3fb9d80a29c0f25 473 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 472 1.1E-165 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 SmaCSM2_RS15595 6c8d43c2985e6902c3fb9d80a29c0f25 473 PIRSF PIRSF006060 1 441 1.0E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS15595 6c8d43c2985e6902c3fb9d80a29c0f25 473 PIRSF PIRSF006060 444 472 110.0 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS15595 6c8d43c2985e6902c3fb9d80a29c0f25 473 Pfam PF13520 Amino acid permease 8 413 1.9E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 Gene3D G3DSA:3.40.630.10 14 97 0.033 T 28-03-2018 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 Pfam PF04389 Peptidase family M28 298 501 1.3E-47 T 28-03-2018 IPR007484 Peptidase M28 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 SUPERFAMILY SSF53187 22 70 3.73E-63 T 28-03-2018 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 SUPERFAMILY SSF53187 282 525 3.73E-63 T 28-03-2018 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 Pfam PF02225 PA domain 130 218 7.5E-7 T 28-03-2018 IPR003137 PA domain SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 Gene3D G3DSA:3.50.30.30 104 255 1.4E-12 T 28-03-2018 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 SUPERFAMILY SSF52025 122 212 9.42E-8 T 28-03-2018 SmaCSM2_RS02300 a91debf5fedb94b5a21220a31a706a40 549 Gene3D G3DSA:3.40.630.10 256 528 1.7E-32 T 28-03-2018 SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 Gene3D G3DSA:2.160.20.20 38 189 6.3E-7 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 Gene3D G3DSA:2.160.20.20 190 721 7.9E-68 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 Pfam PF03212 Pertactin 597 714 4.8E-10 T 28-03-2018 IPR004899 Pertactin, central region SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 609 1082 1.5E-92 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 Pfam PF03797 Autotransporter beta-domain 812 1059 8.4E-36 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 Gene3D G3DSA:2.40.128.130 769 1082 9.9E-40 T 28-03-2018 SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 SUPERFAMILY SSF51126 280 721 9.42E-41 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 SMART SM00869 808 1071 2.5E-24 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS03855 1fef2567ea83c8d95988e76d3cb0944c 1082 SUPERFAMILY SSF103515 778 1082 4.97E-38 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS02075 08e2ce09e36a0c25ebe2e140e8e764ab 122 Pfam PF13391 HNH endonuclease 13 64 2.1E-7 T 28-03-2018 IPR003615 HNH nuclease SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:2.60.120.260 2259 2410 1.9E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:1.20.5.1230 978 1206 0.053 T 28-03-2018 SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:3.90.20.10 2411 2503 1.8E-4 T 28-03-2018 SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:3.90.20.10 1309 1420 0.0014 T 28-03-2018 SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:2.60.120.260 2032 2220 6.9E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:2.60.120.260 1829 2004 1.2E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:2.60.120.260 1421 1586 6.0E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS15365 c7a01b8cf4a33edb6bcb94634235c97e 2762 Gene3D G3DSA:2.60.120.260 2504 2681 1.3E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 115 5.0E-10 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 105 125 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 152 173 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 4.0E-36 T 28-03-2018 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 789 908 2.2E-30 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 Pfam PF13244 Domain of unknown function (DUF4040) 613 676 9.6E-18 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 SmaCSM2_RS19745 dd74f510a7c8a0e646fa6905835f40c5 943 Pfam PF00361 Proton-conducting membrane transporter 128 404 4.7E-63 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS00350 8097a365affe142550f7304012b48fba 307 PIRSF PIRSF019271 3 306 1.9E-95 T 28-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 SmaCSM2_RS00350 8097a365affe142550f7304012b48fba 307 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 42 277 3.0E-42 T 28-03-2018 IPR005519 Acid phosphatase, class B-like SmaCSM2_RS00350 8097a365affe142550f7304012b48fba 307 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 10 303 6.2E-67 T 28-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 SmaCSM2_RS00350 8097a365affe142550f7304012b48fba 307 Gene3D G3DSA:3.40.50.1000 58 247 1.5E-20 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS00350 8097a365affe142550f7304012b48fba 307 SUPERFAMILY SSF56784 75 285 2.85E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 50 174 9.8E-22 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Gene3D G3DSA:2.60.40.10 561 615 0.0029 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 177 520 4.9E-116 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 SUPERFAMILY SSF55545 48 176 5.76E-21 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Gene3D G3DSA:3.20.20.80 175 560 3.8E-130 T 28-03-2018 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Gene3D G3DSA:3.30.379.10 43 174 2.0E-21 T 28-03-2018 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 566 616 1.9E-5 T 28-03-2018 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 SUPERFAMILY SSF51445 177 533 5.12E-120 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 200 221 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 271 288 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 171 188 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 137 157 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 502 519 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 318 336 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS18245 ba6c978c391b6a1d1345397d87f082d3 785 PRINTS PR00738 Glycosyl hydrolase family 20 signature 340 353 3.8E-43 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 SUPERFAMILY SSF46689 16 74 8.72E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 Gene3D G3DSA:1.10.10.60 13 53 3.3E-11 T 28-03-2018 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 Gene3D G3DSA:1.10.10.60 54 140 8.6E-8 T 28-03-2018 SmaCSM2_RS11240 180909753a6b2804847ee46fb3a1fea8 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 9.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 SUPERFAMILY SSF52172 1 171 1.12E-33 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 Gene3D G3DSA:1.10.10.10 119 223 2.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 SMART SM00448 1 112 1.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 Gene3D G3DSA:3.40.50.2300 1 118 2.7E-29 T 28-03-2018 SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 5.3E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS07290 a21f6a2c5eb7d75548b9f1d007ac5517 223 SMART SM00862 145 220 6.6E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 207 239 1.8 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 76 107 6.5E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 259 290 140.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 297 328 0.087 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 163 194 3.6 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 122 154 4.8E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SMART SM00564 338 369 16.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 Gene3D G3DSA:2.140.10.10 27 199 1.5E-31 T 28-03-2018 SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 Gene3D G3DSA:2.140.10.10 277 402 5.9E-18 T 28-03-2018 SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 5 400 37.473 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 Pfam PF13360 PQQ-like domain 57 112 1.1E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 Pfam PF13360 PQQ-like domain 118 327 7.4E-46 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 9 399 9.4E-126 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB SmaCSM2_RS09065 6f350c919d3a8f143941cb3d1c4697e8 402 SUPERFAMILY SSF50998 42 397 5.2E-80 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 Gene3D G3DSA:3.40.47.10 14 233 9.9E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 Gene3D G3DSA:3.40.47.10 243 394 1.6E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 238 337 3.5E-22 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 94 232 6.3E-22 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 SMART SM00825 Beta-ketoacyl synthase 11 394 3.7E-7 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 SUPERFAMILY SSF53901 207 393 3.91E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 SUPERFAMILY SSF53901 4 232 3.02E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21075 6ca85c054a6acd85bd93e0389adb8484 394 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 150 166 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SmaCSM2_RS12725 cc5d7e9fda65ee21584b24d7bac49947 344 Gene3D G3DSA:3.90.1210.10 42 120 2.4E-7 T 28-03-2018 SmaCSM2_RS12725 cc5d7e9fda65ee21584b24d7bac49947 344 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 12 338 4.3E-46 T 28-03-2018 IPR017592 Pilus assembly, Flp-type CpaB SmaCSM2_RS12725 cc5d7e9fda65ee21584b24d7bac49947 344 SMART SM00858 47 107 2.5E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SmaCSM2_RS12725 cc5d7e9fda65ee21584b24d7bac49947 344 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 109 249 4.8E-27 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SmaCSM2_RS12725 cc5d7e9fda65ee21584b24d7bac49947 344 Pfam PF08666 SAF domain 48 106 1.8E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 SUPERFAMILY SSF52540 149 393 7.11E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 SMART SM00448 9 124 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Pfam PF02954 Bacterial regulatory protein, Fis family 436 473 5.4E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 SUPERFAMILY SSF46689 405 473 8.96E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Pfam PF00158 Sigma-54 interaction domain 149 315 1.1E-66 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 11 474 3.4E-205 T 28-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Gene3D G3DSA:3.40.50.2300 5 145 3.2E-30 T 28-03-2018 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Gene3D G3DSA:1.10.10.60 394 475 7.6E-11 T 28-03-2018 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 235 250 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 459 479 6.0E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 442 459 6.0E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 362 371 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Pfam PF00072 Response regulator receiver domain 11 118 8.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 SMART SM00382 169 312 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Gene3D G3DSA:1.10.8.60 322 393 2.3E-23 T 28-03-2018 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 SUPERFAMILY SSF52172 10 193 7.4E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS00665 da3a0608035607bf2cff6b22d93588bf 482 Gene3D G3DSA:3.40.50.300 146 321 1.5E-28 T 28-03-2018 SmaCSM2_RS01650 9946ccdc5e9853fae2e09ea0d99d697e 569 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 566 27.779 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SmaCSM2_RS01650 9946ccdc5e9853fae2e09ea0d99d697e 569 Pfam PF03814 Potassium-transporting ATPase A subunit 6 564 1.3E-209 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SmaCSM2_RS01650 9946ccdc5e9853fae2e09ea0d99d697e 569 PIRSF PIRSF001294 1 568 1.4E-215 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SmaCSM2_RS01650 9946ccdc5e9853fae2e09ea0d99d697e 569 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 566 9.6E-160 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SmaCSM2_RS10280 acff76dbd52475136e129e8fbd8ae75a 249 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 244 2.1E-20 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain SmaCSM2_RS10280 acff76dbd52475136e129e8fbd8ae75a 249 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 123 2.2E-28 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G SmaCSM2_RS10280 acff76dbd52475136e129e8fbd8ae75a 249 SUPERFAMILY SSF117143 77 206 1.24E-13 T 28-03-2018 SmaCSM2_RS10280 acff76dbd52475136e129e8fbd8ae75a 249 Pfam PF00460 Flagella basal body rod protein 5 35 1.8E-7 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 Pfam PF13662 Toprim domain 79 170 7.1E-24 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 Gene3D G3DSA:3.40.1360.10 76 169 2.3E-33 T 28-03-2018 SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 SUPERFAMILY SSF111304 4 197 1.7E-69 T 28-03-2018 IPR023627 Recombination protein RecR SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 94.873 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 Pfam PF02132 RecR protein 39 76 2.3E-11 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 SMART SM00493 79 164 1.8E-13 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS04735 e440d6e30da01a5bc5e36370e64dd6b5 199 TIGRFAM TIGR00615 recR: recombination protein RecR 4 194 2.4E-71 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 Gene3D G3DSA:2.40.160.50 166 558 8.5E-53 T 28-03-2018 SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 PIRSF PIRSF029745 2 558 1.1E-150 T 28-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 Pfam PF08479 POTRA domain, ShlB-type 60 138 3.1E-21 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 202 522 7.1E-113 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 Pfam PF17287 POTRA domain 144 193 4.8E-17 T 28-03-2018 IPR035251 ShlB, POTRA domain SmaCSM2_RS06135 69a9f8de5dbce5b5a7b71006966435b3 558 Gene3D G3DSA:3.10.20.310 79 138 3.6E-10 T 28-03-2018 SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 Gene3D G3DSA:1.10.287.470 97 154 2.2E-6 T 28-03-2018 SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 Gene3D G3DSA:2.40.50.100 156 330 2.3E-4 T 28-03-2018 SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 SUPERFAMILY SSF111369 52 267 7.72E-39 T 28-03-2018 SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 343 3.2E-73 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 262 3.5E-31 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 69 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS17105 92148dbd3f443a4915f10774e41a664b 368 Gene3D G3DSA:2.40.50.100 21 95 0.0014 T 28-03-2018 SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 SUPERFAMILY SSF46785 4 112 1.09E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 Gene3D G3DSA:3.40.190.10 92 177 1.9E-13 T 28-03-2018 SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 Pfam PF03466 LysR substrate binding domain 88 296 5.9E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 Gene3D G3DSA:1.10.10.10 3 84 3.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 SUPERFAMILY SSF53850 89 296 4.34E-41 T 28-03-2018 SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS21285 9e5fb43c086f6bb3b1d914a2bcf81dfb 297 Gene3D G3DSA:3.40.190.10 178 267 1.1E-21 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SUPERFAMILY SSF58104 554 835 6.67E-64 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Gene3D G3DSA:1.20.120.570 63 191 0.28 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SUPERFAMILY SSF55785 378 477 2.27E-9 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Pfam PF13188 PAS domain 392 439 5.7E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Gene3D G3DSA:1.10.287.950 496 642 3.1E-19 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Gene3D G3DSA:1.10.287.950 643 838 8.2E-45 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SUPERFAMILY SSF158472 328 379 1.11E-7 T 28-03-2018 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SMART SM00283 587 834 6.0E-77 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 762 791 4.6E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 390 4.6E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 608 637 4.6E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 685 712 4.6E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 714 743 4.6E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 648 800 2.2E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SMART SM00091 391 458 2.1E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SMART SM00304 534 579 7.2 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 SMART SM00304 328 381 6.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS19255 fca54f12512a89e46f83af1881208bac 845 Gene3D G3DSA:3.30.450.20 387 485 9.9E-9 T 28-03-2018 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 SUPERFAMILY SSF48179 175 319 2.55E-67 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 320 41.767 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 8 318 1.2E-125 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 8 168 4.1E-68 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 175 318 4.7E-63 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 Gene3D G3DSA:3.40.50.720 1 37 0.0042 T 28-03-2018 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 SUPERFAMILY SSF51735 4 174 7.24E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 PIRSF PIRSF000116 2 201 1.2E-39 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 PIRSF PIRSF000116 194 322 1.4E-13 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SmaCSM2_RS17740 217d76d8137eff75525b15e9a603c73e 324 Gene3D G3DSA:1.10.1040.10 54 322 8.3E-109 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 Gene3D G3DSA:1.10.10.10 1 88 7.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 Pfam PF03466 LysR substrate binding domain 96 283 3.1E-22 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.7E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 SUPERFAMILY SSF46785 6 114 1.99E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 Gene3D G3DSA:3.40.190.10 176 252 1.3E-9 T 28-03-2018 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 Gene3D G3DSA:3.40.190.10 95 175 4.2E-11 T 28-03-2018 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13765 42bb191cae7116305172d086efbf35b6 294 SUPERFAMILY SSF53850 95 285 7.78E-25 T 28-03-2018 SmaCSM2_RS03090 a077b127852b436e8584be75170ae0a3 157 Gene3D G3DSA:3.10.450.160 48 155 2.8E-17 T 28-03-2018 SmaCSM2_RS03090 a077b127852b436e8584be75170ae0a3 157 Pfam PF11776 Nickel/cobalt transporter regulator 100 151 5.9E-20 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS03090 a077b127852b436e8584be75170ae0a3 157 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 97 153 2.0E-14 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 SMART SM00418 10 88 7.6E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 4.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 4.2E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 Gene3D G3DSA:1.10.10.10 2 114 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 Pfam PF12840 Helix-turn-helix domain 9 68 3.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08540 ea9d356514b521a7333ef869236e8dff 119 SUPERFAMILY SSF46785 8 107 3.49E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19380 4657e8b575b3bcf14f31b2ded80e8229 442 SMART SM00195 309 440 3.0E-5 T 28-03-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 SmaCSM2_RS19380 4657e8b575b3bcf14f31b2ded80e8229 442 Gene3D G3DSA:3.90.190.10 296 435 4.9E-13 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS19380 4657e8b575b3bcf14f31b2ded80e8229 442 SUPERFAMILY SSF52799 297 432 1.56E-16 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS19380 4657e8b575b3bcf14f31b2ded80e8229 442 Pfam PF00782 Dual specificity phosphatase, catalytic domain 349 434 2.9E-9 T 28-03-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 SmaCSM2_RS07110 f368b1da6179c017b48c3a5f680e3574 370 Pfam PF12698 ABC-2 family transporter protein 22 363 3.9E-47 T 28-03-2018 SmaCSM2_RS07110 f368b1da6179c017b48c3a5f680e3574 370 Gene3D G3DSA:3.40.1710.10 39 190 1.0E-16 T 28-03-2018 SmaCSM2_RS07110 f368b1da6179c017b48c3a5f680e3574 370 PRINTS PR00164 ABC-2 type transport system membrane protein signature 292 311 2.5E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS07110 f368b1da6179c017b48c3a5f680e3574 370 PRINTS PR00164 ABC-2 type transport system membrane protein signature 312 331 2.5E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS07110 f368b1da6179c017b48c3a5f680e3574 370 PRINTS PR00164 ABC-2 type transport system membrane protein signature 255 279 2.5E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 Pfam PF12840 Helix-turn-helix domain 2 61 5.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 Gene3D G3DSA:1.10.10.10 1 76 3.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 SUPERFAMILY SSF46785 1 97 2.43E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS05565 0a5701caddb75b7f85202c3257bcbfe9 103 SMART SM00418 3 82 1.3E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 SMART SM00388 238 303 3.7E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 455 2.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Pfam PF08521 Two-component sensor kinase N-terminal 20 162 9.3E-27 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Gene3D G3DSA:3.30.565.10 307 459 2.9E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 SMART SM00387 347 457 8.6E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 301 1.2E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 SUPERFAMILY SSF55874 293 455 8.38E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Gene3D G3DSA:1.20.5.1040 6 65 7.8E-4 T 28-03-2018 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 SUPERFAMILY SSF47384 221 301 6.47E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06255 74e4fa0af357a085ac5dc98659de2457 459 Gene3D G3DSA:1.10.287.130 213 299 3.1E-9 T 28-03-2018 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 2 658 35.998 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Gene3D G3DSA:3.40.50.300 384 608 2.6E-37 T 28-03-2018 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Gene3D G3DSA:3.40.50.300 1 133 4.9E-24 T 28-03-2018 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Gene3D G3DSA:3.40.50.300 134 273 4.4E-30 T 28-03-2018 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 262 1.6E-71 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Gene3D G3DSA:3.40.50.300 274 377 6.0E-25 T 28-03-2018 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 Pfam PF13361 UvrD-like helicase C-terminal domain 269 603 1.7E-63 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SmaCSM2_RS00335 f2b4d9a25d3c0fb4981455b031abbbb6 658 SUPERFAMILY SSF52540 2 628 3.74E-159 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 179 7.0E-17 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Pfam PF00679 Elongation factor G C-terminus 404 482 1.7E-18 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Hamap MF_00071 Elongation factor 4 [lepA]. 1 602 296.726 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 6.2E-52 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Gene3D G3DSA:3.30.70.240 396 554 4.5E-25 T 28-03-2018 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Pfam PF03144 Elongation factor Tu domain 2 210 280 9.7E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Gene3D G3DSA:2.40.30.10 193 292 3.6E-23 T 28-03-2018 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 SUPERFAMILY SSF52540 5 234 3.4E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Pfam PF00009 Elongation factor Tu GTP binding domain 8 186 1.5E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 SMART SM00838 403 491 0.0045 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 TIGRFAM TIGR01393 lepA: elongation factor 4 8 600 1.4E-294 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 SUPERFAMILY SSF54980 404 498 3.17E-23 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 PRINTS PR00315 GTP-binding elongation factor signature 79 89 2.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 PRINTS PR00315 GTP-binding elongation factor signature 54 62 2.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 PRINTS PR00315 GTP-binding elongation factor signature 95 106 2.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Gene3D G3DSA:3.30.70.870 293 372 5.7E-29 T 28-03-2018 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 Gene3D G3DSA:3.40.50.300 4 190 3.2E-36 T 28-03-2018 SmaCSM2_RS15955 0435f1678a700b06e05535be571a9d9f 602 SUPERFAMILY SSF54980 297 375 6.47E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 SUPERFAMILY SSF88659 92 163 7.63E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 162 2.7E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 Gene3D G3DSA:1.10.1740.10 3 76 2.3E-14 T 28-03-2018 SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 Pfam PF04542 Sigma-70 region 2 14 79 1.1E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 Gene3D G3DSA:1.10.10.10 77 167 4.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 Pfam PF08281 Sigma-70, region 4 111 163 2.8E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12630 ab9e3efca24dcf36b96572528a09a5f6 172 SUPERFAMILY SSF88946 7 76 6.28E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 100 106 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 8 630 29.037 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 SUPERFAMILY SSF55874 8 208 4.06E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 SUPERFAMILY SSF54211 212 334 1.74E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Pfam PF08676 MutL C terminal dimerisation domain 443 590 3.1E-49 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 9 314 9.3E-98 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 217 333 3.0E-39 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 SMART SM01340 216 334 6.5E-58 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Gene3D G3DSA:3.30.230.10 221 333 1.1E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 31 121 1.1E-8 T 28-03-2018 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 SUPERFAMILY SSF118116 443 632 2.35E-59 T 28-03-2018 SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 Gene3D G3DSA:3.30.565.10 1 206 1.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS14755 d2a2e0e2c9a9b19936a553506a5eca62 634 SMART SM00853 447 590 8.2E-56 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SmaCSM2_RS16855 d44d0093b43241b826a25401ae6b4788 593 Pfam PF00723 Glycosyl hydrolases family 15 221 582 1.5E-28 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SmaCSM2_RS16855 d44d0093b43241b826a25401ae6b4788 593 Gene3D G3DSA:1.50.10.10 188 543 7.4E-83 T 28-03-2018 SmaCSM2_RS16855 d44d0093b43241b826a25401ae6b4788 593 SUPERFAMILY SSF48208 205 590 1.32E-93 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 Gene3D G3DSA:3.40.50.200 44 376 6.0E-56 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 85 95 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 Pfam PF00082 Subtilase family 80 364 8.6E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 SMART SM00869 682 938 1.4E-18 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 Gene3D G3DSA:2.40.128.130 638 944 1.5E-23 T 28-03-2018 SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 SUPERFAMILY SSF52743 62 376 1.31E-56 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 405 435 2.2E-12 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 PRINTS PR00723 Subtilisin serine protease family (S8) signature 313 329 1.5E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 PRINTS PR00723 Subtilisin serine protease family (S8) signature 80 99 1.5E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 PRINTS PR00723 Subtilisin serine protease family (S8) signature 121 134 1.5E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 Pfam PF03797 Autotransporter beta-domain 686 927 3.1E-27 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 SUPERFAMILY SSF103515 647 933 4.71E-31 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 314 324 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 125 135 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SmaCSM2_RS15835 1b88415ab8444a4451dfb7891f8df247 947 Pfam PF12951 Passenger-associated-transport-repeat 406 435 2.5E-10 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 Gene3D G3DSA:3.90.1720.10 256 418 5.2E-4 T 28-03-2018 SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 Gene3D G3DSA:1.10.101.10 455 537 1.6E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 SUPERFAMILY SSF53955 10 135 5.77E-11 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 Pfam PF01471 Putative peptidoglycan binding domain 471 531 9.1E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 Gene3D G3DSA:1.10.530.10 1 255 1.0E-15 T 28-03-2018 SmaCSM2_RS00810 35a56376087cd8714b30a6efc0152493 664 SUPERFAMILY SSF47090 462 531 2.62E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 Gene3D G3DSA:1.10.10.10 1 87 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 Pfam PF03466 LysR substrate binding domain 97 291 7.1E-20 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 294 7.2E-119 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 Gene3D G3DSA:3.40.190.10 95 196 3.5E-42 T 28-03-2018 SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 SUPERFAMILY SSF46785 6 113 1.79E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS06190 e16f6eff2e0dad6bf55174daf60a570b 297 SUPERFAMILY SSF53850 93 292 8.32E-26 T 28-03-2018 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 SUPERFAMILY SSF100920 347 511 2.88E-32 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 Pfam PF00012 Hsp70 protein 78 560 5.0E-110 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 Pfam PF00012 Hsp70 protein 2 73 2.2E-15 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 Gene3D G3DSA:2.60.34.10 331 547 7.5E-38 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 5 12 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 SUPERFAMILY SSF53067 1 155 3.24E-48 T 28-03-2018 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 SUPERFAMILY SSF53067 160 340 6.79E-41 T 28-03-2018 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 Gene3D G3DSA:3.30.420.40 1 170 2.8E-55 T 28-03-2018 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 111 131 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 171 181 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 350 369 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 1 14 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 325 345 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 440 456 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 29 41 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 PRINTS PR00301 70kDa heat shock protein signature 294 310 2.5E-41 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 165 178 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SmaCSM2_RS21410 3c6f8112e5efea95b027c8c59b5dbaa2 562 Gene3D G3DSA:3.30.420.40 171 322 2.6E-32 T 28-03-2018 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 Gene3D G3DSA:3.40.640.10 133 380 2.9E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 5.3E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 Gene3D G3DSA:3.90.1150.10 381 478 4.8E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 Gene3D G3DSA:1.10.10.10 2 78 6.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 SMART SM00345 17 76 8.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 Pfam PF00155 Aminotransferase class I and II 143 461 7.7E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 SUPERFAMILY SSF46785 12 79 1.53E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02540 fa1219435efe825812b42888b235de86 482 SUPERFAMILY SSF53383 97 477 2.04E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 Pfam PF00484 Carbonic anhydrase 37 189 1.4E-51 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 SMART SM00947 30 193 6.3E-71 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 Gene3D G3DSA:3.40.1050.10 1 219 5.5E-74 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS13935 9fb98308bbd04ddcfc1878f9a66678b7 220 SUPERFAMILY SSF53056 2 209 1.7E-75 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 SUPERFAMILY SSF46785 5 105 7.46E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 2.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 SMART SM00418 11 90 4.4E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 Pfam PF12840 Helix-turn-helix domain 10 70 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09195 09cec0990c33f2e5ed738c228f7b7523 110 Gene3D G3DSA:1.10.10.10 1 99 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06330 6f1802d32f6efa113d404685bffbea76 285 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 271 37.852 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 SmaCSM2_RS06330 6f1802d32f6efa113d404685bffbea76 285 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 32 281 4.0E-92 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 SmaCSM2_RS06330 6f1802d32f6efa113d404685bffbea76 285 Gene3D G3DSA:3.40.50.150 1 285 2.6E-76 T 28-03-2018 SmaCSM2_RS06330 6f1802d32f6efa113d404685bffbea76 285 SUPERFAMILY SSF53335 8 280 5.57E-80 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 Gene3D G3DSA:4.10.960.10 62 172 9.8E-32 T 28-03-2018 SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 108 131 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 SUPERFAMILY SSF50447 5 215 7.24E-79 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 Pfam PF00297 Ribosomal protein L3 103 188 4.5E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 211 3.7E-86 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03990 6ce5e8e696a2ba5646003012a6b5b4b7 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 214 39.454 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13015 687bfe2f1bb274e27754ede4681ce516 257 PIRSF PIRSF004848 10 248 4.8E-70 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SmaCSM2_RS13015 687bfe2f1bb274e27754ede4681ce516 257 Pfam PF01168 Alanine racemase, N-terminal domain 24 242 3.4E-23 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SmaCSM2_RS13015 687bfe2f1bb274e27754ede4681ce516 257 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 17 242 3.9E-54 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SmaCSM2_RS13015 687bfe2f1bb274e27754ede4681ce516 257 SUPERFAMILY SSF51419 12 240 1.06E-73 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS13015 687bfe2f1bb274e27754ede4681ce516 257 Gene3D G3DSA:3.20.20.10 8 248 8.3E-65 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 SMART SM00829 14 338 3.8E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 Gene3D G3DSA:3.90.180.10 2 150 1.5E-53 T 28-03-2018 SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 SUPERFAMILY SSF51735 143 308 4.15E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 Gene3D G3DSA:3.40.50.720 151 333 1.3E-32 T 28-03-2018 SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 SUPERFAMILY SSF50129 2 184 6.85E-56 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 Pfam PF00107 Zinc-binding dehydrogenase 179 304 3.8E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS00230 4eb989884178a4e9616f8ecf6a7be41d 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 135 2.5E-33 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS21770 6f0ff1febafefc1e4cdf5130c9f91390 46 ProSitePatterns PS00784 Ribosomal protein L34 signature. 4 23 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS21770 6f0ff1febafefc1e4cdf5130c9f91390 46 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 3 46 16.287 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21770 6f0ff1febafefc1e4cdf5130c9f91390 46 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 46 1.3E-25 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21770 6f0ff1febafefc1e4cdf5130c9f91390 46 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 4 44 7.0E-12 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21770 6f0ff1febafefc1e4cdf5130c9f91390 46 Pfam PF00468 Ribosomal protein L34 3 46 2.2E-25 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06010 c812e4b61b2fe463ba2ef235800ae267 212 Gene3D G3DSA:1.20.120.80 27 212 4.6E-52 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06010 c812e4b61b2fe463ba2ef235800ae267 212 Pfam PF00510 Cytochrome c oxidase subunit III 33 210 3.5E-14 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06010 c812e4b61b2fe463ba2ef235800ae267 212 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 33 212 4.5E-82 T 28-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 SmaCSM2_RS06010 c812e4b61b2fe463ba2ef235800ae267 212 SUPERFAMILY SSF81452 28 210 2.62E-57 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Gene3D G3DSA:3.30.565.10 17 217 2.7E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 SUPERFAMILY SSF55874 4 215 1.44E-68 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 SMART SM00387 27 173 1.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 SMART SM00433 34 623 1.7E-210 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 447 468 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 536 558 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 502 518 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 468 480 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 310 325 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 337 360 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 293 309 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR01098 Topoisomerase IV subunit B signature 361 386 1.6E-93 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Gene3D G3DSA:3.30.230.10 218 382 3.5E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 7.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Pfam PF00204 DNA gyrase B 218 383 9.3E-37 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 SUPERFAMILY SSF54211 217 380 6.64E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 ProSitePatterns PS00177 DNA topoisomerase II signature. 415 423 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 66 79 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 413 427 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 109 123 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 496 513 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 561 577 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 31 46 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 265 278 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 516 528 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 PRINTS PR00418 DNA topoisomerase II family signature 478 494 4.8E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 627 46.496 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Pfam PF01751 Toprim domain 412 519 8.9E-13 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Gene3D G3DSA:3.40.50.670 394 626 2.5E-75 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 557 619 4.6E-22 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 4 624 6.7E-292 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS08000 5c0eedb4205bf3bca7619b82edbe8d7d 629 SUPERFAMILY SSF56719 387 620 1.1E-74 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Gene3D G3DSA:2.120.10.90 499 743 7.3E-42 T 28-03-2018 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 13 742 0.0 T 28-03-2018 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 472 3.8E-132 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 SUPERFAMILY SSF101904 501 743 1.1E-48 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Gene3D G3DSA:1.10.268.10 348 487 1.5E-43 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 SUPERFAMILY SSF56719 35 487 1.31E-150 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 745 33.593 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 SMART SM00434 15 465 6.0E-222 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 649 698 4.9E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 602 643 0.16 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS06740 fc0985ca19eedacab75f59a9c85c9c0b 747 Gene3D G3DSA:3.90.199.10 38 287 2.6E-96 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS07435 027cd7b34bc4ee71feaca2bf144b837b 143 Pfam PF04343 Protein of unknown function, DUF488 14 131 8.9E-23 T 28-03-2018 IPR007438 Protein of unknown function DUF488 SmaCSM2_RS19370 f4e7e4df02eab1280d1f25f91d58ded2 209 SMART SM00563 34 156 4.4E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS19370 f4e7e4df02eab1280d1f25f91d58ded2 209 Pfam PF01553 Acyltransferase 31 153 4.8E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS19370 f4e7e4df02eab1280d1f25f91d58ded2 209 SUPERFAMILY SSF69593 17 199 2.88E-28 T 28-03-2018 SmaCSM2_RS19370 f4e7e4df02eab1280d1f25f91d58ded2 209 Gene3D G3DSA:3.40.1130.10 15 202 1.2E-27 T 28-03-2018 SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 Pfam PF01545 Cation efflux family 12 217 1.3E-32 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 SUPERFAMILY SSF160240 223 296 4.45E-5 T 28-03-2018 SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 SUPERFAMILY SSF161111 7 220 2.62E-40 T 28-03-2018 SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 Gene3D G3DSA:3.30.70.1350 219 308 4.8E-5 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 Gene3D G3DSA:1.20.1510.10 7 218 1.0E-35 T 28-03-2018 SmaCSM2_RS11660 642e166ff70c6c410d838018527d3157 319 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 301 1.7E-40 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 SUPERFAMILY SSF81442 42 558 3.01E-182 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 646 0.0 T 28-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 119 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 165 177 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 460 481 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 197 215 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 226 245 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 368 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 277 298 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 123 147 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 410 429 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 338 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 400 2.0E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 279 333 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 503 9.4E-138 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 Gene3D G3DSA:1.10.287.70 573 639 2.2E-15 T 28-03-2018 SmaCSM2_RS06005 219c2934feae03f04e9fe62bc211b7e7 665 Gene3D G3DSA:1.20.210.10 42 560 6.2E-189 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 Gene3D G3DSA:3.50.50.60 5 266 7.0E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 625 42.157 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 SUPERFAMILY SSF51905 8 69 4.33E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 SUPERFAMILY SSF51905 100 262 4.33E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 SMART SM01228 547 618 1.1E-41 T 28-03-2018 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 Pfam PF13932 GidA associated domain 403 617 1.1E-73 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 Pfam PF01134 Glucose inhibited division protein A 9 399 6.3E-165 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 SmaCSM2_RS20690 6ef691f88234ad6fd4de19763b39dc9c 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 622 7.7E-272 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 SmaCSM2_RS20570 00bf92add154d687413eb5a8203b8d97 451 SUPERFAMILY SSF55347 169 359 2.94E-7 T 28-03-2018 SmaCSM2_RS20570 00bf92add154d687413eb5a8203b8d97 451 Gene3D G3DSA:3.30.360.10 171 451 3.0E-74 T 28-03-2018 SmaCSM2_RS20570 00bf92add154d687413eb5a8203b8d97 451 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 32 133 3.8E-8 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SmaCSM2_RS20570 00bf92add154d687413eb5a8203b8d97 451 Gene3D G3DSA:3.40.50.720 14 170 8.4E-25 T 28-03-2018 SmaCSM2_RS20570 00bf92add154d687413eb5a8203b8d97 451 SUPERFAMILY SSF51735 23 191 3.51E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 SUPERFAMILY SSF55060 168 284 3.36E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 Gene3D G3DSA:3.30.70.890 169 287 3.1E-24 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 PIRSF PIRSF010376 9 287 1.9E-80 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 SUPERFAMILY SSF54211 12 166 5.16E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 Gene3D G3DSA:3.30.230.10 11 167 4.0E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 Pfam PF08544 GHMP kinases C terminal 213 268 1.9E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 13 285 6.2E-70 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 11 276 30.287 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SmaCSM2_RS03825 54ef27b3bdcd3690a7f556413f90e652 289 Pfam PF00288 GHMP kinases N terminal domain 94 151 3.7E-6 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SmaCSM2_RS17595 dea98325fbf02934f036e96b740f7fd8 192 SMART SM00464 6 191 6.4E-6 T 28-03-2018 IPR003111 Lon, substrate-binding domain SmaCSM2_RS17595 dea98325fbf02934f036e96b740f7fd8 192 SUPERFAMILY SSF88697 7 191 4.47E-43 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS17595 dea98325fbf02934f036e96b740f7fd8 192 Gene3D G3DSA:1.10.4060.10 116 192 7.1E-9 T 28-03-2018 SmaCSM2_RS17595 dea98325fbf02934f036e96b740f7fd8 192 Gene3D G3DSA:2.30.130.40 4 114 4.0E-21 T 28-03-2018 SmaCSM2_RS17595 dea98325fbf02934f036e96b740f7fd8 192 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 191 2.4E-15 T 28-03-2018 IPR003111 Lon, substrate-binding domain SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 PIRSF PIRSF019422 1 387 4.5E-119 T 28-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 Gene3D G3DSA:2.40.40.10 26 245 8.7E-36 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 Gene3D G3DSA:2.40.40.10 246 387 5.8E-35 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 Pfam PF03562 MltA specific insert domain 59 285 8.5E-79 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 Pfam PF06725 3D domain 308 379 8.4E-24 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 SMART SM00925 131 286 3.1E-85 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 SmaCSM2_RS00650 6314bdd1df7098beb2feb55d6c137e87 388 SUPERFAMILY SSF50685 37 385 2.13E-120 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 SMART SM00631 61 346 3.1E-5 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 Pfam PF00246 Zinc carboxypeptidase 68 238 3.8E-18 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 Gene3D G3DSA:3.40.50.880 618 858 1.1E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 Gene3D G3DSA:3.40.630.10 56 350 6.5E-39 T 28-03-2018 SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 SUPERFAMILY SSF52317 659 853 7.67E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 SUPERFAMILY SSF53187 130 344 3.97E-51 T 28-03-2018 SmaCSM2_RS02600 2830f84d91499d8a2e74e9a242493ec5 864 SUPERFAMILY SSF53187 53 103 3.97E-51 T 28-03-2018 SmaCSM2_RS15125 80c9f6f5866ed651c8122205ac4e6691 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 19.899 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SmaCSM2_RS15125 80c9f6f5866ed651c8122205ac4e6691 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 3.1E-24 T 28-03-2018 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 Gene3D G3DSA:3.20.20.70 132 316 8.9E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 Pfam PF02581 Thiamine monophosphate synthase 136 313 1.2E-34 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 SUPERFAMILY SSF51391 118 315 1.03E-43 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 Pfam PF00293 NUDIX domain 10 127 7.9E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 PRINTS PR00502 NUDIX hydrolase family signature 51 66 3.2E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 PRINTS PR00502 NUDIX hydrolase family signature 37 51 3.2E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 TIGRFAM TIGR00586 mutt: mutator mutT protein 6 132 1.6E-34 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 SUPERFAMILY SSF55811 5 131 1.9E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS03310 811403abed38afb525e0e9c992bdfe44 317 Gene3D G3DSA:3.90.79.10 3 131 1.5E-30 T 28-03-2018 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.7E-101 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.239 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 SUPERFAMILY SSF52313 6 230 3.27E-92 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 Gene3D G3DSA:3.40.50.10490 5 263 1.5E-93 T 28-03-2018 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 Pfam PF00318 Ribosomal protein S2 9 224 1.0E-92 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS06650 a8a1d4a1e09b4b0a30097ebcfc0dcc72 268 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.2E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 Gene3D G3DSA:2.40.170.20 173 907 2.5E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 SUPERFAMILY SSF56935 644 688 8.55E-89 T 28-03-2018 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 SUPERFAMILY SSF56935 307 603 8.55E-89 T 28-03-2018 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 SUPERFAMILY SSF56935 27 229 8.55E-89 T 28-03-2018 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 SUPERFAMILY SSF56935 740 907 8.55E-89 T 28-03-2018 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 Pfam PF00593 TonB dependent receptor 344 906 2.6E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 Gene3D G3DSA:2.170.130.10 28 172 3.4E-31 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12870 ec1fa1ee2fe200180d178a1b6de7f976 908 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 169 6.3E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF04539 Sigma-70 region 3 461 537 2.1E-30 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 575 601 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 3 615 45.78 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 378 614 1.5E-121 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 SUPERFAMILY SSF88946 120 449 2.35E-96 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Gene3D G3DSA:1.10.601.10 2 119 1.1E-14 T 28-03-2018 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Gene3D G3DSA:1.10.601.10 120 451 3.8E-98 T 28-03-2018 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF04542 Sigma-70 region 2 382 451 1.7E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 378 603 9.1E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 PRINTS PR00046 Major sigma-70 factor signature 406 419 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 PRINTS PR00046 Major sigma-70 factor signature 430 438 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 PRINTS PR00046 Major sigma-70 factor signature 554 566 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 PRINTS PR00046 Major sigma-70 factor signature 575 590 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 PRINTS PR00046 Major sigma-70 factor signature 590 601 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 SUPERFAMILY SSF88659 455 528 2.45E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF00140 Sigma-70 factor, region 1.2 103 134 5.3E-13 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Gene3D G3DSA:1.10.10.10 544 615 6.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 SUPERFAMILY SSF88659 512 614 1.83E-27 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF04546 Sigma-70, non-essential region 144 351 4.9E-51 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF04545 Sigma-70, region 4 550 603 1.8E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Gene3D G3DSA:1.10.10.10 452 502 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 406 419 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS18995 dea9cbedf7df131b9883f1064356c9a8 617 Pfam PF03979 Sigma-70 factor, region 1.1 8 86 3.8E-28 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 SmaCSM2_RS02490 2aac8a23f1184c5b406189036a4e6d0c 303 SUPERFAMILY SSF56281 12 259 3.22E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS02490 2aac8a23f1184c5b406189036a4e6d0c 303 Pfam PF00753 Metallo-beta-lactamase superfamily 52 237 3.6E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS02490 2aac8a23f1184c5b406189036a4e6d0c 303 Gene3D G3DSA:3.60.15.10 38 303 1.7E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS02490 2aac8a23f1184c5b406189036a4e6d0c 303 SMART SM00849 52 237 2.0E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 Gene3D G3DSA:3.20.20.70 2 378 1.6E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 SUPERFAMILY SSF51395 223 375 3.91E-100 T 28-03-2018 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 SUPERFAMILY SSF51395 7 193 3.91E-100 T 28-03-2018 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 PIRSF PIRSF000138 2 378 8.7E-123 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 379 74.567 T 28-03-2018 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 SmaCSM2_RS12905 3314160dad7e30a6fb325f2b87d99f82 379 Pfam PF01070 FMN-dependent dehydrogenase 13 375 1.2E-126 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 219 2.6E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Pfam PF00990 Diguanylate cyclase, GGDEF domain 477 634 9.6E-48 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SMART SM00267 466 638 7.8E-62 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SUPERFAMILY SSF55785 143 216 8.03E-14 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SUPERFAMILY SSF55785 370 474 1.36E-10 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SUPERFAMILY SSF141868 653 904 5.75E-86 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SMART SM00086 171 214 2.3E-9 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SMART SM00086 299 341 25.0 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SMART SM00086 425 466 0.19 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Gene3D G3DSA:3.20.20.450 647 907 1.5E-92 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Pfam PF08447 PAS fold 142 208 7.1E-18 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Pfam PF08448 PAS fold 250 343 4.7E-5 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Gene3D G3DSA:3.30.70.270 481 646 9.8E-58 T 28-03-2018 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SUPERFAMILY SSF55785 211 339 4.89E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Gene3D G3DSA:3.30.450.20 6 235 4.0E-22 T 28-03-2018 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Gene3D G3DSA:3.30.450.20 350 480 2.4E-12 T 28-03-2018 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SUPERFAMILY SSF55073 482 640 1.46E-48 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 SMART SM00052 648 894 2.3E-107 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Gene3D G3DSA:3.30.450.20 236 349 3.1E-15 T 28-03-2018 SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 474 637 1.4E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10340 abfe4ff145832a9ddf55fb3e36328c08 919 Pfam PF00563 EAL domain 655 889 2.2E-67 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS20730 955488d1757b1c0728f8db04b89ca5a8 229 Pfam PF06271 RDD family 25 146 9.3E-17 T 28-03-2018 IPR010432 RDD SmaCSM2_RS15895 55a3ceb24ab3d024d7cfbd65682a06aa 248 Gene3D G3DSA:3.40.50.1580 1 247 5.5E-41 T 28-03-2018 SmaCSM2_RS15895 55a3ceb24ab3d024d7cfbd65682a06aa 248 Pfam PF01048 Phosphorylase superfamily 6 244 2.3E-43 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SmaCSM2_RS15895 55a3ceb24ab3d024d7cfbd65682a06aa 248 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 52 92 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SmaCSM2_RS15895 55a3ceb24ab3d024d7cfbd65682a06aa 248 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 248 33.27 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SmaCSM2_RS15895 55a3ceb24ab3d024d7cfbd65682a06aa 248 SUPERFAMILY SSF53167 5 246 1.04E-75 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 SUPERFAMILY SSF53633 4 236 3.93E-74 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 Pfam PF00696 Amino acid kinase family 8 216 1.5E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 PIRSF PIRSF005650 1 241 2.7E-93 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 5.7E-98 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 45.13 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SmaCSM2_RS06635 876e5efdf3412ed9c42ec2285fc0e7e5 242 Gene3D G3DSA:3.40.1160.10 1 237 1.1E-44 T 28-03-2018 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 2 473 66.915 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 208 225 6.9E-40 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 226 242 6.9E-40 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 156 184 6.9E-40 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 132 145 6.9E-40 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 313 339 6.9E-40 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 SUPERFAMILY SSF51735 4 179 2.76E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 179 465 3.1E-94 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 PIRSF PIRSF000110 1 473 4.5E-155 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 176 5.3E-41 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 Gene3D G3DSA:3.40.50.720 1 177 5.6E-48 T 28-03-2018 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 Gene3D G3DSA:3.30.360.10 178 470 1.2E-104 T 28-03-2018 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 SUPERFAMILY SSF55347 171 465 4.58E-96 T 28-03-2018 SmaCSM2_RS08415 1bf53233c694af6eb78fc4427ffdb66e 478 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 465 1.2E-133 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 1.1E-87 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 SMART SM01232 130 222 1.1E-48 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Gene3D G3DSA:1.10.8.50 131 270 7.2E-49 T 28-03-2018 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Pfam PF06827 Zinc finger found in FPG and IleRS 242 269 1.9E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 4.3E-24 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 SMART SM00898 2 116 1.6E-53 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 SUPERFAMILY SSF57716 218 269 2.65E-15 T 28-03-2018 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 SUPERFAMILY SSF81624 2 135 6.54E-41 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 SUPERFAMILY SSF46946 131 222 3.14E-30 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Gene3D G3DSA:3.20.190.10 2 127 8.4E-38 T 28-03-2018 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.3E-33 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SmaCSM2_RS00310 20d42ff144ef0eff9cc3e12097ee1b53 270 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 44.232 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SmaCSM2_RS03820 5a1c3db279611834f76ea55fe5f70c63 219 Gene3D G3DSA:2.50.20.10 37 216 1.9E-38 T 28-03-2018 SmaCSM2_RS03820 5a1c3db279611834f76ea55fe5f70c63 219 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 4 216 23.541 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 SmaCSM2_RS03820 5a1c3db279611834f76ea55fe5f70c63 219 SUPERFAMILY SSF89392 44 214 7.45E-36 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SmaCSM2_RS03820 5a1c3db279611834f76ea55fe5f70c63 219 Pfam PF03550 Outer membrane lipoprotein LolB 58 214 1.7E-38 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 SmaCSM2_RS03820 5a1c3db279611834f76ea55fe5f70c63 219 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 9 214 1.2E-25 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 Gene3D G3DSA:1.10.287.40 2 105 2.3E-20 T 28-03-2018 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 419 6.6E-161 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 Gene3D G3DSA:3.30.930.10 106 426 1.7E-93 T 28-03-2018 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 424 39.186 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.4E-28 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 SUPERFAMILY SSF46589 1 113 1.05E-24 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 227 402 9.3E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PRINTS PR00981 Seryl-tRNA synthetase signature 278 291 7.2E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PRINTS PR00981 Seryl-tRNA synthetase signature 335 351 7.2E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PRINTS PR00981 Seryl-tRNA synthetase signature 266 278 7.2E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PRINTS PR00981 Seryl-tRNA synthetase signature 318 331 7.2E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PRINTS PR00981 Seryl-tRNA synthetase signature 353 369 7.2E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 PIRSF PIRSF001529 1 426 4.6E-167 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SmaCSM2_RS13620 c99be0d02d59b8398719c78371fa5267 426 SUPERFAMILY SSF55681 117 421 6.44E-100 T 28-03-2018 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 SUPERFAMILY SSF63411 734 926 2.33E-28 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Gene3D G3DSA:3.30.830.10 483 723 4.4E-43 T 28-03-2018 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 SUPERFAMILY SSF63411 503 714 1.34E-43 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Pfam PF05193 Peptidase M16 inactive domain 675 854 6.9E-27 T 28-03-2018 IPR007863 Peptidase M16, C-terminal SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Pfam PF05193 Peptidase M16 inactive domain 211 385 1.4E-32 T 28-03-2018 IPR007863 Peptidase M16, C-terminal SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Pfam PF00675 Insulinase (Peptidase family M16) 53 181 2.7E-14 T 28-03-2018 IPR011765 Peptidase M16, N-terminal SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Pfam PF00675 Insulinase (Peptidase family M16) 520 637 1.2E-6 T 28-03-2018 IPR011765 Peptidase M16, N-terminal SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Gene3D G3DSA:3.30.830.10 41 260 3.2E-60 T 28-03-2018 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 SUPERFAMILY SSF63411 41 256 1.26E-52 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Gene3D G3DSA:3.30.830.10 267 468 7.3E-29 T 28-03-2018 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 Gene3D G3DSA:3.30.830.10 735 933 1.2E-25 T 28-03-2018 SmaCSM2_RS00860 ead40fde96049d88343ddf92d2395e47 949 SUPERFAMILY SSF63411 274 454 2.39E-28 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 8.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 Gene3D G3DSA:1.10.10.10 1 87 5.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 Pfam PF03466 LysR substrate binding domain 92 297 7.8E-45 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 Gene3D G3DSA:3.40.190.10 92 179 3.0E-12 T 28-03-2018 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 SUPERFAMILY SSF53850 93 298 4.71E-44 T 28-03-2018 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 Gene3D G3DSA:3.40.190.10 180 267 3.0E-29 T 28-03-2018 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 SUPERFAMILY SSF46785 7 114 6.43E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS21695 720bc79bb28d3d472d439df1c3ecac3f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Pfam PF00512 His Kinase A (phospho-acceptor) domain 471 536 5.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Gene3D G3DSA:1.10.287.130 471 532 8.3E-19 T 28-03-2018 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SUPERFAMILY SSF52172 830 947 2.56E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Gene3D G3DSA:3.40.50.2300 811 945 6.4E-36 T 28-03-2018 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 583 696 1.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 657 675 9.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 694 9.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 623 637 9.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 641 651 9.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Gene3D G3DSA:1.20.120.160 946 1061 2.7E-9 T 28-03-2018 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Pfam PF00072 Response regulator receiver domain 832 939 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SUPERFAMILY SSF47226 924 1044 1.2E-14 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SMART SM00448 830 941 4.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SMART SM00387 583 697 4.7E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Gene3D G3DSA:3.30.565.10 540 706 5.6E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SMART SM00388 471 536 8.6E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SUPERFAMILY SSF47384 456 537 4.9E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SUPERFAMILY SSF55785 341 448 5.23E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Gene3D G3DSA:3.30.450.20 331 470 6.1E-10 T 28-03-2018 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 Pfam PF01627 Hpt domain 976 1056 1.3E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 SmaCSM2_RS03865 65006c94fa5fc9c981b6d57452f27c76 1075 SUPERFAMILY SSF55874 525 697 1.15E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 Gene3D G3DSA:1.10.10.10 90 162 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 SUPERFAMILY SSF88946 4 91 7.85E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 Pfam PF04542 Sigma-70 region 2 14 77 4.3E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 Pfam PF08281 Sigma-70, region 4 107 159 4.3E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 SUPERFAMILY SSF88659 98 160 3.71E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 Gene3D G3DSA:1.10.1740.10 2 80 1.5E-13 T 28-03-2018 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 159 2.8E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 159 9.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17675 afc158e1a516edb1a9d81d2d02dea13a 166 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 131 147 9.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 1 625 0.0 T 28-03-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Gene3D G3DSA:3.40.50.980 243 404 3.9E-34 T 28-03-2018 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Gene3D G3DSA:3.40.50.980 49 242 1.5E-43 T 28-03-2018 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Pfam PF00501 AMP-binding enzyme 60 501 3.8E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Pfam PF13193 AMP-binding enzyme C-terminal domain 510 590 8.5E-25 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Gene3D G3DSA:3.30.300.30 495 606 2.7E-27 T 28-03-2018 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 ProSitePatterns PS00455 Putative AMP-binding domain signature. 238 249 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 SUPERFAMILY SSF56801 2 622 8.24E-162 T 28-03-2018 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Gene3D G3DSA:2.30.38.10 405 494 8.5E-9 T 28-03-2018 SmaCSM2_RS04175 922a303e27fdfc7e628f1e4cabf0dc64 626 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 57 3.9E-25 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 4.7E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:3.40.50.300 75 205 2.4E-26 T 28-03-2018 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.4E-225 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.031 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 2.3E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF50465 300 395 1.7E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF52540 5 221 1.89E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF50447 207 303 1.14E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:2.40.30.10 302 395 2.6E-32 T 28-03-2018 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 6.0E-19 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:3.40.50.300 2 74 2.1E-10 T 28-03-2018 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03910 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:2.40.30.10 208 298 5.2E-32 T 28-03-2018 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 4.7E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:3.40.50.300 75 205 2.4E-26 T 28-03-2018 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.4E-225 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.031 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 2.3E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF50465 300 395 1.7E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF52540 5 221 1.89E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 SUPERFAMILY SSF50447 207 303 1.14E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:2.40.30.10 302 395 2.6E-32 T 28-03-2018 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 6.0E-19 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:3.40.50.300 2 74 2.1E-10 T 28-03-2018 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS03980 22713dde8246f5b6f67cef098253117e 396 Gene3D G3DSA:2.40.30.10 208 298 5.2E-32 T 28-03-2018 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Gene3D G3DSA:3.90.1580.10 337 423 6.7E-18 T 28-03-2018 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Gene3D G3DSA:3.90.1580.10 169 336 2.1E-33 T 28-03-2018 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Gene3D G3DSA:1.20.120.450 6 152 3.4E-9 T 28-03-2018 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 15 419 6.0E-161 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 SUPERFAMILY SSF56436 181 422 5.84E-63 T 28-03-2018 IPR016187 C-type lectin fold SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 SUPERFAMILY SSF109854 13 147 1.26E-7 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Pfam PF03781 Sulfatase-modifying factor enzyme 1 202 336 1.1E-20 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Pfam PF03781 Sulfatase-modifying factor enzyme 1 340 420 1.1E-8 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SmaCSM2_RS21545 b7bf8ec011200ff6560ef04d9ba49533 423 Pfam PF12867 DinB superfamily 19 150 1.1E-10 T 28-03-2018 IPR024775 DinB-like domain SmaCSM2_RS18645 b12cf6ecf780d47a6ab6f6c65cb868ec 240 SUPERFAMILY SSF52540 3 223 8.78E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18645 b12cf6ecf780d47a6ab6f6c65cb868ec 240 Gene3D G3DSA:3.40.50.300 1 227 5.8E-65 T 28-03-2018 SmaCSM2_RS18645 b12cf6ecf780d47a6ab6f6c65cb868ec 240 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS18645 b12cf6ecf780d47a6ab6f6c65cb868ec 240 SMART SM00382 32 219 9.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18645 b12cf6ecf780d47a6ab6f6c65cb868ec 240 Pfam PF00005 ABC transporter 23 171 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 Gene3D G3DSA:1.10.287.130 218 267 1.6E-10 T 28-03-2018 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 SUPERFAMILY SSF55874 274 428 1.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 6.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 6.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 6.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 Gene3D G3DSA:3.30.565.10 268 429 2.6E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 SUPERFAMILY SSF47384 210 282 2.35E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 SMART SM00387 323 432 5.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 423 1.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 SMART SM00388 227 284 2.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS19195 6f5a7f75cd56c864148ede3fe33ea999 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 282 3.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 SMART SM00965 65 116 1.2E-12 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 1023 1040 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 Pfam PF00593 TonB dependent receptor 465 1038 1.2E-32 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 SUPERFAMILY SSF56935 759 1040 8.85E-69 T 28-03-2018 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 SUPERFAMILY SSF56935 337 381 8.85E-69 T 28-03-2018 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 SUPERFAMILY SSF56935 415 622 8.85E-69 T 28-03-2018 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 SUPERFAMILY SSF56935 165 292 8.85E-69 T 28-03-2018 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 Gene3D G3DSA:2.40.170.20 327 1040 1.5E-71 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 Gene3D G3DSA:2.170.130.10 156 278 1.5E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12040 8f24506e701317d99825c0e24203a7ac 1040 Pfam PF07715 TonB-dependent Receptor Plug Domain 164 262 8.6E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 Gene3D G3DSA:1.10.287.80 239 282 4.3E-14 T 28-03-2018 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 Gene3D G3DSA:1.10.287.80 2 41 1.4E-16 T 28-03-2018 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 Pfam PF00231 ATP synthase 5 286 1.1E-96 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 4.3E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 4.3E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 4.3E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 4.3E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 SUPERFAMILY SSF52943 2 287 1.28E-93 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.876 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 Gene3D G3DSA:3.40.1380.10 42 238 6.8E-75 T 28-03-2018 SmaCSM2_RS18695 70e59546d71eb18eb7b56eab12496daf 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.4E-106 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 Gene3D G3DSA:3.40.50.720 1 142 1.9E-34 T 28-03-2018 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 Gene3D G3DSA:3.30.360.10 143 290 3.3E-42 T 28-03-2018 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 131 147 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 SUPERFAMILY SSF55347 136 290 1.55E-33 T 28-03-2018 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 6 316 30.381 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 SUPERFAMILY SSF51735 6 151 6.92E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 7 316 1.9E-96 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 SMART SM00859 7 128 8.4E-34 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SmaCSM2_RS14605 bde9860e1a597c36eded302cae0e9e0e 317 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 4.3E-29 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SUPERFAMILY SSF48452 114 207 3.29E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SMART SM00028 179 212 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SMART SM00028 320 353 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SMART SM00028 354 386 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 Gene3D G3DSA:1.25.40.10 42 175 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 Gene3D G3DSA:1.25.40.10 334 362 2.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SUPERFAMILY SSF48452 320 382 2.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 SUPERFAMILY SSF48452 179 281 2.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 Pfam PF13432 Tetratricopeptide repeat 184 227 0.0067 T 28-03-2018 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 Gene3D G3DSA:1.25.40.10 363 395 0.0023 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00035 655e719916ae28d05dccbd1dba4e52d7 397 Gene3D G3DSA:1.25.40.10 176 333 7.7E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 535 9.8E-158 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:2.20.28.20 139 162 6.2E-15 T 28-03-2018 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:2.170.220.10 163 248 1.9E-15 T 28-03-2018 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Pfam PF01588 Putative tRNA binding domain 596 690 4.0E-20 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 383 394 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 1.6E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 SUPERFAMILY SSF52374 173 385 4.65E-87 T 28-03-2018 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 SUPERFAMILY SSF52374 4 138 4.65E-87 T 28-03-2018 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 545 38.164 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:3.40.50.620 249 367 1.4E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Pfam PF09334 tRNA synthetases class I (M) 6 395 1.0E-146 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 SUPERFAMILY SSF57770 139 173 1.1E-11 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 SUPERFAMILY SSF47323 388 547 1.61E-40 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 SUPERFAMILY SSF50249 585 692 9.3E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:1.10.730.10 372 537 2.6E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:2.40.50.140 582 693 1.7E-24 T 28-03-2018 SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 Gene3D G3DSA:3.40.50.620 2 76 2.6E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15705 660c9d81bca77c22c1b0d5716bc1b7ed 693 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 569 692 5.3E-38 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 ProSitePatterns PS01219 Ammonium transporters signature. 232 257 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 PRINTS PR00342 Rhesus blood group protein signature 271 289 1.0E-8 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 PRINTS PR00342 Rhesus blood group protein signature 302 324 1.0E-8 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 PRINTS PR00342 Rhesus blood group protein signature 357 375 1.0E-8 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 PRINTS PR00342 Rhesus blood group protein signature 176 192 1.0E-8 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 Gene3D G3DSA:1.10.3430.10 68 455 6.1E-130 T 28-03-2018 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 SUPERFAMILY SSF111352 72 455 3.53E-126 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 Pfam PF00909 Ammonium Transporter Family 78 474 1.1E-122 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SmaCSM2_RS00630 f9893298b49b296fd901ba954c013f51 476 TIGRFAM TIGR00836 amt: ammonium transporter 76 474 2.4E-137 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 Gene3D G3DSA:3.40.50.300 1 286 1.7E-126 T 28-03-2018 SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 SUPERFAMILY SSF52317 290 543 3.58E-79 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 SUPERFAMILY SSF52540 2 266 4.91E-119 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 Hamap MF_01227 CTP synthase [pyrG]. 2 543 50.926 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 TIGRFAM TIGR00337 PyrG: CTP synthase 4 538 1.6E-237 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 Pfam PF06418 CTP synthase N-terminus 5 265 1.8E-123 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 Pfam PF00117 Glutamine amidotransferase class-I 303 537 1.0E-52 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS08010 4d4a125a03aa7e0df1308066d2d4d92b 554 Gene3D G3DSA:3.40.50.880 287 546 9.8E-66 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS12235 9a35e765003ef8d09cd87253adafdae8 142 SUPERFAMILY SSF55785 19 115 2.44E-28 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS12235 9a35e765003ef8d09cd87253adafdae8 142 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 116 4.6E-15 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS12235 9a35e765003ef8d09cd87253adafdae8 142 Pfam PF00989 PAS fold 20 113 4.5E-13 T 28-03-2018 IPR013767 PAS fold GO:0006355 SmaCSM2_RS12235 9a35e765003ef8d09cd87253adafdae8 142 Gene3D G3DSA:3.40.50.10600 4 132 2.1E-27 T 28-03-2018 SmaCSM2_RS12235 9a35e765003ef8d09cd87253adafdae8 142 SMART SM00091 5 73 8.0E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 Gene3D G3DSA:3.40.190.10 52 215 1.5E-34 T 28-03-2018 SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 Pfam PF12849 PBP superfamily domain 45 332 3.6E-63 T 28-03-2018 IPR024370 PBP domain SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 PIRSF PIRSF002756 4 362 3.5E-108 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 SUPERFAMILY SSF53850 53 361 2.37E-100 T 28-03-2018 SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 54 361 5.8E-124 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SmaCSM2_RS06895 4963fba15b6d438332b2e92c47d30b4a 364 Gene3D G3DSA:3.40.190.10 219 364 6.2E-25 T 28-03-2018 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 SUPERFAMILY SSF51735 7 183 5.78E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 Gene3D G3DSA:3.40.50.720 1 182 4.5E-44 T 28-03-2018 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PIRSF PIRSF000114 1 335 7.2E-97 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 9.0E-47 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 SUPERFAMILY SSF48179 182 336 7.14E-51 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 1.0E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 159 2.3E-51 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 Gene3D G3DSA:1.10.1040.10 192 340 4.2E-49 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS00725 f8b79c5cd700a9c093944dda35768f16 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 325 39.059 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 Pfam PF17092 Penicillin-binding protein OB-like domain 322 418 1.0E-12 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 Gene3D G3DSA:1.10.3810.10 52 252 3.0E-71 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 SUPERFAMILY SSF56601 417 604 1.72E-118 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 SUPERFAMILY SSF56601 268 319 1.72E-118 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 SUPERFAMILY SSF56601 660 779 1.72E-118 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 SUPERFAMILY SSF56601 216 239 1.72E-118 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 Pfam PF00905 Penicillin binding protein transpeptidase domain 424 601 1.4E-22 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 SUPERFAMILY SSF53955 47 264 2.81E-69 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 Gene3D G3DSA:3.40.710.10 254 798 9.3E-119 T 28-03-2018 SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 Pfam PF00912 Transglycosylase 59 235 1.3E-57 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS17295 c6eea3644d723e7d108bc6eea00c4e3a 807 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 69 754 3.1E-174 T 28-03-2018 SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 Gene3D G3DSA:1.10.3210.10 124 352 1.1E-28 T 28-03-2018 SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 Pfam PF08668 HDOD domain 140 268 5.5E-24 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 SUPERFAMILY SSF109604 131 344 5.65E-38 T 28-03-2018 SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 Gene3D G3DSA:3.40.50.2300 1 123 8.3E-10 T 28-03-2018 SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 PIRSF PIRSF036883 1 369 4.7E-127 T 28-03-2018 IPR014626 Signal transduction response regulator with modified HD-GYP domain, putative SmaCSM2_RS17695 3a88e46fedea9b54f880d3b188fbcd98 373 SUPERFAMILY SSF52172 2 129 1.08E-11 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS02220 4827fc739f68a261afbab93df770f5e0 538 SMART SM00052 261 505 1.3E-90 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02220 4827fc739f68a261afbab93df770f5e0 538 Gene3D G3DSA:3.20.20.450 260 516 3.2E-81 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02220 4827fc739f68a261afbab93df770f5e0 538 SUPERFAMILY SSF141868 267 513 2.62E-74 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS02220 4827fc739f68a261afbab93df770f5e0 538 Pfam PF12792 CSS motif domain associated with EAL 37 237 1.8E-35 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain SmaCSM2_RS02220 4827fc739f68a261afbab93df770f5e0 538 Pfam PF00563 EAL domain 268 500 1.9E-61 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS09940 ce891c9c8a6dbb6ebf7b11041ffb23ea 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 56 510 4.6E-146 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09940 ce891c9c8a6dbb6ebf7b11041ffb23ea 516 ProSitePatterns PS01303 BCCT family of transporters signature. 320 329 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09940 ce891c9c8a6dbb6ebf7b11041ffb23ea 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 18 509 1.0E-165 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 Pfam PF02253 Phospholipase A1 118 380 4.3E-106 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 Gene3D G3DSA:2.40.230.10 116 384 1.2E-94 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 SUPERFAMILY SSF56931 120 384 8.37E-91 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 353 373 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 170 187 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 192 208 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 260 278 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 331 348 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 295 313 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 245 259 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS14235 633280de26723ca43db3572832a1594d 384 PRINTS PR01486 Bacterial phospholipase A1 protein signature 215 234 1.3E-34 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 7 657 4.5E-265 T 28-03-2018 IPR022458 Conjugative coupling factor TraG/TraD SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 Gene3D G3DSA:3.40.50.300 164 662 1.6E-27 T 28-03-2018 SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 7 657 0.0 T 28-03-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 Pfam PF12696 TraM recognition site of TraD and TraG 509 636 2.1E-10 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 SUPERFAMILY SSF52540 399 659 1.04E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07620 5ee707cfaf36d04eca33d11be684b03e 729 SUPERFAMILY SSF52540 149 344 1.04E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Pfam PF07495 Y_Y_Y domain 687 746 5.7E-18 T 28-03-2018 IPR011123 Two component regulator three Y SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Gene3D G3DSA:2.130.10.10 57 140 5.5E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Gene3D G3DSA:2.130.10.10 147 398 1.5E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 SUPERFAMILY SSF63829 434 644 1.31E-6 T 28-03-2018 SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Gene3D G3DSA:3.30.565.10 858 995 2.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 SMART SM00387 897 990 2.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Gene3D G3DSA:2.60.40.10 672 747 4.6E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Gene3D G3DSA:2.120.10.30 425 662 6.2E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Pfam PF07730 Histidine kinase 793 856 3.5E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 Pfam PF07494 Two component regulator propeller 58 76 0.016 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 SUPERFAMILY SSF55874 865 988 2.49E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS12820 4c53e48a9314464bea5f36897181cbf2 1009 SUPERFAMILY SSF63829 143 342 1.42E-11 T 28-03-2018 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 Gene3D G3DSA:3.10.310.10 125 279 1.5E-37 T 28-03-2018 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 Gene3D G3DSA:3.10.310.10 1 124 1.1E-26 T 28-03-2018 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 6 286 8.8E-57 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 Pfam PF02567 Phenazine biosynthesis-like protein 9 280 1.1E-53 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 PIRSF PIRSF016184 1 290 1.0E-81 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS05370 0d65659578455954f1f8f7a216323515 290 SUPERFAMILY SSF54506 4 289 4.89E-67 T 28-03-2018 SmaCSM2_RS02235 4a6091655b44018624e50515056634e0 258 Pfam PF01464 Transglycosylase SLT domain 127 224 7.2E-25 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS02235 4a6091655b44018624e50515056634e0 258 Gene3D G3DSA:1.10.530.10 99 249 2.0E-45 T 28-03-2018 SmaCSM2_RS02235 4a6091655b44018624e50515056634e0 258 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 144 172 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 SmaCSM2_RS02235 4a6091655b44018624e50515056634e0 258 SUPERFAMILY SSF53955 119 247 4.69E-44 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS06355 9c9567f6ba6f4432bfabd6a146e07065 530 Gene3D G3DSA:3.40.630.10 5 526 8.1E-56 T 28-03-2018 SmaCSM2_RS06355 9c9567f6ba6f4432bfabd6a146e07065 530 SUPERFAMILY SSF53187 406 518 3.02E-56 T 28-03-2018 SmaCSM2_RS06355 9c9567f6ba6f4432bfabd6a146e07065 530 SUPERFAMILY SSF53187 287 377 3.02E-56 T 28-03-2018 SmaCSM2_RS06355 9c9567f6ba6f4432bfabd6a146e07065 530 SUPERFAMILY SSF53187 29 91 3.02E-56 T 28-03-2018 SmaCSM2_RS06355 9c9567f6ba6f4432bfabd6a146e07065 530 Pfam PF04389 Peptidase family M28 295 513 2.3E-36 T 28-03-2018 IPR007484 Peptidase M28 SmaCSM2_RS11300 8f2900cc39520d7473089391a491f70f 253 SUPERFAMILY SSF117396 9 248 4.97E-70 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS11300 8f2900cc39520d7473089391a491f70f 253 Pfam PF01904 Protein of unknown function DUF72 34 245 1.8E-53 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS11300 8f2900cc39520d7473089391a491f70f 253 Gene3D G3DSA:3.20.20.410 4 253 5.0E-71 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS10745 7c61a02b813227e8acbf5f6852080ff1 329 Pfam PF11809 Domain of unknown function (DUF3330) 261 329 6.9E-44 T 28-03-2018 IPR021767 Protein of unknown function DUF3330 SmaCSM2_RS10745 7c61a02b813227e8acbf5f6852080ff1 329 Gene3D G3DSA:3.20.20.450 9 264 4.9E-93 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10745 7c61a02b813227e8acbf5f6852080ff1 329 Pfam PF00563 EAL domain 13 245 9.8E-71 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10745 7c61a02b813227e8acbf5f6852080ff1 329 SUPERFAMILY SSF141868 13 258 5.62E-85 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10745 7c61a02b813227e8acbf5f6852080ff1 329 SMART SM00052 6 250 1.0E-126 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS04085 668c0efb6ad9c52bb22e233bcfbf76ed 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 30 146 8.6E-27 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P SmaCSM2_RS04085 668c0efb6ad9c52bb22e233bcfbf76ed 147 SUPERFAMILY SSF52080 6 146 4.19E-40 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P SmaCSM2_RS04085 668c0efb6ad9c52bb22e233bcfbf76ed 147 Gene3D G3DSA:3.100.10.10 42 147 2.7E-22 T 28-03-2018 SmaCSM2_RS04085 668c0efb6ad9c52bb22e233bcfbf76ed 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 145 8.4E-44 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04085 668c0efb6ad9c52bb22e233bcfbf76ed 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 17.005 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 Gene3D G3DSA:1.20.5.40 108 137 2.2E-17 T 28-03-2018 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 Pfam PF00239 Resolvase, N terminal domain 6 139 2.9E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 Gene3D G3DSA:1.10.10.60 139 186 4.7E-9 T 28-03-2018 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 SUPERFAMILY SSF53041 6 139 3.27E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 SMART SM00857 5 139 2.6E-47 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 SUPERFAMILY SSF46689 141 183 9.41E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 Pfam PF02796 Helix-turn-helix domain of resolvase 141 184 1.1E-12 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 SmaCSM2_RS10750 d9597f04fb083c0398bd5e2bfce639c6 186 Gene3D G3DSA:3.40.50.1390 4 107 9.8E-33 T 28-03-2018 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 SUPERFAMILY SSF49879 4 95 2.28E-14 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 Gene3D G3DSA:2.60.200.20 2 118 1.4E-12 T 28-03-2018 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 Pfam PF00437 Type II/IV secretion system protein 219 495 6.7E-83 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 SUPERFAMILY SSF52540 207 502 2.19E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 Gene3D G3DSA:3.30.450.90 215 316 1.5E-35 T 28-03-2018 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 20 97 6.0E-9 T 28-03-2018 IPR032030 YscD, cytoplasmic domain SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 SMART SM00240 22 72 7.1E-6 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SmaCSM2_RS04570 61d4a2e605b7d333ac5c80daf86720c7 574 Gene3D G3DSA:3.40.50.300 317 534 1.8E-21 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 Pfam PF13437 HlyD family secretion protein 199 278 1.5E-10 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 Pfam PF13533 Biotin-lipoyl like 44 82 4.1E-8 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 303 318 2.1E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 47 67 2.1E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 Gene3D G3DSA:1.10.287.470 103 160 2.3E-5 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 Gene3D G3DSA:2.40.50.100 190 304 0.0014 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 Gene3D G3DSA:2.40.50.100 35 96 1.1E-13 T 28-03-2018 SmaCSM2_RS07100 98967424d780b4db95136c26ea43df58 318 SUPERFAMILY SSF111369 37 104 1.09E-6 T 28-03-2018 SmaCSM2_RS13445 2070fdec910ee0207b62f8d880367da1 559 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 114 550 7.4E-108 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 SmaCSM2_RS13445 2070fdec910ee0207b62f8d880367da1 559 SUPERFAMILY SSF52540 95 545 1.43E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13445 2070fdec910ee0207b62f8d880367da1 559 Gene3D G3DSA:3.40.50.300 87 550 2.6E-40 T 28-03-2018 SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 SUPERFAMILY SSF53335 18 222 1.11E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 23 221 4.1E-53 T 28-03-2018 SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 145 160 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 17 225 34.331 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 Gene3D G3DSA:3.40.50.150 15 222 3.6E-40 T 28-03-2018 SmaCSM2_RS08065 b724974fb82d54c08685a90a9112a6d8 225 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 18 222 1.4E-58 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 SmaCSM2_RS13665 bbafaf2405c930bc6412a8bbfb598b19 334 Gene3D G3DSA:3.40.1350.10 35 150 2.1E-5 T 28-03-2018 SmaCSM2_RS13665 bbafaf2405c930bc6412a8bbfb598b19 334 Pfam PF04471 Restriction endonuclease 41 149 4.7E-10 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SmaCSM2_RS17850 31b4715f38dea35c26732c87b3531b0d 65 Pfam PF10276 Zinc-finger domain 25 61 6.8E-8 T 28-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS17850 31b4715f38dea35c26732c87b3531b0d 65 Gene3D G3DSA:2.60.260.40 9 64 3.6E-17 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Gene3D G3DSA:3.20.20.60 478 791 1.6E-104 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 694 712 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Pfam PF00391 PEP-utilising enzyme, mobile domain 384 455 5.8E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Gene3D G3DSA:3.30.470.20 195 357 8.5E-41 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 789 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 344 2.6E-111 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 414 425 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 SUPERFAMILY SSF52009 351 464 1.31E-32 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 711 726 8.5E-6 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 747 759 8.5E-6 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 694 709 8.5E-6 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Gene3D G3DSA:3.50.30.10 358 474 4.4E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 PIRSF PIRSF000854 1 792 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 SUPERFAMILY SSF56059 3 385 5.89E-102 T 28-03-2018 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Gene3D G3DSA:3.30.1490.20 1 194 4.0E-52 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 SUPERFAMILY SSF51621 462 789 2.43E-95 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS13295 f561b916f07d08ce075d75241590c868 792 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 482 788 9.3E-61 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SmaCSM2_RS12760 781b27acc2173595790a1cfff04a783b 153 Pfam PF12266 Protein of unknown function (DUF3613) 89 140 1.4E-12 T 28-03-2018 IPR022053 Protein of unknown function DUF3613 SmaCSM2_RS05000 488a2a7404dbaa805ec946f4b3aa4c33 70 Pfam PF14117 Domain of unknown function (DUF4287) 9 66 1.0E-26 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 SmaCSM2_RS14350 02a843178ce1ba6a20d4ca6a26982689 116 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 21 110 2.5E-27 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SmaCSM2_RS14350 02a843178ce1ba6a20d4ca6a26982689 116 Gene3D G3DSA:3.30.1360.20 15 115 6.5E-29 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SmaCSM2_RS14350 02a843178ce1ba6a20d4ca6a26982689 116 SUPERFAMILY SSF55248 21 114 9.03E-32 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SmaCSM2_RS14350 02a843178ce1ba6a20d4ca6a26982689 116 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 19 112 24.108 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 SUPERFAMILY SSF55021 97 185 7.4E-19 T 28-03-2018 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 SUPERFAMILY SSF55021 11 91 1.42E-9 T 28-03-2018 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 Gene3D G3DSA:3.30.70.260 28 95 1.6E-4 T 28-03-2018 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 Gene3D G3DSA:3.30.70.260 97 185 4.2E-13 T 28-03-2018 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 Pfam PF13740 ACT domain 14 87 1.0E-14 T 28-03-2018 SmaCSM2_RS08305 514ee5eff02a1f3b93053d516bfc8927 186 PIRSF PIRSF028103 11 186 3.5E-71 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 SmaCSM2_RS01245 71a8d52a65ba794f781a683c253698f1 440 Gene3D G3DSA:1.20.120.20 3 166 0.0014 T 28-03-2018 SmaCSM2_RS01245 71a8d52a65ba794f781a683c253698f1 440 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 232 301 5.7E-19 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal SmaCSM2_RS01245 71a8d52a65ba794f781a683c253698f1 440 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 104 171 5.5E-13 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal SmaCSM2_RS01245 71a8d52a65ba794f781a683c253698f1 440 Gene3D G3DSA:1.20.120.20 177 424 0.011 T 28-03-2018 SmaCSM2_RS14595 aa19df5fec18d8320ae74cd018c2262a 87 Pfam PF03795 YCII-related domain 6 85 5.1E-8 T 28-03-2018 IPR005545 YCII-related SmaCSM2_RS14595 aa19df5fec18d8320ae74cd018c2262a 87 SUPERFAMILY SSF54909 5 85 9.65E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS14595 aa19df5fec18d8320ae74cd018c2262a 87 Gene3D G3DSA:3.30.70.1060 1 87 3.4E-14 T 28-03-2018 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 Pfam PF00593 TonB dependent receptor 246 712 7.0E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 SUPERFAMILY SSF56935 28 713 1.52E-111 T 28-03-2018 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 713 2.3E-75 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 Gene3D G3DSA:2.40.170.20 171 713 1.8E-62 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 Gene3D G3DSA:2.170.130.10 28 165 2.9E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 158 1.7E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13495 43f97c6e34f1e4589716fbec8026b500 713 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 696 713 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 ProSitePatterns PS00177 DNA topoisomerase II signature. 438 446 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 751 767 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 44 59 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 541 553 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 128 142 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 503 519 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 436 450 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 284 297 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 79 92 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR00418 DNA topoisomerase II family signature 521 538 6.1E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SUPERFAMILY SSF55874 13 234 2.1E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 819 98.017 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Gene3D G3DSA:3.30.230.10 241 408 7.8E-64 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SUPERFAMILY SSF54211 237 407 2.28E-58 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Pfam PF00204 DNA gyrase B 237 406 3.9E-59 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 748 808 2.0E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 819 8.6E-295 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Pfam PF01751 Toprim domain 435 542 1.1E-17 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SUPERFAMILY SSF56719 410 576 5.23E-84 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SUPERFAMILY SSF56719 745 810 5.23E-84 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Gene3D G3DSA:3.40.50.670 416 816 1.3E-104 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SMART SM00433 44 812 2.9E-257 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 211 224 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 390 410 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 772 784 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 376 390 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 236 258 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 328 344 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 486 495 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 788 804 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 14 24 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 PRINTS PR01159 DNA gyrase subunit B signature 196 211 8.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 186 5.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 Gene3D G3DSA:3.30.565.10 12 240 5.5E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00020 78d2652d08e20c8293cc0fd759cc0cfc 819 SMART SM00387 40 190 1.7E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00655 2a37eded39bdf4adaa44db2e521d86ac 104 ProSitePatterns PS00018 EF-hand calcium-binding domain. 77 89 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:1.50.10.20 1144 1423 2.2E-23 T 28-03-2018 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:2.60.40.10 286 356 0.27 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 280 374 3.1E-23 T 28-03-2018 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 PIRSF PIRSF038980 26 1634 0.0 T 28-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 742 884 6.4E-15 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 SUPERFAMILY SSF48239 1148 1407 1.66E-30 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 SMART SM01359 741 884 2.5E-32 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:2.60.40.10 839 997 0.25 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:2.60.40.10 1497 1607 0.53 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 SMART SM01360 948 1037 1.4E-24 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Pfam PF01835 MG2 domain 380 467 3.0E-20 T 28-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:2.60.40.10 383 476 6.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Gene3D G3DSA:2.60.120.430 1002 1112 8.4E-5 T 28-03-2018 SmaCSM2_RS16170 5947d756b07b174a9915bd873306d03b 1635 Pfam PF00207 Alpha-2-macroglobulin family 955 1036 8.7E-8 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SMART SM00267 413 568 2.1E-15 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 174 293 2.6E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 298 420 6.1E-17 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SUPERFAMILY SSF55781 21 156 1.61E-20 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Pfam PF00990 Diguanylate cyclase, GGDEF domain 426 562 7.6E-22 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Gene3D G3DSA:3.30.450.20 299 419 5.0E-24 T 28-03-2018 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Gene3D G3DSA:3.30.450.20 175 298 1.9E-14 T 28-03-2018 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SUPERFAMILY SSF55785 287 411 4.34E-19 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Gene3D G3DSA:3.30.450.40 2 174 3.8E-22 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Pfam PF01590 GAF domain 21 147 6.7E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Pfam PF08448 PAS fold 315 414 5.2E-7 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 Gene3D G3DSA:3.30.70.270 420 565 5.2E-31 T 28-03-2018 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SUPERFAMILY SSF55073 429 560 5.65E-26 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SUPERFAMILY SSF55785 164 288 8.17E-12 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SMART SM00065 19 163 0.0034 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 421 562 2.3E-23 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS11670 8ab608cb175abc06ae22b092cc85a40a 569 SMART SM00091 302 368 3.2E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06905 5f5654e82913e7601c263a876c1cddca 410 SUPERFAMILY SSF56935 98 402 1.07E-25 T 28-03-2018 SmaCSM2_RS06905 5f5654e82913e7601c263a876c1cddca 410 Gene3D G3DSA:2.40.160.10 64 409 1.9E-35 T 28-03-2018 SmaCSM2_RS02815 0bbb3d29ca66531653a9614aa74fbb91 195 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 12 190 2.5E-33 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SmaCSM2_RS02815 0bbb3d29ca66531653a9614aa74fbb91 195 Gene3D G3DSA:2.60.120.590 5 195 1.8E-50 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SmaCSM2_RS02815 0bbb3d29ca66531653a9614aa74fbb91 195 SUPERFAMILY SSF51197 5 193 2.84E-62 T 28-03-2018 SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 Gene3D G3DSA:3.40.50.720 17 257 4.3E-40 T 28-03-2018 SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 Pfam PF00106 short chain dehydrogenase 22 214 2.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS07205 3e81754e47cb0885e35ee3a3494d2b5c 258 SUPERFAMILY SSF51735 17 253 4.15E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS19690 70294b1d649c252df48db5dcfd98fe47 264 SUPERFAMILY SSF51366 12 262 2.0E-92 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS19690 70294b1d649c252df48db5dcfd98fe47 264 Gene3D G3DSA:3.20.20.70 11 264 7.0E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS19690 70294b1d649c252df48db5dcfd98fe47 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 36.906 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SmaCSM2_RS19690 70294b1d649c252df48db5dcfd98fe47 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 1.8E-98 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SmaCSM2_RS19690 70294b1d649c252df48db5dcfd98fe47 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 SmaCSM2_RS11340 ec8674ff3e80cc41cd2477aa9452c642 277 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS11340 ec8674ff3e80cc41cd2477aa9452c642 277 Pfam PF00005 ABC transporter 39 177 4.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS11340 ec8674ff3e80cc41cd2477aa9452c642 277 SMART SM00382 47 227 1.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11340 ec8674ff3e80cc41cd2477aa9452c642 277 SUPERFAMILY SSF52540 22 245 8.83E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11340 ec8674ff3e80cc41cd2477aa9452c642 277 Gene3D G3DSA:3.40.50.300 18 251 1.0E-66 T 28-03-2018 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 Gene3D G3DSA:1.20.1560.10 22 348 7.1E-39 T 28-03-2018 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 SUPERFAMILY SSF90123 20 340 4.32E-51 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 Gene3D G3DSA:3.40.50.300 349 605 1.0E-74 T 28-03-2018 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 SUPERFAMILY SSF52540 350 601 1.26E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 Pfam PF00664 ABC transporter transmembrane region 42 302 5.9E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 Pfam PF00005 ABC transporter 380 531 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS06490 0a4284e075bad791a570b58f6ce74ab9 610 SMART SM00382 386 577 2.2E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS13650 08954cd487999c89c4fcf851fbd67573 268 SMART SM00240 137 187 7.1E-7 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SmaCSM2_RS13650 08954cd487999c89c4fcf851fbd67573 268 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 125 208 2.1E-14 T 28-03-2018 IPR032030 YscD, cytoplasmic domain SmaCSM2_RS13650 08954cd487999c89c4fcf851fbd67573 268 Gene3D G3DSA:3.10.290.10 62 93 0.053 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS13650 08954cd487999c89c4fcf851fbd67573 268 Gene3D G3DSA:2.60.200.20 113 235 5.4E-19 T 28-03-2018 SmaCSM2_RS13650 08954cd487999c89c4fcf851fbd67573 268 SUPERFAMILY SSF49879 120 209 9.74E-18 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SmaCSM2_RS03720 ace2fe675d0564fef4ec76672f5f43b7 153 Gene3D G3DSA:1.10.3680.10 81 145 9.5E-4 T 28-03-2018 IPR029024 TerB-like SmaCSM2_RS03720 ace2fe675d0564fef4ec76672f5f43b7 153 Pfam PF11304 Protein of unknown function (DUF3106) 43 141 1.5E-26 T 28-03-2018 IPR021455 Protein of unknown function DUF3106 SmaCSM2_RS19185 97cce8992609d2f129787263d39dbd7d 246 SUPERFAMILY SSF48371 53 245 3.72E-36 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SmaCSM2_RS19185 97cce8992609d2f129787263d39dbd7d 246 Gene3D G3DSA:1.25.40.70 7 132 0.0045 T 28-03-2018 SmaCSM2_RS19185 97cce8992609d2f129787263d39dbd7d 246 Pfam PF08713 DNA alkylation repair enzyme 140 244 6.1E-9 T 28-03-2018 IPR014825 DNA alkylation repair enzyme SmaCSM2_RS19185 97cce8992609d2f129787263d39dbd7d 246 Gene3D G3DSA:1.25.40.290 138 246 3.2E-21 T 28-03-2018 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SMART SM00387 368 479 4.6E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 478 7.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Gene3D G3DSA:3.30.450.20 26 185 3.4E-22 T 28-03-2018 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 321 5.6E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SMART SM00388 258 323 5.2E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Gene3D G3DSA:3.30.565.10 328 485 3.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 3.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 3.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 3.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 3.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Gene3D G3DSA:1.10.287.130 242 318 1.2E-10 T 28-03-2018 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 Pfam PF00672 HAMP domain 208 254 1.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SMART SM00304 207 258 2.0E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SUPERFAMILY SSF55874 312 480 1.26E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SUPERFAMILY SSF47384 249 322 2.55E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06340 53a182f7689fd79984338e4358662cea 486 SUPERFAMILY SSF103190 79 180 6.67E-9 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SmaCSM2_RS15340 a9e66f1717555404892abad98a07ef48 501 Pfam PF05872 Bacterial protein of unknown function (DUF853) 14 501 2.7E-218 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal SmaCSM2_RS15340 a9e66f1717555404892abad98a07ef48 501 Gene3D G3DSA:3.40.50.300 5 368 3.3E-28 T 28-03-2018 SmaCSM2_RS15340 a9e66f1717555404892abad98a07ef48 501 SUPERFAMILY SSF52540 3 385 1.0E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 SUPERFAMILY SSF63418 5 99 4.05E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 5 486 33.378 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 416 6.1E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Gene3D G3DSA:3.40.1190.10 101 335 3.6E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 23 486 2.1E-144 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 SUPERFAMILY SSF53244 333 487 3.79E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Pfam PF01225 Mur ligase family, catalytic domain 24 97 8.5E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Gene3D G3DSA:3.40.1390.10 4 100 8.9E-18 T 28-03-2018 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Pfam PF08245 Mur ligase middle domain 110 311 3.9E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 SUPERFAMILY SSF53623 101 332 3.79E-75 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03240 a1448f8500772718820b30f101917870 502 Gene3D G3DSA:3.90.190.20 336 490 1.6E-44 T 28-03-2018 SmaCSM2_RS02325 5a209e88081b27a677f6d72eaa95ff02 309 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 50 267 5.2E-48 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 Pfam PF00155 Aminotransferase class I and II 29 394 1.8E-80 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 SUPERFAMILY SSF53383 2 397 2.32E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 Gene3D G3DSA:3.90.1150.10 310 398 8.3E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 Gene3D G3DSA:3.90.1150.10 2 86 1.5E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 PRINTS PR00799 Aspartate aminotransferase signature 276 301 1.4E-35 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 PRINTS PR00799 Aspartate aminotransferase signature 177 196 1.4E-35 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 PRINTS PR00799 Aspartate aminotransferase signature 208 220 1.4E-35 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 PRINTS PR00799 Aspartate aminotransferase signature 343 361 1.4E-35 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 SmaCSM2_RS00195 427152e73075b7e83c9e75b787001277 400 Gene3D G3DSA:3.40.640.10 92 309 3.6E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS01260 4b2a743a23ab081e9e979e255212d4b9 231 Pfam PF05100 Phage minor tail protein L 24 228 5.0E-77 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail SmaCSM2_RS01260 4b2a743a23ab081e9e979e255212d4b9 231 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 5 227 8.7E-88 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 Gene3D G3DSA:3.50.50.60 3 131 2.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 139 159 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 Gene3D G3DSA:3.50.50.60 262 323 8.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 SUPERFAMILY SSF51905 6 316 6.8E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 300 3.6E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 9.4E-38 T 28-03-2018 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 9.4E-38 T 28-03-2018 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 9.4E-38 T 28-03-2018 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 9.4E-38 T 28-03-2018 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 9.4E-38 T 28-03-2018 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 44 59 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 3.6E-74 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 11 316 1.6E-118 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 SmaCSM2_RS10440 3e31f6b9e03d2a2b228521f50d04c1d2 323 Gene3D G3DSA:3.50.50.60 132 246 5.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18030 b883e9d3e1a00160e84029dfe41dbcc1 276 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 4 274 1.1E-128 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 SmaCSM2_RS18030 b883e9d3e1a00160e84029dfe41dbcc1 276 Gene3D G3DSA:3.40.50.1820 1 275 2.3E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18030 b883e9d3e1a00160e84029dfe41dbcc1 276 Pfam PF00756 Putative esterase 21 268 3.2E-69 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SmaCSM2_RS18030 b883e9d3e1a00160e84029dfe41dbcc1 276 SUPERFAMILY SSF53474 1 274 3.62E-93 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12395 b5c92691d7ad99f9a24f8605dea5c37b 167 SMART SM00226 3 139 1.9E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS12395 b5c92691d7ad99f9a24f8605dea5c37b 167 Gene3D G3DSA:3.40.50.2300 1 139 4.3E-33 T 28-03-2018 SmaCSM2_RS12395 b5c92691d7ad99f9a24f8605dea5c37b 167 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 137 1.9E-18 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS12395 b5c92691d7ad99f9a24f8605dea5c37b 167 SUPERFAMILY SSF52788 4 139 1.83E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 32 209 4.6E-53 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 Gene3D G3DSA:3.40.50.150 11 211 3.9E-32 T 28-03-2018 SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 SUPERFAMILY SSF53335 24 208 3.75E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 PIRSF PIRSF003078 8 212 7.2E-66 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 Pfam PF02527 rRNA small subunit methyltransferase G 31 207 1.3E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SmaCSM2_RS21350 8b9476a8086a47a23fac4660259499b8 212 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 20 208 26.218 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SmaCSM2_RS00340 34217921370389f797072e014b58ab88 174 SUPERFAMILY SSF55729 3 153 9.01E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS00340 34217921370389f797072e014b58ab88 174 Pfam PF13302 Acetyltransferase (GNAT) domain 8 149 5.3E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS00340 34217921370389f797072e014b58ab88 174 Gene3D G3DSA:3.40.630.30 1 163 7.2E-21 T 28-03-2018 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 PRINTS PR00982 Lysyl-tRNA synthetase signature 24 34 2.2E-6 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 218 2.2E-6 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 PRINTS PR00982 Lysyl-tRNA synthetase signature 92 109 2.2E-6 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 9 312 6.3E-111 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 Pfam PF00152 tRNA synthetases class II (D, K and N) 7 313 1.1E-33 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 Gene3D G3DSA:3.30.930.10 5 317 2.6E-54 T 28-03-2018 SmaCSM2_RS13860 a561cc7aaa1f7b7e1c381c4e71b6cda7 318 SUPERFAMILY SSF55681 7 313 2.7E-66 T 28-03-2018 SmaCSM2_RS01805 c5eb653c4096763ddd3deeae99969e37 72 Pfam PF11137 Protein of unknown function (DUF2909) 8 65 2.8E-20 T 28-03-2018 IPR021313 Protein of unknown function DUF2909 SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 217 27.798 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 SUPERFAMILY SSF52374 1 219 2.2E-47 T 28-03-2018 SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 Pfam PF01467 Cytidylyltransferase-like 6 167 5.8E-26 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 6.6E-11 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 Gene3D G3DSA:3.40.50.620 2 218 7.9E-50 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS15615 3ff0683d4c2a03cdada192722abc09af 221 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 216 3.0E-42 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SmaCSM2_RS05020 b1b272b49a19a14f6d590b2e4a5b4d7e 181 SUPERFAMILY SSF48150 4 168 3.66E-53 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SmaCSM2_RS05020 b1b272b49a19a14f6d590b2e4a5b4d7e 181 Pfam PF03352 Methyladenine glycosylase 12 120 2.4E-40 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SmaCSM2_RS05020 b1b272b49a19a14f6d590b2e4a5b4d7e 181 Gene3D G3DSA:1.10.340.30 3 130 2.4E-44 T 28-03-2018 SmaCSM2_RS13420 75d20fda3b683f6c48a05aa6b7924064 347 Gene3D G3DSA:3.40.50.300 127 338 1.4E-14 T 28-03-2018 SmaCSM2_RS13420 75d20fda3b683f6c48a05aa6b7924064 347 SUPERFAMILY SSF52540 10 325 4.42E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13420 75d20fda3b683f6c48a05aa6b7924064 347 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 29 337 6.4E-131 T 28-03-2018 IPR014155 Type IV secretion system protein VirB11 GO:0005737|GO:0006810|GO:0009405 SmaCSM2_RS13420 75d20fda3b683f6c48a05aa6b7924064 347 Gene3D G3DSA:3.30.450.90 16 125 8.0E-22 T 28-03-2018 SmaCSM2_RS13420 75d20fda3b683f6c48a05aa6b7924064 347 Pfam PF00437 Type II/IV secretion system protein 27 325 1.5E-54 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS05655 27bac3837748d65bac37f058ac7b0819 315 SUPERFAMILY SSF53590 1 314 1.44E-85 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS05655 27bac3837748d65bac37f058ac7b0819 315 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 306 4.0E-76 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS05655 27bac3837748d65bac37f058ac7b0819 315 Gene3D G3DSA:3.90.245.10 2 315 7.0E-92 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS08275 80df1d83798bea955e364f17a7f49b0d 308 PIRSF PIRSF037442 1 285 1.3E-56 T 28-03-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 SmaCSM2_RS08275 80df1d83798bea955e364f17a7f49b0d 308 SUPERFAMILY SSF53474 10 277 8.92E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08275 80df1d83798bea955e364f17a7f49b0d 308 Pfam PF12146 Serine aminopeptidase, S33 28 168 2.0E-13 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS08275 80df1d83798bea955e364f17a7f49b0d 308 Gene3D G3DSA:3.40.50.1820 10 287 1.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13585 df97224b7ff37aee73560bad2fd617df 86 Pfam PF13683 Integrase core domain 2 48 4.4E-8 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS04900 3d55af41195eeb652c634673d30dd86b 287 SUPERFAMILY SSF103481 43 141 7.85E-10 T 28-03-2018 SmaCSM2_RS04900 3d55af41195eeb652c634673d30dd86b 287 SUPERFAMILY SSF103481 182 285 2.09E-10 T 28-03-2018 SmaCSM2_RS04900 3d55af41195eeb652c634673d30dd86b 287 Pfam PF00892 EamA-like transporter family 149 280 2.3E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS04900 3d55af41195eeb652c634673d30dd86b 287 Pfam PF00892 EamA-like transporter family 6 134 5.0E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 821 909 5.6E-22 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 474 503 3.8 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 824 853 3800.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 1041 1070 0.061 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 687 722 2300.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 342 371 0.0052 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 375 405 5.7 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 306 338 78.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 237 266 1200.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 726 755 1600.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 759 788 0.012 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 406 437 950.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 890 919 0.34 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 441 470 0.0038 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 923 952 0.73 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 507 538 740.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 956 993 600.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 857 886 0.74 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SMART SM00248 274 303 330.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 595 698 2.8E-4 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.20.120.660 387 461 5.5E-17 T 28-03-2018 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 462 564 2.2E-20 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SUPERFAMILY SSF48403 702 1093 1.87E-57 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 321 386 9.0E-21 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 910 1012 4.9E-16 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 235 320 1.1E-11 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Pfam PF00023 Ankyrin repeat 1042 1072 0.0053 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Pfam PF00023 Ankyrin repeat 444 472 0.0013 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Pfam PF12796 Ankyrin repeats (3 copies) 863 952 8.7E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Pfam PF12796 Ankyrin repeats (3 copies) 321 401 7.6E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Pfam PF12796 Ankyrin repeats (3 copies) 708 789 4.0E-6 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 1015 1095 3.0E-13 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 SUPERFAMILY SSF48403 241 562 7.17E-47 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21045 741dbff4cd5a5390be5247f4858109bf 1112 Gene3D G3DSA:1.25.40.20 699 819 8.0E-25 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:3.40.50.300 463 677 7.5E-5 T 28-03-2018 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:1.25.40.10 309 437 2.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:1.25.40.10 3 55 1.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:1.25.40.10 132 220 1.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:1.25.40.10 221 307 1.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Pfam PF13181 Tetratricopeptide repeat 169 200 0.06 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SMART SM00028 100 133 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SMART SM00028 134 167 450.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SMART SM00028 271 304 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SMART SM00028 168 201 0.0046 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SMART SM00028 32 65 0.003 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 SUPERFAMILY SSF48452 5 310 2.84E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Pfam PF13432 Tetratricopeptide repeat 210 269 1.1E-4 T 28-03-2018 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Pfam PF13432 Tetratricopeptide repeat 104 167 1.5E-4 T 28-03-2018 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Pfam PF13432 Tetratricopeptide repeat 383 432 0.01 T 28-03-2018 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Pfam PF14559 Tetratricopeptide repeat 44 103 7.7E-8 T 28-03-2018 SmaCSM2_RS00595 ae36ba7b287ddbeef61ccbd24e56cd28 689 Gene3D G3DSA:1.25.40.10 56 131 1.5E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS05695 962adc28c3cc14f46976bfaf637484a3 302 Pfam PF01039 Carboxyl transferase domain 14 194 5.3E-15 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SmaCSM2_RS05695 962adc28c3cc14f46976bfaf637484a3 302 Gene3D G3DSA:3.90.226.10 3 278 3.5E-36 T 28-03-2018 SmaCSM2_RS05695 962adc28c3cc14f46976bfaf637484a3 302 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 7 276 2.1E-113 T 28-03-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 SmaCSM2_RS05695 962adc28c3cc14f46976bfaf637484a3 302 SUPERFAMILY SSF52096 6 222 9.45E-35 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS09135 cda410d593a2ee22de5407944078f7ca 191 Gene3D G3DSA:3.40.50.1000 59 186 1.3E-13 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09135 cda410d593a2ee22de5407944078f7ca 191 SUPERFAMILY SSF56784 28 168 3.96E-14 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09135 cda410d593a2ee22de5407944078f7ca 191 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 59 160 3.8E-9 T 28-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 Pfam PF02080 TrkA-C domain 246 313 3.4E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 Pfam PF02080 TrkA-C domain 338 393 8.1E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 SUPERFAMILY SSF116726 330 414 2.62E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 Gene3D G3DSA:3.30.70.1450 243 323 5.6E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 Gene3D G3DSA:3.30.70.1450 333 413 1.2E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 Pfam PF03600 Citrate transporter 23 563 7.1E-43 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SmaCSM2_RS17040 62cf71c036c338ccfa3bd5833b5d6318 615 SUPERFAMILY SSF116726 240 313 9.55E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SmaCSM2_RS00570 5eb3dd450ce43278336af37f89dc3ef4 205 Pfam PF04264 YceI-like domain 42 197 1.8E-17 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS00570 5eb3dd450ce43278336af37f89dc3ef4 205 Gene3D G3DSA:2.40.128.110 33 202 1.2E-21 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS00570 5eb3dd450ce43278336af37f89dc3ef4 205 SUPERFAMILY SSF101874 41 200 3.79E-25 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS00570 5eb3dd450ce43278336af37f89dc3ef4 205 SMART SM00867 40 200 4.1E-14 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 9.4E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 9.4E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 9.4E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 9.4E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 Pfam PF12697 Alpha/beta hydrolase family 14 249 4.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 Gene3D G3DSA:3.40.50.1820 2 264 2.1E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS09980 ebc7df8112c38502c9558871692c4754 267 SUPERFAMILY SSF53474 6 260 1.68E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 Pfam PF12833 Helix-turn-helix domain 202 280 1.9E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 233 274 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 Pfam PF02311 AraC-like ligand binding domain 50 152 6.4E-7 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 Gene3D G3DSA:1.10.10.60 177 233 3.8E-12 T 28-03-2018 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 SUPERFAMILY SSF51182 36 210 2.31E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 Gene3D G3DSA:2.60.120.10 8 112 3.7E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 Gene3D G3DSA:1.10.10.60 234 283 3.5E-13 T 28-03-2018 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 SUPERFAMILY SSF46689 233 280 3.05E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 SMART SM00342 196 278 1.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 1.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS06745 af4491fec060dfaf28bf660636ea0e6e 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 1.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 SUPERFAMILY SSF52540 366 497 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 SUPERFAMILY SSF52540 156 290 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 SUPERFAMILY SSF52540 21 102 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 Gene3D G3DSA:3.40.50.300 533 881 2.1E-53 T 28-03-2018 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 Gene3D G3DSA:3.40.50.300 8 42 0.21 T 28-03-2018 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 Gene3D G3DSA:3.40.50.300 43 57 0.16 T 28-03-2018 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 ProSitePatterns PS00211 ABC transporters family signature. 769 783 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 Gene3D G3DSA:1.20.1580.10 106 415 1.2E-60 T 28-03-2018 SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 SUPERFAMILY SSF52540 623 853 1.87E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11210 9fac0cb5386600e770099a1b1c059481 882 SUPERFAMILY SSF52540 544 586 1.87E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SUPERFAMILY SSF55874 595 738 3.01E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Gene3D G3DSA:3.30.450.40 127 312 9.5E-37 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 739 5.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SMART SM00065 146 324 1.3E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Pfam PF01590 GAF domain 147 312 5.5E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SUPERFAMILY SSF55781 131 311 7.41E-55 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Pfam PF08446 PAS fold 15 118 3.0E-9 T 28-03-2018 IPR013654 PAS fold-2 GO:0006355 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Gene3D G3DSA:3.30.450.20 3 119 3.8E-6 T 28-03-2018 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Pfam PF00360 Phytochrome region 327 504 9.4E-54 T 28-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SUPERFAMILY SSF55781 297 501 1.57E-50 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SUPERFAMILY SSF47384 505 587 2.94E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SMART SM00387 629 741 3.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 PRINTS PR01033 Phytochrome signature 346 366 1.9E-18 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 PRINTS PR01033 Phytochrome signature 161 180 1.9E-18 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 PRINTS PR01033 Phytochrome signature 432 451 1.9E-18 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 PRINTS PR01033 Phytochrome signature 248 269 1.9E-18 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 PRINTS PR01033 Phytochrome signature 463 481 1.9E-18 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Pfam PF00512 His Kinase A (phospho-acceptor) domain 522 586 3.8E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Gene3D G3DSA:1.10.287.130 510 584 1.2E-12 T 28-03-2018 SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 Gene3D G3DSA:3.30.565.10 592 744 9.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SUPERFAMILY SSF55785 6 117 8.37E-18 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10605 52c4d0651d6b9d1d4badced10b0a9c75 745 SMART SM00388 520 588 5.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 Gene3D G3DSA:2.170.130.10 34 177 3.6E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 SUPERFAMILY SSF56935 33 756 2.11E-104 T 28-03-2018 SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 51 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 Gene3D G3DSA:2.40.170.20 178 756 5.1E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 167 5.9E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00270 f15bc439bd0c0c1408b59db01c10b46c 756 Pfam PF00593 TonB dependent receptor 293 754 2.5E-34 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 Gene3D G3DSA:3.30.420.40 165 199 5.3E-4 T 28-03-2018 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 1.7E-158 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 SMART SM00268 10 345 0.004 T 28-03-2018 IPR004000 Actin family SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 SUPERFAMILY SSF53067 155 340 4.92E-49 T 28-03-2018 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 Gene3D G3DSA:3.90.640.10 200 257 1.2E-27 T 28-03-2018 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 Gene3D G3DSA:3.30.420.40 258 322 1.3E-8 T 28-03-2018 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 8.3E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 8.3E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 8.3E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 8.3E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 8.3E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 Pfam PF06723 MreB/Mbl protein 11 339 2.1E-149 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 SUPERFAMILY SSF53067 9 153 1.04E-37 T 28-03-2018 SmaCSM2_RS18380 799157e17f85cb28363a712ceb5f24ba 348 Gene3D G3DSA:3.30.420.40 8 164 1.5E-43 T 28-03-2018 SmaCSM2_RS14400 6e2be71f1db028571d818e7ad3872ac4 534 Pfam PF10091 Putative glucoamylase 224 470 9.2E-88 T 28-03-2018 IPR019282 Domain of unknown function DUF2329 SmaCSM2_RS14400 6e2be71f1db028571d818e7ad3872ac4 534 PIRSF PIRSF028431 5 498 5.7E-204 T 28-03-2018 IPR016883 Uncharacterised conserved protein UCP028431 SmaCSM2_RS11580 4545ef53074c6f7bc37cb46be5849655 88 Pfam PF11747 Killing trait 11 77 5.2E-27 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS05500 d6c549ceeee9b071c863bcdbf8a1c11c 287 Pfam PF01261 Xylose isomerase-like TIM barrel 49 234 9.6E-12 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05500 d6c549ceeee9b071c863bcdbf8a1c11c 287 Gene3D G3DSA:3.20.20.150 21 280 5.1E-37 T 28-03-2018 SmaCSM2_RS05500 d6c549ceeee9b071c863bcdbf8a1c11c 287 SUPERFAMILY SSF51658 35 277 8.02E-37 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 Gene3D G3DSA:3.40.50.300 21 46 0.095 T 28-03-2018 SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 Gene3D G3DSA:3.40.50.300 538 883 2.1E-51 T 28-03-2018 SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 SUPERFAMILY SSF52540 623 853 2.8E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 SUPERFAMILY SSF52540 545 586 2.8E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 SUPERFAMILY SSF52540 20 102 5.82E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 SUPERFAMILY SSF52540 156 290 5.82E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 SUPERFAMILY SSF52540 358 497 5.82E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 Gene3D G3DSA:1.20.1580.10 120 415 2.1E-61 T 28-03-2018 SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 Gene3D G3DSA:3.40.50.300 47 119 0.32 T 28-03-2018 SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS20255 3fcfe31e85c6d2da48cc1b75e9578fc0 883 ProSitePatterns PS00211 ABC transporters family signature. 769 783 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS03185 359d12a08cef86e9b7abb0aff538b7e7 202 Pfam PF00999 Sodium/hydrogen exchanger family 4 195 2.6E-6 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS03185 359d12a08cef86e9b7abb0aff538b7e7 202 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 186 1.3E-26 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 PIRSF PIRSF001259 26 378 2.1E-83 T 28-03-2018 SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 Pfam PF00925 GTP cyclohydrolase II 182 343 1.7E-49 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 Gene3D G3DSA:3.90.870.10 23 91 0.01 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 SUPERFAMILY SSF142695 189 345 4.45E-48 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 Gene3D G3DSA:3.40.250.10 201 290 0.043 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS19010 50f4b3dec20d946560f2321f20c9b2d8 378 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 174 370 38.027 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SmaCSM2_RS01060 766bb7a8deaa3b5a5e81ab4014e4be5f 481 Gene3D G3DSA:3.60.10.10 181 480 3.5E-30 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS01060 766bb7a8deaa3b5a5e81ab4014e4be5f 481 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 211 445 9.8E-8 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS01060 766bb7a8deaa3b5a5e81ab4014e4be5f 481 SUPERFAMILY SSF56219 178 480 1.44E-30 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS12400 f206bbea2ec1e970f2abfbcd2dcaaaa1 343 Pfam PF01758 Sodium Bile acid symporter family 47 242 4.0E-37 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SmaCSM2_RS12400 f206bbea2ec1e970f2abfbcd2dcaaaa1 343 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 329 1.8E-115 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SmaCSM2_RS12400 f206bbea2ec1e970f2abfbcd2dcaaaa1 343 PIRSF PIRSF005508 1 342 1.5E-116 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 926 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:3.40.50.300 8 36 0.0016 T 28-03-2018 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 ProSitePatterns PS00211 ABC transporters family signature. 831 845 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 941 22.523 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 SUPERFAMILY SSF52540 616 915 1.27E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:3.40.50.300 610 952 5.4E-54 T 28-03-2018 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:3.30.190.20 129 250 4.6E-41 T 28-03-2018 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 SUPERFAMILY SSF52540 3 206 4.36E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 SUPERFAMILY SSF52540 432 571 4.36E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:3.40.50.300 37 116 2.1E-4 T 28-03-2018 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:1.10.8.280 289 407 1.9E-37 T 28-03-2018 SmaCSM2_RS05885 575bc4a484e718efd3df48f1981e2f07 997 Gene3D G3DSA:3.40.50.300 459 608 8.8E-24 T 28-03-2018 SmaCSM2_RS00775 5b9518204c2676f2c7c495bb3bdb0da7 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 116 6.5E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS00775 5b9518204c2676f2c7c495bb3bdb0da7 122 SUPERFAMILY SSF54593 12 121 3.36E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS00775 5b9518204c2676f2c7c495bb3bdb0da7 122 Gene3D G3DSA:3.10.180.10 11 122 4.0E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 SMART SM00862 163 239 8.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 SMART SM00448 10 124 1.0E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 SUPERFAMILY SSF52172 10 134 4.84E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 Gene3D G3DSA:3.40.50.2300 4 135 2.7E-33 T 28-03-2018 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 SUPERFAMILY SSF46894 141 240 2.41E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 Pfam PF00072 Response regulator receiver domain 12 125 3.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 6.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06335 be8532075aabffd922bddbf4062a1822 241 Gene3D G3DSA:1.10.10.10 136 241 1.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04140 61bf6d8481a77da23893290dd5017ea0 380 SUPERFAMILY SSF50182 177 242 1.14E-13 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS04140 61bf6d8481a77da23893290dd5017ea0 380 Pfam PF00924 Mechanosensitive ion channel 137 280 2.7E-21 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SmaCSM2_RS04140 61bf6d8481a77da23893290dd5017ea0 380 Gene3D G3DSA:2.30.30.60 194 243 4.5E-8 T 28-03-2018 SmaCSM2_RS08620 e23489f36812a955faf8d9f75c6ae904 473 SUPERFAMILY SSF56954 2 461 1.29E-99 T 28-03-2018 SmaCSM2_RS08620 e23489f36812a955faf8d9f75c6ae904 473 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 459 2.8E-103 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS08620 e23489f36812a955faf8d9f75c6ae904 473 Gene3D G3DSA:1.20.1600.10 19 465 1.8E-85 T 28-03-2018 SmaCSM2_RS08620 e23489f36812a955faf8d9f75c6ae904 473 Pfam PF02321 Outer membrane efflux protein 279 458 5.7E-22 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS08620 e23489f36812a955faf8d9f75c6ae904 473 Pfam PF02321 Outer membrane efflux protein 61 249 5.9E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS15710 461ef7316542be77c3ec03789ad90185 196 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 182 9.7E-30 T 28-03-2018 SmaCSM2_RS15710 461ef7316542be77c3ec03789ad90185 196 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 187 9.4E-31 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SmaCSM2_RS15710 461ef7316542be77c3ec03789ad90185 196 Gene3D G3DSA:3.40.50.1000 1 189 2.4E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS15710 461ef7316542be77c3ec03789ad90185 196 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 185 5.5E-26 T 28-03-2018 SmaCSM2_RS15710 461ef7316542be77c3ec03789ad90185 196 SUPERFAMILY SSF56784 2 186 3.54E-24 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 SUPERFAMILY SSF53850 90 293 1.52E-45 T 28-03-2018 SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 SUPERFAMILY SSF46785 4 108 6.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 Gene3D G3DSA:3.40.190.10 92 175 1.4E-17 T 28-03-2018 SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 Pfam PF03466 LysR substrate binding domain 89 291 3.4E-46 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 Gene3D G3DSA:3.40.190.10 176 264 1.0E-24 T 28-03-2018 SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 Gene3D G3DSA:1.10.10.10 3 84 5.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04915 fd02c474a382f7a61ad52618559684c6 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18575 b8878f8bce81a11ed3d03b3f94cb5bb4 370 Gene3D G3DSA:3.40.50.1100 30 142 1.5E-21 T 28-03-2018 SmaCSM2_RS18575 b8878f8bce81a11ed3d03b3f94cb5bb4 370 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 321 1.0E-42 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS18575 b8878f8bce81a11ed3d03b3f94cb5bb4 370 SUPERFAMILY SSF53686 3 339 2.75E-63 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS18575 b8878f8bce81a11ed3d03b3f94cb5bb4 370 Gene3D G3DSA:3.40.50.1100 143 336 1.1E-34 T 28-03-2018 SmaCSM2_RS11015 acb6e254e4811952566ac5f383617af1 111 Gene3D G3DSA:3.40.30.20 9 111 1.4E-5 T 28-03-2018 SmaCSM2_RS07525 52679e65cb57139b119c00b89fd653c6 210 SMART SM00953 28 175 2.7E-13 T 28-03-2018 IPR014914 RES domain SmaCSM2_RS07525 52679e65cb57139b119c00b89fd653c6 210 Pfam PF08808 RES domain 29 180 7.8E-21 T 28-03-2018 IPR014914 RES domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SUPERFAMILY SSF55785 89 208 2.93E-17 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SMART SM00387 597 689 3.5E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 601 687 6.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SUPERFAMILY SSF55874 564 686 4.06E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 95 212 8.5E-15 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 350 473 3.3E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SUPERFAMILY SSF55785 339 463 3.54E-16 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Pfam PF00989 PAS fold 99 201 1.4E-11 T 28-03-2018 IPR013767 PAS fold GO:0006355 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Pfam PF13426 PAS domain 364 465 1.5E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Gene3D G3DSA:3.30.565.10 555 695 9.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SUPERFAMILY SSF55785 237 351 2.27E-9 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 649 667 9.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 648 9.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 686 9.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SMART SM00091 354 419 4.1E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SMART SM00091 98 165 6.6E-11 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 SMART SM00091 224 291 37.0 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Pfam PF07730 Histidine kinase 494 559 4.6E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Gene3D G3DSA:3.30.450.20 80 221 1.2E-17 T 28-03-2018 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Gene3D G3DSA:3.30.450.20 222 343 1.9E-12 T 28-03-2018 SmaCSM2_RS10335 935a5c8473311c3e4d3674d746c31372 700 Gene3D G3DSA:3.30.450.20 344 494 1.5E-21 T 28-03-2018 SmaCSM2_RS00705 266c300fdc4d263d91218ad8a94049b2 155 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 20 152 1.3E-43 T 28-03-2018 IPR012660 Thioesterase, putative SmaCSM2_RS00705 266c300fdc4d263d91218ad8a94049b2 155 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 16 152 4.6E-42 T 28-03-2018 IPR012660 Thioesterase, putative SmaCSM2_RS00705 266c300fdc4d263d91218ad8a94049b2 155 SUPERFAMILY SSF54637 14 151 3.13E-30 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS00705 266c300fdc4d263d91218ad8a94049b2 155 Gene3D G3DSA:3.10.129.10 2 155 2.0E-20 T 28-03-2018 SmaCSM2_RS01735 bcc28f90f1f0ff42dc38b6b74ef34012 220 Gene3D G3DSA:2.160.10.10 17 107 0.022 T 28-03-2018 SmaCSM2_RS01735 bcc28f90f1f0ff42dc38b6b74ef34012 220 Gene3D G3DSA:2.160.10.10 128 205 0.063 T 28-03-2018 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Gene3D G3DSA:2.40.50.140 1 114 2.5E-45 T 28-03-2018 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.5E-33 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 SMART SM01382 124 253 4.3E-88 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 SUPERFAMILY SSF50249 3 125 1.34E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 SUPERFAMILY SSF50104 127 273 5.66E-57 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Gene3D G3DSA:4.10.950.10 197 274 1.6E-33 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 PIRSF PIRSF002158 6 275 7.4E-97 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 3.5E-54 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Gene3D G3DSA:2.30.30.30 119 195 8.4E-32 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 274 46.473 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 274 1.9E-129 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SmaCSM2_RS04005 6b99b086fe54a3b155503ba4b98627eb 275 SMART SM01383 42 118 2.5E-43 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 SUPERFAMILY SSF53850 94 281 5.25E-21 T 28-03-2018 SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 Gene3D G3DSA:1.10.10.10 1 87 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 SUPERFAMILY SSF46785 1 111 9.59E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 Gene3D G3DSA:3.40.190.10 182 266 2.3E-6 T 28-03-2018 SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.0E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 Pfam PF03466 LysR substrate binding domain 91 265 6.9E-16 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 294 5.7E-113 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP SmaCSM2_RS05725 9b0d10670f44f9674f1c598ea8582cf0 301 Gene3D G3DSA:3.40.190.10 94 181 1.9E-40 T 28-03-2018 SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 SUPERFAMILY SSF75217 71 247 3.86E-48 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 81 1.1E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 Gene3D G3DSA:3.40.1280.10 81 247 1.6E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 5 247 39.351 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 Gene3D G3DSA:3.30.1330.30 1 78 2.2E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 Pfam PF00588 SpoU rRNA Methylase family 100 239 1.1E-40 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 SMART SM00967 7 83 3.5E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 6 246 3.1E-73 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 SmaCSM2_RS06805 63bb15f07c5c493f5e4775adbc41c102 247 SUPERFAMILY SSF55315 2 76 6.83E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 Gene3D G3DSA:3.30.565.10 186 341 1.9E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 228 338 8.8E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 287 9.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 338 9.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 320 9.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 Pfam PF00512 His Kinase A (phospho-acceptor) domain 123 183 4.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 Gene3D G3DSA:1.10.287.130 114 184 2.7E-12 T 28-03-2018 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 SMART SM00387 228 341 3.9E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 SUPERFAMILY SSF55874 192 338 3.54E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 SUPERFAMILY SSF47384 120 182 4.51E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 SMART SM00388 122 189 1.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 SUPERFAMILY SSF55785 10 67 1.93E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS00660 b08d8c023281322abc49b5603937babe 353 Gene3D G3DSA:3.30.450.20 9 105 2.8E-7 T 28-03-2018 SmaCSM2_RS07970 37fe5be836bd51e4e792234bc5dfd9d9 219 Pfam PF06055 Exopolysaccharide synthesis, ExoD 25 201 7.2E-48 T 28-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD SmaCSM2_RS07970 37fe5be836bd51e4e792234bc5dfd9d9 219 PIRSF PIRSF033239 14 216 4.2E-43 T 28-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 Pfam PF03466 LysR substrate binding domain 90 290 9.3E-31 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 SUPERFAMILY SSF53850 92 295 7.42E-35 T 28-03-2018 SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 Gene3D G3DSA:1.10.10.10 2 83 1.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 Gene3D G3DSA:3.40.190.10 176 262 9.5E-17 T 28-03-2018 SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 SUPERFAMILY SSF46785 5 114 3.22E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20205 5f9d2e3697dd65a33cf5cf547a9825c7 301 Gene3D G3DSA:3.40.190.10 90 175 5.8E-13 T 28-03-2018 SmaCSM2_RS15860 50e5876a92de907c222e25e73729757c 332 SUPERFAMILY SSF56281 13 320 2.52E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS15860 50e5876a92de907c222e25e73729757c 332 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 7 329 5.7E-140 T 28-03-2018 IPR026360 Putative exonuclease, DNA ligase-associated SmaCSM2_RS15860 50e5876a92de907c222e25e73729757c 332 Gene3D G3DSA:3.60.15.10 14 327 1.4E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 164 297 4.6E-46 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 312 407 1.3E-19 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 406 1.7E-125 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 SUPERFAMILY SSF69075 309 408 6.8E-23 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 410 29.559 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Gene3D G3DSA:1.10.1200.70 324 408 7.9E-19 T 28-03-2018 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 PIRSF PIRSF000445 1 415 3.0E-148 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 SUPERFAMILY SSF69742 1 150 1.05E-47 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Gene3D G3DSA:3.40.50.720 153 305 6.2E-24 T 28-03-2018 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 148 3.0E-48 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 SUPERFAMILY SSF51735 154 306 6.85E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS03810 9f1bc3b3441f30c22ee586ddd3c767ba 427 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 91 114 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SmaCSM2_RS08535 6bf10274b6311f9855eb7eb2804fcf45 97 Pfam PF07769 psiF repeat 63 95 1.4E-17 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat SmaCSM2_RS08535 6bf10274b6311f9855eb7eb2804fcf45 97 Pfam PF07769 psiF repeat 23 53 1.5E-12 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat SmaCSM2_RS13630 b658ba691a58db4d60e7b3d27d946d90 190 Gene3D G3DSA:3.30.1150.10 10 190 8.6E-21 T 28-03-2018 SmaCSM2_RS13630 b658ba691a58db4d60e7b3d27d946d90 190 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 108 186 1.3E-21 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS13630 b658ba691a58db4d60e7b3d27d946d90 190 SUPERFAMILY SSF74653 106 185 2.35E-20 T 28-03-2018 SmaCSM2_RS13630 b658ba691a58db4d60e7b3d27d946d90 190 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 109 187 7.5E-19 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 Pfam PF00593 TonB dependent receptor 494 941 3.9E-43 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 Gene3D G3DSA:2.170.130.10 51 171 3.9E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 SUPERFAMILY SSF56935 38 230 1.22E-95 T 28-03-2018 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 SUPERFAMILY SSF56935 675 944 1.22E-95 T 28-03-2018 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 SUPERFAMILY SSF56935 486 635 1.22E-95 T 28-03-2018 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 SUPERFAMILY SSF56935 302 437 1.22E-95 T 28-03-2018 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 165 7.3E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18905 e773977f83e1c09a4e673b92617f914f 944 Gene3D G3DSA:2.40.170.20 172 944 5.8E-70 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10960 ea3c41a9e196df07b3c1417e15b96bf5 441 Gene3D G3DSA:1.10.150.130 16 117 3.5E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS10960 ea3c41a9e196df07b3c1417e15b96bf5 441 SUPERFAMILY SSF47823 25 113 1.92E-24 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal SmaCSM2_RS10960 ea3c41a9e196df07b3c1417e15b96bf5 441 SUPERFAMILY SSF56349 149 324 2.53E-36 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS10960 ea3c41a9e196df07b3c1417e15b96bf5 441 Gene3D G3DSA:1.10.443.10 118 318 6.0E-24 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS10960 ea3c41a9e196df07b3c1417e15b96bf5 441 Pfam PF00589 Phage integrase family 154 314 2.7E-11 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 Pfam PF03193 RsgA GTPase 98 271 4.4E-45 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 95 330 3.8E-44 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 40 336 31.184 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 Gene3D G3DSA:1.10.40.50 275 340 4.9E-20 T 28-03-2018 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 Gene3D G3DSA:3.40.50.300 112 271 7.8E-23 T 28-03-2018 SmaCSM2_RS17930 131b60d2431437f038413550282d7c00 369 SUPERFAMILY SSF52540 115 332 1.51E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Gene3D G3DSA:3.30.1360.10 111 230 3.8E-28 T 28-03-2018 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Gene3D G3DSA:3.30.1360.10 4 88 9.4E-18 T 28-03-2018 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 316 34.543 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 SMART SM00662 23 233 2.2E-106 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 SUPERFAMILY SSF47789 250 323 9.03E-26 T 28-03-2018 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 SUPERFAMILY SSF55257 9 53 5.1E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 SUPERFAMILY SSF55257 178 232 5.1E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 SUPERFAMILY SSF56553 53 177 4.19E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 154 9.7E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 307 1.2E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 326 7.0E-35 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 227 1.7E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 Gene3D G3DSA:1.10.150.20 245 327 5.7E-28 T 28-03-2018 SmaCSM2_RS04110 872f094d103af1a6617faae6bb8bb082 332 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 315 1.7E-109 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 SUPERFAMILY SSF51735 161 333 4.76E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 Gene3D G3DSA:3.90.180.10 312 369 2.3E-5 T 28-03-2018 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 2.4E-219 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 Gene3D G3DSA:3.40.50.720 190 311 1.9E-24 T 28-03-2018 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 5.0E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 SMART SM00829 10 367 2.1E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 SUPERFAMILY SSF50129 1 185 2.74E-71 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 Gene3D G3DSA:3.90.180.10 1 189 2.3E-59 T 28-03-2018 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 1.7E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS07470 b1a15a59f309011e1681ed8955a08d2c 369 SUPERFAMILY SSF50129 318 369 1.55E-11 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS07930 b89a85188f2df285e5731221903c23ca 540 Gene3D G3DSA:3.20.20.70 71 499 8.5E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS07930 b89a85188f2df285e5731221903c23ca 540 PIRSF PIRSF500060 5 525 1.0E-221 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria SmaCSM2_RS07930 b89a85188f2df285e5731221903c23ca 540 Pfam PF01645 Conserved region in glutamate synthase 151 468 8.5E-85 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SmaCSM2_RS07930 b89a85188f2df285e5731221903c23ca 540 SUPERFAMILY SSF51395 6 513 2.41E-141 T 28-03-2018 SmaCSM2_RS07930 b89a85188f2df285e5731221903c23ca 540 PIRSF PIRSF006429 4 533 2.4E-160 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 SUPERFAMILY SSF53383 26 209 8.9E-47 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 SUPERFAMILY SSF53383 262 399 8.9E-47 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 Gene3D G3DSA:3.40.640.10 14 214 4.0E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 Gene3D G3DSA:3.90.1150.10 270 401 8.1E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 43 195 1.8E-34 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 PIRSF PIRSF000390 263 401 4.0E-5 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SmaCSM2_RS06235 64bf5e41fb959fd099a8e1197a90c08a 402 PIRSF PIRSF000390 26 203 2.1E-35 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 160 181 - T 28-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 SUPERFAMILY SSF143243 7 66 5.23E-50 T 28-03-2018 SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 SUPERFAMILY SSF143243 111 219 5.23E-50 T 28-03-2018 SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 199 4.7E-37 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 132 187 7.0E-22 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15165 5a5c76a027861e345687a482cf98e481 249 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 7 207 30.875 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 Gene3D G3DSA:3.40.50.720 152 282 8.2E-31 T 28-03-2018 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 Pfam PF16884 N-terminal domain of oxidoreductase 9 112 1.5E-37 T 28-03-2018 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 SMART SM00829 18 338 1.2E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 Pfam PF00107 Zinc-binding dehydrogenase 161 291 3.3E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 SUPERFAMILY SSF50129 7 145 1.28E-36 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 Gene3D G3DSA:3.90.180.10 1 151 2.6E-34 T 28-03-2018 SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 SUPERFAMILY SSF50129 295 339 4.19E-6 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS14835 136f81c57fd00930e11673c49f3cd61c 341 SUPERFAMILY SSF51735 127 305 3.86E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 Pfam PF01218 Coproporphyrinogen III oxidase 6 298 2.4E-127 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 164 188 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 Gene3D G3DSA:3.40.1500.10 1 298 2.1E-132 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 1 274 56.995 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 160 189 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 123 145 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 88 112 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 259 285 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 231 258 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 29 45 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PRINTS PR00073 Coprogen oxidase signature 46 67 1.6E-82 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 PIRSF PIRSF000166 2 298 1.8E-120 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS21200 6ea02cd11d88032ee3cabe2ac6a9f29c 298 SUPERFAMILY SSF102886 4 298 1.57E-129 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 Gene3D G3DSA:1.10.630.10 3 399 4.6E-45 T 28-03-2018 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 Pfam PF00067 Cytochrome P450 229 394 6.4E-36 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 SUPERFAMILY SSF48264 16 389 2.88E-45 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00385 P450 superfamily signature 346 355 4.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00385 P450 superfamily signature 239 252 4.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00385 P450 superfamily signature 355 366 4.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00385 P450 superfamily signature 272 283 4.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00465 E-class P450 group IV signature 316 334 2.0E-12 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00465 E-class P450 group IV signature 339 355 2.0E-12 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00465 E-class P450 group IV signature 355 373 2.0E-12 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08635 95ff0b8f454b0e6d3b3cdd9ab8657115 408 PRINTS PR00465 E-class P450 group IV signature 267 283 2.0E-12 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS17325 a04ac2e5297e4a84eea8a79b3be024b6 896 Pfam PF15976 CS1-pili formation C-terminal 779 870 3.5E-24 T 28-03-2018 IPR031917 Pilus assembly protein, C-terminal domain SmaCSM2_RS17325 a04ac2e5297e4a84eea8a79b3be024b6 896 Pfam PF16967 E-set like domain 281 348 1.5E-24 T 28-03-2018 IPR032636 Pilus assembly protein, E-set like domain SmaCSM2_RS17325 a04ac2e5297e4a84eea8a79b3be024b6 896 Pfam PF17271 TcfC Usher-like barrel domain 354 773 4.8E-134 T 28-03-2018 IPR035224 TcfC, Usher-like barrel domain SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 Gene3D G3DSA:1.10.287.470 112 157 7.2E-11 T 28-03-2018 SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 Gene3D G3DSA:2.40.50.100 159 364 7.5E-10 T 28-03-2018 SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 352 2.7E-67 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 Gene3D G3DSA:2.40.50.100 59 111 3.7E-12 T 28-03-2018 SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 259 1.0E-20 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS17800 d1e4ebce4dda77c92b172b2e57f9e3c8 376 SUPERFAMILY SSF111369 47 259 3.27E-25 T 28-03-2018 SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.1E-123 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 8.4E-131 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 Gene3D G3DSA:3.40.50.1100 21 132 2.0E-36 T 28-03-2018 SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 Gene3D G3DSA:3.40.50.1100 133 307 1.3E-50 T 28-03-2018 SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 292 1.4E-64 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 SUPERFAMILY SSF53686 2 305 3.27E-95 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS17130 8c07ed8e8ee513a29d20c25823b44480 319 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.6E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 614 631 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 SMART SM00878 336 443 6.4E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Pfam PF00364 Biotin-requiring enzyme 594 656 1.9E-14 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Gene3D G3DSA:2.40.50.100 587 659 2.9E-16 T 28-03-2018 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 8.1E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 SUPERFAMILY SSF51230 584 657 2.49E-19 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Gene3D G3DSA:3.30.1490.20 124 209 4.0E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Gene3D G3DSA:3.40.50.20 1 123 2.8E-54 T 28-03-2018 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 SUPERFAMILY SSF52440 1 113 4.39E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Pfam PF02785 Biotin carboxylase C-terminal domain 336 444 1.4E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 Gene3D G3DSA:3.30.470.20 210 446 1.3E-105 T 28-03-2018 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 SUPERFAMILY SSF56059 83 343 4.6E-70 T 28-03-2018 SmaCSM2_RS01035 fd63270cc5952ea555d0957b5e17ed2d 660 SUPERFAMILY SSF51246 331 446 1.62E-38 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 Gene3D G3DSA:3.30.160.20 209 291 6.9E-34 T 28-03-2018 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 SMART SM00937 63 178 1.8E-60 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 Pfam PF00472 RF-1 domain 212 321 2.2E-42 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 358 39.811 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 SUPERFAMILY SSF75620 12 352 4.05E-129 T 28-03-2018 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 358 9.5E-154 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 Pfam PF03462 PCRF domain 13 203 1.1E-68 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SmaCSM2_RS03805 5d5e52197af64514c6c76936927e87f7 360 Gene3D G3DSA:1.20.58.410 4 100 1.7E-13 T 28-03-2018 SmaCSM2_RS20125 02618e44a0ac7f8417e7c3a577f5c42a 122 Pfam PF00816 H-NS histone family 12 115 2.5E-23 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 SmaCSM2_RS20125 02618e44a0ac7f8417e7c3a577f5c42a 122 SMART SM00528 76 121 1.5E-17 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS20125 02618e44a0ac7f8417e7c3a577f5c42a 122 Gene3D G3DSA:4.10.430.10 82 121 1.2E-19 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS20125 02618e44a0ac7f8417e7c3a577f5c42a 122 SUPERFAMILY SSF81273 81 121 1.14E-12 T 28-03-2018 SmaCSM2_RS11555 b9dc6229cfa5c0775fb90396864f96bf 234 Gene3D G3DSA:3.90.70.10 52 209 5.5E-26 T 28-03-2018 SmaCSM2_RS11555 b9dc6229cfa5c0775fb90396864f96bf 234 Pfam PF03412 Peptidase C39 family 53 187 2.8E-17 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SmaCSM2_RS11880 abae8b2d6e685abfe0f30512c893f93f 183 Pfam PF11736 Protein of unknown function (DUF3299) 48 179 3.8E-39 T 28-03-2018 IPR021727 Protein of unknown function DUF3299 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 SUPERFAMILY SSF55347 156 338 1.83E-42 T 28-03-2018 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 202 224 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 Gene3D G3DSA:3.30.360.10 178 334 2.4E-50 T 28-03-2018 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 Gene3D G3DSA:3.40.50.720 14 177 2.1E-21 T 28-03-2018 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 20 143 2.4E-8 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 PIRSF PIRSF036497 13 355 2.0E-76 T 28-03-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 SUPERFAMILY SSF51735 15 178 3.11E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16305 54bed0f31f46af39a4b770d17fa373c9 355 Pfam PF00742 Homoserine dehydrogenase 156 351 3.9E-44 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 5.4E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 SUPERFAMILY SSF52788 1 151 2.88E-45 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 Gene3D G3DSA:3.40.50.2300 1 159 7.7E-45 T 28-03-2018 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 122 137 1.3E-24 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 80 95 1.3E-24 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 1.3E-24 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 1.3E-24 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SmaCSM2_RS07330 17e97287d9723cdb898ea1a3ea0cd71f 162 SMART SM00226 1 150 2.7E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 SUPERFAMILY SSF103473 266 439 3.14E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 SUPERFAMILY SSF103473 475 501 3.14E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 SUPERFAMILY SSF103473 19 213 3.14E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 Gene3D G3DSA:1.20.1250.20 22 219 5.4E-18 T 28-03-2018 SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 Pfam PF07690 Major Facilitator Superfamily 33 429 8.4E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS18005 fdc6062ca3fcfd697332819c46ce606b 509 Gene3D G3DSA:1.20.1250.20 277 507 6.4E-11 T 28-03-2018 SmaCSM2_RS16035 259b893fc996784b0180f4c32988ada2 250 Pfam PF01569 PAP2 superfamily 108 237 4.1E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS16035 259b893fc996784b0180f4c32988ada2 250 SUPERFAMILY SSF48317 23 243 9.81E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS16035 259b893fc996784b0180f4c32988ada2 250 Gene3D G3DSA:1.20.144.10 46 250 8.7E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 Pfam PF08282 haloacid dehalogenase-like hydrolase 13 271 1.8E-61 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 ProSitePatterns PS01229 Hypothetical cof family signature 2. 225 247 - T 28-03-2018 SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 SUPERFAMILY SSF56784 7 276 7.26E-69 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 244 3.8E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 Gene3D G3DSA:3.40.50.1000 2 277 1.2E-42 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS20375 a6bf61d22a469d4a3ee99fdb85fd256b 277 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 12 271 3.1E-61 T 28-03-2018 IPR000150 Cof family GO:0016787 SmaCSM2_RS00525 097aa82a84cc8b8108c138cb1d09e350 544 SUPERFAMILY SSF111283 42 537 3.53E-94 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS00525 097aa82a84cc8b8108c138cb1d09e350 544 Gene3D G3DSA:3.30.2290.10 36 284 7.1E-66 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SmaCSM2_RS00525 097aa82a84cc8b8108c138cb1d09e350 544 Pfam PF01523 Putative modulator of DNA gyrase 59 385 1.2E-57 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS17935 1e2a105ba5845ff8b8337e0dda1ac0bd 424 Pfam PF00155 Aminotransferase class I and II 39 389 1.3E-49 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS17935 1e2a105ba5845ff8b8337e0dda1ac0bd 424 Gene3D G3DSA:3.40.640.10 54 291 1.1E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS17935 1e2a105ba5845ff8b8337e0dda1ac0bd 424 SUPERFAMILY SSF53383 9 405 2.1E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS17935 1e2a105ba5845ff8b8337e0dda1ac0bd 424 Gene3D G3DSA:3.90.1150.10 292 414 2.5E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 SUPERFAMILY SSF55347 132 273 2.78E-27 T 28-03-2018 SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 2.8E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 202 1.4E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 Gene3D G3DSA:3.30.360.10 145 329 2.7E-34 T 28-03-2018 SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 SUPERFAMILY SSF51735 7 157 1.3E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18455 318da26ece21e0177dfab23e06d7a4b1 330 Gene3D G3DSA:3.40.50.720 4 144 2.0E-37 T 28-03-2018 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 Gene3D G3DSA:3.40.190.10 104 193 1.2E-23 T 28-03-2018 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 77 6.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 SUPERFAMILY SSF46785 17 97 1.41E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 Gene3D G3DSA:3.40.190.10 194 279 2.9E-23 T 28-03-2018 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 6.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 6.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 6.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 Gene3D G3DSA:1.10.10.10 17 103 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 Pfam PF03466 LysR substrate binding domain 104 306 1.1E-49 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS00995 44667ee7f2e84116dceca9774b4acb48 322 SUPERFAMILY SSF53850 106 308 7.36E-46 T 28-03-2018 SmaCSM2_RS07760 aa4ff7b184f9bc327d14cd2ad4f76566 146 SUPERFAMILY SSF50249 3 134 8.57E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS07760 aa4ff7b184f9bc327d14cd2ad4f76566 146 Gene3D G3DSA:2.40.50.140 2 118 1.5E-23 T 28-03-2018 SmaCSM2_RS07760 aa4ff7b184f9bc327d14cd2ad4f76566 146 Pfam PF00436 Single-strand binding protein family 9 109 2.3E-12 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SmaCSM2_RS07760 aa4ff7b184f9bc327d14cd2ad4f76566 146 PIRSF PIRSF002070 1 146 7.2E-24 T 28-03-2018 SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 Pfam PF01436 NHL repeat 165 188 8.3E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 SUPERFAMILY SSF101898 228 467 2.62E-25 T 28-03-2018 SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 Gene3D G3DSA:2.120.10.30 323 467 7.1E-13 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 Gene3D G3DSA:2.120.10.30 203 322 1.7E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 Gene3D G3DSA:3.40.30.10 2 152 6.4E-12 T 28-03-2018 SmaCSM2_RS07335 e0c3d71e17b2a2702124e6fb86d21355 470 SUPERFAMILY SSF52833 4 141 2.64E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS18930 975a7803a5ffdf1a8647fbc3b9007fe0 213 Pfam PF02798 Glutathione S-transferase, N-terminal domain 20 81 5.2E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS18930 975a7803a5ffdf1a8647fbc3b9007fe0 213 Gene3D G3DSA:1.20.1050.10 103 213 3.6E-18 T 28-03-2018 SmaCSM2_RS18930 975a7803a5ffdf1a8647fbc3b9007fe0 213 SUPERFAMILY SSF47616 84 204 5.18E-21 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS18930 975a7803a5ffdf1a8647fbc3b9007fe0 213 SUPERFAMILY SSF52833 22 83 1.01E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS18930 975a7803a5ffdf1a8647fbc3b9007fe0 213 Gene3D G3DSA:3.40.30.10 1 102 1.8E-24 T 28-03-2018 SmaCSM2_RS12660 0ea214c4878daf9359c17901f64c6373 306 Pfam PF10994 Protein of unknown function (DUF2817) 83 144 4.1E-7 T 28-03-2018 IPR021259 Protein of unknown function DUF2817 SmaCSM2_RS12660 0ea214c4878daf9359c17901f64c6373 306 Gene3D G3DSA:3.40.630.10 18 305 2.6E-27 T 28-03-2018 SmaCSM2_RS12660 0ea214c4878daf9359c17901f64c6373 306 SUPERFAMILY SSF53187 33 292 3.97E-35 T 28-03-2018 SmaCSM2_RS13960 d4b93f62f162996cb0181fe2ef624532 228 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 6 225 1.0E-78 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 SmaCSM2_RS13960 d4b93f62f162996cb0181fe2ef624532 228 Pfam PF09365 Conserved hypothetical protein (DUF2461) 10 219 5.6E-60 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 SmaCSM2_RS13960 d4b93f62f162996cb0181fe2ef624532 228 PIRSF PIRSF028451 1 228 7.8E-91 T 28-03-2018 IPR015996 Uncharacterised conserved protein UCP028451 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:3.30.70.1430 590 696 3.9E-13 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:1.20.1640.10 296 488 9.9E-31 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82693 43 139 1.24E-18 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82866 824 1048 6.28E-46 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:3.30.70.1430 43 147 4.9E-27 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82693 140 185 2.09E-18 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82693 271 326 2.09E-18 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82714 188 267 7.32E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82866 304 487 1.11E-36 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:3.30.2090.10 739 829 7.7E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:3.30.2090.10 184 270 5.3E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 4.5E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 4.5E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 4.5E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 4.5E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 4.5E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82714 742 828 5.49E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Pfam PF00873 AcrB/AcrD/AcrF family 8 1041 1.3E-163 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 Gene3D G3DSA:1.20.1640.10 831 1046 6.8E-34 T 28-03-2018 SmaCSM2_RS17795 0571745c5acf20fd5536a6b3245f5657 1053 SUPERFAMILY SSF82693 592 684 6.28E-7 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:3.30.450.20 168 290 0.0013 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Pfam PF00072 Response regulator receiver domain 761 869 1.7E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:3.30.450.20 60 167 3.1E-21 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SUPERFAMILY SSF103190 75 191 5.1E-14 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SUPERFAMILY SSF55785 368 467 8.37E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SUPERFAMILY SSF55874 570 731 3.14E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Pfam PF00512 His Kinase A (phospho-acceptor) domain 517 581 1.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SMART SM00388 516 581 1.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:3.40.50.2300 746 880 6.9E-21 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SMART SM00448 759 871 3.5E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Pfam PF12860 PAS fold 369 482 1.2E-40 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SUPERFAMILY SSF52172 757 875 6.12E-22 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SMART SM00387 625 733 9.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:3.30.450.20 321 496 1.2E-17 T 28-03-2018 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:3.30.565.10 576 733 5.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 SUPERFAMILY SSF47384 501 582 1.02E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 689 4.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 711 4.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 675 4.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 717 730 4.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 626 731 9.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS17880 3c3e54c762ac7c7b0d8ce580e48e252e 880 Gene3D G3DSA:1.10.287.130 506 575 3.0E-11 T 28-03-2018 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 SUPERFAMILY SSF46689 9 81 9.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 Gene3D G3DSA:1.10.357.10 62 203 1.4E-20 T 28-03-2018 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 Gene3D G3DSA:1.10.10.60 2 61 7.4E-17 T 28-03-2018 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS01050 8329f6dc214d74d8f84db962954d5c37 205 SUPERFAMILY SSF48498 89 201 5.93E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS19940 0ae2502a34c2ae62da7a7e4c2226cb4b 302 Gene3D G3DSA:2.60.120.330 63 241 9.4E-43 T 28-03-2018 IPR027443 Isopenicillin N synthase-like SmaCSM2_RS19940 0ae2502a34c2ae62da7a7e4c2226cb4b 302 SUPERFAMILY SSF51197 82 224 2.17E-17 T 28-03-2018 SmaCSM2_RS19940 0ae2502a34c2ae62da7a7e4c2226cb4b 302 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 72 225 1.3E-47 T 28-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 SUPERFAMILY SSF90123 28 340 1.23E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 Gene3D G3DSA:1.20.1560.10 21 366 2.5E-25 T 28-03-2018 SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 Gene3D G3DSA:3.40.50.300 374 621 8.8E-68 T 28-03-2018 SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 SUPERFAMILY SSF52540 369 618 3.55E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 SMART SM00382 403 594 1.6E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 ProSitePatterns PS00211 ABC transporters family signature. 520 534 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS14270 453ef7a54ed4463038d6ce4383310c2b 623 Pfam PF00005 ABC transporter 395 548 6.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 Gene3D G3DSA:2.60.120.260 398 636 1.8E-63 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 SUPERFAMILY SSF53474 49 403 5.14E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 SMART SM00939 368 632 4.2E-84 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 382 631 5.0E-36 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 Gene3D G3DSA:3.40.50.1820 36 397 1.3E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 51 635 7.4E-67 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 55 341 9.6E-71 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SmaCSM2_RS12935 811d73013d5ba288949785b15cb9abda 636 SUPERFAMILY SSF49785 411 635 1.42E-70 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 SUPERFAMILY SSF53335 75 267 6.11E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 SMART SM00138 8 271 5.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 Pfam PF01739 CheR methyltransferase, SAM binding domain 75 264 1.2E-35 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 Gene3D G3DSA:3.40.50.150 73 273 1.1E-33 T 28-03-2018 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 PRINTS PR00996 Glutamate methyltransferase family signature 103 123 6.6E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 PRINTS PR00996 Glutamate methyltransferase family signature 228 251 6.6E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 PRINTS PR00996 Glutamate methyltransferase family signature 209 223 6.6E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 PRINTS PR00996 Glutamate methyltransferase family signature 135 151 6.6E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 PRINTS PR00996 Glutamate methyltransferase family signature 67 79 6.6E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 Pfam PF03705 CheR methyltransferase, all-alpha domain 10 61 1.6E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 SUPERFAMILY SSF47757 4 72 9.94E-6 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS09445 dab2a2ff098831a953fe73cf745612a0 274 Gene3D G3DSA:1.10.155.10 2 72 6.5E-5 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS11595 c71f526d6be81b9ae4e1a43630446364 194 Pfam PF11747 Killing trait 11 73 1.8E-18 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS06220 ff94e45f47c270c5dfa62c291abd5214 354 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 139 319 2.9E-11 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition SmaCSM2_RS06220 ff94e45f47c270c5dfa62c291abd5214 354 Gene3D G3DSA:3.40.630.30 156 334 1.9E-19 T 28-03-2018 SmaCSM2_RS06220 ff94e45f47c270c5dfa62c291abd5214 354 SUPERFAMILY SSF55729 162 328 3.0E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS06800 398f7ad5d56751eca2e695f084322615 160 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 29 109 4.8E-19 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 SmaCSM2_RS06800 398f7ad5d56751eca2e695f084322615 160 SUPERFAMILY SSF51316 5 129 3.35E-41 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS06800 398f7ad5d56751eca2e695f084322615 160 Gene3D G3DSA:3.90.1590.10 1 155 5.3E-34 T 28-03-2018 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 SMART SM00344 5 114 1.4E-39 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 Gene3D G3DSA:3.30.70.920 57 151 2.5E-28 T 28-03-2018 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 Gene3D G3DSA:1.10.10.10 5 56 1.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 8.0E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 8.0E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 8.0E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 SUPERFAMILY SSF54909 67 154 4.83E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 3.6E-17 T 28-03-2018 SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 Pfam PF01037 Lrp/AsnC ligand binding domain 71 144 9.1E-21 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SmaCSM2_RS12215 adfd01e7b64828623579d8bd50d1abad 154 SUPERFAMILY SSF46785 3 64 2.65E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 Gene3D G3DSA:1.20.5.340 37 136 8.9E-4 T 28-03-2018 SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 Gene3D G3DSA:2.70.70.10 264 433 6.9E-40 T 28-03-2018 SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 Gene3D G3DSA:1.20.5.50 147 263 0.031 T 28-03-2018 SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 Pfam PF01551 Peptidase family M23 333 426 8.0E-26 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 SUPERFAMILY SSF51261 274 430 3.19E-42 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS01740 0f11406efc8e4a372ee0e1375b6082c2 433 SUPERFAMILY SSF90257 40 128 5.49E-5 T 28-03-2018 SmaCSM2_RS00160 797a8f55ad005171da84176a8ce10cae 406 Pfam PF02321 Outer membrane efflux protein 19 199 2.3E-11 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS00160 797a8f55ad005171da84176a8ce10cae 406 Pfam PF02321 Outer membrane efflux protein 233 393 4.2E-14 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS00160 797a8f55ad005171da84176a8ce10cae 406 SUPERFAMILY SSF56954 4 398 7.46E-52 T 28-03-2018 SmaCSM2_RS00160 797a8f55ad005171da84176a8ce10cae 406 Gene3D G3DSA:1.20.1600.10 11 404 1.2E-45 T 28-03-2018 SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 SMART SM00965 213 261 1.2E-10 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 Pfam PF07660 Secretin and TonB N terminus short domain 214 260 1.9E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 Pfam PF03958 Bacterial type II/III secretion system short domain 288 372 4.8E-15 T 28-03-2018 IPR005644 NolW-like SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 Pfam PF00263 Bacterial type II and III secretion system protein 486 651 3.1E-49 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 596 629 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 PRINTS PR00811 Bacterial general secretion pathway protein D signature 372 382 4.5E-17 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 PRINTS PR00811 Bacterial general secretion pathway protein D signature 482 506 4.5E-17 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 PRINTS PR00811 Bacterial general secretion pathway protein D signature 638 652 4.5E-17 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 PRINTS PR00811 Bacterial general secretion pathway protein D signature 615 633 4.5E-17 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS17270 1ccb616f9ead5138112e12a4fcf9d1e4 656 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 188 650 7.7E-160 T 28-03-2018 IPR013355 Type IV pilus secretin PilQ SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 Pfam PF00672 HAMP domain 186 232 2.7E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 SMART SM00304 183 236 2.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 Gene3D G3DSA:1.10.287.130 227 305 5.0E-7 T 28-03-2018 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 SUPERFAMILY SSF47384 220 303 2.75E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 SUPERFAMILY SSF158472 184 234 5.49E-8 T 28-03-2018 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 452 3.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 Gene3D G3DSA:3.30.565.10 309 455 4.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 SUPERFAMILY SSF55874 294 452 3.41E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 4.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 4.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 4.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS13205 8c32f3f7e46d4cfa50942261d45b206f 459 SMART SM00387 349 458 2.4E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09960 3a7aaa0f4db3f87ae818872b93c13e33 132 Pfam PF01850 PIN domain 3 119 5.0E-9 T 28-03-2018 IPR002716 PIN domain SmaCSM2_RS09960 3a7aaa0f4db3f87ae818872b93c13e33 132 SUPERFAMILY SSF88723 1 129 2.0E-11 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS09960 3a7aaa0f4db3f87ae818872b93c13e33 132 Gene3D G3DSA:3.40.50.1010 1 126 2.8E-11 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS14220 944b7eb3f9a38fb228547bffcf5fa14e 164 Pfam PF05433 Glycine zipper 2TM domain 72 118 9.1E-10 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 SUPERFAMILY SSF55979 246 366 4.83E-34 T 28-03-2018 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Gene3D G3DSA:3.10.150.10 1 122 8.2E-30 T 28-03-2018 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 SMART SM00480 17 362 3.6E-137 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 2.9E-107 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 247 365 8.1E-34 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 PIRSF PIRSF000804 1 366 2.4E-121 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 SUPERFAMILY SSF55979 128 244 5.8E-29 T 28-03-2018 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Gene3D G3DSA:3.10.150.10 123 247 6.4E-34 T 28-03-2018 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 SUPERFAMILY SSF55979 1 116 2.3E-27 T 28-03-2018 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 4.6E-37 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 5.3E-37 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS00010 92faff597fd3613b88f434388593a1fc 366 Gene3D G3DSA:3.10.150.10 248 366 4.6E-27 T 28-03-2018 SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 237 2.6E-50 T 28-03-2018 SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 Gene3D G3DSA:3.40.50.10090 1 37 6.4E-6 T 28-03-2018 SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 Gene3D G3DSA:3.40.50.720 38 242 5.5E-54 T 28-03-2018 SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09375 dfb2c059ceaaac2910371f211d3ea4b1 242 SUPERFAMILY SSF51735 1 241 3.31E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS08340 1f7b3cf5a5e350aa6e0d39629a51d091 161 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 135 1.4E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS08340 1f7b3cf5a5e350aa6e0d39629a51d091 161 Gene3D G3DSA:3.30.70.560 1 155 2.8E-53 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS08340 1f7b3cf5a5e350aa6e0d39629a51d091 161 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 90 101 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS08340 1f7b3cf5a5e350aa6e0d39629a51d091 161 SUPERFAMILY SSF55083 1 145 3.92E-50 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS08340 1f7b3cf5a5e350aa6e0d39629a51d091 161 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 135 1.1E-34 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 Pfam PF00487 Fatty acid desaturase 62 295 1.1E-25 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 PRINTS PR00075 Fatty acid desaturase family 1 signature 218 239 3.7E-20 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 PRINTS PR00075 Fatty acid desaturase family 1 signature 261 275 3.7E-20 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 PRINTS PR00075 Fatty acid desaturase family 1 signature 122 151 3.7E-20 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 PRINTS PR00075 Fatty acid desaturase family 1 signature 85 105 3.7E-20 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SmaCSM2_RS10570 d57dadce6cef3139b77c524ccec19725 316 PRINTS PR00075 Fatty acid desaturase family 1 signature 40 60 3.7E-20 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 SUPERFAMILY SSF48179 164 292 1.36E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 Gene3D G3DSA:3.40.50.720 1 163 1.2E-37 T 28-03-2018 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 292 1.4E-125 T 28-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 SUPERFAMILY SSF51735 1 162 7.88E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 PIRSF PIRSF000103 1 296 1.3E-85 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 292 2.7E-32 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 Gene3D G3DSA:1.10.1040.10 164 296 2.5E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS01200 beb55c41fecf9460aee6bf3958ba20d1 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 5.5E-54 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 Gene3D G3DSA:1.10.10.10 5 87 2.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 Gene3D G3DSA:3.40.190.10 177 263 1.6E-24 T 28-03-2018 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 Pfam PF03466 LysR substrate binding domain 90 293 4.5E-43 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 SUPERFAMILY SSF46785 6 87 8.65E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 SUPERFAMILY SSF53850 92 297 2.9E-46 T 28-03-2018 SmaCSM2_RS18050 de85b5159d3e7369535825988ae7199f 301 Gene3D G3DSA:3.40.190.10 90 176 9.4E-15 T 28-03-2018 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 SUPERFAMILY SSF52540 9 331 1.33E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 PIRSF PIRSF000980 8 1106 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 9 784 2.5E-211 T 28-03-2018 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 SUPERFAMILY SSF52540 344 789 1.7E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 SUPERFAMILY SSF52980 800 1084 1.02E-52 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 8 1106 16.513 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 Gene3D G3DSA:1.10.486.10 423 632 2.2E-55 T 28-03-2018 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 Gene3D G3DSA:1.10.10.160 93 187 3.4E-13 T 28-03-2018 SmaCSM2_RS21625 0a9dd20acfdbcbbd13766fbb364e08ff 1115 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 9 1064 8.4E-303 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 SUPERFAMILY SSF56053 80 173 6.04E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 Gene3D G3DSA:3.90.930.12 5 82 5.0E-17 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 Gene3D G3DSA:3.90.930.12 83 174 9.5E-40 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 173 8.5E-67 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 151 159 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 173 35.182 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 SUPERFAMILY SSF56053 1 79 2.47E-14 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 Pfam PF00347 Ribosomal protein L6 87 161 1.1E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 Pfam PF00347 Ribosomal protein L6 14 79 3.4E-11 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 PRINTS PR00059 Ribosomal protein L6 signature 68 93 3.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 PRINTS PR00059 Ribosomal protein L6 signature 138 159 3.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 PRINTS PR00059 Ribosomal protein L6 signature 96 112 3.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS04065 751ff6853d1c348ef23627436c8fe4f9 174 PIRSF PIRSF002162 3 174 2.3E-40 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 SUPERFAMILY SSF48168 36 252 5.36E-53 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 594 617 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 329 348 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 481 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 528 551 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 566 588 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 PRINTS PR01183 Ribonucleotide reductase large chain signature 655 682 1.8E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 173 250 1.8E-16 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 644 666 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 176 774 2.8E-169 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 Pfam PF02867 Ribonucleotide reductase, barrel domain 254 771 3.6E-143 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 SUPERFAMILY SSF51998 253 776 3.36E-166 T 28-03-2018 SmaCSM2_RS12605 7a87f8bc39519c3d95b2f6466d517214 787 Gene3D G3DSA:3.20.70.20 153 779 6.0E-182 T 28-03-2018 SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 Gene3D G3DSA:3.90.650.10 175 355 9.6E-45 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 Gene3D G3DSA:3.30.1330.10 8 173 3.0E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 SUPERFAMILY SSF55326 18 172 7.92E-39 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 TIGRFAM TIGR00476 selD: selenide, water dikinase 18 327 3.7E-129 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 PIRSF PIRSF036407 12 358 3.5E-111 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 Hamap MF_00625 Selenide, water dikinase [selD]. 16 359 43.033 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 353 2.5E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 SUPERFAMILY SSF56042 175 353 4.19E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS17425 8cbbf98c64f01c7de76f112d47d09ab5 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 167 1.4E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 SUPERFAMILY SSF51338 351 438 2.55E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 8 454 1.5E-201 T 28-03-2018 IPR010252 Formiminoglutamate deiminase SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 SUPERFAMILY SSF51556 55 378 3.6E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 Pfam PF01979 Amidohydrolase family 52 430 5.0E-29 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 Gene3D G3DSA:3.20.20.140 63 382 1.0E-39 T 28-03-2018 SmaCSM2_RS13685 ce88220ae050eb909bd6a21c4fa2fc85 456 Gene3D G3DSA:2.30.40.10 6 62 8.3E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Gene3D G3DSA:1.10.540.10 1 130 4.6E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 128 7.0E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Gene3D G3DSA:1.20.140.10 223 386 7.6E-39 T 28-03-2018 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 381 1.5E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 222 4.2E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 Gene3D G3DSA:2.40.110.10 131 222 6.2E-35 T 28-03-2018 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 SUPERFAMILY SSF47203 234 383 1.55E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 SUPERFAMILY SSF56645 5 233 2.62E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS00840 e95aac372d69c64baa037ff422baa92e 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Gene3D G3DSA:2.160.20.10 998 1290 4.8E-5 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Gene3D G3DSA:2.160.20.10 138 443 7.3E-37 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Gene3D G3DSA:2.160.20.10 1309 1652 0.13 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Gene3D G3DSA:2.160.20.10 754 997 6.0E-8 T 28-03-2018 IPR012334 Pectin lyase fold SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 SUPERFAMILY SSF51126 471 494 1.29E-34 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 SUPERFAMILY SSF51126 146 412 1.29E-34 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3923 4033 8.8E-40 T 28-03-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 SMART SM00912 133 248 1.0E-22 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 169 244 4.7E-20 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS12135 bf23d796bba1b82136bf118a6f74789a 4122 Pfam PF05860 haemagglutination activity domain 152 247 5.6E-18 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 SUPERFAMILY SSF52540 71 351 5.78E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 Pfam PF03880 DbpA RNA binding domain 386 456 5.6E-24 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 SMART SM00490 255 336 2.0E-29 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 SMART SM00487 21 219 9.6E-57 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 SMART SM00382 38 209 0.003 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 Gene3D G3DSA:3.40.50.300 220 455 2.8E-40 T 28-03-2018 SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 Gene3D G3DSA:3.40.50.300 18 219 2.0E-55 T 28-03-2018 SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 Pfam PF00270 DEAD/DEAH box helicase 26 191 2.7E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS08900 71cdfbc68e14b500023ba0c282d93380 458 Pfam PF00271 Helicase conserved C-terminal domain 232 336 5.5E-28 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 SUPERFAMILY SSF48452 192 364 1.58E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 TIGRFAM TIGR03939 PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA 22 673 4.2E-136 T 28-03-2018 IPR023870 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA GO:0022891|GO:0042710 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 Gene3D G3DSA:2.40.160.20 410 457 0.016 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 Gene3D G3DSA:2.40.160.60 458 625 8.0E-4 T 28-03-2018 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 SUPERFAMILY SSF56935 406 542 1.3E-5 T 28-03-2018 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 Gene3D G3DSA:1.25.40.10 6 193 0.0019 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14565 6e39fe46a63cb351aaabd040d7e35c69 675 Gene3D G3DSA:1.25.40.10 194 378 2.6E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12210 9fe99c8b518de3218f17e010210ba963 226 SUPERFAMILY SSF74653 123 193 5.23E-6 T 28-03-2018 SmaCSM2_RS12210 9fe99c8b518de3218f17e010210ba963 226 SMART SM00965 59 110 1.0E-4 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS12210 9fe99c8b518de3218f17e010210ba963 226 Gene3D G3DSA:3.30.1150.10 121 212 2.2E-5 T 28-03-2018 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.0E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.0E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.0E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.0E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.0E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Gene3D G3DSA:3.10.20.30 263 362 3.1E-45 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Pfam PF01926 50S ribosome-binding GTPase 5 128 3.1E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 PIRSF PIRSF006641 1 363 1.4E-155 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.709 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 SUPERFAMILY SSF52540 3 301 8.85E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 8.4E-158 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Gene3D G3DSA:1.10.150.300 110 200 7.7E-27 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 Gene3D G3DSA:3.40.50.300 1 79 2.4E-7 T 28-03-2018 SmaCSM2_RS03850 a6f548c4c216a3ea1d5c806d50c23661 363 SUPERFAMILY SSF81271 279 360 6.1E-36 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SmaCSM2_RS05960 85c0d8987298c6d472e5d2d92d5bdd20 322 Pfam PF04773 FecR protein 118 206 3.1E-14 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS05960 85c0d8987298c6d472e5d2d92d5bdd20 322 Pfam PF16344 Domain of unknown function (DUF4974) 216 301 1.9E-7 T 28-03-2018 IPR032508 Protein FecR, C-terminal SmaCSM2_RS05960 85c0d8987298c6d472e5d2d92d5bdd20 322 Gene3D G3DSA:2.60.120.10 52 198 0.054 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS05960 85c0d8987298c6d472e5d2d92d5bdd20 322 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 2.6E-12 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS05960 85c0d8987298c6d472e5d2d92d5bdd20 322 PIRSF PIRSF018266 3 318 3.7E-63 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 Gene3D G3DSA:3.10.310.10 2 129 9.1E-27 T 28-03-2018 SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 SUPERFAMILY SSF54506 4 290 1.19E-61 T 28-03-2018 SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 Pfam PF02567 Phenazine biosynthesis-like protein 9 272 1.1E-49 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 PIRSF PIRSF016184 1 292 3.7E-69 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 Gene3D G3DSA:3.10.310.10 130 281 2.9E-28 T 28-03-2018 SmaCSM2_RS05365 a72f828b57685c48f9409d99546a6e31 292 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 275 8.7E-49 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 SUPERFAMILY SSF56935 34 811 4.4E-108 T 28-03-2018 SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 Pfam PF00593 TonB dependent receptor 287 806 3.1E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 171 4.9E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 Gene3D G3DSA:2.170.130.10 24 170 2.2E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16845 77e7d29f6b5c24075dea8902f1cdce73 811 Gene3D G3DSA:2.40.170.20 171 811 5.3E-69 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18100 e2f535ad6eacda5065083c251edcdd06 323 SUPERFAMILY SSF56281 32 319 1.06E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS18100 e2f535ad6eacda5065083c251edcdd06 323 SMART SM00849 91 297 6.2E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS18100 e2f535ad6eacda5065083c251edcdd06 323 Gene3D G3DSA:3.60.15.10 28 323 8.4E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS18100 e2f535ad6eacda5065083c251edcdd06 323 Pfam PF00753 Metallo-beta-lactamase superfamily 91 295 1.8E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 Pfam PF00813 FliP family 60 252 8.9E-73 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 60 256 1.5E-76 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 97 116 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 206 227 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 230 255 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 185 205 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 58 77 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 77 97 6.6E-61 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 233 245 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 185 200 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 128 142 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 116 128 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 56 65 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 178 190 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 156 168 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS10130 585d6c074252ec88add15fc857efbfc4 259 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 246 256 5.9E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 SmaCSM2_RS19635 98d0b3c1bba7cf86a3b6959020be5f21 206 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS19635 98d0b3c1bba7cf86a3b6959020be5f21 206 SUPERFAMILY SSF55811 6 151 5.01E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS19635 98d0b3c1bba7cf86a3b6959020be5f21 206 Gene3D G3DSA:3.90.79.10 1 163 2.5E-31 T 28-03-2018 SmaCSM2_RS19635 98d0b3c1bba7cf86a3b6959020be5f21 206 Pfam PF00293 NUDIX domain 7 129 9.6E-25 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS19635 98d0b3c1bba7cf86a3b6959020be5f21 206 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 36.764 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH SmaCSM2_RS19005 d06cb3313ae3ffb747948637d950cdae 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 11 286 5.1E-37 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SmaCSM2_RS19005 d06cb3313ae3ffb747948637d950cdae 306 PIRSF PIRSF026649 1 297 5.0E-72 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SmaCSM2_RS18290 3bc2634a7c35ebdd9d360a74056c3af0 127 SMART SM00749 59 122 9.4E-8 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria SmaCSM2_RS18290 3bc2634a7c35ebdd9d360a74056c3af0 127 Pfam PF04972 BON domain 54 121 6.3E-18 T 28-03-2018 IPR007055 BON domain SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 Gene3D G3DSA:3.40.50.200 113 507 7.7E-81 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 188 199 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 SUPERFAMILY SSF52743 248 504 9.03E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 SUPERFAMILY SSF52743 169 219 9.03E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 202 1.7E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 PRINTS PR00723 Subtilisin serine protease family (S8) signature 436 452 1.7E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 264 1.7E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 Gene3D G3DSA:2.60.120.380 511 612 2.3E-11 T 28-03-2018 SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 537 602 1.3E-11 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 437 447 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SmaCSM2_RS02955 f3acfb400988e93dc8c72a6bd24533b3 617 Pfam PF00082 Subtilase family 183 480 8.1E-49 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS17145 3969da8d5bd1afc244a92b8890233e7b 334 Pfam PF00274 Fructose-bisphosphate aldolase class-I 6 333 5.0E-139 T 28-03-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17145 3969da8d5bd1afc244a92b8890233e7b 334 Gene3D G3DSA:3.20.20.70 2 334 3.0E-153 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS17145 3969da8d5bd1afc244a92b8890233e7b 334 ProSitePatterns PS00158 Fructose-bisphosphate aldolase class-I active site. 211 221 - T 28-03-2018 IPR029768 Fructose-bisphosphate aldolase class-I active site KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17145 3969da8d5bd1afc244a92b8890233e7b 334 SUPERFAMILY SSF51569 4 333 3.56E-133 T 28-03-2018 SmaCSM2_RS00200 135c9212d9f2af670e71dcaa59ac1706 696 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 156 9.7E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00200 135c9212d9f2af670e71dcaa59ac1706 696 Gene3D G3DSA:2.40.170.20 170 694 5.3E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00200 135c9212d9f2af670e71dcaa59ac1706 696 Gene3D G3DSA:2.170.130.10 22 161 1.3E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00200 135c9212d9f2af670e71dcaa59ac1706 696 Pfam PF00593 TonB dependent receptor 272 694 6.1E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00200 135c9212d9f2af670e71dcaa59ac1706 696 SUPERFAMILY SSF56935 23 695 6.41E-96 T 28-03-2018 SmaCSM2_RS13370 65e642853e1c0261adf3bd62f83d1960 335 Gene3D G3DSA:3.30.20.10 80 136 7.4E-15 T 28-03-2018 SmaCSM2_RS13370 65e642853e1c0261adf3bd62f83d1960 335 Pfam PF00182 Chitinase class I 100 151 7.4E-7 T 28-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS13370 65e642853e1c0261adf3bd62f83d1960 335 SUPERFAMILY SSF53955 13 191 1.38E-35 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS12800 00af369f336996bce28593f058ba25d3 141 Pfam PF07681 DoxX 10 96 2.3E-12 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 SMART SM00861 321 485 9.3E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 SUPERFAMILY SSF52518 297 480 1.28E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 ProSitePatterns PS00802 Transketolase signature 2. 427 443 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Gene3D G3DSA:3.40.50.920 497 621 6.4E-30 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Pfam PF02779 Transketolase, pyrimidine binding domain 320 480 2.0E-36 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 SUPERFAMILY SSF52518 7 351 1.63E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Gene3D G3DSA:3.40.50.970 1 299 9.4E-77 T 28-03-2018 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 SUPERFAMILY SSF52922 493 619 7.33E-28 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 11 619 5.8E-258 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Gene3D G3DSA:3.40.50.970 300 490 8.7E-60 T 28-03-2018 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 284 6.4E-115 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Pfam PF02780 Transketolase, C-terminal domain 497 613 9.2E-23 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SmaCSM2_RS14870 0828f7ad6f5aeffdfe56be8da81dc3a3 635 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 622 44.906 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS12960 b240572dc8c4dae6a8caa96d974c57c5 144 Gene3D G3DSA:3.10.180.10 30 144 7.0E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS12960 b240572dc8c4dae6a8caa96d974c57c5 144 SUPERFAMILY SSF54593 28 140 5.21E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 SUPERFAMILY SSF63867 330 405 7.85E-14 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Gene3D G3DSA:3.90.105.10 20 55 2.4E-10 T 28-03-2018 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Pfam PF00994 Probable molybdopterin binding domain 180 320 2.8E-26 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 SUPERFAMILY SSF63882 1 176 4.58E-44 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 SMART SM00852 180 321 1.5E-35 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 317 7.2E-27 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Gene3D G3DSA:2.40.340.10 331 402 2.1E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 255 289 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Gene3D G3DSA:2.170.190.11 56 141 4.8E-22 T 28-03-2018 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Pfam PF03454 MoeA C-terminal region (domain IV) 333 402 7.4E-11 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 SUPERFAMILY SSF53218 177 325 1.44E-36 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Gene3D G3DSA:3.40.980.10 150 330 1.4E-47 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12325 05a0e388d0d715bb2a593427601bcd51 417 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 167 2.0E-38 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 Gene3D G3DSA:3.40.190.10 196 298 1.3E-6 T 28-03-2018 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 Gene3D G3DSA:3.40.190.10 89 195 7.5E-19 T 28-03-2018 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 Pfam PF03466 LysR substrate binding domain 88 296 2.0E-36 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 SUPERFAMILY SSF46785 2 111 4.79E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 Gene3D G3DSA:1.10.10.10 2 88 2.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12950 7fdaaee90a3d3ef5dbe70a849b775d75 298 SUPERFAMILY SSF53850 89 297 3.72E-35 T 28-03-2018 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 328 1.5E-36 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 SUPERFAMILY SSF55021 336 412 2.04E-17 T 28-03-2018 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 202 224 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Pfam PF01842 ACT domain 348 404 1.6E-8 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 SUPERFAMILY SSF52283 10 137 8.29E-47 T 28-03-2018 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Gene3D G3DSA:3.30.70.260 330 412 1.1E-16 T 28-03-2018 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 SUPERFAMILY SSF51735 110 297 1.23E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Gene3D G3DSA:3.40.50.720 1 138 4.7E-45 T 28-03-2018 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 296 1.0E-52 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 156 183 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SmaCSM2_RS09705 69f7a9b2083e44a8398b049cbe65121e 413 Gene3D G3DSA:3.40.50.720 139 297 1.1E-43 T 28-03-2018 SmaCSM2_RS07610 a61cf81cbc15fd172b6445ef41e37420 127 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 17 110 1.5E-34 T 28-03-2018 IPR019110 Uncharacterised protein family, RAQPRD SmaCSM2_RS07610 a61cf81cbc15fd172b6445ef41e37420 127 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 35 109 1.4E-26 T 28-03-2018 IPR019110 Uncharacterised protein family, RAQPRD SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 SMART SM00448 11 121 3.1E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 SUPERFAMILY SSF46894 136 236 1.05E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 Gene3D G3DSA:1.10.10.10 131 238 1.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 236 5.4E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 SMART SM00862 159 236 2.3E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 SUPERFAMILY SSF52172 8 130 1.71E-38 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 Gene3D G3DSA:3.40.50.2300 1 130 3.2E-35 T 28-03-2018 SmaCSM2_RS11695 6aed4948b4c5c3a2b15ff92b0af6c80a 238 Pfam PF00072 Response regulator receiver domain 13 122 2.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 TIGRFAM TIGR00417 speE: spermidine synthase 7 277 3.5E-78 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 Gene3D G3DSA:2.30.140.10 1 56 4.9E-15 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 Pfam PF17284 Spermidine synthase tetramerisation domain 7 58 9.9E-11 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 283 35.226 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 SUPERFAMILY SSF53335 7 282 4.64E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 Pfam PF01564 Spermine/spermidine synthase domain 63 242 5.0E-52 T 28-03-2018 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 Gene3D G3DSA:3.40.50.150 60 284 8.3E-37 T 28-03-2018 SmaCSM2_RS19935 a415fd108729b3b129891f975b7f3d1b 284 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 83 96 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 Pfam PF00107 Zinc-binding dehydrogenase 164 282 5.1E-9 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 SMART SM00829 21 328 2.5E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 SUPERFAMILY SSF51735 121 297 4.03E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 9 330 5.3E-119 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 Gene3D G3DSA:3.40.50.720 170 275 4.3E-11 T 28-03-2018 SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 Gene3D G3DSA:3.90.180.10 8 169 1.3E-30 T 28-03-2018 SmaCSM2_RS16140 8e780e55302bf13682a761aae63a83b5 331 SUPERFAMILY SSF50129 8 149 3.96E-38 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 Pfam PF00255 Glutathione peroxidase 7 111 3.1E-36 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 SUPERFAMILY SSF52833 4 179 5.23E-57 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 Gene3D G3DSA:3.40.30.10 3 181 1.3E-42 T 28-03-2018 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 PIRSF PIRSF000303 1 181 5.7E-59 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 PRINTS PR01011 Glutathione peroxidase family signature 141 150 3.8E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 PRINTS PR01011 Glutathione peroxidase family signature 23 40 3.8E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS21660 49f10fec5dffe9dbeee8d3668937dcd1 181 PRINTS PR01011 Glutathione peroxidase family signature 58 74 3.8E-18 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:3.30.2090.10 214 300 8.8E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82866 843 1064 2.88E-46 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82693 181 214 5.23E-13 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82693 300 356 5.23E-13 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82714 216 297 1.24E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82714 758 843 2.75E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:1.20.1640.10 845 1064 4.1E-31 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82693 42 128 3.14E-22 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Pfam PF00873 AcrB/AcrD/AcrF family 5 1058 6.9E-272 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:1.20.1640.10 319 543 7.1E-31 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1060 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:3.30.70.1430 601 752 1.1E-10 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:3.30.70.1430 42 143 1.0E-24 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 Gene3D G3DSA:3.30.2090.10 757 844 5.4E-24 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82866 323 530 3.92E-29 T 28-03-2018 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 503 526 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 362 385 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 478 501 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 PRINTS PR00702 Acriflavin resistance protein family signature 586 603 1.5E-16 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21310 0ea225409c09158864b2b3c55fe54e97 1069 SUPERFAMILY SSF82693 600 690 4.71E-5 T 28-03-2018 SmaCSM2_RS01485 f04c160c9b5e217977250ee19a1d1aed 178 SUPERFAMILY SSF81342 7 177 4.71E-33 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SmaCSM2_RS01485 f04c160c9b5e217977250ee19a1d1aed 178 Pfam PF01292 Prokaryotic cytochrome b561 8 176 5.8E-26 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 SmaCSM2_RS01485 f04c160c9b5e217977250ee19a1d1aed 178 Gene3D G3DSA:1.20.950.20 5 178 4.3E-31 T 28-03-2018 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 426 9.6E-196 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 Gene3D G3DSA:3.40.640.10 6 292 7.0E-62 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 425 1.2E-139 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 Gene3D G3DSA:3.90.1150.10 294 428 9.1E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 PIRSF PIRSF001434 1 428 1.7E-131 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SmaCSM2_RS16790 436bcce21ce7b6b4c156be0fea03da72 428 SUPERFAMILY SSF53383 7 426 6.78E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS10650 24332cd11c01c289624df6f7866229a6 351 Pfam PF02486 Replication initiation factor 151 317 4.5E-25 T 28-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 SmaCSM2_RS08215 bf7cad06eb5fe5a2a8e4e7298b84327f 308 SUPERFAMILY SSF46626 82 176 1.32E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08215 bf7cad06eb5fe5a2a8e4e7298b84327f 308 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 197 281 3.0E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08215 bf7cad06eb5fe5a2a8e4e7298b84327f 308 Gene3D G3DSA:1.10.760.10 172 285 2.5E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08215 bf7cad06eb5fe5a2a8e4e7298b84327f 308 Gene3D G3DSA:1.10.760.10 73 171 6.9E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08215 bf7cad06eb5fe5a2a8e4e7298b84327f 308 SUPERFAMILY SSF46626 182 292 4.88E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 15 256 8.0E-49 T 28-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Gene3D G3DSA:1.25.40.10 132 181 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Pfam PF13432 Tetratricopeptide repeat 167 222 9.4E-4 T 28-03-2018 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Pfam PF13432 Tetratricopeptide repeat 57 119 5.2E-6 T 28-03-2018 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Gene3D G3DSA:1.25.40.10 112 131 4.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Gene3D G3DSA:1.25.40.10 48 111 3.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 Gene3D G3DSA:1.25.40.10 182 260 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SMART SM00028 157 190 4.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SMART SM00028 53 86 410.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SMART SM00028 87 120 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SMART SM00028 191 224 57.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SMART SM00028 121 154 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS09050 adfc32f2458031d48701946f987417ff 261 SUPERFAMILY SSF48452 64 225 3.86E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15200 c2f3c1f13ce4227cf6a0f0b6aa60ebdd 625 PIRSF PIRSF004950 13 625 1.0E-150 T 28-03-2018 IPR012159 Inner membrane protein YejM SmaCSM2_RS15200 c2f3c1f13ce4227cf6a0f0b6aa60ebdd 625 SUPERFAMILY SSF53649 260 604 1.67E-57 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS15200 c2f3c1f13ce4227cf6a0f0b6aa60ebdd 625 Pfam PF00884 Sulfatase 261 541 3.0E-31 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SmaCSM2_RS15200 c2f3c1f13ce4227cf6a0f0b6aa60ebdd 625 Pfam PF11893 Domain of unknown function (DUF3413) 19 255 1.3E-36 T 28-03-2018 IPR024588 Inner membrane protein YejM, N-terminal SmaCSM2_RS15200 c2f3c1f13ce4227cf6a0f0b6aa60ebdd 625 Gene3D G3DSA:3.40.720.10 260 580 2.8E-39 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Pfam PF00501 AMP-binding enzyme 40 444 8.4E-77 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Gene3D G3DSA:3.40.50.980 180 365 2.4E-33 T 28-03-2018 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Gene3D G3DSA:3.40.50.980 30 179 2.2E-30 T 28-03-2018 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Gene3D G3DSA:3.30.300.30 439 544 1.1E-24 T 28-03-2018 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Gene3D G3DSA:2.30.38.10 366 438 2.9E-20 T 28-03-2018 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 SUPERFAMILY SSF56801 12 539 9.16E-134 T 28-03-2018 SmaCSM2_RS12505 34a7f8a46097a4326645c1176a74dd65 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 528 3.4E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 SMART SM00014 120 234 8.7E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PRINTS PR00483 Bacterial acid phosphatase class A signature 75 94 2.2E-38 T 28-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PRINTS PR00483 Bacterial acid phosphatase class A signature 231 249 2.2E-38 T 28-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PRINTS PR00483 Bacterial acid phosphatase class A signature 139 157 2.2E-38 T 28-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PRINTS PR00483 Bacterial acid phosphatase class A signature 165 191 2.2E-38 T 28-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PRINTS PR00483 Bacterial acid phosphatase class A signature 197 221 2.2E-38 T 28-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 Gene3D G3DSA:1.20.144.10 26 256 1.5E-39 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 ProSitePatterns PS01157 Class A bacterial acid phosphatases signature. 169 176 - T 28-03-2018 IPR018296 Acid phosphatase, class A, bacterial, conserved site GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 SUPERFAMILY SSF48317 37 251 1.13E-44 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 PIRSF PIRSF000897 8 270 1.2E-99 T 28-03-2018 IPR011158 Nonspecific acid phosphatase, class A GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 SmaCSM2_RS00275 5f9cc1b28581813a71de92d528e700b2 279 Pfam PF01569 PAP2 superfamily 132 233 8.3E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS06095 559b9ac042b433fb5f928f2b0ae1a21b 135 Pfam PF08818 Domain of unknown function (DU1801) 32 125 1.1E-18 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 SmaCSM2_RS06095 559b9ac042b433fb5f928f2b0ae1a21b 135 SUPERFAMILY SSF159888 19 129 1.57E-17 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82693 40 135 7.85E-19 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82693 145 181 2.25E-10 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82693 264 306 2.25E-10 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82714 693 776 1.44E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 2.4E-35 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Gene3D G3DSA:1.20.1640.10 780 1002 2.2E-43 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Gene3D G3DSA:1.20.1640.10 265 490 1.5E-35 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82866 295 487 7.85E-31 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Gene3D G3DSA:3.30.70.1430 40 143 7.1E-21 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82866 775 1003 8.5E-46 T 28-03-2018 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Pfam PF00873 AcrB/AcrD/AcrF family 4 1000 1.2E-203 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Gene3D G3DSA:3.30.2090.10 181 264 1.8E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 Gene3D G3DSA:3.30.2090.10 690 779 2.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS08950 03cdd4f2ab35f389a0a7c12cc1d488d1 1027 SUPERFAMILY SSF82714 183 260 8.89E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS13145 bfe2a28a17aac01fc3ccf1e6bc074101 126 SUPERFAMILY SSF52172 5 122 1.41E-18 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS13145 bfe2a28a17aac01fc3ccf1e6bc074101 126 Pfam PF00072 Response regulator receiver domain 9 62 5.7E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13145 bfe2a28a17aac01fc3ccf1e6bc074101 126 SMART SM00448 7 115 2.7E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13145 bfe2a28a17aac01fc3ccf1e6bc074101 126 Gene3D G3DSA:3.40.50.2300 2 126 5.6E-15 T 28-03-2018 SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 Gene3D G3DSA:3.30.750.80 73 178 2.2E-24 T 28-03-2018 SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 Gene3D G3DSA:2.30.130.10 9 70 3.7E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 Gene3D G3DSA:3.40.50.150 179 389 9.9E-40 T 28-03-2018 SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 SUPERFAMILY SSF53335 78 384 4.44E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 174 311 9.0E-19 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 SmaCSM2_RS21720 b288a88068e80faae451b3867125fb48 389 SUPERFAMILY SSF88697 12 69 1.22E-10 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Pfam PF10396 GTP-binding protein TrmE N-terminus 9 122 2.1E-36 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Pfam PF01926 50S ribosome-binding GTPase 221 315 1.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Pfam PF12631 MnmE helical domain 125 446 1.6E-50 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Gene3D G3DSA:1.20.120.430 124 281 2.5E-21 T 28-03-2018 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 SUPERFAMILY SSF52540 75 151 2.76E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 SUPERFAMILY SSF52540 187 365 2.76E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Gene3D G3DSA:1.20.120.430 282 449 2.7E-29 T 28-03-2018 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 285 7.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 241 7.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Gene3D G3DSA:3.30.1360.120 2 123 4.4E-42 T 28-03-2018 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 14 449 1.6E-93 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 222 317 3.9E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 SUPERFAMILY SSF116878 375 449 3.92E-43 T 28-03-2018 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 SUPERFAMILY SSF116878 123 222 3.92E-43 T 28-03-2018 SmaCSM2_RS21750 be7804751f5d29ef9cfefd27fad1a1d9 449 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 449 31.416 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 SmaCSM2_RS10680 80f5472b7c2f75a5ddbbfab9fc1998da 400 SUPERFAMILY SSF52540 5 160 1.59E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10680 80f5472b7c2f75a5ddbbfab9fc1998da 400 Pfam PF05707 Zonular occludens toxin (Zot) 3 184 8.0E-20 T 28-03-2018 IPR008900 Zona occludens toxin SmaCSM2_RS10680 80f5472b7c2f75a5ddbbfab9fc1998da 400 Gene3D G3DSA:3.40.50.300 1 185 6.9E-12 T 28-03-2018 SmaCSM2_RS05755 899b27fc8e765bbdf624c066ce8722fa 414 Pfam PF05684 Protein of unknown function (DUF819) 15 409 9.9E-136 T 28-03-2018 IPR008537 Protein of unknown function DUF819 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 SUPERFAMILY SSF52540 18 341 4.28E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 6 833 0.0 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 Pfam PF04408 Helicase associated domain (HA2) 386 483 5.9E-21 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 SMART SM00490 228 330 1.8E-17 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 SMART SM00847 385 514 8.0E-13 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 SMART SM00487 7 190 8.9E-14 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 Gene3D G3DSA:3.40.50.300 182 349 2.0E-45 T 28-03-2018 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 Pfam PF08482 ATP-dependent helicase C-terminal 682 820 8.6E-51 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 Gene3D G3DSA:3.40.50.300 6 165 1.2E-20 T 28-03-2018 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 PIRSF PIRSF005496 1 834 0.0 T 28-03-2018 SmaCSM2_RS20950 5562755c513fe80e7f388b440d630deb 834 Pfam PF00271 Helicase conserved C-terminal domain 210 329 9.2E-16 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS02400 c45c675fd9f44ec2667ff9b7207a715a 284 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 281 4.0E-119 T 28-03-2018 IPR022522 Flagellar motor stator, MotA SmaCSM2_RS02400 c45c675fd9f44ec2667ff9b7207a715a 284 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 235 5.2E-8 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS02400 c45c675fd9f44ec2667ff9b7207a715a 284 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PIRSF PIRSF001369 11 385 1.5E-109 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 Gene3D G3DSA:1.10.580.10 24 364 2.4E-79 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 17 384 9.6E-153 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 SUPERFAMILY SSF48256 18 378 6.28E-122 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 Pfam PF00285 Citrate synthase, C-terminal domain 18 366 3.0E-113 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PRINTS PR00143 Citrate synthase signature 185 200 1.8E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PRINTS PR00143 Citrate synthase signature 260 280 1.8E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PRINTS PR00143 Citrate synthase signature 207 235 1.8E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PRINTS PR00143 Citrate synthase signature 317 333 1.8E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS16200 c198e3359ca92e5aed6a6b7b96a2f705 385 PRINTS PR00143 Citrate synthase signature 337 351 1.8E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SmaCSM2_RS20150 5a9bc1fae07c17c231f8e9414d40c0a6 246 Pfam PF03358 NADPH-dependent FMN reductase 30 175 2.4E-29 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS20150 5a9bc1fae07c17c231f8e9414d40c0a6 246 SUPERFAMILY SSF52218 17 222 3.1E-62 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS20150 5a9bc1fae07c17c231f8e9414d40c0a6 246 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 4 221 1.2E-116 T 28-03-2018 IPR014063 Arsenate resistance ArsH SmaCSM2_RS20150 5a9bc1fae07c17c231f8e9414d40c0a6 246 Gene3D G3DSA:3.40.50.360 17 221 6.7E-48 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS17905 d2515e94928cff6b22a5343030e7f0d1 379 Gene3D G3DSA:2.40.160.10 1 379 4.0E-42 T 28-03-2018 SmaCSM2_RS17905 d2515e94928cff6b22a5343030e7f0d1 379 Pfam PF07396 Phosphate-selective porin O and P 24 379 1.1E-80 T 28-03-2018 IPR010870 Phosphate-selective porin O/P SmaCSM2_RS17905 d2515e94928cff6b22a5343030e7f0d1 379 SUPERFAMILY SSF56935 20 373 2.71E-12 T 28-03-2018 SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 SMART SM00382 53 231 3.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 Gene3D G3DSA:3.40.50.300 4 282 5.0E-43 T 28-03-2018 SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 Gene3D G3DSA:2.70.50.60 283 423 4.4E-28 T 28-03-2018 SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 Pfam PF00005 ABC transporter 44 176 4.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 SUPERFAMILY SSF52540 32 224 1.81E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02705 bf5abb5e709b0089f38301a3641d26d0 438 Pfam PF14524 Wzt C-terminal domain 287 422 3.9E-26 T 28-03-2018 IPR029439 Wzt, C-terminal SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Pfam PF11638 DnaA N-terminal domain 1 62 7.7E-13 T 28-03-2018 IPR024633 DnaA N-terminal domain SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 354 420 1.3E-29 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 SUPERFAMILY SSF48295 340 442 9.94E-36 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 SMART SM00760 351 420 1.5E-39 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 1 442 32.018 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 266 1.3E-46 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 401 420 1.3E-46 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 1.3E-46 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 141 161 1.3E-46 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 187 1.3E-46 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Gene3D G3DSA:3.40.50.300 104 272 3.6E-18 T 28-03-2018 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Gene3D G3DSA:1.10.1750.10 345 442 2.3E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 SUPERFAMILY SSF52540 108 319 1.47E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 4 441 6.0E-164 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 SMART SM00382 140 271 2.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 ProSitePatterns PS01008 DnaA protein signature. 401 420 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Pfam PF00308 Bacterial dnaA protein 107 325 2.0E-85 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA SmaCSM2_RS00005 276bf8a56f6d30008ffc11b4340ef62b 443 Gene3D G3DSA:1.10.8.60 274 344 8.2E-26 T 28-03-2018 SmaCSM2_RS03015 2bd0e3b5fc35ca48965e8b9a871ec655 283 Pfam PF00535 Glycosyl transferase family 2 14 131 5.6E-9 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS03015 2bd0e3b5fc35ca48965e8b9a871ec655 283 Gene3D G3DSA:3.90.550.10 4 266 8.7E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS03015 2bd0e3b5fc35ca48965e8b9a871ec655 283 SUPERFAMILY SSF53448 12 219 4.97E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 Pfam PF00990 Diguanylate cyclase, GGDEF domain 329 489 7.8E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 SUPERFAMILY SSF109604 12 271 1.73E-57 T 28-03-2018 SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 Gene3D G3DSA:3.30.70.270 337 497 2.9E-51 T 28-03-2018 SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 SUPERFAMILY SSF55073 334 492 3.92E-45 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 325 492 1.2E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 SMART SM00267 318 493 4.5E-53 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 Gene3D G3DSA:1.10.3210.10 2 336 8.5E-33 T 28-03-2018 SmaCSM2_RS06640 764d1fda92e200137c8092a0b035c0e3 512 Pfam PF08668 HDOD domain 15 208 6.9E-51 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD SmaCSM2_RS02495 984967b077e8cace293240393db51101 212 SUPERFAMILY SSF51735 1 208 1.35E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02495 984967b077e8cace293240393db51101 212 Gene3D G3DSA:3.40.50.720 1 212 6.9E-27 T 28-03-2018 SmaCSM2_RS02495 984967b077e8cace293240393db51101 212 Pfam PF13460 NAD(P)H-binding 7 194 4.0E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS07995 d9a1ef4430053095baa554bbe1458cac 192 SUPERFAMILY SSF55729 11 181 7.15E-47 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS07995 d9a1ef4430053095baa554bbe1458cac 192 Gene3D G3DSA:3.40.630.30 6 189 6.2E-35 T 28-03-2018 SmaCSM2_RS07995 d9a1ef4430053095baa554bbe1458cac 192 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 4.4E-32 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS04185 2a21e0a83a214a7af8eac3ed060ce981 351 PIRSF PIRSF038192 1 351 3.1E-111 T 28-03-2018 IPR017429 Suppressor of fused, bacterial SmaCSM2_RS04185 2a21e0a83a214a7af8eac3ed060ce981 351 Pfam PF05076 Suppressor of fused protein (SUFU) 42 208 1.1E-47 T 28-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 SmaCSM2_RS04185 2a21e0a83a214a7af8eac3ed060ce981 351 SUPERFAMILY SSF103359 8 228 9.94E-74 T 28-03-2018 SmaCSM2_RS03110 b203e3146dd244f46af7287074fe8113 173 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.1E-60 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SmaCSM2_RS03110 b203e3146dd244f46af7287074fe8113 173 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 84.205 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SmaCSM2_RS03110 b203e3146dd244f46af7287074fe8113 173 Pfam PF03477 ATP cone domain 51 136 2.5E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SmaCSM2_RS04990 56582197ff0cdb1a6482b706db6cea5d 327 Gene3D G3DSA:3.20.20.100 1 326 1.6E-104 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS04990 56582197ff0cdb1a6482b706db6cea5d 327 Pfam PF00248 Aldo/keto reductase family 16 307 5.9E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS04990 56582197ff0cdb1a6482b706db6cea5d 327 SUPERFAMILY SSF51430 1 309 1.96E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS14670 45d8626bcf813de422ff4e14e9af6f16 301 Pfam PF01551 Peptidase family M23 199 294 1.0E-28 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS14670 45d8626bcf813de422ff4e14e9af6f16 301 Gene3D G3DSA:2.70.70.10 144 301 8.3E-43 T 28-03-2018 SmaCSM2_RS14670 45d8626bcf813de422ff4e14e9af6f16 301 SUPERFAMILY SSF51261 70 298 6.02E-54 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 152 3.5E-49 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 9.8E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 9.8E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 85 101 9.8E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 63 79 9.8E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 109 128 9.8E-37 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 156 8.2E-53 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 115 149 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 SUPERFAMILY SSF53098 3 156 2.2E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 155 43.853 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SmaCSM2_RS16715 1265dce1d59c17783eac107c72efa536 173 Gene3D G3DSA:3.30.420.10 2 161 8.7E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS07885 a7cea09ea65e8ed50ea65b6cfc8d831c 69 Gene3D G3DSA:1.10.260.40 6 65 1.1E-7 T 28-03-2018 SmaCSM2_RS07885 a7cea09ea65e8ed50ea65b6cfc8d831c 69 SUPERFAMILY SSF47413 19 58 7.31E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS17890 2017d6a01f9d40fd47255ddeb8920201 351 Gene3D G3DSA:3.40.190.10 187 321 3.3E-12 T 28-03-2018 SmaCSM2_RS17890 2017d6a01f9d40fd47255ddeb8920201 351 Gene3D G3DSA:3.40.190.10 1 167 1.2E-13 T 28-03-2018 SmaCSM2_RS17890 2017d6a01f9d40fd47255ddeb8920201 351 Pfam PF13531 Bacterial extracellular solute-binding protein 46 295 2.7E-19 T 28-03-2018 SmaCSM2_RS17890 2017d6a01f9d40fd47255ddeb8920201 351 SUPERFAMILY SSF53850 37 309 2.47E-43 T 28-03-2018 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 Hamap MF_00416 Flagellar P-ring protein [flgI]. 14 378 38.813 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 265 277 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 117 134 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 175 193 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 201 219 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 49 64 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 95 114 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 34 49 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 69 84 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 PRINTS PR01010 Flagellar P-ring protein signature 134 152 1.4E-79 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS10265 08e71e1b1f7592c4af80308febd845d2 378 Pfam PF02119 Flagellar P-ring protein 34 377 4.2E-137 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 SmaCSM2_RS15540 aa9638be410927421da8410b42ab9382 292 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SmaCSM2_RS15540 aa9638be410927421da8410b42ab9382 292 SUPERFAMILY SSF48576 7 285 4.48E-85 T 28-03-2018 IPR008949 Isoprenoid synthase domain SmaCSM2_RS15540 aa9638be410927421da8410b42ab9382 292 Gene3D G3DSA:1.10.600.10 2 292 2.1E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain SmaCSM2_RS15540 aa9638be410927421da8410b42ab9382 292 Pfam PF00348 Polyprenyl synthetase 31 263 1.1E-56 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SmaCSM2_RS15540 aa9638be410927421da8410b42ab9382 292 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 PRINTS PR01171 Bacterial lipocalin signature 30 44 1.5E-5 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 PRINTS PR01171 Bacterial lipocalin signature 123 131 1.5E-5 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 PRINTS PR01171 Bacterial lipocalin signature 138 149 1.5E-5 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 SUPERFAMILY SSF50814 11 173 5.17E-37 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 ProSitePatterns PS00213 Lipocalin signature. 31 42 - T 28-03-2018 IPR022272 Lipocalin family conserved site SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 PIRSF PIRSF036893 1 180 8.4E-55 T 28-03-2018 IPR022271 Lipocalin, ApoD type SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 Pfam PF08212 Lipocalin-like domain 30 174 2.6E-50 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain SmaCSM2_RS14850 6ffe40d1ea1aef5b117fea43b7e8a9b4 183 Gene3D G3DSA:2.40.128.20 6 176 2.0E-32 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 SMART SM01387 5 85 1.3E-50 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 7 85 3.0E-37 T 28-03-2018 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 SUPERFAMILY SSF47060 4 86 8.54E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 Gene3D G3DSA:1.10.287.10 1 86 5.1E-34 T 28-03-2018 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 Pfam PF00312 Ribosomal protein S15 6 85 1.1E-37 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 ProSitePatterns PS00362 Ribosomal protein S15 signature. 36 66 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 86 9.0E-38 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15070 990db4b7f905e73be11338b0aebd8c70 86 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 86 21.659 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 Pfam PF07883 Cupin domain 38 86 1.4E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 Gene3D G3DSA:2.60.120.10 23 92 1.6E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 SMART SM00342 179 261 4.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 Gene3D G3DSA:1.10.10.60 219 267 1.2E-10 T 28-03-2018 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 SUPERFAMILY SSF46689 217 265 5.38E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 Pfam PF12833 Helix-turn-helix domain 185 263 1.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 SUPERFAMILY SSF51182 10 181 4.15E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 7.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 7.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS18920 981c93eff6aa4567bf86605399026290 267 Gene3D G3DSA:1.10.10.60 159 215 5.9E-10 T 28-03-2018 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Gene3D G3DSA:3.30.565.10 217 369 4.2E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Gene3D G3DSA:1.10.287.130 149 216 4.5E-14 T 28-03-2018 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Gene3D G3DSA:3.40.50.2300 4 148 1.3E-32 T 28-03-2018 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Pfam PF00072 Response regulator receiver domain 18 129 1.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 222 6.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 366 1.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SUPERFAMILY SSF47384 141 223 3.34E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SMART SM00387 265 369 6.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SMART SM00388 155 222 2.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SUPERFAMILY SSF55874 211 367 2.29E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SUPERFAMILY SSF52172 14 153 1.57E-32 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09455 74f10c4a942b97f1f3da5ea6c1a80b77 377 SMART SM00448 15 129 3.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PIRSF PIRSF001467 2 155 7.3E-55 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 5 133 1.1E-47 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 Gene3D G3DSA:2.40.100.10 2 152 1.9E-59 T 28-03-2018 IPR029000 Cyclophilin-like domain SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 SUPERFAMILY SSF50891 4 133 4.38E-56 T 28-03-2018 IPR029000 Cyclophilin-like domain SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 3.2E-34 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 110 125 3.2E-34 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 3.2E-34 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 97 109 3.2E-34 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS04160 4ba4567eb11a46f0a8487cf2c808acae 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 82 97 3.2E-34 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Gene3D G3DSA:1.10.3090.10 120 405 1.8E-56 T 28-03-2018 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Pfam PF01966 HD domain 231 314 6.7E-5 T 28-03-2018 IPR006674 HD domain SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 150 213 1.7E-12 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 406 50.364 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 SUPERFAMILY SSF81891 121 403 2.09E-51 T 28-03-2018 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 SUPERFAMILY SSF81301 1 120 1.31E-30 T 28-03-2018 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Gene3D G3DSA:3.30.460.10 1 119 1.3E-32 T 28-03-2018 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 Pfam PF01743 Poly A polymerase head domain 3 123 4.3E-21 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SmaCSM2_RS18180 7e99ef086e2490bdfd4f9cd2aae90022 406 PIRSF PIRSF000813 1 406 4.8E-188 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 PRINTS PR00421 Thioredoxin family signature 72 83 1.1E-7 T 28-03-2018 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 PRINTS PR00421 Thioredoxin family signature 24 32 1.1E-7 T 28-03-2018 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 PRINTS PR00421 Thioredoxin family signature 32 41 1.1E-7 T 28-03-2018 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 SUPERFAMILY SSF52833 2 108 6.12E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 Gene3D G3DSA:3.40.30.10 1 109 2.0E-35 T 28-03-2018 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 107 2.7E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 Pfam PF00085 Thioredoxin 5 106 6.9E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 PIRSF PIRSF000077 2 108 7.4E-42 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SmaCSM2_RS19455 ec7dc12aadd534692d038b5d01b69d57 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Gene3D G3DSA:3.20.20.450 426 682 7.8E-103 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Gene3D G3DSA:3.30.70.270 256 425 1.2E-61 T 28-03-2018 SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 SUPERFAMILY SSF55073 268 425 2.04E-50 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Pfam PF00990 Diguanylate cyclase, GGDEF domain 263 418 1.9E-49 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 261 421 3.3E-44 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 SUPERFAMILY SSF141868 439 682 1.26E-90 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Pfam PF03707 Bacterial signalling protein N terminal repeat 181 246 1.1E-10 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Pfam PF03707 Bacterial signalling protein N terminal repeat 114 165 4.1E-15 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Pfam PF03707 Bacterial signalling protein N terminal repeat 51 109 2.9E-21 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 SMART SM00052 433 679 1.8E-119 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 Pfam PF00563 EAL domain 439 674 2.0E-74 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06020 07d39fd19a46b4459fb50a67db5df8b4 685 SMART SM00267 252 423 1.6E-61 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Gene3D G3DSA:3.10.580.10 268 332 1.4E-13 T 28-03-2018 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 SMART SM00116 284 332 0.001 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 SMART SM00116 219 267 4.3E-4 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 PIRSF PIRSF004692 6 333 8.6E-134 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Pfam PF00571 CBS domain 211 267 6.6E-8 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Pfam PF00571 CBS domain 278 331 2.5E-8 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 54 323 2.2E-110 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 SUPERFAMILY SSF53697 22 330 4.0E-70 T 28-03-2018 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Gene3D G3DSA:3.40.50.10490 11 208 4.3E-54 T 28-03-2018 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Gene3D G3DSA:3.10.580.10 209 267 1.6E-9 T 28-03-2018 SmaCSM2_RS05125 706e42969e3e4d0ba554e262e49c503e 333 Pfam PF01380 SIS domain 50 181 5.5E-31 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 SUPERFAMILY SSF51905 4 176 1.2E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 SUPERFAMILY SSF51905 266 382 1.2E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 388 9.2E-114 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 Gene3D G3DSA:3.50.50.60 1 363 2.5E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 Pfam PF01494 FAD binding domain 4 319 1.0E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.4E-13 T 28-03-2018 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.4E-13 T 28-03-2018 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.4E-13 T 28-03-2018 SmaCSM2_RS06430 f69fe2f8289aa065f2a1112a48572f73 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.4E-13 T 28-03-2018 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 6.1E-20 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 Pfam PF01037 Lrp/AsnC ligand binding domain 74 148 1.6E-20 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 Gene3D G3DSA:1.10.10.10 9 60 2.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 1.8E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 1.8E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 1.8E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 Gene3D G3DSA:3.30.70.920 61 154 1.5E-24 T 28-03-2018 SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 SUPERFAMILY SSF54909 70 157 2.95E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 SUPERFAMILY SSF46785 7 65 6.39E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02420 02ad0ea32d4440d904ca1e98eb921a40 159 SMART SM00344 8 117 1.2E-43 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 Gene3D G3DSA:3.40.630.10 268 541 3.9E-37 T 28-03-2018 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 Pfam PF04389 Peptidase family M28 314 531 5.1E-48 T 28-03-2018 IPR007484 Peptidase M28 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 Pfam PF02225 PA domain 148 238 1.3E-6 T 28-03-2018 IPR003137 PA domain SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 SUPERFAMILY SSF52025 147 234 4.97E-5 T 28-03-2018 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 SUPERFAMILY SSF53187 42 92 3.43E-64 T 28-03-2018 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 SUPERFAMILY SSF53187 298 542 3.43E-64 T 28-03-2018 SmaCSM2_RS01730 ef80ecd170a183c738f3a97801593744 569 Gene3D G3DSA:3.50.30.30 121 267 1.6E-14 T 28-03-2018 SmaCSM2_RS00465 c60939e063d7f5d3054c0161874a4573 339 Pfam PF13482 RNase_H superfamily 149 323 3.0E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS00465 c60939e063d7f5d3054c0161874a4573 339 Gene3D G3DSA:3.30.420.10 148 336 1.5E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS00465 c60939e063d7f5d3054c0161874a4573 339 SUPERFAMILY SSF53098 144 334 4.56E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:1.10.1670.10 436 488 1.7E-15 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:1.10.10.60 82 139 1.3E-8 T 28-03-2018 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:3.40.10.10 1 77 1.4E-24 T 28-03-2018 IPR035451 Ada-like domain SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SUPERFAMILY SSF57884 5 85 1.07E-30 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 140 182 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SUPERFAMILY SSF46689 88 134 6.27E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Pfam PF06029 AlkA N-terminal domain 200 317 5.5E-34 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SUPERFAMILY SSF46689 140 190 7.62E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Pfam PF12833 Helix-turn-helix domain 109 188 1.1E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 323 470 3.4E-11 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SUPERFAMILY SSF55945 200 298 1.33E-24 T 28-03-2018 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SUPERFAMILY SSF48150 307 483 5.76E-44 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:1.10.10.60 140 195 4.7E-12 T 28-03-2018 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Pfam PF02805 Metal binding domain of Ada 12 75 1.3E-26 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:3.30.310.20 200 313 2.2E-34 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SMART SM00478 327 485 1.4E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SMART SM00342 103 186 4.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 Gene3D G3DSA:1.10.340.30 314 434 2.8E-22 T 28-03-2018 SmaCSM2_RS06410 47261ee7b3d2f383de846e04e2333fa7 492 SMART SM01009 200 317 1.8E-44 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Pfam PF00271 Helicase conserved C-terminal domain 815 914 2.1E-16 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SMART SM00487 605 801 2.1E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SMART SM01058 484 581 5.4E-49 T 28-03-2018 IPR003711 CarD-like/TRCF domain SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Gene3D G3DSA:3.30.2060.10 136 184 0.0012 T 28-03-2018 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 153 1088 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF52540 21 345 1.98E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Pfam PF03461 TRCF domain 1015 1107 1.4E-27 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF52540 528 789 1.33E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Pfam PF02559 CarD-like/TRCF domain 485 578 1.3E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SMART SM00982 1014 1114 2.0E-50 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF52540 787 995 4.51E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Gene3D G3DSA:3.40.50.300 793 961 5.3E-24 T 28-03-2018 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Pfam PF00270 DEAD/DEAH box helicase 610 767 1.2E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Gene3D G3DSA:3.40.50.300 445 782 3.8E-38 T 28-03-2018 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF141259 476 553 9.94E-22 T 28-03-2018 IPR003711 CarD-like/TRCF domain SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 34 1113 29.089 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SMART SM00490 831 915 2.5E-19 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF52540 358 470 1.59E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06320 ede14548a5661f43061911e7e3fd47b3 1154 SUPERFAMILY SSF143517 1006 1152 1.7E-42 T 28-03-2018 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 Gene3D G3DSA:1.10.8.60 317 407 1.0E-21 T 28-03-2018 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 SUPERFAMILY SSF46689 394 445 1.6E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 SMART SM00382 164 308 8.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 Pfam PF00158 Sigma-54 interaction domain 144 310 1.7E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 SUPERFAMILY SSF52540 144 386 2.66E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 Pfam PF02954 Bacterial regulatory protein, Fis family 405 438 1.9E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 Gene3D G3DSA:1.10.10.60 408 447 6.9E-10 T 28-03-2018 SmaCSM2_RS11535 136bedc50f95c48c8959068c0f06c60f 451 Gene3D G3DSA:3.40.50.300 140 316 4.9E-27 T 28-03-2018 SmaCSM2_RS21710 1854c70eb30093e408b34ef23ae6db90 475 Pfam PF13520 Amino acid permease 25 442 1.5E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS21710 1854c70eb30093e408b34ef23ae6db90 475 PIRSF PIRSF006060 7 473 1.5E-81 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Pfam PF02272 DHHA1 domain 740 878 5.6E-26 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 882 198.793 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 SUPERFAMILY SSF55681 7 257 7.46E-107 T 28-03-2018 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 660 703 1.5E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Gene3D G3DSA:3.30.980.10 560 720 5.3E-46 T 28-03-2018 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Gene3D G3DSA:3.30.930.10 6 254 4.6E-115 T 28-03-2018 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 SMART SM00863 660 703 6.5E-23 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 SUPERFAMILY SSF50447 459 558 5.3E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 Pfam PF01411 tRNA synthetases class II (A) 11 563 1.7E-218 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 211 222 4.7E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 238 251 4.7E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 284 300 4.7E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 80 91 4.7E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 308 321 4.7E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 12 861 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 SUPERFAMILY SSF101353 258 448 2.48E-61 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SmaCSM2_RS08155 7411eb185958298e68b69d3c73084759 882 SUPERFAMILY SSF55186 559 718 1.83E-53 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SmaCSM2_RS20190 cb972d183f9accf43f762689b080aa31 80 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 55 2.1E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20190 cb972d183f9accf43f762689b080aa31 80 SUPERFAMILY SSF46785 10 57 2.39E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20190 cb972d183f9accf43f762689b080aa31 80 Gene3D G3DSA:1.10.10.10 7 67 2.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10070 c9bfc647945ae3888790f2660514ec4b 246 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 219 1.3E-25 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS12675 a925a5c1155983d8bf6fb76b775f559e 238 Pfam PF02308 MgtC family 19 140 1.9E-33 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12675 a925a5c1155983d8bf6fb76b775f559e 238 PRINTS PR01837 MgtC/SapB protein signature 41 59 4.5E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12675 a925a5c1155983d8bf6fb76b775f559e 238 PRINTS PR01837 MgtC/SapB protein signature 94 118 4.5E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12675 a925a5c1155983d8bf6fb76b775f559e 238 PRINTS PR01837 MgtC/SapB protein signature 67 89 4.5E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12675 a925a5c1155983d8bf6fb76b775f559e 238 PRINTS PR01837 MgtC/SapB protein signature 22 41 4.5E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 211 8.6E-32 T 28-03-2018 SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 Gene3D G3DSA:3.40.50.720 1 272 1.5E-51 T 28-03-2018 SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 SUPERFAMILY SSF51735 3 243 8.3E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17565 19f6d6c21e2fe2a2a14fa5932953dc30 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.0E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 Gene3D G3DSA:2.140.10.30 263 541 1.1E-10 T 28-03-2018 SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 Gene3D G3DSA:2.140.10.30 30 262 5.4E-12 T 28-03-2018 SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 SUPERFAMILY SSF53474 568 826 7.27E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 SUPERFAMILY SSF82171 112 205 1.31E-21 T 28-03-2018 SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 SUPERFAMILY SSF82171 245 545 1.31E-21 T 28-03-2018 SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 Gene3D G3DSA:3.40.50.1820 542 836 3.8E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03370 85f76077dd5e74db351d8aedfc666669 838 Pfam PF00326 Prolyl oligopeptidase family 669 827 1.9E-22 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 Pfam PF00326 Prolyl oligopeptidase family 594 789 2.5E-44 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 SUPERFAMILY SSF82171 98 162 2.22E-35 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 SUPERFAMILY SSF82171 234 253 2.22E-35 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 SUPERFAMILY SSF82171 286 308 2.22E-35 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 SUPERFAMILY SSF82171 339 533 2.22E-35 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 342 502 1.6E-16 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 Gene3D G3DSA:2.140.10.30 162 523 7.6E-50 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 Gene3D G3DSA:2.140.10.30 28 161 0.0027 T 28-03-2018 SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 SUPERFAMILY SSF53474 532 789 7.41E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS21175 00e2f635024e5112d807685866b73d18 789 Gene3D G3DSA:3.40.50.1820 524 789 6.3E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 Gene3D G3DSA:1.10.510.10 256 378 6.4E-4 T 28-03-2018 SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 12 446 5.4E-151 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 Pfam PF03109 ABC1 family 119 237 2.8E-33 T 28-03-2018 IPR004147 UbiB domain SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 SUPERFAMILY SSF56112 205 436 1.5E-25 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 SUPERFAMILY SSF56112 101 164 1.5E-25 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS08135 965535e567ffc604bf2fc5cdc7e81c1a 560 Gene3D G3DSA:3.30.200.20 108 250 6.0E-22 T 28-03-2018 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 SUPERFAMILY SSF46894 141 210 3.74E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 1.6E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 Pfam PF00072 Response regulator receiver domain 10 121 1.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 Gene3D G3DSA:1.10.10.10 145 215 8.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 SMART SM00421 146 203 2.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 SMART SM00448 8 121 1.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 SUPERFAMILY SSF52172 7 129 2.56E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS12825 73520a8cad09a4142b277fe0f0002f27 217 Gene3D G3DSA:3.40.50.2300 7 144 1.9E-36 T 28-03-2018 SmaCSM2_RS07475 0c0e8108beabeb08698444e5f40ee0e7 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 126 2.3E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS07475 0c0e8108beabeb08698444e5f40ee0e7 132 Gene3D G3DSA:3.10.180.10 5 131 3.1E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS07475 0c0e8108beabeb08698444e5f40ee0e7 132 SUPERFAMILY SSF54593 12 130 1.25E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS17775 8d76881ed124d0d60bdec668827b6dfc 192 Pfam PF00694 Aconitase C-terminal domain 1 123 9.7E-26 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS17775 8d76881ed124d0d60bdec668827b6dfc 192 SUPERFAMILY SSF52016 3 177 1.65E-51 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS17775 8d76881ed124d0d60bdec668827b6dfc 192 Gene3D G3DSA:3.20.19.10 1 171 6.5E-42 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS17775 8d76881ed124d0d60bdec668827b6dfc 192 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 177 6.7E-56 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 SMART SM00347 43 144 7.8E-26 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 Pfam PF12802 MarR family 49 108 2.7E-11 T 28-03-2018 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 SUPERFAMILY SSF46785 21 157 3.02E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 Gene3D G3DSA:1.10.10.10 1 161 4.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 6.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 6.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 6.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19190 25bdd7673f1ae4c84316cd5389ae44e9 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 6.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS00450 4e47a5ba9f5465560aa6a148ad67b6f8 128 Pfam PF03965 Penicillinase repressor 6 119 8.2E-26 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SmaCSM2_RS00450 4e47a5ba9f5465560aa6a148ad67b6f8 128 Gene3D G3DSA:1.10.10.10 1 70 2.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00450 4e47a5ba9f5465560aa6a148ad67b6f8 128 SUPERFAMILY SSF46785 4 121 5.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00450 4e47a5ba9f5465560aa6a148ad67b6f8 128 Gene3D G3DSA:1.10.4040.10 74 120 7.9E-10 T 28-03-2018 SmaCSM2_RS00450 4e47a5ba9f5465560aa6a148ad67b6f8 128 PIRSF PIRSF019455 1 128 3.2E-23 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 Gene3D G3DSA:3.30.565.10 300 440 1.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SMART SM00388 227 292 6.6E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SUPERFAMILY SSF55874 293 436 2.36E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 Gene3D G3DSA:1.10.287.130 217 287 1.2E-9 T 28-03-2018 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SMART SM00304 174 226 1.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 437 7.4E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 4.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 4.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 4.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SUPERFAMILY SSF158472 175 225 2.48E-5 T 28-03-2018 SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SMART SM00387 332 438 1.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02570 066326ef6022baf3649c19b37368eb6d 448 SUPERFAMILY SSF47384 210 287 8.04E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 190 208 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 184 196 7.1E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 114 130 7.1E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 104 7.1E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 215 227 7.1E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 Hamap MF_01974 Methionine aminopeptidase [map]. 25 273 42.569 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 Pfam PF00557 Metallopeptidase family M24 34 264 6.1E-55 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 SUPERFAMILY SSF55920 27 275 3.53E-95 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 26 272 1.8E-98 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SmaCSM2_RS06685 0789cda814afb5d7e61900a841852b2c 280 Gene3D G3DSA:3.90.230.10 22 279 1.8E-89 T 28-03-2018 SmaCSM2_RS07325 519542e636100a8572dbe2ddd1ffd587 257 Gene3D G3DSA:3.90.550.10 2 256 5.4E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS07325 519542e636100a8572dbe2ddd1ffd587 257 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 4 245 1.9E-79 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 SmaCSM2_RS07325 519542e636100a8572dbe2ddd1ffd587 257 Pfam PF02348 Cytidylyltransferase 6 222 1.5E-43 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 SmaCSM2_RS07325 519542e636100a8572dbe2ddd1ffd587 257 SUPERFAMILY SSF53448 4 250 5.88E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS07325 519542e636100a8572dbe2ddd1ffd587 257 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 2 252 38.605 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 PIRSF PIRSF000164 14 345 1.5E-95 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 336 50.982 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 340 1.0E-129 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 SUPERFAMILY SSF51395 1 338 2.5E-102 T 28-03-2018 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 Pfam PF01180 Dihydroorotate dehydrogenase 46 337 9.5E-92 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SmaCSM2_RS09360 4d2127d064752c1203b7b69350338baf 351 Gene3D G3DSA:3.20.20.70 1 341 1.9E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS19515 ec88022de70d8c5d70d6a86353a411f9 97 Pfam PF01476 LysM domain 47 95 7.6E-15 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS19515 ec88022de70d8c5d70d6a86353a411f9 97 SMART SM00257 46 95 1.7E-11 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS19515 ec88022de70d8c5d70d6a86353a411f9 97 Gene3D G3DSA:3.10.350.10 44 96 9.2E-18 T 28-03-2018 SmaCSM2_RS19515 ec88022de70d8c5d70d6a86353a411f9 97 SUPERFAMILY SSF54106 45 95 1.7E-8 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS16725 f9e3394e3d0f21d94bcede9439f5dd69 210 SUPERFAMILY SSF53474 3 169 4.89E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16725 f9e3394e3d0f21d94bcede9439f5dd69 210 Gene3D G3DSA:3.40.50.1820 2 203 1.6E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11955 f8640eaf056370b60d8c6ec046fa12df 415 Gene3D G3DSA:1.20.1600.10 7 409 1.6E-48 T 28-03-2018 SmaCSM2_RS11955 f8640eaf056370b60d8c6ec046fa12df 415 SUPERFAMILY SSF56954 4 407 2.62E-60 T 28-03-2018 SmaCSM2_RS11955 f8640eaf056370b60d8c6ec046fa12df 415 Pfam PF02321 Outer membrane efflux protein 238 407 8.3E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS11955 f8640eaf056370b60d8c6ec046fa12df 415 Pfam PF02321 Outer membrane efflux protein 25 210 6.2E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS00550 ff6554af38a1be2bae8daa6e9d7d8b17 211 Gene3D G3DSA:1.25.40.10 16 120 4.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00550 ff6554af38a1be2bae8daa6e9d7d8b17 211 Gene3D G3DSA:1.25.40.10 121 185 0.0014 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS00550 ff6554af38a1be2bae8daa6e9d7d8b17 211 SUPERFAMILY SSF48452 68 193 5.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 SUPERFAMILY SSF52540 304 523 5.82E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 Gene3D G3DSA:3.40.50.300 8 290 2.5E-53 T 28-03-2018 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 Gene3D G3DSA:3.40.50.300 291 547 1.3E-56 T 28-03-2018 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 Pfam PF00005 ABC transporter 24 192 8.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 Pfam PF00005 ABC transporter 341 474 3.8E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 Pfam PF12848 ABC transporter 231 307 1.8E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 SUPERFAMILY SSF52540 10 238 1.15E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 553 1.1E-287 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 SMART SM00382 349 527 6.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS03085 00a17ed399f7369368b3a82037d59109 554 SMART SM00382 32 237 3.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 8.0E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 Gene3D G3DSA:3.40.190.10 180 269 2.7E-13 T 28-03-2018 SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 SUPERFAMILY SSF53850 92 294 3.44E-29 T 28-03-2018 SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 Gene3D G3DSA:3.40.190.10 91 179 3.8E-8 T 28-03-2018 SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 SUPERFAMILY SSF46785 2 83 1.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 Gene3D G3DSA:1.10.10.10 1 89 5.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18010 c9ed977b1fc6892f5c3b331296926d9e 305 Pfam PF03466 LysR substrate binding domain 93 296 4.2E-15 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Pfam PF13202 EF hand 51 68 3.6E-5 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Pfam PF13202 EF hand 27 44 0.0034 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Pfam PF13202 EF hand 89 106 0.0033 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 ProSitePatterns PS00018 EF-hand calcium-binding domain. 93 105 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Gene3D G3DSA:1.10.238.10 20 54 9.2E-9 T 28-03-2018 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 ProSitePatterns PS00018 EF-hand calcium-binding domain. 32 44 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 SUPERFAMILY SSF47473 27 106 1.22E-13 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 ProSitePatterns PS00018 EF-hand calcium-binding domain. 56 68 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Gene3D G3DSA:1.10.238.10 91 107 0.092 T 28-03-2018 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Gene3D G3DSA:1.10.238.10 55 63 0.0052 T 28-03-2018 SmaCSM2_RS00300 4aee59c3fe323e6bd311714102f5563c 110 Gene3D G3DSA:1.10.238.10 64 90 2.0E-5 T 28-03-2018 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 4.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 Gene3D G3DSA:1.10.10.60 3 45 4.0E-12 T 28-03-2018 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 Gene3D G3DSA:1.10.260.40 46 66 1.4E-5 T 28-03-2018 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 Gene3D G3DSA:1.10.357.10 67 185 1.6E-7 T 28-03-2018 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 SUPERFAMILY SSF48498 77 181 6.36E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS06380 72d1ea5f06767a26b8aaf08aa4836b83 188 SUPERFAMILY SSF46689 4 82 1.65E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:3.30.70.1430 552 657 0.0018 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82714 184 265 9.02E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:1.20.1640.10 282 503 1.4E-35 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:3.30.70.1430 40 144 1.3E-23 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:3.30.2090.10 181 268 7.9E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:1.20.1640.10 792 1008 1.4E-39 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82866 792 1009 1.57E-44 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Pfam PF00873 AcrB/AcrD/AcrF family 4 1005 1.0E-166 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 537 554 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.9E-32 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82693 40 133 2.09E-15 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82714 706 790 1.44E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82866 293 489 1.31E-37 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82693 138 182 4.6E-18 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 SUPERFAMILY SSF82693 269 324 4.6E-18 T 28-03-2018 SmaCSM2_RS11230 c9257892b468237d529da99ee1d2c3ef 1015 Gene3D G3DSA:3.30.2090.10 705 791 7.7E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS05535 24bcda7bbfb19ffde6a00d5575be8e87 580 SUPERFAMILY SSF55073 419 573 2.43E-45 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS05535 24bcda7bbfb19ffde6a00d5575be8e87 580 Gene3D G3DSA:3.30.70.270 407 577 2.1E-52 T 28-03-2018 SmaCSM2_RS05535 24bcda7bbfb19ffde6a00d5575be8e87 580 Pfam PF00990 Diguanylate cyclase, GGDEF domain 415 569 8.4E-42 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05535 24bcda7bbfb19ffde6a00d5575be8e87 580 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 411 572 3.3E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05535 24bcda7bbfb19ffde6a00d5575be8e87 580 SMART SM00267 403 573 1.5E-58 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS15210 9cc72d95fd05ad675a786cd0f1a10c7a 285 SUPERFAMILY SSF88713 20 100 1.29E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS15210 9cc72d95fd05ad675a786cd0f1a10c7a 285 SUPERFAMILY SSF88713 139 249 1.29E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS15210 9cc72d95fd05ad675a786cd0f1a10c7a 285 Pfam PF01522 Polysaccharide deacetylase 56 223 1.3E-34 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SmaCSM2_RS15210 9cc72d95fd05ad675a786cd0f1a10c7a 285 Gene3D G3DSA:3.20.20.370 6 280 1.0E-47 T 28-03-2018 SmaCSM2_RS17250 c192c23c1dc4a4449566563f9132feee 334 Gene3D G3DSA:3.40.50.410 94 314 1.5E-44 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17250 c192c23c1dc4a4449566563f9132feee 334 SMART SM00327 98 297 4.3E-28 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17250 c192c23c1dc4a4449566563f9132feee 334 SUPERFAMILY SSF53300 95 293 2.08E-39 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17250 c192c23c1dc4a4449566563f9132feee 334 Pfam PF00092 von Willebrand factor type A domain 101 290 8.1E-27 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17950 248777f76c78bd7e18ed648cf3bbd197 259 Gene3D G3DSA:3.20.20.370 65 255 3.7E-39 T 28-03-2018 SmaCSM2_RS17950 248777f76c78bd7e18ed648cf3bbd197 259 Pfam PF01522 Polysaccharide deacetylase 73 193 1.4E-28 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SmaCSM2_RS17950 248777f76c78bd7e18ed648cf3bbd197 259 SUPERFAMILY SSF88713 57 253 1.48E-48 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 Pfam PF07687 Peptidase dimerisation domain 207 367 7.5E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 SUPERFAMILY SSF53187 383 468 1.09E-49 T 28-03-2018 SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 SUPERFAMILY SSF53187 12 209 1.09E-49 T 28-03-2018 SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 Pfam PF01546 Peptidase family M20/M25/M40 95 466 5.3E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 Gene3D G3DSA:3.40.630.10 10 212 1.2E-23 T 28-03-2018 SmaCSM2_RS05210 9e903d9e88caec2faaa6d6e31c61f125 497 Gene3D G3DSA:3.30.70.360 213 379 1.4E-35 T 28-03-2018 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 Gene3D G3DSA:1.10.10.10 136 241 7.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 SMART SM00448 5 117 1.0E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 SUPERFAMILY SSF52172 5 134 1.41E-41 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 SUPERFAMILY SSF46894 136 236 6.8E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 Gene3D G3DSA:3.40.50.2300 5 135 2.2E-39 T 28-03-2018 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 Pfam PF00072 Response regulator receiver domain 7 118 5.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 SMART SM00862 159 235 3.7E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS05635 7bfbaf84a35e26a108159e9ddb3d1015 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 235 6.7E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS21515 b43f84af9c65d186742051e2fe558c56 395 Pfam PF03594 Benzoate membrane transport protein 12 387 4.3E-145 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 SmaCSM2_RS21515 b43f84af9c65d186742051e2fe558c56 395 TIGRFAM TIGR00843 benE: benzoate transporter 14 389 1.9E-135 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 198 356 7.2E-12 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 363 2.7E-144 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 SUPERFAMILY SSF52540 198 363 1.75E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Pfam PF16360 GTP-binding GTPase Middle Region 113 192 4.4E-27 T 28-03-2018 IPR032305 GTP-binding protein, middle domain SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 PIRSF PIRSF006809 3 423 1.3E-141 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Hamap MF_00900 GTPase HflX [hflX]. 26 393 46.907 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Gene3D G3DSA:3.40.50.300 165 229 3.0E-15 T 28-03-2018 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Pfam PF13167 GTP-binding GTPase N-terminal 25 111 5.0E-29 T 28-03-2018 IPR025121 GTPase HflX, N-terminal SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Gene3D G3DSA:3.40.50.300 230 357 1.4E-14 T 28-03-2018 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 266 284 4.6E-12 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 4.6E-12 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 4.6E-12 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS08125 889e40f8329ae6f5a1153a2f070e926b 436 Pfam PF01926 50S ribosome-binding GTPase 199 317 4.7E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Gene3D G3DSA:3.40.50.2300 72 193 1.0E-20 T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Gene3D G3DSA:3.40.50.2300 194 326 1.8E-41 T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 SMART SM00354 18 88 2.4E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 SUPERFAMILY SSF47413 18 76 2.16E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 SUPERFAMILY SSF53822 79 347 1.88E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Gene3D G3DSA:1.10.260.40 34 71 1.4E-19 T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Gene3D G3DSA:1.10.10.60 9 33 5.1E-4 T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 30 40 1.8E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 1.8E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Pfam PF13377 Periplasmic binding protein-like domain 188 346 3.0E-34 T 28-03-2018 SmaCSM2_RS00245 9047fed1c51704d889fd617d77ff90bb 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 65 9.0E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 SUPERFAMILY SSF47384 197 274 1.06E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 SUPERFAMILY SSF55874 263 425 4.06E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 SMART SM00388 210 274 6.3E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 SMART SM00387 317 429 3.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Gene3D G3DSA:3.30.565.10 287 443 8.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Pfam PF11808 Domain of unknown function (DUF3329) 8 94 9.5E-21 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Gene3D G3DSA:3.30.450.20 100 215 8.6E-11 T 28-03-2018 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 98 425 2.6E-125 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 273 1.0E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 SUPERFAMILY SSF55785 88 158 4.71E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Gene3D G3DSA:1.10.287.130 216 270 1.7E-17 T 28-03-2018 SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Pfam PF13188 PAS domain 103 151 1.8E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS04325 5f49056f2abbd84748fddf85e6414b7e 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 427 1.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09265 372d106a491e41ef8376378255ebc175 447 Pfam PF00296 Luciferase-like monooxygenase 20 383 1.4E-63 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS09265 372d106a491e41ef8376378255ebc175 447 Gene3D G3DSA:3.20.20.30 1 445 2.0E-104 T 28-03-2018 SmaCSM2_RS09265 372d106a491e41ef8376378255ebc175 447 SUPERFAMILY SSF51679 5 431 2.62E-129 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS09265 372d106a491e41ef8376378255ebc175 447 PIRSF PIRSF000337 3 441 2.2E-139 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SmaCSM2_RS09265 372d106a491e41ef8376378255ebc175 447 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 426 2.9E-155 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 SUPERFAMILY SSF56176 207 291 2.67E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 Pfam PF03471 Transporter associated domain 210 285 5.4E-21 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 Gene3D G3DSA:3.10.580.10 50 196 4.6E-34 T 28-03-2018 SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 Gene3D G3DSA:3.30.465.10 197 286 4.3E-25 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 Pfam PF00571 CBS domain 141 190 2.5E-4 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 Pfam PF00571 CBS domain 70 125 3.2E-6 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 SMART SM01091 208 286 5.2E-27 T 28-03-2018 IPR005170 Transporter-associated domain SmaCSM2_RS07075 a65827e9925653fd0f029c4ccea433a4 293 SUPERFAMILY SSF54631 67 203 2.78E-31 T 28-03-2018 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 14 469 5.2E-161 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 Pfam PF06969 HemN C-terminal domain 375 442 3.4E-8 T 28-03-2018 IPR010723 HemN, C-terminal SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 Pfam PF04055 Radical SAM superfamily 66 240 1.0E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 Gene3D G3DSA:3.20.20.70 36 364 5.1E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 SUPERFAMILY SSF102114 13 456 6.02E-132 T 28-03-2018 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 PIRSF PIRSF000167 14 467 1.5E-157 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 SmaCSM2_RS07910 fd2eb3eaea0debe50499a034f026b9a2 469 SMART SM00729 61 284 8.0E-50 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS13930 aa50816b7f2338c8006065b25defaf35 212 SUPERFAMILY SSF50475 9 200 1.33E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS13930 aa50816b7f2338c8006065b25defaf35 212 PIRSF PIRSF010372 1 207 5.2E-40 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SmaCSM2_RS13930 aa50816b7f2338c8006065b25defaf35 212 Pfam PF04299 Putative FMN-binding domain 1 163 2.1E-37 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SmaCSM2_RS13930 aa50816b7f2338c8006065b25defaf35 212 Gene3D G3DSA:2.30.110.10 1 205 1.3E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS08935 beac68d16db541a29464ba49f678fc32 129 SUPERFAMILY SSF46626 37 127 3.58E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08935 beac68d16db541a29464ba49f678fc32 129 Gene3D G3DSA:1.10.760.10 19 128 7.6E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08935 beac68d16db541a29464ba49f678fc32 129 Pfam PF00034 Cytochrome c 53 129 6.6E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 SUPERFAMILY SSF46689 229 273 8.06E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 Pfam PF12833 Helix-turn-helix domain 201 273 1.2E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 Gene3D G3DSA:2.60.120.10 31 210 0.0014 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 Gene3D G3DSA:1.10.10.60 221 274 7.1E-9 T 28-03-2018 SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 SMART SM00342 193 274 5.2E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS18095 00353137d9d1263d6b7b86679c8ea191 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10055 300aa681554a843ea282e342cb2d3a37 411 SMART SM00260 272 410 1.2E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10055 300aa681554a843ea282e342cb2d3a37 411 Gene3D G3DSA:2.40.50.180 293 356 8.6E-17 T 28-03-2018 SmaCSM2_RS10055 300aa681554a843ea282e342cb2d3a37 411 SUPERFAMILY SSF50341 273 411 4.19E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS10055 300aa681554a843ea282e342cb2d3a37 411 Gene3D G3DSA:2.30.30.40 357 404 3.0E-12 T 28-03-2018 SmaCSM2_RS10055 300aa681554a843ea282e342cb2d3a37 411 Pfam PF01584 CheW-like domain 278 410 1.3E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 SUPERFAMILY SSF51735 1 255 7.89E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 9.1E-40 T 28-03-2018 SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 Gene3D G3DSA:3.40.50.720 1 253 8.1E-54 T 28-03-2018 SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20660 a740a2428f47d46781c24161c84d9110 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 Gene3D G3DSA:2.40.170.20 173 932 2.3E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 Gene3D G3DSA:2.170.130.10 31 172 7.2E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 Pfam PF00593 TonB dependent receptor 362 930 6.9E-30 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 SUPERFAMILY SSF56935 39 237 9.46E-84 T 28-03-2018 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 SUPERFAMILY SSF56935 385 487 9.46E-84 T 28-03-2018 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 SUPERFAMILY SSF56935 308 356 9.46E-84 T 28-03-2018 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 SUPERFAMILY SSF56935 523 699 9.46E-84 T 28-03-2018 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 SUPERFAMILY SSF56935 730 932 9.46E-84 T 28-03-2018 SmaCSM2_RS15430 4eb9000f70ecab461e3c3979c1d4245d 935 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 170 1.6E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Gene3D G3DSA:1.20.1180.10 198 263 6.3E-21 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 SUPERFAMILY SSF51161 2 262 2.36E-70 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Gene3D G3DSA:2.160.10.10 1 190 1.9E-43 T 28-03-2018 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 261 1.5E-100 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 263 44.271 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 260 2.5E-25 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 PIRSF PIRSF000456 5 263 3.3E-95 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 4.2E-5 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06590 efd029de766e7da5e4f6730d351a7c34 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 21 45 3.0E-4 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 SUPERFAMILY SSF110942 514 626 3.4E-34 T 28-03-2018 SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 Gene3D G3DSA:3.30.565.10 1 228 4.3E-51 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 Pfam PF00183 Hsp90 protein 224 625 5.3E-126 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 SMART SM00387 30 187 3.0E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 185 1.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 626 31.844 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 SUPERFAMILY SSF55874 7 216 1.57E-63 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PIRSF PIRSF002583 1 630 2.1E-205 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 29 51 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 193 211 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 96 113 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 175 192 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 78 95 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 8 28 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 PRINTS PR00775 90kDa heat shock protein signature 123 145 5.2E-60 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 SmaCSM2_RS08500 321e87b860e329b1448677f6a038a51c 630 SUPERFAMILY SSF54211 232 487 6.14E-94 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Gene3D G3DSA:1.25.40.10 410 473 1.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Gene3D G3DSA:1.25.40.10 495 563 1.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Gene3D G3DSA:1.25.40.10 207 409 2.5E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Gene3D G3DSA:1.25.40.10 40 206 7.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Pfam PF13432 Tetratricopeptide repeat 186 235 0.0035 T 28-03-2018 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Pfam PF13432 Tetratricopeptide repeat 462 512 1.3E-4 T 28-03-2018 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SMART SM00028 417 450 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SMART SM00028 519 552 0.081 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SMART SM00028 179 212 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SMART SM00028 451 485 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SUPERFAMILY SSF48452 403 553 5.16E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Gene3D G3DSA:1.25.40.10 474 494 4.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 SUPERFAMILY SSF48452 176 336 2.95E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03815 37d26c104247ca157dbd1ce6d14fc657 564 Pfam PF13181 Tetratricopeptide repeat 526 552 0.084 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS19850 db4f88bc13d18c65038e054baba8bc87 235 Pfam PF08279 HTH domain 6 60 5.6E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SmaCSM2_RS19850 db4f88bc13d18c65038e054baba8bc87 235 Gene3D G3DSA:1.10.10.10 1 63 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19850 db4f88bc13d18c65038e054baba8bc87 235 SUPERFAMILY SSF46785 3 63 2.45E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19850 db4f88bc13d18c65038e054baba8bc87 235 Pfam PF13280 WYL domain 138 229 9.6E-18 T 28-03-2018 IPR026881 WYL domain SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 160 6.0E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 SUPERFAMILY SSF56935 23 703 2.02E-123 T 28-03-2018 SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 Gene3D G3DSA:2.170.130.10 21 171 2.8E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 Gene3D G3DSA:2.40.170.20 174 703 3.0E-70 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 Pfam PF00593 TonB dependent receptor 279 699 2.7E-47 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04865 88009d1ce1c20a16eec946c4783b20de 703 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 60 703 6.7E-83 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 Pfam PF03313 Serine dehydratase alpha chain 189 454 1.2E-105 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 Gene3D G3DSA:3.30.1330.90 11 161 2.5E-55 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 SUPERFAMILY SSF143548 17 158 5.75E-44 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 Gene3D G3DSA:1.10.4100.10 269 449 6.6E-33 T 28-03-2018 SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 457 1.4E-216 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SmaCSM2_RS16295 fe73c06f133ba427d34ea9291d3052d4 460 Pfam PF03315 Serine dehydratase beta chain 4 158 2.3E-58 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SmaCSM2_RS03750 4d6388360d2e6a991dc91b40de1e3f1f 183 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 10 182 1.8E-82 T 28-03-2018 IPR017776 FeS assembly SUF system protein SufT, putative SmaCSM2_RS03750 4d6388360d2e6a991dc91b40de1e3f1f 183 Gene3D G3DSA:3.30.300.130 79 182 3.5E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SmaCSM2_RS03750 4d6388360d2e6a991dc91b40de1e3f1f 183 Pfam PF01883 Iron-sulfur cluster assembly protein 84 159 4.7E-13 T 28-03-2018 IPR002744 MIP18 family-like SmaCSM2_RS03750 4d6388360d2e6a991dc91b40de1e3f1f 183 SUPERFAMILY SSF117916 80 181 7.52E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 Gene3D G3DSA:2.102.10.10 39 205 5.2E-36 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 Pfam PF00355 Rieske [2Fe-2S] domain 61 185 4.3E-10 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 6.3E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 158 170 6.3E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 171 183 6.3E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 Gene3D G3DSA:1.20.5.510 8 38 4.4E-16 T 28-03-2018 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 7 44 1.5E-15 T 28-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 13 199 1.3E-66 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 SmaCSM2_RS07135 3721426621e38749ecc8e0efb8fba795 206 SUPERFAMILY SSF50022 34 198 2.62E-37 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 183 1.1E-5 T 28-03-2018 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 Gene3D G3DSA:3.40.50.720 43 246 1.8E-64 T 28-03-2018 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 Gene3D G3DSA:3.40.50.720 1 42 1.0E-10 T 28-03-2018 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 6.9E-60 T 28-03-2018 SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 SUPERFAMILY SSF51735 4 244 4.68E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.4E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS14735 352abf7a3b6ee65fae4ff79d31a256a5 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 3.2E-118 T 28-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 SmaCSM2_RS06890 654599c47f1bc4cca9da88dc55348954 322 SUPERFAMILY SSF161098 32 309 2.06E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS06890 654599c47f1bc4cca9da88dc55348954 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 310 9.1E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS06890 654599c47f1bc4cca9da88dc55348954 322 Gene3D G3DSA:1.10.3720.10 14 310 1.2E-33 T 28-03-2018 SmaCSM2_RS06890 654599c47f1bc4cca9da88dc55348954 322 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 22 315 3.3E-91 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SmaCSM2_RS04830 ac95320e9c0ba0f6b3962ebc71a64da2 318 Gene3D G3DSA:1.10.8.10 169 209 5.3E-4 T 28-03-2018 SmaCSM2_RS04830 ac95320e9c0ba0f6b3962ebc71a64da2 318 Pfam PF13177 DNA polymerase III, delta subunit 8 168 1.1E-33 T 28-03-2018 SmaCSM2_RS04830 ac95320e9c0ba0f6b3962ebc71a64da2 318 Gene3D G3DSA:3.40.50.300 6 168 2.4E-24 T 28-03-2018 SmaCSM2_RS04830 ac95320e9c0ba0f6b3962ebc71a64da2 318 SUPERFAMILY SSF52540 6 208 1.65E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10420 988e60160aebf8e07f5c63f1174687e7 246 SUPERFAMILY SSF55729 10 232 8.47E-88 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS10420 988e60160aebf8e07f5c63f1174687e7 246 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 246 95.586 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 SmaCSM2_RS10420 988e60160aebf8e07f5c63f1174687e7 246 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 36 222 1.8E-59 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 SmaCSM2_RS10420 988e60160aebf8e07f5c63f1174687e7 246 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 39 209 1.3E-69 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 247 2.8E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 254 2.1E-82 T 28-03-2018 SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 SUPERFAMILY SSF56219 1 254 8.24E-77 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 Gene3D G3DSA:3.60.10.10 1 255 7.5E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 211 222 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 SmaCSM2_RS21365 1f528e89c171829bb7e5470ddf7648cd 255 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 254 1.1E-75 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SmaCSM2_RS20180 9661782148d893fef55e13df10c7d289 492 Pfam PF00916 Sulfate permease family 16 145 4.0E-27 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SmaCSM2_RS20180 9661782148d893fef55e13df10c7d289 492 Pfam PF00916 Sulfate permease family 165 347 9.4E-30 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SmaCSM2_RS20180 9661782148d893fef55e13df10c7d289 492 Gene3D G3DSA:3.30.750.24 391 481 2.6E-13 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS20180 9661782148d893fef55e13df10c7d289 492 SUPERFAMILY SSF52091 396 482 5.1E-11 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS20180 9661782148d893fef55e13df10c7d289 492 Pfam PF01740 STAS domain 401 480 6.9E-7 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 SUPERFAMILY SSF52172 1 130 2.28E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 Pfam PF00072 Response regulator receiver domain 5 115 2.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 SMART SM00448 2 115 3.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 4.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 SMART SM00421 149 206 2.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 Gene3D G3DSA:3.40.50.2300 2 125 9.6E-29 T 28-03-2018 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 SUPERFAMILY SSF46894 143 213 7.14E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11440 af0178968d0b817b7fc8a571ffd7f691 224 Gene3D G3DSA:1.10.10.10 126 216 2.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 Pfam PF01022 Bacterial regulatory protein, arsR family 18 61 9.6E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 SMART SM00418 10 88 4.9E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 SUPERFAMILY SSF46785 5 92 2.23E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.1E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 1.1E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.1E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS20080 f126a006125474d7570240b024bac497 97 Gene3D G3DSA:1.10.10.10 1 96 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 SMART SM00387 353 460 1.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 Pfam PF08521 Two-component sensor kinase N-terminal 20 163 5.8E-31 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 SUPERFAMILY SSF55874 295 457 1.57E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 SMART SM00388 241 306 1.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 304 2.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 Gene3D G3DSA:1.10.287.130 231 302 1.3E-11 T 28-03-2018 SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 Gene3D G3DSA:3.30.565.10 311 460 1.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 453 3.9E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11965 6271b0babfdc7d0712ba9b976cb175bb 460 SUPERFAMILY SSF47384 225 305 1.02E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 Pfam PF08281 Sigma-70, region 4 134 186 2.2E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 Gene3D G3DSA:1.10.10.10 113 193 7.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 Gene3D G3DSA:1.10.1740.10 18 100 1.7E-9 T 28-03-2018 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 SUPERFAMILY SSF88659 104 190 1.2E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 190 1.9E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 Pfam PF04542 Sigma-70 region 2 34 97 1.3E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS03730 a5f2cc2a18e081fd1f8fb7caf6236108 194 SUPERFAMILY SSF88946 29 102 2.63E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02110 0ef5948065170f87ff2ba2870b03964b 381 SUPERFAMILY SSF50974 98 362 1.23E-35 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SmaCSM2_RS02110 0ef5948065170f87ff2ba2870b03964b 381 SUPERFAMILY SSF50974 6 133 3.4E-8 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SmaCSM2_RS02110 0ef5948065170f87ff2ba2870b03964b 381 Gene3D G3DSA:2.130.10.10 27 158 4.0E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS02110 0ef5948065170f87ff2ba2870b03964b 381 Gene3D G3DSA:2.130.10.10 277 379 1.0E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS02110 0ef5948065170f87ff2ba2870b03964b 381 Gene3D G3DSA:2.130.10.10 159 276 2.7E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS19365 c062c120ddc6949ba4c63a40a89207ac 331 Pfam PF01148 Cytidylyltransferase family 58 323 2.4E-64 T 28-03-2018 SmaCSM2_RS19235 912bc9bdd501834e46632ad586dc1fc0 112 SUPERFAMILY SSF54913 5 108 1.96E-36 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SmaCSM2_RS19235 912bc9bdd501834e46632ad586dc1fc0 112 Pfam PF03091 CutA1 divalent ion tolerance protein 9 105 4.1E-34 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SmaCSM2_RS19235 912bc9bdd501834e46632ad586dc1fc0 112 Gene3D G3DSA:3.30.70.120 5 111 2.2E-36 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 SUPERFAMILY SSF51735 6 254 1.94E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 Gene3D G3DSA:3.40.50.720 4 256 5.6E-60 T 28-03-2018 SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 4.9E-53 T 28-03-2018 SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20005 8d8d5e559168aa471e1481077d3ca6bd 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 257 1.2E-19 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 Gene3D G3DSA:3.60.10.10 1 266 3.9E-53 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 262 5.7E-66 T 28-03-2018 SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 SUPERFAMILY SSF56219 1 266 2.75E-75 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS01670 be6bdfdca4e2a15f6091a4e2a39e41a0 266 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 264 1.8E-70 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SmaCSM2_RS05930 4646753e27c53b8e0b212a460c161df4 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 4.9E-100 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SmaCSM2_RS05930 4646753e27c53b8e0b212a460c161df4 316 Gene3D G3DSA:3.40.50.1220 10 300 3.5E-5 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS05930 4646753e27c53b8e0b212a460c161df4 316 Pfam PF02401 LytB protein 3 284 7.1E-93 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SmaCSM2_RS05930 4646753e27c53b8e0b212a460c161df4 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 38.646 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SmaCSM2_RS07060 c814fb3aa7fab2086ca0347fd02ed3f3 454 Gene3D G3DSA:3.40.309.10 247 437 3.9E-64 T 28-03-2018 SmaCSM2_RS07060 c814fb3aa7fab2086ca0347fd02ed3f3 454 Pfam PF00171 Aldehyde dehydrogenase family 2 451 2.4E-136 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS07060 c814fb3aa7fab2086ca0347fd02ed3f3 454 SUPERFAMILY SSF53720 2 453 1.83E-138 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS07060 c814fb3aa7fab2086ca0347fd02ed3f3 454 Gene3D G3DSA:3.40.605.10 1 246 9.2E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS07060 c814fb3aa7fab2086ca0347fd02ed3f3 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 255 266 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 Gene3D G3DSA:3.40.630.30 308 472 3.5E-23 T 28-03-2018 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 SMART SM00563 83 200 3.3E-10 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 SUPERFAMILY SSF69593 75 243 1.83E-10 T 28-03-2018 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 Pfam PF13444 Acetyltransferase (GNAT) domain 326 427 5.4E-23 T 28-03-2018 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 Gene3D G3DSA:3.40.1130.10 54 264 3.8E-25 T 28-03-2018 SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 SUPERFAMILY SSF55729 314 467 3.06E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS03390 b88a2393abb03c2a7c2c4c7c54a38c57 571 Pfam PF01553 Acyltransferase 75 197 1.4E-8 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS15000 87974a777084671bfdc10a50bbfc3ee6 118 SUPERFAMILY SSF46955 17 114 3.02E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS15000 87974a777084671bfdc10a50bbfc3ee6 118 Gene3D G3DSA:1.10.1660.10 14 118 9.5E-26 T 28-03-2018 SmaCSM2_RS15000 87974a777084671bfdc10a50bbfc3ee6 118 SMART SM00422 19 89 9.8E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS15000 87974a777084671bfdc10a50bbfc3ee6 118 Pfam PF13411 MerR HTH family regulatory protein 19 86 6.1E-22 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS16620 17956d10ffd74ef50c87c742730477e1 65 Pfam PF10746 Phage holin T7 family, holin superfamily II 13 61 8.0E-10 T 28-03-2018 IPR019682 Bacteriophage T7, Gp17.5, holin GO:0019076|GO:0019835 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 Gene3D G3DSA:2.20.28.10 18 73 2.6E-23 T 28-03-2018 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 SUPERFAMILY SSF57802 19 73 3.53E-22 T 28-03-2018 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 PRINTS PR00163 Rubredoxin signature 22 38 3.8E-7 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 PRINTS PR00163 Rubredoxin signature 52 68 3.8E-7 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 PIRSF PIRSF000071 19 74 2.8E-24 T 28-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 Pfam PF00301 Rubredoxin 23 68 1.1E-21 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 SmaCSM2_RS17520 f9400d93db36b502e17e31eff0781c4b 74 ProSitePatterns PS00202 Rubredoxin signature. 52 62 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 Pfam PF02261 Aspartate decarboxylase 1 114 4.5E-49 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 7.1E-51 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 Gene3D G3DSA:2.40.40.20 1 117 2.3E-51 T 28-03-2018 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 69.173 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 PIRSF PIRSF006246 1 125 8.6E-49 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 SUPERFAMILY SSF50692 1 121 2.73E-47 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS08360 dc35e8c0de0d90c073d3c903d6fc2b5f 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 122 4.0E-53 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 SUPERFAMILY SSF56925 27 187 4.97E-18 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 Gene3D G3DSA:3.30.1330.60 206 363 6.1E-40 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 PRINTS PR01021 OMPA domain signature 254 276 1.6E-18 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 PRINTS PR01021 OMPA domain signature 284 299 1.6E-18 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 PRINTS PR01021 OMPA domain signature 299 315 1.6E-18 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 Pfam PF00691 OmpA family 253 344 2.8E-22 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 SUPERFAMILY SSF103088 251 361 6.54E-36 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 SUPERFAMILY SSF103647 209 248 1.44E-5 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 Gene3D G3DSA:2.40.160.20 8 205 3.3E-26 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 Pfam PF13505 Outer membrane protein beta-barrel domain 8 188 1.6E-19 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel SmaCSM2_RS04215 a8d5c2733a1525c6b2609a0b57dbc124 363 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 87 170 6.9E-4 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 Pfam PF05552 Conserved TM helix 27 63 6.5E-7 T 28-03-2018 IPR008910 Conserved TM helix SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 Pfam PF00924 Mechanosensitive ion channel 71 268 3.1E-48 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 SUPERFAMILY SSF50182 113 179 5.56E-16 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 SUPERFAMILY SSF82689 182 277 7.72E-27 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 Gene3D G3DSA:2.30.30.60 129 179 6.4E-14 T 28-03-2018 SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 Gene3D G3DSA:3.30.70.100 180 273 6.3E-22 T 28-03-2018 SmaCSM2_RS13300 89c8e13f4fcaa80d32dcd05da603771b 297 SUPERFAMILY SSF82861 28 112 6.93E-17 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SmaCSM2_RS10910 c6009cd2c2468e6cf65ab1858e404267 526 Gene3D G3DSA:3.40.50.300 1 348 4.1E-24 T 28-03-2018 SmaCSM2_RS10910 c6009cd2c2468e6cf65ab1858e404267 526 Pfam PF13476 AAA domain 5 54 6.6E-12 T 28-03-2018 SmaCSM2_RS10910 c6009cd2c2468e6cf65ab1858e404267 526 SUPERFAMILY SSF52540 204 348 7.19E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10910 c6009cd2c2468e6cf65ab1858e404267 526 SUPERFAMILY SSF52540 1 141 7.19E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10910 c6009cd2c2468e6cf65ab1858e404267 526 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 259 332 1.4E-10 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 Gene3D G3DSA:3.40.190.10 176 260 6.9E-23 T 28-03-2018 SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 SUPERFAMILY SSF46785 3 112 2.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 Pfam PF03466 LysR substrate binding domain 89 288 3.3E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 SUPERFAMILY SSF53850 89 290 1.81E-44 T 28-03-2018 SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 Gene3D G3DSA:1.10.10.10 2 84 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04960 075ec08a6c411fc7e30b6e9d4217d559 291 Gene3D G3DSA:3.40.190.10 88 175 2.0E-13 T 28-03-2018 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Gene3D G3DSA:1.10.460.10 464 828 2.1E-41 T 28-03-2018 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Pfam PF01751 Toprim domain 5 117 1.2E-26 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 SMART SM00493 3 103 1.2E-31 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 381 397 1.1E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 488 502 1.1E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 303 312 1.1E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.1E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 166 184 1.1E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 683 53.314 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 SUPERFAMILY SSF56712 3 602 9.55E-188 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Gene3D G3DSA:1.10.460.10 139 331 2.1E-47 T 28-03-2018 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Pfam PF01131 DNA topoisomerase 133 562 3.9E-131 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Pfam PF13368 Topoisomerase C-terminal repeat 717 762 1.9E-11 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Pfam PF13368 Topoisomerase C-terminal repeat 657 705 1.7E-14 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Pfam PF13368 Topoisomerase C-terminal repeat 594 656 2.3E-14 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Gene3D G3DSA:2.70.20.10 335 463 2.4E-42 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 616 3.8E-229 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 SMART SM00437 252 525 1.1E-116 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 Gene3D G3DSA:3.40.50.140 2 133 7.7E-41 T 28-03-2018 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 SMART SM00436 108 196 9.5E-45 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SmaCSM2_RS19085 d16a619a3ce2096eea09995f05c45af1 829 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 289 312 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SmaCSM2_RS20695 a320d6f169412d1b66ee6ec2a2f00765 471 Gene3D G3DSA:1.20.1600.10 22 471 9.3E-99 T 28-03-2018 SmaCSM2_RS20695 a320d6f169412d1b66ee6ec2a2f00765 471 SUPERFAMILY SSF56954 2 468 1.7E-106 T 28-03-2018 SmaCSM2_RS20695 a320d6f169412d1b66ee6ec2a2f00765 471 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 467 2.4E-120 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS20695 a320d6f169412d1b66ee6ec2a2f00765 471 Pfam PF02321 Outer membrane efflux protein 65 255 5.8E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS20695 a320d6f169412d1b66ee6ec2a2f00765 471 Pfam PF02321 Outer membrane efflux protein 281 464 5.6E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Gene3D G3DSA:3.40.50.2300 72 212 8.5E-35 T 28-03-2018 SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SMART SM00448 84 197 4.3E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SMART SM00052 377 621 2.0E-10 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Gene3D G3DSA:3.30.70.270 217 384 1.1E-16 T 28-03-2018 SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SUPERFAMILY SSF141868 388 613 8.5E-35 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Gene3D G3DSA:3.20.20.450 385 618 4.9E-41 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SUPERFAMILY SSF52172 82 208 9.68E-36 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Pfam PF00563 EAL domain 388 613 7.2E-35 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SMART SM00267 201 375 4.2E-5 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Pfam PF00072 Response regulator receiver domain 86 197 8.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 SUPERFAMILY SSF55073 225 366 1.1E-12 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS19615 07e75e47b49d780487d4afe725c83a62 629 Pfam PF00990 Diguanylate cyclase, GGDEF domain 224 365 4.0E-8 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS20140 7f75f7f6be077256af334722b97f9cf8 400 Pfam PF02417 Chromate transporter 230 393 3.3E-31 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 SmaCSM2_RS20140 7f75f7f6be077256af334722b97f9cf8 400 Pfam PF02417 Chromate transporter 13 178 6.0E-34 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 SmaCSM2_RS20140 7f75f7f6be077256af334722b97f9cf8 400 PIRSF PIRSF004810 2 399 4.2E-122 T 28-03-2018 IPR014047 Chromate transporter, long chain SmaCSM2_RS20140 7f75f7f6be077256af334722b97f9cf8 400 TIGRFAM TIGR00937 2A51: chromate efflux transporter 19 393 3.0E-99 T 28-03-2018 IPR014047 Chromate transporter, long chain SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Gene3D G3DSA:3.40.50.300 203 665 5.8E-36 T 28-03-2018 SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 SUPERFAMILY SSF52540 212 347 9.21E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 SUPERFAMILY SSF52540 557 861 9.21E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Pfam PF13361 UvrD-like helicase C-terminal domain 776 845 2.2E-15 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Gene3D G3DSA:3.30.65.10 863 912 1.2E-4 T 28-03-2018 SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Gene3D G3DSA:3.40.50.300 666 862 1.7E-25 T 28-03-2018 SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Pfam PF13245 AAA domain 217 646 5.9E-22 T 28-03-2018 SmaCSM2_RS13580 e55bb2123db8316f8e63557ad7be2ccc 916 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 1 165 1.6E-31 T 28-03-2018 IPR022161 DNA helicase IV, N-terminal domain SmaCSM2_RS19410 3aeba22d92f6ae89adaf533247058660 110 Pfam PF01381 Helix-turn-helix 55 98 4.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS19410 3aeba22d92f6ae89adaf533247058660 110 SMART SM00530 54 108 0.0092 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS19410 3aeba22d92f6ae89adaf533247058660 110 SUPERFAMILY SSF47413 54 100 8.7E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS19410 3aeba22d92f6ae89adaf533247058660 110 Gene3D G3DSA:1.10.260.40 44 102 1.9E-9 T 28-03-2018 SmaCSM2_RS01120 311a9a6387e34466134ceb63e547e61e 268 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 1 265 61.4 T 28-03-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 SmaCSM2_RS01120 311a9a6387e34466134ceb63e547e61e 268 Gene3D G3DSA:3.40.50.1220 4 267 6.3E-69 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS01120 311a9a6387e34466134ceb63e547e61e 268 Pfam PF02146 Sir2 family 20 221 2.9E-47 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 SmaCSM2_RS01120 311a9a6387e34466134ceb63e547e61e 268 SUPERFAMILY SSF52467 5 264 3.27E-80 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS07645 b584677fd2805208d4a38d28152b87b9 199 TIGRFAM TIGR03748 conj_PilL: integrating conjugative element protein PilL, PFGI-1 class 61 164 2.3E-42 T 28-03-2018 IPR022260 Integrating conjugative element protein PilL, PFGI-1 SmaCSM2_RS08150 8be61fff1a0f10d90ccce99f7f8fb768 163 Pfam PF02631 RecX family 42 158 5.4E-28 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SmaCSM2_RS08150 8be61fff1a0f10d90ccce99f7f8fb768 163 Gene3D G3DSA:1.10.10.10 18 65 5.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08150 8be61fff1a0f10d90ccce99f7f8fb768 163 Hamap MF_01114 Regulatory protein RecX [recX]. 10 163 13.892 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SmaCSM2_RS08150 8be61fff1a0f10d90ccce99f7f8fb768 163 Gene3D G3DSA:1.10.10.10 112 163 3.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08150 8be61fff1a0f10d90ccce99f7f8fb768 163 Gene3D G3DSA:1.10.10.10 66 110 7.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15175 213e11c0213da245a5e39ab1f4faceaf 118 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 117 3.7E-36 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15175 213e11c0213da245a5e39ab1f4faceaf 118 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 118 19.15 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SmaCSM2_RS08530 077477a464e70683b4a027bf5748ee3c 295 SMART SM00849 42 263 1.0E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS08530 077477a464e70683b4a027bf5748ee3c 295 Gene3D G3DSA:3.60.15.10 1 275 4.2E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS08530 077477a464e70683b4a027bf5748ee3c 295 SUPERFAMILY SSF56281 1 271 7.08E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS08530 077477a464e70683b4a027bf5748ee3c 295 Pfam PF00753 Metallo-beta-lactamase superfamily 52 263 2.0E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.169 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 Gene3D G3DSA:3.90.226.10 32 312 4.6E-65 T 28-03-2018 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 316 6.5E-153 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 7.5E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 3.3E-64 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS06565 4e7e7109f0bdb56ae7557c6ff1a8423f 319 SUPERFAMILY SSF52096 5 316 7.76E-100 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 388 38.764 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 308 333 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 341 352 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.6E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 PIRSF PIRSF000724 1 391 7.9E-133 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 Gene3D G3DSA:3.40.50.1260 3 174 3.2E-58 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 Pfam PF00162 Phosphoglycerate kinase 6 378 1.0E-141 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 Gene3D G3DSA:3.40.50.1260 175 376 3.6E-79 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS17160 d6bf394867458ee0bef8523ae3c118ee 391 SUPERFAMILY SSF53748 3 387 1.77E-144 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 SUPERFAMILY SSF52540 141 382 2.32E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 SUPERFAMILY SSF46689 354 456 2.24E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Gene3D G3DSA:1.10.10.60 371 457 3.4E-16 T 28-03-2018 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 SMART SM00382 160 303 1.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Pfam PF02954 Bacterial regulatory protein, Fis family 414 454 2.9E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Gene3D G3DSA:1.10.8.60 313 370 3.0E-22 T 28-03-2018 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 SMART SM00448 5 116 1.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Gene3D G3DSA:3.40.50.2300 1 145 1.1E-35 T 28-03-2018 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 2.2E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 2.2E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Pfam PF00158 Sigma-54 interaction domain 141 306 2.7E-65 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Pfam PF00072 Response regulator receiver domain 8 115 8.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 Gene3D G3DSA:3.40.50.300 146 312 3.5E-25 T 28-03-2018 SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 SUPERFAMILY SSF52172 6 183 2.56E-42 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16915 789b604d3c999413e442cd59d89ec022 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS14880 49bf92c7350b33d5209323b22f1a217a 185 Pfam PF11218 Protein of unknown function (DUF3011) 44 182 1.2E-35 T 28-03-2018 IPR021381 Protein of unknown function DUF3011 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 SMART SM01060 46 430 3.3E-274 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 122 140 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 162 180 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 143 160 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 359 385 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 59 82 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PRINTS PR00067 Catalase signature 327 354 1.3E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 PIRSF PIRSF038928 31 521 5.0E-216 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 SUPERFAMILY SSF56634 26 521 2.75E-205 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 Gene3D G3DSA:2.40.180.10 16 396 1.1E-154 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 Pfam PF06628 Catalase-related immune-responsive 453 515 7.2E-22 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 Pfam PF00199 Catalase 46 427 2.3E-181 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS06120 08768a6ce5b8a4f3311f064dc4f54d34 547 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 372 380 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SmaCSM2_RS13085 f0d5006d446938accf4b59296bdddc7c 280 Gene3D G3DSA:3.40.30.10 136 274 7.5E-20 T 28-03-2018 SmaCSM2_RS13085 f0d5006d446938accf4b59296bdddc7c 280 SUPERFAMILY SSF52833 120 276 2.76E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS13085 f0d5006d446938accf4b59296bdddc7c 280 SUPERFAMILY SSF54423 51 109 4.71E-14 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal SmaCSM2_RS13085 f0d5006d446938accf4b59296bdddc7c 280 Gene3D G3DSA:3.10.450.70 55 118 7.6E-18 T 28-03-2018 SmaCSM2_RS13085 f0d5006d446938accf4b59296bdddc7c 280 Pfam PF13098 Thioredoxin-like domain 146 272 5.8E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 188 6.1E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 Pfam PF04542 Sigma-70 region 2 36 103 9.8E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 Pfam PF08281 Sigma-70, region 4 133 181 1.4E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 SUPERFAMILY SSF88659 132 189 1.21E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 Gene3D G3DSA:1.10.10.10 138 189 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 Gene3D G3DSA:1.10.1740.10 10 137 7.2E-24 T 28-03-2018 SmaCSM2_RS15785 d67e9d20491f6f1703458fa48ee49fe5 192 SUPERFAMILY SSF88946 13 110 1.57E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 Gene3D G3DSA:3.60.120.10 2 454 5.4E-141 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 Pfam PF00425 chorismate binding enzyme 189 442 3.6E-95 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 SUPERFAMILY SSF56322 16 451 1.23E-123 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 99 446 2.9E-128 T 28-03-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 PRINTS PR00095 Anthranilate synthase component I signature 290 303 3.9E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 PRINTS PR00095 Anthranilate synthase component I signature 384 398 3.9E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 PRINTS PR00095 Anthranilate synthase component I signature 399 413 3.9E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 PRINTS PR00095 Anthranilate synthase component I signature 304 317 3.9E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS04815 720a4611c2d402b6915825362d484b16 454 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 146 6.2E-7 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 10 319 49.596 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Gene3D G3DSA:3.30.70.20 204 305 4.9E-11 T 28-03-2018 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 SUPERFAMILY SSF54862 174 324 1.51E-20 T 28-03-2018 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Gene3D G3DSA:1.25.40.70 306 354 1.2E-4 T 28-03-2018 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Gene3D G3DSA:3.30.70.20 65 203 2.5E-4 T 28-03-2018 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Pfam PF08331 Domain of unknown function (DUF1730) 65 144 9.3E-24 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 Pfam PF13484 4Fe-4S double cluster binding domain 196 260 1.4E-21 T 28-03-2018 SmaCSM2_RS14775 95f0bf5615d80e8dd56bcea5b54bbee4 356 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 17 353 1.5E-150 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Pfam PF07676 WD40-like Beta Propeller Repeat 208 232 1.6E-6 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Pfam PF07676 WD40-like Beta Propeller Repeat 284 319 1.4E-12 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Pfam PF07676 WD40-like Beta Propeller Repeat 242 276 6.5E-9 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Pfam PF04052 TolB amino-terminal domain 27 131 3.1E-28 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 20 433 1.8E-157 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:2.140.10.30 382 437 2.1E-4 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:2.60.120.20 283 329 3.2E-12 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:2.60.120.20 330 381 2.1E-4 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:2.60.120.20 168 240 6.0E-12 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:2.60.120.20 241 282 1.9E-8 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Hamap MF_00671 Protein TolB [tolB]. 8 432 36.154 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 SUPERFAMILY SSF69304 157 434 1.06E-55 T 28-03-2018 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 SUPERFAMILY SSF52964 33 164 7.98E-35 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 SmaCSM2_RS16675 1c579ff724fe4df28c523cd3bb502367 439 Gene3D G3DSA:3.40.50.10070 26 167 6.6E-31 T 28-03-2018 SmaCSM2_RS05890 53d5e5ad25c45a84e7e0374a7bbb55d5 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.8E-33 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05890 53d5e5ad25c45a84e7e0374a7bbb55d5 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-36 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05890 53d5e5ad25c45a84e7e0374a7bbb55d5 102 SUPERFAMILY SSF141091 1 100 1.96E-33 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05890 53d5e5ad25c45a84e7e0374a7bbb55d5 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05890 53d5e5ad25c45a84e7e0374a7bbb55d5 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 25.112 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 Gene3D G3DSA:3.40.605.10 3 247 1.0E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 PIRSF PIRSF000151 4 423 5.5E-168 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 SUPERFAMILY SSF53720 9 422 4.58E-112 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 Pfam PF00171 Aldehyde dehydrogenase family 10 287 1.5E-15 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 Gene3D G3DSA:3.40.605.10 248 423 7.6E-35 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 11 422 40.901 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS14585 a783fb86fe971ed8f5f523b384364050 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 410 1.6E-139 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SmaCSM2_RS08230 28d30b8a8e669f8dedad977c3d4f3966 379 SUPERFAMILY SSF103473 15 376 5.49E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS08230 28d30b8a8e669f8dedad977c3d4f3966 379 Gene3D G3DSA:1.20.1250.20 14 191 3.4E-16 T 28-03-2018 SmaCSM2_RS08230 28d30b8a8e669f8dedad977c3d4f3966 379 Pfam PF07690 Major Facilitator Superfamily 16 231 1.2E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS08230 28d30b8a8e669f8dedad977c3d4f3966 379 Gene3D G3DSA:1.20.1250.20 192 378 3.3E-16 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 42 718 1.2E-224 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SUPERFAMILY SSF81271 391 463 1.35E-17 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Pfam PF13328 HD domain 42 191 3.2E-51 T 28-03-2018 IPR003607 HD/PDEase domain SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SUPERFAMILY SSF109604 22 206 4.55E-71 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Gene3D G3DSA:3.30.460.10 210 341 1.2E-36 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SUPERFAMILY SSF81301 197 408 7.19E-57 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Gene3D G3DSA:3.10.20.30 398 473 5.7E-19 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SUPERFAMILY SSF55021 648 719 1.57E-6 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Pfam PF04607 Region found in RelA / SpoT proteins 251 360 3.9E-32 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Pfam PF13291 ACT domain 643 719 2.3E-15 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Gene3D G3DSA:3.30.70.260 642 720 4.2E-10 T 28-03-2018 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SMART SM00954 251 361 6.5E-58 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 SMART SM00471 57 169 4.8E-13 T 28-03-2018 IPR003607 HD/PDEase domain SmaCSM2_RS17370 e826df287f9d2da42b6dc81c1196532c 720 Pfam PF02824 TGS domain 404 463 1.9E-15 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 SMART SM00671 82 117 1.9E-4 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 SMART SM00671 118 153 0.0019 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 Gene3D G3DSA:2.60.40.1180 59 164 1.1E-18 T 28-03-2018 SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 Pfam PF08238 Sel1 repeat 84 117 4.8E-6 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 Pfam PF08238 Sel1 repeat 118 153 0.0027 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS09160 082a54e57e6182b21db3c7572c3cf001 169 SUPERFAMILY SSF81901 29 158 3.79E-19 T 28-03-2018 SmaCSM2_RS16315 4f603177cd8e93b8839f6f1b250ba5c5 343 Pfam PF00561 alpha/beta hydrolase fold 59 324 9.9E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS16315 4f603177cd8e93b8839f6f1b250ba5c5 343 Gene3D G3DSA:3.40.50.1820 23 339 3.6E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16315 4f603177cd8e93b8839f6f1b250ba5c5 343 SUPERFAMILY SSF53474 44 334 2.92E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16315 4f603177cd8e93b8839f6f1b250ba5c5 343 PIRSF PIRSF000443 20 343 6.5E-63 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SmaCSM2_RS12985 d6cf73f2ed8b1376ac4b3a37e29beb70 335 SUPERFAMILY SSF102198 67 331 4.97E-43 T 28-03-2018 SmaCSM2_RS12985 d6cf73f2ed8b1376ac4b3a37e29beb70 335 Gene3D G3DSA:3.50.30.50 65 333 1.5E-55 T 28-03-2018 SmaCSM2_RS12985 d6cf73f2ed8b1376ac4b3a37e29beb70 335 Pfam PF04199 Putative cyclase 70 267 8.7E-31 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 SmaCSM2_RS16605 f62e7f54f2e33abdca20e5a5e2f8efbd 287 SUPERFAMILY SSF53474 34 279 9.32E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16605 f62e7f54f2e33abdca20e5a5e2f8efbd 287 Gene3D G3DSA:3.40.50.1820 34 282 1.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16605 f62e7f54f2e33abdca20e5a5e2f8efbd 287 Pfam PF00756 Putative esterase 49 207 1.2E-21 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SmaCSM2_RS02525 c7b4159aa02be31d51b088db7538be6c 120 Gene3D G3DSA:1.10.150.20 4 79 8.4E-20 T 28-03-2018 SmaCSM2_RS02525 c7b4159aa02be31d51b088db7538be6c 120 Pfam PF04994 TfoX C-terminal domain 5 77 3.0E-24 T 28-03-2018 IPR007077 TfoX, C-terminal SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 Hamap MF_01971 Kynurenine 3-monooxygenase [kmo]. 6 445 26.702 T 28-03-2018 IPR027545 Kynurenine 3-monooxygenase GO:0004502|GO:0006569|GO:0019805 KEGG: 00380+1.14.13.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7765|Reactome: R-HSA-71240 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 Pfam PF01494 FAD binding domain 11 358 3.7E-28 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 SUPERFAMILY SSF51905 11 179 2.78E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 SUPERFAMILY SSF51905 283 390 2.78E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 Gene3D G3DSA:3.50.50.60 9 364 1.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 1.1E-18 T 28-03-2018 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 1.1E-18 T 28-03-2018 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-18 T 28-03-2018 SmaCSM2_RS13950 3e7f1673dc1aa7d20ed00150e6f92ab0 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 1.1E-18 T 28-03-2018 SmaCSM2_RS18025 8d5a31a510481c54a4517e1740fc44cb 481 Gene3D G3DSA:3.30.70.270 296 466 1.6E-53 T 28-03-2018 SmaCSM2_RS18025 8d5a31a510481c54a4517e1740fc44cb 481 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 302 464 1.7E-49 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS18025 8d5a31a510481c54a4517e1740fc44cb 481 SUPERFAMILY SSF55073 311 464 1.1E-45 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS18025 8d5a31a510481c54a4517e1740fc44cb 481 SMART SM00267 295 465 2.3E-65 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS18025 8d5a31a510481c54a4517e1740fc44cb 481 Pfam PF00990 Diguanylate cyclase, GGDEF domain 307 461 7.6E-44 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 Gene3D G3DSA:1.10.260.40 2 54 1.6E-21 T 28-03-2018 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.9E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 Pfam PF13377 Periplasmic binding protein-like domain 171 329 1.1E-38 T 28-03-2018 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 Gene3D G3DSA:3.40.50.2300 55 176 4.8E-36 T 28-03-2018 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 SMART SM00354 1 71 5.6E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 SUPERFAMILY SSF47413 1 59 1.69E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 Gene3D G3DSA:3.40.50.2300 177 313 3.7E-46 T 28-03-2018 SmaCSM2_RS05520 2fa64bd9b585f09c6e6a164918759947 335 SUPERFAMILY SSF53822 62 332 2.19E-75 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 434 443 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Pfam PF00158 Sigma-54 interaction domain 226 391 1.9E-61 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 SUPERFAMILY SSF52540 225 461 1.1E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 311 326 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:3.40.50.2300 6 103 1.2E-18 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:1.10.10.60 467 527 9.7E-8 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:1.10.8.60 398 466 5.1E-14 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 SMART SM00382 245 388 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:1.20.5.170 184 222 2.8E-5 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:3.40.50.300 223 396 1.1E-23 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Gene3D G3DSA:3.40.50.10660 104 183 2.2E-23 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 SUPERFAMILY SSF159800 18 200 4.18E-50 T 28-03-2018 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 SUPERFAMILY SSF46689 434 524 4.78E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 249 262 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 17 524 1.5E-214 T 28-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 SmaCSM2_RS16210 3030dbf24f07e886d5d4caac1c990de7 527 Pfam PF06506 Propionate catabolism activator 41 202 4.4E-48 T 28-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 SUPERFAMILY SSF160113 354 405 9.29E-11 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Pfam PF07411 Domain of unknown function (DUF1508) 362 402 8.1E-5 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Gene3D G3DSA:3.40.50.620 1 211 3.5E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Gene3D G3DSA:1.10.240.10 212 299 2.5E-23 T 28-03-2018 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 332 8.9E-87 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 333 35.732 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 2.4E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 2.4E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 2.4E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 2.4E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Gene3D G3DSA:3.30.160.160 356 399 5.1E-4 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 Pfam PF00579 tRNA synthetases class I (W and Y) 3 285 3.8E-57 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 SUPERFAMILY SSF52374 4 332 9.15E-76 T 28-03-2018 SmaCSM2_RS01400 6b97dea541dab4734fc5b574724ce474 430 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.046 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 SUPERFAMILY SSF54999 5 102 2.62E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 2.5E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.7E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.7E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.7E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 7.0E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 Gene3D G3DSA:3.30.70.600 4 103 1.7E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SmaCSM2_RS03985 88bc7ba949b6285ed9df192d3e73e89c 103 SMART SM01403 7 101 3.0E-56 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SmaCSM2_RS01220 a7a95d8daa12b0ff2f255e621163d9c3 116 Gene3D G3DSA:2.40.10.180 13 115 7.7E-4 T 28-03-2018 SmaCSM2_RS01220 a7a95d8daa12b0ff2f255e621163d9c3 116 Pfam PF05521 Phage head-tail joining protein 7 107 4.9E-11 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 Pfam PF01649 Ribosomal protein S20 2 84 1.1E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 SUPERFAMILY SSF46992 3 86 2.62E-29 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.074 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 Gene3D G3DSA:1.20.58.110 1 89 8.1E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 89 8.0E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05905 18556471863198279d0dba1384d61d3a 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 3.5E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS01775 5a6a811dde4fa20854aecd21197896e1 158 Pfam PF10003 Integral membrane protein (DUF2244) 17 147 3.4E-32 T 28-03-2018 IPR019253 Protein of unknown function DUF2244, transmembrane SmaCSM2_RS03710 eac9db75b6e0a4f965c9e731287c8875 773 Pfam PF07793 Protein of unknown function (DUF1631) 10 765 6.1E-209 T 28-03-2018 IPR012434 Protein of unknown function DUF1631 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 304 354 1.5E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 SUPERFAMILY SSF50447 783 879 1.85E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 879 16.683 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 SUPERFAMILY SSF46955 4 52 1.04E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 SUPERFAMILY SSF52540 378 544 1.49E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:2.40.30.10 782 880 1.1E-27 T 28-03-2018 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Pfam PF00009 Elongation factor Tu GTP binding domain 385 540 7.6E-34 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 ProSitePatterns PS01176 Initiation factor 2 signature. 832 854 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 SUPERFAMILY SSF50447 554 636 1.35E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:2.40.30.10 553 680 1.4E-28 T 28-03-2018 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 383 538 2.8E-31 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 298 881 1.1E-244 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:3.40.50.10050 681 760 5.4E-25 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Pfam PF11987 Translation-initiation factor 2 669 771 2.5E-33 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:3.30.56.50 5 47 9.2E-5 T 28-03-2018 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:3.30.56.50 306 347 1.5E-9 T 28-03-2018 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Gene3D G3DSA:3.40.50.300 375 551 1.4E-40 T 28-03-2018 SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 70 105 3.3E-9 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial SmaCSM2_RS15085 725d9c0b51a4a958d017bb4143379ea3 881 SUPERFAMILY SSF52156 665 788 1.83E-32 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 Gene3D G3DSA:2.40.50.100 33 88 1.4E-4 T 28-03-2018 SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 Pfam PF00529 HlyD membrane-fusion protein of T1SS 267 355 2.6E-6 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 370 2.3E-101 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 Gene3D G3DSA:1.20.1600.10 89 292 1.1E-28 T 28-03-2018 SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 288 2.3E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS18440 1d40e7285843b2e02c409d6b828948a4 394 SUPERFAMILY SSF111369 48 293 1.57E-79 T 28-03-2018 SmaCSM2_RS16385 4f81a87f268108d8bc076bcfedb41a6e 155 Gene3D G3DSA:3.10.129.10 7 151 1.7E-20 T 28-03-2018 SmaCSM2_RS16385 4f81a87f268108d8bc076bcfedb41a6e 155 Pfam PF14539 Domain of unknown function (DUF4442) 18 151 4.1E-54 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 SmaCSM2_RS16385 4f81a87f268108d8bc076bcfedb41a6e 155 SUPERFAMILY SSF54637 8 151 1.37E-21 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 83 326 2.4E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 SUPERFAMILY SSF111369 223 295 4.45E-10 T 28-03-2018 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 Gene3D G3DSA:2.40.50.100 83 149 1.5E-15 T 28-03-2018 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 Gene3D G3DSA:1.20.1600.10 218 364 2.7E-16 T 28-03-2018 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 366 381 2.4E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 95 115 2.4E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 Gene3D G3DSA:1.10.287.470 150 212 6.3E-8 T 28-03-2018 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 SUPERFAMILY SSF111369 87 160 3.01E-11 T 28-03-2018 SmaCSM2_RS06370 0cd793ba8a17a59536c03d166b9f99ce 384 SUPERFAMILY SSF111369 154 212 6.15E-5 T 28-03-2018 SmaCSM2_RS01600 e1a5e9edd2701fc46b3cc2c03e7289d1 234 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site SmaCSM2_RS01600 e1a5e9edd2701fc46b3cc2c03e7289d1 234 Gene3D G3DSA:3.40.140.10 101 225 1.1E-47 T 28-03-2018 SmaCSM2_RS01600 e1a5e9edd2701fc46b3cc2c03e7289d1 234 Pfam PF04002 RadC-like JAB domain 105 224 4.2E-44 T 28-03-2018 IPR025657 RadC-like JAB domain SmaCSM2_RS01600 e1a5e9edd2701fc46b3cc2c03e7289d1 234 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 225 3.1E-66 T 28-03-2018 IPR001405 RadC protein SmaCSM2_RS01600 e1a5e9edd2701fc46b3cc2c03e7289d1 234 Gene3D G3DSA:1.10.150.20 42 87 9.7E-4 T 28-03-2018 SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 TIGRFAM TIGR00576 dut: dUTP diphosphatase 18 155 5.3E-46 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 Gene3D G3DSA:2.70.40.10 119 156 5.7E-15 T 28-03-2018 SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 SUPERFAMILY SSF51283 11 156 1.7E-50 T 28-03-2018 IPR029054 dUTPase-like SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 Pfam PF00692 dUTPase 22 155 3.2E-36 T 28-03-2018 IPR029054 dUTPase-like SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 Gene3D G3DSA:2.70.40.10 1 118 2.1E-38 T 28-03-2018 SmaCSM2_RS01615 ee20ad56a4a080c67e9679212c838414 157 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 12 156 33.002 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 29 470 1.8E-149 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 21 522 1.2E-208 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 292 307 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 429 450 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 246 267 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 351 369 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 67 90 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 137 149 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 398 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 195 214 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 184 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 316 337 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 94 118 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 20 45 9.0E-124 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 Gene3D G3DSA:1.20.210.10 16 526 3.8E-220 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 SUPERFAMILY SSF81442 18 523 4.45E-190 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01785 0af6d97ee6d06f794bba00c0051ea337 535 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 248 302 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01170 4072c16bc4f95fe4531c2d3bf9dae34b 317 Pfam PF06267 Family of unknown function (DUF1028) 22 218 1.9E-54 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 SmaCSM2_RS01170 4072c16bc4f95fe4531c2d3bf9dae34b 317 Gene3D G3DSA:3.60.20.10 19 231 3.5E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS01170 4072c16bc4f95fe4531c2d3bf9dae34b 317 Gene3D G3DSA:1.25.40.10 232 305 8.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS01170 4072c16bc4f95fe4531c2d3bf9dae34b 317 SUPERFAMILY SSF56235 22 227 2.08E-49 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Pfam PF00501 AMP-binding enzyme 81 521 7.2E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 SUPERFAMILY SSF56801 13 638 3.79E-187 T 28-03-2018 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 1 644 52.541 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 19 641 0.0 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Pfam PF13193 AMP-binding enzyme C-terminal domain 530 608 2.6E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Gene3D G3DSA:2.30.38.10 428 514 1.4E-10 T 28-03-2018 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 ProSitePatterns PS00455 Putative AMP-binding domain signature. 260 271 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Gene3D G3DSA:3.30.300.30 517 644 5.0E-28 T 28-03-2018 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Gene3D G3DSA:3.40.50.980 266 427 2.0E-39 T 28-03-2018 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 22 79 4.3E-19 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SmaCSM2_RS21385 2fab69b249d4152c9c4756889228fe26 647 Gene3D G3DSA:3.40.50.980 72 265 2.5E-50 T 28-03-2018 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 SUPERFAMILY SSF46689 213 260 4.93E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 SMART SM00342 176 259 1.8E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 Gene3D G3DSA:2.60.120.10 4 166 2.6E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 Gene3D G3DSA:1.10.10.60 217 261 1.4E-6 T 28-03-2018 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 Gene3D G3DSA:1.10.10.60 167 216 4.4E-11 T 28-03-2018 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 2.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 2.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 Pfam PF02311 AraC-like ligand binding domain 34 133 1.6E-5 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 SUPERFAMILY SSF51182 13 186 3.34E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 214 255 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20870 ce161164ac30ef376a1ff45462f74894 265 Pfam PF12833 Helix-turn-helix domain 183 260 3.2E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS13900 4dd044b3df0aef59478c9117feb074d5 145 TIGRFAM TIGR00166 S6: ribosomal protein bS6 3 94 1.4E-33 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13900 4dd044b3df0aef59478c9117feb074d5 145 SUPERFAMILY SSF54995 1 104 6.93E-36 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13900 4dd044b3df0aef59478c9117feb074d5 145 Gene3D G3DSA:3.30.70.60 1 101 8.6E-31 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SmaCSM2_RS13900 4dd044b3df0aef59478c9117feb074d5 145 Pfam PF01250 Ribosomal protein S6 4 92 3.6E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13900 4dd044b3df0aef59478c9117feb074d5 145 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 2 95 21.529 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 Pfam PF01522 Polysaccharide deacetylase 91 256 8.0E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 Gene3D G3DSA:3.20.20.370 39 598 9.3E-45 T 28-03-2018 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 35 620 1.2E-241 T 28-03-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0042710 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 307 600 2.4E-116 T 28-03-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 SUPERFAMILY SSF51445 381 515 6.84E-6 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 SUPERFAMILY SSF88713 212 258 8.45E-35 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 SUPERFAMILY SSF88713 54 184 8.45E-35 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS14570 0a49623eea1a73d8862eeb9cef6f268c 628 SUPERFAMILY SSF88713 304 314 8.45E-35 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Gene3D G3DSA:2.60.40.1250 22 151 6.2E-40 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Gene3D G3DSA:2.60.40.1250 181 313 3.2E-33 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 ProSitePatterns PS00194 Thioredoxin family active site. 701 719 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 SUPERFAMILY SSF52833 684 783 3.03E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Gene3D G3DSA:3.40.30.10 670 789 1.6E-7 T 28-03-2018 SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 SUPERFAMILY SSF74863 26 141 4.58E-34 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Pfam PF11412 Disulphide bond corrector protein DsbC 189 304 3.8E-31 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Pfam PF11412 Disulphide bond corrector protein DsbC 27 141 1.6E-34 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Pfam PF13899 Thioredoxin-like 689 768 4.7E-15 T 28-03-2018 SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 402 579 6.2E-8 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SmaCSM2_RS19240 864feba505abc8cb5a16c8f57aceab5c 793 SUPERFAMILY SSF74863 189 305 1.44E-30 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain SmaCSM2_RS07125 06fe989367c27578b3ec34c400b8ad80 322 Gene3D G3DSA:1.10.10.10 2 65 5.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07125 06fe989367c27578b3ec34c400b8ad80 322 SUPERFAMILY SSF46785 6 62 4.16E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07125 06fe989367c27578b3ec34c400b8ad80 322 Pfam PF13280 WYL domain 140 310 3.7E-19 T 28-03-2018 IPR026881 WYL domain SmaCSM2_RS07125 06fe989367c27578b3ec34c400b8ad80 322 Pfam PF08279 HTH domain 7 62 5.0E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SmaCSM2_RS14190 4c7bdf8a3c8ef2dedda99145dd9cd77d 180 Pfam PF13302 Acetyltransferase (GNAT) domain 12 147 6.3E-28 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS14190 4c7bdf8a3c8ef2dedda99145dd9cd77d 180 SUPERFAMILY SSF55729 6 150 4.16E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS14190 4c7bdf8a3c8ef2dedda99145dd9cd77d 180 Gene3D G3DSA:3.40.630.30 1 180 2.5E-18 T 28-03-2018 SmaCSM2_RS08160 d7313fed50226171bdb0d4b4d23845b1 67 SUPERFAMILY SSF117130 1 53 1.7E-20 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 SmaCSM2_RS08160 d7313fed50226171bdb0d4b4d23845b1 67 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 4.0E-20 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 SmaCSM2_RS08160 d7313fed50226171bdb0d4b4d23845b1 67 Pfam PF02599 Global regulator protein family 1 52 6.4E-27 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 SmaCSM2_RS08160 d7313fed50226171bdb0d4b4d23845b1 67 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 9.8E-28 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 SmaCSM2_RS08160 d7313fed50226171bdb0d4b4d23845b1 67 Hamap MF_00167 Carbon storage regulator [csrA]. 1 67 21.067 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 SmaCSM2_RS13090 0cc7f6a77f0f44303517305bf3443a86 267 Gene3D G3DSA:3.40.30.10 129 258 7.4E-25 T 28-03-2018 SmaCSM2_RS13090 0cc7f6a77f0f44303517305bf3443a86 267 Pfam PF08534 Redoxin 135 255 8.1E-16 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SmaCSM2_RS13090 0cc7f6a77f0f44303517305bf3443a86 267 SUPERFAMILY SSF52833 104 265 3.41E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS13090 0cc7f6a77f0f44303517305bf3443a86 267 ProSitePatterns PS00194 Thioredoxin family active site. 161 179 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 SUPERFAMILY SSF54631 1 139 9.73E-25 T 28-03-2018 SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 Pfam PF00571 CBS domain 13 60 1.3E-9 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 Pfam PF00571 CBS domain 74 125 9.2E-8 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 Gene3D G3DSA:3.10.580.10 1 138 7.8E-24 T 28-03-2018 SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 SMART SM00116 78 125 0.0011 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS18590 bed8fa942558c7f80f408d98fa98b5ac 143 SMART SM00116 13 60 9.3E-7 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS14265 cc021e0384147ac5b02eea9c6850bb6d 149 SUPERFAMILY SSF69118 15 147 7.33E-42 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS14265 cc021e0384147ac5b02eea9c6850bb6d 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 98 2.1E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS14265 cc021e0384147ac5b02eea9c6850bb6d 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 33 81 1.5E-14 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS14265 cc021e0384147ac5b02eea9c6850bb6d 149 Gene3D G3DSA:1.20.1290.10 5 145 4.4E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS14110 7fce8ff426f86395bf3799a5779f5a18 470 Gene3D G3DSA:2.60.120.650 21 232 2.4E-30 T 28-03-2018 SmaCSM2_RS14110 7fce8ff426f86395bf3799a5779f5a18 470 SMART SM00558 73 241 0.0018 T 28-03-2018 IPR003347 JmjC domain SmaCSM2_RS14110 7fce8ff426f86395bf3799a5779f5a18 470 SUPERFAMILY SSF51197 22 303 1.25E-65 T 28-03-2018 SmaCSM2_RS14110 7fce8ff426f86395bf3799a5779f5a18 470 Pfam PF08007 Cupin superfamily protein 25 337 2.3E-99 T 28-03-2018 IPR003347 JmjC domain SmaCSM2_RS11565 640a3282a6fba89c83a47e4962dbbeb0 432 Gene3D G3DSA:2.40.128.130 31 400 3.5E-10 T 28-03-2018 SmaCSM2_RS11565 640a3282a6fba89c83a47e4962dbbeb0 432 Pfam PF13557 Putative MetA-pathway of phenol degradation 191 377 3.0E-6 T 28-03-2018 IPR025737 MetA-pathway of phenol degradation, putative SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 121 131 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 SUPERFAMILY SSF55486 23 157 2.69E-44 T 28-03-2018 SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 Pfam PF02130 Uncharacterized protein family UPF0054 27 151 1.7E-35 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 43 152 2.6E-37 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 Gene3D G3DSA:3.40.390.30 7 161 4.6E-48 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SmaCSM2_RS07090 066e22400dfc1e238a988011408bd6c4 161 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 7 155 23.931 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 SMART SM00382 36 223 5.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 SUPERFAMILY SSF52540 7 228 7.74E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 Gene3D G3DSA:3.40.50.300 3 258 3.8E-61 T 28-03-2018 SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 Pfam PF02687 FtsX-like permease family 557 645 2.2E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 Pfam PF12704 MacB-like periplasmic core domain 277 495 2.6E-42 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS06815 5dcabca42f0bca84ded75eca73f4790f 652 Pfam PF00005 ABC transporter 27 175 2.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 Gene3D G3DSA:3.40.50.2300 2 129 4.3E-26 T 28-03-2018 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.3E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.3E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.3E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 SMART SM00421 150 207 1.2E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 Gene3D G3DSA:1.10.10.10 130 212 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 SUPERFAMILY SSF46894 150 208 4.76E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 Pfam PF00072 Response regulator receiver domain 5 120 4.8E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 SUPERFAMILY SSF52172 2 134 2.13E-26 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS00820 88b4d08281f34cb4da5a0ed8899f2924 212 SMART SM00448 3 119 1.3E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09560 e07c1f2c0bde05c76bc172acec90d218 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 244 32.858 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 SmaCSM2_RS09560 e07c1f2c0bde05c76bc172acec90d218 244 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 240 4.7E-74 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 SmaCSM2_RS09560 e07c1f2c0bde05c76bc172acec90d218 244 SUPERFAMILY SSF51366 3 243 8.07E-64 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS09560 e07c1f2c0bde05c76bc172acec90d218 244 Gene3D G3DSA:3.20.20.70 4 244 6.5E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09560 e07c1f2c0bde05c76bc172acec90d218 244 Pfam PF00977 Histidine biosynthesis protein 5 236 4.2E-71 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SmaCSM2_RS10165 b16957c7767150f40afe8459e826c507 464 SUPERFAMILY SSF52540 117 384 2.55E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10165 b16957c7767150f40afe8459e826c507 464 SMART SM00382 181 365 7.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS10165 b16957c7767150f40afe8459e826c507 464 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 169 380 1.1E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS10165 b16957c7767150f40afe8459e826c507 464 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 40 460 3.4E-166 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SmaCSM2_RS10165 b16957c7767150f40afe8459e826c507 464 Gene3D G3DSA:3.40.50.300 94 380 1.3E-82 T 28-03-2018 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 SUPERFAMILY SSF51645 32 538 2.09E-179 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 Gene3D G3DSA:1.20.1220.12 423 539 7.0E-39 T 28-03-2018 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 Gene3D G3DSA:3.20.20.360 86 422 3.2E-117 T 28-03-2018 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 35 539 1.9E-211 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 Pfam PF01274 Malate synthase 28 539 1.6E-190 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SmaCSM2_RS01000 804acc4d8d95f598db43ef519c21531f 540 PIRSF PIRSF001363 12 540 1.9E-225 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SmaCSM2_RS05045 c00d2e9e10566db21abc5149e75ed4d7 163 Pfam PF01797 Transposase IS200 like 15 120 2.5E-10 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05045 c00d2e9e10566db21abc5149e75ed4d7 163 SUPERFAMILY SSF143422 9 133 4.05E-26 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05045 c00d2e9e10566db21abc5149e75ed4d7 163 Gene3D G3DSA:3.30.70.1290 6 134 5.5E-28 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05045 c00d2e9e10566db21abc5149e75ed4d7 163 SMART SM01321 13 127 4.7E-28 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS19995 e2132224c181d154ece3ddef36431a6b 93 Gene3D G3DSA:3.30.70.100 1 93 9.9E-4 T 28-03-2018 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 177 8.2E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 Gene3D G3DSA:2.170.130.10 43 188 2.4E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 SUPERFAMILY SSF56935 46 631 1.7E-107 T 28-03-2018 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 SUPERFAMILY SSF56935 661 776 1.7E-107 T 28-03-2018 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 60 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 Pfam PF00593 TonB dependent receptor 312 775 9.1E-39 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14810 883827ebb00cd1f8dc72509de4a48cb7 776 Gene3D G3DSA:2.40.170.20 190 776 3.5E-69 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06210 a654002b6c8e4e25583ef3831753fe1e 119 SUPERFAMILY SSF54593 9 118 5.37E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS06210 a654002b6c8e4e25583ef3831753fe1e 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 114 1.8E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS06210 a654002b6c8e4e25583ef3831753fe1e 119 Gene3D G3DSA:3.10.180.10 10 119 1.9E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS12375 d36dff2f885d135ff38abafe9b06b621 209 Gene3D G3DSA:1.20.1510.10 20 201 5.2E-25 T 28-03-2018 SmaCSM2_RS12375 d36dff2f885d135ff38abafe9b06b621 209 SUPERFAMILY SSF161111 20 200 1.57E-36 T 28-03-2018 SmaCSM2_RS12375 d36dff2f885d135ff38abafe9b06b621 209 Pfam PF01545 Cation efflux family 25 198 1.3E-20 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS17205 5d200c31d02446036d8d4b3c9497fcad 121 PIRSF PIRSF019455 1 121 2.1E-37 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SmaCSM2_RS17205 5d200c31d02446036d8d4b3c9497fcad 121 Gene3D G3DSA:1.10.10.10 5 66 3.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17205 5d200c31d02446036d8d4b3c9497fcad 121 SUPERFAMILY SSF46785 2 118 4.12E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17205 5d200c31d02446036d8d4b3c9497fcad 121 Pfam PF03965 Penicillinase repressor 4 117 3.0E-35 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SmaCSM2_RS17205 5d200c31d02446036d8d4b3c9497fcad 121 Gene3D G3DSA:1.10.4040.10 69 117 3.7E-13 T 28-03-2018 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 169 278 1.9E-22 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 SUPERFAMILY SSF48179 167 299 8.16E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 Gene3D G3DSA:3.40.50.720 1 174 8.0E-35 T 28-03-2018 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 Gene3D G3DSA:1.10.1040.10 175 301 7.1E-41 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 153 1.8E-43 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 234 261 2.1E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 2.1E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 2.1E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 112 137 2.1E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 158 186 2.1E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 SUPERFAMILY SSF51735 1 155 1.85E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 SMART SM01350 169 297 2.8E-5 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SmaCSM2_RS18300 61e30996c8543ec3753c25e69af0a10a 301 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 300 1.2E-114 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 SUPERFAMILY SSF103190 84 177 9.42E-6 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 SMART SM00267 355 520 7.4E-57 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 364 519 5.1E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 SUPERFAMILY SSF103190 190 266 1.18E-13 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 Pfam PF00990 Diguanylate cyclase, GGDEF domain 368 516 9.0E-40 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 Gene3D G3DSA:3.30.450.20 82 165 1.9E-11 T 28-03-2018 SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 Gene3D G3DSA:3.30.70.270 359 523 5.0E-52 T 28-03-2018 SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 SUPERFAMILY SSF55073 371 520 5.1E-46 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 Pfam PF02743 Cache domain 52 267 1.3E-21 T 28-03-2018 IPR033479 Double Cache domain 1 SmaCSM2_RS19465 bb1a9df4d9afc43dab0452a86fb88b80 524 Gene3D G3DSA:3.30.450.20 166 284 1.6E-18 T 28-03-2018 SmaCSM2_RS06015 146d402c91d10db2ea5e83dc6db595b7 113 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 24 97 5.7E-17 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 SmaCSM2_RS06015 146d402c91d10db2ea5e83dc6db595b7 113 SUPERFAMILY SSF103473 24 101 9.68E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06015 146d402c91d10db2ea5e83dc6db595b7 113 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 17 112 1.0E-37 T 28-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 SmaCSM2_RS10385 8c3ed5ba98697081cfc22e71641834e3 108 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 5 103 29.144 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS SmaCSM2_RS10385 8c3ed5ba98697081cfc22e71641834e3 108 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 26 104 9.1E-34 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 SmaCSM2_RS10385 8c3ed5ba98697081cfc22e71641834e3 108 Gene3D G3DSA:3.30.1390.10 15 107 4.0E-37 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SmaCSM2_RS10385 8c3ed5ba98697081cfc22e71641834e3 108 SUPERFAMILY SSF54736 23 107 5.75E-33 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SmaCSM2_RS20340 73771e6226e7d8ad1de317e4bf74b777 74 SUPERFAMILY SSF47413 8 70 8.31E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS20340 73771e6226e7d8ad1de317e4bf74b777 74 SMART SM00530 13 68 6.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS20340 73771e6226e7d8ad1de317e4bf74b777 74 Pfam PF01381 Helix-turn-helix 14 66 9.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS20340 73771e6226e7d8ad1de317e4bf74b777 74 Gene3D G3DSA:1.10.260.40 7 74 1.6E-17 T 28-03-2018 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Pfam PF00703 Glycosyl hydrolases family 2 229 338 2.6E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 SUPERFAMILY SSF49303 695 791 2.59E-6 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 SUPERFAMILY SSF49303 229 337 5.76E-17 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 SUPERFAMILY SSF49303 794 871 7.91E-13 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Gene3D G3DSA:2.60.40.10 692 786 3.9E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 356 486 1.7E-4 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Gene3D G3DSA:2.60.40.10 229 336 2.7E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Gene3D G3DSA:2.60.120.260 21 228 7.8E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Gene3D G3DSA:3.20.20.80 337 691 1.7E-79 T 28-03-2018 SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 Gene3D G3DSA:2.60.40.10 789 872 8.0E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 SUPERFAMILY SSF51445 335 693 2.52E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS09660 819e6c5456f5259ef53145b9395bcf13 872 SUPERFAMILY SSF49785 26 226 8.5E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 SUPERFAMILY SSF52833 8 93 9.41E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 Pfam PF00462 Glutaredoxin 12 71 6.6E-18 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 Gene3D G3DSA:3.40.30.10 11 96 8.1E-27 T 28-03-2018 SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 ProSitePatterns PS00195 Glutaredoxin active site. 14 30 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 PRINTS PR00160 Glutaredoxin signature 12 30 2.1E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 PRINTS PR00160 Glutaredoxin signature 54 67 2.1E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 PRINTS PR00160 Glutaredoxin signature 68 81 2.1E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup SmaCSM2_RS04340 d4343ad4046b1d83f1a924c585df2a7f 96 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 12 90 3.0E-34 T 28-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 2 60 1.1E-12 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 SUPERFAMILY SSF50249 131 187 8.0E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Gene3D G3DSA:2.40.50.140 66 129 2.2E-14 T 28-03-2018 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 1.7E-13 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Gene3D G3DSA:2.40.50.140 131 186 1.6E-20 T 28-03-2018 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 1 187 38.18 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 SUPERFAMILY SSF50249 68 128 5.57E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 PIRSF PIRSF005901 1 188 3.4E-60 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 7.2E-20 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 Gene3D G3DSA:2.30.30.30 1 61 4.5E-15 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 SMART SM01185 68 123 2.2E-15 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 SUPERFAMILY SSF50104 2 61 4.39E-9 T 28-03-2018 IPR008991 Translation protein SH3-like domain SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 2 187 2.4E-85 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 SMART SM00841 131 186 6.1E-24 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SmaCSM2_RS09760 9d71b9b4761607fc096cc1fbfe82dfc9 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site SmaCSM2_RS07805 2c1d2c8f125d8f8b3aef0f89a45aeaa2 250 Gene3D G3DSA:1.10.287.540 143 166 5.5E-4 T 28-03-2018 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.1E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 SUPERFAMILY SSF46689 3 83 2.39E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 Gene3D G3DSA:1.10.357.10 64 207 2.3E-21 T 28-03-2018 SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 SUPERFAMILY SSF48498 83 203 1.05E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS11020 2ef5adec1eec7cb81329b5f5067181a2 207 Gene3D G3DSA:1.10.10.60 1 63 6.8E-20 T 28-03-2018 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SMART SM00387 862 970 3.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Pfam PF00512 His Kinase A (phospho-acceptor) domain 753 818 9.6E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SUPERFAMILY SSF55785 588 713 3.14E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Pfam PF12860 PAS fold 603 719 1.3E-36 T 28-03-2018 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SUPERFAMILY SSF55874 808 966 1.02E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SUPERFAMILY SSF52172 988 1104 2.42E-14 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Gene3D G3DSA:3.30.565.10 822 974 5.3E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Gene3D G3DSA:1.10.287.130 743 814 8.8E-8 T 28-03-2018 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SMART SM00448 990 1099 1.7E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Pfam PF00072 Response regulator receiver domain 992 1099 3.7E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Gene3D G3DSA:3.30.450.20 579 733 4.2E-17 T 28-03-2018 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Gene3D G3DSA:3.40.50.2300 980 1108 8.8E-15 T 28-03-2018 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 863 966 9.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SMART SM00388 753 818 9.7E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 912 2.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 930 948 2.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 916 926 2.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 954 967 2.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11435 40afc3653a09e46977238faa7a5ea738 1111 SUPERFAMILY SSF47384 739 819 1.24E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16420 caf6e95842a7f7d12d116bcab47915fb 131 SUPERFAMILY SSF51230 4 128 2.88E-44 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS16420 caf6e95842a7f7d12d116bcab47915fb 131 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 41.274 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SmaCSM2_RS16420 caf6e95842a7f7d12d116bcab47915fb 131 Gene3D G3DSA:2.40.50.100 6 131 2.0E-47 T 28-03-2018 SmaCSM2_RS16420 caf6e95842a7f7d12d116bcab47915fb 131 Pfam PF01597 Glycine cleavage H-protein 8 128 5.0E-46 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate SmaCSM2_RS16420 caf6e95842a7f7d12d116bcab47915fb 131 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 130 1.1E-49 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 SUPERFAMILY SSF56235 19 434 2.47E-128 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Pfam PF00310 Glutamine amidotransferases class-II 19 431 5.2E-150 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Gene3D G3DSA:3.60.20.10 19 442 6.6E-121 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Pfam PF01493 GXGXG motif 1241 1424 1.1E-75 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Gene3D G3DSA:2.160.20.60 1215 1482 1.3E-90 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Gene3D G3DSA:3.20.20.70 443 784 1.3E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Gene3D G3DSA:3.20.20.70 785 1212 2.2E-143 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Pfam PF01645 Conserved region in glutamate synthase 800 1163 6.3E-148 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 SUPERFAMILY SSF69336 1215 1470 8.89E-86 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 Pfam PF04898 Glutamate synthase central domain 463 744 7.6E-99 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 SmaCSM2_RS00410 7738aad65299ec6b9d6dc300cfe794ac 1484 SUPERFAMILY SSF51395 450 1195 7.33E-246 T 28-03-2018 SmaCSM2_RS20370 56ac399ea7303398c2cd11a7b15be528 90 Gene3D G3DSA:1.20.120.650 1 83 2.0E-20 T 28-03-2018 SmaCSM2_RS20370 56ac399ea7303398c2cd11a7b15be528 90 Pfam PF09204 Bacterial self-protective colicin-like immunity 2 81 1.9E-21 T 28-03-2018 IPR015287 Colicin D immunity protein domain GO:0015643|GO:0030153 SmaCSM2_RS20370 56ac399ea7303398c2cd11a7b15be528 90 SUPERFAMILY SSF101125 3 84 3.53E-14 T 28-03-2018 IPR015287 Colicin D immunity protein domain GO:0015643|GO:0030153 SmaCSM2_RS18360 55c50546eef478660a1003e7e7439fe3 370 Pfam PF01098 Cell cycle protein 21 362 1.5E-95 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SmaCSM2_RS18360 55c50546eef478660a1003e7e7439fe3 370 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 20 363 7.5E-116 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 SmaCSM2_RS18360 55c50546eef478660a1003e7e7439fe3 370 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SmaCSM2_RS02975 68a12603271396ec18d0ccd5fd666bc8 164 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 20 40 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02975 68a12603271396ec18d0ccd5fd666bc8 164 Pfam PF12019 Type II transport protein GspH 60 151 1.3E-8 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS02975 68a12603271396ec18d0ccd5fd666bc8 164 Gene3D G3DSA:3.55.40.10 52 158 8.9E-5 T 28-03-2018 SmaCSM2_RS02975 68a12603271396ec18d0ccd5fd666bc8 164 SUPERFAMILY SSF54523 23 147 1.41E-7 T 28-03-2018 SmaCSM2_RS12860 17de5f847eef4c2a36cfc694b39ccfa4 386 Pfam PF07969 Amidohydrolase family 68 366 7.6E-21 T 28-03-2018 IPR013108 Amidohydrolase 3 SmaCSM2_RS12860 17de5f847eef4c2a36cfc694b39ccfa4 386 Gene3D G3DSA:2.30.40.10 6 60 6.5E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12860 17de5f847eef4c2a36cfc694b39ccfa4 386 SUPERFAMILY SSF51556 52 356 3.97E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS12860 17de5f847eef4c2a36cfc694b39ccfa4 386 SUPERFAMILY SSF51338 18 66 8.97E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12860 17de5f847eef4c2a36cfc694b39ccfa4 386 Gene3D G3DSA:3.20.20.140 61 346 3.6E-30 T 28-03-2018 SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 SUPERFAMILY SSF54423 44 102 2.55E-10 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 Pfam PF10411 Disulfide bond isomerase protein N-terminus 48 100 1.2E-16 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 Pfam PF13098 Thioredoxin-like domain 129 253 1.7E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 SUPERFAMILY SSF52833 116 255 1.71E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 Gene3D G3DSA:3.40.30.10 120 260 2.2E-25 T 28-03-2018 SmaCSM2_RS02925 e9e27f4c64f3eeee0f93507d03fbeff6 260 Gene3D G3DSA:3.10.450.70 40 102 1.6E-18 T 28-03-2018 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 Gene3D G3DSA:1.10.10.10 1 85 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 Gene3D G3DSA:3.40.190.10 181 274 3.7E-21 T 28-03-2018 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 SUPERFAMILY SSF53850 90 301 4.25E-41 T 28-03-2018 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 Pfam PF03466 LysR substrate binding domain 89 299 3.0E-44 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 SUPERFAMILY SSF46785 4 88 3.29E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 Gene3D G3DSA:3.40.190.10 90 180 1.5E-19 T 28-03-2018 SmaCSM2_RS00990 41aeac0276d365a52a28383ef3832aea 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.6E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 97 302 4.8E-27 T 28-03-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 136 155 3.6E-5 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 159 173 3.6E-5 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 299 310 3.6E-5 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 246 260 3.6E-5 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 Gene3D G3DSA:3.90.15.10 95 242 3.4E-32 T 28-03-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 Gene3D G3DSA:3.30.66.10 29 94 1.4E-34 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 SUPERFAMILY SSF56349 92 319 1.09E-63 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 Gene3D G3DSA:1.20.120.380 248 333 2.1E-27 T 28-03-2018 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 SmaCSM2_RS00420 a97a8c46bceec5bcef45094f34a79a34 352 SUPERFAMILY SSF55869 36 96 9.55E-22 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal SmaCSM2_RS05300 c386f57921dd9503154daa231f7e5dac 216 SMART SM01321 9 124 2.7E-43 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05300 c386f57921dd9503154daa231f7e5dac 216 Pfam PF01797 Transposase IS200 like 14 122 6.5E-17 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05300 c386f57921dd9503154daa231f7e5dac 216 SUPERFAMILY SSF143422 3 127 2.09E-31 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS05300 c386f57921dd9503154daa231f7e5dac 216 Gene3D G3DSA:3.30.70.1290 3 131 9.6E-29 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 Gene3D G3DSA:3.55.40.10 36 147 4.2E-19 T 28-03-2018 SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 6 146 5.0E-28 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 SUPERFAMILY SSF54523 8 124 7.85E-13 T 28-03-2018 SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 7.7E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 27 1.3E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12120 2c53bc93f135cb172c1ef5145e3aeec9 148 Pfam PF12019 Type II transport protein GspH 46 137 2.5E-6 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 Pfam PF00593 TonB dependent receptor 469 931 3.0E-25 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 Gene3D G3DSA:2.170.130.10 154 295 2.5E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 Gene3D G3DSA:2.40.170.20 298 931 1.3E-40 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 SUPERFAMILY SSF56935 694 930 1.87E-74 T 28-03-2018 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 SUPERFAMILY SSF56935 134 343 1.87E-74 T 28-03-2018 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 SUPERFAMILY SSF56935 391 656 1.87E-74 T 28-03-2018 SmaCSM2_RS05955 f8e9c1a06aa60c060a4c3829b4959e42 931 Pfam PF07715 TonB-dependent Receptor Plug Domain 159 280 2.7E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:3.30.70.1430 44 139 1.4E-17 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:3.30.2090.10 721 807 6.7E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82714 185 267 3.14E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1038 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82866 294 503 2.62E-39 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82866 805 1037 4.05E-44 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:1.20.1640.10 824 1046 1.7E-31 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:1.20.1640.10 286 516 2.4E-45 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:3.30.70.1430 565 663 3.0E-9 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Gene3D G3DSA:3.30.2090.10 183 269 6.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82693 45 127 8.63E-19 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 2.2E-24 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82714 721 806 1.96E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82693 137 184 2.3E-18 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 SUPERFAMILY SSF82693 270 327 2.3E-18 T 28-03-2018 SmaCSM2_RS10815 d908733dd25ffae0f29f1cf01ff50596 1046 Pfam PF00873 AcrB/AcrD/AcrF family 7 1034 6.0E-224 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 Pfam PF08274 PhnA Zinc-Ribbon 5 32 6.7E-11 T 28-03-2018 IPR013987 PhnA protein, N-terminal SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 111 8.2E-32 T 28-03-2018 IPR004624 PhnA protein SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 SUPERFAMILY SSF82057 41 111 1.92E-24 T 28-03-2018 SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 Gene3D G3DSA:2.20.25.10 2 40 5.1E-12 T 28-03-2018 SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 Pfam PF03831 PhnA domain 43 111 1.8E-30 T 28-03-2018 IPR013988 PhnA protein, C-terminal SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 Gene3D G3DSA:2.30.30.40 42 110 2.6E-30 T 28-03-2018 SmaCSM2_RS15755 f8c0256940c1b8cc4ded48d4cfc6d5a7 111 SUPERFAMILY SSF57783 3 36 3.23E-11 T 28-03-2018 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 PIRSF PIRSF001554 1 388 6.5E-149 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 SUPERFAMILY SSF52210 239 385 1.7E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 41.788 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Pfam PF08442 ATP-grasp domain 2 202 1.3E-72 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 4.6E-156 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Gene3D G3DSA:3.30.1490.20 32 102 6.1E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Pfam PF00549 CoA-ligase 262 380 6.6E-26 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Gene3D G3DSA:3.40.50.261 2 31 0.45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Gene3D G3DSA:3.40.50.261 240 385 1.5E-43 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 Gene3D G3DSA:3.30.470.20 103 239 1.2E-47 T 28-03-2018 SmaCSM2_RS16905 aee1ff34ac39e09578d606e287b0c2dc 389 SUPERFAMILY SSF56059 1 238 6.36E-76 T 28-03-2018 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 Pfam PF00072 Response regulator receiver domain 14 125 4.2E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 SUPERFAMILY SSF46894 135 203 3.74E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.2E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.2E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.2E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 Gene3D G3DSA:1.10.10.10 145 206 2.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 200 1.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 SMART SM00421 145 202 8.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 SMART SM00448 10 125 1.5E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 SUPERFAMILY SSF52172 7 134 3.13E-12 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10525 00b8c28321be6c0da8cd430228bdfb7d 208 Gene3D G3DSA:3.40.50.2300 9 144 1.2E-14 T 28-03-2018 SmaCSM2_RS18565 cb22e3944047e8f8bfc0ba1a53cb4261 676 SUPERFAMILY SSF55486 5 674 2.56E-194 T 28-03-2018 SmaCSM2_RS18565 cb22e3944047e8f8bfc0ba1a53cb4261 676 Gene3D G3DSA:1.10.1370.10 141 434 2.0E-53 T 28-03-2018 SmaCSM2_RS18565 cb22e3944047e8f8bfc0ba1a53cb4261 676 Gene3D G3DSA:1.10.1370.10 455 676 9.5E-64 T 28-03-2018 SmaCSM2_RS18565 cb22e3944047e8f8bfc0ba1a53cb4261 676 Pfam PF01432 Peptidase family M3 227 674 3.0E-141 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SmaCSM2_RS18565 cb22e3944047e8f8bfc0ba1a53cb4261 676 Gene3D G3DSA:1.20.1050.40 7 139 4.1E-33 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 97 108 - T 28-03-2018 IPR018215 ClpP, Ser active site SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 SUPERFAMILY SSF52096 17 200 4.97E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 9 199 2.9E-105 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 Gene3D G3DSA:3.90.226.10 9 201 1.3E-44 T 28-03-2018 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 10 200 44.01 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 119 132 - T 28-03-2018 IPR033135 ClpP, histidine active site SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 Pfam PF00574 Clp protease 19 199 7.4E-87 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 PRINTS PR00127 Clp protease catalytic subunit P signature 26 41 5.7E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 PRINTS PR00127 Clp protease catalytic subunit P signature 175 194 5.7E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 PRINTS PR00127 Clp protease catalytic subunit P signature 97 114 5.7E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 PRINTS PR00127 Clp protease catalytic subunit P signature 118 137 5.7E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS04420 71ec00dffccccd423c63a53c6db7a059 208 PRINTS PR00127 Clp protease catalytic subunit P signature 66 86 5.7E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SmaCSM2_RS06595 a98b7ab9c08feadeb162dd9a98307a10 152 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 9 151 34.253 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS06595 a98b7ab9c08feadeb162dd9a98307a10 152 Pfam PF07977 FabA-like domain 18 143 3.8E-39 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS06595 a98b7ab9c08feadeb162dd9a98307a10 152 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 9 148 5.4E-60 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS06595 a98b7ab9c08feadeb162dd9a98307a10 152 Gene3D G3DSA:3.10.129.10 2 152 4.8E-52 T 28-03-2018 SmaCSM2_RS06595 a98b7ab9c08feadeb162dd9a98307a10 152 SUPERFAMILY SSF54637 8 148 1.73E-45 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 SUPERFAMILY SSF48452 44 123 4.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 Gene3D G3DSA:1.25.40.10 186 279 0.0012 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 Gene3D G3DSA:1.25.40.10 44 185 7.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 13 260 2.3E-77 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 Pfam PF13525 Outer membrane lipoprotein 43 247 5.7E-56 T 28-03-2018 SmaCSM2_RS16885 bb02bdb1b77d1934a3d55dd3e9a71cb6 295 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 11 254 34.821 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 SUPERFAMILY SSF55120 61 226 1.76E-36 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 Pfam PF00849 RNA pseudouridylate synthase 61 193 8.2E-14 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 Gene3D G3DSA:3.10.290.10 1 55 1.8E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 Gene3D G3DSA:3.30.70.1560 141 210 4.3E-19 T 28-03-2018 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 64 223 2.7E-38 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS02460 9cdaa2dd87a2cb961fcd8794abc25ecd 233 Gene3D G3DSA:3.30.70.580 59 140 1.6E-12 T 28-03-2018 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 SUPERFAMILY SSF118215 12 415 7.98E-102 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 Pfam PF00375 Sodium:dicarboxylate symporter family 13 415 6.7E-114 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 308 334 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 343 362 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 159 181 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 PRINTS PR00173 Glutamate-aspartate symporter signature 370 390 4.4E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS15505 81aa1c13fdeacc06182c703882f9d2a8 444 Gene3D G3DSA:1.10.3860.10 1 423 1.1E-110 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 Hamap MF_00384 Homoserine kinase [thrB]. 3 303 28.059 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 SUPERFAMILY SSF54211 4 162 9.87E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 Gene3D G3DSA:3.30.70.890 162 304 8.0E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PRINTS PR00958 Homoserine kinase signature 249 264 8.3E-23 T 28-03-2018 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PRINTS PR00958 Homoserine kinase signature 10 25 8.3E-23 T 28-03-2018 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PRINTS PR00958 Homoserine kinase signature 95 110 8.3E-23 T 28-03-2018 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PRINTS PR00958 Homoserine kinase signature 170 187 8.3E-23 T 28-03-2018 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PRINTS PR00958 Homoserine kinase signature 135 148 8.3E-23 T 28-03-2018 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 Pfam PF08544 GHMP kinases C terminal 209 283 2.4E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 PIRSF PIRSF000676 1 304 1.0E-70 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 Pfam PF00288 GHMP kinases N terminal domain 82 148 2.7E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 SUPERFAMILY SSF55060 167 280 1.24E-20 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SmaCSM2_RS09505 5763d32caed8de314ee06301af59aba2 304 Gene3D G3DSA:3.30.230.10 6 158 1.6E-22 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 Pfam PF00255 Glutathione peroxidase 5 110 1.8E-39 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 SUPERFAMILY SSF52833 2 159 2.05E-59 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 Gene3D G3DSA:3.40.30.10 2 159 5.0E-43 T 28-03-2018 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 PIRSF PIRSF000303 1 159 1.3E-61 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 PRINTS PR01011 Glutathione peroxidase family signature 22 39 9.0E-20 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 PRINTS PR01011 Glutathione peroxidase family signature 57 73 9.0E-20 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14280 6b51b147ca29695ae4fdc97adaa9f51c 159 PRINTS PR01011 Glutathione peroxidase family signature 123 132 9.0E-20 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS02865 173a4c09e8900d072d0f338e67046a21 258 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 57 79 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS02865 173a4c09e8900d072d0f338e67046a21 258 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 79 1.2E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS02865 173a4c09e8900d072d0f338e67046a21 258 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 24 192 4.4E-33 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 SmaCSM2_RS16220 7d718d08af134a3b0ef4dfef348383f6 155 Gene3D G3DSA:3.40.630.30 6 150 4.5E-25 T 28-03-2018 SmaCSM2_RS16220 7d718d08af134a3b0ef4dfef348383f6 155 PIRSF PIRSF000452 3 150 5.5E-43 T 28-03-2018 IPR024170 Aminoglycoside N6-acetyltransferase SmaCSM2_RS16220 7d718d08af134a3b0ef4dfef348383f6 155 Pfam PF00583 Acetyltransferase (GNAT) family 27 136 1.8E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS16220 7d718d08af134a3b0ef4dfef348383f6 155 SUPERFAMILY SSF55729 7 146 6.52E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 1 265 19.747 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 Pfam PF13525 Outer membrane lipoprotein 145 266 8.0E-11 T 28-03-2018 SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 Pfam PF16331 TolA binding protein trimerisation 27 100 1.5E-18 T 28-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 Gene3D G3DSA:1.25.40.10 146 272 3.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 145 262 3.7E-38 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 SUPERFAMILY SSF48452 147 258 4.8E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16665 30e07883220642a6286c90af798162c1 272 Gene3D G3DSA:1.20.5.50 21 100 1.3E-5 T 28-03-2018 SmaCSM2_RS08895 334b54ce8a315bad468feeecadd258e0 178 Pfam PF00156 Phosphoribosyl transferase domain 43 160 1.9E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SmaCSM2_RS08895 334b54ce8a315bad468feeecadd258e0 178 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 10 178 34.652 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SmaCSM2_RS08895 334b54ce8a315bad468feeecadd258e0 178 Gene3D G3DSA:3.40.50.2020 5 177 5.8E-40 T 28-03-2018 SmaCSM2_RS08895 334b54ce8a315bad468feeecadd258e0 178 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 12 173 5.5E-62 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SmaCSM2_RS08895 334b54ce8a315bad468feeecadd258e0 178 SUPERFAMILY SSF53271 11 168 2.62E-48 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 SUPERFAMILY SSF55821 2 202 1.42E-84 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 PIRSF PIRSF001259 1 366 2.1E-118 T 28-03-2018 SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 38.259 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 Pfam PF00925 GTP cyclohydrolase II 208 364 8.1E-28 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 Gene3D G3DSA:3.90.870.10 1 212 3.2E-95 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 SUPERFAMILY SSF142695 204 365 4.71E-40 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 5.2E-84 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03145 aec0bff81468af13e339e7deaa52ed73 366 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 1.4E-72 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS12270 4583a4baf90dd60edfb2b1a718cbb509 443 Gene3D G3DSA:1.20.1250.20 8 203 1.3E-28 T 28-03-2018 SmaCSM2_RS12270 4583a4baf90dd60edfb2b1a718cbb509 443 Gene3D G3DSA:1.20.1250.20 207 423 9.1E-33 T 28-03-2018 SmaCSM2_RS12270 4583a4baf90dd60edfb2b1a718cbb509 443 Pfam PF07690 Major Facilitator Superfamily 22 252 2.1E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS12270 4583a4baf90dd60edfb2b1a718cbb509 443 SUPERFAMILY SSF103473 10 425 1.15E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS15695 612659ffc9af4eb26fd209bc68377896 134 SUPERFAMILY SSF54593 7 132 1.61E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS15695 612659ffc9af4eb26fd209bc68377896 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 129 1.1E-19 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS15695 612659ffc9af4eb26fd209bc68377896 134 Gene3D G3DSA:3.10.180.10 2 134 9.1E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SUPERFAMILY SSF55073 558 712 9.42E-46 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Gene3D G3DSA:3.30.450.20 144 288 6.7E-31 T 28-03-2018 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Gene3D G3DSA:3.30.450.20 289 411 8.5E-32 T 28-03-2018 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Gene3D G3DSA:3.30.450.20 412 555 9.3E-15 T 28-03-2018 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Gene3D G3DSA:3.30.450.20 11 143 1.9E-25 T 28-03-2018 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SUPERFAMILY SSF55785 140 282 1.61E-23 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 551 712 4.5E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SUPERFAMILY SSF55785 29 146 4.01E-21 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Pfam PF00990 Diguanylate cyclase, GGDEF domain 553 709 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SUPERFAMILY SSF55785 281 409 1.15E-28 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Gene3D G3DSA:3.30.70.270 556 718 1.9E-55 T 28-03-2018 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Pfam PF13426 PAS domain 168 283 2.7E-12 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SUPERFAMILY SSF55785 408 538 1.26E-9 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Pfam PF08447 PAS fold 320 403 4.3E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Pfam PF08447 PAS fold 47 136 1.2E-19 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 Pfam PF08448 PAS fold 429 543 8.5E-7 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00267 542 713 7.8E-61 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00091 24 93 7.5E-4 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00091 296 362 7.3E-12 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00091 423 490 27.0 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00091 155 223 3.3E-8 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 290 1.5E-17 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 148 1.3E-12 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 294 418 1.6E-26 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00086 369 411 4.0E-12 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00086 242 284 3.8E-5 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS13215 057dd8a18e8399e7982924fa4076fef1 727 SMART SM00086 100 143 9.1E-5 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS07535 9a01539042d906defbac99ba476941db 506 Pfam PF07916 TraG-like protein, N-terminal region 10 489 1.4E-97 T 28-03-2018 IPR012931 TraG-like, N-terminal SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 Pfam PF04060 Putative Fe-S cluster 15 47 4.0E-15 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 136 3.3E-66 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 Gene3D G3DSA:3.30.70.20 97 117 1.7E-8 T 28-03-2018 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 Pfam PF14697 4Fe-4S dicluster domain 80 134 3.8E-16 T 28-03-2018 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 Gene3D G3DSA:3.30.70.20 14 96 2.1E-10 T 28-03-2018 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 SUPERFAMILY SSF54862 10 136 1.79E-28 T 28-03-2018 SmaCSM2_RS15715 3121f1e42941b1e556a52fe0fdf311b5 137 Gene3D G3DSA:3.30.70.20 118 137 0.0014 T 28-03-2018 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 Hamap MF_00303 Trigger factor [tig]. 1 424 17.95 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 Gene3D G3DSA:3.30.70.1050 1 113 1.3E-26 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 SUPERFAMILY SSF102735 1 126 4.84E-29 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 SUPERFAMILY SSF54534 129 241 9.01E-17 T 28-03-2018 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 Pfam PF05697 Bacterial trigger factor protein (TF) 1 141 5.8E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 TIGRFAM TIGR00115 tig: trigger factor 11 412 5.0E-108 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 SUPERFAMILY SSF109998 245 429 6.38E-38 T 28-03-2018 IPR027304 Trigger factor/SurA domain SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 PIRSF PIRSF003095 1 431 1.1E-104 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 260 414 6.8E-35 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SmaCSM2_RS04415 ae91b539d38756439235c6af0435b958 431 Gene3D G3DSA:1.10.3120.10 208 390 9.2E-36 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SmaCSM2_RS01475 fc731deb0bacb940d341d32f503d01df 404 SMART SM00387 299 388 9.8E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01475 fc731deb0bacb940d341d32f503d01df 404 SUPERFAMILY SSF55874 275 386 1.45E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01475 fc731deb0bacb940d341d32f503d01df 404 Gene3D G3DSA:3.30.565.10 248 392 5.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01475 fc731deb0bacb940d341d32f503d01df 404 Pfam PF07730 Histidine kinase 203 269 3.6E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SmaCSM2_RS11330 46123fd2291bf314b71407739f3f41b2 477 Gene3D G3DSA:2.40.160.10 87 477 8.2E-39 T 28-03-2018 SmaCSM2_RS11330 46123fd2291bf314b71407739f3f41b2 477 Pfam PF07396 Phosphate-selective porin O and P 119 477 2.2E-24 T 28-03-2018 IPR010870 Phosphate-selective porin O/P SmaCSM2_RS11330 46123fd2291bf314b71407739f3f41b2 477 SUPERFAMILY SSF56935 229 377 4.03E-8 T 28-03-2018 SmaCSM2_RS11330 46123fd2291bf314b71407739f3f41b2 477 SUPERFAMILY SSF56935 405 477 4.03E-8 T 28-03-2018 SmaCSM2_RS11330 46123fd2291bf314b71407739f3f41b2 477 SUPERFAMILY SSF56935 119 200 4.03E-8 T 28-03-2018 SmaCSM2_RS10555 8cc2de5ea6388e40c18ae4b520de1a19 419 PIRSF PIRSF003085 18 415 4.1E-123 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SmaCSM2_RS10555 8cc2de5ea6388e40c18ae4b520de1a19 419 SUPERFAMILY SSF53335 21 360 4.18E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS10555 8cc2de5ea6388e40c18ae4b520de1a19 419 Gene3D G3DSA:3.40.50.150 127 406 2.2E-61 T 28-03-2018 SmaCSM2_RS10555 8cc2de5ea6388e40c18ae4b520de1a19 419 Pfam PF02353 Mycolic acid cyclopropane synthetase 133 401 1.2E-82 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 43 296 1.3E-61 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 Pfam PF02355 Protein export membrane protein 122 301 9.5E-48 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 Pfam PF07549 SecD/SecF GG Motif 38 64 4.6E-10 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 Gene3D G3DSA:1.20.1640.10 55 311 7.8E-19 T 28-03-2018 SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 15 306 28.692 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 PRINTS PR01755 Bacterial translocase SecF protein signature 244 259 2.4E-28 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 PRINTS PR01755 Bacterial translocase SecF protein signature 42 57 2.4E-28 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 PRINTS PR01755 Bacterial translocase SecF protein signature 213 231 2.4E-28 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 PRINTS PR01755 Bacterial translocase SecF protein signature 165 179 2.4E-28 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 103 293 1.4E-44 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08840 12b581b47c40c4ef4c66d6372d581eac 326 SUPERFAMILY SSF82866 82 302 1.83E-30 T 28-03-2018 SmaCSM2_RS18860 29efad12253e05d2b73ccf12fc5713bc 494 SUPERFAMILY SSF51445 89 225 1.3E-13 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS18860 29efad12253e05d2b73ccf12fc5713bc 494 Pfam PF14488 Domain of unknown function (DUF4434) 23 191 8.8E-21 T 28-03-2018 IPR027849 Protein of unknown function DUF4434 SmaCSM2_RS18860 29efad12253e05d2b73ccf12fc5713bc 494 Gene3D G3DSA:3.20.20.80 20 330 4.3E-13 T 28-03-2018 SmaCSM2_RS18860 29efad12253e05d2b73ccf12fc5713bc 494 Gene3D G3DSA:2.60.120.260 331 494 0.0013 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 Pfam PF01220 Dehydroquinase class II 3 140 2.3E-58 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 PIRSF PIRSF001399 1 147 2.7E-55 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 140 2.7E-53 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 71.995 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 Gene3D G3DSA:3.40.50.9100 1 147 1.4E-63 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 SUPERFAMILY SSF52304 3 143 8.63E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS19320 5c28fc79b6659cfcf75101084705c88c 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 141 3.0E-42 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS02780 495e4c99794c2eb906bc5426a05a8f21 185 SUPERFAMILY SSF51182 2 176 1.86E-73 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS02780 495e4c99794c2eb906bc5426a05a8f21 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 175 1.7E-79 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SmaCSM2_RS02780 495e4c99794c2eb906bc5426a05a8f21 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 175 4.0E-84 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SmaCSM2_RS02780 495e4c99794c2eb906bc5426a05a8f21 185 Gene3D G3DSA:2.60.120.10 1 181 4.5E-76 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS02780 495e4c99794c2eb906bc5426a05a8f21 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 1.4E-72 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 Pfam PF00271 Helicase conserved C-terminal domain 307 411 1.9E-14 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 Pfam PF09369 Domain of unknown function (DUF1998) 675 780 1.8E-12 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 SMART SM00487 74 278 5.7E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 SMART SM00490 324 412 9.2E-16 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 Gene3D G3DSA:3.40.50.300 293 443 9.5E-24 T 28-03-2018 SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 Gene3D G3DSA:3.40.50.300 4 270 7.9E-36 T 28-03-2018 SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 SUPERFAMILY SSF52540 90 250 6.1E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 SUPERFAMILY SSF52540 279 418 6.1E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00470 9ff8e462a1a8534f996ef5192920b7d7 829 Pfam PF00270 DEAD/DEAH box helicase 80 248 1.4E-27 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 SUPERFAMILY SSF46785 4 111 2.99E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 Gene3D G3DSA:3.40.190.10 90 175 2.0E-14 T 28-03-2018 SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 Gene3D G3DSA:1.10.10.10 3 89 3.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 Gene3D G3DSA:3.40.190.10 176 262 2.3E-28 T 28-03-2018 SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 Pfam PF03466 LysR substrate binding domain 89 289 2.6E-43 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS02500 3057d2c968b5360ff160fae782f7dbae 309 SUPERFAMILY SSF53850 89 294 1.81E-47 T 28-03-2018 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 SUPERFAMILY SSF48179 184 307 2.48E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 185 306 4.0E-21 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 Gene3D G3DSA:3.40.50.720 1 182 1.5E-29 T 28-03-2018 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 308 8.4E-59 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 SUPERFAMILY SSF51735 1 139 2.99E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 156 8.3E-38 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SmaCSM2_RS20935 ba30b4a5683653cf94fe3f9a77a5c50b 312 Gene3D G3DSA:1.10.1040.10 183 311 2.7E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 234 251 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 322 345 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 278 296 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 199 220 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 297 318 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 PRINTS PR00721 Stomatin signature 254 277 1.1E-12 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 SMART SM00244 143 302 1.1E-16 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 SUPERFAMILY SSF117892 182 308 1.26E-25 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS20985 72b67a6f049173e8923a5d5b3b18aae1 374 Pfam PF01145 SPFH domain / Band 7 family 147 319 3.2E-24 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 SUPERFAMILY SSF51338 12 70 3.19E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 SUPERFAMILY SSF51338 368 442 3.19E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 Pfam PF01979 Amidohydrolase family 68 415 2.5E-64 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 Gene3D G3DSA:2.30.40.10 2 81 6.7E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 Gene3D G3DSA:3.20.20.140 82 368 1.6E-55 T 28-03-2018 SmaCSM2_RS14690 bfd2f47f13d743cc8f58ee2c28cd3a08 447 SUPERFAMILY SSF51556 70 369 5.9E-93 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 Gene3D G3DSA:3.30.70.1560 168 242 2.7E-18 T 28-03-2018 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 Gene3D G3DSA:3.30.70.580 78 167 4.5E-14 T 28-03-2018 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 SUPERFAMILY SSF55120 83 256 4.32E-36 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 Pfam PF00849 RNA pseudouridylate synthase 87 222 1.7E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 Pfam PF01479 S4 domain 24 69 3.8E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 91 253 1.8E-49 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 Gene3D G3DSA:3.10.290.10 22 76 2.1E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 SUPERFAMILY SSF55174 21 110 2.8E-17 T 28-03-2018 SmaCSM2_RS14435 c966aa2cfc1cbecbeeeccccf17472b75 544 SMART SM00363 24 82 7.6E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 Pfam PF00120 Glutamine synthetase, catalytic domain 126 459 1.4E-106 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 Gene3D G3DSA:3.10.20.70 16 124 1.1E-24 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 SUPERFAMILY SSF55931 125 462 6.47E-109 T 28-03-2018 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 SMART SM01230 125 384 2.4E-108 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 Gene3D G3DSA:3.30.590.10 125 464 2.1E-95 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 SUPERFAMILY SSF54368 20 124 1.31E-23 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SmaCSM2_RS07035 00e87ed6deba647a9c38acfcc52035e9 465 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 SUPERFAMILY SSF54637 4 136 8.87E-41 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 PIRSF PIRSF003230 1 140 3.5E-42 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 Gene3D G3DSA:3.10.129.10 2 143 5.5E-39 T 28-03-2018 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 7 129 9.9E-51 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 12 29 - T 28-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 Pfam PF03061 Thioesterase superfamily 21 105 4.4E-21 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SmaCSM2_RS16695 a01d5d7532fe2bb73b9b395cfe367bc3 143 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 10 116 4.7E-34 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 SmaCSM2_RS02750 ce3180bcaadacee54c34054792be9dd6 471 Pfam PF01040 UbiA prenyltransferase family 209 448 1.4E-19 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SmaCSM2_RS02750 ce3180bcaadacee54c34054792be9dd6 471 Gene3D G3DSA:3.40.50.1000 1 181 4.5E-9 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02750 ce3180bcaadacee54c34054792be9dd6 471 SUPERFAMILY SSF56784 58 170 9.92E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02750 ce3180bcaadacee54c34054792be9dd6 471 SUPERFAMILY SSF56784 5 22 9.92E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS00800 805d2e3f79a3d3fa58f08f26525728a9 374 SUPERFAMILY SSF56112 44 333 1.9E-38 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS00800 805d2e3f79a3d3fa58f08f26525728a9 374 Gene3D G3DSA:3.90.1200.10 131 333 1.1E-16 T 28-03-2018 SmaCSM2_RS00800 805d2e3f79a3d3fa58f08f26525728a9 374 Pfam PF01636 Phosphotransferase enzyme family 58 279 1.1E-24 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SmaCSM2_RS00800 805d2e3f79a3d3fa58f08f26525728a9 374 Gene3D G3DSA:3.30.200.20 50 121 4.3E-10 T 28-03-2018 SmaCSM2_RS16785 4b280c4d52027e57d5f052ae4b47d07a 565 Pfam PF00999 Sodium/hydrogen exchanger family 13 388 1.2E-75 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS16785 4b280c4d52027e57d5f052ae4b47d07a 565 Gene3D G3DSA:3.40.50.720 413 552 7.6E-21 T 28-03-2018 SmaCSM2_RS16785 4b280c4d52027e57d5f052ae4b47d07a 565 SUPERFAMILY SSF51735 420 550 1.41E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16785 4b280c4d52027e57d5f052ae4b47d07a 565 Gene3D G3DSA:1.20.91.10 243 324 1.4E-7 T 28-03-2018 SmaCSM2_RS16785 4b280c4d52027e57d5f052ae4b47d07a 565 Pfam PF02254 TrkA-N domain 422 534 2.3E-22 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 SUPERFAMILY SSF53720 21 449 7.46E-112 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 214 221 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 Gene3D G3DSA:3.40.605.10 1 233 1.3E-62 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 PIRSF PIRSF036492 1 469 6.8E-155 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 Pfam PF00171 Aldehyde dehydrogenase family 25 436 2.4E-88 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS21370 c4f91ca567801a62b26c200b0f1a6610 469 Gene3D G3DSA:3.40.309.10 234 421 2.5E-54 T 28-03-2018 SmaCSM2_RS18235 8e9775d10dc143f8cbc98fd50f7bd76d 338 Pfam PF02685 Glucokinase 20 334 1.7E-97 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SmaCSM2_RS18235 8e9775d10dc143f8cbc98fd50f7bd76d 338 Gene3D G3DSA:3.30.420.40 8 132 6.9E-17 T 28-03-2018 SmaCSM2_RS18235 8e9775d10dc143f8cbc98fd50f7bd76d 338 SUPERFAMILY SSF53067 19 335 6.29E-51 T 28-03-2018 SmaCSM2_RS18235 8e9775d10dc143f8cbc98fd50f7bd76d 338 Gene3D G3DSA:3.40.367.20 133 318 4.1E-27 T 28-03-2018 SmaCSM2_RS18910 a6e54b030d15acf5806c59fc1e03284c 341 Gene3D G3DSA:1.10.10.10 123 282 3.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18910 a6e54b030d15acf5806c59fc1e03284c 341 SUPERFAMILY SSF46785 132 220 9.67E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05590 df772c4b9e2971b6a23b7a9906522285 378 SUPERFAMILY SSF56300 152 375 1.08E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS05590 df772c4b9e2971b6a23b7a9906522285 378 Pfam PF00149 Calcineurin-like phosphoesterase 152 317 2.1E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS05590 df772c4b9e2971b6a23b7a9906522285 378 Gene3D G3DSA:3.60.21.10 148 375 9.1E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS20220 9f643a298f18afced50d9e08f77d5356 296 Gene3D G3DSA:3.60.110.10 1 279 7.3E-45 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS20220 9f643a298f18afced50d9e08f77d5356 296 SUPERFAMILY SSF56317 1 269 2.62E-47 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS20220 9f643a298f18afced50d9e08f77d5356 296 Pfam PF00795 Carbon-nitrogen hydrolase 3 213 7.1E-22 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 253 1.1E-83 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 SUPERFAMILY SSF54292 28 129 4.3E-31 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 SUPERFAMILY SSF46548 131 258 1.06E-39 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 Gene3D G3DSA:3.10.20.30 18 129 4.1E-37 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 Pfam PF13534 4Fe-4S dicluster domain 171 244 7.0E-10 T 28-03-2018 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 Gene3D G3DSA:1.10.1060.10 130 261 2.3E-31 T 28-03-2018 SmaCSM2_RS08450 db3d0d80be0eaf564c1187c4aab6623e 261 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 29 134 8.4E-34 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS17400 47dfcc5196d449c915e6c1aa0b49346f 215 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 9 207 7.1E-58 T 28-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 SmaCSM2_RS17400 47dfcc5196d449c915e6c1aa0b49346f 215 Gene3D G3DSA:1.20.950.20 5 215 7.8E-50 T 28-03-2018 SmaCSM2_RS17400 47dfcc5196d449c915e6c1aa0b49346f 215 SUPERFAMILY SSF81342 7 210 2.2E-52 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SmaCSM2_RS17400 47dfcc5196d449c915e6c1aa0b49346f 215 Pfam PF01292 Prokaryotic cytochrome b561 12 188 4.0E-25 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 84 104 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 254 270 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 164 179 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 141 161 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 115 139 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 63 78 3.5E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 11 293 6.5E-149 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 SUPERFAMILY SSF55681 10 293 6.59E-133 T 28-03-2018 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 Gene3D G3DSA:3.30.930.10 2 217 9.1E-85 T 28-03-2018 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 Gene3D G3DSA:1.20.58.180 219 295 1.4E-34 T 28-03-2018 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 10 302 7.1E-160 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS21435 1aaa9c76afb63e20d4e886f6b79679e0 303 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 9 294 59.911 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 Gene3D G3DSA:3.20.20.140 114 447 2.3E-25 T 28-03-2018 SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 SUPERFAMILY SSF51556 103 256 5.78E-36 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 SUPERFAMILY SSF51556 293 431 5.78E-36 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 Gene3D G3DSA:2.30.40.10 49 113 5.9E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 Pfam PF01979 Amidohydrolase family 369 465 1.4E-12 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 SUPERFAMILY SSF51338 51 104 4.16E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS03340 59971b9adde6f01721f47da001f38a7a 505 SUPERFAMILY SSF51338 430 460 4.16E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS02840 0714e4ac50625b7979b4a1e6c51b4754 373 Pfam PF02405 Permease MlaE 157 365 3.5E-69 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 SmaCSM2_RS02840 0714e4ac50625b7979b4a1e6c51b4754 373 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 133 366 3.0E-70 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 Gene3D G3DSA:3.30.70.20 73 105 3.1E-13 T 28-03-2018 SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 26.625 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 5.7E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 Gene3D G3DSA:1.10.1060.10 29 72 0.0013 T 28-03-2018 SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 137 2.4E-44 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 SUPERFAMILY SSF54862 36 145 4.02E-25 T 28-03-2018 SmaCSM2_RS15135 840a8fb12ba5dd94da784a9a06d72e07 162 Gene3D G3DSA:3.30.70.20 106 138 2.7E-4 T 28-03-2018 SmaCSM2_RS06480 feb6ed892f1aa725c68bbd893d43fab4 147 SUPERFAMILY SSF54593 13 137 2.55E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS06480 feb6ed892f1aa725c68bbd893d43fab4 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 135 2.3E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS06480 feb6ed892f1aa725c68bbd893d43fab4 147 Gene3D G3DSA:3.10.180.10 9 147 4.8E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 Gene3D G3DSA:1.10.150.240 24 79 3.7E-8 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 193 8.9E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 193 7.0E-20 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 SUPERFAMILY SSF56784 12 221 1.0E-53 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS02465 1068ab03d0f6011dbd6f77d129019882 227 Gene3D G3DSA:3.40.50.1000 80 226 1.6E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS19665 664613927bc89a58ef3b65c08c01da06 106 SUPERFAMILY SSF103481 4 103 2.35E-20 T 28-03-2018 SmaCSM2_RS19665 664613927bc89a58ef3b65c08c01da06 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.0E-28 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SmaCSM2_RS21575 402fb76591b43db48574f39544e02062 489 Pfam PF11855 Protein of unknown function (DUF3375) 11 480 6.4E-152 T 28-03-2018 IPR021804 Protein of unknown function DUF3375 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 TIGRFAM TIGR01224 hutI: imidazolonepropionase 24 397 1.0E-135 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 Gene3D G3DSA:2.30.40.10 2 77 1.0E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 Gene3D G3DSA:3.20.20.140 78 359 6.0E-58 T 28-03-2018 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 Pfam PF01979 Amidohydrolase family 60 376 1.5E-14 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 SUPERFAMILY SSF51338 361 397 1.42E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 SUPERFAMILY SSF51338 3 62 1.42E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 SUPERFAMILY SSF51556 62 359 5.72E-86 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS13690 863b7c9e3d34970e305f3333381c2e23 407 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 399 41.222 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS16250 191222f2a5f6b672a828286b2ae0bb16 79 SUPERFAMILY SSF142921 3 73 2.62E-10 T 28-03-2018 IPR008893 WGR domain SmaCSM2_RS16250 191222f2a5f6b672a828286b2ae0bb16 79 Pfam PF05406 WGR domain 3 73 2.9E-7 T 28-03-2018 IPR008893 WGR domain SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 SUPERFAMILY SSF46785 2 93 1.52E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 Gene3D G3DSA:1.10.10.10 1 94 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 SMART SM00418 8 88 2.0E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 Pfam PF12840 Helix-turn-helix domain 10 69 2.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS12390 a6e800c70684b9dea870309e77fb0af7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 17 227 2.2E-62 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PIRSF PIRSF002764 7 231 3.1E-77 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 64 81 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 38 59 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 204 227 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 112 130 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 143 166 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 87 110 4.9E-53 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14475 99502e3fc2f5afc1e7ac5502f49f22d5 231 Pfam PF03379 CcmB protein 16 228 1.6E-66 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS12730 f71f1d18e8e32329a70534d41394e135 452 Pfam PF13629 Pilus formation protein N terminal region 32 103 2.3E-19 T 28-03-2018 IPR032789 Pilus formation protein, N-terminal SmaCSM2_RS12730 f71f1d18e8e32329a70534d41394e135 452 Pfam PF00263 Bacterial type II and III secretion system protein 250 411 2.6E-45 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 SmaCSM2_RS12730 f71f1d18e8e32329a70534d41394e135 452 PRINTS PR00811 Bacterial general secretion pathway protein D signature 246 270 3.8E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12730 f71f1d18e8e32329a70534d41394e135 452 PRINTS PR00811 Bacterial general secretion pathway protein D signature 375 393 3.8E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS12730 f71f1d18e8e32329a70534d41394e135 452 PRINTS PR00811 Bacterial general secretion pathway protein D signature 398 412 3.8E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 Gene3D G3DSA:1.10.760.10 247 321 0.26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 Gene3D G3DSA:1.10.760.10 97 246 1.9E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 137 217 8.3E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 Pfam PF03239 Iron permease FTR1 family 367 505 2.2E-18 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 Pfam PF03239 Iron permease FTR1 family 509 596 1.1E-8 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 SmaCSM2_RS10950 122fcccbf2832547b3d97943558caa3e 652 SUPERFAMILY SSF46626 118 221 5.3E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS17985 111be08bee12902bbb6828f28ab93463 313 Gene3D G3DSA:3.30.1180.10 171 307 1.4E-21 T 28-03-2018 SmaCSM2_RS17985 111be08bee12902bbb6828f28ab93463 313 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 305 3.5E-36 T 28-03-2018 IPR003797 DegV SmaCSM2_RS17985 111be08bee12902bbb6828f28ab93463 313 Gene3D G3DSA:3.40.50.10170 1 170 1.2E-36 T 28-03-2018 SmaCSM2_RS17985 111be08bee12902bbb6828f28ab93463 313 SUPERFAMILY SSF82549 1 305 2.17E-54 T 28-03-2018 SmaCSM2_RS17985 111be08bee12902bbb6828f28ab93463 313 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 306 4.8E-69 T 28-03-2018 IPR003797 DegV SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 11 147 1.5E-37 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 Gene3D G3DSA:3.40.50.2000 3 175 2.0E-37 T 28-03-2018 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 353 3.4E-38 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 11 361 35.767 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 SUPERFAMILY SSF53756 10 359 4.71E-111 T 28-03-2018 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 9 357 9.9E-106 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03260 9a502198001c67155c0f817fd9a4a1bf 362 Gene3D G3DSA:3.40.50.2000 176 355 1.7E-34 T 28-03-2018 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Pfam PF08245 Mur ligase middle domain 120 299 4.6E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 SUPERFAMILY SSF53244 319 464 6.04E-43 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Gene3D G3DSA:3.90.190.20 321 470 4.9E-34 T 28-03-2018 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Pfam PF01225 Mur ligase family, catalytic domain 18 115 9.8E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 18 466 4.9E-164 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Gene3D G3DSA:3.40.50.720 17 103 7.6E-17 T 28-03-2018 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 15 473 43.021 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 SUPERFAMILY SSF51984 17 102 1.2E-27 T 28-03-2018 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 SUPERFAMILY SSF53623 101 317 1.18E-69 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Gene3D G3DSA:3.40.1190.10 104 320 1.2E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03265 781a99dedae5e38356a75eca8365e964 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 411 2.2E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 131 157 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 95 115 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 189 211 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 160 183 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 27 55 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 218 244 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 PRINTS PR00169 Potassium channel signature 69 92 2.8E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 Gene3D G3DSA:1.20.120.350 32 159 1.8E-26 T 28-03-2018 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 Gene3D G3DSA:1.10.287.70 160 208 1.9E-13 T 28-03-2018 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 Pfam PF00520 Ion transport protein 35 249 1.6E-32 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 Gene3D G3DSA:1.20.5.110 210 246 2.4E-13 T 28-03-2018 SmaCSM2_RS17550 fea87b72ad3100e04952f2a701138e5d 290 SUPERFAMILY SSF81324 29 244 1.5E-52 T 28-03-2018 SmaCSM2_RS21735 368b1b745d4dac548e7986223c7de516 371 Gene3D G3DSA:3.20.20.190 16 368 2.4E-69 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SmaCSM2_RS21735 368b1b745d4dac548e7986223c7de516 371 SUPERFAMILY SSF51695 31 360 9.68E-75 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SmaCSM2_RS21735 368b1b745d4dac548e7986223c7de516 371 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 37 354 8.5E-47 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 3.8E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 SUPERFAMILY SSF46785 6 88 1.14E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 SUPERFAMILY SSF53850 96 295 1.12E-28 T 28-03-2018 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 Gene3D G3DSA:3.40.190.10 93 177 4.1E-10 T 28-03-2018 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 3.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 3.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 3.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 Gene3D G3DSA:1.10.10.10 7 89 3.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 Pfam PF03466 LysR substrate binding domain 96 294 1.4E-27 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS15250 66b933ea7fe33a55d38d546db151df9d 295 Gene3D G3DSA:3.40.190.10 178 265 9.6E-18 T 28-03-2018 SmaCSM2_RS19540 fcb883278a62281761fe13221a5ebb70 414 Gene3D G3DSA:2.40.50.100 61 147 3.1E-17 T 28-03-2018 SmaCSM2_RS19540 fcb883278a62281761fe13221a5ebb70 414 SUPERFAMILY SSF111369 67 303 1.28E-55 T 28-03-2018 SmaCSM2_RS19540 fcb883278a62281761fe13221a5ebb70 414 Gene3D G3DSA:2.40.50.100 179 383 1.5E-5 T 28-03-2018 SmaCSM2_RS19540 fcb883278a62281761fe13221a5ebb70 414 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 298 2.0E-18 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS19540 fcb883278a62281761fe13221a5ebb70 414 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 380 5.2E-80 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 1021 1027 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF52540 413 435 2.19E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF52540 521 600 2.19E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF52540 187 235 2.19E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF52540 278 369 2.19E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Gene3D G3DSA:3.40.50.150 879 1256 4.0E-28 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF52980 21 151 5.9E-10 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Pfam PF02384 N-6 DNA Methylase 859 1034 1.0E-4 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SMART SM00490 513 597 1.6E-5 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Gene3D G3DSA:3.40.50.300 423 612 2.5E-10 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Gene3D G3DSA:3.40.50.300 151 392 2.2E-25 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 916 930 9.1E-7 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 1018 1030 9.1E-7 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 881 897 9.1E-7 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SUPERFAMILY SSF53335 794 1179 9.0E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 SMART SM00487 164 403 3.5E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Gene3D G3DSA:3.40.1350.10 7 150 1.2E-22 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Pfam PF04851 Type III restriction enzyme, res subunit 166 367 1.1E-33 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Pfam PF13156 Restriction endonuclease 35 156 1.4E-46 T 28-03-2018 SmaCSM2_RS09100 609c447a7b18d570bb0d5c4f31104a1a 1634 Pfam PF00271 Helicase conserved C-terminal domain 522 596 1.4E-6 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS05200 4a8b51a7d1d18f0faeaf997018d0a663 341 Gene3D G3DSA:3.90.1200.10 98 338 8.3E-30 T 28-03-2018 SmaCSM2_RS05200 4a8b51a7d1d18f0faeaf997018d0a663 341 Pfam PF01636 Phosphotransferase enzyme family 30 251 6.7E-24 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SmaCSM2_RS05200 4a8b51a7d1d18f0faeaf997018d0a663 341 Gene3D G3DSA:3.30.200.20 7 97 8.9E-23 T 28-03-2018 SmaCSM2_RS05200 4a8b51a7d1d18f0faeaf997018d0a663 341 SUPERFAMILY SSF56112 17 317 3.35E-37 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS13320 d69399e5c4ca6c5e0911493b69d88dcb 174 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 17 160 45.509 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SmaCSM2_RS13320 d69399e5c4ca6c5e0911493b69d88dcb 174 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 112 2.3E-25 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SmaCSM2_RS13320 d69399e5c4ca6c5e0911493b69d88dcb 174 Gene3D G3DSA:3.40.140.10 8 168 4.4E-49 T 28-03-2018 SmaCSM2_RS13320 d69399e5c4ca6c5e0911493b69d88dcb 174 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 64 101 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SmaCSM2_RS13320 d69399e5c4ca6c5e0911493b69d88dcb 174 SUPERFAMILY SSF53927 10 161 5.86E-54 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 Gene3D G3DSA:3.40.50.300 187 305 5.8E-13 T 28-03-2018 SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 Pfam PF01078 Magnesium chelatase, subunit ChlI 188 302 1.2E-51 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 SUPERFAMILY SSF54211 10 165 4.55E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 4.9E-43 T 28-03-2018 SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 302 4.8E-114 T 28-03-2018 IPR004482 Mg chelatase-related protein SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 Gene3D G3DSA:3.30.230.10 3 172 8.3E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS20075 76836d388abfb079b3d2a9894fe04bde 308 SUPERFAMILY SSF52540 188 302 6.25E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 Gene3D G3DSA:1.20.120.220 87 266 1.3E-42 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 SUPERFAMILY SSF81336 87 260 1.96E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 Pfam PF00119 ATP synthase A chain 39 260 2.9E-56 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 ProSitePatterns PS00449 ATP synthase a subunit signature. 196 205 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 PRINTS PR00123 ATP synthase A subunit signature 96 112 5.0E-13 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 PRINTS PR00123 ATP synthase A subunit signature 246 261 5.0E-13 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 PRINTS PR00123 ATP synthase A subunit signature 193 215 5.0E-13 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 Hamap MF_01393 ATP synthase subunit a [atpB]. 12 266 15.134 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18720 171d7f1de3206c2306f7eb2d0f329876 266 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 37 260 1.5E-42 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS17725 d2a9243650b71e8faa6fd4356a76e32c 614 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 590 1.7E-215 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SmaCSM2_RS17725 d2a9243650b71e8faa6fd4356a76e32c 614 Pfam PF01964 Radical SAM ThiC family 139 586 7.5E-201 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SmaCSM2_RS17725 d2a9243650b71e8faa6fd4356a76e32c 614 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 592 56.265 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SmaCSM2_RS17725 d2a9243650b71e8faa6fd4356a76e32c 614 Pfam PF13667 ThiC-associated domain 22 99 8.1E-31 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 Gene3D G3DSA:3.40.50.300 2 23 0.12 T 28-03-2018 SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 Pfam PF03668 P-loop ATPase protein family 11 291 2.9E-90 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 294 37.972 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 SUPERFAMILY SSF52540 11 163 3.38E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 Gene3D G3DSA:3.40.50.300 24 164 8.5E-8 T 28-03-2018 SmaCSM2_RS05080 bdc822fa4c0faabbddd1e7a11acd6430 294 PIRSF PIRSF005052 9 294 5.7E-108 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 Gene3D G3DSA:2.30.30.40 1 60 7.3E-8 T 28-03-2018 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 PIRSF PIRSF034961 1 114 8.8E-41 T 28-03-2018 IPR014593 Uncharacterised conserved protein UCP034961, SH3-2 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 SUPERFAMILY SSF50044 2 60 2.99E-7 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 Pfam PF07653 Variant SH3 domain 3 56 1.6E-9 T 28-03-2018 IPR011511 Variant SH3 domain SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 Gene3D G3DSA:2.30.30.40 61 116 3.0E-12 T 28-03-2018 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 SMART SM00326 61 113 5.7E-5 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 SMART SM00326 1 59 1.3 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS19835 3ca3a5434cb813740b866169191eeb0b 117 SUPERFAMILY SSF50044 62 114 1.71E-9 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 Pfam PF00797 N-acetyltransferase 22 258 4.7E-60 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 PRINTS PR01543 Arylamine N-acetyltransferase signature 70 92 6.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 PRINTS PR01543 Arylamine N-acetyltransferase signature 103 128 6.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 PRINTS PR01543 Arylamine N-acetyltransferase signature 22 45 6.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 PRINTS PR01543 Arylamine N-acetyltransferase signature 46 69 6.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 SUPERFAMILY SSF54001 1 260 2.35E-72 T 28-03-2018 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 Gene3D G3DSA:3.30.2140.10 1 153 1.5E-36 T 28-03-2018 SmaCSM2_RS19260 584e510a8c6481612b71065d674bfa3a 280 Gene3D G3DSA:3.30.2140.10 158 273 3.0E-12 T 28-03-2018 SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Gene3D G3DSA:3.20.20.450 436 689 2.4E-103 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Pfam PF03707 Bacterial signalling protein N terminal repeat 53 111 2.7E-21 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 242 2.1E-10 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Pfam PF03707 Bacterial signalling protein N terminal repeat 116 171 1.9E-16 T 28-03-2018 IPR005330 MHYT domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 SMART SM00052 439 685 1.9E-117 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 SMART SM00267 258 429 8.5E-63 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 SUPERFAMILY SSF141868 446 689 4.18E-91 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 424 1.3E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Gene3D G3DSA:3.30.70.270 263 435 1.6E-59 T 28-03-2018 SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 428 5.9E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 Pfam PF00563 EAL domain 445 680 4.7E-79 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10115 da011c990c6ef87894ad7546d4f7f5df 711 SUPERFAMILY SSF55073 274 429 2.35E-47 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS02180 51159838af366466cbcc728c949b0862 326 Gene3D G3DSA:1.20.1510.10 22 249 8.6E-50 T 28-03-2018 SmaCSM2_RS02180 51159838af366466cbcc728c949b0862 326 Pfam PF01545 Cation efflux family 28 249 7.8E-38 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS02180 51159838af366466cbcc728c949b0862 326 SUPERFAMILY SSF161111 22 153 3.53E-48 T 28-03-2018 SmaCSM2_RS02180 51159838af366466cbcc728c949b0862 326 SUPERFAMILY SSF161111 182 250 3.53E-48 T 28-03-2018 SmaCSM2_RS02180 51159838af366466cbcc728c949b0862 326 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 323 4.3E-64 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS16890 f92c7e74d67441f2fdea660e1a80593e 400 Gene3D G3DSA:3.40.50.1820 13 380 2.7E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16890 f92c7e74d67441f2fdea660e1a80593e 400 PIRSF PIRSF029171 12 386 1.5E-80 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SmaCSM2_RS16890 f92c7e74d67441f2fdea660e1a80593e 400 Pfam PF03583 Secretory lipase 119 305 4.0E-10 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SmaCSM2_RS16890 f92c7e74d67441f2fdea660e1a80593e 400 SUPERFAMILY SSF53474 73 230 2.56E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16890 f92c7e74d67441f2fdea660e1a80593e 400 SUPERFAMILY SSF53474 290 379 2.56E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS19245 f9b492fa4ad1d4c046745bedae569c85 187 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS19245 f9b492fa4ad1d4c046745bedae569c85 187 Gene3D G3DSA:3.40.30.10 31 183 5.3E-31 T 28-03-2018 SmaCSM2_RS19245 f9b492fa4ad1d4c046745bedae569c85 187 SUPERFAMILY SSF52833 46 178 1.71E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS19245 f9b492fa4ad1d4c046745bedae569c85 187 Pfam PF08534 Redoxin 50 179 1.3E-21 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SmaCSM2_RS13670 584db10fe0a0fd62391d5227def13d50 130 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 127 1.4E-40 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system SmaCSM2_RS13670 584db10fe0a0fd62391d5227def13d50 130 Gene3D G3DSA:1.10.1220.10 93 128 3.3E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SmaCSM2_RS13670 584db10fe0a0fd62391d5227def13d50 130 SUPERFAMILY SSF143100 2 64 1.16E-16 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like SmaCSM2_RS13670 584db10fe0a0fd62391d5227def13d50 130 Gene3D G3DSA:3.30.2390.10 1 74 5.9E-18 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like SmaCSM2_RS08930 3c6ba3c3a6cf9d7892ad59b19a65c638 153 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 72 138 8.3E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08930 3c6ba3c3a6cf9d7892ad59b19a65c638 153 Gene3D G3DSA:1.10.760.10 21 142 5.6E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS08930 3c6ba3c3a6cf9d7892ad59b19a65c638 153 SUPERFAMILY SSF46626 74 143 5.3E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS06400 f85fb53b2123e7e0324bf825bb1b2ffc 416 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 358 2.5E-83 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SmaCSM2_RS06400 f85fb53b2123e7e0324bf825bb1b2ffc 416 SUPERFAMILY SSF53649 28 397 5.4E-96 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS06400 f85fb53b2123e7e0324bf825bb1b2ffc 416 Gene3D G3DSA:3.40.720.10 29 416 8.6E-67 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS20120 3cde165c911ea7698e325de356734478 365 Gene3D G3DSA:2.40.160.10 9 365 4.6E-21 T 28-03-2018 SmaCSM2_RS20120 3cde165c911ea7698e325de356734478 365 SUPERFAMILY SSF56935 32 281 5.95E-10 T 28-03-2018 SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 169 9.9E-50 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 SUPERFAMILY SSF46785 7 82 9.68E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 8 171 1.6E-33 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 SUPERFAMILY SSF46785 85 160 1.73E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 Gene3D G3DSA:1.10.10.10 1 84 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14430 8c182587e50d9bf278ecd67bf96c3748 291 Gene3D G3DSA:1.10.10.10 85 177 2.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10685 847ca46ed865d0beb01b216c0c1bde16 208 Pfam PF05857 TraX protein 6 202 4.5E-39 T 28-03-2018 IPR008875 TraX SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 Gene3D G3DSA:3.30.1320.10 1 79 1.1E-33 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 SUPERFAMILY SSF54565 1 79 4.58E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 2.0E-32 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 25.258 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 Pfam PF00886 Ribosomal protein S16 8 68 5.8E-25 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS06065 8db9e80865416c2777e9a6e2e1b53e87 86 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 SUPERFAMILY SSF50182 637 701 1.21E-14 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 Pfam PF00924 Mechanosensitive ion channel 593 791 2.1E-45 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 Pfam PF12607 Protein of unknown function (DUF3772) 132 192 6.6E-17 T 28-03-2018 IPR022249 Domain of unknown function DUF3772 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 SUPERFAMILY SSF82861 550 634 3.79E-13 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 Gene3D G3DSA:3.30.70.100 703 796 2.7E-11 T 28-03-2018 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 SUPERFAMILY SSF82689 704 796 6.8E-12 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SmaCSM2_RS19880 dd4463600c2b30ec474fc093f1556ad8 806 Gene3D G3DSA:2.30.30.60 652 702 8.4E-12 T 28-03-2018 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Pfam PF13721 SecD export protein N-terminal TM region 10 110 4.2E-29 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Pfam PF02355 Protein export membrane protein 446 614 2.1E-20 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 SUPERFAMILY SSF82866 421 620 9.02E-39 T 28-03-2018 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 10 625 48.469 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 356 604 3.7E-66 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Gene3D G3DSA:3.40.50.300 107 316 0.0013 T 28-03-2018 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Pfam PF07549 SecD/SecF GG Motif 123 148 9.3E-8 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 Gene3D G3DSA:1.20.1640.10 391 618 2.9E-32 T 28-03-2018 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 PRINTS PR00702 Acriflavin resistance protein family signature 513 537 5.8E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 PRINTS PR00702 Acriflavin resistance protein family signature 588 611 5.8E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08835 de52b822f0fff7a875223d55ce97ff0b 626 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 130 610 5.9E-128 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 Gene3D G3DSA:3.40.50.150 10 224 1.6E-40 T 28-03-2018 SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 Pfam PF00145 C-5 cytosine-specific DNA methylase 464 522 5.9E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 Pfam PF00145 C-5 cytosine-specific DNA methylase 21 210 1.1E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 83 95 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 SUPERFAMILY SSF53335 19 224 4.71E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 SUPERFAMILY SSF53335 379 526 4.71E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS07750 2c179607d005217ac86f5ef78f4fbb7e 535 Gene3D G3DSA:3.90.120.10 311 510 1.0E-10 T 28-03-2018 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 Pfam PF00108 Thiolase, N-terminal domain 12 282 8.3E-53 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 Pfam PF02803 Thiolase, C-terminal domain 291 431 1.4E-31 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 PIRSF PIRSF000429 6 431 3.2E-102 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 Gene3D G3DSA:3.40.47.10 4 283 3.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 SUPERFAMILY SSF53901 288 431 2.06E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 Gene3D G3DSA:3.40.47.10 284 429 1.1E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 14 430 4.0E-114 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS00685 47313f8e3ab8403542307db80c80172f 431 SUPERFAMILY SSF53901 12 288 2.31E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS12130 43abd97a9d39da1d300c46c6ce48f01f 204 Gene3D G3DSA:3.10.610.10 38 146 4.3E-12 T 28-03-2018 SmaCSM2_RS12130 43abd97a9d39da1d300c46c6ce48f01f 204 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 4.0E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12130 43abd97a9d39da1d300c46c6ce48f01f 204 SUPERFAMILY SSF54523 8 129 1.22E-8 T 28-03-2018 SmaCSM2_RS12130 43abd97a9d39da1d300c46c6ce48f01f 204 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12130 43abd97a9d39da1d300c46c6ce48f01f 204 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 26 8.1E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS20905 fccf29199da8c4073cdb5355d0a52343 390 Gene3D G3DSA:2.70.50.50 28 210 7.5E-61 T 28-03-2018 SmaCSM2_RS20905 fccf29199da8c4073cdb5355d0a52343 390 SUPERFAMILY SSF81296 28 210 1.4E-52 T 28-03-2018 IPR014756 Immunoglobulin E-set SmaCSM2_RS20905 fccf29199da8c4073cdb5355d0a52343 390 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 207 9.1E-44 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 SUPERFAMILY SSF53720 6 487 5.11E-147 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 Gene3D G3DSA:3.40.605.10 2 266 2.5E-89 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 Pfam PF00171 Aldehyde dehydrogenase family 17 480 1.3E-144 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 484 8.4E-225 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 Gene3D G3DSA:3.40.309.10 267 462 1.1E-59 T 28-03-2018 SmaCSM2_RS01180 fedd02e360cdd623a082a9437539d530 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09210 b604e6be1b1b5e92fc261f7f88254297 589 Pfam PF06100 MCRA family 23 520 2.3E-216 T 28-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 SmaCSM2_RS09210 b604e6be1b1b5e92fc261f7f88254297 589 Gene3D G3DSA:3.50.50.60 27 361 6.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS09210 b604e6be1b1b5e92fc261f7f88254297 589 SUPERFAMILY SSF51905 28 256 2.24E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21180 d2a89c2c7ab1716d14964bd023472133 139 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS21180 d2a89c2c7ab1716d14964bd023472133 139 SUPERFAMILY SSF55811 7 126 2.71E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS21180 d2a89c2c7ab1716d14964bd023472133 139 Gene3D G3DSA:3.90.79.10 2 139 1.3E-21 T 28-03-2018 SmaCSM2_RS21180 d2a89c2c7ab1716d14964bd023472133 139 Pfam PF00293 NUDIX domain 9 113 1.4E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 35.305 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 PIRSF PIRSF001456 3 361 7.5E-132 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 9.8E-133 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 Pfam PF01264 Chorismate synthase 10 345 1.2E-130 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 Gene3D G3DSA:3.60.150.10 3 357 7.0E-149 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 SUPERFAMILY SSF103263 4 351 6.93E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS15310 33054fb3b82ed0b98dbbdc873954f66f 367 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SmaCSM2_RS05995 ccbf1c2d3eca4e4667a23b691cc497fd 211 Pfam PF06445 GyrI-like small molecule binding domain 24 197 2.8E-22 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain SmaCSM2_RS05995 ccbf1c2d3eca4e4667a23b691cc497fd 211 Gene3D G3DSA:3.20.80.10 1 201 1.7E-65 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain SmaCSM2_RS05995 ccbf1c2d3eca4e4667a23b691cc497fd 211 SUPERFAMILY SSF55136 124 201 1.91E-9 T 28-03-2018 SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 68 367 4.4E-46 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 Gene3D G3DSA:2.40.50.100 33 117 2.1E-6 T 28-03-2018 SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 SUPERFAMILY SSF111369 74 303 4.84E-25 T 28-03-2018 SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 298 1.9E-32 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 Gene3D G3DSA:1.10.287.470 122 178 2.0E-7 T 28-03-2018 SmaCSM2_RS11950 52b38b3ad5d0c1f51e4ace61e5933669 390 Gene3D G3DSA:2.40.50.100 187 311 2.2E-4 T 28-03-2018 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 PIRSF PIRSF002161 1 180 1.6E-65 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 SUPERFAMILY SSF55282 4 180 1.46E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 Pfam PF00281 Ribosomal protein L5 25 81 2.5E-27 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.293 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 9.2E-40 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04050 95cde0388cbecd1a0a55674ca20cbf5a 180 Gene3D G3DSA:3.30.1440.10 2 180 1.4E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 SMART SM00448 3 123 2.4E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 Pfam PF00563 EAL domain 146 379 6.9E-57 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 Gene3D G3DSA:3.20.20.450 140 399 5.6E-68 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 Gene3D G3DSA:3.40.50.2300 1 139 1.7E-20 T 28-03-2018 SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 Pfam PF00072 Response regulator receiver domain 5 115 9.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 SUPERFAMILY SSF141868 146 391 3.27E-63 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 SUPERFAMILY SSF52172 4 128 1.71E-19 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS03870 9207c5b1d7d49001fbf19257c8f3c39c 406 SMART SM00052 137 385 1.4E-50 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS16040 6fa51246371635b9e52bb5ec51c130b5 549 SUPERFAMILY SSF53649 242 535 4.49E-19 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS16040 6fa51246371635b9e52bb5ec51c130b5 549 Pfam PF00884 Sulfatase 246 531 1.6E-48 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SmaCSM2_RS16040 6fa51246371635b9e52bb5ec51c130b5 549 Gene3D G3DSA:3.40.720.10 233 536 4.0E-19 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS16040 6fa51246371635b9e52bb5ec51c130b5 549 Pfam PF08019 Domain of unknown function (DUF1705) 69 212 5.3E-46 T 28-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 SmaCSM2_RS18975 f3bbc88a806438ec9c6652e237ab7f5b 174 SUPERFAMILY SSF52540 4 163 2.63E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18975 f3bbc88a806438ec9c6652e237ab7f5b 174 Pfam PF13671 AAA domain 5 140 2.4E-13 T 28-03-2018 SmaCSM2_RS18975 f3bbc88a806438ec9c6652e237ab7f5b 174 Gene3D G3DSA:3.40.50.300 1 156 2.2E-13 T 28-03-2018 SmaCSM2_RS15450 f47c43dd1abaa8379e33e18abdf59ca2 164 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 118 2.9E-45 T 28-03-2018 IPR028973 PhnB-like SmaCSM2_RS15450 f47c43dd1abaa8379e33e18abdf59ca2 164 Gene3D G3DSA:3.10.180.10 1 130 4.8E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS15450 f47c43dd1abaa8379e33e18abdf59ca2 164 PIRSF PIRSF021700 1 159 5.3E-65 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase SmaCSM2_RS15450 f47c43dd1abaa8379e33e18abdf59ca2 164 SUPERFAMILY SSF54593 4 157 1.24E-46 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS01430 eba1ccd42a748cce10e465abe37f8b4d 301 SUPERFAMILY SSF103481 53 153 1.57E-11 T 28-03-2018 SmaCSM2_RS01430 eba1ccd42a748cce10e465abe37f8b4d 301 SUPERFAMILY SSF103481 197 298 1.06E-15 T 28-03-2018 SmaCSM2_RS01430 eba1ccd42a748cce10e465abe37f8b4d 301 Pfam PF00892 EamA-like transporter family 18 150 1.2E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS01430 eba1ccd42a748cce10e465abe37f8b4d 301 Pfam PF00892 EamA-like transporter family 160 294 2.9E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 28-03-2018 IPR019844 Cold-shock conserved site SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 SMART SM00357 6 69 8.1E-28 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 PRINTS PR00050 Cold shock protein signature 7 22 4.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 PRINTS PR00050 Cold shock protein signature 27 36 4.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 PRINTS PR00050 Cold shock protein signature 42 60 4.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 3.3E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 PIRSF PIRSF002599 1 69 1.1E-21 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 SUPERFAMILY SSF50249 2 68 2.14E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08880 9bd0369f801b444159a91368aaead3a8 69 Gene3D G3DSA:2.40.50.140 1 69 7.9E-27 T 28-03-2018 SmaCSM2_RS05865 fe1219f2046f534cc5ae75ea5f928661 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 227 8.3E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS05865 fe1219f2046f534cc5ae75ea5f928661 258 SUPERFAMILY SSF52096 9 255 1.76E-50 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS05865 fe1219f2046f534cc5ae75ea5f928661 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SmaCSM2_RS05865 fe1219f2046f534cc5ae75ea5f928661 258 Gene3D G3DSA:3.90.226.10 1 256 5.2E-49 T 28-03-2018 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Gene3D G3DSA:3.30.70.610 265 347 1.0E-14 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Gene3D G3DSA:3.30.70.610 349 427 7.5E-26 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 PIRSF PIRSF000101 1 562 4.4E-264 T 28-03-2018 IPR012256 D-lactate dehydrogenase GO:0004457|GO:0005887|GO:0006089|GO:0050660|GO:0051287 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Pfam PF01565 FAD binding domain 42 180 5.0E-8 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Gene3D G3DSA:3.30.1370.20 428 511 2.7E-39 T 28-03-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Gene3D G3DSA:3.30.465.10 102 264 2.9E-76 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 SUPERFAMILY SSF55103 272 560 2.18E-107 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 SUPERFAMILY SSF56176 5 267 5.14E-67 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Pfam PF09330 D-lactate dehydrogenase, membrane binding 273 560 2.7E-136 T 28-03-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 SmaCSM2_RS12900 278050d2428a0321bf2a6a0ecafce6d9 568 Gene3D G3DSA:3.30.43.10 2 94 1.4E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS10720 137933a3588eb9be0bfa3a93ad0282eb 116 Gene3D G3DSA:1.10.287.910 16 68 4.5E-19 T 28-03-2018 SmaCSM2_RS10720 137933a3588eb9be0bfa3a93ad0282eb 116 Pfam PF02411 MerT mercuric transport protein 1 116 6.3E-62 T 28-03-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 SmaCSM2_RS05330 8692a581a576158dc8c79e51d7d4b15f 155 SMART SM00317 3 128 1.8E-31 T 28-03-2018 IPR001214 SET domain GO:0005515 SmaCSM2_RS05330 8692a581a576158dc8c79e51d7d4b15f 155 Pfam PF00856 SET domain 14 122 1.6E-19 T 28-03-2018 IPR001214 SET domain GO:0005515 SmaCSM2_RS05330 8692a581a576158dc8c79e51d7d4b15f 155 SUPERFAMILY SSF82199 3 148 3.66E-42 T 28-03-2018 SmaCSM2_RS05330 8692a581a576158dc8c79e51d7d4b15f 155 Gene3D G3DSA:2.170.270.10 1 151 1.6E-43 T 28-03-2018 SmaCSM2_RS17030 bf5856009b08fcd3c2a62127e3662fdf 264 SUPERFAMILY SSF110399 8 250 1.12E-89 T 28-03-2018 SmaCSM2_RS17030 bf5856009b08fcd3c2a62127e3662fdf 264 Hamap MF_00443 Thiazole synthase [thiG]. 9 264 43.097 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SmaCSM2_RS17030 bf5856009b08fcd3c2a62127e3662fdf 264 Pfam PF05690 Thiazole biosynthesis protein ThiG 12 258 6.4E-113 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SmaCSM2_RS17030 bf5856009b08fcd3c2a62127e3662fdf 264 Gene3D G3DSA:3.20.20.70 7 264 1.2E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 SMART SM00388 264 332 1.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 Gene3D G3DSA:3.30.450.20 25 159 6.9E-7 T 28-03-2018 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 383 484 9.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 SUPERFAMILY SSF55874 323 484 3.8E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 Gene3D G3DSA:1.10.287.130 254 328 2.6E-13 T 28-03-2018 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 SUPERFAMILY SSF47384 247 333 4.12E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 Gene3D G3DSA:3.30.565.10 336 488 7.9E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 Pfam PF00512 His Kinase A (phospho-acceptor) domain 265 332 4.1E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 SMART SM00387 378 486 7.1E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 9.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 9.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS02565 7c57a4cad6ff48f2e7c0a68f609b01d4 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 9.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 Gene3D G3DSA:3.40.50.720 1 209 2.2E-65 T 28-03-2018 SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 5.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 5.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 169 0.001 T 28-03-2018 SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 Pfam PF00106 short chain dehydrogenase 7 208 1.7E-54 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS08615 fca94478cef6872bb56f9d777aececb6 245 SUPERFAMILY SSF51735 3 226 6.99E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18490 a5c7276bfbc8bcf8eb899f1091c9d606 90 Pfam PF13627 Prokaryotic lipoprotein-attachment site 13 33 2.3E-7 T 28-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 Gene3D G3DSA:3.40.190.10 90 180 7.2E-20 T 28-03-2018 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 SUPERFAMILY SSF53850 91 297 8.39E-36 T 28-03-2018 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 Gene3D G3DSA:3.40.190.10 181 267 2.1E-17 T 28-03-2018 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 SUPERFAMILY SSF46785 1 88 5.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 Gene3D G3DSA:1.10.10.10 1 84 5.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 2.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS17125 8913a6df77657b4f82f36a7b79e5f3e6 327 Pfam PF03466 LysR substrate binding domain 89 291 1.8E-39 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS14355 685f716bef4a27a3111306f1e73f4621 138 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 43 119 2.8E-16 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS14355 685f716bef4a27a3111306f1e73f4621 138 Gene3D G3DSA:3.30.1150.10 20 127 1.1E-18 T 28-03-2018 SmaCSM2_RS14355 685f716bef4a27a3111306f1e73f4621 138 SUPERFAMILY SSF74653 37 117 3.66E-18 T 28-03-2018 SmaCSM2_RS14355 685f716bef4a27a3111306f1e73f4621 138 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 41 118 5.7E-19 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 23 718 7.2E-138 T 28-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 Gene3D G3DSA:2.40.170.20 158 717 3.4E-79 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 Pfam PF07715 TonB-dependent Receptor Plug Domain 37 146 3.1E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 SUPERFAMILY SSF56935 14 718 1.56E-124 T 28-03-2018 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 Pfam PF00593 TonB dependent receptor 243 716 7.6E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 23 718 3.4E-119 T 28-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 SmaCSM2_RS03440 f923453aa8c02d26b566465551505f91 718 Gene3D G3DSA:2.170.130.10 13 157 6.8E-31 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 200 3.8E-41 T 28-03-2018 IPR003111 Lon, substrate-binding domain SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PIRSF PIRSF001174 1 787 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 SUPERFAMILY SSF52540 314 600 8.99E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 TIGRFAM TIGR00763 lon: endopeptidase La 12 784 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 SMART SM00464 10 203 2.1E-69 T 28-03-2018 IPR003111 Lon, substrate-binding domain SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 SUPERFAMILY SSF88697 10 202 1.66E-46 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 686 705 1.2E-53 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 357 376 1.2E-53 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 608 624 1.2E-53 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 716 735 1.2E-53 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 739 757 1.2E-53 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Gene3D G3DSA:3.30.230.10 598 785 2.3E-65 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Gene3D G3DSA:3.40.50.300 303 505 1.2E-31 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 583 785 1.0E-93 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Hamap MF_01973 Lon protease [lon]. 11 785 71.666 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 353 489 7.8E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Gene3D G3DSA:2.30.130.40 1 118 5.0E-32 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 SMART SM00382 349 495 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Gene3D G3DSA:1.10.8.60 506 597 5.2E-33 T 28-03-2018 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 689 697 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 SUPERFAMILY SSF54211 608 783 1.44E-56 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS04430 f828d4d55bb20cca5c809d8316974d75 816 Gene3D G3DSA:1.10.4060.10 123 212 2.8E-27 T 28-03-2018 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 Pfam PF01339 CheB methylesterase 173 351 3.7E-58 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 Pfam PF00072 Response regulator receiver domain 11 113 1.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 SUPERFAMILY SSF52738 168 355 6.54E-70 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 SMART SM00448 9 132 8.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 Gene3D G3DSA:3.40.50.180 162 357 5.9E-75 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 Gene3D G3DSA:3.40.50.2300 2 156 1.1E-28 T 28-03-2018 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 SUPERFAMILY SSF52172 8 113 1.12E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 PIRSF PIRSF000876 6 357 1.2E-135 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09985 3ad9f41e3d12d1ec2e1e860a5e7ed556 357 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 9 356 40.923 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 Pfam PF12390 Selenocysteine synthase N terminal 13 50 4.1E-6 T 28-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 Gene3D G3DSA:3.40.640.10 103 359 2.8E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 SUPERFAMILY SSF53383 87 353 1.39E-41 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 474 225.914 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 13 468 1.4E-172 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 SmaCSM2_RS17410 c7697a794594541631fc178c7d9d42ae 474 Pfam PF03841 L-seryl-tRNA selenium transferase 92 457 4.5E-156 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 SmaCSM2_RS14715 f8c87b989e6547388d5e5664924cbe63 256 PIRSF PIRSF004808 6 250 2.4E-71 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SmaCSM2_RS14715 f8c87b989e6547388d5e5664924cbe63 256 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 8 244 1.7E-66 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SmaCSM2_RS14715 f8c87b989e6547388d5e5664924cbe63 256 SUPERFAMILY SSF75217 8 170 7.85E-36 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS14715 f8c87b989e6547388d5e5664924cbe63 256 Pfam PF00588 SpoU rRNA Methylase family 10 160 1.9E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS14715 f8c87b989e6547388d5e5664924cbe63 256 Gene3D G3DSA:3.40.1280.10 1 170 1.6E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 SMART SM00257 487 532 6.5E-8 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 Pfam PF01464 Transglycosylase SLT domain 199 306 1.4E-21 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 SUPERFAMILY SSF53955 196 342 8.78E-34 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 Gene3D G3DSA:3.10.350.10 474 536 1.9E-9 T 28-03-2018 SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 SUPERFAMILY SSF54106 486 531 4.45E-7 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 Gene3D G3DSA:1.10.530.10 175 346 1.3E-32 T 28-03-2018 SmaCSM2_RS15335 6df0c021b91e814df1bb40d601d5023b 536 Pfam PF01476 LysM domain 488 531 5.1E-11 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 89 182 2.9E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 714 731 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 Gene3D G3DSA:2.40.170.20 204 731 2.4E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 90 731 9.3E-115 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 SUPERFAMILY SSF56935 45 731 6.54E-97 T 28-03-2018 SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 Pfam PF00593 TonB dependent receptor 293 729 1.6E-29 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11720 89e9c983912213978c7aab3a93581cae 731 Gene3D G3DSA:2.170.130.10 45 203 2.2E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS13190 d8539b95d985ba3cea2851d62deee6ca 464 SUPERFAMILY SSF56954 6 462 3.01E-99 T 28-03-2018 SmaCSM2_RS13190 d8539b95d985ba3cea2851d62deee6ca 464 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 461 1.4E-111 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS13190 d8539b95d985ba3cea2851d62deee6ca 464 Pfam PF02321 Outer membrane efflux protein 275 459 1.2E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS13190 d8539b95d985ba3cea2851d62deee6ca 464 Pfam PF02321 Outer membrane efflux protein 62 253 2.4E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS13190 d8539b95d985ba3cea2851d62deee6ca 464 Gene3D G3DSA:1.20.1600.10 20 464 4.7E-95 T 28-03-2018 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 Pfam PF00005 ABC transporter 348 506 4.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 287 2.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 SUPERFAMILY SSF161098 69 282 5.36E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 SMART SM00382 357 554 2.9E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 SUPERFAMILY SSF52540 334 576 1.39E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 Gene3D G3DSA:3.40.50.300 331 580 8.4E-77 T 28-03-2018 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 68 182 1.8E-13 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS09280 6f7fd844274656dfdd574be13fe02449 581 Gene3D G3DSA:1.10.3720.10 26 293 7.7E-40 T 28-03-2018 SmaCSM2_RS07380 2fdcbdf4a2a7c685d3de3dcd2279a074 304 Pfam PF13533 Biotin-lipoyl like 59 105 9.7E-11 T 28-03-2018 SmaCSM2_RS07380 2fdcbdf4a2a7c685d3de3dcd2279a074 304 Pfam PF13437 HlyD family secretion protein 182 264 9.1E-8 T 28-03-2018 SmaCSM2_RS07380 2fdcbdf4a2a7c685d3de3dcd2279a074 304 Gene3D G3DSA:1.20.1600.10 54 261 5.7E-16 T 28-03-2018 SmaCSM2_RS07380 2fdcbdf4a2a7c685d3de3dcd2279a074 304 SUPERFAMILY SSF111369 59 223 2.22E-12 T 28-03-2018 SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 SMART SM00267 283 456 9.6E-62 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 Gene3D G3DSA:1.10.490.10 16 166 2.6E-15 T 28-03-2018 SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 SUPERFAMILY SSF46458 38 155 2.45E-16 T 28-03-2018 IPR009050 Globin-like SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 Pfam PF00990 Diguanylate cyclase, GGDEF domain 297 452 1.9E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 Gene3D G3DSA:3.30.70.270 291 464 2.8E-54 T 28-03-2018 SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 295 456 4.8E-52 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 SUPERFAMILY SSF55073 300 457 1.49E-48 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06280 be5b6512f81f1acb3cc70d878a2d2d22 471 Pfam PF11563 Protoglobin 30 165 1.5E-10 T 28-03-2018 SmaCSM2_RS14215 120175fd913eea600f0ad6da981c2cf4 144 Pfam PF01322 Cytochrome C' 95 144 1.4E-5 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 SmaCSM2_RS14215 120175fd913eea600f0ad6da981c2cf4 144 SUPERFAMILY SSF47175 47 144 1.77E-13 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 SmaCSM2_RS14215 120175fd913eea600f0ad6da981c2cf4 144 Gene3D G3DSA:1.20.120.10 35 144 2.1E-10 T 28-03-2018 SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 Gene3D G3DSA:1.10.10.10 3 87 7.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 Gene3D G3DSA:3.40.190.10 176 262 1.6E-27 T 28-03-2018 SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 Pfam PF03466 LysR substrate binding domain 90 291 2.4E-44 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 SUPERFAMILY SSF53850 90 294 7.78E-46 T 28-03-2018 SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 SUPERFAMILY SSF46785 7 112 3.27E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16410 28a4426c66bca09283c554b44c624bc2 297 Gene3D G3DSA:3.40.190.10 89 175 2.2E-13 T 28-03-2018 SmaCSM2_RS01330 635eac4353980156864b80dd167ea4bb 249 SUPERFAMILY SSF55486 32 241 3.0E-32 T 28-03-2018 SmaCSM2_RS01330 635eac4353980156864b80dd167ea4bb 249 Gene3D G3DSA:3.40.390.10 93 244 6.5E-24 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS01330 635eac4353980156864b80dd167ea4bb 249 Pfam PF06167 Glucose-regulated metallo-peptidase M90 9 240 9.4E-78 T 28-03-2018 IPR010384 MtfA family SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 PIRSF PIRSF003101 1 411 7.3E-152 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 4.4E-28 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 3.2E-160 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 SMART SM00842 10 197 3.1E-103 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 SUPERFAMILY SSF53067 200 378 2.59E-46 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Pfam PF14450 Cell division protein FtsA 11 195 5.0E-11 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Pfam PF14450 Cell division protein FtsA 208 375 4.1E-24 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Gene3D G3DSA:3.30.420.40 1 199 3.7E-39 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 411 30.664 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Gene3D G3DSA:3.30.420.40 258 353 7.1E-19 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 Gene3D G3DSA:3.30.420.40 200 257 5.6E-8 T 28-03-2018 SmaCSM2_RS03280 b74756f0e6c8c34ae65bb8dbb2503328 411 SUPERFAMILY SSF53067 9 198 1.18E-60 T 28-03-2018 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 Pfam PF01431 Peptidase family M13 491 694 4.0E-68 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 Gene3D G3DSA:3.40.390.10 58 308 5.5E-10 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 Gene3D G3DSA:3.40.390.10 360 697 6.4E-110 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 SUPERFAMILY SSF55486 53 697 3.04E-208 T 28-03-2018 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 593 604 8.2E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 501 513 8.2E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 483 495 8.2E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 522 538 8.2E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS06310 9d3bd82c23fc325f341e008c3badb419 697 Pfam PF05649 Peptidase family M13 63 439 5.6E-96 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SmaCSM2_RS20920 20363026fb796aa133e6efc25639f7e9 322 SUPERFAMILY SSF52540 14 244 2.3E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20920 20363026fb796aa133e6efc25639f7e9 322 Gene3D G3DSA:3.40.50.300 14 270 2.7E-65 T 28-03-2018 SmaCSM2_RS20920 20363026fb796aa133e6efc25639f7e9 322 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS20920 20363026fb796aa133e6efc25639f7e9 322 SMART SM00382 43 225 5.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS20920 20363026fb796aa133e6efc25639f7e9 322 Pfam PF00005 ABC transporter 34 178 4.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 Pfam PF07729 FCD domain 88 210 8.3E-27 T 28-03-2018 IPR011711 GntR, C-terminal SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 7.5E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 SMART SM00895 88 212 1.7E-18 T 28-03-2018 IPR011711 GntR, C-terminal SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 9.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 9.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 SUPERFAMILY SSF46785 10 82 1.01E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 SUPERFAMILY SSF48008 84 217 8.37E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 SMART SM00345 20 78 3.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 Gene3D G3DSA:1.10.10.10 2 80 4.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05665 664609bf80bc0bfa3cbc799e8315bff8 239 Gene3D G3DSA:1.20.120.530 82 224 6.1E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 SUPERFAMILY SSF46955 1 125 3.0E-36 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 Gene3D G3DSA:1.10.1660.10 1 56 1.6E-25 T 28-03-2018 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 SMART SM00422 1 70 1.4E-32 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 Pfam PF13411 MerR HTH family regulatory protein 1 67 8.9E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS13100 197574198d1da4f21d392ad27c296678 132 Gene3D G3DSA:1.10.1660.10 57 132 5.0E-21 T 28-03-2018 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 Gene3D G3DSA:2.40.50.100 20 85 1.4E-28 T 28-03-2018 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 SUPERFAMILY SSF110324 2 81 1.53E-33 T 28-03-2018 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 Pfam PF01016 Ribosomal L27 protein 2 82 3.8E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.028 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 8.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 4.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS05895 439c554eacaefcf2cdbcd8ad667d72b7 87 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS16145 294b16a03b165aa0129398f2abe7cee6 123 Gene3D G3DSA:3.40.50.2300 1 123 3.8E-37 T 28-03-2018 SmaCSM2_RS16145 294b16a03b165aa0129398f2abe7cee6 123 Pfam PF00072 Response regulator receiver domain 4 115 7.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16145 294b16a03b165aa0129398f2abe7cee6 123 SMART SM00448 2 115 1.1E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16145 294b16a03b165aa0129398f2abe7cee6 123 SUPERFAMILY SSF52172 1 120 1.57E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 Pfam PF03466 LysR substrate binding domain 90 293 1.2E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 Gene3D G3DSA:1.10.10.10 1 85 4.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 SUPERFAMILY SSF53850 90 297 6.52E-42 T 28-03-2018 SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 Gene3D G3DSA:3.40.190.10 93 177 1.6E-18 T 28-03-2018 SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 Gene3D G3DSA:3.40.190.10 178 263 4.1E-24 T 28-03-2018 SmaCSM2_RS11905 e154e35d57186e4c8f35ce643a7901c9 300 SUPERFAMILY SSF46785 4 112 4.86E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 Pfam PF00230 Major intrinsic protein 5 232 3.0E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 SUPERFAMILY SSF81338 5 235 2.88E-63 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 232 1.5E-55 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 Gene3D G3DSA:1.20.1080.10 1 239 7.5E-64 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 Hamap MF_01146 Aquaporin Z [aqpZ]. 4 239 33.377 T 28-03-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 ProSitePatterns PS00221 MIP family signature. 67 75 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 49 73 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 176 198 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 5 24 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 146 164 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 215 235 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS15985 fb33b805dc2986f2c5e996b0f401cc10 239 PRINTS PR00783 Major intrinsic protein family signature 86 105 8.3E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SmaCSM2_RS18750 ed0b79487eacdce2c465bc98dcb55441 211 SUPERFAMILY SSF56925 41 211 6.02E-20 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS18750 ed0b79487eacdce2c465bc98dcb55441 211 Pfam PF03922 OmpW family 59 211 4.8E-38 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 SmaCSM2_RS18750 ed0b79487eacdce2c465bc98dcb55441 211 Gene3D G3DSA:2.40.160.20 19 211 2.1E-24 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 252 2.1E-91 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 Gene3D G3DSA:3.60.15.10 1 252 1.1E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 252 39.252 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 SMART SM00849 12 164 3.9E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 SUPERFAMILY SSF56281 1 253 6.55E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 165 252 1.4E-22 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 PIRSF PIRSF005457 1 252 3.1E-86 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 SmaCSM2_RS04475 f06606023c4e5b5e73d68a5c003f8798 254 Pfam PF00753 Metallo-beta-lactamase superfamily 15 164 6.5E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS18655 03698c039a51ff72f9400e697313dd08 404 Pfam PF12704 MacB-like periplasmic core domain 43 244 1.8E-9 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS18655 03698c039a51ff72f9400e697313dd08 404 Pfam PF02687 FtsX-like permease family 311 380 2.4E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS12945 ff084d1b2c1d2c6a7f4788a60035fbb5 452 Gene3D G3DSA:1.20.1250.20 245 450 1.8E-19 T 28-03-2018 SmaCSM2_RS12945 ff084d1b2c1d2c6a7f4788a60035fbb5 452 Pfam PF07690 Major Facilitator Superfamily 13 400 1.2E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS12945 ff084d1b2c1d2c6a7f4788a60035fbb5 452 SUPERFAMILY SSF103473 5 189 6.15E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12945 ff084d1b2c1d2c6a7f4788a60035fbb5 452 SUPERFAMILY SSF103473 241 445 6.15E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12945 ff084d1b2c1d2c6a7f4788a60035fbb5 452 Gene3D G3DSA:1.20.1250.20 5 195 1.5E-24 T 28-03-2018 SmaCSM2_RS12510 f8c69fd41801de5325980e0efe41f7e9 397 Gene3D G3DSA:3.60.120.10 23 387 2.4E-92 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS12510 f8c69fd41801de5325980e0efe41f7e9 397 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 109 384 4.1E-82 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 SmaCSM2_RS12510 f8c69fd41801de5325980e0efe41f7e9 397 SUPERFAMILY SSF56322 55 386 8.11E-87 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SmaCSM2_RS12510 f8c69fd41801de5325980e0efe41f7e9 397 Pfam PF00425 chorismate binding enzyme 115 376 3.9E-72 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SmaCSM2_RS13260 5a2d3a041772ffd4347245c898e4aafa 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 61 83 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS13260 5a2d3a041772ffd4347245c898e4aafa 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 83 1.4E-12 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 181 2.9E-4 T 28-03-2018 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 5.1E-49 T 28-03-2018 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 202 221 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 98 118 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 78 95 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 228 247 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 163 186 2.1E-46 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 Gene3D G3DSA:3.40.50.720 1 251 4.0E-65 T 28-03-2018 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 250 5.0E-97 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SmaCSM2_RS12485 dd094cabb482f5070a72c856c4a3d954 252 SUPERFAMILY SSF51735 7 250 1.2E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 Gene3D G3DSA:1.10.260.40 38 64 7.1E-14 T 28-03-2018 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 SUPERFAMILY SSF46689 2 86 2.21E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 Gene3D G3DSA:1.10.357.10 65 194 3.5E-14 T 28-03-2018 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.1E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 Gene3D G3DSA:1.10.10.60 1 37 5.6E-17 T 28-03-2018 SmaCSM2_RS02330 459ec10f07e510233c6afa3105fafaf4 195 SUPERFAMILY SSF48498 90 192 6.67E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS14310 99d75073a7bf2656e6b15d60cf284fb9 208 SUPERFAMILY SSF144091 5 187 1.18E-32 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS14310 99d75073a7bf2656e6b15d60cf284fb9 208 Pfam PF01694 Rhomboid family 38 186 3.1E-24 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS14310 99d75073a7bf2656e6b15d60cf284fb9 208 Gene3D G3DSA:1.20.1540.10 1 189 6.3E-34 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS19760 10c365b9d2bc336297ea97032586efbf 168 PIRSF PIRSF019239 8 168 1.4E-41 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS19760 10c365b9d2bc336297ea97032586efbf 168 Pfam PF01899 Na+/H+ ion antiporter subunit 19 166 6.1E-41 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS08300 10fb6efe800154af24ffbd5613fdfe47 159 Pfam PF00578 AhpC/TSA family 19 135 4.4E-30 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS08300 10fb6efe800154af24ffbd5613fdfe47 159 SUPERFAMILY SSF52833 20 157 4.59E-45 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS08300 10fb6efe800154af24ffbd5613fdfe47 159 Gene3D G3DSA:3.40.30.10 1 158 7.8E-31 T 28-03-2018 SmaCSM2_RS08300 10fb6efe800154af24ffbd5613fdfe47 159 PIRSF PIRSF000239 8 159 3.1E-25 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 SMART SM00670 6 145 6.0E-9 T 28-03-2018 IPR002716 PIN domain SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 Pfam PF13638 PIN domain 8 158 1.0E-38 T 28-03-2018 IPR002716 PIN domain SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 SUPERFAMILY SSF88723 108 158 7.85E-11 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 SUPERFAMILY SSF88723 7 67 7.85E-11 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 Pfam PF02562 PhoH-like protein 254 457 2.8E-55 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 Gene3D G3DSA:3.40.50.300 259 461 2.7E-20 T 28-03-2018 SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 Gene3D G3DSA:3.40.50.1010 5 258 1.1E-39 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 SUPERFAMILY SSF52540 131 189 4.37E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08295 a97c6905b6371d98e22277dafa5c2050 466 SUPERFAMILY SSF52540 253 445 4.37E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 457 2.4E-67 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 SUPERFAMILY SSF55103 227 459 1.6E-62 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 Gene3D G3DSA:1.10.45.10 418 457 9.1E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 Pfam PF01565 FAD binding domain 43 182 9.5E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 Gene3D G3DSA:3.30.43.10 2 95 1.1E-22 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 SUPERFAMILY SSF56176 8 219 4.67E-69 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS03180 0c6d8d26b35745771cf37142ba6d3954 461 Gene3D G3DSA:3.30.465.10 96 241 1.2E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 Gene3D G3DSA:2.40.128.130 702 1008 8.0E-34 T 28-03-2018 SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 SUPERFAMILY SSF51126 184 590 2.32E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 Gene3D G3DSA:2.160.20.20 34 591 3.6E-43 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 SMART SM00869 731 992 4.9E-31 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 473 1008 6.2E-63 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 Pfam PF03797 Autotransporter beta-domain 734 979 8.5E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS18205 cc0c412c46b74f4a1de272524fe02c17 1008 SUPERFAMILY SSF103515 712 1008 3.53E-33 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 Gene3D G3DSA:1.10.10.10 62 135 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 Gene3D G3DSA:3.40.640.10 176 392 2.9E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 SMART SM00345 69 128 3.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 Pfam PF00392 Bacterial regulatory proteins, gntR family 66 128 3.3E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 SUPERFAMILY SSF53383 134 494 1.69E-62 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 Gene3D G3DSA:3.90.1150.10 393 497 1.3E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 SUPERFAMILY SSF46785 61 132 2.73E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20450 29e3331f1326eff826643741421a4f58 504 Pfam PF00155 Aminotransferase class I and II 137 390 5.7E-10 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 Gene3D G3DSA:3.40.50.300 110 350 2.2E-43 T 28-03-2018 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 4 604 2.4E-171 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 SUPERFAMILY SSF52540 4 333 8.19E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 Gene3D G3DSA:3.40.50.300 375 593 1.8E-27 T 28-03-2018 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 Pfam PF13538 UvrD-like helicase C-terminal domain 533 579 1.0E-12 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 Pfam PF13604 AAA domain 154 326 1.7E-29 T 28-03-2018 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 13 602 46.778 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 SUPERFAMILY SSF52540 439 603 3.64E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 SUPERFAMILY SSF52540 356 387 3.64E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21615 bf61a19b96e59d72a4530589cb9d41c8 626 SUPERFAMILY SSF52540 289 329 3.64E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 5.4E-258 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Gene3D G3DSA:3.40.50.10490 462 610 1.9E-51 T 28-03-2018 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 SUPERFAMILY SSF53697 247 612 2.23E-109 T 28-03-2018 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Gene3D G3DSA:3.40.50.10490 241 461 2.1E-56 T 28-03-2018 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Pfam PF01380 SIS domain 466 594 1.5E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Pfam PF01380 SIS domain 298 419 6.3E-28 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 39.375 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Gene3D G3DSA:3.60.20.10 2 240 3.1E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 SUPERFAMILY SSF56235 2 236 1.12E-70 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS18635 fc87b2e3ab817521356ab5c2a53c0059 612 Pfam PF13522 Glutamine amidotransferase domain 64 189 2.8E-21 T 28-03-2018 SmaCSM2_RS15470 7ed93031fb44838bc1195f5dd6d4dbe1 306 Pfam PF00892 EamA-like transporter family 19 152 2.1E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS15470 7ed93031fb44838bc1195f5dd6d4dbe1 306 Pfam PF00892 EamA-like transporter family 167 302 1.6E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS15470 7ed93031fb44838bc1195f5dd6d4dbe1 306 SUPERFAMILY SSF103481 54 156 1.83E-13 T 28-03-2018 SmaCSM2_RS15470 7ed93031fb44838bc1195f5dd6d4dbe1 306 SUPERFAMILY SSF103481 217 304 1.22E-13 T 28-03-2018 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 Gene3D G3DSA:3.20.20.70 2 210 1.9E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 Pfam PF01081 KDPG and KHG aldolase 10 203 8.2E-68 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 207 9.4E-75 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS00235 3fcf072afc8e79f12e7b2f460d388d8a 212 SUPERFAMILY SSF51569 9 207 7.14E-65 T 28-03-2018 SmaCSM2_RS17590 2895709898e65bfb1f9b755323786ae3 664 Pfam PF01569 PAP2 superfamily 357 436 8.0E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS17590 2895709898e65bfb1f9b755323786ae3 664 Pfam PF14067 LssY C-terminus 498 619 1.9E-12 T 28-03-2018 IPR025902 LssY-like C-terminal domain SmaCSM2_RS17590 2895709898e65bfb1f9b755323786ae3 664 Gene3D G3DSA:1.20.144.10 276 429 3.2E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS17590 2895709898e65bfb1f9b755323786ae3 664 SUPERFAMILY SSF48317 245 441 1.16E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS17590 2895709898e65bfb1f9b755323786ae3 664 Pfam PF09335 SNARE associated Golgi protein 40 163 2.7E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 32 9.2E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 1.8E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 SUPERFAMILY SSF54523 13 124 1.88E-25 T 28-03-2018 SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 2.1E-11 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 2.1E-11 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 Gene3D G3DSA:3.30.700.10 13 133 2.1E-27 T 28-03-2018 SmaCSM2_RS07245 43998fa298d963489be233d3327eefd9 135 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 34 118 9.6E-25 T 28-03-2018 IPR031982 Type IV minor pilin ComP SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 490 580 3.4E-17 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 SUPERFAMILY SSF48179 489 590 1.79E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 SUPERFAMILY SSF48179 597 675 3.06E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Gene3D G3DSA:3.90.226.10 8 302 1.6E-64 T 28-03-2018 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Gene3D G3DSA:3.40.50.720 307 490 6.1E-42 T 28-03-2018 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 313 485 8.1E-46 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Gene3D G3DSA:1.10.1040.10 491 585 1.2E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 SUPERFAMILY SSF52096 10 305 4.59E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Gene3D G3DSA:1.10.1040.10 600 684 1.6E-13 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 207 1.8E-38 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS15975 05c774c9e6fb522c9de94db7dada926a 687 SUPERFAMILY SSF51735 311 488 2.04E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17215 4893b2779f7c95e5f305708f9cd9b78e 650 Gene3D G3DSA:3.40.1080.10 2 220 1.7E-13 T 28-03-2018 SmaCSM2_RS17215 4893b2779f7c95e5f305708f9cd9b78e 650 Gene3D G3DSA:3.40.1080.10 231 526 7.2E-65 T 28-03-2018 SmaCSM2_RS17215 4893b2779f7c95e5f305708f9cd9b78e 650 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 367 531 4.8E-37 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain SmaCSM2_RS17215 4893b2779f7c95e5f305708f9cd9b78e 650 SUPERFAMILY SSF100950 302 547 5.98E-40 T 28-03-2018 SmaCSM2_RS17215 4893b2779f7c95e5f305708f9cd9b78e 650 SUPERFAMILY SSF100950 225 269 5.98E-40 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:1.20.1640.10 269 493 3.8E-41 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:1.20.1640.10 849 1060 1.0E-31 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:3.30.2090.10 182 268 1.0E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:3.30.2090.10 747 843 1.0E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82693 41 135 3.14E-17 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82714 184 266 5.62E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:3.30.70.1430 589 697 7.3E-10 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Pfam PF00873 AcrB/AcrD/AcrF family 5 1057 1.3E-198 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 Gene3D G3DSA:3.30.70.1430 41 143 7.2E-19 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82693 269 325 2.98E-13 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82693 137 183 2.98E-13 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-39 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82714 749 839 3.14E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82866 292 492 1.16E-43 T 28-03-2018 SmaCSM2_RS13200 19ca5d58aacea427686af4c1b2eb646a 1072 SUPERFAMILY SSF82866 840 1060 1.44E-43 T 28-03-2018 SmaCSM2_RS11195 903a54bbd5d456a21464b8fe3d6b348c 158 SUPERFAMILY SSF54427 6 158 1.38E-78 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS11195 903a54bbd5d456a21464b8fe3d6b348c 158 Gene3D G3DSA:3.10.450.50 14 158 2.6E-70 T 28-03-2018 SmaCSM2_RS11195 903a54bbd5d456a21464b8fe3d6b348c 158 Pfam PF07080 Protein of unknown function (DUF1348) 11 140 3.0E-64 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 389 4.1E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Gene3D G3DSA:3.90.190.20 320 464 3.6E-48 T 28-03-2018 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Pfam PF08245 Mur ligase middle domain 105 300 5.9E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 SUPERFAMILY SSF53623 101 319 3.92E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 SUPERFAMILY SSF63418 3 92 2.62E-23 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Gene3D G3DSA:3.40.1390.10 1 89 8.2E-25 T 28-03-2018 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 SUPERFAMILY SSF53244 321 453 4.81E-32 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 454 32.417 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Pfam PF01225 Mur ligase family, catalytic domain 25 69 9.7E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 Gene3D G3DSA:3.40.1190.10 90 317 2.1E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS03245 3b28e433a5dbd6b608801aeca8d45b0d 464 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 453 1.4E-133 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 SMART SM00382 99 301 2.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 33.64 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 SUPERFAMILY SSF47446 328 431 9.32E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 SMART SM00962 100 296 4.3E-113 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Pfam PF02978 Signal peptide binding domain 328 428 1.5E-31 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 SMART SM00963 1 86 1.1E-34 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Pfam PF00448 SRP54-type protein, GTPase domain 101 295 3.5E-72 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 7.0E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 SUPERFAMILY SSF52540 42 353 3.61E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Gene3D G3DSA:3.40.50.300 92 297 1.3E-37 T 28-03-2018 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Gene3D G3DSA:1.20.120.140 1 91 3.2E-28 T 28-03-2018 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 Gene3D G3DSA:1.10.260.30 328 433 4.3E-36 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SmaCSM2_RS06050 8a425ae9bf952c19f55c3fa1537aed41 458 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 3.0E-175 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Gene3D G3DSA:3.40.1360.20 252 367 3.9E-31 T 28-03-2018 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SMART SM00493 256 327 8.1E-20 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Gene3D G3DSA:3.90.980.10 107 237 2.0E-42 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Gene3D G3DSA:3.90.580.10 1 101 1.6E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SUPERFAMILY SSF57783 1 100 2.38E-35 T 28-03-2018 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SUPERFAMILY SSF117023 443 574 3.14E-34 T 28-03-2018 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Gene3D G3DSA:1.20.50.20 368 414 3.7E-20 T 28-03-2018 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Pfam PF01807 CHC2 zinc finger 5 100 6.5E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SMART SM00766 446 571 1.1E-31 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Pfam PF10410 DnaB-helicase binding domain of primase 366 418 3.8E-13 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 TIGRFAM TIGR01391 dnaG: DNA primase 3 415 2.3E-139 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 248 9.3E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Gene3D G3DSA:1.10.860.10 430 576 1.1E-31 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Hamap MF_00974 DNA primase [dnaG]. 3 572 28.819 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Pfam PF08278 DNA primase DnaG DnaB-binding 447 570 1.7E-27 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SUPERFAMILY SSF56731 114 418 1.44E-106 T 28-03-2018 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 SMART SM00400 35 89 1.8E-31 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SmaCSM2_RS01845 3bdac14f69c6597afa838b89295976cd 579 Pfam PF13662 Toprim domain 257 320 5.5E-13 T 28-03-2018 IPR006171 TOPRIM domain SmaCSM2_RS13080 ca64b01de40356f8a8b67b8ab3f8631f 476 Pfam PF02530 Porin subfamily 121 420 5.7E-15 T 28-03-2018 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 SmaCSM2_RS13080 ca64b01de40356f8a8b67b8ab3f8631f 476 SUPERFAMILY SSF56935 133 474 2.93E-9 T 28-03-2018 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Gene3D G3DSA:1.10.40.30 424 467 2.1E-20 T 28-03-2018 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Pfam PF10415 Fumarase C C-terminus 414 466 1.2E-19 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00145 Argininosuccinate lyase family signature 139 161 3.0E-5 T 28-03-2018 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 3.0E-5 T 28-03-2018 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 3.0E-5 T 28-03-2018 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Hamap MF_00743 Fumarate hydratase class II [fumC]. 13 468 78.548 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 SUPERFAMILY SSF48557 13 466 2.21E-142 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 5.4E-31 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 5.4E-31 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 5.4E-31 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 5.4E-31 T 28-03-2018 IPR000362 Fumarate lyase family SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Gene3D G3DSA:1.10.275.10 12 144 4.5E-56 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Pfam PF00206 Lyase 21 348 1.2E-98 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SmaCSM2_RS14100 55a3f8fc954439d1b7ed548056dae230 479 Gene3D G3DSA:1.20.200.10 145 423 1.4E-77 T 28-03-2018 SmaCSM2_RS16045 556f29440561d037e0090b051a741778 654 Gene3D G3DSA:1.10.1370.10 47 641 1.3E-65 T 28-03-2018 SmaCSM2_RS16045 556f29440561d037e0090b051a741778 654 SUPERFAMILY SSF55486 342 646 2.28E-190 T 28-03-2018 SmaCSM2_RS16045 556f29440561d037e0090b051a741778 654 SUPERFAMILY SSF55486 41 312 2.28E-190 T 28-03-2018 SmaCSM2_RS16045 556f29440561d037e0090b051a741778 654 Pfam PF01401 Angiotensin-converting enzyme 41 645 2.4E-193 T 28-03-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 SmaCSM2_RS01895 d5530e5b87b1de4e371c2ec674c7f5cc 389 Gene3D G3DSA:2.120.10.30 31 295 1.2E-52 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS01895 d5530e5b87b1de4e371c2ec674c7f5cc 389 Gene3D G3DSA:2.120.10.30 296 381 2.7E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS01895 d5530e5b87b1de4e371c2ec674c7f5cc 389 Pfam PF07995 Glucose / Sorbosone dehydrogenase 55 384 8.5E-131 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SmaCSM2_RS01895 d5530e5b87b1de4e371c2ec674c7f5cc 389 SUPERFAMILY SSF50952 41 382 1.01E-42 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 SMART SM00938 4 105 1.7E-64 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.1E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 Gene3D G3DSA:3.30.70.120 1 108 7.7E-48 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 PIRSF PIRSF039144 1 112 2.7E-52 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 PRINTS PR00340 P-II protein signature 52 75 7.1E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 PRINTS PR00340 P-II protein signature 2 17 7.1E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 PRINTS PR00340 P-II protein signature 83 103 7.1E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 PRINTS PR00340 P-II protein signature 23 41 7.1E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS19950 e7fcc7ef73f0dd8514f7b04a0714ffc4 112 SUPERFAMILY SSF54913 1 112 3.11E-45 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SMART SM00052 178 424 1.5E-95 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SUPERFAMILY SSF141868 185 432 5.23E-81 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Gene3D G3DSA:3.20.20.450 181 434 6.6E-87 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SUPERFAMILY SSF55073 25 167 1.1E-28 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SUPERFAMILY SSF52172 445 570 1.57E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Pfam PF00563 EAL domain 184 419 1.6E-70 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Pfam PF00072 Response regulator receiver domain 449 558 1.6E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 28 167 2.2E-19 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Gene3D G3DSA:3.40.50.2300 438 582 5.2E-27 T 28-03-2018 SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SMART SM00267 18 168 5.3E-11 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Pfam PF00990 Diguanylate cyclase, GGDEF domain 25 163 9.2E-23 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 Gene3D G3DSA:3.30.70.270 20 180 2.5E-30 T 28-03-2018 SmaCSM2_RS10330 a92a94ca964c04528ca786f0e402a1c4 590 SMART SM00448 446 558 3.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02910 50c8b1d7232a96f9f1ac941d464ee36c 368 Pfam PF03739 Predicted permease YjgP/YjgQ family 11 365 1.8E-63 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 SmaCSM2_RS02910 50c8b1d7232a96f9f1ac941d464ee36c 368 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 8 365 2.0E-100 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 SmaCSM2_RS06670 87f7efc1ed13457c5e1aed1d75204770 788 Pfam PF13953 PapC C-terminal domain 706 761 1.4E-6 T 28-03-2018 IPR025949 PapC-like, C-terminal domain SmaCSM2_RS06670 87f7efc1ed13457c5e1aed1d75204770 788 Pfam PF00577 Outer membrane usher protein 203 695 6.6E-24 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 Pfam PF00593 TonB dependent receptor 417 886 2.1E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 SUPERFAMILY SSF56935 25 237 1.85E-95 T 28-03-2018 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 SUPERFAMILY SSF56935 532 887 1.85E-95 T 28-03-2018 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 SUPERFAMILY SSF56935 276 489 1.85E-95 T 28-03-2018 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 32 886 1.6E-182 T 28-03-2018 IPR010104 Bacterial TonB-dependent receptor SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 169 1.1E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 Gene3D G3DSA:2.170.130.10 23 177 5.6E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18240 209b115f4e0d12dd31d52b533c415c14 887 Gene3D G3DSA:2.40.170.20 180 886 1.6E-70 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 3 735 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 SUPERFAMILY SSF53659 2 738 0.0 T 28-03-2018 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 Gene3D G3DSA:3.40.718.10 432 710 5.7E-43 T 28-03-2018 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 739 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 PIRSF PIRSF009407 1 739 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SmaCSM2_RS19505 d50e4996a17bd245ba2ca8cb175f91de 740 Gene3D G3DSA:3.40.718.10 51 368 4.2E-46 T 28-03-2018 SmaCSM2_RS11035 d47d48e8e5f0cd8bd5d083e1ff3174f8 342 Gene3D G3DSA:1.20.120.570 99 224 0.14 T 28-03-2018 SmaCSM2_RS11035 d47d48e8e5f0cd8bd5d083e1ff3174f8 342 Gene3D G3DSA:1.20.120.570 249 318 0.035 T 28-03-2018 SmaCSM2_RS11035 d47d48e8e5f0cd8bd5d083e1ff3174f8 342 Pfam PF11740 Plasmid replication region DNA-binding N-term 25 142 7.2E-24 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 SUPERFAMILY SSF51621 8 424 5.83E-156 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 Pfam PF00463 Isocitrate lyase family 248 424 3.3E-45 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 Pfam PF00463 Isocitrate lyase family 9 247 1.5E-57 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 PIRSF PIRSF001362 1 427 1.5E-238 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 8 247 5.0E-107 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 ProSitePatterns PS00161 Isocitrate lyase signature. 185 190 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 SmaCSM2_RS01005 a5d660b05399af98565c29dfecef4813 433 Gene3D G3DSA:3.20.20.60 4 407 3.4E-149 T 28-03-2018 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 Gene3D G3DSA:3.40.50.10300 208 429 4.1E-64 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 SUPERFAMILY SSF102645 214 427 3.53E-73 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 215 397 5.5E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 Pfam PF02441 Flavoprotein 28 198 3.5E-41 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 24 423 4.0E-132 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 SUPERFAMILY SSF52507 24 198 8.76E-57 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SmaCSM2_RS01610 8a206d5887a924373d86f571a4417639 429 Gene3D G3DSA:3.40.50.1950 20 207 6.7E-52 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SmaCSM2_RS02835 f8c35023611ebac50f863f12a2ba1497 275 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS02835 f8c35023611ebac50f863f12a2ba1497 275 SMART SM00382 46 244 2.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS02835 f8c35023611ebac50f863f12a2ba1497 275 Gene3D G3DSA:3.40.50.300 18 272 1.7E-57 T 28-03-2018 SmaCSM2_RS02835 f8c35023611ebac50f863f12a2ba1497 275 SUPERFAMILY SSF52540 21 247 7.3E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02835 f8c35023611ebac50f863f12a2ba1497 275 Pfam PF00005 ABC transporter 39 188 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 5 319 1.1E-106 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 316 30.387 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 SUPERFAMILY SSF56042 142 308 5.98E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 Pfam PF00586 AIR synthase related protein, N-terminal domain 28 137 1.3E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 Gene3D G3DSA:3.30.1330.10 1 143 1.1E-35 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 PIRSF PIRSF005303 1 319 7.1E-89 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 Gene3D G3DSA:3.90.650.10 144 319 1.9E-42 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 306 7.9E-8 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS03160 59396774cfdeb035cbdc51cbc2e574f6 320 SUPERFAMILY SSF55326 4 137 1.64E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 Pfam PF00704 Glycosyl hydrolases family 18 33 375 4.8E-71 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 ProSitePatterns PS01095 Chitinases family 18 active site. 134 142 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 SUPERFAMILY SSF51445 20 282 3.33E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 SUPERFAMILY SSF51445 347 381 3.33E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 Gene3D G3DSA:3.20.20.80 10 391 2.5E-89 T 28-03-2018 SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 SMART SM00636 29 375 1.2E-95 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SmaCSM2_RS15060 2cd81eaa588728ca595029e40ea8b57a 396 SUPERFAMILY SSF54556 282 346 2.96E-14 T 28-03-2018 IPR029070 Chitinase insertion domain SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 Gene3D G3DSA:3.90.1150.10 314 427 3.4E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 Gene3D G3DSA:1.10.10.10 2 72 8.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 SUPERFAMILY SSF53383 85 426 2.59E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 SMART SM00345 11 70 8.9E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 SUPERFAMILY SSF46785 8 77 1.47E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 Pfam PF00155 Aminotransferase class I and II 143 421 2.5E-24 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 2.6E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 Gene3D G3DSA:3.40.640.10 113 313 2.8E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13010 77cc0210aa9041c101110674f6db89cd 428 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 81 1.3E-4 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Gene3D G3DSA:3.30.470.20 198 391 4.1E-42 T 28-03-2018 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Gene3D G3DSA:3.30.1490.20 130 197 5.5E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 392 52.239 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 SUPERFAMILY SSF56059 114 314 3.36E-58 T 28-03-2018 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 SUPERFAMILY SSF51246 320 391 1.18E-14 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 SUPERFAMILY SSF52440 4 113 9.93E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 391 6.6E-181 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Pfam PF02222 ATP-grasp domain 124 295 3.6E-56 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SmaCSM2_RS05830 7ae0df4ebd49eccc39b88c71eba64fd3 395 Gene3D G3DSA:3.40.50.20 2 123 4.7E-21 T 28-03-2018 SmaCSM2_RS21305 86b96a7f57e667a5d1c63e90e2e42020 401 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 95 389 7.7E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS21305 86b96a7f57e667a5d1c63e90e2e42020 401 SUPERFAMILY SSF111369 97 242 9.42E-16 T 28-03-2018 SmaCSM2_RS21305 86b96a7f57e667a5d1c63e90e2e42020 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 95 285 1.7E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS21305 86b96a7f57e667a5d1c63e90e2e42020 401 Gene3D G3DSA:1.20.1600.10 43 321 5.3E-16 T 28-03-2018 SmaCSM2_RS09320 272b3a26f32bd86ad94f3d0f2bc797a1 242 Gene3D G3DSA:3.40.630.30 107 239 1.1E-13 T 28-03-2018 SmaCSM2_RS09320 272b3a26f32bd86ad94f3d0f2bc797a1 242 SUPERFAMILY SSF55729 86 235 1.19E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS09320 272b3a26f32bd86ad94f3d0f2bc797a1 242 Pfam PF08445 FR47-like protein 161 226 8.1E-5 T 28-03-2018 IPR013653 FR47-like GO:0016747 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 SMART SM00987 59 219 1.0E-39 T 28-03-2018 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 67 76 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 SUPERFAMILY SSF52141 11 231 5.89E-91 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 Pfam PF03167 Uracil DNA glycosylase superfamily 63 218 1.7E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 14 230 39.645 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 15 223 2.3E-81 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 Gene3D G3DSA:3.40.470.10 1 232 3.0E-102 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19425 0f9e27ae6720e30dba9fec68b92292d0 237 SMART SM00986 59 219 1.0E-39 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 Gene3D G3DSA:2.40.128.20 1 163 8.2E-35 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 SUPERFAMILY SSF50814 5 162 4.68E-39 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 Pfam PF08212 Lipocalin-like domain 13 158 1.9E-48 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 PRINTS PR01171 Bacterial lipocalin signature 50 59 1.1E-8 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 PRINTS PR01171 Bacterial lipocalin signature 13 27 1.1E-8 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 PRINTS PR01171 Bacterial lipocalin signature 120 131 1.1E-8 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 PRINTS PR01171 Bacterial lipocalin signature 147 157 1.1E-8 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 ProSitePatterns PS00213 Lipocalin signature. 12 25 - T 28-03-2018 IPR022272 Lipocalin family conserved site SmaCSM2_RS19890 22d235458b055f8cb380695d57d24fd2 164 PIRSF PIRSF036893 1 164 7.1E-49 T 28-03-2018 IPR022271 Lipocalin, ApoD type SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 SUPERFAMILY SSF103473 489 514 4.45E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 SUPERFAMILY SSF103473 31 216 4.45E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 SUPERFAMILY SSF103473 268 439 4.45E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 Pfam PF07690 Major Facilitator Superfamily 36 430 1.4E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 Gene3D G3DSA:1.20.1250.20 271 518 1.2E-23 T 28-03-2018 SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 Gene3D G3DSA:1.20.1250.20 31 217 6.3E-38 T 28-03-2018 SmaCSM2_RS06765 e2d3ccf023ce3034a63064ee4637fcfa 528 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 510 8.3E-155 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 SUPERFAMILY SSF52402 1 220 1.65E-62 T 28-03-2018 SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 Gene3D G3DSA:3.40.50.620 1 221 3.4E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 PIRSF PIRSF006293 1 221 1.8E-78 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 218 55.309 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 205 4.0E-58 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 SmaCSM2_RS16655 fe0dcd1b86c57ad5176d7939586ed570 221 Pfam PF06508 Queuosine biosynthesis protein QueC 3 212 4.0E-77 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 Gene3D G3DSA:3.40.710.10 41 299 8.7E-36 T 28-03-2018 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 SUPERFAMILY SSF56601 46 297 1.1E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 218 233 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 78 95 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 46 70 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 156 180 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 182 207 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 235 250 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 PRINTS PR00118 Beta-lactamase class A signature 120 145 3.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 Pfam PF13354 Beta-lactamase enzyme family 67 274 1.6E-43 T 28-03-2018 SmaCSM2_RS16765 ad21378c3d1c75bec2a8882f45ec3681 304 ProSitePatterns PS00146 Beta-lactamase class-A active site. 80 95 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 Gene3D G3DSA:3.40.190.10 186 273 1.8E-23 T 28-03-2018 SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 Gene3D G3DSA:1.10.10.10 5 91 9.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 Gene3D G3DSA:3.40.190.10 99 185 1.5E-12 T 28-03-2018 SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 1.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 SUPERFAMILY SSF46785 10 90 9.43E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 SUPERFAMILY SSF53850 96 304 9.0E-39 T 28-03-2018 SmaCSM2_RS12055 c346459b30f7dfe11d7d72e8be55268a 308 Pfam PF03466 LysR substrate binding domain 95 302 1.7E-37 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS10230 f94d5ea81c45a0653567a8fccf6b8f78 472 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 231 458 2.6E-48 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 SmaCSM2_RS10230 f94d5ea81c45a0653567a8fccf6b8f78 472 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 123 1.2E-19 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 SmaCSM2_RS10230 f94d5ea81c45a0653567a8fccf6b8f78 472 Gene3D G3DSA:1.20.5.50 400 472 2.4E-5 T 28-03-2018 SmaCSM2_RS10230 f94d5ea81c45a0653567a8fccf6b8f78 472 Pfam PF07196 Flagellin hook IN motif 143 192 1.3E-5 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 298 7.5E-13 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 PIRSF PIRSF000188 1 351 1.6E-149 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 SMART SM00839 143 350 3.3E-74 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 SUPERFAMILY SSF53223 3 143 2.08E-49 T 28-03-2018 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 Gene3D G3DSA:3.40.50.720 143 351 9.0E-37 T 28-03-2018 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 12 126 6.6E-28 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 SUPERFAMILY SSF51735 140 344 3.68E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 Gene3D G3DSA:3.40.50.10860 1 142 7.9E-50 T 28-03-2018 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 73 86 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 175 195 3.2E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 131 153 3.2E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 65 79 3.2E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS15830 1f4a663ac019c3d11930d3712650777b 365 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 285 296 3.2E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SmaCSM2_RS17500 d755d3c27c9b03919cff12c9337ca246 159 Pfam PF01878 EVE domain 6 154 7.9E-54 T 28-03-2018 IPR002740 EVE domain SmaCSM2_RS17500 d755d3c27c9b03919cff12c9337ca246 159 SUPERFAMILY SSF88697 5 157 1.82E-59 T 28-03-2018 IPR015947 PUA-like domain SmaCSM2_RS17500 d755d3c27c9b03919cff12c9337ca246 159 Gene3D G3DSA:3.10.590.10 4 159 6.4E-60 T 28-03-2018 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 PIRSF PIRSF000370 22 233 1.3E-69 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 24 230 36.391 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 Pfam PF13394 4Fe-4S single cluster domain 45 127 3.4E-10 T 28-03-2018 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 SUPERFAMILY SSF102114 47 125 9.81E-15 T 28-03-2018 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 24 233 5.0E-110 T 28-03-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 Gene3D G3DSA:3.20.20.70 44 217 1.6E-17 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS16660 0dc9b482fef63998b6de2af48e9caead 233 Pfam PF04055 Radical SAM superfamily 47 124 2.9E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS05450 a8aab77810ace50bdc83f1a2674feedf 1194 Pfam PF12679 ABC-2 family transporter protein 8 261 1.9E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SmaCSM2_RS05450 a8aab77810ace50bdc83f1a2674feedf 1194 Pfam PF01433 Peptidase family M1 domain 847 1048 1.3E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS05450 a8aab77810ace50bdc83f1a2674feedf 1194 SUPERFAMILY SSF55486 845 1076 1.83E-20 T 28-03-2018 SmaCSM2_RS05450 a8aab77810ace50bdc83f1a2674feedf 1194 Gene3D G3DSA:1.10.390.10 920 1080 3.1E-18 T 28-03-2018 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 7.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 7.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 7.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 7.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 Gene3D G3DSA:1.10.10.10 4 163 5.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 81 115 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 SMART SM00347 42 142 5.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 Pfam PF12802 MarR family 48 106 3.1E-11 T 28-03-2018 SmaCSM2_RS19800 6d9254c39962bcebb51d6ae1a3abf1f0 164 SUPERFAMILY SSF46785 16 153 5.37E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 Gene3D G3DSA:3.40.190.10 177 264 6.2E-23 T 28-03-2018 SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 SUPERFAMILY SSF53850 91 296 4.16E-47 T 28-03-2018 SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 Gene3D G3DSA:3.40.190.10 92 176 1.1E-19 T 28-03-2018 SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 Pfam PF03466 LysR substrate binding domain 88 293 6.8E-46 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 SUPERFAMILY SSF46785 7 110 1.85E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS13820 96c870ddecc38906f4fbf1a9df99267a 301 Gene3D G3DSA:1.10.10.10 4 83 4.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10030 8b1b2b0adc9aff50bec0d16463444f5f 257 Pfam PF07238 PilZ domain 130 244 3.7E-9 T 28-03-2018 IPR009875 PilZ domain GO:0035438 SmaCSM2_RS10030 8b1b2b0adc9aff50bec0d16463444f5f 257 Gene3D G3DSA:2.40.10.220 131 248 5.5E-14 T 28-03-2018 SmaCSM2_RS10030 8b1b2b0adc9aff50bec0d16463444f5f 257 Pfam PF07317 Flagellar regulator YcgR 22 127 4.2E-30 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal SmaCSM2_RS10030 8b1b2b0adc9aff50bec0d16463444f5f 257 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 17 253 30.084 T 28-03-2018 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 SmaCSM2_RS10030 8b1b2b0adc9aff50bec0d16463444f5f 257 Gene3D G3DSA:2.30.110.10 23 130 7.9E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 Gene3D G3DSA:3.10.430.100 63 147 2.6E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 SUPERFAMILY SSF55653 61 148 6.93E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.9E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 24.517 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 3.9E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 SUPERFAMILY SSF55658 1 57 1.38E-18 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 2.9E-43 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS13890 7723c7e92a91d9525a8d5b754216ca8f 149 Gene3D G3DSA:3.40.5.10 1 49 3.8E-23 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Gene3D G3DSA:3.40.50.740 418 661 4.7E-16 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 111 123 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 SMART SM00929 96 136 2.5E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Gene3D G3DSA:3.10.20.30 8 175 2.6E-17 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 SUPERFAMILY SSF54862 89 223 4.18E-37 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 44 61 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 89 3.9E-19 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 SUPERFAMILY SSF50692 675 735 3.39E-11 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 17 607 7.1E-205 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Pfam PF01568 Molydopterin dinucleotide binding domain 658 730 2.5E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Gene3D G3DSA:3.40.50.740 287 417 4.8E-18 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Gene3D G3DSA:2.40.40.20 662 744 4.1E-12 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 96 132 6.7E-16 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 158 168 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Pfam PF00384 Molybdopterin oxidoreductase 522 608 1.6E-8 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 Pfam PF00384 Molybdopterin oxidoreductase 287 415 1.4E-16 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 SUPERFAMILY SSF53706 226 632 1.06E-77 T 28-03-2018 SmaCSM2_RS15145 f3074690eca2515fe61689af244f143c 744 SUPERFAMILY SSF54292 15 86 5.03E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Gene3D G3DSA:3.40.50.620 118 332 3.6E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 131 140 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 SMART SM01016 3 92 1.3E-39 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 SUPERFAMILY SSF47323 435 562 2.03E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Gene3D G3DSA:3.30.1360.70 1 112 2.5E-30 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 562 25.071 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 6.8E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 6.8E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 6.8E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 308 329 6.8E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 SMART SM00836 441 562 1.5E-52 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Pfam PF05746 DALR anticodon binding domain 441 562 1.0E-34 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Pfam PF00750 tRNA synthetases class I (R) 113 410 1.5E-21 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Gene3D G3DSA:3.40.50.620 333 416 1.1E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 5 92 2.5E-25 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 SUPERFAMILY SSF52374 115 452 1.1E-86 T 28-03-2018 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 562 4.8E-124 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 SUPERFAMILY SSF55190 2 112 3.66E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SmaCSM2_RS01595 abd6fc33741782980b400a69118de5b3 562 Gene3D G3DSA:1.10.730.10 417 562 1.4E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 SMART SM00850 145 242 1.6E-25 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 Pfam PF00072 Response regulator receiver domain 7 113 1.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 Gene3D G3DSA:2.20.25.10 206 242 3.1E-8 T 28-03-2018 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 Gene3D G3DSA:3.40.50.2300 4 136 1.3E-27 T 28-03-2018 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 Pfam PF04397 LytTr DNA-binding domain 146 241 4.2E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 Gene3D G3DSA:2.40.50.40 137 205 6.0E-12 T 28-03-2018 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 SMART SM00448 5 113 4.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03335 e037c030547b5c03cbf776f212b39bf2 243 SUPERFAMILY SSF52172 3 124 1.57E-29 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 SUPERFAMILY SSF55040 9 151 3.01E-43 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 SMART SM00852 179 322 1.2E-24 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 Pfam PF01967 MoaC family 11 146 3.4E-37 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 Gene3D G3DSA:3.30.70.640 4 154 4.6E-45 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 SUPERFAMILY SSF53218 178 326 8.77E-38 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 178 316 2.0E-28 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 PIRSF PIRSF036594 11 331 7.7E-87 T 28-03-2018 IPR012247 Bifunctional molybdenum cofactor biosynthesis protein MoaC/MogA GO:0006777 SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 Pfam PF00994 Probable molybdopterin binding domain 179 321 2.1E-31 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS12330 a94ca17bff7579fec4e551fdb84a8b54 331 Gene3D G3DSA:3.40.980.10 175 331 6.8E-34 T 28-03-2018 IPR001453 MoaB/Mog domain SmaCSM2_RS18115 35949e0023ac88108532f9bcb66f67dc 216 PIRSF PIRSF001488 4 214 1.9E-32 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL SmaCSM2_RS18115 35949e0023ac88108532f9bcb66f67dc 216 SUPERFAMILY SSF52833 28 193 8.64E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS18115 35949e0023ac88108532f9bcb66f67dc 216 Pfam PF01323 DSBA-like thioredoxin domain 68 200 3.7E-13 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SmaCSM2_RS18115 35949e0023ac88108532f9bcb66f67dc 216 Gene3D G3DSA:3.40.30.10 25 216 6.1E-36 T 28-03-2018 SmaCSM2_RS18115 35949e0023ac88108532f9bcb66f67dc 216 ProSitePatterns PS00194 Thioredoxin family active site. 53 71 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 Gene3D G3DSA:1.10.1740.10 34 133 1.1E-17 T 28-03-2018 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 Pfam PF04542 Sigma-70 region 2 51 117 1.7E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 Pfam PF08281 Sigma-70, region 4 148 199 2.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 SUPERFAMILY SSF88946 40 127 5.1E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 202 1.1E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 Gene3D G3DSA:1.10.10.10 134 203 3.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10580 f83916b68eb90e3cd17b5bfbb0610c80 207 SUPERFAMILY SSF88659 141 202 1.4E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02590 e144c8b47611506a12b42008bbb78e3b 120 PIRSF PIRSF006113 1 118 1.4E-48 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SmaCSM2_RS02590 e144c8b47611506a12b42008bbb78e3b 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 117 1.6E-36 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SmaCSM2_RS02590 e144c8b47611506a12b42008bbb78e3b 120 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 2 94 1.8E-32 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SmaCSM2_RS02590 e144c8b47611506a12b42008bbb78e3b 120 Gene3D G3DSA:3.30.479.10 1 118 1.9E-41 T 28-03-2018 SmaCSM2_RS02590 e144c8b47611506a12b42008bbb78e3b 120 SUPERFAMILY SSF55620 1 117 4.0E-40 T 28-03-2018 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 Gene3D G3DSA:1.10.10.200 20 73 2.3E-24 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 Pfam PF01709 Transcriptional regulator 7 235 4.3E-87 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 SUPERFAMILY SSF75625 7 240 1.31E-85 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 6 236 6.3E-86 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 Gene3D G3DSA:3.30.70.980 80 175 8.6E-31 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 Gene3D G3DSA:3.30.70.980 176 236 1.8E-6 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS16720 419c516fcbc21e00cd39c0256ad8f658 243 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 2 237 32.878 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS15220 9e5ba325314e7c1ad8ff5a81411dae17 160 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 100 154 5.0E-4 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS15220 9e5ba325314e7c1ad8ff5a81411dae17 160 Gene3D G3DSA:3.10.450.160 30 159 2.1E-16 T 28-03-2018 SmaCSM2_RS15220 9e5ba325314e7c1ad8ff5a81411dae17 160 Pfam PF11776 Nickel/cobalt transporter regulator 103 153 2.8E-13 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS21095 bdaac384db4833ca86976c7b5807a57f 209 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 43 196 3.2E-16 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like SmaCSM2_RS21095 bdaac384db4833ca86976c7b5807a57f 209 Gene3D G3DSA:2.50.20.10 28 203 5.8E-20 T 28-03-2018 SmaCSM2_RS21095 bdaac384db4833ca86976c7b5807a57f 209 SUPERFAMILY SSF89392 30 196 1.65E-16 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 Pfam PF00082 Subtilase family 168 457 4.0E-52 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 407 417 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 173 183 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 Gene3D G3DSA:3.40.50.200 110 471 5.6E-93 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 Gene3D G3DSA:2.60.120.380 482 579 2.3E-12 T 28-03-2018 SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 500 565 2.0E-16 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 SUPERFAMILY SSF52743 118 210 1.09E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 SUPERFAMILY SSF52743 236 468 1.09E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 406 422 1.0E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 168 187 1.0E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS03760 a74115b8a97d2057401f31a7964ceb9f 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 1.0E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 Gene3D G3DSA:3.40.640.10 37 275 2.4E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 Pfam PF00464 Serine hydroxymethyltransferase 8 386 2.2E-183 T 28-03-2018 SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 SUPERFAMILY SSF53383 7 416 2.99E-184 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 Gene3D G3DSA:3.90.1150.10 276 416 1.4E-60 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 53.282 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SmaCSM2_RS03095 35f1851f677925bdde731744ab9dfe32 417 PIRSF PIRSF000412 4 417 2.4E-172 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SmaCSM2_RS20895 c981bb15d9a14c969aa1a8dee6c73976 400 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 382 4.6E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS20895 c981bb15d9a14c969aa1a8dee6c73976 400 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 379 3.1E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS20895 c981bb15d9a14c969aa1a8dee6c73976 400 SMART SM00267 211 383 7.2E-51 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS20895 c981bb15d9a14c969aa1a8dee6c73976 400 Gene3D G3DSA:3.30.70.270 215 390 2.6E-51 T 28-03-2018 SmaCSM2_RS20895 c981bb15d9a14c969aa1a8dee6c73976 400 SUPERFAMILY SSF55073 227 382 1.65E-42 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS07615 61a3e9b56642f616641d179ad0798a03 249 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 15 249 7.0E-101 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type SmaCSM2_RS07615 61a3e9b56642f616641d179ad0798a03 249 Pfam PF14348 Domain of unknown function (DUF4400) 51 246 1.7E-74 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type SmaCSM2_RS00695 abe887abedce84ec10f120a4d5d8132d 325 Gene3D G3DSA:3.90.20.10 15 161 4.1E-5 T 28-03-2018 SmaCSM2_RS00695 abe887abedce84ec10f120a4d5d8132d 325 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 20 320 8.2E-16 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Gene3D G3DSA:3.40.50.970 4 199 3.8E-58 T 28-03-2018 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 SUPERFAMILY SSF52518 373 564 1.63E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 176 1.6E-55 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Gene3D G3DSA:3.40.50.970 349 552 2.4E-49 T 28-03-2018 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 SUPERFAMILY SSF52467 194 358 4.09E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 8.6E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 333 4.4E-41 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 Gene3D G3DSA:3.40.50.1220 200 348 4.8E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 SUPERFAMILY SSF52518 6 190 1.64E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SmaCSM2_RS17745 fba4c9382866945ad99c3832c1928d80 578 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 13 563 2.1E-208 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PIRSF PIRSF000904 1 336 3.7E-122 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PIRSF PIRSF500210 1 335 1.2E-123 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 Gene3D G3DSA:3.30.540.10 7 198 2.2E-57 T 28-03-2018 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 SUPERFAMILY SSF56655 3 330 1.53E-110 T 28-03-2018 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 Gene3D G3DSA:3.40.190.80 199 333 9.4E-54 T 28-03-2018 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 193 5.9E-59 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 332 45.192 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 204 231 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 28 55 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 65 91 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 306 331 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 178 201 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS00190 db0346f3d049e36d245cc85ddd690a92 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 147 170 1.7E-66 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 Gene3D G3DSA:1.10.10.10 119 210 5.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 SUPERFAMILY SSF88946 31 130 8.32E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 Gene3D G3DSA:1.10.1740.10 28 118 3.2E-22 T 28-03-2018 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 207 2.9E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 Pfam PF04542 Sigma-70 region 2 50 116 4.5E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 Pfam PF08281 Sigma-70, region 4 152 201 1.4E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS21165 f883363dfa6763d7fc7696055adc0cbe 217 SUPERFAMILY SSF88659 143 208 1.12E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 Gene3D G3DSA:2.170.130.10 67 203 1.2E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 192 1.6E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 Gene3D G3DSA:2.40.170.20 204 1037 6.2E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 Pfam PF00593 TonB dependent receptor 560 1036 7.2E-29 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 788 833 1.02E-63 T 28-03-2018 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 583 731 1.02E-63 T 28-03-2018 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 874 1037 1.02E-63 T 28-03-2018 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 58 252 1.02E-63 T 28-03-2018 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 474 529 1.02E-63 T 28-03-2018 SmaCSM2_RS15435 7790d4c04e3d88f41c4b88578686b4d0 1038 SUPERFAMILY SSF56935 388 428 1.02E-63 T 28-03-2018 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 Gene3D G3DSA:3.90.1260.10 182 397 6.4E-55 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 SUPERFAMILY SSF69864 175 396 6.8E-55 T 28-03-2018 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 SUPERFAMILY SSF52402 3 185 3.53E-35 T 28-03-2018 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 397 38.99 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 Pfam PF00764 Arginosuccinate synthase 7 392 4.9E-82 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SmaCSM2_RS14625 25dc29f84ca637583ceab56cecd8272f 398 Gene3D G3DSA:3.40.50.620 1 181 3.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 SUPERFAMILY SSF158472 349 399 1.26E-8 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Gene3D G3DSA:1.10.287.950 640 834 4.6E-48 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Gene3D G3DSA:1.10.287.950 351 639 9.4E-20 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Gene3D G3DSA:3.30.450.20 208 325 1.2E-12 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Pfam PF02743 Cache domain 46 266 2.3E-13 T 28-03-2018 IPR033479 Double Cache domain 1 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 SMART SM00283 583 830 3.3E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 SMART SM00304 530 582 41.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 SMART SM00304 349 401 3.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Gene3D G3DSA:3.30.450.20 42 207 4.9E-19 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 SUPERFAMILY SSF58104 550 834 2.88E-71 T 28-03-2018 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 643 797 2.9E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 758 787 5.3E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 321 346 5.3E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 681 708 5.3E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 710 739 5.3E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS18840 ae0fefc47fa54e6d362498feea652748 843 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 604 633 5.3E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10995 3b1bae2d2e67fb6584f5ee6d8c4c1f2e 169 SUPERFAMILY SSF54593 5 159 1.61E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS10995 3b1bae2d2e67fb6584f5ee6d8c4c1f2e 169 Gene3D G3DSA:3.10.180.10 2 164 5.9E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS10995 3b1bae2d2e67fb6584f5ee6d8c4c1f2e 169 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 154 1.3E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS10995 3b1bae2d2e67fb6584f5ee6d8c4c1f2e 169 TIGRFAM TIGR03645 glyox_marine: lactoylglutathione lyase family protein 8 168 1.1E-96 T 28-03-2018 IPR019883 Lactoylglutathione lyase SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 Pfam PF12833 Helix-turn-helix domain 233 311 7.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 Gene3D G3DSA:1.10.10.60 207 265 3.3E-12 T 28-03-2018 SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 Gene3D G3DSA:1.10.10.60 266 314 1.0E-11 T 28-03-2018 SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 SUPERFAMILY SSF46689 210 261 2.69E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 SMART SM00342 227 310 8.5E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12930 fa0f729a42e7de1eaabc8584978eabd9 317 SUPERFAMILY SSF46689 264 312 2.26E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 Gene3D G3DSA:3.30.420.80 5 129 6.6E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 129 32.51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 SUPERFAMILY SSF53137 16 129 6.54E-46 T 28-03-2018 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.8E-54 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 PIRSF PIRSF002131 1 129 4.3E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04100 976f1710a7a6d1c5d4ebd742298383de 129 Pfam PF00411 Ribosomal protein S11 19 128 5.1E-50 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19490 bb252a47a7ef82d2d6dae64e053b8c49 138 SMART SM00960 19 107 7.5E-9 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SmaCSM2_RS19490 bb252a47a7ef82d2d6dae64e053b8c49 138 SUPERFAMILY SSF103196 13 135 4.71E-20 T 28-03-2018 SmaCSM2_RS19490 bb252a47a7ef82d2d6dae64e053b8c49 138 Gene3D G3DSA:3.30.450.30 14 134 2.2E-19 T 28-03-2018 SmaCSM2_RS19490 bb252a47a7ef82d2d6dae64e053b8c49 138 Pfam PF03259 Roadblock/LC7 domain 21 97 9.1E-13 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SmaCSM2_RS09620 98862988ddad11843e3416493bd8a37b 64 Pfam PF00403 Heavy-metal-associated domain 3 59 7.3E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09620 98862988ddad11843e3416493bd8a37b 64 SUPERFAMILY SSF55008 2 61 4.32E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09620 98862988ddad11843e3416493bd8a37b 64 Gene3D G3DSA:3.30.70.100 1 60 1.5E-15 T 28-03-2018 SmaCSM2_RS16615 f8861098a65d1e66c67b00b6a87b9345 178 SUPERFAMILY SSF53955 13 176 7.16E-23 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS16615 f8861098a65d1e66c67b00b6a87b9345 178 Pfam PF00959 Phage lysozyme 88 149 2.9E-5 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 SmaCSM2_RS16615 f8861098a65d1e66c67b00b6a87b9345 178 Gene3D G3DSA:1.10.530.40 2 178 1.0E-36 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 Pfam PF01336 OB-fold nucleic acid binding domain 68 144 4.6E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 Gene3D G3DSA:3.30.930.10 154 499 5.5E-100 T 28-03-2018 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 SUPERFAMILY SSF55681 160 500 8.36E-121 T 28-03-2018 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 242 255 8.3E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 260 277 8.3E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 384 400 8.3E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 207 8.3E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 213 229 8.3E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 Gene3D G3DSA:2.40.50.140 12 153 2.8E-35 T 28-03-2018 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 18 502 43.921 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 Pfam PF00152 tRNA synthetases class II (D, K and N) 161 499 2.1E-83 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 13 502 1.9E-198 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SmaCSM2_RS09895 b71e1a2b9468a8d1f5d025d418f9b692 503 SUPERFAMILY SSF50249 10 153 1.35E-37 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 4.0E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 Gene3D G3DSA:3.90.1170.10 1 137 1.4E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 6.3E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 6.3E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 6.3E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 6.3E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 SUPERFAMILY SSF54686 1 134 2.49E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 2.8E-57 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.5 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04025 c34668c08f332d6427dd99c32eef7488 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 Gene3D G3DSA:1.10.10.10 117 192 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 SUPERFAMILY SSF88946 10 110 1.04E-29 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 188 2.2E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 Gene3D G3DSA:1.10.1740.10 3 116 6.0E-30 T 28-03-2018 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 6 194 9.6E-104 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 SUPERFAMILY SSF88659 127 188 1.74E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 Pfam PF04542 Sigma-70 region 2 29 96 2.7E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS15970 525e7af39ccd63ec0ab34c3562c7538c 206 Pfam PF08281 Sigma-70, region 4 134 185 2.0E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 Gene3D G3DSA:2.60.98.20 151 289 8.7E-30 T 28-03-2018 IPR011491 Flagellar hook protein FlgE SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 328 406 4.4E-20 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 Pfam PF00460 Flagella basal body rod protein 3 33 6.2E-8 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 389 5.6E-103 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 SUPERFAMILY SSF117143 79 368 3.4E-74 T 28-03-2018 SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site SmaCSM2_RS10285 89200ae5736f28015421fb229b0ae353 407 Pfam PF07559 Flagellar basal body protein FlaE 177 288 6.9E-20 T 28-03-2018 IPR011491 Flagellar hook protein FlgE SmaCSM2_RS10475 334ec3e77337cef9ba0939dd71bc591a 342 Gene3D G3DSA:3.40.50.1820 44 331 1.8E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS10475 334ec3e77337cef9ba0939dd71bc591a 342 SUPERFAMILY SSF53474 47 322 7.55E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS10475 334ec3e77337cef9ba0939dd71bc591a 342 Pfam PF00756 Putative esterase 67 231 8.1E-15 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SmaCSM2_RS07965 95f2c311db215ce38a92d758468c4772 165 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 152 5.5E-48 T 28-03-2018 SmaCSM2_RS07965 95f2c311db215ce38a92d758468c4772 165 SUPERFAMILY SSF50475 8 136 5.99E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS07965 95f2c311db215ce38a92d758468c4772 165 Gene3D G3DSA:2.30.110.10 4 164 1.5E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 SUPERFAMILY SSF51735 1 259 5.4E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 Gene3D G3DSA:3.40.50.720 4 261 8.8E-61 T 28-03-2018 SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 4.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19560 3c8be80a881e4fcc0f0c138efaec5c6f 264 Pfam PF00106 short chain dehydrogenase 9 198 2.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 40 419 3.5E-100 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 SUPERFAMILY SSF53187 340 432 2.17E-80 T 28-03-2018 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 SUPERFAMILY SSF53187 28 236 2.17E-80 T 28-03-2018 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 Gene3D G3DSA:3.40.630.10 13 278 4.4E-48 T 28-03-2018 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 Gene3D G3DSA:3.40.630.10 279 438 1.7E-23 T 28-03-2018 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 Pfam PF01546 Peptidase family M20/M25/M40 97 425 1.8E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 Pfam PF07687 Peptidase dimerisation domain 226 322 7.1E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 PIRSF PIRSF005962 25 435 3.0E-116 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SmaCSM2_RS19535 1634af392ee815d4d032e8cb269201b9 439 SUPERFAMILY SSF55031 222 328 3.27E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 179 207 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 Pfam PF00482 Type II secretion system (T2SS), protein F 288 410 6.6E-30 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 Pfam PF00482 Type II secretion system (T2SS), protein F 84 207 4.0E-31 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 399 418 5.0E-18 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 80 92 5.0E-18 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 179 207 5.0E-18 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS16940 f6baa6d651bb211172289a5cb02a1766 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 397 5.0E-18 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS19165 6e96df63537ee75149e424c54079111f 91 SUPERFAMILY SSF82771 8 78 1.57E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS19165 6e96df63537ee75149e424c54079111f 91 Pfam PF01541 GIY-YIG catalytic domain 8 77 5.9E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS19165 6e96df63537ee75149e424c54079111f 91 Gene3D G3DSA:3.40.1440.10 6 82 4.2E-4 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily SmaCSM2_RS16805 e9bfd2586e98f05b6389a583e4200fbc 266 Pfam PF06629 MltA-interacting protein MipA 35 266 7.8E-34 T 28-03-2018 IPR010583 MltA-interacting MipA SmaCSM2_RS05130 eda23105598c03861e067f5264809125 76 SUPERFAMILY SSF82657 3 74 1.28E-22 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS05130 eda23105598c03861e067f5264809125 76 Pfam PF01722 BolA-like protein 23 74 1.2E-17 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS05130 eda23105598c03861e067f5264809125 76 Gene3D G3DSA:3.30.300.90 1 76 4.2E-24 T 28-03-2018 SmaCSM2_RS05130 eda23105598c03861e067f5264809125 76 PIRSF PIRSF003113 2 76 1.4E-20 T 28-03-2018 IPR002634 BolA protein SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 Pfam PF00561 alpha/beta hydrolase fold 35 298 6.5E-31 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 SUPERFAMILY SSF53474 2 311 1.2E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.1E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.1E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 1.1E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 312 1.1E-152 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PIRSF PIRSF006431 1 313 1.3E-136 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 Gene3D G3DSA:3.40.50.1820 1 313 3.1E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 7.6E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 7.6E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS03670 0356977b3b99178ea2604e972a14ac41 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 7.6E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 58 693 3.0E-82 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 Gene3D G3DSA:2.40.170.20 180 693 5.1E-80 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 676 693 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 168 7.7E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 Pfam PF00593 TonB dependent receptor 258 692 1.6E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 Gene3D G3DSA:2.170.130.10 27 174 1.3E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 SUPERFAMILY SSF56935 26 693 1.74E-116 T 28-03-2018 SmaCSM2_RS12665 ece234b01a48d4de146b835d1783e0cf 693 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 44 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Pfam PF08206 Ribonuclease B OB domain 161 218 7.5E-21 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SMART SM00357 160 219 2.1E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SUPERFAMILY SSF50249 141 221 1.09E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SUPERFAMILY SSF50249 212 311 5.57E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 TIGRFAM TIGR02063 RNase_R: ribonuclease R 93 792 1.1E-263 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Pfam PF00773 RNB domain 334 661 2.8E-105 T 28-03-2018 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SUPERFAMILY SSF50249 299 708 5.31E-140 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 ProSitePatterns PS01175 Ribonuclease II family signature. 629 653 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SMART SM00316 708 791 1.6E-12 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Gene3D G3DSA:2.40.50.140 707 792 4.6E-19 T 28-03-2018 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SMART SM00955 334 662 3.2E-176 T 28-03-2018 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Gene3D G3DSA:1.10.10.10 88 159 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Pfam PF00575 S1 RNA binding domain 709 788 2.4E-11 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 154 791 5.5E-217 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Hamap MF_01895 Ribonuclease R [rnr]. 112 791 58.256 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 SUPERFAMILY SSF50249 711 790 4.7E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS06795 674c51208cb66efccec4d209f1c6b5eb 819 Gene3D G3DSA:2.40.50.140 160 215 0.078 T 28-03-2018 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 SUPERFAMILY SSF160246 6 68 1.23E-7 T 28-03-2018 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 SUPERFAMILY SSF52540 90 474 1.35E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 308 322 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 Gene3D G3DSA:3.30.450.90 77 213 7.2E-46 T 28-03-2018 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 Pfam PF00437 Type II/IV secretion system protein 118 380 6.8E-82 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 SMART SM00382 241 393 1.7E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 6 474 4.7E-206 T 28-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12160 1fe8e606bad72942c0949e6d4111bdf5 477 Gene3D G3DSA:3.40.50.300 214 477 5.6E-64 T 28-03-2018 SmaCSM2_RS19495 e5379cf2f646688732bdae4a5e246289 182 Gene3D G3DSA:3.40.50.300 1 178 2.6E-19 T 28-03-2018 SmaCSM2_RS19495 e5379cf2f646688732bdae4a5e246289 182 Pfam PF08477 Ras of Complex, Roc, domain of DAPkinase 5 128 4.3E-8 T 28-03-2018 SmaCSM2_RS19495 e5379cf2f646688732bdae4a5e246289 182 SUPERFAMILY SSF52540 3 172 3.18E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Gene3D G3DSA:3.40.120.10 319 477 2.7E-37 T 28-03-2018 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 SUPERFAMILY SSF55957 683 779 1.19E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 SUPERFAMILY SSF53738 575 681 4.32E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Gene3D G3DSA:3.40.120.10 577 677 1.3E-25 T 28-03-2018 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 575 683 1.9E-21 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 689 768 1.7E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 SUPERFAMILY SSF53738 325 460 7.85E-39 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 472 569 8.1E-29 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 SUPERFAMILY SSF53738 471 571 6.67E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 486 505 3.9E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 520 533 3.9E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 413 427 3.9E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 549 564 3.9E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Gene3D G3DSA:3.30.310.50 678 779 1.1E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 325 451 1.0E-35 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS01620 c941e11647902c2ae753f0feb168e91e 782 Gene3D G3DSA:3.40.120.10 478 576 2.0E-33 T 28-03-2018 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 36 564 3.3E-141 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 SUPERFAMILY SSF56235 32 565 6.75E-168 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 246 262 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 453 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 56 81 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 461 478 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 276 295 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 148 167 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 397 415 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 373 391 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 130 148 7.2E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS08525 4b583e3ce66855e748e4cee8818126cc 576 Pfam PF01019 Gamma-glutamyltranspeptidase 49 565 2.1E-165 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS05325 f14faa6e2d4f562b330d1f9827aee1f7 151 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 130 1.1E-52 T 28-03-2018 IPR014290 SUF system FeS cluster assembly regulator SmaCSM2_RS05325 f14faa6e2d4f562b330d1f9827aee1f7 151 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 130 1.3E-29 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SmaCSM2_RS05325 f14faa6e2d4f562b330d1f9827aee1f7 151 Gene3D G3DSA:1.10.10.10 2 141 3.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05325 f14faa6e2d4f562b330d1f9827aee1f7 151 Pfam PF02082 Transcriptional regulator 3 82 1.1E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SmaCSM2_RS05325 f14faa6e2d4f562b330d1f9827aee1f7 151 SUPERFAMILY SSF46785 3 133 3.54E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 SUPERFAMILY SSF51735 104 292 5.13E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 291 2.9E-61 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 313 4.9E-21 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 SUPERFAMILY SSF52283 5 140 3.59E-30 T 28-03-2018 SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 Gene3D G3DSA:3.40.50.720 5 117 4.8E-25 T 28-03-2018 SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 180 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SmaCSM2_RS15305 8d368e99b0bade21e9a7ef39055ee478 345 Gene3D G3DSA:3.40.50.720 118 294 8.7E-57 T 28-03-2018 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 12 430 48.239 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 SUPERFAMILY SSF56762 29 430 2.09E-132 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 133 430 3.1E-121 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 19 430 1.2E-182 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 Gene3D G3DSA:1.10.645.10 15 242 2.1E-60 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 Gene3D G3DSA:1.10.645.10 243 423 1.6E-42 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS11250 e66b51285cbb1fdf928b1f86e1056424 430 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 56 67 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 Gene3D G3DSA:2.40.170.20 181 852 1.1E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 SUPERFAMILY SSF56935 261 458 1.85E-100 T 28-03-2018 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 SUPERFAMILY SSF56935 496 851 1.85E-100 T 28-03-2018 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 SUPERFAMILY SSF56935 36 233 1.85E-100 T 28-03-2018 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 Pfam PF00593 TonB dependent receptor 385 851 6.6E-41 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 44 852 4.4E-211 T 28-03-2018 IPR010104 Bacterial TonB-dependent receptor SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 Gene3D G3DSA:2.170.130.10 35 173 1.6E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08555 04294ce0e40936423f0283dc370af387 853 Pfam PF07715 TonB-dependent Receptor Plug Domain 70 168 5.3E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 Gene3D G3DSA:3.40.390.10 335 700 1.5E-114 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 507 519 2.2E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 489 501 2.2E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 598 609 2.2E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 528 544 2.2E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 Pfam PF01431 Peptidase family M13 497 696 2.2E-70 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 Pfam PF05649 Peptidase family M13 69 445 2.8E-93 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 Gene3D G3DSA:3.40.390.10 62 301 4.0E-11 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS15440 b0852ae32862137b5d547fae676bf2b6 700 SUPERFAMILY SSF55486 57 700 1.25E-207 T 28-03-2018 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 SUPERFAMILY SSF52540 4 243 2.73E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 Gene3D G3DSA:2.40.50.140 294 345 3.7E-14 T 28-03-2018 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 Pfam PF08402 TOBE domain 281 352 1.8E-8 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 Pfam PF00005 ABC transporter 21 162 6.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 Gene3D G3DSA:3.40.50.300 1 241 2.7E-69 T 28-03-2018 SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 SUPERFAMILY SSF50331 237 360 1.34E-25 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 SMART SM00382 29 211 7.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08420 45f6e47ada27b28feb8801a8ce5517fa 360 Gene3D G3DSA:2.40.50.100 242 293 1.4E-8 T 28-03-2018 SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 Gene3D G3DSA:3.40.50.1820 17 331 1.2E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 103 9.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 9.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 9.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 SUPERFAMILY SSF53474 45 329 4.52E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16300 392af17071d948f0db9057e4cdafc4f5 331 Pfam PF12697 Alpha/beta hydrolase family 64 323 2.2E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11345 ef0b8e9498dc014fe9483e38154a50a9 352 Pfam PF09084 NMT1/THI5 like 48 268 1.9E-22 T 28-03-2018 IPR015168 SsuA/THI5-like SmaCSM2_RS11345 ef0b8e9498dc014fe9483e38154a50a9 352 SUPERFAMILY SSF53850 38 281 1.09E-32 T 28-03-2018 SmaCSM2_RS11345 ef0b8e9498dc014fe9483e38154a50a9 352 Gene3D G3DSA:3.40.190.10 33 140 2.8E-13 T 28-03-2018 SmaCSM2_RS11345 ef0b8e9498dc014fe9483e38154a50a9 352 Gene3D G3DSA:3.40.190.10 141 344 3.8E-26 T 28-03-2018 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 Gene3D G3DSA:2.60.40.200 54 205 7.3E-41 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 SUPERFAMILY SSF49329 63 204 9.03E-43 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 68 204 6.7E-43 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 179 205 1.6E-5 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 138 147 1.6E-5 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 101 123 1.6E-5 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 193 204 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00675 5874334f7b2fc3b80d2bbcb1d2af8799 208 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 101 111 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS02680 8fcbe537b316af431d86823191ba34af 645 Gene3D G3DSA:3.40.50.2000 440 614 3.0E-22 T 28-03-2018 SmaCSM2_RS02680 8fcbe537b316af431d86823191ba34af 645 Pfam PF00534 Glycosyl transferases group 1 463 607 3.5E-14 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SmaCSM2_RS02680 8fcbe537b316af431d86823191ba34af 645 SUPERFAMILY SSF53756 286 640 4.87E-38 T 28-03-2018 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 230 362 5.7E-20 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 PRINTS PR01002 Flagellar protein FlgJ signature 15 38 8.7E-13 T 28-03-2018 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 PRINTS PR01002 Flagellar protein FlgJ signature 60 82 8.7E-13 T 28-03-2018 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 Pfam PF10135 Rod binding protein 37 83 2.0E-14 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 13 363 4.5E-75 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 SMART SM00047 213 368 8.5E-34 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SmaCSM2_RS10260 4f0b4582e4605e12b730423158ad39ed 399 Gene3D G3DSA:1.10.530.10 215 365 5.5E-32 T 28-03-2018 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 Gene3D G3DSA:3.40.50.300 3 438 9.9E-31 T 28-03-2018 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 Pfam PF07664 Ferrous iron transport protein B C terminus 400 452 3.1E-14 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 Pfam PF02421 Ferrous iron transport protein B 11 169 2.7E-54 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 Pfam PF07670 Nucleoside recognition 457 590 2.0E-24 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 Pfam PF07670 Nucleoside recognition 289 382 2.2E-13 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 5.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 33 51 5.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS09790 2c36dfaa2d73a312abe9c6a528c80741 621 SUPERFAMILY SSF52540 10 179 1.65E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 Gene3D G3DSA:3.40.50.1000 3 32 0.13 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 Gene3D G3DSA:3.40.50.1000 77 230 9.9E-26 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 127 189 1.7E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 SUPERFAMILY SSF56784 5 223 5.76E-51 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 Gene3D G3DSA:1.10.150.240 33 76 9.2E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS11490 e2a9229ed90c784d43549341adbee95c 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 188 1.5E-19 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS06060 7a2643e4152d1bc1458ce90fb0a0b51a 270 SUPERFAMILY SSF56752 19 237 2.35E-28 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SmaCSM2_RS06060 7a2643e4152d1bc1458ce90fb0a0b51a 270 Gene3D G3DSA:3.30.470.10 12 94 4.0E-11 T 28-03-2018 SmaCSM2_RS06060 7a2643e4152d1bc1458ce90fb0a0b51a 270 Gene3D G3DSA:3.20.10.10 103 250 5.5E-21 T 28-03-2018 SmaCSM2_RS06060 7a2643e4152d1bc1458ce90fb0a0b51a 270 Pfam PF01063 Amino-transferase class IV 23 224 7.4E-26 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SmaCSM2_RS02250 30c2b600ec4925eda4c0009332f8a9bc 135 SUPERFAMILY SSF54909 3 116 3.38E-31 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS02250 30c2b600ec4925eda4c0009332f8a9bc 135 Gene3D G3DSA:3.30.70.1060 1 119 7.9E-34 T 28-03-2018 SmaCSM2_RS02250 30c2b600ec4925eda4c0009332f8a9bc 135 Pfam PF03795 YCII-related domain 3 116 2.8E-20 T 28-03-2018 IPR005545 YCII-related SmaCSM2_RS16285 61cb9c14b90ea48f4e463ce1b309a8c2 190 SMART SM00867 28 188 5.6E-34 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16285 61cb9c14b90ea48f4e463ce1b309a8c2 190 Pfam PF04264 YceI-like domain 49 182 3.7E-24 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16285 61cb9c14b90ea48f4e463ce1b309a8c2 190 Gene3D G3DSA:2.40.128.110 27 190 3.3E-31 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16285 61cb9c14b90ea48f4e463ce1b309a8c2 190 SUPERFAMILY SSF101874 29 187 1.57E-34 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 503 661 5.5E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Pfam PF00672 HAMP domain 212 260 1.5E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SUPERFAMILY SSF58104 413 694 3.4E-62 T 28-03-2018 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SMART SM00304 303 354 14.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SMART SM00304 393 445 2.7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SMART SM00304 212 264 1.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 181 1.5E-10 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Gene3D G3DSA:1.10.287.950 503 697 2.1E-41 T 28-03-2018 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Gene3D G3DSA:1.10.287.950 219 502 2.6E-22 T 28-03-2018 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 Gene3D G3DSA:1.20.120.30 23 183 3.0E-12 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SUPERFAMILY SSF158472 212 261 1.09E-6 T 28-03-2018 SmaCSM2_RS16100 0fc84b0967e0ef70b0409e786695ccae 707 SMART SM00283 446 693 1.3E-77 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 10 903 16.936 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 Gene3D G3DSA:1.20.1440.90 286 404 7.6E-15 T 28-03-2018 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 SUPERFAMILY SSF51621 18 903 2.51E-255 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 560 572 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 147 158 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 Pfam PF00311 Phosphoenolpyruvate carboxylase 142 903 3.2E-225 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 199 215 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 257 272 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 600 629 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 734 760 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 146 159 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 558 578 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS03375 14c19566e544559af7d94cfda26e6f6a 903 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 402 422 2.3E-50 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 SMART SM00382 45 233 4.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 Pfam PF08402 TOBE domain 297 376 9.7E-20 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 51 376 3.2E-124 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 SUPERFAMILY SSF52540 21 257 1.24E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 Pfam PF00005 ABC transporter 37 178 5.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 Gene3D G3DSA:2.40.50.140 299 368 4.5E-5 T 28-03-2018 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 SUPERFAMILY SSF50331 253 376 2.79E-18 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS07045 f5bb631c69399e5b547dc224feaee122 378 Gene3D G3DSA:3.40.50.300 17 255 3.3E-73 T 28-03-2018 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 SUPERFAMILY SSF54843 1 108 1.7E-41 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.315 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 8.1E-36 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 Gene3D G3DSA:3.90.470.10 1 111 1.5E-40 T 28-03-2018 SmaCSM2_RS04015 e25795fa13672b899b14f6b8ab84ca2c 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.6E-45 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03475 c95cb8f2ee3b6ea6bc1f4d197a34a09b 214 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 197 1.5E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS03475 c95cb8f2ee3b6ea6bc1f4d197a34a09b 214 Gene3D G3DSA:3.40.50.1110 33 214 1.3E-37 T 28-03-2018 SmaCSM2_RS03475 c95cb8f2ee3b6ea6bc1f4d197a34a09b 214 SUPERFAMILY SSF52266 35 213 2.75E-47 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS01750 5fa7ec8fe1e332950ef8cf737b12e11b 230 Gene3D G3DSA:1.20.1540.10 11 219 3.6E-40 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS01750 5fa7ec8fe1e332950ef8cf737b12e11b 230 SUPERFAMILY SSF144091 13 220 5.36E-37 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS01750 5fa7ec8fe1e332950ef8cf737b12e11b 230 Pfam PF01694 Rhomboid family 63 218 2.6E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS18855 4f57c93a42dc27d0d54a595858d32051 154 Pfam PF12802 MarR family 37 89 1.4E-8 T 28-03-2018 SmaCSM2_RS18855 4f57c93a42dc27d0d54a595858d32051 154 SUPERFAMILY SSF46785 5 136 5.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18855 4f57c93a42dc27d0d54a595858d32051 154 Gene3D G3DSA:1.10.10.10 2 152 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 SUPERFAMILY SSF52833 2 78 4.26E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 2.1E-16 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 Gene3D G3DSA:1.20.1050.10 101 227 8.0E-23 T 28-03-2018 SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 SUPERFAMILY SSF47616 88 217 1.25E-22 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 Pfam PF00043 Glutathione S-transferase, C-terminal domain 155 211 3.5E-6 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS08885 a4fa4064a44ac4641ecb818b0b3c9e9c 229 Gene3D G3DSA:3.40.30.10 1 100 2.9E-24 T 28-03-2018 SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 SUPERFAMILY SSF52172 1 172 2.64E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 Gene3D G3DSA:1.10.10.10 119 225 1.6E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 3.7E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 Pfam PF00072 Response regulator receiver domain 3 112 3.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 SMART SM00862 145 218 5.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 SMART SM00448 1 112 1.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS06260 374cb8b4c253755a3f1f27f8045b387f 227 Gene3D G3DSA:3.40.50.2300 1 118 8.0E-31 T 28-03-2018 SmaCSM2_RS14685 a253fab62d9eac60477ac7c54e5e9b19 238 Gene3D G3DSA:3.40.50.150 2 237 3.1E-57 T 28-03-2018 SmaCSM2_RS14685 a253fab62d9eac60477ac7c54e5e9b19 238 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 12 237 39.449 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 SmaCSM2_RS14685 a253fab62d9eac60477ac7c54e5e9b19 238 SUPERFAMILY SSF53335 16 232 1.41E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS14685 a253fab62d9eac60477ac7c54e5e9b19 238 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 14 231 4.8E-88 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 SmaCSM2_RS14685 a253fab62d9eac60477ac7c54e5e9b19 238 Pfam PF13489 Methyltransferase domain 52 206 4.8E-28 T 28-03-2018 SmaCSM2_RS12735 b6e112cfc840b0bad8cd5076ee1feb43 418 SUPERFAMILY SSF52540 147 390 1.43E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS12735 b6e112cfc840b0bad8cd5076ee1feb43 418 Gene3D G3DSA:3.40.50.300 150 392 3.1E-28 T 28-03-2018 SmaCSM2_RS12735 b6e112cfc840b0bad8cd5076ee1feb43 418 Gene3D G3DSA:3.40.50.2300 46 149 7.9E-5 T 28-03-2018 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 8 160 3.8E-56 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 Gene3D G3DSA:3.40.50.620 2 163 2.0E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 SUPERFAMILY SSF52374 6 161 1.07E-44 T 28-03-2018 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 7 163 34.955 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 Pfam PF01467 Cytidylyltransferase-like 10 138 6.8E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 117 139 4.2E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 54 78 4.2E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 25 46 4.2E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 90 106 4.2E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 7 25 4.2E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SmaCSM2_RS08510 ea8de4bb5c9003d8d44c41a834f67fe0 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 64 2.5E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS05110 65bf1fee980a09b70bae142a8e1125e1 188 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 21 159 4.9E-28 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 SmaCSM2_RS05110 65bf1fee980a09b70bae142a8e1125e1 188 Pfam PF03968 OstA-like protein 44 141 7.8E-16 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal SmaCSM2_RS05110 65bf1fee980a09b70bae142a8e1125e1 188 Gene3D G3DSA:2.60.450.10 21 156 1.0E-16 T 28-03-2018 SmaCSM2_RS05110 65bf1fee980a09b70bae142a8e1125e1 188 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 2 159 19.716 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 SmaCSM2_RS01800 6db1b98a22dfa722fef1c3b82b232197 291 Gene3D G3DSA:1.20.120.80 76 291 1.2E-72 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01800 6db1b98a22dfa722fef1c3b82b232197 291 Pfam PF00510 Cytochrome c oxidase subunit III 11 107 3.7E-15 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01800 6db1b98a22dfa722fef1c3b82b232197 291 Pfam PF00510 Cytochrome c oxidase subunit III 150 290 1.3E-45 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01800 6db1b98a22dfa722fef1c3b82b232197 291 SUPERFAMILY SSF81452 9 291 2.09E-84 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01800 6db1b98a22dfa722fef1c3b82b232197 291 Gene3D G3DSA:1.10.287.70 5 75 5.2E-20 T 28-03-2018 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 73 1.8E-23 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 Pfam PF03840 Preprotein translocase SecG subunit 5 72 5.0E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 6.4E-34 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 6.4E-34 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 6.4E-34 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS15185 af2e2fb452f2ad1b5d00210480bd4e77 145 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 6.4E-34 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 SMART SM00387 335 439 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 Gene3D G3DSA:3.30.565.10 215 439 6.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 SUPERFAMILY SSF55874 299 437 1.44E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 437 4.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 1.0E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS19920 2fd8c40aee363e5028ec62f3538cfc9e 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 1.0E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS20900 0117c9bffaf2a3a7d3fb0909a62dbac7 161 PIRSF PIRSF034110 6 156 1.6E-26 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 SmaCSM2_RS20900 0117c9bffaf2a3a7d3fb0909a62dbac7 161 Pfam PF06718 Protein of unknown function (DUF1203) 40 155 1.2E-31 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 138 6.8E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 SUPERFAMILY SSF53738 160 261 2.67E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 SUPERFAMILY SSF55957 363 452 3.27E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 6.7E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 6.7E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 6.7E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 SUPERFAMILY SSF53738 3 186 4.71E-45 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Gene3D G3DSA:3.30.310.50 379 452 2.0E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 449 1.5E-185 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Gene3D G3DSA:3.40.120.10 160 273 7.3E-29 T 28-03-2018 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Gene3D G3DSA:3.40.120.10 274 378 3.6E-25 T 28-03-2018 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 448 8.0E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 451 44.567 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 101 110 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 371 2.2E-28 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 259 1.1E-17 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 SUPERFAMILY SSF53738 263 370 1.73E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SmaCSM2_RS15225 e2fd29b768facc2007372c8766083149 453 Gene3D G3DSA:3.40.120.10 3 159 1.5E-47 T 28-03-2018 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 491 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 SMART SM00387 423 532 2.3E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Pfam PF00512 His Kinase A (phospho-acceptor) domain 315 379 3.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Pfam PF13188 PAS domain 205 264 2.3E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 529 1.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Gene3D G3DSA:3.30.565.10 365 534 1.9E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 SUPERFAMILY SSF55874 373 529 1.28E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Gene3D G3DSA:1.10.287.130 308 364 1.2E-14 T 28-03-2018 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 SMART SM00388 315 381 2.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 Gene3D G3DSA:3.30.450.20 177 307 7.0E-5 T 28-03-2018 SmaCSM2_RS16910 b9122d03d371d9533cdf2f1457a6d034 537 SUPERFAMILY SSF47384 312 379 2.94E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 Pfam PF00593 TonB dependent receptor 314 804 1.4E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 SUPERFAMILY SSF56935 42 392 4.49E-127 T 28-03-2018 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 SUPERFAMILY SSF56935 429 806 4.49E-127 T 28-03-2018 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 Gene3D G3DSA:2.170.130.10 34 176 1.6E-35 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 Gene3D G3DSA:2.40.170.20 180 806 6.0E-83 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05260 4c3f3d95a66933c6fb04077034b5c0ad 806 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 169 3.3E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 210 225 3.1E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 194 210 3.1E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 SUPERFAMILY SSF51206 27 162 1.57E-24 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 Gene3D G3DSA:1.10.10.10 165 245 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 SMART SM00419 188 237 2.6E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 Pfam PF00027 Cyclic nucleotide-binding domain 53 133 1.3E-10 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 SUPERFAMILY SSF46785 168 246 9.27E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 Pfam PF13545 Crp-like helix-turn-helix domain 169 243 7.4E-19 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 Gene3D G3DSA:2.60.120.10 28 164 8.5E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS09515 890f8ac488bceed0293595fb7b708828 250 SMART SM00100 34 152 8.8E-11 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 SUPERFAMILY SSF47616 75 202 6.54E-22 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 Gene3D G3DSA:1.20.1050.10 100 202 1.5E-21 T 28-03-2018 SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 Pfam PF14497 Glutathione S-transferase, C-terminal domain 112 200 1.2E-6 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 5.8E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 SUPERFAMILY SSF52833 4 85 1.06E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14245 423e582cd97f4440dbf11412e83eb5fa 211 Gene3D G3DSA:3.40.30.10 1 99 5.4E-28 T 28-03-2018 SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 Gene3D G3DSA:1.20.1530.10 16 432 2.7E-119 T 28-03-2018 IPR023171 Na/H antiporter domain SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 18 432 19.009 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 Pfam PF13462 Thioredoxin 453 608 1.9E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 22 424 2.7E-83 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 SUPERFAMILY SSF52833 447 608 1.24E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 Gene3D G3DSA:3.40.30.10 448 613 5.0E-34 T 28-03-2018 SmaCSM2_RS20250 93cf571db6a8d86bdb30656baf2a90b4 621 Pfam PF06965 Na+/H+ antiporter 1 20 425 2.4E-118 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SmaCSM2_RS10945 b4f72fc1f6c8e222ffe86abb29c5a0a2 205 Pfam PF01545 Cation efflux family 19 193 2.6E-22 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS10945 b4f72fc1f6c8e222ffe86abb29c5a0a2 205 Gene3D G3DSA:1.20.1510.10 15 195 1.8E-24 T 28-03-2018 SmaCSM2_RS10945 b4f72fc1f6c8e222ffe86abb29c5a0a2 205 SUPERFAMILY SSF161111 12 195 3.14E-39 T 28-03-2018 SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 14 64 2.2E-20 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 Pfam PF00691 OmpA family 173 258 6.0E-15 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 SUPERFAMILY SSF103088 165 276 9.68E-21 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 PRINTS PR01021 OMPA domain signature 222 238 2.5E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 PRINTS PR01021 OMPA domain signature 174 196 2.5E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS02395 4857d074414a93f5a9607ad3aea8687f 312 Gene3D G3DSA:3.30.1330.60 120 294 8.8E-37 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 Gene3D G3DSA:1.20.1250.20 224 546 0.0074 T 28-03-2018 SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 SUPERFAMILY SSF103473 275 447 4.19E-16 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 SUPERFAMILY SSF103473 507 535 4.19E-16 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 SUPERFAMILY SSF103473 33 225 4.19E-16 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 Gene3D G3DSA:1.20.1250.20 30 219 4.4E-15 T 28-03-2018 SmaCSM2_RS06375 fccc21d32505c69264176095abf62755 557 Pfam PF07690 Major Facilitator Superfamily 43 434 1.3E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS17095 2002ab5d55ca886bcacab3c2c43b449c 198 Pfam PF13302 Acetyltransferase (GNAT) domain 33 169 2.5E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS17095 2002ab5d55ca886bcacab3c2c43b449c 198 Gene3D G3DSA:3.40.630.30 13 198 2.1E-26 T 28-03-2018 SmaCSM2_RS17095 2002ab5d55ca886bcacab3c2c43b449c 198 SUPERFAMILY SSF55729 24 193 5.12E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS12140 8648b85d41f51ebeb79c1969a2ac802d 394 Pfam PF12849 PBP superfamily domain 21 336 6.0E-31 T 28-03-2018 IPR024370 PBP domain SmaCSM2_RS12140 8648b85d41f51ebeb79c1969a2ac802d 394 SUPERFAMILY SSF53850 29 389 3.8E-60 T 28-03-2018 SmaCSM2_RS12140 8648b85d41f51ebeb79c1969a2ac802d 394 Gene3D G3DSA:3.40.190.10 121 313 2.8E-28 T 28-03-2018 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 Gene3D G3DSA:2.10.109.10 34 207 6.5E-39 T 28-03-2018 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 ProSitePatterns PS00761 Signal peptidases I signature 3. 164 177 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 SUPERFAMILY SSF51306 38 199 1.69E-46 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 ProSitePatterns PS00501 Signal peptidases I serine active site. 46 53 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 24 197 3.7E-36 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 4.0E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 159 178 4.0E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 37 53 4.0E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS00980 20c751128fb2d0e861d7244e5677b4b2 208 Pfam PF00717 Peptidase S24-like 44 123 4.4E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Gene3D G3DSA:1.10.274.10 41 152 1.7E-25 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 19 579 9.7E-146 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Gene3D G3DSA:3.50.30.10 153 270 7.3E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 SUPERFAMILY SSF52009 126 247 8.76E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Pfam PF05524 PEP-utilising enzyme, N-terminal 21 143 1.1E-23 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 464 482 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 PIRSF PIRSF000732 15 589 1.3E-191 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 SUPERFAMILY SSF47831 41 158 2.88E-26 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Pfam PF00391 PEP-utilising enzyme, mobile domain 170 241 4.2E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 SUPERFAMILY SSF51621 264 559 1.68E-96 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 267 558 4.3E-96 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 309 328 2.3E-26 T 28-03-2018 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 517 529 2.3E-26 T 28-03-2018 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 481 496 2.3E-26 T 28-03-2018 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 2.3E-26 T 28-03-2018 SmaCSM2_RS05065 ecc3dc892aaf4979fffe0111e000bf5d 589 Gene3D G3DSA:3.20.20.60 271 588 4.7E-94 T 28-03-2018 SmaCSM2_RS12435 3ec17c5eb5442aa3d241ab9ac36813ad 208 Gene3D G3DSA:1.25.40.10 3 208 8.4E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12435 3ec17c5eb5442aa3d241ab9ac36813ad 208 SUPERFAMILY SSF48452 14 86 6.56E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS10125 2793e5d38a8b24733885cca94d2dacd8 89 Pfam PF01313 Bacterial export proteins, family 3 10 77 2.9E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 SmaCSM2_RS10125 2793e5d38a8b24733885cca94d2dacd8 89 PIRSF PIRSF004669 1 89 3.6E-22 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 SmaCSM2_RS10125 2793e5d38a8b24733885cca94d2dacd8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 2.7E-13 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 SmaCSM2_RS10125 2793e5d38a8b24733885cca94d2dacd8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 2.7E-13 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 SmaCSM2_RS10125 2793e5d38a8b24733885cca94d2dacd8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 2.7E-13 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 SmaCSM2_RS14490 9fff00774dd3985e2094b4efe70b8ef6 153 Pfam PF03100 CcmE 5 130 6.7E-38 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 SmaCSM2_RS14490 9fff00774dd3985e2094b4efe70b8ef6 153 Gene3D G3DSA:2.40.50.140 27 124 8.1E-28 T 28-03-2018 SmaCSM2_RS14490 9fff00774dd3985e2094b4efe70b8ef6 153 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 140 28.958 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 SmaCSM2_RS14490 9fff00774dd3985e2094b4efe70b8ef6 153 SUPERFAMILY SSF82093 30 136 2.22E-32 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 SmaCSM2_RS07095 e8078a9a7828cf3b962352647643eabe 328 Pfam PF02562 PhoH-like protein 112 315 2.9E-91 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 SmaCSM2_RS07095 e8078a9a7828cf3b962352647643eabe 328 SUPERFAMILY SSF52540 117 312 6.82E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07095 e8078a9a7828cf3b962352647643eabe 328 Gene3D G3DSA:3.40.50.300 111 315 2.3E-24 T 28-03-2018 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 SUPERFAMILY SSF56935 33 730 8.63E-115 T 28-03-2018 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 Pfam PF00593 TonB dependent receptor 252 729 6.4E-41 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 69 730 6.0E-89 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 162 3.8E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 Gene3D G3DSA:2.40.170.20 173 730 3.3E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 713 730 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS05710 97b2c859f42b5b54441c6efd897e1d78 730 Gene3D G3DSA:2.170.130.10 37 172 1.2E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 Pfam PF03466 LysR substrate binding domain 94 301 1.7E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 SUPERFAMILY SSF46785 4 116 7.07E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 Gene3D G3DSA:1.10.10.10 1 93 8.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 69 6.7E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 SUPERFAMILY SSF53850 95 303 1.07E-43 T 28-03-2018 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 Gene3D G3DSA:3.40.190.10 94 177 1.8E-18 T 28-03-2018 SmaCSM2_RS20015 514f6e13fcd8c7aeb164479f7a42cfbf 308 Gene3D G3DSA:3.40.190.10 178 270 2.5E-26 T 28-03-2018 SmaCSM2_RS20480 714491fd6bc3804e69eebff888530586 223 Gene3D G3DSA:3.10.180.10 125 222 0.033 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS20480 714491fd6bc3804e69eebff888530586 223 Gene3D G3DSA:3.10.180.10 1 122 4.4E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS20480 714491fd6bc3804e69eebff888530586 223 SUPERFAMILY SSF54593 1 113 8.82E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 Gene3D G3DSA:3.90.79.10 5 154 1.0E-24 T 28-03-2018 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 PRINTS PR01402 Mutator MutX protein signature 105 125 3.2E-10 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 PRINTS PR01402 Mutator MutX protein signature 74 100 3.2E-10 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 PRINTS PR01402 Mutator MutX protein signature 125 142 3.2E-10 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 PRINTS PR01402 Mutator MutX protein signature 9 27 3.2E-10 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 PRINTS PR01402 Mutator MutX protein signature 27 42 3.2E-10 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 Pfam PF00293 NUDIX domain 12 134 7.1E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS13280 3b1e2b009cd85d7a0596637f62070ae8 162 SUPERFAMILY SSF55811 3 150 1.19E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS20345 8cee09cd369f22b4f897df45c571432e 540 Gene3D G3DSA:1.10.150.130 36 133 0.0021 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS20345 8cee09cd369f22b4f897df45c571432e 540 Gene3D G3DSA:1.10.443.10 226 402 1.2E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS20345 8cee09cd369f22b4f897df45c571432e 540 SUPERFAMILY SSF56349 313 394 6.18E-7 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 PRINTS PR01217 Proline rich extensin signature 63 84 4.6E-10 T 28-03-2018 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 PRINTS PR01217 Proline rich extensin signature 84 100 4.6E-10 T 28-03-2018 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 PRINTS PR01217 Proline rich extensin signature 109 126 4.6E-10 T 28-03-2018 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 144 221 1.2E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 SUPERFAMILY SSF74653 143 219 1.44E-21 T 28-03-2018 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 145 222 1.2E-25 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS00040 1f6ddcc5e7aa29c5a5b8c07cefc89ef5 222 Gene3D G3DSA:3.30.1150.10 64 222 4.7E-21 T 28-03-2018 SmaCSM2_RS09205 58e434ee9c15a1e25e9c16845e6d676f 174 Gene3D G3DSA:3.40.630.30 2 163 7.6E-20 T 28-03-2018 SmaCSM2_RS09205 58e434ee9c15a1e25e9c16845e6d676f 174 SUPERFAMILY SSF55729 11 160 4.43E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS09205 58e434ee9c15a1e25e9c16845e6d676f 174 Pfam PF00583 Acetyltransferase (GNAT) family 61 154 9.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 SMART SM00342 190 273 1.6E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 Gene3D G3DSA:1.10.10.60 170 227 1.0E-7 T 28-03-2018 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 227 269 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 SUPERFAMILY SSF46689 174 220 8.69E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 SUPERFAMILY SSF46689 226 276 1.3E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 Pfam PF12833 Helix-turn-helix domain 196 274 2.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS17710 a6239a736a785b7e56e400b776cc933b 299 Gene3D G3DSA:1.10.10.60 228 278 2.1E-11 T 28-03-2018 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 PIRSF PIRSF039144 1 112 9.7E-54 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 SUPERFAMILY SSF54913 1 112 5.08E-46 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 Gene3D G3DSA:3.30.70.120 1 109 2.4E-50 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 PRINTS PR00340 P-II protein signature 83 103 6.9E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 PRINTS PR00340 P-II protein signature 2 17 6.9E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 PRINTS PR00340 P-II protein signature 52 75 6.9E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 PRINTS PR00340 P-II protein signature 23 41 6.9E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 SMART SM00938 4 105 1.1E-66 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.3E-43 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SmaCSM2_RS00625 c23c8a124138cb2b6f228a2e6aa400ba 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 Gene3D G3DSA:1.10.1660.10 1 59 6.3E-24 T 28-03-2018 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 Pfam PF13411 MerR HTH family regulatory protein 6 71 2.1E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 Gene3D G3DSA:1.10.1660.10 60 135 1.4E-19 T 28-03-2018 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 SMART SM00422 5 74 3.1E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 SUPERFAMILY SSF46955 5 130 3.63E-37 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 8.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 8.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12380 a7cf82d2a770c9ec112526e9dbbd7e8a 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 8.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 Pfam PF01578 Cytochrome C assembly protein 45 187 1.4E-27 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 48 227 1.3E-63 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 159 185 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 48 65 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 65 85 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 103 123 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 124 144 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14480 65e3420dc1d02ac8b6cbaa5821c1e829 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 207 231 1.0E-40 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS09260 39158708f0637074283a93c5568b9867 331 Gene3D G3DSA:3.20.20.30 3 324 3.0E-60 T 28-03-2018 SmaCSM2_RS09260 39158708f0637074283a93c5568b9867 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 323 1.3E-102 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SmaCSM2_RS09260 39158708f0637074283a93c5568b9867 331 Pfam PF00296 Luciferase-like monooxygenase 18 296 1.1E-28 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS09260 39158708f0637074283a93c5568b9867 331 SUPERFAMILY SSF51679 4 322 1.7E-62 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS20665 b608211c4532e42f9d177ef719ef2e8a 294 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 13 264 1.4E-72 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 SmaCSM2_RS20665 b608211c4532e42f9d177ef719ef2e8a 294 SUPERFAMILY SSF53335 10 260 5.22E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS20665 b608211c4532e42f9d177ef719ef2e8a 294 Pfam PF08241 Methyltransferase domain 51 147 2.1E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS20665 b608211c4532e42f9d177ef719ef2e8a 294 Gene3D G3DSA:3.40.50.150 32 272 1.8E-45 T 28-03-2018 SmaCSM2_RS20665 b608211c4532e42f9d177ef719ef2e8a 294 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 5 265 31.748 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 210 228 1.0E-23 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 87 103 1.0E-23 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 112 131 1.0E-23 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 1.0E-23 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 SUPERFAMILY SSF101801 247 321 9.81E-14 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 PIRSF PIRSF002888 1 323 7.2E-93 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 318 3.0E-104 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 316 1.0E-17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 Pfam PF02154 Flagellar motor switch protein FliM 36 228 3.3E-72 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 Gene3D G3DSA:2.30.330.10 236 326 4.9E-18 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 Gene3D G3DSA:3.40.1550.10 44 233 2.6E-39 T 28-03-2018 IPR028976 CheC-like domain SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 SUPERFAMILY SSF103039 5 13 1.18E-19 T 28-03-2018 IPR028976 CheC-like domain SmaCSM2_RS10145 2537df501fd46fd5e03142c47150b5d4 334 SUPERFAMILY SSF103039 53 229 1.18E-19 T 28-03-2018 IPR028976 CheC-like domain SmaCSM2_RS15500 849cb3cffdc336494fd44c93216bfeed 257 Pfam PF00877 NlpC/P60 family 145 254 5.4E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SmaCSM2_RS15500 849cb3cffdc336494fd44c93216bfeed 257 Gene3D G3DSA:3.90.1720.10 128 257 9.3E-38 T 28-03-2018 SmaCSM2_RS15500 849cb3cffdc336494fd44c93216bfeed 257 SUPERFAMILY SSF54001 128 255 4.41E-40 T 28-03-2018 SmaCSM2_RS03770 21d1b95212204aa18488dcf7fb02ef72 111 Pfam PF09842 Predicted membrane protein (DUF2069) 9 100 9.0E-9 T 28-03-2018 IPR018643 Protein of unknown function DUF2069, membrane SmaCSM2_RS16110 3ca8849977f8fb7312fcf9f473c8a6eb 226 Gene3D G3DSA:2.70.70.10 37 213 4.3E-31 T 28-03-2018 SmaCSM2_RS16110 3ca8849977f8fb7312fcf9f473c8a6eb 226 Pfam PF01551 Peptidase family M23 99 206 1.3E-21 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS16110 3ca8849977f8fb7312fcf9f473c8a6eb 226 SUPERFAMILY SSF51261 44 210 1.36E-31 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 Pfam PF14793 Domain of unknown function (DUF4478) 17 123 2.5E-39 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 Gene3D G3DSA:3.40.50.450 134 460 3.1E-93 T 28-03-2018 SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 Pfam PF11892 Domain of unknown function (DUF3412) 342 460 2.1E-52 T 28-03-2018 IPR021826 Domain of unknown function DUF3412 SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 SUPERFAMILY SSF102405 134 338 5.19E-37 T 28-03-2018 SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 Gene3D G3DSA:3.30.1850.10 16 124 7.1E-41 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 SmaCSM2_RS07215 eb2990a2c0f42927983164cd98615afb 462 Pfam PF03641 Possible lysine decarboxylase 199 338 4.1E-28 T 28-03-2018 IPR031100 LOG family SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 Pfam PF04216 Protein involved in formate dehydrogenase formation 18 322 3.4E-96 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 Gene3D G3DSA:3.90.1670.10 20 326 1.9E-80 T 28-03-2018 IPR024064 FdhE-like SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 SUPERFAMILY SSF144020 23 323 1.31E-72 T 28-03-2018 IPR024064 FdhE-like SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 Hamap MF_00611 Protein FdhE [fdhE]. 3 324 31.006 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 PIRSF PIRSF018296 1 327 1.2E-86 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 SmaCSM2_RS17405 492331d4256180f2a9e4fdae9f8dea7f 327 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 321 2.4E-74 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 SMART SM00866 95 232 2.0E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 Gene3D G3DSA:3.40.1410.10 89 238 2.1E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 SUPERFAMILY SSF46785 4 76 3.98E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 Pfam PF07702 UTRA domain 95 230 9.7E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 2.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 9 239 7.8E-82 T 28-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 SUPERFAMILY SSF64288 60 237 4.08E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 Gene3D G3DSA:1.10.10.10 2 74 9.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13680 c0a41902ecfd9f167eb522fe86af4ce0 242 SMART SM00345 13 72 2.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS01580 7723748bb3bd392c33908bab0c9c5739 155 Pfam PF07308 Protein of unknown function (DUF1456) 88 155 1.2E-24 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 SmaCSM2_RS01580 7723748bb3bd392c33908bab0c9c5739 155 Pfam PF07308 Protein of unknown function (DUF1456) 3 72 4.7E-22 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 SmaCSM2_RS03600 bea60e8623d29cc53e63845eb973e97c 132 Gene3D G3DSA:1.10.238.10 90 132 3.4E-6 T 28-03-2018 SmaCSM2_RS03600 bea60e8623d29cc53e63845eb973e97c 132 Gene3D G3DSA:1.10.238.10 19 89 0.0048 T 28-03-2018 SmaCSM2_RS03600 bea60e8623d29cc53e63845eb973e97c 132 SUPERFAMILY SSF47473 77 130 6.39E-7 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Gene3D G3DSA:3.20.19.10 162 363 1.5E-29 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 PIRSF PIRSF036687 1 861 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 856 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 5.6E-94 T 28-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 SUPERFAMILY SSF52016 162 372 3.4E-64 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 ProSitePatterns PS00450 Aconitase family signature 1. 705 722 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 SUPERFAMILY SSF74778 1 160 1.31E-65 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Gene3D G3DSA:3.40.1060.10 524 685 5.3E-28 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Pfam PF11791 Aconitate B N-terminal domain 4 156 7.4E-64 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Gene3D G3DSA:3.30.499.10 405 523 1.9E-10 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Pfam PF00330 Aconitase family (aconitate hydratase) 474 817 8.3E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 SUPERFAMILY SSF53732 380 856 2.75E-144 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS09965 9e3d0202298f3cc41756379b86880c89 863 Gene3D G3DSA:3.30.499.10 686 863 3.9E-49 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SmaCSM2_RS20495 959dbdf7e1431d3f1c067821f9937d48 208 Gene3D G3DSA:3.90.1720.10 21 207 3.6E-29 T 28-03-2018 SmaCSM2_RS20495 959dbdf7e1431d3f1c067821f9937d48 208 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 25 204 8.3E-35 T 28-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family SmaCSM2_RS20495 959dbdf7e1431d3f1c067821f9937d48 208 SUPERFAMILY SSF54001 25 204 3.73E-33 T 28-03-2018 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 PIRSF PIRSF000194 1 163 1.5E-59 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.1E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.1E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.1E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.1E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 SUPERFAMILY SSF53597 1 163 2.36E-55 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 Gene3D G3DSA:3.40.430.10 1 163 1.8E-51 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SmaCSM2_RS03535 54c11406a6b63074b2f42e20996e85c5 163 Pfam PF00186 Dihydrofolate reductase 2 162 7.7E-58 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SmaCSM2_RS01505 423403465ca01ef3139bd8dde4cd55f8 369 Pfam PF01594 AI-2E family transporter 34 355 5.7E-43 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 Gene3D G3DSA:3.40.50.300 38 191 0.046 T 28-03-2018 SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 Gene3D G3DSA:1.10.8.60 410 483 9.4E-6 T 28-03-2018 SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 SUPERFAMILY SSF52540 232 455 7.71E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 SMART SM00382 265 398 2.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 395 3.9E-28 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS00555 29be312d38e7c1bb0bb67e32c0cb6cce 494 Gene3D G3DSA:3.40.50.300 227 409 4.2E-35 T 28-03-2018 SmaCSM2_RS06475 1759e21007cecdd9e507b5e7d1e2b2bb 276 Gene3D G3DSA:3.20.20.410 1 275 2.2E-64 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS06475 1759e21007cecdd9e507b5e7d1e2b2bb 276 SUPERFAMILY SSF117396 10 267 8.24E-60 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS06475 1759e21007cecdd9e507b5e7d1e2b2bb 276 Pfam PF01904 Protein of unknown function DUF72 28 265 2.1E-50 T 28-03-2018 IPR002763 Protein of unknown function DUF72 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 7.5E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 SUPERFAMILY SSF50129 1 184 7.76E-71 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 1.4E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 Gene3D G3DSA:3.40.50.10730 181 312 5.2E-32 T 28-03-2018 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 SUPERFAMILY SSF50129 318 369 2.1E-11 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 Gene3D G3DSA:3.90.180.10 3 180 7.3E-52 T 28-03-2018 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 SUPERFAMILY SSF51735 161 333 9.31E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 SMART SM00829 12 367 1.9E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS18040 815b52c4ad75bf5ece365a37158dfe97 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 5.8E-220 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 SmaCSM2_RS06820 a63f10921286521ee4ef2b4d4247ef6f 413 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 387 8.1E-52 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS06820 a63f10921286521ee4ef2b4d4247ef6f 413 Gene3D G3DSA:1.20.1600.10 33 325 4.7E-36 T 28-03-2018 SmaCSM2_RS06820 a63f10921286521ee4ef2b4d4247ef6f 413 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 268 4.1E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS06820 a63f10921286521ee4ef2b4d4247ef6f 413 SUPERFAMILY SSF111369 53 247 4.71E-24 T 28-03-2018 SmaCSM2_RS14960 e3af8f92fe589a8f47f251ceaae76a33 213 Pfam PF01810 LysE type translocator 19 208 7.9E-38 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS14960 e3af8f92fe589a8f47f251ceaae76a33 213 PIRSF PIRSF006324 1 211 1.3E-56 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS07865 e33eab4936f1aca4ed4b793a9c501cdc 170 SUPERFAMILY SSF52540 12 147 9.19E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07865 e33eab4936f1aca4ed4b793a9c501cdc 170 Gene3D G3DSA:3.40.50.300 7 166 4.2E-17 T 28-03-2018 SmaCSM2_RS07865 e33eab4936f1aca4ed4b793a9c501cdc 170 Pfam PF13671 AAA domain 13 152 6.6E-28 T 28-03-2018 SmaCSM2_RS13940 49c46244dbd176c483d1c1ac4b624f83 173 SUPERFAMILY SSF51182 1 167 1.9E-56 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS13940 49c46244dbd176c483d1c1ac4b624f83 173 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 2 168 35.823 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 SmaCSM2_RS13940 49c46244dbd176c483d1c1ac4b624f83 173 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 6 163 6.4E-73 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 SmaCSM2_RS13940 49c46244dbd176c483d1c1ac4b624f83 173 Gene3D G3DSA:2.60.120.10 7 168 1.2E-44 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS13940 49c46244dbd176c483d1c1ac4b624f83 173 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 3 149 7.1E-67 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 SmaCSM2_RS04000 dd069ba9192c98c0f7bfcfd59848b1f8 99 SUPERFAMILY SSF54189 6 97 4.68E-29 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04000 dd069ba9192c98c0f7bfcfd59848b1f8 99 Pfam PF00276 Ribosomal protein L23 10 95 4.8E-30 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04000 dd069ba9192c98c0f7bfcfd59848b1f8 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.356 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04000 dd069ba9192c98c0f7bfcfd59848b1f8 99 Gene3D G3DSA:3.30.70.330 6 99 3.5E-29 T 28-03-2018 SmaCSM2_RS04000 dd069ba9192c98c0f7bfcfd59848b1f8 99 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 Gene3D G3DSA:3.40.50.1370 174 316 4.4E-44 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 231 240 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 50 72 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 277 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 88 97 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 145 162 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00101 Aspartate carbamoyltransferase signature 296 310 7.0E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 158 9.7E-38 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 12 316 39.096 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 13 315 5.0E-84 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 167 313 4.5E-23 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 SUPERFAMILY SSF53671 11 316 5.37E-89 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 Gene3D G3DSA:3.40.50.1370 4 173 3.0E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 3.1E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 146 157 3.1E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 3.1E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS05040 0d00642e161f4ead7a23d5d2670e51c8 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 280 303 3.1E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 8.9E-58 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 Gene3D G3DSA:3.40.50.1860 1 117 1.1E-31 T 28-03-2018 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 SUPERFAMILY SSF53681 1 116 9.81E-35 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 2.6E-66 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 Gene3D G3DSA:3.40.50.1860 118 215 2.1E-24 T 28-03-2018 SmaCSM2_RS14965 15afcfd99257d824cd1c26e21d64f268 230 SUPERFAMILY SSF53681 118 228 3.76E-31 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 Gene3D G3DSA:3.40.710.10 2 264 1.7E-41 T 28-03-2018 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 36 47 8.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 92 109 8.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 119 132 8.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 12 237 1.5E-54 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SmaCSM2_RS19290 182305a0912c0324e638410e78858133 264 SUPERFAMILY SSF56601 8 254 8.4E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 Hamap MF_00163 Peptide deformylase [def]. 2 165 29.707 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 Gene3D G3DSA:3.90.45.10 1 170 2.6E-61 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 PRINTS PR01576 Peptide deformylase signature 123 152 1.0E-36 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 PRINTS PR01576 Peptide deformylase signature 92 103 1.0E-36 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 PRINTS PR01576 Peptide deformylase signature 104 122 1.0E-36 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 PRINTS PR01576 Peptide deformylase signature 36 65 1.0E-36 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 Pfam PF01327 Polypeptide deformylase 5 155 8.3E-51 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 SUPERFAMILY SSF56420 2 167 1.31E-61 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 162 2.9E-50 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS19055 dc7555cd1a5fc7d271206bfeb842fd11 170 PIRSF PIRSF004749 1 170 5.5E-58 T 28-03-2018 IPR023635 Peptide deformylase SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 30 276 3.6E-114 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 SMART SM00382 54 256 9.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 Pfam PF00005 ABC transporter 45 201 9.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 Gene3D G3DSA:3.40.50.300 28 273 4.1E-63 T 28-03-2018 SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS06880 1b73276dd25227ce3388c7b6cfe9e756 276 SUPERFAMILY SSF52540 30 263 3.06E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 Gene3D G3DSA:2.40.30.10 3 105 8.4E-16 T 28-03-2018 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 SUPERFAMILY SSF52343 112 245 1.7E-31 T 28-03-2018 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00410 Phenol hydroxylase reductase family signature 34 46 2.2E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 154 2.2E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00410 Phenol hydroxylase reductase family signature 101 110 2.2E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 2.2E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 Gene3D G3DSA:3.40.50.80 107 249 6.0E-22 T 28-03-2018 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 Pfam PF00970 Oxidoreductase FAD-binding domain 11 106 1.1E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 Pfam PF00175 Oxidoreductase NAD-binding domain 119 226 2.3E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 SUPERFAMILY SSF63380 5 112 9.14E-17 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 54 61 3.2E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 221 3.2E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 157 168 3.2E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS20915 d8124d9a9e9b63da0ee321112dd956b5 249 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 118 137 3.2E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 Gene3D G3DSA:2.30.38.10 336 440 9.0E-15 T 28-03-2018 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 Gene3D G3DSA:3.40.50.980 185 335 2.6E-29 T 28-03-2018 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 Pfam PF00501 AMP-binding enzyme 15 446 3.2E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 Gene3D G3DSA:3.40.50.980 5 184 1.1E-32 T 28-03-2018 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 Gene3D G3DSA:3.30.300.30 443 552 2.7E-7 T 28-03-2018 SmaCSM2_RS00885 eea63647a8b6539ccc232ec32afdd741 552 SUPERFAMILY SSF56801 5 514 9.81E-86 T 28-03-2018 SmaCSM2_RS16390 bfb5ac51e10932117bee198ca2321074 116 Pfam PF06993 Protein of unknown function (DUF1304) 10 112 8.1E-40 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 SmaCSM2_RS05795 13c9e60de98fa7f43669c45940f169aa 357 SUPERFAMILY SSF55961 26 177 1.23E-12 T 28-03-2018 SmaCSM2_RS05795 13c9e60de98fa7f43669c45940f169aa 357 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 29 175 2.8E-10 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SmaCSM2_RS05795 13c9e60de98fa7f43669c45940f169aa 357 Gene3D G3DSA:3.30.530.20 25 184 2.2E-13 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS05795 13c9e60de98fa7f43669c45940f169aa 357 Gene3D G3DSA:3.20.80.10 189 357 9.0E-19 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 SUPERFAMILY SSF52467 153 331 3.02E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 SUPERFAMILY SSF52518 3 178 1.64E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 1.9E-51 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 188 321 3.1E-27 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 377 523 6.4E-38 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Gene3D G3DSA:3.40.50.970 340 532 6.4E-39 T 28-03-2018 SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Gene3D G3DSA:3.40.50.1220 179 334 8.8E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 SUPERFAMILY SSF52518 354 535 3.75E-56 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS09890 f9246d60dc1ca914ec5098f932828b91 546 Gene3D G3DSA:3.40.50.970 1 178 1.3E-45 T 28-03-2018 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 87 25.286 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 ProSitePatterns PS00323 Ribosomal protein S19 signature. 51 75 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 PIRSF PIRSF002144 1 89 7.9E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 Gene3D G3DSA:3.30.860.10 1 89 1.1E-38 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 Pfam PF00203 Ribosomal protein S19 3 81 2.2E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 PRINTS PR00975 Ribosomal protein S19 family signature 31 50 2.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 PRINTS PR00975 Ribosomal protein S19 family signature 51 63 2.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 PRINTS PR00975 Ribosomal protein S19 family signature 63 78 2.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 87 2.6E-42 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS04010 346a13d222056d035062f97551298c61 89 SUPERFAMILY SSF54570 3 82 6.8E-34 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 Pfam PF00072 Response regulator receiver domain 7 115 8.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 Gene3D G3DSA:1.10.10.10 126 234 5.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 SMART SM00448 5 114 2.4E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 SUPERFAMILY SSF52172 3 129 8.11E-41 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 Gene3D G3DSA:3.40.50.2300 1 125 3.9E-36 T 28-03-2018 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 SMART SM00862 151 228 8.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 SUPERFAMILY SSF46894 131 230 6.52E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS19200 f713925b6fe7280e946332b4a40feb4c 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 228 6.4E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 SUPERFAMILY SSF48008 97 234 6.28E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 Gene3D G3DSA:1.20.120.530 91 248 7.0E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 Gene3D G3DSA:1.10.10.10 1 71 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 SUPERFAMILY SSF46785 3 73 6.64E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 Pfam PF07729 FCD domain 100 227 6.0E-26 T 28-03-2018 IPR011711 GntR, C-terminal SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 SMART SM00895 100 228 2.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 SMART SM00345 10 69 4.1E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 2.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 2.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS12910 7bc0fd5835b1c2a61c8b3d5fc0fb5d8b 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 3.5E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 Pfam PF00717 Peptidase S24-like 69 157 3.2E-19 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 ProSitePatterns PS00760 Signal peptidases I lysine active site. 135 147 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 ProSitePatterns PS00761 Signal peptidases I signature 3. 210 223 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 SUPERFAMILY SSF51306 61 248 9.16E-59 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 Gene3D G3DSA:2.10.109.10 59 259 3.1E-49 T 28-03-2018 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 49 244 1.1E-44 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 133 145 5.1E-23 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 63 79 5.1E-23 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS15950 a9575c1325eb5aee9c8be2114cc5c25d 264 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 205 224 5.1E-23 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SmaCSM2_RS07155 43421c8e724fbc3df07e2683e6124697 150 Gene3D G3DSA:2.30.30.220 12 109 3.0E-34 T 28-03-2018 IPR007481 Stringent starvation protein B SmaCSM2_RS07155 43421c8e724fbc3df07e2683e6124697 150 SUPERFAMILY SSF101738 6 117 6.54E-44 T 28-03-2018 IPR007481 Stringent starvation protein B SmaCSM2_RS07155 43421c8e724fbc3df07e2683e6124697 150 PIRSF PIRSF005276 5 150 1.0E-53 T 28-03-2018 IPR007481 Stringent starvation protein B SmaCSM2_RS07155 43421c8e724fbc3df07e2683e6124697 150 Pfam PF04386 Stringent starvation protein B 11 150 3.4E-32 T 28-03-2018 IPR007481 Stringent starvation protein B SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 Gene3D G3DSA:2.60.120.260 460 584 8.8E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 362 372 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 Pfam PF00082 Subtilase family 77 435 2.3E-36 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 82 93 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 SUPERFAMILY SSF49785 459 587 9.35E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 PRINTS PR00723 Subtilisin serine protease family (S8) signature 121 134 3.9E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 PRINTS PR00723 Subtilisin serine protease family (S8) signature 361 377 3.9E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 PRINTS PR00723 Subtilisin serine protease family (S8) signature 77 96 3.9E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 125 135 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 SUPERFAMILY SSF52743 36 326 4.97E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 SUPERFAMILY SSF52743 353 448 4.97E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 Gene3D G3DSA:3.40.50.200 26 451 8.9E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SmaCSM2_RS20400 424927aed73657d59d8e985a8fde4081 588 Pfam PF01483 Proprotein convertase P-domain 490 583 4.5E-14 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 8 1036 13.431 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 272 705 1.2E-140 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 SMART SM00481 9 76 5.2E-11 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Pfam PF01336 OB-fold nucleic acid binding domain 946 1017 2.1E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Gene3D G3DSA:2.40.50.140 901 1031 1.4E-8 T 28-03-2018 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 SUPERFAMILY SSF89550 119 187 1.45E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 SUPERFAMILY SSF89550 8 86 1.45E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Gene3D G3DSA:3.20.20.140 7 226 5.8E-36 T 28-03-2018 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Pfam PF02811 PHP domain 10 126 4.3E-13 T 28-03-2018 IPR004013 PHP domain GO:0003824 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 Pfam PF14579 Helix-hairpin-helix motif 778 866 2.0E-22 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS13000 9bb70d3a264ff8b33f27a5226ff4b2bf 1036 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 981 1.3E-157 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS18710 aa7e68363e49f11fe789981471e946cf 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 6.2E-41 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 SmaCSM2_RS18710 aa7e68363e49f11fe789981471e946cf 156 Gene3D G3DSA:1.20.5.620 62 122 2.3E-11 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SmaCSM2_RS18710 aa7e68363e49f11fe789981471e946cf 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.805 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SmaCSM2_RS18710 aa7e68363e49f11fe789981471e946cf 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 2.2E-30 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SmaCSM2_RS18710 aa7e68363e49f11fe789981471e946cf 156 SUPERFAMILY SSF81573 62 121 3.27E-12 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SmaCSM2_RS03570 92f3c29f178a06565716d7253d421ca2 857 SUPERFAMILY SSF56935 583 767 1.18E-6 T 28-03-2018 SmaCSM2_RS03570 92f3c29f178a06565716d7253d421ca2 857 Pfam PF04453 Organic solvent tolerance protein 333 754 9.0E-95 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 SmaCSM2_RS03570 92f3c29f178a06565716d7253d421ca2 857 Gene3D G3DSA:2.60.450.10 87 242 2.6E-14 T 28-03-2018 SmaCSM2_RS03570 92f3c29f178a06565716d7253d421ca2 857 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 32 815 19.869 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 SmaCSM2_RS03570 92f3c29f178a06565716d7253d421ca2 857 Pfam PF03968 OstA-like protein 111 227 4.0E-4 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 Hamap MF_01454 GTPase Obg [obg]. 2 337 47.967 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 SUPERFAMILY SSF52540 151 338 6.01E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 SUPERFAMILY SSF82051 3 158 5.1E-58 T 28-03-2018 IPR006169 GTP1/OBG domain SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 Pfam PF01018 GTP1/OBG 4 158 1.2E-60 T 28-03-2018 IPR006169 GTP1/OBG domain SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 PIRSF PIRSF002401 1 350 1.2E-136 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 Gene3D G3DSA:3.40.50.300 159 348 1.0E-31 T 28-03-2018 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 Pfam PF01926 50S ribosome-binding GTPase 161 288 6.0E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 Gene3D G3DSA:2.70.210.12 3 156 1.2E-57 T 28-03-2018 IPR006169 GTP1/OBG domain SmaCSM2_RS05900 428edd258510cf69b0adc9e3b688019e 350 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 335 1.6E-140 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SmaCSM2_RS05970 1a5c09d8eaad63cfc47a043f288fdb8c 957 Gene3D G3DSA:2.40.128.130 585 957 1.1E-34 T 28-03-2018 SmaCSM2_RS05970 1a5c09d8eaad63cfc47a043f288fdb8c 957 SUPERFAMILY SSF103515 642 957 3.01E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS05970 1a5c09d8eaad63cfc47a043f288fdb8c 957 SMART SM00869 677 947 1.0E-28 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS05970 1a5c09d8eaad63cfc47a043f288fdb8c 957 Pfam PF03797 Autotransporter beta-domain 680 936 7.7E-41 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS05970 1a5c09d8eaad63cfc47a043f288fdb8c 957 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 656 957 1.4E-25 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 SmaCSM2_RS16215 69284bfba26c0ca55705aff57afb26fc 153 Pfam PF07681 DoxX 21 103 1.9E-15 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 SUPERFAMILY SSF53448 328 395 3.19E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 SUPERFAMILY SSF53448 75 300 3.19E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 SUPERFAMILY SSF160246 646 699 4.45E-6 T 28-03-2018 SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 Pfam PF13632 Glycosyl transferase family group 2 169 388 2.0E-49 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 Gene3D G3DSA:3.90.550.10 39 371 1.4E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 531 632 5.2E-8 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 SmaCSM2_RS03065 e82b2eedbd09e59c4a8b614aa2de3696 715 SUPERFAMILY SSF160246 492 630 1.67E-15 T 28-03-2018 SmaCSM2_RS16400 c39679916a92fddb655f7652f9f51ff9 466 Gene3D G3DSA:3.40.710.10 67 417 7.4E-74 T 28-03-2018 SmaCSM2_RS16400 c39679916a92fddb655f7652f9f51ff9 466 Pfam PF00144 Beta-lactamase 83 407 1.3E-67 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS16400 c39679916a92fddb655f7652f9f51ff9 466 SUPERFAMILY SSF56601 79 427 2.48E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS18940 675911de3baaa4684aa4d0a32cf7463c 139 Gene3D G3DSA:4.10.430.10 77 116 1.8E-15 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS18940 675911de3baaa4684aa4d0a32cf7463c 139 SUPERFAMILY SSF81273 75 116 2.71E-11 T 28-03-2018 SmaCSM2_RS18940 675911de3baaa4684aa4d0a32cf7463c 139 Pfam PF00816 H-NS histone family 13 108 3.9E-19 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 SmaCSM2_RS18940 675911de3baaa4684aa4d0a32cf7463c 139 SMART SM00528 69 116 1.5E-8 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS17225 9279db80e88257557133f2fe453df8c7 92 SUPERFAMILY SSF143011 1 92 1.39E-14 T 28-03-2018 IPR035095 Toxin RelE-like domain SmaCSM2_RS17225 9279db80e88257557133f2fe453df8c7 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 6.2E-20 T 28-03-2018 IPR007711 Toxin HigB-1 SmaCSM2_RS17225 9279db80e88257557133f2fe453df8c7 92 Gene3D G3DSA:3.30.2310.20 1 92 1.2E-22 T 28-03-2018 SmaCSM2_RS15570 47e138899e92694689eea6af2085e20a 495 Pfam PF10150 Ribonuclease E/G family 128 399 5.4E-103 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 SmaCSM2_RS15570 47e138899e92694689eea6af2085e20a 495 SUPERFAMILY SSF50249 39 132 1.33E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15570 47e138899e92694689eea6af2085e20a 495 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 432 7.4E-157 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 SmaCSM2_RS15570 47e138899e92694689eea6af2085e20a 495 SMART SM00316 37 126 3.4E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS15570 47e138899e92694689eea6af2085e20a 495 Gene3D G3DSA:2.40.50.140 33 131 8.2E-28 T 28-03-2018 SmaCSM2_RS15690 bc34e648489d2db4c7ee3e1e1d90077a 356 SUPERFAMILY SSF56601 33 354 5.11E-92 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS15690 bc34e648489d2db4c7ee3e1e1d90077a 356 Pfam PF00144 Beta-lactamase 33 341 4.4E-72 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS15690 bc34e648489d2db4c7ee3e1e1d90077a 356 Gene3D G3DSA:3.40.710.10 30 355 4.5E-89 T 28-03-2018 SmaCSM2_RS18330 eb84d365fb14a41787211ff2ce97748e 92 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 4 92 17.75 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 SmaCSM2_RS18330 eb84d365fb14a41787211ff2ce97748e 92 Pfam PF04359 Protein of unknown function (DUF493) 11 92 2.0E-19 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 SmaCSM2_RS18330 eb84d365fb14a41787211ff2ce97748e 92 SUPERFAMILY SSF117991 6 92 5.1E-19 T 28-03-2018 IPR027471 YbeD-like domain SmaCSM2_RS18330 eb84d365fb14a41787211ff2ce97748e 92 Gene3D G3DSA:3.30.70.260 9 92 6.6E-19 T 28-03-2018 SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 SUPERFAMILY SSF56300 156 496 4.27E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 Pfam PF09423 PhoD-like phosphatase 158 497 4.5E-96 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 SUPERFAMILY SSF49363 75 147 9.29E-5 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 Gene3D G3DSA:2.60.40.380 48 149 2.2E-6 T 28-03-2018 SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 Gene3D G3DSA:3.60.21.10 152 520 7.5E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS14155 4a3f016ca3f4592516cb3e5f211cb2ff 529 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 49 145 4.1E-30 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SmaCSM2_RS18255 be368a36ef8d4f3f35444a5dcbef87ec 394 SUPERFAMILY SSF53335 21 379 1.06E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS18255 be368a36ef8d4f3f35444a5dcbef87ec 394 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 79 321 1.3E-45 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 SmaCSM2_RS18255 be368a36ef8d4f3f35444a5dcbef87ec 394 Gene3D G3DSA:3.40.50.150 12 323 6.8E-8 T 28-03-2018 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 252 8.3E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 130 973 9.4E-117 T 28-03-2018 IPR010104 Bacterial TonB-dependent receptor SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 SUPERFAMILY SSF56935 378 582 8.79E-78 T 28-03-2018 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 SUPERFAMILY SSF56935 122 333 8.79E-78 T 28-03-2018 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 SUPERFAMILY SSF56935 616 974 8.79E-78 T 28-03-2018 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 SMART SM00965 55 105 6.6E-6 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 Gene3D G3DSA:2.40.170.20 253 977 5.9E-62 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 Pfam PF00593 TonB dependent receptor 509 972 5.4E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08195 a39cfa6fb7fe09cfff8d1673c001f494 977 Gene3D G3DSA:2.170.130.10 122 252 2.9E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05475 7b709edf019ef56fbfa44d6a66b05e93 264 SUPERFAMILY SSF51658 15 262 6.36E-59 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05475 7b709edf019ef56fbfa44d6a66b05e93 264 Pfam PF01261 Xylose isomerase-like TIM barrel 82 217 1.9E-17 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05475 7b709edf019ef56fbfa44d6a66b05e93 264 Gene3D G3DSA:3.20.20.150 12 263 1.4E-37 T 28-03-2018 SmaCSM2_RS08395 f641fbb569d21a6469537b0e4283a1de 219 Gene3D G3DSA:3.20.20.70 3 215 5.8E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS08395 f641fbb569d21a6469537b0e4283a1de 219 SUPERFAMILY SSF51569 7 213 1.83E-61 T 28-03-2018 SmaCSM2_RS08395 f641fbb569d21a6469537b0e4283a1de 219 Pfam PF01081 KDPG and KHG aldolase 13 203 1.2E-59 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS08395 f641fbb569d21a6469537b0e4283a1de 219 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 42 51 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS08395 f641fbb569d21a6469537b0e4283a1de 219 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 12 212 2.8E-74 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SmaCSM2_RS09310 fa02d848109c8d1d86efb4dc440ece58 648 Pfam PF00563 EAL domain 404 635 1.0E-45 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS09310 fa02d848109c8d1d86efb4dc440ece58 648 Gene3D G3DSA:3.20.20.450 399 648 1.8E-64 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS09310 fa02d848109c8d1d86efb4dc440ece58 648 SMART SM00052 393 641 5.2E-46 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS09310 fa02d848109c8d1d86efb4dc440ece58 648 SUPERFAMILY SSF141868 404 646 8.11E-58 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS16335 91e064a5cdc54eb636dd495cb09d0923 657 Pfam PF05170 AsmA family 235 556 3.0E-46 T 28-03-2018 IPR007844 AsmA SmaCSM2_RS16335 91e064a5cdc54eb636dd495cb09d0923 657 Pfam PF05170 AsmA family 28 152 5.8E-16 T 28-03-2018 IPR007844 AsmA SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 TIGRFAM TIGR00761 argB: acetylglutamate kinase 43 264 6.2E-62 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 Pfam PF00696 Amino acid kinase family 44 259 1.6E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 SUPERFAMILY SSF53633 16 294 5.86E-53 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 SUPERFAMILY SSF55729 304 398 7.09E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 Gene3D G3DSA:3.40.1160.10 2 296 1.7E-64 T 28-03-2018 SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 Gene3D G3DSA:3.40.630.30 297 442 4.3E-41 T 28-03-2018 SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 PIRSF PIRSF036441 22 442 1.3E-257 T 28-03-2018 IPR011242 Acetylglutamate kinase ArgB GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SmaCSM2_RS14615 1e664fa8b7b5ef771b1e30fe80c2add1 442 Pfam PF04768 NAT, N-acetyltransferase, of N-acetylglutamate synthase 276 435 8.8E-51 T 28-03-2018 IPR006855 Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|Reactome: R-HSA-70635 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 207 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 Gene3D G3DSA:3.40.50.720 174 290 1.5E-20 T 28-03-2018 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 SUPERFAMILY SSF51735 149 313 7.98E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 Pfam PF00107 Zinc-binding dehydrogenase 186 309 3.8E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 145 4.8E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 SUPERFAMILY SSF50129 8 173 2.43E-53 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 Gene3D G3DSA:3.90.180.10 291 347 9.9E-6 T 28-03-2018 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 Gene3D G3DSA:3.90.180.10 4 173 1.9E-51 T 28-03-2018 SmaCSM2_RS18080 1451df7341a4d25414789e4187471ae9 352 SMART SM00829 11 343 9.9E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS19210 9b5de8ddc6814481f8bcc8a069ae777b 387 Pfam PF00144 Beta-lactamase 30 354 2.6E-37 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS19210 9b5de8ddc6814481f8bcc8a069ae777b 387 SUPERFAMILY SSF56601 26 360 2.07E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS19210 9b5de8ddc6814481f8bcc8a069ae777b 387 Gene3D G3DSA:3.40.710.10 25 366 7.9E-60 T 28-03-2018 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 PIRSF PIRSF038885 5 419 5.1E-155 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 290 393 9.2E-38 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 SUPERFAMILY SSF81648 294 410 1.57E-30 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 Gene3D G3DSA:1.20.810.10 16 415 8.2E-155 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 SUPERFAMILY SSF81342 24 292 1.4E-94 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SmaCSM2_RS07140 09b0d88c5cba6dffea459c07f0212941 419 Pfam PF00033 Cytochrome b/b6/petB 32 220 4.0E-69 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 Gene3D G3DSA:1.10.357.10 65 205 5.8E-16 T 28-03-2018 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 85 198 3.4E-9 T 28-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 Gene3D G3DSA:1.10.260.40 38 64 1.7E-13 T 28-03-2018 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 SUPERFAMILY SSF46689 2 80 8.72E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 SUPERFAMILY SSF48498 83 187 1.16E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS18445 0766ed9a9dadcd9d2b8c1ce8504f7622 219 Gene3D G3DSA:1.10.10.60 2 37 1.5E-15 T 28-03-2018 SmaCSM2_RS10915 9f5ca790de38f54ba4d116ab90753a0f 365 Pfam PF13245 AAA domain 5 188 2.3E-10 T 28-03-2018 SmaCSM2_RS10915 9f5ca790de38f54ba4d116ab90753a0f 365 SUPERFAMILY SSF52540 6 357 4.14E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10915 9f5ca790de38f54ba4d116ab90753a0f 365 Gene3D G3DSA:3.40.50.300 3 240 5.0E-17 T 28-03-2018 SmaCSM2_RS15560 da5cefd10a77681c98a350ec28f76828 481 Gene3D G3DSA:3.30.2290.10 21 234 1.4E-58 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SmaCSM2_RS15560 da5cefd10a77681c98a350ec28f76828 481 SUPERFAMILY SSF111283 24 479 4.45E-136 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS15560 da5cefd10a77681c98a350ec28f76828 481 Pfam PF01523 Putative modulator of DNA gyrase 40 331 1.1E-73 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS15560 da5cefd10a77681c98a350ec28f76828 481 PIRSF PIRSF004919 20 480 5.9E-143 T 28-03-2018 IPR025502 TldD SmaCSM2_RS07820 4c7ea6698e91736bd8b5a5de1e459bf6 173 Gene3D G3DSA:3.40.630.30 1 167 3.2E-32 T 28-03-2018 SmaCSM2_RS07820 4c7ea6698e91736bd8b5a5de1e459bf6 173 SUPERFAMILY SSF55729 1 165 3.09E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS07820 4c7ea6698e91736bd8b5a5de1e459bf6 173 Pfam PF13673 Acetyltransferase (GNAT) domain 41 157 9.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 SUPERFAMILY SSF54675 2 138 1.91E-45 T 28-03-2018 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 Gene3D G3DSA:3.20.140.10 1 393 8.6E-104 T 28-03-2018 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 391 47.81 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 164 390 2.2E-75 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 PIRSF PIRSF000484 1 383 1.4E-69 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 SUPERFAMILY SSF51690 119 388 3.92E-88 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS03025 286856954e02048d2f7d281b71500fb0 393 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 3 390 2.7E-140 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS20100 ba33c87976cf46c551a37df11acfe2f6 145 Pfam PF04273 Putative phosphatase (DUF442) 4 110 2.5E-37 T 28-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 SmaCSM2_RS20100 ba33c87976cf46c551a37df11acfe2f6 145 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 3 136 2.9E-39 T 28-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 SmaCSM2_RS20100 ba33c87976cf46c551a37df11acfe2f6 145 Gene3D G3DSA:3.90.190.10 1 140 6.6E-10 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS20100 ba33c87976cf46c551a37df11acfe2f6 145 SUPERFAMILY SSF52799 10 108 3.32E-7 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS08875 59b4736ebf7f32a461ce5e50dc68ef4f 162 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 29 157 1.5E-49 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 SmaCSM2_RS08875 59b4736ebf7f32a461ce5e50dc68ef4f 162 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 13 159 32.695 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 SmaCSM2_RS14950 64f3280ebdd0a1ec4a7b49d5d34205ed 110 SUPERFAMILY SSF103481 6 107 3.66E-22 T 28-03-2018 SmaCSM2_RS14950 64f3280ebdd0a1ec4a7b49d5d34205ed 110 Pfam PF00893 Small Multidrug Resistance protein 4 94 4.0E-32 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SmaCSM2_RS20585 92304564495d45d6db925cae9b8e12ca 384 Pfam PF01380 SIS domain 230 354 2.8E-6 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS20585 92304564495d45d6db925cae9b8e12ca 384 Pfam PF01380 SIS domain 57 190 1.5E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS20585 92304564495d45d6db925cae9b8e12ca 384 SUPERFAMILY SSF53697 20 375 3.0E-43 T 28-03-2018 SmaCSM2_RS20585 92304564495d45d6db925cae9b8e12ca 384 Gene3D G3DSA:3.40.50.10490 19 193 5.5E-22 T 28-03-2018 SmaCSM2_RS20585 92304564495d45d6db925cae9b8e12ca 384 Gene3D G3DSA:3.40.50.10490 214 367 6.4E-18 T 28-03-2018 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 17 336 47.975 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 Gene3D G3DSA:3.20.20.70 20 261 2.2E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 SUPERFAMILY SSF51395 22 314 7.73E-70 T 28-03-2018 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 Pfam PF01207 Dihydrouridine synthase (Dus) 25 322 1.4E-78 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS01305 c0fe41bdc007ea1b552987c1c92fefc5 343 PIRSF PIRSF006621 11 328 2.6E-77 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 Gene3D G3DSA:2.40.170.20 244 1066 2.7E-56 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF56935 354 647 3.53E-58 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF56935 693 738 3.53E-58 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF56935 780 896 3.53E-58 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF56935 962 1021 3.53E-58 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF56935 112 315 3.53E-58 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 SUPERFAMILY SSF49464 25 125 6.28E-12 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 Gene3D G3DSA:2.170.130.10 123 243 2.2E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 Pfam PF13620 Carboxypeptidase regulatory-like domain 26 106 6.1E-16 T 28-03-2018 SmaCSM2_RS07210 773045b1d26ab5670a16f6f619d5805a 1066 Gene3D G3DSA:2.60.40.1120 25 122 4.2E-15 T 28-03-2018 SmaCSM2_RS00985 046627f4dff822c49bfc9ad1d3828414 418 SUPERFAMILY SSF103473 20 409 1.12E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS00985 046627f4dff822c49bfc9ad1d3828414 418 Gene3D G3DSA:1.20.1250.20 224 413 3.2E-17 T 28-03-2018 SmaCSM2_RS00985 046627f4dff822c49bfc9ad1d3828414 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 88 104 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS00985 046627f4dff822c49bfc9ad1d3828414 418 Gene3D G3DSA:1.20.1250.20 26 223 4.2E-35 T 28-03-2018 SmaCSM2_RS00985 046627f4dff822c49bfc9ad1d3828414 418 Pfam PF07690 Major Facilitator Superfamily 38 342 1.6E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 5.0E-26 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 Pfam PF01632 Ribosomal protein L35 2 62 6.9E-25 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.0E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.0E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.0E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.708 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS15025 7a6be84c7727cda45fbd21f78cee01b6 65 SUPERFAMILY SSF143034 2 64 2.35E-23 T 28-03-2018 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 SUPERFAMILY SSF56935 33 719 6.92E-115 T 28-03-2018 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 168 1.6E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 Pfam PF00593 TonB dependent receptor 277 717 2.2E-40 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 719 4.1E-110 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 Gene3D G3DSA:2.170.130.10 32 177 3.7E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18145 d08ac513fe311ab10d0c440439ec36a7 719 Gene3D G3DSA:2.40.170.20 180 719 8.1E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08695 ce8cfb3175f8b3263d38c50f08e43362 143 SUPERFAMILY SSF55729 37 140 9.96E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS08695 ce8cfb3175f8b3263d38c50f08e43362 143 Pfam PF00583 Acetyltransferase (GNAT) family 62 118 2.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS08695 ce8cfb3175f8b3263d38c50f08e43362 143 Gene3D G3DSA:3.40.630.30 36 140 6.5E-22 T 28-03-2018 SmaCSM2_RS15610 dea3edf2d36112db95efefa2a0a90925 136 Pfam PF02410 Ribosomal silencing factor during starvation 29 122 7.4E-27 T 28-03-2018 SmaCSM2_RS15610 dea3edf2d36112db95efefa2a0a90925 136 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 26 122 1.0E-35 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SmaCSM2_RS15610 dea3edf2d36112db95efefa2a0a90925 136 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 21 123 24.837 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SmaCSM2_RS15610 dea3edf2d36112db95efefa2a0a90925 136 Gene3D G3DSA:3.30.460.10 20 136 2.1E-35 T 28-03-2018 SmaCSM2_RS15610 dea3edf2d36112db95efefa2a0a90925 136 SUPERFAMILY SSF81301 22 126 2.45E-37 T 28-03-2018 SmaCSM2_RS12575 40a27e18db5fe7f19f90db4c2b71bb8f 182 Gene3D G3DSA:3.40.30.10 48 178 8.7E-17 T 28-03-2018 SmaCSM2_RS12575 40a27e18db5fe7f19f90db4c2b71bb8f 182 SUPERFAMILY SSF52833 9 165 2.09E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS12575 40a27e18db5fe7f19f90db4c2b71bb8f 182 Pfam PF13905 Thioredoxin-like 52 146 6.3E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20455 a57b20e9a2edf0568db31fddcf9ee8dc 433 SUPERFAMILY SSF53383 60 431 2.42E-62 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS20455 a57b20e9a2edf0568db31fddcf9ee8dc 433 Gene3D G3DSA:3.90.1150.10 314 433 6.5E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS20455 a57b20e9a2edf0568db31fddcf9ee8dc 433 Pfam PF00266 Aminotransferase class-V 86 386 6.5E-37 T 28-03-2018 IPR000192 Aminotransferase class V domain SmaCSM2_RS20455 a57b20e9a2edf0568db31fddcf9ee8dc 433 Gene3D G3DSA:3.40.640.10 79 313 1.2E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS21100 c41a108fa75fec9f8bf0788e0ce49fda 143 SUPERFAMILY SSF54637 15 138 2.01E-32 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS21100 c41a108fa75fec9f8bf0788e0ce49fda 143 Gene3D G3DSA:3.10.129.10 4 139 3.4E-27 T 28-03-2018 SmaCSM2_RS21100 c41a108fa75fec9f8bf0788e0ce49fda 143 Pfam PF13279 Thioesterase-like superfamily 20 124 8.9E-12 T 28-03-2018 SmaCSM2_RS13425 85c20dc72972cf4c81cbf6ba1d3eda15 417 Pfam PF03743 Bacterial conjugation TrbI-like protein 227 409 1.6E-46 T 28-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 Gene3D G3DSA:2.30.40.10 29 64 0.0025 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 SUPERFAMILY SSF51338 7 14 1.22E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 SUPERFAMILY SSF51338 339 369 1.22E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 PIRSF PIRSF038994 21 371 6.7E-99 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 SUPERFAMILY SSF51556 50 338 8.32E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 Gene3D G3DSA:3.20.20.140 65 339 3.2E-83 T 28-03-2018 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 37 365 2.0E-68 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SmaCSM2_RS20605 36dcd4f2c7d509341dbf144edd5fe6f9 375 Pfam PF01979 Amidohydrolase family 46 368 2.4E-18 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 Pfam PF01144 Coenzyme A transferase 7 198 3.6E-42 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 Gene3D G3DSA:3.40.1080.10 3 209 5.7E-71 T 28-03-2018 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 207 3.7E-100 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 SUPERFAMILY SSF100950 3 208 1.88E-72 T 28-03-2018 SmaCSM2_RS02810 c2cf324db82a2a2ff97a8d1afb2b705a 210 SMART SM00882 6 202 1.0E-76 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS06250 e70d0c4d496556b9998ccf4bf9ee8006 278 PIRSF PIRSF017388 1 154 8.9E-36 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 SmaCSM2_RS06250 e70d0c4d496556b9998ccf4bf9ee8006 278 PIRSF PIRSF017388 157 268 7.5E-17 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 SmaCSM2_RS06250 e70d0c4d496556b9998ccf4bf9ee8006 278 Gene3D G3DSA:3.40.50.1820 10 267 6.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS06250 e70d0c4d496556b9998ccf4bf9ee8006 278 Pfam PF12146 Serine aminopeptidase, S33 16 251 5.9E-21 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS06250 e70d0c4d496556b9998ccf4bf9ee8006 278 SUPERFAMILY SSF53474 10 260 6.68E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS01675 12cfc3837c9c3890e3c72a8d2aad06ac 434 SUPERFAMILY SSF103473 26 428 3.4E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS01675 12cfc3837c9c3890e3c72a8d2aad06ac 434 Gene3D G3DSA:1.20.1250.20 226 428 1.7E-14 T 28-03-2018 SmaCSM2_RS01675 12cfc3837c9c3890e3c72a8d2aad06ac 434 Gene3D G3DSA:1.20.1250.20 14 225 5.7E-18 T 28-03-2018 SmaCSM2_RS01675 12cfc3837c9c3890e3c72a8d2aad06ac 434 Pfam PF07690 Major Facilitator Superfamily 28 384 1.1E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS10490 707904aed4eb7b0ca750b44980b9b3be 347 Pfam PF01032 FecCD transport family 22 339 1.8E-94 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SmaCSM2_RS10490 707904aed4eb7b0ca750b44980b9b3be 347 SUPERFAMILY SSF81345 6 340 1.7E-85 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SmaCSM2_RS10490 707904aed4eb7b0ca750b44980b9b3be 347 Gene3D G3DSA:1.10.3470.10 6 347 1.5E-80 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SmaCSM2_RS14115 0dc5bc91aed95f2bfdc4f6f7c7d6870d 298 SUPERFAMILY SSF55729 3 141 4.63E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS14115 0dc5bc91aed95f2bfdc4f6f7c7d6870d 298 Pfam PF13673 Acetyltransferase (GNAT) domain 22 138 4.6E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS14115 0dc5bc91aed95f2bfdc4f6f7c7d6870d 298 Gene3D G3DSA:3.40.630.30 2 170 1.5E-32 T 28-03-2018 SmaCSM2_RS10875 11f960f37dbaf35c19f88d0a6a1d3fcc 250 Gene3D G3DSA:1.10.760.10 40 190 1.6E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS10875 11f960f37dbaf35c19f88d0a6a1d3fcc 250 SUPERFAMILY SSF46626 10 170 1.77E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS10875 11f960f37dbaf35c19f88d0a6a1d3fcc 250 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 67 146 3.6E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 SUPERFAMILY SSF47616 85 197 2.51E-27 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 SUPERFAMILY SSF52833 1 78 1.64E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 Gene3D G3DSA:1.20.1050.10 98 200 6.8E-24 T 28-03-2018 SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 Gene3D G3DSA:3.40.30.10 1 97 5.1E-21 T 28-03-2018 SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 4.1E-7 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS14140 c20f80c85603bb50d7d08806d943939b 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 104 189 1.2E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 Pfam PF13087 AAA domain 992 1122 3.7E-9 T 28-03-2018 SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 Gene3D G3DSA:3.40.50.300 936 1151 6.6E-14 T 28-03-2018 SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 Gene3D G3DSA:3.40.50.300 345 875 1.8E-19 T 28-03-2018 SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 SUPERFAMILY SSF52540 817 890 6.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 SUPERFAMILY SSF52540 426 451 6.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 SUPERFAMILY SSF52540 335 386 6.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 SUPERFAMILY SSF52540 929 1123 6.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10530 315b863a101f129c604c835e45200113 1159 Pfam PF13086 AAA domain 808 877 9.3E-7 T 28-03-2018 SmaCSM2_RS13750 84fa05786f67ef6eef102fe7713460f1 181 Pfam PF13279 Thioesterase-like superfamily 33 150 3.4E-21 T 28-03-2018 SmaCSM2_RS13750 84fa05786f67ef6eef102fe7713460f1 181 Gene3D G3DSA:3.10.129.10 25 152 5.8E-27 T 28-03-2018 SmaCSM2_RS13750 84fa05786f67ef6eef102fe7713460f1 181 SUPERFAMILY SSF54637 28 151 4.59E-23 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 SUPERFAMILY SSF53901 7 325 2.45E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 Gene3D G3DSA:3.40.47.10 6 164 2.2E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 5 325 73.317 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 324 9.3E-141 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 Gene3D G3DSA:3.40.47.10 165 325 2.6E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 187 5.4E-35 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS04785 49a77ccf9ac4a770a6d3868ee630cf24 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 325 4.6E-36 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SmaCSM2_RS08865 bd12418be3fbd48a2f78a25e10f473b0 182 SUPERFAMILY SSF52980 2 178 8.85E-68 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS08865 bd12418be3fbd48a2f78a25e10f473b0 182 SMART SM01322 1 176 7.2E-111 T 28-03-2018 IPR009822 YaeQ SmaCSM2_RS08865 bd12418be3fbd48a2f78a25e10f473b0 182 PIRSF PIRSF011484 1 180 8.9E-65 T 28-03-2018 IPR009822 YaeQ SmaCSM2_RS08865 bd12418be3fbd48a2f78a25e10f473b0 182 Gene3D G3DSA:3.10.640.10 2 177 1.4E-74 T 28-03-2018 SmaCSM2_RS08865 bd12418be3fbd48a2f78a25e10f473b0 182 Pfam PF07152 YaeQ protein 1 172 4.6E-73 T 28-03-2018 IPR009822 YaeQ SmaCSM2_RS20745 87f1a8a73e5f03bd1a2cc260ecc26ce6 394 Gene3D G3DSA:3.40.50.880 22 295 7.3E-10 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS20745 87f1a8a73e5f03bd1a2cc260ecc26ce6 394 SUPERFAMILY SSF52317 49 283 7.1E-5 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 SUPERFAMILY SSF55874 263 426 5.11E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 SMART SM00388 208 273 6.8E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 SMART SM00304 155 207 0.0026 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 Gene3D G3DSA:3.30.565.10 278 429 4.7E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 426 1.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 SMART SM00387 318 428 1.8E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 Gene3D G3DSA:1.10.287.130 198 269 4.2E-10 T 28-03-2018 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 SUPERFAMILY SSF47384 192 272 1.55E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16800 6ed0181e33741792831a6a141c12d7f6 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 272 5.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 452 2.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 SMART SM00388 244 310 5.4E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 8.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 310 5.5E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 SMART SM00387 350 455 7.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 Gene3D G3DSA:1.10.287.130 234 306 6.5E-14 T 28-03-2018 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 Gene3D G3DSA:3.30.565.10 308 453 2.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 SMART SM00304 189 243 0.0067 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 SUPERFAMILY SSF47384 227 311 3.92E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16960 24a011e004160589008c0c9276c4adc9 456 SUPERFAMILY SSF55874 314 452 3.54E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10455 11e727a77770cf6826f11532a1e8c38d 212 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 212 29.894 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 SmaCSM2_RS10455 11e727a77770cf6826f11532a1e8c38d 212 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 38 202 3.9E-49 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like SmaCSM2_RS10455 11e727a77770cf6826f11532a1e8c38d 212 SUPERFAMILY SSF89392 28 211 7.85E-44 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SmaCSM2_RS10455 11e727a77770cf6826f11532a1e8c38d 212 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 18 209 2.9E-21 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 SmaCSM2_RS10455 11e727a77770cf6826f11532a1e8c38d 212 Gene3D G3DSA:2.50.20.10 26 212 3.1E-40 T 28-03-2018 SmaCSM2_RS06990 b54bd60b355dd20965aa24587e4abda0 433 Pfam PF07690 Major Facilitator Superfamily 273 421 7.1E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS06990 b54bd60b355dd20965aa24587e4abda0 433 Gene3D G3DSA:1.20.1250.20 235 432 9.9E-23 T 28-03-2018 SmaCSM2_RS06990 b54bd60b355dd20965aa24587e4abda0 433 Gene3D G3DSA:1.20.1250.20 13 230 2.0E-23 T 28-03-2018 SmaCSM2_RS06990 b54bd60b355dd20965aa24587e4abda0 433 SUPERFAMILY SSF103473 14 428 8.76E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06990 b54bd60b355dd20965aa24587e4abda0 433 Pfam PF00083 Sugar (and other) transporter 19 219 2.0E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 SUPERFAMILY SSF51735 12 195 5.92E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 12 416 3.2E-114 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 PIRSF PIRSF000124 12 424 2.3E-49 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Gene3D G3DSA:1.20.5.170 206 228 1.8E-10 T 28-03-2018 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Gene3D G3DSA:3.40.50.720 229 426 1.3E-52 T 28-03-2018 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 13 183 8.2E-32 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 PIRSF PIRSF500136 2 428 1.1E-143 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 419 4.3E-19 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 SUPERFAMILY SSF52413 316 423 4.84E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Gene3D G3DSA:3.40.50.720 3 202 2.4E-36 T 28-03-2018 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 SUPERFAMILY SSF48179 206 296 2.55E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 1.2E-24 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS07925 a1ba48fa2ad58f1dde8ba2f3ce69c3f9 428 SMART SM00984 322 421 1.4E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 Gene3D G3DSA:3.30.450.20 4 139 4.1E-15 T 28-03-2018 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 Pfam PF12833 Helix-turn-helix domain 153 229 1.3E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 SMART SM00342 145 227 1.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 SUPERFAMILY SSF46689 181 230 3.85E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 SUPERFAMILY SSF46689 128 178 6.27E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 182 223 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 Gene3D G3DSA:1.10.10.60 140 184 4.5E-10 T 28-03-2018 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 Pfam PF08448 PAS fold 12 120 5.0E-21 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 SUPERFAMILY SSF55785 8 117 1.03E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 Gene3D G3DSA:1.10.10.60 185 231 1.5E-12 T 28-03-2018 SmaCSM2_RS16080 194d893e791b88868db6e2a55d88f0d8 240 SMART SM00091 6 74 9.1E-5 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS14290 725c214d50c2a64c0ae55ae9e5370940 371 Pfam PF02353 Mycolic acid cyclopropane synthetase 101 356 1.7E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS14290 725c214d50c2a64c0ae55ae9e5370940 371 PIRSF PIRSF003085 5 365 1.8E-110 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SmaCSM2_RS14290 725c214d50c2a64c0ae55ae9e5370940 371 SUPERFAMILY SSF53335 106 358 6.69E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS14290 725c214d50c2a64c0ae55ae9e5370940 371 Gene3D G3DSA:3.40.50.150 95 360 2.5E-62 T 28-03-2018 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 Gene3D G3DSA:3.40.50.800 362 462 1.3E-19 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 Pfam PF03129 Anticodon binding domain 367 454 3.4E-13 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 Pfam PF13393 Histidyl-tRNA synthetase 10 348 1.3E-34 T 28-03-2018 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 460 28.458 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 PIRSF PIRSF001549 1 457 7.6E-139 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 Gene3D G3DSA:3.30.930.10 1 358 1.3E-86 T 28-03-2018 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 446 8.8E-121 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 SUPERFAMILY SSF55681 4 359 1.33E-71 T 28-03-2018 SmaCSM2_RS09520 1324d35d4dd34164ffed0bef02049601 465 SUPERFAMILY SSF52954 364 455 4.42E-21 T 28-03-2018 IPR004154 Anticodon-binding SmaCSM2_RS09955 90633a1359acc742b81a63530e83b335 74 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 4.8E-12 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 SmaCSM2_RS09955 90633a1359acc742b81a63530e83b335 74 SMART SM00966 3 48 1.0E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 SmaCSM2_RS09955 90633a1359acc742b81a63530e83b335 74 Gene3D G3DSA:2.10.260.10 2 46 1.4E-13 T 28-03-2018 SmaCSM2_RS09955 90633a1359acc742b81a63530e83b335 74 SUPERFAMILY SSF89447 2 43 1.1E-10 T 28-03-2018 SmaCSM2_RS09955 90633a1359acc742b81a63530e83b335 74 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 42 3.8E-9 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 Gene3D G3DSA:1.20.1600.10 29 480 1.2E-77 T 28-03-2018 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 SUPERFAMILY SSF56954 76 477 4.19E-90 T 28-03-2018 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 SUPERFAMILY SSF56954 2 40 4.19E-90 T 28-03-2018 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 Pfam PF02321 Outer membrane efflux protein 302 475 5.4E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 Pfam PF02321 Outer membrane efflux protein 85 269 2.9E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06810 d68ff9d5278a7e4329ff54194e68507c 480 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 22 477 4.5E-75 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 PIRSF PIRSF000388 1 271 2.2E-93 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 SUPERFAMILY SSF51621 10 269 1.88E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 11 264 6.3E-102 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 40.977 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 Gene3D G3DSA:3.20.20.60 1 269 3.8E-82 T 28-03-2018 SmaCSM2_RS08345 768feab01066b213d9dfdb050683a57e 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 16 269 7.6E-96 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 Gene3D G3DSA:3.40.50.450 2 235 2.6E-50 T 28-03-2018 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 398 44.152 T 28-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 33 46 3.4E-13 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 3.4E-13 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 234 246 3.4E-13 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 134 151 3.4E-13 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 192 3.4E-13 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 SUPERFAMILY SSF53784 7 414 1.16E-103 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 Pfam PF00365 Phosphofructokinase 10 322 9.6E-49 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SmaCSM2_RS17610 3b5247a9329b59060bcc63838624826c 418 PIRSF PIRSF036483 2 417 2.5E-208 T 28-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 SUPERFAMILY SSF53474 13 368 5.87E-91 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 Pfam PF00561 alpha/beta hydrolase fold 45 355 5.6E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 17 367 5.5E-111 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 2 369 44.745 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 Gene3D G3DSA:3.40.50.1820 25 370 2.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS14515 ac314efa798d3467638735b496412211 370 PIRSF PIRSF000443 1 370 2.2E-137 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 SUPERFAMILY SSF103473 12 368 2.35E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 97 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 Gene3D G3DSA:1.20.1250.20 258 600 4.7E-36 T 28-03-2018 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 SUPERFAMILY SSF103473 492 595 3.53E-14 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 Pfam PF00083 Sugar (and other) transporter 495 598 1.0E-21 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 Pfam PF00083 Sugar (and other) transporter 27 371 3.2E-65 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 Gene3D G3DSA:1.20.1250.20 12 241 1.4E-30 T 28-03-2018 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 PRINTS PR00171 Sugar transporter signature 499 520 6.4E-15 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 PRINTS PR00171 Sugar transporter signature 117 136 6.4E-15 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 PRINTS PR00171 Sugar transporter signature 522 534 6.4E-15 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 PRINTS PR00171 Sugar transporter signature 30 40 6.4E-15 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SmaCSM2_RS20610 4d552366ab67895aa49e8d436b19fafb 600 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 SMART SM00729 97 308 1.8E-15 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 TIGRFAM TIGR00510 lipA: lipoyl synthase 48 333 2.2E-132 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 Gene3D G3DSA:3.20.20.70 58 309 3.0E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 PIRSF PIRSF005963 1 335 1.8E-137 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 Hamap MF_00206 Lipoyl synthase [lipA]. 50 336 149.924 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 Pfam PF04055 Radical SAM superfamily 103 267 8.3E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 SUPERFAMILY SSF102114 66 331 3.66E-65 T 28-03-2018 SmaCSM2_RS18320 5cbc8105ca3938664040a0ed9ab9ff92 336 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 48 86 1.3E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SmaCSM2_RS11645 f3a3084fc8c6f8d94b315092a0784954 765 Gene3D G3DSA:2.170.130.10 40 184 6.8E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11645 f3a3084fc8c6f8d94b315092a0784954 765 Pfam PF00593 TonB dependent receptor 267 761 8.8E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11645 f3a3084fc8c6f8d94b315092a0784954 765 Gene3D G3DSA:2.40.170.20 185 765 1.7E-62 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS11645 f3a3084fc8c6f8d94b315092a0784954 765 SUPERFAMILY SSF56935 42 765 1.13E-104 T 28-03-2018 SmaCSM2_RS11645 f3a3084fc8c6f8d94b315092a0784954 765 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 175 1.9E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03055 c218889d7807346ef925b2425c96efa5 394 SUPERFAMILY SSF53756 2 370 1.02E-119 T 28-03-2018 SmaCSM2_RS03055 c218889d7807346ef925b2425c96efa5 394 Gene3D G3DSA:3.40.50.2000 210 354 1.5E-31 T 28-03-2018 SmaCSM2_RS03055 c218889d7807346ef925b2425c96efa5 394 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 368 8.4E-133 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 SmaCSM2_RS03055 c218889d7807346ef925b2425c96efa5 394 Gene3D G3DSA:3.40.50.2000 1 209 1.8E-64 T 28-03-2018 SmaCSM2_RS03055 c218889d7807346ef925b2425c96efa5 394 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 367 1.9E-109 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 121 200 1.0E-26 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 13 206 35.146 T 28-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 125 205 2.1E-12 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 115 201 18.422 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 SUPERFAMILY SSF101386 117 205 1.05E-21 T 28-03-2018 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 SUPERFAMILY SSF141734 14 114 3.79E-41 T 28-03-2018 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 110 1.0E-29 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 61 110 7.0E-17 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SmaCSM2_RS09570 06b26fc92a3e54b5c94ebdfa2abbe91b 206 Gene3D G3DSA:1.10.287.1080 114 206 7.1E-18 T 28-03-2018 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 748 765 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 Gene3D G3DSA:2.40.170.20 173 765 2.7E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 Gene3D G3DSA:2.170.130.10 32 172 9.4E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 Pfam PF00593 TonB dependent receptor 267 761 6.1E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 151 5.9E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 SUPERFAMILY SSF56935 302 765 4.45E-88 T 28-03-2018 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 SUPERFAMILY SSF56935 37 273 4.45E-88 T 28-03-2018 SmaCSM2_RS17920 2f61e6288998d19014a130cf9e43ca42 765 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 49 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 Gene3D G3DSA:2.30.40.10 44 109 2.3E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 Gene3D G3DSA:3.20.20.140 110 399 3.5E-24 T 28-03-2018 SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 SUPERFAMILY SSF51556 97 415 5.25E-30 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 Gene3D G3DSA:3.20.20.140 400 439 2.9E-7 T 28-03-2018 SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 Pfam PF01979 Amidohydrolase family 382 437 3.9E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 SUPERFAMILY SSF51338 35 98 2.84E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS17970 4a3431c870e3df919d3cebdb25570b9f 469 SUPERFAMILY SSF51338 414 452 2.84E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:3.10.196.10 749 894 2.4E-59 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 TIGRFAM TIGR02082 metH: methionine synthase 6 859 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:1.10.288.10 608 664 9.1E-26 T 28-03-2018 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 608 875 2.0E-121 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 SUPERFAMILY SSF51717 23 297 6.02E-88 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 SUPERFAMILY SSF56507 571 894 1.83E-128 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 PIRSF PIRSF000381 1 862 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 SMART SM01018 322 405 1.4E-43 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Pfam PF02607 B12 binding domain 324 397 1.3E-26 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:3.40.50.280 412 564 1.4E-55 T 28-03-2018 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Pfam PF02310 B12 binding domain 417 507 3.4E-20 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:1.10.288.10 680 748 4.8E-21 T 28-03-2018 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:3.20.20.20 13 310 2.1E-72 T 28-03-2018 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Gene3D G3DSA:1.10.1240.10 311 405 2.6E-36 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 Pfam PF00809 Pterin binding enzyme 27 265 2.5E-59 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 SUPERFAMILY SSF52242 411 563 2.62E-45 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SmaCSM2_RS14030 df85dc1da30658bb1c65fd601fefe793 894 SUPERFAMILY SSF47644 317 404 6.15E-28 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SMART SM00304 311 362 78.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SMART SM00304 401 453 42.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SMART SM00304 220 272 2.2E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 Pfam PF17200 Single Cache domain 2 46 193 1.1E-36 T 28-03-2018 IPR033480 Single Cache domain 2 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 514 668 4.0E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SUPERFAMILY SSF58104 421 702 1.96E-71 T 28-03-2018 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 Gene3D G3DSA:1.10.287.950 510 705 6.7E-48 T 28-03-2018 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 Gene3D G3DSA:1.10.287.950 226 509 9.1E-21 T 28-03-2018 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SMART SM00283 454 701 3.0E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 552 579 1.2E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 581 610 1.2E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 199 224 1.2E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 629 658 1.2E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 475 504 1.2E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SMART SM01049 43 138 1.1E-25 T 28-03-2018 IPR033480 Single Cache domain 2 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 SUPERFAMILY SSF158472 221 270 1.07E-6 T 28-03-2018 SmaCSM2_RS10000 03b7a7905e3b5889a4e4e0bf8b0a93e0 756 Gene3D G3DSA:3.30.450.20 40 197 8.0E-42 T 28-03-2018 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 Pfam PF00364 Biotin-requiring enzyme 85 158 3.0E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 115 132 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 Gene3D G3DSA:2.40.50.100 4 159 3.2E-20 T 28-03-2018 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 120 133 3.0E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 88 101 3.0E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 119 3.0E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 158 8.4E-52 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SmaCSM2_RS19330 3ea33a9876dc9d0e84882f568212f7e8 159 SUPERFAMILY SSF51230 84 158 3.4E-23 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 485 82.017 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 Gene3D G3DSA:3.20.20.70 1 481 6.5E-115 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 PIRSF PIRSF000130 1 485 1.7E-200 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 Pfam PF00571 CBS domain 95 139 3.7E-9 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 Pfam PF00571 CBS domain 149 201 7.8E-5 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SUPERFAMILY SSF51412 2 90 9.94E-125 T 28-03-2018 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SUPERFAMILY SSF51412 217 476 9.94E-125 T 28-03-2018 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SMART SM00116 158 206 6.8E-6 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SMART SM00116 96 144 6.2E-8 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 453 1.3E-187 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SMART SM01240 7 472 0.0 T 28-03-2018 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 SUPERFAMILY SSF54631 94 203 5.05E-27 T 28-03-2018 SmaCSM2_RS09090 403ff26387cf367fd2a2a97b4d1e56f2 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 472 3.0E-158 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SmaCSM2_RS09565 25f56877d79182b79abe66c7b706d963 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 255 43.224 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SmaCSM2_RS09565 25f56877d79182b79abe66c7b706d963 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 255 3.1E-99 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SmaCSM2_RS09565 25f56877d79182b79abe66c7b706d963 258 Gene3D G3DSA:3.20.20.70 4 251 6.1E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09565 25f56877d79182b79abe66c7b706d963 258 Pfam PF00977 Histidine biosynthesis protein 5 238 9.9E-71 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SmaCSM2_RS09565 25f56877d79182b79abe66c7b706d963 258 SUPERFAMILY SSF51366 1 255 1.18E-67 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Gene3D G3DSA:1.10.268.10 344 520 3.1E-53 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 870 0.0 T 28-03-2018 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 587 636 3.9E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 824 868 2.3E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 773 818 2.0E-15 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 644 686 4.1E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 737 2.2E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 537 583 4.3E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 872 24.172 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Gene3D G3DSA:2.120.10.90 532 887 3.8E-125 T 28-03-2018 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 505 3.0E-156 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 SMART SM00434 11 498 2.0E-285 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Gene3D G3DSA:3.90.199.10 34 214 8.7E-85 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 SUPERFAMILY SSF101904 532 739 8.24E-106 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 SUPERFAMILY SSF101904 771 881 8.24E-106 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 Gene3D G3DSA:3.30.1360.40 236 332 3.1E-37 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SmaCSM2_RS13845 fac3f150fc8fa3f9e4edf4138dffc761 908 SUPERFAMILY SSF56719 30 520 1.14E-180 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SmaCSM2_RS07575 f94d0d6734ad373aaf3a30da1c1a41a8 146 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 12 142 3.4E-53 T 28-03-2018 IPR022262 Lipoprotein, putative SmaCSM2_RS02980 cb7904d18d64e8fa638b5445889e39fe 139 Gene3D G3DSA:3.30.1300.30 32 132 4.9E-5 T 28-03-2018 SmaCSM2_RS02980 cb7904d18d64e8fa638b5445889e39fe 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 2.6E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02980 cb7904d18d64e8fa638b5445889e39fe 139 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02980 cb7904d18d64e8fa638b5445889e39fe 139 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 1.3E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02980 cb7904d18d64e8fa638b5445889e39fe 139 SUPERFAMILY SSF54523 8 89 3.77E-5 T 28-03-2018 SmaCSM2_RS19300 5fec953489ef37f8cd9a66b22acca030 198 SUPERFAMILY SSF52218 1 194 3.14E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS19300 5fec953489ef37f8cd9a66b22acca030 198 Gene3D G3DSA:3.40.50.360 1 196 3.2E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS19300 5fec953489ef37f8cd9a66b22acca030 198 Pfam PF02525 Flavodoxin-like fold 1 187 2.8E-41 T 28-03-2018 IPR003680 Flavodoxin-like fold SmaCSM2_RS20390 2444fce530ffad56ba9396cc529e9c9c 146 PIRSF PIRSF029509 1 146 3.9E-36 T 28-03-2018 IPR016923 Uncharacterised conserved protein UCP029509, membrane SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 Gene3D G3DSA:3.30.43.10 208 285 0.0021 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 Gene3D G3DSA:2.30.40.10 314 402 1.8E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 Pfam PF01979 Amidohydrolase family 290 383 2.4E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 SUPERFAMILY SSF51556 135 367 6.32E-6 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 SUPERFAMILY SSF51338 24 85 1.15E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 SUPERFAMILY SSF51338 366 412 1.15E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS17975 8c2f4c8182a4c526e4191be82dcd8272 420 Gene3D G3DSA:2.30.40.10 17 138 6.6E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 Gene3D G3DSA:1.10.520.20 2 104 6.8E-20 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 PRINTS PR00125 ATP synthase delta subunit signature 83 97 1.6E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 PRINTS PR00125 ATP synthase delta subunit signature 148 166 1.6E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 PRINTS PR00125 ATP synthase delta subunit signature 72 83 1.6E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.6E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 PRINTS PR00125 ATP synthase delta subunit signature 133 148 1.6E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 173 1.9E-45 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 SUPERFAMILY SSF47928 3 103 1.83E-18 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 175 18.321 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18705 f86284480e5bea7d40679f5163c1f14c 175 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 173 6.8E-33 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Gene3D G3DSA:2.130.10.120 551 744 3.1E-8 T 28-03-2018 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Gene3D G3DSA:1.10.10.10 9 121 3.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 SMART SM00862 34 110 2.1E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Gene3D G3DSA:2.130.10.150 375 550 1.0E-25 T 28-03-2018 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 SUPERFAMILY SSF46894 12 112 1.62E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Pfam PF00486 Transcriptional regulatory protein, C terminal 37 110 1.5E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Gene3D G3DSA:2.140.10.30 188 374 4.2E-24 T 28-03-2018 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Pfam PF07676 WD40-like Beta Propeller Repeat 485 520 6.5E-8 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Pfam PF07676 WD40-like Beta Propeller Repeat 270 294 0.016 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Pfam PF07676 WD40-like Beta Propeller Repeat 365 386 3.9E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 Pfam PF07676 WD40-like Beta Propeller Repeat 213 235 0.001 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 SUPERFAMILY SSF82171 214 523 6.02E-37 T 28-03-2018 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 SUPERFAMILY SSF82171 500 568 1.02E-9 T 28-03-2018 SmaCSM2_RS17715 6aa535ea2c43c29027eaffc690969ea3 774 SUPERFAMILY SSF82171 610 696 1.02E-9 T 28-03-2018 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 SUPERFAMILY SSF56808 5 225 7.98E-74 T 28-03-2018 IPR023674 Ribosomal protein L1-like SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 Gene3D G3DSA:3.40.50.790 67 150 1.2E-30 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 PIRSF PIRSF002155 1 227 2.8E-70 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 40.165 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 Gene3D G3DSA:3.30.190.20 151 228 2.9E-20 T 28-03-2018 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 8.3E-99 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SmaCSM2_RS03935 8d2743795282d7f1b43c4d0a6eb48e04 232 Pfam PF00687 Ribosomal protein L1p/L10e family 29 220 6.2E-45 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SmaCSM2_RS20885 7da0b2996c63d5968ab468d102fd8d3f 248 Pfam PF00005 ABC transporter 22 165 6.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS20885 7da0b2996c63d5968ab468d102fd8d3f 248 SMART SM00382 30 221 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS20885 7da0b2996c63d5968ab468d102fd8d3f 248 SUPERFAMILY SSF52540 2 226 7.28E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20885 7da0b2996c63d5968ab468d102fd8d3f 248 Gene3D G3DSA:3.40.50.300 1 243 5.1E-63 T 28-03-2018 SmaCSM2_RS08060 7840e3163663eb0f3c280173413b816d 259 Pfam PF01975 Survival protein SurE 3 185 1.9E-61 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 SmaCSM2_RS08060 7840e3163663eb0f3c280173413b816d 259 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 253 41.7 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 SmaCSM2_RS08060 7840e3163663eb0f3c280173413b816d 259 Gene3D G3DSA:3.40.1210.10 1 257 4.0E-89 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 SmaCSM2_RS08060 7840e3163663eb0f3c280173413b816d 259 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 236 8.2E-71 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 SmaCSM2_RS08060 7840e3163663eb0f3c280173413b816d 259 SUPERFAMILY SSF64167 1 249 3.14E-84 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Gene3D G3DSA:3.30.43.10 8 81 2.2E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Gene3D G3DSA:3.30.465.10 85 237 7.8E-45 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 20 350 9.0E-67 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 225 348 1.4E-32 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 353 80.92 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 SUPERFAMILY SSF56194 222 351 8.5E-44 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 SUPERFAMILY SSF56176 20 205 5.4E-34 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Pfam PF01565 FAD binding domain 38 158 4.0E-16 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS09355 749c358222161b5ec9a35ca1625ad4ca 353 Gene3D G3DSA:3.90.78.10 240 353 5.4E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS11715 5512cf9d2c86ff4189ca81016a8ff7a7 194 SUPERFAMILY SSF46689 14 74 2.51E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11715 5512cf9d2c86ff4189ca81016a8ff7a7 194 Gene3D G3DSA:1.10.357.10 5 188 3.7E-18 T 28-03-2018 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 SUPERFAMILY SSF48498 79 184 4.89E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 Gene3D G3DSA:1.10.357.10 56 185 9.5E-28 T 28-03-2018 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 9.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 SUPERFAMILY SSF46689 4 83 4.31E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11200 4cfab6383eaa85a07b838106cdd53989 189 Gene3D G3DSA:1.10.10.60 2 55 5.3E-13 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:3.30.70.1440 668 764 2.5E-16 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82714 720 802 1.83E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82714 183 272 5.23E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:3.30.70.1430 567 667 1.5E-15 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:3.30.2090.10 180 275 1.6E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82866 296 498 1.57E-47 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:1.20.1640.10 276 499 4.7E-44 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:1.20.1640.10 823 1023 1.9E-39 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 565 665 2.3E-22 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 668 717 9.94E-21 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 804 852 9.94E-21 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1023 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 5.4E-95 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 38 130 1.88E-21 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82866 828 1020 2.62E-45 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1021 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 Gene3D G3DSA:3.30.70.1430 38 140 5.6E-23 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 274 329 1.92E-22 T 28-03-2018 SmaCSM2_RS09740 82509f9744ccb2356d20bd31a27b5c75 1049 SUPERFAMILY SSF82693 135 182 1.92E-22 T 28-03-2018 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 SUPERFAMILY SSF56801 11 536 2.49E-130 T 28-03-2018 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Gene3D G3DSA:3.30.300.30 433 543 3.7E-21 T 28-03-2018 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 527 2.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Gene3D G3DSA:3.40.50.980 11 183 4.3E-31 T 28-03-2018 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 28-03-2018 IPR020845 AMP-binding, conserved site SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Gene3D G3DSA:3.40.50.980 184 345 6.8E-40 T 28-03-2018 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Pfam PF00501 AMP-binding enzyme 24 438 6.7E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SmaCSM2_RS11445 51bc4db52051e30e9b33db19e6fd9dc3 546 Gene3D G3DSA:2.30.38.10 355 432 1.4E-19 T 28-03-2018 SmaCSM2_RS10705 8aa9cbd50c21cbed6535ce428e07b517 258 SUPERFAMILY SSF55073 5 141 4.4E-6 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS10705 8aa9cbd50c21cbed6535ce428e07b517 258 Gene3D G3DSA:3.30.70.1230 3 178 1.4E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 440 9.1E-63 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Gene3D G3DSA:1.20.272.10 258 352 1.1E-36 T 28-03-2018 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 SUPERFAMILY SSF48019 258 440 2.08E-69 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Gene3D G3DSA:3.40.50.300 15 162 6.0E-29 T 28-03-2018 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 SUPERFAMILY SSF52540 20 236 1.15E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Gene3D G3DSA:1.10.3710.10 354 453 1.8E-32 T 28-03-2018 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 62 170 1.7E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Gene3D G3DSA:1.10.8.60 163 249 1.8E-20 T 28-03-2018 SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 Pfam PF16193 AAA C-terminal domain 197 273 1.7E-21 T 28-03-2018 IPR032423 AAA C-terminal domain SmaCSM2_RS10460 5c1e024fa7dd5e90c5c564fa7e8e99c7 453 SMART SM00382 58 174 6.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS05255 0b0f269e8281f8ae06c8d5cc09f50713 212 Pfam PF16357 Putative PepSY_TM-like 17 212 1.3E-84 T 28-03-2018 IPR032307 Putative PepSY TM-like protein SmaCSM2_RS18385 0d12b24917d22e517cfd0990917bc77d 312 SUPERFAMILY SSF53613 2 297 4.37E-65 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS18385 0d12b24917d22e517cfd0990917bc77d 312 Pfam PF00294 pfkB family carbohydrate kinase 36 290 5.9E-35 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SmaCSM2_RS18385 0d12b24917d22e517cfd0990917bc77d 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SmaCSM2_RS18385 0d12b24917d22e517cfd0990917bc77d 312 Gene3D G3DSA:3.40.1190.20 1 308 6.9E-49 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 Pfam PF08479 POTRA domain, ShlB-type 82 161 2.5E-21 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 Pfam PF17287 POTRA domain 162 216 3.6E-16 T 28-03-2018 IPR035251 ShlB, POTRA domain SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 Gene3D G3DSA:3.10.20.310 95 161 6.3E-10 T 28-03-2018 SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 PIRSF PIRSF029745 10 574 4.7E-145 T 28-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 Gene3D G3DSA:2.40.160.50 189 574 7.8E-55 T 28-03-2018 SmaCSM2_RS00635 41d10dbfff645f622f8e76760bb36592 574 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 226 538 7.2E-108 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal SmaCSM2_RS01090 ea967ae694d36bed97a18d6fa025baf4 215 Pfam PF06551 Protein of unknown function (DUF1120) 31 105 4.4E-7 T 28-03-2018 IPR010546 Protein of unknown function DUF1120 SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 SUPERFAMILY SSF52540 209 280 7.87E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 SUPERFAMILY SSF52540 307 459 7.87E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 Pfam PF00772 DnaB-like helicase N terminal domain 33 134 3.2E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 Pfam PF03796 DnaB-like helicase C terminal domain 211 466 5.3E-118 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 Gene3D G3DSA:3.40.50.300 193 474 2.7E-71 T 28-03-2018 SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 SUPERFAMILY SSF48024 31 142 2.88E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 Gene3D G3DSA:1.10.860.10 23 175 7.6E-47 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SmaCSM2_RS14165 64e3ceb6ca8c3496dd40c734a6350c55 476 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 33 468 1.3E-178 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 298 6.8E-73 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 SUPERFAMILY SSF56059 124 311 2.94E-54 T 28-03-2018 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Gene3D G3DSA:3.40.50.20 3 130 7.6E-42 T 28-03-2018 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Hamap MF_00162 Glutathione synthetase [gshB]. 1 315 156.303 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 SUPERFAMILY SSF52440 3 123 1.76E-38 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Gene3D G3DSA:3.30.1490.20 139 192 4.2E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Gene3D G3DSA:3.30.470.20 193 301 4.2E-14 T 28-03-2018 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 312 2.1E-135 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SmaCSM2_RS16500 d8d03ec42aa2d39ec8dffefa288697c4 315 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 1.5E-38 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 Pfam PF08245 Mur ligase middle domain 49 217 6.9E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 SUPERFAMILY SSF53244 286 420 1.83E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 Gene3D G3DSA:3.40.1190.10 1 290 7.2E-76 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 TIGRFAM TIGR01499 folC: bifunctional protein FolC 27 418 3.7E-98 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 PIRSF PIRSF001563 2 423 6.4E-102 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 SUPERFAMILY SSF53623 6 284 1.57E-86 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS04260 78e205e56d2e6e3cb267e67f09f9961a 423 Gene3D G3DSA:3.90.190.20 291 423 7.0E-24 T 28-03-2018 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 Pfam PF01494 FAD binding domain 10 168 6.7E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 2.9E-5 T 28-03-2018 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 2.9E-5 T 28-03-2018 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 266 2.9E-5 T 28-03-2018 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 SUPERFAMILY SSF51905 289 391 2.29E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 SUPERFAMILY SSF51905 9 179 2.29E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS21085 f2d0d858fe2868ae0d9fb0e064a99468 416 Gene3D G3DSA:3.50.50.60 6 330 7.0E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07625 163aa526559e547def9ee368da8fb84b 179 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 75 179 2.8E-41 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 SmaCSM2_RS07625 163aa526559e547def9ee368da8fb84b 179 Pfam PF11072 Protein of unknown function (DUF2859) 31 177 1.9E-53 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 16 277 3.6E-85 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 SUPERFAMILY SSF51690 114 278 7.46E-54 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 25 111 5.0E-21 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 Gene3D G3DSA:3.90.1170.20 3 138 1.3E-40 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 SUPERFAMILY SSF54675 12 112 8.24E-28 T 28-03-2018 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 PIRSF PIRSF006250 9 280 8.7E-87 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 277 3.4E-50 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS07170 835f8be465ce86c4bd6066628cf85991 283 Gene3D G3DSA:3.20.20.70 139 268 4.5E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 645 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 666 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 358 372 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 524 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 728 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 732 744 2.0E-28 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 512 518 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF81653 312 408 4.18E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Gene3D G3DSA:3.30.70.100 13 79 5.4E-21 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 ProSitePatterns PS01047 Heavy-metal-associated domain. 87 116 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 ProSitePatterns PS01047 Heavy-metal-associated domain. 20 49 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Pfam PF00122 E1-E2 ATPase 309 489 3.7E-56 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 17 78 6.0E-12 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 83 143 2.4E-10 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF55008 82 147 3.8E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 241 818 1.7E-189 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Gene3D G3DSA:3.30.70.100 81 149 1.3E-24 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF81665 273 312 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF81665 409 504 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF81665 758 797 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 223 819 2.1E-181 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Pfam PF00702 haloacid dehalogenase-like hydrolase 508 723 6.5E-44 T 28-03-2018 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Pfam PF00403 Heavy-metal-associated domain 18 77 4.6E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Pfam PF00403 Heavy-metal-associated domain 85 142 3.1E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 280 787 3.4E-93 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Gene3D G3DSA:3.40.50.1000 635 775 7.9E-47 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 681 697 8.2E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 740 765 8.2E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 587 605 8.2E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 709 725 8.2E-11 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF56784 567 816 8.76E-60 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF56784 508 528 8.76E-60 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Gene3D G3DSA:3.40.1110.10 525 634 3.7E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 SUPERFAMILY SSF55008 10 78 1.44E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS09610 837e54a8a99bc61ff60d73aa5c32201d 833 Gene3D G3DSA:1.20.1110.10 273 524 8.7E-49 T 28-03-2018 SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 SUPERFAMILY SSF50249 1 78 3.77E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 Gene3D G3DSA:2.40.50.140 2 78 2.9E-20 T 28-03-2018 SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 Pfam PF11967 Recombination protein O N terminal 2 78 5.9E-18 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 Hamap MF_00201 DNA repair protein RecO [recO]. 2 235 19.333 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 154 8.0E-19 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SmaCSM2_RS15930 61628cffc36048afc6efc11406915d93 239 Pfam PF02565 Recombination protein O C terminal 85 230 9.7E-16 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 Gene3D G3DSA:3.40.50.620 1 208 1.2E-61 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 357 5.9E-127 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 Gene3D G3DSA:2.40.30.10 279 369 9.6E-30 T 28-03-2018 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 358 37.707 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 Pfam PF03054 tRNA methyl transferase 5 357 7.6E-128 T 28-03-2018 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 Gene3D G3DSA:2.30.30.280 209 276 5.1E-22 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 SmaCSM2_RS10370 522cc49dac74c87ffb05d1c7465be317 380 SUPERFAMILY SSF52402 3 241 1.04E-49 T 28-03-2018 SmaCSM2_RS13285 7786add071e3b452f7718adf205a3ea7 169 Pfam PF06853 Protein of unknown function (DUF1249) 31 145 4.8E-26 T 28-03-2018 IPR009659 Protein of unknown function DUF1249 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 SUPERFAMILY SSF54523 41 143 2.56E-35 T 28-03-2018 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 50 68 1.1E-17 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 14 39 1.1E-17 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 Gene3D G3DSA:3.30.700.10 28 143 7.1E-28 T 28-03-2018 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 13 144 3.4E-52 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 1.2E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 4.5E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12185 cea7edc7ad712bc7453a2172eae4ee5c 145 Pfam PF08334 Type II secretion system (T2SS), protein G 37 143 4.2E-40 T 28-03-2018 IPR013545 Type II secretion system protein G SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 PRINTS PR00113 Alkaline phosphatase signature 124 139 2.8E-39 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 PRINTS PR00113 Alkaline phosphatase signature 68 88 2.8E-39 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 PRINTS PR00113 Alkaline phosphatase signature 170 190 2.8E-39 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 PRINTS PR00113 Alkaline phosphatase signature 233 243 2.8E-39 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 PRINTS PR00113 Alkaline phosphatase signature 321 350 2.8E-39 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 SMART SM00098 69 536 9.7E-137 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 SUPERFAMILY SSF53649 59 533 1.74E-139 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 Pfam PF00245 Alkaline phosphatase 68 532 6.3E-120 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS15510 5857bd15cc983361588b97c9f39624fc 568 Gene3D G3DSA:3.40.720.10 32 538 9.0E-139 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS05355 db4afb352373cb5bb8a018d9e6040d3e 132 SMART SM00411 35 132 2.9E-10 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS05355 db4afb352373cb5bb8a018d9e6040d3e 132 Pfam PF00216 Bacterial DNA-binding protein 35 130 6.4E-16 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS05355 db4afb352373cb5bb8a018d9e6040d3e 132 SUPERFAMILY SSF47729 35 130 7.8E-14 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS05355 db4afb352373cb5bb8a018d9e6040d3e 132 Gene3D G3DSA:4.10.520.10 35 131 1.9E-17 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS03320 a07689f5c6038e5288e3d6643e57b851 275 Pfam PF02219 Methylenetetrahydrofolate reductase 2 272 1.0E-86 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SmaCSM2_RS03320 a07689f5c6038e5288e3d6643e57b851 275 Gene3D G3DSA:3.20.20.220 1 274 8.6E-93 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS03320 a07689f5c6038e5288e3d6643e57b851 275 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 4 273 3.7E-100 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SmaCSM2_RS03320 a07689f5c6038e5288e3d6643e57b851 275 SUPERFAMILY SSF51730 3 273 1.61E-90 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 206 254 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 SUPERFAMILY SSF49503 131 275 1.64E-54 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 Gene3D G3DSA:2.60.40.420 125 306 2.4E-51 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 SUPERFAMILY SSF81464 28 127 6.7E-24 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 117 1.3E-14 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 57 270 2.1E-62 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 Gene3D G3DSA:1.10.287.90 35 124 3.7E-24 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 133 261 5.5E-40 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 205 225 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 107 127 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 181 202 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 95 107 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 242 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 129 148 1.6E-43 T 28-03-2018 SmaCSM2_RS01780 f6073b77b2eec80e9c24c20a87cf359d 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 243 260 1.6E-43 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 603 613 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 599 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 640 653 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 616 634 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF52172 678 795 1.04E-28 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00448 11 123 2.1E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00448 678 790 1.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:3.40.50.2300 674 799 8.1E-29 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 534 654 4.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF52172 10 170 1.99E-23 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF00072 Response regulator receiver domain 680 791 6.2E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF00072 Response regulator receiver domain 13 123 3.0E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:1.10.287.130 414 488 8.6E-7 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF55874 483 654 4.06E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00388 422 492 8.7E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00387 533 656 1.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF47384 412 489 7.85E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00091 148 214 0.012 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SMART SM00091 291 357 29.0 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF08448 PAS fold 155 261 2.1E-19 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF08448 PAS fold 305 407 2.0E-8 T 28-03-2018 IPR013656 PAS fold-4 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:3.30.565.10 491 656 1.0E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:3.30.450.20 140 276 9.2E-32 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:3.30.450.20 277 413 3.7E-18 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Pfam PF00512 His Kinase A (phospho-acceptor) domain 423 490 4.9E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF55785 282 398 1.86E-7 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 145 268 3.9E-11 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 Gene3D G3DSA:3.40.50.2300 1 139 1.7E-22 T 28-03-2018 SmaCSM2_RS10595 6c6c4943e74fe47ece94ec5ec96a4444 799 SUPERFAMILY SSF55785 134 259 2.62E-21 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 893 1000 3.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SUPERFAMILY SSF55874 838 1001 2.23E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SMART SM00388 782 848 3.8E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Gene3D G3DSA:1.10.287.130 787 842 4.9E-11 T 28-03-2018 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SMART SM00387 892 1003 6.0E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 635 758 4.4E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Gene3D G3DSA:3.40.50.2300 1019 1148 8.1E-21 T 28-03-2018 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SMART SM00091 636 704 3.0E-4 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Pfam PF00512 His Kinase A (phospho-acceptor) domain 782 848 1.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SMART SM00448 1030 1141 7.5E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SUPERFAMILY SSF52172 1029 1144 3.27E-20 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SUPERFAMILY SSF55785 627 749 1.17E-10 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 SUPERFAMILY SSF47384 766 849 2.35E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Pfam PF12860 PAS fold 642 756 5.4E-43 T 28-03-2018 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Gene3D G3DSA:3.30.565.10 843 1003 8.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Pfam PF00072 Response regulator receiver domain 1032 1139 3.3E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 928 942 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 946 956 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 987 1000 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 963 981 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS21400 6a9294e18c61ca0dcd8612ef37d8cfb2 1148 Gene3D G3DSA:3.30.450.20 633 786 1.6E-21 T 28-03-2018 SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 186 347 7.6E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 SMART SM00267 179 349 8.6E-59 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 345 1.1E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 SUPERFAMILY SSF55073 197 346 4.97E-43 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 Gene3D G3DSA:3.30.70.270 173 349 8.9E-54 T 28-03-2018 SmaCSM2_RS05525 d23a5b6db3a6f03a9dd057324331dd56 350 Pfam PF05230 MASE2 domain 20 107 4.0E-26 T 28-03-2018 IPR007894 MASE2 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 SUPERFAMILY SSF52540 64 407 3.53E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 SMART SM01086 319 414 8.9E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Gene3D G3DSA:3.40.50.300 58 317 1.0E-72 T 28-03-2018 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 SMART SM00994 15 54 3.7E-24 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 312 5.0E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 397 8.5E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 SMART SM00382 113 266 6.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Gene3D G3DSA:1.10.8.60 319 411 4.4E-33 T 28-03-2018 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 9 417 53.384 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 Pfam PF06689 ClpX C4-type zinc finger 16 53 2.2E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 SUPERFAMILY SSF57716 16 51 9.27E-12 T 28-03-2018 SmaCSM2_RS04425 f7e96ba35eaa19470665deeed5da8af4 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 14 414 8.3E-207 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 Pfam PF00035 Double-stranded RNA binding motif 156 223 6.4E-13 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 SMART SM00535 20 148 2.2E-49 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 SMART SM00358 156 224 1.2E-20 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 220 28.26 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 12 223 4.6E-72 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 SUPERFAMILY SSF54768 108 223 6.76E-28 T 28-03-2018 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 SUPERFAMILY SSF69065 10 158 3.84E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 Gene3D G3DSA:1.10.1520.10 6 148 2.1E-39 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 Pfam PF14622 Ribonuclease-III-like 18 138 1.3E-32 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 Gene3D G3DSA:3.30.160.20 155 226 1.1E-21 T 28-03-2018 SmaCSM2_RS15940 8b91df9c9f60e05eaa255538c2422fd0 226 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SmaCSM2_RS13675 a9fe34060158c79bb6bc774eac69072a 60 SUPERFAMILY SSF54786 1 60 1.49E-16 T 28-03-2018 SmaCSM2_RS13675 a9fe34060158c79bb6bc774eac69072a 60 Gene3D G3DSA:3.30.920.30 1 59 2.7E-19 T 28-03-2018 SmaCSM2_RS13675 a9fe34060158c79bb6bc774eac69072a 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 59 2.4E-16 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 SMART SM00342 284 369 5.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 321 365 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 Gene3D G3DSA:1.10.10.60 260 317 6.0E-5 T 28-03-2018 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 338 353 4.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 353 369 4.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 Gene3D G3DSA:1.10.10.60 318 373 8.8E-12 T 28-03-2018 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 Pfam PF12833 Helix-turn-helix domain 290 370 7.0E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS20515 006233830374f0ee3f831c5dce626af5 375 SUPERFAMILY SSF46689 321 370 5.38E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS02530 015d8b8c9a97db858e616e1215f03928 160 Pfam PF13185 GAF domain 54 155 1.8E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS02530 015d8b8c9a97db858e616e1215f03928 160 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site SmaCSM2_RS02530 015d8b8c9a97db858e616e1215f03928 160 Gene3D G3DSA:3.30.450.40 10 160 2.5E-27 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS02530 015d8b8c9a97db858e616e1215f03928 160 SUPERFAMILY SSF55781 12 159 8.29E-43 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Gene3D G3DSA:3.10.20.30 384 459 7.6E-22 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 SMART SM00954 238 348 7.2E-67 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Gene3D G3DSA:3.30.460.10 195 328 5.3E-43 T 28-03-2018 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Pfam PF02824 TGS domain 393 449 1.3E-18 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 SUPERFAMILY SSF109604 47 193 1.88E-23 T 28-03-2018 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Pfam PF04607 Region found in RelA / SpoT proteins 238 348 3.3E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 SUPERFAMILY SSF81301 195 367 5.89E-63 T 28-03-2018 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Pfam PF13328 HD domain 54 179 4.7E-18 T 28-03-2018 IPR003607 HD/PDEase domain SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 56 713 9.8E-164 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 SUPERFAMILY SSF81271 385 449 2.62E-19 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 SUPERFAMILY SSF55021 641 716 4.22E-8 T 28-03-2018 SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Pfam PF13291 ACT domain 639 716 2.6E-16 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS16540 18bd4a819b94684a314c5feeb8735409 718 Gene3D G3DSA:3.30.70.260 638 718 4.2E-8 T 28-03-2018 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 502 657 2.2E-49 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 Gene3D G3DSA:3.30.450.20 213 352 1.8E-12 T 28-03-2018 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 SMART SM00283 443 690 1.6E-89 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 Gene3D G3DSA:3.90.20.10 353 505 7.9E-6 T 28-03-2018 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 541 568 1.8E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 570 599 1.8E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 464 493 1.8E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 618 647 1.8E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 SUPERFAMILY SSF58104 410 691 1.7E-67 T 28-03-2018 SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 SUPERFAMILY SSF55785 218 342 8.07E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS21485 fc4529422b8b1948ceb041d4f7561322 701 Gene3D G3DSA:1.10.287.950 506 694 2.3E-48 T 28-03-2018 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 Gene3D G3DSA:3.40.50.620 196 522 8.2E-86 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 SUPERFAMILY SSF52402 212 487 7.82E-74 T 28-03-2018 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 SUPERFAMILY SSF56235 1 199 9.44E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 Gene3D G3DSA:3.60.20.10 2 195 1.7E-46 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 Pfam PF00733 Asparagine synthase 215 371 5.6E-57 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 SMART SM01172 53 236 8.6E-4 T 28-03-2018 IPR024286 Domain of unknown function DUF3700 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 375 2.0E-107 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 PIRSF PIRSF001589 365 524 1.1E-29 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 PIRSF PIRSF001589 1 371 9.9E-107 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SmaCSM2_RS06720 b4ad054e31b2bd7a443ef17763e422d1 563 Pfam PF13537 Glutamine amidotransferase domain 50 170 6.4E-39 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SmaCSM2_RS02255 215e5a63610e117fe4133d0dc9546fa9 137 Pfam PF03795 YCII-related domain 1 111 5.3E-17 T 28-03-2018 IPR005545 YCII-related SmaCSM2_RS02255 215e5a63610e117fe4133d0dc9546fa9 137 SUPERFAMILY SSF54909 1 115 1.66E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS02255 215e5a63610e117fe4133d0dc9546fa9 137 Gene3D G3DSA:3.30.70.1060 1 116 1.1E-30 T 28-03-2018 SmaCSM2_RS02905 517a772e6b2fb18c8bab937ed16dadfb 360 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 348 8.0E-74 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 SmaCSM2_RS02905 517a772e6b2fb18c8bab937ed16dadfb 360 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 4 348 5.5E-109 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 Gene3D G3DSA:1.10.10.10 2 84 2.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 SUPERFAMILY SSF53850 88 293 5.89E-36 T 28-03-2018 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 Gene3D G3DSA:3.40.190.10 181 267 3.5E-15 T 28-03-2018 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.8E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 SUPERFAMILY SSF46785 6 111 8.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 Pfam PF03466 LysR substrate binding domain 88 292 4.2E-35 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11380 c06ad23c63d19d0231b2ff9feaa62b94 304 Gene3D G3DSA:3.40.190.10 91 180 6.7E-15 T 28-03-2018 SmaCSM2_RS10320 9f8ff544c0b1df7ffcccdb206ca909c8 112 SUPERFAMILY SSF140566 7 83 2.35E-5 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 SmaCSM2_RS10320 9f8ff544c0b1df7ffcccdb206ca909c8 112 Gene3D G3DSA:1.20.58.300 54 86 0.22 T 28-03-2018 SmaCSM2_RS10320 9f8ff544c0b1df7ffcccdb206ca909c8 112 Gene3D G3DSA:1.20.58.300 2 48 0.0016 T 28-03-2018 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 Gene3D G3DSA:2.40.150.20 1 122 3.0E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 SMART SM01374 1 122 6.1E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 SUPERFAMILY SSF50193 1 122 2.75E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.556 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 6.5E-55 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04040 c85e2c393b1a8db40d750e1fcef247f1 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-58 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SmaCSM2_RS20215 fba5ebc05b65b02da28077cf319aa2b2 202 SUPERFAMILY SSF55729 19 139 2.84E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS20215 fba5ebc05b65b02da28077cf319aa2b2 202 Gene3D G3DSA:3.40.630.30 13 195 4.9E-13 T 28-03-2018 SmaCSM2_RS20215 fba5ebc05b65b02da28077cf319aa2b2 202 Pfam PF00583 Acetyltransferase (GNAT) family 38 133 3.2E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 SUPERFAMILY SSF51197 2 307 1.17E-86 T 28-03-2018 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 4 121 1.7E-32 T 28-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 172 270 3.1E-15 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 PRINTS PR00682 Isopenicillin N synthase signature 23 40 9.7E-9 T 28-03-2018 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 PRINTS PR00682 Isopenicillin N synthase signature 190 211 9.7E-9 T 28-03-2018 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 PRINTS PR00682 Isopenicillin N synthase signature 226 252 9.7E-9 T 28-03-2018 SmaCSM2_RS15195 0ef9db06e38cc0f5d9c361041ca8a708 311 Gene3D G3DSA:2.60.120.330 1 311 4.2E-91 T 28-03-2018 IPR027443 Isopenicillin N synthase-like SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 213 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 329 349 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 144 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 295 312 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 274 293 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 264 4.9E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 Gene3D G3DSA:3.40.50.720 74 367 8.0E-72 T 28-03-2018 SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 261 289 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 SUPERFAMILY SSF51735 124 365 8.27E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 274 293 8.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 202 213 8.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 254 262 8.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS00430 162f16c0c6784eb76f1d451814f844c4 368 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 135 365 5.3E-53 T 28-03-2018 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 SUPERFAMILY SSF56655 5 262 8.51E-78 T 28-03-2018 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 210 224 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 Pfam PF00459 Inositol monophosphatase family 4 254 1.2E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 155 181 1.5E-17 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 103 122 1.5E-17 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 197 209 1.5E-17 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 18 40 1.5E-17 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 7.8E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 Gene3D G3DSA:3.40.190.80 145 274 2.3E-35 T 28-03-2018 SmaCSM2_RS14720 d9a3d0696a076a90604f198a548971d8 275 Gene3D G3DSA:3.30.540.10 3 144 6.8E-43 T 28-03-2018 SmaCSM2_RS15915 84b2f0e791b6edc398912fbec9a4292c 161 PIRSF PIRSF016487 1 161 1.9E-60 T 28-03-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like SmaCSM2_RS15915 84b2f0e791b6edc398912fbec9a4292c 161 Gene3D G3DSA:2.40.320.10 1 159 1.4E-37 T 28-03-2018 SmaCSM2_RS15915 84b2f0e791b6edc398912fbec9a4292c 161 SMART SM01118 2 155 2.8E-20 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SmaCSM2_RS15915 84b2f0e791b6edc398912fbec9a4292c 161 Pfam PF01928 CYTH domain 3 145 7.3E-16 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SmaCSM2_RS15915 84b2f0e791b6edc398912fbec9a4292c 161 SUPERFAMILY SSF55154 1 155 2.78E-38 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 Pfam PF00929 Exonuclease 4 164 5.4E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 SUPERFAMILY SSF53098 1 176 2.28E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 233 4.0E-94 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 177 2.2E-58 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 SMART SM00479 2 175 3.7E-43 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS04490 936f6bb3020a27c7cae1b55ac783a5ae 243 Gene3D G3DSA:3.30.420.10 2 177 3.7E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 SUPERFAMILY SSF46785 4 87 2.06E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 Gene3D G3DSA:1.10.10.10 1 85 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 SUPERFAMILY SSF53850 88 283 4.16E-16 T 28-03-2018 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 Pfam PF03466 LysR substrate binding domain 87 282 4.4E-14 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 Gene3D G3DSA:3.40.190.10 86 196 3.4E-10 T 28-03-2018 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07430 09e535b35d5953765de49adfd6f20a20 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 7.6E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:3.30.2090.10 710 832 8.7E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 613 627 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 2.7E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82714 181 264 2.88E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82693 559 654 5.49E-13 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:3.30.2090.10 179 266 2.3E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:3.30.70.1430 561 659 7.1E-14 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82693 136 180 2.93E-23 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82693 266 322 2.93E-23 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:1.20.1640.10 279 500 1.1E-48 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:1.20.1640.10 845 1066 2.5E-35 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82866 288 489 1.7E-48 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82693 40 131 1.74E-21 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Pfam PF00873 AcrB/AcrD/AcrF family 4 1051 1.5E-299 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 Gene3D G3DSA:3.30.70.1430 40 140 2.6E-23 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82866 833 1057 7.98E-45 T 28-03-2018 SmaCSM2_RS19545 dbfbfa63b655aa9c11b631373276f7c0 1077 SUPERFAMILY SSF82714 710 779 1.7E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 196 100.081 T 28-03-2018 IPR017757 Transcriptional repressor BetI SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 191 9.8E-36 T 28-03-2018 SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 191 1.5E-73 T 28-03-2018 IPR017757 Transcriptional repressor BetI SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 SUPERFAMILY SSF48498 80 192 5.82E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 SUPERFAMILY SSF46689 6 80 1.28E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 Gene3D G3DSA:1.10.357.10 62 195 6.6E-18 T 28-03-2018 SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 Gene3D G3DSA:1.10.10.60 6 61 1.2E-14 T 28-03-2018 SmaCSM2_RS09935 4524e7f0fe4841e420dd414163e151b5 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 SMART SM00825 Beta-ketoacyl synthase 5 420 9.3E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 Gene3D G3DSA:3.40.47.10 5 268 9.5E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 PIRSF PIRSF000447 1 420 6.3E-174 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 SUPERFAMILY SSF53901 2 260 4.15E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 377 2.2E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 418 9.1E-186 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 163 179 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 SUPERFAMILY SSF53901 223 419 1.14E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 255 2.9E-56 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SmaCSM2_RS04810 b436d70b4a33618d2f824b41a34dd76d 420 Gene3D G3DSA:3.40.47.10 271 420 1.4E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 SUPERFAMILY SSF46689 207 255 6.27E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 SUPERFAMILY SSF51182 14 137 8.01E-9 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 Gene3D G3DSA:2.60.120.280 23 165 1.4E-8 T 28-03-2018 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 Pfam PF02311 AraC-like ligand binding domain 19 119 3.2E-8 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 Gene3D G3DSA:1.10.10.60 166 210 1.9E-7 T 28-03-2018 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 Gene3D G3DSA:1.10.10.60 211 259 3.4E-8 T 28-03-2018 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 Pfam PF12833 Helix-turn-helix domain 177 254 2.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS14440 66311f59f38e555e04d972ec09b7fde0 262 SMART SM00342 171 253 1.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS01910 d4a0be99e7f3b60ca9527805ce1ed756 433 Pfam PF13520 Amino acid permease 14 403 3.2E-47 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS01910 d4a0be99e7f3b60ca9527805ce1ed756 433 PIRSF PIRSF006060 1 431 3.7E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS20875 e526310b3645bec8faf286a6eeab6819 236 Gene3D G3DSA:3.30.70.1290 2 131 4.9E-28 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS20875 e526310b3645bec8faf286a6eeab6819 236 SUPERFAMILY SSF143422 3 127 5.49E-29 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS20875 e526310b3645bec8faf286a6eeab6819 236 SMART SM01321 9 124 3.8E-36 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS20875 e526310b3645bec8faf286a6eeab6819 236 Pfam PF01797 Transposase IS200 like 13 124 3.8E-13 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SmaCSM2_RS15585 d60778413722d381d4bfcfa967cb1f23 216 Gene3D G3DSA:3.30.1150.10 59 216 3.2E-18 T 28-03-2018 SmaCSM2_RS15585 d60778413722d381d4bfcfa967cb1f23 216 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 137 214 2.5E-17 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS15585 d60778413722d381d4bfcfa967cb1f23 216 SUPERFAMILY SSF74653 130 212 9.29E-20 T 28-03-2018 SmaCSM2_RS15585 d60778413722d381d4bfcfa967cb1f23 216 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 135 214 2.6E-19 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS05770 5e0e3b470c6eb8b9a188bfce310c58bd 269 SUPERFAMILY SSF52540 4 267 2.02E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05770 5e0e3b470c6eb8b9a188bfce310c58bd 269 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 7.3E-22 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SmaCSM2_RS05770 5e0e3b470c6eb8b9a188bfce310c58bd 269 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 266 3.3E-110 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 SmaCSM2_RS05770 5e0e3b470c6eb8b9a188bfce310c58bd 269 Gene3D G3DSA:3.40.50.300 1 259 2.2E-52 T 28-03-2018 SmaCSM2_RS05770 5e0e3b470c6eb8b9a188bfce310c58bd 269 PIRSF PIRSF003092 1 269 2.3E-90 T 28-03-2018 IPR025501 ATP binding protein MinD SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 363 377 2.0E-28 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 61 73 2.0E-28 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 379 398 2.0E-28 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 160 188 2.0E-28 T 28-03-2018 IPR003004 GspF/PilC family SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 Pfam PF00482 Type II secretion system (T2SS), protein F 66 188 3.1E-31 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 Pfam PF00482 Type II secretion system (T2SS), protein F 268 390 1.0E-26 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS12155 2b2924571afa646a9172a003f4d72283 399 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 398 4.2E-156 T 28-03-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 SUPERFAMILY SSF51735 4 251 2.48E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 Gene3D G3DSA:3.40.50.10090 2 47 2.2E-10 T 28-03-2018 SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 2.1E-64 T 28-03-2018 SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 6.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS12925 b0a9859c1b6faf243a3d80e6998eed30 252 Gene3D G3DSA:3.40.50.720 48 252 4.0E-61 T 28-03-2018 SmaCSM2_RS11895 14dc01406691a6e91aa55f0656582fa6 177 Pfam PF10986 Protein of unknown function (DUF2796) 25 170 7.5E-26 T 28-03-2018 IPR021253 Protein of unknown function DUF2796 SmaCSM2_RS10975 2369b2bc5ba831fa0d0b59a21c108300 124 SMART SM00342 39 121 1.3E-7 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10975 2369b2bc5ba831fa0d0b59a21c108300 124 Gene3D G3DSA:1.10.10.60 77 123 8.8E-9 T 28-03-2018 SmaCSM2_RS10975 2369b2bc5ba831fa0d0b59a21c108300 124 SUPERFAMILY SSF46689 78 122 2.42E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS10975 2369b2bc5ba831fa0d0b59a21c108300 124 Pfam PF12833 Helix-turn-helix domain 45 120 1.5E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS10975 2369b2bc5ba831fa0d0b59a21c108300 124 Gene3D G3DSA:1.10.10.60 16 76 0.0023 T 28-03-2018 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 SUPERFAMILY SSF48498 104 185 1.33E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 SUPERFAMILY SSF46689 23 91 2.0E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 Gene3D G3DSA:1.10.357.10 79 215 5.2E-14 T 28-03-2018 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 76 5.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18070 73486f83df68f130c2c16a13a135d828 220 Gene3D G3DSA:1.10.10.60 2 78 2.2E-18 T 28-03-2018 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 Gene3D G3DSA:3.10.310.10 133 270 2.9E-45 T 28-03-2018 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 Pfam PF01678 Diaminopimelate epimerase 11 130 3.0E-24 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 Pfam PF01678 Diaminopimelate epimerase 161 275 7.2E-23 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 SUPERFAMILY SSF54506 147 281 1.86E-44 T 28-03-2018 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 Gene3D G3DSA:3.10.310.10 1 132 5.0E-44 T 28-03-2018 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 SUPERFAMILY SSF54506 9 138 9.03E-41 T 28-03-2018 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 72 86 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 10 281 2.9E-74 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SmaCSM2_RS18485 9bc0f0ce9b878a5298d9b2ae738d35d3 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 9 283 35.744 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SmaCSM2_RS17465 35ef47e5da0d7aafca6708bb1b56f174 443 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 3 440 53.075 T 28-03-2018 IPR022846 Xaa-Pro dipeptidase GO:0016795 SmaCSM2_RS17465 35ef47e5da0d7aafca6708bb1b56f174 443 Gene3D G3DSA:3.90.230.10 158 440 2.9E-50 T 28-03-2018 SmaCSM2_RS17465 35ef47e5da0d7aafca6708bb1b56f174 443 SUPERFAMILY SSF55920 161 435 4.06E-53 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS17465 35ef47e5da0d7aafca6708bb1b56f174 443 Pfam PF00557 Metallopeptidase family M24 167 427 1.4E-41 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS17465 35ef47e5da0d7aafca6708bb1b56f174 443 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 332 344 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 96 734 1.2E-95 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 Gene3D G3DSA:2.40.170.20 203 734 2.1E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 SUPERFAMILY SSF56935 52 734 2.88E-123 T 28-03-2018 SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 Pfam PF07715 TonB-dependent Receptor Plug Domain 93 194 6.8E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 717 734 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 Pfam PF00593 TonB dependent receptor 302 733 9.5E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08240 e41eb873dc2cc1a17d55cec539dc5a49 734 Gene3D G3DSA:2.170.130.10 51 202 2.2E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05090 f21c6d646cc5ff1ca36fb02b5b9b36de 150 SUPERFAMILY SSF55804 15 141 8.76E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SmaCSM2_RS05090 f21c6d646cc5ff1ca36fb02b5b9b36de 150 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain SmaCSM2_RS05090 f21c6d646cc5ff1ca36fb02b5b9b36de 150 Gene3D G3DSA:3.40.930.10 1 144 3.7E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SmaCSM2_RS05090 f21c6d646cc5ff1ca36fb02b5b9b36de 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 16 141 2.6E-28 T 28-03-2018 IPR002178 PTS EIIA type-2 domain SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 Gene3D G3DSA:3.40.50.10860 1 111 2.6E-36 T 28-03-2018 SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 SUPERFAMILY SSF53223 2 101 5.64E-29 T 28-03-2018 SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 2.3E-24 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 SUPERFAMILY SSF51735 102 271 5.1E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 Gene3D G3DSA:3.40.50.720 112 277 3.9E-36 T 28-03-2018 SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 5 271 2.5E-71 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 193 3.6E-11 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SmaCSM2_RS20800 376ad6c65a243d8dc6528caf7961da0e 281 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 30.886 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SmaCSM2_RS18900 cc6dee166db751e43d6dfee7fe80272e 150 Gene3D G3DSA:1.20.1260.10 1 147 1.9E-15 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS18900 cc6dee166db751e43d6dfee7fe80272e 150 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 7 144 1.0E-46 T 28-03-2018 IPR011971 Conserved hypothetical protein CHP02284 SmaCSM2_RS18900 cc6dee166db751e43d6dfee7fe80272e 150 Pfam PF09537 Domain of unknown function (DUF2383) 7 115 1.8E-30 T 28-03-2018 IPR019052 Domain of unknown function DUF2383 SmaCSM2_RS05240 d8fdedc16fbf1588adb788ab83da6927 323 PIRSF PIRSF006268 6 315 2.3E-79 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SmaCSM2_RS05240 d8fdedc16fbf1588adb788ab83da6927 323 SUPERFAMILY SSF143631 10 317 1.44E-90 T 28-03-2018 IPR003374 ApbE-like domain SmaCSM2_RS05240 d8fdedc16fbf1588adb788ab83da6927 323 Gene3D G3DSA:3.10.520.10 14 301 5.7E-49 T 28-03-2018 SmaCSM2_RS05240 d8fdedc16fbf1588adb788ab83da6927 323 Pfam PF02424 ApbE family 16 296 3.1E-80 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 Gene3D G3DSA:1.10.10.60 236 275 4.0E-9 T 28-03-2018 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 SUPERFAMILY SSF46689 272 322 1.15E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 Gene3D G3DSA:1.10.10.60 276 324 1.9E-12 T 28-03-2018 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 Gene3D G3DSA:3.40.50.880 6 235 3.1E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 272 314 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 Pfam PF12833 Helix-turn-helix domain 241 319 8.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 SUPERFAMILY SSF52317 13 201 2.46E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 Pfam PF01965 DJ-1/PfpI family 73 180 9.8E-17 T 28-03-2018 IPR002818 DJ-1/PfpI SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 SMART SM00342 235 318 9.5E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09240 d461c72535c4149efae575920859803b 333 SUPERFAMILY SSF46689 219 269 2.33E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13770 c39f6209855997594a56ea86734872ce 260 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 80 243 1.1E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS13770 c39f6209855997594a56ea86734872ce 260 Gene3D G3DSA:3.40.50.1110 47 257 3.6E-48 T 28-03-2018 SmaCSM2_RS13770 c39f6209855997594a56ea86734872ce 260 SUPERFAMILY SSF52266 61 251 3.21E-52 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS14390 158e793e15d20c59bd8123cb25f66993 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 286 2.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS14390 158e793e15d20c59bd8123cb25f66993 293 SUPERFAMILY SSF161098 54 280 7.06E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS14390 158e793e15d20c59bd8123cb25f66993 293 Gene3D G3DSA:1.10.3720.10 7 293 5.0E-52 T 28-03-2018 SmaCSM2_RS19125 caaf7bba955af7abb16270e9f70e2c18 193 Pfam PF11304 Protein of unknown function (DUF3106) 49 104 2.7E-7 T 28-03-2018 IPR021455 Protein of unknown function DUF3106 SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 Pfam PF09906 Uncharacterized protein conserved in bacteria (DUF2135) 908 955 7.0E-18 T 28-03-2018 IPR019220 Domain of unknown function DUF2135 SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 SMART SM00609 31 159 0.0095 T 28-03-2018 IPR013694 VIT domain SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 Pfam PF08487 Vault protein inter-alpha-trypsin domain 48 155 1.9E-19 T 28-03-2018 IPR013694 VIT domain SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 SUPERFAMILY SSF53300 259 407 2.89E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 Gene3D G3DSA:1.25.40.10 679 823 5.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 SUPERFAMILY SSF48452 696 798 6.33E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09855 bb5137bd985d6bbff1ab31d6a35beb8c 970 Gene3D G3DSA:2.60.120.380 845 944 0.0015 T 28-03-2018 SmaCSM2_RS04485 354e0c22440090fe3e9b281c19b16a06 150 Pfam PF00075 RNase H 4 140 8.7E-47 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 SmaCSM2_RS04485 354e0c22440090fe3e9b281c19b16a06 150 Gene3D G3DSA:3.30.420.10 2 144 2.0E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS04485 354e0c22440090fe3e9b281c19b16a06 150 SUPERFAMILY SSF53098 3 140 5.69E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS04485 354e0c22440090fe3e9b281c19b16a06 150 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 36.66 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 SmaCSM2_RS20460 8479bea1aed468431267388ea53f3da5 800 Gene3D G3DSA:2.170.130.10 34 181 3.2E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20460 8479bea1aed468431267388ea53f3da5 800 Gene3D G3DSA:2.40.170.20 182 800 9.2E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20460 8479bea1aed468431267388ea53f3da5 800 SUPERFAMILY SSF56935 44 793 8.96E-104 T 28-03-2018 SmaCSM2_RS20460 8479bea1aed468431267388ea53f3da5 800 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 174 7.6E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20460 8479bea1aed468431267388ea53f3da5 800 Pfam PF00593 TonB dependent receptor 298 783 7.2E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 242 9.8E-57 T 28-03-2018 SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 SUPERFAMILY SSF51735 4 242 6.42E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 Gene3D G3DSA:3.40.50.720 50 243 7.5E-59 T 28-03-2018 SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 191 2.0E-5 T 28-03-2018 SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 7 243 5.5E-122 T 28-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS21065 bf659e17d49d5c10a158f146860bf3ed 243 Gene3D G3DSA:3.40.50.10090 2 49 1.3E-10 T 28-03-2018 SmaCSM2_RS16860 0ec60fc1f37c8b29383591f14c73fca0 454 SUPERFAMILY SSF53756 2 453 1.76E-141 T 28-03-2018 SmaCSM2_RS16860 0ec60fc1f37c8b29383591f14c73fca0 454 Pfam PF00982 Glycosyltransferase family 20 16 453 1.8E-124 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 SmaCSM2_RS16860 0ec60fc1f37c8b29383591f14c73fca0 454 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 453 5.6E-180 T 28-03-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 SmaCSM2_RS16860 0ec60fc1f37c8b29383591f14c73fca0 454 Gene3D G3DSA:3.40.50.2000 240 438 2.5E-39 T 28-03-2018 SmaCSM2_RS16860 0ec60fc1f37c8b29383591f14c73fca0 454 Gene3D G3DSA:3.40.50.2000 1 239 3.4E-61 T 28-03-2018 SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 674 785 1.2E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 Gene3D G3DSA:3.30.565.10 523 778 4.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 20 215 4.4E-16 T 28-03-2018 SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 SUPERFAMILY SSF55874 116 203 2.36E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 SMART SM00387 671 791 1.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 SUPERFAMILY SSF55874 629 771 7.33E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 Gene3D G3DSA:3.30.565.10 1 290 3.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 728 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 PRINTS PR00344 Bacterial sensor protein C-terminal signature 747 765 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11050 0415e011616b0c9d94d4f73d88f3788b 793 PRINTS PR00344 Bacterial sensor protein C-terminal signature 732 742 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 SUPERFAMILY SSF51430 2 259 9.17E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PIRSF PIRSF000097 1 264 2.1E-66 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PRINTS PR00069 Aldo-keto reductase signature 149 178 1.9E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PRINTS PR00069 Aldo-keto reductase signature 186 210 1.9E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PRINTS PR00069 Aldo-keto reductase signature 25 49 1.9E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PRINTS PR00069 Aldo-keto reductase signature 81 99 1.9E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 PRINTS PR00069 Aldo-keto reductase signature 114 131 1.9E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 Gene3D G3DSA:3.20.20.100 1 261 8.1E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SmaCSM2_RS11910 ffca29c5cd658b6bbc53aa4c959eed61 267 Pfam PF00248 Aldo/keto reductase family 8 251 1.6E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS09690 28790dd73f36ceb35715cbe41e2b7c07 491 PIRSF PIRSF006060 22 490 3.4E-93 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS09690 28790dd73f36ceb35715cbe41e2b7c07 491 Pfam PF13520 Amino acid permease 41 461 3.5E-58 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS20445 9fcab9881eeabd45b65ec1c8491adc09 199 Gene3D G3DSA:3.40.30.10 39 174 5.3E-5 T 28-03-2018 SmaCSM2_RS20445 9fcab9881eeabd45b65ec1c8491adc09 199 SUPERFAMILY SSF52833 59 196 3.64E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 SUPERFAMILY SSF51735 2 231 2.58E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.3E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.3E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.3E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 Gene3D G3DSA:3.40.50.720 2 242 8.1E-60 T 28-03-2018 SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 5.1E-5 T 28-03-2018 SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS20195 ccde0a98123eb9c27fc980acb67ee9a5 247 Pfam PF00106 short chain dehydrogenase 8 195 2.0E-55 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 SMART SM00347 32 133 4.1E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 3.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 3.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 3.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 3.9E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 Gene3D G3DSA:1.10.10.10 4 151 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 Pfam PF12802 MarR family 38 97 1.6E-8 T 28-03-2018 SmaCSM2_RS21585 78be1b7c97676961a8dab52f5728b355 151 SUPERFAMILY SSF46785 1 148 9.69E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 SUPERFAMILY SSF53335 224 317 2.04E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 SUPERFAMILY SSF53335 19 124 2.04E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 19 318 38.032 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 Gene3D G3DSA:1.10.150.170 123 226 1.2E-38 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 PIRSF PIRSF004486 13 319 1.8E-99 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 17 317 5.5E-102 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 Pfam PF01795 MraW methylase family 18 318 1.6E-102 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03225 9fe2c58e5901210109e0629a4ee5a9c9 322 SUPERFAMILY SSF81799 125 224 9.16E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS16395 f768c5c281a4362cc603c6849a02b2da 442 Gene3D G3DSA:1.20.1250.20 240 442 0.0039 T 28-03-2018 SmaCSM2_RS16395 f768c5c281a4362cc603c6849a02b2da 442 SUPERFAMILY SSF103473 23 440 1.13E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS16395 f768c5c281a4362cc603c6849a02b2da 442 Pfam PF07690 Major Facilitator Superfamily 74 346 5.2E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS16395 f768c5c281a4362cc603c6849a02b2da 442 Gene3D G3DSA:1.20.1250.20 13 232 3.7E-19 T 28-03-2018 SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 Gene3D G3DSA:1.10.10.10 177 255 4.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 Pfam PF13545 Crp-like helix-turn-helix domain 175 249 3.2E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 Pfam PF00027 Cyclic nucleotide-binding domain 62 137 3.7E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 Gene3D G3DSA:2.60.120.10 58 176 8.1E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 SUPERFAMILY SSF51206 62 161 2.36E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 SUPERFAMILY SSF46785 174 250 5.77E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 SMART SM00100 43 161 6.6E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 200 216 1.2E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 216 231 1.2E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12260 31106129e2ffac816af91b13e80650a4 258 SMART SM00419 194 242 1.9E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS04370 7c3e7e6ec05d899285173414c231be66 206 SUPERFAMILY SSF50475 3 195 6.87E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS04370 7c3e7e6ec05d899285173414c231be66 206 Gene3D G3DSA:2.30.110.10 11 193 1.8E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS04370 7c3e7e6ec05d899285173414c231be66 206 SMART SM00903 25 176 1.3E-9 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS04370 7c3e7e6ec05d899285173414c231be66 206 Pfam PF01613 Flavin reductase like domain 27 166 4.4E-17 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 SMART SM00862 145 216 1.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 Gene3D G3DSA:1.10.10.10 132 219 7.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 8.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 SMART SM00448 1 112 4.4E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 Gene3D G3DSA:3.40.50.2300 1 131 1.7E-30 T 28-03-2018 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 Pfam PF00072 Response regulator receiver domain 3 112 2.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19915 0dab062d0c6ff5740fbee4e97ba1ed05 219 SUPERFAMILY SSF52172 1 179 1.17E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 PIRSF PIRSF001455 17 369 7.2E-102 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 SUPERFAMILY SSF56796 13 367 2.49E-105 T 28-03-2018 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 Gene3D G3DSA:1.20.1090.10 179 370 3.1E-68 T 28-03-2018 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 Gene3D G3DSA:3.40.50.1970 8 178 7.9E-46 T 28-03-2018 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 Pfam PF01761 3-dehydroquinate synthase 74 336 1.8E-101 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 18 365 3.3E-106 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SmaCSM2_RS16245 4f3de75ee7b43d97fe4b9e508827207c 370 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 5 369 39.519 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SmaCSM2_RS08605 706f3069dafd7cc09d74d78b9d52b7f0 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 384 2.2E-83 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS08605 706f3069dafd7cc09d74d78b9d52b7f0 407 Gene3D G3DSA:2.40.50.100 71 143 1.2E-19 T 28-03-2018 SmaCSM2_RS08605 706f3069dafd7cc09d74d78b9d52b7f0 407 SUPERFAMILY SSF111369 60 306 4.84E-74 T 28-03-2018 SmaCSM2_RS08605 706f3069dafd7cc09d74d78b9d52b7f0 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 302 1.1E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS08605 706f3069dafd7cc09d74d78b9d52b7f0 407 Gene3D G3DSA:2.40.50.100 171 358 1.5E-5 T 28-03-2018 SmaCSM2_RS15735 8378a1df2e5f4b516e3b0a0aed45f43a 205 Pfam PF06197 Protein of unknown function (DUF998) 13 193 2.1E-13 T 28-03-2018 IPR009339 Protein of unknown function DUF998 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 SUPERFAMILY SSF63380 93 195 6.72E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 Gene3D G3DSA:2.40.30.20 1 89 2.8E-25 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 Gene3D G3DSA:2.40.30.20 94 191 8.5E-34 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 Pfam PF00677 Lumazine binding domain 3 87 1.3E-19 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 Pfam PF00677 Lumazine binding domain 100 184 2.2E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 SUPERFAMILY SSF63380 1 93 1.53E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 PIRSF PIRSF000498 1 200 2.8E-72 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS03140 cbecf6a5bdb0cbbf84cca0f29564fad3 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 3.7E-60 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 8 164 15.994 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 55 63 5.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 103 118 5.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 139 155 5.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 TIGRFAM TIGR00077 lspA: signal peptidase II 12 166 3.5E-40 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS05925 6c2a4d185800a1bc2365a7ce1fc3aac7 174 Pfam PF01252 Signal peptidase (SPase) II 18 158 2.1E-35 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 SUPERFAMILY SSF54768 21 89 9.1E-22 T 28-03-2018 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 ProSitePatterns PS00585 Ribosomal protein S5 signature. 41 73 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 Gene3D G3DSA:3.30.160.20 24 85 5.0E-24 T 28-03-2018 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 Pfam PF00333 Ribosomal protein S5, N-terminal domain 26 87 1.4E-26 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 Gene3D G3DSA:3.30.230.10 89 179 4.6E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 SUPERFAMILY SSF54211 92 172 3.29E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 24 176 5.9E-64 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 Pfam PF03719 Ribosomal protein S5, C-terminal domain 102 170 6.6E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS04075 8fcdc8708893670d20149012b4508679 180 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 176 34.049 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 Pfam PF00455 DeoR C terminal sensor domain 79 233 1.5E-53 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 Gene3D G3DSA:1.10.10.10 1 70 9.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 SMART SM01134 74 235 2.4E-72 T 28-03-2018 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 SUPERFAMILY SSF100950 76 237 5.44E-34 T 28-03-2018 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 SMART SM00420 7 59 6.4E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 3.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 3.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 Pfam PF08220 DeoR-like helix-turn-helix domain 7 60 3.4E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 Gene3D G3DSA:3.40.50.1360 71 254 7.7E-42 T 28-03-2018 SmaCSM2_RS20600 d70ef2d3ffbf91445b8f156e8d35979a 258 SUPERFAMILY SSF46785 5 67 1.29E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 Gene3D G3DSA:3.40.1190.20 47 318 9.3E-35 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 Pfam PF00294 pfkB family carbohydrate kinase 23 297 1.7E-47 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 Gene3D G3DSA:2.20.150.10 12 46 9.0E-15 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 6 314 2.2E-88 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 SUPERFAMILY SSF53613 6 293 2.81E-58 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 PIRSF PIRSF000535 2 317 3.3E-95 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SmaCSM2_RS11270 34572baeac9ae2893efb9c0dc662e1d7 318 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 6 314 7.3E-90 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 43 58 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 Pfam PF02542 YgbB family 9 162 3.9E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 SUPERFAMILY SSF69765 9 163 1.02E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 9 164 36.167 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 10 163 9.9E-69 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS08045 290f3eb3d1277dd223bebb86a3960968 165 Gene3D G3DSA:3.30.1330.50 2 165 2.9E-71 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 Gene3D G3DSA:3.40.50.2300 1 119 1.2E-26 T 28-03-2018 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 Pfam PF00072 Response regulator receiver domain 6 118 2.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 SMART SM00421 146 203 2.0E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 SUPERFAMILY SSF52172 4 130 5.69E-27 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 Gene3D G3DSA:1.10.10.10 120 207 5.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 4.0E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 SUPERFAMILY SSF46894 131 204 1.09E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS17885 46171cf44d972c190a73182a9db1aa99 216 SMART SM00448 4 118 4.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03470 4244ebb8a09f9f90944bba9abeeb7109 215 Gene3D G3DSA:3.40.50.300 1 214 2.7E-60 T 28-03-2018 SmaCSM2_RS03470 4244ebb8a09f9f90944bba9abeeb7109 215 Pfam PF00005 ABC transporter 11 156 1.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS03470 4244ebb8a09f9f90944bba9abeeb7109 215 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS03470 4244ebb8a09f9f90944bba9abeeb7109 215 SMART SM00382 20 202 9.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS03470 4244ebb8a09f9f90944bba9abeeb7109 215 SUPERFAMILY SSF52540 5 209 3.64E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02305 28906bdb6d28332cca8d30f64191557d 419 SMART SM00387 316 412 4.7E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02305 28906bdb6d28332cca8d30f64191557d 419 Gene3D G3DSA:3.30.565.10 281 418 1.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS02305 28906bdb6d28332cca8d30f64191557d 419 Pfam PF06580 Histidine kinase 222 301 1.5E-19 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SmaCSM2_RS02305 28906bdb6d28332cca8d30f64191557d 419 SUPERFAMILY SSF55874 283 409 1.57E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 26 57 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Hamap MF_00105 Transcription elongation factor GreA [greA]. 11 164 28.983 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Hamap MF_00930 Transcription elongation factor GreB [greB]. 10 166 50.326 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Gene3D G3DSA:3.10.50.30 86 168 2.0E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 SUPERFAMILY SSF54534 89 165 7.85E-22 T 28-03-2018 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 SUPERFAMILY SSF46557 13 87 8.89E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Pfam PF03449 Transcription elongation factor, N-terminal 14 83 2.6E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 129 145 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 PIRSF PIRSF006092 8 167 3.6E-51 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 92 165 2.4E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 Gene3D G3DSA:1.10.287.180 12 85 1.8E-27 T 28-03-2018 SmaCSM2_RS15345 513bd6df5141565b7b12802fa83ce1e4 168 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 12 166 4.8E-62 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 Pfam PF01343 Peptidase family S49 150 265 7.3E-21 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 Pfam PF01343 Peptidase family S49 407 558 2.8E-47 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 SUPERFAMILY SSF52096 46 189 3.48E-16 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 SUPERFAMILY SSF52096 221 296 3.48E-16 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 Gene3D G3DSA:3.40.1750.10 198 307 6.1E-16 T 28-03-2018 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 Gene3D G3DSA:3.90.226.10 96 192 0.0018 T 28-03-2018 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 SUPERFAMILY SSF52096 484 544 1.33E-39 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 SUPERFAMILY SSF52096 338 455 1.33E-39 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 Gene3D G3DSA:3.90.226.10 334 626 4.9E-46 T 28-03-2018 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 368 554 6.8E-50 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 24 584 7.9E-158 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 SmaCSM2_RS19115 45c135f02e4291e7f4e51905ea02bb33 640 PIRSF PIRSF001217 16 636 3.1E-200 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 SmaCSM2_RS20420 b0ce3a96d377153312ff93441bacd510 211 SUPERFAMILY SSF81452 16 209 1.14E-59 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20420 b0ce3a96d377153312ff93441bacd510 211 Pfam PF00510 Cytochrome c oxidase subunit III 27 209 9.7E-15 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20420 b0ce3a96d377153312ff93441bacd510 211 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 32 210 4.1E-82 T 28-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 SmaCSM2_RS20420 b0ce3a96d377153312ff93441bacd510 211 Gene3D G3DSA:1.20.120.80 26 211 1.1E-53 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 272 296 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 297 315 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 220 246 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 247 271 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 190 204 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 63 79 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 PRINTS PR01050 Pyruvate kinase family signature 316 332 5.0E-57 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 SUPERFAMILY SSF50800 74 171 2.27E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 Gene3D G3DSA:3.40.1380.20 325 477 5.8E-45 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 SUPERFAMILY SSF51621 171 342 9.07E-89 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 SUPERFAMILY SSF51621 4 79 9.07E-89 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 Gene3D G3DSA:3.20.20.60 6 170 8.4E-34 T 28-03-2018 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 Gene3D G3DSA:3.20.20.60 171 324 6.3E-56 T 28-03-2018 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 476 1.2E-156 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 SUPERFAMILY SSF52935 326 476 2.22E-34 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 Pfam PF00224 Pyruvate kinase, barrel domain 6 345 1.5E-120 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS17150 7745978e9b23fd26a7af583d1e672764 488 Pfam PF02887 Pyruvate kinase, alpha/beta domain 360 473 1.4E-26 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF56042 421 651 4.19E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF109736 158 212 1.44E-18 T 28-03-2018 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1042 1293 5.6E-100 T 28-03-2018 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1294 20.337 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1292 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF52317 1039 1293 4.58E-91 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.90.650.10 820 997 1.4E-26 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF55326 213 415 7.67E-51 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.90.650.10 403 601 4.6E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.40.50.880 1041 1293 1.2E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF82697 1 148 2.67E-31 T 28-03-2018 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF56042 819 1035 1.64E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SMART SM01211 1042 1293 2.2E-140 T 28-03-2018 SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Pfam PF02769 AIR synthase related protein, C-terminal domain 825 962 1.4E-9 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Pfam PF02769 AIR synthase related protein, C-terminal domain 421 578 2.1E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 SUPERFAMILY SSF55326 616 812 4.97E-68 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.30.1330.10 210 402 3.1E-43 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.30.1330.10 175 209 0.015 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS02945 1c3bd0e7f543eaa0a89a8f6ad66f62e7 1294 Gene3D G3DSA:3.30.1330.10 640 809 4.8E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 Gene3D G3DSA:3.40.50.720 1 177 4.5E-27 T 28-03-2018 SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 295 5.2E-110 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 SUPERFAMILY SSF51735 1 295 7.56E-100 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 Gene3D G3DSA:3.90.25.10 204 282 1.7E-24 T 28-03-2018 SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 Gene3D G3DSA:3.90.25.10 178 203 2.6E-5 T 28-03-2018 SmaCSM2_RS02785 040a88df6831361a6e9c8ae7d200ac3c 296 Pfam PF04321 RmlD substrate binding domain 1 295 1.8E-109 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 SmaCSM2_RS15385 9da93dd9c539e4e247e4a4b2dd4f329b 771 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 552 625 5.2E-25 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal SmaCSM2_RS11115 a9d1c04cb9e7df893e473f9e967a2c57 362 Gene3D G3DSA:3.40.50.450 1 157 4.7E-4 T 28-03-2018 SmaCSM2_RS11115 a9d1c04cb9e7df893e473f9e967a2c57 362 Pfam PF13271 Domain of unknown function (DUF4062) 9 90 4.8E-28 T 28-03-2018 IPR025139 Domain of unknown function DUF4062 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 253 270 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 SUPERFAMILY SSF52279 372 608 3.79E-49 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Pfam PF14310 Fibronectin type III-like domain 642 711 1.2E-20 T 28-03-2018 IPR026891 Fibronectin type III-like domain SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Gene3D G3DSA:3.40.50.1700 357 605 2.6E-69 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 SMART SM01217 642 711 1.9E-30 T 28-03-2018 IPR026891 Fibronectin type III-like domain SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Gene3D G3DSA:2.60.40.10 606 721 2.6E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Gene3D G3DSA:3.20.20.300 1 356 7.1E-101 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 372 605 1.7E-49 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 14 330 6.2E-69 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 SUPERFAMILY SSF51445 3 371 3.26E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 PRINTS PR00133 Glycosyl hydrolase family 3 signature 100 119 1.6E-18 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 PRINTS PR00133 Glycosyl hydrolase family 3 signature 183 199 1.6E-18 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 PRINTS PR00133 Glycosyl hydrolase family 3 signature 81 97 1.6E-18 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 PRINTS PR00133 Glycosyl hydrolase family 3 signature 253 271 1.6E-18 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS01885 d99ad5b95e36484a2eefee60c64e15fd 724 PRINTS PR00133 Glycosyl hydrolase family 3 signature 146 162 1.6E-18 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SmaCSM2_RS21140 6001751d6343337dabf041aa28a4d305 265 SMART SM00563 88 196 3.5E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS21140 6001751d6343337dabf041aa28a4d305 265 Pfam PF01553 Acyltransferase 76 193 6.3E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS21140 6001751d6343337dabf041aa28a4d305 265 SUPERFAMILY SSF69593 47 236 2.62E-23 T 28-03-2018 SmaCSM2_RS21140 6001751d6343337dabf041aa28a4d305 265 Gene3D G3DSA:3.40.1130.10 40 256 3.9E-25 T 28-03-2018 SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 SUPERFAMILY SSF53383 83 456 8.34E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 SUPERFAMILY SSF46785 3 74 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 Gene3D G3DSA:3.90.1150.10 351 456 1.9E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 Gene3D G3DSA:1.10.10.10 2 72 2.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 Pfam PF00155 Aminotransferase class I and II 135 453 5.3E-37 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 SMART SM00345 11 70 5.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 Gene3D G3DSA:3.40.640.10 141 350 1.1E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS04895 9cc22d570b345a28aa0c255f4200d98d 459 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 8.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 Gene3D G3DSA:3.30.360.10 137 208 2.9E-26 T 28-03-2018 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 SUPERFAMILY SSF55347 123 210 1.98E-22 T 28-03-2018 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 124 238 6.5E-34 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 145 162 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 7 121 2.5E-22 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 6 166 5.7E-39 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 PIRSF PIRSF000161 4 239 1.1E-67 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 239 28.584 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 Gene3D G3DSA:3.40.50.720 3 136 2.7E-18 T 28-03-2018 SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 SUPERFAMILY SSF51735 210 238 1.88E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09820 2221a0a48827a4e2f76a8ae0ad8beecb 239 SUPERFAMILY SSF51735 5 122 1.88E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS07550 fc7d3f5d9a363072d923e53f6a8a7e4a 315 Pfam PF06834 TraU protein 36 303 6.8E-74 T 28-03-2018 IPR009649 TraU SmaCSM2_RS07550 fc7d3f5d9a363072d923e53f6a8a7e4a 315 TIGRFAM TIGR03756 conj_TIGR03756: integrating conjugative element protein, PFL_4710 family 29 313 1.5E-131 T 28-03-2018 IPR026331 Integrating conjugative element protein PFL_4710 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 Gene3D G3DSA:1.10.1660.10 1 121 4.9E-18 T 28-03-2018 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 Pfam PF13411 MerR HTH family regulatory protein 4 72 8.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 SUPERFAMILY SSF46955 4 109 1.65E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 TIGRFAM TIGR02054 MerD: mercuric resistence transcriptional repressor protein MerD 1 119 2.1E-62 T 28-03-2018 IPR011797 Mercuric resistence transcriptional repressor protein MerD GO:0003677|GO:0045892|GO:0046689 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 SMART SM00422 4 73 5.0E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 8.0E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 8.0E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10735 5d6198366ac52e04b51c59c736db2941 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 8.0E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS21640 6d95f4ca6a4fa64baa6ca5295eb8edb6 174 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 7 150 1.3E-47 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 SmaCSM2_RS21640 6d95f4ca6a4fa64baa6ca5295eb8edb6 174 Pfam PF02470 MlaD protein 40 119 1.6E-21 T 28-03-2018 IPR003399 Mce/MlaD SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Gene3D G3DSA:3.40.50.300 5 235 2.6E-54 T 28-03-2018 SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Pfam PF00270 DEAD/DEAH box helicase 33 206 5.1E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 SMART SM00490 271 352 4.0E-31 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 SUPERFAMILY SSF52540 84 363 4.65E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 SMART SM00487 28 235 4.2E-56 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 164 172 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Pfam PF12300 ATP-dependent RNA helicase RhlB 377 553 2.5E-68 T 28-03-2018 IPR022077 ATP-dependent RNA helicase RhlB GO:0016817 SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 390 50.447 T 28-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Pfam PF00271 Helicase conserved C-terminal domain 244 352 7.5E-28 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS19445 1331189895402915d8ecacfc6dc00fd1 573 Gene3D G3DSA:3.40.50.300 236 536 1.2E-42 T 28-03-2018 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 Gene3D G3DSA:3.40.50.1820 417 698 1.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 28 414 3.1E-34 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 609 624 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 470 488 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 525 544 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 555 575 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 497 521 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 628 650 7.7E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 SUPERFAMILY SSF53474 440 695 2.49E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 SUPERFAMILY SSF50993 26 433 1.91E-58 T 28-03-2018 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 Gene3D G3DSA:2.130.10.120 76 416 4.6E-27 T 28-03-2018 SmaCSM2_RS18510 497f7c8f8b51f0faebf654553ecc33b3 698 Pfam PF00326 Prolyl oligopeptidase family 494 696 1.6E-49 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS04850 ac301a52af633d5d136dec24200c7df7 126 Pfam PF14552 Tautomerase enzyme 37 118 1.1E-34 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SmaCSM2_RS04850 ac301a52af633d5d136dec24200c7df7 126 SUPERFAMILY SSF55331 2 125 6.01E-41 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily SmaCSM2_RS04850 ac301a52af633d5d136dec24200c7df7 126 Gene3D G3DSA:3.30.429.10 1 126 2.6E-31 T 28-03-2018 SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 SUPERFAMILY SSF47413 8 72 3.66E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 SMART SM00530 13 67 6.4E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 PIRSF PIRSF019251 5 454 1.8E-153 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 312 452 5.0E-60 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 Pfam PF06114 IrrE N-terminal-like domain 188 311 9.2E-19 T 28-03-2018 IPR010359 IrrE N-terminal-like domain SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 Gene3D G3DSA:1.10.260.40 2 87 9.3E-16 T 28-03-2018 SmaCSM2_RS01175 b975c7a90eee5bf9f03042dd2f93fb0b 455 Pfam PF13560 Helix-turn-helix domain 9 62 1.0E-11 T 28-03-2018 SmaCSM2_RS09595 46cd4448ec5ed3e63d10297f3bca3aae 245 Gene3D G3DSA:3.20.20.380 4 244 4.2E-83 T 28-03-2018 SmaCSM2_RS09595 46cd4448ec5ed3e63d10297f3bca3aae 245 Pfam PF03932 CutC family 6 205 6.8E-74 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SmaCSM2_RS09595 46cd4448ec5ed3e63d10297f3bca3aae 245 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 5 242 36.438 T 28-03-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 SmaCSM2_RS09595 46cd4448ec5ed3e63d10297f3bca3aae 245 SUPERFAMILY SSF110395 6 242 3.01E-70 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SmaCSM2_RS00935 0cdd04762b0458376785627be411a122 195 Gene3D G3DSA:3.40.50.150 18 176 2.3E-34 T 28-03-2018 SmaCSM2_RS00935 0cdd04762b0458376785627be411a122 195 SUPERFAMILY SSF53335 20 193 5.52E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS00935 0cdd04762b0458376785627be411a122 195 Pfam PF01596 O-methyltransferase 22 160 1.3E-25 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SmaCSM2_RS02850 2dc1b2be17c78e7be6db5512029cdccc 127 SUPERFAMILY SSF81273 82 125 1.96E-12 T 28-03-2018 SmaCSM2_RS02850 2dc1b2be17c78e7be6db5512029cdccc 127 Pfam PF00816 H-NS histone family 12 116 1.3E-23 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 SmaCSM2_RS02850 2dc1b2be17c78e7be6db5512029cdccc 127 SMART SM00528 78 124 2.3E-12 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS02850 2dc1b2be17c78e7be6db5512029cdccc 127 Gene3D G3DSA:4.10.430.10 84 124 5.4E-17 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 Gene3D G3DSA:2.40.170.20 170 794 4.7E-80 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 Pfam PF00593 TonB dependent receptor 286 786 3.8E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 Gene3D G3DSA:2.170.130.10 26 169 3.7E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 43 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 SUPERFAMILY SSF56935 36 795 1.68E-115 T 28-03-2018 SmaCSM2_RS16780 b6ca555d8528851ff56c09ad16a02da4 795 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 171 2.7E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS21650 382545cd5a0b482acd387986df4171cf 103 SUPERFAMILY SSF52091 13 94 3.92E-12 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS21650 382545cd5a0b482acd387986df4171cf 103 Gene3D G3DSA:3.30.750.24 12 102 1.2E-8 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS21650 382545cd5a0b482acd387986df4171cf 103 Pfam PF13466 STAS domain 14 90 2.5E-17 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 Pfam PF05706 Cyclin-dependent kinase inhibitor 3 (CDKN3) 9 145 1.4E-7 T 28-03-2018 IPR022778 CDKN3 domain GO:0004721|GO:0004725 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 Gene3D G3DSA:3.90.190.10 22 186 2.4E-17 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 SMART SM00404 83 183 0.0048 T 28-03-2018 IPR003595 Protein-tyrosine phosphatase, catalytic SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 PRINTS PR00700 Protein tyrosine phosphatase signature 151 166 7.4E-6 T 28-03-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 PRINTS PR00700 Protein tyrosine phosphatase signature 124 142 7.4E-6 T 28-03-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 PRINTS PR00700 Protein tyrosine phosphatase signature 167 177 7.4E-6 T 28-03-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 SmaCSM2_RS00170 45e6c740085aec40a7402a29e403ba59 195 SUPERFAMILY SSF52799 37 180 6.67E-29 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS07055 095a6ec91a188c4138988a3e95f744db 280 Gene3D G3DSA:1.10.3720.10 9 270 8.3E-41 T 28-03-2018 SmaCSM2_RS07055 095a6ec91a188c4138988a3e95f744db 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 254 1.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS07055 095a6ec91a188c4138988a3e95f744db 280 SUPERFAMILY SSF161098 14 253 6.54E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 Pfam PF01431 Peptidase family M13 500 700 4.8E-62 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 Pfam PF05649 Peptidase family M13 65 448 2.6E-92 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 SUPERFAMILY SSF55486 50 703 1.37E-196 T 28-03-2018 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 602 613 2.9E-18 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 510 522 2.9E-18 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 492 504 2.9E-18 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 531 547 2.9E-18 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 Gene3D G3DSA:3.40.390.10 57 299 2.8E-13 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS02345 0dd312af1e8982ac33f5bc0ff6698946 703 Gene3D G3DSA:3.40.390.10 367 703 5.2E-101 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 Gene3D G3DSA:1.20.1330.10 211 366 3.4E-28 T 28-03-2018 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 Gene3D G3DSA:1.20.1330.10 40 210 3.5E-45 T 28-03-2018 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.3E-40 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 SUPERFAMILY SSF64518 1 394 1.31E-100 T 28-03-2018 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 PRINTS PR00207 Flagellin signature 76 95 1.3E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 PRINTS PR00207 Flagellin signature 37 54 1.3E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 PRINTS PR00207 Flagellin signature 111 134 1.3E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10240 0f629ef8da0949a6a270d68655fadaf1 394 Pfam PF00700 Bacterial flagellin C-terminal helical region 308 393 4.3E-28 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 Gene3D G3DSA:3.40.50.720 1 194 8.2E-38 T 28-03-2018 SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 SUPERFAMILY SSF51735 139 309 2.91E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 9 139 1.1E-32 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 354 7.5E-63 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 SMART SM01003 6 139 9.2E-42 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 Gene3D G3DSA:3.40.50.720 199 357 1.6E-34 T 28-03-2018 SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 SUPERFAMILY SSF52283 9 170 6.29E-39 T 28-03-2018 SmaCSM2_RS03715 a05ca6a8d7a246a34d7a5c1d64f7f214 359 SMART SM01002 148 310 2.9E-77 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 Gene3D G3DSA:1.10.287.110 1 123 3.5E-31 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 SMART SM00271 4 61 1.3E-26 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 Gene3D G3DSA:2.60.260.20 137 196 4.8E-13 T 28-03-2018 SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 Pfam PF01556 DnaJ C terminal domain 142 275 1.3E-26 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 PRINTS PR00625 DnaJ domain signature 25 40 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 PRINTS PR00625 DnaJ domain signature 61 80 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 PRINTS PR00625 DnaJ domain signature 7 25 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 PRINTS PR00625 DnaJ domain signature 41 61 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 Gene3D G3DSA:2.60.260.20 199 296 1.8E-20 T 28-03-2018 SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 SUPERFAMILY SSF49493 137 211 7.19E-12 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 SUPERFAMILY SSF46565 1 104 1.3E-30 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 Pfam PF00226 DnaJ domain 5 66 5.8E-24 T 28-03-2018 IPR001623 DnaJ domain SmaCSM2_RS16150 a922a59e5ac7fc667c6da87fc2461444 297 SUPERFAMILY SSF49493 204 286 7.72E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SmaCSM2_RS05215 76944bf8c02fc0c4fd7d825d35a8456b 132 Gene3D G3DSA:1.10.150.20 13 66 9.3E-5 T 28-03-2018 SmaCSM2_RS05215 76944bf8c02fc0c4fd7d825d35a8456b 132 Pfam PF12836 Helix-hairpin-helix motif 46 109 9.6E-20 T 28-03-2018 SmaCSM2_RS05215 76944bf8c02fc0c4fd7d825d35a8456b 132 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 49 110 1.3E-22 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain SmaCSM2_RS05215 76944bf8c02fc0c4fd7d825d35a8456b 132 Gene3D G3DSA:1.10.150.310 67 120 2.4E-13 T 28-03-2018 SmaCSM2_RS05215 76944bf8c02fc0c4fd7d825d35a8456b 132 SUPERFAMILY SSF47781 43 111 9.89E-23 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 1.7E-6 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.7E-6 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 391 4.6E-125 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 Gene3D G3DSA:2.40.30.10 201 270 1.3E-22 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 Gene3D G3DSA:3.50.50.60 1 200 2.3E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 SUPERFAMILY SSF51905 337 392 2.53E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 SUPERFAMILY SSF51905 5 190 2.53E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 Pfam PF03486 HI0933-like protein 6 391 1.4E-145 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.7E-5 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 7.7E-5 T 28-03-2018 SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 Gene3D G3DSA:1.10.8.260 271 321 1.0E-15 T 28-03-2018 IPR023166 HI0933 insert-like domain SmaCSM2_RS08860 f0999cfbb38381cdd3093a633ea272a0 394 SUPERFAMILY SSF160996 192 338 6.02E-36 T 28-03-2018 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 PIRSF PIRSF006630 1 269 1.4E-69 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 PIRSF PIRSF006630 257 544 1.1E-110 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 Gene3D G3DSA:3.40.50.620 266 544 3.6E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 37 52 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 SUPERFAMILY SSF52402 268 527 2.21E-74 T 28-03-2018 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 SUPERFAMILY SSF56317 1 250 3.4E-61 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 TIGRFAM TIGR00552 nadE: NAD+ synthetase 276 524 1.6E-57 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 Pfam PF00795 Carbon-nitrogen hydrolase 5 245 3.5E-25 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 Pfam PF02540 NAD synthase 269 519 1.4E-68 T 28-03-2018 IPR022310 NAD/GMP synthase SmaCSM2_RS16895 000f4603559e7d0899b9a202e6d46dbe 544 Gene3D G3DSA:3.60.110.10 1 252 2.7E-59 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 25 105 4.4E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 25 45 2.9E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 63 81 2.9E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 Pfam PF02699 Preprotein translocase subunit 27 102 2.3E-30 T 28-03-2018 IPR003849 Preprotein translocase YajC SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 SMART SM01323 23 105 1.2E-45 T 28-03-2018 IPR003849 Preprotein translocase YajC SmaCSM2_RS08830 4752298bc0e86f210fb0a2ec0d163286 114 Gene3D G3DSA:2.40.33.10 42 104 5.5E-4 T 28-03-2018 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Pfam PF01103 Surface antigen 309 595 4.6E-33 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Pfam PF07244 Surface antigen variable number repeat 124 196 2.1E-5 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Gene3D G3DSA:3.10.20.310 29 116 0.038 T 28-03-2018 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Pfam PF17243 POTRA domain TamA domain 1 33 113 3.6E-17 T 28-03-2018 IPR035243 TamA, POTRA domain 1 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Gene3D G3DSA:3.10.20.310 117 203 1.2E-15 T 28-03-2018 SmaCSM2_RS21425 3583dd58903d0d5cd775bcdf069396d1 598 Gene3D G3DSA:2.40.160.50 235 597 1.5E-63 T 28-03-2018 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 Gene3D G3DSA:3.30.870.10 85 293 4.5E-37 T 28-03-2018 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 Pfam PF13091 PLD-like domain 134 247 1.3E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 Pfam PF13091 PLD-like domain 329 457 8.6E-27 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 69 8.7E-7 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 SUPERFAMILY SSF56024 270 461 8.75E-44 T 28-03-2018 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 19 486 9.2E-110 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 Gene3D G3DSA:3.30.870.10 307 465 7.5E-28 T 28-03-2018 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 SMART SM00155 400 427 5.2E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 SMART SM00155 219 246 6.0E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS00060 2463977b13680bd863cd3745bcf20413 486 SUPERFAMILY SSF56024 89 317 1.19E-49 T 28-03-2018 SmaCSM2_RS01055 7e40f67e508a5b723bb2cf2f4e2ef1f1 172 SUPERFAMILY SSF46626 65 169 8.13E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS01055 7e40f67e508a5b723bb2cf2f4e2ef1f1 172 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 90 167 3.5E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS01055 7e40f67e508a5b723bb2cf2f4e2ef1f1 172 Gene3D G3DSA:1.10.760.10 63 170 7.2E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.6E-16 T 28-03-2018 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.6E-16 T 28-03-2018 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.6E-16 T 28-03-2018 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.6E-16 T 28-03-2018 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 Pfam PF01494 FAD binding domain 6 340 1.1E-26 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 SUPERFAMILY SSF51905 270 378 3.15E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 SUPERFAMILY SSF51905 6 168 3.15E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15885 c86c89e2e50e5c423d9f9732de363157 422 Gene3D G3DSA:3.50.50.60 6 356 8.2E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 SMART SM00344 7 116 3.1E-35 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 5.1E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 Pfam PF01037 Lrp/AsnC ligand binding domain 73 146 5.4E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 Gene3D G3DSA:3.30.70.920 59 157 4.5E-20 T 28-03-2018 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 Gene3D G3DSA:1.10.10.10 1 55 1.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 SUPERFAMILY SSF46785 6 66 4.37E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 3.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 3.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 3.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SmaCSM2_RS18135 726ae11da2af5f5c4f22b0472ec4e300 160 SUPERFAMILY SSF54909 68 150 1.01E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 Gene3D G3DSA:3.40.190.10 91 180 4.4E-13 T 28-03-2018 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 Gene3D G3DSA:3.40.190.10 181 257 1.3E-7 T 28-03-2018 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 Gene3D G3DSA:1.10.10.10 2 86 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 Pfam PF03466 LysR substrate binding domain 91 282 7.2E-24 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 SUPERFAMILY SSF53850 92 282 3.72E-27 T 28-03-2018 SmaCSM2_RS12655 2914971feb0fe614570dc15913484528 283 SUPERFAMILY SSF46785 6 82 3.96E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16575 36ce7e427682488776e1fa0672b11c20 336 Gene3D G3DSA:2.40.128.130 146 334 1.2E-4 T 28-03-2018 SmaCSM2_RS16575 36ce7e427682488776e1fa0672b11c20 336 Pfam PF05275 Copper resistance protein B precursor (CopB) 135 336 5.1E-83 T 28-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 SmaCSM2_RS16575 36ce7e427682488776e1fa0672b11c20 336 SUPERFAMILY SSF103515 162 332 6.93E-5 T 28-03-2018 IPR005546 Autotransporter beta-domain SmaCSM2_RS06470 dcf45ae891aaf7639abf84b27e8d9bd0 315 Pfam PF00892 EamA-like transporter family 147 289 5.1E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06470 dcf45ae891aaf7639abf84b27e8d9bd0 315 Pfam PF00892 EamA-like transporter family 16 138 1.1E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06470 dcf45ae891aaf7639abf84b27e8d9bd0 315 SUPERFAMILY SSF103481 203 293 1.83E-9 T 28-03-2018 SmaCSM2_RS06470 dcf45ae891aaf7639abf84b27e8d9bd0 315 SUPERFAMILY SSF103481 44 139 1.7E-7 T 28-03-2018 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 Gene3D G3DSA:3.40.50.1820 41 316 1.9E-70 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 3.2E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 104 3.2E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 259 273 3.2E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 Pfam PF00561 alpha/beta hydrolase fold 63 296 1.5E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00412 Epoxide hydrolase signature 257 273 2.0E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00412 Epoxide hydrolase signature 69 87 2.0E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00412 Epoxide hydrolase signature 291 313 2.0E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 PRINTS PR00412 Epoxide hydrolase signature 89 104 2.0E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS11205 f83a2ad79ff7d1f80d1f15ae64986724 317 SUPERFAMILY SSF53474 43 316 3.75E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS18585 4697489a9d86dc8f581553a58d0b3338 142 Gene3D G3DSA:3.10.180.10 4 140 4.2E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18585 4697489a9d86dc8f581553a58d0b3338 142 SUPERFAMILY SSF54593 12 130 2.01E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18585 4697489a9d86dc8f581553a58d0b3338 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 125 2.4E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS04300 5d6fe2473710b92892f5cdddd93be7e5 179 Pfam PF01569 PAP2 superfamily 67 175 1.1E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS04300 5d6fe2473710b92892f5cdddd93be7e5 179 SMART SM00014 63 172 7.6E-13 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS04300 5d6fe2473710b92892f5cdddd93be7e5 179 Gene3D G3DSA:1.20.144.10 7 175 6.3E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS04300 5d6fe2473710b92892f5cdddd93be7e5 179 SUPERFAMILY SSF48317 14 176 2.09E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS14045 493532d326596ddc10a4c0f1acff510c 80 Gene3D G3DSA:1.20.5.300 11 57 2.6E-12 T 28-03-2018 SmaCSM2_RS14045 493532d326596ddc10a4c0f1acff510c 80 Hamap MF_00715 Protein SlyX [slyX]. 12 80 14.249 T 28-03-2018 IPR007236 SlyX SmaCSM2_RS14045 493532d326596ddc10a4c0f1acff510c 80 Pfam PF04102 SlyX 13 80 1.7E-15 T 28-03-2018 IPR007236 SlyX SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 12 475 17.612 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 Pfam PF00361 Proton-conducting membrane transporter 130 421 1.1E-72 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 312 324 5.4E-5 T 28-03-2018 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 5.4E-5 T 28-03-2018 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 417 436 5.4E-5 T 28-03-2018 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 5.4E-5 T 28-03-2018 SmaCSM2_RS15110 578e4c35fdfbe5f22122bb1ad3e0cdae 486 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 17 474 1.1E-135 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 SMART SM00830 48 129 6.6E-28 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Pfam PF01817 Chorismate mutase type II 48 127 4.7E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 PIRSF PIRSF001500 38 398 1.2E-136 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Pfam PF00800 Prephenate dehydratase 131 307 4.6E-57 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 SUPERFAMILY SSF48600 44 132 1.68E-19 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 TIGRFAM TIGR01807 CM_P2: chorismate mutase 44 119 5.0E-23 T 28-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Gene3D G3DSA:3.40.190.10 216 295 1.9E-19 T 28-03-2018 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 SUPERFAMILY SSF53850 130 314 4.45E-52 T 28-03-2018 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Gene3D G3DSA:3.40.190.10 136 215 8.1E-30 T 28-03-2018 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Gene3D G3DSA:1.20.59.10 40 135 2.4E-32 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Gene3D G3DSA:3.30.70.260 307 399 2.8E-29 T 28-03-2018 SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 Pfam PF01842 ACT domain 317 382 1.4E-12 T 28-03-2018 IPR002912 ACT domain SmaCSM2_RS13640 e7d223dad694917c7d0cf82f776530af 399 SUPERFAMILY SSF55021 301 396 1.52E-28 T 28-03-2018 SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Pfam PF14821 Threonine synthase N terminus 2 76 1.2E-12 T 28-03-2018 IPR029144 Threonine synthase, N-terminal SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Gene3D G3DSA:3.40.50.1100 324 397 1.1E-14 T 28-03-2018 SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Gene3D G3DSA:3.40.50.1100 196 323 4.9E-39 T 28-03-2018 SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 TIGRFAM TIGR00260 thrC: threonine synthase 72 394 7.2E-74 T 28-03-2018 IPR004450 Threonine synthase-like SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Gene3D G3DSA:3.40.50.1100 97 195 1.9E-20 T 28-03-2018 SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Gene3D G3DSA:3.90.1380.10 1 77 1.4E-15 T 28-03-2018 IPR029144 Threonine synthase, N-terminal SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 94 376 6.8E-21 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS09510 12e950edbf5a94a95e27c3689ca819c4 428 SUPERFAMILY SSF53686 1 427 3.27E-119 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS14710 6836e19888b8b097bb4d6dd322eccbd1 310 Gene3D G3DSA:3.40.190.10 8 120 0.49 T 28-03-2018 SmaCSM2_RS14710 6836e19888b8b097bb4d6dd322eccbd1 310 Gene3D G3DSA:3.40.190.10 129 288 3.3E-23 T 28-03-2018 SmaCSM2_RS14710 6836e19888b8b097bb4d6dd322eccbd1 310 SUPERFAMILY SSF53850 35 283 7.48E-25 T 28-03-2018 SmaCSM2_RS14710 6836e19888b8b097bb4d6dd322eccbd1 310 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 42 290 5.9E-52 T 28-03-2018 SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 SUPERFAMILY SSF49785 205 306 9.92E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 SUPERFAMILY SSF48208 562 987 4.54E-37 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 Pfam PF00754 F5/8 type C domain 205 304 1.2E-14 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 Gene3D G3DSA:2.60.120.430 9 190 1.4E-17 T 28-03-2018 SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 Gene3D G3DSA:1.50.10.10 572 933 9.1E-27 T 28-03-2018 SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 SUPERFAMILY SSF49785 28 182 7.23E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS14380 6cfef0e35d69ccf100bb528c15229c88 1055 Gene3D G3DSA:2.60.120.260 192 308 3.1E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS12535 fc27f4358f569c220a83cc881bc1557d 506 Gene3D G3DSA:3.40.30.10 39 72 2.0E-6 T 28-03-2018 SmaCSM2_RS12535 fc27f4358f569c220a83cc881bc1557d 506 SUPERFAMILY SSF52833 36 148 2.43E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS12535 fc27f4358f569c220a83cc881bc1557d 506 Gene3D G3DSA:3.40.30.10 73 156 1.6E-13 T 28-03-2018 SmaCSM2_RS12535 fc27f4358f569c220a83cc881bc1557d 506 Pfam PF13899 Thioredoxin-like 42 125 2.4E-14 T 28-03-2018 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 Pfam PF13602 Zinc-binding dehydrogenase 192 332 1.7E-22 T 28-03-2018 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 SUPERFAMILY SSF50129 1 144 3.14E-34 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 SUPERFAMILY SSF51735 116 284 7.56E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 89 5.6E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 148 169 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 Gene3D G3DSA:3.40.50.720 139 299 9.8E-23 T 28-03-2018 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 SMART SM00829 10 332 5.8E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 Gene3D G3DSA:3.90.180.10 1 138 3.1E-34 T 28-03-2018 SmaCSM2_RS21680 3c2bd757ceadaa443aa7de2eea85807b 335 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 335 1.2E-159 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 SmaCSM2_RS01155 a936f73fda606ceb4c22c3ff23542fb7 469 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 172 411 4.8E-71 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SmaCSM2_RS01155 a936f73fda606ceb4c22c3ff23542fb7 469 Gene3D G3DSA:3.20.140.10 2 434 6.0E-84 T 28-03-2018 SmaCSM2_RS01155 a936f73fda606ceb4c22c3ff23542fb7 469 PIRSF PIRSF005943 1 469 6.7E-195 T 28-03-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 SmaCSM2_RS01155 a936f73fda606ceb4c22c3ff23542fb7 469 SUPERFAMILY SSF51690 141 467 4.12E-51 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.5E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 SUPERFAMILY SSF74731 3 117 1.36E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 Pfam PF00453 Ribosomal protein L20 3 109 2.6E-47 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.447 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 Gene3D G3DSA:1.10.1900.20 55 116 3.6E-28 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-21 T 28-03-2018 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.7E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.7E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15020 985d62a3a16410f4948284327be6b815 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.7E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS07990 a8ba71c276b27133fa4ff2837746c19b 498 Gene3D G3DSA:3.40.50.1820 39 486 2.3E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS07990 a8ba71c276b27133fa4ff2837746c19b 498 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 203 210 - T 28-03-2018 IPR018202 Serine carboxypeptidase, serine active site SmaCSM2_RS07990 a8ba71c276b27133fa4ff2837746c19b 498 SUPERFAMILY SSF53474 51 485 8.99E-72 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS07990 a8ba71c276b27133fa4ff2837746c19b 498 Pfam PF00450 Serine carboxypeptidase 91 462 8.5E-19 T 28-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 TIGRFAM TIGR02053 MerA: mercury(II) reductase 100 561 2.8E-189 T 28-03-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Gene3D G3DSA:3.50.50.60 255 305 5.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PIRSF PIRSF000350 1 561 3.8E-266 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 437 545 1.4E-29 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 SUPERFAMILY SSF51905 98 427 7.09E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Gene3D G3DSA:3.30.70.100 1 69 3.9E-19 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Gene3D G3DSA:3.50.50.60 306 435 1.4E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Gene3D G3DSA:3.50.50.60 96 254 7.7E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 133 143 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 SUPERFAMILY SSF55424 436 559 2.58E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 237 254 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 534 553 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 292 307 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 110 128 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 13 23 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 272 289 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 145 164 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 PRINTS PR00945 Mercuric reductase class II signature 469 489 2.8E-93 T 28-03-2018 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 SUPERFAMILY SSF55008 2 68 1.7E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 100 418 1.1E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Pfam PF00403 Heavy-metal-associated domain 5 62 9.5E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10730 fbfde6c0560d1e0fb7a6acff860103e1 561 Gene3D G3DSA:3.30.390.30 436 561 6.7E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 20 258 3.5E-59 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 Pfam PF01311 Bacterial export proteins, family 1 20 253 5.9E-59 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 209 228 2.6E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 27 48 2.6E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 187 209 2.6E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 SmaCSM2_RS10120 b467bd1b3d7f0e721323db1b461ff93a 263 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 86 105 2.6E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 18 123 2.8E-34 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 142 159 7.7E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 210 221 7.7E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 199 209 7.7E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 222 237 7.7E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SmaCSM2_RS16945 289a63ae37ca27e8862fb9e45c6b46d3 287 Pfam PF01478 Type IV leader peptidase family 133 241 1.8E-24 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 SmaCSM2_RS16680 c6f1f4aff6509d8b9625024a848adcfa 350 SUPERFAMILY SSF74653 258 347 1.12E-9 T 28-03-2018 SmaCSM2_RS16680 c6f1f4aff6509d8b9625024a848adcfa 350 TIGRFAM TIGR02794 tolA_full: protein TolA 19 345 1.0E-34 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS16680 c6f1f4aff6509d8b9625024a848adcfa 350 Gene3D G3DSA:3.30.1150.10 279 345 4.5E-10 T 28-03-2018 SmaCSM2_RS16680 c6f1f4aff6509d8b9625024a848adcfa 350 Pfam PF13103 TonB C terminal 262 333 7.1E-11 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS16680 c6f1f4aff6509d8b9625024a848adcfa 350 Gene3D G3DSA:3.40.50.300 41 278 9.2E-4 T 28-03-2018 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 Gene3D G3DSA:3.90.1150.10 251 363 5.8E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 Pfam PF00155 Aminotransferase class I and II 49 357 4.3E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 11 361 52.259 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 Gene3D G3DSA:3.40.640.10 51 250 2.8E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 358 4.0E-103 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SmaCSM2_RS09545 70584132307fcd610e4cdaa90d1b0b1c 364 SUPERFAMILY SSF53383 27 358 5.84E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 195 2.2E-25 T 28-03-2018 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-7 T 28-03-2018 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 1.2E-7 T 28-03-2018 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.2E-7 T 28-03-2018 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 1.6E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 1.6E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.6E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 SUPERFAMILY SSF51905 3 204 5.57E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 Gene3D G3DSA:3.50.50.60 149 280 5.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 SUPERFAMILY SSF51905 229 351 3.5E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 SUPERFAMILY SSF51905 158 198 3.5E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS20170 83a6522745f6d66007d0cfc087586913 361 Gene3D G3DSA:3.50.50.60 3 148 8.2E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02340 6bcf7006b90d860fbfca4df57fee8bec 390 SUPERFAMILY SSF103473 7 389 3.79E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS02340 6bcf7006b90d860fbfca4df57fee8bec 390 Pfam PF07690 Major Facilitator Superfamily 25 355 2.1E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS02340 6bcf7006b90d860fbfca4df57fee8bec 390 Gene3D G3DSA:1.20.1250.20 9 201 1.0E-22 T 28-03-2018 SmaCSM2_RS02340 6bcf7006b90d860fbfca4df57fee8bec 390 Gene3D G3DSA:1.20.1250.20 202 390 1.3E-14 T 28-03-2018 SmaCSM2_RS07220 67eaa8c83717d7cb691ab0f1399f72e0 171 SUPERFAMILY SSF54523 9 146 2.35E-18 T 28-03-2018 SmaCSM2_RS07220 67eaa8c83717d7cb691ab0f1399f72e0 171 Gene3D G3DSA:3.30.700.10 9 171 1.3E-15 T 28-03-2018 SmaCSM2_RS07220 67eaa8c83717d7cb691ab0f1399f72e0 171 Pfam PF12019 Type II transport protein GspH 46 161 1.5E-9 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS07220 67eaa8c83717d7cb691ab0f1399f72e0 171 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 29 8.6E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07220 67eaa8c83717d7cb691ab0f1399f72e0 171 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 29 1.4E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12875 b965847b533788cf49e2b37155eb7fb0 211 SUPERFAMILY SSF55729 36 198 1.51E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS12875 b965847b533788cf49e2b37155eb7fb0 211 Gene3D G3DSA:3.40.630.30 32 205 6.5E-10 T 28-03-2018 SmaCSM2_RS12875 b965847b533788cf49e2b37155eb7fb0 211 Pfam PF13420 Acetyltransferase (GNAT) domain 43 194 3.8E-22 T 28-03-2018 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 SUPERFAMILY SSF51905 7 178 5.75E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 SUPERFAMILY SSF51905 268 387 5.75E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 Gene3D G3DSA:3.50.50.60 5 366 5.5E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 Pfam PF01494 FAD binding domain 7 324 2.2E-34 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.6E-20 T 28-03-2018 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 3.6E-20 T 28-03-2018 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 3.6E-20 T 28-03-2018 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 3.6E-20 T 28-03-2018 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 392 1.6E-129 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS03595 191ac597441292ca4b16fc187e57151f 393 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 459 2.6E-57 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 Gene3D G3DSA:3.30.43.10 1 92 3.8E-25 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 SUPERFAMILY SSF55103 191 461 7.85E-59 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 SUPERFAMILY SSF56176 4 216 1.78E-67 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 Pfam PF01565 FAD binding domain 40 178 1.3E-37 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 Gene3D G3DSA:1.10.45.10 420 459 3.5E-15 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SmaCSM2_RS09710 2874671605d71bf9d3848ec36d16f727 462 Gene3D G3DSA:3.30.465.10 93 239 6.2E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS14855 42434cfbee7963acd86c047df5b8f29b 158 SUPERFAMILY SSF117070 10 130 1.31E-6 T 28-03-2018 SmaCSM2_RS14855 42434cfbee7963acd86c047df5b8f29b 158 Pfam PF03168 Late embryogenesis abundant protein 50 142 7.0E-7 T 28-03-2018 IPR004864 Late embryogenesis abundant protein, LEA-14 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 400 8.6E-141 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 PIRSF PIRSF000429 2 402 1.6E-127 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 Pfam PF02803 Thiolase, C-terminal domain 279 400 6.4E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 SUPERFAMILY SSF53901 4 276 5.76E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 Pfam PF00108 Thiolase, N-terminal domain 9 272 3.5E-74 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 Gene3D G3DSA:3.40.47.10 282 399 1.4E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 SUPERFAMILY SSF53901 280 400 2.02E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS09025 b076c58f6e494ba7a6bef32b20baba36 402 Gene3D G3DSA:3.40.47.10 1 281 1.9E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:3.30.70.1430 38 139 9.7E-25 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1031 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82714 182 272 3.14E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82866 296 494 1.7E-44 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 38 131 1.88E-23 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 677 726 3.66E-23 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 813 861 3.66E-23 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 629 643 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 4.8E-103 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82714 727 812 1.31E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 575 676 1.27E-27 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 136 182 1.92E-20 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82693 274 329 1.92E-20 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:3.30.2090.10 180 273 8.2E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 SUPERFAMILY SSF82866 839 1031 9.42E-43 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:3.30.2090.10 726 813 1.3E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:1.20.1640.10 274 500 1.7E-40 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:1.20.1640.10 819 1034 1.2E-38 T 28-03-2018 SmaCSM2_RS20700 45a7046a26ffb472ff09333d52d375dd 1049 Gene3D G3DSA:3.30.70.1430 577 676 3.8E-22 T 28-03-2018 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SMART SM00490 460 546 1.1E-20 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Gene3D G3DSA:3.40.50.300 11 413 4.4E-30 T 28-03-2018 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 669 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Gene3D G3DSA:3.40.50.300 415 589 1.1E-31 T 28-03-2018 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Pfam PF02151 UvrB/uvrC motif 638 670 2.5E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SUPERFAMILY SSF46600 625 671 3.92E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SMART SM00487 9 426 1.0E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SUPERFAMILY SSF52540 4 415 1.0E-131 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Pfam PF12344 Ultra-violet resistance protein B 552 593 5.7E-22 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SUPERFAMILY SSF52540 459 584 1.54E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 SUPERFAMILY SSF52540 37 82 1.54E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Pfam PF00271 Helicase conserved C-terminal domain 441 544 6.9E-18 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 671 42.805 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Gene3D G3DSA:4.10.860.10 615 674 6.6E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 SmaCSM2_RS07260 2448e01659c926acce69b8a94e161073 674 Pfam PF04851 Type III restriction enzyme, res subunit 16 97 1.1E-8 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 Gene3D G3DSA:3.30.70.1070 98 171 1.4E-10 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 SUPERFAMILY SSF110997 98 159 1.31E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 Gene3D G3DSA:3.30.70.1070 264 343 3.8E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 Pfam PF05036 Sporulation related domain 268 341 2.9E-17 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 Pfam PF05036 Sporulation related domain 96 172 5.7E-14 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS04265 211e2c1c6cfe929ed3b63345bdeb56cb 344 SUPERFAMILY SSF110997 267 341 2.09E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS03300 f2665a9d79c113e51252a30221576c70 318 SUPERFAMILY SSF51261 168 304 1.52E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS03300 f2665a9d79c113e51252a30221576c70 318 Gene3D G3DSA:2.70.70.10 52 306 3.2E-46 T 28-03-2018 SmaCSM2_RS03300 f2665a9d79c113e51252a30221576c70 318 Pfam PF01551 Peptidase family M23 206 300 3.4E-32 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS21345 770870b8e703e372b43d8c081fb7913a 265 PIRSF PIRSF009320 88 261 1.5E-9 T 28-03-2018 SmaCSM2_RS21345 770870b8e703e372b43d8c081fb7913a 265 PIRSF PIRSF009320 2 82 1.0E-15 T 28-03-2018 SmaCSM2_RS21345 770870b8e703e372b43d8c081fb7913a 265 SUPERFAMILY SSF52540 1 253 2.84E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21345 770870b8e703e372b43d8c081fb7913a 265 Gene3D G3DSA:3.40.50.300 1 265 1.3E-60 T 28-03-2018 SmaCSM2_RS21345 770870b8e703e372b43d8c081fb7913a 265 Pfam PF13614 AAA domain 3 177 5.8E-65 T 28-03-2018 IPR025669 AAA domain SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 153 2.2E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 Gene3D G3DSA:2.40.170.20 165 687 6.1E-56 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 Gene3D G3DSA:2.170.130.10 29 164 1.0E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 46 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 55 687 6.2E-252 T 28-03-2018 IPR010100 TonB-dependent copper receptor SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 Pfam PF00593 TonB dependent receptor 209 686 1.6E-43 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17110 59ddecc14d5dbe51353644757a4dadc0 687 SUPERFAMILY SSF56935 29 687 2.75E-90 T 28-03-2018 SmaCSM2_RS10545 69e417c74ae75bc5166ff5ebc384d13a 261 Pfam PF06966 Protein of unknown function (DUF1295) 19 245 9.8E-70 T 28-03-2018 IPR010721 Protein of unknown function DUF1295 SmaCSM2_RS08015 90fe2f5bb9939982ed556c76029c60a2 276 Pfam PF00793 DAHP synthetase I family 8 266 2.3E-68 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS08015 90fe2f5bb9939982ed556c76029c60a2 276 Gene3D G3DSA:3.20.20.70 11 271 9.6E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS08015 90fe2f5bb9939982ed556c76029c60a2 276 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 269 2.6E-129 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS08015 90fe2f5bb9939982ed556c76029c60a2 276 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 52.773 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SmaCSM2_RS08015 90fe2f5bb9939982ed556c76029c60a2 276 SUPERFAMILY SSF51569 2 270 3.76E-108 T 28-03-2018 SmaCSM2_RS20210 5d1128ed30749d9635ad4eed488d4259 135 SUPERFAMILY SSF54427 2 127 4.19E-28 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS20210 5d1128ed30749d9635ad4eed488d4259 135 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 5 132 9.1E-40 T 28-03-2018 IPR011721 Conserved hypothetical protein CHP02096 SmaCSM2_RS20210 5d1128ed30749d9635ad4eed488d4259 135 Pfam PF12680 SnoaL-like domain 8 117 2.2E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SmaCSM2_RS20210 5d1128ed30749d9635ad4eed488d4259 135 Gene3D G3DSA:3.10.450.50 1 135 7.7E-25 T 28-03-2018 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 Pfam PF00107 Zinc-binding dehydrogenase 151 268 3.2E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 SUPERFAMILY SSF51735 114 290 5.65E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 Gene3D G3DSA:3.40.50.720 139 269 9.2E-23 T 28-03-2018 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 Gene3D G3DSA:3.90.180.10 1 138 5.4E-36 T 28-03-2018 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.1E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 SMART SM00829 11 323 5.1E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS12610 c12776d1b9196564c8fa7b3e5352047b 325 SUPERFAMILY SSF50129 1 144 1.52E-33 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 Gene3D G3DSA:1.10.10.10 6 87 4.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 Pfam PF03466 LysR substrate binding domain 91 295 3.5E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 Gene3D G3DSA:3.40.190.10 180 266 1.8E-23 T 28-03-2018 SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 Gene3D G3DSA:3.40.190.10 89 179 7.0E-19 T 28-03-2018 SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.9E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 SUPERFAMILY SSF46785 6 88 1.47E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02205 bafa02f1099d9dd2f651db60e891db0b 299 SUPERFAMILY SSF53850 93 296 3.26E-41 T 28-03-2018 SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 3 171 23.012 T 28-03-2018 IPR006839 Ribosome-associated, YjgA SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 Gene3D G3DSA:1.10.60.30 25 94 7.2E-21 T 28-03-2018 SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 Gene3D G3DSA:1.10.60.30 102 174 2.0E-28 T 28-03-2018 SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 PIRSF PIRSF016183 1 174 1.0E-65 T 28-03-2018 IPR006839 Ribosome-associated, YjgA SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 Pfam PF04751 Protein of unknown function (DUF615) 13 167 6.9E-49 T 28-03-2018 IPR006839 Ribosome-associated, YjgA SmaCSM2_RS15555 14f44da0c8bb4131f1e4cd4de365a88a 195 SUPERFAMILY SSF158710 27 170 7.98E-46 T 28-03-2018 IPR023153 PSPTO4464-like domain SmaCSM2_RS06365 82ebe2e87c47e6b9ec87466b8b843d3f 163 SUPERFAMILY SSF46785 29 159 1.13E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06365 82ebe2e87c47e6b9ec87466b8b843d3f 163 Gene3D G3DSA:1.10.10.10 10 106 4.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06365 82ebe2e87c47e6b9ec87466b8b843d3f 163 Pfam PF01475 Ferric uptake regulator family 32 154 8.0E-12 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SmaCSM2_RS13250 051e450a60dfef30d35edd0c2a17493c 355 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 7 353 1.5E-158 T 28-03-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 SmaCSM2_RS13250 051e450a60dfef30d35edd0c2a17493c 355 SUPERFAMILY SSF53474 34 351 1.22E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13250 051e450a60dfef30d35edd0c2a17493c 355 Pfam PF00561 alpha/beta hydrolase fold 68 330 5.4E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS13250 051e450a60dfef30d35edd0c2a17493c 355 Gene3D G3DSA:3.40.50.1820 53 355 3.1E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS17765 c9d4d6c65a88b0db0f7f9c5af2207b7a 259 Gene3D G3DSA:3.40.50.150 28 259 3.2E-39 T 28-03-2018 SmaCSM2_RS17765 c9d4d6c65a88b0db0f7f9c5af2207b7a 259 Pfam PF13847 Methyltransferase domain 44 138 1.4E-17 T 28-03-2018 IPR025714 Methyltransferase domain SmaCSM2_RS17765 c9d4d6c65a88b0db0f7f9c5af2207b7a 259 SUPERFAMILY SSF53335 22 197 3.16E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS00915 0e4a75b5192039850c300c4be3454129 261 TIGRFAM TIGR04390 OMP_YaiO_dom: outer membrane protein, YaiO family 26 261 1.2E-51 T 28-03-2018 IPR030887 YaiO family, OMP domain SmaCSM2_RS12620 c36a8bef14af0db9cb14a2a37740a64f 659 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 55 504 2.3E-154 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS12620 c36a8bef14af0db9cb14a2a37740a64f 659 ProSitePatterns PS01303 BCCT family of transporters signature. 319 328 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS12620 c36a8bef14af0db9cb14a2a37740a64f 659 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 504 7.4E-177 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08455 4e1711a54e4c366ebb8bfb797063d084 82 Gene3D G3DSA:1.10.150.250 1 81 1.0E-21 T 28-03-2018 SmaCSM2_RS08455 4e1711a54e4c366ebb8bfb797063d084 82 SUPERFAMILY SSF109910 4 79 1.06E-22 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase SmaCSM2_RS08455 4e1711a54e4c366ebb8bfb797063d084 82 Pfam PF03937 Flavinator of succinate dehydrogenase 8 77 4.8E-22 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 SUPERFAMILY SSF53067 190 350 1.3E-25 T 28-03-2018 SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 SUPERFAMILY SSF53067 11 176 1.48E-9 T 28-03-2018 SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 Gene3D G3DSA:3.30.420.40 3 170 1.5E-32 T 28-03-2018 SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 Gene3D G3DSA:3.30.420.40 298 352 1.7E-5 T 28-03-2018 SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 PIRSF PIRSF019169 1 352 4.7E-129 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 8 351 6.7E-142 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 SMART SM00842 11 180 0.0047 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 Pfam PF11104 Type IV pilus assembly protein PilM; 13 351 1.8E-135 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM SmaCSM2_RS17290 a40f1d7223bafaaef009e7578a67e77c 352 Gene3D G3DSA:3.30.420.40 189 297 2.6E-6 T 28-03-2018 SmaCSM2_RS06730 665c9def78aec97de29e9b6164c45c13 775 Gene3D G3DSA:3.60.20.10 254 769 9.5E-83 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS06730 665c9def78aec97de29e9b6164c45c13 775 PIRSF PIRSF001227 6 774 1.7E-148 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 SmaCSM2_RS06730 665c9def78aec97de29e9b6164c45c13 775 SUPERFAMILY SSF56235 42 773 7.72E-165 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS06730 665c9def78aec97de29e9b6164c45c13 775 Pfam PF01804 Penicillin amidase 46 761 6.9E-123 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SmaCSM2_RS06730 665c9def78aec97de29e9b6164c45c13 775 Gene3D G3DSA:1.10.439.10 16 179 7.7E-43 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 173 8.6E-38 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 191 3.8E-25 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Pfam PF01386 Ribosomal L25p family 7 94 2.0E-25 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 5 97 22.842 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Gene3D G3DSA:2.40.240.10 4 97 3.3E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 SUPERFAMILY SSF50715 4 198 1.74E-53 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Gene3D G3DSA:2.170.120.20 101 197 3.6E-26 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 97 2.0E-37 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SmaCSM2_RS03840 838a04e63be8b29429d037a6f8392063 205 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 191 28.922 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 Pfam PF00877 NlpC/P60 family 335 427 1.1E-11 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 Gene3D G3DSA:3.90.1720.10 320 479 4.6E-25 T 28-03-2018 SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 PIRSF PIRSF019015 14 478 5.2E-77 T 28-03-2018 IPR027017 Uncharacterised peptidase with NlpC/P60 domain, YkfC type SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 Pfam PF12913 SH3 domain (SH3b1 type) 169 216 3.2E-15 T 28-03-2018 SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 SUPERFAMILY SSF54001 319 426 9.32E-17 T 28-03-2018 SmaCSM2_RS01930 5f28e783ab5111caea97d76f8bc0fdae 479 Pfam PF12914 SH3 domain of SH3b2 type 224 274 2.5E-7 T 28-03-2018 IPR026864 SH3b2-type SH3 domain SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 471 1.3E-81 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 Gene3D G3DSA:1.20.1600.10 21 477 6.3E-70 T 28-03-2018 SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 Pfam PF02321 Outer membrane efflux protein 71 261 2.4E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 Pfam PF02321 Outer membrane efflux protein 292 462 4.6E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 SUPERFAMILY SSF56954 7 30 2.75E-81 T 28-03-2018 SmaCSM2_RS21600 e5712dfc4a1d9567d46fa06bc2879c34 486 SUPERFAMILY SSF56954 62 473 2.75E-81 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Pfam PF00009 Elongation factor Tu GTP binding domain 5 202 3.0E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 SUPERFAMILY SSF50447 158 306 3.53E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 PRINTS PR00315 GTP-binding elongation factor signature 52 60 5.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 PRINTS PR00315 GTP-binding elongation factor signature 8 21 5.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 PRINTS PR00315 GTP-binding elongation factor signature 130 139 5.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Gene3D G3DSA:3.30.70.870 309 411 7.6E-31 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 146 9.8E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Gene3D G3DSA:2.40.30.10 190 307 2.0E-23 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 SUPERFAMILY SSF52540 3 214 8.77E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Gene3D G3DSA:3.40.50.300 2 189 1.2E-35 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Gene3D G3DSA:2.40.50.250 494 584 1.3E-33 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Pfam PF03144 Elongation factor Tu domain 2 226 296 4.8E-11 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 SUPERFAMILY SSF54980 309 398 2.55E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Pfam PF00679 Elongation factor G C-terminus 407 486 1.2E-22 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 610 3.4E-277 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 Gene3D G3DSA:3.30.70.240 412 492 5.1E-20 T 28-03-2018 SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 SMART SM00838 406 495 5.7E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SmaCSM2_RS04155 a670f4e05529a1024362966552c84419 615 SUPERFAMILY SSF54980 409 522 2.54E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 Pfam PF00037 4Fe-4S binding domain 34 55 1.1E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 SUPERFAMILY SSF54862 2 100 5.24E-24 T 28-03-2018 SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 Gene3D G3DSA:3.30.70.20 46 107 6.1E-10 T 28-03-2018 SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 9.5E-20 T 28-03-2018 IPR022569 Ferredoxin, C-terminal SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 Gene3D G3DSA:3.30.70.20 2 45 3.1E-13 T 28-03-2018 SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.1E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.1E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SmaCSM2_RS08320 f7095e22a88d839fbdee046dbe0a366b 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.1E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 SMART SM00861 595 788 2.8E-54 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 SUPERFAMILY SSF52518 118 523 1.37E-85 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Gene3D G3DSA:3.40.50.970 596 803 2.4E-57 T 28-03-2018 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 11 49 1.4E-15 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Pfam PF00676 Dehydrogenase E1 component 209 514 7.5E-51 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 933 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Pfam PF02779 Transketolase, pyrimidine binding domain 596 789 1.5E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 SUPERFAMILY SSF52518 578 795 7.15E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 793 933 2.3E-51 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 PIRSF PIRSF000157 1 935 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Gene3D G3DSA:1.10.287.1150 81 161 6.1E-18 T 28-03-2018 SmaCSM2_RS14120 9a9725a8f18e04e48dfb58e672ebd798 943 Gene3D G3DSA:3.40.50.970 162 521 1.5E-85 T 28-03-2018 SmaCSM2_RS04150 1d5d4a6abf2200b27e1e294eb6ca4dde 155 Pfam PF09900 Predicted membrane protein (DUF2127) 15 149 6.2E-36 T 28-03-2018 IPR021125 Protein of unknown function DUF2127 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 SUPERFAMILY SSF46689 8 77 2.05E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 SUPERFAMILY SSF48498 83 207 7.04E-30 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 Gene3D G3DSA:1.10.10.60 2 48 1.3E-16 T 28-03-2018 SmaCSM2_RS09035 3196b34f29c8b9045c064572f6370331 217 Gene3D G3DSA:1.10.357.10 49 213 1.1E-30 T 28-03-2018 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 9.4E-27 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 SUPERFAMILY SSF55620 1 116 2.11E-36 T 28-03-2018 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 Gene3D G3DSA:3.30.1130.10 1 117 4.0E-37 T 28-03-2018 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 TIGRFAM TIGR00526 folB_dom: FolB domain 1 116 3.3E-34 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 Pfam PF02152 Dihydroneopterin aldolase 4 113 2.1E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SmaCSM2_RS01875 e9bddbb4833b7ade0ade2b146c483a2b 117 SMART SM00905 4 114 1.4E-49 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SmaCSM2_RS03765 c0b886a46b0890be3fb470f655a62a4e 161 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 3.0E-5 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SmaCSM2_RS03765 c0b886a46b0890be3fb470f655a62a4e 161 PRINTS PR00139 Asparaginase/glutaminase family signature 75 93 3.0E-5 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SmaCSM2_RS03765 c0b886a46b0890be3fb470f655a62a4e 161 Gene3D G3DSA:3.40.50.1170 1 161 9.7E-24 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SmaCSM2_RS03765 c0b886a46b0890be3fb470f655a62a4e 161 Pfam PF00710 Asparaginase, N-terminal 4 155 2.3E-21 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SmaCSM2_RS03765 c0b886a46b0890be3fb470f655a62a4e 161 SUPERFAMILY SSF53774 1 156 1.57E-31 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SmaCSM2_RS00585 30aaffb31d16c49543ad6c9010683c05 263 Gene3D G3DSA:3.40.1130.10 52 262 6.5E-31 T 28-03-2018 SmaCSM2_RS00585 30aaffb31d16c49543ad6c9010683c05 263 SMART SM00563 85 197 6.9E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS00585 30aaffb31d16c49543ad6c9010683c05 263 SUPERFAMILY SSF69593 54 199 3.27E-24 T 28-03-2018 SmaCSM2_RS00585 30aaffb31d16c49543ad6c9010683c05 263 Pfam PF01553 Acyltransferase 83 194 6.1E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 Gene3D G3DSA:3.40.50.300 537 883 2.5E-52 T 28-03-2018 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 Gene3D G3DSA:1.20.1580.10 106 415 4.2E-62 T 28-03-2018 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 Gene3D G3DSA:3.40.50.300 43 57 0.16 T 28-03-2018 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 Gene3D G3DSA:3.40.50.300 7 42 0.18 T 28-03-2018 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 ProSitePatterns PS00211 ABC transporters family signature. 769 783 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 SUPERFAMILY SSF52540 623 853 1.62E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 SUPERFAMILY SSF52540 544 586 1.62E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 SUPERFAMILY SSF52540 156 259 7.28E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 SUPERFAMILY SSF52540 21 102 7.28E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07505 95ec325689722bab9d86c94f77a2b35d 883 SUPERFAMILY SSF52540 358 497 7.28E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 SUPERFAMILY SSF48498 78 185 1.48E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 SUPERFAMILY SSF46689 9 72 6.16E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 Pfam PF16925 Bacterial transcriptional repressor C-terminal 81 186 8.7E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 Gene3D G3DSA:1.10.357.10 51 187 7.2E-18 T 28-03-2018 SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 6.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13745 61118eb04537fc0961722bc9f2dddcc9 191 Gene3D G3DSA:1.10.10.60 1 50 1.5E-11 T 28-03-2018 SmaCSM2_RS17180 5f78525fe05a12c10cc0f0827fd4078c 209 Pfam PF03922 OmpW family 28 209 1.1E-46 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 SmaCSM2_RS17180 5f78525fe05a12c10cc0f0827fd4078c 209 SUPERFAMILY SSF56925 27 209 2.62E-26 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS17180 5f78525fe05a12c10cc0f0827fd4078c 209 Gene3D G3DSA:2.40.160.20 26 209 1.1E-28 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 ProSitePatterns PS00018 EF-hand calcium-binding domain. 98 110 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 SMART SM00054 89 117 0.0071 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 SMART SM00054 28 56 2.9 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 SMART SM00054 63 86 6.9 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 SUPERFAMILY SSF47473 25 115 8.04E-18 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 Gene3D G3DSA:1.10.1330.10 44 87 5.7E-12 T 28-03-2018 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 Pfam PF13499 EF-hand domain pair 30 83 3.7E-9 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 Gene3D G3DSA:1.10.238.10 16 43 0.0014 T 28-03-2018 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 Pfam PF13405 EF-hand domain 90 114 4.2E-5 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS13535 57887570aa6dca8bf65e2be62f768b41 125 Gene3D G3DSA:1.10.238.10 88 123 8.0E-6 T 28-03-2018 SmaCSM2_RS09785 862821cd3b392e3318e1dc22d5ec2fad 84 SUPERFAMILY SSF50037 3 76 5.72E-14 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal SmaCSM2_RS09785 862821cd3b392e3318e1dc22d5ec2fad 84 SMART SM00899 1 77 1.1E-18 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SmaCSM2_RS09785 862821cd3b392e3318e1dc22d5ec2fad 84 Pfam PF04023 FeoA domain 1 76 2.0E-18 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SmaCSM2_RS09785 862821cd3b392e3318e1dc22d5ec2fad 84 Gene3D G3DSA:2.30.30.90 1 84 6.7E-22 T 28-03-2018 SmaCSM2_RS03605 37961dbd3c7d0f4118c22591d7a44187 355 SUPERFAMILY SSF53335 188 298 3.66E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03605 37961dbd3c7d0f4118c22591d7a44187 355 Pfam PF01728 FtsJ-like methyltransferase 189 280 9.2E-7 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SmaCSM2_RS03605 37961dbd3c7d0f4118c22591d7a44187 355 PIRSF PIRSF028774 9 354 1.3E-150 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 SmaCSM2_RS03605 37961dbd3c7d0f4118c22591d7a44187 355 Gene3D G3DSA:3.40.50.150 179 329 2.5E-17 T 28-03-2018 SmaCSM2_RS03605 37961dbd3c7d0f4118c22591d7a44187 355 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 8 354 74.67 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 SmaCSM2_RS01815 2fdc6f49da87e676abe3aca841f853e5 189 SUPERFAMILY SSF52833 66 187 8.21E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 SUPERFAMILY SSF53383 20 440 1.94E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 948 25.662 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Pfam PF02347 Glycine cleavage system P-protein 19 440 2.2E-178 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Pfam PF02347 Glycine cleavage system P-protein 446 732 1.3E-12 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Gene3D G3DSA:3.40.640.10 526 763 3.6E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Gene3D G3DSA:3.40.640.10 98 343 1.6E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Gene3D G3DSA:3.90.1150.10 344 444 3.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 Gene3D G3DSA:3.90.1150.10 764 897 6.6E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 SUPERFAMILY SSF53383 921 943 7.03E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 SUPERFAMILY SSF53383 468 878 7.03E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS16065 b107ff57c9fb0d704ed2d58f39154f8b 955 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 942 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 283 413 2.5E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 51 207 2.5E-5 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 SUPERFAMILY SSF55073 282 448 2.67E-11 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 Gene3D G3DSA:3.30.70.1230 33 212 2.7E-11 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 Gene3D G3DSA:3.30.70.1230 277 472 4.1E-11 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS04695 4462f7606dacb77c1e8a2ab473e61c87 515 SUPERFAMILY SSF55073 44 205 3.77E-15 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 Gene3D G3DSA:3.40.50.2020 273 442 1.6E-31 T 28-03-2018 SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 463 7.0E-162 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 SUPERFAMILY SSF53271 248 473 1.88E-69 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 Gene3D G3DSA:3.60.20.10 2 255 7.9E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 SUPERFAMILY SSF56235 2 255 1.2E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 Pfam PF13522 Glutamine amidotransferase domain 58 206 1.2E-16 T 28-03-2018 SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 462 45.524 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SmaCSM2_RS04275 3a35025d5082309c180568c2f9c6cc28 488 PIRSF PIRSF000485 1 476 1.0E-156 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 456 2.4E-112 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 Pfam PF04963 Sigma-54 factor, core binding domain 115 290 1.3E-33 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 Gene3D G3DSA:1.10.10.10 307 399 9.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 437 444 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 3.6E-13 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 349 368 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 PIRSF PIRSF000774 1 459 1.0E-117 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 Pfam PF04552 Sigma-54, DNA binding domain 304 457 3.1E-56 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 PRINTS PR00045 Sigma-54 factor signature 377 388 3.4E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 PRINTS PR00045 Sigma-54 factor signature 432 450 3.4E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 PRINTS PR00045 Sigma-54 factor signature 173 190 3.4E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS10205 f68bfcce425af1df190d2a48dc4aadcb 469 PRINTS PR00045 Sigma-54 factor signature 361 373 3.4E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17485 16e0ef67096cd48d570e1cf3630077c5 98 SUPERFAMILY SSF102829 6 94 8.24E-23 T 28-03-2018 IPR007838 Cell division protein ZapA-like SmaCSM2_RS17485 16e0ef67096cd48d570e1cf3630077c5 98 Pfam PF05164 Cell division protein ZapA 6 90 6.3E-20 T 28-03-2018 IPR007838 Cell division protein ZapA-like SmaCSM2_RS05050 9f41e80bfc948726d0774e636610f92f 271 SUPERFAMILY SSF53474 35 268 6.27E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05050 9f41e80bfc948726d0774e636610f92f 271 Gene3D G3DSA:3.40.50.1820 30 271 1.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05050 9f41e80bfc948726d0774e636610f92f 271 Pfam PF00326 Prolyl oligopeptidase family 126 253 1.0E-8 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS03885 7717124b848181a91bedccd497d2aff7 339 Pfam PF03575 Peptidase family S51 121 176 1.2E-10 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 SmaCSM2_RS03885 7717124b848181a91bedccd497d2aff7 339 Gene3D G3DSA:3.40.50.880 51 323 8.9E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS03885 7717124b848181a91bedccd497d2aff7 339 SUPERFAMILY SSF52317 61 281 8.09E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS03885 7717124b848181a91bedccd497d2aff7 339 PIRSF PIRSF032067 3 316 1.1E-57 T 28-03-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 SmaCSM2_RS10250 80b41dc6e1ac65ed2e29a4cad458ac83 400 Gene3D G3DSA:1.20.1330.10 40 374 2.2E-23 T 28-03-2018 SmaCSM2_RS10250 80b41dc6e1ac65ed2e29a4cad458ac83 400 SUPERFAMILY SSF64518 1 400 2.88E-71 T 28-03-2018 SmaCSM2_RS10250 80b41dc6e1ac65ed2e29a4cad458ac83 400 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 6.3E-20 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10250 80b41dc6e1ac65ed2e29a4cad458ac83 400 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 397 3.2E-99 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 SmaCSM2_RS10250 80b41dc6e1ac65ed2e29a4cad458ac83 400 Pfam PF00700 Bacterial flagellin C-terminal helical region 318 397 5.6E-5 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS20590 320e70c52fd08219b4e5f417e3355a67 312 Gene3D G3DSA:3.30.420.40 124 311 2.7E-47 T 28-03-2018 SmaCSM2_RS20590 320e70c52fd08219b4e5f417e3355a67 312 Pfam PF00480 ROK family 9 307 1.5E-64 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SmaCSM2_RS20590 320e70c52fd08219b4e5f417e3355a67 312 Gene3D G3DSA:3.30.420.40 5 123 6.2E-24 T 28-03-2018 SmaCSM2_RS20590 320e70c52fd08219b4e5f417e3355a67 312 SUPERFAMILY SSF53067 10 308 8.99E-57 T 28-03-2018 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 176 1.0E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 Gene3D G3DSA:2.40.170.20 189 990 4.7E-69 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 Pfam PF00593 TonB dependent receptor 373 989 1.9E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 Gene3D G3DSA:2.170.130.10 55 188 6.4E-32 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 SUPERFAMILY SSF56935 802 990 1.2E-99 T 28-03-2018 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 SUPERFAMILY SSF56935 34 240 1.2E-99 T 28-03-2018 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 SUPERFAMILY SSF56935 415 647 1.2E-99 T 28-03-2018 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 SUPERFAMILY SSF56935 322 373 1.2E-99 T 28-03-2018 SmaCSM2_RS20575 b375a6416a2693c811e124056af0f932 991 SUPERFAMILY SSF56935 705 749 1.2E-99 T 28-03-2018 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Gene3D G3DSA:3.40.1770.10 8 150 1.8E-28 T 28-03-2018 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Gene3D G3DSA:3.40.1770.10 194 553 2.4E-161 T 28-03-2018 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Pfam PF17391 Urocanase N-terminal domain 10 136 9.6E-61 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Pfam PF17392 Urocanase C-terminal domain 350 544 2.9E-92 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Pfam PF01175 Urocanase Rossmann-like domain 139 347 1.4E-84 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 SUPERFAMILY SSF111326 3 552 1.83E-260 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 Hamap MF_00577 Urocanate hydratase [hutU]. 4 554 49.948 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 ProSitePatterns PS01233 Urocanase signature. 440 455 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 551 3.2E-290 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS13705 810f9af61e0442d53e699bc5bcb33a05 555 PIRSF PIRSF001423 1 554 7.7E-290 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 Pfam PF00512 His Kinase A (phospho-acceptor) domain 126 215 4.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 344 1.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 SUPERFAMILY SSF47384 123 189 1.9E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 SMART SM00388 124 194 7.3E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 SUPERFAMILY SSF55874 188 347 2.62E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 Gene3D G3DSA:3.30.565.10 204 351 4.8E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 SMART SM00387 236 346 1.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 Gene3D G3DSA:1.10.287.130 102 203 8.4E-7 T 28-03-2018 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 277 291 4.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 4.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 305 4.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS11760 8c6fc311fbd4be6fac420b622e0ded06 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 4.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS12715 ce13bd6b969bb25a25f5eec5b5906f76 181 Pfam PF01478 Type IV leader peptidase family 7 110 2.7E-16 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 SmaCSM2_RS17645 f4a941e6068877508f8be80a0d0edd52 242 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 16 224 5.0E-88 T 28-03-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 SmaCSM2_RS17645 f4a941e6068877508f8be80a0d0edd52 242 Pfam PF01618 MotA/TolQ/ExbB proton channel family 108 205 1.1E-32 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS15415 0c396a3bcde68daf9817291adb6a5614 190 SUPERFAMILY SSF51283 3 189 3.79E-51 T 28-03-2018 IPR029054 dUTPase-like SmaCSM2_RS15415 0c396a3bcde68daf9817291adb6a5614 190 Pfam PF00692 dUTPase 79 185 3.2E-7 T 28-03-2018 IPR029054 dUTPase-like SmaCSM2_RS15415 0c396a3bcde68daf9817291adb6a5614 190 Gene3D G3DSA:2.70.40.10 1 161 3.8E-62 T 28-03-2018 SmaCSM2_RS15415 0c396a3bcde68daf9817291adb6a5614 190 Hamap MF_00146 dCTP deaminase [dcd]. 1 190 27.784 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SmaCSM2_RS15415 0c396a3bcde68daf9817291adb6a5614 190 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 5 189 1.2E-46 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 Pfam PF00815 Histidinol dehydrogenase 25 427 2.0E-161 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 SUPERFAMILY SSF53720 5 427 4.83E-79 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 199 224 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 169 195 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 1.1E-92 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 427 40.16 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 Gene3D G3DSA:3.40.50.1980 226 371 1.2E-68 T 28-03-2018 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 PIRSF PIRSF000099 1 430 3.1E-159 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 426 1.3E-158 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SmaCSM2_RS09540 a17d6e106eadbf7c0ec2d286673ac735 431 Gene3D G3DSA:3.40.50.1980 26 225 1.1E-80 T 28-03-2018 SmaCSM2_RS01640 14562e90ca1fd55fabcb0dac71ee697b 216 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 27 212 32.015 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS01640 14562e90ca1fd55fabcb0dac71ee697b 216 PIRSF PIRSF001296 27 215 7.2E-65 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS01640 14562e90ca1fd55fabcb0dac71ee697b 216 Pfam PF02669 K+-transporting ATPase, c chain 31 210 1.1E-62 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS01640 14562e90ca1fd55fabcb0dac71ee697b 216 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 32 211 2.0E-56 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 SUPERFAMILY SSF53706 37 196 6.15E-53 T 28-03-2018 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 104 3.7E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 Gene3D G3DSA:2.20.25.90 37 109 6.4E-19 T 28-03-2018 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 Gene3D G3DSA:3.40.50.740 110 196 8.1E-11 T 28-03-2018 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 Pfam PF00384 Molybdopterin oxidoreductase 108 140 3.2E-5 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS17385 787367a8d94af6aa3437eb9fb8a2c61a 196 SMART SM00926 44 105 4.8E-21 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 Gene3D G3DSA:3.40.190.10 179 266 2.2E-24 T 28-03-2018 SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 Gene3D G3DSA:3.40.190.10 90 178 1.1E-10 T 28-03-2018 SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 SUPERFAMILY SSF53850 86 294 4.34E-42 T 28-03-2018 SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 Gene3D G3DSA:1.10.10.10 3 89 4.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 8.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 Pfam PF03466 LysR substrate binding domain 90 294 8.4E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS18075 225bbf7e8e009addffcc9fb28dd05334 294 SUPERFAMILY SSF46785 5 89 3.35E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06315 e0d5fbf90b3b268ba5c972bed285d470 205 Gene3D G3DSA:1.10.3210.10 14 204 1.7E-42 T 28-03-2018 SmaCSM2_RS06315 e0d5fbf90b3b268ba5c972bed285d470 205 Pfam PF13487 HD domain 87 149 3.3E-17 T 28-03-2018 SmaCSM2_RS06315 e0d5fbf90b3b268ba5c972bed285d470 205 SUPERFAMILY SSF109604 25 198 4.57E-35 T 28-03-2018 SmaCSM2_RS06315 e0d5fbf90b3b268ba5c972bed285d470 205 SMART SM00471 31 168 3.9E-9 T 28-03-2018 IPR003607 HD/PDEase domain SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 SUPERFAMILY SSF51569 3 328 7.33E-144 T 28-03-2018 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 325 2.2E-140 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PIRSF PIRSF001415 1 329 1.7E-150 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 300 319 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 153 172 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 191 210 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 245 261 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 270 285 5.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 Gene3D G3DSA:3.20.20.70 1 329 1.0E-151 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 245 257 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS20815 8c4e17c4200d7cdc1ffe6184a5ce3709 329 SMART SM01004 3 326 1.6E-242 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 Pfam PF14849 YidC periplasmic domain 80 362 1.6E-71 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 233 251 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 84 105 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 434 457 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 177 197 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 267 282 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 518 541 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR00701 60kDa inner membrane protein signature 481 503 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 372 552 1.0E-69 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR01900 YidC translocation/secretion protein signature 507 531 2.3E-19 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR01900 YidC translocation/secretion protein signature 358 374 2.3E-19 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 PRINTS PR01900 YidC translocation/secretion protein signature 487 502 2.3E-19 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 554 22.966 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 Pfam PF02096 60Kd inner membrane protein 373 552 5.0E-59 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SmaCSM2_RS21760 1041e8830db3fb525bc530bb98f2c598 571 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 371 2.6E-78 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal SmaCSM2_RS18280 c52424858026d123e48554c554aa470b 146 Pfam PF00072 Response regulator receiver domain 7 129 1.4E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18280 c52424858026d123e48554c554aa470b 146 Gene3D G3DSA:3.40.50.2300 2 144 4.3E-28 T 28-03-2018 SmaCSM2_RS18280 c52424858026d123e48554c554aa470b 146 SMART SM00448 5 129 2.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS18280 c52424858026d123e48554c554aa470b 146 SUPERFAMILY SSF52172 6 142 8.25E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 Gene3D G3DSA:1.20.1250.20 301 515 6.2E-7 T 28-03-2018 SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 80 104 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 SUPERFAMILY SSF103473 61 217 1.92E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 SUPERFAMILY SSF103473 291 513 1.92E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 Gene3D G3DSA:1.20.1250.20 17 210 1.2E-23 T 28-03-2018 SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 Pfam PF00854 POT family 91 462 3.7E-71 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS14315 e5c599e9d5932afc935fef2d721bb9f6 521 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 15 484 9.6E-47 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SmaCSM2_RS03020 c4aaea13ad2740d903001f1a7df6f0d8 279 Pfam PF00535 Glycosyl transferase family 2 7 178 1.1E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS03020 c4aaea13ad2740d903001f1a7df6f0d8 279 SUPERFAMILY SSF53448 5 254 7.5E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS03020 c4aaea13ad2740d903001f1a7df6f0d8 279 Gene3D G3DSA:3.90.550.10 2 253 5.7E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.1E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.3E-37 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 Gene3D G3DSA:2.40.50.140 1 72 1.9E-37 T 28-03-2018 SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.52 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 SUPERFAMILY SSF50249 1 70 1.59E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS10415 4fb6e26fe30f0a19847d6a1778ba0807 72 SMART SM00316 4 72 1.6E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS12750 b976a9017cc355bb1977768c78579a9f 311 Pfam PF00482 Type II secretion system (T2SS), protein F 166 293 3.5E-14 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS01825 de88962e37b3a85d5c54692a39876639 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 62 84 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site SmaCSM2_RS01825 de88962e37b3a85d5c54692a39876639 297 Pfam PF01040 UbiA prenyltransferase family 21 266 3.6E-60 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SmaCSM2_RS01825 de88962e37b3a85d5c54692a39876639 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 7 291 1.1E-90 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SmaCSM2_RS01825 de88962e37b3a85d5c54692a39876639 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 4 292 19.435 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SmaCSM2_RS05075 14703736c78f2cd68c32c685aa9ec714 130 Gene3D G3DSA:3.40.50.510 2 128 1.7E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SmaCSM2_RS05075 14703736c78f2cd68c32c685aa9ec714 130 SUPERFAMILY SSF53062 4 124 3.27E-23 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SmaCSM2_RS05075 14703736c78f2cd68c32c685aa9ec714 130 Pfam PF03610 PTS system fructose IIA component 4 103 7.8E-12 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 83 93 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 54 185 1.3E-36 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 174 185 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 SUPERFAMILY SSF49329 46 185 3.4E-38 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 Gene3D G3DSA:2.60.40.200 39 189 1.6E-37 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 120 129 3.4E-7 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 83 105 3.4E-7 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS00670 4c7a2304150a0b4271eef2a9ae7d2a63 189 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 160 186 3.4E-7 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 Gene3D G3DSA:3.40.30.10 4 106 6.3E-28 T 28-03-2018 SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 11 221 2.5E-91 T 28-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 Gene3D G3DSA:1.20.1050.10 107 222 2.4E-27 T 28-03-2018 SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 SUPERFAMILY SSF52833 9 113 1.57E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 11 88 2.1E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS02625 bde5cea665f96f0e1484a40f6aae1be6 222 SUPERFAMILY SSF47616 90 220 5.4E-33 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS05685 6b4ed6349087ef3ba945b23fd1db488c 213 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 7 199 1.3E-52 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 SmaCSM2_RS05685 6b4ed6349087ef3ba945b23fd1db488c 213 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 7 200 8.6E-55 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 Pfam PF00999 Sodium/hydrogen exchanger family 16 379 5.6E-67 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 Gene3D G3DSA:3.40.50.720 404 565 6.5E-17 T 28-03-2018 SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 SUPERFAMILY SSF51735 406 534 3.79E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 18 290 2.0E-78 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 Gene3D G3DSA:1.20.91.10 234 316 1.8E-11 T 28-03-2018 SmaCSM2_RS09080 f1d4cc7afc4c3cbe68bec0f24d6d775e 610 Pfam PF02254 TrkA-N domain 407 520 6.3E-18 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Gene3D G3DSA:3.40.50.1460 454 712 2.3E-42 T 28-03-2018 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Gene3D G3DSA:1.25.40.10 855 889 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Pfam PF01522 Polysaccharide deacetylase 248 379 1.7E-25 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Pfam PF13181 Tetratricopeptide repeat 846 876 3.5E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Pfam PF13432 Tetratricopeptide repeat 782 842 7.0E-10 T 28-03-2018 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 ProSitePatterns PS00018 EF-hand calcium-binding domain. 667 679 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SUPERFAMILY SSF48452 773 887 1.33E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Gene3D G3DSA:3.20.20.370 230 443 6.6E-46 T 28-03-2018 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Pfam PF00656 Caspase domain 472 667 3.2E-22 T 28-03-2018 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SMART SM00028 810 843 0.0034 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SMART SM00028 844 877 0.026 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SMART SM00028 776 809 0.011 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Gene3D G3DSA:1.25.40.10 819 854 1.6E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 Gene3D G3DSA:1.25.40.10 773 818 1.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SUPERFAMILY SSF88713 232 442 8.34E-51 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS21755 ed405880a0e07d8eebc8941b64580baa 890 SUPERFAMILY SSF52129 466 664 9.52E-16 T 28-03-2018 IPR029030 Caspase-like domain SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 Pfam PF13519 von Willebrand factor type A domain 102 208 1.1E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 Gene3D G3DSA:3.40.50.410 92 282 1.7E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 Gene3D G3DSA:1.25.40.10 368 564 4.5E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 SUPERFAMILY SSF48452 371 445 1.43E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 Pfam PF00515 Tetratricopeptide repeat 398 427 6.6E-9 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 SMART SM00327 99 288 1.8E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 SMART SM00028 396 429 8.2E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS17245 581c68cbaed5b31e848ce257c50fc458 612 SUPERFAMILY SSF53300 100 277 1.59E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 Gene3D G3DSA:3.40.50.150 89 284 7.6E-42 T 28-03-2018 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 SMART SM00138 23 284 7.0E-89 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PIRSF PIRSF000410 10 286 2.6E-89 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 83 95 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 45 58 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 224 238 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 118 138 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 243 266 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 PRINTS PR00996 Glutamate methyltransferase family signature 152 168 7.6E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 SUPERFAMILY SSF53335 90 281 1.28E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 SUPERFAMILY SSF47757 14 89 1.96E-21 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 Pfam PF03705 CheR methyltransferase, all-alpha domain 25 74 7.7E-18 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 Gene3D G3DSA:1.10.155.10 16 88 1.8E-24 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SmaCSM2_RS09995 f074fa74957a7805dd0b62162806368b 289 Pfam PF01739 CheR methyltransferase, SAM binding domain 90 274 7.3E-51 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Gene3D G3DSA:1.25.40.10 313 383 5.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Gene3D G3DSA:1.25.40.10 188 234 1.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Gene3D G3DSA:1.25.40.10 235 270 5.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Pfam PF01841 Transglutaminase-like superfamily 67 131 8.9E-7 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SUPERFAMILY SSF48452 191 357 2.66E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SUPERFAMILY SSF54001 68 175 1.54E-7 T 28-03-2018 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Gene3D G3DSA:1.25.40.10 271 312 1.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Pfam PF13181 Tetratricopeptide repeat 226 255 0.054 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 Pfam PF13181 Tetratricopeptide repeat 296 322 0.025 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SMART SM00028 191 224 3.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SMART SM00028 293 326 0.037 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SMART SM00028 327 360 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15750 98df886735c05f05154ca316fb6ec30c 383 SMART SM00028 225 258 1.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 SUPERFAMILY SSF53067 234 294 6.74E-27 T 28-03-2018 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 SUPERFAMILY SSF53067 332 450 6.74E-27 T 28-03-2018 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 Pfam PF00012 Hsp70 protein 149 254 2.0E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 SUPERFAMILY SSF53067 111 228 2.75E-22 T 28-03-2018 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 SUPERFAMILY SSF53067 1 41 2.75E-22 T 28-03-2018 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 Gene3D G3DSA:3.30.420.40 240 433 2.2E-21 T 28-03-2018 SmaCSM2_RS15760 adc7a2d1f6570d18dc80e730fd1d7118 453 Gene3D G3DSA:3.30.420.40 2 239 7.5E-32 T 28-03-2018 SmaCSM2_RS12075 b5b1bff8160d9bbca77308bb34a4213d 132 Gene3D G3DSA:3.30.300.20 2 130 2.3E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS12075 b5b1bff8160d9bbca77308bb34a4213d 132 SUPERFAMILY SSF82784 5 126 1.44E-31 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS12075 b5b1bff8160d9bbca77308bb34a4213d 132 Pfam PF02566 OsmC-like protein 34 126 4.5E-16 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS10810 3195ca6271f0c6a9bb95ba359517087a 504 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 314 2.0E-52 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS10810 3195ca6271f0c6a9bb95ba359517087a 504 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 211 389 3.0E-39 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS10810 3195ca6271f0c6a9bb95ba359517087a 504 Gene3D G3DSA:2.40.50.100 122 241 5.0E-14 T 28-03-2018 SmaCSM2_RS10810 3195ca6271f0c6a9bb95ba359517087a 504 SUPERFAMILY SSF111369 131 319 1.44E-12 T 28-03-2018 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Pfam PF09106 Elongation factor SelB, winged helix 448 504 6.6E-15 T 28-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 632 1.5E-124 T 28-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF52540 2 204 1.39E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF50465 279 372 2.45E-15 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:1.10.10.10 513 572 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Pfam PF03144 Elongation factor Tu domain 2 203 269 4.2E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 PRINTS PR00315 GTP-binding elongation factor signature 2 15 7.5E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 PRINTS PR00315 GTP-binding elongation factor signature 76 87 7.5E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 PRINTS PR00315 GTP-binding elongation factor signature 60 70 7.5E-6 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:2.40.30.10 279 357 1.7E-10 T 28-03-2018 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Pfam PF09107 Elongation factor SelB, winged helix 586 631 5.8E-18 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF50447 188 272 7.73E-20 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:2.40.30.10 186 272 1.7E-22 T 28-03-2018 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Pfam PF00009 Elongation factor Tu GTP binding domain 2 140 3.8E-28 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:1.10.10.10 575 633 5.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF46785 513 573 2.67E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:1.10.10.10 440 504 1.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 Gene3D G3DSA:3.40.50.300 1 174 3.4E-27 T 28-03-2018 SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF46785 439 508 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17415 a4cdbc2f9c6b16469beb57da558933ca 643 SUPERFAMILY SSF46785 579 633 3.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09020 23ded8dbde9c7ccdfcbcbbd59486e16e 292 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 267 2.7E-108 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 SmaCSM2_RS09020 23ded8dbde9c7ccdfcbcbbd59486e16e 292 SUPERFAMILY SSF53448 5 276 2.7E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS09020 23ded8dbde9c7ccdfcbcbbd59486e16e 292 Pfam PF00483 Nucleotidyl transferase 12 268 2.1E-30 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SmaCSM2_RS09020 23ded8dbde9c7ccdfcbcbbd59486e16e 292 Gene3D G3DSA:3.90.550.10 1 279 5.3E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS11655 65deaa5c6a1c874db5ade3bf12184a93 189 SUPERFAMILY SSF50882 94 183 1.8E-16 T 28-03-2018 IPR016085 Protease inhibitor, beta-barrel domain GO:0004866 SmaCSM2_RS11655 65deaa5c6a1c874db5ade3bf12184a93 189 Pfam PF02974 Protease inhibitor Inh 94 185 4.3E-14 T 28-03-2018 IPR021140 Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 SmaCSM2_RS11655 65deaa5c6a1c874db5ade3bf12184a93 189 Gene3D G3DSA:2.40.128.10 94 185 2.1E-17 T 28-03-2018 SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 Gene3D G3DSA:3.40.30.10 6 110 4.8E-28 T 28-03-2018 SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 SUPERFAMILY SSF52821 201 303 3.54E-21 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 Pfam PF00462 Glutaredoxin 20 84 4.2E-19 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 SMART SM00450 208 303 1.1E-13 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 Pfam PF00581 Rhodanese-like domain 212 300 5.3E-9 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 Gene3D G3DSA:3.40.250.10 204 304 3.6E-19 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 SUPERFAMILY SSF89360 114 201 5.1E-11 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 Gene3D G3DSA:2.60.300.12 111 203 1.9E-10 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 9 103 1.6E-40 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related SmaCSM2_RS17955 eb53dddc163647cda7d5d1ea6d6d1821 308 SUPERFAMILY SSF52833 8 104 4.9E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS01080 7b085c0570474e9ff78b23321f332cd6 239 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 36 146 2.5E-16 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 SmaCSM2_RS01080 7b085c0570474e9ff78b23321f332cd6 239 Gene3D G3DSA:2.60.40.10 148 233 8.1E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS01080 7b085c0570474e9ff78b23321f332cd6 239 SUPERFAMILY SSF49354 32 145 1.96E-16 T 28-03-2018 IPR008962 PapD-like SmaCSM2_RS01080 7b085c0570474e9ff78b23321f332cd6 239 SUPERFAMILY SSF49584 152 231 7.19E-5 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal SmaCSM2_RS01080 7b085c0570474e9ff78b23321f332cd6 239 Gene3D G3DSA:2.60.40.10 34 147 2.7E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 Gene3D G3DSA:3.90.1150.10 286 396 2.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 SUPERFAMILY SSF53383 8 391 7.58E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 Gene3D G3DSA:3.40.640.10 27 285 2.8E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 6 388 47.234 T 28-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 Pfam PF00155 Aminotransferase class I and II 45 384 1.5E-49 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS20650 df2dd36e245f44639531cdef0b516b01 407 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 23 384 2.9E-137 T 28-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 SmaCSM2_RS19750 3de94699a4fcb41de49a6bf6d87d0c9b 130 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 109 3.0E-23 T 28-03-2018 SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 SUPERFAMILY SSF53474 29 182 1.14E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 Gene3D G3DSA:3.40.50.1820 223 431 9.6E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 Gene3D G3DSA:3.40.50.1820 29 205 1.3E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 PIRSF PIRSF029063 1 438 9.9E-144 T 28-03-2018 IPR011225 Type IV secretory pathway, VirJ component SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 SUPERFAMILY SSF53474 240 434 1.11E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS15730 ca0739a08af9ccd47e470ed9144cdcb6 439 Pfam PF06057 Bacterial virulence protein (VirJ) 252 436 2.8E-77 T 28-03-2018 IPR010333 Bacterial virulence SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Gene3D G3DSA:2.30.42.10 517 620 3.7E-13 T 28-03-2018 SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Gene3D G3DSA:2.40.70.10 398 516 9.5E-11 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Gene3D G3DSA:2.40.70.10 262 387 1.0E-14 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Pfam PF13650 Aspartyl protease 269 361 5.7E-13 T 28-03-2018 SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 SUPERFAMILY SSF50630 263 338 1.99E-8 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Gene3D G3DSA:2.50.20.10 43 245 1.8E-4 T 28-03-2018 SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 Pfam PF13180 PDZ domain 538 612 5.5E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS20520 c3f717ed30c4b7581320644e93970ba6 625 SUPERFAMILY SSF50156 530 616 2.23E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 SUPERFAMILY SSF118352 227 283 3.27E-17 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 Gene3D G3DSA:3.55.30.10 1 178 1.8E-50 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 Gene3D G3DSA:3.90.1280.10 228 283 1.0E-19 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 PIRSF PIRSF005261 1 287 9.2E-88 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 Gene3D G3DSA:1.10.287.480 183 227 7.5E-16 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 Pfam PF01430 Hsp33 protein 6 274 1.0E-78 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS16355 6d08bc0c0423206b291f54864ce4cae0 297 SUPERFAMILY SSF64397 5 234 2.88E-58 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 910 927 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 171 8.0E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 Pfam PF00593 TonB dependent receptor 462 926 9.3E-27 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 Gene3D G3DSA:2.40.170.20 175 927 2.0E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 Gene3D G3DSA:2.170.130.10 43 174 9.6E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 SUPERFAMILY SSF56935 541 722 4.71E-78 T 28-03-2018 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 SUPERFAMILY SSF56935 281 501 4.71E-78 T 28-03-2018 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 SUPERFAMILY SSF56935 44 244 4.71E-78 T 28-03-2018 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 SUPERFAMILY SSF56935 749 927 4.71E-78 T 28-03-2018 SmaCSM2_RS05410 afb7a02a9222fd75fbe65bd4103856cf 927 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 50 927 2.6E-216 T 28-03-2018 IPR010104 Bacterial TonB-dependent receptor SmaCSM2_RS20840 33c8a26019801339918aae16c9b4b76a 171 Pfam PF08695 Cytochrome oxidase complex assembly protein 1 34 143 1.3E-8 T 28-03-2018 IPR014807 Cytochrome oxidase assembly protein 1 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 2 452 55.508 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 SUPERFAMILY SSF53623 100 311 4.71E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Gene3D G3DSA:3.40.1190.10 92 315 2.2E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 SUPERFAMILY SSF51984 2 90 1.03E-16 T 28-03-2018 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Gene3D G3DSA:3.40.50.720 2 91 4.1E-8 T 28-03-2018 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Pfam PF01225 Mur ligase family, catalytic domain 4 98 2.5E-12 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 SUPERFAMILY SSF53244 314 450 5.23E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 4 452 7.5E-185 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Gene3D G3DSA:3.90.190.20 316 453 2.9E-27 T 28-03-2018 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Pfam PF08245 Mur ligase middle domain 109 294 4.4E-24 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SmaCSM2_RS17600 a85a685fb2e9fd75cb7677021999a36d 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 379 4.8E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Pfam PF13360 PQQ-like domain 719 818 7.5E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Pfam PF13360 PQQ-like domain 403 549 1.4E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SUPERFAMILY SSF50998 310 562 7.59E-143 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SUPERFAMILY SSF50998 180 277 7.59E-143 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SUPERFAMILY SSF50998 692 841 7.59E-143 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SUPERFAMILY SSF50998 599 665 7.59E-143 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SMART SM00564 764 797 8.7E-4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SMART SM00564 380 421 9.5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SMART SM00564 696 736 270.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SMART SM00564 235 266 0.0029 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 SMART SM00564 522 553 36.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Gene3D G3DSA:2.140.10.10 160 655 1.9E-83 T 28-03-2018 SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Gene3D G3DSA:2.140.10.10 692 765 0.0018 T 28-03-2018 SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Gene3D G3DSA:2.140.10.10 766 837 2.9E-10 T 28-03-2018 SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 Pfam PF01011 PQQ enzyme repeat 240 274 2.5E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SmaCSM2_RS13840 8eeff95fdb7f6d279c85626822193a90 842 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 22 841 7.1E-296 T 28-03-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 SmaCSM2_RS17285 957fca90e50de487f3d556184ea0cc59 297 Pfam PF05137 Fimbrial assembly protein (PilN) 100 189 9.0E-27 T 28-03-2018 IPR007813 Fimbrial assembly PilN SmaCSM2_RS14335 e6327253d7b2b9c80c32d16c51698bde 137 Gene3D G3DSA:3.30.370.10 38 129 1.4E-20 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SmaCSM2_RS14335 e6327253d7b2b9c80c32d16c51698bde 137 SUPERFAMILY SSF52038 40 130 3.92E-21 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SmaCSM2_RS14335 e6327253d7b2b9c80c32d16c51698bde 137 Pfam PF01337 Barstar (barnase inhibitor) 42 123 2.6E-22 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SmaCSM2_RS12525 07a269b2b29bf8f30807493c7217f8fc 311 Pfam PF00296 Luciferase-like monooxygenase 28 232 5.9E-38 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS12525 07a269b2b29bf8f30807493c7217f8fc 311 Gene3D G3DSA:3.20.20.30 2 311 1.8E-49 T 28-03-2018 SmaCSM2_RS12525 07a269b2b29bf8f30807493c7217f8fc 311 SUPERFAMILY SSF51679 26 309 2.36E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS12525 07a269b2b29bf8f30807493c7217f8fc 311 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 7 309 1.4E-104 T 28-03-2018 IPR020020 Luciferase-type oxidoreductase SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.2E-40 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.2E-40 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.2E-40 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.2E-40 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.2E-40 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.161 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 Pfam PF00334 Nucleoside diphosphate kinase 4 137 2.7E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 SMART SM00562 3 140 4.1E-84 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 SUPERFAMILY SSF54919 1 140 4.71E-56 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 Gene3D G3DSA:3.30.70.141 56 140 1.1E-32 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS09040 505a492dcb9af4f4df68b77008e3d642 141 Gene3D G3DSA:3.30.70.141 1 55 3.1E-16 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SmaCSM2_RS12250 4033aafebb324a6367ccafb880d8d985 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 212 1.6E-74 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 SmaCSM2_RS12250 4033aafebb324a6367ccafb880d8d985 227 SUPERFAMILY SSF161098 5 215 2.09E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS12250 4033aafebb324a6367ccafb880d8d985 227 Gene3D G3DSA:1.10.3720.10 3 224 6.2E-42 T 28-03-2018 SmaCSM2_RS12250 4033aafebb324a6367ccafb880d8d985 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 214 6.9E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 Gene3D G3DSA:1.10.1740.10 15 68 4.9E-9 T 28-03-2018 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 168 1.7E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 SUPERFAMILY SSF88946 18 79 3.22E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 Gene3D G3DSA:1.10.10.10 69 171 9.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 Pfam PF04542 Sigma-70 region 2 20 82 4.9E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 Pfam PF08281 Sigma-70, region 4 120 167 1.8E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS11805 51c459c11e71390540e13c28fdb9113f 174 SUPERFAMILY SSF88659 111 168 2.62E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12600 2d5fbac8f85f7659f087691a91c161a6 346 Pfam PF00268 Ribonucleotide reductase, small chain 31 304 2.0E-68 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS12600 2d5fbac8f85f7659f087691a91c161a6 346 SUPERFAMILY SSF47240 22 346 8.12E-87 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS12600 2d5fbac8f85f7659f087691a91c161a6 346 Gene3D G3DSA:1.10.620.20 9 322 5.9E-72 T 28-03-2018 SmaCSM2_RS12600 2d5fbac8f85f7659f087691a91c161a6 346 PIRSF PIRSF000355 1 346 2.5E-112 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS07795 1616d7d3882fc4f9cd4949d3f4e3a665 291 Pfam PF13614 AAA domain 1 168 1.2E-23 T 28-03-2018 IPR025669 AAA domain SmaCSM2_RS07795 1616d7d3882fc4f9cd4949d3f4e3a665 291 SUPERFAMILY SSF52540 1 267 7.63E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07795 1616d7d3882fc4f9cd4949d3f4e3a665 291 Gene3D G3DSA:3.40.50.300 1 277 1.6E-44 T 28-03-2018 SmaCSM2_RS16530 04869a365bbc4d673778af879e81bcca 317 SUPERFAMILY SSF53448 19 263 1.5E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS16530 04869a365bbc4d673778af879e81bcca 317 Pfam PF13641 Glycosyltransferase like family 2 21 225 1.7E-16 T 28-03-2018 SmaCSM2_RS16530 04869a365bbc4d673778af879e81bcca 317 Gene3D G3DSA:3.90.550.10 8 257 9.7E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 Gene3D G3DSA:1.10.287.90 26 111 3.4E-17 T 28-03-2018 SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 Pfam PF06481 COX Aromatic Rich Motif 236 279 3.9E-15 T 28-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 SUPERFAMILY SSF49503 118 277 7.3E-47 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 Gene3D G3DSA:2.60.40.420 112 277 1.8E-47 T 28-03-2018 IPR008972 Cupredoxin SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 PIRSF PIRSF000292 1 300 9.8E-123 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 SUPERFAMILY SSF81464 26 115 2.29E-20 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20430 fc1612074c5ff048ce522150c57b0271 301 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 14 236 3.0E-104 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 SmaCSM2_RS14765 674c31c117f795b0e84e107b84d466b8 160 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 7 136 7.5E-30 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SmaCSM2_RS14765 674c31c117f795b0e84e107b84d466b8 160 Gene3D G3DSA:3.40.50.300 1 150 5.2E-38 T 28-03-2018 SmaCSM2_RS14765 674c31c117f795b0e84e107b84d466b8 160 SUPERFAMILY SSF52540 25 147 4.76E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14765 674c31c117f795b0e84e107b84d466b8 160 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 128 4.9E-29 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 PRINTS PR01011 Glutathione peroxidase family signature 90 106 2.3E-14 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 PRINTS PR01011 Glutathione peroxidase family signature 55 72 2.3E-14 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 PRINTS PR01011 Glutathione peroxidase family signature 151 160 2.3E-14 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 ProSitePatterns PS00460 Glutathione peroxidases active site. 57 72 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 Pfam PF00255 Glutathione peroxidase 46 143 4.0E-33 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 Gene3D G3DSA:3.40.30.10 37 191 1.2E-34 T 28-03-2018 SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 SUPERFAMILY SSF52833 35 189 4.42E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14060 31fcc8931532bcf349faf12c7ac0aa5e 195 PIRSF PIRSF000303 11 193 4.5E-57 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SmaCSM2_RS03545 cf1ca9817eb4f47236c903df238a04d8 338 SUPERFAMILY SSF56300 1 279 3.28E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS03545 cf1ca9817eb4f47236c903df238a04d8 338 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 259 2.5E-77 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 SmaCSM2_RS03545 cf1ca9817eb4f47236c903df238a04d8 338 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 44.605 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 SmaCSM2_RS03545 cf1ca9817eb4f47236c903df238a04d8 338 Gene3D G3DSA:3.60.21.10 1 275 1.4E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS03545 cf1ca9817eb4f47236c903df238a04d8 338 Pfam PF00149 Calcineurin-like phosphoesterase 1 124 2.5E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 Gene3D G3DSA:1.10.286.20 8 48 1.3E-13 T 28-03-2018 SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 PIRSF PIRSF006092 31 133 9.6E-26 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 Gene3D G3DSA:3.10.50.30 50 134 3.3E-21 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 Pfam PF14760 Rnk N-terminus 9 48 4.0E-14 T 28-03-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 SUPERFAMILY SSF54534 54 129 7.32E-17 T 28-03-2018 SmaCSM2_RS03645 c8576d517bd2ea1bed4fdfbd66340e2a 134 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 55 130 4.3E-21 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SmaCSM2_RS02475 dffd7a2bea715cb5091a72c7a46acbf3 171 Pfam PF07977 FabA-like domain 28 157 3.0E-50 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS02475 dffd7a2bea715cb5091a72c7a46acbf3 171 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 5 170 1.4E-90 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS02475 dffd7a2bea715cb5091a72c7a46acbf3 171 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 1 171 49.467 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS02475 dffd7a2bea715cb5091a72c7a46acbf3 171 SUPERFAMILY SSF54637 5 168 1.15E-55 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS02475 dffd7a2bea715cb5091a72c7a46acbf3 171 Gene3D G3DSA:3.10.129.10 1 171 2.3E-48 T 28-03-2018 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 Gene3D G3DSA:2.30.330.10 15 111 4.4E-29 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 PRINTS PR00956 Flagellar motor switch protein FliN signature 77 92 1.8E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 PRINTS PR00956 Flagellar motor switch protein FliN signature 64 77 1.8E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 PRINTS PR00956 Flagellar motor switch protein FliN signature 31 47 1.8E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 PRINTS PR00956 Flagellar motor switch protein FliN signature 48 64 1.8E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 28 103 5.4E-33 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 32 101 1.9E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS10140 5d18bb6123bcfdc960549754fa904277 111 SUPERFAMILY SSF101801 28 109 8.63E-25 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Pfam PF13844 Glycosyl transferase family 41 204 355 1.9E-25 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Pfam PF13844 Glycosyl transferase family 41 364 555 2.8E-45 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Pfam PF13432 Tetratricopeptide repeat 26 89 1.7E-6 T 28-03-2018 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 SUPERFAMILY SSF53756 268 555 4.21E-7 T 28-03-2018 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Gene3D G3DSA:1.25.40.10 83 148 1.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Gene3D G3DSA:1.25.40.10 5 82 1.7E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 SMART SM00028 55 88 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 SMART SM00028 21 54 9.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 SMART SM00028 89 122 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 Gene3D G3DSA:3.40.50.2000 349 540 9.1E-27 T 28-03-2018 SmaCSM2_RS03800 6ee02e5ea4aaf9accfe7f60d78ed049b 568 SUPERFAMILY SSF48452 8 158 2.07E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS05680 b64d756ff083d9b250aeffea14f238e1 285 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 285 108.644 T 28-03-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SmaCSM2_RS05680 b64d756ff083d9b250aeffea14f238e1 285 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 22 279 1.2E-73 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SmaCSM2_RS05680 b64d756ff083d9b250aeffea14f238e1 285 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 18 282 1.2E-89 T 28-03-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SmaCSM2_RS10585 321f76a2a3fdb1c7c32dd88c35146073 224 Pfam PF12973 ChrR Cupin-like domain 131 200 8.8E-8 T 28-03-2018 IPR025979 ChrR-like cupin domain SmaCSM2_RS10585 321f76a2a3fdb1c7c32dd88c35146073 224 SUPERFAMILY SSF51182 98 208 1.76E-11 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS10585 321f76a2a3fdb1c7c32dd88c35146073 224 Gene3D G3DSA:2.60.120.10 116 206 3.6E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS10585 321f76a2a3fdb1c7c32dd88c35146073 224 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 5 224 6.9E-48 T 28-03-2018 IPR012807 Anti-sigma factor ChrR, putative SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 Gene3D G3DSA:3.40.1280.10 1 155 7.4E-52 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 28.388 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 SUPERFAMILY SSF75217 1 153 7.33E-48 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 155 9.3E-53 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 1.3E-48 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS15605 10801cdc46307f13abb0779724c69bc8 156 PIRSF PIRSF004505 1 155 1.3E-45 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SmaCSM2_RS11290 12d658565984f476696140f0eb39949b 145 SUPERFAMILY SSF46785 34 138 1.46E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11290 12d658565984f476696140f0eb39949b 145 Pfam PF01638 HxlR-like helix-turn-helix 40 126 2.5E-23 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SmaCSM2_RS11290 12d658565984f476696140f0eb39949b 145 Gene3D G3DSA:1.10.10.10 36 138 1.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18125 9f575749ba5a82cce3a5771957ae4f59 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 12 240 1.2E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS18125 9f575749ba5a82cce3a5771957ae4f59 255 SUPERFAMILY SSF56219 4 251 7.59E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS18125 9f575749ba5a82cce3a5771957ae4f59 255 Gene3D G3DSA:3.60.10.10 1 248 8.3E-27 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS05935 6268e571a9736fcdce4221a4e3a9a8a6 627 Gene3D G3DSA:2.30.42.10 534 602 6.6E-6 T 28-03-2018 SmaCSM2_RS05935 6268e571a9736fcdce4221a4e3a9a8a6 627 PIRSF PIRSF016493 30 627 1.1E-134 T 28-03-2018 IPR024191 Peptidase M61 SmaCSM2_RS05935 6268e571a9736fcdce4221a4e3a9a8a6 627 SUPERFAMILY SSF50156 524 597 9.68E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS05935 6268e571a9736fcdce4221a4e3a9a8a6 627 Gene3D G3DSA:1.10.390.10 295 485 3.4E-12 T 28-03-2018 SmaCSM2_RS05935 6268e571a9736fcdce4221a4e3a9a8a6 627 Pfam PF05299 M61 glycyl aminopeptidase 304 421 2.1E-34 T 28-03-2018 IPR007963 Peptidase M61, catalytic domain SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Gene3D G3DSA:3.40.50.720 228 440 8.2E-72 T 28-03-2018 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Gene3D G3DSA:1.20.5.100 205 227 1.7E-14 T 28-03-2018 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 SMART SM00984 324 428 1.2E-50 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 424 1.5E-141 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 427 2.0E-33 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 SUPERFAMILY SSF52413 317 439 5.75E-38 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 PIRSF PIRSF500134 1 446 3.5E-191 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 SUPERFAMILY SSF51735 1 195 8.79E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 2.3E-39 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 8.3E-69 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 Gene3D G3DSA:3.40.50.720 1 201 3.3E-62 T 28-03-2018 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 PIRSF PIRSF000124 1 443 1.4E-152 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SmaCSM2_RS14050 4def33218ca88b22d79b2a23dbad7681 449 SUPERFAMILY SSF48179 204 301 1.84E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SmaCSM2_RS13910 f1368880409d77460d6a96f662134b98 112 SUPERFAMILY SSF89360 1 96 1.1E-25 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS13910 f1368880409d77460d6a96f662134b98 112 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.4E-15 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS13910 f1368880409d77460d6a96f662134b98 112 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 106 3.9E-31 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 SmaCSM2_RS13910 f1368880409d77460d6a96f662134b98 112 Gene3D G3DSA:2.60.300.12 2 110 2.3E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS13910 f1368880409d77460d6a96f662134b98 112 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 SmaCSM2_RS14445 1daaaa85dbfc49ceaf7814aabe7f187c 375 Pfam PF07690 Major Facilitator Superfamily 17 343 1.9E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS14445 1daaaa85dbfc49ceaf7814aabe7f187c 375 SUPERFAMILY SSF103473 3 369 1.27E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS14445 1daaaa85dbfc49ceaf7814aabe7f187c 375 Gene3D G3DSA:1.20.1250.20 194 372 3.5E-7 T 28-03-2018 SmaCSM2_RS14445 1daaaa85dbfc49ceaf7814aabe7f187c 375 Gene3D G3DSA:1.20.1250.20 2 190 1.6E-21 T 28-03-2018 SmaCSM2_RS09105 6871fd8588cb90b80c936cc93b83fd77 333 Pfam PF04471 Restriction endonuclease 195 304 1.8E-15 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SmaCSM2_RS09105 6871fd8588cb90b80c936cc93b83fd77 333 Gene3D G3DSA:3.40.1350.10 186 310 3.1E-11 T 28-03-2018 SmaCSM2_RS09105 6871fd8588cb90b80c936cc93b83fd77 333 SUPERFAMILY SSF52980 196 307 1.61E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 Pfam PF00270 DEAD/DEAH box helicase 36 89 1.0E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 Gene3D G3DSA:3.40.50.300 470 643 6.2E-8 T 28-03-2018 SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 SMART SM00491 495 623 7.1E-39 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 Pfam PF13307 Helicase C-terminal domain 480 636 3.4E-33 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 SUPERFAMILY SSF52540 192 258 3.33E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 SUPERFAMILY SSF52540 582 619 3.33E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 SUPERFAMILY SSF52540 24 115 3.33E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16515 100f10cde61e165febaeb90197fdb93c 682 Gene3D G3DSA:3.40.50.300 24 446 7.2E-27 T 28-03-2018 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 SUPERFAMILY SSF56935 684 826 1.33E-80 T 28-03-2018 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 SUPERFAMILY SSF56935 860 972 1.33E-80 T 28-03-2018 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 SUPERFAMILY SSF56935 157 586 1.33E-80 T 28-03-2018 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 Gene3D G3DSA:2.170.130.10 153 279 1.7E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 Gene3D G3DSA:2.40.170.20 308 971 2.4E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 Pfam PF00593 TonB dependent receptor 421 971 5.7E-43 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 Pfam PF07660 Secretin and TonB N terminus short domain 67 117 9.3E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 SMART SM00965 67 118 2.9E-11 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS17665 e4f6b0a0b0e8011940df8ae77adecdcf 972 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 264 3.8E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 41 7.0E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 41 1.5E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 Gene3D G3DSA:3.30.700.10 21 145 1.6E-18 T 28-03-2018 SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 SUPERFAMILY SSF54523 21 149 2.93E-20 T 28-03-2018 SmaCSM2_RS14915 89a6d90e3bbd80e312d4691a9ed8ca4e 151 Pfam PF00114 Pilin (bacterial filament) 49 150 7.0E-19 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS10625 32b3b22933eeaa87f4048f80b79842f1 159 Pfam PF00583 Acetyltransferase (GNAT) family 48 130 4.7E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS10625 32b3b22933eeaa87f4048f80b79842f1 159 SUPERFAMILY SSF55729 1 159 1.89E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS10625 32b3b22933eeaa87f4048f80b79842f1 159 Gene3D G3DSA:3.40.630.30 1 159 1.6E-24 T 28-03-2018 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 SUPERFAMILY SSF143975 4 418 8.24E-132 T 28-03-2018 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 SUPERFAMILY SSF52016 419 607 2.2E-61 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 606 44.506 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 606 1.0E-245 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 Pfam PF00920 Dehydratase family 34 603 1.2E-217 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SmaCSM2_RS20780 6897d190c06fbae8b62e62f16fce43b9 612 Gene3D G3DSA:3.40.50.2300 89 246 2.6E-6 T 28-03-2018 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 Hamap MF_01377 Probable lipid kinase YegS [yegS]. 5 308 45.274 T 28-03-2018 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 Gene3D G3DSA:3.40.50.10330 4 133 4.5E-26 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 SUPERFAMILY SSF111331 4 305 8.07E-67 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 SMART SM00046 5 130 1.6E-13 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 130 7.4E-27 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 TIGRFAM TIGR03702 lip_kinase_YegS: lipid kinase YegS 6 307 1.8E-129 T 28-03-2018 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 SmaCSM2_RS19715 8a4e9b5586d863f4e9d3f7772e28120a 317 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 8 302 2.8E-57 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:1.10.287.130 799 868 1.1E-18 T 28-03-2018 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF63829 350 430 3.49E-15 T 28-03-2018 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF63829 523 635 3.49E-15 T 28-03-2018 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:2.130.10.10 394 642 9.5E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:2.130.10.10 165 393 9.7E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:2.130.10.10 31 164 7.7E-27 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF07495 Y_Y_Y domain 693 754 1.0E-12 T 28-03-2018 IPR011123 Two component regulator three Y SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SMART SM00448 1058 1168 2.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 921 1034 3.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF47384 798 875 1.71E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF55874 863 1033 9.17E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF52172 1055 1173 9.11E-28 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SMART SM00387 921 1035 9.1E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1019 1032 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 PRINTS PR00344 Bacterial sensor protein C-terminal signature 959 973 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 PRINTS PR00344 Bacterial sensor protein C-terminal signature 995 1013 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 PRINTS PR00344 Bacterial sensor protein C-terminal signature 977 987 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF07494 Two component regulator propeller 78 101 0.0035 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF07494 Two component regulator propeller 37 60 1.7E-4 T 28-03-2018 IPR011110 Two component regulator propeller SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SMART SM00388 809 874 9.2E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:3.40.50.2300 1036 1174 1.5E-29 T 28-03-2018 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 SUPERFAMILY SSF63829 30 234 8.99E-21 T 28-03-2018 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Gene3D G3DSA:3.30.565.10 869 1035 2.2E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF00072 Response regulator receiver domain 1060 1168 1.9E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16265 65243129819e73bc519fbc99f5839f19 1174 Pfam PF00512 His Kinase A (phospho-acceptor) domain 809 874 2.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS13415 006781d1fd0a94dcd7c64bd949194457 327 SUPERFAMILY SSF53955 15 39 3.94E-14 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS13415 006781d1fd0a94dcd7c64bd949194457 327 SUPERFAMILY SSF53955 67 144 3.94E-14 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS13415 006781d1fd0a94dcd7c64bd949194457 327 Pfam PF01464 Transglycosylase SLT domain 16 138 1.5E-11 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS13415 006781d1fd0a94dcd7c64bd949194457 327 Gene3D G3DSA:1.10.530.10 8 281 1.8E-13 T 28-03-2018 SmaCSM2_RS04495 c93430842d58eed4df6ace15447ba5f9 234 Gene3D G3DSA:3.60.40.10 1 232 2.7E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS04495 c93430842d58eed4df6ace15447ba5f9 234 SMART SM00331 8 233 2.7E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS04495 c93430842d58eed4df6ace15447ba5f9 234 SMART SM00332 3 231 2.5E-14 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS04495 c93430842d58eed4df6ace15447ba5f9 234 SUPERFAMILY SSF81606 2 232 2.22E-63 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS04495 c93430842d58eed4df6ace15447ba5f9 234 Pfam PF13672 Protein phosphatase 2C 15 193 4.4E-16 T 28-03-2018 SmaCSM2_RS15320 32881bb7bc11d683f7a29a9fa01d6a0b 216 Gene3D G3DSA:3.40.30.10 46 212 8.1E-23 T 28-03-2018 SmaCSM2_RS15320 32881bb7bc11d683f7a29a9fa01d6a0b 216 SUPERFAMILY SSF52833 47 211 4.78E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS15320 32881bb7bc11d683f7a29a9fa01d6a0b 216 Pfam PF02630 SCO1/SenC 46 190 7.7E-23 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS18530 c16eacf915b7ee09481b629324e49654 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 5 92 1.5E-16 T 28-03-2018 IPR007711 Toxin HigB-1 SmaCSM2_RS18530 c16eacf915b7ee09481b629324e49654 92 Gene3D G3DSA:3.30.2310.20 1 92 1.1E-26 T 28-03-2018 SmaCSM2_RS18530 c16eacf915b7ee09481b629324e49654 92 SUPERFAMILY SSF143011 1 92 3.4E-15 T 28-03-2018 IPR035095 Toxin RelE-like domain SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 145 5.1E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 Gene3D G3DSA:3.40.50.720 179 343 2.2E-16 T 28-03-2018 SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 SUPERFAMILY SSF50129 7 185 5.78E-56 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 SUPERFAMILY SSF51735 163 361 5.76E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 Gene3D G3DSA:3.90.180.10 3 178 7.1E-31 T 28-03-2018 SmaCSM2_RS07425 0648909df18f9e5a1a213097a0ea6c72 404 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 SUPERFAMILY SSF51182 9 283 7.53E-93 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 Pfam PF02678 Pirin 24 124 5.3E-38 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 Gene3D G3DSA:2.60.120.10 4 245 3.5E-87 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 PIRSF PIRSF006232 5 283 3.0E-102 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 Pfam PF05726 Pirin C-terminal cupin domain 179 283 2.8E-31 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SmaCSM2_RS15995 5c6dd17c726a1051e9c6ad116268caff 283 Gene3D G3DSA:2.60.120.10 246 283 4.1E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS09415 b64ab69073db2f2c92baa9c1f9aed8ab 188 SUPERFAMILY SSF48498 84 168 5.82E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS09415 b64ab69073db2f2c92baa9c1f9aed8ab 188 Gene3D G3DSA:1.10.260.40 35 62 9.3E-7 T 28-03-2018 SmaCSM2_RS09415 b64ab69073db2f2c92baa9c1f9aed8ab 188 Gene3D G3DSA:1.10.357.10 63 188 4.4E-8 T 28-03-2018 SmaCSM2_RS09415 b64ab69073db2f2c92baa9c1f9aed8ab 188 Gene3D G3DSA:1.10.10.10 2 34 9.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09415 b64ab69073db2f2c92baa9c1f9aed8ab 188 SUPERFAMILY SSF46689 2 68 2.09E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 Gene3D G3DSA:1.10.10.10 129 213 7.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 Gene3D G3DSA:3.40.50.2300 2 128 2.7E-23 T 28-03-2018 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 SMART SM00421 149 206 2.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 5.7E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 SUPERFAMILY SSF52172 2 133 1.34E-23 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 SMART SM00448 3 120 1.9E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 Pfam PF00072 Response regulator receiver domain 5 120 2.6E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS03860 97f12daadc26efc2692fb63cbaf7c6ce 213 SUPERFAMILY SSF46894 138 211 3.4E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 Gene3D G3DSA:1.10.1660.10 1 55 1.4E-18 T 28-03-2018 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 Pfam PF13411 MerR HTH family regulatory protein 1 65 1.9E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 SMART SM00422 1 69 3.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 SUPERFAMILY SSF46955 1 110 2.64E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS09810 f3c23cae8dd8462d0b40672153e36cbc 131 Gene3D G3DSA:1.10.1660.10 56 125 1.4E-9 T 28-03-2018 SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 SMART SM01011 7 141 3.2E-66 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 Gene3D G3DSA:3.90.230.10 170 440 1.2E-78 T 28-03-2018 SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 SUPERFAMILY SSF55920 180 438 2.62E-80 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 Pfam PF00557 Metallopeptidase family M24 186 417 1.2E-59 T 28-03-2018 IPR000994 Peptidase M24 SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 Gene3D G3DSA:3.40.350.10 5 169 5.4E-52 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 SUPERFAMILY SSF53092 7 179 6.8E-55 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SmaCSM2_RS17470 0f4e8c7ce7371dbfb90fab087b7106d6 440 Pfam PF05195 Aminopeptidase P, N-terminal domain 12 131 5.7E-38 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 Gene3D G3DSA:3.30.70.250 146 184 9.7E-20 T 28-03-2018 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 6 292 5.3E-101 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9 304 1.3E-40 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 Gene3D G3DSA:3.40.366.10 185 312 6.3E-28 T 28-03-2018 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 SUPERFAMILY SSF52151 6 124 1.49E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 SUPERFAMILY SSF52151 192 312 1.49E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 PIRSF PIRSF000446 3 312 2.4E-102 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 SUPERFAMILY SSF55048 132 199 1.7E-16 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 Gene3D G3DSA:3.40.366.10 3 145 9.3E-42 T 28-03-2018 SmaCSM2_RS04795 93fb593055395f7b724f98cd0b0ecf62 314 Pfam PF00698 Acyl transferase domain 8 281 2.8E-37 T 28-03-2018 IPR014043 Acyl transferase SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 SMART SM00418 10 89 5.7E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 SUPERFAMILY SSF46785 9 89 2.72E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 Gene3D G3DSA:1.10.10.10 192 232 0.42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 Gene3D G3DSA:1.10.10.10 4 97 4.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 Gene3D G3DSA:1.10.10.10 113 191 0.22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07830 117620db4c557ff848136423b7b135a5 234 Pfam PF12840 Helix-turn-helix domain 14 69 2.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10830 c2c44ce39d6040a1fe3fc77e4cffd0e4 68 Gene3D G3DSA:3.40.800.10 1 68 3.6E-16 T 28-03-2018 SmaCSM2_RS10830 c2c44ce39d6040a1fe3fc77e4cffd0e4 68 SUPERFAMILY SSF52768 3 66 2.7E-16 T 28-03-2018 SmaCSM2_RS10830 c2c44ce39d6040a1fe3fc77e4cffd0e4 68 Pfam PF00491 Arginase family 3 62 1.9E-13 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS06270 4cf253b071d3680feb3ef4f8ee5a974b 149 SUPERFAMILY SSF46785 4 139 1.01E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06270 4cf253b071d3680feb3ef4f8ee5a974b 149 Gene3D G3DSA:1.10.10.10 1 147 9.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06270 4cf253b071d3680feb3ef4f8ee5a974b 149 Pfam PF01638 HxlR-like helix-turn-helix 15 99 2.0E-18 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 159 177 6.0E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 6.0E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 85 101 6.0E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 ProSitePatterns PS00819 Dps protein family signature 2. 87 101 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 ProSitePatterns PS00818 Dps protein family signature 1. 61 77 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 Pfam PF00210 Ferritin-like domain 43 182 1.7E-27 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 Gene3D G3DSA:1.20.1260.10 9 182 6.4E-49 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 SUPERFAMILY SSF47240 29 182 1.5E-44 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS16555 e7069c85b2b7c915d1738a51a5c51326 182 PIRSF PIRSF005900 20 182 1.3E-45 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SmaCSM2_RS01665 5aad3f06452054daa5b09d3321ad3628 219 SUPERFAMILY SSF53271 3 201 1.11E-46 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS01665 5aad3f06452054daa5b09d3321ad3628 219 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 219 32.266 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS01665 5aad3f06452054daa5b09d3321ad3628 219 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 189 6.6E-57 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS01665 5aad3f06452054daa5b09d3321ad3628 219 Gene3D G3DSA:3.40.50.2020 1 195 1.7E-48 T 28-03-2018 SmaCSM2_RS01665 5aad3f06452054daa5b09d3321ad3628 219 Pfam PF00156 Phosphoribosyl transferase domain 51 159 3.4E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SmaCSM2_RS09720 3dcd493c7af0a6eb5502ddc49cdfd4a2 598 Gene3D G3DSA:3.40.390.10 45 195 4.2E-7 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS09720 3dcd493c7af0a6eb5502ddc49cdfd4a2 598 Pfam PF13387 Domain of unknown function (DUF4105) 225 378 2.7E-29 T 28-03-2018 IPR025178 Domain of unknown function DUF4105 SmaCSM2_RS20115 cacf418e9c0e1482a2e6efe5635bbc6c 659 ProSitePatterns PS01303 BCCT family of transporters signature. 319 328 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20115 cacf418e9c0e1482a2e6efe5635bbc6c 659 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 19 500 4.7E-197 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS20115 cacf418e9c0e1482a2e6efe5635bbc6c 659 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 57 501 6.3E-167 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 Pfam PF02954 Bacterial regulatory protein, Fis family 146 179 9.1E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 Gene3D G3DSA:1.10.10.60 133 179 2.3E-13 T 28-03-2018 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 Pfam PF00072 Response regulator receiver domain 10 116 6.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 SMART SM00448 7 118 5.2E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 146 163 3.5E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 163 183 3.5E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 SUPERFAMILY SSF46689 90 179 1.54E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 Gene3D G3DSA:3.40.50.2300 2 120 2.2E-26 T 28-03-2018 SmaCSM2_RS08370 828b3b404ef12325881641b7849932d4 189 SUPERFAMILY SSF52172 10 119 6.83E-28 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS08765 fd3d92879f0aef36e8d323c674ced9c8 399 SUPERFAMILY SSF103473 7 395 3.92E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS08765 fd3d92879f0aef36e8d323c674ced9c8 399 Pfam PF00083 Sugar (and other) transporter 258 391 5.6E-6 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS08765 fd3d92879f0aef36e8d323c674ced9c8 399 Gene3D G3DSA:1.20.1250.20 217 399 2.7E-25 T 28-03-2018 SmaCSM2_RS08765 fd3d92879f0aef36e8d323c674ced9c8 399 Pfam PF07690 Major Facilitator Superfamily 24 252 5.0E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS08765 fd3d92879f0aef36e8d323c674ced9c8 399 Gene3D G3DSA:1.20.1250.20 5 216 2.5E-19 T 28-03-2018 SmaCSM2_RS10300 846ee1b40546bd0794a6254f1870badf 131 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 8 128 1.0E-27 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 SmaCSM2_RS10300 846ee1b40546bd0794a6254f1870badf 131 Pfam PF00460 Flagella basal body rod protein 11 39 2.3E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS10300 846ee1b40546bd0794a6254f1870badf 131 PIRSF PIRSF002889 2 131 2.1E-34 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 SmaCSM2_RS00560 5dc0eb913605022f23bd4d3a80e65d1c 209 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 172 4.7E-18 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SmaCSM2_RS00560 5dc0eb913605022f23bd4d3a80e65d1c 209 Gene3D G3DSA:3.40.50.300 1 202 7.1E-36 T 28-03-2018 SmaCSM2_RS00560 5dc0eb913605022f23bd4d3a80e65d1c 209 SUPERFAMILY SSF52540 1 207 7.19E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05095 b81f62cbbb5ca0ed09b5d6efd42e4de4 105 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 4.7E-24 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SmaCSM2_RS05095 b81f62cbbb5ca0ed09b5d6efd42e4de4 105 SUPERFAMILY SSF69754 1 96 1.57E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SmaCSM2_RS05095 b81f62cbbb5ca0ed09b5d6efd42e4de4 105 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 6.6E-28 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SmaCSM2_RS05095 b81f62cbbb5ca0ed09b5d6efd42e4de4 105 Gene3D G3DSA:3.30.160.100 1 96 1.2E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SmaCSM2_RS05390 fab2aa10043d3c59b8ed4a936bef72eb 195 SUPERFAMILY SSF160631 22 75 6.28E-9 T 28-03-2018 SmaCSM2_RS05390 fab2aa10043d3c59b8ed4a936bef72eb 195 SUPERFAMILY SSF160631 127 189 6.28E-9 T 28-03-2018 SmaCSM2_RS05390 fab2aa10043d3c59b8ed4a936bef72eb 195 Gene3D G3DSA:3.40.1580.10 14 192 1.3E-18 T 28-03-2018 SmaCSM2_RS05390 fab2aa10043d3c59b8ed4a936bef72eb 195 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 28 181 2.0E-11 T 28-03-2018 IPR018958 Knr4/Smi1-like domain SmaCSM2_RS05390 fab2aa10043d3c59b8ed4a936bef72eb 195 SMART SM00860 28 182 0.0077 T 28-03-2018 IPR018958 Knr4/Smi1-like domain SmaCSM2_RS16470 5e82154d3e3b929c985719acb053700e 445 Pfam PF01339 CheB methylesterase 270 421 1.3E-12 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS16470 5e82154d3e3b929c985719acb053700e 445 Gene3D G3DSA:3.40.50.180 258 441 1.6E-14 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS16470 5e82154d3e3b929c985719acb053700e 445 SUPERFAMILY SSF52738 270 437 6.02E-20 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 Gene3D G3DSA:3.40.190.10 31 369 4.1E-55 T 28-03-2018 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 181 200 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 218 237 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 126 142 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 158 172 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 268 287 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 313 339 1.9E-57 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 SUPERFAMILY SSF53850 29 368 3.02E-102 T 28-03-2018 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 PIRSF PIRSF019574 1 369 4.9E-136 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SmaCSM2_RS07040 853a618c9a1c3cb83bd7df7d7cb13033 369 Pfam PF13416 Bacterial extracellular solute-binding protein 46 332 6.4E-36 T 28-03-2018 SmaCSM2_RS12320 1a8cc57ecb84e390d9a1f38ade4a25fb 86 SUPERFAMILY SSF54285 3 86 8.04E-11 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SmaCSM2_RS12320 1a8cc57ecb84e390d9a1f38ade4a25fb 86 Pfam PF02597 ThiS family 7 86 1.8E-7 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SmaCSM2_RS12320 1a8cc57ecb84e390d9a1f38ade4a25fb 86 Gene3D G3DSA:3.10.20.30 2 86 9.6E-16 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 Pfam PF01202 Shikimate kinase 13 166 7.4E-47 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 27.723 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 SUPERFAMILY SSF52540 5 165 2.5E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 PRINTS PR01100 Shikimate kinase family signature 77 86 3.9E-21 T 28-03-2018 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 PRINTS PR01100 Shikimate kinase family signature 59 67 3.9E-21 T 28-03-2018 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 PRINTS PR01100 Shikimate kinase family signature 31 44 3.9E-21 T 28-03-2018 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 PRINTS PR01100 Shikimate kinase family signature 98 115 3.9E-21 T 28-03-2018 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 PRINTS PR01100 Shikimate kinase family signature 7 22 3.9E-21 T 28-03-2018 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SmaCSM2_RS16240 d045447ffd23a384506aa7778bfef554 180 Gene3D G3DSA:3.40.50.300 4 180 8.5E-34 T 28-03-2018 SmaCSM2_RS05310 ee68f82f8d31f38d30b444d2f8b9b979 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 167 390 9.8E-62 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SmaCSM2_RS05310 ee68f82f8d31f38d30b444d2f8b9b979 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 131 402 4.6E-82 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SmaCSM2_RS05310 ee68f82f8d31f38d30b444d2f8b9b979 420 SUPERFAMILY SSF101960 15 412 4.45E-93 T 28-03-2018 SmaCSM2_RS13345 3403b81df93c71895aa1079df054faa8 168 SUPERFAMILY SSF55729 4 146 6.25E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS13345 3403b81df93c71895aa1079df054faa8 168 Pfam PF13527 Acetyltransferase (GNAT) domain 5 129 8.9E-13 T 28-03-2018 SmaCSM2_RS13345 3403b81df93c71895aa1079df054faa8 168 Gene3D G3DSA:3.40.630.30 1 152 1.3E-25 T 28-03-2018 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Gene3D G3DSA:3.40.50.970 1 184 5.6E-38 T 28-03-2018 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 SUPERFAMILY SSF52518 2 181 7.17E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 524 1.9E-34 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 SUPERFAMILY SSF52467 180 346 6.99E-43 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 317 2.4E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 SUPERFAMILY SSF52518 356 557 4.42E-53 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 4.4E-38 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Gene3D G3DSA:3.40.50.970 331 542 1.3E-34 T 28-03-2018 SmaCSM2_RS16830 032c6a4b54a4518d600c1808d0e6b58a 572 Gene3D G3DSA:3.40.50.1220 185 330 6.2E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS02710 366cc67223ddb23fab76949ccc5f1bae 272 Pfam PF01061 ABC-2 type transporter 22 232 8.6E-30 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SmaCSM2_RS02710 366cc67223ddb23fab76949ccc5f1bae 272 PIRSF PIRSF006648 2 267 2.8E-15 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 58 469 7.7E-130 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Gene3D G3DSA:2.30.42.10 287 388 2.3E-24 T 28-03-2018 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 236 253 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 139 159 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 179 203 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 214 231 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 325 337 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 PRINTS PR00834 HtrA/DegQ protease family signature 118 130 8.0E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 SUPERFAMILY SSF50156 402 468 5.26E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Gene3D G3DSA:2.30.42.10 391 476 1.4E-8 T 28-03-2018 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 SUPERFAMILY SSF50156 267 375 1.58E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Gene3D G3DSA:2.40.10.10 180 286 8.1E-38 T 28-03-2018 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 SMART SM00228 285 367 8.8E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 SMART SM00228 391 467 0.41 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 SUPERFAMILY SSF50494 57 282 3.29E-63 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Pfam PF13365 Trypsin-like peptidase domain 108 243 2.1E-32 T 28-03-2018 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Gene3D G3DSA:2.40.10.10 54 179 4.8E-34 T 28-03-2018 SmaCSM2_RS01525 f0e2ce882832a286343badc0e9e337ec 477 Pfam PF13180 PDZ domain 286 375 2.4E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS05715 f9c28c59ab00e1f0f095869ab0e4874f 566 SUPERFAMILY SSF51905 29 367 4.14E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS05715 f9c28c59ab00e1f0f095869ab0e4874f 566 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 41 526 4.2E-223 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 SmaCSM2_RS05715 f9c28c59ab00e1f0f095869ab0e4874f 566 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 37 526 52.216 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 SmaCSM2_RS05715 f9c28c59ab00e1f0f095869ab0e4874f 566 Gene3D G3DSA:3.50.50.60 30 552 6.7E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS05715 f9c28c59ab00e1f0f095869ab0e4874f 566 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 41 524 1.3E-198 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 SmaCSM2_RS13075 6ddcacc5ba132993cc4260fb9ee9b7c5 450 PIRSF PIRSF006060 1 448 1.2E-63 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS13075 6ddcacc5ba132993cc4260fb9ee9b7c5 450 Pfam PF13520 Amino acid permease 7 402 9.1E-49 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS00920 7065291f7b0444d5385030ddd54a8ab0 201 SUPERFAMILY SSF51161 20 189 3.12E-30 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS00920 7065291f7b0444d5385030ddd54a8ab0 201 Gene3D G3DSA:2.160.10.10 3 189 1.0E-33 T 28-03-2018 SmaCSM2_RS00920 7065291f7b0444d5385030ddd54a8ab0 201 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 104 1.4E-6 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 Pfam PF04542 Sigma-70 region 2 21 81 2.9E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 Gene3D G3DSA:1.10.10.10 75 174 1.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 SUPERFAMILY SSF88946 11 93 1.02E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 173 7.3E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 Gene3D G3DSA:1.10.1740.10 6 74 6.4E-16 T 28-03-2018 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 SUPERFAMILY SSF88659 110 172 4.3E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 Pfam PF08281 Sigma-70, region 4 119 170 6.7E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS02275 4fcf60b257d0400ede805e9f1bef4262 420 Gene3D G3DSA:1.25.40.10 216 414 8.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09185 7429f278564ad2ca18ead102cd7be3f6 139 Gene3D G3DSA:1.10.10.10 5 61 2.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09185 7429f278564ad2ca18ead102cd7be3f6 139 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 49 2.4E-13 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SmaCSM2_RS09185 7429f278564ad2ca18ead102cd7be3f6 139 Pfam PF12728 Helix-turn-helix domain 5 50 1.8E-12 T 28-03-2018 SmaCSM2_RS01190 c0d329e707d2271874442aee05401342 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 264 1.2E-50 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS01190 c0d329e707d2271874442aee05401342 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SmaCSM2_RS01190 c0d329e707d2271874442aee05401342 265 Gene3D G3DSA:1.10.12.10 223 265 3.1E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal SmaCSM2_RS01190 c0d329e707d2271874442aee05401342 265 SUPERFAMILY SSF52096 12 264 1.02E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01190 c0d329e707d2271874442aee05401342 265 Gene3D G3DSA:3.90.226.10 11 222 4.6E-60 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 Pfam PF00361 Proton-conducting membrane transporter 139 432 5.3E-88 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 90 110 2.6E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 520 541 2.6E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 658 684 2.6E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 385 407 2.6E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 64 88 2.6E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 Gene3D G3DSA:3.40.50.1980 284 520 3.5E-5 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 9 716 6.1E-233 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 88 113 1.8E-45 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 342 354 1.8E-45 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 274 300 1.8E-45 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 273 1.8E-45 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 451 470 1.8E-45 T 28-03-2018 SmaCSM2_RS15120 20194d0b4e0f94ce83a6f711fc8f7882 721 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 127 1.4E-24 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 Gene3D G3DSA:3.40.190.10 26 190 3.3E-34 T 28-03-2018 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 SUPERFAMILY SSF53850 26 335 6.21E-101 T 28-03-2018 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 Gene3D G3DSA:3.40.190.10 192 338 9.2E-25 T 28-03-2018 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 334 6.9E-131 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 PIRSF PIRSF002756 3 337 4.4E-109 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SmaCSM2_RS06900 c43e864fb938b03d41dfb48bb5e773df 338 Pfam PF12849 PBP superfamily domain 22 307 1.7E-63 T 28-03-2018 IPR024370 PBP domain SmaCSM2_RS05515 3c5abdb2de82653d23339907cde55eca 350 SUPERFAMILY SSF51658 9 323 4.84E-61 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05515 3c5abdb2de82653d23339907cde55eca 350 Gene3D G3DSA:3.20.20.150 12 348 8.9E-49 T 28-03-2018 SmaCSM2_RS05515 3c5abdb2de82653d23339907cde55eca 350 Pfam PF01261 Xylose isomerase-like TIM barrel 30 279 2.1E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05515 3c5abdb2de82653d23339907cde55eca 350 Pfam PF07582 AP endonuclease family 2 C terminus 280 334 1.3E-21 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 6 30 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 PIRSF PIRSF000178 1 125 5.5E-38 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 119 3.3E-26 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 Gene3D G3DSA:1.20.5.540 2 13 4.9E-4 T 28-03-2018 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 4 122 2.8E-36 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 SUPERFAMILY SSF81343 3 124 1.63E-32 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08435 559af2fc1a8be3b1541f55a835fd383a 130 Gene3D G3DSA:1.20.1300.10 14 125 3.6E-28 T 28-03-2018 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 Pfam PF00072 Response regulator receiver domain 4 115 7.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 SUPERFAMILY SSF52172 1 133 1.14E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 SMART SM00448 2 115 9.0E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 SMART SM00421 150 207 1.0E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 SUPERFAMILY SSF46894 145 212 3.74E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 Gene3D G3DSA:1.10.10.10 127 213 2.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 Gene3D G3DSA:3.40.50.2300 1 126 9.5E-36 T 28-03-2018 SmaCSM2_RS05790 06654a2607dd2624a703ea3d00d70306 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS13290 6001c01d19c8576a65c34b28a05c2a17 273 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 4 272 71.139 T 28-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein SmaCSM2_RS13290 6001c01d19c8576a65c34b28a05c2a17 273 Pfam PF03618 Kinase/pyrophosphorylase 7 263 8.0E-71 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 SmaCSM2_RS10825 42405c8527c51114b3280f0981bed823 129 Pfam PF00593 TonB dependent receptor 20 127 7.4E-5 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10825 42405c8527c51114b3280f0981bed823 129 SUPERFAMILY SSF56935 25 129 8.79E-8 T 28-03-2018 SmaCSM2_RS10825 42405c8527c51114b3280f0981bed823 129 Gene3D G3DSA:2.40.170.20 7 128 2.2E-8 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 SUPERFAMILY SSF52172 33 156 1.46E-9 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 ProSitePatterns PS00622 LuxR-type HTH domain signature. 189 216 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 Gene3D G3DSA:1.10.10.10 158 231 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 Gene3D G3DSA:3.40.50.2300 14 157 9.6E-10 T 28-03-2018 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 SMART SM00421 172 229 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 Pfam PF00072 Response regulator receiver domain 35 148 4.4E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 SUPERFAMILY SSF46894 167 231 2.14E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS08675 fce72ff3048c8aef2f01db6daf1c15e4 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 174 229 2.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08055 c43982d8ccfd233195241f94d19f3129 179 SMART SM00463 93 177 4.7E-13 T 28-03-2018 IPR002625 Smr domain SmaCSM2_RS08055 c43982d8ccfd233195241f94d19f3129 179 SUPERFAMILY SSF160443 94 176 1.57E-16 T 28-03-2018 IPR002625 Smr domain SmaCSM2_RS08055 c43982d8ccfd233195241f94d19f3129 179 Pfam PF01713 Smr domain 96 176 7.3E-22 T 28-03-2018 IPR002625 Smr domain SmaCSM2_RS01550 090bde7aeaebde46dead7b965fdd3d40 190 SUPERFAMILY SSF56935 24 125 6.87E-9 T 28-03-2018 SmaCSM2_RS01550 090bde7aeaebde46dead7b965fdd3d40 190 Gene3D G3DSA:2.40.160.10 6 136 6.6E-10 T 28-03-2018 SmaCSM2_RS01550 090bde7aeaebde46dead7b965fdd3d40 190 TIGRFAM TIGR04273 Y_sulf_Ax21: sulfation-dependent quorum factor, Ax21 family 6 190 6.4E-89 T 28-03-2018 IPR026364 Ax21 family SmaCSM2_RS01550 090bde7aeaebde46dead7b965fdd3d40 190 Gene3D G3DSA:2.40.160.20 137 189 0.013 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 SMART SM00862 151 227 2.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 SUPERFAMILY SSF52172 7 132 4.84E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 SMART SM00448 9 119 2.3E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 2.7E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 Gene3D G3DSA:1.10.10.10 133 229 2.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 Gene3D G3DSA:3.40.50.2300 6 132 6.3E-34 T 28-03-2018 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 Pfam PF00072 Response regulator receiver domain 11 119 7.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS20715 31582f24cae9eae36b4b2c681430ad59 229 SUPERFAMILY SSF46894 136 227 1.22E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 Gene3D G3DSA:1.20.1250.20 267 507 8.8E-27 T 28-03-2018 SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 SUPERFAMILY SSF103473 472 500 7.72E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 SUPERFAMILY SSF103473 12 205 7.72E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 SUPERFAMILY SSF103473 256 426 7.72E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 Gene3D G3DSA:1.20.1250.20 10 209 2.3E-34 T 28-03-2018 SmaCSM2_RS11865 6b57c69dd8f160c51eda31c03d332fba 510 Pfam PF07690 Major Facilitator Superfamily 26 416 2.2E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS16590 bb65318503de791008ab8b4fcbb949e8 255 Pfam PF02517 CAAX protease self-immunity 113 211 5.9E-8 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SmaCSM2_RS17005 c9c1f3ee3ccb203a6ca20f070dac62bd 492 Gene3D G3DSA:3.40.710.10 35 387 1.1E-92 T 28-03-2018 SmaCSM2_RS17005 c9c1f3ee3ccb203a6ca20f070dac62bd 492 Pfam PF00144 Beta-lactamase 52 366 2.3E-78 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS17005 c9c1f3ee3ccb203a6ca20f070dac62bd 492 SUPERFAMILY SSF56601 50 363 3.06E-96 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS03780 ab2ce3435ee221f791a9ee412891e5df 424 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 21 309 21.684 T 28-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial SmaCSM2_RS03780 ab2ce3435ee221f791a9ee412891e5df 424 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 22 280 1.0E-71 T 28-03-2018 IPR017039 Virulence factor BrkB SmaCSM2_RS03780 ab2ce3435ee221f791a9ee412891e5df 424 Pfam PF03631 Virulence factor BrkB 33 279 4.8E-57 T 28-03-2018 IPR017039 Virulence factor BrkB SmaCSM2_RS01880 c7fe2fcd514897d7d01d9fa3d038c154 423 Pfam PF00924 Mechanosensitive ion channel 149 402 6.0E-46 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SmaCSM2_RS01880 c7fe2fcd514897d7d01d9fa3d038c154 423 Gene3D G3DSA:2.30.30.60 207 257 1.7E-10 T 28-03-2018 SmaCSM2_RS01880 c7fe2fcd514897d7d01d9fa3d038c154 423 SUPERFAMILY SSF50182 190 257 1.86E-10 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 SUPERFAMILY SSF56935 45 681 2.15E-136 T 28-03-2018 SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 Gene3D G3DSA:2.170.130.10 37 183 6.0E-40 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 Gene3D G3DSA:2.40.170.20 184 681 4.4E-86 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 172 8.9E-31 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 54 - T 28-03-2018 IPR010916 TonB box, conserved site SmaCSM2_RS18830 8ac57064fe29b0050620716c0e9d1db5 681 Pfam PF00593 TonB dependent receptor 271 679 2.3E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 Pfam PF02576 RimP N-terminal domain 11 89 3.1E-27 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 Gene3D G3DSA:2.30.30.180 94 156 3.8E-12 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 159 23.517 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 Pfam PF17384 RimP C-terminal SH3 domain 92 159 8.3E-19 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 SUPERFAMILY SSF75420 5 89 4.05E-20 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 SUPERFAMILY SSF74942 90 159 6.02E-13 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SmaCSM2_RS15095 c28e3d003efb6512ade1a8a1e8e6cb92 196 Gene3D G3DSA:3.30.300.70 1 86 9.0E-22 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 Gene3D G3DSA:3.30.420.40 1 148 5.5E-39 T 28-03-2018 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 2.7E-113 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 335 63.472 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 1.2E-129 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 4.8E-52 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 Gene3D G3DSA:3.30.420.40 149 293 1.8E-16 T 28-03-2018 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 SUPERFAMILY SSF53067 3 127 1.42E-30 T 28-03-2018 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 SUPERFAMILY SSF53067 105 313 1.62E-41 T 28-03-2018 SmaCSM2_RS01865 2372b07533e6b10be83dd01ea4f9df19 341 Pfam PF00814 Glycoprotease family 29 311 8.6E-100 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS08190 79494f9695c78019599cc7b0f376c5e2 340 Pfam PF04773 FecR protein 133 223 3.1E-15 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS08190 79494f9695c78019599cc7b0f376c5e2 340 Pfam PF16220 Domain of unknown function (DUF4880) 16 56 2.8E-10 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS08190 79494f9695c78019599cc7b0f376c5e2 340 PIRSF PIRSF018266 4 340 3.8E-57 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS05295 70ecb2664c4b513ab8b439ff95445262 179 SUPERFAMILY SSF55729 1 155 5.48E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05295 70ecb2664c4b513ab8b439ff95445262 179 Gene3D G3DSA:3.40.630.30 90 157 2.8E-13 T 28-03-2018 SmaCSM2_RS05295 70ecb2664c4b513ab8b439ff95445262 179 Pfam PF13673 Acetyltransferase (GNAT) domain 45 145 2.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS05295 70ecb2664c4b513ab8b439ff95445262 179 Gene3D G3DSA:3.40.630.30 1 89 2.4E-15 T 28-03-2018 SmaCSM2_RS17495 9a488e305298dfafd7b899e8ace0b52d 197 Gene3D G3DSA:3.40.50.10420 1 189 1.8E-47 T 28-03-2018 SmaCSM2_RS17495 9a488e305298dfafd7b899e8ace0b52d 197 SUPERFAMILY SSF100950 5 190 1.1E-47 T 28-03-2018 SmaCSM2_RS17495 9a488e305298dfafd7b899e8ace0b52d 197 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 184 2.4E-30 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SmaCSM2_RS17495 9a488e305298dfafd7b899e8ace0b52d 197 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 184 1.2E-46 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SmaCSM2_RS17495 9a488e305298dfafd7b899e8ace0b52d 197 PIRSF PIRSF006806 1 187 4.4E-29 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 Pfam PF08212 Lipocalin-like domain 33 174 8.5E-43 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 Gene3D G3DSA:2.40.128.20 1 175 4.2E-26 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 SUPERFAMILY SSF50814 9 174 1.9E-32 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 PRINTS PR01171 Bacterial lipocalin signature 136 147 9.7E-6 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 PRINTS PR01171 Bacterial lipocalin signature 33 47 9.7E-6 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 PRINTS PR01171 Bacterial lipocalin signature 163 173 9.7E-6 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 PRINTS PR01171 Bacterial lipocalin signature 121 129 9.7E-6 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 SmaCSM2_RS10535 f1f6fdf304c2f7401d0e1a17cda5228d 177 PIRSF PIRSF036893 1 177 1.9E-38 T 28-03-2018 IPR022271 Lipocalin, ApoD type SmaCSM2_RS15410 42fe8f2657f5e04f4251de853d753238 140 PIRSF PIRSF000714 3 139 6.2E-46 T 28-03-2018 IPR026026 Histidine triad hydrolase, Hint-type SmaCSM2_RS15410 42fe8f2657f5e04f4251de853d753238 140 SUPERFAMILY SSF54197 4 134 1.66E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SmaCSM2_RS15410 42fe8f2657f5e04f4251de853d753238 140 Gene3D G3DSA:3.30.428.10 2 135 5.6E-15 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SmaCSM2_RS15410 42fe8f2657f5e04f4251de853d753238 140 Pfam PF01230 HIT domain 12 100 2.4E-11 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SmaCSM2_RS00715 c9d8754d1dda074fad5b5514e4cd35e1 145 SUPERFAMILY SSF52821 22 143 2.88E-28 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS00715 c9d8754d1dda074fad5b5514e4cd35e1 145 Gene3D G3DSA:3.40.250.10 37 145 1.7E-27 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS00715 c9d8754d1dda074fad5b5514e4cd35e1 145 Pfam PF00581 Rhodanese-like domain 44 135 1.1E-17 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS00715 c9d8754d1dda074fad5b5514e4cd35e1 145 SMART SM00450 42 139 8.3E-21 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 23.215 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 SUPERFAMILY SSF54736 52 122 1.66E-21 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 122 1.0E-17 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 SUPERFAMILY SSF48300 4 59 5.75E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 50 5.6E-19 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 Gene3D G3DSA:3.30.1390.10 53 122 4.8E-23 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 57 122 5.0E-24 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 1.6E-42 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03950 5529f5928bb58c328858135a159e9790 122 Gene3D G3DSA:1.20.5.710 2 52 9.6E-19 T 28-03-2018 SmaCSM2_RS07370 5c7c32f1a0bb265f1f8e882aeff61de9 379 Pfam PF02687 FtsX-like permease family 288 374 1.3E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS01065 3596d37895695c04a277caa4aea85351 285 SUPERFAMILY SSF103481 184 285 7.85E-6 T 28-03-2018 SmaCSM2_RS01065 3596d37895695c04a277caa4aea85351 285 Pfam PF00892 EamA-like transporter family 2 132 3.3E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SUPERFAMILY SSF48452 431 560 1.52E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SUPERFAMILY SSF48452 220 325 4.22E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 Gene3D G3DSA:1.25.40.10 132 240 0.0031 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 Pfam PF13283 Bacteriophage N adsorption protein A C-term 822 939 1.1E-22 T 28-03-2018 IPR025137 Bacteriophage N4 adsorption protein A, C-terminal SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 Gene3D G3DSA:1.25.40.10 32 128 1.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SUPERFAMILY SSF48452 36 107 1.04E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SUPERFAMILY SSF48452 146 236 1.04E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SMART SM00028 144 177 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SMART SM00028 261 294 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SMART SM00028 426 459 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SMART SM00028 35 68 88.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 SMART SM00028 496 529 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 Gene3D G3DSA:1.25.40.10 428 942 1.5E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS03070 b63250eec679af0f40cfbb592626ff4d 944 Gene3D G3DSA:1.25.40.120 241 400 3.7E-10 T 28-03-2018 SmaCSM2_RS01935 4180c0c263f240e87e5a25cbc0845256 494 SUPERFAMILY SSF54001 295 428 1.28E-17 T 28-03-2018 SmaCSM2_RS01935 4180c0c263f240e87e5a25cbc0845256 494 SMART SM00460 352 416 8.6E-13 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS01935 4180c0c263f240e87e5a25cbc0845256 494 Pfam PF01841 Transglutaminase-like superfamily 310 413 3.9E-16 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 SUPERFAMILY SSF54862 1 491 7.12E-183 T 28-03-2018 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Gene3D G3DSA:3.30.70.20 236 360 9.2E-30 T 28-03-2018 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Gene3D G3DSA:3.30.70.20 361 466 1.1E-29 T 28-03-2018 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Gene3D G3DSA:3.30.70.20 198 235 9.2E-21 T 28-03-2018 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Gene3D G3DSA:3.30.70.20 5 197 1.1E-29 T 28-03-2018 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Pfam PF13247 4Fe-4S dicluster domain 175 271 2.9E-37 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 435 2.8E-28 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 SmaCSM2_RS12290 5d0ec6b0f541400b515d61f62609bff9 514 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 492 9.1E-298 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 100 225 7.1E-38 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 Gene3D G3DSA:3.30.1400.10 98 230 1.0E-39 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 SUPERFAMILY SSF64383 96 234 9.42E-37 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 100 228 6.0E-56 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 SMART SM00771 97 227 5.7E-55 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 Hamap MF_00509 Cell division protein ZipA [zipA]. 5 229 17.923 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 SmaCSM2_RS13880 cd8bbdfd01ed35cb60fb551b5c419a8e 245 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 93 227 3.7E-64 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 Gene3D G3DSA:2.60.40.10 152 241 3.5E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 171 231 9.5E-18 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 PRINTS PR00969 Pili chaperone signature 166 181 4.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 PRINTS PR00969 Pili chaperone signature 26 35 4.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 PRINTS PR00969 Pili chaperone signature 75 96 4.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 PRINTS PR00969 Pili chaperone signature 131 146 4.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 PRINTS PR00969 Pili chaperone signature 103 120 4.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 Gene3D G3DSA:2.60.40.10 25 150 6.4E-42 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 SUPERFAMILY SSF49584 143 234 1.2E-19 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 102 119 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 SUPERFAMILY SSF49354 20 149 6.92E-45 T 28-03-2018 IPR008962 PapD-like SmaCSM2_RS03040 03003f6222f32603bb882fe85e3938a5 242 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 25 150 6.4E-48 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 Gene3D G3DSA:3.40.50.620 5 150 9.4E-9 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 Gene3D G3DSA:3.40.50.620 151 276 1.8E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 SUPERFAMILY SSF52402 3 147 3.27E-8 T 28-03-2018 SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 Pfam PF00582 Universal stress protein family 156 274 1.4E-7 T 28-03-2018 IPR006016 UspA GO:0006950 SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 SUPERFAMILY SSF52402 156 275 4.35E-18 T 28-03-2018 SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 PRINTS PR01438 Universal stress protein signature 236 248 1.3E-5 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 PRINTS PR01438 Universal stress protein signature 155 173 1.3E-5 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS09410 bae9e4141f0399ca0e76181c33d322dd 276 PRINTS PR01438 Universal stress protein signature 254 276 1.3E-5 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS00125 f6f33a497b8e1bd19b61e9550c1a3228 575 SUPERFAMILY SSF52540 157 339 6.5E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00125 f6f33a497b8e1bd19b61e9550c1a3228 575 SUPERFAMILY SSF52540 3 112 6.5E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00125 f6f33a497b8e1bd19b61e9550c1a3228 575 Pfam PF13175 AAA ATPase domain 4 76 2.4E-9 T 28-03-2018 SmaCSM2_RS00125 f6f33a497b8e1bd19b61e9550c1a3228 575 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 252 323 6.1E-10 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SmaCSM2_RS00125 f6f33a497b8e1bd19b61e9550c1a3228 575 Gene3D G3DSA:3.40.50.300 3 343 1.8E-18 T 28-03-2018 SmaCSM2_RS07945 11c48ab2e7d8214b14802e2ab32b46a4 144 Gene3D G3DSA:3.10.50.40 25 144 7.6E-43 T 28-03-2018 SmaCSM2_RS07945 11c48ab2e7d8214b14802e2ab32b46a4 144 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 45 140 2.8E-33 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SmaCSM2_RS07945 11c48ab2e7d8214b14802e2ab32b46a4 144 SUPERFAMILY SSF54534 36 143 4.91E-39 T 28-03-2018 SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 Pfam PF01590 GAF domain 27 156 1.4E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 201 351 1.5E-35 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 SUPERFAMILY SSF55073 205 353 3.69E-42 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 SMART SM00267 189 355 1.4E-44 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 SUPERFAMILY SSF55781 28 164 5.89E-21 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 196 353 1.8E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 Gene3D G3DSA:3.30.450.40 21 197 2.4E-17 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 Gene3D G3DSA:3.30.70.270 198 356 1.1E-47 T 28-03-2018 SmaCSM2_RS06460 b8d9070163ffc42a91f8e6dc6b115802 356 SMART SM00065 26 169 0.0055 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 SUPERFAMILY SSF56935 68 727 1.68E-99 T 28-03-2018 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 727 2.3E-113 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 Pfam PF00593 TonB dependent receptor 247 727 1.5E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 Gene3D G3DSA:2.40.170.20 179 728 7.6E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 167 3.2E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00795 326b4f1d12ee17ce822e978abc55c5ab 729 Gene3D G3DSA:2.170.130.10 34 178 1.7E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS10050 33890d0700cac0ddd641ab49432ac9f8 102 Pfam PF13466 STAS domain 4 82 7.2E-14 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS10050 33890d0700cac0ddd641ab49432ac9f8 102 SUPERFAMILY SSF52091 3 88 1.49E-10 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS10050 33890d0700cac0ddd641ab49432ac9f8 102 Gene3D G3DSA:3.30.750.24 1 102 1.5E-8 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS13615 79e584456c52e998976561e80906aa40 116 Gene3D G3DSA:2.30.30.40 3 59 0.0037 T 28-03-2018 SmaCSM2_RS13615 79e584456c52e998976561e80906aa40 116 SUPERFAMILY SSF50044 68 112 4.98E-6 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS13615 79e584456c52e998976561e80906aa40 116 SUPERFAMILY SSF50044 3 58 5.71E-6 T 28-03-2018 IPR001452 SH3 domain GO:0005515 SmaCSM2_RS13615 79e584456c52e998976561e80906aa40 116 PIRSF PIRSF034961 1 116 2.1E-31 T 28-03-2018 IPR014593 Uncharacterised conserved protein UCP034961, SH3-2 SmaCSM2_RS13615 79e584456c52e998976561e80906aa40 116 Gene3D G3DSA:2.30.30.40 61 115 0.011 T 28-03-2018 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Pfam PF12848 ABC transporter 219 293 2.6E-9 T 28-03-2018 IPR032781 ABC-transporter extension domain SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Gene3D G3DSA:3.40.50.300 4 85 3.4E-9 T 28-03-2018 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Gene3D G3DSA:1.10.287.380 562 623 5.1E-5 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Gene3D G3DSA:3.40.50.300 286 540 4.5E-57 T 28-03-2018 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 SUPERFAMILY SSF52540 2 94 2.94E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 SUPERFAMILY SSF52540 121 230 2.94E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Gene3D G3DSA:3.40.50.300 86 285 1.1E-43 T 28-03-2018 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Pfam PF00005 ABC transporter 332 464 1.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Pfam PF00005 ABC transporter 20 180 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 SMART SM00382 28 225 1.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 SMART SM00382 339 510 4.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 Pfam PF16326 ABC transporter C-terminal domain 557 625 7.6E-23 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SmaCSM2_RS08925 66c8e8f9a0b7aac6101f3be57e81dec0 626 SUPERFAMILY SSF52540 308 511 5.8E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20940 50bf23a94fd67379ccb6699ca90ae4e6 294 Gene3D G3DSA:3.40.50.720 101 178 0.052 T 28-03-2018 SmaCSM2_RS20940 50bf23a94fd67379ccb6699ca90ae4e6 294 Gene3D G3DSA:3.40.50.20 9 100 4.5E-9 T 28-03-2018 SmaCSM2_RS20940 50bf23a94fd67379ccb6699ca90ae4e6 294 SUPERFAMILY SSF51735 15 293 2.1E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS20940 50bf23a94fd67379ccb6699ca90ae4e6 294 Gene3D G3DSA:3.90.25.10 179 294 3.4E-11 T 28-03-2018 SmaCSM2_RS04745 2ce6b167904daa8f75a254ac3ef1647f 175 PIRSF PIRSF004982 1 175 2.6E-48 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 SmaCSM2_RS04745 2ce6b167904daa8f75a254ac3ef1647f 175 Pfam PF03843 Outer membrane lipoprotein Slp family 15 166 2.1E-43 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 SmaCSM2_RS00495 c56dca44ce8b103bf0d4dcb0869d03e8 722 Gene3D G3DSA:3.40.50.1980 380 593 0.0032 T 28-03-2018 SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 Gene3D G3DSA:1.20.120.50 1 127 5.1E-38 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 Hamap MF_00556 Bacteriohemerythrin. 3 125 23.311 T 28-03-2018 IPR023504 Bacteriohemerythrin-like protein SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 Pfam PF01814 Hemerythrin HHE cation binding domain 13 123 1.2E-13 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 SUPERFAMILY SSF47188 1 126 3.53E-34 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 ProSitePatterns PS00550 Hemerythrin family signature. 57 80 - T 28-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 SmaCSM2_RS06995 e9e5c42ca201779c8c4d2787cc8a9c1a 153 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 6 126 3.0E-37 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 SmaCSM2_RS06185 a301ea5557e7ea89c9dd0ef6ada533e7 468 SUPERFAMILY SSF56954 7 451 2.35E-65 T 28-03-2018 SmaCSM2_RS06185 a301ea5557e7ea89c9dd0ef6ada533e7 468 Pfam PF02321 Outer membrane efflux protein 43 245 3.6E-15 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06185 a301ea5557e7ea89c9dd0ef6ada533e7 468 Pfam PF02321 Outer membrane efflux protein 271 449 3.9E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS06185 a301ea5557e7ea89c9dd0ef6ada533e7 468 Gene3D G3DSA:1.20.1600.10 27 453 1.7E-59 T 28-03-2018 SmaCSM2_RS15700 f649772ef32e02f19917e7e206e38a9a 147 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 29 146 8.5E-33 T 28-03-2018 IPR019223 Domain of unknown function DUF2147 SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.5E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 Gene3D G3DSA:1.10.357.10 1 195 1.2E-33 T 28-03-2018 SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09335 9d58a96d58b4f22d6ce3d6d6452e6c55 196 SUPERFAMILY SSF46689 3 81 1.5E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS07880 a1247084c32b02d3227453126921ecb6 133 Gene3D G3DSA:1.10.260.40 1 59 9.2E-6 T 28-03-2018 SmaCSM2_RS14285 8e957f0f40583128e3324910d8871947 722 Gene3D G3DSA:1.10.1370.10 498 722 6.0E-58 T 28-03-2018 SmaCSM2_RS14285 8e957f0f40583128e3324910d8871947 722 Gene3D G3DSA:1.10.1370.10 178 410 6.5E-45 T 28-03-2018 SmaCSM2_RS14285 8e957f0f40583128e3324910d8871947 722 SUPERFAMILY SSF55486 45 716 1.17E-175 T 28-03-2018 SmaCSM2_RS14285 8e957f0f40583128e3324910d8871947 722 Gene3D G3DSA:1.20.1050.40 43 177 1.8E-34 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal SmaCSM2_RS14285 8e957f0f40583128e3324910d8871947 722 Pfam PF01432 Peptidase family M3 264 716 8.2E-128 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 435 1.1E-121 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 Gene3D G3DSA:1.10.3370.10 12 445 1.4E-149 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 439 27.9 T 28-03-2018 IPR026593 Protein translocase subunit SecY SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 Pfam PF00344 SecY translocase 76 422 4.8E-109 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 ProSitePatterns PS00756 Protein secY signature 2. 175 192 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PIRSF PIRSF004557 12 447 1.4E-115 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 376 394 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 156 181 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 182 205 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 321 343 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 408 426 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 1.1E-87 T 28-03-2018 SmaCSM2_RS04090 d53849db12673755183dd874960a4524 455 SUPERFAMILY SSF103491 15 430 9.55E-122 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS02335 b562948ba70e0a45d46dff2e38af0d5c 404 Pfam PF07690 Major Facilitator Superfamily 31 230 6.5E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS02335 b562948ba70e0a45d46dff2e38af0d5c 404 SUPERFAMILY SSF103473 13 388 3.92E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS02335 b562948ba70e0a45d46dff2e38af0d5c 404 Gene3D G3DSA:1.20.1250.20 2 199 3.9E-12 T 28-03-2018 SmaCSM2_RS02335 b562948ba70e0a45d46dff2e38af0d5c 404 Gene3D G3DSA:1.20.1250.20 204 397 6.4E-17 T 28-03-2018 SmaCSM2_RS13160 706b8f1b499a08a7ec5a66d0967a0536 479 SUPERFAMILY SSF55073 309 463 5.23E-46 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS13160 706b8f1b499a08a7ec5a66d0967a0536 479 Pfam PF00990 Diguanylate cyclase, GGDEF domain 304 460 3.9E-45 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS13160 706b8f1b499a08a7ec5a66d0967a0536 479 SMART SM00267 293 465 5.3E-61 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS13160 706b8f1b499a08a7ec5a66d0967a0536 479 Gene3D G3DSA:3.30.70.270 292 467 4.8E-53 T 28-03-2018 SmaCSM2_RS13160 706b8f1b499a08a7ec5a66d0967a0536 479 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 302 463 4.7E-46 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS17190 ab096abbf98379940d9e5876a97aaaab 266 SUPERFAMILY SSF56281 12 247 1.27E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS17190 ab096abbf98379940d9e5876a97aaaab 266 Pfam PF00753 Metallo-beta-lactamase superfamily 12 203 2.2E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS17190 ab096abbf98379940d9e5876a97aaaab 266 SMART SM00849 14 203 1.8E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS17190 ab096abbf98379940d9e5876a97aaaab 266 Gene3D G3DSA:3.60.15.10 1 266 1.1E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS13360 9a0718791357cb1ec29b3087f8c0f0d3 441 Pfam PF01764 Lipase (class 3) 120 148 1.7E-5 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 SmaCSM2_RS13360 9a0718791357cb1ec29b3087f8c0f0d3 441 SUPERFAMILY SSF53474 8 184 2.18E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13360 9a0718791357cb1ec29b3087f8c0f0d3 441 Gene3D G3DSA:3.40.50.1820 2 435 1.5E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00412 Epoxide hydrolase signature 245 267 6.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00412 Epoxide hydrolase signature 44 59 6.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00412 Epoxide hydrolase signature 211 227 6.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00412 Epoxide hydrolase signature 24 42 6.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 SUPERFAMILY SSF53474 4 270 7.03E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 1.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 1.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 1.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 Gene3D G3DSA:3.40.50.1820 1 270 1.7E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS02135 a1e11d61031f43127e7ccc778b3760a9 270 Pfam PF00561 alpha/beta hydrolase fold 19 250 2.5E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09425 7734ddec08082acfd615f52e51e5de87 1229 Gene3D G3DSA:2.40.160.40 1132 1229 0.1 T 28-03-2018 SmaCSM2_RS09425 7734ddec08082acfd615f52e51e5de87 1229 Gene3D G3DSA:2.40.160.40 784 964 7.4E-4 T 28-03-2018 SmaCSM2_RS09425 7734ddec08082acfd615f52e51e5de87 1229 SUPERFAMILY SSF56935 839 964 6.41E-5 T 28-03-2018 SmaCSM2_RS09425 7734ddec08082acfd615f52e51e5de87 1229 Gene3D G3DSA:2.40.160.10 965 1117 0.1 T 28-03-2018 SmaCSM2_RS00765 66c42545866e054236b2ec85cbfe7628 191 Gene3D G3DSA:2.40.160.20 123 189 0.0059 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS00765 66c42545866e054236b2ec85cbfe7628 191 Pfam PF13505 Outer membrane protein beta-barrel domain 6 178 6.3E-8 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel SmaCSM2_RS00765 66c42545866e054236b2ec85cbfe7628 191 TIGRFAM TIGR04273 Y_sulf_Ax21: sulfation-dependent quorum factor, Ax21 family 7 191 2.7E-99 T 28-03-2018 IPR026364 Ax21 family SmaCSM2_RS00765 66c42545866e054236b2ec85cbfe7628 191 Gene3D G3DSA:2.40.160.10 15 122 5.5E-10 T 28-03-2018 SmaCSM2_RS00765 66c42545866e054236b2ec85cbfe7628 191 SUPERFAMILY SSF56935 21 126 4.19E-10 T 28-03-2018 SmaCSM2_RS06295 5418134c530bb08062fd925f18642dd0 224 Pfam PF04493 Endonuclease V 23 217 4.3E-68 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SmaCSM2_RS06295 5418134c530bb08062fd925f18642dd0 224 Hamap MF_00801 Endonuclease V [nfi]. 13 224 33.534 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 327 4.1E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 Gene3D G3DSA:3.50.50.60 139 335 1.9E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 6.7E-10 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.7E-10 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 6.7E-10 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 Gene3D G3DSA:3.50.50.60 1 138 5.9E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 3.1E-13 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.1E-13 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 3.1E-13 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 3.1E-13 T 28-03-2018 SmaCSM2_RS07490 ab6d11d250fa000cd293f9cf7b773716 435 SUPERFAMILY SSF51905 4 339 2.12E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS12740 81a582b7865cfe97f4fe2cd726b6cf0b 449 Gene3D G3DSA:3.30.450.90 97 202 4.3E-34 T 28-03-2018 SmaCSM2_RS12740 81a582b7865cfe97f4fe2cd726b6cf0b 449 Pfam PF00437 Type II/IV secretion system protein 103 378 6.4E-76 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS12740 81a582b7865cfe97f4fe2cd726b6cf0b 449 Gene3D G3DSA:3.40.50.300 226 435 1.1E-14 T 28-03-2018 SmaCSM2_RS12740 81a582b7865cfe97f4fe2cd726b6cf0b 449 SUPERFAMILY SSF52540 82 408 1.91E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20305 f66f050a3de3ae616c4050b812d1f4b5 609 Gene3D G3DSA:3.40.50.300 12 392 3.0E-12 T 28-03-2018 SmaCSM2_RS20305 f66f050a3de3ae616c4050b812d1f4b5 609 SUPERFAMILY SSF52540 289 389 1.3E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20305 f66f050a3de3ae616c4050b812d1f4b5 609 SUPERFAMILY SSF52540 94 262 1.3E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 246 1.9E-60 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 PRINTS PR01713 Nucleotide sugar epimerase signature 279 296 4.2E-23 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 PRINTS PR01713 Nucleotide sugar epimerase signature 214 229 4.2E-23 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 4.2E-23 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 PRINTS PR01713 Nucleotide sugar epimerase signature 240 255 4.2E-23 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 Gene3D G3DSA:3.90.25.10 190 318 1.3E-30 T 28-03-2018 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 Gene3D G3DSA:3.40.50.720 1 189 5.0E-42 T 28-03-2018 SmaCSM2_RS21330 5993cfb6220b58c16d2f9829b3bd4702 321 SUPERFAMILY SSF51735 1 316 2.42E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 SUPERFAMILY SSF46785 3 83 6.47E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 Gene3D G3DSA:3.40.190.10 178 259 2.6E-18 T 28-03-2018 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 SUPERFAMILY SSF53850 88 286 1.71E-36 T 28-03-2018 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 Gene3D G3DSA:1.10.10.10 1 87 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 Gene3D G3DSA:3.40.190.10 94 177 1.9E-19 T 28-03-2018 SmaCSM2_RS16770 79d28c155b2f2e12cba93e80999b8add 288 Pfam PF03466 LysR substrate binding domain 91 286 4.7E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 SUPERFAMILY SSF56935 28 269 8.24E-83 T 28-03-2018 SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 SUPERFAMILY SSF56935 298 772 8.24E-83 T 28-03-2018 SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 Gene3D G3DSA:2.170.130.10 26 166 3.3E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 130 5.9E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 Pfam PF00593 TonB dependent receptor 264 769 2.2E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12470 ec5c4253cedee8c332e73687a282fc3c 772 Gene3D G3DSA:2.40.170.20 167 772 3.3E-62 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 364 87.01 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 358 6.6E-81 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 ProSitePatterns PS00618 RecF protein signature 2. 304 322 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 SUPERFAMILY SSF52540 1 339 1.98E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 ProSitePatterns PS00617 RecF protein signature 1. 121 141 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 Gene3D G3DSA:3.40.50.300 1 361 4.8E-26 T 28-03-2018 SmaCSM2_RS00015 d5f291bab2537a5df6f72ee2276d11ca 364 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 341 2.8E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SmaCSM2_RS00590 61cc25716bcfb9d027c7abdfbe87b20c 344 PIRSF PIRSF005211 10 344 9.1E-61 T 28-03-2018 IPR012020 AB hydrolase 4 family SmaCSM2_RS00590 61cc25716bcfb9d027c7abdfbe87b20c 344 Gene3D G3DSA:3.40.50.1820 52 343 1.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00590 61cc25716bcfb9d027c7abdfbe87b20c 344 SUPERFAMILY SSF53474 57 198 4.67E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00590 61cc25716bcfb9d027c7abdfbe87b20c 344 SUPERFAMILY SSF53474 273 340 4.67E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00590 61cc25716bcfb9d027c7abdfbe87b20c 344 Pfam PF12146 Serine aminopeptidase, S33 81 296 9.3E-13 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 Gene3D G3DSA:3.40.50.300 2 211 1.1E-52 T 28-03-2018 SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 14 192 3.8E-70 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 SMART SM00072 13 195 1.4E-56 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 Pfam PF00625 Guanylate kinase 15 192 3.3E-48 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 SUPERFAMILY SSF52540 13 197 1.77E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 Hamap MF_00328 Guanylate kinase [gmk]. 12 195 34.953 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SmaCSM2_RS17380 ef2be1536ea3f09951af7626f7d734d9 221 ProSitePatterns PS00856 Guanylate kinase-like signature. 48 65 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SmaCSM2_RS00540 1eb2e67bb51ddd4e8026e657ade2c75c 204 Gene3D G3DSA:3.40.50.150 4 203 3.7E-19 T 28-03-2018 SmaCSM2_RS00540 1eb2e67bb51ddd4e8026e657ade2c75c 204 SUPERFAMILY SSF53335 12 202 1.53E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS00540 1eb2e67bb51ddd4e8026e657ade2c75c 204 Pfam PF06080 Protein of unknown function (DUF938) 4 202 1.2E-72 T 28-03-2018 IPR010342 Protein of unknown function DUF938 SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 SUPERFAMILY SSF54211 22 128 7.84E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 Pfam PF00825 Ribonuclease P 22 127 4.4E-26 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 38 120 5.0E-13 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 22 130 18.715 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 71 85 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 Gene3D G3DSA:3.30.230.10 19 132 2.6E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SmaCSM2_RS21765 c8ef98d46fd92ed6cc78db43138373ba 164 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 26 128 3.3E-19 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 85 24.007 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 SUPERFAMILY SSF50249 11 87 2.1E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 11 81 1.8E-34 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 Gene3D G3DSA:2.40.50.140 9 89 1.2E-30 T 28-03-2018 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 11 81 5.0E-35 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 Pfam PF00366 Ribosomal protein S17 15 82 9.9E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 PRINTS PR00973 Ribosomal protein S17 family signature 61 71 5.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 PRINTS PR00973 Ribosomal protein S17 family signature 29 52 5.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04035 68e5640d6fd27b1b98a587c2417cf902 89 PRINTS PR00973 Ribosomal protein S17 family signature 71 78 5.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 10 179 30.865 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 ProSitePatterns PS00938 Initiation factor 3 signature. 67 80 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 17 179 2.2E-63 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 SUPERFAMILY SSF55200 92 179 1.57E-30 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 Gene3D G3DSA:3.30.110.10 88 180 7.3E-33 T 28-03-2018 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 SUPERFAMILY SSF54364 15 87 7.19E-29 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 17 85 8.5E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 92 177 2.0E-35 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SmaCSM2_RS15030 130af3e28e905669881280b7f7713434 180 Gene3D G3DSA:3.10.20.80 11 87 7.8E-32 T 28-03-2018 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 SUPERFAMILY SSF50249 1 63 4.34E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Gene3D G3DSA:1.10.8.10 150 195 1.3E-8 T 28-03-2018 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Pfam PF07499 RuvA, C-terminal domain 151 194 3.8E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Pfam PF01330 RuvA N terminal domain 1 62 8.7E-21 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Gene3D G3DSA:2.40.50.140 1 66 1.2E-23 T 28-03-2018 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Gene3D G3DSA:1.10.150.20 67 137 3.5E-16 T 28-03-2018 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 SUPERFAMILY SSF47781 66 134 1.25E-20 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 SMART SM00278 108 127 0.046 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 SMART SM00278 73 92 4.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Pfam PF14520 Helix-hairpin-helix domain 72 130 4.4E-19 T 28-03-2018 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 196 1.4E-48 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 SUPERFAMILY SSF46929 151 194 6.54E-8 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SmaCSM2_RS16710 d849d137548be1db19f1cf3b9d9005c7 197 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 30.37 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Gene3D G3DSA:3.40.640.10 147 455 2.8E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 27 141 1.6E-25 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 390 404 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 SUPERFAMILY SSF55904 613 760 8.24E-41 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 147 593 7.0E-162 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Gene3D G3DSA:3.90.1150.10 457 642 6.3E-60 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Gene3D G3DSA:3.90.100.10 643 762 5.3E-33 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 PIRSF PIRSF009393 9 762 1.8E-278 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 618 748 2.7E-48 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 Gene3D G3DSA:3.40.50.220 58 146 2.2E-4 T 28-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 SmaCSM2_RS13070 8f665a4689b9eca00759febc68a04aa2 762 SUPERFAMILY SSF53383 147 611 3.06E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS03635 31221ca7799a91dc3876fc7518778058 228 SUPERFAMILY SSF55068 23 219 7.46E-79 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS03635 31221ca7799a91dc3876fc7518778058 228 Pfam PF01625 Peptide methionine sulfoxide reductase 56 209 2.1E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS03635 31221ca7799a91dc3876fc7518778058 228 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 55 209 1.2E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS03635 31221ca7799a91dc3876fc7518778058 228 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 53 215 38.361 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS03635 31221ca7799a91dc3876fc7518778058 228 Gene3D G3DSA:3.30.1060.10 41 223 6.0E-76 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 SUPERFAMILY SSF46894 159 232 1.12E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 SUPERFAMILY SSF75516 8 162 8.24E-12 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 Pfam PF03472 Autoinducer binding domain 18 156 3.4E-13 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 Gene3D G3DSA:3.30.450.80 3 162 1.8E-23 T 28-03-2018 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 226 2.7E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 6.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 6.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 6.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 TIGRFAM TIGR03541 reg_near_HchA: LuxR family transcriptional regulatory, chaperone HchA-associated 3 232 8.6E-94 T 28-03-2018 IPR019941 Transcription regulator LuxR, chaperone HchA-associated SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 Gene3D G3DSA:1.10.10.10 163 234 8.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08640 1585d463c92ee78cf84aec7864e10eaf 234 SMART SM00421 169 226 7.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS09330 ebd6f1f47083d7413f37c92d4521d386 267 Pfam PF01636 Phosphotransferase enzyme family 48 259 3.6E-31 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SmaCSM2_RS09330 ebd6f1f47083d7413f37c92d4521d386 267 Gene3D G3DSA:3.30.200.20 1 97 4.7E-19 T 28-03-2018 SmaCSM2_RS09330 ebd6f1f47083d7413f37c92d4521d386 267 PIRSF PIRSF000706 4 267 9.0E-90 T 28-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 SmaCSM2_RS09330 ebd6f1f47083d7413f37c92d4521d386 267 Gene3D G3DSA:3.90.1200.10 105 267 4.0E-20 T 28-03-2018 SmaCSM2_RS09330 ebd6f1f47083d7413f37c92d4521d386 267 SUPERFAMILY SSF56112 15 267 7.14E-51 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS06395 372e1a0e96be2ef2e41d7e144d3e9f42 59 Pfam PF17067 Ribosomal protein S31e 2 38 7.5E-9 T 28-03-2018 SmaCSM2_RS06395 372e1a0e96be2ef2e41d7e144d3e9f42 59 TIGRFAM TIGR04560 ribo_THX: ribosomal small subunit protein bTHX 1 24 2.6E-12 T 28-03-2018 IPR030826 30S ribosomal protein GO:0005840 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 12 449 2.5E-94 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 Gene3D G3DSA:2.30.42.10 26 197 2.3E-6 T 28-03-2018 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 Gene3D G3DSA:2.30.42.10 219 308 9.9E-12 T 28-03-2018 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 Pfam PF13180 PDZ domain 234 287 3.7E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 SUPERFAMILY SSF50156 89 184 3.02E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 Pfam PF02163 Peptidase family M50 11 436 2.1E-75 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SmaCSM2_RS06610 7e5f6e832e4e01e1613bc8189fb328d6 452 SUPERFAMILY SSF50156 221 310 4.86E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS15280 84b5cb6ab57cea42ec77e0509f8b7018 218 SUPERFAMILY SSF51366 8 210 4.39E-52 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS15280 84b5cb6ab57cea42ec77e0509f8b7018 218 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 8 212 37.059 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 SmaCSM2_RS15280 84b5cb6ab57cea42ec77e0509f8b7018 218 Gene3D G3DSA:3.20.20.70 7 214 5.7E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS15280 84b5cb6ab57cea42ec77e0509f8b7018 218 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 11 207 2.8E-41 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SUPERFAMILY SSF55781 318 483 9.6E-23 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Gene3D G3DSA:3.30.450.40 312 526 4.7E-27 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Gene3D G3DSA:3.30.450.40 113 311 5.9E-21 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SMART SM00052 700 943 2.0E-93 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SUPERFAMILY SSF141868 706 943 4.58E-78 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SUPERFAMILY SSF55073 533 692 4.24E-44 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Gene3D G3DSA:3.30.70.270 527 698 1.6E-56 T 28-03-2018 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Gene3D G3DSA:3.20.20.450 699 946 1.1E-88 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SMART SM00267 517 690 1.6E-60 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 524 689 2.4E-38 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Pfam PF00990 Diguanylate cyclase, GGDEF domain 528 685 3.8E-43 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Pfam PF13185 GAF domain 138 283 3.4E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Pfam PF13185 GAF domain 339 476 8.4E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SMART SM00065 138 293 0.026 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SMART SM00065 339 486 5.1E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 SUPERFAMILY SSF55781 117 287 3.27E-15 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08805 9ffe7cbb163ab43110358a7cbd5a7f1a 946 Pfam PF00563 EAL domain 706 938 4.5E-66 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS12515 699ea7ae5282f323c457d86c516d8f78 398 Gene3D G3DSA:1.20.1250.20 213 398 1.5E-22 T 28-03-2018 SmaCSM2_RS12515 699ea7ae5282f323c457d86c516d8f78 398 Gene3D G3DSA:1.20.1250.20 7 209 8.0E-26 T 28-03-2018 SmaCSM2_RS12515 699ea7ae5282f323c457d86c516d8f78 398 SUPERFAMILY SSF103473 11 392 1.12E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12515 699ea7ae5282f323c457d86c516d8f78 398 Pfam PF07690 Major Facilitator Superfamily 15 238 4.4E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS13740 2e0e10118893426383f6635190fd8836 127 Gene3D G3DSA:3.10.450.50 1 126 1.4E-17 T 28-03-2018 SmaCSM2_RS13740 2e0e10118893426383f6635190fd8836 127 SUPERFAMILY SSF54427 6 125 1.98E-17 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS13740 2e0e10118893426383f6635190fd8836 127 Pfam PF12680 SnoaL-like domain 11 122 6.1E-13 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SmaCSM2_RS02260 e693ae1486d6c902f3d88f9e4b47645a 140 Gene3D G3DSA:3.10.180.10 1 140 1.8E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS02260 e693ae1486d6c902f3d88f9e4b47645a 140 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 134 3.6E-6 T 28-03-2018 IPR028973 PhnB-like SmaCSM2_RS02260 e693ae1486d6c902f3d88f9e4b47645a 140 SUPERFAMILY SSF54593 1 137 7.83E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS14725 bc6e2f491ec963297230b8b2b21a7dd4 288 Gene3D G3DSA:3.30.2010.10 65 158 1.2E-22 T 28-03-2018 SmaCSM2_RS14725 bc6e2f491ec963297230b8b2b21a7dd4 288 Pfam PF01435 Peptidase family M48 74 284 1.1E-41 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SmaCSM2_RS14725 bc6e2f491ec963297230b8b2b21a7dd4 288 Hamap MF_00188 Protease HtpX [htpX]. 2 285 25.516 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 Pfam PF02049 Flagellar hook-basal body complex protein FliE 44 120 2.9E-27 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 10 121 16.254 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 50 66 4.6E-11 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 106 119 4.6E-11 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 85 101 4.6E-11 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS10185 ca5a97bcda0aef816408f103078fc439 121 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 49 119 1.1E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 SmaCSM2_RS05230 6916a2569b627471d05ca16b54eea660 201 Gene3D G3DSA:2.60.120.10 118 198 3.6E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS05230 6916a2569b627471d05ca16b54eea660 201 Pfam PF05962 HutD 18 193 5.8E-48 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves SmaCSM2_RS05230 6916a2569b627471d05ca16b54eea660 201 SUPERFAMILY SSF51182 12 198 1.54E-49 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS05230 6916a2569b627471d05ca16b54eea660 201 Gene3D G3DSA:2.60.120.10 16 117 8.8E-42 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 PIRSF PIRSF000521 28 156 8.6E-9 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 PIRSF PIRSF000521 202 449 1.3E-23 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 Gene3D G3DSA:3.90.1150.10 337 450 5.3E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 Gene3D G3DSA:3.40.640.10 203 336 3.8E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 SUPERFAMILY SSF53383 22 446 1.46E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 Gene3D G3DSA:3.90.1150.10 1 202 3.2E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS06980 f6c60be22284cbdfa069dab710485ee5 450 Pfam PF00202 Aminotransferase class-III 29 444 1.1E-96 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS04145 23d8bbed364f6efde215cceb29e1a9db 540 SUPERFAMILY SSF75304 44 527 3.79E-130 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SmaCSM2_RS04145 23d8bbed364f6efde215cceb29e1a9db 540 Pfam PF01425 Amidase 67 510 1.2E-94 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SmaCSM2_RS04145 23d8bbed364f6efde215cceb29e1a9db 540 Gene3D G3DSA:3.90.1300.10 38 540 1.7E-157 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SmaCSM2_RS18140 35e5403966194bacd99f3b7b839b4518 183 Pfam PF01551 Peptidase family M23 80 177 5.2E-19 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS18140 35e5403966194bacd99f3b7b839b4518 183 Gene3D G3DSA:2.70.70.10 45 183 7.5E-28 T 28-03-2018 SmaCSM2_RS18140 35e5403966194bacd99f3b7b839b4518 183 SUPERFAMILY SSF51261 59 182 4.76E-29 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 34 413 41.271 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 Pfam PF02684 Lipid-A-disaccharide synthetase 37 402 4.4E-110 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 32 410 1.2E-112 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 Gene3D G3DSA:3.40.50.2000 212 408 1.5E-18 T 28-03-2018 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 Gene3D G3DSA:3.40.50.2000 29 211 5.3E-7 T 28-03-2018 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 SUPERFAMILY SSF53756 36 329 8.72E-35 T 28-03-2018 SmaCSM2_RS06585 61d3d1c137e0cd6fb3b6006de9a85b2f 419 SUPERFAMILY SSF53756 361 411 8.72E-35 T 28-03-2018 SmaCSM2_RS00265 f0da776ccb7f703450122f5cb202502c 337 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 78 298 3.8E-32 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SmaCSM2_RS00265 f0da776ccb7f703450122f5cb202502c 337 Gene3D G3DSA:3.60.160.10 70 322 2.2E-73 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SmaCSM2_RS00265 f0da776ccb7f703450122f5cb202502c 337 SUPERFAMILY SSF51219 77 315 1.91E-77 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SmaCSM2_RS00265 f0da776ccb7f703450122f5cb202502c 337 Pfam PF01987 Mitochondrial biogenesis AIM24 79 296 1.2E-64 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SmaCSM2_RS05195 47067b2c1a334a469c7e18e990036846 236 SUPERFAMILY SSF53448 1 232 7.43E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS05195 47067b2c1a334a469c7e18e990036846 236 Gene3D G3DSA:3.90.550.10 1 235 1.9E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS05195 47067b2c1a334a469c7e18e990036846 236 Pfam PF00483 Nucleotidyl transferase 2 123 9.4E-16 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SmaCSM2_RS09345 c7c96bb61e1ffd171490b4e2ccb1bd4d 334 SUPERFAMILY SSF56112 5 287 5.93E-33 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS09345 c7c96bb61e1ffd171490b4e2ccb1bd4d 334 Gene3D G3DSA:3.30.200.20 1 104 1.4E-5 T 28-03-2018 SmaCSM2_RS09345 c7c96bb61e1ffd171490b4e2ccb1bd4d 334 Gene3D G3DSA:3.90.1200.10 108 292 2.1E-18 T 28-03-2018 SmaCSM2_RS09345 c7c96bb61e1ffd171490b4e2ccb1bd4d 334 Pfam PF01636 Phosphotransferase enzyme family 27 278 1.4E-19 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SmaCSM2_RS00910 4b5d59f9e8f500c281ddd6e775176972 551 Gene3D G3DSA:3.30.200.20 100 243 4.2E-24 T 28-03-2018 SmaCSM2_RS00910 4b5d59f9e8f500c281ddd6e775176972 551 Pfam PF03109 ABC1 family 110 227 4.4E-35 T 28-03-2018 IPR004147 UbiB domain SmaCSM2_RS00910 4b5d59f9e8f500c281ddd6e775176972 551 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 444 1.3E-182 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 SmaCSM2_RS00910 4b5d59f9e8f500c281ddd6e775176972 551 SUPERFAMILY SSF56112 92 155 3.98E-37 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS00910 4b5d59f9e8f500c281ddd6e775176972 551 SUPERFAMILY SSF56112 190 432 3.98E-37 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS08955 7ef70696f5dbf9b9cf44c7b8270d4a17 406 TIGRFAM TIGR00261 traB: TraB family protein 28 397 1.1E-85 T 28-03-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal SmaCSM2_RS08955 7ef70696f5dbf9b9cf44c7b8270d4a17 406 Pfam PF01963 TraB family 20 241 8.6E-26 T 28-03-2018 IPR002816 Pheromone shutdown, TraB SmaCSM2_RS00260 30a3a2b35a508795844b3372f354cf36 330 Gene3D G3DSA:3.40.1090.10 37 257 6.1E-43 T 28-03-2018 SmaCSM2_RS00260 30a3a2b35a508795844b3372f354cf36 330 Pfam PF01734 Patatin-like phospholipase 48 204 5.5E-29 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 SmaCSM2_RS00260 30a3a2b35a508795844b3372f354cf36 330 SUPERFAMILY SSF52151 36 294 3.4E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 SUPERFAMILY SSF53955 30 159 2.78E-18 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Pfam PF01471 Putative peptidoglycan binding domain 211 271 2.8E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Pfam PF01471 Putative peptidoglycan binding domain 305 364 3.0E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Pfam PF00182 Chitinase class I 45 113 1.2E-4 T 28-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 SUPERFAMILY SSF47090 297 371 5.65E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Gene3D G3DSA:1.10.101.10 194 278 5.1E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Gene3D G3DSA:1.10.101.10 294 373 8.9E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 SUPERFAMILY SSF47090 202 272 2.35E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS13830 2b9777af7aca9dd23fda2aa045f68fab 543 Gene3D G3DSA:3.30.20.10 45 111 4.2E-9 T 28-03-2018 SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 SUPERFAMILY SSF52402 1 141 2.34E-29 T 28-03-2018 SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 Gene3D G3DSA:3.40.50.620 1 148 6.8E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 PRINTS PR01438 Universal stress protein signature 103 115 2.0E-6 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 PRINTS PR01438 Universal stress protein signature 121 143 2.0E-6 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-6 T 28-03-2018 IPR006015 Universal stress protein A SmaCSM2_RS18015 2ea8dc1fd7fa244aa7af977fd4af349f 148 Pfam PF00582 Universal stress protein family 1 141 8.1E-25 T 28-03-2018 IPR006016 UspA GO:0006950 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 Gene3D G3DSA:2.30.40.10 1 70 5.2E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 SUPERFAMILY SSF51556 55 376 1.84E-90 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 ProSitePatterns PS00483 Dihydroorotase signature 2. 312 323 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 SUPERFAMILY SSF51338 1 54 1.8E-31 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 SUPERFAMILY SSF51338 376 439 1.8E-31 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 Pfam PF01979 Amidohydrolase family 52 429 1.5E-19 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SmaCSM2_RS14665 ee7cf9691b1a201d45421bbdc61f1418 448 Gene3D G3DSA:3.20.20.140 71 392 2.9E-93 T 28-03-2018 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 SUPERFAMILY SSF64263 1 119 1.44E-49 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 Gene3D G3DSA:3.90.1030.10 1 117 3.4E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 4.3E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.639 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04115 9259e67f4f9b4399cba0fdc81be07b3c 127 Pfam PF01196 Ribosomal protein L17 20 116 5.4E-32 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS10795 55d23aeeede59bad5e8457c12baff2e4 87 ProSitePatterns PS01047 Heavy-metal-associated domain. 5 34 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SmaCSM2_RS10795 55d23aeeede59bad5e8457c12baff2e4 87 Pfam PF00403 Heavy-metal-associated domain 5 59 1.2E-9 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10795 55d23aeeede59bad5e8457c12baff2e4 87 SUPERFAMILY SSF55008 3 59 1.83E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10795 55d23aeeede59bad5e8457c12baff2e4 87 Gene3D G3DSA:3.30.70.100 1 62 2.5E-14 T 28-03-2018 SmaCSM2_RS17670 6d32f26044801fab8a06a349fcf4c5b8 311 Pfam PF16220 Domain of unknown function (DUF4880) 17 56 2.4E-7 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS17670 6d32f26044801fab8a06a349fcf4c5b8 311 PIRSF PIRSF018266 6 311 9.2E-58 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS17670 6d32f26044801fab8a06a349fcf4c5b8 311 Pfam PF04773 FecR protein 110 196 9.1E-18 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS09300 a6bb202378b90a0717b16d55eab4ae8c 358 SUPERFAMILY SSF56281 195 343 1.35E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS09300 a6bb202378b90a0717b16d55eab4ae8c 358 SUPERFAMILY SSF56281 94 168 1.35E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS09300 a6bb202378b90a0717b16d55eab4ae8c 358 PIRSF PIRSF038896 15 351 1.4E-89 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 SmaCSM2_RS09300 a6bb202378b90a0717b16d55eab4ae8c 358 Gene3D G3DSA:3.60.15.10 79 355 1.7E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS09300 a6bb202378b90a0717b16d55eab4ae8c 358 Pfam PF12706 Beta-lactamase superfamily domain 111 303 2.6E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS07800 5c21329c149b94001f7b31d9f487f64c 70 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 62 4.4E-24 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA SmaCSM2_RS07800 5c21329c149b94001f7b31d9f487f64c 70 Gene3D G3DSA:1.10.10.10 14 70 4.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 Gene3D G3DSA:3.40.50.150 82 442 5.0E-55 T 28-03-2018 SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 SUPERFAMILY SSF53335 75 443 7.58E-80 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 Gene3D G3DSA:2.40.50.140 1 81 2.8E-23 T 28-03-2018 SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 14 444 68.983 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 269 443 3.6E-24 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 426 436 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 436 3.1E-96 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 374 404 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site SmaCSM2_RS15920 5e12adf326e0c1725beeb645510d02ce 444 SUPERFAMILY SSF50249 13 73 2.97E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS07825 0e13a26b1e282c71eacf9d9559759436 213 Pfam PF01613 Flavin reductase like domain 20 195 5.6E-8 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS07825 0e13a26b1e282c71eacf9d9559759436 213 Gene3D G3DSA:2.30.110.10 7 210 5.4E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS07825 0e13a26b1e282c71eacf9d9559759436 213 SUPERFAMILY SSF50475 16 198 7.25E-25 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS03775 b67cbad034c49f1e698e858a4b4f061a 197 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 195 1.5E-45 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 SmaCSM2_RS03775 b67cbad034c49f1e698e858a4b4f061a 197 SUPERFAMILY SSF52218 1 195 7.47E-56 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS03775 b67cbad034c49f1e698e858a4b4f061a 197 Pfam PF03358 NADPH-dependent FMN reductase 35 139 2.7E-8 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS03775 b67cbad034c49f1e698e858a4b4f061a 197 Gene3D G3DSA:3.40.50.360 2 197 1.8E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS05155 c1ff6062ecd8d00def0856719d7578f1 219 Pfam PF00551 Formyl transferase 6 182 3.1E-49 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS05155 c1ff6062ecd8d00def0856719d7578f1 219 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 6 189 27.527 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SmaCSM2_RS05155 c1ff6062ecd8d00def0856719d7578f1 219 Gene3D G3DSA:3.40.50.170 1 201 3.6E-61 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS05155 c1ff6062ecd8d00def0856719d7578f1 219 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 6 190 2.4E-59 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SmaCSM2_RS05155 c1ff6062ecd8d00def0856719d7578f1 219 SUPERFAMILY SSF53328 6 195 2.75E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 SUPERFAMILY SSF88659 122 184 5.61E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 52 83 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 183 3.1E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 Gene3D G3DSA:1.10.1740.10 15 90 2.6E-17 T 28-03-2018 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 Gene3D G3DSA:1.10.10.10 91 189 2.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 Pfam PF04542 Sigma-70 region 2 33 96 2.6E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 Pfam PF08281 Sigma-70, region 4 132 180 9.7E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05850 e8255ff4028ad5ae938c12d907ee704c 405 SUPERFAMILY SSF88946 12 105 6.02E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS06215 9bb0f75c9f17f99ef920195ac3fba495 294 SUPERFAMILY SSF52768 42 239 9.36E-11 T 28-03-2018 SmaCSM2_RS06215 9bb0f75c9f17f99ef920195ac3fba495 294 Gene3D G3DSA:3.40.800.10 21 249 7.8E-37 T 28-03-2018 SmaCSM2_RS06215 9bb0f75c9f17f99ef920195ac3fba495 294 Pfam PF00491 Arginase family 42 239 1.2E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS00375 0f0a2da67c846823bc036bfaedaf9575 67 Pfam PF04325 Protein of unknown function (DUF465) 13 58 8.8E-13 T 28-03-2018 IPR007420 Protein of unknown function DUF465 SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 Gene3D G3DSA:3.10.580.10 1 142 8.7E-29 T 28-03-2018 SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 Pfam PF00571 CBS domain 72 124 8.9E-12 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 Pfam PF00571 CBS domain 12 61 2.8E-9 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 SUPERFAMILY SSF54631 12 141 1.26E-32 T 28-03-2018 SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 SMART SM00116 14 61 1.1E-5 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS16340 be63e6cf6064425157153d67a60a461c 143 SMART SM00116 79 126 4.0E-9 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS19895 6af53d5dc23a420125bd06f3c44d205c 402 Gene3D G3DSA:3.50.50.60 18 397 2.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19895 6af53d5dc23a420125bd06f3c44d205c 402 Pfam PF01266 FAD dependent oxidoreductase 30 382 4.0E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SmaCSM2_RS19895 6af53d5dc23a420125bd06f3c44d205c 402 SUPERFAMILY SSF51905 345 391 9.06E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19895 6af53d5dc23a420125bd06f3c44d205c 402 SUPERFAMILY SSF51905 29 252 9.06E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 SMART SM00855 2 158 6.5E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 PIRSF PIRSF000709 1 180 7.8E-13 T 28-03-2018 SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 Gene3D G3DSA:3.40.50.1240 1 210 3.5E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 SUPERFAMILY SSF53254 1 203 9.82E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS04255 637aed28b171a2667b18e224a8a35870 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 198 9.4E-57 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS11480 7f871f300be6bd87c08dae6d59827a29 246 Gene3D G3DSA:3.40.570.10 13 227 7.6E-38 T 28-03-2018 SmaCSM2_RS11480 7f871f300be6bd87c08dae6d59827a29 246 Pfam PF01223 DNA/RNA non-specific endonuclease 22 219 3.0E-36 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SmaCSM2_RS11480 7f871f300be6bd87c08dae6d59827a29 246 SUPERFAMILY SSF54060 20 221 1.71E-41 T 28-03-2018 SmaCSM2_RS11480 7f871f300be6bd87c08dae6d59827a29 246 SMART SM00477 28 226 6.4E-11 T 28-03-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 SmaCSM2_RS11480 7f871f300be6bd87c08dae6d59827a29 246 SMART SM00892 27 226 4.1E-30 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SmaCSM2_RS17430 c15a76c4ff4913ad91864c5a35ac7253 286 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 286 3.0E-79 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 SmaCSM2_RS17430 c15a76c4ff4913ad91864c5a35ac7253 286 Pfam PF08340 Domain of unknown function (DUF1732) 202 286 1.8E-34 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 SmaCSM2_RS17430 c15a76c4ff4913ad91864c5a35ac7253 286 Pfam PF03755 YicC-like family, N-terminal region 2 152 3.3E-36 T 28-03-2018 IPR013527 YicC-like, N-terminal SmaCSM2_RS21420 6ea029af022cd87b5f525b2aaeafda4f 1285 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 953 1283 1.3E-59 T 28-03-2018 IPR007452 Translocation and assembly module TamB SmaCSM2_RS19480 c78a8cbf31042d3b37d902e00bcae50e 248 Gene3D G3DSA:3.10.260.10 1 106 7.2E-13 T 28-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 SmaCSM2_RS19480 c78a8cbf31042d3b37d902e00bcae50e 248 SUPERFAMILY SSF54616 3 117 4.05E-17 T 28-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 SmaCSM2_RS19480 c78a8cbf31042d3b37d902e00bcae50e 248 Pfam PF04383 KilA-N domain 10 110 1.3E-20 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding SmaCSM2_RS19480 c78a8cbf31042d3b37d902e00bcae50e 248 SMART SM01252 13 111 3.8E-17 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 Pfam PF01734 Patatin-like phospholipase 287 398 5.3E-6 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 Pfam PF01734 Patatin-like phospholipase 14 63 1.5E-9 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 Gene3D G3DSA:3.40.1090.10 5 519 1.5E-26 T 28-03-2018 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 SUPERFAMILY SSF52151 11 79 3.5E-9 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 SUPERFAMILY SSF52151 383 403 3.5E-9 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 SUPERFAMILY SSF52151 197 267 3.5E-9 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS01165 0b0804d570d1e2a73809104a731ede10 630 SUPERFAMILY SSF52151 305 347 3.5E-9 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SmaCSM2_RS12595 e916974086046e7b4cd8dd310bb68906 155 SUPERFAMILY SSF52218 2 146 2.73E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS12595 e916974086046e7b4cd8dd310bb68906 155 Gene3D G3DSA:3.40.50.360 1 142 5.5E-18 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS12595 e916974086046e7b4cd8dd310bb68906 155 Pfam PF00258 Flavodoxin 3 105 1.0E-7 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SmaCSM2_RS02880 dfbb8126879f703642b44b02c1965b0e 273 SUPERFAMILY SSF103481 39 133 1.02E-11 T 28-03-2018 SmaCSM2_RS02880 dfbb8126879f703642b44b02c1965b0e 273 Pfam PF00892 EamA-like transporter family 142 270 8.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS02880 dfbb8126879f703642b44b02c1965b0e 273 SUPERFAMILY SSF103481 171 271 5.62E-14 T 28-03-2018 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 Pfam PF02574 Homocysteine S-methyltransferase 24 347 3.5E-80 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 SUPERFAMILY SSF82282 14 43 2.49E-102 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 SUPERFAMILY SSF82282 73 358 2.49E-102 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 PIRSF PIRSF037505 312 362 6.5E-4 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 PIRSF PIRSF037505 78 256 5.8E-5 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 SmaCSM2_RS14025 a35242dca6bc4210d49a229f224f741e 363 Gene3D G3DSA:3.20.20.330 9 359 1.6E-113 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 SMART SM01001 8 159 4.1E-98 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 Gene3D G3DSA:3.40.50.7700 2 167 1.8E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 SUPERFAMILY SSF52255 9 165 1.44E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 PIRSF PIRSF001338 6 167 9.1E-65 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 163 32.039 T 28-03-2018 IPR033747 Class I PurE SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 164 7.1E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SmaCSM2_RS07180 5900f93477e294ed325f5bb433a09a9a 167 Pfam PF00731 AIR carboxylase 10 157 9.6E-62 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SmaCSM2_RS18880 881f33bbba5f82d1e2e462da71730ef3 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 111 1.1E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS18880 881f33bbba5f82d1e2e462da71730ef3 116 SUPERFAMILY SSF54593 7 112 5.77E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18880 881f33bbba5f82d1e2e462da71730ef3 116 Gene3D G3DSA:3.10.180.10 6 116 2.3E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SUPERFAMILY SSF55073 372 530 5.73E-46 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SMART SM00091 245 311 4.1E-4 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Pfam PF00563 EAL domain 550 781 6.6E-57 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 527 3.6E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Gene3D G3DSA:3.30.450.20 187 372 2.2E-17 T 28-03-2018 SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SUPERFAMILY SSF55785 235 354 6.98E-16 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Pfam PF13426 PAS domain 256 355 1.0E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SMART SM00086 315 356 2.2E-5 T 28-03-2018 IPR001610 PAC motif SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SMART SM00267 356 528 1.1E-54 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Gene3D G3DSA:3.30.70.270 373 535 2.5E-55 T 28-03-2018 SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Gene3D G3DSA:3.20.20.450 543 792 5.2E-72 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SUPERFAMILY SSF141868 548 788 1.7E-67 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 SMART SM00052 538 786 2.4E-61 T 28-03-2018 IPR001633 EAL domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 242 362 1.9E-13 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS06445 86a71ed084c02f0205026f31bea70432 807 Pfam PF00990 Diguanylate cyclase, GGDEF domain 367 524 6.5E-41 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS12315 7d7cff656135118b8c4efe06ff92496c 166 Pfam PF02391 MoaE protein 15 125 4.1E-28 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12315 7d7cff656135118b8c4efe06ff92496c 166 Gene3D G3DSA:3.90.1170.40 6 154 1.9E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS12315 7d7cff656135118b8c4efe06ff92496c 166 SUPERFAMILY SSF54690 15 149 3.27E-36 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SmaCSM2_RS21520 851d09aaa4f26fcb06250b84b9f50d6d 181 Pfam PF10947 Protein of unknown function (DUF2628) 63 132 4.5E-9 T 28-03-2018 IPR024399 Protein of unknown function DUF2628 SmaCSM2_RS16450 6cdcbe7987a4cbecb68a7b38c45d6b63 187 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS16450 6cdcbe7987a4cbecb68a7b38c45d6b63 187 Gene3D G3DSA:3.90.79.10 12 187 3.5E-30 T 28-03-2018 SmaCSM2_RS16450 6cdcbe7987a4cbecb68a7b38c45d6b63 187 SUPERFAMILY SSF55811 11 185 4.06E-36 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS16450 6cdcbe7987a4cbecb68a7b38c45d6b63 187 Pfam PF00293 NUDIX domain 49 167 3.7E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS15565 149b8ac5148752d81f5834c5f9ceea80 1285 Pfam PF13116 Protein of unknown function 506 780 1.1E-37 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 SmaCSM2_RS15565 149b8ac5148752d81f5834c5f9ceea80 1285 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 10 1259 0.0 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 SmaCSM2_RS15565 149b8ac5148752d81f5834c5f9ceea80 1285 Pfam PF13502 AsmA-like C-terminal region 1009 1251 4.9E-59 T 28-03-2018 IPR032712 AsmA-like, C-terminal SmaCSM2_RS16190 c7cee794ca1a90b16cc31f67a764e333 85 Gene3D G3DSA:1.10.1220.10 4 44 4.7E-12 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SmaCSM2_RS16190 c7cee794ca1a90b16cc31f67a764e333 85 SUPERFAMILY SSF47598 1 41 8.89E-11 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SmaCSM2_RS16190 c7cee794ca1a90b16cc31f67a764e333 85 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 6 70 9.6E-5 T 28-03-2018 IPR022789 Antitoxin ParD SmaCSM2_RS16190 c7cee794ca1a90b16cc31f67a764e333 85 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 68 1.0E-16 T 28-03-2018 IPR022789 Antitoxin ParD SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 Pfam PF00107 Zinc-binding dehydrogenase 158 273 2.8E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 Gene3D G3DSA:3.40.50.720 142 313 9.0E-30 T 28-03-2018 SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 2.6E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 SMART SM00829 11 327 2.9E-29 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 Gene3D G3DSA:3.90.180.10 1 141 3.3E-36 T 28-03-2018 SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 SUPERFAMILY SSF50129 3 151 1.73E-36 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS13825 741d814d84b6bff08bfd656336d076df 329 SUPERFAMILY SSF51735 118 275 7.54E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 SUPERFAMILY SSF56935 37 350 3.4E-86 T 28-03-2018 SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 SUPERFAMILY SSF56935 393 791 3.4E-86 T 28-03-2018 SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 162 1.3E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 Pfam PF00593 TonB dependent receptor 388 790 3.4E-34 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 Gene3D G3DSA:2.170.130.10 34 177 2.3E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08210 1a10f56ddc3aa8365dd6acc92f239c98 792 Gene3D G3DSA:2.40.170.20 178 791 1.5E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 92 570 5.1E-205 T 28-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 390 404 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 SUPERFAMILY SSF160246 14 155 4.18E-24 T 28-03-2018 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 Pfam PF00437 Type II/IV secretion system protein 198 462 7.9E-86 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 SUPERFAMILY SSF52540 180 570 1.18E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 49 158 4.8E-14 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 SMART SM00382 323 444 8.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 Gene3D G3DSA:3.40.50.300 297 573 5.3E-57 T 28-03-2018 SmaCSM2_RS02960 3e1efaff12f91a9984c4b19996ce8a5d 573 Gene3D G3DSA:3.30.450.90 162 295 1.7E-46 T 28-03-2018 SmaCSM2_RS19630 aa472da75a5963af1d1a98e21b06e51a 69 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 1.2E-13 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SmaCSM2_RS04130 a33601e53dce631afba0be35cf0557a0 463 Gene3D G3DSA:3.20.20.70 268 410 9.4E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS04130 a33601e53dce631afba0be35cf0557a0 463 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 21 462 1.1E-221 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SmaCSM2_RS04130 a33601e53dce631afba0be35cf0557a0 463 SUPERFAMILY SSF51569 18 457 6.88E-182 T 28-03-2018 SmaCSM2_RS04130 a33601e53dce631afba0be35cf0557a0 463 Pfam PF01474 Class-II DAHP synthetase family 21 455 3.4E-189 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 82 134 5.9E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 83 111 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 PRINTS PR01650 Bacterial translocase SecE signature 77 97 2.9E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 PRINTS PR01650 Bacterial translocase SecE signature 56 77 2.9E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 PRINTS PR01650 Bacterial translocase SecE signature 101 121 2.9E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 82 135 1.4E-20 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 Gene3D G3DSA:1.20.5.1030 80 131 2.7E-19 T 28-03-2018 SmaCSM2_RS03920 f6e56c091f9517e999998e1cd829d8db 137 Hamap MF_00422 Protein translocase subunit SecE [secE]. 75 133 11.79 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 SUPERFAMILY SSF53448 5 228 7.21E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 Gene3D G3DSA:3.90.550.10 2 232 2.2E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 227 39.738 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 228 2.4E-63 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 103 110 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SmaCSM2_RS08040 30bbd76490d2826e325b3d5dc2ebec3f 232 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 227 1.4E-70 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SmaCSM2_RS20880 07bcbeaec210f9c08bcd64b637d0171d 394 Gene3D G3DSA:3.40.1710.10 80 197 7.4E-7 T 28-03-2018 SmaCSM2_RS20880 07bcbeaec210f9c08bcd64b637d0171d 394 Pfam PF12698 ABC-2 family transporter protein 24 381 4.4E-22 T 28-03-2018 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 Pfam PF01416 tRNA pseudouridine synthase 145 240 3.4E-25 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 238 1.1E-58 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 Gene3D G3DSA:3.30.70.660 106 240 2.5E-35 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 244 30.668 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 PIRSF PIRSF001430 1 254 1.1E-64 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 SUPERFAMILY SSF55120 1 251 4.03E-81 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15285 f2dd053027d379cb363cf1c823a0187a 256 Gene3D G3DSA:3.30.70.580 1 105 1.7E-28 T 28-03-2018 SmaCSM2_RS07345 21c3a91d1c1874bee7b840b63ea6b0d0 208 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 191 1.8E-53 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SmaCSM2_RS07345 21c3a91d1c1874bee7b840b63ea6b0d0 208 PIRSF PIRSF000847 1 199 1.6E-43 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SmaCSM2_RS07345 21c3a91d1c1874bee7b840b63ea6b0d0 208 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 7.5E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS07345 21c3a91d1c1874bee7b840b63ea6b0d0 208 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 365 382 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 37 51 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 313 324 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 163 176 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 336 350 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PRINTS PR00148 Enolase signature 107 123 9.8E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 425 4.2E-131 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 PIRSF PIRSF001400 1 427 1.1E-185 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 6.3E-203 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 SUPERFAMILY SSF51604 143 427 1.3E-125 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 SUPERFAMILY SSF54826 4 136 2.08E-54 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 SMART SM01192 141 427 1.3E-217 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 SMART SM01193 4 134 6.6E-93 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 Gene3D G3DSA:3.20.20.120 129 430 6.6E-100 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 Hamap MF_00318 Enolase [eno]. 2 413 44.135 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 Pfam PF03952 Enolase, N-terminal domain 4 134 5.4E-58 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS08030 38543c37031d3be9fafe360cc76db78a 430 Gene3D G3DSA:3.30.390.10 3 127 6.3E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 356 1.2E-138 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 146 162 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 13 355 6.1E-130 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 10 358 50.096 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 Gene3D G3DSA:3.20.20.210 4 360 1.4E-110 T 28-03-2018 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 SUPERFAMILY SSF51726 7 359 2.09E-120 T 28-03-2018 SmaCSM2_RS16255 8cac4f91b182ca88eeb4ac2c772cd1ef 360 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 26 35 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SmaCSM2_RS18045 e30daf08c77f7d6a3b49c3984b28af59 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 87 1.7E-21 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SmaCSM2_RS18045 e30daf08c77f7d6a3b49c3984b28af59 91 Gene3D G3DSA:1.10.357.10 1 91 7.4E-4 T 28-03-2018 SmaCSM2_RS19660 5fa414d47b139caa6b220d12b7d8b6bb 214 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 54 211 2.5E-36 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS19660 5fa414d47b139caa6b220d12b7d8b6bb 214 SUPERFAMILY SSF47240 44 187 6.47E-18 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS19660 5fa414d47b139caa6b220d12b7d8b6bb 214 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 14 214 29.143 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 SmaCSM2_RS19660 5fa414d47b139caa6b220d12b7d8b6bb 214 Gene3D G3DSA:1.20.1260.10 44 190 1.0E-20 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS01970 a267d70de2db47f6a17d812ed62dbdff 250 SUPERFAMILY SSF56784 11 222 3.99E-28 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01970 a267d70de2db47f6a17d812ed62dbdff 250 Gene3D G3DSA:1.10.150.240 27 96 2.2E-25 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS01970 a267d70de2db47f6a17d812ed62dbdff 250 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 193 2.4E-8 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01970 a267d70de2db47f6a17d812ed62dbdff 250 Gene3D G3DSA:3.40.50.1000 97 249 8.7E-22 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Pfam PF04675 DNA ligase N terminus 3 166 3.9E-20 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Gene3D G3DSA:3.30.470.30 161 344 2.8E-31 T 28-03-2018 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Gene3D G3DSA:2.40.50.140 413 535 1.0E-23 T 28-03-2018 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Gene3D G3DSA:3.30.1490.70 345 408 1.1E-20 T 28-03-2018 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Pfam PF01068 ATP dependent DNA ligase domain 228 409 8.9E-36 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 SUPERFAMILY SSF56091 206 409 3.6E-55 T 28-03-2018 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 533 2.0E-188 T 28-03-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 Pfam PF04679 ATP dependent DNA ligase C terminal region 430 519 1.6E-9 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 SUPERFAMILY SSF117018 3 172 1.44E-5 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SmaCSM2_RS15865 715bf8597798141e1d0f1a087bd60b8b 535 SUPERFAMILY SSF50249 414 533 1.06E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS11395 ed2b805756ba781f7bb5a4680bb47d7a 344 Gene3D G3DSA:3.20.20.210 1 344 1.7E-90 T 28-03-2018 SmaCSM2_RS11395 ed2b805756ba781f7bb5a4680bb47d7a 344 PIRSF PIRSF005632 1 344 5.3E-197 T 28-03-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit SmaCSM2_RS11395 ed2b805756ba781f7bb5a4680bb47d7a 344 SUPERFAMILY SSF51726 5 341 3.14E-69 T 28-03-2018 SmaCSM2_RS11395 ed2b805756ba781f7bb5a4680bb47d7a 344 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 335 2.3E-38 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 162 174 6.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 134 145 6.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 133 6.7E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 Gene3D G3DSA:1.10.10.10 1 69 3.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 TIGRFAM TIGR00498 lexA: repressor LexA 2 209 4.2E-55 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 Gene3D G3DSA:2.10.109.10 92 209 5.5E-20 T 28-03-2018 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 SUPERFAMILY SSF51306 86 208 4.71E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 SUPERFAMILY SSF46785 1 69 1.85E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 Pfam PF00717 Peptidase S24-like 126 191 1.8E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 Hamap MF_00015 LexA repressor [lexA]. 2 210 30.813 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SmaCSM2_RS08140 ceef5ea66c4a577812cdec3dc8ec8c70 211 Pfam PF01726 LexA DNA binding domain 2 64 2.4E-19 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 Gene3D G3DSA:2.60.40.380 44 144 8.9E-16 T 28-03-2018 SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 45 140 1.9E-14 T 28-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 Pfam PF00149 Calcineurin-like phosphoesterase 149 347 3.8E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 SUPERFAMILY SSF56300 147 419 2.48E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 SUPERFAMILY SSF49363 39 141 9.68E-11 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SmaCSM2_RS08565 506f268bc27d3dc95c1f45e4514e853c 455 Gene3D G3DSA:3.60.21.10 145 447 5.8E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Gene3D G3DSA:3.40.50.10490 2 126 1.3E-23 T 28-03-2018 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Gene3D G3DSA:3.40.50.10490 237 470 1.0E-96 T 28-03-2018 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 243 256 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 SUPERFAMILY SSF53697 3 488 2.0E-159 T 28-03-2018 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 456 473 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 40 483 37.971 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Gene3D G3DSA:1.10.1390.10 471 504 1.8E-11 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 134 153 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 316 337 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 456 469 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 239 257 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 424 442 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 PRINTS PR00662 Glucose-6-phosphate isomerase signature 442 456 2.3E-46 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Pfam PF00342 Phosphoglucose isomerase 47 492 8.8E-151 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS08365 b231ae6c1dfd17e5e5a3fe9322117d4e 504 Gene3D G3DSA:3.40.50.10490 127 236 9.5E-31 T 28-03-2018 SmaCSM2_RS06885 7d692bbf8e0888c698729e96abbd8780 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 278 2.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS06885 7d692bbf8e0888c698729e96abbd8780 287 Gene3D G3DSA:1.10.3720.10 4 276 7.6E-32 T 28-03-2018 SmaCSM2_RS06885 7d692bbf8e0888c698729e96abbd8780 287 SUPERFAMILY SSF161098 27 275 1.31E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS06885 7d692bbf8e0888c698729e96abbd8780 287 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 18 279 5.4E-86 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SmaCSM2_RS15295 ca755e24346b0410b51ac357bb408e18 675 Gene3D G3DSA:1.20.5.170 351 472 2.3E-4 T 28-03-2018 SmaCSM2_RS15295 ca755e24346b0410b51ac357bb408e18 675 Gene3D G3DSA:3.10.350.10 194 318 1.2E-7 T 28-03-2018 SmaCSM2_RS15295 ca755e24346b0410b51ac357bb408e18 675 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 214 287 5.4E-20 T 28-03-2018 IPR020012 Motility protein FimV, N-terminal SmaCSM2_RS15295 ca755e24346b0410b51ac357bb408e18 675 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 632 674 7.9E-13 T 28-03-2018 IPR020011 Motility protein FimV, C-terminal SmaCSM2_RS12220 ac4147b205438e5d8ceaaa08449382ee 243 Pfam PF03591 AzlC protein 30 170 3.4E-37 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease SmaCSM2_RS01235 1b4d3ffa763ca4e450c7a4c1cc5d6b7f 102 Pfam PF08748 Phage tail assembly chaperone 5 102 6.9E-6 T 28-03-2018 IPR014859 Phage tail assembly chaperone SmaCSM2_RS01830 8ac1d70d2c91917d37c30239769bd780 269 SUPERFAMILY SSF159501 26 186 5.23E-6 T 28-03-2018 SmaCSM2_RS17140 af7eed19e68dd107c330adf664a1b809 380 Gene3D G3DSA:2.60.120.380 168 241 0.0026 T 28-03-2018 SmaCSM2_RS17140 af7eed19e68dd107c330adf664a1b809 380 Gene3D G3DSA:2.60.120.380 25 135 4.5E-10 T 28-03-2018 SmaCSM2_RS17140 af7eed19e68dd107c330adf664a1b809 380 Gene3D G3DSA:2.60.120.380 247 348 4.5E-7 T 28-03-2018 SmaCSM2_RS17140 af7eed19e68dd107c330adf664a1b809 380 Gene3D G3DSA:2.60.120.260 136 167 0.16 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS00690 5c003ea879ae0615f248f5833cbb0987 431 Pfam PF07219 HemY protein N-terminus 33 131 1.3E-18 T 28-03-2018 IPR010817 HemY, N-terminal SmaCSM2_RS00690 5c003ea879ae0615f248f5833cbb0987 431 Gene3D G3DSA:1.25.20.10 80 404 5.0E-15 T 28-03-2018 SmaCSM2_RS00690 5c003ea879ae0615f248f5833cbb0987 431 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 8 377 3.7E-44 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 Pfam PF00171 Aldehyde dehydrogenase family 18 479 1.2E-176 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 Gene3D G3DSA:3.40.309.10 268 465 6.0E-70 T 28-03-2018 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 10 477 3.7E-223 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 4 490 58.047 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 Gene3D G3DSA:3.40.605.10 1 267 5.5E-106 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09930 c73759623276f8932324968cd7c0a0db 490 SUPERFAMILY SSF53720 4 483 6.28E-172 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 SMART SM00563 349 476 2.1E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 SUPERFAMILY SSF69593 308 533 1.02E-27 T 28-03-2018 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 Pfam PF01553 Acyltransferase 334 473 3.4E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 Gene3D G3DSA:3.40.1130.10 289 564 4.4E-35 T 28-03-2018 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 PIRSF PIRSF000437 64 876 0.0 T 28-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 PIRSF PIRSF500064 40 877 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 58 861 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 SmaCSM2_RS00370 8fe8cd22bcd954b4799c0be92c53e10d 878 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 54 865 29.653 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 SUPERFAMILY SSF46894 131 232 6.65E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 4.2E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 SMART SM00862 155 231 3.7E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 SUPERFAMILY SSF52172 2 129 2.56E-40 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 Pfam PF00072 Response regulator receiver domain 6 117 6.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 SMART SM00448 4 116 1.1E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 Gene3D G3DSA:3.40.50.2300 1 127 8.8E-38 T 28-03-2018 SmaCSM2_RS02560 3cecb2eed264c706305d6b1c63fbab02 239 Gene3D G3DSA:1.10.10.10 128 237 4.4E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12495 a4d3f0222f1aab8ea4f835ca26053b83 85 Pfam PF00550 Phosphopantetheine attachment site 12 71 8.6E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS12495 a4d3f0222f1aab8ea4f835ca26053b83 85 SUPERFAMILY SSF47336 11 83 3.8E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS12495 a4d3f0222f1aab8ea4f835ca26053b83 85 Gene3D G3DSA:1.10.1200.10 2 85 2.7E-11 T 28-03-2018 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 SUPERFAMILY SSF48371 502 636 1.32E-36 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 227 242 7.5E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 311 7.5E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 7.5E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 328 343 7.5E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 347 359 7.5E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 Gene3D G3DSA:1.10.390.10 317 485 4.5E-38 T 28-03-2018 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 SMART SM01263 497 636 4.3E-47 T 28-03-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 KEGG: 00590+3.3.2.6 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 Pfam PF01433 Peptidase family M1 domain 253 465 2.1E-48 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 SUPERFAMILY SSF63737 45 244 5.89E-39 T 28-03-2018 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 SUPERFAMILY SSF55486 251 490 4.88E-67 T 28-03-2018 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 Gene3D G3DSA:2.60.40.1730 37 244 2.4E-39 T 28-03-2018 SmaCSM2_RS18400 73cf82ed787e33fb7d7454ea258f5391 642 Pfam PF09127 Leukotriene A4 hydrolase, C-terminal 525 636 1.0E-25 T 28-03-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 KEGG: 00590+3.3.2.6 SmaCSM2_RS04870 ceef17a9aa51069c0418c32ebd52f4c6 501 Pfam PF03929 PepSY-associated TM region 14 278 2.0E-11 T 28-03-2018 IPR005625 PepSY-associated TM protein SmaCSM2_RS16430 25fea1a4133d74428e90da985b72854e 100 Pfam PF06127 Protein of unknown function (DUF962) 4 97 5.1E-36 T 28-03-2018 IPR009305 Protein of unknown function DUF962 SmaCSM2_RS05290 e5b4be33790adbca81991c282abf8b1a 110 SUPERFAMILY SSF50022 4 105 1.57E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS05290 e5b4be33790adbca81991c282abf8b1a 110 Pfam PF00355 Rieske [2Fe-2S] domain 5 95 4.3E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS05290 e5b4be33790adbca81991c282abf8b1a 110 Gene3D G3DSA:2.102.10.10 2 110 2.2E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 Gene3D G3DSA:3.90.950.10 1 188 8.9E-53 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 PIRSF PIRSF006305 1 188 1.4E-40 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 Hamap MF_00528 Septum formation protein Maf [maf]. 2 188 28.624 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 SUPERFAMILY SSF52972 2 183 5.56E-55 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 Pfam PF02545 Maf-like protein 3 183 2.7E-42 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS04770 a76decd50e96051c141e8b8f7c892eee 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 4.7E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SmaCSM2_RS13140 32b17c9302fbf634f7550a09aa0e3755 318 SUPERFAMILY SSF143081 112 308 5.49E-31 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SmaCSM2_RS13140 32b17c9302fbf634f7550a09aa0e3755 318 Pfam PF02586 SOS response associated peptidase (SRAP) 122 305 6.9E-16 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SmaCSM2_RS13140 32b17c9302fbf634f7550a09aa0e3755 318 Gene3D G3DSA:3.90.1680.10 1 315 3.4E-29 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 SUPERFAMILY SSF103473 235 494 3.66E-10 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 Gene3D G3DSA:1.20.1250.20 279 493 2.9E-13 T 28-03-2018 SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 SUPERFAMILY SSF103473 9 214 1.22E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 Pfam PF00854 POT family 97 456 3.7E-59 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 Gene3D G3DSA:1.20.1250.20 13 215 5.8E-21 T 28-03-2018 SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS19815 6e0092004d188592c42174ce4e19f6ee 499 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 495 1.7E-102 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 SUPERFAMILY SSF52172 2 182 4.12E-34 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 SMART SM00448 2 113 7.6E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 Gene3D G3DSA:1.10.10.10 122 227 4.0E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 Pfam PF00072 Response regulator receiver domain 4 113 4.5E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 Gene3D G3DSA:3.40.50.2300 1 121 3.7E-30 T 28-03-2018 SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 SMART SM00862 148 223 5.1E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS13210 c3619f2fe26ef79879b599ba14855563 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 89 1.0E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 SMART SM00829 10 325 9.7E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 Gene3D G3DSA:3.90.180.10 1 143 3.7E-26 T 28-03-2018 SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 4 327 3.6E-133 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 SUPERFAMILY SSF51735 118 289 7.55E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 Gene3D G3DSA:3.40.50.720 144 270 1.4E-19 T 28-03-2018 SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 SUPERFAMILY SSF50129 3 147 3.65E-42 T 28-03-2018 IPR011032 GroES-like SmaCSM2_RS13565 aa85f024f5ddf9f8eca819d934116ba8 329 Pfam PF00107 Zinc-binding dehydrogenase 160 286 5.9E-13 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SmaCSM2_RS00045 a3c0566a4b9693335c9682c8ca1b1ee5 253 Pfam PF01618 MotA/TolQ/ExbB proton channel family 114 236 1.1E-36 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 Hamap MF_01970 Kynureninase [kynU]. 1 422 45.058 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 Pfam PF00266 Aminotransferase class-V 156 360 1.6E-6 T 28-03-2018 IPR000192 Aminotransferase class V domain SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 Gene3D G3DSA:3.40.640.10 48 317 5.0E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 Gene3D G3DSA:3.90.1150.10 318 423 2.3E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 PIRSF PIRSF038800 3 422 2.4E-154 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 TIGRFAM TIGR01814 kynureninase: kynureninase 12 421 5.1E-141 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SmaCSM2_RS13945 61b700dc9b1ff222fa20d34f234ab4e5 424 SUPERFAMILY SSF53383 7 420 7.22E-70 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS12015 b5814c9355f869725210da5ae9eb3dfb 113 Gene3D G3DSA:3.40.1620.10 11 61 4.7E-7 T 28-03-2018 SmaCSM2_RS12015 b5814c9355f869725210da5ae9eb3dfb 113 SUPERFAMILY SSF143120 22 64 1.44E-6 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SmaCSM2_RS12015 b5814c9355f869725210da5ae9eb3dfb 113 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 25 73 2.6E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SmaCSM2_RS12015 b5814c9355f869725210da5ae9eb3dfb 113 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 26 57 5.1E-6 T 28-03-2018 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 15 198 38.999 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 20 197 2.4E-65 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 Gene3D G3DSA:1.10.286.10 17 65 3.8E-22 T 28-03-2018 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 125 135 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 Pfam PF01227 GTP cyclohydrolase I 20 197 5.1E-72 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 SUPERFAMILY SSF55620 11 198 4.3E-74 T 28-03-2018 SmaCSM2_RS21580 8246adcbc01d9ffc88f8ed93600dbd6e 203 Gene3D G3DSA:3.30.1130.10 66 200 6.4E-53 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 Gene3D G3DSA:3.40.50.300 825 1068 0.024 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 Pfam PF13555 P-loop containing region of AAA domain 25 84 6.3E-22 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 Pfam PF13558 Putative exonuclease SbcCD, C subunit 971 1058 2.3E-20 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 Gene3D G3DSA:1.20.120.330 629 756 3.1E-4 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 Gene3D G3DSA:3.40.50.300 24 566 2.6E-15 T 28-03-2018 SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 SUPERFAMILY SSF52540 922 1071 7.17E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21565 23f3b318d625d8dfd7110ed6307b3b6b 1126 SUPERFAMILY SSF52540 29 74 7.17E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 492 19.636 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 526 1.0E-116 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 Pfam PF03023 MviN-like protein 27 492 1.2E-119 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PIRSF PIRSF002869 1 532 3.4E-139 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 359 378 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 131 155 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 50 66 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 434 451 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 31 50 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 261 287 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS05910 62157477f28cfa876fb747445afa3e76 534 PRINTS PR01806 Virulence factor MviN signature 155 176 4.3E-70 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 Pfam PF02195 ParB-like nuclease domain 49 136 6.4E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 Gene3D G3DSA:3.90.1530.10 38 136 6.9E-36 T 28-03-2018 SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 SMART SM00470 46 136 1.0E-37 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 45 216 2.5E-58 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 SUPERFAMILY SSF110849 46 180 2.82E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SmaCSM2_RS21340 bc991b94fe4f2131eb56e858f81daec7 307 Gene3D G3DSA:1.10.10.730 137 184 7.5E-19 T 28-03-2018 SmaCSM2_RS09285 00a018e7ef42fae2d1353f0156827df7 324 SUPERFAMILY SSF53850 75 304 7.03E-40 T 28-03-2018 SmaCSM2_RS09285 00a018e7ef42fae2d1353f0156827df7 324 Gene3D G3DSA:3.40.190.10 183 310 5.2E-10 T 28-03-2018 SmaCSM2_RS09285 00a018e7ef42fae2d1353f0156827df7 324 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 79 304 9.6E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS09285 00a018e7ef42fae2d1353f0156827df7 324 Gene3D G3DSA:3.40.190.10 71 182 8.2E-19 T 28-03-2018 SmaCSM2_RS09285 00a018e7ef42fae2d1353f0156827df7 324 SMART SM00062 77 308 3.9E-21 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS10590 c309089afc1ba96bfcb5b5028957f376 229 Gene3D G3DSA:3.40.50.720 7 225 4.5E-13 T 28-03-2018 SmaCSM2_RS10590 c309089afc1ba96bfcb5b5028957f376 229 SUPERFAMILY SSF51735 7 203 1.98E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS13965 3dc1b3ff0fa41f5881e6246b98daf5f8 330 Gene3D G3DSA:3.20.20.100 3 298 2.4E-53 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS13965 3dc1b3ff0fa41f5881e6246b98daf5f8 330 Pfam PF00248 Aldo/keto reductase family 23 313 1.7E-37 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS13965 3dc1b3ff0fa41f5881e6246b98daf5f8 330 Gene3D G3DSA:1.10.287.100 299 322 9.2E-4 T 28-03-2018 SmaCSM2_RS13965 3dc1b3ff0fa41f5881e6246b98daf5f8 330 SUPERFAMILY SSF51430 10 320 2.1E-59 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 SMART SM00650 30 201 1.4E-79 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 Gene3D G3DSA:1.10.8.100 212 266 4.3E-21 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 Gene3D G3DSA:3.40.50.150 12 211 2.3E-53 T 28-03-2018 SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 SUPERFAMILY SSF53335 22 266 1.04E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 16 266 1.7E-84 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 55.131 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 Pfam PF00398 Ribosomal RNA adenine dimethylase 16 265 2.7E-65 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SmaCSM2_RS03555 794d92c46922391e11061d03cf40da09 267 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 Pfam PF07660 Secretin and TonB N terminus short domain 60 109 4.0E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 SUPERFAMILY SSF56935 378 602 7.33E-69 T 28-03-2018 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 SUPERFAMILY SSF56935 152 346 7.33E-69 T 28-03-2018 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 SUPERFAMILY SSF56935 869 982 7.33E-69 T 28-03-2018 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 SUPERFAMILY SSF56935 698 837 7.33E-69 T 28-03-2018 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 Gene3D G3DSA:2.40.170.20 297 982 8.9E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 Pfam PF07715 TonB-dependent Receptor Plug Domain 149 254 4.7E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 Gene3D G3DSA:2.170.130.10 144 269 3.0E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 SMART SM00965 60 110 8.3E-10 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 SmaCSM2_RS12640 25f7c41f7601b6f1c124bd9ea8f3715c 982 Pfam PF00593 TonB dependent receptor 438 980 2.0E-27 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 Pfam PF00701 Dihydrodipicolinate synthetase family 3 289 1.4E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 PIRSF PIRSF001365 1 296 1.8E-55 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 8.2E-9 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 8.2E-9 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 8.2E-9 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 Gene3D G3DSA:3.20.20.70 1 296 5.1E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 SUPERFAMILY SSF51569 1 294 1.03E-65 T 28-03-2018 SmaCSM2_RS09390 0f67ab519b76c15eb619affd455164cc 296 SMART SM01130 1 294 2.2E-60 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SmaCSM2_RS11335 4c8338d2ec40bdac66827b24a56f0657 258 Gene3D G3DSA:1.10.3720.10 8 249 5.3E-24 T 28-03-2018 SmaCSM2_RS11335 4c8338d2ec40bdac66827b24a56f0657 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 245 3.6E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS11335 4c8338d2ec40bdac66827b24a56f0657 258 SUPERFAMILY SSF161098 53 238 2.35E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS21050 9548842100ccdbfe745fe219029c71e2 86 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 5 74 3.0E-16 T 28-03-2018 IPR027354 YcgL domain SmaCSM2_RS21050 9548842100ccdbfe745fe219029c71e2 86 SUPERFAMILY SSF160191 1 85 1.44E-28 T 28-03-2018 SmaCSM2_RS21050 9548842100ccdbfe745fe219029c71e2 86 Hamap MF_01866 Protein YcgL [ycgL]. 1 85 22.618 T 28-03-2018 IPR027354 YcgL domain SmaCSM2_RS21050 9548842100ccdbfe745fe219029c71e2 86 Pfam PF05166 YcgL domain 4 75 2.4E-27 T 28-03-2018 IPR027354 YcgL domain SmaCSM2_RS10770 a00f8b4f709856ada61308568093c057 152 Gene3D G3DSA:3.90.190.10 3 150 1.1E-22 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS10770 a00f8b4f709856ada61308568093c057 152 Pfam PF05706 Cyclin-dependent kinase inhibitor 3 (CDKN3) 7 113 6.9E-9 T 28-03-2018 IPR022778 CDKN3 domain GO:0004721|GO:0004725 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SmaCSM2_RS10770 a00f8b4f709856ada61308568093c057 152 SMART SM00404 46 146 1.4E-5 T 28-03-2018 IPR003595 Protein-tyrosine phosphatase, catalytic SmaCSM2_RS10770 a00f8b4f709856ada61308568093c057 152 SUPERFAMILY SSF52799 3 147 1.77E-33 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS16230 2cca332631fe87f52bdb684090d0ae3f 275 Gene3D G3DSA:3.40.50.300 8 275 1.9E-47 T 28-03-2018 SmaCSM2_RS16230 2cca332631fe87f52bdb684090d0ae3f 275 SUPERFAMILY SSF52540 184 221 1.07E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16230 2cca332631fe87f52bdb684090d0ae3f 275 SUPERFAMILY SSF52540 18 157 1.07E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.9E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.9E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.9E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.9E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.9E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 Gene3D G3DSA:3.40.50.720 4 279 2.6E-64 T 28-03-2018 SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 Pfam PF00106 short chain dehydrogenase 7 189 2.9E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 SUPERFAMILY SSF51735 6 245 8.32E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09215 c7dcc077b554add97c576680b06345f8 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 Gene3D G3DSA:3.40.720.10 22 516 1.2E-86 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 Pfam PF00245 Alkaline phosphatase 41 212 1.0E-19 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 Pfam PF00245 Alkaline phosphatase 325 434 2.9E-13 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 SMART SM00098 41 516 3.2E-8 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 SUPERFAMILY SSF53649 131 513 2.29E-71 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS19285 e53ec62a1033f8c197780ca0007551a6 517 SUPERFAMILY SSF53649 32 90 2.29E-71 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS07165 5a017da1716cf535ac5af1ed4e551ce6 333 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 77 293 1.8E-102 T 28-03-2018 IPR019262 Domain of unknown function DUF2272 SmaCSM2_RS07165 5a017da1716cf535ac5af1ed4e551ce6 333 PIRSF PIRSF028415 2 333 6.9E-136 T 28-03-2018 IPR014545 Uncharacterised conserved protein UCP028415 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 Pfam PF03466 LysR substrate binding domain 89 290 2.3E-42 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 SUPERFAMILY SSF46785 1 111 1.94E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 Gene3D G3DSA:1.10.10.10 1 83 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 Gene3D G3DSA:3.40.190.10 175 264 5.4E-25 T 28-03-2018 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 Gene3D G3DSA:3.40.190.10 91 174 7.1E-9 T 28-03-2018 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 SUPERFAMILY SSF53850 89 291 1.41E-44 T 28-03-2018 SmaCSM2_RS03675 0820b18a5539231da005befe97269bb1 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 Gene3D G3DSA:2.40.170.20 170 907 7.5E-63 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 Pfam PF00593 TonB dependent receptor 386 904 6.3E-44 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 Gene3D G3DSA:2.170.130.10 26 169 2.6E-33 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 SUPERFAMILY SSF56935 35 233 7.02E-96 T 28-03-2018 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 SUPERFAMILY SSF56935 276 324 7.02E-96 T 28-03-2018 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 SUPERFAMILY SSF56935 381 442 7.02E-96 T 28-03-2018 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 SUPERFAMILY SSF56935 717 907 7.02E-96 T 28-03-2018 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 SUPERFAMILY SSF56935 477 686 7.02E-96 T 28-03-2018 SmaCSM2_RS03880 03e05d0610d156f8ce0947a165ce7d00 912 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 168 1.8E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 SMART SM00422 4 72 3.8E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 SUPERFAMILY SSF46955 5 124 1.04E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 Gene3D G3DSA:1.10.1660.10 2 58 1.6E-16 T 28-03-2018 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 Gene3D G3DSA:1.10.1660.10 59 133 3.9E-8 T 28-03-2018 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 6.7E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 6.7E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 6.7E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS12680 0e0173759764a7d7026f1903cdc56569 135 Pfam PF13411 MerR HTH family regulatory protein 6 66 7.8E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS02875 d6bbd0589b124633b30d0adedc85e705 165 Pfam PF00583 Acetyltransferase (GNAT) family 34 128 3.4E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS02875 d6bbd0589b124633b30d0adedc85e705 165 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 19 150 9.8E-39 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 SmaCSM2_RS02875 d6bbd0589b124633b30d0adedc85e705 165 SUPERFAMILY SSF55729 10 153 1.42E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS02875 d6bbd0589b124633b30d0adedc85e705 165 Gene3D G3DSA:3.40.630.30 10 161 1.1E-35 T 28-03-2018 SmaCSM2_RS06205 ebefa1e2a8995145469de5a92ba18b67 70 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 58 7.2E-26 T 28-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system SmaCSM2_RS06205 ebefa1e2a8995145469de5a92ba18b67 70 Gene3D G3DSA:1.10.1220.10 4 35 9.6E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SmaCSM2_RS03945 d6e5e429eafe55645996ae8f2b27d0c2 178 Pfam PF00466 Ribosomal protein L10 6 101 1.6E-21 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SmaCSM2_RS03945 d6e5e429eafe55645996ae8f2b27d0c2 178 SUPERFAMILY SSF160369 4 160 2.88E-42 T 28-03-2018 SmaCSM2_RS03945 d6e5e429eafe55645996ae8f2b27d0c2 178 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 24.959 T 28-03-2018 IPR022973 Ribosomal protein L10 SmaCSM2_RS12790 a8b634658fe3de1933e49b802706e7ad 427 Pfam PF13372 Alginate export 33 419 1.9E-103 T 28-03-2018 IPR025388 Alginate export domain SmaCSM2_RS12790 a8b634658fe3de1933e49b802706e7ad 427 Gene3D G3DSA:2.40.160.10 27 403 8.8E-5 T 28-03-2018 SmaCSM2_RS12265 945e509392168482f0f8a825b7f6c635 404 SUPERFAMILY SSF102114 17 398 2.86E-34 T 28-03-2018 SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 Gene3D G3DSA:3.30.700.10 21 147 1.0E-13 T 28-03-2018 SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 SUPERFAMILY SSF54523 21 153 3.24E-16 T 28-03-2018 SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 Pfam PF00114 Pilin (bacterial filament) 49 155 2.5E-10 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 41 2.2E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS14920 02c2ed8003d6a20fe4f38e32f2b229c2 160 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 40 4.6E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 Gene3D G3DSA:3.40.50.1400 173 299 5.7E-39 T 28-03-2018 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 SUPERFAMILY SSF53800 5 319 1.57E-95 T 28-03-2018 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 Gene3D G3DSA:3.40.50.1400 2 172 3.5E-45 T 28-03-2018 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 Pfam PF00762 Ferrochelatase 7 318 4.7E-100 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 TIGRFAM TIGR00109 hemH: ferrochelatase 6 317 3.9E-91 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 Hamap MF_00323 Ferrochelatase [hemH]. 5 319 34.944 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SmaCSM2_RS21475 1bbe68af6991b55660863314a28ab4a6 320 ProSitePatterns PS00534 Ferrochelatase signature. 189 207 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SmaCSM2_RS12045 c2a377654c0c26170d21f4c9932e1852 318 Pfam PF16220 Domain of unknown function (DUF4880) 12 53 1.8E-11 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS12045 c2a377654c0c26170d21f4c9932e1852 318 PIRSF PIRSF018266 1 317 7.1E-64 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS12045 c2a377654c0c26170d21f4c9932e1852 318 Pfam PF04773 FecR protein 122 204 4.4E-15 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 101 1.0E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 2 170 7.6E-25 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 124 1.5E-10 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 Gene3D G3DSA:1.20.5.810 11 42 2.0E-10 T 28-03-2018 SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 Gene3D G3DSA:1.20.1290.10 43 175 7.1E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS11850 83f7a3d2a856f2edf9874fcfee61f27f 178 SUPERFAMILY SSF69118 1 174 2.3E-50 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 SUPERFAMILY SSF48452 360 495 7.74E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 Gene3D G3DSA:3.30.2010.10 59 143 2.4E-17 T 28-03-2018 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 Pfam PF01435 Peptidase family M48 63 259 3.3E-39 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 3 538 36.128 T 28-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 Gene3D G3DSA:1.25.20.10 315 544 1.6E-12 T 28-03-2018 SmaCSM2_RS04335 18def7c6541e7c5d982f8a85b34a6d2e 548 Pfam PF14559 Tetratricopeptide repeat 406 467 1.8E-6 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Pfam PF13089 Polyphosphate kinase N-terminal domain 24 128 1.1E-31 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 PIRSF PIRSF015589 9 695 4.4E-267 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Gene3D G3DSA:3.30.870.10 514 695 3.2E-34 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Pfam PF13090 Polyphosphate kinase C-terminal domain 344 692 5.5E-151 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 SUPERFAMILY SSF56024 329 510 4.08E-57 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Gene3D G3DSA:3.30.870.10 333 513 2.8E-24 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Gene3D G3DSA:3.30.1840.10 128 323 2.2E-60 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Gene3D G3DSA:1.20.58.310 26 127 2.2E-32 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Hamap MF_00347 Polyphosphate kinase [ppk]. 22 693 28.787 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 SUPERFAMILY SSF143724 127 330 2.35E-61 T 28-03-2018 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 Pfam PF02503 Polyphosphate kinase middle domain 138 337 7.5E-61 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 24 693 1.1E-280 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 SUPERFAMILY SSF140356 21 121 1.11E-34 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SmaCSM2_RS04320 bc8bba63e6691f1c5b62ad1afba64526 695 SUPERFAMILY SSF56024 514 693 2.69E-70 T 28-03-2018 SmaCSM2_RS18945 3b51ec61709d286bfebcc447b81d4976 130 Pfam PF07681 DoxX 10 89 1.1E-18 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 3.0E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 Gene3D G3DSA:1.10.10.60 1 79 2.2E-21 T 28-03-2018 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 163 217 4.4E-13 T 28-03-2018 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 8.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 8.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 Gene3D G3DSA:1.10.357.10 80 226 4.4E-24 T 28-03-2018 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 SUPERFAMILY SSF46689 22 103 4.99E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS17805 ff5bf90c493fa55cd2337d5252ae0b2d 226 SUPERFAMILY SSF48498 98 218 1.71E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS17475 ccb1a40b7f67b2445e4bdb50b4b5f807 182 SUPERFAMILY SSF101327 5 169 5.75E-29 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 SmaCSM2_RS17475 ccb1a40b7f67b2445e4bdb50b4b5f807 182 Pfam PF03695 Uncharacterised protein family (UPF0149) 17 168 7.5E-24 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Gene3D G3DSA:1.10.1670.10 135 230 4.2E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 SUPERFAMILY SSF48150 20 226 9.26E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 SMART SM00478 55 202 1.7E-55 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Gene3D G3DSA:1.10.340.30 21 134 5.3E-22 T 28-03-2018 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Pfam PF00633 Helix-hairpin-helix motif 116 144 5.2E-9 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 PIRSF PIRSF001435 17 229 9.8E-50 T 28-03-2018 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 TIGRFAM TIGR01083 nth: endonuclease III 22 211 1.2E-84 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 204 220 2.3E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 ProSitePatterns PS01155 Endonuclease III family signature. 119 148 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Hamap MF_00942 Endonuclease III [nth]. 11 226 36.948 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SmaCSM2_RS06910 92c3ac13e7dfb426b623177e856a2081 230 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 51 184 4.5E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SmaCSM2_RS16580 271f99521bbc0a9c95928d1c5236635e 170 SUPERFAMILY SSF55729 3 167 2.16E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS16580 271f99521bbc0a9c95928d1c5236635e 170 Pfam PF00583 Acetyltransferase (GNAT) family 29 146 2.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS16580 271f99521bbc0a9c95928d1c5236635e 170 Gene3D G3DSA:3.40.630.30 1 170 1.7E-30 T 28-03-2018 SmaCSM2_RS18265 369bf4a18d58c005400f2dfcda69c0f2 161 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 130 9.5E-31 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS18265 369bf4a18d58c005400f2dfcda69c0f2 161 Gene3D G3DSA:3.30.70.560 1 154 9.7E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS18265 369bf4a18d58c005400f2dfcda69c0f2 161 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 130 1.4E-26 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS18265 369bf4a18d58c005400f2dfcda69c0f2 161 SUPERFAMILY SSF55083 1 149 5.62E-40 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SmaCSM2_RS00785 317b59525295696d1a26cf6d50ed2ab3 139 Gene3D G3DSA:3.30.1150.10 37 134 2.8E-5 T 28-03-2018 SmaCSM2_RS09745 3495fc94bfe96cb74e13a1750639372a 130 SUPERFAMILY SSF54427 11 117 8.77E-12 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS09745 3495fc94bfe96cb74e13a1750639372a 130 Pfam PF14534 Domain of unknown function (DUF4440) 15 116 4.9E-7 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SmaCSM2_RS09745 3495fc94bfe96cb74e13a1750639372a 130 Gene3D G3DSA:3.10.450.50 8 117 1.0E-6 T 28-03-2018 SmaCSM2_RS08095 8409ce521e5c54f45550d98a991da9ee 210 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 13 206 28.078 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 SmaCSM2_RS08095 8409ce521e5c54f45550d98a991da9ee 210 Gene3D G3DSA:3.40.50.150 1 210 1.6E-53 T 28-03-2018 SmaCSM2_RS08095 8409ce521e5c54f45550d98a991da9ee 210 Pfam PF01728 FtsJ-like methyltransferase 30 204 3.2E-49 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SmaCSM2_RS08095 8409ce521e5c54f45550d98a991da9ee 210 SUPERFAMILY SSF53335 28 205 7.5E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS08095 8409ce521e5c54f45550d98a991da9ee 210 PIRSF PIRSF005461 1 210 5.2E-72 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 232 241 3.5E-10 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 345 358 3.5E-10 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 260 271 3.5E-10 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 190 204 7.7E-38 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 260 276 7.7E-38 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 229 243 7.7E-38 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 277 294 7.7E-38 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 302 313 7.7E-38 T 28-03-2018 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 SUPERFAMILY SSF52317 153 372 1.78E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 371 4.2E-145 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 131 4.7E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 SUPERFAMILY SSF52021 4 149 8.24E-57 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 Gene3D G3DSA:3.40.50.880 151 375 5.1E-63 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 374 48.121 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 Pfam PF00117 Glutamine amidotransferase class-I 193 367 3.6E-45 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 SMART SM01097 3 133 9.2E-89 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS09825 949b1f25b151295f19a42ec6fba800e8 375 Gene3D G3DSA:3.50.30.20 2 150 2.2E-62 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SmaCSM2_RS06975 957b7e53986b45fecb9c585616845a70 292 Gene3D G3DSA:1.20.5.170 209 292 5.3E-4 T 28-03-2018 SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 2.3E-57 T 28-03-2018 SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.0E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 SUPERFAMILY SSF51735 9 246 1.43E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 1.8E-6 T 28-03-2018 SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 Gene3D G3DSA:3.40.50.720 2 247 8.9E-70 T 28-03-2018 SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11940 40002e801f59cf3de5c671bd12e295b4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11770 00cd66b43ed5abba7bc0502aebdcf828 130 Pfam PF11528 Protein of unknown function (DUF3224) 7 124 3.5E-35 T 28-03-2018 IPR021607 Protein of unknown function DUF3224 SmaCSM2_RS11770 00cd66b43ed5abba7bc0502aebdcf828 130 Gene3D G3DSA:2.40.350.10 2 130 1.5E-36 T 28-03-2018 IPR023159 SO1590-like domain SmaCSM2_RS11770 00cd66b43ed5abba7bc0502aebdcf828 130 SUPERFAMILY SSF159238 2 127 6.8E-39 T 28-03-2018 IPR023159 SO1590-like domain SmaCSM2_RS17010 1214ca2808f20f97cab5fd0cd7484b16 198 Pfam PF12840 Helix-turn-helix domain 20 76 1.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17010 1214ca2808f20f97cab5fd0cd7484b16 198 SMART SM00418 20 126 1.2E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SmaCSM2_RS17010 1214ca2808f20f97cab5fd0cd7484b16 198 SUPERFAMILY SSF46785 18 92 2.25E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17010 1214ca2808f20f97cab5fd0cd7484b16 198 Gene3D G3DSA:1.10.10.10 13 95 9.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 63 172 4.2E-23 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 177 41.309 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 37 177 1.7E-76 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 Gene3D G3DSA:3.40.50.700 36 182 1.8E-48 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 SUPERFAMILY SSF56770 35 179 4.97E-66 T 28-03-2018 SmaCSM2_RS15170 8860ca72117fdc605e57a302b9351014 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 144 160 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS01040 65dd352a72e7fed174749bd7f47ef820 536 Gene3D G3DSA:3.90.226.10 275 532 1.9E-73 T 28-03-2018 SmaCSM2_RS01040 65dd352a72e7fed174749bd7f47ef820 536 Pfam PF01039 Carboxyl transferase domain 48 524 3.0E-154 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SmaCSM2_RS01040 65dd352a72e7fed174749bd7f47ef820 536 SUPERFAMILY SSF52096 23 273 9.66E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01040 65dd352a72e7fed174749bd7f47ef820 536 Gene3D G3DSA:3.90.226.10 9 274 3.9E-70 T 28-03-2018 SmaCSM2_RS01040 65dd352a72e7fed174749bd7f47ef820 536 SUPERFAMILY SSF52096 237 518 1.88E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS15495 b933112de91c765bd2e337b7714093e6 179 Pfam PF00877 NlpC/P60 family 69 176 2.2E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SmaCSM2_RS15495 b933112de91c765bd2e337b7714093e6 179 Gene3D G3DSA:2.30.260.10 103 179 1.1E-20 T 28-03-2018 SmaCSM2_RS15495 b933112de91c765bd2e337b7714093e6 179 Gene3D G3DSA:3.90.1720.10 32 102 3.4E-16 T 28-03-2018 SmaCSM2_RS15495 b933112de91c765bd2e337b7714093e6 179 SUPERFAMILY SSF54001 49 178 3.92E-42 T 28-03-2018 SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 SUPERFAMILY SSF56935 29 772 8.06E-59 T 28-03-2018 SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 Gene3D G3DSA:2.170.130.10 58 180 6.1E-7 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 Pfam PF00593 TonB dependent receptor 323 768 6.6E-29 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 755 772 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 167 1.0E-5 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS20365 58f18b02047dc58b9c2205e0ee260c1d 772 Gene3D G3DSA:2.40.170.20 181 772 1.6E-47 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 SUPERFAMILY SSF101386 151 254 4.74E-26 T 28-03-2018 SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 TIGRFAM TIGR00444 mazG: MazG family protein 23 274 3.4E-94 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 Gene3D G3DSA:1.10.287.1080 152 279 4.7E-29 T 28-03-2018 SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 SUPERFAMILY SSF101386 15 118 8.41E-26 T 28-03-2018 SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 Gene3D G3DSA:1.10.287.1080 16 135 9.6E-42 T 28-03-2018 SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 40 113 1.4E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SmaCSM2_RS16440 f0b5ee79bc250465bbb88725860fcf06 279 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 182 243 5.5E-9 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 SUPERFAMILY SSF52374 7 258 7.24E-80 T 28-03-2018 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 111 1.2E-22 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 127 231 1.2E-17 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 Gene3D G3DSA:3.40.50.620 126 221 2.5E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 6 289 38.785 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 5.0E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 5.0E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 193 5.0E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 5.0E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 169 179 5.0E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 7 267 1.3E-100 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 SmaCSM2_RS14730 42286579ed021975a5478fa5e90b776a 306 Gene3D G3DSA:3.40.50.620 2 125 1.7E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS11285 4c288cfaec72a335eccbaf6bb765f665 309 Pfam PF05368 NmrA-like family 10 242 3.9E-17 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SmaCSM2_RS11285 4c288cfaec72a335eccbaf6bb765f665 309 Gene3D G3DSA:3.40.50.720 3 120 2.5E-8 T 28-03-2018 SmaCSM2_RS11285 4c288cfaec72a335eccbaf6bb765f665 309 SUPERFAMILY SSF51735 8 259 5.83E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS11285 4c288cfaec72a335eccbaf6bb765f665 309 Gene3D G3DSA:3.90.25.10 160 295 3.9E-8 T 28-03-2018 SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 301 1.2E-62 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 Gene3D G3DSA:3.40.50.1100 19 137 1.7E-35 T 28-03-2018 SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 SUPERFAMILY SSF53686 3 321 2.36E-88 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 Pfam PF00571 CBS domain 342 388 2.1E-5 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 SMART SM00116 343 390 1.1E-6 T 28-03-2018 IPR000644 CBS domain SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 Gene3D G3DSA:3.10.580.10 327 456 2.1E-17 T 28-03-2018 SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 Gene3D G3DSA:3.40.50.1100 138 322 1.8E-45 T 28-03-2018 SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SmaCSM2_RS02660 bd7fc3ac059b6b2dfb0515dca517b543 456 SUPERFAMILY SSF54631 336 452 6.44E-17 T 28-03-2018 SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 SUPERFAMILY SSF54211 133 277 8.34E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 291 1.4E-116 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.4E-104 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 Gene3D G3DSA:3.30.1700.10 128 299 9.9E-63 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 Gene3D G3DSA:3.30.230.20 1 127 3.5E-49 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 SUPERFAMILY SSF54211 3 125 1.59E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS03290 1205db76b7aa2da38cfdf46eb9fb56b4 303 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 45.707 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SmaCSM2_RS09450 4c189f81fad73d19ceebc098ab7f9292 191 Pfam PF01339 CheB methylesterase 11 185 1.7E-52 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09450 4c189f81fad73d19ceebc098ab7f9292 191 SUPERFAMILY SSF52738 5 189 7.98E-52 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS09450 4c189f81fad73d19ceebc098ab7f9292 191 Gene3D G3DSA:3.40.50.180 2 191 3.8E-63 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SmaCSM2_RS17825 1bc7b3f644b771f0eb3f4d2accadf4d4 432 Gene3D G3DSA:3.40.50.2000 239 411 1.7E-15 T 28-03-2018 SmaCSM2_RS17825 1bc7b3f644b771f0eb3f4d2accadf4d4 432 Gene3D G3DSA:3.40.50.2300 163 238 0.53 T 28-03-2018 SmaCSM2_RS17825 1bc7b3f644b771f0eb3f4d2accadf4d4 432 SUPERFAMILY SSF53756 58 407 6.15E-17 T 28-03-2018 SmaCSM2_RS17825 1bc7b3f644b771f0eb3f4d2accadf4d4 432 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 42 219 7.5E-65 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 SmaCSM2_RS09775 6276bd4492c046eb6591376eabb921d6 133 Gene3D G3DSA:3.10.180.10 1 133 1.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS09775 6276bd4492c046eb6591376eabb921d6 133 SUPERFAMILY SSF54593 2 127 5.78E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS09775 6276bd4492c046eb6591376eabb921d6 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 121 8.8E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 SMART SM00487 58 259 2.4E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Gene3D G3DSA:3.40.50.300 253 426 6.1E-46 T 28-03-2018 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 SMART SM00490 306 406 1.8E-14 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 SUPERFAMILY SSF52540 73 586 1.14E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 689 763 8.8E-12 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 18 615 1.8E-275 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Pfam PF11898 Domain of unknown function (DUF3418) 779 1355 3.3E-175 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Pfam PF00270 DEAD/DEAH box helicase 85 233 5.4E-8 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Pfam PF00271 Helicase conserved C-terminal domain 287 405 2.8E-11 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Gene3D G3DSA:3.40.50.300 76 235 4.7E-32 T 28-03-2018 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 Pfam PF04408 Helicase associated domain (HA2) 469 547 1.5E-15 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 SMART SM00382 92 372 6.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS16550 3b936391eadcd2af57ba5fefa7400061 1360 SMART SM00847 466 556 1.9E-31 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 84 97 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 21 289 3.0E-123 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 PIRSF PIRSF000770 12 291 1.8E-33 T 28-03-2018 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 55 286 3.1E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 SUPERFAMILY SSF88659 214 288 6.73E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Gene3D G3DSA:1.10.10.10 229 290 7.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 8 291 52.079 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Pfam PF00140 Sigma-70 factor, region 1.2 22 53 2.0E-5 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Pfam PF04545 Sigma-70, region 4 236 286 2.0E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 SUPERFAMILY SSF88946 22 129 8.5E-38 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 259 285 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 PRINTS PR00046 Major sigma-70 factor signature 84 97 2.0E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 PRINTS PR00046 Major sigma-70 factor signature 259 274 2.0E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 PRINTS PR00046 Major sigma-70 factor signature 239 251 2.0E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 PRINTS PR00046 Major sigma-70 factor signature 274 285 2.0E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Pfam PF04542 Sigma-70 region 2 60 129 2.4E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS19420 1e3a5664884b6344eeb51160f507c34d 291 Gene3D G3DSA:1.10.601.10 18 129 2.2E-34 T 28-03-2018 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 169 3.4E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 Gene3D G3DSA:2.40.170.20 175 879 8.6E-83 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 Gene3D G3DSA:2.170.130.10 47 174 3.7E-31 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 SUPERFAMILY SSF56935 395 879 7.94E-105 T 28-03-2018 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 SUPERFAMILY SSF56935 308 356 7.94E-105 T 28-03-2018 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 SUPERFAMILY SSF56935 39 249 7.94E-105 T 28-03-2018 SmaCSM2_RS02595 44c4b1867380d4f7a81172a826380ff4 879 Pfam PF00593 TonB dependent receptor 397 878 7.2E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05350 00bf0941b63bfa1ae92d6a9490eba700 102 Pfam PF12977 Domain of Unknown Function with PDB structure (DUF3861) 7 76 3.0E-10 T 28-03-2018 IPR024476 Protein of unknown function DUF3861 SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 SUPERFAMILY SSF46785 5 111 9.87E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 SUPERFAMILY SSF53850 91 292 2.35E-35 T 28-03-2018 SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 Gene3D G3DSA:3.40.190.10 83 173 2.1E-17 T 28-03-2018 SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 Gene3D G3DSA:1.10.10.10 3 82 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 Gene3D G3DSA:3.40.190.10 174 254 1.1E-12 T 28-03-2018 SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 7.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS19275 2aa3129025fbba2748828688a4c43ec4 299 Pfam PF03466 LysR substrate binding domain 88 287 7.6E-30 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 Pfam PF00117 Glutamine amidotransferase class-I 4 190 3.2E-55 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 192 1.0E-77 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.0E-13 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.0E-13 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.0E-13 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 Gene3D G3DSA:3.40.50.880 1 194 1.1E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.2E-35 T 28-03-2018 SmaCSM2_RS19700 5b13e25a3ba4513f05dd972ccce1b5b0 195 SUPERFAMILY SSF52317 1 191 3.67E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 SUPERFAMILY SSF100950 231 503 9.42E-82 T 28-03-2018 SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 12 502 1.1E-237 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 SUPERFAMILY SSF100950 4 228 1.15E-73 T 28-03-2018 SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 Gene3D G3DSA:3.40.1080.10 13 225 1.7E-37 T 28-03-2018 SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 14 221 7.7E-33 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 327 469 2.5E-42 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain SmaCSM2_RS01985 cebe855f08909729a3ae0baf29589348 504 Gene3D G3DSA:3.40.1080.10 236 503 1.0E-57 T 28-03-2018 SmaCSM2_RS12175 815a3c82edf7605019c7c8614d6ee005 387 Pfam PF12693 GspL periplasmic domain 240 372 3.6E-10 T 28-03-2018 IPR025691 GspL periplasmic domain SmaCSM2_RS12175 815a3c82edf7605019c7c8614d6ee005 387 SUPERFAMILY SSF53067 5 143 2.59E-16 T 28-03-2018 SmaCSM2_RS12175 815a3c82edf7605019c7c8614d6ee005 387 Pfam PF05134 Type II secretion system (T2SS), protein L 7 172 2.4E-10 T 28-03-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain SmaCSM2_RS19295 47b8656db64cb2955478212703b2d8e5 197 Gene3D G3DSA:1.10.357.10 4 197 4.7E-23 T 28-03-2018 SmaCSM2_RS19295 47b8656db64cb2955478212703b2d8e5 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS19295 47b8656db64cb2955478212703b2d8e5 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS19295 47b8656db64cb2955478212703b2d8e5 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS19295 47b8656db64cb2955478212703b2d8e5 197 SUPERFAMILY SSF46689 9 76 1.44E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS02155 ce8fa36836d45570b3fdc654ffdc55f7 322 SUPERFAMILY SSF88713 215 273 1.7E-27 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS02155 ce8fa36836d45570b3fdc654ffdc55f7 322 SUPERFAMILY SSF88713 23 181 1.7E-27 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SmaCSM2_RS02155 ce8fa36836d45570b3fdc654ffdc55f7 322 Pfam PF01522 Polysaccharide deacetylase 23 150 8.2E-11 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SmaCSM2_RS02155 ce8fa36836d45570b3fdc654ffdc55f7 322 Gene3D G3DSA:3.20.20.370 14 277 2.7E-26 T 28-03-2018 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 180 277 3.0E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 27 129 4.4E-20 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 30 280 2.1E-68 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 Gene3D G3DSA:2.160.20.70 160 281 3.2E-31 T 28-03-2018 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 29 281 25.847 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 SmaCSM2_RS05775 c8387e35f7f475fef10ea7ab2bdc2db0 281 SUPERFAMILY SSF63848 180 280 9.55E-29 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 SmaCSM2_RS00330 b8a613100bc77664eee94d156882e7cb 223 SUPERFAMILY SSF81901 57 116 9.68E-8 T 28-03-2018 SmaCSM2_RS00330 b8a613100bc77664eee94d156882e7cb 223 Gene3D G3DSA:2.60.40.1180 56 167 7.0E-8 T 28-03-2018 SmaCSM2_RS04565 67b0b8a1fae369dd112d04b75acfe48a 284 Pfam PF00482 Type II secretion system (T2SS), protein F 119 242 5.1E-17 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS21630 e28e680bb6538d083ac26db93c890475 262 Pfam PF00005 ABC transporter 24 171 2.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS21630 e28e680bb6538d083ac26db93c890475 262 Gene3D G3DSA:3.40.50.300 5 252 4.8E-61 T 28-03-2018 SmaCSM2_RS21630 e28e680bb6538d083ac26db93c890475 262 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS21630 e28e680bb6538d083ac26db93c890475 262 SUPERFAMILY SSF52540 8 234 3.82E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21630 e28e680bb6538d083ac26db93c890475 262 SMART SM00382 33 248 8.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS06175 e670195ef7eb20212398bbc404a60dd3 395 Pfam PF12698 ABC-2 family transporter protein 31 373 2.0E-33 T 28-03-2018 SmaCSM2_RS06175 e670195ef7eb20212398bbc404a60dd3 395 Gene3D G3DSA:3.40.1710.10 49 205 1.7E-21 T 28-03-2018 SmaCSM2_RS14795 a80d925b75cf08069fc3018c43f5238f 630 Gene3D G3DSA:1.25.40.10 62 140 0.074 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14795 a80d925b75cf08069fc3018c43f5238f 630 Gene3D G3DSA:3.90.1580.10 343 630 3.1E-66 T 28-03-2018 SmaCSM2_RS14795 a80d925b75cf08069fc3018c43f5238f 630 Gene3D G3DSA:1.25.40.10 142 312 1.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS14795 a80d925b75cf08069fc3018c43f5238f 630 Pfam PF03781 Sulfatase-modifying factor enzyme 1 354 628 1.9E-67 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SmaCSM2_RS14795 a80d925b75cf08069fc3018c43f5238f 630 SUPERFAMILY SSF56436 354 629 2.59E-63 T 28-03-2018 IPR016187 C-type lectin fold SmaCSM2_RS11410 960146cf6908f7f13545f225d151bce8 118 Pfam PF05901 Excalibur calcium-binding domain 77 112 7.5E-15 T 28-03-2018 IPR008613 Excalibur calcium-binding domain SmaCSM2_RS11410 960146cf6908f7f13545f225d151bce8 118 SMART SM00894 76 112 9.3E-20 T 28-03-2018 IPR008613 Excalibur calcium-binding domain SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 SMART SM00342 25 108 9.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 SUPERFAMILY SSF46689 61 111 5.02E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 SUPERFAMILY SSF46689 9 58 1.29E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 Gene3D G3DSA:1.10.10.60 63 122 1.1E-14 T 28-03-2018 SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 Gene3D G3DSA:1.10.10.60 6 62 3.1E-15 T 28-03-2018 SmaCSM2_RS11505 1fd8f7977ef892fa3c5a1465f6f20e2c 153 Pfam PF12833 Helix-turn-helix domain 31 110 5.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS15800 184a2b162437a5342a169cc1feab1b60 88 SUPERFAMILY SSF57716 38 72 2.0E-8 T 28-03-2018 SmaCSM2_RS15800 184a2b162437a5342a169cc1feab1b60 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 35 68 3.2E-13 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SmaCSM2_RS15800 184a2b162437a5342a169cc1feab1b60 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site SmaCSM2_RS15800 184a2b162437a5342a169cc1feab1b60 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 3.2E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SmaCSM2_RS15800 184a2b162437a5342a169cc1feab1b60 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 3.2E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SmaCSM2_RS18270 2c4c01e70e29bf558d904b3715857d0d 247 SUPERFAMILY SSF56235 2 243 2.04E-33 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS18270 2c4c01e70e29bf558d904b3715857d0d 247 Pfam PF00227 Proteasome subunit 4 186 1.7E-8 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SmaCSM2_RS18270 2c4c01e70e29bf558d904b3715857d0d 247 PIRSF PIRSF009120 1 247 6.7E-88 T 28-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 SmaCSM2_RS18270 2c4c01e70e29bf558d904b3715857d0d 247 Gene3D G3DSA:3.60.20.10 2 230 8.6E-37 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS03740 24b1bbc42bd981a365ba6a6003fc7c47 486 SUPERFAMILY SSF52467 307 480 2.71E-72 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS03740 24b1bbc42bd981a365ba6a6003fc7c47 486 Pfam PF02233 NAD(P) transhydrogenase beta subunit 14 477 2.3E-171 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 SmaCSM2_RS03740 24b1bbc42bd981a365ba6a6003fc7c47 486 Gene3D G3DSA:3.40.50.1220 306 480 4.2E-80 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS03740 24b1bbc42bd981a365ba6a6003fc7c47 486 PIRSF PIRSF000204 8 481 3.9E-162 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 SmaCSM2_RS01840 4da668e696aa97897020ea5efa393fdc 166 Gene3D G3DSA:3.90.190.10 17 159 4.0E-22 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS01840 4da668e696aa97897020ea5efa393fdc 166 SUPERFAMILY SSF52799 26 144 1.16E-18 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS01840 4da668e696aa97897020ea5efa393fdc 166 Pfam PF04273 Putative phosphatase (DUF442) 28 129 7.9E-16 T 28-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 Pfam PF03725 3' exoribonuclease family, domain 2 161 227 4.2E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 Gene3D G3DSA:3.30.230.70 2 241 7.3E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 Pfam PF01138 3' exoribonuclease family, domain 1 13 143 1.4E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 SUPERFAMILY SSF55666 156 239 6.28E-24 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 Hamap MF_00564 Ribonuclease PH [rph]. 4 240 49.462 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 5 239 3.6E-115 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 SUPERFAMILY SSF54211 3 184 8.6E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SmaCSM2_RS17435 66f50b7aa81504d99fdeeccabe126fce 241 ProSitePatterns PS01277 Ribonuclease PH signature. 119 132 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 7 235 4.2E-24 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 Hamap MF_01274 Type III pantothenate kinase [coaX]. 2 241 15.097 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 Gene3D G3DSA:3.30.420.40 80 242 3.0E-39 T 28-03-2018 SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 SUPERFAMILY SSF53067 5 110 4.66E-19 T 28-03-2018 SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 Pfam PF03309 Type III pantothenate kinase 5 193 3.7E-38 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SmaCSM2_RS01345 2c874d4979d776e2e037dc265a43bfff 243 SUPERFAMILY SSF53067 114 237 1.38E-24 T 28-03-2018 SmaCSM2_RS05335 2cbafa2861bec375f02b4ffb66a69dc5 180 Pfam PF01965 DJ-1/PfpI family 8 176 2.1E-51 T 28-03-2018 IPR002818 DJ-1/PfpI SmaCSM2_RS05335 2cbafa2861bec375f02b4ffb66a69dc5 180 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 178 2.9E-51 T 28-03-2018 IPR006286 Peptidase C56, PfpI SmaCSM2_RS05335 2cbafa2861bec375f02b4ffb66a69dc5 180 Gene3D G3DSA:3.40.50.880 1 180 7.5E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS05335 2cbafa2861bec375f02b4ffb66a69dc5 180 SUPERFAMILY SSF52317 7 178 2.64E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 SUPERFAMILY SSF51351 1 247 5.24E-87 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 40.417 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 238 1.1E-65 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 Pfam PF00121 Triosephosphate isomerase 4 244 4.2E-87 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SmaCSM2_RS15190 9cb3d1b1777f96536dfcd22b1cf7af2f 251 Gene3D G3DSA:3.20.20.70 1 251 3.2E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS02985 18ba56a56f3a8c6922b35475c1e363ec 210 SUPERFAMILY SSF54523 43 193 7.32E-5 T 28-03-2018 SmaCSM2_RS02985 18ba56a56f3a8c6922b35475c1e363ec 210 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02985 18ba56a56f3a8c6922b35475c1e363ec 210 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 28 1.2E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS19875 f174b3588328d38efb410847c8f196ca 701 SUPERFAMILY SSF53649 155 464 7.45E-42 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SmaCSM2_RS19875 f174b3588328d38efb410847c8f196ca 701 Pfam PF00884 Sulfatase 157 443 4.5E-24 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SmaCSM2_RS19875 f174b3588328d38efb410847c8f196ca 701 Gene3D G3DSA:3.40.720.10 147 445 1.3E-33 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SmaCSM2_RS07160 1a6774a437b8bf83d89ccb71b2bc42a6 116 Pfam PF11743 Protein of unknown function (DUF3301) 4 97 3.0E-30 T 28-03-2018 IPR021732 Protein of unknown function DUF3301 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 Pfam PF12852 Cupin 3 156 8.5E-29 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 SUPERFAMILY SSF51215 35 153 8.63E-5 T 28-03-2018 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 Gene3D G3DSA:1.10.10.60 169 226 6.4E-12 T 28-03-2018 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 SUPERFAMILY SSF46689 223 272 1.3E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 Pfam PF12833 Helix-turn-helix domain 193 270 1.9E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 Gene3D G3DSA:1.10.10.60 227 277 9.3E-13 T 28-03-2018 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 SMART SM00342 187 269 4.2E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 SUPERFAMILY SSF46689 170 221 4.48E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 Gene3D G3DSA:2.60.120.280 26 157 5.0E-10 T 28-03-2018 SmaCSM2_RS07870 407c6e38d54ae58249d27d98d7e3e7b4 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 265 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS01540 565a35802adc4a5841cee0cd224840a5 119 PIRSF PIRSF007028 1 117 1.3E-50 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 SmaCSM2_RS01540 565a35802adc4a5841cee0cd224840a5 119 Pfam PF07237 Protein of unknown function (DUF1428) 2 103 1.2E-45 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 SmaCSM2_RS01540 565a35802adc4a5841cee0cd224840a5 119 Gene3D G3DSA:3.30.70.100 1 117 2.8E-60 T 28-03-2018 SmaCSM2_RS01540 565a35802adc4a5841cee0cd224840a5 119 SUPERFAMILY SSF54909 1 116 1.07E-51 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 Pfam PF00376 MerR family regulatory protein 2 39 1.2E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 SMART SM00422 1 70 1.8E-30 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 Gene3D G3DSA:1.10.1660.10 57 136 1.5E-22 T 28-03-2018 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 Gene3D G3DSA:1.10.1660.10 1 56 6.8E-25 T 28-03-2018 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 Pfam PF09278 MerR, DNA binding 44 107 7.9E-21 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 SUPERFAMILY SSF46955 1 126 5.13E-39 T 28-03-2018 IPR009061 Putative DNA-binding domain SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS10955 e35650374387645daa7e487dcf6d8d7c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 202 218 0.017 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 225 259 4.7E-5 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 115 145 1.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Gene3D G3DSA:2.160.10.10 25 214 1.8E-27 T 28-03-2018 SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 SUPERFAMILY SSF51161 35 319 3.25E-77 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 26 91 7.2E-22 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Gene3D G3DSA:2.160.10.10 215 339 7.2E-19 T 28-03-2018 SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 10 331 1.1E-123 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 SmaCSM2_RS06600 194d7107825ec44822f7b9eff29aaf80 340 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 7 328 36.117 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 SmaCSM2_RS13055 6235ae34f7fba557a03bcfa780b89739 237 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 161 236 2.2E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS13055 6235ae34f7fba557a03bcfa780b89739 237 Gene3D G3DSA:3.30.1150.10 56 237 1.3E-18 T 28-03-2018 SmaCSM2_RS13055 6235ae34f7fba557a03bcfa780b89739 237 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 160 236 1.3E-18 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS13055 6235ae34f7fba557a03bcfa780b89739 237 SUPERFAMILY SSF74653 156 234 1.31E-15 T 28-03-2018 SmaCSM2_RS21635 eb6631b5dbb37368dfcd687d71756667 249 Pfam PF02405 Permease MlaE 35 245 2.2E-66 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 SmaCSM2_RS21635 eb6631b5dbb37368dfcd687d71756667 249 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 248 3.2E-72 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria SmaCSM2_RS12530 5d87735598e0904ca0a67ab35e79cb9a 159 Pfam PF13673 Acetyltransferase (GNAT) domain 28 146 3.0E-31 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS12530 5d87735598e0904ca0a67ab35e79cb9a 159 SUPERFAMILY SSF55729 2 139 2.06E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS12530 5d87735598e0904ca0a67ab35e79cb9a 159 Gene3D G3DSA:3.40.630.30 86 138 2.6E-8 T 28-03-2018 SmaCSM2_RS12530 5d87735598e0904ca0a67ab35e79cb9a 159 Gene3D G3DSA:3.40.630.30 2 85 2.0E-16 T 28-03-2018 SmaCSM2_RS01410 b8adf70cfe5d251007e4da8ca61f7bc3 310 Pfam PF00753 Metallo-beta-lactamase superfamily 21 209 1.7E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS01410 b8adf70cfe5d251007e4da8ca61f7bc3 310 SMART SM00849 19 224 2.6E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS01410 b8adf70cfe5d251007e4da8ca61f7bc3 310 SUPERFAMILY SSF56281 4 273 5.5E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS01410 b8adf70cfe5d251007e4da8ca61f7bc3 310 Gene3D G3DSA:3.60.15.10 2 260 2.4E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 Pfam PF00271 Helicase conserved C-terminal domain 585 695 1.7E-6 T 28-03-2018 IPR001650 Helicase, C-terminal SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 SUPERFAMILY SSF52540 571 736 6.53E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 SUPERFAMILY SSF52540 351 412 6.53E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 SUPERFAMILY SSF52540 68 180 1.29E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 SUPERFAMILY SSF52540 345 411 1.29E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 Gene3D G3DSA:3.40.50.300 572 732 3.8E-17 T 28-03-2018 SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 Gene3D G3DSA:3.40.50.10810 56 542 1.0E-24 T 28-03-2018 SmaCSM2_RS07655 d0b4207fb19f94a84236a921a8e7b8f5 759 SMART SM00487 69 413 1.5E-9 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 9.4E-51 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 SUPERFAMILY SSF46946 2 114 1.16E-43 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 PIRSF PIRSF002134 1 118 1.6E-41 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 6.9E-30 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 Gene3D G3DSA:1.10.8.50 1 66 3.7E-20 T 28-03-2018 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 Gene3D G3DSA:4.10.910.10 67 84 1.7E-15 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 Gene3D G3DSA:4.10.910.10 85 118 4.8E-24 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS04095 efad6bda9b44b84e9cbf49356964d871 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.527 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 167 231 1.7E-21 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 PIRSF PIRSF006487 16 126 1.3E-4 T 28-03-2018 SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 PIRSF PIRSF006487 152 275 0.37 T 28-03-2018 SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 SUPERFAMILY SSF103025 11 222 2.04E-42 T 28-03-2018 SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 Pfam PF01571 Aminomethyltransferase folate-binding domain 22 105 1.7E-5 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 Gene3D G3DSA:3.30.70.1400 18 219 1.6E-24 T 28-03-2018 SmaCSM2_RS08425 d09d1aa371f1099b47ef17adb9f1abec 291 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 206 275 8.5E-6 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 10 294 9.4E-123 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 SUPERFAMILY SSF51621 10 293 2.96E-100 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 Pfam PF13714 Phosphoenolpyruvate phosphomutase 14 257 5.7E-50 T 28-03-2018 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 7 295 48.147 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SmaCSM2_RS16205 1b8271ff1a233ae3b7b5af888404dc59 297 Gene3D G3DSA:3.20.20.60 7 297 6.0E-89 T 28-03-2018 SmaCSM2_RS09695 dc698ba35e64125549d4286e4d112eee 204 SUPERFAMILY SSF55811 70 203 3.36E-16 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS09695 dc698ba35e64125549d4286e4d112eee 204 Pfam PF00293 NUDIX domain 71 192 1.5E-8 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS09695 dc698ba35e64125549d4286e4d112eee 204 Gene3D G3DSA:3.90.79.10 65 204 1.8E-17 T 28-03-2018 SmaCSM2_RS11055 cd3c0e0c30764d3ad6bb4abfe215879d 266 SUPERFAMILY SSF52402 4 168 9.7E-24 T 28-03-2018 SmaCSM2_RS11055 cd3c0e0c30764d3ad6bb4abfe215879d 266 Gene3D G3DSA:3.40.50.620 2 259 1.3E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS11055 cd3c0e0c30764d3ad6bb4abfe215879d 266 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 6 122 5.4E-12 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 Pfam PF12833 Helix-turn-helix domain 313 390 1.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 Gene3D G3DSA:1.10.10.10 318 346 0.023 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 Gene3D G3DSA:1.10.10.60 347 392 5.6E-14 T 28-03-2018 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 Gene3D G3DSA:1.10.10.10 258 317 0.033 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 358 373 2.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 373 389 2.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 SMART SM00342 307 389 1.3E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 81 264 8.4E-42 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal SmaCSM2_RS11220 62307628b87ee32017f469f89e18d74d 392 SUPERFAMILY SSF46689 343 391 2.82E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS14940 c8ff80bc74584c30c14e3298b43f340e 77 Gene3D G3DSA:2.30.30.320 9 77 7.0E-26 T 28-03-2018 IPR023387 DUF1653-like domain SmaCSM2_RS14940 c8ff80bc74584c30c14e3298b43f340e 77 Pfam PF07866 Protein of unknown function (DUF1653) 14 73 3.2E-26 T 28-03-2018 IPR023387 DUF1653-like domain SmaCSM2_RS08545 c8c4034683b9a4ad5a601a027fcea805 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 20 155 2.0E-30 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SmaCSM2_RS08545 c8c4034683b9a4ad5a601a027fcea805 159 Gene3D G3DSA:3.30.530.20 5 159 3.3E-29 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS08545 c8c4034683b9a4ad5a601a027fcea805 159 SUPERFAMILY SSF55961 8 158 8.46E-48 T 28-03-2018 SmaCSM2_RS16055 2a74cd26afe02fedaee037d9bb1f94dc 298 SUPERFAMILY SSF63380 8 129 1.5E-10 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS16055 2a74cd26afe02fedaee037d9bb1f94dc 298 Gene3D G3DSA:3.40.50.80 141 297 1.2E-39 T 28-03-2018 SmaCSM2_RS16055 2a74cd26afe02fedaee037d9bb1f94dc 298 Pfam PF08021 Siderophore-interacting FAD-binding domain 15 130 1.1E-41 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SmaCSM2_RS16055 2a74cd26afe02fedaee037d9bb1f94dc 298 Pfam PF04954 Siderophore-interacting protein 148 294 3.2E-36 T 28-03-2018 IPR007037 Siderophore-interacting protein SmaCSM2_RS16055 2a74cd26afe02fedaee037d9bb1f94dc 298 Gene3D G3DSA:2.40.30.10 2 130 5.6E-33 T 28-03-2018 SmaCSM2_RS05720 b8c658490e4c05d49fc8d0c558a5b287 148 SUPERFAMILY SSF55729 1 138 1.86E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05720 b8c658490e4c05d49fc8d0c558a5b287 148 Pfam PF13673 Acetyltransferase (GNAT) domain 38 140 6.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS05720 b8c658490e4c05d49fc8d0c558a5b287 148 Gene3D G3DSA:3.40.630.30 82 143 2.6E-15 T 28-03-2018 SmaCSM2_RS05720 b8c658490e4c05d49fc8d0c558a5b287 148 Gene3D G3DSA:3.40.630.30 1 81 4.6E-11 T 28-03-2018 SmaCSM2_RS17980 98416740ed529a83832b6ae376be0eba 210 Pfam PF01323 DSBA-like thioredoxin domain 4 184 9.5E-36 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SmaCSM2_RS17980 98416740ed529a83832b6ae376be0eba 210 SUPERFAMILY SSF52833 3 187 2.91E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS17980 98416740ed529a83832b6ae376be0eba 210 Gene3D G3DSA:3.40.30.10 1 190 1.6E-33 T 28-03-2018 SmaCSM2_RS17980 98416740ed529a83832b6ae376be0eba 210 PIRSF PIRSF006386 1 196 2.2E-42 T 28-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 SmaCSM2_RS05545 8b928d7f70529fd2525f4b3b01dc3942 166 Pfam PF13302 Acetyltransferase (GNAT) domain 11 145 6.2E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS05545 8b928d7f70529fd2525f4b3b01dc3942 166 SUPERFAMILY SSF55729 1 151 7.08E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05545 8b928d7f70529fd2525f4b3b01dc3942 166 Gene3D G3DSA:3.40.630.30 2 166 6.0E-20 T 28-03-2018 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 300 1.0E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 SUPERFAMILY SSF52283 2 138 1.68E-37 T 28-03-2018 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 SUPERFAMILY SSF51735 106 301 8.48E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 Gene3D G3DSA:3.40.50.720 132 300 1.8E-43 T 28-03-2018 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 Gene3D G3DSA:3.40.50.720 1 131 1.2E-35 T 28-03-2018 SmaCSM2_RS05975 7febe8cef73c0754c6d532ecb48f8d73 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 331 1.7E-29 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 Gene3D G3DSA:1.10.10.10 1 84 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 SUPERFAMILY SSF46785 1 83 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 Gene3D G3DSA:3.40.190.10 177 268 1.1E-23 T 28-03-2018 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 Gene3D G3DSA:3.40.190.10 89 176 4.6E-21 T 28-03-2018 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 SUPERFAMILY SSF53850 89 288 2.17E-35 T 28-03-2018 SmaCSM2_RS04910 109d2b9407dd16eeed75dfd1aeaff061 292 Pfam PF03466 LysR substrate binding domain 88 289 6.1E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS19870 b86f97e406cbc8ba74f318ed3b03178d 563 Gene3D G3DSA:1.10.510.10 250 375 0.0022 T 28-03-2018 SmaCSM2_RS19870 b86f97e406cbc8ba74f318ed3b03178d 563 Gene3D G3DSA:3.30.200.20 103 245 9.1E-27 T 28-03-2018 SmaCSM2_RS19870 b86f97e406cbc8ba74f318ed3b03178d 563 SUPERFAMILY SSF56112 194 360 1.11E-24 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS19870 b86f97e406cbc8ba74f318ed3b03178d 563 SUPERFAMILY SSF56112 95 159 1.11E-24 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS19870 b86f97e406cbc8ba74f318ed3b03178d 563 Pfam PF03109 ABC1 family 113 230 8.4E-34 T 28-03-2018 IPR004147 UbiB domain SmaCSM2_RS06540 e631676a8cbdbdc205dcb4d605d3ff23 121 SUPERFAMILY SSF46785 20 119 2.35E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06540 e631676a8cbdbdc205dcb4d605d3ff23 121 Pfam PF03551 Transcriptional regulator PadR-like family 24 99 1.7E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SmaCSM2_RS06540 e631676a8cbdbdc205dcb4d605d3ff23 121 Gene3D G3DSA:1.10.10.10 1 121 7.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19310 5e7c1729619c77a06ab01b30cf4186ee 275 SUPERFAMILY SSF51621 10 263 1.88E-57 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SmaCSM2_RS19310 5e7c1729619c77a06ab01b30cf4186ee 275 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 250 8.8E-64 T 28-03-2018 SmaCSM2_RS19310 5e7c1729619c77a06ab01b30cf4186ee 275 Gene3D G3DSA:3.20.20.60 1 274 9.5E-52 T 28-03-2018 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 88 103 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 88 110 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 178 196 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 206 225 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 425 445 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 362 384 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 PRINTS PR00175 Sodium/alanine symporter signature 297 315 1.7E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 Pfam PF01235 Sodium:alanine symporter family 51 467 1.3E-153 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17075 b44ef99cb2b0e35849c8e0b39044fa6a 483 TIGRFAM TIGR00835 agcS: amino acid carrier protein 15 456 2.4E-144 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 Gene3D G3DSA:1.20.1250.20 1 197 4.4E-33 T 28-03-2018 SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 SUPERFAMILY SSF103473 463 486 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 SUPERFAMILY SSF103473 3 193 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 SUPERFAMILY SSF103473 244 415 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 Gene3D G3DSA:1.20.1250.20 248 489 3.8E-23 T 28-03-2018 SmaCSM2_RS18870 be18e9646efdb5f1e2e5e882c76092a2 490 Pfam PF07690 Major Facilitator Superfamily 14 405 1.5E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS06115 8530f1742428f58018ea70c1d9d21a04 200 Gene3D G3DSA:1.10.10.690 3 69 2.7E-4 T 28-03-2018 SmaCSM2_RS06115 8530f1742428f58018ea70c1d9d21a04 200 Pfam PF06078 Bacterial protein of unknown function (DUF937) 5 138 6.1E-35 T 28-03-2018 IPR009282 Protein of unknown function DUF937 SmaCSM2_RS19415 ca07514050bf6b8e66b37e3528304ee8 129 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 5 123 9.2E-42 T 28-03-2018 IPR009387 Toxin HigB-2 SmaCSM2_RS19415 ca07514050bf6b8e66b37e3528304ee8 129 PIRSF PIRSF018634 4 127 4.5E-38 T 28-03-2018 IPR009387 Toxin HigB-2 SmaCSM2_RS07255 20360555fb2f4f0072e776f0dade9036 181 Gene3D G3DSA:3.30.700.10 20 169 4.1E-10 T 28-03-2018 SmaCSM2_RS07255 20360555fb2f4f0072e776f0dade9036 181 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 20 36 0.0011 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07255 20360555fb2f4f0072e776f0dade9036 181 SUPERFAMILY SSF54523 20 158 9.42E-16 T 28-03-2018 SmaCSM2_RS07255 20360555fb2f4f0072e776f0dade9036 181 Pfam PF12019 Type II transport protein GspH 57 168 2.9E-18 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS16495 205ed70cda4800b5fe40f2cdd9a2c273 133 Pfam PF00072 Response regulator receiver domain 16 127 4.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16495 205ed70cda4800b5fe40f2cdd9a2c273 133 SUPERFAMILY SSF52172 13 132 4.84E-36 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16495 205ed70cda4800b5fe40f2cdd9a2c273 133 SMART SM00448 14 127 1.9E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16495 205ed70cda4800b5fe40f2cdd9a2c273 133 Gene3D G3DSA:3.40.50.2300 6 133 2.3E-35 T 28-03-2018 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 Gene3D G3DSA:1.10.287.70 574 639 1.2E-14 T 28-03-2018 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 9.6E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 646 0.0 T 28-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 Gene3D G3DSA:1.20.210.10 43 560 2.4E-185 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 1.1E-136 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS20425 c59fb6815bb04edfd6384ba25279e259 658 SUPERFAMILY SSF81442 43 558 3.01E-177 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS05320 6ee8dc9a4f90db65d24905567c1cd263 491 Pfam PF01458 Uncharacterized protein family (UPF0051) 229 462 6.9E-67 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SmaCSM2_RS05320 6ee8dc9a4f90db65d24905567c1cd263 491 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 27 482 1.5E-192 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SmaCSM2_RS05320 6ee8dc9a4f90db65d24905567c1cd263 491 SUPERFAMILY SSF101960 47 488 7.19E-138 T 28-03-2018 SmaCSM2_RS03360 04034dc6efe0ab9b81561de68e4bfe0d 157 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 153 2.9E-53 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SmaCSM2_RS03360 04034dc6efe0ab9b81561de68e4bfe0d 157 Gene3D G3DSA:3.90.960.10 1 157 6.2E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SmaCSM2_RS03360 04034dc6efe0ab9b81561de68e4bfe0d 157 SUPERFAMILY SSF55826 2 153 2.35E-39 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SmaCSM2_RS03360 04034dc6efe0ab9b81561de68e4bfe0d 157 PIRSF PIRSF006181 1 157 1.2E-51 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SmaCSM2_RS03360 04034dc6efe0ab9b81561de68e4bfe0d 157 Pfam PF04073 Aminoacyl-tRNA editing domain 32 145 3.3E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SmaCSM2_RS12785 18d85f7ba1a1046af1b11cf043895e25 549 Gene3D G3DSA:3.30.70.100 428 531 0.0015 T 28-03-2018 SmaCSM2_RS12785 18d85f7ba1a1046af1b11cf043895e25 549 Gene3D G3DSA:1.20.1250.20 220 408 6.2E-16 T 28-03-2018 SmaCSM2_RS12785 18d85f7ba1a1046af1b11cf043895e25 549 Gene3D G3DSA:1.20.1250.20 14 214 1.0E-23 T 28-03-2018 SmaCSM2_RS12785 18d85f7ba1a1046af1b11cf043895e25 549 SUPERFAMILY SSF103473 25 407 6.41E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS12785 18d85f7ba1a1046af1b11cf043895e25 549 Pfam PF05977 Transmembrane secretion effector 15 531 1.7E-183 T 28-03-2018 IPR010290 Transmembrane secretion effector SmaCSM2_RS14660 4e8ddfa40663e0fbc3393768e68ff8e4 84 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 25.955 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SmaCSM2_RS14660 4e8ddfa40663e0fbc3393768e68ff8e4 84 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 3.0E-22 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SmaCSM2_RS14660 4e8ddfa40663e0fbc3393768e68ff8e4 84 Pfam PF01809 Haemolytic domain 4 69 2.1E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SmaCSM2_RS14660 4e8ddfa40663e0fbc3393768e68ff8e4 84 SMART SM01234 2 69 1.8E-46 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SmaCSM2_RS14660 4e8ddfa40663e0fbc3393768e68ff8e4 84 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 75 4.5E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SmaCSM2_RS17460 f98d4ece1b701a40a151b59858dc9b40 124 Gene3D G3DSA:2.40.10.220 2 118 2.4E-13 T 28-03-2018 SmaCSM2_RS17460 f98d4ece1b701a40a151b59858dc9b40 124 Pfam PF07238 PilZ domain 9 112 2.0E-9 T 28-03-2018 IPR009875 PilZ domain GO:0035438 SmaCSM2_RS04550 bdd42f952838db5ee0b8729676730e85 228 Pfam PF07811 TadE-like protein 13 55 2.6E-9 T 28-03-2018 IPR012495 TadE-like SmaCSM2_RS10600 df45fcee73e25b3fc21da0d844bb0ba1 155 SUPERFAMILY SSF52172 6 132 5.69E-29 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS10600 df45fcee73e25b3fc21da0d844bb0ba1 155 Pfam PF00072 Response regulator receiver domain 7 129 8.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10600 df45fcee73e25b3fc21da0d844bb0ba1 155 SMART SM00448 5 129 3.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10600 df45fcee73e25b3fc21da0d844bb0ba1 155 Gene3D G3DSA:3.40.50.2300 3 133 3.2E-27 T 28-03-2018 SmaCSM2_RS05455 f0b81138df26fde5fee42a5d5d06228b 300 SUPERFAMILY SSF52540 2 229 4.6E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05455 f0b81138df26fde5fee42a5d5d06228b 300 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS05455 f0b81138df26fde5fee42a5d5d06228b 300 Gene3D G3DSA:3.40.50.300 1 253 3.7E-57 T 28-03-2018 SmaCSM2_RS05455 f0b81138df26fde5fee42a5d5d06228b 300 Pfam PF00005 ABC transporter 18 167 1.8E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS05455 f0b81138df26fde5fee42a5d5d06228b 300 SMART SM00382 26 238 6.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS11755 19c03096e7b22cb0a387ceca25c3c8c9 245 PRINTS PR01837 MgtC/SapB protein signature 44 62 6.8E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS11755 19c03096e7b22cb0a387ceca25c3c8c9 245 PRINTS PR01837 MgtC/SapB protein signature 74 96 6.8E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS11755 19c03096e7b22cb0a387ceca25c3c8c9 245 PRINTS PR01837 MgtC/SapB protein signature 25 44 6.8E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS11755 19c03096e7b22cb0a387ceca25c3c8c9 245 PRINTS PR01837 MgtC/SapB protein signature 101 125 6.8E-39 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS11755 19c03096e7b22cb0a387ceca25c3c8c9 245 Pfam PF02308 MgtC family 22 147 4.2E-34 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 106 195 2.3E-5 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 1.6E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 SUPERFAMILY SSF47616 81 202 3.9E-24 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 Gene3D G3DSA:1.20.1050.10 99 201 1.0E-21 T 28-03-2018 SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 Gene3D G3DSA:3.40.30.10 1 98 3.1E-30 T 28-03-2018 SmaCSM2_RS19140 b7faf9e75af9aacd9a4ff84e10b13e56 206 SUPERFAMILY SSF52833 1 83 3.3E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 Gene3D G3DSA:3.40.50.2300 1 120 1.0E-32 T 28-03-2018 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 SUPERFAMILY SSF46894 124 223 7.09E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 5.2E-104 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 Pfam PF00072 Response regulator receiver domain 4 113 2.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 Gene3D G3DSA:1.10.10.10 121 228 1.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 6.7E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 SMART SM00448 1 112 1.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 SMART SM00862 146 221 4.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS11925 bfaee09deb62bf65657582ea440044a2 232 SUPERFAMILY SSF52172 1 118 7.68E-39 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS13170 6db1489933e3219e56e42169d4e58d61 181 Gene3D G3DSA:3.40.630.30 3 164 9.3E-24 T 28-03-2018 SmaCSM2_RS13170 6db1489933e3219e56e42169d4e58d61 181 SUPERFAMILY SSF55729 6 153 1.14E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS13170 6db1489933e3219e56e42169d4e58d61 181 Pfam PF13302 Acetyltransferase (GNAT) domain 12 147 2.1E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 SUPERFAMILY SSF88946 19 98 1.18E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 165 3.8E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 SUPERFAMILY SSF88659 95 168 1.2E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 Pfam PF04542 Sigma-70 region 2 19 79 1.9E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 Gene3D G3DSA:1.10.1740.10 5 102 2.7E-14 T 28-03-2018 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 Pfam PF08281 Sigma-70, region 4 117 159 4.4E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12205 c1db23106503c011951be2a6f6422c86 176 Gene3D G3DSA:1.10.10.10 103 175 6.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02065 5624b6cac68ae27a9e55e5907aa7e04c 353 SUPERFAMILY SSF52949 3 146 3.03E-41 T 28-03-2018 SmaCSM2_RS02065 5624b6cac68ae27a9e55e5907aa7e04c 353 SMART SM00506 2 136 8.0E-17 T 28-03-2018 IPR002589 Macro domain SmaCSM2_RS02065 5624b6cac68ae27a9e55e5907aa7e04c 353 Gene3D G3DSA:3.40.220.10 1 270 5.0E-32 T 28-03-2018 SmaCSM2_RS02065 5624b6cac68ae27a9e55e5907aa7e04c 353 Pfam PF01661 Macro domain 19 134 7.8E-18 T 28-03-2018 IPR002589 Macro domain SmaCSM2_RS12635 5f897a7603d0660dea9ed028b4ba2987 314 PIRSF PIRSF018266 2 314 9.7E-63 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS12635 5f897a7603d0660dea9ed028b4ba2987 314 Pfam PF16220 Domain of unknown function (DUF4880) 11 51 1.5E-8 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS12635 5f897a7603d0660dea9ed028b4ba2987 314 Pfam PF04773 FecR protein 108 202 4.9E-13 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS10765 b9f01bf472943303bda9cb824ee4fec7 224 SUPERFAMILY SSF47413 13 68 1.24E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS10765 b9f01bf472943303bda9cb824ee4fec7 224 Pfam PF01381 Helix-turn-helix 19 66 9.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS10765 b9f01bf472943303bda9cb824ee4fec7 224 SMART SM00530 18 72 1.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS10765 b9f01bf472943303bda9cb824ee4fec7 224 Gene3D G3DSA:1.10.260.40 10 78 1.2E-13 T 28-03-2018 SmaCSM2_RS15405 bdd0a19665275f6134790b6455bb6f57 223 Pfam PF01738 Dienelactone hydrolase family 15 221 3.0E-35 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SmaCSM2_RS15405 bdd0a19665275f6134790b6455bb6f57 223 Gene3D G3DSA:3.40.50.1820 1 221 1.6E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS15405 bdd0a19665275f6134790b6455bb6f57 223 SUPERFAMILY SSF53474 2 223 2.09E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 Pfam PF13622 Thioesterase-like superfamily 31 286 2.6E-61 T 28-03-2018 SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 SUPERFAMILY SSF54637 120 287 4.71E-56 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 Gene3D G3DSA:3.10.129.10 136 290 2.7E-54 T 28-03-2018 SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 Gene3D G3DSA:3.10.129.10 6 120 1.8E-41 T 28-03-2018 SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 SUPERFAMILY SSF54637 8 117 1.04E-39 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS05860 8fd958088518249fe71a6f546f2d63bf 302 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 16 287 1.5E-93 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 41.455 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Gene3D G3DSA:3.40.50.20 1 150 2.3E-43 T 28-03-2018 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 5.3E-76 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 PIRSF PIRSF039102 1 359 1.1E-126 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 SUPERFAMILY SSF52440 3 139 1.25E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Pfam PF01820 D-ala D-ala ligase N-terminus 5 130 1.9E-29 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Gene3D G3DSA:3.30.470.20 214 359 7.3E-41 T 28-03-2018 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 6.2E-110 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 Gene3D G3DSA:3.30.1490.20 155 213 6.1E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS00900 3cd081057e5b69b3c7cf12697f18d565 371 SUPERFAMILY SSF56059 140 354 4.42E-60 T 28-03-2018 SmaCSM2_RS12625 a1641c001917448c00c7e81a6e1ef58d 126 SUPERFAMILY SSF54593 2 125 2.34E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS12625 a1641c001917448c00c7e81a6e1ef58d 126 Gene3D G3DSA:3.10.180.10 1 126 2.2E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 Hamap MF_00415 Flagellar L-ring protein [flgH]. 4 227 25.951 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 PRINTS PR01008 Flagellar L-ring protein signature 70 82 2.5E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 PRINTS PR01008 Flagellar L-ring protein signature 143 158 2.5E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 PRINTS PR01008 Flagellar L-ring protein signature 169 185 2.5E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 PRINTS PR01008 Flagellar L-ring protein signature 190 204 2.5E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 PRINTS PR01008 Flagellar L-ring protein signature 206 220 2.5E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS10270 79fbbb04a6c4c9bbf6631501107fd745 230 Pfam PF02107 Flagellar L-ring protein 48 227 2.6E-58 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 PIRSF PIRSF006755 8 227 2.0E-73 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 SUPERFAMILY SSF52540 10 216 1.33E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 Pfam PF13500 AAA domain 10 216 4.0E-40 T 28-03-2018 SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 8 217 28.033 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 12 182 2.9E-47 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SmaCSM2_RS02535 df19111bbad51bb367a6dcefc121e6b5 227 Gene3D G3DSA:3.40.50.300 8 224 1.0E-60 T 28-03-2018 SmaCSM2_RS06965 0fd11c5f5f3ab91143d9c1c5d2548140 104 Pfam PF12365 Protein of unknown function (DUF3649) 73 98 2.2E-9 T 28-03-2018 IPR022109 Protein of unknown function DUF3649 SmaCSM2_RS21375 847638ac4084434926446da829d83a2a 554 Gene3D G3DSA:1.20.1250.20 230 554 1.6E-30 T 28-03-2018 SmaCSM2_RS21375 847638ac4084434926446da829d83a2a 554 SUPERFAMILY SSF103473 457 550 1.66E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS21375 847638ac4084434926446da829d83a2a 554 SUPERFAMILY SSF103473 19 339 1.66E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS21375 847638ac4084434926446da829d83a2a 554 Gene3D G3DSA:1.20.1250.20 11 229 5.9E-25 T 28-03-2018 SmaCSM2_RS21375 847638ac4084434926446da829d83a2a 554 Pfam PF00083 Sugar (and other) transporter 24 238 8.2E-29 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 Gene3D G3DSA:3.40.250.10 167 300 4.5E-21 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 SMART SM00450 175 294 1.3E-9 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 SMART SM00450 11 151 1.5E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 SUPERFAMILY SSF52821 177 299 6.68E-29 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 Gene3D G3DSA:3.40.250.10 7 164 1.7E-30 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 SUPERFAMILY SSF52821 6 159 4.85E-38 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 Pfam PF00581 Rhodanese-like domain 35 148 6.4E-18 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS06935 50bedb879b7f3654b30636b51e2a4eac 300 Pfam PF00581 Rhodanese-like domain 178 290 1.5E-7 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS18230 e81fb14edaafde0da020d3035125907f 429 Gene3D G3DSA:1.20.1250.20 10 231 3.4E-18 T 28-03-2018 SmaCSM2_RS18230 e81fb14edaafde0da020d3035125907f 429 SUPERFAMILY SSF103473 10 419 3.66E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18230 e81fb14edaafde0da020d3035125907f 429 Pfam PF07690 Major Facilitator Superfamily 22 381 8.8E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS18230 e81fb14edaafde0da020d3035125907f 429 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 97 415 5.2E-127 T 28-03-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 SmaCSM2_RS18230 e81fb14edaafde0da020d3035125907f 429 Gene3D G3DSA:1.20.1250.20 236 421 3.5E-13 T 28-03-2018 SmaCSM2_RS03640 a2b3bc1c57b590bea1b560b905e00dc5 318 SUPERFAMILY SSF51569 5 316 4.81E-93 T 28-03-2018 SmaCSM2_RS03640 a2b3bc1c57b590bea1b560b905e00dc5 318 ProSitePatterns PS00958 Transaldolase active site. 131 148 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SmaCSM2_RS03640 a2b3bc1c57b590bea1b560b905e00dc5 318 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 16 313 1.1E-85 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SmaCSM2_RS03640 a2b3bc1c57b590bea1b560b905e00dc5 318 Gene3D G3DSA:3.20.20.70 4 318 1.2E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS03640 a2b3bc1c57b590bea1b560b905e00dc5 318 ProSitePatterns PS01054 Transaldolase signature 1. 33 41 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SmaCSM2_RS12030 de236234c47342fbfef7ab9e72edea6b 484 Gene3D G3DSA:2.40.160.20 159 430 2.9E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS12030 de236234c47342fbfef7ab9e72edea6b 484 SUPERFAMILY SSF48452 79 162 2.53E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12030 de236234c47342fbfef7ab9e72edea6b 484 Gene3D G3DSA:1.25.40.10 27 158 3.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12030 de236234c47342fbfef7ab9e72edea6b 484 Pfam PF04575 Protein of unknown function (DUF560) 193 484 4.5E-55 T 28-03-2018 IPR007655 Protein of unknown function DUF560 SmaCSM2_RS18505 7f3bc78cc3d01ea221208bea78c79446 398 SUPERFAMILY SSF53383 14 395 2.53E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS18505 7f3bc78cc3d01ea221208bea78c79446 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 239 252 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SmaCSM2_RS18505 7f3bc78cc3d01ea221208bea78c79446 398 Gene3D G3DSA:3.90.1150.10 300 397 1.0E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS18505 7f3bc78cc3d01ea221208bea78c79446 398 Gene3D G3DSA:3.40.640.10 55 299 3.1E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS18505 7f3bc78cc3d01ea221208bea78c79446 398 Pfam PF00155 Aminotransferase class I and II 41 389 5.6E-52 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS00950 5b1a9da4419b87a4c8342890a3048c51 143 Gene3D G3DSA:3.30.160.20 5 143 2.0E-39 T 28-03-2018 SmaCSM2_RS00950 5b1a9da4419b87a4c8342890a3048c51 143 Pfam PF00472 RF-1 domain 11 137 7.9E-22 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SmaCSM2_RS00950 5b1a9da4419b87a4c8342890a3048c51 143 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 25 41 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SmaCSM2_RS00950 5b1a9da4419b87a4c8342890a3048c51 143 SUPERFAMILY SSF110916 9 99 4.71E-12 T 28-03-2018 SmaCSM2_RS14865 5761c4b9062bf0df64020478ea45c0b3 221 SMART SM00507 114 167 2.9E-10 T 28-03-2018 IPR003615 HNH nuclease SmaCSM2_RS14865 5761c4b9062bf0df64020478ea45c0b3 221 Pfam PF14279 HNH endonuclease 127 181 4.3E-15 T 28-03-2018 IPR029471 HNH endonuclease 5 SmaCSM2_RS14865 5761c4b9062bf0df64020478ea45c0b3 221 Gene3D G3DSA:3.40.1800.10 110 181 1.3E-18 T 28-03-2018 SmaCSM2_RS09805 30847bace4e5b3cb4118e1c3001dee8e 193 Gene3D G3DSA:3.40.50.360 4 192 3.5E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS09805 30847bace4e5b3cb4118e1c3001dee8e 193 Pfam PF02525 Flavodoxin-like fold 4 176 5.7E-37 T 28-03-2018 IPR003680 Flavodoxin-like fold SmaCSM2_RS09805 30847bace4e5b3cb4118e1c3001dee8e 193 SUPERFAMILY SSF52218 5 192 1.05E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS17275 761d5ddfe628acb8eaee1ca05acebb3d 177 PIRSF PIRSF016481 2 177 1.2E-57 T 28-03-2018 IPR007446 Pilus assembly protein PilP SmaCSM2_RS17275 761d5ddfe628acb8eaee1ca05acebb3d 177 Pfam PF04351 Pilus assembly protein, PilP 33 174 5.1E-46 T 28-03-2018 IPR007446 Pilus assembly protein PilP SmaCSM2_RS07130 f7bc338d5d75a322b2d495f37a091629 307 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 199 227 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 SmaCSM2_RS07130 f7bc338d5d75a322b2d495f37a091629 307 Pfam PF01464 Transglycosylase SLT domain 183 278 1.3E-25 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS07130 f7bc338d5d75a322b2d495f37a091629 307 Gene3D G3DSA:1.10.530.10 162 304 1.3E-44 T 28-03-2018 SmaCSM2_RS07130 f7bc338d5d75a322b2d495f37a091629 307 SUPERFAMILY SSF53955 175 301 3.64E-44 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS12880 fe60181cf139d8f989bf81aeacd78a0e 259 PIRSF PIRSF001273 4 252 4.0E-65 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 SmaCSM2_RS12880 fe60181cf139d8f989bf81aeacd78a0e 259 SUPERFAMILY SSF54197 28 247 1.12E-63 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SmaCSM2_RS12880 fe60181cf139d8f989bf81aeacd78a0e 259 Gene3D G3DSA:3.30.428.30 26 247 1.1E-64 T 28-03-2018 SmaCSM2_RS12880 fe60181cf139d8f989bf81aeacd78a0e 259 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 28 247 1.6E-72 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 SUPERFAMILY SSF48498 94 172 1.29E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 Gene3D G3DSA:1.10.10.60 54 160 1.9E-11 T 28-03-2018 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 SUPERFAMILY SSF46689 7 85 6.8E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 Gene3D G3DSA:1.10.10.60 1 53 1.1E-18 T 28-03-2018 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS14945 7d9c03bc743481324ebd16b308f5a8bf 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 Gene3D G3DSA:3.90.226.10 15 290 3.7E-65 T 28-03-2018 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 284 37.989 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 132 146 1.8E-41 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 203 220 1.8E-41 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 232 243 1.8E-41 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 166 184 1.8E-41 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 254 263 1.8E-41 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 SUPERFAMILY SSF52096 28 286 1.36E-84 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 Pfam PF01039 Carboxyl transferase domain 102 243 7.3E-17 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SmaCSM2_RS15230 78b22613a4dfdc20ac0f5b73898b102d 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 286 2.4E-126 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 Pfam PF08411 Exonuclease C-terminal 206 473 1.7E-92 T 28-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 Gene3D G3DSA:3.30.420.10 1 195 1.1E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 Pfam PF00929 Exonuclease 7 185 7.9E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 SUPERFAMILY SSF53098 4 475 8.76E-118 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 SMART SM00479 4 197 1.0E-4 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS13955 e492b0d0c492ac1fe45246275eec0185 479 PIRSF PIRSF000977 1 479 6.6E-184 T 28-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Pfam PF02779 Transketolase, pyrimidine binding domain 357 528 1.4E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 336 2.3E-152 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Gene3D G3DSA:3.40.50.970 365 541 3.1E-39 T 28-03-2018 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Pfam PF02780 Transketolase, C-terminal domain 547 658 5.5E-17 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 SUPERFAMILY SSF52922 536 665 8.11E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Gene3D G3DSA:3.40.50.920 542 665 7.0E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 TIGRFAM TIGR00232 tktlase_bact: transketolase 8 665 1.8E-285 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 SMART SM00861 357 528 1.3E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 ProSitePatterns PS00802 Transketolase signature 2. 470 486 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 SUPERFAMILY SSF52518 344 528 4.98E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 SUPERFAMILY SSF52518 6 329 3.48E-117 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS17230 832b6cddc16f57a1d61e2d691d8c3ab9 665 Gene3D G3DSA:3.40.50.970 1 364 1.8E-118 T 28-03-2018 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 Gene3D G3DSA:3.30.450.90 1 99 1.8E-17 T 28-03-2018 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 Pfam PF00437 Type II/IV secretion system protein 9 270 1.4E-36 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 341 1.1E-132 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 Gene3D G3DSA:3.40.50.300 110 272 2.2E-25 T 28-03-2018 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 Gene3D G3DSA:3.40.50.300 273 346 1.4E-11 T 28-03-2018 SmaCSM2_RS02640 4b56665206eb93a29744ca8b2b644a02 375 SUPERFAMILY SSF52540 7 337 7.7E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS06930 40e22b86de3f4b1d44d3aa506498ee3d 267 Pfam PF06945 Protein of unknown function (DUF1289) 10 53 2.6E-17 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 SmaCSM2_RS06930 40e22b86de3f4b1d44d3aa506498ee3d 267 Pfam PF00293 NUDIX domain 110 218 7.1E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS06930 40e22b86de3f4b1d44d3aa506498ee3d 267 Gene3D G3DSA:3.90.79.10 90 263 5.8E-37 T 28-03-2018 SmaCSM2_RS06930 40e22b86de3f4b1d44d3aa506498ee3d 267 SUPERFAMILY SSF55811 103 256 4.2E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS16185 3bfcd764646d7915741fc77d73f66039 108 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 94 1.1E-10 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 SUPERFAMILY SSF56935 382 442 1.21E-85 T 28-03-2018 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 SUPERFAMILY SSF56935 37 235 1.21E-85 T 28-03-2018 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 SUPERFAMILY SSF56935 481 696 1.21E-85 T 28-03-2018 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 SUPERFAMILY SSF56935 727 929 1.21E-85 T 28-03-2018 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 SUPERFAMILY SSF56935 305 353 1.21E-85 T 28-03-2018 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 168 2.6E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 Gene3D G3DSA:2.40.170.20 185 929 1.9E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 Pfam PF00593 TonB dependent receptor 385 927 2.7E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15425 d344fe4f95c37153b46f48a522d3d33a 929 Gene3D G3DSA:2.170.130.10 27 175 9.3E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS08975 142e187e9d6960961b212d35429eda40 109 Gene3D G3DSA:3.30.1450.10 33 100 1.2E-5 T 28-03-2018 SmaCSM2_RS12920 47a72c55a41e7ca93ef4f0a90fac8d75 150 PRINTS PR01837 MgtC/SapB protein signature 16 35 1.7E-31 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12920 47a72c55a41e7ca93ef4f0a90fac8d75 150 PRINTS PR01837 MgtC/SapB protein signature 101 125 1.7E-31 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12920 47a72c55a41e7ca93ef4f0a90fac8d75 150 PRINTS PR01837 MgtC/SapB protein signature 35 53 1.7E-31 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12920 47a72c55a41e7ca93ef4f0a90fac8d75 150 PRINTS PR01837 MgtC/SapB protein signature 72 94 1.7E-31 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS12920 47a72c55a41e7ca93ef4f0a90fac8d75 150 Pfam PF02308 MgtC family 14 147 2.3E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SmaCSM2_RS18845 40956bfe4e697b5efc3954a6e320b305 297 Gene3D G3DSA:3.40.50.720 1 289 2.0E-42 T 28-03-2018 SmaCSM2_RS18845 40956bfe4e697b5efc3954a6e320b305 297 SUPERFAMILY SSF51735 1 277 7.0E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18845 40956bfe4e697b5efc3954a6e320b305 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 160 7.7E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 SUPERFAMILY SSF55594 3 88 1.83E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 Gene3D G3DSA:3.30.1340.10 1 87 9.1E-29 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.2E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.2E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.2E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 5.2E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 5.3E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SmaCSM2_RS05070 54933e1eb359be8066c00edf62ed802f 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 7.3E-35 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 Gene3D G3DSA:4.10.520.10 1 90 1.7E-36 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 SMART SM00411 1 90 1.1E-44 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.4E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.4E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.4E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS04435 3346e56c125015143114d6b454d1aa76 90 SUPERFAMILY SSF47729 1 90 1.62E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 Pfam PF01266 FAD dependent oxidoreductase 3 397 6.0E-70 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 SUPERFAMILY SSF54373 269 359 3.66E-17 T 28-03-2018 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 48.238 T 28-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 SUPERFAMILY SSF51905 1 54 2.72E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 SUPERFAMILY SSF51905 359 416 2.72E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 SUPERFAMILY SSF51905 107 269 2.72E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS02425 e68848b8c2b6ba143a652efc1e167cfc 434 Gene3D G3DSA:3.50.50.60 1 429 8.3E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18915 7096e29a9eec8b57ecc3b905be9b0664 297 SUPERFAMILY SSF103481 35 138 5.49E-13 T 28-03-2018 SmaCSM2_RS18915 7096e29a9eec8b57ecc3b905be9b0664 297 Pfam PF00892 EamA-like transporter family 150 280 1.1E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS18915 7096e29a9eec8b57ecc3b905be9b0664 297 Pfam PF00892 EamA-like transporter family 3 135 2.3E-25 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS18915 7096e29a9eec8b57ecc3b905be9b0664 297 SUPERFAMILY SSF103481 188 283 1.15E-9 T 28-03-2018 SmaCSM2_RS07980 75a7582baff3d35f7e20655e26131df8 208 Gene3D G3DSA:3.40.190.80 49 202 9.1E-5 T 28-03-2018 SmaCSM2_RS07980 75a7582baff3d35f7e20655e26131df8 208 Pfam PF01865 Protein of unknown function DUF47 61 197 3.8E-6 T 28-03-2018 IPR018445 Putative phosphate transport regulator SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 Gene3D G3DSA:3.90.79.10 207 350 4.8E-29 T 28-03-2018 SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 SUPERFAMILY SSF52374 9 180 6.76E-20 T 28-03-2018 SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 Pfam PF00293 NUDIX domain 219 332 2.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 Pfam PF01467 Cytidylyltransferase-like 9 71 1.5E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 65 1.2E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 Gene3D G3DSA:3.40.50.620 3 206 2.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01160 8e90bd12aa5e92763141b736073c54dc 351 SUPERFAMILY SSF55811 204 349 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 SUPERFAMILY SSF53474 392 646 2.1E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 Gene3D G3DSA:2.140.10.30 15 369 1.5E-11 T 28-03-2018 SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 SUPERFAMILY SSF82171 32 292 1.12E-9 T 28-03-2018 SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 SUPERFAMILY SSF82171 337 383 1.12E-9 T 28-03-2018 SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 Gene3D G3DSA:3.40.50.1820 370 654 1.5E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05735 58267983373fb2f4c29490a995661ab1 662 Pfam PF00326 Prolyl oligopeptidase family 439 646 2.9E-44 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS09350 24b50c4b6e07d4939f241d79b05ab7de 295 Pfam PF00892 EamA-like transporter family 143 270 2.6E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS09350 24b50c4b6e07d4939f241d79b05ab7de 295 Pfam PF00892 EamA-like transporter family 2 133 2.3E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS09350 24b50c4b6e07d4939f241d79b05ab7de 295 SUPERFAMILY SSF103481 177 274 4.97E-16 T 28-03-2018 SmaCSM2_RS09350 24b50c4b6e07d4939f241d79b05ab7de 295 SUPERFAMILY SSF103481 36 137 1.7E-16 T 28-03-2018 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 SUPERFAMILY SSF53686 13 398 2.88E-143 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 401 51.217 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 Gene3D G3DSA:3.40.50.1100 209 401 2.6E-39 T 28-03-2018 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 Gene3D G3DSA:3.40.50.1100 19 208 1.1E-42 T 28-03-2018 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 399 2.9E-186 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 PIRSF PIRSF001413 5 403 9.0E-158 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SmaCSM2_RS15245 2c4a5a54553714991d8a2164f6fe0bcf 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 63 388 7.3E-46 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS07560 750d241e1eb6b229f554a6181f8f0d7a 164 Pfam PF04002 RadC-like JAB domain 44 162 2.0E-39 T 28-03-2018 IPR025657 RadC-like JAB domain SmaCSM2_RS07560 750d241e1eb6b229f554a6181f8f0d7a 164 TIGRFAM TIGR00608 radc: DNA repair protein RadC 27 164 9.6E-40 T 28-03-2018 IPR001405 RadC protein SmaCSM2_RS07560 750d241e1eb6b229f554a6181f8f0d7a 164 SUPERFAMILY SSF102712 59 141 3.79E-5 T 28-03-2018 SmaCSM2_RS07560 750d241e1eb6b229f554a6181f8f0d7a 164 Gene3D G3DSA:3.40.140.10 41 164 7.0E-42 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Pfam PF01568 Molydopterin dinucleotide binding domain 1088 1202 2.7E-20 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Gene3D G3DSA:3.30.2070.10 794 834 5.3E-5 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 SUPERFAMILY SSF50692 1080 1236 4.75E-47 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Pfam PF00384 Molybdopterin oxidoreductase 108 830 5.1E-165 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Gene3D G3DSA:2.40.40.20 1048 1238 6.3E-44 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Gene3D G3DSA:3.40.228.10 224 659 5.5E-98 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 4 40 8.1E-15 T 28-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Gene3D G3DSA:4.10.1200.10 1 24 5.4E-11 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1235 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 SMART SM00926 43 105 6.6E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 SUPERFAMILY SSF53706 7 1069 0.0 T 28-03-2018 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1125 1152 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 SmaCSM2_RS12295 fd04a31de2490bb9833bc270540c922d 1251 Gene3D G3DSA:2.20.25.90 55 98 1.3E-28 T 28-03-2018 SmaCSM2_RS03445 3563518832ed7f209f95671f9deeef8d 199 SUPERFAMILY SSF144064 16 190 3.01E-27 T 28-03-2018 SmaCSM2_RS03445 3563518832ed7f209f95671f9deeef8d 199 Gene3D G3DSA:3.40.1570.10 4 109 1.8E-9 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Pfam PF13247 4Fe-4S dicluster domain 92 188 3.5E-24 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 290 2.3E-142 T 28-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Gene3D G3DSA:3.30.70.20 157 194 9.2E-5 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 SUPERFAMILY SSF54862 28 290 2.62E-69 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Gene3D G3DSA:3.30.70.20 14 41 0.0029 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Gene3D G3DSA:3.30.70.20 113 156 1.5E-16 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 1.8E-21 T 28-03-2018 IPR015246 Formate dehydrogenase, transmembrane SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 PIRSF PIRSF036298 1 304 2.0E-154 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Gene3D G3DSA:1.20.5.480 249 291 2.5E-20 T 28-03-2018 SmaCSM2_RS17395 dc42c51c2be6ec676fe10011c175dbea 305 Gene3D G3DSA:3.30.70.20 42 112 4.3E-19 T 28-03-2018 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 8.2E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 8.2E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 8.2E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 SUPERFAMILY SSF47729 3 92 2.65E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 Gene3D G3DSA:4.10.520.10 1 98 3.5E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 96 1.4E-47 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 29.696 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 SMART SM00411 3 92 1.3E-42 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 Pfam PF00216 Bacterial DNA-binding protein 3 91 4.7E-32 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SmaCSM2_RS15005 0fcee5ea382b9f65957ff6fdabfae813 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SmaCSM2_RS02645 c84e10615628937a71850a94a74714eb 121 Pfam PF14346 Domain of unknown function (DUF4398) 13 111 7.5E-14 T 28-03-2018 IPR025511 Domain of unknown function DUF4398 SmaCSM2_RS06505 8e71310f15303485aeda4b10f6a71564 602 Pfam PF05960 Bacterial protein of unknown function (DUF885) 60 596 1.1E-110 T 28-03-2018 IPR010281 Protein of unknown function DUF885 SmaCSM2_RS10365 d9b9c72c3703802df81e4efe38164870 204 Gene3D G3DSA:1.10.3890.10 4 204 3.9E-64 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 SmaCSM2_RS10365 d9b9c72c3703802df81e4efe38164870 204 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 204 31.414 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 SmaCSM2_RS10365 d9b9c72c3703802df81e4efe38164870 204 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 22 195 6.0E-68 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 SmaCSM2_RS10365 d9b9c72c3703802df81e4efe38164870 204 SUPERFAMILY SSF101322 4 202 1.23E-61 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 SmaCSM2_RS10365 d9b9c72c3703802df81e4efe38164870 204 Pfam PF04356 Protein of unknown function (DUF489) 7 196 7.7E-63 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 348 360 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 316 322 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 78 90 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 4.8E-27 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 Pfam PF01266 FAD dependent oxidoreductase 5 329 8.9E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 SUPERFAMILY SSF51905 2 299 7.34E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 Gene3D G3DSA:3.40.50.20 2 85 0.0075 T 28-03-2018 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 Gene3D G3DSA:3.30.9.10 190 323 2.8E-35 T 28-03-2018 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 Gene3D G3DSA:3.30.9.10 86 189 5.9E-18 T 28-03-2018 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 9 26 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS18755 7d872246d19aa1c3aa0cbf0c253ecd4f 501 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 353 363 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 SUPERFAMILY SSF46785 10 145 4.44E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 Pfam PF01047 MarR family 44 94 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 Gene3D G3DSA:1.10.10.10 3 146 2.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 1.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS06750 833ad836e9b4ecba8eee72a3b5b74d74 147 SMART SM00347 30 130 6.6E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SmaCSM2_RS06325 e153b8f187657500d16b5a50968591f8 181 Gene3D G3DSA:3.40.630.30 13 181 3.0E-20 T 28-03-2018 SmaCSM2_RS06325 e153b8f187657500d16b5a50968591f8 181 Pfam PF13302 Acetyltransferase (GNAT) domain 22 161 5.9E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS06325 e153b8f187657500d16b5a50968591f8 181 SUPERFAMILY SSF55729 24 169 2.52E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS19955 d486b6fab3e10d5deafc127c7bb63e66 83 Pfam PF04380 Membrane fusogenic activity 1 77 5.1E-25 T 28-03-2018 IPR007475 Membrane fusogenic activity SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.7E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 1.7E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.7E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PIRSF PIRSF006431 1 315 6.8E-126 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 Pfam PF00561 alpha/beta hydrolase fold 36 296 4.8E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 311 1.4E-120 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 SUPERFAMILY SSF53474 2 298 1.89E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11735 64f40b8891a65f1f363f4a8049859527 315 Gene3D G3DSA:3.40.50.1820 1 314 2.6E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 PRINTS PR00147 DNA photolyase signature 340 358 1.2E-20 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 PRINTS PR00147 DNA photolyase signature 379 393 1.2E-20 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 PRINTS PR00147 DNA photolyase signature 320 336 1.2E-20 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 PRINTS PR00147 DNA photolyase signature 140 156 1.2E-20 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 SUPERFAMILY SSF52425 3 204 3.14E-57 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 Gene3D G3DSA:1.25.40.80 129 287 5.7E-41 T 28-03-2018 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 Gene3D G3DSA:3.40.50.620 1 128 5.0E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 SUPERFAMILY SSF48173 189 467 9.81E-96 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 Pfam PF03441 FAD binding domain of DNA photolyase 270 466 3.5E-75 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 Pfam PF00875 DNA photolyase 4 162 8.2E-52 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SmaCSM2_RS08580 88c93dd098e6fa74344d311cd749f985 471 Gene3D G3DSA:1.10.579.10 288 470 9.7E-67 T 28-03-2018 SmaCSM2_RS20320 70c3bbc98e4c1d7135907b09f131f34f 94 Gene3D G3DSA:3.30.1190.10 38 73 4.4E-5 T 28-03-2018 SmaCSM2_RS20320 70c3bbc98e4c1d7135907b09f131f34f 94 Pfam PF01381 Helix-turn-helix 17 65 2.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS20320 70c3bbc98e4c1d7135907b09f131f34f 94 Gene3D G3DSA:1.10.10.60 8 37 5.5E-8 T 28-03-2018 SmaCSM2_RS20320 70c3bbc98e4c1d7135907b09f131f34f 94 SUPERFAMILY SSF47413 5 66 5.09E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS20320 70c3bbc98e4c1d7135907b09f131f34f 94 SMART SM00530 16 70 6.2E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 Gene3D G3DSA:2.40.10.10 46 58 4.1E-4 T 28-03-2018 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 Pfam PF00089 Trypsin 49 158 1.8E-5 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 SMART SM00020 19 261 4.4E-6 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 1.4E-9 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 204 216 1.4E-9 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 48 63 1.4E-9 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 SUPERFAMILY SSF50494 47 266 2.02E-29 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 Gene3D G3DSA:2.40.10.10 126 269 9.4E-15 T 28-03-2018 SmaCSM2_RS11405 3b205a8d4ea24a67172fce9ce53a4bc5 271 Gene3D G3DSA:2.40.10.10 59 125 5.0E-9 T 28-03-2018 SmaCSM2_RS20415 b690676cb1ffb88e9ca47a0f33bc7cee 110 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 13 108 3.2E-35 T 28-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 SmaCSM2_RS20415 b690676cb1ffb88e9ca47a0f33bc7cee 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 93 4.9E-16 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 SmaCSM2_RS16465 42898fa23d5591b11c3d20d3cf043386 154 SUPERFAMILY SSF50341 6 145 7.06E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16465 42898fa23d5591b11c3d20d3cf043386 154 Pfam PF01584 CheW-like domain 11 145 8.7E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16465 42898fa23d5591b11c3d20d3cf043386 154 Gene3D G3DSA:2.40.50.180 29 133 7.6E-7 T 28-03-2018 SmaCSM2_RS16465 42898fa23d5591b11c3d20d3cf043386 154 SMART SM00260 6 146 0.0077 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS04645 555b41a8db06d548dfe1b90777fbc372 465 Pfam PF00589 Phage integrase family 251 410 4.3E-10 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS04645 555b41a8db06d548dfe1b90777fbc372 465 SUPERFAMILY SSF56349 170 412 3.53E-37 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS04645 555b41a8db06d548dfe1b90777fbc372 465 SUPERFAMILY SSF56349 88 140 3.53E-37 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS04645 555b41a8db06d548dfe1b90777fbc372 465 Gene3D G3DSA:1.10.443.10 224 424 4.9E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS04645 555b41a8db06d548dfe1b90777fbc372 465 Gene3D G3DSA:1.10.150.130 82 223 6.9E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 SUPERFAMILY SSF55194 3 182 1.57E-60 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 184 23.415 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 Gene3D G3DSA:1.10.132.20 90 184 5.6E-35 T 28-03-2018 SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 Pfam PF01765 Ribosome recycling factor 20 182 6.2E-56 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 184 2.6E-60 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SmaCSM2_RS06630 a43c25ef1bc1a0f262c98b7877f1f265 184 Gene3D G3DSA:3.30.1360.40 31 89 5.1E-18 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SmaCSM2_RS19080 5f95b42de219b2120254a72bfff7fac4 309 Pfam PF06271 RDD family 119 254 2.6E-27 T 28-03-2018 IPR010432 RDD SmaCSM2_RS19080 5f95b42de219b2120254a72bfff7fac4 309 Pfam PF14237 Domain of unknown function (DUF4339) 4 47 1.7E-17 T 28-03-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 SmaCSM2_RS19080 5f95b42de219b2120254a72bfff7fac4 309 Gene3D G3DSA:3.30.1490.40 2 63 1.4E-4 T 28-03-2018 IPR035445 GYF-like domain SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 157 276 5.5E-30 T 28-03-2018 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 Gene3D G3DSA:2.60.120.10 19 154 5.3E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 SMART SM00100 17 142 8.7E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 Gene3D G3DSA:3.40.50.450 156 296 6.3E-4 T 28-03-2018 SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 Pfam PF00027 Cyclic nucleotide-binding domain 45 125 1.5E-10 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS04700 56b4522be189c148a8bee72eee6d9ecd 306 SUPERFAMILY SSF51206 35 148 1.22E-18 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 SUPERFAMILY SSF47781 318 379 8.0E-8 T 28-03-2018 IPR010994 RuvA domain 2-like SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 Gene3D G3DSA:3.20.20.70 42 317 1.9E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 Gene3D G3DSA:1.10.150.320 325 391 0.0017 T 28-03-2018 SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 SUPERFAMILY SSF102114 45 191 2.09E-15 T 28-03-2018 SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 SMART SM00729 56 295 0.0053 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS02635 3df5e3bc69836b72f6e75e8ca52dba2e 427 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 5 413 1.0E-169 T 28-03-2018 IPR023874 DNA modification/repair radical SAM protein, putative SmaCSM2_RS18535 e9338ad06544b560ea352b5d73a7050b 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 225 7.2E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS18535 e9338ad06544b560ea352b5d73a7050b 229 SUPERFAMILY SSF161098 20 219 1.57E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS18535 e9338ad06544b560ea352b5d73a7050b 229 Gene3D G3DSA:1.10.3720.10 14 229 2.7E-35 T 28-03-2018 SmaCSM2_RS07375 feae2d8f854d7eb42ba43d670b897fe3 242 Gene3D G3DSA:3.40.50.300 7 241 9.1E-66 T 28-03-2018 SmaCSM2_RS07375 feae2d8f854d7eb42ba43d670b897fe3 242 SUPERFAMILY SSF52540 11 237 2.42E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07375 feae2d8f854d7eb42ba43d670b897fe3 242 SMART SM00382 39 227 3.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS07375 feae2d8f854d7eb42ba43d670b897fe3 242 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS07375 feae2d8f854d7eb42ba43d670b897fe3 242 Pfam PF00005 ABC transporter 30 179 2.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS02045 f641288ba1ec590c5ca4ab39a47ede0e 265 Pfam PF04954 Siderophore-interacting protein 140 257 2.0E-35 T 28-03-2018 IPR007037 Siderophore-interacting protein SmaCSM2_RS02045 f641288ba1ec590c5ca4ab39a47ede0e 265 Gene3D G3DSA:2.40.30.10 8 132 2.0E-34 T 28-03-2018 SmaCSM2_RS02045 f641288ba1ec590c5ca4ab39a47ede0e 265 Gene3D G3DSA:3.40.50.80 133 265 2.0E-37 T 28-03-2018 SmaCSM2_RS02045 f641288ba1ec590c5ca4ab39a47ede0e 265 SUPERFAMILY SSF63380 8 135 1.61E-14 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS02045 f641288ba1ec590c5ca4ab39a47ede0e 265 Pfam PF08021 Siderophore-interacting FAD-binding domain 20 132 7.0E-37 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SmaCSM2_RS21020 20e70b108c7ae6acfbb72149fe0348bd 126 Gene3D G3DSA:3.30.110.70 20 122 9.5E-30 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 SmaCSM2_RS21020 20e70b108c7ae6acfbb72149fe0348bd 126 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 20 122 22.774 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 SmaCSM2_RS21020 20e70b108c7ae6acfbb72149fe0348bd 126 Pfam PF01906 Putative heavy-metal-binding 21 122 3.8E-33 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 SmaCSM2_RS21020 20e70b108c7ae6acfbb72149fe0348bd 126 SUPERFAMILY SSF117782 21 124 1.7E-34 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 SmaCSM2_RS09380 e9e134f720b4738f480d501e5192a54a 510 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09380 e9e134f720b4738f480d501e5192a54a 510 SUPERFAMILY SSF53720 19 498 8.9E-134 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09380 e9e134f720b4738f480d501e5192a54a 510 Gene3D G3DSA:3.40.309.10 282 478 6.6E-55 T 28-03-2018 SmaCSM2_RS09380 e9e134f720b4738f480d501e5192a54a 510 Gene3D G3DSA:3.40.605.10 15 281 1.8E-74 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09380 e9e134f720b4738f480d501e5192a54a 510 Pfam PF00171 Aldehyde dehydrogenase family 25 491 7.5E-130 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS16130 ffaf5474c5344ec06f6b43960c6e32e9 287 SMART SM00244 19 184 4.7E-14 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS16130 ffaf5474c5344ec06f6b43960c6e32e9 287 Pfam PF01145 SPFH domain / Band 7 family 23 201 2.8E-23 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS16130 ffaf5474c5344ec06f6b43960c6e32e9 287 SUPERFAMILY SSF117892 51 190 2.62E-19 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS16130 ffaf5474c5344ec06f6b43960c6e32e9 287 PIRSF PIRSF005651 1 287 1.1E-77 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 SmaCSM2_RS17630 cbba865187f8becccf2ca02704075f1d 675 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 13 675 3.4E-267 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SmaCSM2_RS17630 cbba865187f8becccf2ca02704075f1d 675 PIRSF PIRSF001265 2 675 6.5E-264 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SmaCSM2_RS17630 cbba865187f8becccf2ca02704075f1d 675 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 4 675 25.551 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SmaCSM2_RS17630 cbba865187f8becccf2ca02704075f1d 675 Pfam PF03030 Inorganic H+ pyrophosphatase 15 670 2.6E-270 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 Pfam PF12147 Putative methyltransferase 273 581 2.6E-155 T 28-03-2018 IPR022744 Methyltransferase domain, putative SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 Pfam PF12146 Serine aminopeptidase, S33 30 265 8.7E-67 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 SUPERFAMILY SSF53335 371 567 1.28E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 Gene3D G3DSA:3.40.50.150 353 570 2.0E-18 T 28-03-2018 SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 SUPERFAMILY SSF53474 4 281 6.02E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS19385 e58a537a6aac1c63f3f0676ebe13c240 583 Gene3D G3DSA:3.40.50.1820 2 289 6.8E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS17660 cbb5fd1dbe6ee19c8cded40b158f4209 85 Pfam PF10982 Protein of unknown function (DUF2789) 1 74 1.0E-28 T 28-03-2018 IPR021250 Protein of unknown function DUF2789 SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 22 319 3.2E-110 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 23 322 1.1E-97 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 SUPERFAMILY SSF53335 286 311 4.14E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 SUPERFAMILY SSF53335 21 229 4.14E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 Gene3D G3DSA:3.40.50.150 5 322 1.7E-19 T 28-03-2018 SmaCSM2_RS21540 853a5c9169d006418a37b1fb412a9e02 324 PIRSF PIRSF018005 2 324 4.2E-110 T 28-03-2018 IPR017804 Methyltransferase EgtD-like SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 Gene3D G3DSA:3.30.700.10 7 146 2.9E-26 T 28-03-2018 SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 27 6.7E-12 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 Pfam PF00114 Pilin (bacterial filament) 35 145 3.3E-14 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 SUPERFAMILY SSF54523 7 145 2.46E-23 T 28-03-2018 SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS16935 ff36e7d36f2ceb0f48888c62483903f9 149 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 1.1E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS11280 b2cebb83ed0878f216de5a4bcf313199 417 Pfam PF04966 Carbohydrate-selective porin, OprB family 51 416 6.8E-78 T 28-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 SUPERFAMILY SSF52833 10 111 9.68E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 1.5E-12 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 Gene3D G3DSA:1.20.1050.10 97 208 1.2E-16 T 28-03-2018 SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 Gene3D G3DSA:3.40.30.10 2 96 3.8E-22 T 28-03-2018 SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 SUPERFAMILY SSF47616 82 206 3.13E-24 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS07150 8b70a031d17790456723d4021acfe992 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 193 1.8E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS21080 18de95ba53874be518f704dd58b4efd4 185 Pfam PF11659 Protein of unknown function (DUF3261) 47 178 6.6E-38 T 28-03-2018 IPR021675 Protein of unknown function DUF3261 SmaCSM2_RS12095 b7846b940f1a162dc0e19cc14465580d 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 133 2.6E-27 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS15325 0b9f9d5f3fb724b00a5e6feea73d59ea 280 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 8 280 44.823 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SmaCSM2_RS15325 0b9f9d5f3fb724b00a5e6feea73d59ea 280 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 278 1.1E-61 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SmaCSM2_RS15325 0b9f9d5f3fb724b00a5e6feea73d59ea 280 Pfam PF02666 Phosphatidylserine decarboxylase 61 277 7.2E-54 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SmaCSM2_RS15875 f7e154248c336a54dbe2c4c7f226b813 214 Pfam PF00149 Calcineurin-like phosphoesterase 30 119 2.1E-5 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS15875 f7e154248c336a54dbe2c4c7f226b813 214 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 10 209 4.5E-55 T 28-03-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated SmaCSM2_RS15875 f7e154248c336a54dbe2c4c7f226b813 214 Gene3D G3DSA:3.60.21.10 28 201 5.6E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS15875 f7e154248c336a54dbe2c4c7f226b813 214 PIRSF PIRSF000887 7 210 7.4E-47 T 28-03-2018 IPR024173 Phosphoesterase, MJ0037 SmaCSM2_RS15875 f7e154248c336a54dbe2c4c7f226b813 214 SUPERFAMILY SSF56300 30 163 1.35E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS10065 1e98f127018e3ed05321662e134b53b1 338 Gene3D G3DSA:3.30.1330.60 115 304 4.2E-40 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS10065 1e98f127018e3ed05321662e134b53b1 338 Pfam PF00691 OmpA family 168 266 1.1E-19 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS10065 1e98f127018e3ed05321662e134b53b1 338 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 56 5.8E-22 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain SmaCSM2_RS10065 1e98f127018e3ed05321662e134b53b1 338 SUPERFAMILY SSF103088 142 272 6.8E-32 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS02670 1b9e5c99efd8cf37f424984ee51efaeb 269 Pfam PF05050 Methyltransferase FkbM domain 76 209 1.1E-11 T 28-03-2018 IPR006342 Methyltransferase FkbM SmaCSM2_RS02670 1b9e5c99efd8cf37f424984ee51efaeb 269 SUPERFAMILY SSF53335 50 226 9.69E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02670 1b9e5c99efd8cf37f424984ee51efaeb 269 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 73 202 1.9E-26 T 28-03-2018 IPR006342 Methyltransferase FkbM SmaCSM2_RS02670 1b9e5c99efd8cf37f424984ee51efaeb 269 Gene3D G3DSA:3.40.50.150 56 247 2.8E-30 T 28-03-2018 SmaCSM2_RS03215 569e46dba9fe9b59fc74d151112fca2f 262 Pfam PF05742 Transport and Golgi organisation 2 1 248 3.3E-58 T 28-03-2018 IPR008551 Transport and Golgi organisation protein 2 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 Gene3D G3DSA:1.10.10.10 136 245 5.7E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 SMART SM00862 162 238 2.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 SMART SM00448 15 125 3.2E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 SUPERFAMILY SSF52172 5 137 1.24E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 Gene3D G3DSA:3.40.50.2300 2 135 4.5E-34 T 28-03-2018 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 SUPERFAMILY SSF46894 139 239 8.79E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 Pfam PF00072 Response regulator receiver domain 17 125 1.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16795 b853bf70861b704bd2a50e91855ca9a7 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 238 1.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 271 287 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PIRSF PIRSF001336 1 626 4.4E-240 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 2 625 42.192 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 SUPERFAMILY SSF50621 448 565 3.03E-7 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 Gene3D G3DSA:3.20.20.10 80 340 9.3E-37 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 120 132 3.5E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 236 249 3.5E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 535 548 3.5E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 97 115 3.5E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 330 349 3.5E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 TIGRFAM TIGR01273 speA: arginine decarboxylase 4 624 5.2E-262 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 169 190 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 193 215 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 457 478 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 482 507 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 65 80 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 143 158 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 89 103 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 535 556 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 PRINTS PR01180 Arginine decarboxylase signature 320 337 1.3E-68 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 SUPERFAMILY SSF51419 65 342 8.04E-62 T 28-03-2018 IPR029066 PLP-binding barrel SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 Gene3D G3DSA:2.40.37.10 385 572 1.3E-60 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 Gene3D G3DSA:2.40.37.10 1 79 2.5E-14 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SmaCSM2_RS19930 3444f8b67340baba7033f84ddb4e199b 629 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 78 340 7.6E-44 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 18 683 39.533 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF56784 438 562 8.24E-39 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF56784 298 322 8.24E-39 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF56784 357 407 8.24E-39 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 312 318 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Pfam PF00702 haloacid dehalogenase-like hydrolase 306 533 6.7E-35 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF81653 122 212 2.75E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 1.7E-22 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 538 1.7E-22 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 554 1.7E-22 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 1.7E-22 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 476 1.7E-22 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF81665 213 304 2.88E-6 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 SUPERFAMILY SSF81665 43 108 2.88E-6 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Gene3D G3DSA:3.40.50.1000 446 576 3.8E-33 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Gene3D G3DSA:3.40.1110.10 321 445 1.3E-22 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 372 609 1.2E-42 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 78 348 1.5E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 679 4.1E-291 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Gene3D G3DSA:2.70.150.10 9 213 3.5E-25 T 28-03-2018 SmaCSM2_RS01645 87e35151f39ab4e280271042f8e08976 685 Pfam PF00122 E1-E2 ATPase 123 287 3.8E-33 T 28-03-2018 SmaCSM2_RS12275 e34d0ff6387a7455a6779bc62929b51c 299 Pfam PF00639 PPIC-type PPIASE domain 150 243 8.0E-16 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SmaCSM2_RS12275 e34d0ff6387a7455a6779bc62929b51c 299 SUPERFAMILY SSF109998 47 158 7.06E-12 T 28-03-2018 IPR027304 Trigger factor/SurA domain SmaCSM2_RS12275 e34d0ff6387a7455a6779bc62929b51c 299 SUPERFAMILY SSF54534 136 242 4.19E-21 T 28-03-2018 SmaCSM2_RS12275 e34d0ff6387a7455a6779bc62929b51c 299 Gene3D G3DSA:3.10.50.40 135 270 4.3E-24 T 28-03-2018 SmaCSM2_RS19720 22344b4e42d36576e6875d1df791b620 160 SUPERFAMILY SSF55729 5 152 1.92E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS19720 22344b4e42d36576e6875d1df791b620 160 Pfam PF00583 Acetyltransferase (GNAT) family 46 137 2.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS19720 22344b4e42d36576e6875d1df791b620 160 Gene3D G3DSA:3.40.630.30 2 159 1.5E-29 T 28-03-2018 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 Gene3D G3DSA:1.10.10.10 129 207 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 203 2.5E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 Gene3D G3DSA:1.10.1740.10 27 128 2.0E-22 T 28-03-2018 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 Pfam PF04545 Sigma-70, region 4 154 203 3.3E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 Pfam PF04542 Sigma-70 region 2 50 116 6.4E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 SUPERFAMILY SSF88946 31 131 2.43E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS08800 bb193cc22ffd61789fcdaf0e79f786ea 207 SUPERFAMILY SSF88659 132 205 1.38E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12565 77080a22f36c8bd9bffac911a7e9fb4b 218 Gene3D G3DSA:1.10.10.60 61 151 2.2E-7 T 28-03-2018 SmaCSM2_RS12565 77080a22f36c8bd9bffac911a7e9fb4b 218 Gene3D G3DSA:1.10.10.60 3 60 2.7E-12 T 28-03-2018 SmaCSM2_RS12565 77080a22f36c8bd9bffac911a7e9fb4b 218 SUPERFAMILY SSF46689 22 82 7.83E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12565 77080a22f36c8bd9bffac911a7e9fb4b 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 73 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 154 183 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 PIRSF PIRSF001553 1 291 2.7E-130 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 9.0E-37 T 28-03-2018 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 9.0E-37 T 28-03-2018 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 9.0E-37 T 28-03-2018 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 9.0E-37 T 28-03-2018 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 Pfam PF00549 CoA-ligase 153 274 3.2E-19 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 SUPERFAMILY SSF52210 125 290 8.11E-56 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 289 6.5E-139 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 Gene3D G3DSA:3.40.50.261 122 291 1.9E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 Gene3D G3DSA:3.40.50.720 1 121 3.2E-45 T 28-03-2018 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 Pfam PF02629 CoA binding domain 6 99 6.2E-31 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 SUPERFAMILY SSF51735 1 124 8.4E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 43.312 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SmaCSM2_RS16900 c167f50bb3d7a7167fe939de30f79c4e 291 SMART SM00881 4 100 5.9E-37 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SmaCSM2_RS08770 57b84d706b609085da0f8c973b51a49e 302 SUPERFAMILY SSF53613 25 284 5.14E-58 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS08770 57b84d706b609085da0f8c973b51a49e 302 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 24 301 1.8E-52 T 28-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SmaCSM2_RS08770 57b84d706b609085da0f8c973b51a49e 302 Pfam PF08543 Phosphomethylpyrimidine kinase 125 276 1.2E-19 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SmaCSM2_RS08770 57b84d706b609085da0f8c973b51a49e 302 Gene3D G3DSA:3.40.1190.20 20 283 5.3E-51 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 77 2.1E-12 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 SUPERFAMILY SSF47616 84 198 9.05E-17 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 Pfam PF13410 Glutathione S-transferase, C-terminal domain 133 186 2.9E-7 T 28-03-2018 SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 SUPERFAMILY SSF52833 5 87 1.06E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 Gene3D G3DSA:3.40.30.10 1 80 2.4E-20 T 28-03-2018 SmaCSM2_RS07120 75c9cf20a87bd62cb80d4068145616ff 206 Gene3D G3DSA:1.20.1050.10 81 204 1.1E-14 T 28-03-2018 SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 SUPERFAMILY SSF53901 213 400 2.67E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 Gene3D G3DSA:3.40.47.10 4 257 2.7E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 SMART SM00825 Beta-ketoacyl synthase 4 402 3.7E-11 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 Gene3D G3DSA:3.40.47.10 258 401 1.2E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 6.9E-25 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 SUPERFAMILY SSF53901 1 251 7.41E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS02470 cfe9a964b7ea765a6b89f3f4e54d4f6b 402 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 5.2E-47 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SmaCSM2_RS19145 20d0012e93a546118cfc1227ad96bb4d 259 Pfam PF12872 OST-HTH/LOTUS domain 184 250 2.6E-14 T 28-03-2018 IPR025605 OST-HTH/LOTUS domain SmaCSM2_RS19145 20d0012e93a546118cfc1227ad96bb4d 259 Pfam PF01936 NYN domain 7 142 1.8E-32 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type SmaCSM2_RS19145 20d0012e93a546118cfc1227ad96bb4d 259 Gene3D G3DSA:3.40.50.1010 1 144 3.7E-22 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS02070 58d47d7eb4c6f76b6172fa9a50d569e3 461 Pfam PF13289 SIR2-like domain 149 253 7.5E-18 T 28-03-2018 SmaCSM2_RS01445 c87da7a1c781c35769fb94f5591d0910 440 Pfam PF12704 MacB-like periplasmic core domain 74 279 5.8E-15 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS01445 c87da7a1c781c35769fb94f5591d0910 440 Pfam PF02687 FtsX-like permease family 338 431 2.6E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS08870 e331dce02d39bf53127d2904678b4b9c 289 Gene3D G3DSA:3.30.2350.10 77 285 1.7E-44 T 28-03-2018 SmaCSM2_RS08870 e331dce02d39bf53127d2904678b4b9c 289 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 125 139 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS08870 e331dce02d39bf53127d2904678b4b9c 289 Pfam PF00849 RNA pseudouridylate synthase 86 232 1.5E-24 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS08870 e331dce02d39bf53127d2904678b4b9c 289 SUPERFAMILY SSF55120 70 282 3.06E-51 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 SMART SM00382 122 248 9.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 2.9E-157 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 SUPERFAMILY SSF52540 5 336 2.66E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 Gene3D G3DSA:3.40.50.300 274 345 2.0E-12 T 28-03-2018 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 Gene3D G3DSA:3.40.50.300 117 273 5.4E-27 T 28-03-2018 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 Gene3D G3DSA:3.30.450.90 1 100 1.4E-24 T 28-03-2018 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS04975 1b9b40053dd5bdcf7d19db8e12a228a5 345 Pfam PF00437 Type II/IV secretion system protein 12 269 1.3E-47 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS17365 62b50c1bf8cb993a824d285d89f21c1d 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 126 3.5E-51 T 28-03-2018 IPR006056 RidA family SmaCSM2_RS17365 62b50c1bf8cb993a824d285d89f21c1d 128 Pfam PF01042 Endoribonuclease L-PSP 9 126 3.5E-41 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SmaCSM2_RS17365 62b50c1bf8cb993a824d285d89f21c1d 128 SUPERFAMILY SSF55298 1 127 1.12E-44 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS17365 62b50c1bf8cb993a824d285d89f21c1d 128 Gene3D G3DSA:3.30.1330.40 1 128 7.6E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS05625 641b811967d6c3a5195987bc0e332f2b 264 Pfam PF12697 Alpha/beta hydrolase family 33 244 3.0E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS05625 641b811967d6c3a5195987bc0e332f2b 264 SUPERFAMILY SSF53474 163 248 1.33E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05625 641b811967d6c3a5195987bc0e332f2b 264 SUPERFAMILY SSF53474 25 122 1.33E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05625 641b811967d6c3a5195987bc0e332f2b 264 Gene3D G3DSA:3.40.50.1820 3 251 2.1E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS13660 d8bb5a92c8b4fce80fecd7070a63ac0c 163 TIGRFAM TIGR01837 PHA_granule_1: poly(hydroxyalkanoate) granule-associated protein 26 141 2.7E-36 T 28-03-2018 IPR008769 Poly granule associated SmaCSM2_RS13660 d8bb5a92c8b4fce80fecd7070a63ac0c 163 Gene3D G3DSA:1.20.5.1070 79 149 1.1E-4 T 28-03-2018 SmaCSM2_RS13660 d8bb5a92c8b4fce80fecd7070a63ac0c 163 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 18 141 2.0E-43 T 28-03-2018 IPR008769 Poly granule associated SmaCSM2_RS19945 d42be2b68898a045034a1f74053a6698 219 SUPERFAMILY SSF56112 32 178 1.23E-18 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS19945 d42be2b68898a045034a1f74053a6698 219 Pfam PF01163 RIO1 family 54 179 1.4E-4 T 28-03-2018 SmaCSM2_RS19945 d42be2b68898a045034a1f74053a6698 219 Gene3D G3DSA:3.90.1200.10 58 215 1.8E-14 T 28-03-2018 SmaCSM2_RS12170 53e840ed6fa7c0140c805942db981a3b 175 Gene3D G3DSA:3.30.1360.100 91 163 4.1E-8 T 28-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain SmaCSM2_RS12170 53e840ed6fa7c0140c805942db981a3b 175 Pfam PF04612 Type II secretion system (T2SS), protein M 14 156 1.3E-21 T 28-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 SmaCSM2_RS03550 a66ec712472fe1fa23f594a0505cc183 127 Gene3D G3DSA:2.60.40.1470 2 127 5.3E-42 T 28-03-2018 IPR007474 ApaG domain SmaCSM2_RS03550 a66ec712472fe1fa23f594a0505cc183 127 Pfam PF04379 ApaG domain 20 104 7.7E-34 T 28-03-2018 IPR007474 ApaG domain SmaCSM2_RS03550 a66ec712472fe1fa23f594a0505cc183 127 Hamap MF_00791 Protein ApaG [apaG]. 2 127 32.123 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG SmaCSM2_RS03550 a66ec712472fe1fa23f594a0505cc183 127 SUPERFAMILY SSF110069 8 127 6.67E-47 T 28-03-2018 IPR007474 ApaG domain SmaCSM2_RS00120 53c36640e4c10200bfa345ad3228f4cb 473 Gene3D G3DSA:3.40.710.10 263 419 0.0017 T 28-03-2018 SmaCSM2_RS00120 53c36640e4c10200bfa345ad3228f4cb 473 SUPERFAMILY SSF52540 358 467 4.87E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00120 53c36640e4c10200bfa345ad3228f4cb 473 SUPERFAMILY SSF52540 15 290 4.87E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00120 53c36640e4c10200bfa345ad3228f4cb 473 Pfam PF13245 AAA domain 14 168 7.3E-13 T 28-03-2018 SmaCSM2_RS00120 53c36640e4c10200bfa345ad3228f4cb 473 Gene3D G3DSA:3.40.50.300 11 192 5.9E-23 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SMART SM00322 305 369 0.0013 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SMART SM00322 234 297 18.0 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:3.30.1480.10 1 132 2.9E-43 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Pfam PF08529 NusA N-terminal domain 4 128 1.8E-35 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:3.30.300.20 282 352 6.8E-14 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SMART SM00316 137 204 9.2E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:1.10.150.20 356 425 2.4E-13 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:1.10.150.20 432 495 1.7E-10 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF54814 283 346 8.5E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Pfam PF14520 Helix-hairpin-helix domain 436 492 7.2E-6 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Pfam PF14520 Helix-hairpin-helix domain 370 416 0.0016 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF54814 205 282 2.94E-29 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF50249 135 203 2.03E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 414 29.494 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF47794 359 419 2.2E-16 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF69705 1 130 1.7E-36 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Pfam PF13184 NusA-like KH domain 234 301 7.6E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 347 2.9E-125 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:2.40.50.140 133 202 3.2E-14 T 28-03-2018 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Gene3D G3DSA:3.30.300.20 203 280 6.5E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 SUPERFAMILY SSF47794 429 493 6.91E-9 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 444 494 7.4E-14 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 369 418 1.1E-21 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication SmaCSM2_RS15090 4b5139a46af8f490a7ffb695bfdea20e 503 Pfam PF00575 S1 RNA binding domain 135 199 2.7E-7 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS03580 1c890aecb72415700a609ffa3adac8f6 184 Pfam PF01923 Cobalamin adenosyltransferase 8 165 2.8E-58 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SmaCSM2_RS03580 1c890aecb72415700a609ffa3adac8f6 184 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 178 1.6E-58 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SmaCSM2_RS03580 1c890aecb72415700a609ffa3adac8f6 184 SUPERFAMILY SSF89028 7 178 1.35E-59 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SmaCSM2_RS03580 1c890aecb72415700a609ffa3adac8f6 184 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 24 177 2.0E-46 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SmaCSM2_RS03580 1c890aecb72415700a609ffa3adac8f6 184 Gene3D G3DSA:1.20.1200.10 17 183 2.3E-63 T 28-03-2018 SmaCSM2_RS10855 f7ea237a28c1b3f94fcf015e499c9585 127 Pfam PF04234 CopC domain 29 126 4.7E-22 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 SmaCSM2_RS10855 f7ea237a28c1b3f94fcf015e499c9585 127 Gene3D G3DSA:2.60.40.1220 28 127 2.3E-22 T 28-03-2018 SmaCSM2_RS10855 f7ea237a28c1b3f94fcf015e499c9585 127 SUPERFAMILY SSF81296 28 126 5.46E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set SmaCSM2_RS21670 8ee1d2807a42a86886496fb7431cc02e 522 Pfam PF02646 RmuC family 201 496 1.5E-82 T 28-03-2018 IPR003798 DNA recombination RmuC SmaCSM2_RS21670 8ee1d2807a42a86886496fb7431cc02e 522 Gene3D G3DSA:1.10.287.620 35 170 6.5E-5 T 28-03-2018 SmaCSM2_RS21670 8ee1d2807a42a86886496fb7431cc02e 522 Gene3D G3DSA:1.20.5.340 212 361 1.2E-13 T 28-03-2018 SmaCSM2_RS16875 1e7f9fe0c41f12a1d64220050b3fcdd2 256 Gene3D G3DSA:3.60.140.10 2 256 3.3E-82 T 28-03-2018 SmaCSM2_RS16875 1e7f9fe0c41f12a1d64220050b3fcdd2 256 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 23 253 4.9E-69 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SmaCSM2_RS16875 1e7f9fe0c41f12a1d64220050b3fcdd2 256 SUPERFAMILY SSF64438 6 254 1.03E-69 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic SmaCSM2_RS16875 1e7f9fe0c41f12a1d64220050b3fcdd2 256 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 37 254 1.1E-48 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 SMART SM00304 391 443 15.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 SMART SM00304 210 262 4.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 SMART SM00283 444 691 1.5E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 Pfam PF00672 HAMP domain 210 258 3.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 Gene3D G3DSA:1.10.287.950 315 500 1.8E-22 T 28-03-2018 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 Gene3D G3DSA:1.10.287.950 501 695 1.6E-47 T 28-03-2018 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 SUPERFAMILY SSF158472 210 260 1.96E-8 T 28-03-2018 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 504 658 2.4E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS21005 98feed2ed9a576bf306fbea38feae398 706 SUPERFAMILY SSF58104 414 692 1.06E-69 T 28-03-2018 SmaCSM2_RS02520 0c6caf74208554a405d35028069748e3 192 SUPERFAMILY SSF53254 3 178 7.28E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS02520 0c6caf74208554a405d35028069748e3 192 SMART SM00855 2 148 8.9E-4 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS02520 0c6caf74208554a405d35028069748e3 192 Gene3D G3DSA:3.40.50.1240 4 190 5.4E-29 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS02520 0c6caf74208554a405d35028069748e3 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 31 178 6.4E-31 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SUPERFAMILY SSF158472 215 262 1.12E-7 T 28-03-2018 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Gene3D G3DSA:1.10.287.1060 462 549 0.027 T 28-03-2018 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Gene3D G3DSA:1.10.287.950 550 742 7.0E-48 T 28-03-2018 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Pfam PF00672 HAMP domain 213 262 6.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 186 8.1E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SMART SM00304 213 265 4.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SMART SM00304 438 490 18.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 551 705 8.9E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Gene3D G3DSA:3.30.450.20 260 406 1.0E-11 T 28-03-2018 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SUPERFAMILY SSF58104 458 738 1.09E-70 T 28-03-2018 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 Gene3D G3DSA:1.20.120.30 25 187 5.4E-15 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SMART SM00283 491 738 2.0E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 SmaCSM2_RS10015 c8f3d58c7f10bf88cbc74a0758265e5d 792 SUPERFAMILY SSF55785 259 386 1.15E-6 T 28-03-2018 IPR000014 PAS domain SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 Gene3D G3DSA:1.10.10.10 7 88 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 SUPERFAMILY SSF46785 8 116 9.67E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 Gene3D G3DSA:3.40.190.10 93 181 4.4E-21 T 28-03-2018 SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 Gene3D G3DSA:3.40.190.10 182 269 1.2E-22 T 28-03-2018 SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 SUPERFAMILY SSF53850 94 299 2.64E-46 T 28-03-2018 SmaCSM2_RS09125 c8c42b2c51a1c1a748d04c7ff7cc3004 307 Pfam PF03466 LysR substrate binding domain 92 295 2.0E-44 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS20725 08b71d2c83da224d9b6023c264e109eb 176 Gene3D G3DSA:2.160.10.10 2 175 2.3E-43 T 28-03-2018 SmaCSM2_RS20725 08b71d2c83da224d9b6023c264e109eb 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 97 130 6.6E-7 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS20725 08b71d2c83da224d9b6023c264e109eb 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 46 2.9E-5 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS20725 08b71d2c83da224d9b6023c264e109eb 176 SUPERFAMILY SSF51161 3 174 5.82E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 36 406 1.2E-119 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 27 440 39.576 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 Pfam PF01566 Natural resistance-associated macrophage protein 56 412 4.1E-132 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 115 141 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 168 189 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 352 369 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 143 162 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 220 243 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 384 403 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS12585 e859037b9a5cf3d43e3d2fbdf552c584 443 PRINTS PR00447 Natural resistance-associated macrophage protein signature 324 343 2.7E-58 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SmaCSM2_RS11025 3b5301554de20fa86d11657218bdbe4b 342 Gene3D G3DSA:1.10.10.10 67 340 3.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13865 52819db0c3de7467f9b8bf2159f3fded 161 SUPERFAMILY SSF55729 8 142 1.72E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS13865 52819db0c3de7467f9b8bf2159f3fded 161 Pfam PF00583 Acetyltransferase (GNAT) family 28 140 8.7E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS13865 52819db0c3de7467f9b8bf2159f3fded 161 Gene3D G3DSA:3.40.630.30 2 147 5.8E-24 T 28-03-2018 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 75 2.1E-21 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 Pfam PF01380 SIS domain 130 256 5.8E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 SUPERFAMILY SSF53697 106 270 4.45E-25 T 28-03-2018 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 Gene3D G3DSA:3.40.50.10490 122 256 1.5E-18 T 28-03-2018 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 SUPERFAMILY SSF46689 3 74 6.45E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS01920 4ddc14a20ab3ccb0dac70c0a4bcdde67 282 Gene3D G3DSA:1.10.10.10 3 121 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 SUPERFAMILY SSF46689 246 296 4.21E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 Gene3D G3DSA:1.10.10.60 250 300 7.2E-11 T 28-03-2018 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 SUPERFAMILY SSF46689 195 243 1.31E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 Pfam PF06719 AraC-type transcriptional regulator N-terminus 31 180 1.3E-42 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 197 238 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 Pfam PF12833 Helix-turn-helix domain 215 290 1.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 SMART SM00342 209 292 4.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS09220 ba6babfac5caf0fe8fd1ade070c7a1f6 314 Gene3D G3DSA:1.10.10.60 68 249 2.8E-12 T 28-03-2018 SmaCSM2_RS19030 22d51b2320fe1d951ac223b7ee5b26fb 268 Pfam PF00535 Glycosyl transferase family 2 14 133 2.1E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS19030 22d51b2320fe1d951ac223b7ee5b26fb 268 SUPERFAMILY SSF53448 8 153 4.02E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS19030 22d51b2320fe1d951ac223b7ee5b26fb 268 Gene3D G3DSA:3.90.550.10 2 206 6.1E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS09275 fe8a37f7c605f30d76002cdb4dfe0141 183 Pfam PF00583 Acetyltransferase (GNAT) family 57 142 8.6E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS09275 fe8a37f7c605f30d76002cdb4dfe0141 183 Gene3D G3DSA:3.40.630.30 6 160 6.2E-20 T 28-03-2018 SmaCSM2_RS09275 fe8a37f7c605f30d76002cdb4dfe0141 183 SUPERFAMILY SSF55729 13 164 6.0E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS15330 1f17d795816142ba11008937228829e3 115 Gene3D G3DSA:3.30.70.970 1 110 2.0E-22 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain SmaCSM2_RS15330 1f17d795816142ba11008937228829e3 115 SUPERFAMILY SSF89946 22 105 4.18E-6 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain SmaCSM2_RS15330 1f17d795816142ba11008937228829e3 115 Pfam PF06877 Regulator of ribonuclease activity B 4 108 2.4E-19 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 Gene3D G3DSA:3.40.190.10 92 169 3.4E-10 T 28-03-2018 SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 Pfam PF03466 LysR substrate binding domain 90 290 7.8E-31 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 Gene3D G3DSA:3.40.190.10 170 263 2.1E-16 T 28-03-2018 SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 SUPERFAMILY SSF46785 5 114 1.44E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 SUPERFAMILY SSF53850 92 295 1.28E-34 T 28-03-2018 SmaCSM2_RS07445 168c1f2a429e51456bcd75e05bdae953 301 Gene3D G3DSA:1.10.10.10 2 83 9.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11460 638a44d83468a66364c58fb44483cae8 333 ProSitePatterns PS00893 Nudix box signature. 189 210 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS11460 638a44d83468a66364c58fb44483cae8 333 Gene3D G3DSA:3.90.79.10 34 328 7.9E-9 T 28-03-2018 SmaCSM2_RS11460 638a44d83468a66364c58fb44483cae8 333 SUPERFAMILY SSF55811 148 226 3.66E-8 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS17260 591ca590f3769816e79377af9ee7d274 309 Pfam PF01882 Protein of unknown function DUF58 57 141 2.5E-20 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SmaCSM2_RS17260 591ca590f3769816e79377af9ee7d274 309 Gene3D G3DSA:3.40.50.410 69 293 1.2E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 Gene3D G3DSA:1.20.1250.20 282 473 6.7E-17 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 Gene3D G3DSA:1.20.1250.20 34 220 1.5E-27 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 SUPERFAMILY SSF103473 19 223 9.42E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 SUPERFAMILY SSF103473 270 471 9.42E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 166 190 1.8E-8 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 191 215 1.8E-8 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 423 442 1.8E-8 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 156 1.8E-8 T 28-03-2018 SmaCSM2_RS04945 0398d404f679c094dbc7cf313d495d1d 473 Pfam PF07690 Major Facilitator Superfamily 51 342 2.6E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS08600 c7a54c8c2a091d5ab25f8a1fde98cc67 256 SUPERFAMILY SSF51735 9 198 7.94E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS08600 c7a54c8c2a091d5ab25f8a1fde98cc67 256 Gene3D G3DSA:3.40.50.720 7 208 5.7E-26 T 28-03-2018 SmaCSM2_RS08600 c7a54c8c2a091d5ab25f8a1fde98cc67 256 Pfam PF00106 short chain dehydrogenase 9 185 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS04055 3febc3a9cccd380aecdc78ef6bf11aca 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.502 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid SmaCSM2_RS04055 3febc3a9cccd380aecdc78ef6bf11aca 101 Gene3D G3DSA:4.10.830.10 1 101 5.1E-32 T 28-03-2018 SmaCSM2_RS04055 3febc3a9cccd380aecdc78ef6bf11aca 101 SUPERFAMILY SSF57716 2 101 5.13E-35 T 28-03-2018 SmaCSM2_RS04055 3febc3a9cccd380aecdc78ef6bf11aca 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 2.5E-23 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 10 170 3.5E-40 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 263 3.3E-23 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 Gene3D G3DSA:3.40.50.1010 8 186 5.8E-56 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 SMART SM00475 5 270 4.5E-73 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 SUPERFAMILY SSF47807 173 292 8.37E-23 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 Gene3D G3DSA:1.10.150.20 187 268 2.5E-19 T 28-03-2018 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 SMART SM00279 175 210 6.0E-10 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SmaCSM2_RS03700 af514e3e59975bae5c1dec971ed2e7c8 316 SUPERFAMILY SSF88723 8 163 9.32E-41 T 28-03-2018 IPR029060 PIN domain-like SmaCSM2_RS04705 824de6a53af1a3fc04a82f6ed5988602 233 SUPERFAMILY SSF55073 42 198 2.2E-18 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS04705 824de6a53af1a3fc04a82f6ed5988602 233 Gene3D G3DSA:3.30.70.1230 33 233 4.4E-13 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SmaCSM2_RS13435 a6e1c3a75183b1fd1020c2541cf01843 348 Pfam PF04335 VirB8 protein 20 240 1.9E-55 T 28-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 SmaCSM2_RS13435 a6e1c3a75183b1fd1020c2541cf01843 348 SUPERFAMILY SSF54427 94 240 2.94E-31 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 Gene3D G3DSA:2.170.130.10 28 169 2.0E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 164 2.7E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 Gene3D G3DSA:2.40.170.20 170 941 8.6E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 SUPERFAMILY SSF56935 672 941 7.94E-100 T 28-03-2018 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 SUPERFAMILY SSF56935 368 432 7.94E-100 T 28-03-2018 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 SUPERFAMILY SSF56935 480 629 7.94E-100 T 28-03-2018 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 SUPERFAMILY SSF56935 37 229 7.94E-100 T 28-03-2018 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 SUPERFAMILY SSF56935 291 339 7.94E-100 T 28-03-2018 SmaCSM2_RS01440 5a85efd111d75761eb7bf85799fa19d4 941 Pfam PF00593 TonB dependent receptor 365 938 3.0E-44 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15765 4e6f777ded58383ffff7bb1421f36eef 97 Pfam PF03692 Putative zinc- or iron-chelating domain 2 72 4.3E-9 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein SmaCSM2_RS08560 f6ed68722ec3a2ccab8aadc257fd46dc 371 SUPERFAMILY SSF50956 55 370 1.7E-34 T 28-03-2018 SmaCSM2_RS08560 f6ed68722ec3a2ccab8aadc257fd46dc 371 Pfam PF01436 NHL repeat 109 134 1.2E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 SmaCSM2_RS08560 f6ed68722ec3a2ccab8aadc257fd46dc 371 Gene3D G3DSA:2.120.10.30 31 367 1.2E-18 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS14655 591a331c1887441fdf7e21f6514f76a8 409 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 367 399 6.3E-8 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SmaCSM2_RS14655 591a331c1887441fdf7e21f6514f76a8 409 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 286 408 28.388 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 SmaCSM2_RS14655 591a331c1887441fdf7e21f6514f76a8 409 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 290 399 3.2E-42 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 SmaCSM2_RS14655 591a331c1887441fdf7e21f6514f76a8 409 SUPERFAMILY SSF109635 276 368 1.96E-28 T 28-03-2018 SmaCSM2_RS14655 591a331c1887441fdf7e21f6514f76a8 409 SUPERFAMILY SSF57716 369 407 3.71E-6 T 28-03-2018 SmaCSM2_RS03695 15611763352d5191254bd9f13c92f2bd 184 Pfam PF00293 NUDIX domain 38 104 2.3E-9 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS03695 15611763352d5191254bd9f13c92f2bd 184 Gene3D G3DSA:3.90.79.10 4 180 2.6E-25 T 28-03-2018 SmaCSM2_RS03695 15611763352d5191254bd9f13c92f2bd 184 SUPERFAMILY SSF55811 22 178 1.49E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 Gene3D G3DSA:3.90.1180.10 1 142 1.2E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 Pfam PF00572 Ribosomal protein L13 15 138 7.8E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 PIRSF PIRSF002181 1 142 6.5E-51 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.467 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 SUPERFAMILY SSF52161 1 140 2.62E-59 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS19655 4d857f2d10a0dd025869e37ac7445f83 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 4.6E-64 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 SUPERFAMILY SSF48498 92 199 3.51E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 Gene3D G3DSA:1.10.10.60 55 87 1.1E-11 T 28-03-2018 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 Gene3D G3DSA:1.10.357.10 88 200 6.1E-5 T 28-03-2018 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 SUPERFAMILY SSF46689 8 83 3.44E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS18875 07ee6c4bb5570c365039c17476023772 209 Gene3D G3DSA:1.10.10.60 1 54 1.1E-18 T 28-03-2018 SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 304 2.8E-88 T 28-03-2018 SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 Gene3D G3DSA:3.40.50.150 106 306 2.9E-30 T 28-03-2018 SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 297 8.5E-63 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 304 30.424 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 SUPERFAMILY SSF53335 71 303 1.29E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS19350 2c15caea3b9cdb2e599f7187694fee96 306 PIRSF PIRSF000401 1 306 3.5E-86 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SmaCSM2_RS08385 6623d3072e8e0483a885e0724a765f87 249 SMART SM00014 112 221 8.4E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS08385 6623d3072e8e0483a885e0724a765f87 249 SUPERFAMILY SSF48317 42 234 6.54E-39 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS08385 6623d3072e8e0483a885e0724a765f87 249 Gene3D G3DSA:1.20.144.10 11 244 1.8E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS08385 6623d3072e8e0483a885e0724a765f87 249 Pfam PF01569 PAP2 superfamily 113 226 1.8E-21 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SmaCSM2_RS01070 4bba3dcfe26b01096e007de0a29a4fac 223 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 58 152 8.3E-8 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SmaCSM2_RS01070 4bba3dcfe26b01096e007de0a29a4fac 223 SUPERFAMILY SSF53474 16 218 4.15E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS01070 4bba3dcfe26b01096e007de0a29a4fac 223 Gene3D G3DSA:3.40.50.1820 10 222 2.7E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 Gene3D G3DSA:3.40.50.620 1 176 3.4E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 Hamap MF_00158 Pantothenate synthetase [panC]. 3 279 38.246 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 Pfam PF02569 Pantoate-beta-alanine ligase 4 277 1.0E-96 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 SUPERFAMILY SSF52374 3 278 1.56E-100 T 28-03-2018 SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 3 277 9.0E-90 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SmaCSM2_RS08350 485915d4b6ef09749fe24661feafb882 279 Gene3D G3DSA:3.30.1300.10 178 279 1.8E-27 T 28-03-2018 SmaCSM2_RS06425 9fd182b4589ea9c891b6aa30cc28eac9 129 Pfam PF01124 MAPEG family 8 128 2.5E-24 T 28-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein SmaCSM2_RS06425 9fd182b4589ea9c891b6aa30cc28eac9 129 SUPERFAMILY SSF161084 3 129 1.18E-29 T 28-03-2018 SmaCSM2_RS06425 9fd182b4589ea9c891b6aa30cc28eac9 129 Gene3D G3DSA:1.20.120.550 1 129 2.2E-23 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 Pfam PF00067 Cytochrome P450 225 388 4.1E-27 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 Gene3D G3DSA:1.10.630.10 56 400 1.3E-35 T 28-03-2018 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 PRINTS PR00463 E-class P450 group I signature 339 349 3.1E-8 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 PRINTS PR00463 E-class P450 group I signature 305 329 3.1E-8 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 PRINTS PR00463 E-class P450 group I signature 224 250 3.1E-8 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 PRINTS PR00463 E-class P450 group I signature 349 372 3.1E-8 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS08650 ec8e03760598d86d9917e31a99b12eb6 404 SUPERFAMILY SSF48264 15 385 1.3E-34 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SmaCSM2_RS18630 cb46e15a733387e75ef9eba96cdd66b0 407 Pfam PF02687 FtsX-like permease family 314 397 4.4E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS18630 cb46e15a733387e75ef9eba96cdd66b0 407 Pfam PF12704 MacB-like periplasmic core domain 21 249 4.4E-11 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS04355 65ac01a622b9bb69349e7cf8034d3dc8 247 Pfam PF00857 Isochorismatase family 47 233 7.4E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS04355 65ac01a622b9bb69349e7cf8034d3dc8 247 SUPERFAMILY SSF52499 23 238 6.41E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS04355 65ac01a622b9bb69349e7cf8034d3dc8 247 Gene3D G3DSA:3.40.50.850 20 245 8.6E-45 T 28-03-2018 SmaCSM2_RS18035 c5f9108369ee675578c5fbd8b7846ec2 114 Gene3D G3DSA:1.20.1440.40 14 109 2.2E-13 T 28-03-2018 IPR023376 YqcC-like domain SmaCSM2_RS18035 c5f9108369ee675578c5fbd8b7846ec2 114 SUPERFAMILY SSF158452 17 111 8.5E-16 T 28-03-2018 IPR023376 YqcC-like domain SmaCSM2_RS18035 c5f9108369ee675578c5fbd8b7846ec2 114 Pfam PF04287 tRNA pseudouridine synthase C 19 108 2.6E-9 T 28-03-2018 IPR023376 YqcC-like domain SmaCSM2_RS05700 5ed51cce6196232cad23cd323f606b1b 106 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 99 4.0E-35 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit SmaCSM2_RS05700 5ed51cce6196232cad23cd323f606b1b 106 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 99 6.0E-31 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit SmaCSM2_RS05700 5ed51cce6196232cad23cd323f606b1b 106 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 20 99 3.4E-25 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein SmaCSM2_RS05700 5ed51cce6196232cad23cd323f606b1b 106 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 104 51.287 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit SmaCSM2_RS17655 981fd8d43dcb86ef28b3af635ad3ece2 195 Pfam PF01126 Heme oxygenase 13 185 4.7E-21 T 28-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SmaCSM2_RS17655 981fd8d43dcb86ef28b3af635ad3ece2 195 Gene3D G3DSA:1.20.910.10 2 192 2.1E-34 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SmaCSM2_RS17655 981fd8d43dcb86ef28b3af635ad3ece2 195 SUPERFAMILY SSF48613 10 191 4.77E-54 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SmaCSM2_RS10435 a91d8bd144bde920cd015439021b9f9a 502 SUPERFAMILY SSF53187 264 391 7.22E-14 T 28-03-2018 SmaCSM2_RS10435 a91d8bd144bde920cd015439021b9f9a 502 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 186 387 1.9E-12 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SmaCSM2_RS10435 a91d8bd144bde920cd015439021b9f9a 502 SMART SM00646 274 392 4.1E-6 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SmaCSM2_RS10435 a91d8bd144bde920cd015439021b9f9a 502 Gene3D G3DSA:3.40.630.40 162 399 1.4E-24 T 28-03-2018 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 SUPERFAMILY SSF111148 1 88 9.16E-37 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 PIRSF PIRSF029827 1 89 1.0E-40 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 Pfam PF04362 Bacterial Fe(2+) trafficking 1 87 5.7E-39 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 Gene3D G3DSA:1.10.3880.10 2 89 4.1E-37 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 77 7.0E-34 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS08480 72003fa83cfad746ce6ce5ef730b70c5 89 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.652 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 SmaCSM2_RS16510 847d5baeb57d768924d596fe744ac8c6 237 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 215 2.0E-51 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 SmaCSM2_RS16510 847d5baeb57d768924d596fe744ac8c6 237 SUPERFAMILY SSF53067 1 101 2.16E-26 T 28-03-2018 SmaCSM2_RS16510 847d5baeb57d768924d596fe744ac8c6 237 Gene3D G3DSA:3.30.420.40 1 135 1.1E-33 T 28-03-2018 SmaCSM2_RS16510 847d5baeb57d768924d596fe744ac8c6 237 SUPERFAMILY SSF53067 107 213 8.03E-19 T 28-03-2018 SmaCSM2_RS16510 847d5baeb57d768924d596fe744ac8c6 237 Pfam PF00814 Glycoprotease family 28 129 1.4E-25 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SmaCSM2_RS20235 1936b7c0342c3163dcc9704e2747a5a1 132 Gene3D G3DSA:3.10.180.10 5 131 8.7E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS20235 1936b7c0342c3163dcc9704e2747a5a1 132 SUPERFAMILY SSF54593 12 130 2.61E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS20235 1936b7c0342c3163dcc9704e2747a5a1 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 126 3.8E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 185 1.6E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 SUPERFAMILY SSF56935 661 858 2.59E-98 T 28-03-2018 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 SUPERFAMILY SSF56935 49 261 2.59E-98 T 28-03-2018 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 SUPERFAMILY SSF56935 298 622 2.59E-98 T 28-03-2018 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 Gene3D G3DSA:2.170.130.10 39 189 3.6E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 Pfam PF00593 TonB dependent receptor 375 855 3.6E-41 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09245 8dd28999fbff45396a0fc150633b7175 858 Gene3D G3DSA:2.40.170.20 190 858 3.9E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 SMART SM00563 458 574 5.1E-31 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 Pfam PF07690 Major Facilitator Superfamily 38 381 3.6E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 SUPERFAMILY SSF103473 10 426 4.71E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 Gene3D G3DSA:1.20.1250.20 3 199 1.3E-13 T 28-03-2018 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 Pfam PF01553 Acyltransferase 449 571 2.5E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 Gene3D G3DSA:1.20.1250.20 218 419 1.0E-11 T 28-03-2018 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 Gene3D G3DSA:3.40.1130.10 420 625 7.6E-43 T 28-03-2018 SmaCSM2_RS19565 4a2ad2900c28ebbd6c7f8d16dffcf93c 629 SUPERFAMILY SSF69593 417 608 4.32E-31 T 28-03-2018 SmaCSM2_RS01795 4389a242bc3be3a712fe298dea15d44b 196 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 32 175 3.0E-45 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01795 4389a242bc3be3a712fe298dea15d44b 196 SUPERFAMILY SSF110111 63 177 9.55E-45 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01795 4389a242bc3be3a712fe298dea15d44b 196 PIRSF PIRSF005413 1 192 1.3E-58 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS01795 4389a242bc3be3a712fe298dea15d44b 196 Gene3D G3DSA:2.60.370.10 60 179 7.1E-43 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 Gene3D G3DSA:2.40.30.10 2 97 1.0E-17 T 28-03-2018 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 SUPERFAMILY SSF52343 104 257 5.63E-41 T 28-03-2018 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 Pfam PF00970 Oxidoreductase FAD-binding domain 19 98 1.6E-6 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 SUPERFAMILY SSF63380 8 100 2.69E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 Pfam PF00175 Oxidoreductase NAD-binding domain 113 229 1.5E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SmaCSM2_RS14275 6384459b9593fbf74fab7eeac1a4101e 259 Gene3D G3DSA:3.40.50.80 98 259 9.2E-23 T 28-03-2018 SmaCSM2_RS21275 5507aabb1aec6724ef4c085b0a87b213 78 Pfam PF00830 Ribosomal L28 family 3 62 1.5E-27 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21275 5507aabb1aec6724ef4c085b0a87b213 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.466 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS21275 5507aabb1aec6724ef4c085b0a87b213 78 Gene3D G3DSA:2.30.170.40 2 75 2.1E-31 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21275 5507aabb1aec6724ef4c085b0a87b213 78 SUPERFAMILY SSF143800 2 77 7.06E-31 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21275 5507aabb1aec6724ef4c085b0a87b213 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.7E-26 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS12545 8389e01d81a5b002b4cc6ef47bf8a162 192 Pfam PF01613 Flavin reductase like domain 37 180 8.3E-33 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS12545 8389e01d81a5b002b4cc6ef47bf8a162 192 SMART SM00903 36 181 2.1E-44 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS12545 8389e01d81a5b002b4cc6ef47bf8a162 192 SUPERFAMILY SSF50475 27 179 3.19E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS12545 8389e01d81a5b002b4cc6ef47bf8a162 192 Gene3D G3DSA:2.30.110.10 24 186 2.5E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS05870 46ab4391980353458555fcce01b830f5 148 Pfam PF04314 Copper chaperone PCu(A)C 30 137 4.5E-29 T 28-03-2018 IPR007410 Copper chaperone PCuAC SmaCSM2_RS05870 46ab4391980353458555fcce01b830f5 148 SUPERFAMILY SSF110087 2 147 3.66E-39 T 28-03-2018 IPR007410 Copper chaperone PCuAC SmaCSM2_RS11235 2dc4f95b1744a017dd69b001626a6db4 509 Pfam PF02321 Outer membrane efflux protein 299 477 3.6E-10 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS11235 2dc4f95b1744a017dd69b001626a6db4 509 Pfam PF02321 Outer membrane efflux protein 71 265 9.7E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS11235 2dc4f95b1744a017dd69b001626a6db4 509 SUPERFAMILY SSF56954 62 479 5.75E-65 T 28-03-2018 SmaCSM2_RS11235 2dc4f95b1744a017dd69b001626a6db4 509 SUPERFAMILY SSF56954 7 32 5.75E-65 T 28-03-2018 SmaCSM2_RS11235 2dc4f95b1744a017dd69b001626a6db4 509 Gene3D G3DSA:1.20.1600.10 22 482 4.4E-57 T 28-03-2018 SmaCSM2_RS02770 06aecfa37a668bd2e4064b7ab4ea9748 351 SUPERFAMILY SSF51735 3 342 8.06E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02770 06aecfa37a668bd2e4064b7ab4ea9748 351 Gene3D G3DSA:3.90.25.10 193 348 1.9E-48 T 28-03-2018 SmaCSM2_RS02770 06aecfa37a668bd2e4064b7ab4ea9748 351 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 335 2.4E-153 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SmaCSM2_RS02770 06aecfa37a668bd2e4064b7ab4ea9748 351 Gene3D G3DSA:3.40.50.720 2 192 5.5E-40 T 28-03-2018 SmaCSM2_RS02770 06aecfa37a668bd2e4064b7ab4ea9748 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 321 1.7E-100 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS01350 18bf561d4db990dcebb47e7f3fccf1da 284 Pfam PF05036 Sporulation related domain 172 240 3.2E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01350 18bf561d4db990dcebb47e7f3fccf1da 284 Gene3D G3DSA:3.30.70.1070 142 207 2.2E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01350 18bf561d4db990dcebb47e7f3fccf1da 284 Gene3D G3DSA:3.30.70.1070 50 141 0.54 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01350 18bf561d4db990dcebb47e7f3fccf1da 284 Gene3D G3DSA:3.30.70.1070 208 284 0.0034 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01350 18bf561d4db990dcebb47e7f3fccf1da 284 SUPERFAMILY SSF110997 171 243 5.1E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Pfam PF00593 TonB dependent receptor 341 997 4.9E-12 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Gene3D G3DSA:2.40.170.20 269 998 7.5E-57 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Pfam PF07715 TonB-dependent Receptor Plug Domain 135 236 3.2E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 SUPERFAMILY SSF56935 922 998 2.96E-65 T 28-03-2018 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 SUPERFAMILY SSF56935 668 712 2.96E-65 T 28-03-2018 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 SUPERFAMILY SSF56935 114 615 2.96E-65 T 28-03-2018 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 SUPERFAMILY SSF56935 769 884 2.96E-65 T 28-03-2018 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Gene3D G3DSA:2.60.40.1120 26 114 1.4E-12 T 28-03-2018 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Gene3D G3DSA:2.170.130.10 133 251 2.6E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 SUPERFAMILY SSF49452 27 111 2.35E-11 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SmaCSM2_RS01940 3bf133e742f1a93b14d15a688b0bfa4a 999 Pfam PF13620 Carboxypeptidase regulatory-like domain 32 112 3.4E-15 T 28-03-2018 SmaCSM2_RS17255 c7533347afb40c48d10d8950a960df0e 149 Gene3D G3DSA:1.20.5.100 26 52 3.0E-5 T 28-03-2018 SmaCSM2_RS17255 c7533347afb40c48d10d8950a960df0e 149 Pfam PF14316 Domain of unknown function (DUF4381) 6 133 1.3E-27 T 28-03-2018 IPR025489 Protein of unknown function (DUF4381 SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 Gene3D G3DSA:1.10.238.10 101 125 6.9E-9 T 28-03-2018 SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 Gene3D G3DSA:1.10.238.10 126 156 6.1E-5 T 28-03-2018 SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 SUPERFAMILY SSF47473 89 140 1.78E-9 T 28-03-2018 IPR011992 EF-hand domain pair SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 ProSitePatterns PS00018 EF-hand calcium-binding domain. 94 106 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 Gene3D G3DSA:1.10.238.10 53 100 0.0043 T 28-03-2018 SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 Pfam PF13202 EF hand 117 132 4.0E-4 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS05615 3c74c295c5e57dd6d449bb284cab7913 158 Pfam PF13202 EF hand 90 109 0.0029 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SmaCSM2_RS21315 3bca4c6e623763e6e67a73d860a497fb 590 Pfam PF05960 Bacterial protein of unknown function (DUF885) 70 580 1.2E-156 T 28-03-2018 IPR010281 Protein of unknown function DUF885 SmaCSM2_RS12890 b20d230ee8481b1b491d6dc2c5ab3eca 98 Gene3D G3DSA:3.30.10.10 43 96 2.4E-4 T 28-03-2018 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 Pfam PF03572 Peptidase family S41 208 372 1.5E-55 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 Gene3D G3DSA:3.90.226.10 183 441 3.4E-67 T 28-03-2018 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 SMART SM00228 110 180 6.5E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 Pfam PF13180 PDZ domain 111 189 1.1E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 Gene3D G3DSA:2.30.42.10 110 182 3.2E-16 T 28-03-2018 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 Gene3D G3DSA:3.30.750.44 47 109 1.9E-15 T 28-03-2018 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 SUPERFAMILY SSF50156 111 190 7.97E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 SMART SM00245 182 374 1.4E-73 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 SUPERFAMILY SSF52096 44 130 5.14E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 SUPERFAMILY SSF52096 201 377 5.14E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS01745 9bd15aef953604e96e8915dd3af6e8a5 486 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 64 379 3.2E-95 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 SmaCSM2_RS05835 d9c383b081b3a5faeb7885c104825388 402 Gene3D G3DSA:3.60.10.10 21 401 1.5E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS05835 d9c383b081b3a5faeb7885c104825388 402 SUPERFAMILY SSF56219 139 400 2.16E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS05835 d9c383b081b3a5faeb7885c104825388 402 SUPERFAMILY SSF56219 35 106 2.16E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS05835 d9c383b081b3a5faeb7885c104825388 402 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 38 393 6.8E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS18520 3b3a121f36546f15ec78d2218880e4c0 200 PIRSF PIRSF036893 1 194 4.0E-36 T 28-03-2018 IPR022271 Lipocalin, ApoD type SmaCSM2_RS18520 3b3a121f36546f15ec78d2218880e4c0 200 ProSitePatterns PS00213 Lipocalin signature. 44 55 - T 28-03-2018 IPR022272 Lipocalin family conserved site SmaCSM2_RS18520 3b3a121f36546f15ec78d2218880e4c0 200 Gene3D G3DSA:2.40.128.20 2 186 2.5E-24 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS18520 3b3a121f36546f15ec78d2218880e4c0 200 SUPERFAMILY SSF50814 12 184 1.56E-29 T 28-03-2018 IPR012674 Calycin SmaCSM2_RS18520 3b3a121f36546f15ec78d2218880e4c0 200 Pfam PF08212 Lipocalin-like domain 43 184 6.6E-38 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain SmaCSM2_RS13775 0884eb91d97852bb5b5f7fe87070082f 321 Gene3D G3DSA:1.20.120.450 28 182 7.0E-4 T 28-03-2018 SmaCSM2_RS13775 0884eb91d97852bb5b5f7fe87070082f 321 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 157 279 5.4E-7 T 28-03-2018 IPR018728 Domain of unknown function DUF2268 SmaCSM2_RS05030 09de3c69b9020a2e5c1373e39896b18d 188 Pfam PF02622 Uncharacterized ACR, COG1678 17 175 1.8E-48 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 SmaCSM2_RS05030 09de3c69b9020a2e5c1373e39896b18d 188 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 6 188 36.489 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 SmaCSM2_RS05030 09de3c69b9020a2e5c1373e39896b18d 188 Gene3D G3DSA:3.30.70.1300 47 119 1.6E-27 T 28-03-2018 SmaCSM2_RS05030 09de3c69b9020a2e5c1373e39896b18d 188 Gene3D G3DSA:3.40.1740.10 120 179 3.9E-11 T 28-03-2018 SmaCSM2_RS05030 09de3c69b9020a2e5c1373e39896b18d 188 SUPERFAMILY SSF143456 6 187 1.44E-62 T 28-03-2018 SmaCSM2_RS03230 2b1bb39b5270e625da92e5c635936911 87 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 4 85 1.2E-23 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SmaCSM2_RS03230 2b1bb39b5270e625da92e5c635936911 87 Hamap MF_00910 Cell division protein FtsL [ftsL]. 2 85 16.698 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SmaCSM2_RS03230 2b1bb39b5270e625da92e5c635936911 87 Pfam PF04999 Cell division protein FtsL 5 87 3.4E-24 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SmaCSM2_RS03610 4f7013d6fa1fdb57f5c50b7cd080b283 186 SUPERFAMILY SSF53927 6 180 5.14E-31 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS03610 4f7013d6fa1fdb57f5c50b7cd080b283 186 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 32 130 3.6E-11 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SmaCSM2_RS03610 4f7013d6fa1fdb57f5c50b7cd080b283 186 Gene3D G3DSA:3.40.140.10 11 182 2.2E-23 T 28-03-2018 SmaCSM2_RS00890 a5ca650bb396b01a21995c9258c039ab 330 Gene3D G3DSA:3.40.50.720 1 328 8.7E-60 T 28-03-2018 SmaCSM2_RS00890 a5ca650bb396b01a21995c9258c039ab 330 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 4 253 1.8E-52 T 28-03-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 SmaCSM2_RS00890 a5ca650bb396b01a21995c9258c039ab 330 SUPERFAMILY SSF51735 1 325 4.35E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS04675 cc83c51dfdf4580f1d6cd06d1d3a446b 110 Gene3D G3DSA:1.10.260.40 2 86 1.1E-18 T 28-03-2018 SmaCSM2_RS04675 cc83c51dfdf4580f1d6cd06d1d3a446b 110 SUPERFAMILY SSF47413 7 79 2.22E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS04675 cc83c51dfdf4580f1d6cd06d1d3a446b 110 SMART SM00530 14 75 1.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS04675 cc83c51dfdf4580f1d6cd06d1d3a446b 110 Pfam PF13560 Helix-turn-helix domain 10 72 8.4E-12 T 28-03-2018 SmaCSM2_RS12105 9dd174bb4fcd62c068151ef82cd2501b 538 Gene3D G3DSA:3.10.20.310 46 114 7.3E-12 T 28-03-2018 SmaCSM2_RS12105 9dd174bb4fcd62c068151ef82cd2501b 538 Gene3D G3DSA:2.40.160.50 146 538 2.3E-53 T 28-03-2018 SmaCSM2_RS12105 9dd174bb4fcd62c068151ef82cd2501b 538 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 177 500 8.5E-26 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal SmaCSM2_RS12105 9dd174bb4fcd62c068151ef82cd2501b 538 Pfam PF08479 POTRA domain, ShlB-type 41 112 6.8E-14 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type SmaCSM2_RS02825 13e977c10cc6dc82c9f7fd1106190fa8 213 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 34 197 4.8E-40 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component SmaCSM2_RS02825 13e977c10cc6dc82c9f7fd1106190fa8 213 SUPERFAMILY SSF159594 34 203 1.46E-46 T 28-03-2018 SmaCSM2_RS02825 13e977c10cc6dc82c9f7fd1106190fa8 213 Gene3D G3DSA:3.40.50.10610 18 213 4.3E-46 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component SmaCSM2_RS16490 ea927b3398b282bf2fedb72334732da7 120 SMART SM00448 2 115 3.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16490 ea927b3398b282bf2fedb72334732da7 120 Pfam PF00072 Response regulator receiver domain 4 116 2.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS16490 ea927b3398b282bf2fedb72334732da7 120 SUPERFAMILY SSF52172 1 119 2.28E-35 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS16490 ea927b3398b282bf2fedb72334732da7 120 Gene3D G3DSA:3.40.50.2300 1 120 1.4E-34 T 28-03-2018 SmaCSM2_RS02010 5b00488ff10dddcc1e55034ca889dc7e 283 PIRSF PIRSF028477 3 283 1.4E-103 T 28-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 SmaCSM2_RS02010 5b00488ff10dddcc1e55034ca889dc7e 283 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 58 258 1.5E-73 T 28-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 SmaCSM2_RS10430 00d965d628c92311c18628af7651e3de 374 Gene3D G3DSA:3.40.630.30 185 367 8.9E-34 T 28-03-2018 SmaCSM2_RS10430 00d965d628c92311c18628af7651e3de 374 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 9 371 2.9E-140 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition SmaCSM2_RS10430 00d965d628c92311c18628af7651e3de 374 Gene3D G3DSA:3.40.630.30 5 184 3.1E-4 T 28-03-2018 SmaCSM2_RS10430 00d965d628c92311c18628af7651e3de 374 SUPERFAMILY SSF55729 183 352 1.88E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 71 2.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 Pfam PF03466 LysR substrate binding domain 96 305 1.9E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 Gene3D G3DSA:3.40.190.10 100 185 1.3E-15 T 28-03-2018 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 Gene3D G3DSA:3.40.190.10 186 277 2.0E-28 T 28-03-2018 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 Gene3D G3DSA:1.10.10.10 10 92 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 SUPERFAMILY SSF53850 98 306 4.34E-42 T 28-03-2018 SmaCSM2_RS05550 e47a922ab0cdcd31f0ef3821eaa488dd 324 SUPERFAMILY SSF46785 13 120 1.99E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02050 2a3dc020abed084862be29b9236e124b 186 Gene3D G3DSA:1.10.10.10 16 127 3.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02050 2a3dc020abed084862be29b9236e124b 186 SUPERFAMILY SSF46785 18 111 2.86E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS02050 2a3dc020abed084862be29b9236e124b 186 Pfam PF03551 Transcriptional regulator PadR-like family 35 103 4.1E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SmaCSM2_RS03490 eef7c5ffd62cc30fb31dae5f30f0aaea 233 Gene3D G3DSA:3.40.50.1110 26 231 4.7E-24 T 28-03-2018 SmaCSM2_RS03490 eef7c5ffd62cc30fb31dae5f30f0aaea 233 SUPERFAMILY SSF52266 40 230 3.66E-40 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS03490 eef7c5ffd62cc30fb31dae5f30f0aaea 233 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 72 221 7.7E-11 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 Gene3D G3DSA:3.40.50.1000 79 221 3.4E-27 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 188 3.7E-30 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 215 6.4E-71 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 73 182 3.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 SUPERFAMILY SSF56784 8 212 5.2E-52 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS14680 66baf0eb1510a4e21844b0f40994c4b3 231 Gene3D G3DSA:1.10.150.240 22 78 4.6E-12 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 SUPERFAMILY SSF55347 127 320 3.92E-33 T 28-03-2018 SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 Gene3D G3DSA:3.40.50.720 1 134 9.2E-43 T 28-03-2018 SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 Gene3D G3DSA:3.30.360.10 135 360 5.7E-41 T 28-03-2018 SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 206 1.5E-6 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 SUPERFAMILY SSF51735 3 154 1.59E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS05505 ddf71c2aff8ebfbe5a5cfb0d46a7675e 374 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 1.9E-30 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 Pfam PF03466 LysR substrate binding domain 88 293 8.2E-45 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 SUPERFAMILY SSF53850 89 296 4.16E-43 T 28-03-2018 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 Gene3D G3DSA:3.40.190.10 92 178 2.8E-18 T 28-03-2018 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 SUPERFAMILY SSF46785 4 112 2.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 Gene3D G3DSA:1.10.10.10 3 83 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 Gene3D G3DSA:3.40.190.10 179 265 2.4E-25 T 28-03-2018 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS04360 cf4b5637ce40ed98caf72e088131a0c8 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.9E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 Pfam PF00578 AhpC/TSA family 5 132 8.7E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 Gene3D G3DSA:3.40.30.10 4 153 1.4E-31 T 28-03-2018 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 SUPERFAMILY SSF52833 1 187 2.62E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 6.2E-6 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 PIRSF PIRSF000239 1 187 1.0E-45 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 Gene3D G3DSA:3.30.1020.10 154 183 1.5E-9 T 28-03-2018 SmaCSM2_RS03660 225b6f21b80eb3be41d0734cbb6ced14 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 6.2E-94 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 PIRSF PIRSF004555 1 106 1.7E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 102 1.1E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 Gene3D G3DSA:3.30.1310.10 1 106 6.7E-42 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 SUPERFAMILY SSF82607 9 100 2.75E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 95 22.84 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS04730 32b6bee24247028f065c64db1e849740 106 Pfam PF02575 YbaB/EbfC DNA-binding family 9 96 3.6E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SmaCSM2_RS10615 fe5de847e80cae03e7e9d4f12f9c1ceb 161 PIRSF PIRSF005859 2 158 2.2E-44 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 SmaCSM2_RS10615 fe5de847e80cae03e7e9d4f12f9c1ceb 161 Pfam PF03073 TspO/MBR family 15 154 3.0E-39 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 Gene3D G3DSA:2.40.10.10 255 709 9.2E-17 T 28-03-2018 SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 SUPERFAMILY SSF50494 644 681 1.31E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 SUPERFAMILY SSF50494 212 298 1.31E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 SUPERFAMILY SSF50494 28 87 1.31E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 Pfam PF10459 Peptidase S46 22 717 8.4E-259 T 28-03-2018 IPR019500 Peptidase S46 GO:0008239|GO:0070009 SmaCSM2_RS04250 f5876abef9f0b1a35428e469ed953eb2 720 Gene3D G3DSA:2.40.10.10 50 153 5.8E-5 T 28-03-2018 SmaCSM2_RS17035 ae11fd9444917a3901637fb194008528 244 Pfam PF02390 Putative methyltransferase 72 239 2.5E-47 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SmaCSM2_RS17035 ae11fd9444917a3901637fb194008528 244 SUPERFAMILY SSF53335 23 241 6.0E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS17035 ae11fd9444917a3901637fb194008528 244 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 58 243 4.4E-44 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SmaCSM2_RS17035 ae11fd9444917a3901637fb194008528 244 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 30 244 28.607 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SmaCSM2_RS17035 ae11fd9444917a3901637fb194008528 244 Gene3D G3DSA:3.40.50.150 36 244 6.4E-30 T 28-03-2018 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 Gene3D G3DSA:3.40.50.620 1 181 4.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 PIRSF PIRSF000089 1 312 1.5E-103 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 256 282 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 SUPERFAMILY SSF52467 190 312 5.06E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 Pfam PF01012 Electron transfer flavoprotein domain 5 173 2.6E-31 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 SUPERFAMILY SSF52402 4 180 1.05E-43 T 28-03-2018 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 Gene3D G3DSA:3.40.50.1220 188 312 1.3E-56 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 193 275 1.2E-35 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 SmaCSM2_RS02760 9dcc3757c99ddb16cebcf0c7c0686e9a 312 SMART SM00893 4 185 1.5E-36 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SmaCSM2_RS07555 544ef4de7fc5610565ee90a02fb25a83 148 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 35 144 3.5E-42 T 28-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 SmaCSM2_RS07555 544ef4de7fc5610565ee90a02fb25a83 148 Pfam PF07511 Protein of unknown function (DUF1525) 35 145 7.8E-42 T 28-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 SmaCSM2_RS05180 316d6201b19ebfdb64b91a71c3de48e6 379 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 37 272 2.5E-63 T 28-03-2018 IPR018642 Protein of unknown function DUF2066 SmaCSM2_RS05180 316d6201b19ebfdb64b91a71c3de48e6 379 Gene3D G3DSA:3.90.1150.10 236 312 0.063 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS14575 daaef0cb00e2ccc24d994658e729f6a2 418 SUPERFAMILY SSF53448 42 327 4.69E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS14575 daaef0cb00e2ccc24d994658e729f6a2 418 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 10 416 2.7E-188 T 28-03-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 SmaCSM2_RS14575 daaef0cb00e2ccc24d994658e729f6a2 418 Gene3D G3DSA:3.90.550.10 25 311 2.8E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS14575 daaef0cb00e2ccc24d994658e729f6a2 418 Pfam PF13641 Glycosyltransferase like family 2 55 276 2.5E-33 T 28-03-2018 SmaCSM2_RS04750 a90a08339327e35a936f779c7c69b26f 649 SUPERFAMILY SSF54001 276 594 3.64E-60 T 28-03-2018 SmaCSM2_RS04750 a90a08339327e35a936f779c7c69b26f 649 Pfam PF11992 Domain of unknown function (DUF3488) 13 327 4.0E-82 T 28-03-2018 IPR021878 Protein of unknown function DUF3488 SmaCSM2_RS04750 a90a08339327e35a936f779c7c69b26f 649 Gene3D G3DSA:3.90.260.10 357 490 1.2E-21 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS04750 a90a08339327e35a936f779c7c69b26f 649 SMART SM00460 402 473 3.2E-20 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS04750 a90a08339327e35a936f779c7c69b26f 649 Pfam PF01841 Transglutaminase-like superfamily 356 471 3.7E-27 T 28-03-2018 IPR002931 Transglutaminase-like SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 83 94 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 Gene3D G3DSA:3.40.1010.10 3 113 2.4E-38 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 203 7.5E-29 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 270 2.2E-82 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 SUPERFAMILY SSF53790 4 224 3.27E-78 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 PIRSF PIRSF005917 1 272 1.3E-99 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 5 226 37.38 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SmaCSM2_RS03200 b7e519245864e5e559976335b4c1902c 272 Gene3D G3DSA:3.30.950.10 114 229 1.9E-40 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SmaCSM2_RS17860 db239a16ab3336f936d0a972db8748ab 247 Pfam PF04450 Peptidase of plants and bacteria 85 228 3.1E-16 T 28-03-2018 IPR007541 Uncharacterised protein family, basic secretory protein SmaCSM2_RS17635 c2bef0f02481123d3fb9b269f959450d 239 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 160 235 7.3E-19 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS17635 c2bef0f02481123d3fb9b269f959450d 239 Gene3D G3DSA:3.30.1150.10 59 239 2.8E-20 T 28-03-2018 SmaCSM2_RS17635 c2bef0f02481123d3fb9b269f959450d 239 SUPERFAMILY SSF74653 99 107 7.85E-18 T 28-03-2018 SmaCSM2_RS17635 c2bef0f02481123d3fb9b269f959450d 239 SUPERFAMILY SSF74653 134 235 7.85E-18 T 28-03-2018 SmaCSM2_RS17635 c2bef0f02481123d3fb9b269f959450d 239 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 158 234 1.7E-17 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 Gene3D G3DSA:1.20.1260.10 1 149 3.2E-37 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PIRSF PIRSF002560 1 157 1.2E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 9.3E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 Pfam PF00210 Ferritin-like domain 9 144 1.8E-35 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 SUPERFAMILY SSF47240 1 156 4.07E-43 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 44 64 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 128 149 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 106 126 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 23 43 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 85 105 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS06735 8c0fcf2f263b0a7b75eaf9c03aad16ff 162 PRINTS PR00601 Bacterioferritin signature 3 22 1.1E-35 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 Gene3D G3DSA:3.65.10.10 224 435 6.7E-52 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 ProSitePatterns PS00104 EPSP synthase signature 1. 92 106 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 SUPERFAMILY SSF55205 7 432 4.09E-128 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 PIRSF PIRSF000505 6 435 1.3E-119 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 433 31.992 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 ProSitePatterns PS00885 EPSP synthase signature 2. 344 362 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 423 1.0E-117 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 Gene3D G3DSA:3.65.10.10 24 223 4.2E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS13635 190126185c1ba0f4a2d9296425f178e6 435 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 425 3.8E-121 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SmaCSM2_RS06655 457300af271fa49eaccc262f3dc6c901 231 Gene3D G3DSA:2.60.40.10 18 112 2.3E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS06655 457300af271fa49eaccc262f3dc6c901 231 SUPERFAMILY SSF49354 16 125 7.85E-7 T 28-03-2018 IPR008962 PapD-like SmaCSM2_RS21090 60a5889dc7039eccac2da4e371bc2371 791 Gene3D G3DSA:1.20.1640.10 608 784 4.2E-21 T 28-03-2018 SmaCSM2_RS21090 60a5889dc7039eccac2da4e371bc2371 791 Gene3D G3DSA:1.20.1640.10 233 415 4.1E-19 T 28-03-2018 SmaCSM2_RS21090 60a5889dc7039eccac2da4e371bc2371 791 SUPERFAMILY SSF82866 247 415 1.57E-20 T 28-03-2018 SmaCSM2_RS21090 60a5889dc7039eccac2da4e371bc2371 791 SUPERFAMILY SSF82866 622 783 3.4E-20 T 28-03-2018 SmaCSM2_RS07955 cd079a1c8e97f9e313c8d11a31b547c5 255 SUPERFAMILY SSF52821 106 234 9.05E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS07955 cd079a1c8e97f9e313c8d11a31b547c5 255 Pfam PF00581 Rhodanese-like domain 119 213 8.2E-5 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS07955 cd079a1c8e97f9e313c8d11a31b547c5 255 Gene3D G3DSA:3.40.250.10 106 224 5.4E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS07955 cd079a1c8e97f9e313c8d11a31b547c5 255 SMART SM00450 118 219 2.9E-10 T 28-03-2018 IPR001763 Rhodanese-like domain SmaCSM2_RS04375 177129a05aefde7805b03ed1aedb9a2a 252 PIRSF PIRSF009160 1 252 2.7E-94 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 SmaCSM2_RS04375 177129a05aefde7805b03ed1aedb9a2a 252 Pfam PF12811 Bax inhibitor 1 like 23 251 3.4E-80 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Gene3D G3DSA:1.10.540.10 82 240 1.5E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 SUPERFAMILY SSF56645 124 360 2.09E-43 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Gene3D G3DSA:1.20.140.10 354 513 3.2E-23 T 28-03-2018 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Gene3D G3DSA:2.40.110.10 241 353 2.2E-13 T 28-03-2018 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 SUPERFAMILY SSF47203 365 511 8.54E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 365 510 2.3E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Pfam PF09317 Domain of unknown function (DUF1974) 519 802 1.2E-109 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 SmaCSM2_RS16380 a3f4a14a439bec1b160e95a43cab1659 825 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 142 237 1.3E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 Gene3D G3DSA:3.30.870.10 96 282 4.2E-31 T 28-03-2018 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 SUPERFAMILY SSF56024 95 301 3.14E-50 T 28-03-2018 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 Gene3D G3DSA:3.30.870.10 304 471 3.2E-25 T 28-03-2018 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 21 469 2.5E-100 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 SUPERFAMILY SSF56024 263 459 9.42E-47 T 28-03-2018 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 Pfam PF13091 PLD-like domain 314 432 1.3E-23 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 Pfam PF13091 PLD-like domain 130 271 1.7E-19 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 57 1.3E-4 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 SMART SM00155 214 241 4.2E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS21265 2050571da27afe6db0aedd43194b9449 472 SMART SM00155 385 412 0.033 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS05780 fbf07ed05f5653b0432b2d1673540eac 198 PIRSF PIRSF028520 1 165 3.4E-73 T 28-03-2018 IPR016890 Uncharacterised conserved protein UCP028520 SmaCSM2_RS05780 fbf07ed05f5653b0432b2d1673540eac 198 Pfam PF00583 Acetyltransferase (GNAT) family 27 141 3.2E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS05780 fbf07ed05f5653b0432b2d1673540eac 198 Gene3D G3DSA:3.40.630.30 1 165 1.8E-16 T 28-03-2018 SmaCSM2_RS05780 fbf07ed05f5653b0432b2d1673540eac 198 SUPERFAMILY SSF55729 2 150 5.59E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS08715 735fb8c0a99acf38a909974918a1f615 130 Gene3D G3DSA:3.30.1450.10 28 100 9.9E-10 T 28-03-2018 SmaCSM2_RS08715 735fb8c0a99acf38a909974918a1f615 130 Pfam PF04355 SmpA / OmlA family 28 98 1.9E-20 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 SmaCSM2_RS08715 735fb8c0a99acf38a909974918a1f615 130 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 1 110 30.214 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 Hamap MF_00165 Thymidylate kinase [tmk]. 10 215 29.359 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 SUPERFAMILY SSF52540 9 212 1.28E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 ProSitePatterns PS01331 Thymidylate kinase signature. 103 115 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 10 206 7.9E-50 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 Pfam PF02223 Thymidylate kinase 14 206 2.2E-46 T 28-03-2018 SmaCSM2_RS04825 de878a373bfecf2a5b8487fab35a2cd7 221 Gene3D G3DSA:3.40.50.300 6 216 1.6E-48 T 28-03-2018 SmaCSM2_RS15980 4bb6e233cacb0349307c0c70545f4e4e 287 Pfam PF02678 Pirin 16 120 1.2E-34 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SmaCSM2_RS15980 4bb6e233cacb0349307c0c70545f4e4e 287 PIRSF PIRSF006232 1 280 2.1E-91 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SmaCSM2_RS15980 4bb6e233cacb0349307c0c70545f4e4e 287 Gene3D G3DSA:2.60.120.10 1 244 4.9E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS15980 4bb6e233cacb0349307c0c70545f4e4e 287 Pfam PF05726 Pirin C-terminal cupin domain 174 272 8.5E-26 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SmaCSM2_RS15980 4bb6e233cacb0349307c0c70545f4e4e 287 SUPERFAMILY SSF51182 3 284 1.82E-80 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS10400 67990a4530e05b793cbed0a3c5b227a1 92 SUPERFAMILY SSF143011 1 92 1.31E-15 T 28-03-2018 IPR035095 Toxin RelE-like domain SmaCSM2_RS10400 67990a4530e05b793cbed0a3c5b227a1 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 92 2.3E-25 T 28-03-2018 IPR007711 Toxin HigB-1 SmaCSM2_RS10400 67990a4530e05b793cbed0a3c5b227a1 92 Gene3D G3DSA:3.30.2310.20 1 92 1.2E-24 T 28-03-2018 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 PRINTS PR00990 Ribokinase signature 7 28 3.1E-20 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 PRINTS PR00990 Ribokinase signature 103 116 3.1E-20 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 PRINTS PR00990 Ribokinase signature 172 187 3.1E-20 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 PRINTS PR00990 Ribokinase signature 225 236 3.1E-20 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 Hamap MF_01987 Ribokinase [rbsK]. 3 319 23.183 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 262 275 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 Pfam PF00294 pfkB family carbohydrate kinase 4 311 4.6E-50 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 SUPERFAMILY SSF53613 2 312 2.34E-61 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS03420 07530f518d7eedbc06fbd76b82e548c1 321 Gene3D G3DSA:3.40.1190.20 1 319 1.4E-61 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS10980 a21c12a33e7484352c421b5a9802fc85 302 SUPERFAMILY SSF103481 189 285 1.44E-8 T 28-03-2018 SmaCSM2_RS10980 a21c12a33e7484352c421b5a9802fc85 302 Pfam PF00892 EamA-like transporter family 3 135 1.4E-24 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS10980 a21c12a33e7484352c421b5a9802fc85 302 Pfam PF00892 EamA-like transporter family 150 280 1.1E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS10980 a21c12a33e7484352c421b5a9802fc85 302 SUPERFAMILY SSF103481 35 138 8.63E-13 T 28-03-2018 SmaCSM2_RS16705 a2298af71b512a8b0544d7b513c1243d 639 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 19 639 33.588 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup SmaCSM2_RS16705 a2298af71b512a8b0544d7b513c1243d 639 Pfam PF02705 K+ potassium transporter 28 560 7.9E-215 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 Gene3D G3DSA:2.40.50.100 52 116 5.9E-12 T 28-03-2018 SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 Gene3D G3DSA:2.40.50.100 214 265 0.029 T 28-03-2018 SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 SUPERFAMILY SSF111369 176 266 8.5E-8 T 28-03-2018 SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 52 296 7.3E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 SUPERFAMILY SSF111369 51 112 3.27E-6 T 28-03-2018 SmaCSM2_RS06180 854c0fd1b910cecd5adc54fdb72c7a0d 337 Gene3D G3DSA:1.10.287.470 121 213 3.0E-5 T 28-03-2018 SmaCSM2_RS00415 5e5404fe6c106d2bc9d12d52cc50abc2 129 Gene3D G3DSA:3.30.10.10 71 127 8.7E-5 T 28-03-2018 SmaCSM2_RS00415 5e5404fe6c106d2bc9d12d52cc50abc2 129 Pfam PF11720 Peptidase inhibitor I78 family 65 129 2.6E-19 T 28-03-2018 IPR021719 Proteinase inhibitor I78 SmaCSM2_RS01810 095148253edcb18022ea05e7c7745126 238 Pfam PF02104 SURF1 family 16 219 5.1E-24 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Gene3D G3DSA:2.160.10.10 171 341 1.3E-35 T 28-03-2018 SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 216 250 1.4E-4 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 84 356 54.252 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 SUPERFAMILY SSF51161 87 340 3.33E-69 T 28-03-2018 IPR011004 Trimeric LpxA-like SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Gene3D G3DSA:1.10.166.10 86 153 8.0E-23 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 259 293 1.5E-10 T 28-03-2018 IPR001451 Hexapeptide repeat SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 87 153 2.2E-21 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 SmaCSM2_RS06695 7093aae5fa5a5681cebab773b4859f23 359 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 90 356 2.7E-126 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 SmaCSM2_RS16435 d449959d6c03e7aa724c1149cf74aceb 109 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 106 2.3E-42 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 SmaCSM2_RS16435 d449959d6c03e7aa724c1149cf74aceb 109 SUPERFAMILY SSF103481 7 105 2.75E-7 T 28-03-2018 SmaCSM2_RS16435 d449959d6c03e7aa724c1149cf74aceb 109 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 105 26.355 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 SmaCSM2_RS19990 43b2203a7929de0dbf337b4876d7cdce 236 Gene3D G3DSA:2.60.120.10 120 231 0.12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS19990 43b2203a7929de0dbf337b4876d7cdce 236 Gene3D G3DSA:2.60.120.10 4 119 6.3E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS19990 43b2203a7929de0dbf337b4876d7cdce 236 SUPERFAMILY SSF51182 136 197 1.78E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS19990 43b2203a7929de0dbf337b4876d7cdce 236 Pfam PF12973 ChrR Cupin-like domain 20 108 1.2E-38 T 28-03-2018 IPR025979 ChrR-like cupin domain SmaCSM2_RS19990 43b2203a7929de0dbf337b4876d7cdce 236 SUPERFAMILY SSF51182 3 127 5.94E-36 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS14520 a35cc59a13ac40eefcd7e08c49bc0f20 114 Pfam PF06961 Protein of unknown function (DUF1294) 36 90 7.0E-25 T 28-03-2018 IPR010718 Protein of unknown function DUF1294 SmaCSM2_RS14520 a35cc59a13ac40eefcd7e08c49bc0f20 114 Gene3D G3DSA:1.20.1250.20 60 111 0.007 T 28-03-2018 SmaCSM2_RS14520 a35cc59a13ac40eefcd7e08c49bc0f20 114 PIRSF PIRSF002599 9 114 3.2E-21 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 Gene3D G3DSA:1.10.287.470 135 177 2.5E-8 T 28-03-2018 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 SUPERFAMILY SSF111369 56 132 1.2E-8 T 28-03-2018 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 Pfam PF13533 Biotin-lipoyl like 57 105 9.0E-15 T 28-03-2018 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 199 287 2.0E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 Gene3D G3DSA:2.40.50.100 56 134 1.3E-12 T 28-03-2018 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 SUPERFAMILY SSF111369 161 264 5.49E-10 T 28-03-2018 SmaCSM2_RS06760 6bf4c45e06eb165f59f12dee5d29c148 392 Gene3D G3DSA:2.40.50.100 205 380 1.4E-8 T 28-03-2018 SmaCSM2_RS11310 423ea0dc2d898f6a737b00a1a36b5afc 130 SMART SM00448 10 116 1.1E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11310 423ea0dc2d898f6a737b00a1a36b5afc 130 SUPERFAMILY SSF52172 9 121 1.99E-19 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11310 423ea0dc2d898f6a737b00a1a36b5afc 130 Gene3D G3DSA:3.40.50.2300 1 128 1.4E-16 T 28-03-2018 SmaCSM2_RS11310 423ea0dc2d898f6a737b00a1a36b5afc 130 Pfam PF00072 Response regulator receiver domain 13 116 5.9E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 28 3.2E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 Gene3D G3DSA:3.30.1300.30 46 117 1.0E-8 T 28-03-2018 SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 Gene3D G3DSA:3.30.700.10 8 45 9.1E-4 T 28-03-2018 SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 SUPERFAMILY SSF54523 8 65 1.18E-6 T 28-03-2018 SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 Pfam PF02501 Type II secretion system (T2SS), protein I 41 113 1.9E-8 T 28-03-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 1.7E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS12125 34dbf4416e78507408ca733e05b23cea 120 TIGRFAM TIGR01707 gspI: type II secretion system protein I 7 101 1.4E-19 T 28-03-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 109 125 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 331 349 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 291 310 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 127 144 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 22 40 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 40 54 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 85 104 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 156 176 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PRINTS PR00681 Ribosomal protein S1 signature 213 234 2.0E-86 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 362 435 1.3E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 104 172 1.8E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 18 87 2.7E-4 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 277 348 1.3E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 189 261 1.5E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Pfam PF00575 S1 RNA binding domain 451 521 2.6E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 521 7.3E-210 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 1 113 1.25E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 256 359 2.76E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 452 547 1.2E-18 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 191 277 1.04E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 97 178 2.7E-8 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 183 267 1.5E-26 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 358 441 4.0E-21 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 344 441 4.4E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 104 186 2.24E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 2 93 2.1E-9 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 PIRSF PIRSF002111 1 535 1.9E-211 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 Gene3D G3DSA:2.40.50.140 276 349 1.7E-27 T 28-03-2018 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 20 88 6.7E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 191 261 1.3E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 104 172 7.1E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 450 521 8.6E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 276 348 1.2E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SMART SM00316 363 435 5.4E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 SmaCSM2_RS08990 f2eb6ebd07cb653df7875dc2cea22ecc 561 SUPERFAMILY SSF50249 434 537 6.79E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SmaCSM2_RS12550 fd9449937c63eb91bbf325d6901c653d 111 Pfam PF14559 Tetratricopeptide repeat 28 76 9.1E-6 T 28-03-2018 SmaCSM2_RS12550 fd9449937c63eb91bbf325d6901c653d 111 SUPERFAMILY SSF48452 7 102 5.42E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12550 fd9449937c63eb91bbf325d6901c653d 111 Gene3D G3DSA:1.25.40.10 1 110 1.7E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12550 fd9449937c63eb91bbf325d6901c653d 111 SMART SM00028 17 50 52.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS12550 fd9449937c63eb91bbf325d6901c653d 111 SMART SM00028 51 84 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 Gene3D G3DSA:3.20.20.140 2 257 7.2E-80 T 28-03-2018 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 126 136 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 PIRSF PIRSF005902 2 257 9.9E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 Pfam PF01026 TatD related DNase 5 252 3.7E-66 T 28-03-2018 IPR001130 TatD family GO:0016788 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SmaCSM2_RS14205 c52c779f2a217e5f9aff18af2a2a0cf4 257 SUPERFAMILY SSF51556 4 254 3.13E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 147 751 5.3E-91 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 Pfam PF03772 Competence protein 231 502 6.8E-60 T 28-03-2018 IPR004477 ComEC/Rec2-related protein SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 253 433 4.3E-21 T 28-03-2018 IPR004477 ComEC/Rec2-related protein SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 SMART SM00849 539 722 3.5E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 SUPERFAMILY SSF56281 527 767 8.67E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 Pfam PF13567 Domain of unknown function (DUF4131) 16 193 8.8E-18 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 SmaCSM2_RS07300 37d16b0a1e38b9fec1049979eeace9e0 799 Gene3D G3DSA:3.60.15.10 523 755 2.7E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase SmaCSM2_RS06680 7b331f54b6cf5a261148580a7774a819 176 SMART SM00972 113 173 4.4E-18 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS06680 7b331f54b6cf5a261148580a7774a819 176 Pfam PF05229 Spore Coat Protein U domain 27 173 1.3E-31 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS19810 f0623601688c9b4d1da1ef4e4ec2b019 201 SUPERFAMILY SSF52833 57 172 3.55E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS19810 f0623601688c9b4d1da1ef4e4ec2b019 201 Pfam PF13899 Thioredoxin-like 78 164 3.5E-16 T 28-03-2018 SmaCSM2_RS19810 f0623601688c9b4d1da1ef4e4ec2b019 201 Gene3D G3DSA:3.40.30.10 79 199 2.2E-7 T 28-03-2018 SmaCSM2_RS13335 a9dc8a230f059c026687f2a7a53202bb 145 Pfam PF13673 Acetyltransferase (GNAT) domain 36 126 2.9E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS13335 a9dc8a230f059c026687f2a7a53202bb 145 Gene3D G3DSA:3.40.630.30 1 145 8.5E-28 T 28-03-2018 SmaCSM2_RS13335 a9dc8a230f059c026687f2a7a53202bb 145 SUPERFAMILY SSF55729 2 142 4.01E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 Pfam PF07687 Peptidase dimerisation domain 160 266 8.8E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 Gene3D G3DSA:3.40.630.10 1 362 5.9E-34 T 28-03-2018 SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 SUPERFAMILY SSF53187 2 162 1.7E-35 T 28-03-2018 SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 SUPERFAMILY SSF53187 284 359 1.7E-35 T 28-03-2018 SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 Pfam PF01546 Peptidase family M20/M25/M40 64 359 1.2E-18 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SmaCSM2_RS14620 2a2720655999a859f37a54dc0af6f207 362 SUPERFAMILY SSF55031 162 266 1.73E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 50 253 2.1E-45 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 Pfam PF10503 Esterase PHB depolymerase 48 253 2.8E-38 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 Gene3D G3DSA:3.40.50.1820 43 311 3.2E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 SUPERFAMILY SSF53474 136 253 1.72E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 SUPERFAMILY SSF53474 292 332 1.72E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11415 15e50a0c7b8ea136b3f26a28a9f7bb9b 334 SUPERFAMILY SSF53474 20 137 5.25E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 SUPERFAMILY SSF52768 1 308 5.28E-98 T 28-03-2018 SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 PRINTS PR01270 Histone deacetylase superfamily signature 118 141 1.0E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 PRINTS PR01270 Histone deacetylase superfamily signature 232 242 1.0E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 PRINTS PR01270 Histone deacetylase superfamily signature 152 167 1.0E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 Gene3D G3DSA:3.40.800.20 1 311 1.7E-100 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SmaCSM2_RS03575 45f201e696fe4ffe290527698f4c9192 312 Pfam PF00850 Histone deacetylase domain 18 302 3.8E-76 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SmaCSM2_RS14425 0827535f0a0d174dbe4d33ed982675e1 301 Gene3D G3DSA:1.10.10.580 208 276 6.8E-14 T 28-03-2018 SmaCSM2_RS14425 0827535f0a0d174dbe4d33ed982675e1 301 Hamap MF_01805 Segregation and condensation protein A [scpA]. 47 277 21.769 T 28-03-2018 IPR003768 Segregation and condensation protein A SmaCSM2_RS14425 0827535f0a0d174dbe4d33ed982675e1 301 Pfam PF02616 Segregation and condensation protein ScpA 64 274 8.7E-29 T 28-03-2018 IPR003768 Segregation and condensation protein A SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 24.297 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 PRINTS PR01249 Ribosomal protein L31 signature 60 78 6.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 PRINTS PR01249 Ribosomal protein L31 signature 45 60 6.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 9.2E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 SUPERFAMILY SSF143800 1 79 1.02E-22 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS17350 45ffdf3fb90b7b5c93cb1d217f200987 80 Pfam PF01197 Ribosomal protein L31 1 79 9.8E-30 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS18310 ac673da429cbf2d11d7ffa837f5ba80e 204 Pfam PF10001 Uncharacterized protein conserved in bacteria (DUF2242) 54 171 7.0E-52 T 28-03-2018 IPR018718 Protein of unknown function DUF2242 SmaCSM2_RS18310 ac673da429cbf2d11d7ffa837f5ba80e 204 Gene3D G3DSA:3.40.190.10 1 172 7.2E-4 T 28-03-2018 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Gene3D G3DSA:2.40.30.10 269 382 1.2E-18 T 28-03-2018 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Pfam PF16658 Class II release factor RF3, C-terminal domain 385 512 1.3E-46 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Gene3D G3DSA:3.40.50.300 4 268 1.3E-35 T 28-03-2018 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 2.1E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 SUPERFAMILY SSF54980 391 466 1.22E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 525 52.798 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Gene3D G3DSA:3.30.70.870 392 467 2.2E-10 T 28-03-2018 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 1 526 1.0E-251 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 PRINTS PR00315 GTP-binding elongation factor signature 63 71 2.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 SUPERFAMILY SSF50447 259 391 1.44E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 SUPERFAMILY SSF52540 8 276 3.15E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16325 bee29b396cfe1d16aa6394b344452a4e 534 Pfam PF00009 Elongation factor Tu GTP binding domain 11 276 3.0E-48 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SmaCSM2_RS01115 cbe710076c37e44932b058aed9357897 133 SUPERFAMILY SSF54637 6 130 2.14E-41 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS01115 cbe710076c37e44932b058aed9357897 133 Gene3D G3DSA:3.10.129.10 1 132 8.2E-40 T 28-03-2018 SmaCSM2_RS01115 cbe710076c37e44932b058aed9357897 133 Pfam PF03061 Thioesterase superfamily 28 100 6.0E-19 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SmaCSM2_RS11915 a712c2897c7e20d8717ac2a67a3232fb 125 Gene3D G3DSA:2.60.40.1220 26 125 1.6E-22 T 28-03-2018 SmaCSM2_RS11915 a712c2897c7e20d8717ac2a67a3232fb 125 Pfam PF04234 CopC domain 27 124 3.8E-22 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 SmaCSM2_RS11915 a712c2897c7e20d8717ac2a67a3232fb 125 SUPERFAMILY SSF81296 26 125 7.7E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set SmaCSM2_RS04535 98b03cb74aecfc734106ddfc979f7367 105 SUPERFAMILY SSF103481 4 104 4.97E-22 T 28-03-2018 SmaCSM2_RS04535 98b03cb74aecfc734106ddfc979f7367 105 Pfam PF00893 Small Multidrug Resistance protein 1 92 1.1E-30 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SmaCSM2_RS18085 b9fd5ca5aa1d4438526db08707b5b89c 454 PIRSF PIRSF017901 2 454 5.6E-188 T 28-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SmaCSM2_RS18085 b9fd5ca5aa1d4438526db08707b5b89c 454 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 54 357 3.5E-96 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SmaCSM2_RS18085 b9fd5ca5aa1d4438526db08707b5b89c 454 SUPERFAMILY SSF55931 308 452 1.08E-70 T 28-03-2018 SmaCSM2_RS18085 b9fd5ca5aa1d4438526db08707b5b89c 454 SUPERFAMILY SSF55931 26 269 1.08E-70 T 28-03-2018 SmaCSM2_RS18085 b9fd5ca5aa1d4438526db08707b5b89c 454 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 11 454 4.6E-217 T 28-03-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SmaCSM2_RS19845 64c9629fdcc07c8486418a896d29dea1 128 PIRSF PIRSF039020 1 122 1.9E-41 T 28-03-2018 IPR026275 Glyoxalase/dioxygenase/EhpR SmaCSM2_RS19845 64c9629fdcc07c8486418a896d29dea1 128 SUPERFAMILY SSF54593 10 123 3.16E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19845 64c9629fdcc07c8486418a896d29dea1 128 Gene3D G3DSA:3.10.180.10 7 128 2.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19845 64c9629fdcc07c8486418a896d29dea1 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 115 1.2E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS14465 ba83844af03db385551a1eb18ba7a883 382 Pfam PF00155 Aminotransferase class I and II 28 379 6.0E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS14465 ba83844af03db385551a1eb18ba7a883 382 Gene3D G3DSA:3.90.1150.10 265 382 7.9E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS14465 ba83844af03db385551a1eb18ba7a883 382 Gene3D G3DSA:3.90.1150.10 1 71 0.03 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS14465 ba83844af03db385551a1eb18ba7a883 382 SUPERFAMILY SSF53383 3 380 3.46E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS14465 ba83844af03db385551a1eb18ba7a883 382 Gene3D G3DSA:3.40.640.10 72 264 7.6E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS13410 e4a323bc3b8625408518c568404e1651 135 Pfam PF04956 TrbC/VIRB2 family 9 107 1.7E-15 T 28-03-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 SmaCSM2_RS10905 6a9123ae6c9068e19f4bfee25438f1a9 350 Gene3D G3DSA:1.20.5.50 152 271 1.7E-5 T 28-03-2018 SmaCSM2_RS10905 6a9123ae6c9068e19f4bfee25438f1a9 350 Gene3D G3DSA:1.20.5.50 61 151 0.02 T 28-03-2018 SmaCSM2_RS10905 6a9123ae6c9068e19f4bfee25438f1a9 350 Gene3D G3DSA:1.20.5.340 272 346 0.032 T 28-03-2018 SmaCSM2_RS10905 6a9123ae6c9068e19f4bfee25438f1a9 350 Pfam PF11740 Plasmid replication region DNA-binding N-term 8 118 4.5E-23 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 Pfam PF00083 Sugar (and other) transporter 30 433 1.7E-34 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 ProSitePatterns PS00216 Sugar transport proteins signature 1. 306 323 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 Gene3D G3DSA:1.20.1250.20 21 228 5.2E-23 T 28-03-2018 SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 Gene3D G3DSA:1.20.1250.20 229 439 4.5E-18 T 28-03-2018 SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SmaCSM2_RS01425 57c68f8644742143cc4bf181da23a965 444 SUPERFAMILY SSF103473 22 431 1.28E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 SUPERFAMILY SSF52540 355 514 4.61E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 Gene3D G3DSA:3.40.50.300 353 528 1.2E-31 T 28-03-2018 SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 Gene3D G3DSA:3.40.50.300 1 278 9.7E-43 T 28-03-2018 SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 Pfam PF00005 ABC transporter 355 481 4.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 Pfam PF00005 ABC transporter 24 171 1.8E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 SMART SM00382 30 213 3.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 SMART SM00382 361 525 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS02200 9cf6a0125d993dc55f9fba4a59d2d1d1 535 SUPERFAMILY SSF52540 17 222 9.02E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 Gene3D G3DSA:1.10.357.10 1 185 7.6E-24 T 28-03-2018 SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 SUPERFAMILY SSF46689 2 70 3.08E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS11860 387b8d9699c86acf977af0a3a43a61ec 185 SUPERFAMILY SSF48498 79 177 9.78E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 Pfam PF01235 Sodium:alanine symporter family 50 482 3.8E-153 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 470 2.6E-137 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 315 333 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 224 243 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 376 398 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 86 108 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 439 459 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS17090 51602d5dcdbd186063097256d4e4b84f 503 PRINTS PR00175 Sodium/alanine symporter signature 196 214 1.0E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SmaCSM2_RS05670 5558f2ed747e2d97e8aa883dd451a89a 455 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 7.3E-66 T 28-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal SmaCSM2_RS05670 5558f2ed747e2d97e8aa883dd451a89a 455 Pfam PF03600 Citrate transporter 277 451 2.9E-10 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SmaCSM2_RS21115 7203b915d332d0f5050415e2919681b3 256 Gene3D G3DSA:3.90.550.10 14 255 6.2E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS21115 7203b915d332d0f5050415e2919681b3 256 Pfam PF00535 Glycosyl transferase family 2 16 138 1.9E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS21115 7203b915d332d0f5050415e2919681b3 256 SUPERFAMILY SSF53448 16 243 8.13E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS17055 a8c74f44be8755b80d476ca8047a3459 238 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 231 2.0E-54 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS17055 a8c74f44be8755b80d476ca8047a3459 238 SUPERFAMILY SSF56529 24 230 6.8E-64 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS17055 a8c74f44be8755b80d476ca8047a3459 238 Gene3D G3DSA:3.90.850.10 15 233 9.3E-70 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 Pfam PF00023 Ankyrin repeat 70 100 8.2E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 Pfam PF12796 Ankyrin repeats (3 copies) 113 204 6.4E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 SMART SM00248 135 164 59.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 SMART SM00248 36 65 1500.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 SMART SM00248 69 98 0.003 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 SMART SM00248 168 202 3.3 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 Gene3D G3DSA:1.25.40.20 26 126 5.1E-23 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 Gene3D G3DSA:1.25.40.20 127 233 7.8E-26 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS12845 6175f0072738e9f047ce6fd0119d4722 233 SUPERFAMILY SSF48403 41 231 3.73E-43 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS21605 f1cef109dea66c3ab5969bd6a8ff8ea1 679 Pfam PF04632 Fusaric acid resistance protein family 9 666 1.4E-200 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 SmaCSM2_RS16850 97956f50d6c1985c44800a4c021d7cf5 252 SUPERFAMILY SSF56784 19 249 2.6E-39 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS16850 97956f50d6c1985c44800a4c021d7cf5 252 Gene3D G3DSA:3.40.50.1000 19 251 4.2E-22 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS16850 97956f50d6c1985c44800a4c021d7cf5 252 Pfam PF02358 Trehalose-phosphatase 21 237 5.6E-37 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SmaCSM2_RS16850 97956f50d6c1985c44800a4c021d7cf5 252 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 19 248 9.6E-37 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SmaCSM2_RS16850 97956f50d6c1985c44800a4c021d7cf5 252 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 20 209 2.7E-19 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 SMART SM00732 20 120 7.1E-31 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 20 158 22.782 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 Gene3D G3DSA:3.30.420.140 18 162 2.1E-39 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 Pfam PF03652 Holliday junction resolvase 21 155 1.0E-36 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 SUPERFAMILY SSF53098 20 157 8.19E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS05035 645f63329d5807bdde9b7ed5451cf708 164 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 23 154 4.5E-32 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 Pfam PF00027 Cyclic nucleotide-binding domain 35 121 2.3E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 Gene3D G3DSA:2.60.120.10 8 161 8.1E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 Pfam PF00325 Bacterial regulatory proteins, crp family 185 216 2.4E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 SUPERFAMILY SSF46785 158 226 9.87E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 Gene3D G3DSA:1.10.10.10 162 227 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 201 1.8E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 201 216 1.8E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 SUPERFAMILY SSF51206 26 154 9.95E-24 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 ProSitePatterns PS00042 Crp-type HTH domain signature. 187 210 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 SMART SM00100 17 141 7.5E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SmaCSM2_RS19675 39a0ae1a96e39f053f08a2611bab6ce1 229 SMART SM00419 179 227 6.4E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SmaCSM2_RS16600 ca3422a74bc34792a7e620e0edebc3b2 312 SUPERFAMILY SSF53474 39 303 8.95E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16600 ca3422a74bc34792a7e620e0edebc3b2 312 Pfam PF00756 Putative esterase 57 268 1.8E-20 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SmaCSM2_RS16600 ca3422a74bc34792a7e620e0edebc3b2 312 Gene3D G3DSA:3.40.50.1820 46 303 1.6E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS11885 403e70a392d2f92deefa34236fe155e1 417 Pfam PF02687 FtsX-like permease family 315 406 5.8E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS11885 403e70a392d2f92deefa34236fe155e1 417 Pfam PF12704 MacB-like periplasmic core domain 18 214 1.3E-10 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS18610 1149460a75a69a5916412c66b0dac606 193 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 74 166 2.6E-16 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SmaCSM2_RS18610 1149460a75a69a5916412c66b0dac606 193 Pfam PF13186 Iron-sulfur cluster-binding domain 74 138 7.8E-9 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SmaCSM2_RS18610 1149460a75a69a5916412c66b0dac606 193 SUPERFAMILY SSF102114 56 147 1.18E-14 T 28-03-2018 SmaCSM2_RS02295 5f667decd720e1330ebd2f7e31cd256b 550 Gene3D G3DSA:3.40.50.10070 233 411 1.4E-13 T 28-03-2018 SmaCSM2_RS02295 5f667decd720e1330ebd2f7e31cd256b 550 Pfam PF03783 Curli production assembly/transport component CsgG 235 405 6.6E-11 T 28-03-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 SUPERFAMILY SSF57840 1 40 8.37E-14 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 17 40 0.007 T 28-03-2018 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 17.137 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 Pfam PF00444 Ribosomal protein L36 1 40 3.9E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS08980 56408f70b69b167aa1e8157a355da676 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 40 8.9E-9 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS17025 f775d5ac2b0e391f5b5b32b68812cf31 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 1.0E-21 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis SmaCSM2_RS17025 f775d5ac2b0e391f5b5b32b68812cf31 66 SUPERFAMILY SSF54285 2 65 5.23E-18 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SmaCSM2_RS17025 f775d5ac2b0e391f5b5b32b68812cf31 66 Gene3D G3DSA:3.10.20.30 1 66 2.7E-23 T 28-03-2018 IPR012675 Beta-grasp domain SmaCSM2_RS17025 f775d5ac2b0e391f5b5b32b68812cf31 66 Pfam PF02597 ThiS family 3 66 6.0E-14 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SmaCSM2_RS01755 4aece64b8aa1d3af5fb0c1f0c826b7f5 475 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 20 475 1.8E-119 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) SmaCSM2_RS01755 4aece64b8aa1d3af5fb0c1f0c826b7f5 475 Gene3D G3DSA:2.40.160.60 28 475 1.1E-73 T 28-03-2018 SmaCSM2_RS01755 4aece64b8aa1d3af5fb0c1f0c826b7f5 475 SUPERFAMILY SSF56935 29 475 7.05E-87 T 28-03-2018 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 Gene3D G3DSA:3.40.50.1820 2 295 1.7E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 Pfam PF00561 alpha/beta hydrolase fold 34 146 1.3E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 PRINTS PR00412 Epoxide hydrolase signature 39 57 4.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 PRINTS PR00412 Epoxide hydrolase signature 106 119 4.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 PRINTS PR00412 Epoxide hydrolase signature 120 133 4.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 PRINTS PR00412 Epoxide hydrolase signature 268 290 4.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SmaCSM2_RS00875 b8c35e5f61b6b08ad085ccbed81dfa1a 296 SUPERFAMILY SSF53474 5 293 1.75E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Gene3D G3DSA:3.90.1170.30 2 54 5.4E-14 T 28-03-2018 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Pfam PF00364 Biotin-requiring enzyme 4 76 1.6E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 SUPERFAMILY SSF52777 170 398 1.33E-91 T 28-03-2018 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 170 397 5.0E-85 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Pfam PF02817 e3 binding domain 122 153 3.0E-6 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Gene3D G3DSA:4.10.320.10 116 164 5.6E-8 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 SUPERFAMILY SSF51230 1 95 1.57E-26 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 SUPERFAMILY SSF47005 116 158 2.75E-7 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 399 2.3E-178 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Gene3D G3DSA:3.30.559.10 165 398 1.4E-93 T 28-03-2018 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 Gene3D G3DSA:2.40.50.100 55 115 1.5E-6 T 28-03-2018 SmaCSM2_RS14125 fb85c94699b66d4395609633515fa32e 400 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SmaCSM2_RS12280 52f6f97f5e385de563e6e75a49f5655f 235 Pfam PF02665 Nitrate reductase gamma subunit 6 225 8.2E-82 T 28-03-2018 IPR023234 NarG-like domain SmaCSM2_RS12280 52f6f97f5e385de563e6e75a49f5655f 235 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 5 226 1.4E-80 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 SmaCSM2_RS12280 52f6f97f5e385de563e6e75a49f5655f 235 SUPERFAMILY SSF103501 5 225 4.18E-65 T 28-03-2018 IPR023234 NarG-like domain SmaCSM2_RS12280 52f6f97f5e385de563e6e75a49f5655f 235 Gene3D G3DSA:1.20.950.20 2 217 3.0E-40 T 28-03-2018 SmaCSM2_RS08085 8feb742552869870cd65599459559c7e 124 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 20 121 3.1E-25 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein SmaCSM2_RS08085 8feb742552869870cd65599459559c7e 124 Gene3D G3DSA:3.40.1230.10 1 122 4.7E-29 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein SmaCSM2_RS08085 8feb742552869870cd65599459559c7e 124 SUPERFAMILY SSF64076 1 122 1.06E-31 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein SmaCSM2_RS00395 aa663c860398341dc7eb48ab5e12940e 288 ProSitePatterns PS01335 Methylglyoxal synthase active site. 216 224 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 SmaCSM2_RS00395 aa663c860398341dc7eb48ab5e12940e 288 Gene3D G3DSA:3.40.50.1380 11 147 3.6E-14 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS00395 aa663c860398341dc7eb48ab5e12940e 288 Gene3D G3DSA:3.40.50.1380 148 287 3.2E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS00395 aa663c860398341dc7eb48ab5e12940e 288 SUPERFAMILY SSF52335 11 136 5.26E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS00395 aa663c860398341dc7eb48ab5e12940e 288 SUPERFAMILY SSF52335 151 283 2.08E-30 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SmaCSM2_RS01225 9fbe716c15313a5c2ad553a592c16b81 118 Pfam PF11367 Protein of unknown function (DUF3168) 10 87 1.4E-11 T 28-03-2018 IPR021508 Tail completion protein SmaCSM2_RS08380 9d447a0f224bc338ed3b22cc09bc8a47 421 Gene3D G3DSA:3.20.20.70 39 389 1.4E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS08380 9d447a0f224bc338ed3b22cc09bc8a47 421 PIRSF PIRSF004640 12 419 5.8E-126 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SmaCSM2_RS08380 9d447a0f224bc338ed3b22cc09bc8a47 421 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 409 5.6E-119 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SmaCSM2_RS08380 9d447a0f224bc338ed3b22cc09bc8a47 421 Pfam PF04551 GcpE protein 22 409 1.4E-108 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SmaCSM2_RS08380 9d447a0f224bc338ed3b22cc09bc8a47 421 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 413 29.293 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SmaCSM2_RS03510 39a841ee1db65a71dad695cec05fe5c8 205 SUPERFAMILY SSF140478 26 179 1.7E-53 T 28-03-2018 IPR023353 LemA-like domain SmaCSM2_RS03510 39a841ee1db65a71dad695cec05fe5c8 205 Gene3D G3DSA:1.20.1440.20 13 192 2.2E-54 T 28-03-2018 SmaCSM2_RS03510 39a841ee1db65a71dad695cec05fe5c8 205 Pfam PF04011 LemA family 10 192 3.0E-65 T 28-03-2018 IPR007156 LemA SmaCSM2_RS07415 144a4ea929710bced431f81d87f1660e 97 Pfam PF13560 Helix-turn-helix domain 24 82 1.4E-11 T 28-03-2018 SmaCSM2_RS07415 144a4ea929710bced431f81d87f1660e 97 SUPERFAMILY SSF47413 23 89 7.32E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS07415 144a4ea929710bced431f81d87f1660e 97 SMART SM00530 28 83 1.3E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS07415 144a4ea929710bced431f81d87f1660e 97 Gene3D G3DSA:1.10.260.40 13 97 6.7E-18 T 28-03-2018 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 362 2.7E-72 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 SUPERFAMILY SSF111369 48 288 4.71E-64 T 28-03-2018 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 281 1.4E-14 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 Gene3D G3DSA:2.40.50.100 159 296 1.9E-4 T 28-03-2018 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 Pfam PF00529 HlyD membrane-fusion protein of T1SS 10 349 6.5E-9 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 Gene3D G3DSA:1.10.287.470 93 158 2.2E-7 T 28-03-2018 SmaCSM2_RS09735 6cd5151d0f12cb20c6ff65f475b12e4c 382 Gene3D G3DSA:2.40.50.100 33 91 4.1E-7 T 28-03-2018 SmaCSM2_RS11430 314da352674f3606576b0aa8d356b972 161 Pfam PF01575 MaoC like domain 31 128 7.7E-19 T 28-03-2018 IPR002539 MaoC-like domain SmaCSM2_RS11430 314da352674f3606576b0aa8d356b972 161 Gene3D G3DSA:3.10.129.10 15 160 1.3E-26 T 28-03-2018 SmaCSM2_RS11430 314da352674f3606576b0aa8d356b972 161 SUPERFAMILY SSF54637 22 154 9.82E-28 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS12865 2c8cbf1af2b48e078eb39e8e71037e3d 213 SUPERFAMILY SSF64288 58 209 3.8E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SmaCSM2_RS12865 2c8cbf1af2b48e078eb39e8e71037e3d 213 Gene3D G3DSA:3.40.1410.10 50 213 4.5E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SmaCSM2_RS13255 7197a778b3d0cae066e9f07f145ebaff 354 Gene3D G3DSA:1.20.5.1070 175 303 0.0086 T 28-03-2018 SmaCSM2_RS13255 7197a778b3d0cae066e9f07f145ebaff 354 TIGRFAM TIGR01834 PHA_synth_III_E: poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit 12 296 5.9E-66 T 28-03-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit SmaCSM2_RS13255 7197a778b3d0cae066e9f07f145ebaff 354 Pfam PF09712 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) 12 293 2.1E-86 T 28-03-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit SmaCSM2_RS11890 b2940dc67dbd787372a18ab6f4dd7e53 231 Pfam PF00005 ABC transporter 27 176 1.2E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS11890 b2940dc67dbd787372a18ab6f4dd7e53 231 SUPERFAMILY SSF52540 3 221 2.34E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11890 b2940dc67dbd787372a18ab6f4dd7e53 231 Gene3D G3DSA:3.40.50.300 2 229 3.0E-47 T 28-03-2018 SmaCSM2_RS11890 b2940dc67dbd787372a18ab6f4dd7e53 231 SMART SM00382 31 224 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS00090 8ba6c0cbfb6c49fd15dfd0645340efa5 363 Gene3D G3DSA:3.20.20.70 38 327 2.2E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00090 8ba6c0cbfb6c49fd15dfd0645340efa5 363 SUPERFAMILY SSF102114 57 273 3.27E-12 T 28-03-2018 SmaCSM2_RS00090 8ba6c0cbfb6c49fd15dfd0645340efa5 363 Pfam PF04055 Radical SAM superfamily 77 255 1.6E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS00090 8ba6c0cbfb6c49fd15dfd0645340efa5 363 SMART SM00729 73 298 0.0012 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS14580 e58d2ca3c4d5d3f45f0eee3566357a8d 156 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 14 151 8.8E-42 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 SmaCSM2_RS14580 e58d2ca3c4d5d3f45f0eee3566357a8d 156 Pfam PF13994 PgaD-like protein 14 148 7.0E-40 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 SmaCSM2_RS21655 aac2b582095ca985095b4ad5d842f560 338 PRINTS PR01805 VacJ lipoprotein signature 115 128 4.5E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 SmaCSM2_RS21655 aac2b582095ca985095b4ad5d842f560 338 PRINTS PR01805 VacJ lipoprotein signature 132 148 4.5E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 SmaCSM2_RS21655 aac2b582095ca985095b4ad5d842f560 338 PRINTS PR01805 VacJ lipoprotein signature 183 200 4.5E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 SmaCSM2_RS21655 aac2b582095ca985095b4ad5d842f560 338 PRINTS PR01805 VacJ lipoprotein signature 219 236 4.5E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 SmaCSM2_RS21655 aac2b582095ca985095b4ad5d842f560 338 Pfam PF04333 MlaA lipoprotein 114 305 9.9E-73 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 SmaCSM2_RS00960 9e793222bfcd992e883cd2a21aec5b12 718 Gene3D G3DSA:1.20.1050.40 48 183 1.0E-38 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal SmaCSM2_RS00960 9e793222bfcd992e883cd2a21aec5b12 718 SUPERFAMILY SSF55486 43 716 2.14E-178 T 28-03-2018 SmaCSM2_RS00960 9e793222bfcd992e883cd2a21aec5b12 718 Pfam PF01432 Peptidase family M3 270 713 8.8E-131 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SmaCSM2_RS00960 9e793222bfcd992e883cd2a21aec5b12 718 Gene3D G3DSA:1.10.1370.10 496 718 1.5E-57 T 28-03-2018 SmaCSM2_RS00960 9e793222bfcd992e883cd2a21aec5b12 718 Gene3D G3DSA:1.10.1370.10 184 442 5.1E-38 T 28-03-2018 SmaCSM2_RS13720 1fbbfd1df4e513495c4f5c5e72daa047 478 Pfam PF00144 Beta-lactamase 36 348 4.9E-50 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS13720 1fbbfd1df4e513495c4f5c5e72daa047 478 Gene3D G3DSA:1.25.40.10 378 477 4.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS13720 1fbbfd1df4e513495c4f5c5e72daa047 478 Gene3D G3DSA:3.40.710.10 18 369 9.3E-71 T 28-03-2018 SmaCSM2_RS13720 1fbbfd1df4e513495c4f5c5e72daa047 478 SUPERFAMILY SSF56601 27 330 8.05E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS15205 b30fe380ff9729d91470f2e855da0c35 381 SUPERFAMILY SSF53756 6 374 3.3E-69 T 28-03-2018 SmaCSM2_RS15205 b30fe380ff9729d91470f2e855da0c35 381 Gene3D G3DSA:3.40.50.2000 1 179 2.1E-19 T 28-03-2018 SmaCSM2_RS15205 b30fe380ff9729d91470f2e855da0c35 381 Gene3D G3DSA:3.40.50.2000 180 355 8.7E-40 T 28-03-2018 SmaCSM2_RS15205 b30fe380ff9729d91470f2e855da0c35 381 Pfam PF13439 Glycosyltransferase Family 4 16 160 2.7E-16 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SmaCSM2_RS15205 b30fe380ff9729d91470f2e855da0c35 381 Pfam PF00534 Glycosyl transferases group 1 186 348 6.8E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SmaCSM2_RS06515 f2b6695528fc41ea9cfba6a3b3ff4073 262 Pfam PF14257 Domain of unknown function (DUF4349) 20 247 6.6E-28 T 28-03-2018 IPR025645 Domain of unknown function DUF4349 SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 Gene3D G3DSA:3.30.428.10 1 111 4.6E-29 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 Pfam PF01230 HIT domain 12 108 1.2E-24 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 ProSitePatterns PS00892 HIT domain signature. 89 107 - T 28-03-2018 IPR019808 Histidine triad, conserved site SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 PRINTS PR00332 Histidine triad family signature 27 45 1.8E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 PRINTS PR00332 Histidine triad family signature 6 22 1.8E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 PRINTS PR00332 Histidine triad family signature 96 106 1.8E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SmaCSM2_RS04740 84e427ba6904b940cf840f2144b50841 119 SUPERFAMILY SSF54197 1 110 2.98E-33 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SmaCSM2_RS01460 b5c3237a06ff83bd168dc127210240a0 415 Gene3D G3DSA:1.20.1600.10 40 379 4.4E-26 T 28-03-2018 SmaCSM2_RS01460 b5c3237a06ff83bd168dc127210240a0 415 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 410 2.9E-51 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS01460 b5c3237a06ff83bd168dc127210240a0 415 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 82 322 7.7E-20 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS01460 b5c3237a06ff83bd168dc127210240a0 415 SUPERFAMILY SSF111369 77 327 9.81E-23 T 28-03-2018 SmaCSM2_RS20655 c284fedc1657fc8e8ff0b175b93f2757 259 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 1 250 40.059 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 SmaCSM2_RS20655 c284fedc1657fc8e8ff0b175b93f2757 259 Pfam PF12697 Alpha/beta hydrolase family 12 244 7.4E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS20655 c284fedc1657fc8e8ff0b175b93f2757 259 Gene3D G3DSA:3.40.50.1820 1 252 1.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20655 c284fedc1657fc8e8ff0b175b93f2757 259 SUPERFAMILY SSF53474 1 250 2.9E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20655 c284fedc1657fc8e8ff0b175b93f2757 259 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 7 249 1.8E-87 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 SmaCSM2_RS06940 68e8f8e2992a07604271c5e885a34ef5 188 Gene3D G3DSA:3.40.80.10 21 185 1.5E-29 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS06940 68e8f8e2992a07604271c5e885a34ef5 188 SUPERFAMILY SSF55846 23 181 1.83E-33 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS06940 68e8f8e2992a07604271c5e885a34ef5 188 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 28 171 6.3E-23 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS06940 68e8f8e2992a07604271c5e885a34ef5 188 SMART SM00644 18 155 4.4E-16 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS15740 296d055fa4f94973c599b8d9e869c81c 47 Pfam PF09791 Oxidoreductase-like protein, N-terminal 2 39 1.2E-13 T 28-03-2018 IPR019180 Oxidoreductase-like, N-terminal SmaCSM2_RS12915 4a186f6f2d4f02c3200b75a52ad95a33 552 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 7 545 3.4E-224 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SmaCSM2_RS12915 4a186f6f2d4f02c3200b75a52ad95a33 552 Pfam PF02652 L-lactate permease 16 541 9.8E-216 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SmaCSM2_RS18730 372c43d2c48da1f5f472f059a13ac908 272 SUPERFAMILY SSF56935 40 145 3.87E-6 T 28-03-2018 SmaCSM2_RS18730 372c43d2c48da1f5f472f059a13ac908 272 SUPERFAMILY SSF56935 173 271 3.87E-6 T 28-03-2018 SmaCSM2_RS18730 372c43d2c48da1f5f472f059a13ac908 272 Gene3D G3DSA:2.40.160.20 28 213 8.7E-7 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS18730 372c43d2c48da1f5f472f059a13ac908 272 Gene3D G3DSA:2.40.160.20 214 272 0.0015 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 Gene3D G3DSA:3.40.50.1820 5 282 5.8E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 Pfam PF00561 alpha/beta hydrolase fold 51 150 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 SUPERFAMILY SSF53474 21 272 1.29E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS09180 a93e86ed9c097ad6335bac836007321d 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 4.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 Pfam PF06144 DNA polymerase III, delta subunit 21 190 2.2E-21 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 Gene3D G3DSA:1.20.272.10 221 340 2.6E-18 T 28-03-2018 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 333 1.3E-95 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 Gene3D G3DSA:1.10.8.60 144 220 3.2E-24 T 28-03-2018 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 SUPERFAMILY SSF52540 2 210 3.77E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 Gene3D G3DSA:3.40.50.300 1 138 2.2E-18 T 28-03-2018 SmaCSM2_RS15620 b6adfbc5945e4269f35af454988eb865 345 SUPERFAMILY SSF48019 212 334 6.12E-21 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 SUPERFAMILY SSF100939 2 268 1.86E-48 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 178 6.3E-29 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 266 6.7E-96 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 Gene3D G3DSA:2.40.290.10 2 183 2.5E-28 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 PIRSF PIRSF006493 1 301 2.9E-85 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 SMART SM00559 53 181 1.3E-24 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SmaCSM2_RS00215 c8a01cd46ba650129fc15354823f4d23 306 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 263 30.668 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SmaCSM2_RS10425 1fd6c5378c51f20272bc2bea9511690b 422 Gene3D G3DSA:2.30.320.10 208 421 1.2E-9 T 28-03-2018 SmaCSM2_RS16155 733e8df8b648133643857324c36ff9a8 160 SUPERFAMILY SSF52833 1 157 1.47E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS16155 733e8df8b648133643857324c36ff9a8 160 Pfam PF08534 Redoxin 5 155 7.3E-33 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SmaCSM2_RS16155 733e8df8b648133643857324c36ff9a8 160 Gene3D G3DSA:3.40.30.10 1 158 9.5E-27 T 28-03-2018 SmaCSM2_RS13560 34d4e31c43ba87041b57094e018b8888 115 Pfam PF01638 HxlR-like helix-turn-helix 20 106 3.2E-34 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SmaCSM2_RS13560 34d4e31c43ba87041b57094e018b8888 115 Gene3D G3DSA:1.10.10.10 18 110 3.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13560 34d4e31c43ba87041b57094e018b8888 115 SUPERFAMILY SSF46785 10 105 6.42E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12450 2c920508d357db7aa87d2a1b3caffb32 217 Pfam PF11828 Protein of unknown function (DUF3348) 5 179 1.9E-46 T 28-03-2018 IPR021783 Protein of unknown function DUF3348 SmaCSM2_RS12450 2c920508d357db7aa87d2a1b3caffb32 217 Pfam PF11828 Protein of unknown function (DUF3348) 182 215 4.6E-10 T 28-03-2018 IPR021783 Protein of unknown function DUF3348 SmaCSM2_RS18130 227907979b089934985b930945047d1e 291 SUPERFAMILY SSF103481 44 133 4.05E-6 T 28-03-2018 SmaCSM2_RS18130 227907979b089934985b930945047d1e 291 SUPERFAMILY SSF103481 185 276 7.19E-7 T 28-03-2018 SmaCSM2_RS18130 227907979b089934985b930945047d1e 291 Pfam PF00892 EamA-like transporter family 146 275 1.2E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS02585 d3599d42591dd23ed5b737832ac0d55a 115 Pfam PF09361 Phasin protein 8 103 1.9E-9 T 28-03-2018 IPR018968 Phasin SmaCSM2_RS19090 4b9d673462ca251d236ebca3663273e3 196 Pfam PF01300 Telomere recombination 22 192 2.4E-39 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 SmaCSM2_RS19090 4b9d673462ca251d236ebca3663273e3 196 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 13 195 38.665 T 28-03-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 SmaCSM2_RS19090 4b9d673462ca251d236ebca3663273e3 196 Gene3D G3DSA:3.90.870.10 9 195 2.9E-51 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SmaCSM2_RS19090 4b9d673462ca251d236ebca3663273e3 196 SUPERFAMILY SSF55821 16 194 1.07E-49 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 Gene3D G3DSA:3.30.110.60 4 100 2.4E-24 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 5 100 2.1E-26 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 100 5.0E-40 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 88 4.5E-20 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 SUPERFAMILY SSF75471 4 98 4.58E-27 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SmaCSM2_RS08090 ceed3c8810fe82953054a003ced73b56 101 SMART SM01103 5 88 2.6E-34 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SmaCSM2_RS20820 c1704049660a713e33180a2c4431ee1c 305 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 280 3.6E-66 T 28-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 SmaCSM2_RS19770 43474a6226d2273daffa13fdcebdd63c 129 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 94 6.0E-22 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 SmaCSM2_RS19770 43474a6226d2273daffa13fdcebdd63c 129 Pfam PF03334 Na+/H+ antiporter subunit 12 92 1.3E-24 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 SmaCSM2_RS19740 49586512c23317a5772c0a066d4ed764 161 Pfam PF06127 Protein of unknown function (DUF962) 10 156 2.2E-25 T 28-03-2018 IPR009305 Protein of unknown function DUF962 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 Gene3D G3DSA:2.30.40.10 42 110 5.8E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 Gene3D G3DSA:3.20.20.140 111 516 1.5E-38 T 28-03-2018 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 SUPERFAMILY SSF51338 533 577 1.65E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 SUPERFAMILY SSF51338 35 102 1.65E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 Gene3D G3DSA:2.30.40.10 517 581 1.7E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 Pfam PF07969 Amidohydrolase family 91 574 1.8E-122 T 28-03-2018 IPR013108 Amidohydrolase 3 SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 SUPERFAMILY SSF51556 101 163 2.29E-45 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS12795 ca77b1b8a4cf46eaa554ea6a8baf17d5 656 SUPERFAMILY SSF51556 243 534 2.29E-45 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS13245 46a0aa3dd31cb1fa692cf8a12e701c83 124 Pfam PF17263 Family of unknown function (DUF5329) 28 120 1.2E-34 T 28-03-2018 IPR035242 Protein of unknown function DUF5329 SmaCSM2_RS13245 46a0aa3dd31cb1fa692cf8a12e701c83 124 ProDom PD031420 YFEK EXPORTED PRECURSOR SIGNAL PERIPLASMIC ECS3291 XCC0326 30 102 4.0E-21 T 28-03-2018 IPR035242 Protein of unknown function DUF5329 SmaCSM2_RS01965 2890a13199fcdfb1a0a322ec1001bfd1 196 SUPERFAMILY SSF109854 33 176 4.58E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SmaCSM2_RS01965 2890a13199fcdfb1a0a322ec1001bfd1 196 Gene3D G3DSA:1.20.120.450 28 196 2.9E-29 T 28-03-2018 SmaCSM2_RS01965 2890a13199fcdfb1a0a322ec1001bfd1 196 Pfam PF05163 DinB family 33 193 5.9E-34 T 28-03-2018 IPR007837 DNA damage-inducible protein DinB SmaCSM2_RS04650 40c263067eb7e2cc14559ad9719013a6 129 Gene3D G3DSA:4.10.430.10 80 110 2.7E-8 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS04650 40c263067eb7e2cc14559ad9719013a6 129 SMART SM00528 74 117 1.5E-9 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 SmaCSM2_RS04650 40c263067eb7e2cc14559ad9719013a6 129 SUPERFAMILY SSF81273 78 107 2.63E-6 T 28-03-2018 SmaCSM2_RS04650 40c263067eb7e2cc14559ad9719013a6 129 Pfam PF00816 H-NS histone family 15 107 1.3E-19 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 SmaCSM2_RS06925 7e5e5e3d80df7ae26b7b97293197df74 233 Gene3D G3DSA:3.10.50.40 117 233 1.2E-17 T 28-03-2018 SmaCSM2_RS06925 7e5e5e3d80df7ae26b7b97293197df74 233 Gene3D G3DSA:1.10.287.460 19 116 1.3E-22 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS06925 7e5e5e3d80df7ae26b7b97293197df74 233 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 17 135 1.7E-28 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS06925 7e5e5e3d80df7ae26b7b97293197df74 233 SUPERFAMILY SSF54534 28 233 5.11E-35 T 28-03-2018 SmaCSM2_RS06925 7e5e5e3d80df7ae26b7b97293197df74 233 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 144 230 5.0E-8 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SmaCSM2_RS07455 b99fe68674d56c80b6416f6674424344 202 Gene3D G3DSA:3.40.630.30 9 200 1.6E-12 T 28-03-2018 SmaCSM2_RS07455 b99fe68674d56c80b6416f6674424344 202 SUPERFAMILY SSF55729 19 170 1.04E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS00770 ee27af88aa8457ef9622ecbd21ee8169 255 SMART SM00342 166 250 1.6E-6 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS00770 ee27af88aa8457ef9622ecbd21ee8169 255 Pfam PF12833 Helix-turn-helix domain 172 250 8.7E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS00770 ee27af88aa8457ef9622ecbd21ee8169 255 Gene3D G3DSA:1.10.10.60 203 253 1.3E-5 T 28-03-2018 SmaCSM2_RS00770 ee27af88aa8457ef9622ecbd21ee8169 255 Gene3D G3DSA:1.10.10.60 128 202 3.9E-6 T 28-03-2018 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 Pfam PF00573 Ribosomal protein L4/L1 family 12 198 1.6E-53 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 201 28.718 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 Gene3D G3DSA:3.40.1370.10 6 138 1.8E-36 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 Gene3D G3DSA:3.40.1370.10 139 199 4.5E-13 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 12 198 6.1E-62 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS03995 2c75e0a1d9e4a7cbe1af2f794c170aa5 201 SUPERFAMILY SSF52166 10 200 7.72E-61 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SmaCSM2_RS14610 3241b2af8a61c6a71c58ae30a852eed1 200 Pfam PF13302 Acetyltransferase (GNAT) domain 18 156 1.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS14610 3241b2af8a61c6a71c58ae30a852eed1 200 Gene3D G3DSA:3.40.630.30 3 198 4.2E-30 T 28-03-2018 SmaCSM2_RS14610 3241b2af8a61c6a71c58ae30a852eed1 200 SUPERFAMILY SSF55729 8 181 4.1E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 PIRSF PIRSF002849 2 328 1.9E-127 T 28-03-2018 SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 1.7E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 SUPERFAMILY SSF52540 17 302 9.31E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 Gene3D G3DSA:1.10.8.300 215 323 5.0E-33 T 28-03-2018 SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 Gene3D G3DSA:3.40.50.300 30 196 6.1E-30 T 28-03-2018 SmaCSM2_RS20750 d19fb4cb2f948051cb1e08715ddd47c0 328 SMART SM00382 46 281 1.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08550 e5d19cdc5ea18fd03db0702f192f7a0e 210 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 9.9E-82 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SmaCSM2_RS08550 e5d19cdc5ea18fd03db0702f192f7a0e 210 Gene3D G3DSA:3.40.50.2020 1 206 2.5E-59 T 28-03-2018 SmaCSM2_RS08550 e5d19cdc5ea18fd03db0702f192f7a0e 210 SUPERFAMILY SSF53271 4 206 2.75E-64 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS08550 e5d19cdc5ea18fd03db0702f192f7a0e 210 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 42.539 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SmaCSM2_RS08550 e5d19cdc5ea18fd03db0702f192f7a0e 210 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 3.1E-64 T 28-03-2018 SmaCSM2_RS13020 a9b492508e61630619edc423cbc51828 233 Gene3D G3DSA:3.40.50.880 1 227 1.6E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS13020 a9b492508e61630619edc423cbc51828 233 Pfam PF00117 Glutamine amidotransferase class-I 25 182 1.6E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS13020 a9b492508e61630619edc423cbc51828 233 SUPERFAMILY SSF52317 25 226 2.6E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS18650 07118aacbe8caf485185b3c0073b35ef 433 Pfam PF02687 FtsX-like permease family 337 425 7.4E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS18650 07118aacbe8caf485185b3c0073b35ef 433 Pfam PF12704 MacB-like periplasmic core domain 20 218 4.8E-22 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS10405 cb60de598150511ea3764e902cbf0eef 95 SUPERFAMILY SSF47413 7 88 1.29E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS10405 cb60de598150511ea3764e902cbf0eef 95 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 82 7.4E-27 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 SmaCSM2_RS10405 cb60de598150511ea3764e902cbf0eef 95 Gene3D G3DSA:1.10.260.40 1 82 1.6E-8 T 28-03-2018 SmaCSM2_RS10405 cb60de598150511ea3764e902cbf0eef 95 Pfam PF01381 Helix-turn-helix 20 57 3.6E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS06500 bff95f2194dd241467cdc2148388e08d 332 SUPERFAMILY SSF48230 22 321 2.84E-43 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SmaCSM2_RS06500 bff95f2194dd241467cdc2148388e08d 332 Pfam PF05426 Alginate lyase 39 270 8.9E-54 T 28-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SmaCSM2_RS06500 bff95f2194dd241467cdc2148388e08d 332 Gene3D G3DSA:1.50.10.100 15 325 9.1E-44 T 28-03-2018 SmaCSM2_RS08965 9f5477e182bd4298584607cb3c468481 295 Pfam PF00795 Carbon-nitrogen hydrolase 8 272 1.6E-56 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS08965 9f5477e182bd4298584607cb3c468481 295 Gene3D G3DSA:3.60.110.10 1 295 2.0E-82 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS08965 9f5477e182bd4298584607cb3c468481 295 SUPERFAMILY SSF56317 6 292 1.57E-87 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 Gene3D G3DSA:1.20.58.220 4 116 1.2E-26 T 28-03-2018 SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 Pfam PF01895 PhoU domain 23 109 6.5E-20 T 28-03-2018 IPR026022 PhoU domain SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 Pfam PF01895 PhoU domain 126 209 1.2E-16 T 28-03-2018 IPR026022 PhoU domain SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 10 218 3.5E-60 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 PIRSF PIRSF003107 5 221 9.0E-59 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 Gene3D G3DSA:1.20.58.220 121 234 1.3E-25 T 28-03-2018 SmaCSM2_RS06875 f409ea2f78db0d1c0b98e8940a6e79a2 235 SUPERFAMILY SSF109755 10 226 1.78E-65 T 28-03-2018 SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 Pfam PF00263 Bacterial type II and III secretion system protein 309 464 1.6E-40 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 PRINTS PR00811 Bacterial general secretion pathway protein D signature 304 328 1.7E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 PRINTS PR00811 Bacterial general secretion pathway protein D signature 429 447 1.7E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 PRINTS PR00811 Bacterial general secretion pathway protein D signature 343 353 1.7E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 PRINTS PR00811 Bacterial general secretion pathway protein D signature 452 466 1.7E-11 T 28-03-2018 IPR001775 GspD/PilQ family SmaCSM2_RS04575 ef04c02b92338e0deea4ecfa32f847e3 498 Pfam PF13629 Pilus formation protein N terminal region 94 155 1.2E-12 T 28-03-2018 IPR032789 Pilus formation protein, N-terminal SmaCSM2_RS08960 460a7c1f90c4d5a95bb970bcf0ddc962 176 Pfam PF13420 Acetyltransferase (GNAT) domain 5 158 1.7E-27 T 28-03-2018 SmaCSM2_RS08960 460a7c1f90c4d5a95bb970bcf0ddc962 176 Gene3D G3DSA:3.40.630.30 2 176 2.9E-35 T 28-03-2018 SmaCSM2_RS08960 460a7c1f90c4d5a95bb970bcf0ddc962 176 SUPERFAMILY SSF55729 5 167 5.4E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS07785 874b8fbe7f199c3196cd5b33288d9517 549 TIGRFAM TIGR03764 ICE_PFGI_1_parB: integrating conjugative element, PFGI_1 class, ParB family protein 28 290 1.9E-122 T 28-03-2018 IPR022304 Integrating conjugative element, PFGI-1, ParB SmaCSM2_RS07785 874b8fbe7f199c3196cd5b33288d9517 549 SUPERFAMILY SSF110849 37 159 2.54E-10 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SmaCSM2_RS07785 874b8fbe7f199c3196cd5b33288d9517 549 Gene3D G3DSA:3.90.1530.10 31 144 4.5E-14 T 28-03-2018 SmaCSM2_RS07785 874b8fbe7f199c3196cd5b33288d9517 549 Pfam PF02195 ParB-like nuclease domain 39 102 1.4E-4 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SmaCSM2_RS07785 874b8fbe7f199c3196cd5b33288d9517 549 Gene3D G3DSA:1.10.10.10 162 195 4.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20735 9e26e4b8fa7cd97b3ac5ce943e86db9c 330 Pfam PF01944 Stage II sporulation protein M 118 294 7.1E-35 T 28-03-2018 IPR002798 Stage II sporulation protein M-like SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 SUPERFAMILY SSF55120 66 230 2.55E-8 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 SMART SM00363 4 69 2.6E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 SUPERFAMILY SSF55174 4 74 1.15E-11 T 28-03-2018 SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 Pfam PF01479 S4 domain 5 50 3.6E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 Gene3D G3DSA:3.10.290.10 1 61 4.0E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS15815 1b68e4efbca02e2d4accedccfbb4900b 232 Gene3D G3DSA:3.30.2350.10 62 232 1.1E-10 T 28-03-2018 SmaCSM2_RS02545 c8e72eb8c564e764b23e7eeef51bb82b 245 SUPERFAMILY SSF55068 59 225 5.49E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02545 c8e72eb8c564e764b23e7eeef51bb82b 245 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 61 221 34.227 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02545 c8e72eb8c564e764b23e7eeef51bb82b 245 Pfam PF01625 Peptide methionine sulfoxide reductase 64 215 3.1E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02545 c8e72eb8c564e764b23e7eeef51bb82b 245 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 64 212 2.5E-51 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02545 c8e72eb8c564e764b23e7eeef51bb82b 245 Gene3D G3DSA:3.30.1060.10 60 233 1.5E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 Gene3D G3DSA:3.90.1150.10 23 106 3.3E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 Gene3D G3DSA:3.90.1150.10 282 400 1.4E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 5 398 53.379 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 Pfam PF00155 Aminotransferase class I and II 46 390 7.2E-68 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 9 400 3.8E-222 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 Gene3D G3DSA:3.40.640.10 107 281 5.9E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS04235 661240676dcf857bf5a8ecf07202599b 402 SUPERFAMILY SSF53383 9 397 4.47E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 Gene3D G3DSA:1.10.10.10 232 372 3.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 1.7E-16 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 PRINTS PR00045 Sigma-54 factor signature 182 199 5.5E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 PRINTS PR00045 Sigma-54 factor signature 372 384 5.5E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 PRINTS PR00045 Sigma-54 factor signature 388 399 5.5E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 PRINTS PR00045 Sigma-54 factor signature 446 464 5.5E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 360 379 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 Pfam PF04963 Sigma-54 factor, core binding domain 107 300 3.3E-49 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 Gene3D G3DSA:1.10.260.40 373 462 1.9E-7 T 28-03-2018 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 PIRSF PIRSF000774 1 473 3.2E-131 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 Pfam PF04552 Sigma-54, DNA binding domain 314 471 5.0E-63 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 451 458 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05100 5a874f238851a99f081e4213a551fe78 473 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 469 5.2E-141 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS14070 210fc7a11233230908d5252bb7f2f317 119 SUPERFAMILY SSF46785 5 79 2.86E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14070 210fc7a11233230908d5252bb7f2f317 119 SMART SM00345 16 75 1.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS14070 210fc7a11233230908d5252bb7f2f317 119 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SmaCSM2_RS14070 210fc7a11233230908d5252bb7f2f317 119 Gene3D G3DSA:1.10.10.10 6 80 6.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14070 210fc7a11233230908d5252bb7f2f317 119 Gene3D G3DSA:1.10.287.100 81 116 1.0E-9 T 28-03-2018 SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 5 245 42.148 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 SUPERFAMILY SSF55729 83 242 2.52E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 Gene3D G3DSA:3.40.630.30 78 235 3.5E-10 T 28-03-2018 SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 PIRSF PIRSF037208 4 250 2.1E-86 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 111 236 4.3E-37 T 28-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 SmaCSM2_RS05840 ad84708c815794b8d15931ea874e1580 251 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 19 89 8.1E-16 T 28-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 SmaCSM2_RS09250 62d7f6a860c0fea6da5a2a6db84d3d09 193 Gene3D G3DSA:3.40.50.360 2 185 8.3E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS09250 62d7f6a860c0fea6da5a2a6db84d3d09 193 SUPERFAMILY SSF52218 1 178 1.92E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS09250 62d7f6a860c0fea6da5a2a6db84d3d09 193 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 6 179 6.8E-68 T 28-03-2018 IPR019912 FMN reductase, MsuE-like KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 SmaCSM2_RS09250 62d7f6a860c0fea6da5a2a6db84d3d09 193 Pfam PF03358 NADPH-dependent FMN reductase 6 152 5.0E-29 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS07840 be87bc4093273eb156cdfe36cc5014e1 254 SUPERFAMILY SSF54637 120 253 4.11E-9 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS07840 be87bc4093273eb156cdfe36cc5014e1 254 Pfam PF13622 Thioesterase-like superfamily 21 251 2.5E-29 T 28-03-2018 SmaCSM2_RS07840 be87bc4093273eb156cdfe36cc5014e1 254 Gene3D G3DSA:3.10.129.10 29 114 0.0035 T 28-03-2018 SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 184 0.0014 T 28-03-2018 SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 Gene3D G3DSA:3.40.50.720 1 223 3.5E-55 T 28-03-2018 SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 Pfam PF00106 short chain dehydrogenase 4 188 6.2E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS01585 f6c51d04dcdac9c5086461a95951c17e 250 SUPERFAMILY SSF51735 3 225 6.56E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 PIRSF PIRSF029342 202 250 0.0015 T 28-03-2018 IPR016915 Uncharacterised conserved protein UCP029342 SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 PIRSF PIRSF029342 269 354 6.9 T 28-03-2018 IPR016915 Uncharacterised conserved protein UCP029342 SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 PIRSF PIRSF029342 7 210 1.9E-79 T 28-03-2018 IPR016915 Uncharacterised conserved protein UCP029342 SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 Pfam PF03734 L,D-transpeptidase catalytic domain 66 173 2.1E-22 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 SUPERFAMILY SSF141523 63 173 1.57E-31 T 28-03-2018 SmaCSM2_RS05220 03b9aa77c1350ace28881f3b5b58f115 361 Gene3D G3DSA:2.40.440.10 59 175 2.4E-28 T 28-03-2018 SmaCSM2_RS08705 e33dad83fd6bf24fe9a06286a553227d 141 Gene3D G3DSA:3.30.530.20 1 140 4.7E-29 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS08705 e33dad83fd6bf24fe9a06286a553227d 141 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 8.6E-29 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SmaCSM2_RS08705 e33dad83fd6bf24fe9a06286a553227d 141 SUPERFAMILY SSF55961 1 140 3.17E-34 T 28-03-2018 SmaCSM2_RS18355 bdd8d678e2a5c893a9e1223ea12a2afe 367 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 320 344 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SmaCSM2_RS18355 bdd8d678e2a5c893a9e1223ea12a2afe 367 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 21 362 6.7E-111 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 SmaCSM2_RS18355 bdd8d678e2a5c893a9e1223ea12a2afe 367 Pfam PF01098 Cell cycle protein 53 361 4.3E-91 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SmaCSM2_RS10560 3b337f3775c494e54a782c109d146b36 255 Pfam PF07103 Protein of unknown function (DUF1365) 6 249 5.4E-71 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 SmaCSM2_RS06945 f16f754f3d51e5df8aca8b574fdbda54 175 SUPERFAMILY SSF53474 4 173 2.36E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS06945 f16f754f3d51e5df8aca8b574fdbda54 175 Gene3D G3DSA:3.40.50.1820 2 175 3.5E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05805 c105ed6c7cba27097abb6f6b370ecd1c 269 Gene3D G3DSA:3.30.1380.10 130 264 8.2E-26 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SmaCSM2_RS05805 c105ed6c7cba27097abb6f6b370ecd1c 269 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 142 266 5.9E-35 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 SmaCSM2_RS05805 c105ed6c7cba27097abb6f6b370ecd1c 269 SUPERFAMILY SSF55166 138 266 4.97E-24 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 SUPERFAMILY SSF55874 324 471 2.36E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 Gene3D G3DSA:3.30.565.10 205 472 3.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 SUPERFAMILY SSF47384 242 306 2.75E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 SMART SM00387 361 474 2.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS01320 255e3bf3fafddc17bbf04f854f75c320 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 472 4.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS21280 3b4fe5ca147a0b5a97e4256fe44d97d4 169 Gene3D G3DSA:3.30.420.10 1 169 6.4E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS21280 3b4fe5ca147a0b5a97e4256fe44d97d4 169 Pfam PF00929 Exonuclease 5 164 1.4E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS21280 3b4fe5ca147a0b5a97e4256fe44d97d4 169 SUPERFAMILY SSF53098 3 167 8.54E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS21280 3b4fe5ca147a0b5a97e4256fe44d97d4 169 SMART SM00479 3 169 8.4E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SmaCSM2_RS21280 3b4fe5ca147a0b5a97e4256fe44d97d4 169 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 164 5.7E-43 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS05825 ae2a08be87f90b3d3765250a23a339fe 293 Pfam PF01145 SPFH domain / Band 7 family 66 237 1.2E-27 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS05825 ae2a08be87f90b3d3765250a23a339fe 293 SUPERFAMILY SSF117892 100 228 2.22E-13 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS05825 ae2a08be87f90b3d3765250a23a339fe 293 SMART SM00244 62 226 8.5E-11 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS04890 052ca44d441e0f8371b0e44d1fa3d4db 224 Gene3D G3DSA:3.40.50.150 4 223 2.5E-27 T 28-03-2018 SmaCSM2_RS04890 052ca44d441e0f8371b0e44d1fa3d4db 224 SUPERFAMILY SSF53335 10 222 6.49E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS04890 052ca44d441e0f8371b0e44d1fa3d4db 224 Pfam PF13649 Methyltransferase domain 45 138 1.0E-10 T 28-03-2018 SmaCSM2_RS16350 7f2116cfd2d043262cedaa63a7c5e95f 249 SUPERFAMILY SSF53955 50 241 4.5E-59 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS16350 7f2116cfd2d043262cedaa63a7c5e95f 249 Pfam PF00912 Transglycosylase 72 235 1.1E-46 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16350 7f2116cfd2d043262cedaa63a7c5e95f 249 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 19 243 43.931 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 SmaCSM2_RS16350 7f2116cfd2d043262cedaa63a7c5e95f 249 Gene3D G3DSA:1.10.3810.10 54 247 6.2E-54 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SmaCSM2_RS16350 7f2116cfd2d043262cedaa63a7c5e95f 249 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 27 240 1.4E-80 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 SmaCSM2_RS01690 85f7dd4726e9cfe3e7211562160df1e6 490 Gene3D G3DSA:2.70.70.10 250 426 8.7E-43 T 28-03-2018 SmaCSM2_RS01690 85f7dd4726e9cfe3e7211562160df1e6 490 Pfam PF04225 Opacity-associated protein A LysM-like domain 101 169 2.2E-6 T 28-03-2018 IPR007340 Opacity-associated protein A SmaCSM2_RS01690 85f7dd4726e9cfe3e7211562160df1e6 490 Pfam PF01551 Peptidase family M23 325 421 2.4E-33 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS01690 85f7dd4726e9cfe3e7211562160df1e6 490 SUPERFAMILY SSF51261 177 422 5.75E-72 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS14240 c06358d0cff123dd825515b3c454a72a 113 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 113 2.8E-38 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 SmaCSM2_RS14240 c06358d0cff123dd825515b3c454a72a 113 SUPERFAMILY SSF52833 2 113 1.22E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14240 c06358d0cff123dd825515b3c454a72a 113 Pfam PF03960 ArsC family 10 112 1.4E-15 T 28-03-2018 IPR006660 Arsenate reductase-like SmaCSM2_RS14240 c06358d0cff123dd825515b3c454a72a 113 Gene3D G3DSA:3.40.30.10 1 113 2.1E-31 T 28-03-2018 SmaCSM2_RS12650 ae07e37df8e6006ee677200eb42a06f1 117 Pfam PF00893 Small Multidrug Resistance protein 13 103 1.3E-20 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SmaCSM2_RS12650 ae07e37df8e6006ee677200eb42a06f1 117 SUPERFAMILY SSF103481 17 115 2.62E-15 T 28-03-2018 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 SUPERFAMILY SSF48498 90 192 1.29E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 SUPERFAMILY SSF46689 13 78 9.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 8.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 Gene3D G3DSA:1.10.10.60 1 59 3.5E-19 T 28-03-2018 SmaCSM2_RS16370 df0a6c071e52ae9acda08cb1e45f15c7 200 Gene3D G3DSA:1.10.10.60 60 195 5.2E-11 T 28-03-2018 SmaCSM2_RS06385 cdb35aa96f19b4a45e7cbcfae2a883e6 734 Pfam PF00593 TonB dependent receptor 284 731 8.2E-43 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06385 cdb35aa96f19b4a45e7cbcfae2a883e6 734 SUPERFAMILY SSF56935 45 734 7.94E-94 T 28-03-2018 SmaCSM2_RS06385 cdb35aa96f19b4a45e7cbcfae2a883e6 734 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 161 1.6E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06385 cdb35aa96f19b4a45e7cbcfae2a883e6 734 Gene3D G3DSA:2.40.170.20 175 734 5.1E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06385 cdb35aa96f19b4a45e7cbcfae2a883e6 734 Gene3D G3DSA:2.170.130.10 36 166 1.7E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PIRSF PIRSF002560 1 156 7.3E-70 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.3E-71 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 Gene3D G3DSA:1.20.1260.10 1 76 8.1E-18 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 Gene3D G3DSA:1.20.5.420 85 138 1.1E-21 T 28-03-2018 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 SUPERFAMILY SSF47240 1 153 4.06E-53 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 Pfam PF00210 Ferritin-like domain 8 144 2.5E-38 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 44 64 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 107 127 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 128 149 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 86 106 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 23 43 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 3 22 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS19625 c62126f9fcdfa321eebac76039e79450 156 PRINTS PR00601 Bacterioferritin signature 65 85 2.7E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SmaCSM2_RS21530 742cf41e63005514fa7ce516f2e4cefc 296 SUPERFAMILY SSF74650 7 281 9.42E-57 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SmaCSM2_RS21530 742cf41e63005514fa7ce516f2e4cefc 296 PIRSF PIRSF016020 15 291 7.2E-42 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 SmaCSM2_RS21530 742cf41e63005514fa7ce516f2e4cefc 296 Gene3D G3DSA:2.70.98.10 1 285 1.2E-54 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS21530 742cf41e63005514fa7ce516f2e4cefc 296 Pfam PF01263 Aldose 1-epimerase 20 281 4.8E-37 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SmaCSM2_RS11385 55f4aac698f504de2903b90089fc94c6 193 Pfam PF03358 NADPH-dependent FMN reductase 6 149 1.5E-29 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SmaCSM2_RS11385 55f4aac698f504de2903b90089fc94c6 193 Gene3D G3DSA:3.40.50.360 2 182 1.8E-34 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS11385 55f4aac698f504de2903b90089fc94c6 193 SUPERFAMILY SSF52218 1 181 1.51E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS11385 55f4aac698f504de2903b90089fc94c6 193 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 6 177 6.8E-78 T 28-03-2018 IPR019912 FMN reductase, MsuE-like KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 Gene3D G3DSA:3.40.190.10 25 123 1.2E-23 T 28-03-2018 SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 PIRSF PIRSF002854 1 264 9.2E-103 T 28-03-2018 IPR004872 Lipoprotein NlpA family SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 10 262 4.9E-72 T 28-03-2018 IPR004872 Lipoprotein NlpA family SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 Pfam PF03180 NLPA lipoprotein 29 264 3.4E-98 T 28-03-2018 IPR004872 Lipoprotein NlpA family SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 SUPERFAMILY SSF53850 28 264 1.35E-83 T 28-03-2018 SmaCSM2_RS18765 96784db5362e1e041e89ec8814ec1de3 264 Gene3D G3DSA:3.40.190.10 124 264 2.6E-56 T 28-03-2018 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 Pfam PF03486 HI0933-like protein 11 406 2.4E-99 T 28-03-2018 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 32 412 5.3E-166 T 28-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 12 405 5.2E-86 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 SUPERFAMILY SSF51905 9 198 2.65E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 SUPERFAMILY SSF51905 352 410 2.65E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 Gene3D G3DSA:3.50.50.60 10 408 1.1E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07940 fc77aeeadc6ca4c55c7cf974d0eeb78b 415 SUPERFAMILY SSF160996 204 306 1.1E-5 T 28-03-2018 SmaCSM2_RS21300 908d546717689b08f08bc1a170fd9da2 417 Pfam PF02321 Outer membrane efflux protein 245 407 1.8E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS21300 908d546717689b08f08bc1a170fd9da2 417 Pfam PF02321 Outer membrane efflux protein 56 212 8.0E-19 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS21300 908d546717689b08f08bc1a170fd9da2 417 Gene3D G3DSA:1.20.1600.10 23 411 3.3E-55 T 28-03-2018 SmaCSM2_RS21300 908d546717689b08f08bc1a170fd9da2 417 SUPERFAMILY SSF56954 9 410 1.1E-62 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 Pfam PF00593 TonB dependent receptor 473 1023 2.3E-40 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 175 4.2E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 Gene3D G3DSA:2.170.130.10 40 182 9.6E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 Gene3D G3DSA:2.40.170.20 188 1024 1.1E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 519 556 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 49 262 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 738 1024 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 302 350 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 615 676 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 SUPERFAMILY SSF56935 417 478 2.75E-82 T 28-03-2018 SmaCSM2_RS09625 1400920ea2689a0f256ad790bbd30ed4 1024 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 48 1024 2.4E-217 T 28-03-2018 IPR010104 Bacterial TonB-dependent receptor SmaCSM2_RS02845 d45828b2442f6ec30cdd22ec6017030e 419 Pfam PF06738 Putative threonine/serine exporter 21 263 8.6E-54 T 28-03-2018 IPR010619 Putative threonine/serine exporter SmaCSM2_RS02845 d45828b2442f6ec30cdd22ec6017030e 419 Pfam PF12821 Threonine/Serine exporter, ThrE 290 410 3.7E-14 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 Pfam PF00589 Phage integrase family 166 342 1.3E-10 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 Gene3D G3DSA:1.10.150.130 23 159 8.9E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 SUPERFAMILY SSF56349 162 344 2.68E-29 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 SUPERFAMILY SSF47823 108 157 9.02E-13 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 SUPERFAMILY SSF47823 31 79 9.02E-13 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal SmaCSM2_RS11040 c1075b63ec85e06896614f15fc2b5657 368 Gene3D G3DSA:1.10.443.10 164 353 2.0E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS16375 b04af9b291710d2b2368be106b08770f 305 SUPERFAMILY SSF53474 7 283 3.53E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16375 b04af9b291710d2b2368be106b08770f 305 Gene3D G3DSA:3.40.50.1820 7 284 1.5E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS16375 b04af9b291710d2b2368be106b08770f 305 Pfam PF12146 Serine aminopeptidase, S33 33 269 2.3E-19 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 Gene3D G3DSA:1.20.1050.60 551 645 1.4E-28 T 28-03-2018 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 Pfam PF07971 Glycosyl hydrolase family 92 423 957 1.7E-150 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 SUPERFAMILY SSF48208 529 942 4.08E-16 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 SUPERFAMILY SSF48208 453 500 4.08E-16 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 223 960 1.1E-135 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 Gene3D G3DSA:2.70.98.10 212 509 3.5E-72 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS17855 3c95816df3f27ea85ae1847ebbac347f 1114 Gene3D G3DSA:3.30.2080.10 803 969 9.1E-63 T 28-03-2018 SmaCSM2_RS09845 68dec1c9d6965796da9a83bbebc629c7 585 Pfam PF01368 DHH family 84 211 9.2E-9 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SmaCSM2_RS09845 68dec1c9d6965796da9a83bbebc629c7 585 Pfam PF02272 DHHA1 domain 330 463 9.8E-23 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SmaCSM2_RS09845 68dec1c9d6965796da9a83bbebc629c7 585 SUPERFAMILY SSF64182 58 476 3.79E-108 T 28-03-2018 SmaCSM2_RS09845 68dec1c9d6965796da9a83bbebc629c7 585 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 35 580 1.1E-136 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 SmaCSM2_RS09845 68dec1c9d6965796da9a83bbebc629c7 585 Gene3D G3DSA:3.90.1640.10 64 254 9.4E-19 T 28-03-2018 SmaCSM2_RS19265 6e93b90aa8422060c42c6f7684da9f1a 123 SUPERFAMILY SSF54593 3 121 6.31E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19265 6e93b90aa8422060c42c6f7684da9f1a 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 3.8E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS19265 6e93b90aa8422060c42c6f7684da9f1a 123 Gene3D G3DSA:3.10.180.10 1 121 1.5E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 Gene3D G3DSA:3.30.460.20 2 153 2.8E-33 T 28-03-2018 SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 Gene3D G3DSA:1.20.58.340 273 340 7.3E-16 T 28-03-2018 SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 SUPERFAMILY SSF144083 276 337 1.12E-15 T 28-03-2018 SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 Pfam PF01544 CorA-like Mg2+ transporter protein 49 336 3.7E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 Gene3D G3DSA:1.20.58.340 154 272 3.3E-29 T 28-03-2018 SmaCSM2_RS07065 932ee9639c5520b4285eba43e9cd5718 340 SUPERFAMILY SSF143865 6 272 1.96E-72 T 28-03-2018 SmaCSM2_RS03540 e9742f3f8ebc9f60768431e9ef66eeb1 215 Pfam PF06940 Domain of unknown function (DUF1287) 51 214 2.4E-65 T 28-03-2018 IPR009706 Protein of unknown function DUF1287 SmaCSM2_RS03540 e9742f3f8ebc9f60768431e9ef66eeb1 215 Gene3D G3DSA:3.90.1720.10 44 215 2.7E-6 T 28-03-2018 SmaCSM2_RS03540 e9742f3f8ebc9f60768431e9ef66eeb1 215 PIRSF PIRSF011444 13 215 3.1E-76 T 28-03-2018 IPR009706 Protein of unknown function DUF1287 SmaCSM2_RS03540 e9742f3f8ebc9f60768431e9ef66eeb1 215 ProDom PD357862 YIJF PERIPLASMIC ECS4873 PRECURSOR CC1379 SIGNAL DOMAIN PM0035 50 214 1.0E-57 T 28-03-2018 IPR009706 Protein of unknown function DUF1287 SmaCSM2_RS13465 60ef7fc573db8ea1e904907eaaf2d36a 412 SUPERFAMILY SSF51395 3 340 5.36E-99 T 28-03-2018 SmaCSM2_RS13465 60ef7fc573db8ea1e904907eaaf2d36a 412 Gene3D G3DSA:3.20.20.70 1 354 1.7E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS13465 60ef7fc573db8ea1e904907eaaf2d36a 412 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 339 3.2E-52 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS19205 f7b40041b25065eb5ea96de2f1c66568 309 Gene3D G3DSA:2.40.70.10 24 142 5.0E-10 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS19205 f7b40041b25065eb5ea96de2f1c66568 309 Gene3D G3DSA:2.40.70.10 174 294 4.7E-7 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS19205 f7b40041b25065eb5ea96de2f1c66568 309 Pfam PF13650 Aspartyl protease 38 132 1.4E-8 T 28-03-2018 SmaCSM2_RS19205 f7b40041b25065eb5ea96de2f1c66568 309 Pfam PF13650 Aspartyl protease 190 285 8.6E-7 T 28-03-2018 SmaCSM2_RS19205 f7b40041b25065eb5ea96de2f1c66568 309 SUPERFAMILY SSF50630 25 137 1.05E-5 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 269 277 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 Gene3D G3DSA:3.40.50.720 148 273 6.3E-36 T 28-03-2018 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 248 264 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 117 138 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 41 63 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 213 242 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 82 109 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 162 182 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 265 283 3.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 83 108 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 Hamap MF_01576 Bifunctional protein FolD [folD]. 10 292 37.135 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 SUPERFAMILY SSF53223 10 129 3.26E-37 T 28-03-2018 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 12 128 2.8E-35 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 SUPERFAMILY SSF51735 130 289 6.17E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 Gene3D G3DSA:3.40.50.10860 18 147 1.1E-44 T 28-03-2018 SmaCSM2_RS09085 0e32779d7c69bc9a32180ecad593ca1d 292 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 131 290 3.1E-63 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SmaCSM2_RS19825 91dfc3ba0e2b90f2568df96e6a499440 360 SUPERFAMILY SSF52518 9 353 1.84E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SmaCSM2_RS19825 91dfc3ba0e2b90f2568df96e6a499440 360 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 11 351 3.7E-128 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SmaCSM2_RS19825 91dfc3ba0e2b90f2568df96e6a499440 360 Pfam PF00676 Dehydrogenase E1 component 41 326 4.9E-70 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SmaCSM2_RS19825 91dfc3ba0e2b90f2568df96e6a499440 360 Gene3D G3DSA:3.40.50.970 2 352 7.8E-75 T 28-03-2018 SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 SUPERFAMILY SSF56300 172 229 1.25E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 SUPERFAMILY SSF56300 1 130 1.25E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 248 121.713 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 Pfam PF00149 Calcineurin-like phosphoesterase 1 206 5.5E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 Gene3D G3DSA:3.60.21.10 1 244 1.0E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS04295 85209f9256d731d5b263b3207e29b500 248 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 239 3.6E-105 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 SmaCSM2_RS09990 8aea28bffd0eca9b72b93a8593aa077d 198 Pfam PF03975 CheD chemotactic sensory transduction 65 165 2.9E-33 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 SmaCSM2_RS09990 8aea28bffd0eca9b72b93a8593aa077d 198 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 18 169 29.821 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 SmaCSM2_RS09990 8aea28bffd0eca9b72b93a8593aa077d 198 SUPERFAMILY SSF64438 24 169 1.28E-50 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic SmaCSM2_RS00460 63d3af8a6b5f2150eeae48676ac20f88 104 Gene3D G3DSA:3.30.10.10 42 102 4.3E-9 T 28-03-2018 SmaCSM2_RS00460 63d3af8a6b5f2150eeae48676ac20f88 104 Pfam PF11720 Peptidase inhibitor I78 family 43 104 1.7E-11 T 28-03-2018 IPR021719 Proteinase inhibitor I78 SmaCSM2_RS18780 85ebedf1ff81d15fda6575221008b47d 258 Pfam PF04338 Protein of unknown function, DUF481 39 257 1.1E-59 T 28-03-2018 IPR007433 Protein of unknown function DUF481 SmaCSM2_RS18780 85ebedf1ff81d15fda6575221008b47d 258 Gene3D G3DSA:2.40.160.20 8 258 0.0017 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 Gene3D G3DSA:2.40.170.20 181 985 8.3E-60 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 Pfam PF00593 TonB dependent receptor 365 979 8.5E-39 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 170 3.5E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 Gene3D G3DSA:2.170.130.10 29 177 1.5E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 SUPERFAMILY SSF56935 33 230 3.36E-90 T 28-03-2018 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 SUPERFAMILY SSF56935 674 718 3.36E-90 T 28-03-2018 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 SUPERFAMILY SSF56935 321 629 3.36E-90 T 28-03-2018 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 SUPERFAMILY SSF56935 766 863 3.36E-90 T 28-03-2018 SmaCSM2_RS09605 b937a192855520dba0f84e3a525fdb6a 985 SUPERFAMILY SSF56935 917 977 3.36E-90 T 28-03-2018 SmaCSM2_RS04350 683e11341e3eab9fcd3ae5625db12df9 334 Gene3D G3DSA:3.40.718.10 1 334 4.8E-136 T 28-03-2018 SmaCSM2_RS04350 683e11341e3eab9fcd3ae5625db12df9 334 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 327 1.8E-105 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS04350 683e11341e3eab9fcd3ae5625db12df9 334 SUPERFAMILY SSF53659 1 334 4.22E-126 T 28-03-2018 SmaCSM2_RS04350 683e11341e3eab9fcd3ae5625db12df9 334 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 226 245 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS04350 683e11341e3eab9fcd3ae5625db12df9 334 SMART SM01329 4 330 1.3E-179 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SmaCSM2_RS20975 45f409b2eda5e8c23757a29ec050bb69 318 Pfam PF00248 Aldo/keto reductase family 16 314 1.4E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS20975 45f409b2eda5e8c23757a29ec050bb69 318 SUPERFAMILY SSF51430 4 315 3.54E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS20975 45f409b2eda5e8c23757a29ec050bb69 318 Gene3D G3DSA:3.20.20.100 1 318 1.5E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS17720 7035995cf1df8b7480a5d91b4906145e 223 Gene3D G3DSA:1.10.287.70 110 223 3.3E-11 T 28-03-2018 SmaCSM2_RS17720 7035995cf1df8b7480a5d91b4906145e 223 SUPERFAMILY SSF81324 125 217 3.14E-10 T 28-03-2018 SmaCSM2_RS17720 7035995cf1df8b7480a5d91b4906145e 223 Pfam PF07885 Ion channel 135 215 1.1E-8 T 28-03-2018 IPR013099 Potassium channel domain SmaCSM2_RS12520 1f42d94708a96fc68a81b392633f9300 103 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 8 91 6.2E-21 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SmaCSM2_RS12520 1f42d94708a96fc68a81b392633f9300 103 Pfam PF12823 Domain of unknown function (DUF3817) 7 93 6.8E-21 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SmaCSM2_RS18770 00a0ab31500baddac91a907012c86e42 323 Pfam PF13280 WYL domain 145 315 5.6E-38 T 28-03-2018 IPR026881 WYL domain SmaCSM2_RS18770 00a0ab31500baddac91a907012c86e42 323 Gene3D G3DSA:1.10.10.10 1 65 4.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS18770 00a0ab31500baddac91a907012c86e42 323 Pfam PF08279 HTH domain 6 61 7.0E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SmaCSM2_RS18770 00a0ab31500baddac91a907012c86e42 323 SUPERFAMILY SSF46785 2 47 3.69E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21465 9b84100cf51dc073efc12d99c9f48a2c 75 Pfam PF02416 mttA/Hcf106 family 5 51 5.2E-15 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SmaCSM2_RS21465 9b84100cf51dc073efc12d99c9f48a2c 75 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 1.6E-22 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SmaCSM2_RS21465 9b84100cf51dc073efc12d99c9f48a2c 75 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 75 21.629 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 330 47.952 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 Pfam PF01409 tRNA synthetases class II core domain (F) 92 330 1.6E-102 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 SUPERFAMILY SSF55681 92 330 9.74E-78 T 28-03-2018 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 SUPERFAMILY SSF46589 12 99 2.56E-20 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 4.8E-22 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SmaCSM2_RS15015 c36afc862e07715a70a78058252c475f 331 Gene3D G3DSA:3.30.930.10 7 331 2.0E-83 T 28-03-2018 SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 SUPERFAMILY SSF47616 83 201 2.65E-26 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 SUPERFAMILY SSF52833 6 85 2.64E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 Gene3D G3DSA:3.40.30.10 2 98 5.8E-30 T 28-03-2018 SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 Pfam PF02798 Glutathione S-transferase, N-terminal domain 8 82 1.1E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 Gene3D G3DSA:1.20.1050.10 99 198 1.3E-22 T 28-03-2018 SmaCSM2_RS14185 8af730e32812edabd0923884cfb79f95 218 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 199 3.7E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 32 108 8.6E-8 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 122 226 2.4E-25 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 235 321 2.7E-24 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Gene3D G3DSA:1.10.287.460 112 212 1.3E-20 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Gene3D G3DSA:1.10.287.460 25 111 1.0E-8 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 Gene3D G3DSA:3.10.50.40 213 324 3.5E-38 T 28-03-2018 SmaCSM2_RS14055 50196492c4aae643e07d9edb9e8dbdf9 325 SUPERFAMILY SSF54534 141 323 7.66E-52 T 28-03-2018 SmaCSM2_RS03000 a05d97ed8a58cbc850b28eba54ad5061 241 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 77 192 1.4E-30 T 28-03-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b SmaCSM2_RS19705 0343d02fa10f3c41a6a09e056ed9949a 259 Pfam PF04402 Protein of unknown function (DUF541) 35 253 1.6E-28 T 28-03-2018 IPR007497 Protein of unknown function DUF541 SmaCSM2_RS20910 90e292f87f47be2ec74f0025906e2e3a 391 Gene3D G3DSA:2.70.50.50 26 208 3.3E-55 T 28-03-2018 SmaCSM2_RS20910 90e292f87f47be2ec74f0025906e2e3a 391 SUPERFAMILY SSF81296 26 208 2.52E-48 T 28-03-2018 IPR014756 Immunoglobulin E-set SmaCSM2_RS20910 90e292f87f47be2ec74f0025906e2e3a 391 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 26 205 9.1E-38 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SmaCSM2_RS14395 527cb7f724cdbb545c09a64a8a194a5d 446 Gene3D G3DSA:3.40.190.10 24 197 1.3E-42 T 28-03-2018 SmaCSM2_RS14395 527cb7f724cdbb545c09a64a8a194a5d 446 Gene3D G3DSA:3.40.190.10 198 374 5.2E-17 T 28-03-2018 SmaCSM2_RS14395 527cb7f724cdbb545c09a64a8a194a5d 446 Pfam PF13416 Bacterial extracellular solute-binding protein 48 361 1.3E-41 T 28-03-2018 SmaCSM2_RS14395 527cb7f724cdbb545c09a64a8a194a5d 446 SUPERFAMILY SSF53850 32 412 7.7E-86 T 28-03-2018 SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 Pfam PF00117 Glutamine amidotransferase class-I 6 195 5.5E-20 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 197 32.181 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 Gene3D G3DSA:3.40.50.880 1 200 2.0E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 PIRSF PIRSF000495 2 199 1.2E-60 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 196 6.5E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SmaCSM2_RS09555 adfb946b30f130db03ec1a5452d9aa32 200 SUPERFAMILY SSF52317 4 196 3.57E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS06275 ab8bd73c869a2cc5a9630277b1c3b783 405 SUPERFAMILY SSF103473 7 387 3.79E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS06275 ab8bd73c869a2cc5a9630277b1c3b783 405 Pfam PF07690 Major Facilitator Superfamily 15 273 8.0E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS06275 ab8bd73c869a2cc5a9630277b1c3b783 405 Gene3D G3DSA:1.20.1250.20 4 192 6.9E-22 T 28-03-2018 SmaCSM2_RS06275 ab8bd73c869a2cc5a9630277b1c3b783 405 Gene3D G3DSA:1.20.1250.20 200 388 7.7E-12 T 28-03-2018 SmaCSM2_RS05250 57304adec3185449f32920aabd3339dd 172 Pfam PF10029 Predicted periplasmic protein (DUF2271) 23 164 1.3E-52 T 28-03-2018 IPR014469 Protein of unknown function DUF2271 SmaCSM2_RS05250 57304adec3185449f32920aabd3339dd 172 PIRSF PIRSF014995 1 172 1.4E-71 T 28-03-2018 IPR014469 Protein of unknown function DUF2271 SmaCSM2_RS05510 3a271e4fb01ad5bbacd029071c374a48 405 Pfam PF03825 Nucleoside H+ symporter 6 394 2.4E-113 T 28-03-2018 SmaCSM2_RS05510 3a271e4fb01ad5bbacd029071c374a48 405 SUPERFAMILY SSF103473 7 396 3.01E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS05510 3a271e4fb01ad5bbacd029071c374a48 405 Gene3D G3DSA:1.20.1250.20 2 193 4.2E-13 T 28-03-2018 SmaCSM2_RS05510 3a271e4fb01ad5bbacd029071c374a48 405 Gene3D G3DSA:1.20.1250.20 200 403 3.9E-23 T 28-03-2018 SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 Pfam PF01545 Cation efflux family 20 209 7.2E-46 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 Gene3D G3DSA:3.30.70.1350 213 290 6.7E-12 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 SUPERFAMILY SSF160240 216 286 1.29E-8 T 28-03-2018 SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 SUPERFAMILY SSF161111 15 210 1.83E-57 T 28-03-2018 SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 Gene3D G3DSA:1.20.1510.10 13 209 9.8E-60 T 28-03-2018 SmaCSM2_RS06290 6c050c5e6c988fed23c73cbe69b1cdc7 326 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 289 1.3E-85 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SmaCSM2_RS07175 f7351487a7744bfb8743a44e71f46098 89 Pfam PF03966 Trm112p-like protein 2 68 7.6E-6 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 SmaCSM2_RS07175 f7351487a7744bfb8743a44e71f46098 89 Gene3D G3DSA:2.20.25.10 8 88 4.6E-10 T 28-03-2018 SmaCSM2_RS07175 f7351487a7744bfb8743a44e71f46098 89 SUPERFAMILY SSF158997 52 80 1.44E-7 T 28-03-2018 SmaCSM2_RS07175 f7351487a7744bfb8743a44e71f46098 89 SUPERFAMILY SSF158997 1 24 1.44E-7 T 28-03-2018 SmaCSM2_RS16290 996143b3980b6e538e427ac0fa109811 90 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 72 1.4E-9 T 28-03-2018 IPR008554 Glutaredoxin-like SmaCSM2_RS16290 996143b3980b6e538e427ac0fa109811 90 SUPERFAMILY SSF52833 1 74 2.35E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS16290 996143b3980b6e538e427ac0fa109811 90 Gene3D G3DSA:3.40.30.10 1 74 1.3E-8 T 28-03-2018 SmaCSM2_RS06230 f165b37928c3b6d4ac5fc02b4d1bb6ee 238 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 173 3.5E-21 T 28-03-2018 SmaCSM2_RS06230 f165b37928c3b6d4ac5fc02b4d1bb6ee 238 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 181 5.5E-29 T 28-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 SmaCSM2_RS06230 f165b37928c3b6d4ac5fc02b4d1bb6ee 238 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 170 1.4E-14 T 28-03-2018 SmaCSM2_RS06230 f165b37928c3b6d4ac5fc02b4d1bb6ee 238 SUPERFAMILY SSF56784 3 210 8.81E-40 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS06230 f165b37928c3b6d4ac5fc02b4d1bb6ee 238 Gene3D G3DSA:3.40.50.1000 2 180 7.7E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS10665 36518d0f25937b75e2ac3511d9dc6fc3 77 Gene3D G3DSA:1.20.5.440 1 27 0.29 T 28-03-2018 SmaCSM2_RS10665 36518d0f25937b75e2ac3511d9dc6fc3 77 Gene3D G3DSA:1.20.5.440 38 76 0.21 T 28-03-2018 SmaCSM2_RS10665 36518d0f25937b75e2ac3511d9dc6fc3 77 SUPERFAMILY SSF57987 33 77 2.17E-17 T 28-03-2018 SmaCSM2_RS10665 36518d0f25937b75e2ac3511d9dc6fc3 77 Pfam PF10389 Bacteriophage coat protein B 36 77 4.3E-19 T 28-03-2018 IPR008020 Capsid protein G8P GO:0019028 SmaCSM2_RS13330 f01299af48888349c09b7ec355b15299 255 Pfam PF02525 Flavodoxin-like fold 1 202 2.3E-42 T 28-03-2018 IPR003680 Flavodoxin-like fold SmaCSM2_RS13330 f01299af48888349c09b7ec355b15299 255 SUPERFAMILY SSF52218 1 224 9.64E-54 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS13330 f01299af48888349c09b7ec355b15299 255 Gene3D G3DSA:3.40.50.360 1 248 4.8E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS12370 3bda413348a6ef592b33a3aa54432eef 313 Pfam PF13650 Aspartyl protease 68 158 2.4E-9 T 28-03-2018 SmaCSM2_RS12370 3bda413348a6ef592b33a3aa54432eef 313 Gene3D G3DSA:2.40.70.10 61 184 3.6E-9 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS12370 3bda413348a6ef592b33a3aa54432eef 313 Gene3D G3DSA:2.40.70.10 192 305 2.3E-7 T 28-03-2018 IPR021109 Aspartic peptidase domain SmaCSM2_RS10540 5e59d30cf64a63d1f07dc0ee65bed060 357 SUPERFAMILY SSF53335 79 349 5.37E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS10540 5e59d30cf64a63d1f07dc0ee65bed060 357 Pfam PF02353 Mycolic acid cyclopropane synthetase 77 340 5.7E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS10540 5e59d30cf64a63d1f07dc0ee65bed060 357 Gene3D G3DSA:3.40.50.150 72 352 4.4E-44 T 28-03-2018 SmaCSM2_RS09150 0206eefbda83bc986095dba98e401b41 1053 Pfam PF06414 Zeta toxin 15 201 1.9E-46 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 SmaCSM2_RS09150 0206eefbda83bc986095dba98e401b41 1053 Gene3D G3DSA:3.40.50.300 12 243 1.2E-20 T 28-03-2018 SmaCSM2_RS09150 0206eefbda83bc986095dba98e401b41 1053 SUPERFAMILY SSF52540 19 171 4.4E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21445 4180f3da2c3e11c77e82fdbc13c40f96 248 Pfam PF00117 Glutamine amidotransferase class-I 56 193 1.9E-19 T 28-03-2018 IPR017926 Glutamine amidotransferase SmaCSM2_RS21445 4180f3da2c3e11c77e82fdbc13c40f96 248 SUPERFAMILY SSF52317 28 207 4.44E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS21445 4180f3da2c3e11c77e82fdbc13c40f96 248 Gene3D G3DSA:3.40.50.880 14 238 4.7E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 Hamap MF_00023 SsrA-binding protein [smpB]. 1 166 67.808 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 19 141 1.0E-55 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 Pfam PF01668 SmpB protein 19 161 1.6E-56 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 ProSitePatterns PS01317 SsrA-binding protein. 37 49 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 SUPERFAMILY SSF74982 14 143 1.31E-49 T 28-03-2018 IPR023620 Small protein B SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 TIGRFAM TIGR00086 smpB: SsrA-binding protein 19 160 2.0E-52 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SmaCSM2_RS08700 721be08631b3e61690f37380ad1a8bd0 167 Gene3D G3DSA:2.40.280.10 19 138 2.0E-46 T 28-03-2018 IPR023620 Small protein B SmaCSM2_RS21525 b7bd3a39db0e10e0c706452502aed9ba 256 Pfam PF14237 Domain of unknown function (DUF4339) 6 49 1.0E-14 T 28-03-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 SmaCSM2_RS21525 b7bd3a39db0e10e0c706452502aed9ba 256 Pfam PF10947 Protein of unknown function (DUF2628) 134 205 3.2E-14 T 28-03-2018 IPR024399 Protein of unknown function DUF2628 SmaCSM2_RS14650 34b740bb1b37782af079b0597baa1c50 415 Gene3D G3DSA:1.20.1250.20 223 412 4.0E-12 T 28-03-2018 SmaCSM2_RS14650 34b740bb1b37782af079b0597baa1c50 415 Pfam PF05977 Transmembrane secretion effector 12 400 6.3E-32 T 28-03-2018 IPR010290 Transmembrane secretion effector SmaCSM2_RS14650 34b740bb1b37782af079b0597baa1c50 415 Gene3D G3DSA:1.20.1250.20 12 210 5.4E-19 T 28-03-2018 SmaCSM2_RS14650 34b740bb1b37782af079b0597baa1c50 415 SUPERFAMILY SSF103473 20 413 5.36E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS18055 3963a2022a9fe4c2dd13f99676379f3e 367 Gene3D G3DSA:3.20.20.70 4 367 5.4E-116 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS18055 3963a2022a9fe4c2dd13f99676379f3e 367 SUPERFAMILY SSF51395 3 366 2.25E-110 T 28-03-2018 SmaCSM2_RS18055 3963a2022a9fe4c2dd13f99676379f3e 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 343 1.1E-80 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS01565 36ba6eac1c0415e049e31fb96530dcc2 232 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 23 218 5.1E-28 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 SmaCSM2_RS01565 36ba6eac1c0415e049e31fb96530dcc2 232 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 11 211 4.5E-32 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 SmaCSM2_RS01565 36ba6eac1c0415e049e31fb96530dcc2 232 Gene3D G3DSA:2.40.160.10 67 232 0.0029 T 28-03-2018 SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 Gene3D G3DSA:3.30.360.10 135 347 1.9E-39 T 28-03-2018 SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 SUPERFAMILY SSF51735 4 157 6.25E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 120 8.6E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 SUPERFAMILY SSF55347 130 284 4.58E-23 T 28-03-2018 SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 Gene3D G3DSA:3.40.50.720 2 134 1.3E-34 T 28-03-2018 SmaCSM2_RS18295 f53413d59cd5cae4595af97bc0a3a096 347 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 199 6.1E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 Gene3D G3DSA:3.40.50.2300 1 119 1.7E-32 T 28-03-2018 SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.3E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 SUPERFAMILY SSF52172 1 176 4.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 SMART SM00448 1 112 1.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 Gene3D G3DSA:1.10.10.10 120 225 3.2E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 SMART SM00862 145 218 1.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SmaCSM2_RS17900 8a67d798a81724b58ee175b37477c4f6 229 Pfam PF00072 Response regulator receiver domain 4 111 2.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 Gene3D G3DSA:2.70.70.10 126 261 2.9E-34 T 28-03-2018 SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 Gene3D G3DSA:3.10.350.10 42 125 1.8E-16 T 28-03-2018 SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 SMART SM00257 55 99 2.6E-9 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 Pfam PF01551 Peptidase family M23 161 254 7.0E-28 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 Pfam PF01476 LysM domain 57 97 4.6E-12 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS08075 99e7d10465c57a73644a48aac8204fa7 261 SUPERFAMILY SSF51261 56 258 1.73E-44 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS05025 85f117851fdbe7318d4ab3f199e9569c 595 Pfam PF13687 Domain of unknown function (DUF4153) 154 390 3.9E-21 T 28-03-2018 IPR025291 Protein of unknown function DUF4153 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 14 231 6.5E-64 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 11 235 31.299 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 230 1.6E-38 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 SUPERFAMILY SSF51366 12 234 1.67E-55 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 SMART SM00934 13 230 6.0E-70 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 66 79 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SmaCSM2_RS00355 cdb59971ce3f8ed02fb008529fa5933d 241 Gene3D G3DSA:3.20.20.70 9 235 2.9E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS16345 b36821d8e7f1578fafb78d8afc85d0d8 339 Gene3D G3DSA:3.90.550.10 2 210 3.9E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS16345 b36821d8e7f1578fafb78d8afc85d0d8 339 Pfam PF00535 Glycosyl transferase family 2 8 164 1.3E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS16345 b36821d8e7f1578fafb78d8afc85d0d8 339 SUPERFAMILY SSF53448 7 260 2.97E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS17965 d7d1caec380936e81e53afa4fc882f11 258 Gene3D G3DSA:3.40.50.1580 1 248 9.3E-43 T 28-03-2018 SmaCSM2_RS17965 d7d1caec380936e81e53afa4fc882f11 258 Pfam PF01048 Phosphorylase superfamily 62 224 1.6E-24 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SmaCSM2_RS17965 d7d1caec380936e81e53afa4fc882f11 258 SUPERFAMILY SSF53167 4 253 4.71E-63 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SmaCSM2_RS17965 d7d1caec380936e81e53afa4fc882f11 258 TIGRFAM TIGR01721 AMN-like: putative AMP nucleosidase 2 256 8.0E-100 T 28-03-2018 IPR010944 AMP nucleosidase, putative SmaCSM2_RS00155 d87b8a78c6393d7bb0eb563f19c30b4b 411 Gene3D G3DSA:2.40.50.100 240 380 0.14 T 28-03-2018 SmaCSM2_RS00155 d87b8a78c6393d7bb0eb563f19c30b4b 411 SUPERFAMILY SSF51230 180 249 3.26E-9 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS00155 d87b8a78c6393d7bb0eb563f19c30b4b 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 167 219 5.2E-8 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS00155 d87b8a78c6393d7bb0eb563f19c30b4b 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 221 325 1.4E-17 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS00155 d87b8a78c6393d7bb0eb563f19c30b4b 411 Gene3D G3DSA:2.40.50.100 184 239 2.3E-14 T 28-03-2018 SmaCSM2_RS12445 9880977085a839c79d3e3792af921576 306 SUPERFAMILY SSF53187 35 265 3.04E-36 T 28-03-2018 SmaCSM2_RS12445 9880977085a839c79d3e3792af921576 306 Gene3D G3DSA:3.40.630.10 17 304 3.9E-29 T 28-03-2018 SmaCSM2_RS12445 9880977085a839c79d3e3792af921576 306 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 78 178 8.2E-9 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 SmaCSM2_RS09670 aec402617c09cff2e6dbb3850d5e28bb 185 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 38.885 T 28-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 SmaCSM2_RS09670 aec402617c09cff2e6dbb3850d5e28bb 185 Pfam PF03079 ARD/ARD' family 3 164 2.8E-33 T 28-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 SmaCSM2_RS09670 aec402617c09cff2e6dbb3850d5e28bb 185 SUPERFAMILY SSF51182 3 179 7.59E-42 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS09670 aec402617c09cff2e6dbb3850d5e28bb 185 Gene3D G3DSA:2.60.120.10 2 157 3.2E-41 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS01290 49600fbe6b43257c5785d32b8239a03c 484 Pfam PF00916 Sulfate permease family 162 347 5.6E-29 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SmaCSM2_RS01290 49600fbe6b43257c5785d32b8239a03c 484 Pfam PF00916 Sulfate permease family 16 143 7.8E-25 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SmaCSM2_RS01290 49600fbe6b43257c5785d32b8239a03c 484 Gene3D G3DSA:3.30.750.24 388 479 1.9E-12 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS01290 49600fbe6b43257c5785d32b8239a03c 484 SUPERFAMILY SSF52091 388 478 2.16E-11 T 28-03-2018 IPR002645 STAS domain SmaCSM2_RS12405 d51acf492cb434b3d8b470aa69075212 115 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 57 110 7.0E-7 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS12405 d51acf492cb434b3d8b470aa69075212 115 Pfam PF11776 Nickel/cobalt transporter regulator 60 111 6.9E-19 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB SmaCSM2_RS12405 d51acf492cb434b3d8b470aa69075212 115 Gene3D G3DSA:3.10.450.160 23 115 5.8E-19 T 28-03-2018 SmaCSM2_RS12065 b3559ed78f55bf978e5dea14a3c6cb43 226 Pfam PF00857 Isochorismatase family 19 172 5.9E-19 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12065 b3559ed78f55bf978e5dea14a3c6cb43 226 SUPERFAMILY SSF52499 12 210 1.1E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12065 b3559ed78f55bf978e5dea14a3c6cb43 226 Gene3D G3DSA:3.40.50.850 9 215 7.5E-39 T 28-03-2018 SmaCSM2_RS04280 82566aed3bd472274a0e00768d0cc0fd 274 Pfam PF04305 Protein of unknown function (DUF455) 21 266 4.7E-98 T 28-03-2018 IPR007402 Protein of unknown function DUF455 SmaCSM2_RS04280 82566aed3bd472274a0e00768d0cc0fd 274 Gene3D G3DSA:1.20.1260.10 80 242 1.5E-45 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS04280 82566aed3bd472274a0e00768d0cc0fd 274 PIRSF PIRSF012318 6 274 6.8E-104 T 28-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 SmaCSM2_RS04280 82566aed3bd472274a0e00768d0cc0fd 274 SUPERFAMILY SSF47240 83 254 4.79E-21 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS18640 c90b4dae0bc4affc7e59b31c7496b91b 425 Gene3D G3DSA:1.20.1600.10 19 348 1.4E-16 T 28-03-2018 SmaCSM2_RS18640 c90b4dae0bc4affc7e59b31c7496b91b 425 Pfam PF13533 Biotin-lipoyl like 96 132 2.0E-7 T 28-03-2018 SmaCSM2_RS18640 c90b4dae0bc4affc7e59b31c7496b91b 425 Pfam PF13437 HlyD family secretion protein 244 340 1.3E-12 T 28-03-2018 SmaCSM2_RS18640 c90b4dae0bc4affc7e59b31c7496b91b 425 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 213 424 1.1E-30 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS07305 cddaaed4e7f310073094695ae3b14400 220 Pfam PF01618 MotA/TolQ/ExbB proton channel family 66 188 1.3E-32 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS05315 bfc3d354a5588c06bf78a54a5a6f48f9 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 243 4.2E-109 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SmaCSM2_RS05315 bfc3d354a5588c06bf78a54a5a6f48f9 254 SMART SM00382 26 230 5.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS05315 bfc3d354a5588c06bf78a54a5a6f48f9 254 SUPERFAMILY SSF52540 2 231 7.03E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS05315 bfc3d354a5588c06bf78a54a5a6f48f9 254 Gene3D G3DSA:3.40.50.300 1 248 3.3E-44 T 28-03-2018 SmaCSM2_RS05315 bfc3d354a5588c06bf78a54a5a6f48f9 254 Pfam PF00005 ABC transporter 17 172 6.0E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS01205 5b4abe906566abe3d5b41245c4c050ba 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 5.3E-55 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 SmaCSM2_RS01205 5b4abe906566abe3d5b41245c4c050ba 141 Gene3D G3DSA:3.30.300.20 48 141 4.6E-23 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SmaCSM2_RS01205 5b4abe906566abe3d5b41245c4c050ba 141 SUPERFAMILY SSF82784 1 139 3.01E-45 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS01205 5b4abe906566abe3d5b41245c4c050ba 141 Pfam PF02566 OsmC-like protein 44 138 2.1E-17 T 28-03-2018 IPR003718 OsmC/Ohr family SmaCSM2_RS01205 5b4abe906566abe3d5b41245c4c050ba 141 Gene3D G3DSA:2.20.25.10 4 47 1.6E-19 T 28-03-2018 SmaCSM2_RS02690 df34803a1f6b49ab8c1e1157f59efb34 384 Gene3D G3DSA:3.90.550.10 2 289 9.6E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02690 df34803a1f6b49ab8c1e1157f59efb34 384 SUPERFAMILY SSF53448 9 232 4.39E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02690 df34803a1f6b49ab8c1e1157f59efb34 384 Pfam PF00535 Glycosyl transferase family 2 9 130 3.4E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 44 521 1.8E-196 T 28-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 Gene3D G3DSA:2.70.98.10 44 411 7.8E-163 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 Hamap MF_01068 Glucans biosynthesis protein D [mdoD]. 1 533 59.756 T 28-03-2018 IPR023724 Glucan biosynthesis, MdoD SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 Gene3D G3DSA:2.60.40.10 415 525 1.1E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 SUPERFAMILY SSF74650 44 414 1.98E-155 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 PIRSF PIRSF006281 1 525 3.9E-207 T 28-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D SmaCSM2_RS00315 e75654e00ff19b1a40500ca3fb0dcf94 534 SUPERFAMILY SSF81296 414 524 9.8E-28 T 28-03-2018 IPR014756 Immunoglobulin E-set SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 10 340 1.1E-98 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 SUPERFAMILY SSF55781 77 343 8.44E-60 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 Gene3D G3DSA:3.30.450.40 189 348 3.3E-41 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 Gene3D G3DSA:1.10.10.10 2 90 3.5E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 7 335 27.624 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 8 79 6.7E-6 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 SUPERFAMILY SSF46785 8 88 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 Pfam PF01628 HrcA protein C terminal domain 110 328 1.9E-56 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SmaCSM2_RS08740 253217085b15d50bec9d9629ffbc87cd 354 PIRSF PIRSF005485 5 345 2.3E-108 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SmaCSM2_RS00615 1658f0533daac4c6dd0a2caa42523700 264 Pfam PF02673 Bacitracin resistance protein BacA 7 254 8.2E-68 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SmaCSM2_RS00615 1658f0533daac4c6dd0a2caa42523700 264 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 260 15.911 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SmaCSM2_RS06035 168b91f784902c2342d54c20004f3501 768 Gene3D G3DSA:1.25.40.10 71 298 1.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS06035 168b91f784902c2342d54c20004f3501 768 Gene3D G3DSA:1.25.40.10 383 760 1.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS06035 168b91f784902c2342d54c20004f3501 768 Pfam PF14559 Tetratricopeptide repeat 490 538 1.9E-5 T 28-03-2018 SmaCSM2_RS06035 168b91f784902c2342d54c20004f3501 768 SUPERFAMILY SSF48452 234 285 1.66E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS06035 168b91f784902c2342d54c20004f3501 768 SUPERFAMILY SSF48452 486 545 1.66E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 3.7E-23 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 3.7E-23 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 3.7E-23 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 Pfam PF02416 mttA/Hcf106 family 4 42 4.4E-7 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 151 18.417 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 SmaCSM2_RS21460 84af3202c6bd9dd1f61ab3ddff6e9c62 152 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 2.8E-30 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 69 762 1.2E-75 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 165 2.5E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 Gene3D G3DSA:2.170.130.10 37 173 1.4E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 SUPERFAMILY SSF56935 38 762 4.19E-132 T 28-03-2018 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 Pfam PF00593 TonB dependent receptor 257 761 2.4E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 745 762 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS05280 6995631e07feb70a0ebd2e2cd94528e4 762 Gene3D G3DSA:2.40.170.20 179 762 1.7E-89 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16865 1260b10ced83f642ade2b36d63430766 145 Pfam PF04134 Protein of unknown function, DUF393 19 128 4.4E-33 T 28-03-2018 IPR007263 Protein of unknown function DUF393 SmaCSM2_RS10550 0c33bfadae17b969c40bfc859ff86e58 181 Pfam PF11086 Protein of unknown function (DUF2878) 5 159 1.1E-36 T 28-03-2018 IPR021306 Protein of unknown function DUF2878 SmaCSM2_RS11810 da4723564cfbd44d337622e08271bb62 285 PIRSF PIRSF018266 15 284 7.4E-65 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS11810 da4723564cfbd44d337622e08271bb62 285 Pfam PF16344 Domain of unknown function (DUF4974) 182 263 3.9E-8 T 28-03-2018 IPR032508 Protein FecR, C-terminal SmaCSM2_RS11810 da4723564cfbd44d337622e08271bb62 285 Pfam PF04773 FecR protein 78 169 1.5E-17 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS00055 2b47f054b692c91f67c2c39d48ed7305 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 135 1.9E-25 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS21570 b0b14fcc171ff818474dd0c665d787bf 233 Pfam PF13835 Domain of unknown function (DUF4194) 56 214 3.0E-43 T 28-03-2018 IPR025449 Protein of unknown function DUF4194 SmaCSM2_RS02675 d227da566e839dc60976cd53d62ec371 358 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 275 1.8E-37 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS02675 d227da566e839dc60976cd53d62ec371 358 Gene3D G3DSA:3.40.50.720 1 230 5.3E-27 T 28-03-2018 SmaCSM2_RS02675 d227da566e839dc60976cd53d62ec371 358 SUPERFAMILY SSF51735 2 132 3.82E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02675 d227da566e839dc60976cd53d62ec371 358 SUPERFAMILY SSF51735 169 356 3.82E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02675 d227da566e839dc60976cd53d62ec371 358 Gene3D G3DSA:3.90.25.10 231 357 2.7E-24 T 28-03-2018 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 Pfam PF00593 TonB dependent receptor 297 747 2.0E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 53 749 4.2E-72 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 732 749 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 Gene3D G3DSA:2.170.130.10 27 177 1.4E-35 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 SUPERFAMILY SSF56935 35 749 7.33E-127 T 28-03-2018 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 Gene3D G3DSA:2.40.170.20 178 749 7.6E-84 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS06285 9557e3a1aab0c9184058e313fe61adf3 749 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 166 3.1E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS04480 4ea3516bcef4120de8ca3b6e23a4b7b4 214 Gene3D G3DSA:3.40.50.150 62 194 5.5E-11 T 28-03-2018 SmaCSM2_RS04480 4ea3516bcef4120de8ca3b6e23a4b7b4 214 SUPERFAMILY SSF53335 80 175 1.04E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS04480 4ea3516bcef4120de8ca3b6e23a4b7b4 214 Pfam PF08241 Methyltransferase domain 83 121 1.6E-4 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS19160 c63ee568dc84964bed88078b05fa2dac 143 Gene3D G3DSA:3.10.450.50 13 142 2.0E-7 T 28-03-2018 SmaCSM2_RS19160 c63ee568dc84964bed88078b05fa2dac 143 SUPERFAMILY SSF54427 22 139 9.35E-23 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS19160 c63ee568dc84964bed88078b05fa2dac 143 Pfam PF12893 Putative lumazine-binding 22 137 2.2E-26 T 28-03-2018 SmaCSM2_RS03275 0505406b89872f9f8ac50c58a1895e84 249 Pfam PF08478 POTRA domain, FtsQ-type 35 103 1.3E-18 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type SmaCSM2_RS03275 0505406b89872f9f8ac50c58a1895e84 249 Pfam PF03799 Cell division protein FtsQ 107 219 7.6E-23 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB SmaCSM2_RS03275 0505406b89872f9f8ac50c58a1895e84 249 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 4 227 23.541 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 SmaCSM2_RS11920 eb15e50831fcd93342faf50cf4056e30 294 Pfam PF05425 Copper resistance protein D 183 287 1.9E-19 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 SmaCSM2_RS08070 0ef13436084eaf81097411344e4ef108 204 Pfam PF09335 SNARE associated Golgi protein 55 164 6.8E-8 T 28-03-2018 IPR032816 SNARE associated Golgi protein SmaCSM2_RS19390 476d18010f28ebdf3cd7755db0e24842 205 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 96 9.8E-11 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 9 193 2.0E-69 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 Gene3D G3DSA:3.40.50.300 76 191 3.7E-12 T 28-03-2018 SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 SUPERFAMILY SSF52540 9 195 4.5E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 Gene3D G3DSA:3.40.50.300 5 75 1.0E-11 T 28-03-2018 SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 Pfam PF01926 50S ribosome-binding GTPase 27 139 2.2E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SmaCSM2_RS18105 29f0dd773329b468a561e2eddf6ef578 200 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 197 26.641 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 SmaCSM2_RS07595 bc9919e8d7771b9d9e01e525a96e5383 132 Gene3D G3DSA:1.20.1070.10 11 104 2.4E-4 T 28-03-2018 SmaCSM2_RS07595 bc9919e8d7771b9d9e01e525a96e5383 132 Pfam PF11990 Protein of unknown function (DUF3487) 12 130 1.0E-41 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 SmaCSM2_RS07595 bc9919e8d7771b9d9e01e525a96e5383 132 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 14 129 1.7E-42 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 Gene3D G3DSA:2.170.130.10 29 172 3.3E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 Gene3D G3DSA:2.40.170.20 175 948 5.4E-77 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 165 4.3E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 SUPERFAMILY SSF56935 303 438 3.66E-103 T 28-03-2018 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 SUPERFAMILY SSF56935 36 230 3.66E-103 T 28-03-2018 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 SUPERFAMILY SSF56935 488 637 3.66E-103 T 28-03-2018 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 SUPERFAMILY SSF56935 677 948 3.66E-103 T 28-03-2018 SmaCSM2_RS17705 cde7a64fd7a149e700c05436b0a3e774 948 Pfam PF00593 TonB dependent receptor 487 945 7.8E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS15545 5630f5cd918f233457d5534956cad6fd 123 Pfam PF09685 Domain of unknown function (DUF4870) 20 122 4.6E-34 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 SmaCSM2_RS07200 3bafb2fc23d06a72feaecaee5a36ee9c 106 Pfam PF00462 Glutaredoxin 17 81 1.7E-16 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SmaCSM2_RS07200 3bafb2fc23d06a72feaecaee5a36ee9c 106 SUPERFAMILY SSF52833 3 103 9.4E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS07200 3bafb2fc23d06a72feaecaee5a36ee9c 106 Gene3D G3DSA:3.40.30.10 1 106 3.8E-26 T 28-03-2018 SmaCSM2_RS07200 3bafb2fc23d06a72feaecaee5a36ee9c 106 PIRSF PIRSF005894 1 106 2.0E-44 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 SmaCSM2_RS07200 3bafb2fc23d06a72feaecaee5a36ee9c 106 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 101 2.2E-40 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 Pfam PF00561 alpha/beta hydrolase fold 98 462 8.2E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 130 141 2.5E-6 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 99 107 2.5E-6 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 210 224 2.5E-6 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 Gene3D G3DSA:3.40.50.1820 50 485 6.7E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 SUPERFAMILY SSF53474 80 147 5.45E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 SUPERFAMILY SSF53474 321 464 5.45E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20890 4544363991a325c7e8f598fe1b6b9784 508 SUPERFAMILY SSF53474 186 240 5.45E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS12855 48e3948171dcad7403667cc623c76786 145 Pfam PF12713 Domain of unknown function (DUF3806) 47 129 8.4E-24 T 28-03-2018 IPR024266 Domain of unknown function DUF3806 SmaCSM2_RS16175 1f771557c375d7633056baa5ab78b109 486 Gene3D G3DSA:1.10.4100.10 397 484 3.3E-12 T 28-03-2018 SmaCSM2_RS16175 1f771557c375d7633056baa5ab78b109 486 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 15 484 4.5E-239 T 28-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 SmaCSM2_RS16175 1f771557c375d7633056baa5ab78b109 486 Pfam PF03972 MmgE/PrpD family 20 466 4.7E-154 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 SmaCSM2_RS16175 1f771557c375d7633056baa5ab78b109 486 Gene3D G3DSA:1.10.4100.10 1 333 1.9E-97 T 28-03-2018 SmaCSM2_RS16175 1f771557c375d7633056baa5ab78b109 486 SUPERFAMILY SSF103378 15 483 5.49E-149 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 Gene3D G3DSA:3.40.190.10 85 199 5.7E-15 T 28-03-2018 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 SUPERFAMILY SSF53850 89 287 1.38E-22 T 28-03-2018 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 Pfam PF03466 LysR substrate binding domain 87 285 4.4E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 Gene3D G3DSA:1.10.10.10 1 84 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 3.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS10990 473cbd0f779a43ed581a3cbfa853a3fd 302 SUPERFAMILY SSF46785 3 86 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS07570 7fd13aaa4625cdd79b0b9216ec86fca0 955 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 51 946 0.0 T 28-03-2018 IPR022303 Conjugative transfer ATPase SmaCSM2_RS07570 7fd13aaa4625cdd79b0b9216ec86fca0 955 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 63 335 4.5E-72 T 28-03-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase SmaCSM2_RS07570 7fd13aaa4625cdd79b0b9216ec86fca0 955 SUPERFAMILY SSF52540 481 606 4.45E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07570 7fd13aaa4625cdd79b0b9216ec86fca0 955 SUPERFAMILY SSF52540 642 874 4.45E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS07570 7fd13aaa4625cdd79b0b9216ec86fca0 955 Gene3D G3DSA:3.40.50.300 525 892 2.2E-16 T 28-03-2018 SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 SUPERFAMILY SSF51735 400 531 9.85E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 Gene3D G3DSA:3.40.50.720 393 515 3.1E-20 T 28-03-2018 SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 Pfam PF00999 Sodium/hydrogen exchanger family 10 371 3.2E-62 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 Gene3D G3DSA:1.20.91.10 227 307 3.5E-14 T 28-03-2018 SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 Pfam PF02254 TrkA-N domain 403 511 5.6E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SmaCSM2_RS21040 b10a7d96e714f3381bf46180e700c87d 592 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 282 8.0E-78 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 40 7.2E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 20 145 2.4E-27 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 Pfam PF08334 Type II secretion system (T2SS), protein G 43 144 2.3E-28 T 28-03-2018 IPR013545 Type II secretion system protein G SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 40 3.6E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 SUPERFAMILY SSF54523 48 144 8.89E-23 T 28-03-2018 SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 56 74 3.9E-11 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 20 45 3.9E-11 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SmaCSM2_RS02970 e0153aace265ce1e7935c66f36fffb9f 147 Gene3D G3DSA:3.30.700.10 32 144 7.1E-14 T 28-03-2018 SmaCSM2_RS19270 88fb27910f73a582fa0248eea3b7cce4 238 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 16 204 4.1E-20 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS19270 88fb27910f73a582fa0248eea3b7cce4 238 Gene3D G3DSA:3.40.190.10 9 110 8.8E-10 T 28-03-2018 SmaCSM2_RS19270 88fb27910f73a582fa0248eea3b7cce4 238 SMART SM00062 15 230 1.3E-15 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SmaCSM2_RS19270 88fb27910f73a582fa0248eea3b7cce4 238 SUPERFAMILY SSF53850 16 211 1.0E-27 T 28-03-2018 SmaCSM2_RS19270 88fb27910f73a582fa0248eea3b7cce4 238 Gene3D G3DSA:3.40.190.10 111 192 5.4E-15 T 28-03-2018 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 SMART SM00448 13 124 4.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 204 4.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 SUPERFAMILY SSF46894 139 208 1.43E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 Pfam PF00072 Response regulator receiver domain 15 124 4.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 Gene3D G3DSA:3.40.50.2300 5 140 5.7E-28 T 28-03-2018 SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 Gene3D G3DSA:1.10.10.10 141 210 3.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 SUPERFAMILY SSF52172 15 152 1.85E-31 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS11765 bd28a30aa4a522f61c67a3d216f64f62 213 SMART SM00421 148 205 1.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10865 eff03fc97b13e661ddff250679301016 121 Pfam PF04214 Protein of unknown function, DUF 26 94 2.9E-32 T 28-03-2018 IPR007332 Protein of unknown function DUF411 SmaCSM2_RS13405 8a84d96970678e7c4f1ea3824d2adb92 102 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 3 79 1.5E-21 T 28-03-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 80 91 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Gene3D G3DSA:3.30.1490.20 116 182 2.8E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Pfam PF01820 D-ala D-ala ligase N-terminus 19 103 1.3E-13 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 SUPERFAMILY SSF56059 113 314 1.59E-52 T 28-03-2018 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 SUPERFAMILY SSF52440 19 113 3.55E-25 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Pfam PF07478 D-ala D-ala ligase C-terminus 121 311 3.4E-54 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 PIRSF PIRSF039102 18 67 1.7E-8 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 PIRSF PIRSF039102 59 320 2.2E-80 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Gene3D G3DSA:3.40.50.20 15 115 2.7E-29 T 28-03-2018 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 256 285 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 19 314 4.8E-101 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Gene3D G3DSA:3.30.470.20 183 320 8.6E-35 T 28-03-2018 SmaCSM2_RS03270 baa6bec9c11789e5076a608c747bdbdf 320 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 18 315 35.084 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS04655 965024d34a44dd8f6c0a14596e3652dc 373 Pfam PF13271 Domain of unknown function (DUF4062) 2 83 3.1E-19 T 28-03-2018 IPR025139 Domain of unknown function DUF4062 SmaCSM2_RS14905 58ce8ebf84bad41abf3745b0bdbf1755 120 SUPERFAMILY SSF103196 5 108 3.4E-5 T 28-03-2018 SmaCSM2_RS14905 58ce8ebf84bad41abf3745b0bdbf1755 120 Gene3D G3DSA:3.30.450.30 2 119 3.0E-22 T 28-03-2018 SmaCSM2_RS20630 dfa44f98dc70d8d576e4a87b7052a1b3 220 Gene3D G3DSA:1.10.340.20 135 215 1.0E-8 T 28-03-2018 SmaCSM2_RS13455 f96092b269481e672f16b3dbb1683c08 403 SUPERFAMILY SSF103473 7 391 2.22E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS13455 f96092b269481e672f16b3dbb1683c08 403 Gene3D G3DSA:1.20.1250.20 7 202 2.3E-27 T 28-03-2018 SmaCSM2_RS13455 f96092b269481e672f16b3dbb1683c08 403 Pfam PF07690 Major Facilitator Superfamily 23 337 6.3E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS13455 f96092b269481e672f16b3dbb1683c08 403 Gene3D G3DSA:1.20.1250.20 203 398 5.4E-19 T 28-03-2018 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 SUPERFAMILY SSF88946 3 78 2.75E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 154 3.1E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 Pfam PF04542 Sigma-70 region 2 4 64 2.2E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 Gene3D G3DSA:1.10.1740.10 1 68 1.4E-9 T 28-03-2018 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 Pfam PF08281 Sigma-70, region 4 99 148 2.5E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 SUPERFAMILY SSF88659 79 156 3.71E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS05965 62bbdc0ca853f8b27a821dec31af08dc 166 Gene3D G3DSA:1.10.10.10 76 160 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS14460 0628252bef11444fa32415b11eba8ba3 268 SUPERFAMILY SSF56317 1 258 8.11E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS14460 0628252bef11444fa32415b11eba8ba3 268 Gene3D G3DSA:3.60.110.10 1 266 4.6E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS14460 0628252bef11444fa32415b11eba8ba3 268 Pfam PF00795 Carbon-nitrogen hydrolase 6 248 8.7E-32 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS09110 3e0d77d09b71342eb57aab5bfc856419 1258 Gene3D G3DSA:3.40.50.300 199 454 5.4E-4 T 28-03-2018 SmaCSM2_RS02820 6b14c54a2c5377f41219bc2e26d7b170 320 Gene3D G3DSA:3.90.550.10 2 285 4.9E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02820 6b14c54a2c5377f41219bc2e26d7b170 320 SUPERFAMILY SSF53448 5 224 3.47E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02820 6b14c54a2c5377f41219bc2e26d7b170 320 Pfam PF00535 Glycosyl transferase family 2 6 180 1.7E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS11630 1b7d9744d01d7cf7d4defe52b5d5f824 450 Gene3D G3DSA:3.90.820.10 143 187 5.8E-5 T 28-03-2018 SmaCSM2_RS11630 1b7d9744d01d7cf7d4defe52b5d5f824 450 Gene3D G3DSA:2.20.25.10 75 114 2.8E-6 T 28-03-2018 SmaCSM2_RS17280 29da6fddb7f0d58744adb4f79e4e4606 218 Gene3D G3DSA:1.10.287.540 59 94 3.4E-10 T 28-03-2018 SmaCSM2_RS17280 29da6fddb7f0d58744adb4f79e4e4606 218 PIRSF PIRSF016482 1 216 2.1E-83 T 28-03-2018 IPR007445 Pilus assembly protein, PilO SmaCSM2_RS17280 29da6fddb7f0d58744adb4f79e4e4606 218 Gene3D G3DSA:3.30.70.60 95 210 3.6E-26 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SmaCSM2_RS17280 29da6fddb7f0d58744adb4f79e4e4606 218 Pfam PF04350 Pilus assembly protein, PilO 51 200 1.2E-50 T 28-03-2018 IPR007445 Pilus assembly protein, PilO SmaCSM2_RS15625 7809c81d97b81cbc1004152d88be3549 194 Gene3D G3DSA:3.30.160.150 17 171 6.4E-36 T 28-03-2018 SmaCSM2_RS15625 7809c81d97b81cbc1004152d88be3549 194 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 2 163 22.739 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 SmaCSM2_RS15625 7809c81d97b81cbc1004152d88be3549 194 Pfam PF04390 Lipopolysaccharide-assembly 38 158 3.4E-5 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 SmaCSM2_RS18060 3eb578485dd772f227337e4ea379a9ea 138 SUPERFAMILY SSF54593 10 130 8.19E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS18060 3eb578485dd772f227337e4ea379a9ea 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 124 4.0E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS18060 3eb578485dd772f227337e4ea379a9ea 138 Gene3D G3DSA:3.10.180.10 3 135 2.2E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS14955 32d454218c94389e91ea7e88296ffc68 57 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 52 20.896 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS14955 32d454218c94389e91ea7e88296ffc68 57 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.3E-11 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS14955 32d454218c94389e91ea7e88296ffc68 57 PIRSF PIRSF036466 1 55 1.1E-20 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS11795 e2d97863cbd379e60a9e53f25d0978a5 392 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 19 376 2.3E-103 T 28-03-2018 IPR010640 Low temperature requirement A SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 Gene3D G3DSA:3.30.70.270 349 511 8.4E-50 T 28-03-2018 SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 SMART SM00267 338 512 1.3E-44 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 351 510 8.6E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 SUPERFAMILY SSF55073 357 510 9.42E-43 T 28-03-2018 IPR029787 Nucleotide cyclase SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 508 3.7E-39 T 28-03-2018 IPR000160 GGDEF domain SmaCSM2_RS19860 af1183b30930df01542e3b29b607e5c4 512 Gene3D G3DSA:1.20.1270.60 73 348 1.8E-4 T 28-03-2018 SmaCSM2_RS13975 969d0fced52b357489973c5eeae49115 314 Pfam PF06189 5'-nucleotidase 38 312 4.2E-108 T 28-03-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 SmaCSM2_RS13975 969d0fced52b357489973c5eeae49115 314 Gene3D G3DSA:3.40.50.1000 168 306 4.9E-21 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS20000 a5420a1917785413427fabebb441358a 114 SUPERFAMILY SSF69118 14 110 8.51E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS20000 a5420a1917785413427fabebb441358a 114 Gene3D G3DSA:1.20.1290.10 1 113 3.4E-21 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS20000 a5420a1917785413427fabebb441358a 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 91 9.2E-16 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS20000 a5420a1917785413427fabebb441358a 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 107 1.2E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS20945 898bd7a5a39ce2b768c422e72e911b22 265 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SmaCSM2_RS20945 898bd7a5a39ce2b768c422e72e911b22 265 PIRSF PIRSF005902 1 264 3.4E-71 T 28-03-2018 IPR001130 TatD family GO:0016788 SmaCSM2_RS20945 898bd7a5a39ce2b768c422e72e911b22 265 Gene3D G3DSA:3.20.20.140 1 265 4.5E-81 T 28-03-2018 SmaCSM2_RS20945 898bd7a5a39ce2b768c422e72e911b22 265 Pfam PF01026 TatD related DNase 4 259 1.7E-67 T 28-03-2018 IPR001130 TatD family GO:0016788 SmaCSM2_RS20945 898bd7a5a39ce2b768c422e72e911b22 265 SUPERFAMILY SSF51556 3 261 4.23E-81 T 28-03-2018 IPR032466 Metal-dependent hydrolase SmaCSM2_RS07630 524529d111722c5340974f006cd459e5 201 Gene3D G3DSA:1.10.530.10 35 195 2.7E-16 T 28-03-2018 SmaCSM2_RS07630 524529d111722c5340974f006cd459e5 201 Pfam PF01464 Transglycosylase SLT domain 41 162 6.8E-7 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SmaCSM2_RS07630 524529d111722c5340974f006cd459e5 201 SUPERFAMILY SSF53955 108 181 3.97E-16 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS07630 524529d111722c5340974f006cd459e5 201 SUPERFAMILY SSF53955 38 80 3.97E-16 T 28-03-2018 IPR023346 Lysozyme-like domain SmaCSM2_RS01590 0200290063d934f206779cab84882f53 299 Pfam PF05036 Sporulation related domain 224 296 9.6E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01590 0200290063d934f206779cab84882f53 299 Gene3D G3DSA:3.30.70.1070 220 299 2.3E-14 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS01590 0200290063d934f206779cab84882f53 299 SUPERFAMILY SSF110997 222 297 8.5E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SmaCSM2_RS20770 7a8eed83d38b424d1189f0d69527ec33 190 Pfam PF06693 Protein of unknown function (DUF1190) 30 185 5.3E-34 T 28-03-2018 IPR009576 Biofilm formation YgiB SmaCSM2_RS18555 b56dfd2d2efd203ce191e42785dd4924 188 Pfam PF07209 Protein of unknown function (DUF1415) 12 179 3.0E-69 T 28-03-2018 IPR009858 Protein of unknown function DUF1415 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 Pfam PF01207 Dihydrouridine synthase (Dus) 13 313 3.0E-104 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 Gene3D G3DSA:3.20.20.70 8 241 2.4E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 SUPERFAMILY SSF51395 11 318 7.32E-90 T 28-03-2018 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.672 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 Gene3D G3DSA:1.10.1200.80 251 326 6.8E-23 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 PIRSF PIRSF006621 1 327 2.2E-109 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SmaCSM2_RS03410 7483c7fa4301383b607160e4402fb798 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 317 7.8E-122 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS21470 2a6ad7cccf5f87cfdd7fbeebe803f775 299 Pfam PF04366 Las17-binding protein actin regulator 99 206 5.5E-30 T 28-03-2018 IPR007461 Ysc84 actin-binding domain SmaCSM2_RS14895 4795c846b3125c20341790eb392cfd29 183 Gene3D G3DSA:3.40.50.300 2 170 1.7E-17 T 28-03-2018 SmaCSM2_RS14895 4795c846b3125c20341790eb392cfd29 183 Pfam PF08477 Ras of Complex, Roc, domain of DAPkinase 7 121 2.8E-6 T 28-03-2018 SmaCSM2_RS14895 4795c846b3125c20341790eb392cfd29 183 SUPERFAMILY SSF52540 4 153 6.89E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS21320 4d3a95e9c585ec3d9733e58c68ac34b5 113 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 21 104 2.0E-40 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS21320 4d3a95e9c585ec3d9733e58c68ac34b5 113 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 26 97 2.4E-21 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS21320 4d3a95e9c585ec3d9733e58c68ac34b5 113 PIRSF PIRSF028440 2 113 2.7E-47 T 28-03-2018 IPR014546 Uncharacterised conserved protein, lipid A biosynthesis SmaCSM2_RS21320 4d3a95e9c585ec3d9733e58c68ac34b5 113 SMART SM01259 26 99 9.1E-23 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 SmaCSM2_RS08440 544593a8144f2e9542cf871a78cd3ad1 128 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 116 5.9E-15 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08440 544593a8144f2e9542cf871a78cd3ad1 128 Gene3D G3DSA:1.20.1300.10 15 127 1.1E-17 T 28-03-2018 SmaCSM2_RS08440 544593a8144f2e9542cf871a78cd3ad1 128 SUPERFAMILY SSF81343 12 122 6.1E-25 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SmaCSM2_RS08440 544593a8144f2e9542cf871a78cd3ad1 128 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 17 120 3.3E-27 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 SmaCSM2_RS14375 bfdd20e79a2aeac1455c563b9a1b5202 295 Gene3D G3DSA:3.60.10.10 29 291 1.7E-40 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS14375 bfdd20e79a2aeac1455c563b9a1b5202 295 SUPERFAMILY SSF56219 46 289 1.28E-39 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS14375 bfdd20e79a2aeac1455c563b9a1b5202 295 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 50 282 4.5E-17 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS06090 397e7eac302e7d3893838d13b9730f83 144 Pfam PF08818 Domain of unknown function (DU1801) 43 136 1.6E-13 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 SmaCSM2_RS06090 397e7eac302e7d3893838d13b9730f83 144 SUPERFAMILY SSF159888 30 142 1.96E-27 T 28-03-2018 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 SUPERFAMILY SSF53383 1 423 2.56E-134 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 Gene3D G3DSA:3.40.640.10 182 313 4.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 3.3E-191 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 427 106.217 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 Pfam PF00202 Aminotransferase class-III 35 396 1.6E-83 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 Gene3D G3DSA:3.90.1150.10 1 181 2.6E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS17530 8420c7f0951fac5d4857fb8748ae0754 429 Gene3D G3DSA:3.90.1150.10 314 429 5.5E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS00780 41928930ecd04c598db58816d1c623b1 324 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 20 317 3.1E-75 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SmaCSM2_RS00780 41928930ecd04c598db58816d1c623b1 324 Pfam PF04261 Dyp-type peroxidase family 20 317 7.7E-80 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SmaCSM2_RS00780 41928930ecd04c598db58816d1c623b1 324 SUPERFAMILY SSF54909 19 322 2.5E-93 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS18370 12b4d62990a654fb821a5386e9bcd30d 161 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 152 5.9E-31 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SmaCSM2_RS18370 12b4d62990a654fb821a5386e9bcd30d 161 Pfam PF04093 rod shape-determining protein MreD 7 153 1.7E-30 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SmaCSM2_RS18370 12b4d62990a654fb821a5386e9bcd30d 161 PIRSF PIRSF018472 1 160 4.2E-48 T 28-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 Pfam PF07687 Peptidase dimerisation domain 202 299 1.1E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 Gene3D G3DSA:3.40.630.10 8 286 9.0E-67 T 28-03-2018 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 PIRSF PIRSF005962 21 404 4.8E-124 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 Gene3D G3DSA:3.40.630.10 287 406 1.3E-22 T 28-03-2018 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 SUPERFAMILY SSF53187 22 215 3.14E-86 T 28-03-2018 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 SUPERFAMILY SSF53187 316 403 3.14E-86 T 28-03-2018 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 SUPERFAMILY SSF55031 201 314 1.96E-31 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 33 387 1.3E-108 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SmaCSM2_RS09270 571158e97a82083b29f69a696e021ba0 406 Pfam PF01546 Peptidase family M20/M25/M40 91 398 1.1E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SmaCSM2_RS08280 7ed6d33e4eda2bb872c87f98822ffcdf 269 SUPERFAMILY SSF53613 9 260 4.99E-75 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS08280 7ed6d33e4eda2bb872c87f98822ffcdf 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 9 254 6.6E-88 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SmaCSM2_RS08280 7ed6d33e4eda2bb872c87f98822ffcdf 269 Pfam PF08543 Phosphomethylpyrimidine kinase 16 255 9.9E-87 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SmaCSM2_RS08280 7ed6d33e4eda2bb872c87f98822ffcdf 269 Gene3D G3DSA:3.40.1190.20 4 266 5.6E-59 T 28-03-2018 IPR029056 Ribokinase-like SmaCSM2_RS11060 ec41975a85bfc5c3cc8857466d442f0a 1160 Gene3D G3DSA:3.40.50.300 38 257 0.002 T 28-03-2018 SmaCSM2_RS03330 eff2d48eed3cfbdebb7d44ffeef7fa6e 348 Gene3D G3DSA:3.30.565.10 179 329 4.4E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03330 eff2d48eed3cfbdebb7d44ffeef7fa6e 348 SUPERFAMILY SSF55874 228 331 4.88E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS03330 eff2d48eed3cfbdebb7d44ffeef7fa6e 348 Pfam PF06580 Histidine kinase 166 244 1.5E-22 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 TIGRFAM TIGR02052 MerP: mercuric transport protein periplasmic component 1 91 2.8E-44 T 28-03-2018 IPR011795 Mercuric transport protein periplasmic component GO:0015097|GO:0015694|GO:0042597|GO:0045340|GO:0046689 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 57 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 SUPERFAMILY SSF55008 17 89 4.71E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 Gene3D G3DSA:3.30.70.100 20 91 5.1E-24 T 28-03-2018 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 Pfam PF00403 Heavy-metal-associated domain 25 85 2.6E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 31 47 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 62 76 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 2 20 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 20 31 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 76 90 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS10725 182609aea4308b306bf259527d0943ca 91 PRINTS PR00946 Mercury scavenger protein signature 47 62 3.3E-59 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 SmaCSM2_RS04605 953729e36733ec1f8821404dd7bafe76 483 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 2 43 2.7E-6 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SmaCSM2_RS12430 f988901d2cec7d8b2bd77252967ae372 176 Gene3D G3DSA:3.10.450.50 25 169 2.3E-17 T 28-03-2018 SmaCSM2_RS12430 f988901d2cec7d8b2bd77252967ae372 176 SUPERFAMILY SSF54427 29 170 1.83E-14 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS21240 d4766577938e1e2f52b801d30f92b38e 108 Gene3D G3DSA:3.40.50.2300 4 41 3.9E-8 T 28-03-2018 SmaCSM2_RS21240 d4766577938e1e2f52b801d30f92b38e 108 PIRSF PIRSF029416 2 108 6.9E-50 T 28-03-2018 IPR016919 Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 SmaCSM2_RS21240 d4766577938e1e2f52b801d30f92b38e 108 Gene3D G3DSA:3.40.50.2300 42 102 0.0041 T 28-03-2018 SmaCSM2_RS21240 d4766577938e1e2f52b801d30f92b38e 108 SUPERFAMILY SSF52788 1 107 2.62E-19 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS08810 f45d78dd1b45d01fb34a63316227bd4f 197 Pfam PF03641 Possible lysine decarboxylase 46 172 5.6E-38 T 28-03-2018 IPR031100 LOG family SmaCSM2_RS08810 f45d78dd1b45d01fb34a63316227bd4f 197 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 1.0E-56 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SmaCSM2_RS08810 f45d78dd1b45d01fb34a63316227bd4f 197 Gene3D G3DSA:3.40.50.450 1 197 1.9E-59 T 28-03-2018 SmaCSM2_RS08810 f45d78dd1b45d01fb34a63316227bd4f 197 SUPERFAMILY SSF102405 1 179 1.27E-61 T 28-03-2018 SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 SMART SM00922 141 239 2.4E-21 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 Gene3D G3DSA:3.30.390.10 1 131 4.6E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 SUPERFAMILY SSF51604 112 355 1.57E-63 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 124 1.7E-19 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 Gene3D G3DSA:3.20.20.120 132 357 2.6E-59 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 Pfam PF13378 Enolase C-terminal domain-like 151 355 9.7E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SmaCSM2_RS01925 03b4cc4a8766bb25cf0bd63cd52b8591 364 SUPERFAMILY SSF54826 1 125 6.79E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SmaCSM2_RS20765 70c8bb679217be3dfde29f8a2d52fbcb 392 SUPERFAMILY SSF52440 173 276 8.06E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SmaCSM2_RS20765 70c8bb679217be3dfde29f8a2d52fbcb 392 SUPERFAMILY SSF56059 1 169 3.53E-79 T 28-03-2018 SmaCSM2_RS20765 70c8bb679217be3dfde29f8a2d52fbcb 392 SUPERFAMILY SSF56059 266 380 3.53E-79 T 28-03-2018 SmaCSM2_RS20765 70c8bb679217be3dfde29f8a2d52fbcb 392 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 382 4.2E-146 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 SMART SM00833 263 416 4.2E-39 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 263 416 3.7E-24 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 Gene3D G3DSA:3.40.50.300 8 236 2.8E-53 T 28-03-2018 SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 SUPERFAMILY SSF52540 6 315 2.66E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 Gene3D G3DSA:3.30.1220.10 247 417 4.1E-33 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SmaCSM2_RS02195 16383ea44147cca126df2625d1222872 441 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 216 2.0E-53 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 Gene3D G3DSA:1.20.1560.10 2 326 1.1E-24 T 28-03-2018 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 Gene3D G3DSA:3.40.50.300 327 552 8.0E-53 T 28-03-2018 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 SUPERFAMILY SSF52540 331 552 4.38E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 11 535 4.6E-126 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 SUPERFAMILY SSF90123 8 328 1.7E-30 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 Pfam PF00005 ABC transporter 358 505 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS14525 94c4cc651d6cfaecfa2e770f563d6b3e 557 SMART SM00382 367 550 7.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08725 c84f7115a1b5ddcbd8e5327950d31928 421 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 197 393 2.0E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS08725 c84f7115a1b5ddcbd8e5327950d31928 421 Gene3D G3DSA:3.40.50.1110 191 399 7.4E-31 T 28-03-2018 SmaCSM2_RS08725 c84f7115a1b5ddcbd8e5327950d31928 421 SUPERFAMILY SSF52266 192 401 5.66E-49 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS04510 868b8f3bac4e090e6e5e4338eb59c3c4 348 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 72 302 5.0E-46 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 SmaCSM2_RS04510 868b8f3bac4e090e6e5e4338eb59c3c4 348 Gene3D G3DSA:3.40.50.2000 8 156 1.7E-27 T 28-03-2018 SmaCSM2_RS04510 868b8f3bac4e090e6e5e4338eb59c3c4 348 SUPERFAMILY SSF53756 8 344 3.14E-74 T 28-03-2018 SmaCSM2_RS04510 868b8f3bac4e090e6e5e4338eb59c3c4 348 Gene3D G3DSA:3.40.50.2000 157 347 1.5E-38 T 28-03-2018 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 Gene3D G3DSA:2.40.170.20 169 747 8.9E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 SUPERFAMILY SSF56935 33 747 3.89E-93 T 28-03-2018 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 Pfam PF00593 TonB dependent receptor 261 746 2.9E-45 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 Gene3D G3DSA:2.170.130.10 33 167 2.0E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 150 1.4E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS14160 2ce52cc8baee6523076ccef93919542f 747 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 730 747 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site SmaCSM2_RS05205 7ef115ffaaf6fa055e3530b29f2b8d54 89 Pfam PF04226 Transglycosylase associated protein 40 86 6.9E-12 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SmaCSM2_RS10310 a1483bec283c045fe3890d5b6dade88e 218 Pfam PF13144 Chaperone for flagella basal body P-ring formation 52 216 2.6E-40 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal SmaCSM2_RS10310 a1483bec283c045fe3890d5b6dade88e 218 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 81 216 2.2E-38 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal SmaCSM2_RS10310 a1483bec283c045fe3890d5b6dade88e 218 Gene3D G3DSA:3.90.1210.10 91 156 2.5E-14 T 28-03-2018 SmaCSM2_RS10310 a1483bec283c045fe3890d5b6dade88e 218 SMART SM00858 93 155 1.7E-11 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SmaCSM2_RS03255 0254765204fa0685b311247e66c69bb6 441 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 17 383 37.341 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 SmaCSM2_RS03255 0254765204fa0685b311247e66c69bb6 441 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 19 372 1.6E-123 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 SmaCSM2_RS03255 0254765204fa0685b311247e66c69bb6 441 Pfam PF01098 Cell cycle protein 21 373 1.7E-98 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 422 44.902 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 421 4.3E-178 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 412 2.9E-112 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 SUPERFAMILY SSF55205 1 422 6.8E-142 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 Gene3D G3DSA:3.65.10.10 21 225 1.2E-48 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS05135 f6e0e976f945716b7a430e99623e2a8a 423 Gene3D G3DSA:3.65.10.10 226 423 3.4E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SmaCSM2_RS08200 e8e8cd85b093e48bff7e945228760bc7 531 Pfam PF09423 PhoD-like phosphatase 164 498 1.5E-97 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SmaCSM2_RS08200 e8e8cd85b093e48bff7e945228760bc7 531 SUPERFAMILY SSF56300 160 497 4.14E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS08200 e8e8cd85b093e48bff7e945228760bc7 531 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 55 151 4.0E-30 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SmaCSM2_RS08200 e8e8cd85b093e48bff7e945228760bc7 531 Gene3D G3DSA:3.60.21.10 158 516 2.9E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS08200 e8e8cd85b093e48bff7e945228760bc7 531 Gene3D G3DSA:2.60.40.380 51 155 2.6E-5 T 28-03-2018 SmaCSM2_RS08815 5cc76b03f375765cfc1bfadb888ef933 498 Pfam PF00202 Aminotransferase class-III 84 485 9.3E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS08815 5cc76b03f375765cfc1bfadb888ef933 498 SUPERFAMILY SSF53383 72 487 9.34E-53 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS08815 5cc76b03f375765cfc1bfadb888ef933 498 Gene3D G3DSA:3.90.1150.10 376 498 1.4E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS08815 5cc76b03f375765cfc1bfadb888ef933 498 Gene3D G3DSA:3.40.640.10 34 375 1.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 SUPERFAMILY SSF46604 87 136 1.86E-10 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 1.0E-35 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 SUPERFAMILY SSF51344 3 85 5.49E-23 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 9.7E-9 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 Gene3D G3DSA:2.60.15.10 1 89 6.9E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 132 3.6E-43 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 9.4E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 20.023 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SmaCSM2_RS18685 df9d29210ed22ff0c80de2f454bbac9a 140 Gene3D G3DSA:1.20.5.440 90 130 1.8E-4 T 28-03-2018 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 Pfam PF02547 Queuosine biosynthesis protein 16 350 6.2E-129 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 SUPERFAMILY SSF111337 14 351 4.97E-131 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 13 351 45.936 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 14 350 1.2E-127 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 Gene3D G3DSA:3.40.1780.10 183 351 1.3E-64 T 28-03-2018 SmaCSM2_RS08820 fbae52c7ffbb158ceb2c2f8040c12a54 355 Gene3D G3DSA:3.40.1780.10 7 133 1.0E-29 T 28-03-2018 SmaCSM2_RS12035 eeaa2a4be3fe2de261fd9ba35de0a155 254 SUPERFAMILY SSF56925 107 253 3.3E-19 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 Gene3D G3DSA:2.170.130.10 20 156 6.3E-34 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 Gene3D G3DSA:2.40.170.20 157 611 2.8E-71 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 SUPERFAMILY SSF56935 30 610 9.47E-120 T 28-03-2018 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 TIGRFAM TIGR01779 TonB-B12: TonB-dependent vitamin B12 receptor 10 612 1.8E-190 T 28-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 Pfam PF00593 TonB dependent receptor 216 611 4.9E-48 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS02515 d74ed60f958d99a6c093b5c299c38736 613 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 149 8.8E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS21725 2cd62468a70e9a21a80c79b9be619cb5 320 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 311 2.3E-121 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SmaCSM2_RS21725 2cd62468a70e9a21a80c79b9be619cb5 320 Pfam PF03741 Integral membrane protein TerC family 80 282 6.3E-56 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SmaCSM2_RS15805 c0fc6822c1d2110f17f01bf34128cfa7 185 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 6 185 7.8E-53 T 28-03-2018 IPR018636 Protein of unknown function DUF2058 SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 SUPERFAMILY SSF89360 1 88 1.59E-13 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 Gene3D G3DSA:3.30.300.130 105 189 3.3E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 SUPERFAMILY SSF117916 105 186 2.4E-22 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 Gene3D G3DSA:2.60.300.12 1 104 9.5E-9 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 Pfam PF01106 NifU-like domain 115 179 4.7E-20 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 193 38.198 T 28-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 SmaCSM2_RS14345 5ecc0e85248f56831eec3862cc62326e 199 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 120 179 5.0E-26 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 Gene3D G3DSA:1.25.40.10 95 144 2.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 Gene3D G3DSA:1.25.40.10 145 239 3.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 Gene3D G3DSA:1.25.40.10 10 94 4.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 SUPERFAMILY SSF48452 80 204 2.95E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 SMART SM00028 147 180 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS12755 09fd6b5ff0decea05d21070c16f4f1c8 296 SMART SM00028 113 146 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SmaCSM2_RS20265 d720216e2207490da46a7b3b64ac5bba 354 SUPERFAMILY SSF51395 1 352 4.28E-116 T 28-03-2018 SmaCSM2_RS20265 d720216e2207490da46a7b3b64ac5bba 354 Gene3D G3DSA:3.20.20.70 1 354 4.0E-125 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS20265 d720216e2207490da46a7b3b64ac5bba 354 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 330 2.0E-84 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS16235 b950df0a6ba032b32dfc5ac26a72015b 67 Pfam PF07311 Dodecin 3 67 3.4E-21 T 28-03-2018 IPR009923 Dodecin SmaCSM2_RS16235 b950df0a6ba032b32dfc5ac26a72015b 67 SUPERFAMILY SSF89807 1 67 1.57E-17 T 28-03-2018 IPR009923 Dodecin SmaCSM2_RS16235 b950df0a6ba032b32dfc5ac26a72015b 67 Gene3D G3DSA:3.30.1660.10 2 67 1.6E-22 T 28-03-2018 IPR025543 Dodecin-like SmaCSM2_RS04835 4a9aeeb573c4d7b6538cb9abdef78cf1 117 Gene3D G3DSA:2.40.10.220 31 104 2.2E-5 T 28-03-2018 SmaCSM2_RS04835 4a9aeeb573c4d7b6538cb9abdef78cf1 117 Pfam PF07238 PilZ domain 14 103 7.2E-8 T 28-03-2018 IPR009875 PilZ domain GO:0035438 SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 Gene3D G3DSA:3.40.47.10 1 261 5.5E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 SUPERFAMILY SSF53901 5 254 4.55E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 Gene3D G3DSA:3.40.47.10 263 410 6.3E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 158 174 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 249 3.6E-39 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 366 5.4E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 SMART SM00825 Beta-ketoacyl synthase 7 412 5.8E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SmaCSM2_RS21060 07a4604160c243c0a4d23e04693c4d38 412 SUPERFAMILY SSF53901 217 410 2.78E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS18410 adcb2d8246ec43e9f4bcf408af6e6dd3 150 Gene3D G3DSA:3.40.140.10 3 150 4.1E-34 T 28-03-2018 SmaCSM2_RS18410 adcb2d8246ec43e9f4bcf408af6e6dd3 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 102 1.1E-16 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SmaCSM2_RS18410 adcb2d8246ec43e9f4bcf408af6e6dd3 150 SUPERFAMILY SSF53927 6 148 9.7E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SmaCSM2_RS01075 81997caa66114a458287abda019d2c83 366 SUPERFAMILY SSF52540 53 185 1.01E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01075 81997caa66114a458287abda019d2c83 366 Pfam PF03969 AFG1-like ATPase 7 361 1.4E-122 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 SmaCSM2_RS01075 81997caa66114a458287abda019d2c83 366 Gene3D G3DSA:3.40.50.300 44 360 1.6E-11 T 28-03-2018 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 SUPERFAMILY SSF55486 42 668 1.25E-140 T 28-03-2018 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 Pfam PF01431 Peptidase family M13 471 664 4.7E-42 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 478 490 1.6E-6 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 499 515 1.6E-6 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 572 583 1.6E-6 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 Gene3D G3DSA:3.40.390.10 39 279 6.0E-6 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 Gene3D G3DSA:3.40.390.10 339 669 5.5E-67 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS15445 577f1be918dac888b6ff218f269385d0 669 Pfam PF05649 Peptidase family M13 42 416 1.8E-68 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PRINTS PR00116 Arginase signature 260 274 5.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PRINTS PR00116 Arginase signature 96 111 5.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PRINTS PR00116 Arginase signature 225 254 5.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PRINTS PR00116 Arginase signature 177 195 5.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PRINTS PR00116 Arginase signature 123 150 5.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 SUPERFAMILY SSF52768 6 301 4.14E-88 T 28-03-2018 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 TIGRFAM TIGR01229 rocF_arginase: arginase 8 302 4.7E-88 T 28-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 PIRSF PIRSF036979 2 302 2.9E-32 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 Pfam PF00491 Arginase family 7 298 9.7E-76 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SmaCSM2_RS01380 dcbe41b5fa4ad1615b835275436b3a57 306 Gene3D G3DSA:3.40.800.10 1 302 1.6E-83 T 28-03-2018 SmaCSM2_RS06530 6ed82ecdad41f4cb03a266173bbfd21b 290 Pfam PF00892 EamA-like transporter family 20 144 6.5E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06530 6ed82ecdad41f4cb03a266173bbfd21b 290 Pfam PF00892 EamA-like transporter family 156 286 5.7E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06530 6ed82ecdad41f4cb03a266173bbfd21b 290 SUPERFAMILY SSF103481 192 287 1.57E-16 T 28-03-2018 SmaCSM2_RS06530 6ed82ecdad41f4cb03a266173bbfd21b 290 SUPERFAMILY SSF103481 48 146 6.93E-18 T 28-03-2018 SmaCSM2_RS09885 0a6fd22fc1de26b2ac07faff3c65c210 461 Gene3D G3DSA:3.40.605.10 2 250 9.8E-68 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09885 0a6fd22fc1de26b2ac07faff3c65c210 461 Gene3D G3DSA:3.40.309.10 251 442 2.5E-66 T 28-03-2018 SmaCSM2_RS09885 0a6fd22fc1de26b2ac07faff3c65c210 461 Pfam PF00171 Aldehyde dehydrogenase family 7 456 6.7E-135 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09885 0a6fd22fc1de26b2ac07faff3c65c210 461 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 260 271 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS09885 0a6fd22fc1de26b2ac07faff3c65c210 461 SUPERFAMILY SSF53720 7 459 4.32E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SmaCSM2_RS07765 3dac155da50e2f5968fb02a7ec18abd7 175 Pfam PF11358 Protein of unknown function (DUF3158) 11 165 1.6E-72 T 28-03-2018 IPR021502 Protein of unknown function DUF3158 SmaCSM2_RS20640 126ed7f5f7bb84418b53dd099385a2a8 189 Pfam PF12395 Protein of unknown function 112 180 1.7E-10 T 28-03-2018 IPR022123 Protein of unknown function DUF3658 SmaCSM2_RS20640 126ed7f5f7bb84418b53dd099385a2a8 189 ProDom PD069398 YJEN 114 184 2.0E-5 T 28-03-2018 IPR020528 Uncharacterised protein family YjeN SmaCSM2_RS15795 2045f1700d3f8b470665d27dad8c3db9 197 Pfam PF00924 Mechanosensitive ion channel 63 184 5.7E-14 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SmaCSM2_RS15795 2045f1700d3f8b470665d27dad8c3db9 197 Gene3D G3DSA:2.30.30.60 124 183 1.0E-13 T 28-03-2018 SmaCSM2_RS15795 2045f1700d3f8b470665d27dad8c3db9 197 SUPERFAMILY SSF50182 109 183 5.56E-10 T 28-03-2018 IPR010920 LSM domain SmaCSM2_RS15520 0f339cbb694f081e0c3c3b7bd8eaaaae 55 Gene3D G3DSA:3.30.420.10 6 55 7.5E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS15520 0f339cbb694f081e0c3c3b7bd8eaaaae 55 Pfam PF00665 Integrase core domain 11 48 3.9E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS15520 0f339cbb694f081e0c3c3b7bd8eaaaae 55 SUPERFAMILY SSF53098 12 50 2.12E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS16005 ad09eb43d69683ffa6fa453de976f878 693 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 466 594 4.2E-36 T 28-03-2018 IPR025299 CstA, C-terminal domain SmaCSM2_RS16005 ad09eb43d69683ffa6fa453de976f878 693 Pfam PF02554 Carbon starvation protein CstA 31 408 8.4E-167 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 SmaCSM2_RS06100 9ded255eb29336a5c48973238bc88ddc 490 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 425 2.5E-71 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS06100 9ded255eb29336a5c48973238bc88ddc 490 Pfam PF01554 MatE 23 184 5.2E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS06100 9ded255eb29336a5c48973238bc88ddc 490 Pfam PF01554 MatE 252 412 1.5E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS06100 9ded255eb29336a5c48973238bc88ddc 490 PIRSF PIRSF006603 1 460 2.4E-116 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 SUPERFAMILY SSF75217 1 247 4.32E-91 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 1.7E-81 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 Gene3D G3DSA:3.40.1280.10 1 166 2.2E-67 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 PIRSF PIRSF000386 1 251 3.9E-90 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 252 103.603 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 Gene3D G3DSA:1.10.1270.20 167 252 1.2E-27 T 28-03-2018 SmaCSM2_RS06075 065639677ae483305c999fb3813a8374 252 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 223 2.8E-53 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 Gene3D G3DSA:1.10.10.10 1 88 7.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 Gene3D G3DSA:3.40.190.10 171 262 8.2E-23 T 28-03-2018 SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 SUPERFAMILY SSF46785 4 86 7.18E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 Gene3D G3DSA:3.40.190.10 89 170 7.9E-11 T 28-03-2018 SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 SUPERFAMILY SSF53850 87 296 5.25E-45 T 28-03-2018 SmaCSM2_RS11935 64f59c67fdd9e7c1b5d991c904565db4 313 Pfam PF03466 LysR substrate binding domain 88 291 6.3E-43 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS11685 4d4a00ac9f04ce79d44d0380bb3bcc47 393 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 261 1.9E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS11685 4d4a00ac9f04ce79d44d0380bb3bcc47 393 Gene3D G3DSA:1.20.1600.10 60 319 1.7E-24 T 28-03-2018 SmaCSM2_RS11685 4d4a00ac9f04ce79d44d0380bb3bcc47 393 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 376 7.0E-44 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS11685 4d4a00ac9f04ce79d44d0380bb3bcc47 393 SUPERFAMILY SSF111369 46 231 3.92E-21 T 28-03-2018 SmaCSM2_RS03050 30ccbc97e349b39cff96b8fa9c4c311d 345 Pfam PF00419 Fimbrial protein 192 344 6.0E-17 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 SmaCSM2_RS03050 30ccbc97e349b39cff96b8fa9c4c311d 345 SUPERFAMILY SSF49401 195 345 1.29E-24 T 28-03-2018 IPR008966 Adhesion domain SmaCSM2_RS03050 30ccbc97e349b39cff96b8fa9c4c311d 345 Gene3D G3DSA:2.60.40.1090 28 173 0.024 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 SmaCSM2_RS03050 30ccbc97e349b39cff96b8fa9c4c311d 345 Gene3D G3DSA:2.60.40.1090 200 345 6.8E-29 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 SmaCSM2_RS02735 5e53525f1fbd55220844bf22ea45864c 314 Gene3D G3DSA:3.40.50.720 2 307 1.9E-33 T 28-03-2018 SmaCSM2_RS02735 5e53525f1fbd55220844bf22ea45864c 314 SUPERFAMILY SSF51735 7 266 3.96E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02735 5e53525f1fbd55220844bf22ea45864c 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 215 8.2E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SmaCSM2_RS20740 1e99391fc4493a2e136d72a41c69bcca 538 Pfam PF13559 Domain of unknown function (DUF4129) 460 531 6.5E-10 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 SmaCSM2_RS10295 57fbc42352aea346877789e6309f7541 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site SmaCSM2_RS10295 57fbc42352aea346877789e6309f7541 135 Pfam PF00460 Flagella basal body rod protein 7 34 3.7E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS10295 57fbc42352aea346877789e6309f7541 135 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 88 131 2.8E-10 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain SmaCSM2_RS10295 57fbc42352aea346877789e6309f7541 135 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 6 135 3.3E-42 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 Pfam PF00691 OmpA family 125 220 2.6E-22 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 Gene3D G3DSA:3.30.1330.60 84 231 5.2E-43 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 PRINTS PR01021 OMPA domain signature 156 171 3.1E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 PRINTS PR01021 OMPA domain signature 171 187 3.1E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 PRINTS PR01021 OMPA domain signature 126 148 3.1E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 SUPERFAMILY SSF103088 113 229 9.94E-40 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS08585 58a61f965e7127199d6431e092608fb3 231 Pfam PF13488 Glycine zipper 50 95 3.7E-11 T 28-03-2018 SmaCSM2_RS06780 4468a56daff7ec11f589ffa416def973 248 Pfam PF01925 Sulfite exporter TauE/SafE 12 241 1.5E-29 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SmaCSM2_RS15900 18b09a47df46f5a8951b318eb5888440 184 SUPERFAMILY SSF53271 7 183 1.57E-42 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS15900 18b09a47df46f5a8951b318eb5888440 184 Gene3D G3DSA:3.40.50.2020 5 184 4.2E-35 T 28-03-2018 SmaCSM2_RS15900 18b09a47df46f5a8951b318eb5888440 184 Pfam PF00156 Phosphoribosyl transferase domain 16 170 6.4E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SmaCSM2_RS01435 caa60866e6a4c7d232da9234678252af 299 SUPERFAMILY SSF103481 206 289 1.83E-11 T 28-03-2018 SmaCSM2_RS01435 caa60866e6a4c7d232da9234678252af 299 SUPERFAMILY SSF103481 58 147 2.55E-12 T 28-03-2018 SmaCSM2_RS01435 caa60866e6a4c7d232da9234678252af 299 TIGRFAM TIGR00688 rarD: protein RarD 10 263 8.1E-65 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 SmaCSM2_RS01435 caa60866e6a4c7d232da9234678252af 299 Pfam PF00892 EamA-like transporter family 11 146 2.2E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS01435 caa60866e6a4c7d232da9234678252af 299 Pfam PF00892 EamA-like transporter family 155 287 1.7E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS07365 c3e9b241e852f1a7405b3f246373498a 487 SUPERFAMILY SSF56954 33 476 1.7E-72 T 28-03-2018 SmaCSM2_RS07365 c3e9b241e852f1a7405b3f246373498a 487 Pfam PF02321 Outer membrane efflux protein 87 266 1.1E-11 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS07365 c3e9b241e852f1a7405b3f246373498a 487 Pfam PF02321 Outer membrane efflux protein 288 474 7.5E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS07365 c3e9b241e852f1a7405b3f246373498a 487 Gene3D G3DSA:1.20.1600.10 71 476 1.2E-60 T 28-03-2018 SmaCSM2_RS07365 c3e9b241e852f1a7405b3f246373498a 487 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 38 475 4.0E-63 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 SmaCSM2_RS07235 a0afb324939464b45121f75e84217049 173 Pfam PF14341 PilX N-terminal 19 67 1.9E-7 T 28-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 6 63 18.84 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 PIRSF PIRSF002211 1 63 3.2E-25 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 9 63 4.3E-19 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 Gene3D G3DSA:3.30.1390.20 9 63 3.4E-18 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 Pfam PF00327 Ribosomal protein L30p/L7e 10 59 2.4E-13 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SmaCSM2_RS04080 38ce3a8bc9165f12da64d0877704b5ea 63 SUPERFAMILY SSF55129 7 63 3.79E-17 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 4.8E-93 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 627 639 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 399 418 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 356 373 9.8E-47 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 Pfam PF01578 Cytochrome C assembly protein 89 295 1.4E-52 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 636 2.8E-221 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 SmaCSM2_RS14495 322e2c1af911a862d6153ba037e2f485 639 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 634 1.3E-117 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal SmaCSM2_RS20160 e6e1e0d3cc4863f6853f4dfd898c8c3e 163 Gene3D G3DSA:3.40.50.2300 1 141 1.7E-32 T 28-03-2018 SmaCSM2_RS20160 e6e1e0d3cc4863f6853f4dfd898c8c3e 163 SUPERFAMILY SSF52788 4 140 2.62E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS20160 e6e1e0d3cc4863f6853f4dfd898c8c3e 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 139 5.5E-17 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS20160 e6e1e0d3cc4863f6853f4dfd898c8c3e 163 SMART SM00226 3 141 2.2E-25 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 SUPERFAMILY SSF52833 1 84 1.84E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 Pfam PF00043 Glutathione S-transferase, C-terminal domain 132 197 3.3E-13 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 Gene3D G3DSA:3.40.30.10 1 101 3.7E-29 T 28-03-2018 SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 SUPERFAMILY SSF47616 78 208 1.2E-37 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 Gene3D G3DSA:1.20.1050.10 102 213 1.6E-33 T 28-03-2018 SmaCSM2_RS20850 704590dd6bba4cb9d336f670b1c5cc90 229 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 81 5.1E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 Pfam PF00691 OmpA family 248 343 3.0E-22 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 Gene3D G3DSA:3.30.1330.60 63 349 2.4E-40 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 PRINTS PR01021 OMPA domain signature 294 310 5.7E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 PRINTS PR01021 OMPA domain signature 279 294 5.7E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 PRINTS PR01021 OMPA domain signature 249 271 5.7E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS04615 d0254b20c295fb891398fa2275b1ff33 350 SUPERFAMILY SSF103088 243 348 9.55E-35 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS08130 a0363f5b15c798006e1e6a02212ea899 164 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 16 160 1.4E-48 T 28-03-2018 IPR008136 CinA, C-terminal SmaCSM2_RS08130 a0363f5b15c798006e1e6a02212ea899 164 Gene3D G3DSA:3.90.950.20 2 164 7.8E-52 T 28-03-2018 SmaCSM2_RS08130 a0363f5b15c798006e1e6a02212ea899 164 Pfam PF02464 Competence-damaged protein 14 161 2.2E-54 T 28-03-2018 IPR008136 CinA, C-terminal SmaCSM2_RS08130 a0363f5b15c798006e1e6a02212ea899 164 SUPERFAMILY SSF142433 8 160 4.32E-52 T 28-03-2018 IPR008136 CinA, C-terminal SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 Pfam PF00460 Flagella basal body rod protein 5 34 1.2E-7 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 SUPERFAMILY SSF64518 431 623 3.14E-26 T 28-03-2018 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 SUPERFAMILY SSF64518 165 445 6.28E-24 T 28-03-2018 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 Gene3D G3DSA:2.60.40.1170 406 596 9.8E-4 T 28-03-2018 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 4 341 2.3E-65 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 404 421 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 123 143 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 49 71 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 11 34 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 354 376 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 PRINTS PR01005 Flagellar hook-associated protein signature 156 180 5.0E-18 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 SmaCSM2_RS10255 41e0a10b4b359c4996b6b0400f69be91 626 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 568 621 2.5E-12 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 31 377 1.0E-104 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 SMART SM00729 30 247 1.4E-52 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 Pfam PF04055 Radical SAM superfamily 35 200 5.4E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 SUPERFAMILY SSF102114 23 406 4.05E-109 T 28-03-2018 SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 Pfam PF06969 HemN C-terminal domain 336 395 3.4E-11 T 28-03-2018 IPR010723 HemN, C-terminal SmaCSM2_RS17450 932fef46b6013e5fe781094cf997c2ce 408 Gene3D G3DSA:3.20.20.70 15 322 3.8E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 SUPERFAMILY SSF51735 3 241 1.27E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 Pfam PF00106 short chain dehydrogenase 3 191 2.9E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 Gene3D G3DSA:3.40.50.720 1 242 4.0E-41 T 28-03-2018 SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 47 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS02740 342641561bbc2d6a36e9eb84f482ffff 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS15375 b28ef39069b00a3437c5cc6b2558fb65 153 Pfam PF08875 Domain of unknown function (DUF1833) 18 131 1.5E-15 T 28-03-2018 IPR014974 Domain of unknown function DUF1833 SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 85 2.4E-23 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 288 1.3E-106 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 Gene3D G3DSA:1.10.150.130 1 107 5.4E-27 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 Pfam PF00589 Phage integrase family 108 272 9.4E-45 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 2 286 57.627 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 SUPERFAMILY SSF56349 5 279 6.77E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS18475 33492e2b682a6c8afe61ebb6ff12e2c3 296 Gene3D G3DSA:1.10.443.10 108 280 1.0E-45 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 78 294 1.7E-24 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 Gene3D G3DSA:2.40.50.100 76 132 7.0E-14 T 28-03-2018 SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 SUPERFAMILY SSF111369 66 299 1.02E-34 T 28-03-2018 SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 Gene3D G3DSA:2.40.50.100 178 330 3.2E-5 T 28-03-2018 SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 52 375 1.8E-64 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS13195 63414ac83226bd86c3e1d1f014dd4b44 387 Gene3D G3DSA:1.10.287.470 133 177 7.1E-8 T 28-03-2018 SmaCSM2_RS04710 fe4e7028e948bced5ec276a6dbb2a0c3 532 Pfam PF03389 MobA/MobL family 28 214 6.6E-43 T 28-03-2018 IPR005053 MobA/MobL protein SmaCSM2_RS18525 77816ef9941f5c77a877208cf69f5d1a 99 SUPERFAMILY SSF47413 12 86 1.34E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS18525 77816ef9941f5c77a877208cf69f5d1a 99 Pfam PF01381 Helix-turn-helix 22 68 2.2E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS18525 77816ef9941f5c77a877208cf69f5d1a 99 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 8 83 3.6E-30 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 SmaCSM2_RS18525 77816ef9941f5c77a877208cf69f5d1a 99 SMART SM00530 16 72 0.001 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS18525 77816ef9941f5c77a877208cf69f5d1a 99 Gene3D G3DSA:1.10.260.40 4 87 4.7E-11 T 28-03-2018 SmaCSM2_RS12990 0fa313a3dfbdc020f9ff2fd8e71fb3cc 204 Gene3D G3DSA:3.40.50.300 48 163 1.5E-29 T 28-03-2018 SmaCSM2_RS12990 0fa313a3dfbdc020f9ff2fd8e71fb3cc 204 PIRSF PIRSF037290 4 204 5.7E-72 T 28-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 SmaCSM2_RS12990 0fa313a3dfbdc020f9ff2fd8e71fb3cc 204 SUPERFAMILY SSF52540 50 161 4.25E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16160 11416690b5997a0c4a96962f224986f6 191 Gene3D G3DSA:1.20.1260.10 16 187 8.2E-45 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS16160 11416690b5997a0c4a96962f224986f6 191 Pfam PF00210 Ferritin-like domain 49 186 1.1E-28 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SmaCSM2_RS16160 11416690b5997a0c4a96962f224986f6 191 SUPERFAMILY SSF47240 43 186 6.89E-38 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS16160 11416690b5997a0c4a96962f224986f6 191 PIRSF PIRSF018063 24 191 9.0E-64 T 28-03-2018 IPR014490 DNA-binding protein from starved cells-like SmaCSM2_RS17640 158540a64e31bf60f718487ca21d5b46 141 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 16 137 7.8E-53 T 28-03-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 SmaCSM2_RS17640 158540a64e31bf60f718487ca21d5b46 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 134 1.2E-26 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS02655 1b7d68a7da6fb58b4d1d7eb229ebafd4 78 Pfam PF04325 Protein of unknown function (DUF465) 20 66 9.2E-11 T 28-03-2018 IPR007420 Protein of unknown function DUF465 SmaCSM2_RS14035 9dbb1252acc67b5821af56331272c5a4 395 SUPERFAMILY SSF103473 5 380 3.14E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS14035 9dbb1252acc67b5821af56331272c5a4 395 PIRSF PIRSF004925 1 394 1.3E-86 T 28-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter SmaCSM2_RS14035 9dbb1252acc67b5821af56331272c5a4 395 Pfam PF12832 MFS_1 like family 7 363 6.9E-70 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain SmaCSM2_RS14035 9dbb1252acc67b5821af56331272c5a4 395 Gene3D G3DSA:1.20.1250.20 190 390 6.5E-23 T 28-03-2018 SmaCSM2_RS14035 9dbb1252acc67b5821af56331272c5a4 395 Gene3D G3DSA:1.20.1250.20 3 181 1.7E-8 T 28-03-2018 SmaCSM2_RS06240 d065e25d0600ac7f6f151798fe0865ae 132 Pfam PF00892 EamA-like transporter family 7 116 3.4E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06240 d065e25d0600ac7f6f151798fe0865ae 132 SUPERFAMILY SSF103481 31 120 2.09E-13 T 28-03-2018 SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 507 4.7E-20 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 SUPERFAMILY SSF52540 1 198 1.33E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 SUPERFAMILY SSF52540 367 507 1.33E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 SUPERFAMILY SSF52540 286 338 1.33E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 PIRSF PIRSF003128 1 553 2.9E-146 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 Gene3D G3DSA:3.40.50.300 1 526 3.4E-40 T 28-03-2018 SmaCSM2_RS08735 ad29b0266c5f1db5e5d97ddc7a785ac9 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 4.8E-147 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 13 227 1.9E-82 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 28 43 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 SUPERFAMILY SSF100950 13 237 3.77E-91 T 28-03-2018 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 SMART SM00882 15 227 1.1E-97 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 Pfam PF01144 Coenzyme A transferase 16 227 6.5E-83 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SmaCSM2_RS02805 3ef89e8c32270baac5db7be782181b08 244 Gene3D G3DSA:3.40.1080.10 5 244 1.4E-102 T 28-03-2018 SmaCSM2_RS14900 5d20a2e44c043dbf2698e430393d61c6 123 SUPERFAMILY SSF103196 8 120 2.27E-18 T 28-03-2018 SmaCSM2_RS14900 5d20a2e44c043dbf2698e430393d61c6 123 Pfam PF03259 Roadblock/LC7 domain 10 85 2.1E-12 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SmaCSM2_RS14900 5d20a2e44c043dbf2698e430393d61c6 123 Gene3D G3DSA:3.30.450.30 6 121 3.0E-22 T 28-03-2018 SmaCSM2_RS14900 5d20a2e44c043dbf2698e430393d61c6 123 SMART SM00960 7 97 4.9E-11 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SmaCSM2_RS21700 b9698e6abb8fc81b8314262afad84707 356 Pfam PF00248 Aldo/keto reductase family 18 324 1.1E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS21700 b9698e6abb8fc81b8314262afad84707 356 SUPERFAMILY SSF51430 6 325 5.63E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS21700 b9698e6abb8fc81b8314262afad84707 356 Gene3D G3DSA:3.20.20.100 4 331 8.1E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 197 566 1.2E-89 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Gene3D G3DSA:3.30.750.44 153 243 1.2E-21 T 28-03-2018 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 SMART SM00245 327 547 8.4E-51 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Gene3D G3DSA:2.30.42.10 244 343 4.8E-15 T 28-03-2018 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 SUPERFAMILY SSF52096 170 262 1.99E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 SUPERFAMILY SSF52096 357 552 1.99E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Gene3D G3DSA:3.90.226.10 347 704 2.2E-54 T 28-03-2018 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 SUPERFAMILY SSF50156 243 315 7.78E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 550 700 1.6E-39 T 28-03-2018 IPR020992 Tail specific protease, C-terminal SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 242 317 2.7E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 Pfam PF03572 Peptidase family S41 363 544 7.6E-53 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SmaCSM2_RS18315 b78d16f2f4f7ca054434f393a688eb74 725 SMART SM00228 244 322 5.6E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SmaCSM2_RS12555 2d35ad53ee2c4b563862407d65e8c429 382 Pfam PF00487 Fatty acid desaturase 73 340 1.1E-31 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SmaCSM2_RS21150 f6f5cba95eccc58d5bb337a1f9370832 337 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 333 1.1E-44 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SmaCSM2_RS21150 f6f5cba95eccc58d5bb337a1f9370832 337 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 326 9.0E-95 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SmaCSM2_RS14330 774ac962217e67a5842ce9ad6f358db4 150 SUPERFAMILY SSF53933 57 142 5.67E-32 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SmaCSM2_RS14330 774ac962217e67a5842ce9ad6f358db4 150 Gene3D G3DSA:3.10.450.30 54 146 7.8E-32 T 28-03-2018 SmaCSM2_RS14330 774ac962217e67a5842ce9ad6f358db4 150 Pfam PF00545 ribonuclease 60 140 2.7E-28 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SmaCSM2_RS11625 5c80a3a9acf3f0871aa1839915636179 379 Pfam PF13421 SPFH domain-Band 7 family 56 188 3.7E-8 T 28-03-2018 IPR033880 SPFH domain, YdjI-like SmaCSM2_RS07875 fdd35708c284e1aad149e50bd8a32dce 130 TIGRFAM TIGR00494 crcB: protein CrcB 8 124 8.4E-26 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SmaCSM2_RS07875 fdd35708c284e1aad149e50bd8a32dce 130 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 120 1.7E-21 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SmaCSM2_RS07875 fdd35708c284e1aad149e50bd8a32dce 130 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 7 126 18.411 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SmaCSM2_RS03425 827a7877511ba70cb9fd2a1e7bfabbc6 432 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 209 428 3.1E-76 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 SmaCSM2_RS03425 827a7877511ba70cb9fd2a1e7bfabbc6 432 Pfam PF07670 Nucleoside recognition 98 197 1.7E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 SmaCSM2_RS03425 827a7877511ba70cb9fd2a1e7bfabbc6 432 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 13 86 1.5E-23 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 SmaCSM2_RS13610 844dfd25d63e955127a2ed7d6e2b2457 195 Pfam PF02525 Flavodoxin-like fold 1 184 1.4E-47 T 28-03-2018 IPR003680 Flavodoxin-like fold SmaCSM2_RS13610 844dfd25d63e955127a2ed7d6e2b2457 195 SUPERFAMILY SSF52218 1 188 9.83E-52 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS13610 844dfd25d63e955127a2ed7d6e2b2457 195 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 188 30.292 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 SmaCSM2_RS13610 844dfd25d63e955127a2ed7d6e2b2457 195 Gene3D G3DSA:3.40.50.360 1 194 2.5E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain SmaCSM2_RS05785 98dbdb0b852d00b6a3af2145d175f2c6 398 Pfam PF07730 Histidine kinase 197 259 6.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SmaCSM2_RS05785 98dbdb0b852d00b6a3af2145d175f2c6 398 Gene3D G3DSA:3.30.565.10 261 385 3.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS05785 98dbdb0b852d00b6a3af2145d175f2c6 398 SUPERFAMILY SSF55874 276 382 2.74E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS09875 403587808b7031f1304398131a69a51b 260 Gene3D G3DSA:1.10.260.40 1 92 1.0E-16 T 28-03-2018 SmaCSM2_RS09875 403587808b7031f1304398131a69a51b 260 SUPERFAMILY SSF47413 33 84 8.0E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SmaCSM2_RS09875 403587808b7031f1304398131a69a51b 260 Pfam PF13560 Helix-turn-helix domain 10 87 1.0E-19 T 28-03-2018 SmaCSM2_RS09875 403587808b7031f1304398131a69a51b 260 SMART SM00530 14 85 6.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SmaCSM2_RS21155 fd31debaf03af82ee92acd49adb7eb6f 465 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 435 2.4E-152 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SmaCSM2_RS21155 fd31debaf03af82ee92acd49adb7eb6f 465 PIRSF PIRSF006446 1 457 3.7E-184 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SmaCSM2_RS08970 88f10d41e1a57d70c7adc147c38892f1 345 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 6 339 1.4E-105 T 28-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SmaCSM2_RS08970 88f10d41e1a57d70c7adc147c38892f1 345 SUPERFAMILY SSF55909 3 340 4.1E-113 T 28-03-2018 SmaCSM2_RS08970 88f10d41e1a57d70c7adc147c38892f1 345 Gene3D G3DSA:3.75.10.10 1 345 5.4E-118 T 28-03-2018 SmaCSM2_RS20350 402e7696ac0606c6be04fcda1db5186e 373 SUPERFAMILY SSF56349 63 351 1.53E-25 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS20350 402e7696ac0606c6be04fcda1db5186e 373 Gene3D G3DSA:1.10.150.130 54 174 2.2E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS20350 402e7696ac0606c6be04fcda1db5186e 373 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 64 136 1.8E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SmaCSM2_RS20350 402e7696ac0606c6be04fcda1db5186e 373 Gene3D G3DSA:1.10.443.10 175 356 1.9E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS20350 402e7696ac0606c6be04fcda1db5186e 373 Pfam PF00589 Phage integrase family 182 353 7.8E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS13600 5a45d2790b089f39fe1cec7513792d35 357 SUPERFAMILY SSF48403 213 298 5.59E-6 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS13600 5a45d2790b089f39fe1cec7513792d35 357 Gene3D G3DSA:1.25.40.20 212 317 3.4E-7 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SmaCSM2_RS13600 5a45d2790b089f39fe1cec7513792d35 357 Pfam PF14025 Protein of unknown function (DUF4241) 33 204 5.6E-34 T 28-03-2018 IPR025335 Protein of unknown function DUF4241 SmaCSM2_RS17480 382c79827a7ff663d8029d50969c715c 73 Gene3D G3DSA:1.20.5.400 2 72 2.1E-6 T 28-03-2018 SmaCSM2_RS17480 382c79827a7ff663d8029d50969c715c 73 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 9 73 4.0E-29 T 28-03-2018 IPR012662 Conserved hypothetical protein CHP02449 SmaCSM2_RS03325 d69efab710a278260122374e6d760006 308 SUPERFAMILY SSF53474 43 307 4.71E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03325 d69efab710a278260122374e6d760006 308 Gene3D G3DSA:3.40.50.1820 35 308 7.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS03325 d69efab710a278260122374e6d760006 308 Pfam PF12697 Alpha/beta hydrolase family 54 296 1.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS18865 30cf0a5cca8c4b0c86e0710c839c2144 103 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 12 33 7.5E-8 T 28-03-2018 IPR019626 Stress-induced protein, KGG, repeat SmaCSM2_RS17620 82ee15e43aab4bcd9375062f104d80a9 129 Pfam PF04343 Protein of unknown function, DUF488 23 120 6.1E-17 T 28-03-2018 IPR007438 Protein of unknown function DUF488 SmaCSM2_RS19755 cfa65437845c95a3ce28affed5217ff9 511 Pfam PF00361 Proton-conducting membrane transporter 129 422 6.5E-36 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS19755 cfa65437845c95a3ce28affed5217ff9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 163 187 3.9E-8 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS19755 cfa65437845c95a3ce28affed5217ff9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 381 407 3.9E-8 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS19755 cfa65437845c95a3ce28affed5217ff9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 236 260 3.9E-8 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS19755 cfa65437845c95a3ce28affed5217ff9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 133 152 3.9E-8 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS20200 1f80d6332bc47aeb41015fbdebe0b98c 191 SUPERFAMILY SSF53098 38 183 1.5E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS20200 1f80d6332bc47aeb41015fbdebe0b98c 191 Pfam PF00665 Integrase core domain 51 142 2.5E-7 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SmaCSM2_RS20200 1f80d6332bc47aeb41015fbdebe0b98c 191 Gene3D G3DSA:3.30.420.10 21 189 3.9E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06560 a7c468aaf96f2f440fe7d70318b95e59 151 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 151 6.4E-40 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 SmaCSM2_RS06560 a7c468aaf96f2f440fe7d70318b95e59 151 PIRSF PIRSF004638 1 151 7.8E-42 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 SmaCSM2_RS12940 c42911efe9215f125eeee04ef8cecc34 128 Pfam PF14534 Domain of unknown function (DUF4440) 17 118 1.6E-6 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SmaCSM2_RS12940 c42911efe9215f125eeee04ef8cecc34 128 Gene3D G3DSA:3.10.450.50 4 126 1.6E-31 T 28-03-2018 SmaCSM2_RS12940 c42911efe9215f125eeee04ef8cecc34 128 SUPERFAMILY SSF54427 6 124 1.14E-27 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS12940 c42911efe9215f125eeee04ef8cecc34 128 PIRSF PIRSF029394 1 128 1.6E-32 T 28-03-2018 IPR016918 Uncharacterised conserved protein UCP029394 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 Pfam PF00700 Bacterial flagellin C-terminal helical region 307 391 8.1E-28 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 9.5E-41 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 PRINTS PR00207 Flagellin signature 76 95 1.2E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 PRINTS PR00207 Flagellin signature 37 54 1.2E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 PRINTS PR00207 Flagellin signature 111 134 1.2E-26 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 Gene3D G3DSA:1.20.1330.10 193 364 1.9E-25 T 28-03-2018 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 Gene3D G3DSA:1.20.1330.10 40 191 6.5E-46 T 28-03-2018 SmaCSM2_RS10235 e6a8c678a52cd3cf97d18476ee01f0d5 392 SUPERFAMILY SSF64518 1 392 2.09E-101 T 28-03-2018 SmaCSM2_RS21130 5d5f62010e805baa22c35c1a284f0a9b 85 SUPERFAMILY SSF47336 1 83 2.49E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS21130 5d5f62010e805baa22c35c1a284f0a9b 85 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 14.595 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SmaCSM2_RS21130 5d5f62010e805baa22c35c1a284f0a9b 85 Pfam PF00550 Phosphopantetheine attachment site 8 74 2.3E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS21130 5d5f62010e805baa22c35c1a284f0a9b 85 Gene3D G3DSA:1.10.1200.10 1 82 7.7E-17 T 28-03-2018 SmaCSM2_RS11640 6c878178d2631562dbed59b56a42cfb0 298 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 183 193 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 SmaCSM2_RS11640 6c878178d2631562dbed59b56a42cfb0 298 Gene3D G3DSA:3.90.190.10 70 236 2.8E-19 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS11640 6c878178d2631562dbed59b56a42cfb0 298 Pfam PF13350 Tyrosine phosphatase family 52 294 1.4E-53 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SmaCSM2_RS11640 6c878178d2631562dbed59b56a42cfb0 298 SUPERFAMILY SSF52799 52 291 6.08E-43 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SmaCSM2_RS21135 96d944c8a97693d34f083bc47c24e275 85 Gene3D G3DSA:1.10.1200.10 2 85 5.1E-16 T 28-03-2018 SmaCSM2_RS21135 96d944c8a97693d34f083bc47c24e275 85 SUPERFAMILY SSF47336 2 83 4.84E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS21135 96d944c8a97693d34f083bc47c24e275 85 Pfam PF00550 Phosphopantetheine attachment site 9 62 1.5E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SmaCSM2_RS19485 440be53a85828bac45804158adc29dd8 119 Gene3D G3DSA:3.30.450.30 1 118 1.1E-20 T 28-03-2018 SmaCSM2_RS15490 34cc459b2062ce044c53c9de92ccbb80 160 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 136 7.2E-11 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SmaCSM2_RS15490 34cc459b2062ce044c53c9de92ccbb80 160 Gene3D G3DSA:3.10.50.40 1 160 3.0E-27 T 28-03-2018 SmaCSM2_RS15490 34cc459b2062ce044c53c9de92ccbb80 160 SUPERFAMILY SSF54534 2 140 5.11E-34 T 28-03-2018 SmaCSM2_RS08710 f2227dbcd3256e2655dace657066807f 85 Hamap MF_00460 Protein RnfH [rnfH]. 2 84 17.227 T 28-03-2018 IPR005346 RnfH protein SmaCSM2_RS08710 f2227dbcd3256e2655dace657066807f 85 Gene3D G3DSA:3.10.20.280 1 80 5.8E-21 T 28-03-2018 IPR005346 RnfH protein SmaCSM2_RS08710 f2227dbcd3256e2655dace657066807f 85 SUPERFAMILY SSF54285 1 71 5.79E-14 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SmaCSM2_RS08710 f2227dbcd3256e2655dace657066807f 85 Pfam PF03658 RnfH family Ubiquitin 2 79 6.6E-18 T 28-03-2018 IPR005346 RnfH protein SmaCSM2_RS12770 5070ec8e859935da2f1a1502e37bedab 234 Gene3D G3DSA:1.20.120.330 107 216 4.6E-5 T 28-03-2018 SmaCSM2_RS12770 5070ec8e859935da2f1a1502e37bedab 234 SUPERFAMILY SSF57997 136 218 9.81E-6 T 28-03-2018 SmaCSM2_RS12770 5070ec8e859935da2f1a1502e37bedab 234 Pfam PF11180 Protein of unknown function (DUF2968) 38 211 8.9E-65 T 28-03-2018 IPR021350 Protein of unknown function DUF2968 SmaCSM2_RS06955 c82ef44f04b2910961dedecc8b114430 109 Pfam PF11804 Protein of unknown function (DUF3325) 3 104 6.9E-31 T 28-03-2018 IPR021762 Protein of unknown function DUF3325 SmaCSM2_RS14740 c7e521357c7d4fca0bf91f779c9ecc1a 179 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 6 65 8.3E-30 T 28-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal SmaCSM2_RS14740 c7e521357c7d4fca0bf91f779c9ecc1a 179 Pfam PF05233 PHB accumulation regulatory domain 70 109 2.3E-18 T 28-03-2018 IPR007897 PHB accumulation regulatory SmaCSM2_RS14740 c7e521357c7d4fca0bf91f779c9ecc1a 179 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 5 111 1.2E-53 T 28-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 SmaCSM2_RS06435 9aadb720fc7e8aa46730036d0d1d55d4 73 SUPERFAMILY SSF55174 2 69 7.2E-21 T 28-03-2018 SmaCSM2_RS06435 9aadb720fc7e8aa46730036d0d1d55d4 73 Gene3D G3DSA:3.10.290.10 1 71 4.2E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SmaCSM2_RS06435 9aadb720fc7e8aa46730036d0d1d55d4 73 Pfam PF13275 S4 domain 7 69 4.7E-27 T 28-03-2018 SmaCSM2_RS00605 cece677a560b7223d26cfb9b76179bdd 152 Pfam PF03724 META domain 28 144 1.8E-11 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ SmaCSM2_RS01465 7a87504d8a07b088336e5eec1c992523 298 Pfam PF00005 ABC transporter 24 160 1.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS01465 7a87504d8a07b088336e5eec1c992523 298 SMART SM00382 33 209 7.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS01465 7a87504d8a07b088336e5eec1c992523 298 SUPERFAMILY SSF52540 9 221 3.2E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS01465 7a87504d8a07b088336e5eec1c992523 298 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS01465 7a87504d8a07b088336e5eec1c992523 298 Gene3D G3DSA:3.40.50.300 7 288 1.4E-53 T 28-03-2018 SmaCSM2_RS14485 b6ba0cf068d21e0ce7f59f63b60e73ae 62 Pfam PF04995 Heme exporter protein D (CcmD) 1 44 2.4E-9 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 SmaCSM2_RS06485 67c7e18d1621e209913eee3906c76b1d 519 Gene3D G3DSA:3.40.710.10 19 379 5.1E-82 T 28-03-2018 SmaCSM2_RS06485 67c7e18d1621e209913eee3906c76b1d 519 Pfam PF00144 Beta-lactamase 29 365 1.0E-70 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS06485 67c7e18d1621e209913eee3906c76b1d 519 Pfam PF11954 Domain of unknown function (DUF3471) 411 516 3.6E-34 T 28-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal SmaCSM2_RS06485 67c7e18d1621e209913eee3906c76b1d 519 SUPERFAMILY SSF56601 25 361 4.48E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 191 0.0052 T 28-03-2018 SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 2.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 260 5.9E-60 T 28-03-2018 SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 Gene3D G3DSA:3.40.50.720 17 261 1.9E-60 T 28-03-2018 SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 SUPERFAMILY SSF51735 17 260 1.74E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS18560 3868c200a677bbf1780227b9fc69749e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS11675 e8de2b655532ba05d688124f54974ce4 386 Pfam PF01551 Peptidase family M23 230 328 7.0E-16 T 28-03-2018 IPR016047 Peptidase M23 SmaCSM2_RS11675 e8de2b655532ba05d688124f54974ce4 386 Gene3D G3DSA:2.70.70.10 143 342 6.4E-23 T 28-03-2018 SmaCSM2_RS11675 e8de2b655532ba05d688124f54974ce4 386 SUPERFAMILY SSF51261 229 325 3.56E-18 T 28-03-2018 IPR011055 Duplicated hybrid motif SmaCSM2_RS19070 127a9beaefaeefe5504f998a7d4c04cf 157 Hamap MF_00598 Protein Smg [smg]. 5 157 30.574 T 28-03-2018 IPR007456 Smg SmaCSM2_RS19070 127a9beaefaeefe5504f998a7d4c04cf 157 Pfam PF04361 Protein of unknown function (DUF494) 5 157 2.5E-56 T 28-03-2018 IPR007456 Smg SmaCSM2_RS13270 3244fe219078ca8e563ccd12dce1d57b 453 PIRSF PIRSF006603 11 452 1.9E-80 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS13270 3244fe219078ca8e563ccd12dce1d57b 453 Pfam PF01554 MatE 254 414 8.8E-19 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS13270 3244fe219078ca8e563ccd12dce1d57b 453 Pfam PF01554 MatE 25 182 1.3E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS13270 3244fe219078ca8e563ccd12dce1d57b 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 426 5.5E-54 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS18670 97ec4fbaaad25cb9258c8c36a72fd6f2 177 Gene3D G3DSA:3.40.630.30 4 149 2.6E-17 T 28-03-2018 SmaCSM2_RS18670 97ec4fbaaad25cb9258c8c36a72fd6f2 177 Pfam PF13673 Acetyltransferase (GNAT) domain 62 156 7.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS18670 97ec4fbaaad25cb9258c8c36a72fd6f2 177 SUPERFAMILY SSF55729 38 149 5.15E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 Hamap MF_00124 Thymidine kinase [tdk]. 1 190 33.557 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 SUPERFAMILY SSF57716 143 194 1.71E-13 T 28-03-2018 SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 PIRSF PIRSF035805 1 199 5.3E-51 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 Gene3D G3DSA:3.40.50.300 1 142 1.0E-44 T 28-03-2018 SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 SUPERFAMILY SSF52540 1 142 1.1E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 Pfam PF00265 Thymidine kinase 2 185 4.0E-48 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SmaCSM2_RS00320 86eaeee0bbba2929828b5057d2a2a41a 206 Gene3D G3DSA:3.30.60.20 143 193 8.0E-13 T 28-03-2018 SmaCSM2_RS17155 9010f54f05c7907acbb27809c6b457e2 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 187 7.1E-32 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17155 9010f54f05c7907acbb27809c6b457e2 217 Gene3D G3DSA:3.40.50.1000 5 31 0.33 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17155 9010f54f05c7907acbb27809c6b457e2 217 SUPERFAMILY SSF56784 8 216 1.27E-47 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS17155 9010f54f05c7907acbb27809c6b457e2 217 Gene3D G3DSA:1.10.150.240 32 77 1.2E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SmaCSM2_RS17155 9010f54f05c7907acbb27809c6b457e2 217 Gene3D G3DSA:3.40.50.1000 78 217 1.4E-31 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS11005 3f5040a08ba25ec018298dfc872e90b0 372 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 3.6E-66 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS11005 3f5040a08ba25ec018298dfc872e90b0 372 SUPERFAMILY SSF51395 1 345 1.13E-104 T 28-03-2018 SmaCSM2_RS11005 3f5040a08ba25ec018298dfc872e90b0 372 Gene3D G3DSA:3.20.20.70 1 353 2.7E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS15660 6a24c4fd0109070430cc1553047e8b2a 150 Pfam PF14539 Domain of unknown function (DUF4442) 8 142 7.4E-18 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 SmaCSM2_RS15660 6a24c4fd0109070430cc1553047e8b2a 150 SUPERFAMILY SSF54637 4 143 9.16E-22 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS15660 6a24c4fd0109070430cc1553047e8b2a 150 Gene3D G3DSA:3.10.129.10 1 145 1.9E-19 T 28-03-2018 SmaCSM2_RS01470 cb49e3a22e9c51530574aa68587a2f02 258 PIRSF PIRSF006648 17 257 2.5E-20 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS01470 cb49e3a22e9c51530574aa68587a2f02 258 Pfam PF01061 ABC-2 type transporter 27 218 6.2E-13 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SmaCSM2_RS07960 09ca826e1155f0d8cdb700e90594b869 331 Pfam PF00296 Luciferase-like monooxygenase 18 295 3.5E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS07960 09ca826e1155f0d8cdb700e90594b869 331 SUPERFAMILY SSF51679 2 321 1.65E-81 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SmaCSM2_RS07960 09ca826e1155f0d8cdb700e90594b869 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 322 7.9E-134 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SmaCSM2_RS07960 09ca826e1155f0d8cdb700e90594b869 331 Gene3D G3DSA:3.20.20.30 1 328 1.2E-69 T 28-03-2018 SmaCSM2_RS04525 8786217ac83efc68dcc53319da69c02c 129 Gene3D G3DSA:3.10.450.50 9 126 5.1E-26 T 28-03-2018 SmaCSM2_RS04525 8786217ac83efc68dcc53319da69c02c 129 Pfam PF14534 Domain of unknown function (DUF4440) 17 119 1.6E-16 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SmaCSM2_RS04525 8786217ac83efc68dcc53319da69c02c 129 SUPERFAMILY SSF54427 13 126 8.04E-19 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS03350 d23d78139bf81dc1eff239cba19ef5c8 211 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 132 207 7.4E-12 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS03350 d23d78139bf81dc1eff239cba19ef5c8 211 Gene3D G3DSA:3.30.1150.10 73 211 1.5E-14 T 28-03-2018 SmaCSM2_RS03350 d23d78139bf81dc1eff239cba19ef5c8 211 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 131 209 9.4E-15 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS03350 d23d78139bf81dc1eff239cba19ef5c8 211 SUPERFAMILY SSF74653 127 187 3.27E-13 T 28-03-2018 SmaCSM2_RS02020 ca6da62713e312a80eeb3e735e9e1d2c 319 Pfam PF06258 Mitochondrial fission ELM1 16 316 8.4E-83 T 28-03-2018 IPR009367 Mitochondrial fission protein ELM1-like SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 Pfam PF00072 Response regulator receiver domain 5 117 9.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 SMART SM00448 3 117 1.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 3.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 Gene3D G3DSA:3.40.50.2300 2 127 4.7E-27 T 28-03-2018 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 SUPERFAMILY SSF52172 3 138 2.7E-24 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 Gene3D G3DSA:1.10.10.10 128 207 4.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 SUPERFAMILY SSF46894 133 205 1.63E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SmaCSM2_RS01605 30a711b5cf55bd1ff8c132f81c025b72 208 SMART SM00421 146 203 9.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SmaCSM2_RS10675 1216601bb82914122e788f93def1c245 103 Pfam PF10734 Protein of unknown function (DUF2523) 8 92 6.0E-8 T 28-03-2018 IPR019670 Protein of unkown function DUF2523 SmaCSM2_RS02030 dc6a5d900c6e2c3d11b23def5f822ec9 235 SUPERFAMILY SSF101874 64 230 4.71E-51 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS02030 dc6a5d900c6e2c3d11b23def5f822ec9 235 Pfam PF04264 YceI-like domain 66 228 2.2E-42 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS02030 dc6a5d900c6e2c3d11b23def5f822ec9 235 Gene3D G3DSA:2.40.128.110 64 232 2.7E-50 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS02030 dc6a5d900c6e2c3d11b23def5f822ec9 235 SMART SM00867 65 229 8.5E-68 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SmaCSM2_RS04195 57a1e39c184305f2f94ce4a15af64dc1 152 Pfam PF07486 Cell Wall Hydrolase 35 142 1.4E-17 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 SmaCSM2_RS21070 656e58c9fe86cd5923a0f5cfefd8aacd 151 PIRSF PIRSF020565 1 151 4.8E-47 T 28-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted SmaCSM2_RS21070 656e58c9fe86cd5923a0f5cfefd8aacd 151 SUPERFAMILY SSF54637 6 142 5.03E-25 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS21070 656e58c9fe86cd5923a0f5cfefd8aacd 151 Gene3D G3DSA:3.10.129.10 3 137 1.4E-24 T 28-03-2018 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 26 325 53.638 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Pfam PF00589 Phage integrase family 132 310 2.0E-43 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 SUPERFAMILY SSF47823 24 120 3.73E-30 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 28 109 1.8E-14 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 SUPERFAMILY SSF56349 127 323 2.91E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Gene3D G3DSA:1.10.443.10 135 319 3.0E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 29 324 1.2E-105 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 24 325 57.181 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 SmaCSM2_RS02920 4ac3e7d9ce029d147fa30d000febf2f2 325 Gene3D G3DSA:1.10.150.130 24 134 2.9E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SmaCSM2_RS16280 74d3e853f52322dde4e8bb11bf5c546b 190 Gene3D G3DSA:1.20.950.20 1 188 2.2E-35 T 28-03-2018 SmaCSM2_RS16280 74d3e853f52322dde4e8bb11bf5c546b 190 Pfam PF01292 Prokaryotic cytochrome b561 10 180 8.6E-30 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 SmaCSM2_RS16280 74d3e853f52322dde4e8bb11bf5c546b 190 SUPERFAMILY SSF81342 4 183 2.59E-37 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SmaCSM2_RS06045 496d4376ed8dd8bfe5e44606b9b719c7 264 Pfam PF01578 Cytochrome C assembly protein 41 257 4.5E-32 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SmaCSM2_RS19025 722a4e16e4d2bede7fca51185b08b470 352 PIRSF PIRSF028458 1 352 2.4E-159 T 28-03-2018 IPR016886 Predicted glycerophosphotransferase UCP028458 SmaCSM2_RS19025 722a4e16e4d2bede7fca51185b08b470 352 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 129 256 6.9E-7 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 SmaCSM2_RS19025 722a4e16e4d2bede7fca51185b08b470 352 Gene3D G3DSA:3.40.50.2000 207 272 2.4E-4 T 28-03-2018 SmaCSM2_RS19025 722a4e16e4d2bede7fca51185b08b470 352 SUPERFAMILY SSF53756 8 319 3.85E-29 T 28-03-2018 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 Gene3D G3DSA:1.20.140.10 281 456 9.3E-34 T 28-03-2018 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 SUPERFAMILY SSF47203 295 448 1.77E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 Gene3D G3DSA:2.40.110.10 186 280 6.7E-18 T 28-03-2018 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 445 2.4E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 SUPERFAMILY SSF56645 74 299 1.69E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SmaCSM2_RS15855 77fb486d6ed8bb83fb662c2bf9ce2acc 545 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 186 278 4.4E-12 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SmaCSM2_RS17070 3c55f73a0915898f378a610c204e2bc9 473 SUPERFAMILY SSF52025 110 242 6.02E-5 T 28-03-2018 SmaCSM2_RS17070 3c55f73a0915898f378a610c204e2bc9 473 Gene3D G3DSA:3.40.630.10 42 463 1.3E-49 T 28-03-2018 SmaCSM2_RS17070 3c55f73a0915898f378a610c204e2bc9 473 SUPERFAMILY SSF53187 251 457 5.74E-52 T 28-03-2018 SmaCSM2_RS17070 3c55f73a0915898f378a610c204e2bc9 473 SUPERFAMILY SSF53187 47 97 5.74E-52 T 28-03-2018 SmaCSM2_RS17070 3c55f73a0915898f378a610c204e2bc9 473 Pfam PF04389 Peptidase family M28 259 445 2.8E-24 T 28-03-2018 IPR007484 Peptidase M28 SmaCSM2_RS07015 453c544908714ce55e0cad98bacbd580 529 Pfam PF05231 MASE1 19 289 4.4E-19 T 28-03-2018 IPR007895 MASE1 SmaCSM2_RS11525 f8b2f5f420febb11400f6544c8814886 180 Gene3D G3DSA:3.90.1590.10 3 159 9.4E-20 T 28-03-2018 SmaCSM2_RS11525 f8b2f5f420febb11400f6544c8814886 180 SUPERFAMILY SSF51316 10 150 3.45E-13 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 6.2E-39 T 28-03-2018 SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 Gene3D G3DSA:3.40.50.10090 1 48 7.0E-7 T 28-03-2018 SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 SUPERFAMILY SSF51735 4 256 5.37E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS17785 7dbee21536b6041bf404480c30ecfe38 257 Gene3D G3DSA:3.40.50.720 49 257 2.0E-40 T 28-03-2018 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 14 352 38.98 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 Pfam PF01008 Initiation factor 2 subunit family 57 340 9.2E-79 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 SUPERFAMILY SSF100950 12 343 1.85E-114 T 28-03-2018 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 Gene3D G3DSA:3.40.50.10470 148 350 2.1E-66 T 28-03-2018 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 Gene3D G3DSA:1.20.120.420 11 147 3.3E-45 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 17 340 1.0E-137 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SmaCSM2_RS13850 0801e972f55a4e0f7998c705249cce02 354 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 340 3.1E-114 T 28-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SmaCSM2_RS02695 ff65ad7db43f0cc1a40408ba71393767 430 Pfam PF01757 Acyltransferase family 16 398 1.6E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SmaCSM2_RS09685 3bdc826a55404a2c1c515978549bf941 475 PIRSF PIRSF006060 10 475 3.8E-96 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS09685 3bdc826a55404a2c1c515978549bf941 475 Pfam PF13520 Amino acid permease 27 440 1.7E-62 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SmaCSM2_RS14790 865420bdb4c025f4a58aa9b544a40a1a 298 Pfam PF01435 Peptidase family M48 120 281 1.8E-33 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SmaCSM2_RS14790 865420bdb4c025f4a58aa9b544a40a1a 298 Gene3D G3DSA:3.30.2010.10 79 186 6.2E-23 T 28-03-2018 SmaCSM2_RS07025 b2da0b87d0d9d72f0f0aba93de948dc4 425 Gene3D G3DSA:3.50.50.60 17 411 4.3E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07025 b2da0b87d0d9d72f0f0aba93de948dc4 425 SUPERFAMILY SSF51905 29 252 4.86E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07025 b2da0b87d0d9d72f0f0aba93de948dc4 425 SUPERFAMILY SSF51905 344 416 4.86E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS07025 b2da0b87d0d9d72f0f0aba93de948dc4 425 Pfam PF01266 FAD dependent oxidoreductase 30 380 2.4E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SmaCSM2_RS16060 64d6035ea764b381418dcaaaf1cce7de 408 Gene3D G3DSA:1.20.1250.20 2 196 1.6E-28 T 28-03-2018 SmaCSM2_RS16060 64d6035ea764b381418dcaaaf1cce7de 408 SUPERFAMILY SSF103473 9 398 3.14E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS16060 64d6035ea764b381418dcaaaf1cce7de 408 Pfam PF07690 Major Facilitator Superfamily 19 355 4.0E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS16060 64d6035ea764b381418dcaaaf1cce7de 408 Gene3D G3DSA:1.20.1250.20 205 406 7.6E-17 T 28-03-2018 SmaCSM2_RS16060 64d6035ea764b381418dcaaaf1cce7de 408 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 370 3.5E-68 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 SUPERFAMILY SSF47090 688 759 1.96E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 SUPERFAMILY SSF47090 302 372 3.66E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Gene3D G3DSA:1.10.101.10 300 374 1.3E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Gene3D G3DSA:1.10.101.10 681 764 4.6E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Gene3D G3DSA:1.10.101.10 375 443 2.7E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Pfam PF01471 Putative peptidoglycan binding domain 376 432 1.5E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Pfam PF01471 Putative peptidoglycan binding domain 698 758 7.2E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 Pfam PF01471 Putative peptidoglycan binding domain 311 371 2.7E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS01300 da28ad90451fe6967332a744ddfe5539 914 SUPERFAMILY SSF47090 373 435 1.07E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like SmaCSM2_RS17515 9dfae557d70b92a98919a9479cd27507 281 Gene3D G3DSA:1.25.40.10 14 274 3.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS17515 9dfae557d70b92a98919a9479cd27507 281 SUPERFAMILY SSF48452 195 266 2.11E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS17515 9dfae557d70b92a98919a9479cd27507 281 Pfam PF13371 Tetratricopeptide repeat 199 270 4.2E-15 T 28-03-2018 SmaCSM2_RS17515 9dfae557d70b92a98919a9479cd27507 281 Pfam PF13369 Transglutaminase-like superfamily 45 197 2.1E-46 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SmaCSM2_RS19775 c5035675a3a928b15f0cf6c6f844e2d4 321 Pfam PF01699 Sodium/calcium exchanger protein 5 144 2.5E-18 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SmaCSM2_RS19775 c5035675a3a928b15f0cf6c6f844e2d4 321 Pfam PF01699 Sodium/calcium exchanger protein 176 311 5.1E-19 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SmaCSM2_RS16010 d71db9f5bdca682277d480696dd2bad7 74 Pfam PF04328 Selenoprotein, putative 14 74 1.1E-25 T 28-03-2018 IPR007423 Selenoprotein, putative SmaCSM2_RS16685 c55acd48504db53facf06e59a242a931 142 TIGRFAM TIGR02801 tolR: protein TolR 14 140 3.2E-42 T 28-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 SmaCSM2_RS16685 c55acd48504db53facf06e59a242a931 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 140 1.3E-27 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS02270 39fd0910c97b4f15313a0b9c54182304 118 PIRSF PIRSF007028 1 118 2.5E-48 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 SmaCSM2_RS02270 39fd0910c97b4f15313a0b9c54182304 118 Pfam PF07237 Protein of unknown function (DUF1428) 3 103 4.7E-40 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 SmaCSM2_RS02270 39fd0910c97b4f15313a0b9c54182304 118 Gene3D G3DSA:3.30.70.100 1 118 1.8E-49 T 28-03-2018 SmaCSM2_RS02270 39fd0910c97b4f15313a0b9c54182304 118 SUPERFAMILY SSF54909 1 117 1.61E-44 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SmaCSM2_RS17315 06c5d4849a57caf4ebf9b9141d551f80 235 SUPERFAMILY SSF49354 19 126 5.23E-8 T 28-03-2018 IPR008962 PapD-like SmaCSM2_RS17315 06c5d4849a57caf4ebf9b9141d551f80 235 Gene3D G3DSA:2.60.40.10 22 152 2.4E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS07855 177a1eba1aae201416dc5fd9dc7615c1 358 Gene3D G3DSA:3.40.50.1820 34 355 2.3E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS07855 177a1eba1aae201416dc5fd9dc7615c1 358 SUPERFAMILY SSF53474 39 156 1.18E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS07855 177a1eba1aae201416dc5fd9dc7615c1 358 SUPERFAMILY SSF53474 272 348 1.18E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05010 bfa21cac1d4b2edac579a3e40035420f 149 Gene3D G3DSA:3.40.630.30 35 135 4.7E-18 T 28-03-2018 SmaCSM2_RS05010 bfa21cac1d4b2edac579a3e40035420f 149 SUPERFAMILY SSF55729 1 135 5.4E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05010 bfa21cac1d4b2edac579a3e40035420f 149 Pfam PF00583 Acetyltransferase (GNAT) family 37 127 7.0E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS05010 bfa21cac1d4b2edac579a3e40035420f 149 Gene3D G3DSA:1.10.287.900 2 34 1.7E-13 T 28-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 SmaCSM2_RS15460 a250eec918277158b99121c356d1d4b0 224 SUPERFAMILY SSF144091 4 206 1.7E-44 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS15460 a250eec918277158b99121c356d1d4b0 224 Pfam PF01694 Rhomboid family 53 202 1.9E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS15460 a250eec918277158b99121c356d1d4b0 224 Gene3D G3DSA:1.20.1540.10 3 202 3.7E-48 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS02620 ef21b07755de70e350d2385a9f0cdacd 329 Gene3D G3DSA:3.90.850.10 27 311 3.3E-50 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS02620 ef21b07755de70e350d2385a9f0cdacd 329 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 82 323 1.3E-33 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS02620 ef21b07755de70e350d2385a9f0cdacd 329 SUPERFAMILY SSF56529 77 323 2.88E-52 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SmaCSM2_RS10290 8d50a4f3e251878e42d44bcae2cea598 227 Pfam PF13861 FlgD Tudor-like domain 90 223 4.4E-15 T 28-03-2018 IPR025963 FlgD Tudor-like domain SmaCSM2_RS10290 8d50a4f3e251878e42d44bcae2cea598 227 Pfam PF13860 FlgD Ig-like domain 114 180 1.8E-15 T 28-03-2018 IPR025965 FlgD Ig-like domain SmaCSM2_RS10290 8d50a4f3e251878e42d44bcae2cea598 227 Pfam PF03963 Flagellar hook capping protein - N-terminal region 16 81 2.1E-24 T 28-03-2018 IPR005648 Flagellar hook capping protein SmaCSM2_RS10290 8d50a4f3e251878e42d44bcae2cea598 227 Gene3D G3DSA:2.60.40.10 85 199 4.1E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS09060 cdbe73c9c8c7d5e34e9d2b94a3b4086b 212 Pfam PF09976 Tetratricopeptide repeat-like domain 17 200 7.0E-38 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 SmaCSM2_RS09060 cdbe73c9c8c7d5e34e9d2b94a3b4086b 212 Gene3D G3DSA:1.25.40.10 38 193 8.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09060 cdbe73c9c8c7d5e34e9d2b94a3b4086b 212 PIRSF PIRSF006170 3 207 1.9E-42 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 SmaCSM2_RS09060 cdbe73c9c8c7d5e34e9d2b94a3b4086b 212 SUPERFAMILY SSF48452 93 185 7.59E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS19060 66e945eb3bf1885bc46ae8f80850346c 376 SUPERFAMILY SSF54106 31 79 3.79E-8 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS19060 66e945eb3bf1885bc46ae8f80850346c 376 Gene3D G3DSA:3.10.350.10 27 81 3.9E-17 T 28-03-2018 SmaCSM2_RS19060 66e945eb3bf1885bc46ae8f80850346c 376 SMART SM00257 32 80 1.6E-7 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS19060 66e945eb3bf1885bc46ae8f80850346c 376 Pfam PF01476 LysM domain 33 78 3.2E-14 T 28-03-2018 IPR018392 LysM domain SmaCSM2_RS10215 b9a86b56cd9cfa931864b80dfbdf5e9e 192 Pfam PF16823 Atypical PilZ domain, cyclic di-GMP receptor 48 190 2.3E-59 T 28-03-2018 IPR031800 Cyclic di-GMP receptor, atypical PilZ domain SmaCSM2_RS10215 b9a86b56cd9cfa931864b80dfbdf5e9e 192 Gene3D G3DSA:2.40.10.220 58 192 5.6E-4 T 28-03-2018 SmaCSM2_RS12090 b02e0597da0739bf65c4e6672814a01a 221 Gene3D G3DSA:3.30.1150.10 123 212 1.3E-10 T 28-03-2018 SmaCSM2_RS12090 b02e0597da0739bf65c4e6672814a01a 221 SUPERFAMILY SSF74653 49 62 2.35E-8 T 28-03-2018 SmaCSM2_RS12090 b02e0597da0739bf65c4e6672814a01a 221 SUPERFAMILY SSF74653 123 206 2.35E-8 T 28-03-2018 SmaCSM2_RS12090 b02e0597da0739bf65c4e6672814a01a 221 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 160 202 2.7E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS12090 b02e0597da0739bf65c4e6672814a01a 221 Pfam PF13103 TonB C terminal 155 205 1.0E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS18165 93146ea1954ca1d50e72271f1bc38797 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 134 1.8E-23 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS10085 c2ee729afccc49b9f976ec92877c7f77 126 Gene3D G3DSA:3.40.50.2300 1 126 1.5E-37 T 28-03-2018 SmaCSM2_RS10085 c2ee729afccc49b9f976ec92877c7f77 126 SMART SM00448 1 115 1.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10085 c2ee729afccc49b9f976ec92877c7f77 126 Pfam PF00072 Response regulator receiver domain 3 115 7.7E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS10085 c2ee729afccc49b9f976ec92877c7f77 126 SUPERFAMILY SSF52172 1 122 2.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS15945 345b04f7aa27310275b8eae7a2053cc6 127 Pfam PF16137 Domain of unknown function (DUF4845) 31 115 1.1E-27 T 28-03-2018 IPR032314 Protein of unknown function DUF4845 SmaCSM2_RS11165 54acb95fdcb2ed985f3f406d311aa890 208 SUPERFAMILY SSF53448 13 195 3.83E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS11165 54acb95fdcb2ed985f3f406d311aa890 208 Gene3D G3DSA:3.90.550.10 9 201 2.8E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS11165 54acb95fdcb2ed985f3f406d311aa890 208 Pfam PF12804 MobA-like NTP transferase domain 14 170 1.1E-27 T 28-03-2018 IPR025877 MobA-like NTP transferase SmaCSM2_RS19960 c04b8920155b19c0cf8619d1ddce31df 144 Pfam PF12120 Rifampin ADP-ribosyl transferase 22 120 4.0E-49 T 28-03-2018 IPR021975 DNA/RNA tunnel of bacterial DNA dependent RNA polymerase SmaCSM2_RS12965 ff52a10e8f09b60e6b3ce51eec714529 234 SUPERFAMILY SSF46689 128 178 5.61E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS12965 ff52a10e8f09b60e6b3ce51eec714529 234 SMART SM00342 145 227 3.8E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12965 ff52a10e8f09b60e6b3ce51eec714529 234 Gene3D G3DSA:1.10.10.60 184 226 2.0E-4 T 28-03-2018 SmaCSM2_RS12965 ff52a10e8f09b60e6b3ce51eec714529 234 Pfam PF12833 Helix-turn-helix domain 151 221 1.0E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SmaCSM2_RS12965 ff52a10e8f09b60e6b3ce51eec714529 234 Gene3D G3DSA:1.10.10.60 127 183 5.7E-9 T 28-03-2018 SmaCSM2_RS17560 896f0cb3056b3683d09fae8fc135f93b 330 Gene3D G3DSA:3.40.190.10 1 269 1.6E-4 T 28-03-2018 SmaCSM2_RS17560 896f0cb3056b3683d09fae8fc135f93b 330 Pfam PF12889 Protein of unknown function (DUF3829) 49 329 9.5E-86 T 28-03-2018 IPR024291 Protein of unknown function DUF3829 SmaCSM2_RS03005 8b34c5cb32bc97823f1acb5d9ff1ed1e 262 ProDom PD046566 PATHWAY N GENERAL SECRETION PRECURSOR SIGNAL MEMBRANE XPSN TRANSMEMBRANE INNER 1 169 6.0E-28 T 28-03-2018 SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 Gene3D G3DSA:2.150.10.10 1 134 1.1E-15 T 28-03-2018 SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 Pfam PF06594 Haemolysin-type calcium binding protein related domain 92 125 2.1E-6 T 28-03-2018 IPR010566 Haemolysin-type calcium binding-related SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 SUPERFAMILY SSF51120 2 126 1.01E-15 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 PRINTS PR00313 NodO calcium binding signature 32 41 2.5E-5 T 28-03-2018 SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 PRINTS PR00313 NodO calcium binding signature 3 11 2.5E-5 T 28-03-2018 SmaCSM2_RS16990 4700ff077dbcf10aefd7cef9f3b8c1f9 166 PRINTS PR00313 NodO calcium binding signature 12 20 2.5E-5 T 28-03-2018 SmaCSM2_RS17940 6cc973c95e020116a8aea5d296f9d955 205 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 188 1.1E-22 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS17940 6cc973c95e020116a8aea5d296f9d955 205 SUPERFAMILY SSF52266 3 195 3.97E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SmaCSM2_RS17940 6cc973c95e020116a8aea5d296f9d955 205 Gene3D G3DSA:3.40.50.1110 3 202 1.5E-28 T 28-03-2018 SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 220 4.7E-48 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 Gene3D G3DSA:3.30.390.50 224 314 3.8E-16 T 28-03-2018 SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 294 3.0E-8 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 SMART SM01092 226 314 1.1E-17 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 SUPERFAMILY SSF56176 2 219 4.58E-55 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 SUPERFAMILY SSF55447 223 312 7.33E-19 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 Gene3D G3DSA:3.30.43.10 1 51 7.1E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SmaCSM2_RS11180 49690d5ca7197ad0833ec047bd60eb2f 316 Gene3D G3DSA:3.30.465.10 54 221 3.5E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS19230 4f3d63c45f154eb5b54af4e5010f80f2 596 Pfam PF04231 Endonuclease I 325 577 2.8E-36 T 28-03-2018 IPR007346 Endonuclease I GO:0004518 SmaCSM2_RS19230 4f3d63c45f154eb5b54af4e5010f80f2 596 Pfam PF13205 Bacterial Ig-like domain 197 296 5.5E-13 T 28-03-2018 IPR032812 SbsA, Ig-like domain SmaCSM2_RS19230 4f3d63c45f154eb5b54af4e5010f80f2 596 SUPERFAMILY SSF54060 539 577 1.53E-40 T 28-03-2018 SmaCSM2_RS19230 4f3d63c45f154eb5b54af4e5010f80f2 596 SUPERFAMILY SSF54060 319 510 1.53E-40 T 28-03-2018 SmaCSM2_RS19230 4f3d63c45f154eb5b54af4e5010f80f2 596 Gene3D G3DSA:2.60.40.1260 19 128 1.7E-4 T 28-03-2018 IPR001322 Lamin Tail Domain SmaCSM2_RS15825 d529c66cc7eb8336e1f6837e45db97ba 358 Pfam PF08668 HDOD domain 96 282 3.4E-27 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD SmaCSM2_RS15825 d529c66cc7eb8336e1f6837e45db97ba 358 Gene3D G3DSA:1.10.3210.10 77 323 9.8E-22 T 28-03-2018 SmaCSM2_RS15825 d529c66cc7eb8336e1f6837e45db97ba 358 SUPERFAMILY SSF109604 87 324 1.63E-38 T 28-03-2018 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 SUPERFAMILY SSF53383 28 468 4.81E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 21 470 47.348 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 276 313 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 Gene3D G3DSA:3.90.1150.10 292 472 2.6E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 Gene3D G3DSA:3.90.1150.10 205 291 0.032 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 33 467 3.9E-165 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 Gene3D G3DSA:3.90.1150.10 15 199 3.1E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 Pfam PF00202 Aminotransferase class-III 48 463 1.6E-114 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS16455 4177a9774656f7dedcedf836339e4677 474 PIRSF PIRSF000521 43 440 1.6E-26 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SmaCSM2_RS20855 de52dfca78cc7f2a60a44c76e7b706de 206 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 200 87.636 T 28-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria SmaCSM2_RS20855 de52dfca78cc7f2a60a44c76e7b706de 206 Pfam PF03350 Uncharacterized protein family, UPF0114 15 131 4.0E-41 T 28-03-2018 IPR005134 Uncharacterised protein family UPF0114 SmaCSM2_RS20855 de52dfca78cc7f2a60a44c76e7b706de 206 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 12 200 1.4E-56 T 28-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria SmaCSM2_RS01240 65182e5ddcfc657878b402d320c708d1 85 Pfam PF08809 Phage related hypothetical protein (DUF1799) 4 82 1.5E-27 T 28-03-2018 IPR014915 Bacteriophage TLS, TfmB SmaCSM2_RS06550 fc3aa7f0eb8e6da602130956014416e4 435 PIRSF PIRSF020818 1 425 7.8E-194 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase SmaCSM2_RS06550 fc3aa7f0eb8e6da602130956014416e4 435 SUPERFAMILY SSF53474 108 409 1.1E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS06550 fc3aa7f0eb8e6da602130956014416e4 435 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 411 1.9E-189 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase SmaCSM2_RS06550 fc3aa7f0eb8e6da602130956014416e4 435 Pfam PF06850 PHB de-polymerase C-terminus 211 411 5.3E-96 T 28-03-2018 IPR009656 PHB de-polymerase, C-terminal SmaCSM2_RS06550 fc3aa7f0eb8e6da602130956014416e4 435 Gene3D G3DSA:3.40.50.1820 99 410 1.6E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 269 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 155 174 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 459 476 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 282 301 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 137 155 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 66 91 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 435 450 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 422 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 398 1.0E-43 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 SUPERFAMILY SSF56235 33 572 7.33E-178 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 45 564 8.4E-119 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS17735 754c43de3dcdf81b2046405775df8099 572 Pfam PF01019 Gamma-glutamyltranspeptidase 59 567 9.0E-162 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SmaCSM2_RS14975 207e6deabdbe56cb20ba26b55fa7fa5a 171 Gene3D G3DSA:2.60.40.20 60 89 0.43 T 28-03-2018 SmaCSM2_RS14975 207e6deabdbe56cb20ba26b55fa7fa5a 171 Pfam PF11218 Protein of unknown function (DUF3011) 36 168 8.0E-37 T 28-03-2018 IPR021381 Protein of unknown function DUF3011 SmaCSM2_RS00505 b2865f5b6cc242f61c719b8c78c6789f 298 SUPERFAMILY SSF53300 83 210 1.45E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS00505 b2865f5b6cc242f61c719b8c78c6789f 298 Pfam PF01882 Protein of unknown function DUF58 44 132 4.9E-20 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SmaCSM2_RS00505 b2865f5b6cc242f61c719b8c78c6789f 298 Gene3D G3DSA:3.40.50.410 56 222 1.1E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS02370 200b9d5472960de569da233a6fb9abc5 549 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 545 6.0E-122 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SmaCSM2_RS02370 200b9d5472960de569da233a6fb9abc5 549 PRINTS PR01084 Na+/H+ exchanger signature 69 83 3.4E-6 T 28-03-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 SmaCSM2_RS02370 200b9d5472960de569da233a6fb9abc5 549 PRINTS PR01084 Na+/H+ exchanger signature 119 129 3.4E-6 T 28-03-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 SmaCSM2_RS02370 200b9d5472960de569da233a6fb9abc5 549 PRINTS PR01084 Na+/H+ exchanger signature 55 66 3.4E-6 T 28-03-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 SmaCSM2_RS02370 200b9d5472960de569da233a6fb9abc5 549 Pfam PF00999 Sodium/hydrogen exchanger family 10 420 1.2E-62 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS21730 2b7111f8f3049b6e58ba1ee8f4697d60 256 SUPERFAMILY SSF144091 23 197 1.7E-20 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS21730 2b7111f8f3049b6e58ba1ee8f4697d60 256 Gene3D G3DSA:1.20.1540.10 23 197 1.9E-14 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS21730 2b7111f8f3049b6e58ba1ee8f4697d60 256 Pfam PF01694 Rhomboid family 63 196 1.6E-14 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 Gene3D G3DSA:3.40.50.300 8 236 5.8E-57 T 28-03-2018 SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 SUPERFAMILY SSF52540 11 232 5.84E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 Pfam PF00005 ABC transporter 32 179 2.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 SMART SM00382 40 228 1.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS08470 e2fbf91d54eb7c8169c5384489d2c7dd 237 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 11 230 4.7E-101 T 28-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 SMART SM00382 29 216 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 SUPERFAMILY SSF52540 3 225 5.33E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 Gene3D G3DSA:3.40.50.300 1 228 1.8E-62 T 28-03-2018 SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 4 216 5.1E-82 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SmaCSM2_RS19440 375b62147d46fc832c6591ef495cb026 228 Pfam PF00005 ABC transporter 20 167 3.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SmaCSM2_RS20130 3e5ffa63551a827e55d42bca950beffa 371 SUPERFAMILY SSF56601 32 353 5.12E-81 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS20130 3e5ffa63551a827e55d42bca950beffa 371 Gene3D G3DSA:3.40.710.10 13 369 2.4E-84 T 28-03-2018 SmaCSM2_RS20130 3e5ffa63551a827e55d42bca950beffa 371 Pfam PF00144 Beta-lactamase 37 356 4.8E-71 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 105 131 9.3E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 156 184 9.3E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 87 105 9.3E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 10 37 9.3E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 11 228 6.2E-68 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 Pfam PF00902 Sec-independent protein translocase protein (TatC) 13 223 4.2E-67 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 ProSitePatterns PS01218 TatC family signature. 156 175 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site SmaCSM2_RS21455 bc7bec4fd03a78910a91e57c5624f65a 249 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 246 18.396 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SmaCSM2_RS03035 178bbb8afa293cd2bee6ce24debe8643 179 Gene3D G3DSA:2.60.40.1090 24 179 3.5E-31 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 SmaCSM2_RS03035 178bbb8afa293cd2bee6ce24debe8643 179 SUPERFAMILY SSF49401 25 179 1.09E-27 T 28-03-2018 IPR008966 Adhesion domain SmaCSM2_RS03035 178bbb8afa293cd2bee6ce24debe8643 179 Pfam PF16970 Type-1 fimbrial protein, A 51 179 4.1E-24 T 28-03-2018 SmaCSM2_RS04940 50ff368a8689820f05a16479e97bccb5 673 SUPERFAMILY SSF53474 511 643 7.09E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS04940 50ff368a8689820f05a16479e97bccb5 673 SUPERFAMILY SSF53474 379 476 7.09E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS04940 50ff368a8689820f05a16479e97bccb5 673 Gene3D G3DSA:3.40.50.1820 373 666 1.9E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS01570 475268441c33868fd18c38d45dbab836 397 Gene3D G3DSA:1.20.1250.20 2 194 2.4E-23 T 28-03-2018 SmaCSM2_RS01570 475268441c33868fd18c38d45dbab836 397 SUPERFAMILY SSF103473 5 387 5.75E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS01570 475268441c33868fd18c38d45dbab836 397 Pfam PF07690 Major Facilitator Superfamily 19 294 2.6E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS01570 475268441c33868fd18c38d45dbab836 397 Gene3D G3DSA:1.20.1250.20 196 392 7.1E-13 T 28-03-2018 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 Pfam PF02911 Formyl transferase, C-terminal domain 203 299 1.5E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 SUPERFAMILY SSF50486 204 302 2.75E-30 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 Gene3D G3DSA:3.10.25.10 206 306 1.1E-27 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 Gene3D G3DSA:3.40.50.170 1 205 4.9E-68 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 Pfam PF00551 Formyl transferase 1 176 1.2E-43 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 131 154 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 SUPERFAMILY SSF53328 1 206 6.67E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 36.502 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SmaCSM2_RS19050 79a181ed804ebf54dbd907db268d3872 307 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 302 5.9E-93 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SmaCSM2_RS18220 eeffeceba67e61684dd47116118f2897 342 SUPERFAMILY SSF53697 11 340 1.21E-74 T 28-03-2018 SmaCSM2_RS18220 eeffeceba67e61684dd47116118f2897 342 Gene3D G3DSA:3.40.50.10490 8 195 6.7E-35 T 28-03-2018 SmaCSM2_RS18220 eeffeceba67e61684dd47116118f2897 342 Gene3D G3DSA:3.40.50.10490 199 342 7.5E-31 T 28-03-2018 SmaCSM2_RS18220 eeffeceba67e61684dd47116118f2897 342 Pfam PF01380 SIS domain 204 286 6.5E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS18220 eeffeceba67e61684dd47116118f2897 342 Pfam PF01380 SIS domain 49 170 1.4E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SmaCSM2_RS06705 e62991f5b018fb3f203fadd27fbf49a8 121 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 111 1.4E-27 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR SmaCSM2_RS06705 e62991f5b018fb3f203fadd27fbf49a8 121 Gene3D G3DSA:3.40.30.10 1 116 1.1E-32 T 28-03-2018 SmaCSM2_RS06705 e62991f5b018fb3f203fadd27fbf49a8 121 Pfam PF03960 ArsC family 7 114 1.1E-13 T 28-03-2018 IPR006660 Arsenate reductase-like SmaCSM2_RS06705 e62991f5b018fb3f203fadd27fbf49a8 121 SUPERFAMILY SSF52833 3 115 2.02E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS00240 fb6f47bc96dbe55ed9a4974aade72370 196 Gene3D G3DSA:2.60.120.10 12 194 1.1E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SmaCSM2_RS00240 fb6f47bc96dbe55ed9a4974aade72370 196 Pfam PF05995 Cysteine dioxygenase type I 62 177 3.4E-11 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SmaCSM2_RS00240 fb6f47bc96dbe55ed9a4974aade72370 196 SUPERFAMILY SSF51182 16 185 8.64E-31 T 28-03-2018 IPR011051 RmlC-like cupin domain SmaCSM2_RS10485 643a7da631f9234444fbedbe77c5fc6a 348 Pfam PF01497 Periplasmic binding protein 91 321 6.4E-18 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SmaCSM2_RS10485 643a7da631f9234444fbedbe77c5fc6a 348 Gene3D G3DSA:3.40.50.1980 87 190 2.4E-7 T 28-03-2018 SmaCSM2_RS10485 643a7da631f9234444fbedbe77c5fc6a 348 Gene3D G3DSA:3.40.50.1980 191 348 1.0E-26 T 28-03-2018 SmaCSM2_RS10485 643a7da631f9234444fbedbe77c5fc6a 348 SUPERFAMILY SSF53807 90 342 2.83E-31 T 28-03-2018 SmaCSM2_RS09175 f683afd43a1fdbdb958e036e4a801fc6 125 Pfam PF13788 Domain of unknown function (DUF4180) 11 118 1.1E-31 T 28-03-2018 IPR025438 Domain of unknown function DUF4180 SmaCSM2_RS07225 d3f1745ace3a9c5b8a30865cca08b0be 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 34 1.9E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07225 d3f1745ace3a9c5b8a30865cca08b0be 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 33 2.3E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site SmaCSM2_RS07225 d3f1745ace3a9c5b8a30865cca08b0be 165 Gene3D G3DSA:3.30.700.10 16 158 3.2E-5 T 28-03-2018 SmaCSM2_RS07225 d3f1745ace3a9c5b8a30865cca08b0be 165 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 13 143 3.9E-27 T 28-03-2018 IPR013362 Pilus modification type IV, PilV SmaCSM2_RS19435 a90e5c836d87bf947593c34bc10919fb 315 PIRSF PIRSF003097 19 309 5.9E-52 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SmaCSM2_RS08660 68b186c4913bcd9746e8edeb277600a6 153 Pfam PF04191 Phospholipid methyltransferase 40 140 1.9E-12 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 SmaCSM2_RS08660 68b186c4913bcd9746e8edeb277600a6 153 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 108 153 4.0E-7 T 28-03-2018 SmaCSM2_RS20065 bc561c5f2a5e79e64bee8e9e773a5136 132 Pfam PF15588 Immunity protein 10 6 101 4.6E-19 T 28-03-2018 IPR028962 Immunity protein 10 SmaCSM2_RS02130 0e4b92962449e2ab1a8e06e89b714c6f 159 Gene3D G3DSA:3.10.450.50 11 153 1.3E-14 T 28-03-2018 SmaCSM2_RS02130 0e4b92962449e2ab1a8e06e89b714c6f 159 SUPERFAMILY SSF54427 16 147 1.09E-15 T 28-03-2018 IPR032710 NTF2-like domain SmaCSM2_RS02130 0e4b92962449e2ab1a8e06e89b714c6f 159 Pfam PF14534 Domain of unknown function (DUF4440) 27 146 8.1E-14 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SmaCSM2_RS01390 dc83b5d2aff293998acf3038ff2074d4 73 Pfam PF05532 CsbD-like 4 56 2.3E-20 T 28-03-2018 IPR008462 CsbD-like domain SmaCSM2_RS01390 dc83b5d2aff293998acf3038ff2074d4 73 SUPERFAMILY SSF69047 1 66 9.55E-25 T 28-03-2018 IPR008462 CsbD-like domain SmaCSM2_RS01390 dc83b5d2aff293998acf3038ff2074d4 73 PIRSF PIRSF039008 1 66 4.8E-30 T 28-03-2018 IPR026042 Stress response protein YjbJ SmaCSM2_RS01390 dc83b5d2aff293998acf3038ff2074d4 73 Gene3D G3DSA:1.10.1470.10 1 69 7.1E-22 T 28-03-2018 IPR008462 CsbD-like domain SmaCSM2_RS19065 31144bc227dd95f26eb1f1ca8d6687a6 375 Gene3D G3DSA:3.40.50.450 112 266 2.3E-36 T 28-03-2018 SmaCSM2_RS19065 31144bc227dd95f26eb1f1ca8d6687a6 375 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 70 285 6.7E-69 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SmaCSM2_RS19065 31144bc227dd95f26eb1f1ca8d6687a6 375 Pfam PF02481 DNA recombination-mediator protein A 71 277 3.2E-71 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SmaCSM2_RS19065 31144bc227dd95f26eb1f1ca8d6687a6 375 SUPERFAMILY SSF102405 81 286 3.82E-42 T 28-03-2018 SmaCSM2_RS19910 c3ddb561ef3472ade97705ca4af120b0 96 Pfam PF13670 Peptidase propeptide and YPEB domain 7 93 4.6E-7 T 28-03-2018 IPR025711 PepSY domain SmaCSM2_RS19910 c3ddb561ef3472ade97705ca4af120b0 96 Gene3D G3DSA:3.10.450.40 22 93 1.1E-8 T 28-03-2018 SmaCSM2_RS20010 289f90aa69cd486a9965d4a5f116ea6a 173 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 113 1.8E-6 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS20010 289f90aa69cd486a9965d4a5f116ea6a 173 Gene3D G3DSA:1.20.1290.10 16 173 3.9E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS20010 289f90aa69cd486a9965d4a5f116ea6a 173 SUPERFAMILY SSF69118 6 172 1.85E-31 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS06390 21d9e061f9047694912fa7c75a4bdae1 137 Pfam PF03203 MerC mercury resistance protein 12 124 1.5E-26 T 28-03-2018 IPR004891 MerC mercury resistance protein SmaCSM2_RS03380 2901d5c05b5a6f5201eea904faac54aa 168 SUPERFAMILY SSF54637 6 152 1.1E-45 T 28-03-2018 IPR029069 HotDog domain SmaCSM2_RS03380 2901d5c05b5a6f5201eea904faac54aa 168 Pfam PF03061 Thioesterase superfamily 25 97 4.9E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SmaCSM2_RS03380 2901d5c05b5a6f5201eea904faac54aa 168 Gene3D G3DSA:3.10.129.10 2 158 7.6E-49 T 28-03-2018 SmaCSM2_RS15455 ce31690f8de43b444acf824b20750a68 527 Pfam PF01593 Flavin containing amine oxidoreductase 14 328 1.1E-15 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SmaCSM2_RS15455 ce31690f8de43b444acf824b20750a68 527 SUPERFAMILY SSF51905 1 347 1.3E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15455 ce31690f8de43b444acf824b20750a68 527 SUPERFAMILY SSF51905 382 408 1.3E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS15455 ce31690f8de43b444acf824b20750a68 527 Gene3D G3DSA:3.50.50.60 1 525 2.7E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS17730 4a8e7b7d7c8bf8d7a0db277e4b4d4351 525 ProSitePatterns PS01303 BCCT family of transporters signature. 303 312 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17730 4a8e7b7d7c8bf8d7a0db277e4b4d4351 525 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 40 485 5.0E-152 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17730 4a8e7b7d7c8bf8d7a0db277e4b4d4351 525 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 485 5.2E-184 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS04270 1bf94b210595e52a79af2fd454d5f361 259 Pfam PF02674 Colicin V production protein 2 140 1.7E-26 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 263 332 1.7E-19 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 Gene3D G3DSA:3.30.2420.10 281 333 4.5E-17 T 28-03-2018 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 261 328 4.8E-18 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 SUPERFAMILY SSF74653 255 320 2.75E-21 T 28-03-2018 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 Gene3D G3DSA:3.40.190.10 14 280 0.0013 T 28-03-2018 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 PRINTS PR01374 Gram-negative bacterial tonB protein signature 278 296 1.2E-10 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 PRINTS PR01374 Gram-negative bacterial tonB protein signature 257 278 1.2E-10 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 SmaCSM2_RS20860 4241a4c83713330ffe3049a9753d7d1c 337 PRINTS PR01374 Gram-negative bacterial tonB protein signature 297 314 1.2E-10 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 SmaCSM2_RS09200 7dc395e7c74056fcfe8197d19fe4565c 151 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 134 1.6E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SmaCSM2_RS09200 7dc395e7c74056fcfe8197d19fe4565c 151 Gene3D G3DSA:3.30.530.20 2 149 1.3E-26 T 28-03-2018 IPR023393 START-like domain SmaCSM2_RS09200 7dc395e7c74056fcfe8197d19fe4565c 151 SUPERFAMILY SSF55961 3 142 6.64E-26 T 28-03-2018 SmaCSM2_RS06960 681e12d54f773f9642a8130a6b2b11fb 545 Pfam PF03929 PepSY-associated TM region 10 371 4.3E-63 T 28-03-2018 IPR005625 PepSY-associated TM protein SmaCSM2_RS13155 15d81c338e559f3403ab23e0f0d8bfa1 180 SUPERFAMILY SSF55729 16 173 1.54E-41 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS13155 15d81c338e559f3403ab23e0f0d8bfa1 180 Pfam PF13302 Acetyltransferase (GNAT) domain 16 149 7.2E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS13155 15d81c338e559f3403ab23e0f0d8bfa1 180 Gene3D G3DSA:3.40.630.30 2 178 5.3E-35 T 28-03-2018 SmaCSM2_RS17210 49b4ca7aa75ec1e634c0217900606599 185 Gene3D G3DSA:2.30.110.10 5 179 2.2E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS17210 49b4ca7aa75ec1e634c0217900606599 185 SUPERFAMILY SSF50475 6 171 3.97E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SmaCSM2_RS17210 49b4ca7aa75ec1e634c0217900606599 185 SMART SM00903 16 167 5.4E-16 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS17210 49b4ca7aa75ec1e634c0217900606599 185 Pfam PF01613 Flavin reductase like domain 20 163 1.8E-19 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SmaCSM2_RS15465 78919cc92cb856628f97138d5051d2a1 102 Gene3D G3DSA:1.10.10.10 1 101 3.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS15465 78919cc92cb856628f97138d5051d2a1 102 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 2 76 2.9E-17 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS15465 78919cc92cb856628f97138d5051d2a1 102 SUPERFAMILY SSF46767 2 77 7.85E-17 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SmaCSM2_RS10375 dcceb74b02939b1ca941ab2c5d957f93 153 SUPERFAMILY SSF55811 8 142 9.88E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS10375 dcceb74b02939b1ca941ab2c5d957f93 153 Gene3D G3DSA:3.90.79.10 5 153 2.3E-29 T 28-03-2018 SmaCSM2_RS10375 dcceb74b02939b1ca941ab2c5d957f93 153 Pfam PF00293 NUDIX domain 12 125 6.9E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS10375 dcceb74b02939b1ca941ab2c5d957f93 153 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SmaCSM2_RS07920 b1c46694519a7c8d495af0fc2000112f 144 SUPERFAMILY SSF54975 3 109 7.19E-31 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SmaCSM2_RS07920 b1c46694519a7c8d495af0fc2000112f 144 SMART SM01034 3 95 9.4E-31 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS07920 b1c46694519a7c8d495af0fc2000112f 144 Pfam PF04940 Sensors of blue-light using FAD 3 94 2.4E-28 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS01850 a1c7e447785cba6b69bff6ca2e7f4cc9 314 Pfam PF03631 Virulence factor BrkB 43 290 8.7E-50 T 28-03-2018 IPR017039 Virulence factor BrkB SmaCSM2_RS01850 a1c7e447785cba6b69bff6ca2e7f4cc9 314 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 30 289 2.1E-27 T 28-03-2018 IPR017039 Virulence factor BrkB SmaCSM2_RS01850 a1c7e447785cba6b69bff6ca2e7f4cc9 314 PIRSF PIRSF035875 21 308 2.9E-61 T 28-03-2018 IPR017039 Virulence factor BrkB SmaCSM2_RS21325 b5b2db533dd1ee183961e29e0e75ff9a 240 Pfam PF00535 Glycosyl transferase family 2 7 168 7.0E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS21325 b5b2db533dd1ee183961e29e0e75ff9a 240 Gene3D G3DSA:3.90.550.10 2 238 8.7E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS21325 b5b2db533dd1ee183961e29e0e75ff9a 240 SUPERFAMILY SSF53448 2 227 2.08E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS10135 5895e896de16ef1af018b3deefd62b45 139 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 39 106 1.8E-23 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 SmaCSM2_RS10135 5895e896de16ef1af018b3deefd62b45 139 Pfam PF04347 Flagellar biosynthesis protein, FliO 51 135 2.0E-23 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 SmaCSM2_RS05400 f9b43990aae8d168ea6c17748a1cb1a3 332 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 91 105 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SmaCSM2_RS05400 f9b43990aae8d168ea6c17748a1cb1a3 332 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SmaCSM2_RS05400 f9b43990aae8d168ea6c17748a1cb1a3 332 Pfam PF00348 Polyprenyl synthetase 41 275 7.3E-76 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SmaCSM2_RS05400 f9b43990aae8d168ea6c17748a1cb1a3 332 Gene3D G3DSA:1.10.600.10 4 332 1.4E-99 T 28-03-2018 IPR008949 Isoprenoid synthase domain SmaCSM2_RS05400 f9b43990aae8d168ea6c17748a1cb1a3 332 SUPERFAMILY SSF48576 15 331 6.56E-97 T 28-03-2018 IPR008949 Isoprenoid synthase domain SmaCSM2_RS06510 7d28656cc5837b8263fc84c891870869 118 Gene3D G3DSA:3.90.1590.10 1 117 5.4E-22 T 28-03-2018 SmaCSM2_RS06510 7d28656cc5837b8263fc84c891870869 118 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 97 1.2E-7 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 SmaCSM2_RS06510 7d28656cc5837b8263fc84c891870869 118 SUPERFAMILY SSF51316 1 111 4.08E-25 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS17240 0b53364b56ca0254d3daf90b33354c78 571 Pfam PF13584 Oxygen tolerance 24 462 3.0E-71 T 28-03-2018 IPR025738 Aerotolerance-related protein BatD SmaCSM2_RS07050 10c8123e4ec0cbbee3fe628f0e8855a1 310 Gene3D G3DSA:1.10.3720.10 15 310 1.0E-47 T 28-03-2018 SmaCSM2_RS07050 10c8123e4ec0cbbee3fe628f0e8855a1 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 304 1.9E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS07050 10c8123e4ec0cbbee3fe628f0e8855a1 310 SUPERFAMILY SSF161098 15 300 8.04E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 SUPERFAMILY SSF46785 3 113 1.25E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 Gene3D G3DSA:3.40.190.10 179 266 3.4E-24 T 28-03-2018 SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 Gene3D G3DSA:1.10.10.10 2 89 2.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 Pfam PF03466 LysR substrate binding domain 90 295 2.0E-42 T 28-03-2018 IPR005119 LysR, substrate-binding SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 SUPERFAMILY SSF53850 91 299 8.14E-43 T 28-03-2018 SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 7.5E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SmaCSM2_RS21685 af951d2d5bf6e7da3b811737632e87c5 323 Gene3D G3DSA:3.40.190.10 90 178 3.1E-15 T 28-03-2018 SmaCSM2_RS02215 64a2c8146f6fabcf73c56521e38dc7a1 394 SUPERFAMILY SSF103473 8 389 7.32E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS02215 64a2c8146f6fabcf73c56521e38dc7a1 394 Gene3D G3DSA:1.20.1250.20 16 207 5.3E-22 T 28-03-2018 SmaCSM2_RS02215 64a2c8146f6fabcf73c56521e38dc7a1 394 Gene3D G3DSA:1.20.1250.20 208 392 1.5E-9 T 28-03-2018 SmaCSM2_RS02215 64a2c8146f6fabcf73c56521e38dc7a1 394 Pfam PF07690 Major Facilitator Superfamily 28 240 1.3E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS17875 5f73fde18ee70ad797083c44d1d49ffe 389 Pfam PF07396 Phosphate-selective porin O and P 41 389 1.3E-84 T 28-03-2018 IPR010870 Phosphate-selective porin O/P SmaCSM2_RS17875 5f73fde18ee70ad797083c44d1d49ffe 389 SUPERFAMILY SSF56935 248 376 1.41E-11 T 28-03-2018 SmaCSM2_RS17875 5f73fde18ee70ad797083c44d1d49ffe 389 SUPERFAMILY SSF56935 77 220 1.41E-11 T 28-03-2018 SmaCSM2_RS17875 5f73fde18ee70ad797083c44d1d49ffe 389 Gene3D G3DSA:2.40.160.10 35 389 1.5E-35 T 28-03-2018 SmaCSM2_RS05815 0d8d85f5e19599fe7aa4670a81fc9a60 59 Pfam PF13783 Domain of unknown function (DUF4177) 5 55 1.7E-8 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 SmaCSM2_RS07780 f52931b5de5e246fae77f82ab3ae170d 186 Pfam PF11198 Protein of unknown function (DUF2857) 8 182 1.6E-62 T 28-03-2018 IPR021364 Protein of unknown function DUF2857 SmaCSM2_RS01835 b7185d7dfc1336a9d2f20957eebf314d 323 PIRSF PIRSF026166 1 323 5.4E-128 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter SmaCSM2_RS01835 b7185d7dfc1336a9d2f20957eebf314d 323 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 11 320 5.3E-96 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter SmaCSM2_RS09365 df276a0774873deb5c28b126e13e3a59 256 Pfam PF08241 Methyltransferase domain 46 138 7.4E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SmaCSM2_RS09365 df276a0774873deb5c28b126e13e3a59 256 SUPERFAMILY SSF53335 7 155 7.43E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS09365 df276a0774873deb5c28b126e13e3a59 256 Gene3D G3DSA:3.40.50.150 5 255 3.8E-22 T 28-03-2018 SmaCSM2_RS03890 9a15731a43c733afa148a9b5b8958d61 338 SUPERFAMILY SSF56235 25 327 1.0E-93 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SmaCSM2_RS03890 9a15731a43c733afa148a9b5b8958d61 338 Gene3D G3DSA:3.60.20.30 197 334 2.8E-50 T 28-03-2018 SmaCSM2_RS03890 9a15731a43c733afa148a9b5b8958d61 338 Pfam PF01112 Asparaginase 25 327 1.0E-115 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 SmaCSM2_RS20505 035243c16cd685b0ca6d9141b3ab7ae6 297 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 12 295 28.7 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 SmaCSM2_RS20505 035243c16cd685b0ca6d9141b3ab7ae6 297 Pfam PF01040 UbiA prenyltransferase family 35 279 1.8E-60 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SmaCSM2_RS20505 035243c16cd685b0ca6d9141b3ab7ae6 297 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 17 294 6.7E-107 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 SmaCSM2_RS20505 035243c16cd685b0ca6d9141b3ab7ae6 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 74 96 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site SmaCSM2_RS10480 71b1b42516e1135fe13a83d8883d9a53 458 SUPERFAMILY SSF50974 146 426 9.68E-29 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SmaCSM2_RS10480 71b1b42516e1135fe13a83d8883d9a53 458 Gene3D G3DSA:2.130.10.10 133 445 1.4E-32 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SmaCSM2_RS10480 71b1b42516e1135fe13a83d8883d9a53 458 Gene3D G3DSA:2.60.40.230 40 120 8.9E-4 T 28-03-2018 SmaCSM2_RS18815 9a8661883e8370d7ae2a8a45921c1ee6 641 Pfam PF13632 Glycosyl transferase family group 2 238 432 1.2E-12 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS18815 9a8661883e8370d7ae2a8a45921c1ee6 641 Gene3D G3DSA:3.90.550.10 124 401 2.5E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS18815 9a8661883e8370d7ae2a8a45921c1ee6 641 SUPERFAMILY SSF53448 138 432 1.69E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS18815 9a8661883e8370d7ae2a8a45921c1ee6 641 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 1 641 45.908 T 28-03-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 SmaCSM2_RS04790 3c0c6fdb722da58823ee874c7df135bf 260 SUPERFAMILY SSF56112 12 144 6.97E-6 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS04790 3c0c6fdb722da58823ee874c7df135bf 260 Gene3D G3DSA:1.10.510.10 46 231 1.2E-4 T 28-03-2018 SmaCSM2_RS07935 5c34185debcb53a88e019e02cf7628c2 153 Pfam PF13673 Acetyltransferase (GNAT) domain 57 136 2.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS07935 5c34185debcb53a88e019e02cf7628c2 153 Gene3D G3DSA:3.40.630.30 1 153 9.9E-25 T 28-03-2018 SmaCSM2_RS07935 5c34185debcb53a88e019e02cf7628c2 153 SUPERFAMILY SSF55729 1 149 4.01E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 Gene3D G3DSA:2.170.130.10 24 178 4.5E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 SUPERFAMILY SSF56935 686 738 3.97E-102 T 28-03-2018 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 SUPERFAMILY SSF56935 395 633 3.97E-102 T 28-03-2018 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 SUPERFAMILY SSF56935 768 953 3.97E-102 T 28-03-2018 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 SUPERFAMILY SSF56935 25 234 3.97E-102 T 28-03-2018 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 SUPERFAMILY SSF56935 315 366 3.97E-102 T 28-03-2018 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 174 8.1E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 Pfam PF00593 TonB dependent receptor 369 951 3.3E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS18155 963ddfe3f600779a1f34e0e769d6561a 953 Gene3D G3DSA:2.40.170.20 179 953 2.0E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 SmaCSM2_RS16950 c59e4592970f34dbca0ecd35fff9497d 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 191 3.1E-49 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SmaCSM2_RS16950 c59e4592970f34dbca0ecd35fff9497d 203 Pfam PF01121 Dephospho-CoA kinase 4 182 2.3E-57 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SmaCSM2_RS16950 c59e4592970f34dbca0ecd35fff9497d 203 Gene3D G3DSA:3.40.50.300 2 202 3.2E-37 T 28-03-2018 SmaCSM2_RS16950 c59e4592970f34dbca0ecd35fff9497d 203 SUPERFAMILY SSF52540 4 200 9.23E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16950 c59e4592970f34dbca0ecd35fff9497d 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 3 200 25.985 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SmaCSM2_RS17910 025409a09009c701f6c496720e9b3204 442 Pfam PF03600 Citrate transporter 13 386 1.1E-57 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SmaCSM2_RS17910 025409a09009c701f6c496720e9b3204 442 TIGRFAM TIGR00784 citMHS: citrate transporter 1 437 2.7E-189 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SmaCSM2_RS01110 3c0fb9afd09a25fa0e798ef90fca989a 211 PIRSF PIRSF006324 2 210 1.3E-44 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS01110 3c0fb9afd09a25fa0e798ef90fca989a 211 Pfam PF01810 LysE type translocator 16 208 5.2E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS00600 7093fd72add40fd5e6ed9712919035b1 203 Gene3D G3DSA:3.90.280.10 1 199 1.2E-48 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SmaCSM2_RS00600 7093fd72add40fd5e6ed9712919035b1 203 SUPERFAMILY SSF49777 1 198 4.06E-42 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SmaCSM2_RS00600 7093fd72add40fd5e6ed9712919035b1 203 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 28 195 3.2E-26 T 28-03-2018 IPR005247 YbhB/YbcL SmaCSM2_RS00600 7093fd72add40fd5e6ed9712919035b1 203 Pfam PF01161 Phosphatidylethanolamine-binding protein 26 196 3.3E-39 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SmaCSM2_RS03175 d2cf44d499f38f6d6e8b6d422b6a20d8 673 Pfam PF01757 Acyltransferase family 28 347 1.2E-29 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SmaCSM2_RS03175 d2cf44d499f38f6d6e8b6d422b6a20d8 673 Gene3D G3DSA:3.40.50.1110 410 668 1.2E-10 T 28-03-2018 SmaCSM2_RS09395 cc6b4826940da8c290cded06efdf4608 154 Gene3D G3DSA:3.40.630.30 4 145 1.2E-27 T 28-03-2018 SmaCSM2_RS09395 cc6b4826940da8c290cded06efdf4608 154 Pfam PF00583 Acetyltransferase (GNAT) family 45 135 9.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS09395 cc6b4826940da8c290cded06efdf4608 154 SUPERFAMILY SSF55729 1 139 3.88E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS19980 708b4ea1afa9fa1e757fb5215c6b9ce7 247 SUPERFAMILY SSF54373 81 179 8.5E-22 T 28-03-2018 SmaCSM2_RS19980 708b4ea1afa9fa1e757fb5215c6b9ce7 247 SUPERFAMILY SSF51905 199 236 4.33E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19980 708b4ea1afa9fa1e757fb5215c6b9ce7 247 SUPERFAMILY SSF51905 12 100 4.33E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS19980 708b4ea1afa9fa1e757fb5215c6b9ce7 247 Gene3D G3DSA:3.90.660.10 10 181 1.0E-25 T 28-03-2018 SmaCSM2_RS19980 708b4ea1afa9fa1e757fb5215c6b9ce7 247 Pfam PF01593 Flavin containing amine oxidoreductase 8 236 6.1E-23 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SmaCSM2_RS19590 61fed40cf2f75dfdf79b363d0164e8e1 301 Gene3D G3DSA:3.90.79.10 160 301 2.2E-33 T 28-03-2018 SmaCSM2_RS19590 61fed40cf2f75dfdf79b363d0164e8e1 301 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 128 158 8.1E-7 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 SmaCSM2_RS19590 61fed40cf2f75dfdf79b363d0164e8e1 301 SUPERFAMILY SSF55811 112 270 1.06E-39 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SmaCSM2_RS19590 61fed40cf2f75dfdf79b363d0164e8e1 301 Pfam PF00293 NUDIX domain 164 274 2.8E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SmaCSM2_RS03520 e28d41b8b2c664e74d4709287dc5539c 164 Pfam PF04536 TPM domain 18 138 1.1E-10 T 28-03-2018 IPR007621 TPM domain SmaCSM2_RS13970 f26982174f28094892896af42710d172 183 Pfam PF11159 Protein of unknown function (DUF2939) 12 104 1.8E-28 T 28-03-2018 IPR021330 Protein of unknown function DUF2939 SmaCSM2_RS02240 2bdba78a43e99a422fe49016d97e7b5e 506 Gene3D G3DSA:1.25.40.10 33 258 1.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS02240 2bdba78a43e99a422fe49016d97e7b5e 506 SUPERFAMILY SSF48452 310 370 1.85E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS02240 2bdba78a43e99a422fe49016d97e7b5e 506 SUPERFAMILY SSF48452 85 155 1.85E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS02240 2bdba78a43e99a422fe49016d97e7b5e 506 Gene3D G3DSA:1.25.40.10 262 490 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS18980 750662abdc6412d629e2cde9109727ec 225 Gene3D G3DSA:2.60.40.1180 125 222 1.8E-6 T 28-03-2018 SmaCSM2_RS17925 f1264c59ce626d7822b9febed746e409 417 TIGRFAM TIGR02421 QEGLA: conserved hypothetical protein 21 403 2.9E-110 T 28-03-2018 IPR012656 Conserved hypothetical protein CHP02421, QEGLA SmaCSM2_RS17925 f1264c59ce626d7822b9febed746e409 417 SMART SM01154 41 410 2.3E-150 T 28-03-2018 IPR012548 Protein of unknown function DUF1704 SmaCSM2_RS17925 f1264c59ce626d7822b9febed746e409 417 Pfam PF08014 Domain of unknown function (DUF1704) 49 407 3.6E-121 T 28-03-2018 IPR012548 Protein of unknown function DUF1704 SmaCSM2_RS00285 70e1b012ca9f100786714b00cb0ff4f0 400 Pfam PF16024 Domain of unknown function (DUF4785) 64 365 1.4E-13 T 28-03-2018 IPR031979 Protein of unknown function DUF4785 SmaCSM2_RS10565 d75bd9e0f2456bd3d575d1a16b5cf93e 425 Pfam PF01593 Flavin containing amine oxidoreductase 10 281 2.9E-15 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SmaCSM2_RS10565 d75bd9e0f2456bd3d575d1a16b5cf93e 425 Gene3D G3DSA:3.90.660.20 32 370 2.3E-32 T 28-03-2018 SmaCSM2_RS10565 d75bd9e0f2456bd3d575d1a16b5cf93e 425 SUPERFAMILY SSF51905 1 297 1.81E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS10565 d75bd9e0f2456bd3d575d1a16b5cf93e 425 SUPERFAMILY SSF51905 377 408 1.81E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SmaCSM2_RS03250 08faf8f308ed717f7fed5e2cc926f23c 361 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 359 24.88 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03250 08faf8f308ed717f7fed5e2cc926f23c 361 Pfam PF00953 Glycosyl transferase family 4 99 285 5.6E-33 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SmaCSM2_RS03250 08faf8f308ed717f7fed5e2cc926f23c 361 ProSitePatterns PS01348 MraY family signature 2. 190 201 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03250 08faf8f308ed717f7fed5e2cc926f23c 361 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 361 1.8E-131 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS03250 08faf8f308ed717f7fed5e2cc926f23c 361 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SmaCSM2_RS04780 255c777f191a1c449e1af05fb18f4272 64 Pfam PF01783 Ribosomal L32p protein family 2 55 3.7E-21 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04780 255c777f191a1c449e1af05fb18f4272 64 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 18.02 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04780 255c777f191a1c449e1af05fb18f4272 64 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.4E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS04780 255c777f191a1c449e1af05fb18f4272 64 SUPERFAMILY SSF57829 2 55 1.1E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SmaCSM2_RS02555 3c67279da177557fbd15af649a843c86 190 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 46 170 1.2E-51 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02555 3c67279da177557fbd15af649a843c86 190 Pfam PF01641 SelR domain 50 168 6.4E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SmaCSM2_RS02555 3c67279da177557fbd15af649a843c86 190 SUPERFAMILY SSF51316 45 170 1.67E-56 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS02555 3c67279da177557fbd15af649a843c86 190 Gene3D G3DSA:2.170.150.20 36 180 4.8E-59 T 28-03-2018 SmaCSM2_RS21290 fe7155b09e1a76332ece62f19ea71e7a 132 Pfam PF01042 Endoribonuclease L-PSP 13 127 5.3E-26 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SmaCSM2_RS21290 fe7155b09e1a76332ece62f19ea71e7a 132 SUPERFAMILY SSF55298 8 129 3.93E-35 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS21290 fe7155b09e1a76332ece62f19ea71e7a 132 Gene3D G3DSA:3.30.1330.40 1 131 2.1E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS13400 4ff10207a3ab3785ecf1cea1c434cfcb 815 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 171 376 1.4E-49 T 28-03-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 SmaCSM2_RS13400 4ff10207a3ab3785ecf1cea1c434cfcb 815 SUPERFAMILY SSF52540 385 711 6.07E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS13400 4ff10207a3ab3785ecf1cea1c434cfcb 815 Gene3D G3DSA:3.40.50.300 399 738 1.2E-16 T 28-03-2018 SmaCSM2_RS13400 4ff10207a3ab3785ecf1cea1c434cfcb 815 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 6 799 5.5E-225 T 28-03-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 SmaCSM2_RS03075 7bc04a51a6e4d5495fa181c986fc8e04 321 Pfam PF14488 Domain of unknown function (DUF4434) 30 196 4.5E-38 T 28-03-2018 IPR027849 Protein of unknown function DUF4434 SmaCSM2_RS03075 7bc04a51a6e4d5495fa181c986fc8e04 321 Gene3D G3DSA:3.20.20.150 4 321 6.3E-5 T 28-03-2018 SmaCSM2_RS14320 6862693a1d632854135c5389bd056917 282 SUPERFAMILY SSF56219 56 199 2.16E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS14320 6862693a1d632854135c5389bd056917 282 Gene3D G3DSA:3.60.10.10 18 215 1.8E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS14320 6862693a1d632854135c5389bd056917 282 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 52 198 8.4E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SmaCSM2_RS00645 94eaca73dda8afae4a1a7418422bac4c 248 SUPERFAMILY SSF55846 30 183 1.44E-46 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS00645 94eaca73dda8afae4a1a7418422bac4c 248 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 43 167 4.3E-30 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS00645 94eaca73dda8afae4a1a7418422bac4c 248 SMART SM00644 34 167 1.1E-30 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS00645 94eaca73dda8afae4a1a7418422bac4c 248 Gene3D G3DSA:3.40.80.10 20 180 1.6E-41 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 Gene3D G3DSA:3.40.50.720 4 259 4.8E-55 T 28-03-2018 SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 SUPERFAMILY SSF51735 12 256 9.8E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 7.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 7.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 7.4E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SmaCSM2_RS09815 017a2f214e49cb51a2696fe9acd0d829 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 4.8E-53 T 28-03-2018 SmaCSM2_RS19015 b244823dc563fdc54c413c3466bac4fb 166 Pfam PF03703 Bacterial PH domain 78 155 4.7E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SmaCSM2_RS15055 f5f598adbe47c36330d5b8aac02341ba 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 2.5E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS15055 f5f598adbe47c36330d5b8aac02341ba 134 Gene3D G3DSA:3.10.180.10 8 134 8.2E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS15055 f5f598adbe47c36330d5b8aac02341ba 134 SUPERFAMILY SSF54593 6 123 2.95E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 130 35.866 T 28-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 26 129 6.8E-39 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 Gene3D G3DSA:2.60.300.12 25 130 3.5E-39 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 111 128 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 Pfam PF01521 Iron-sulphur cluster biosynthesis 25 125 7.4E-21 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS19595 e683a079d8aa7f4f2fa6b74299a1cea4 130 SUPERFAMILY SSF89360 25 119 1.96E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 SUPERFAMILY SSF52540 187 574 1.14E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 Pfam PF00437 Type II/IV secretion system protein 199 466 5.9E-88 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 49 149 1.6E-17 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 Gene3D G3DSA:3.30.450.90 174 299 2.5E-45 T 28-03-2018 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 14 576 1.5E-260 T 28-03-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 Gene3D G3DSA:3.40.50.300 300 576 6.0E-61 T 28-03-2018 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 SUPERFAMILY SSF160246 11 146 3.66E-29 T 28-03-2018 SmaCSM2_RS16925 25b1d182563b25ed108a4978301ccdde 576 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 394 408 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SmaCSM2_RS17445 c39e397ab4987461d4952ee973758cff 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 50.22 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 SmaCSM2_RS17445 c39e397ab4987461d4952ee973758cff 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 1.6E-58 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SmaCSM2_RS17445 c39e397ab4987461d4952ee973758cff 198 Gene3D G3DSA:3.90.950.10 1 197 5.5E-78 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS17445 c39e397ab4987461d4952ee973758cff 198 SUPERFAMILY SSF52972 1 195 2.88E-71 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SmaCSM2_RS17445 c39e397ab4987461d4952ee973758cff 198 Pfam PF01725 Ham1 family 4 192 4.1E-55 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SmaCSM2_RS11575 5a6e748c104672cd26cc339d059cfe11 89 Pfam PF11747 Killing trait 11 77 1.5E-30 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS04930 ac8fdd5aa784d6737ebfd149d3593c4a 134 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 39 114 2.4E-8 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 SmaCSM2_RS04930 ac8fdd5aa784d6737ebfd149d3593c4a 134 SUPERFAMILY SSF51316 12 133 8.89E-30 T 28-03-2018 IPR011057 Mss4-like SmaCSM2_RS04930 ac8fdd5aa784d6737ebfd149d3593c4a 134 Gene3D G3DSA:3.90.1590.10 4 121 5.2E-19 T 28-03-2018 SmaCSM2_RS16690 94f6d3df94d82efc7e0d2433a859b44b 259 Pfam PF01618 MotA/TolQ/ExbB proton channel family 112 241 5.9E-38 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 SmaCSM2_RS16690 94f6d3df94d82efc7e0d2433a859b44b 259 TIGRFAM TIGR02796 tolQ: protein TolQ 38 253 3.8E-85 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 SmaCSM2_RS08465 e7b011e90d8bad658d9925009128ad95 413 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 413 1.2E-135 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 SmaCSM2_RS08465 e7b011e90d8bad658d9925009128ad95 413 Pfam PF02687 FtsX-like permease family 300 406 7.2E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS08465 e7b011e90d8bad658d9925009128ad95 413 Pfam PF12704 MacB-like periplasmic core domain 28 197 2.1E-15 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS07985 116836b9b39eac25feb59f5d01437408 373 Pfam PF01384 Phosphate transporter family 19 358 2.4E-80 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SmaCSM2_RS20990 2cd2936690c85b187435ae700623d3b9 406 Pfam PF01139 tRNA-splicing ligase RtcB 34 406 3.7E-129 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SmaCSM2_RS20990 2cd2936690c85b187435ae700623d3b9 406 SUPERFAMILY SSF103365 13 406 1.03E-131 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 Gene3D G3DSA:1.10.10.60 7 38 1.9E-8 T 28-03-2018 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 SUPERFAMILY SSF46689 11 81 5.49E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 Gene3D G3DSA:1.10.357.10 78 205 3.7E-18 T 28-03-2018 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 SUPERFAMILY SSF48498 81 165 1.0E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS13990 522a463a6948a2a9fadcea251392d333 218 Gene3D G3DSA:1.10.260.40 39 77 1.8E-8 T 28-03-2018 SmaCSM2_RS08655 a441df160a865401a3cf6d409cfbc58c 673 SUPERFAMILY SSF53474 382 645 6.04E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08655 a441df160a865401a3cf6d409cfbc58c 673 Gene3D G3DSA:3.40.50.1820 371 663 1.5E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08655 a441df160a865401a3cf6d409cfbc58c 673 Pfam PF07819 PGAP1-like protein 388 501 1.9E-6 T 28-03-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 SmaCSM2_RS01145 009008743a0d10646f6a40626d44aa96 208 Pfam PF00857 Isochorismatase family 9 193 9.0E-22 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS01145 009008743a0d10646f6a40626d44aa96 208 SUPERFAMILY SSF52499 4 206 6.02E-44 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS01145 009008743a0d10646f6a40626d44aa96 208 Gene3D G3DSA:3.40.50.850 1 208 3.3E-51 T 28-03-2018 SmaCSM2_RS06665 c691af28a1e54957720bfd5986a0e3f5 345 Pfam PF05229 Spore Coat Protein U domain 18 165 2.2E-16 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS06665 c691af28a1e54957720bfd5986a0e3f5 345 Pfam PF05229 Spore Coat Protein U domain 204 342 2.8E-31 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS06665 c691af28a1e54957720bfd5986a0e3f5 345 SMART SM00972 99 168 0.0066 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS06665 c691af28a1e54957720bfd5986a0e3f5 345 SMART SM00972 283 342 7.5E-23 T 28-03-2018 IPR007893 Spore coat protein U SmaCSM2_RS07310 66f95d8d0204bd2ff43a305534196484 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 136 8.9E-32 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS14385 863652f4e9f4bcf00a79b776fb5d23b9 278 Gene3D G3DSA:1.10.3720.10 2 265 4.2E-46 T 28-03-2018 SmaCSM2_RS14385 863652f4e9f4bcf00a79b776fb5d23b9 278 SUPERFAMILY SSF161098 8 278 1.96E-75 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS14385 863652f4e9f4bcf00a79b776fb5d23b9 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 265 1.4E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SmaCSM2_RS11775 8a8ee9cbab4b9cef82340e7ba35fb188 144 Pfam PF00892 EamA-like transporter family 7 141 1.5E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS11775 8a8ee9cbab4b9cef82340e7ba35fb188 144 SUPERFAMILY SSF103481 43 142 6.93E-17 T 28-03-2018 SmaCSM2_RS06555 01b19b37181f3a3d381051078ccdf085 196 Pfam PF13489 Methyltransferase domain 38 162 1.4E-9 T 28-03-2018 SmaCSM2_RS06555 01b19b37181f3a3d381051078ccdf085 196 SUPERFAMILY SSF53335 11 183 6.14E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS06555 01b19b37181f3a3d381051078ccdf085 196 Gene3D G3DSA:3.40.50.150 2 196 1.8E-17 T 28-03-2018 SmaCSM2_RS17355 83a1f4ec12d48d174390d126d6b4ea71 312 Gene3D G3DSA:3.90.245.10 1 311 1.3E-93 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS17355 83a1f4ec12d48d174390d126d6b4ea71 312 SUPERFAMILY SSF53590 4 309 3.92E-88 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS17355 83a1f4ec12d48d174390d126d6b4ea71 312 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 6 302 2.1E-78 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 Pfam PF00854 POT family 407 529 3.7E-16 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 Pfam PF00854 POT family 84 332 3.8E-35 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 161 173 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 Gene3D G3DSA:1.20.1250.20 12 218 6.1E-22 T 28-03-2018 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 Gene3D G3DSA:1.20.1250.20 375 579 2.1E-9 T 28-03-2018 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 SUPERFAMILY SSF103473 14 328 6.02E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 10 390 1.6E-62 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SmaCSM2_RS05740 24bd51caad4a3057ba2083c278695bac 584 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 72 96 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SmaCSM2_RS09840 c1a2046424db6704844f3157cffcb3ca 305 PIRSF PIRSF015283 4 305 2.9E-78 T 28-03-2018 IPR016631 Regulatory, RpfE SmaCSM2_RS05440 c24aa70ca89231ae92036c3b01037d78 154 SUPERFAMILY SSF55729 1 152 1.89E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS05440 c24aa70ca89231ae92036c3b01037d78 154 Gene3D G3DSA:3.40.630.30 1 152 3.5E-20 T 28-03-2018 SmaCSM2_RS05440 c24aa70ca89231ae92036c3b01037d78 154 Pfam PF00583 Acetyltransferase (GNAT) family 44 132 1.7E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SmaCSM2_RS08850 0ca5ce547e0a3b1dbfd775554faf17e7 419 Pfam PF07055 Enoyl reductase FAD binding domain 343 406 2.2E-28 T 28-03-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS08850 0ca5ce547e0a3b1dbfd775554faf17e7 419 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 313 1.7E-106 T 28-03-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS08850 0ca5ce547e0a3b1dbfd775554faf17e7 419 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 1.0E-36 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS08850 0ca5ce547e0a3b1dbfd775554faf17e7 419 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 412 54.391 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SmaCSM2_RS08850 0ca5ce547e0a3b1dbfd775554faf17e7 419 Gene3D G3DSA:3.40.50.1820 4 351 0.003 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS19315 fa1f399af8093cca6cc3631f88ceb9ff 242 Pfam PF08883 Dopa 4,5-dioxygenase family 115 212 2.0E-23 T 28-03-2018 IPR014980 Dopa 4,5-dioxygenase SmaCSM2_RS19315 fa1f399af8093cca6cc3631f88ceb9ff 242 SUPERFAMILY SSF143410 106 212 1.7E-33 T 28-03-2018 IPR023389 DOPA-like domain SmaCSM2_RS19315 fa1f399af8093cca6cc3631f88ceb9ff 242 Gene3D G3DSA:3.30.70.1240 107 215 2.2E-27 T 28-03-2018 IPR023389 DOPA-like domain SmaCSM2_RS01255 b734dd1201e35512af3634493292e8a8 405 Gene3D G3DSA:1.10.10.10 250 404 3.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS00445 f388ae336c897e42931b28600fbec10e 373 Gene3D G3DSA:3.40.710.10 8 360 6.5E-78 T 28-03-2018 SmaCSM2_RS00445 f388ae336c897e42931b28600fbec10e 373 Pfam PF00144 Beta-lactamase 23 338 1.9E-65 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS00445 f388ae336c897e42931b28600fbec10e 373 SUPERFAMILY SSF56601 17 342 2.74E-77 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS14910 0c3b95b77baa7f4974fc744af692a60b 148 Gene3D G3DSA:3.30.700.10 45 148 2.4E-4 T 28-03-2018 SmaCSM2_RS14910 0c3b95b77baa7f4974fc744af692a60b 148 Pfam PF00114 Pilin (bacterial filament) 47 140 3.8E-6 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 SmaCSM2_RS05425 5cf44db5bdaac8549fa253d039336336 495 Gene3D G3DSA:1.20.1250.20 298 494 1.3E-20 T 28-03-2018 SmaCSM2_RS05425 5cf44db5bdaac8549fa253d039336336 495 Gene3D G3DSA:1.20.1250.20 5 214 4.3E-21 T 28-03-2018 SmaCSM2_RS05425 5cf44db5bdaac8549fa253d039336336 495 Pfam PF07690 Major Facilitator Superfamily 18 451 6.3E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SmaCSM2_RS05425 5cf44db5bdaac8549fa253d039336336 495 SUPERFAMILY SSF103473 12 219 3.92E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS05425 5cf44db5bdaac8549fa253d039336336 495 SUPERFAMILY SSF103473 282 491 3.92E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain SmaCSM2_RS13875 5ffb5340e9aded85c85991f83c3e487c 374 SUPERFAMILY SSF53383 32 368 4.7E-61 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SmaCSM2_RS13875 5ffb5340e9aded85c85991f83c3e487c 374 Gene3D G3DSA:3.90.1150.10 263 370 9.1E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SmaCSM2_RS13875 5ffb5340e9aded85c85991f83c3e487c 374 Pfam PF00155 Aminotransferase class I and II 46 361 6.0E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SmaCSM2_RS13875 5ffb5340e9aded85c85991f83c3e487c 374 Gene3D G3DSA:3.40.640.10 57 262 2.7E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SmaCSM2_RS00880 82dd50e9c56ac2e75d20652be2452ad2 141 Pfam PF03692 Putative zinc- or iron-chelating domain 4 97 5.4E-12 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein SmaCSM2_RS10060 4e8b77e13763a17066ec168405afbcd6 260 Pfam PF13614 AAA domain 1 171 3.9E-37 T 28-03-2018 IPR025669 AAA domain SmaCSM2_RS10060 4e8b77e13763a17066ec168405afbcd6 260 Gene3D G3DSA:3.40.50.300 1 259 7.4E-48 T 28-03-2018 SmaCSM2_RS10060 4e8b77e13763a17066ec168405afbcd6 260 SUPERFAMILY SSF52540 1 251 4.56E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS20380 c46639464712f31f3e2a6529bd6fd3a4 220 Pfam PF06055 Exopolysaccharide synthesis, ExoD 15 196 4.7E-47 T 28-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD SmaCSM2_RS20380 c46639464712f31f3e2a6529bd6fd3a4 220 PIRSF PIRSF033239 3 211 9.7E-47 T 28-03-2018 IPR010331 Exopolysaccharide synthesis, ExoD SmaCSM2_RS13060 e9c7d2f04a13fd832fb7df1acf7c18ad 144 SUPERFAMILY SSF55298 25 142 1.23E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS13060 e9c7d2f04a13fd832fb7df1acf7c18ad 144 Gene3D G3DSA:3.30.1330.40 19 143 1.3E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SmaCSM2_RS13060 e9c7d2f04a13fd832fb7df1acf7c18ad 144 Pfam PF01042 Endoribonuclease L-PSP 26 142 7.5E-16 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SmaCSM2_RS19820 07605a413181e5a59fa0b625982dda7e 291 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 282 38.877 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SmaCSM2_RS19820 07605a413181e5a59fa0b625982dda7e 291 Pfam PF03301 Tryptophan 2,3-dioxygenase 207 282 4.1E-21 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SmaCSM2_RS19820 07605a413181e5a59fa0b625982dda7e 291 Pfam PF03301 Tryptophan 2,3-dioxygenase 12 147 3.5E-41 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SmaCSM2_RS19820 07605a413181e5a59fa0b625982dda7e 291 SUPERFAMILY SSF140959 23 282 3.66E-96 T 28-03-2018 SmaCSM2_RS20620 d7da34312045785c8161baf95a0bd503 183 Pfam PF03729 Short repeat of unknown function (DUF308) 22 89 1.9E-7 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane SmaCSM2_RS20620 d7da34312045785c8161baf95a0bd503 183 Pfam PF03729 Short repeat of unknown function (DUF308) 78 146 5.1E-13 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane SmaCSM2_RS20620 d7da34312045785c8161baf95a0bd503 183 Pfam PF03729 Short repeat of unknown function (DUF308) 134 181 2.3E-6 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 Pfam PF04344 Chemotaxis phosphatase, CheZ 44 110 1.6E-9 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 Pfam PF04344 Chemotaxis phosphatase, CheZ 118 200 2.5E-14 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 SUPERFAMILY SSF75708 34 200 2.88E-37 T 28-03-2018 SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 PIRSF PIRSF002884 20 120 1.6E-22 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 PIRSF PIRSF002884 114 201 2.0E-22 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 SmaCSM2_RS10080 79333ffcb55eb4adff09e6a241f5f3a5 201 Gene3D G3DSA:1.10.287.500 13 162 2.4E-7 T 28-03-2018 SmaCSM2_RS12590 25ef97154ec0a24ab18ff06de9bdcffe 108 Pfam PF00085 Thioredoxin 6 105 1.2E-11 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SmaCSM2_RS12590 25ef97154ec0a24ab18ff06de9bdcffe 108 SUPERFAMILY SSF52833 5 105 3.38E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS12590 25ef97154ec0a24ab18ff06de9bdcffe 108 Gene3D G3DSA:3.40.30.10 1 107 2.1E-18 T 28-03-2018 SmaCSM2_RS18335 e76237035a5811b26c5413b5e2d78f55 357 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 48 355 4.8E-92 T 28-03-2018 IPR018707 Protein of unknown function DUF2219 SmaCSM2_RS18335 e76237035a5811b26c5413b5e2d78f55 357 Gene3D G3DSA:2.40.128.140 36 354 2.8E-103 T 28-03-2018 IPR018707 Protein of unknown function DUF2219 SmaCSM2_RS04985 52ccc0eb4db6f6939b4f427accd4c15b 148 Gene3D G3DSA:3.20.20.70 28 101 0.0012 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS03045 8b805000b19f0d179e75bc2569e0b732 854 Pfam PF13954 PapC N-terminal domain 48 195 1.0E-41 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 SmaCSM2_RS03045 8b805000b19f0d179e75bc2569e0b732 854 SUPERFAMILY SSF141729 69 186 9.02E-29 T 28-03-2018 SmaCSM2_RS03045 8b805000b19f0d179e75bc2569e0b732 854 Pfam PF00577 Outer membrane usher protein 212 763 7.3E-172 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS03045 8b805000b19f0d179e75bc2569e0b732 854 Pfam PF13953 PapC C-terminal domain 772 837 3.0E-22 T 28-03-2018 IPR025949 PapC-like, C-terminal domain SmaCSM2_RS07240 36ec39b4e38ed3dc82335c39dd96ae32 1251 Pfam PF05567 Neisseria PilC beta-propeller domain 717 1074 9.3E-37 T 28-03-2018 IPR008707 PilC beta-propeller domain SmaCSM2_RS07240 36ec39b4e38ed3dc82335c39dd96ae32 1251 Gene3D G3DSA:3.40.50.410 42 578 4.5E-26 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS06920 c21034385b52d036199c7aa8a9c7774c 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 5.4E-66 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SmaCSM2_RS06920 c21034385b52d036199c7aa8a9c7774c 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SmaCSM2_RS06920 c21034385b52d036199c7aa8a9c7774c 260 Gene3D G3DSA:3.90.226.10 5 217 2.1E-72 T 28-03-2018 SmaCSM2_RS06920 c21034385b52d036199c7aa8a9c7774c 260 SUPERFAMILY SSF52096 6 260 1.44E-87 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SmaCSM2_RS06920 c21034385b52d036199c7aa8a9c7774c 260 Gene3D G3DSA:1.10.12.10 218 260 1.2E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal SmaCSM2_RS07700 f56ce98e607924d1ef9fa87eff638051 305 Pfam PF12101 Protein of unknown function (DUF3577) 131 257 5.5E-47 T 28-03-2018 IPR021960 Protein of unknown function DUF3577 SmaCSM2_RS07700 f56ce98e607924d1ef9fa87eff638051 305 Pfam PF12101 Protein of unknown function (DUF3577) 5 120 4.6E-37 T 28-03-2018 IPR021960 Protein of unknown function DUF3577 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 Pfam PF04389 Peptidase family M28 299 515 3.9E-47 T 28-03-2018 IPR007484 Peptidase M28 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 SUPERFAMILY SSF53187 283 527 1.49E-62 T 28-03-2018 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 SUPERFAMILY SSF53187 27 73 1.49E-62 T 28-03-2018 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 Gene3D G3DSA:3.40.630.10 232 526 5.9E-38 T 28-03-2018 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 Gene3D G3DSA:3.50.30.30 106 231 3.2E-14 T 28-03-2018 SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 Pfam PF02225 PA domain 129 234 3.8E-8 T 28-03-2018 IPR003137 PA domain SmaCSM2_RS01415 905d88dd3b6880371fdd1252041ec076 550 SUPERFAMILY SSF52025 128 212 1.83E-7 T 28-03-2018 SmaCSM2_RS21270 ca07d5749974e2c2e3f5d552a9b11daf 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 20 39 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SmaCSM2_RS21270 ca07d5749974e2c2e3f5d552a9b11daf 54 SUPERFAMILY SSF57829 3 52 2.93E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SmaCSM2_RS21270 ca07d5749974e2c2e3f5d552a9b11daf 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 4 52 13.434 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21270 ca07d5749974e2c2e3f5d552a9b11daf 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 6.0E-23 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS21270 ca07d5749974e2c2e3f5d552a9b11daf 54 Pfam PF00471 Ribosomal protein L33 7 52 1.0E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SmaCSM2_RS15845 b63091c63e7224475314b39f2abee76f 113 Gene3D G3DSA:1.20.120.20 19 113 4.2E-4 T 28-03-2018 SmaCSM2_RS12195 0ae9358e858b8a79f44dbb2b1d8d04dc 183 Gene3D G3DSA:3.40.1620.10 3 50 8.9E-4 T 28-03-2018 SmaCSM2_RS16840 35e858d42b78a473337a2e52fd63ae63 160 Pfam PF12098 Protein of unknown function (DUF3574) 51 160 4.2E-36 T 28-03-2018 IPR021957 Protein of unknown function DUF3574 SmaCSM2_RS21000 4460f2cce85d177bc68de1548f8a39e3 151 Pfam PF02082 Transcriptional regulator 1 81 1.7E-20 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SmaCSM2_RS21000 4460f2cce85d177bc68de1548f8a39e3 151 Gene3D G3DSA:1.10.10.10 1 146 5.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS21000 4460f2cce85d177bc68de1548f8a39e3 151 SUPERFAMILY SSF46785 7 135 5.68E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS16485 63a4d1d155461fde3f3804405418646c 176 Pfam PF01584 CheW-like domain 34 164 1.2E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16485 63a4d1d155461fde3f3804405418646c 176 SUPERFAMILY SSF50341 29 170 1.01E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16485 63a4d1d155461fde3f3804405418646c 176 SMART SM00260 29 150 1.7E-8 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 SmaCSM2_RS16485 63a4d1d155461fde3f3804405418646c 176 Gene3D G3DSA:2.40.50.180 52 148 4.8E-20 T 28-03-2018 SmaCSM2_RS09715 7551e5e4bb69d1870a698819dd3e2cd6 99 Pfam PF09498 Protein of unknown function (DUF2388) 30 98 1.6E-26 T 28-03-2018 IPR012661 Conserved hypothetical protein CHP02448 SmaCSM2_RS09715 7551e5e4bb69d1870a698819dd3e2cd6 99 TIGRFAM TIGR02448 TIGR02448: conserverd hypothetical protein 5 98 2.1E-27 T 28-03-2018 IPR012661 Conserved hypothetical protein CHP02448 SmaCSM2_RS02870 7cc4646a092d7b81ac307daacc7ba77e 167 Gene3D G3DSA:3.40.50.10220 104 162 2.2E-5 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SmaCSM2_RS10630 94b36f3c501bf4064954d66439b7b39c 438 Gene3D G3DSA:2.60.120.260 39 242 1.3E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS10630 94b36f3c501bf4064954d66439b7b39c 438 SUPERFAMILY SSF49785 31 155 1.56E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like SmaCSM2_RS17945 56036bb9bc6097f5921df8b5c16aff7d 239 Pfam PF08242 Methyltransferase domain 68 162 5.6E-11 T 28-03-2018 IPR013217 Methyltransferase type 12 SmaCSM2_RS17945 56036bb9bc6097f5921df8b5c16aff7d 239 Gene3D G3DSA:3.40.50.150 14 234 7.0E-28 T 28-03-2018 SmaCSM2_RS17945 56036bb9bc6097f5921df8b5c16aff7d 239 SUPERFAMILY SSF53335 34 222 2.67E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS02360 fb80eec428406e1ef31e82512b97aa91 136 Pfam PF07681 DoxX 16 97 1.4E-14 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS10920 4201d33b29f2548240350eddfacac5ed 91 Gene3D G3DSA:3.30.70.1350 1 69 1.7E-4 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SmaCSM2_RS09460 e90071233aab1376b750f38dd704ce2c 142 Pfam PF04940 Sensors of blue-light using FAD 4 94 2.4E-26 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS09460 e90071233aab1376b750f38dd704ce2c 142 SMART SM01034 3 95 1.0E-26 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS09460 e90071233aab1376b750f38dd704ce2c 142 SUPERFAMILY SSF54975 3 108 3.92E-29 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 127 450 1.5E-92 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 Pfam PF00326 Prolyl oligopeptidase family 546 740 8.6E-54 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 SUPERFAMILY SSF53474 487 740 2.06E-73 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 Gene3D G3DSA:2.140.10.30 37 474 3.1E-91 T 28-03-2018 SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 Gene3D G3DSA:3.40.50.1820 475 741 2.8E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20845 aac628007a5d4ef1bc344c3a43d6ca60 741 SUPERFAMILY SSF82171 39 468 7.59E-52 T 28-03-2018 SmaCSM2_RS03495 743867ab6639a92ef2eb2ae741bb5977 131 Pfam PF01219 Prokaryotic diacylglycerol kinase 21 120 1.6E-32 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SmaCSM2_RS03495 743867ab6639a92ef2eb2ae741bb5977 131 Gene3D G3DSA:1.10.3830.10 11 123 5.6E-38 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SmaCSM2_RS11830 e43f5efb67e362972e0c1462e54c31bb 179 Pfam PF04214 Protein of unknown function, DUF 80 148 2.5E-31 T 28-03-2018 IPR007332 Protein of unknown function DUF411 SmaCSM2_RS01095 b58729cf543572a722fe12c3e0a33326 219 Gene3D G3DSA:2.60.40.1090 28 217 6.7E-6 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 SmaCSM2_RS01095 b58729cf543572a722fe12c3e0a33326 219 Pfam PF06551 Protein of unknown function (DUF1120) 30 100 2.6E-4 T 28-03-2018 IPR010546 Protein of unknown function DUF1120 SmaCSM2_RS20785 957ef66d8799d63537095fa3ca170512 390 Pfam PF04235 Protein of unknown function (DUF418) 217 381 1.5E-38 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SmaCSM2_RS11155 dbe3e36c62bdf7116b3b0b2dc8c2068e 151 Gene3D G3DSA:2.60.40.1180 40 151 8.2E-5 T 28-03-2018 SmaCSM2_RS11155 dbe3e36c62bdf7116b3b0b2dc8c2068e 151 SUPERFAMILY SSF81901 58 131 6.93E-5 T 28-03-2018 SmaCSM2_RS14040 2404643fcd6a955852554cec613188ef 226 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 83 226 2.9E-29 T 28-03-2018 IPR018636 Protein of unknown function DUF2058 SmaCSM2_RS09770 c2217f395499058bb4ccb8caea4c2b2d 298 Gene3D G3DSA:3.20.20.70 1 297 2.4E-108 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS09770 c2217f395499058bb4ccb8caea4c2b2d 298 Pfam PF00682 HMGL-like 5 275 4.2E-52 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SmaCSM2_RS09770 c2217f395499058bb4ccb8caea4c2b2d 298 SUPERFAMILY SSF51569 1 288 2.64E-71 T 28-03-2018 SmaCSM2_RS06345 604e886e9385720b9cf2097320c192c7 439 PIRSF PIRSF004548 1 438 3.7E-150 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD SmaCSM2_RS06345 604e886e9385720b9cf2097320c192c7 439 Pfam PF06123 Inner membrane protein CreD 6 432 8.0E-149 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD SmaCSM2_RS00895 3b6d65a7d45bf16b73d5d4686ca5e00c 51 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 5.3E-16 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS00895 3b6d65a7d45bf16b73d5d4686ca5e00c 51 PIRSF PIRSF036466 1 51 7.4E-22 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS00895 3b6d65a7d45bf16b73d5d4686ca5e00c 51 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 48 19.371 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 SmaCSM2_RS15745 94a26e217967b66887ae48d7249c92ed 200 SUPERFAMILY SSF109604 12 187 1.26E-17 T 28-03-2018 SmaCSM2_RS15745 94a26e217967b66887ae48d7249c92ed 200 Gene3D G3DSA:1.10.472.50 9 104 4.2E-10 T 28-03-2018 SmaCSM2_RS15745 94a26e217967b66887ae48d7249c92ed 200 PIRSF PIRSF035170 5 200 1.1E-59 T 28-03-2018 IPR009218 Predicted HD phosphohydrolase SmaCSM2_RS18495 b2afbd96075fcc382c546300f40d7678 141 PIRSF PIRSF016789 21 140 2.1E-32 T 28-03-2018 IPR007401 Protein of unknown function DUF454 SmaCSM2_RS18495 b2afbd96075fcc382c546300f40d7678 141 Pfam PF04304 Protein of unknown function (DUF454) 22 135 9.8E-36 T 28-03-2018 IPR007401 Protein of unknown function DUF454 SmaCSM2_RS07465 e6da9b466a7482b1ed3fdab4272f863f 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 87 9.2E-21 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SmaCSM2_RS12475 fedda368e2d787379b069e7bc863cc9e 486 SUPERFAMILY SSF63829 178 289 2.35E-6 T 28-03-2018 SmaCSM2_RS12475 fedda368e2d787379b069e7bc863cc9e 486 Gene3D G3DSA:2.120.10.30 141 388 4.3E-8 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS12475 fedda368e2d787379b069e7bc863cc9e 486 Pfam PF13449 Esterase-like activity of phytase 59 456 4.6E-41 T 28-03-2018 IPR027372 Phytase-like domain SmaCSM2_RS19035 d92eb3107c1b0d076da7395839d7abf9 418 Pfam PF04932 O-Antigen ligase 184 339 2.0E-16 T 28-03-2018 IPR007016 O-antigen ligase-related SmaCSM2_RS10930 8e07aea5e5433f42b261cee6170421ea 316 SUPERFAMILY SSF51230 92 159 4.19E-10 T 28-03-2018 IPR011053 Single hybrid motif SmaCSM2_RS10930 8e07aea5e5433f42b261cee6170421ea 316 Gene3D G3DSA:2.40.50.100 144 300 0.045 T 28-03-2018 SmaCSM2_RS10930 8e07aea5e5433f42b261cee6170421ea 316 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 126 230 6.3E-18 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SmaCSM2_RS10930 8e07aea5e5433f42b261cee6170421ea 316 Gene3D G3DSA:2.40.50.100 90 143 3.8E-14 T 28-03-2018 SmaCSM2_RS10930 8e07aea5e5433f42b261cee6170421ea 316 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 123 303 6.8E-32 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 SmaCSM2_RS00700 0c4cc7d3f847ec9661772f2e49e8ae41 269 SUPERFAMILY SSF69618 20 259 4.58E-44 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS00700 0c4cc7d3f847ec9661772f2e49e8ae41 269 Gene3D G3DSA:3.40.50.10090 53 166 2.8E-23 T 28-03-2018 SmaCSM2_RS00700 0c4cc7d3f847ec9661772f2e49e8ae41 269 Pfam PF02602 Uroporphyrinogen-III synthase HemD 35 257 5.8E-26 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SmaCSM2_RS00700 0c4cc7d3f847ec9661772f2e49e8ae41 269 Gene3D G3DSA:3.40.50.10090 167 264 1.6E-9 T 28-03-2018 SmaCSM2_RS20755 88ee7b80de39cb1ef72f1c3fc4db1e5b 432 Gene3D G3DSA:3.40.50.410 201 392 2.8E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A SmaCSM2_RS20755 88ee7b80de39cb1ef72f1c3fc4db1e5b 432 Pfam PF01882 Protein of unknown function DUF58 189 274 5.0E-22 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SmaCSM2_RS20475 020351e3fea16e4dbf3ae2e6ca4f24c6 359 Gene3D G3DSA:3.40.50.1820 29 359 2.0E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS20475 020351e3fea16e4dbf3ae2e6ca4f24c6 359 PIRSF PIRSF031982 9 359 7.5E-70 T 28-03-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL SmaCSM2_RS20475 020351e3fea16e4dbf3ae2e6ca4f24c6 359 Pfam PF12146 Serine aminopeptidase, S33 95 301 2.2E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SmaCSM2_RS20475 020351e3fea16e4dbf3ae2e6ca4f24c6 359 SUPERFAMILY SSF53474 48 320 2.72E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS19120 85c8dd381b5ba372573c2ac665347ba8 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 423 2.0E-76 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS19120 85c8dd381b5ba372573c2ac665347ba8 454 Pfam PF01554 MatE 249 408 4.9E-28 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS19120 85c8dd381b5ba372573c2ac665347ba8 454 Pfam PF01554 MatE 23 182 3.0E-21 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 SMART SM00155 420 447 6.9E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 SMART SM00155 188 215 7.5E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 SUPERFAMILY SSF56024 276 481 4.04E-31 T 28-03-2018 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 Gene3D G3DSA:3.30.870.10 257 477 1.0E-22 T 28-03-2018 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 Gene3D G3DSA:3.30.870.10 61 256 2.2E-31 T 28-03-2018 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 Pfam PF13091 PLD-like domain 101 247 1.6E-17 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 Pfam PF13091 PLD-like domain 334 473 2.3E-18 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SmaCSM2_RS15820 395882ef50d791f8555e88fab72a9db1 529 SUPERFAMILY SSF56024 58 261 1.63E-44 T 28-03-2018 SmaCSM2_RS06580 8a0c088fc053f39b91962ed9991df805 221 Hamap MF_00052_B Ribonuclease HII [rnhB]. 25 206 34.966 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 SmaCSM2_RS06580 8a0c088fc053f39b91962ed9991df805 221 Gene3D G3DSA:3.30.420.10 9 220 6.9E-62 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06580 8a0c088fc053f39b91962ed9991df805 221 SUPERFAMILY SSF53098 19 212 1.49E-62 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS06580 8a0c088fc053f39b91962ed9991df805 221 Pfam PF01351 Ribonuclease HII 27 205 1.3E-34 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain SmaCSM2_RS20165 c714355fbdaf59500f52a4121e1331e1 352 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 8 337 7.9E-129 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SmaCSM2_RS20165 c714355fbdaf59500f52a4121e1331e1 352 Pfam PF01758 Sodium Bile acid symporter family 53 247 9.8E-63 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SmaCSM2_RS20165 c714355fbdaf59500f52a4121e1331e1 352 PIRSF PIRSF005508 1 352 8.6E-133 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SmaCSM2_RS01150 50300f0687f55b3829f14fa5a050a319 223 Pfam PF02677 Uncharacterized BCR, COG1636 18 192 8.0E-64 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH SmaCSM2_RS01150 50300f0687f55b3829f14fa5a050a319 223 Gene3D G3DSA:3.40.50.620 42 202 3.1E-4 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS11995 ed5e77be9656ed7bf689919ba0ac829e 138 Pfam PF10116 Protein required for attachment to host cells 10 136 9.1E-28 T 28-03-2018 IPR019291 Host attachment protein SmaCSM2_RS11995 ed5e77be9656ed7bf689919ba0ac829e 138 Gene3D G3DSA:3.30.420.60 9 135 6.6E-14 T 28-03-2018 SmaCSM2_RS16125 99d59d1dd1bccfbafc41f5fd92bf1596 61 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 59 1.3E-17 T 28-03-2018 IPR019201 Protein of unknown function DUF2065 SmaCSM2_RS18955 3d336d73c4714085c4da2b49d047f593 143 Pfam PF04940 Sensors of blue-light using FAD 4 93 1.5E-26 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS18955 3d336d73c4714085c4da2b49d047f593 143 SMART SM01034 3 95 3.5E-24 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 SmaCSM2_RS18955 3d336d73c4714085c4da2b49d047f593 143 SUPERFAMILY SSF54975 3 111 1.41E-28 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SmaCSM2_RS15485 3434d31837a43fa3723061bf28f0a8af 414 Pfam PF04235 Protein of unknown function (DUF418) 248 402 2.4E-38 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SmaCSM2_RS13380 c773e7c98a0ecf80551c2fa4d4679caa 107 Pfam PF13827 Domain of unknown function (DUF4189) 9 106 4.1E-11 T 28-03-2018 IPR025240 Domain of unknown function DUF4189 SmaCSM2_RS05150 1da04c61ccf152f0c93b4d75b4a0b158 273 Pfam PF11306 Protein of unknown function (DUF3108) 33 270 6.2E-27 T 28-03-2018 IPR021457 Protein of unknown function DUF3108 SmaCSM2_RS20835 36022cb3afbffa252c4e083d4dc015d2 599 Pfam PF05960 Bacterial protein of unknown function (DUF885) 59 589 1.1E-86 T 28-03-2018 IPR010281 Protein of unknown function DUF885 SmaCSM2_RS09370 019957ed60a1c5eda0b20c29201a390f 94 Pfam PF13828 Domain of unknown function (DUF4190) 11 74 1.1E-22 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 SmaCSM2_RS05730 ead1d96ff7a9ae7c9e6bdb9e5c308c78 211 Pfam PF01810 LysE type translocator 24 208 4.7E-28 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS02745 5ce758c0d108ed4c4f820c84718c9e6d 437 Pfam PF01565 FAD binding domain 34 146 6.5E-22 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SmaCSM2_RS02745 5ce758c0d108ed4c4f820c84718c9e6d 437 Gene3D G3DSA:3.30.465.10 56 182 9.3E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SmaCSM2_RS02745 5ce758c0d108ed4c4f820c84718c9e6d 437 SUPERFAMILY SSF56176 34 178 9.81E-35 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SmaCSM2_RS14540 976565d5f39826f990e0047d789b01be 383 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 380 3.4E-135 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SmaCSM2_RS14540 976565d5f39826f990e0047d789b01be 383 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 11 366 3.3E-107 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SmaCSM2_RS14540 976565d5f39826f990e0047d789b01be 383 PIRSF PIRSF000267 6 382 8.3E-120 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SmaCSM2_RS12645 6c418286eb65d79a5d45acb3745ac50b 107 SUPERFAMILY SSF103481 8 105 1.57E-16 T 28-03-2018 SmaCSM2_RS12645 6c418286eb65d79a5d45acb3745ac50b 107 Pfam PF00893 Small Multidrug Resistance protein 6 96 1.5E-19 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SmaCSM2_RS12200 206fa752c4d2846efa604e9427207627 326 Pfam PF16220 Domain of unknown function (DUF4880) 16 57 1.1E-14 T 28-03-2018 IPR032623 FecR, N-terminal SmaCSM2_RS12200 206fa752c4d2846efa604e9427207627 326 Pfam PF16344 Domain of unknown function (DUF4974) 225 314 1.6E-8 T 28-03-2018 IPR032508 Protein FecR, C-terminal SmaCSM2_RS12200 206fa752c4d2846efa604e9427207627 326 Pfam PF04773 FecR protein 123 214 1.1E-8 T 28-03-2018 IPR006860 FecR protein SmaCSM2_RS12200 206fa752c4d2846efa604e9427207627 326 PIRSF PIRSF018266 6 325 2.2E-56 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component SmaCSM2_RS05600 d2cf0105798dd67ef2a19dc352f1c180 212 Pfam PF01794 Ferric reductase like transmembrane component 51 160 2.2E-7 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain SmaCSM2_RS04190 0d346d3efc94ead94b81711241ce6ca8 203 Gene3D G3DSA:3.40.30.10 1 95 4.6E-22 T 28-03-2018 SmaCSM2_RS04190 0d346d3efc94ead94b81711241ce6ca8 203 Gene3D G3DSA:1.20.1050.10 96 198 4.8E-20 T 28-03-2018 SmaCSM2_RS04190 0d346d3efc94ead94b81711241ce6ca8 203 SUPERFAMILY SSF47616 83 201 3.48E-22 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SmaCSM2_RS04190 0d346d3efc94ead94b81711241ce6ca8 203 SUPERFAMILY SSF52833 1 78 3.66E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS04190 0d346d3efc94ead94b81711241ce6ca8 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 70 6.0E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SmaCSM2_RS12070 914867ea3307b8fece83c5177482f2f5 213 Pfam PF00857 Isochorismatase family 21 173 1.1E-21 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12070 914867ea3307b8fece83c5177482f2f5 213 Gene3D G3DSA:3.40.50.850 10 211 9.1E-30 T 28-03-2018 SmaCSM2_RS12070 914867ea3307b8fece83c5177482f2f5 213 SUPERFAMILY SSF52499 12 199 4.32E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS01295 283f3d42e05430b4be350f81c807121b 288 Pfam PF07007 Lysozyme inhibitor LprI 193 281 1.0E-4 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal SmaCSM2_RS01295 283f3d42e05430b4be350f81c807121b 288 Pfam PF07007 Lysozyme inhibitor LprI 93 170 3.3E-4 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 Gene3D G3DSA:1.10.10.10 75 161 1.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 Gene3D G3DSA:1.10.1740.10 3 74 2.4E-7 T 28-03-2018 SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 159 2.6E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 SUPERFAMILY SSF88659 99 161 2.03E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 SUPERFAMILY SSF88946 6 87 1.02E-6 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS12050 edb3600b09048d07477733deb2cac7d0 167 Pfam PF08281 Sigma-70, region 4 106 154 5.0E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SmaCSM2_RS17580 11c6def2e5acb3a41fd035383067608a 168 Pfam PF11066 Protein of unknown function (DUF2867) 21 158 5.2E-35 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 8.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 SMART SM00387 341 450 2.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 448 2.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 SUPERFAMILY SSF55874 319 448 9.82E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 Gene3D G3DSA:1.10.287.130 228 303 0.0015 T 28-03-2018 SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 Gene3D G3DSA:3.30.565.10 305 450 2.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SmaCSM2_RS18665 f6f24afc0f9c14463167dec0d5faf805 450 SUPERFAMILY SSF47384 233 307 2.55E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SmaCSM2_RS17115 35935863ce3775a6fefe98b6aa782f82 143 Pfam PF11162 Protein of unknown function (DUF2946) 14 137 1.5E-11 T 28-03-2018 IPR021333 Protein of unknown function DUF2946 SmaCSM2_RS16760 0ae31727f68878894e4248d018059c26 409 Pfam PF00999 Sodium/hydrogen exchanger family 9 367 5.1E-22 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS16760 0ae31727f68878894e4248d018059c26 409 Gene3D G3DSA:1.20.91.10 214 310 2.7E-6 T 28-03-2018 SmaCSM2_RS10850 1f0bf3131b6f2850bb04e7a464d02f6c 309 Pfam PF05425 Copper resistance protein D 198 303 7.3E-24 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 SmaCSM2_RS14210 07cc5b606545c427501de225beb4a7f7 275 Pfam PF00899 ThiF family 19 173 1.7E-38 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SmaCSM2_RS14210 07cc5b606545c427501de225beb4a7f7 275 Gene3D G3DSA:3.40.50.720 1 269 4.3E-49 T 28-03-2018 SmaCSM2_RS14210 07cc5b606545c427501de225beb4a7f7 275 SUPERFAMILY SSF69572 7 261 9.55E-59 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SmaCSM2_RS04630 10f33920d6c7ad69981a73e94c1d025c 306 Pfam PF16162 Domain of unknown function (DUF4868) 109 293 4.5E-40 T 28-03-2018 IPR032359 Protein of unknown function DUF4868 SmaCSM2_RS00930 99bbf45d1b4e98b0b4640560bd9c2253 203 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 119 7.8E-23 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SmaCSM2_RS00930 99bbf45d1b4e98b0b4640560bd9c2253 203 SUPERFAMILY SSF102588 4 202 2.35E-45 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SmaCSM2_RS00930 99bbf45d1b4e98b0b4640560bd9c2253 203 Gene3D G3DSA:3.40.50.10320 2 203 9.6E-44 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SmaCSM2_RS02445 b2f6527e9f5dd11f26f770c8a70df9f5 96 Pfam PF11607 Protein of unknown function (DUF3247) 1 92 6.5E-44 T 28-03-2018 IPR021649 Protein of unknown function DUF3247 SmaCSM2_RS03435 7c8883c0eb59efce263f1f77d7a2ce42 64 Pfam PF10636 Hemin uptake protein hemP 28 64 1.3E-18 T 28-03-2018 IPR019600 Hemin uptake protein HemP SmaCSM2_RS03435 7c8883c0eb59efce263f1f77d7a2ce42 64 Gene3D G3DSA:2.10.70.10 28 64 2.4E-18 T 28-03-2018 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 SUPERFAMILY SSF48498 78 190 9.64E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 SUPERFAMILY SSF46689 8 82 5.67E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 Gene3D G3DSA:1.10.10.60 6 53 3.6E-15 T 28-03-2018 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 Gene3D G3DSA:1.10.357.10 54 192 7.2E-19 T 28-03-2018 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS09225 c0fe3ef0b996d5145b2b40ab6b23f0fa 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 1.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 357 2.3E-125 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 Gene3D G3DSA:2.40.50.140 29 112 6.0E-7 T 28-03-2018 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 6 443 29.735 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 Gene3D G3DSA:3.90.226.10 176 439 0.037 T 28-03-2018 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 Pfam PF13742 OB-fold nucleic acid binding domain 13 102 8.4E-26 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SmaCSM2_RS14780 61fa69856f970dd22c19d099dc60962e 443 Pfam PF02601 Exonuclease VII, large subunit 125 440 7.6E-91 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SmaCSM2_RS15130 b5214c357c4624e5cda7af1b99b626c3 218 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 20 167 2.4E-36 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SmaCSM2_RS14545 9cd284952c912008cd73632193982efd 38 Pfam PF08173 Membrane bound YbgT-like protein 1 27 3.0E-15 T 28-03-2018 IPR012994 Membrane bound YbgT-like SmaCSM2_RS14545 9cd284952c912008cd73632193982efd 38 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 2.3E-17 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 SmaCSM2_RS13625 fa970a65860a444555cf6f0c7a92a694 214 SUPERFAMILY SSF74653 134 211 1.22E-23 T 28-03-2018 SmaCSM2_RS13625 fa970a65860a444555cf6f0c7a92a694 214 Gene3D G3DSA:3.30.1150.10 48 214 3.2E-22 T 28-03-2018 SmaCSM2_RS13625 fa970a65860a444555cf6f0c7a92a694 214 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 137 213 7.6E-23 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS13625 fa970a65860a444555cf6f0c7a92a694 214 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 135 212 3.0E-25 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS20105 4f2149b93ce23bb9826cb4edad4f40e4 253 Pfam PF01925 Sulfite exporter TauE/SafE 9 248 9.4E-49 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SmaCSM2_RS08645 e4bd3db81ada41ebe0af4c0efb3ab4e4 290 Pfam PF01965 DJ-1/PfpI family 77 198 4.4E-7 T 28-03-2018 IPR002818 DJ-1/PfpI SmaCSM2_RS08645 e4bd3db81ada41ebe0af4c0efb3ab4e4 290 Gene3D G3DSA:3.40.50.880 2 289 4.2E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS08645 e4bd3db81ada41ebe0af4c0efb3ab4e4 290 PIRSF PIRSF037798 1 290 4.3E-140 T 28-03-2018 IPR017283 Protein deglycase HchA SmaCSM2_RS08645 e4bd3db81ada41ebe0af4c0efb3ab4e4 290 SUPERFAMILY SSF52317 8 284 3.25E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS06130 a563cde0093e71f545df67b30550352c 130 Gene3D G3DSA:3.30.370.10 3 125 3.6E-15 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SmaCSM2_RS07585 a410d4c02880b7ebc9e908ce9f240ca0 301 Pfam PF11920 Protein of unknown function (DUF3438) 9 284 2.3E-126 T 28-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 SmaCSM2_RS07585 a410d4c02880b7ebc9e908ce9f240ca0 301 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 13 275 7.8E-114 T 28-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 SmaCSM2_RS10835 8b2eae7e6be265efa8bc554b0f49491b 183 Gene3D G3DSA:1.20.1260.10 2 182 5.2E-25 T 28-03-2018 IPR012347 Ferritin-related SmaCSM2_RS10835 8b2eae7e6be265efa8bc554b0f49491b 183 Pfam PF03713 Domain of unknown function (DUF305) 125 178 1.1E-13 T 28-03-2018 IPR005183 Domain of unknown function DUF305 SmaCSM2_RS20970 ff646f2e84123eae3edae66b7e4b3742 285 Gene3D G3DSA:3.40.50.150 37 281 3.4E-20 T 28-03-2018 SmaCSM2_RS20970 ff646f2e84123eae3edae66b7e4b3742 285 PIRSF PIRSF031679 11 285 1.2E-103 T 28-03-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted SmaCSM2_RS20970 ff646f2e84123eae3edae66b7e4b3742 285 SUPERFAMILY SSF53335 68 242 1.4E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS15725 33a77b32b88277f46e8b0095f61b1471 854 Gene3D G3DSA:3.40.630.30 644 823 1.1E-17 T 28-03-2018 SmaCSM2_RS15725 33a77b32b88277f46e8b0095f61b1471 854 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 542 829 2.3E-92 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SmaCSM2_RS15725 33a77b32b88277f46e8b0095f61b1471 854 SUPERFAMILY SSF55729 649 827 1.46E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SmaCSM2_RS15255 274f693a8d5bd64fd5aa85208c4a2bd6 369 Pfam PF05816 Toxic anion resistance protein (TelA) 49 364 2.5E-71 T 28-03-2018 IPR008863 Toxic anion resistance SmaCSM2_RS15255 274f693a8d5bd64fd5aa85208c4a2bd6 369 PIRSF PIRSF026508 12 369 4.5E-92 T 28-03-2018 IPR008863 Toxic anion resistance SmaCSM2_RS06055 5e696288df830a7d43f2821491fcddbf 358 SUPERFAMILY SSF51412 14 333 1.05E-48 T 28-03-2018 SmaCSM2_RS06055 5e696288df830a7d43f2821491fcddbf 358 Pfam PF03060 Nitronate monooxygenase 21 345 1.6E-59 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SmaCSM2_RS06055 5e696288df830a7d43f2821491fcddbf 358 Gene3D G3DSA:3.20.20.70 1 358 1.2E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS07030 29410f14a2611a1baac7862e29f0e215 253 Gene3D G3DSA:3.40.50.880 2 253 1.7E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS07030 29410f14a2611a1baac7862e29f0e215 253 SUPERFAMILY SSF52317 27 247 3.48E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS07030 29410f14a2611a1baac7862e29f0e215 253 Pfam PF07722 Peptidase C26 5 222 1.5E-64 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 SmaCSM2_RS12180 8cc00570bbbbef8041535062a6fb8319 301 Gene3D G3DSA:3.30.1300.30 34 139 1.4E-7 T 28-03-2018 SmaCSM2_RS12180 8cc00570bbbbef8041535062a6fb8319 301 Pfam PF03934 Type II secretion system (T2SS), protein K 38 285 2.0E-33 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 SmaCSM2_RS12180 8cc00570bbbbef8041535062a6fb8319 301 PIRSF PIRSF002786 9 300 5.4E-35 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 SmaCSM2_RS10755 7cef31b158ba8714dc2200c0fb66c817 988 Pfam PF01526 Tn3 transposase DDE domain 580 966 5.1E-154 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 SmaCSM2_RS10755 7cef31b158ba8714dc2200c0fb66c817 988 Pfam PF13700 Domain of unknown function (DUF4158) 6 169 2.0E-53 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 SmaCSM2_RS15050 3b2b88ca57f248d83e64fd8d26a04e07 519 Pfam PF03929 PepSY-associated TM region 13 368 1.5E-51 T 28-03-2018 IPR005625 PepSY-associated TM protein SmaCSM2_RS04860 c5cf5438ed5235633eae4592cd74ac13 131 Pfam PF11162 Protein of unknown function (DUF2946) 3 126 3.0E-5 T 28-03-2018 IPR021333 Protein of unknown function DUF2946 SmaCSM2_RS21145 b56a0a2ce89942ba73ec22abcd4c2b26 247 SUPERFAMILY SSF53901 36 160 6.48E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS21145 b56a0a2ce89942ba73ec22abcd4c2b26 247 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 22 243 3.4E-69 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SmaCSM2_RS21145 b56a0a2ce89942ba73ec22abcd4c2b26 247 Gene3D G3DSA:3.40.47.10 7 175 8.4E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SmaCSM2_RS18160 85162adb93016246d6d79de600160705 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 128 3.9E-14 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 SmaCSM2_RS17330 ec1b0f34ed6606fa8e1ff55e41e93e99 169 Pfam PF04449 CS1 type fimbrial major subunit 24 163 7.7E-41 T 28-03-2018 IPR007540 Fimbrial major subunit, CS1-type GO:0009289 SmaCSM2_RS00380 099a8ee767529b3620b8ba41e930b2b1 309 SUPERFAMILY SSF52402 31 249 2.72E-56 T 28-03-2018 SmaCSM2_RS00380 099a8ee767529b3620b8ba41e930b2b1 309 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 23 284 55.623 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 SmaCSM2_RS00380 099a8ee767529b3620b8ba41e930b2b1 309 PIRSF PIRSF004976 12 285 1.5E-72 T 28-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 SmaCSM2_RS00380 099a8ee767529b3620b8ba41e930b2b1 309 Pfam PF01171 PP-loop family 54 218 4.5E-17 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SmaCSM2_RS00380 099a8ee767529b3620b8ba41e930b2b1 309 Gene3D G3DSA:3.40.50.620 21 252 5.7E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS17755 2d9852ee244418a6d826f2d4bc628162 363 Gene3D G3DSA:3.40.50.1100 39 143 1.6E-28 T 28-03-2018 SmaCSM2_RS17755 2d9852ee244418a6d826f2d4bc628162 363 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 292 5.2E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS17755 2d9852ee244418a6d826f2d4bc628162 363 Gene3D G3DSA:3.40.50.1100 144 316 1.9E-33 T 28-03-2018 SmaCSM2_RS17755 2d9852ee244418a6d826f2d4bc628162 363 SUPERFAMILY SSF53686 16 308 2.1E-76 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SmaCSM2_RS02715 efb48c94b7984ff25bbc3bb34aa5f99f 133 Pfam PF04138 GtrA-like protein 8 127 1.2E-19 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SmaCSM2_RS11375 78fa30bec4b577ec8899b998b87853e0 289 Pfam PF02219 Methylenetetrahydrofolate reductase 47 228 6.8E-11 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SmaCSM2_RS11375 78fa30bec4b577ec8899b998b87853e0 289 SUPERFAMILY SSF51730 16 281 3.14E-42 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS11375 78fa30bec4b577ec8899b998b87853e0 289 Gene3D G3DSA:3.20.20.220 8 286 3.5E-49 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SmaCSM2_RS01250 b5cb8879e5c526d4d3801d4233b0cbc2 109 Pfam PF05939 Phage minor tail protein 3 106 1.2E-30 T 28-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail SmaCSM2_RS04345 a4caf75a7aacec2d94596910983530b6 130 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 48 95 5.4E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS04345 a4caf75a7aacec2d94596910983530b6 130 SUPERFAMILY SSF69118 5 112 5.37E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS04345 a4caf75a7aacec2d94596910983530b6 130 Pfam PF02627 Carboxymuconolactone decarboxylase family 32 112 7.3E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SmaCSM2_RS04345 a4caf75a7aacec2d94596910983530b6 130 Gene3D G3DSA:1.20.1290.10 1 129 5.3E-21 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SmaCSM2_RS19865 4e5c62237591e03e7b884461a18ed42c 308 PIRSF PIRSF016660 1 308 4.0E-113 T 28-03-2018 IPR008526 Inner membrane protein YedI SmaCSM2_RS19865 4e5c62237591e03e7b884461a18ed42c 308 Pfam PF05661 Protein of unknown function (DUF808) 4 297 1.7E-110 T 28-03-2018 IPR008526 Inner membrane protein YedI SmaCSM2_RS13855 262daefdaa988bd025f0bf85a6459da2 242 Pfam PF11218 Protein of unknown function (DUF3011) 37 239 4.5E-87 T 28-03-2018 IPR021381 Protein of unknown function DUF3011 SmaCSM2_RS18625 60d38c95d970bd5850bc710ff84d5ed1 436 Pfam PF12704 MacB-like periplasmic core domain 20 268 7.8E-15 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SmaCSM2_RS18625 60d38c95d970bd5850bc710ff84d5ed1 436 Pfam PF02687 FtsX-like permease family 340 429 9.5E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS06195 2f594f24bc066b308aa636947b8ac75e 204 Pfam PF01810 LysE type translocator 16 201 4.4E-38 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SmaCSM2_RS08985 ee78ce2326ef943bdf0f62a998c4d445 225 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 33.216 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SmaCSM2_RS08985 ee78ce2326ef943bdf0f62a998c4d445 225 Pfam PF02224 Cytidylate kinase 9 219 2.3E-70 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SmaCSM2_RS08985 ee78ce2326ef943bdf0f62a998c4d445 225 Gene3D G3DSA:3.40.50.300 4 222 2.6E-44 T 28-03-2018 SmaCSM2_RS08985 ee78ce2326ef943bdf0f62a998c4d445 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 217 5.2E-72 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SmaCSM2_RS08985 ee78ce2326ef943bdf0f62a998c4d445 225 SUPERFAMILY SSF52540 6 220 5.69E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19355 ed60e908f3df41b56475fbbf9217e423 255 Pfam PF11906 Protein of unknown function (DUF3426) 111 254 4.9E-32 T 28-03-2018 IPR021834 Protein of unknown function DUF3426 SmaCSM2_RS04560 fc48e63434fac48d50a571a0379f5759 296 Pfam PF00482 Type II secretion system (T2SS), protein F 156 282 5.8E-21 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS13275 fcfa705cc301c1dc9db87057e2091500 205 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 9 199 3.6E-75 T 28-03-2018 IPR018715 Protein of unknown function DUF2239 SmaCSM2_RS17585 d91466003c6cf313e6531bba4d0f0169 220 Gene3D G3DSA:3.90.1200.10 40 202 5.7E-14 T 28-03-2018 SmaCSM2_RS17585 d91466003c6cf313e6531bba4d0f0169 220 SUPERFAMILY SSF56112 40 149 5.33E-15 T 28-03-2018 IPR011009 Protein kinase-like domain SmaCSM2_RS11500 7398a45f8695f5307321c0baad81d071 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 128 1.5E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SmaCSM2_RS11500 7398a45f8695f5307321c0baad81d071 141 SUPERFAMILY SSF54593 2 132 4.03E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS11500 7398a45f8695f5307321c0baad81d071 141 Gene3D G3DSA:3.10.180.10 1 137 3.6E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SmaCSM2_RS07070 8cbedb7e025040927701c9a2943986a9 422 Pfam PF13387 Domain of unknown function (DUF4105) 57 188 2.6E-16 T 28-03-2018 IPR025178 Domain of unknown function DUF4105 SmaCSM2_RS07580 da84c3f2d2f8aef2aa0a4f0b6ba22491 472 Gene3D G3DSA:1.20.1170.10 42 398 5.8E-8 T 28-03-2018 SmaCSM2_RS07580 da84c3f2d2f8aef2aa0a4f0b6ba22491 472 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 2 462 4.1E-188 T 28-03-2018 IPR021207 Integrating conjugative element protein, PFL4705 SmaCSM2_RS07710 54403627d055bfc31825967f7f3d2370 117 Pfam PF11284 Protein of unknown function (DUF3085) 22 111 7.2E-33 T 28-03-2018 IPR021436 Protein of unknown function DUF3085 SmaCSM2_RS12995 00aa5e6725cceb36f93642f6e8b1a868 469 SUPERFAMILY SSF56672 1 227 3.56E-31 T 28-03-2018 SmaCSM2_RS12995 00aa5e6725cceb36f93642f6e8b1a868 469 Gene3D G3DSA:1.10.150.20 159 232 0.0025 T 28-03-2018 SmaCSM2_RS12995 00aa5e6725cceb36f93642f6e8b1a868 469 Pfam PF00817 impB/mucB/samB family 24 148 1.0E-6 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SmaCSM2_RS04290 8cbe9d61a6c58e10a47c639c134fa178 417 Gene3D G3DSA:3.40.390.10 192 390 4.0E-12 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SmaCSM2_RS04290 8cbe9d61a6c58e10a47c639c134fa178 417 Pfam PF13688 Metallo-peptidase family M12 197 383 6.6E-25 T 28-03-2018 SmaCSM2_RS04290 8cbe9d61a6c58e10a47c639c134fa178 417 SUPERFAMILY SSF55486 195 388 1.66E-15 T 28-03-2018 SmaCSM2_RS08225 f71a0818aadbfd18b0c297645b247441 372 SUPERFAMILY SSF53474 60 348 1.07E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS08225 f71a0818aadbfd18b0c297645b247441 372 Pfam PF12697 Alpha/beta hydrolase family 119 331 4.0E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SmaCSM2_RS08225 f71a0818aadbfd18b0c297645b247441 372 Gene3D G3DSA:3.40.50.1820 47 352 6.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS09970 7a4c3ae850a283ce2658451535cde6b3 495 Gene3D G3DSA:3.40.50.1820 5 493 7.1E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS09970 7a4c3ae850a283ce2658451535cde6b3 495 SUPERFAMILY SSF53474 26 176 8.79E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 Gene3D G3DSA:3.40.50.2300 13 135 2.2E-20 T 28-03-2018 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 Pfam PF00072 Response regulator receiver domain 16 129 4.0E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 Pfam PF00072 Response regulator receiver domain 143 264 2.2E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 SUPERFAMILY SSF52172 139 275 8.68E-24 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 SMART SM00448 141 264 3.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 SMART SM00448 14 129 2.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 Gene3D G3DSA:3.40.50.2300 136 274 4.9E-23 T 28-03-2018 SmaCSM2_RS19430 c02d74c9ec0ebbf699c1accb6edd008d 280 SUPERFAMILY SSF52172 14 134 7.26E-21 T 28-03-2018 IPR011006 CheY-like superfamily SmaCSM2_RS14360 d2bb76f0de998e23c097a25155269fce 269 Hamap MF_00548 Zinc transporter ZupT [zupT]. 9 268 33.188 T 28-03-2018 IPR023498 Zinc transporter ZupT SmaCSM2_RS14360 d2bb76f0de998e23c097a25155269fce 269 Pfam PF02535 ZIP Zinc transporter 121 261 6.5E-21 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 SmaCSM2_RS13325 d75c2e683e18f2518a2df97da4226b2c 119 Gene3D G3DSA:1.10.10.10 4 119 2.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS13325 d75c2e683e18f2518a2df97da4226b2c 119 Pfam PF01638 HxlR-like helix-turn-helix 20 107 2.5E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SmaCSM2_RS13325 d75c2e683e18f2518a2df97da4226b2c 119 SUPERFAMILY SSF46785 7 117 1.89E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SmaCSM2_RS20035 14bf7b222affa7f3537fa9e6e0995a30 200 Pfam PF06197 Protein of unknown function (DUF998) 17 184 2.4E-15 T 28-03-2018 IPR009339 Protein of unknown function DUF998 SmaCSM2_RS00490 b699a45f5be9abe4a74f426face4b4de 602 Gene3D G3DSA:3.40.50.880 235 485 2.6E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS00490 b699a45f5be9abe4a74f426face4b4de 602 SUPERFAMILY SSF52317 251 459 8.47E-6 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SmaCSM2_RS05245 8e26a4cfdec259c32bc36ddf7d9cfb3f 267 Pfam PF10670 Domain of unknown function (DUF4198) 19 242 2.5E-67 T 28-03-2018 IPR019613 Protein of unknown function DUF4198 SmaCSM2_RS19170 c2459a265995fe0794b0ae9a84017272 205 Pfam PF03458 UPF0126 domain 5 78 8.8E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SmaCSM2_RS19170 c2459a265995fe0794b0ae9a84017272 205 Pfam PF03458 UPF0126 domain 91 163 1.4E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SmaCSM2_RS14295 45d8954865df7e0b06b9df8f42dace38 293 Gene3D G3DSA:3.30.565.40 58 173 5.9E-9 T 28-03-2018 SmaCSM2_RS14295 45d8954865df7e0b06b9df8f42dace38 293 Pfam PF13739 Domain of unknown function (DUF4163) 97 156 6.6E-7 T 28-03-2018 IPR025303 Deacetylase PdaC SmaCSM2_RS14295 45d8954865df7e0b06b9df8f42dace38 293 Gene3D G3DSA:3.90.640.20 176 291 2.2E-16 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 SmaCSM2_RS14295 45d8954865df7e0b06b9df8f42dace38 293 Pfam PF11738 Protein of unknown function (DUF3298) 185 275 1.2E-5 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 SmaCSM2_RS06145 0dcbf033536c54f720c4e5c267539a5c 291 Pfam PF10947 Protein of unknown function (DUF2628) 51 128 1.9E-8 T 28-03-2018 IPR024399 Protein of unknown function DUF2628 SmaCSM2_RS00925 7079f22693cc0e8e39aae245b5e9d31d 379 SUPERFAMILY SSF53448 26 285 6.44E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS00925 7079f22693cc0e8e39aae245b5e9d31d 379 Pfam PF00535 Glycosyl transferase family 2 34 201 4.1E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SmaCSM2_RS00925 7079f22693cc0e8e39aae245b5e9d31d 379 Gene3D G3DSA:3.90.550.10 18 274 7.4E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SmaCSM2_RS02995 edf079d7c7f9c37b7b97c1309c30775b 381 SUPERFAMILY SSF53067 78 176 1.2E-8 T 28-03-2018 SmaCSM2_RS02995 edf079d7c7f9c37b7b97c1309c30775b 381 Pfam PF05137 Fimbrial assembly protein (PilN) 287 359 3.1E-9 T 28-03-2018 IPR007813 Fimbrial assembly PilN SmaCSM2_RS12805 26e58a63f3ee5f3e9bdaf5922ee3cd6f 218 SUPERFAMILY SSF52499 9 209 5.23E-48 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12805 26e58a63f3ee5f3e9bdaf5922ee3cd6f 218 Pfam PF00857 Isochorismatase family 19 169 6.3E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SmaCSM2_RS12805 26e58a63f3ee5f3e9bdaf5922ee3cd6f 218 Gene3D G3DSA:3.40.50.850 8 213 1.3E-36 T 28-03-2018 SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Pfam PF08238 Sel1 repeat 37 70 6.4E-5 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Pfam PF08238 Sel1 repeat 111 143 5.4E-6 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Pfam PF08238 Sel1 repeat 144 179 1.2E-7 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Pfam PF08238 Sel1 repeat 72 104 2.0E-6 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Pfam PF08238 Sel1 repeat 196 211 2.9 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SUPERFAMILY SSF81901 12 217 3.58E-45 T 28-03-2018 SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Gene3D G3DSA:1.25.40.10 155 229 5.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Gene3D G3DSA:2.60.40.1180 9 105 3.1E-20 T 28-03-2018 SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 Gene3D G3DSA:2.60.40.1180 106 154 2.8E-11 T 28-03-2018 SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SMART SM00671 72 107 2.8E-7 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SMART SM00671 144 179 1.5E-6 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SMART SM00671 110 143 7.3E-5 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SMART SM00671 36 71 4.0E-6 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS05275 80810832b8ee393b6ddbbf95a5c433ed 239 SMART SM00671 180 211 89.0 T 28-03-2018 IPR006597 Sel1-like repeat SmaCSM2_RS02915 8b14e157aac20bf0e3ba2270fae925ef 163 Pfam PF06271 RDD family 21 154 9.8E-22 T 28-03-2018 IPR010432 RDD SmaCSM2_RS14535 85b75884daa4aad75966fbae8a23b043 529 PIRSF PIRSF006446 2 321 4.4E-113 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SmaCSM2_RS14535 85b75884daa4aad75966fbae8a23b043 529 PIRSF PIRSF006446 360 526 1.2E-35 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SmaCSM2_RS14535 85b75884daa4aad75966fbae8a23b043 529 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 2.8E-178 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SmaCSM2_RS09750 575dede826080113e717811fb442f155 231 SUPERFAMILY SSF141488 49 123 1.96E-13 T 28-03-2018 IPR018660 C-type lysozyme inhibitor SmaCSM2_RS09750 575dede826080113e717811fb442f155 231 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 52 116 3.8E-13 T 28-03-2018 IPR018660 C-type lysozyme inhibitor SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 22 277 1.7E-98 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 Gene3D G3DSA:3.20.20.20 159 282 4.1E-46 T 28-03-2018 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 Gene3D G3DSA:3.20.20.20 19 158 2.4E-62 T 28-03-2018 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 22 37 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 56 69 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 SUPERFAMILY SSF51717 12 279 6.28E-100 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS08110 fca0a756e431b112400aa8c9752b2ef3 298 Pfam PF00809 Pterin binding enzyme 23 263 1.3E-82 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SmaCSM2_RS06245 00125cdd49f68971a1978a291ac11d5d 119 Pfam PF00892 EamA-like transporter family 42 115 1.0E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS06245 00125cdd49f68971a1978a291ac11d5d 119 SUPERFAMILY SSF103481 39 117 3.01E-11 T 28-03-2018 SmaCSM2_RS15775 eb5ccefafd36126f90697b81e871b307 293 Pfam PF13349 Putative adhesin 66 290 3.3E-13 T 28-03-2018 IPR025164 Putative adhesin SmaCSM2_RS00970 db73fb7eb0a5c69dac176ae0024a3e34 148 SUPERFAMILY SSF52304 1 135 6.28E-14 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS00970 db73fb7eb0a5c69dac176ae0024a3e34 148 Gene3D G3DSA:3.40.50.9100 1 138 1.3E-10 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SmaCSM2_RS01105 48750fb08c6cdd7bc7ed1cebc4da227b 339 SUPERFAMILY SSF47240 6 326 9.27E-86 T 28-03-2018 IPR009078 Ferritin-like superfamily SmaCSM2_RS01105 48750fb08c6cdd7bc7ed1cebc4da227b 339 PIRSF PIRSF000355 3 337 5.6E-96 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS01105 48750fb08c6cdd7bc7ed1cebc4da227b 339 Gene3D G3DSA:1.10.620.20 2 313 2.0E-86 T 28-03-2018 SmaCSM2_RS01105 48750fb08c6cdd7bc7ed1cebc4da227b 339 Pfam PF00268 Ribonucleotide reductase, small chain 17 302 3.0E-78 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SmaCSM2_RS18480 3f70541a26395b5b32a4619faa540eb8 224 Gene3D G3DSA:3.30.450.40 42 221 1.9E-8 T 28-03-2018 IPR029016 GAF domain-like SmaCSM2_RS18480 3f70541a26395b5b32a4619faa540eb8 224 Pfam PF04340 Protein of unknown function, DUF484 4 223 3.7E-65 T 28-03-2018 IPR007435 Protein of unknown function DUF484 SmaCSM2_RS01515 f6988a92e9c4fc7d0621ef917e187bbd 156 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 29 132 2.0E-6 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III SmaCSM2_RS12745 c1a66dbab5fbfe835389977045c38df0 318 Pfam PF00482 Type II secretion system (T2SS), protein F 151 274 1.3E-13 T 28-03-2018 IPR018076 Type II secretion system F domain SmaCSM2_RS07085 10ca1e9d99a8c8f739d9132ed005f692 201 Gene3D G3DSA:3.30.300.50 36 111 3.1E-4 T 28-03-2018 IPR035070 Streptogrisin prodomain SmaCSM2_RS09495 0f8fb5c0a34643568bcca350e51411cd 316 SUPERFAMILY SSF103481 48 144 6.02E-8 T 28-03-2018 SmaCSM2_RS09495 0f8fb5c0a34643568bcca350e51411cd 316 Pfam PF00892 EamA-like transporter family 8 141 1.1E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS09495 0f8fb5c0a34643568bcca350e51411cd 316 Pfam PF00892 EamA-like transporter family 160 300 3.5E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS15370 fbe59d42c65f89d78977f3f5337d4d97 131 SUPERFAMILY SSF54001 7 129 1.57E-5 T 28-03-2018 SmaCSM2_RS15370 fbe59d42c65f89d78977f3f5337d4d97 131 Gene3D G3DSA:3.90.1720.10 6 119 3.5E-7 T 28-03-2018 SmaCSM2_RS16755 1ecd0813a9b3b27687de3821e4f10687 518 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 80 247 1.5E-9 T 28-03-2018 SmaCSM2_RS14675 598c0b8360d03753beb948ab1ea70e00 234 Gene3D G3DSA:1.10.600.10 3 136 7.5E-7 T 28-03-2018 IPR008949 Isoprenoid synthase domain SmaCSM2_RS02650 cf67d8fd7823896a2da91f13ff007ba1 294 SUPERFAMILY SSF103088 206 279 2.75E-7 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS02650 cf67d8fd7823896a2da91f13ff007ba1 294 Gene3D G3DSA:3.30.1330.60 182 289 2.9E-8 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS02650 cf67d8fd7823896a2da91f13ff007ba1 294 Pfam PF00691 OmpA family 210 280 7.2E-5 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS01500 f8f5a7fe4cd3e763ab29c785ccba96d2 239 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 199 5.4E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS01500 f8f5a7fe4cd3e763ab29c785ccba96d2 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 65 198 1.3E-11 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01500 f8f5a7fe4cd3e763ab29c785ccba96d2 239 SUPERFAMILY SSF56784 5 228 3.54E-43 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01500 f8f5a7fe4cd3e763ab29c785ccba96d2 239 Gene3D G3DSA:3.40.50.1000 89 236 1.0E-26 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS01500 f8f5a7fe4cd3e763ab29c785ccba96d2 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 193 2.1E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SmaCSM2_RS05610 8fb910b63cd5aefbeb2b912e3c8a4a50 281 SUPERFAMILY SSF51658 30 249 1.74E-12 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SmaCSM2_RS05610 8fb910b63cd5aefbeb2b912e3c8a4a50 281 Gene3D G3DSA:3.20.20.150 6 280 2.4E-81 T 28-03-2018 SmaCSM2_RS05610 8fb910b63cd5aefbeb2b912e3c8a4a50 281 Hamap MF_00697 UPF0276 protein . 10 278 45.145 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 SmaCSM2_RS05610 8fb910b63cd5aefbeb2b912e3c8a4a50 281 Pfam PF05114 Protein of unknown function (DUF692) 10 270 1.5E-102 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 SmaCSM2_RS16030 aaa5b342f86d96d2d2a9143051ccfbf7 567 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 218 4.0E-16 T 28-03-2018 SmaCSM2_RS11100 adc0e6338cba47e7cba91fa5b7c9316e 531 Gene3D G3DSA:3.30.420.10 103 335 8.3E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SmaCSM2_RS20925 3b97dd6527e4eb3f014374eb9ad14ee2 263 PIRSF PIRSF006648 1 260 2.8E-26 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS20925 3b97dd6527e4eb3f014374eb9ad14ee2 263 Pfam PF01061 ABC-2 type transporter 16 225 3.9E-35 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SmaCSM2_RS20925 3b97dd6527e4eb3f014374eb9ad14ee2 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 65 87 1.6E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS20925 3b97dd6527e4eb3f014374eb9ad14ee2 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 183 202 1.6E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS20925 3b97dd6527e4eb3f014374eb9ad14ee2 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 109 134 1.6E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SmaCSM2_RS06620 4b18bd456cad18048438d75c37b8feab 278 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 234 260 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 SmaCSM2_RS06620 4b18bd456cad18048438d75c37b8feab 278 Pfam PF01148 Cytidylyltransferase family 3 275 8.2E-67 T 28-03-2018 SmaCSM2_RS18450 346af603d6ab185f0f9579b509d96900 169 PIRSF PIRSF032285 2 168 6.8E-57 T 28-03-2018 IPR011235 MepB-like SmaCSM2_RS18450 346af603d6ab185f0f9579b509d96900 169 Pfam PF08877 MepB protein 29 150 3.5E-43 T 28-03-2018 IPR011235 MepB-like SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 Gene3D G3DSA:3.30.1330.60 140 278 3.0E-30 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 SUPERFAMILY SSF103088 158 273 1.83E-29 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 Pfam PF00691 OmpA family 167 259 7.8E-21 T 28-03-2018 IPR006665 OmpA-like domain SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 PRINTS PR01021 OMPA domain signature 214 230 5.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 PRINTS PR01021 OMPA domain signature 168 190 5.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 PRINTS PR01021 OMPA domain signature 199 214 5.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 Pfam PF04355 SmpA / OmlA family 57 126 1.8E-15 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 SmaCSM2_RS12695 852a1015865eec6136b318588b1eb1bd 280 ProSitePatterns PS01068 OmpA-like domain. 201 245 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 SmaCSM2_RS21335 74ec9749b8275a928146adea05a11f20 243 Pfam PF05076 Suppressor of fused protein (SUFU) 59 232 2.2E-43 T 28-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 SmaCSM2_RS05745 1e23e30d071f87e37deea9de6bbb6f1c 654 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 3 293 7.9E-48 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 SmaCSM2_RS05745 1e23e30d071f87e37deea9de6bbb6f1c 654 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 313 608 2.6E-39 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 SmaCSM2_RS05745 1e23e30d071f87e37deea9de6bbb6f1c 654 Pfam PF03169 OPT oligopeptide transporter protein 9 611 7.3E-124 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 SmaCSM2_RS05745 1e23e30d071f87e37deea9de6bbb6f1c 654 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 10 612 8.8E-175 T 28-03-2018 IPR004814 Oligopeptide transporter OPT SmaCSM2_RS10785 c6337b9da3c60c18a0f25ad338158832 313 Pfam PF07179 SseB protein N-terminal domain 20 125 4.6E-12 T 28-03-2018 IPR009839 SseB protein N-terminal domain SmaCSM2_RS10965 622f01f9bd184865b6222fb145f5a918 997 Pfam PF01526 Tn3 transposase DDE domain 589 975 4.8E-150 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 SmaCSM2_RS10965 622f01f9bd184865b6222fb145f5a918 997 Pfam PF13700 Domain of unknown function (DUF4158) 6 164 1.1E-26 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 SmaCSM2_RS11570 f922fa2c018214d9ec7f9e6f8f50716f 96 Pfam PF11747 Killing trait 11 77 8.0E-29 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS05485 5255ffc9a0d16367441825d8d4b38197 193 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 42 175 7.9E-29 T 28-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 SmaCSM2_RS20175 cc5d6b08251c5e44aa3dfce290e70ee0 177 Gene3D G3DSA:3.40.50.2300 1 142 3.9E-36 T 28-03-2018 SmaCSM2_RS20175 cc5d6b08251c5e44aa3dfce290e70ee0 177 SMART SM00226 4 142 1.7E-36 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS20175 cc5d6b08251c5e44aa3dfce290e70ee0 177 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 135 4.7E-19 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS20175 cc5d6b08251c5e44aa3dfce290e70ee0 177 SUPERFAMILY SSF52788 4 141 2.35E-39 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SmaCSM2_RS16535 65d34fe1449fd20c75a6ed9108b73aa1 523 Gene3D G3DSA:1.25.40.10 88 272 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16535 65d34fe1449fd20c75a6ed9108b73aa1 523 Gene3D G3DSA:1.25.40.10 380 515 0.0071 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16535 65d34fe1449fd20c75a6ed9108b73aa1 523 Gene3D G3DSA:1.25.40.10 273 379 0.48 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS10225 3b70e76d3c527ebf7fd80c0b7124e842 138 SUPERFAMILY SSF101116 11 130 6.54E-35 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 SmaCSM2_RS10225 3b70e76d3c527ebf7fd80c0b7124e842 138 PIRSF PIRSF039090 3 137 4.7E-47 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 SmaCSM2_RS10225 3b70e76d3c527ebf7fd80c0b7124e842 138 Gene3D G3DSA:1.20.120.340 4 130 1.7E-40 T 28-03-2018 SmaCSM2_RS10225 3b70e76d3c527ebf7fd80c0b7124e842 138 Pfam PF02561 Flagellar protein FliS 10 126 4.0E-35 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 SmaCSM2_RS10225 3b70e76d3c527ebf7fd80c0b7124e842 138 TIGRFAM TIGR00208 fliS: flagellar protein FliS 12 126 2.3E-25 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 SmaCSM2_RS03165 4f9e5ea3f8c51b2f90718550bdc55ff3 123 Pfam PF05656 Protein of unknown function (DUF805) 11 119 1.4E-34 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 SmaCSM2_RS19765 34bd8fe841473d77b409a1d996cbeb9a 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 6.9E-18 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 SmaCSM2_RS19765 34bd8fe841473d77b409a1d996cbeb9a 94 PIRSF PIRSF028784 4 94 9.1E-26 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 SmaCSM2_RS09800 44a1ec59d4cc4f93f6935e987d2cf95e 153 Pfam PF14137 Domain of unknown function (DUF4304) 8 86 3.1E-13 T 28-03-2018 IPR025412 Protein of unknown function DUF4304 SmaCSM2_RS11170 798737d474658d15dba47a3dbfad18de 353 Pfam PF13478 XdhC Rossmann domain 209 344 1.2E-25 T 28-03-2018 IPR027051 XdhC Rossmann domain SmaCSM2_RS11170 798737d474658d15dba47a3dbfad18de 353 Pfam PF02625 XdhC and CoxI family 50 108 8.9E-13 T 28-03-2018 IPR003777 XdhC- CoxI SmaCSM2_RS19040 40e22c880e5d5fda4db56bd70e96eb89 569 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 223 2.5E-14 T 28-03-2018 SmaCSM2_RS05490 b11559891d9d3b591378e22f720aff42 252 Gene3D G3DSA:2.60.120.560 55 252 6.3E-40 T 28-03-2018 SmaCSM2_RS05490 b11559891d9d3b591378e22f720aff42 252 Pfam PF06439 Domain of Unknown Function (DUF1080) 58 250 6.0E-39 T 28-03-2018 IPR010496 Domain of unknown function DUF1080 SmaCSM2_RS01125 c53986e0bf86587ef6707a9004c183dd 366 Gene3D G3DSA:3.20.20.70 1 363 3.1E-114 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS01125 c53986e0bf86587ef6707a9004c183dd 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 339 2.0E-63 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SmaCSM2_RS01125 c53986e0bf86587ef6707a9004c183dd 366 SUPERFAMILY SSF51395 2 357 2.63E-111 T 28-03-2018 SmaCSM2_RS12970 fe87e653dfdd197a6ed559ba4d05c4d8 296 Pfam PF04116 Fatty acid hydroxylase superfamily 109 243 1.4E-21 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 SmaCSM2_RS18545 af519f7b3fb3950709aca88f5a2dcc1a 298 SUPERFAMILY SSF103481 46 144 8.24E-16 T 28-03-2018 SmaCSM2_RS18545 af519f7b3fb3950709aca88f5a2dcc1a 298 Pfam PF00892 EamA-like transporter family 10 141 2.9E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS18545 af519f7b3fb3950709aca88f5a2dcc1a 298 Pfam PF00892 EamA-like transporter family 154 279 1.5E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SmaCSM2_RS18545 af519f7b3fb3950709aca88f5a2dcc1a 298 SUPERFAMILY SSF103481 185 285 2.09E-10 T 28-03-2018 SmaCSM2_RS16520 d6c2dac83cdb25352054799be11a9adb 178 Gene3D G3DSA:1.25.40.10 62 167 4.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS16520 d6c2dac83cdb25352054799be11a9adb 178 SUPERFAMILY SSF48452 68 167 1.29E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS09850 810196d24810c54f1dff6a04d888eb77 349 Pfam PF06674 Protein of unknown function (DUF1176) 28 345 1.2E-91 T 28-03-2018 IPR009560 Protein of unknown function DUF1176 SmaCSM2_RS13760 8bd26f7c6a6f3e33d95737fccdb21b87 376 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 43 374 5.5E-100 T 28-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SmaCSM2_RS13760 8bd26f7c6a6f3e33d95737fccdb21b87 376 Gene3D G3DSA:3.75.10.10 31 376 1.1E-112 T 28-03-2018 SmaCSM2_RS13760 8bd26f7c6a6f3e33d95737fccdb21b87 376 SUPERFAMILY SSF55909 37 375 1.09E-112 T 28-03-2018 SmaCSM2_RS00530 6337a41d73b75451e967d59e297db8b9 527 SUPERFAMILY SSF111283 23 518 6.15E-92 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS00530 6337a41d73b75451e967d59e297db8b9 527 Gene3D G3DSA:3.30.2290.10 18 266 3.3E-63 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SmaCSM2_RS00530 6337a41d73b75451e967d59e297db8b9 527 Pfam PF01523 Putative modulator of DNA gyrase 41 367 1.0E-56 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SmaCSM2_RS00735 3761aa9cc32d0031224a7a8c9b77f9cd 221 Pfam PF08816 Inhibitor of vertebrate lysozyme (Ivy) 134 183 1.8E-6 T 28-03-2018 SmaCSM2_RS00735 3761aa9cc32d0031224a7a8c9b77f9cd 221 SUPERFAMILY SSF89872 124 199 1.07E-11 T 28-03-2018 IPR014453 Inhibitor of vertebrate lysozyme GO:0042597|GO:0043086 SmaCSM2_RS00735 3761aa9cc32d0031224a7a8c9b77f9cd 221 Gene3D G3DSA:3.40.1420.10 94 206 2.6E-25 T 28-03-2018 SmaCSM2_RS20315 87e309bd581876511a60fc518a6109a4 156 Pfam PF03031 NLI interacting factor-like phosphatase 5 132 2.7E-8 T 28-03-2018 IPR004274 FCP1 homology domain SmaCSM2_RS20315 87e309bd581876511a60fc518a6109a4 156 Gene3D G3DSA:3.40.50.1000 1 111 5.6E-5 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS20315 87e309bd581876511a60fc518a6109a4 156 SUPERFAMILY SSF56784 3 131 4.65E-10 T 28-03-2018 IPR023214 HAD-like domain SmaCSM2_RS14750 9e5545ad549de743a8b35221007f83fd 309 Pfam PF07920 Protein of unknown function (DUF1684) 164 300 5.1E-42 T 28-03-2018 IPR012467 Protein of unknown function DUF1684 SmaCSM2_RS11390 0fcc6c79eb3d937b1b380473952c7ef1 325 Pfam PF08908 Domain of unknown function (DUF1852) 4 324 5.7E-183 T 28-03-2018 IPR015004 Protein of unknown function DUF1852 SmaCSM2_RS11390 0fcc6c79eb3d937b1b380473952c7ef1 325 PIRSF PIRSF034367 1 325 5.0E-186 T 28-03-2018 IPR015004 Protein of unknown function DUF1852 SmaCSM2_RS19280 d119e869e71854ec8187e8bd22d44009 188 SMART SM00974 18 110 5.6E-8 T 28-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding SmaCSM2_RS08910 dbc66129040bde50e3f2d6b8ecb2fc83 180 Pfam PF03691 Uncharacterised protein family (UPF0167) 6 178 2.5E-42 T 28-03-2018 IPR005363 Uncharacterised protein family UPF0167 SmaCSM2_RS03060 d3cd39635e911f90c67432c14cccb730 733 Pfam PF03170 Bacterial cellulose synthase subunit 46 181 1.2E-4 T 28-03-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 SmaCSM2_RS15810 c5d0b89addebb0ebb987220f5d92f4bf 166 Pfam PF01863 Protein of unknown function DUF45 95 149 3.1E-12 T 28-03-2018 IPR002725 Protein of unknown function DUF45 SmaCSM2_RS12980 bc400ec7d907c2ef7238cf42ca7c2ce5 216 SUPERFAMILY SSF52833 13 214 1.91E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold SmaCSM2_RS12980 bc400ec7d907c2ef7238cf42ca7c2ce5 216 Pfam PF01323 DSBA-like thioredoxin domain 13 210 1.5E-16 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SmaCSM2_RS12980 bc400ec7d907c2ef7238cf42ca7c2ce5 216 Gene3D G3DSA:3.40.30.10 13 216 4.6E-31 T 28-03-2018 SmaCSM2_RS21645 0fe21daf99b399286c41f6c682e1fe81 220 Gene3D G3DSA:3.10.450.50 82 173 6.0E-16 T 28-03-2018 SmaCSM2_RS21645 0fe21daf99b399286c41f6c682e1fe81 220 Pfam PF05494 MlaC protein 45 207 5.0E-42 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC SmaCSM2_RS21645 0fe21daf99b399286c41f6c682e1fe81 220 Gene3D G3DSA:1.10.10.640 174 216 0.0038 T 28-03-2018 SmaCSM2_RS21645 0fe21daf99b399286c41f6c682e1fe81 220 PIRSF PIRSF004649 9 219 5.6E-53 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC SmaCSM2_RS11105 8f0428866671c1f1e2a9430f48ae1e9f 348 SUPERFAMILY SSF52540 32 200 1.37E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS11105 8f0428866671c1f1e2a9430f48ae1e9f 348 Gene3D G3DSA:3.40.50.300 23 209 7.9E-5 T 28-03-2018 SmaCSM2_RS05940 f0394ce5475f4df80a97772261361c85 221 Pfam PF07947 YhhN family 30 220 3.0E-49 T 28-03-2018 IPR012506 YhhN-like GO:0016021 SmaCSM2_RS05145 5426d90799fdaf0c88a258f16ddb0e35 227 Pfam PF11306 Protein of unknown function (DUF3108) 17 208 2.9E-19 T 28-03-2018 IPR021457 Protein of unknown function DUF3108 SmaCSM2_RS14645 6cc597732b0c0dda5bd849c5bc5cfaee 150 SUPERFAMILY SSF82649 15 145 9.94E-42 T 28-03-2018 SmaCSM2_RS14645 6cc597732b0c0dda5bd849c5bc5cfaee 150 Gene3D G3DSA:3.90.1010.10 7 144 4.6E-45 T 28-03-2018 SmaCSM2_RS14645 6cc597732b0c0dda5bd849c5bc5cfaee 150 Pfam PF02657 Fe-S metabolism associated domain 21 139 4.5E-42 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like SmaCSM2_RS01520 c3a7030919b718e8e715747c5a4f4b67 121 Gene3D G3DSA:1.20.120.20 3 107 5.6E-4 T 28-03-2018 SmaCSM2_RS04170 1d2a710a3d49400f9ecd98681f48ea79 204 Pfam PF00849 RNA pseudouridylate synthase 11 159 1.3E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS04170 1d2a710a3d49400f9ecd98681f48ea79 204 SUPERFAMILY SSF55120 3 204 2.88E-58 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SmaCSM2_RS04170 1d2a710a3d49400f9ecd98681f48ea79 204 Gene3D G3DSA:3.30.2350.10 2 204 6.1E-56 T 28-03-2018 SmaCSM2_RS10515 1799c4bed284ae6fc6a763d8441cc040 251 Pfam PF07277 SapC 26 241 3.3E-62 T 28-03-2018 IPR010836 SapC SmaCSM2_RS15675 c8811047248a9f145b30b4dde5fa3dba 227 Pfam PF04367 Protein of unknown function (DUF502) 81 181 1.8E-26 T 28-03-2018 IPR007462 Protein of unknown function DUF502 SmaCSM2_RS20720 fccc55700566da758ca1305da3b1ce46 273 Pfam PF10127 Predicted nucleotidyltransferase 15 265 1.6E-81 T 28-03-2018 IPR018775 Nucleotidyltransferase, predicted SmaCSM2_RS20720 fccc55700566da758ca1305da3b1ce46 273 Gene3D G3DSA:3.30.460.10 2 135 9.0E-4 T 28-03-2018 SmaCSM2_RS00565 6b996d9073f55def2f396e87994c0069 158 Gene3D G3DSA:3.40.50.1240 1 158 2.5E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS00565 6b996d9073f55def2f396e87994c0069 158 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 92 3.4E-13 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS00565 6b996d9073f55def2f396e87994c0069 158 SUPERFAMILY SSF53254 1 143 8.77E-28 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SmaCSM2_RS00565 6b996d9073f55def2f396e87994c0069 158 SMART SM00855 3 114 7.2E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SmaCSM2_RS07005 e0302dad11671ff8e6331408d34d617c 522 Pfam PF05231 MASE1 20 286 5.0E-15 T 28-03-2018 IPR007895 MASE1 SmaCSM2_RS16835 5643f6f98435e12f66246e95bbecce7e 285 Gene3D G3DSA:2.40.50.110 223 284 8.2E-5 T 28-03-2018 SmaCSM2_RS14745 c048a49518052652d7105a4011cb5801 320 Pfam PF01963 TraB family 46 311 2.2E-74 T 28-03-2018 IPR002816 Pheromone shutdown, TraB SmaCSM2_RS00030 0968e0ab9e77a8039c31176874030e66 268 Gene3D G3DSA:3.30.2010.10 48 145 5.1E-21 T 28-03-2018 SmaCSM2_RS00030 0968e0ab9e77a8039c31176874030e66 268 Pfam PF01435 Peptidase family M48 61 246 9.8E-37 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SmaCSM2_RS21110 7723fb8eb88498e9259dca90e438a735 313 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 120 306 1.8E-6 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SmaCSM2_RS05395 aff8b3e00102b4d012f1fe4cc9bd4a5f 263 Gene3D G3DSA:3.40.50.1820 20 258 6.5E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05395 aff8b3e00102b4d012f1fe4cc9bd4a5f 263 SUPERFAMILY SSF53474 23 258 4.95E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS05395 aff8b3e00102b4d012f1fe4cc9bd4a5f 263 Pfam PF01738 Dienelactone hydrolase family 40 258 3.2E-38 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SmaCSM2_RS03345 2d72ee7c0f9edbcce511ae2a6fe6a165 185 Pfam PF11539 Protein of unknown function (DUF3228) 3 183 4.5E-65 T 28-03-2018 IPR021610 Protein of unknown function DUF3228 SmaCSM2_RS05810 b80ea257241beac5496e6f03df9d0db0 197 Pfam PF10882 Bacterial PH domain 85 188 2.7E-6 T 28-03-2018 IPR027783 Bacterial Pleckstrin homology domain-related SmaCSM2_RS01950 50a2ea358973e1f895aba1d2f59f5313 237 Gene3D G3DSA:3.30.1380.10 34 237 1.4E-62 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SmaCSM2_RS01950 50a2ea358973e1f895aba1d2f59f5313 237 SUPERFAMILY SSF55166 36 236 5.49E-59 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SmaCSM2_RS01950 50a2ea358973e1f895aba1d2f59f5313 237 Pfam PF01427 D-ala-D-ala dipeptidase 35 226 7.0E-38 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SmaCSM2_RS01950 50a2ea358973e1f895aba1d2f59f5313 237 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 37 235 31.022 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SmaCSM2_RS01950 50a2ea358973e1f895aba1d2f59f5313 237 PIRSF PIRSF026671 5 237 1.6E-68 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SmaCSM2_RS11065 e05f944a58781c1e878f9e20d9f5da3f 309 Pfam PF13182 Protein of unknown function (DUF4007) 18 296 2.9E-63 T 28-03-2018 IPR025248 Domain of unknown function DUF4007 SmaCSM2_RS07545 c9195768d1cfa7cc606a7407f542fdd7 464 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 48 457 6.4E-178 T 28-03-2018 IPR021204 Integrating conjugative element protein, PFL4711 SmaCSM2_RS00905 be68bd9940a6c53ba1afbc21035411f7 211 Pfam PF02036 SCP-2 sterol transfer family 21 122 7.7E-16 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SmaCSM2_RS12710 fb5bb3049165b6b75fddc232c5765911 62 Pfam PF04964 Flp/Fap pilin component 8 51 2.4E-11 T 28-03-2018 IPR007047 Flp/Fap pilin component SmaCSM2_RS14195 1a22238bdc0e74033b05a451773441c5 281 Pfam PF05433 Glycine zipper 2TM domain 127 167 4.2E-11 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 SmaCSM2_RS19600 9e64c7c21e685b8c9d850ed9cba2beeb 154 Pfam PF04519 Polymer-forming cytoskeletal 18 118 4.8E-26 T 28-03-2018 IPR007607 Protein of unknown function DUF583 SmaCSM2_RS00790 800c03b02a1a7fd5b04636dbb7198314 190 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 3 183 2.2E-22 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SmaCSM2_RS00790 800c03b02a1a7fd5b04636dbb7198314 190 Pfam PF04973 Nicotinamide mononucleotide transporter 2 178 1.3E-47 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SmaCSM2_RS08285 b28572ac0683724deacf02095e6c90fc 222 Pfam PF06912 Protein of unknown function (DUF1275) 13 207 6.1E-37 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 SmaCSM2_RS02860 d5ac3b87d0b4f0022321f8b5b46d200b 124 Pfam PF13511 Domain of unknown function (DUF4124) 10 63 9.7E-16 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 SmaCSM2_RS09470 684994ba6fb4725f4d0efdff1bc87ebe 145 Pfam PF04143 Sulphur transport 4 132 1.2E-6 T 28-03-2018 IPR007272 Sulphur transport domain SmaCSM2_RS18775 c3afdb2bef32b043600c4eef4ec9bfa8 200 Gene3D G3DSA:2.50.20.10 35 199 1.2E-5 T 28-03-2018 SmaCSM2_RS11710 e39c4ceedf2b7ae8398f3bad2466fb2f 362 Pfam PF06224 Winged helix DNA-binding domain 29 361 2.5E-53 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SmaCSM2_RS19680 2a361f8dca642bc1dc8aaacdc9b7bd05 253 Pfam PF01925 Sulfite exporter TauE/SafE 11 240 1.0E-32 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SmaCSM2_RS18090 9c5a7673e18b0f72647a46d83d237b2a 234 Pfam PF01988 VIT family 19 227 1.1E-56 T 28-03-2018 IPR008217 Ccc1 family SmaCSM2_RS05340 e616e8b5443b780e05324e77dd3de1a2 198 Pfam PF07273 Protein of unknown function (DUF1439) 39 161 1.5E-7 T 28-03-2018 IPR010835 Protein of unknown function DUF1439 SmaCSM2_RS05800 f07420ae231a1301dbc5f304e9e71fa8 123 Pfam PF04241 Protein of unknown function (DUF423) 28 106 6.5E-10 T 28-03-2018 IPR006696 Protein of unknown function DUF423 SmaCSM2_RS17840 cbf4cf0b7744fe2c486cd64f145f9103 443 Pfam PF04932 O-Antigen ligase 219 370 2.3E-19 T 28-03-2018 IPR007016 O-antigen ligase-related SmaCSM2_RS14230 0862c6a77a88096978c60c8c5ef871ab 161 Pfam PF04306 Protein of unknown function (DUF456) 23 158 5.1E-38 T 28-03-2018 IPR007403 Protein of unknown function DUF456 SmaCSM2_RS00805 3d86244f5f09b54d4f67887146ba2e98 135 Pfam PF05433 Glycine zipper 2TM domain 38 73 1.1E-8 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 SmaCSM2_RS21590 2032f7e5b18d44ab18a88b9584d09844 69 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 1.4E-22 T 28-03-2018 IPR012451 Protein of unknown function DUF1656 SmaCSM2_RS13905 2d4bcd10cba0433f843debbbaf42538c 180 Pfam PF03691 Uncharacterised protein family (UPF0167) 4 179 2.4E-56 T 28-03-2018 IPR005363 Uncharacterised protein family UPF0167 SmaCSM2_RS02755 93dd8e1e36d3b722e859d80e690e4f60 326 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 22 309 6.2E-32 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SmaCSM2_RS18425 fed4101470005d125ddc5ffaec392a86 140 Pfam PF04120 Low affinity iron permease 7 125 3.8E-53 T 28-03-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 SmaCSM2_RS05185 e03ce1d58d02e657889b707db6f96fe1 389 Pfam PF01594 AI-2E family transporter 19 348 1.3E-56 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SmaCSM2_RS00610 3d2a5ff7a9939a4a631d7349ccc07573 275 Pfam PF03724 META domain 50 164 2.7E-24 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ SmaCSM2_RS00610 3d2a5ff7a9939a4a631d7349ccc07573 275 Pfam PF14302 Domain of unknown function (DUF4377) 184 270 4.0E-24 T 28-03-2018 IPR025485 Domain of unknown function DUF4377 SmaCSM2_RS01760 0f4e4d09c326b513540ac8c1fc385f10 199 Pfam PF04973 Nicotinamide mononucleotide transporter 10 185 1.2E-48 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SmaCSM2_RS01760 0f4e4d09c326b513540ac8c1fc385f10 199 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 13 189 8.1E-22 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SmaCSM2_RS13240 f24df2e83a002fb298910e4e320d251d 67 Pfam PF04024 PspC domain 6 64 5.9E-22 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SmaCSM2_RS12465 6daa5ac26518d91bad0ae2228628bf1e 122 Pfam PF11445 Protein of unknown function (DUF2894) 29 103 2.5E-25 T 28-03-2018 IPR021549 Protein of unknown function DUF2894 SmaCSM2_RS01025 3abd1ae6803259bcc661bcce0c6be1bb 98 TIGRFAM TIGR04509 mod_pep_NH_fam: putative modified peptide 6 90 1.4E-27 T 28-03-2018 IPR030976 Putative modified peptide SmaCSM2_RS20500 ac19fd3ab5299ca0ed1e2f6c7e8277bb 474 Pfam PF02667 Short chain fatty acid transporter 16 459 3.2E-88 T 28-03-2018 IPR006160 Short chain fatty acid transporter AtoE SmaCSM2_RS09340 3275e9d2225c37e837bc2c9200c8b672 344 Pfam PF04235 Protein of unknown function (DUF418) 204 343 5.2E-10 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SmaCSM2_RS09340 3275e9d2225c37e837bc2c9200c8b672 344 Pfam PF07786 Protein of unknown function (DUF1624) 7 196 2.1E-12 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 SmaCSM2_RS12685 223d1ecd428d72815f466e703916f301 275 Pfam PF13649 Methyltransferase domain 51 143 5.3E-18 T 28-03-2018 SmaCSM2_RS12685 223d1ecd428d72815f466e703916f301 275 Gene3D G3DSA:3.40.50.150 18 227 8.7E-31 T 28-03-2018 SmaCSM2_RS12685 223d1ecd428d72815f466e703916f301 275 SUPERFAMILY SSF53335 29 212 1.79E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SmaCSM2_RS13815 b732809163d6cdc9922f0cb7b4ffe2dc 169 Pfam PF16310 Domian of unknown function (DUF4952) 43 119 2.4E-37 T 28-03-2018 IPR032537 Protein of unknown function DUF4952 SmaCSM2_RS17335 471cbb329e95009c3b5107293adf3a7c 120 Gene3D G3DSA:2.40.50.200 15 118 3.3E-22 T 28-03-2018 SmaCSM2_RS17335 471cbb329e95009c3b5107293adf3a7c 120 Pfam PF04076 Bacterial OB fold (BOF) protein 29 115 5.0E-23 T 28-03-2018 IPR005220 Bacterial OB-fold SmaCSM2_RS17335 471cbb329e95009c3b5107293adf3a7c 120 SUPERFAMILY SSF101756 14 116 8.76E-25 T 28-03-2018 IPR005220 Bacterial OB-fold SmaCSM2_RS17960 1e3578815d0d17d033dc2660c7be0bf5 179 SUPERFAMILY SSF48452 4 175 6.83E-62 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS17960 1e3578815d0d17d033dc2660c7be0bf5 179 Gene3D G3DSA:1.20.58.320 1 78 1.4E-21 T 28-03-2018 SmaCSM2_RS17960 1e3578815d0d17d033dc2660c7be0bf5 179 Pfam PF06041 Bacterial protein of unknown function (DUF924) 7 176 1.3E-53 T 28-03-2018 IPR010323 Protein of unknown function DUF924 SmaCSM2_RS17960 1e3578815d0d17d033dc2660c7be0bf5 179 Gene3D G3DSA:1.25.40.10 79 178 1.4E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SmaCSM2_RS13810 8ab9a8458aa23c0108bbd8d668d0a922 476 Gene3D G3DSA:3.40.710.10 154 475 2.3E-84 T 28-03-2018 SmaCSM2_RS13810 8ab9a8458aa23c0108bbd8d668d0a922 476 SUPERFAMILY SSF56601 157 473 1.71E-83 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SmaCSM2_RS13810 8ab9a8458aa23c0108bbd8d668d0a922 476 Pfam PF00144 Beta-lactamase 160 461 1.7E-68 T 28-03-2018 IPR001466 Beta-lactamase-related SmaCSM2_RS04285 6ba91d88e05e79c94805fde7672437ad 485 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 15 168 4.4E-7 T 28-03-2018 IPR018712 Domain of unknown function DUF2235 SmaCSM2_RS04285 6ba91d88e05e79c94805fde7672437ad 485 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 198 275 2.9E-6 T 28-03-2018 IPR018712 Domain of unknown function DUF2235 SmaCSM2_RS02990 28b99df9e7bbb6e30b796b768c022846 287 SUPERFAMILY SSF158544 95 191 3.14E-22 T 28-03-2018 SmaCSM2_RS02990 28b99df9e7bbb6e30b796b768c022846 287 Gene3D G3DSA:1.10.40.60 82 195 5.5E-20 T 28-03-2018 SmaCSM2_RS02990 28b99df9e7bbb6e30b796b768c022846 287 Pfam PF03934 Type II secretion system (T2SS), protein K 31 266 6.4E-42 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 SmaCSM2_RS02990 28b99df9e7bbb6e30b796b768c022846 287 PIRSF PIRSF002786 1 286 1.4E-41 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 SmaCSM2_RS03210 81a3342da6c5b03f393b73a7ccfb6654 159 Pfam PF10517 Electron transfer DM13 60 153 1.2E-20 T 28-03-2018 IPR019545 DM13 domain SmaCSM2_RS02185 910e6e2226236d72ab657f2ee2c1c32b 94 Pfam PF02583 Metal-sensitive transcriptional repressor 7 87 3.3E-18 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SmaCSM2_RS05855 4e752d30db4bf8d89de65f29ed8dd368 169 Gene3D G3DSA:3.30.70.790 1 82 1.0E-13 T 28-03-2018 SmaCSM2_RS20670 7748f5e863dc8ec76380a6383d0c6bc4 210 Pfam PF02698 DUF218 domain 47 191 4.7E-31 T 28-03-2018 IPR003848 Domain of unknown function DUF218 SmaCSM2_RS20670 7748f5e863dc8ec76380a6383d0c6bc4 210 Gene3D G3DSA:3.40.50.620 37 177 1.8E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SmaCSM2_RS01915 8917c386152be1bb34765ff5737b1f80 253 Pfam PF03734 L,D-transpeptidase catalytic domain 41 223 9.5E-6 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SmaCSM2_RS01915 8917c386152be1bb34765ff5737b1f80 253 Gene3D G3DSA:2.40.440.10 39 225 8.1E-5 T 28-03-2018 SmaCSM2_RS01270 fc544de0c8458a04940d955639b03a6d 201 Pfam PF06805 Bacteriophage lambda tail assembly protein I 7 88 1.2E-8 T 28-03-2018 IPR010654 Bacteriophage lambda tail assembly I SmaCSM2_RS08430 97ff45816ea07221a012a55dfc89e6f8 56 Pfam PF07896 Protein of unknown function (DUF1674) 26 56 1.1E-14 T 28-03-2018 IPR012875 Protein of unknown function DUF1674 SmaCSM2_RS15580 955c2627b11620f59acc391c893af330 245 Pfam PF04402 Protein of unknown function (DUF541) 41 241 3.4E-53 T 28-03-2018 IPR007497 Protein of unknown function DUF541 SmaCSM2_RS10465 d3b936421e812b7a7594feab0159b34c 123 Pfam PF05656 Protein of unknown function (DUF805) 11 120 6.2E-30 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 SmaCSM2_RS05420 da4c236b863e92d767b2f97764c2846e 730 SUPERFAMILY SSF48208 95 454 5.83E-37 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SmaCSM2_RS05420 da4c236b863e92d767b2f97764c2846e 730 Gene3D G3DSA:1.50.10.10 56 443 9.5E-36 T 28-03-2018 SmaCSM2_RS00145 897a9333d5f031c6874ae5415a0dfcf5 243 Pfam PF13795 HupE / UreJ protein 60 211 2.9E-53 T 28-03-2018 IPR032809 Putative HupE/UreJ protein SmaCSM2_RS10820 2ba946f1398fb2bb6377dc9b57916f14 276 Pfam PF10670 Domain of unknown function (DUF4198) 19 248 2.2E-23 T 28-03-2018 IPR019613 Protein of unknown function DUF4198 SmaCSM2_RS10820 2ba946f1398fb2bb6377dc9b57916f14 276 Gene3D G3DSA:2.60.40.10 170 255 2.3E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SmaCSM2_RS03295 5ae57f6800c474a55bb7fa90f93a7fd8 149 Pfam PF05258 Protein of unknown function (DUF721) 26 93 1.5E-9 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 SmaCSM2_RS06545 f47d6ee768bd60ba12849f64f404b83c 329 Pfam PF13796 Putative sensor 142 326 1.8E-45 T 28-03-2018 IPR025828 Putative sensor domain SmaCSM2_RS15265 9019acd3773a468bb36a480fcf67d7bf 1796 Gene3D G3DSA:3.40.50.300 1209 1444 7.6E-11 T 28-03-2018 SmaCSM2_RS15265 9019acd3773a468bb36a480fcf67d7bf 1796 Pfam PF12458 ATPase involved in DNA repair 44 491 2.2E-189 T 28-03-2018 IPR020958 DUF3686 SmaCSM2_RS15265 9019acd3773a468bb36a480fcf67d7bf 1796 Pfam PF07728 AAA domain (dynein-related subfamily) 1298 1424 1.4E-5 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SmaCSM2_RS15265 9019acd3773a468bb36a480fcf67d7bf 1796 SUPERFAMILY SSF52540 1293 1443 1.05E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS15265 9019acd3773a468bb36a480fcf67d7bf 1796 SUPERFAMILY SSF52540 1238 1256 1.05E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SmaCSM2_RS19215 0ed854d3363c9bc847be1f71a1cc7f24 203 Gene3D G3DSA:2.60.120.620 17 193 7.4E-14 T 28-03-2018 SmaCSM2_RS10935 a3d7cd4d466851f2e98f3f2c5c5927b9 425 Gene3D G3DSA:1.20.1600.10 6 415 1.8E-38 T 28-03-2018 SmaCSM2_RS10935 a3d7cd4d466851f2e98f3f2c5c5927b9 425 SUPERFAMILY SSF56954 3 411 5.62E-56 T 28-03-2018 SmaCSM2_RS10935 a3d7cd4d466851f2e98f3f2c5c5927b9 425 Pfam PF02321 Outer membrane efflux protein 29 210 7.6E-16 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS10935 a3d7cd4d466851f2e98f3f2c5c5927b9 425 Pfam PF02321 Outer membrane efflux protein 234 409 8.9E-12 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 SmaCSM2_RS14505 d1419b65eef60f38050be2717c55d4c0 149 Pfam PF03918 Cytochrome C biogenesis protein 10 142 1.1E-47 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family SmaCSM2_RS09170 aea05b74542e12f1a93c47c28484f7c3 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 20 70 1.1E-17 T 28-03-2018 IPR007136 Protein of unknown function DUF347 SmaCSM2_RS09170 aea05b74542e12f1a93c47c28484f7c3 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 139 183 2.5E-12 T 28-03-2018 IPR007136 Protein of unknown function DUF347 SmaCSM2_RS09170 aea05b74542e12f1a93c47c28484f7c3 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 74 124 6.2E-15 T 28-03-2018 IPR007136 Protein of unknown function DUF347 SmaCSM2_RS09170 aea05b74542e12f1a93c47c28484f7c3 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 194 249 6.0E-14 T 28-03-2018 IPR007136 Protein of unknown function DUF347 SmaCSM2_RS21380 0955004ba1322b9ace461dfe076e00b8 475 SUPERFAMILY SSF56935 161 475 4.81E-23 T 28-03-2018 SmaCSM2_RS21380 0955004ba1322b9ace461dfe076e00b8 475 SUPERFAMILY SSF56935 99 127 4.81E-23 T 28-03-2018 SmaCSM2_RS00755 f78a5975aecf2fdaf84188c681e69593 90 SUPERFAMILY SSF58042 29 72 6.75E-6 T 28-03-2018 SmaCSM2_RS00755 f78a5975aecf2fdaf84188c681e69593 90 Gene3D G3DSA:1.20.5.1070 26 84 3.9E-7 T 28-03-2018 SmaCSM2_RS20625 b460eb6d3f2c2a0e8db5c4b0cb6c5609 231 SUPERFAMILY SSF53271 67 230 3.45E-25 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SmaCSM2_RS20625 b460eb6d3f2c2a0e8db5c4b0cb6c5609 231 Gene3D G3DSA:3.40.50.2020 77 231 3.8E-26 T 28-03-2018 SmaCSM2_RS20830 075bcaca17bc154459c10b89867ca7d8 154 Gene3D G3DSA:3.30.110.70 47 109 0.0014 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 SmaCSM2_RS04555 48b9786d37d801a6090f10e8f052fa64 127 Pfam PF02643 Uncharacterized ACR, COG1430 17 102 2.2E-12 T 28-03-2018 IPR003795 Protein of unknown function DUF192 SmaCSM2_RS06725 94182105bb3d470fd1b9ca7af877602f 462 Gene3D G3DSA:1.20.91.10 306 389 1.0E-20 T 28-03-2018 SmaCSM2_RS06725 94182105bb3d470fd1b9ca7af877602f 462 Pfam PF00999 Sodium/hydrogen exchanger family 73 455 1.1E-54 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SmaCSM2_RS02830 082d7e160d70d1cb0ea7e3d79831f5e9 308 Pfam PF02470 MlaD protein 39 115 6.9E-14 T 28-03-2018 IPR003399 Mce/MlaD SmaCSM2_RS02830 082d7e160d70d1cb0ea7e3d79831f5e9 308 Gene3D G3DSA:1.20.1170.10 94 291 8.1E-5 T 28-03-2018 SmaCSM2_RS06855 e7dfec71e5055559b39f7198ab0ca7a3 173 Pfam PF07681 DoxX 22 107 1.8E-18 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS21560 0ee32518d1040cd2520fdddd49ab6d09 259 Pfam PF01925 Sulfite exporter TauE/SafE 13 251 2.5E-40 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SmaCSM2_RS09010 87aa348f87868b1765e8647598c9d0b9 329 Pfam PF00953 Glycosyl transferase family 4 78 213 7.5E-25 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SmaCSM2_RS20325 ad393c66659bb4a96036d41513b36db1 154 Pfam PF04966 Carbohydrate-selective porin, OprB family 31 154 1.5E-22 T 28-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 SmaCSM2_RS05560 0e0b683ce47827b54dcbb9eadc89914a 464 Pfam PF11066 Protein of unknown function (DUF2867) 280 436 4.3E-23 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 SmaCSM2_RS11875 3ce948e1c6964fe502d298ebe166268a 213 Pfam PF11736 Protein of unknown function (DUF3299) 98 208 1.5E-36 T 28-03-2018 IPR021727 Protein of unknown function DUF3299 SmaCSM2_RS08405 e53dc273add1825e0f48f48bcd3aa14e 241 SUPERFAMILY SSF100950 12 225 1.02E-43 T 28-03-2018 SmaCSM2_RS08405 e53dc273add1825e0f48f48bcd3aa14e 241 Gene3D G3DSA:3.40.50.1360 2 238 1.2E-45 T 28-03-2018 SmaCSM2_RS08405 e53dc273add1825e0f48f48bcd3aa14e 241 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 18 227 1.8E-47 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SmaCSM2_RS08405 e53dc273add1825e0f48f48bcd3aa14e 241 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 18 230 1.3E-41 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 SmaCSM2_RS00175 96dcb303181b40405b71e434441362b8 270 SUPERFAMILY SSF102114 57 181 9.81E-9 T 28-03-2018 SmaCSM2_RS00175 96dcb303181b40405b71e434441362b8 270 Gene3D G3DSA:3.20.20.70 21 242 1.9E-17 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SmaCSM2_RS00175 96dcb303181b40405b71e434441362b8 270 Pfam PF04055 Radical SAM superfamily 28 155 2.4E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SmaCSM2_RS05015 e867db3433253dc89ad8c55afec5ba4c 235 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 51 223 2.9E-33 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT SmaCSM2_RS15350 0766bb8275955ee10b4bc8084b1a7c7f 279 Pfam PF11227 Protein of unknown function (DUF3025) 67 265 1.6E-56 T 28-03-2018 IPR021390 Protein of unknown function DUF3025 SmaCSM2_RS01385 1799e5ef10f25943ab040b00dc8bb713 45 Pfam PF08085 Entericidin EcnA/B family 22 42 4.4E-10 T 28-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 SmaCSM2_RS08890 fcba51c11b663cc863a3041fc35691fc 521 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 4 503 42.795 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 SmaCSM2_RS08890 fcba51c11b663cc863a3041fc35691fc 521 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 29 485 1.1E-128 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 SmaCSM2_RS01900 b91cfd02ef89a66f1401ef0b3450b3d0 151 Pfam PF05360 yiaA/B two helix domain 13 66 1.0E-20 T 28-03-2018 IPR008024 YiaAB two helix SmaCSM2_RS01900 b91cfd02ef89a66f1401ef0b3450b3d0 151 Pfam PF05360 yiaA/B two helix domain 77 129 6.7E-21 T 28-03-2018 IPR008024 YiaAB two helix SmaCSM2_RS06860 f8a57db314de46c7dce5107f6e6b0b4b 251 Pfam PF09836 Putative DNA-binding domain 11 96 1.2E-26 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria SmaCSM2_RS13655 fea621c0c59f0cc72e80ecb0b7bce222 91 TIGRFAM TIGR02610 PHA_gran_rgn: putative polyhydroxyalkanoic acid system protein 1 90 6.8E-34 T 28-03-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein SmaCSM2_RS13655 fea621c0c59f0cc72e80ecb0b7bce222 91 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 4 90 2.1E-31 T 28-03-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein SmaCSM2_RS02150 5e874cd361a308c441bf7d9f2915308e 181 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 6 179 34.206 T 28-03-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 SmaCSM2_RS02150 5e874cd361a308c441bf7d9f2915308e 181 SUPERFAMILY SSF56399 9 179 1.27E-59 T 28-03-2018 SmaCSM2_RS02150 5e874cd361a308c441bf7d9f2915308e 181 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 7 172 3.1E-43 T 28-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 SmaCSM2_RS07590 0b054d571adae727d92fb7066468ba82 229 Pfam PF11444 Protein of unknown function (DUF2895) 6 206 2.0E-90 T 28-03-2018 IPR021548 Protein of unknown function DUF2895 SmaCSM2_RS07590 0b054d571adae727d92fb7066468ba82 229 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 207 9.3E-96 T 28-03-2018 IPR021548 Protein of unknown function DUF2895 SmaCSM2_RS09255 402afc7d9126f1a4f48c873cb9f8cb46 120 Pfam PF11287 Protein of unknown function (DUF3088) 8 116 5.4E-36 T 28-03-2018 IPR021439 Protein of unknown function DUF3088 SmaCSM2_RS11585 85a27fe7dabd457fcd41382511581846 90 Pfam PF11747 Killing trait 11 78 5.7E-30 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS18375 d9b7e47a62f916f70341203eacc41b8c 367 Pfam PF04085 rod shape-determining protein MreC 134 274 5.2E-34 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SmaCSM2_RS18375 d9b7e47a62f916f70341203eacc41b8c 367 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 20 276 7.6E-51 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SmaCSM2_RS03395 cab372c98981ee341e9977f0ff3a4e34 266 Gene3D G3DSA:3.60.21.10 11 255 9.3E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS03395 cab372c98981ee341e9977f0ff3a4e34 266 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 14 227 1.1E-8 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SmaCSM2_RS03395 cab372c98981ee341e9977f0ff3a4e34 266 SUPERFAMILY SSF56300 189 254 1.9E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS03395 cab372c98981ee341e9977f0ff3a4e34 266 SUPERFAMILY SSF56300 12 133 1.9E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SmaCSM2_RS03080 66010b733e00c3f21c23468bbe89db02 438 PIRSF PIRSF005353 1 438 3.7E-166 T 28-03-2018 IPR026033 Purine permease PbuG-like SmaCSM2_RS03080 66010b733e00c3f21c23468bbe89db02 438 Pfam PF00860 Permease family 20 398 2.7E-46 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SmaCSM2_RS19325 ef55aaed2a33ed47117507d1fb5bfbde 139 Pfam PF07007 Lysozyme inhibitor LprI 32 132 4.7E-14 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal SmaCSM2_RS19575 b7f3e5e3632ed9b797375a04ddea06e1 92 Pfam PF04505 Interferon-induced transmembrane protein 9 74 2.1E-23 T 28-03-2018 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 SmaCSM2_RS01215 2e2adfb031ad1603f263e85d0d251941 170 Pfam PF05135 Phage gp6-like head-tail connector protein 4 65 2.2E-10 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein SmaCSM2_RS05575 fa1664c50a735c5dee6f14f32cd61e45 155 Pfam PF11188 Protein of unknown function (DUF2975) 47 152 2.6E-14 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 SmaCSM2_RS03195 f4f291ecda70db2986077c0c2a6d664e 573 Pfam PF04348 LppC putative lipoprotein 45 564 2.0E-110 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA SmaCSM2_RS03195 f4f291ecda70db2986077c0c2a6d664e 573 SUPERFAMILY SSF53822 252 569 3.53E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SmaCSM2_RS03195 f4f291ecda70db2986077c0c2a6d664e 573 Gene3D G3DSA:3.40.50.2300 386 555 2.6E-8 T 28-03-2018 SmaCSM2_RS03195 f4f291ecda70db2986077c0c2a6d664e 573 Gene3D G3DSA:3.40.50.2300 251 385 1.5E-17 T 28-03-2018 SmaCSM2_RS12225 6d00fbcddebc23b6f545c66a280c9cbb 104 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 12 100 1.0E-16 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD SmaCSM2_RS06535 d6811a563430e4f452c655443ee97c29 298 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 52 225 1.3E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SmaCSM2_RS06535 d6811a563430e4f452c655443ee97c29 298 Gene3D G3DSA:2.40.100.10 28 259 1.7E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain SmaCSM2_RS06535 d6811a563430e4f452c655443ee97c29 298 SUPERFAMILY SSF50891 50 126 2.34E-27 T 28-03-2018 IPR029000 Cyclophilin-like domain SmaCSM2_RS06535 d6811a563430e4f452c655443ee97c29 298 SUPERFAMILY SSF50891 163 266 2.34E-27 T 28-03-2018 IPR029000 Cyclophilin-like domain SmaCSM2_RS20225 384b9ef7659e12b05728e3042aaf6c4f 90 Pfam PF02583 Metal-sensitive transcriptional repressor 19 86 1.8E-10 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SmaCSM2_RS17555 8b989b69c8be00370a3a93589c134c6b 313 Pfam PF12889 Protein of unknown function (DUF3829) 32 311 9.7E-57 T 28-03-2018 IPR024291 Protein of unknown function DUF3829 SmaCSM2_RS07285 91216fe703d11405cc0f31e737eb1912 255 Pfam PF06629 MltA-interacting protein MipA 36 255 7.8E-39 T 28-03-2018 IPR010583 MltA-interacting MipA SmaCSM2_RS15685 01f3c524a0f9fc2210b1de3a523a94ab 646 Pfam PF05960 Bacterial protein of unknown function (DUF885) 97 630 9.0E-143 T 28-03-2018 IPR010281 Protein of unknown function DUF885 SmaCSM2_RS06420 68d0990cf5f911e0ec5acd1ea7f9df51 181 Pfam PF13211 Protein of unknown function (DUF4019) 68 174 5.8E-27 T 28-03-2018 IPR025091 Protein of unknown function DUF4019 SmaCSM2_RS03460 be520a245f884b7063b58b7531274ff0 117 PIRSF PIRSF021239 6 117 5.7E-51 T 28-03-2018 IPR007437 Putative member of DMT superfamily SmaCSM2_RS03460 be520a245f884b7063b58b7531274ff0 117 Pfam PF04342 Putative member of DMT superfamily (DUF486) 13 115 1.2E-45 T 28-03-2018 IPR007437 Putative member of DMT superfamily SmaCSM2_RS21245 99357e16baf6c9b902619636d6915078 155 Pfam PF05117 Family of unknown function (DUF695) 19 147 1.1E-20 T 28-03-2018 IPR016097 Domain of unknown function DUF695 SmaCSM2_RS12440 cf554f041995b69a5a17d6c5cdc70c71 130 Gene3D G3DSA:1.10.3830.10 18 130 4.4E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SmaCSM2_RS12440 cf554f041995b69a5a17d6c5cdc70c71 130 Pfam PF01219 Prokaryotic diacylglycerol kinase 28 128 6.4E-30 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SmaCSM2_RS12440 cf554f041995b69a5a17d6c5cdc70c71 130 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 81 92 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SmaCSM2_RS00280 a0a02ad76a600a266dfdea476236144e 292 SUPERFAMILY SSF53474 31 226 5.61E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS00280 a0a02ad76a600a266dfdea476236144e 292 Gene3D G3DSA:3.40.50.1820 20 278 3.0E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SmaCSM2_RS10150 b4a75b60658e558d3255b26208d8b85f 171 Pfam PF03748 Flagellar basal body-associated protein FliL 69 171 2.6E-24 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 SmaCSM2_RS14090 ddd1d12426f374fa39281da8d8ea1385 201 Pfam PF11101 Protein of unknown function (DUF2884) 56 137 1.2E-9 T 28-03-2018 IPR021307 Protein of unknown function DUF2884 SmaCSM2_RS19965 edd183b53df436e41892dda0b2e1a732 148 Pfam PF14106 Domain of unknown function (DUF4279) 14 128 2.9E-20 T 28-03-2018 IPR025459 Protein of unknown function DUF4279 SmaCSM2_RS11215 e4000711eb51662ac72c6ffa51825a5d 201 Pfam PF11769 Protein of unknown function (DUF3313) 3 176 2.3E-13 T 28-03-2018 IPR021747 Protein of unknown function DUF3313 SmaCSM2_RS05225 ad0a593954e76df8a8110025dee94483 241 Pfam PF13645 L,D-transpeptidase catalytic domain 46 215 7.4E-61 T 28-03-2018 IPR032676 Putative L,D-transpeptidase catalytic domain SmaCSM2_RS00865 bb69bf10d5962bec220a056514bc295b 105 Pfam PF13698 Domain of unknown function (DUF4156) 21 102 2.6E-9 T 28-03-2018 IPR025294 Protein of unknown function DUF4156 SmaCSM2_RS16815 51ee5f11566d4ea421acd9bee38dd072 273 Pfam PF11219 Protein of unknown function (DUF3014) 112 268 5.8E-51 T 28-03-2018 IPR021382 Protein of unknown function DUF3014 SmaCSM2_RS07460 f078e73faf3c12890298d61dcd183e32 296 Pfam PF00795 Carbon-nitrogen hydrolase 2 213 2.2E-18 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS07460 f078e73faf3c12890298d61dcd183e32 296 Gene3D G3DSA:3.60.110.10 1 279 2.5E-40 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS07460 f078e73faf3c12890298d61dcd183e32 296 SUPERFAMILY SSF56317 1 269 2.22E-43 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SmaCSM2_RS11590 db953cabecea76300be1c78ce27cacb4 78 Pfam PF11747 Killing trait 21 74 1.9E-13 T 28-03-2018 IPR021070 Killing trait, RebB SmaCSM2_RS16870 eff61d8b0e91631b31c091f3fc968758 168 Pfam PF13761 Domain of unknown function (DUF4166) 9 165 5.4E-33 T 28-03-2018 IPR025311 Domain of unknown function DUF4166 SmaCSM2_RS03500 e4934d17a0f8bc82cd9e81e841e50786 249 Pfam PF03741 Integral membrane protein TerC family 16 206 6.4E-49 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SmaCSM2_RS04775 353e79e23cf5fddcac8336d3d2710ad8 169 Pfam PF02620 Uncharacterized ACR, COG1399 61 167 2.6E-14 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD SmaCSM2_RS10690 0a914497f6923002093c1419eeba2992 112 Pfam PF12375 Phage protein 10 50 3.8E-9 T 28-03-2018 IPR021077 Bacteriophage phi-Lf, Orf112 SmaCSM2_RS13310 be4441f3bfd66e8e783860782aeaccba 290 Pfam PF12787 EcsC protein family 36 263 1.2E-36 T 28-03-2018 IPR024787 EcsC protein SmaCSM2_RS20385 c1835f3dd49b9719ffeea72715104abd 436 SUPERFAMILY SSF50952 126 434 1.57E-29 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SmaCSM2_RS20385 c1835f3dd49b9719ffeea72715104abd 436 SUPERFAMILY SSF50952 65 97 1.57E-29 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SmaCSM2_RS20385 c1835f3dd49b9719ffeea72715104abd 436 Pfam PF07995 Glucose / Sorbosone dehydrogenase 184 361 3.7E-14 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SmaCSM2_RS20385 c1835f3dd49b9719ffeea72715104abd 436 Gene3D G3DSA:2.120.10.30 325 436 8.7E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS20385 c1835f3dd49b9719ffeea72715104abd 436 Gene3D G3DSA:2.120.10.30 55 324 6.1E-32 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SmaCSM2_RS14005 d6a49f9ed2259dbb42403ebb059905e2 95 Gene3D G3DSA:1.20.1630.10 6 95 9.8E-4 T 28-03-2018 SmaCSM2_RS02890 55072d0c932a785d6c2bbf6163e1f41d 63 Pfam PF01679 Proteolipid membrane potential modulator 1 47 2.5E-7 T 28-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 Gene3D G3DSA:2.130.10.150 41 138 1.1E-12 T 28-03-2018 SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 Gene3D G3DSA:2.130.10.150 139 288 1.6E-6 T 28-03-2018 SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 SUPERFAMILY SSF82171 44 177 1.88E-17 T 28-03-2018 SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 Pfam PF07676 WD40-like Beta Propeller Repeat 38 73 1.1E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 Pfam PF07676 WD40-like Beta Propeller Repeat 89 124 7.4E-10 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS11520 9968ebae24013d3ed9a2f6337e929a1a 293 Pfam PF07676 WD40-like Beta Propeller Repeat 139 177 7.9E-10 T 28-03-2018 IPR011659 WD40-like Beta Propeller SmaCSM2_RS05605 b998d6b16336e8cb14c5831beaac06fe 261 Pfam PF09836 Putative DNA-binding domain 8 92 7.8E-19 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria SmaCSM2_RS03515 bc275fc11003d85992a490bdd0b449c2 295 Pfam PF04536 TPM domain 33 154 4.7E-37 T 28-03-2018 IPR007621 TPM domain SmaCSM2_RS19470 063fa4ef2998640d9afa1b9e88818b88 296 Gene3D G3DSA:3.30.1150.10 21 114 0.017 T 28-03-2018 SmaCSM2_RS19470 063fa4ef2998640d9afa1b9e88818b88 296 Gene3D G3DSA:3.30.1150.10 121 242 1.4E-15 T 28-03-2018 SmaCSM2_RS19470 063fa4ef2998640d9afa1b9e88818b88 296 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 139 231 5.2E-8 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 SmaCSM2_RS19470 063fa4ef2998640d9afa1b9e88818b88 296 SUPERFAMILY SSF74653 137 226 1.12E-9 T 28-03-2018 SmaCSM2_RS05435 48d88849ffdc8c2bcbfbacf110428658 128 Pfam PF07179 SseB protein N-terminal domain 10 118 1.5E-5 T 28-03-2018 IPR009839 SseB protein N-terminal domain SmaCSM2_RS15270 bd8b8c0906351a72367544e2bd3a7448 672 SUPERFAMILY SSF117892 67 185 2.48E-8 T 28-03-2018 IPR001107 Band 7 domain SmaCSM2_RS21220 1ce3d0f5f9e932968a996ddd100260cb 94 Pfam PF11191 Protein of unknown function (DUF2782) 39 94 2.8E-17 T 28-03-2018 IPR021357 Protein of unknown function DUF2782 SmaCSM2_RS05820 c4d08e0b1effbbd8065943d2e6fbb3ba 59 Gene3D G3DSA:1.10.1220.10 4 44 2.1E-14 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SmaCSM2_RS05820 c4d08e0b1effbbd8065943d2e6fbb3ba 59 SUPERFAMILY SSF47598 1 51 4.78E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SmaCSM2_RS17510 71d4907e16d36d7c94e4523f8323184c 147 Pfam PF02643 Uncharacterized ACR, COG1430 35 141 7.6E-32 T 28-03-2018 IPR003795 Protein of unknown function DUF192 SmaCSM2_RS13385 3abe79d55f06117f7e11e1c04bec4c35 180 Pfam PF13827 Domain of unknown function (DUF4189) 73 172 1.3E-18 T 28-03-2018 IPR025240 Domain of unknown function DUF4189 SmaCSM2_RS15525 458fcfd76fd38c59f80c368fbcba75be 121 Pfam PF13276 HTH-like domain 4 53 1.8E-8 T 28-03-2018 IPR025948 HTH-like domain SmaCSM2_RS01680 73a182830693a80055f4ec24bcec1e57 76 SUPERFAMILY SSF47598 2 44 8.89E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SmaCSM2_RS03465 6c0f27605683ca2d8798217cdc4d2362 838 Pfam PF02687 FtsX-like permease family 285 373 1.8E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS03465 6c0f27605683ca2d8798217cdc4d2362 838 Pfam PF02687 FtsX-like permease family 744 831 5.8E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SmaCSM2_RS17650 34d3caab8a4772a9c27ae997f3fc8385 155 Pfam PF04304 Protein of unknown function (DUF454) 2 116 2.2E-34 T 28-03-2018 IPR007401 Protein of unknown function DUF454 SmaCSM2_RS17320 3da9ac60f218ff29b03eb51561616aa7 377 Pfam PF07434 CblD like pilus biogenesis initiator 30 370 7.6E-46 T 28-03-2018 IPR010888 CblD-like pilus biogenesis initiator SmaCSM2_RS02605 44ce29472442db172b91554043180886 207 SUPERFAMILY SSF56935 18 147 3.4E-6 T 28-03-2018 SmaCSM2_RS02605 44ce29472442db172b91554043180886 207 Gene3D G3DSA:2.40.160.20 24 207 1.5E-6 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 SmaCSM2_RS19605 ccbc400ae0ed340625f1f2505af8c59c 247 Gene3D G3DSA:1.20.1170.10 34 157 1.9E-4 T 28-03-2018 SmaCSM2_RS07695 d554c04a6981e956acc7f0be0e957b37 229 Pfam PF11679 Protein of unknown function (DUF3275) 14 222 2.5E-91 T 28-03-2018 IPR021693 Protein of unknown function DUF3275 SmaCSM2_RS08575 1fc6af0b6757fa6053961cf3a0206f30 194 Gene3D G3DSA:3.40.1580.10 15 179 2.7E-5 T 28-03-2018 SmaCSM2_RS17170 e1c7181ee2a7a3632d2c5ea30c341ebf 892 PIRSF PIRSF035905 492 649 170.0 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein SmaCSM2_RS17170 e1c7181ee2a7a3632d2c5ea30c341ebf 892 PIRSF PIRSF035905 698 891 1.4E-10 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein SmaCSM2_RS17170 e1c7181ee2a7a3632d2c5ea30c341ebf 892 PIRSF PIRSF035905 536 698 4000.0 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein SmaCSM2_RS17170 e1c7181ee2a7a3632d2c5ea30c341ebf 892 PIRSF PIRSF035905 1 500 1.1E-54 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein SmaCSM2_RS17170 e1c7181ee2a7a3632d2c5ea30c341ebf 892 Pfam PF10101 Predicted membrane protein (DUF2339) 138 881 2.1E-150 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane SmaCSM2_RS01820 ac1847cee7e7f05035d2ec8ca2ec1a66 387 Pfam PF02628 Cytochrome oxidase assembly protein 140 377 1.7E-44 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SmaCSM2_RS01820 ac1847cee7e7f05035d2ec8ca2ec1a66 387 Pfam PF02628 Cytochrome oxidase assembly protein 15 138 2.7E-21 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SmaCSM2_RS18470 6f4a5249c4372197cc572f66833d9a77 66 Pfam PF11278 Protein of unknown function (DUF3079) 1 49 8.0E-31 T 28-03-2018 IPR021430 Protein of unknown function DUF3079 SmaCSM2_RS02190 554fc199e63b9fc0e07b4c380c0d4558 123 Pfam PF03203 MerC mercury resistance protein 10 119 3.4E-22 T 28-03-2018 IPR004891 MerC mercury resistance protein SmaCSM2_RS19610 30ca35d2712a0dc76a867fe7eedfae96 205 Pfam PF13548 Domain of unknown function (DUF4126) 9 175 2.1E-46 T 28-03-2018 IPR025196 Domain of unknown function DUF4126 SmaCSM2_RS17455 fcc486ab45e0d5dc902171f1b3f0911d 759 Pfam PF07793 Protein of unknown function (DUF1631) 20 746 2.6E-184 T 28-03-2018 IPR012434 Protein of unknown function DUF1631 SmaCSM2_RS04765 771a81a6848c9b70b0ced04600cb2e8c 611 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 51 211 3.8E-16 T 28-03-2018 SmaCSM2_RS18185 0238863db7ac9fb4d5f119233af68fca 144 Pfam PF07179 SseB protein N-terminal domain 19 129 9.9E-15 T 28-03-2018 IPR009839 SseB protein N-terminal domain SmaCSM2_RS05530 c982d168ea7aedd9f3d354ff10d886e6 341 Pfam PF01594 AI-2E family transporter 16 333 2.6E-10 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SmaCSM2_RS07530 8977c00661124b8f67c4019536184968 121 Pfam PF12553 Protein of unknown function (DUF3742) 1 105 2.9E-38 T 28-03-2018 IPR022213 Protein of unknown function DUF3742 SmaCSM2_RS11730 54e72cfa149302cff753e6b27f965481 221 Pfam PF05857 TraX protein 20 217 1.5E-42 T 28-03-2018 IPR008875 TraX SmaCSM2_RS09000 a808273d3403bfd9c6992758f36f26ed 94 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 77 5.8E-7 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 SmaCSM2_RS10170 b88e1909bfecad301e328bc91e681cbc 213 Pfam PF02108 Flagellar assembly protein FliH 80 199 3.1E-20 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE SmaCSM2_RS00945 a7854b07797dcde9c59d12676365b3f8 175 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 101 159 4.5E-19 T 28-03-2018 IPR018637 Domain of unknown function DUF2059 SmaCSM2_RS05160 757e01af031e7160171f9b3922b753ed 220 Pfam PF09997 Predicted membrane protein (DUF2238) 53 203 6.0E-46 T 28-03-2018 IPR014509 Uncharacterised conserved protein UCP020606 SmaCSM2_RS05620 9327b1315a2aa9a660ec61b330fec9b2 214 Pfam PF07681 DoxX 22 107 1.4E-16 T 28-03-2018 IPR032808 DoxX family SmaCSM2_RS12720 53c0401d276daeedfcd203b2fd8f77d9 158 Pfam PF07811 TadE-like protein 11 54 4.7E-8 T 28-03-2018 IPR012495 TadE-like SmaCSM2_RS11900 d6199d9b777ece6876874d3e93a3f1f6 158 Pfam PF03203 MerC mercury resistance protein 26 152 1.8E-15 T 28-03-2018 IPR004891 MerC mercury resistance protein SmaCSM2_RS11745 a57b87617300d6d90cf3c45d087218e1 99 SUPERFAMILY SSF158791 10 71 6.02E-5 T 28-03-2018 SmaCSM2_RS04935 f5ded62e6ef52881c90f4434b0359a29 324 Pfam PF13387 Domain of unknown function (DUF4105) 111 262 9.7E-46 T 28-03-2018 IPR025178 Domain of unknown function DUF4105 SmaCSM2_RS07640 af931487fd39dd1d7d7e330ce2abdaf5 213 Gene3D G3DSA:1.20.1170.10 27 201 2.2E-6 T 28-03-2018 SmaCSM2_RS16585 49d41289841546dd0fe1878a7370399b 102 Pfam PF13453 Transcription factor zinc-finger 3 43 3.7E-21 T 28-03-2018 IPR027392 Transcription factor zinc-finger SmaCSM2_RS03400 dffacc6322e07fb1d3024531d0fa79f6 352 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 1.2E-27 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase SmaCSM2_RS04755 623ecdaab74db1bbbb0e71866dec8f37 314 Pfam PF01882 Protein of unknown function DUF58 207 283 2.2E-15 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SmaCSM2_RS00760 61d1f3312e19409596acacb7079f3bad 316 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 133 279 2.9E-7 T 28-03-2018 IPR018728 Domain of unknown function DUF2268 SmaCSM2_RS03735 cc53519e6e0ae4020d9c0ea7623aa31b 106 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 8 90 4.3E-28 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 SmaCSM2_RS02060 43b95d2f2a26f060cc917b82f9f23144 259 Pfam PF14487 Domain of unknown function (DUF4433) 57 247 2.4E-12 T 28-03-2018 IPR029494 Domain of unknown function DUF4433 SmaCSM2_RS07480 afdd54ef24928672976e25240d900333 444 Pfam PF11902 Protein of unknown function (DUF3422) 26 434 2.9E-147 T 28-03-2018 IPR021830 Protein of unknown function DUF3422 SmaCSM2_RS17165 273c48fc1043bb96e9260c1260332d0b 458 Pfam PF13163 Protein of unknown function (DUF3999) 29 449 2.9E-117 T 28-03-2018 IPR025060 Protein of unknown function DUF3999 SmaCSM2_RS09860 7a346ac9f509471dc45ba4ac4b8c6338 399 Pfam PF01757 Acyltransferase family 4 367 3.5E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SmaCSM2_RS12455 fa9cbbb7a7ba0f3fd48121967bb7a68e 754 Pfam PF05650 Domain of unknown function (DUF802) 321 373 7.7E-10 T 28-03-2018 IPR008520 Domain of unknown function DUF802 SmaCSM2_RS12455 fa9cbbb7a7ba0f3fd48121967bb7a68e 754 Gene3D G3DSA:1.20.120.290 518 621 0.015 T 28-03-2018 SmaCSM2_RS12455 fa9cbbb7a7ba0f3fd48121967bb7a68e 754 Gene3D G3DSA:1.20.120.290 460 517 0.014 T 28-03-2018 SmaCSM2_RS12455 fa9cbbb7a7ba0f3fd48121967bb7a68e 754 Gene3D G3DSA:1.20.120.290 381 459 2.2E-6 T 28-03-2018 SmaCSM2_RS12455 fa9cbbb7a7ba0f3fd48121967bb7a68e 754 Gene3D G3DSA:1.20.120.290 311 380 4.1E-7 T 28-03-2018 SmaCSM2_RS02375 f8f0e22406e8e9def376d2a3bd6be42d 82 Pfam PF11730 Protein of unknown function (DUF3297) 6 76 1.2E-38 T 28-03-2018 IPR021724 Protein of unknown function DUF3297 SmaCSM2_RS12765 3799bfe6563e03c5cf7e2bef7b2af027 716 Pfam PF09977 Putative Tad-like Flp pilus-assembly 56 145 1.5E-10 T 28-03-2018 IPR018705 Domain of unknown function DUF2134, membrane SmaCSM2_RS13805 e285a6649da25478d50bd2dbbaf165c3 130 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 4.5E-39 T 28-03-2018 IPR021398 Protein of unknown function DUF3037 SmaCSM2_RS21360 bec4aba89dedca6fe31ab62db6068bcd 83 Pfam PF04226 Transglycosylase associated protein 33 79 4.7E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SmaCSM2_RS04365 7891b80cf983b18914bcf48921ceca3b 250 Pfam PF01925 Sulfite exporter TauE/SafE 9 237 2.8E-27 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SmaCSM2_RS20110 b4ca6f25b66c10b8ac3a6a242df325ea 423 Pfam PF10011 Predicted membrane protein (DUF2254) 14 369 1.4E-85 T 28-03-2018 IPR018723 Protein of unknown function DUF2254, membrane SmaCSM2_RS07020 2e8a6cb14b3e8ada46ee23b08ff78bc7 534 Pfam PF05231 MASE1 20 286 4.1E-15 T 28-03-2018 IPR007895 MASE1 SmaCSM2_RS00025 b1ed83cf327e9c121862bcd6f6200e2b 282 Pfam PF02517 CAAX protease self-immunity 172 271 3.0E-20 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SmaCSM2_RS00295 d263a4fc9ffef08a4d376bd8e735e9a0 400 Pfam PF00487 Fatty acid desaturase 18 229 4.2E-12 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629