locus-tag	class	description
CEQ03_RS00010	COG2902	Dehydrogenase
CEQ03_RS00035	COG2925	Exonuclease
CEQ03_RS00040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ03_RS00045	COG3844	kynureninase activity
CEQ03_RS00055	COG0288	reversible hydration of carbon dioxide
CEQ03_RS00075	COG0017	Asparaginyl-tRNA synthetase
CEQ03_RS00080	COG0316	Belongs to the HesB IscA family
CEQ03_RS00090	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ03_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEQ03_RS00100	COG0359	binds to the 23S rRNA
CEQ03_RS00115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ03_RS00120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEQ03_RS00130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEQ03_RS00140	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CEQ03_RS00150	COG4993	Dehydrogenase
CEQ03_RS00220	COG0583	DNA-binding transcription factor activity
CEQ03_RS00225	COG2957	Belongs to the agmatine deiminase family
CEQ03_RS00270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CEQ03_RS00285	COG1228	amidohydrolase
CEQ03_RS00330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEQ03_RS00335	COG1605	Chorismate mutase
CEQ03_RS00335	COG0077	Prephenate dehydratase
CEQ03_RS00340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEQ03_RS00355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEQ03_RS00365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEQ03_RS00370	COG0583	DNA-binding transcription factor activity
CEQ03_RS00400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ03_RS00420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ03_RS00435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CEQ03_RS00450	COG0210	DNA helicase
CEQ03_RS00465	COG0604	alcohol dehydrogenase
CEQ03_RS00470	COG1733	regulation of RNA biosynthetic process
CEQ03_RS00490	COG4774	siderophore transport
CEQ03_RS00505	COG4191	Histidine kinase
CEQ03_RS00505	COG0784	Response regulator, receiver
CEQ03_RS00540	COG0789	Transcriptional regulator
CEQ03_RS00545	COG2814	Major facilitator Superfamily
CEQ03_RS00560	COG3505	Type IV secretory pathway VirD4
CEQ03_RS00570	COG3736	Type IV secretory pathway, component VirB8
CEQ03_RS00580	COG2948	multi-organism process
CEQ03_RS00600	COG3702	type iv secretory pathway
CEQ03_RS00675	COG0456	acetyltransferase
CEQ03_RS00680	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ03_RS00685	COG1733	regulation of RNA biosynthetic process
CEQ03_RS00710	COG0668	transmembrane transport
CEQ03_RS00720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEQ03_RS00740	COG0534	Mate efflux family protein
CEQ03_RS00745	COG1073	alpha beta
CEQ03_RS00745	COG2226	methyltransferase
CEQ03_RS00760	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEQ03_RS00770	COG1983	PspC domain protein
CEQ03_RS00790	COG2183	response to ionizing radiation
CEQ03_RS00795	COG5001	Diguanylate cyclase
CEQ03_RS00795	COG3447	MASE1 domain protein
CEQ03_RS00795	COG5002	protein histidine kinase activity
CEQ03_RS00885	COG0789	Transcriptional regulator
CEQ03_RS00895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ03_RS00910	COG0531	amino acid
CEQ03_RS00950	COG1595	DNA-templated transcription, initiation
CEQ03_RS00965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ03_RS00965	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ03_RS00970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ03_RS00985	COG0587	DNA-directed DNA polymerase activity
CEQ03_RS01045	COG2814	Major facilitator Superfamily
CEQ03_RS01070	COG1285	pathogenesis
CEQ03_RS01080	COG2186	Transcriptional regulator
CEQ03_RS01085	COG1304	FMN binding
CEQ03_RS01090	COG0277	FAD linked oxidase domain protein
CEQ03_RS01130	COG3161	chorismate lyase activity
CEQ03_RS01145	COG0583	DNA-binding transcription factor activity
CEQ03_RS01155	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEQ03_RS01165	COG2814	Major facilitator Superfamily
CEQ03_RS01170	COG2197	response regulator
CEQ03_RS01175	COG3850	Histidine kinase
CEQ03_RS01190	COG1335	isochorismatase
CEQ03_RS01200	COG1228	amidohydrolase
CEQ03_RS01265	COG4964	Belongs to the GSP D family
CEQ03_RS01310	COG2226	methyltransferase
CEQ03_RS01330	COG4772	TonB-dependent receptor
CEQ03_RS01375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ03_RS01380	COG4206	TonB-dependent receptor
CEQ03_RS01390	COG0604	alcohol dehydrogenase
CEQ03_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS01390	COG3321	synthase
CEQ03_RS01395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ03_RS01400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ03_RS01415	COG1914	H( )-stimulated, divalent metal cation uptake system
CEQ03_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ03_RS01495	COG2409	Drug exporters of the RND superfamily
CEQ03_RS01505	COG1169	isochorismate synthase
CEQ03_RS01510	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEQ03_RS01515	COG3433	isochorismatase activity
CEQ03_RS01515	COG1535	isochorismatase
CEQ03_RS01520	COG3433	isochorismatase activity
CEQ03_RS01520	COG1535	isochorismatase
CEQ03_RS01525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CEQ03_RS01525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEQ03_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS01550	COG2885	chlorophyll binding
CEQ03_RS01570	COG2194	sulfuric ester hydrolase activity
CEQ03_RS01580	COG2205	protein histidine kinase activity
CEQ03_RS01620	COG2207	Transcriptional regulator
CEQ03_RS01670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEQ03_RS01675	COG0315	cyclic pyranopterin monophosphate synthase activity
CEQ03_RS01675	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEQ03_RS01680	COG0303	'Molybdopterin
CEQ03_RS01690	COG0314	molybdopterin synthase activity
CEQ03_RS01695	COG0746	molybdenum cofactor guanylyltransferase activity
CEQ03_RS01705	COG2223	nitrite transmembrane transporter activity
CEQ03_RS01710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEQ03_RS01715	COG1140	nitrate reductase beta subunit
CEQ03_RS01720	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEQ03_RS01725	COG2181	nitrate reductase activity
CEQ03_RS01730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ03_RS01745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ03_RS01750	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEQ03_RS01755	COG4149	molybdate abc transporter
CEQ03_RS01760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEQ03_RS01765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ03_RS01770	COG0840	transmembrane signaling receptor activity
CEQ03_RS01780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEQ03_RS01785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEQ03_RS01885	COG3415	Transposase
CEQ03_RS01885	COG2801	Transposase and inactivated derivatives
CEQ03_RS01930	COG0811	peptide transport
CEQ03_RS01960	COG1335	isochorismatase
CEQ03_RS01965	COG1335	isochorismatase
CEQ03_RS02010	COG2202	Pas domain
CEQ03_RS02010	COG3920	Histidine kinase
CEQ03_RS02030	COG0477	Major facilitator Superfamily
CEQ03_RS02045	COG3537	Alpha-1,2-mannosidase
CEQ03_RS02050	COG0642	Histidine kinase
CEQ03_RS02075	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS02080	COG0583	DNA-binding transcription factor activity
CEQ03_RS02085	COG5002	protein histidine kinase activity
CEQ03_RS02100	COG2372	response to copper ion
CEQ03_RS02120	COG0656	L-ascorbic acid biosynthetic process
CEQ03_RS02125	COG0583	DNA-binding transcription factor activity
CEQ03_RS02140	COG1136	(ABC) transporter
CEQ03_RS02165	COG0477	Major facilitator Superfamily
CEQ03_RS02190	COG0243	molybdopterin cofactor binding
CEQ03_RS02245	COG4566	intracellular signal transduction
CEQ03_RS02250	COG4191	Histidine kinase
CEQ03_RS02255	COG1285	pathogenesis
CEQ03_RS02260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEQ03_RS02290	COG5002	protein histidine kinase activity
CEQ03_RS02305	COG4774	siderophore transport
CEQ03_RS02315	COG3214	Protein conserved in bacteria
CEQ03_RS02325	COG2205	protein histidine kinase activity
CEQ03_RS02330	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS02340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS02345	COG0577	efflux transmembrane transporter activity
CEQ03_RS02345	COG1136	(ABC) transporter
CEQ03_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS02365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ03_RS02370	COG0366	Alpha amylase catalytic
CEQ03_RS02375	COG0708	Exodeoxyribonuclease III
CEQ03_RS02475	COG0583	DNA-binding transcription factor activity
CEQ03_RS02495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ03_RS02525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ03_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS02540	COG2271	Major facilitator Superfamily
CEQ03_RS02560	COG2186	Transcriptional regulator
CEQ03_RS02575	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ03_RS02585	COG0642	Histidine kinase
CEQ03_RS02640	COG0583	DNA-binding transcription factor activity
CEQ03_RS02645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ03_RS02670	COG0583	DNA-binding transcription factor activity
CEQ03_RS02675	COG2828	Protein conserved in bacteria
CEQ03_RS02690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEQ03_RS02705	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CEQ03_RS02730	COG1063	alcohol dehydrogenase
CEQ03_RS02750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ03_RS02775	COG3685	Protein conserved in bacteria
CEQ03_RS02780	COG3546	catalase activity
CEQ03_RS02815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS02830	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ03_RS02850	COG2086	electron transfer activity
CEQ03_RS02865	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS02875	COG1024	Enoyl-CoA hydratase
CEQ03_RS03005	COG2205	protein histidine kinase activity
CEQ03_RS03010	COG0454	-acetyltransferase
CEQ03_RS03010	COG0456	acetyltransferase
CEQ03_RS03020	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CEQ03_RS03030	COG4251	negative regulation of phosphorylation
CEQ03_RS03035	COG0784	Response regulator, receiver
CEQ03_RS03055	COG1595	DNA-templated transcription, initiation
CEQ03_RS03070	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CEQ03_RS03080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ03_RS03125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ03_RS03135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEQ03_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ03_RS03145	COG4558	Periplasmic binding protein
CEQ03_RS03155	COG2819	hydrolase of the alpha beta superfamily
CEQ03_RS03170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ03_RS03185	COG1674	ftsk spoiiie
CEQ03_RS03190	COG0492	ferredoxin-NADP+ reductase activity
CEQ03_RS03235	COG0542	response to heat
CEQ03_RS03250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEQ03_RS03265	COG0482	sulfurtransferase activity
CEQ03_RS03270	COG2915	High frequency lysogenization protein hflD homolog
CEQ03_RS03315	COG5002	protein histidine kinase activity
CEQ03_RS03335	COG0835	chemotaxis
CEQ03_RS03335	COG0784	Response regulator, receiver
CEQ03_RS03340	COG1815	bacterial-type flagellum-dependent cell motility
CEQ03_RS03360	COG4787	bacterial-type flagellum-dependent cell motility
CEQ03_RS03370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEQ03_RS03385	COG1256	bacterial-type flagellum assembly
CEQ03_RS03405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEQ03_RS03425	COG2197	response regulator
CEQ03_RS03455	COG1677	Flagellar hook-basal body complex protein FliE
CEQ03_RS03505	COG3190	flagellar
CEQ03_RS03515	COG1987	bacterial-type flagellum assembly
CEQ03_RS03535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEQ03_RS03540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEQ03_RS03565	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEQ03_RS03570	COG0643	Histidine kinase
CEQ03_RS03570	COG0784	Response regulator, receiver
CEQ03_RS03570	COG2198	Histidine kinase
CEQ03_RS03575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEQ03_RS03580	COG1360	Flagellar Motor Protein
CEQ03_RS03590	COG0835	chemotaxis
CEQ03_RS03600	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS03610	COG0840	transmembrane signaling receptor activity
CEQ03_RS03615	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEQ03_RS03620	COG0835	chemotaxis
CEQ03_RS03630	COG0840	transmembrane signaling receptor activity
CEQ03_RS03635	COG0840	transmembrane signaling receptor activity
CEQ03_RS03645	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEQ03_RS03690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ03_RS03695	COG1309	transcriptional regulator
CEQ03_RS03700	COG1012	belongs to the aldehyde dehydrogenase family
CEQ03_RS03705	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CEQ03_RS03710	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ03_RS03720	COG2198	Histidine kinase
CEQ03_RS03720	COG2205	protein histidine kinase activity
CEQ03_RS03720	COG0784	Response regulator, receiver
CEQ03_RS03740	COG1012	belongs to the aldehyde dehydrogenase family
CEQ03_RS03755	COG3279	Response regulator of the LytR AlgR family
CEQ03_RS03770	COG4676	Protein conserved in bacteria
CEQ03_RS03775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ03_RS03790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ03_RS03795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ03_RS03800	COG0505	Belongs to the CarA family
CEQ03_RS03805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEQ03_RS03820	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ03_RS03865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ03_RS03880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS03890	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS03895	COG2205	protein histidine kinase activity
CEQ03_RS03910	COG0277	FAD linked oxidase domain protein
CEQ03_RS03915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ03_RS03925	COG0531	amino acid
CEQ03_RS03930	COG0531	amino acid
CEQ03_RS03940	COG0235	Class ii aldolase
CEQ03_RS03945	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CEQ03_RS03950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CEQ03_RS03965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ03_RS03975	COG1609	Transcriptional regulator
CEQ03_RS03980	COG3537	Alpha-1,2-mannosidase
CEQ03_RS03995	COG0789	Transcriptional regulator
CEQ03_RS04010	COG3142	Participates in the control of copper homeostasis
CEQ03_RS04015	COG1446	asparaginase
CEQ03_RS04035	COG0140	phosphoribosyl-ATP diphosphatase activity
CEQ03_RS04035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEQ03_RS04040	COG0107	imidazoleglycerol-phosphate synthase activity
CEQ03_RS04045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEQ03_RS04050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEQ03_RS04055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ03_RS04055	COG0131	Imidazoleglycerol-phosphate dehydratase
CEQ03_RS04060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ03_RS04065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEQ03_RS04070	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEQ03_RS04080	COG0124	histidyl-tRNA synthetase
CEQ03_RS04085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ03_RS04095	COG0083	homoserine kinase activity
CEQ03_RS04100	COG0527	aspartate kinase activity
CEQ03_RS04100	COG0460	homoserine dehydrogenase
CEQ03_RS04135	COG0640	Transcriptional regulator
CEQ03_RS04140	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS04150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ03_RS04155	COG2205	protein histidine kinase activity
CEQ03_RS04155	COG4999	Histidine kinase
CEQ03_RS04155	COG3850	Histidine kinase
CEQ03_RS04155	COG3437	response regulator, receiver
CEQ03_RS04160	COG0784	Response regulator, receiver
CEQ03_RS04160	COG4191	Histidine kinase
CEQ03_RS04205	COG1012	belongs to the aldehyde dehydrogenase family
CEQ03_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS04225	COG0167	dihydroorotate dehydrogenase activity
CEQ03_RS04230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ03_RS04235	COG0697	spore germination
CEQ03_RS04250	COG1309	transcriptional regulator
CEQ03_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS04285	COG0477	Major facilitator Superfamily
CEQ03_RS04290	COG0583	DNA-binding transcription factor activity
CEQ03_RS04295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEQ03_RS04325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ03_RS04330	COG1126	abc transporter atp-binding protein
CEQ03_RS04340	COG1473	amidohydrolase
CEQ03_RS04345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ03_RS04350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ03_RS04360	COG0431	NADPH-dependent FMN reductase
CEQ03_RS04365	COG4206	TonB-dependent receptor
CEQ03_RS04395	COG4716	Myosin-crossreactive antigen
CEQ03_RS04410	COG0640	Transcriptional regulator
CEQ03_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS04465	COG0583	DNA-binding transcription factor activity
CEQ03_RS04500	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ03_RS04500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ03_RS04515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ03_RS04515	COG0475	glutathione-regulated potassium exporter activity
CEQ03_RS04520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ03_RS04540	COG1160	GTP binding
CEQ03_RS04545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ03_RS04555	COG1426	Protein conserved in bacteria
CEQ03_RS04555	COG1426	Protein conserved in bacteria
CEQ03_RS04565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEQ03_RS04570	COG0105	UTP biosynthetic process
CEQ03_RS04580	COG1024	Enoyl-CoA hydratase
CEQ03_RS04580	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ03_RS04585	COG0183	Belongs to the thiolase family
CEQ03_RS04590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEQ03_RS04600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ03_RS04605	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEQ03_RS04615	COG0776	regulation of translation
CEQ03_RS04625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ03_RS04630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ03_RS04640	COG2957	Belongs to the agmatine deiminase family
CEQ03_RS04645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ03_RS04660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS04685	COG0488	(ABC) transporter
CEQ03_RS04690	COG0583	DNA-binding transcription factor activity
CEQ03_RS04700	COG0513	Belongs to the DEAD box helicase family
CEQ03_RS04705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ03_RS04715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEQ03_RS04720	COG0625	glutathione transferase activity
CEQ03_RS04740	COG4681	YaeQ
CEQ03_RS04745	COG2081	HI0933 family
CEQ03_RS04755	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ03_RS04765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ03_RS04775	COG0343	queuine tRNA-ribosyltransferase activity
CEQ03_RS04780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEQ03_RS04785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ03_RS04815	COG1132	(ABC) transporter
CEQ03_RS04825	COG1605	Chorismate mutase
CEQ03_RS04825	COG0287	Prephenate dehydrogenase
CEQ03_RS04830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CEQ03_RS04835	COG2223	nitrite transmembrane transporter activity
CEQ03_RS04840	COG2207	Transcriptional regulator
CEQ03_RS04845	COG0484	heat shock protein binding
CEQ03_RS04850	COG0443	Heat shock 70 kDa protein
CEQ03_RS04855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ03_RS04860	COG1420	regulation of RNA biosynthetic process
CEQ03_RS04865	COG0497	DNA recombination
CEQ03_RS04870	COG0583	DNA-binding transcription factor activity
CEQ03_RS05095	COG2974	May be involved in recombination
CEQ03_RS05110	COG0735	belongs to the Fur family
CEQ03_RS05115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ03_RS05120	COG2914	Belongs to the UPF0125 (RnfH) family
CEQ03_RS05130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEQ03_RS05535	COG0582	viral genome integration into host DNA
CEQ03_RS05550	COG2204	response regulator
CEQ03_RS05705	COG0583	DNA-binding transcription factor activity
CEQ03_RS05710	COG2885	chlorophyll binding
CEQ03_RS05715	COG0415	Belongs to the DNA photolyase family
CEQ03_RS05725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEQ03_RS05745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ03_RS05765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ03_RS05770	COG0405	Gamma-glutamyltransferase
CEQ03_RS05775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ03_RS05785	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ03_RS05790	COG0742	ribosomal rna small subunit methyltransferase
CEQ03_RS05805	COG0552	protein localization to endoplasmic reticulum
CEQ03_RS05815	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEQ03_RS05830	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ03_RS05850	COG1053	succinate dehydrogenase
CEQ03_RS05855	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEQ03_RS05860	COG2009	succinate dehydrogenase
CEQ03_RS05885	COG0837	glucose binding
CEQ03_RS05895	COG0129	dihydroxy-acid dehydratase activity
CEQ03_RS05900	COG0800	Aldolase
CEQ03_RS05910	COG0671	phosphoesterase, PA-phosphatase related
CEQ03_RS05925	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CEQ03_RS05930	COG0166	Belongs to the GPI family
CEQ03_RS05935	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEQ03_RS05945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEQ03_RS05950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEQ03_RS05955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ03_RS05960	COG0617	tRNA 3'-terminal CCA addition
CEQ03_RS05970	COG0477	Major facilitator Superfamily
CEQ03_RS05975	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEQ03_RS05985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEQ03_RS05995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEQ03_RS06000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEQ03_RS06015	COG0351	phosphomethylpyrimidine kinase
CEQ03_RS06015	COG0352	thiamine-phosphate diphosphorylase activity
CEQ03_RS06040	COG0583	DNA-binding transcription factor activity
CEQ03_RS06045	COG1741	Belongs to the pirin family
CEQ03_RS06060	COG2223	nitrite transmembrane transporter activity
CEQ03_RS06075	COG3258	Cytochrome c
CEQ03_RS06090	COG3540	Alkaline phosphatase
CEQ03_RS06140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEQ03_RS06145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ03_RS06150	COG2137	regulation of response to DNA damage stimulus
CEQ03_RS06155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ03_RS06160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEQ03_RS06165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEQ03_RS06170	COG1546	Belongs to the CinA family
CEQ03_RS06180	COG1923	regulation of RNA biosynthetic process
CEQ03_RS06185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEQ03_RS06190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEQ03_RS06205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ03_RS06210	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEQ03_RS06215	COG1534	Rna-binding protein
CEQ03_RS06240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEQ03_RS06245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEQ03_RS06250	COG2840	Smr protein MutS2
CEQ03_RS06260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEQ03_RS06265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEQ03_RS06270	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEQ03_RS06275	COG0148	phosphopyruvate hydratase activity
CEQ03_RS06290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEQ03_RS06295	COG0504	CTP synthase activity
CEQ03_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ03_RS06330	COG1253	flavin adenine dinucleotide binding
CEQ03_RS06345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ03_RS06350	COG1054	Belongs to the UPF0176 family
CEQ03_RS06375	COG0069	glutamate synthase activity
CEQ03_RS06380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ03_RS06395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ03_RS06430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEQ03_RS06435	COG4977	sequence-specific DNA binding
CEQ03_RS06435	COG1917	Cupin 2, conserved barrel domain protein
CEQ03_RS06455	COG0583	DNA-binding transcription factor activity
CEQ03_RS06490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEQ03_RS06595	COG0577	efflux transmembrane transporter activity
CEQ03_RS06595	COG1136	(ABC) transporter
CEQ03_RS06630	COG0322	excinuclease ABC activity
CEQ03_RS06640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ03_RS06645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEQ03_RS06650	COG1663	tetraacyldisaccharide 4'-kinase activity
CEQ03_RS06665	COG0811	peptide transport
CEQ03_RS06685	COG3713	MltA-interacting MipA family protein
CEQ03_RS06720	COG0556	nucleotide-excision repair
CEQ03_RS06765	COG1611	Belongs to the LOG family
CEQ03_RS06780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEQ03_RS06790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEQ03_RS06825	COG2969	positive regulation of protein catabolic process
CEQ03_RS06830	COG0625	glutathione transferase activity
CEQ03_RS06835	COG2857	Cytochrome c1
CEQ03_RS06840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEQ03_RS06845	COG0723	plastoquinol--plastocyanin reductase activity
CEQ03_RS06850	COG0741	lytic transglycosylase activity
CEQ03_RS06865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ03_RS06870	COG0842	Transport permease protein
CEQ03_RS06875	COG1131	(ABC) transporter
CEQ03_RS06880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS06885	COG1702	phosphate starvation-inducible protein PhoH
CEQ03_RS06890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEQ03_RS06910	COG4535	Mg2 and Co2 transporter CorC
CEQ03_RS06925	COG1012	belongs to the aldehyde dehydrogenase family
CEQ03_RS06930	COG1177	transmembrane transport
CEQ03_RS06935	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ03_RS06940	COG3842	ATPase activity
CEQ03_RS06945	COG2072	flavoprotein involved in K transport
CEQ03_RS06955	COG0174	glutamine synthetase
CEQ03_RS06960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CEQ03_RS06965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ03_RS06985	COG2703	oxygen carrier activity
CEQ03_RS06990	COG0477	Major facilitator Superfamily
CEQ03_RS07005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEQ03_RS07015	COG2733	membrane
CEQ03_RS07035	COG0116	Belongs to the methyltransferase superfamily
CEQ03_RS07035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ03_RS07055	COG0494	nUDIX hydrolase
CEQ03_RS07065	COG1024	Enoyl-CoA hydratase
CEQ03_RS07075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ03_RS07085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ03_RS07090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ03_RS07095	COG0573	inorganic phosphate transmembrane transporter activity
CEQ03_RS07100	COG0581	inorganic phosphate transmembrane transporter activity
CEQ03_RS07110	COG0704	Plays a role in the regulation of phosphate uptake
CEQ03_RS07120	COG3220	belongs to the UPF0276 family
CEQ03_RS07130	COG2259	Doxx family
CEQ03_RS07135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ03_RS07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS07160	COG0577	efflux transmembrane transporter activity
CEQ03_RS07160	COG1136	(ABC) transporter
CEQ03_RS07165	COG1538	Outer membrane efflux protein
CEQ03_RS07170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ03_RS07180	COG0557	exoribonuclease II activity
CEQ03_RS07210	COG0583	DNA-binding transcription factor activity
CEQ03_RS07225	COG2814	Major facilitator Superfamily
CEQ03_RS07230	COG1566	PFAM secretion protein HlyD family protein
CEQ03_RS07265	COG0475	glutathione-regulated potassium exporter activity
CEQ03_RS07270	COG0367	asparagine synthase
CEQ03_RS07275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ03_RS07280	COG1393	Belongs to the ArsC family
CEQ03_RS07295	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEQ03_RS07315	COG3188	usher protein
CEQ03_RS07335	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ03_RS07340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ03_RS07350	COG0528	UMP kinase activity
CEQ03_RS07355	COG0233	cytoplasmic translational termination
CEQ03_RS07360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ03_RS07365	COG0575	Belongs to the CDS family
CEQ03_RS07370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEQ03_RS07375	COG0750	zinc metalloprotease
CEQ03_RS07380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ03_RS07385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ03_RS07395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ03_RS07400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ03_RS07420	COG0825	malonyl-CoA metabolic process
CEQ03_RS07425	COG1981	membrane
CEQ03_RS07445	COG1695	Transcriptional regulator
CEQ03_RS07495	COG1132	(ABC) transporter
CEQ03_RS07520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ03_RS07530	COG1187	pseudouridine synthase activity
CEQ03_RS07585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ03_RS07625	COG0735	belongs to the Fur family
CEQ03_RS07630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ03_RS07645	COG4452	Inner membrane protein CreD
CEQ03_RS07650	COG2205	protein histidine kinase activity
CEQ03_RS07655	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS07660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEQ03_RS07670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ03_RS07680	COG3415	Transposase
CEQ03_RS07680	COG2801	Transposase and inactivated derivatives
CEQ03_RS07685	COG3590	peptidase
CEQ03_RS07690	COG0588	phosphoglycerate mutase activity
CEQ03_RS07720	COG3706	GGDEF domain
CEQ03_RS07725	COG2814	Major facilitator Superfamily
CEQ03_RS07750	COG1647	Serine aminopeptidase, S33
CEQ03_RS07760	COG2076	Multidrug Resistance protein
CEQ03_RS07775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEQ03_RS07800	COG0024	Methionine aminopeptidase
CEQ03_RS07820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS07840	COG0840	transmembrane signaling receptor activity
CEQ03_RS08080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ03_RS08090	COG0753	catalase activity
CEQ03_RS08110	COG0534	Mate efflux family protein
CEQ03_RS08130	COG0335	large ribosomal subunit rRNA binding
CEQ03_RS08135	COG0336	Belongs to the RNA methyltransferase TrmD family
CEQ03_RS08140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEQ03_RS08145	COG0228	four-way junction DNA binding
CEQ03_RS08160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ03_RS08180	COG0326	Molecular chaperone. Has ATPase activity
CEQ03_RS08195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEQ03_RS08200	COG1845	cytochrome c oxidase, subunit III
CEQ03_RS08205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEQ03_RS08240	COG3209	COG3209 Rhs family protein
CEQ03_RS08250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ03_RS08270	COG4206	TonB-dependent receptor
CEQ03_RS08295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEQ03_RS08305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEQ03_RS08310	COG0196	riboflavin kinase activity
CEQ03_RS08315	COG0728	peptidoglycan biosynthetic process
CEQ03_RS08320	COG0268	Binds directly to 16S ribosomal RNA
CEQ03_RS08325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEQ03_RS08330	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ03_RS08335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEQ03_RS08340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ03_RS08345	COG0824	Thioesterase
CEQ03_RS08365	COG1946	Acyl-CoA thioesterase
CEQ03_RS08375	COG1595	DNA-templated transcription, initiation
CEQ03_RS08385	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEQ03_RS08395	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEQ03_RS08440	COG2197	response regulator
CEQ03_RS08445	COG4585	Histidine kinase
CEQ03_RS08460	COG2894	cell division
CEQ03_RS08465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEQ03_RS08480	COG0823	Involved in the tonB-independent uptake of proteins
CEQ03_RS08480	COG1506	peptidase
CEQ03_RS08485	COG1297	OPT oligopeptide transporter protein
CEQ03_RS08500	COG3104	oligopeptide transport
CEQ03_RS08525	COG0579	oxidoreductase
CEQ03_RS08540	COG3052	prosthetic group binding
CEQ03_RS08575	COG1802	Transcriptional regulator
CEQ03_RS08620	COG2259	Doxx family
CEQ03_RS08640	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CEQ03_RS08645	COG1408	metallophosphoesterase
CEQ03_RS08650	COG1253	flavin adenine dinucleotide binding
CEQ03_RS08655	COG3655	Transcriptional regulator
CEQ03_RS08670	COG0640	Transcriptional regulator
CEQ03_RS08710	COG1609	Transcriptional regulator
CEQ03_RS08725	COG0673	inositol 2-dehydrogenase activity
CEQ03_RS08760	COG0629	single-stranded DNA binding
CEQ03_RS08770	COG1131	(ABC) transporter
CEQ03_RS08805	COG2211	Major facilitator Superfamily
CEQ03_RS08805	COG2190	(PTS) system
CEQ03_RS08815	COG1082	Xylose isomerase domain protein TIM barrel
CEQ03_RS08825	COG0366	Alpha amylase catalytic
CEQ03_RS08830	COG0142	geranyltranstransferase activity
CEQ03_RS08855	COG0527	aspartate kinase activity
CEQ03_RS08860	COG0384	phenazine biosynthesis protein PhzF
CEQ03_RS08865	COG0384	phenazine biosynthesis protein PhzF
CEQ03_RS08870	COG1764	response to oxidative stress
CEQ03_RS08895	COG0693	protein deglycase activity
CEQ03_RS08905	COG1959	2 iron, 2 sulfur cluster binding
CEQ03_RS08910	COG0719	Fe-S assembly protein
CEQ03_RS08920	COG0396	ATPase activity
CEQ03_RS08925	COG0719	Fe-S assembly protein
CEQ03_RS08930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ03_RS08945	COG2146	nitrite reductase [NAD(P)H] activity
CEQ03_RS08955	COG4774	siderophore transport
CEQ03_RS08965	COG3128	pkhd-type hydroxylase
CEQ03_RS08970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEQ03_RS09000	COG1477	protein flavinylation
CEQ03_RS09005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ03_RS09025	COG1555	photosystem II stabilization
CEQ03_RS09035	COG2261	transglycosylase associated protein
CEQ03_RS09045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEQ03_RS09055	COG0628	permease
CEQ03_RS09065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ03_RS09085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEQ03_RS09105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ03_RS09120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEQ03_RS09135	COG1137	ATPase activity
CEQ03_RS09145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ03_RS09150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ03_RS09155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEQ03_RS09160	COG1660	Displays ATPase and GTPase activities
CEQ03_RS09175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ03_RS09180	COG2239	Acts as a magnesium transporter
CEQ03_RS09200	COG0540	Belongs to the ATCase OTCase family
CEQ03_RS09205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ03_RS09210	COG1678	Uncharacterized ACR, COG1678
CEQ03_RS09215	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CEQ03_RS09220	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ03_RS09245	COG0667	Aldo Keto reductase
CEQ03_RS09260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ03_RS09270	COG0583	DNA-binding transcription factor activity
CEQ03_RS09305	COG0477	Major facilitator Superfamily
CEQ03_RS09315	COG0697	spore germination
CEQ03_RS09320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ03_RS09325	COG0583	DNA-binding transcription factor activity
CEQ03_RS09335	COG2226	methyltransferase
CEQ03_RS09350	COG2223	nitrite transmembrane transporter activity
CEQ03_RS09365	COG4774	siderophore transport
CEQ03_RS09505	COG0582	viral genome integration into host DNA
CEQ03_RS09570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEQ03_RS09575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEQ03_RS09580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ03_RS09585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ03_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS09600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEQ03_RS09610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ03_RS09615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEQ03_RS09620	COG1399	metal-binding, possibly nucleic acid-binding protein
CEQ03_RS09635	COG0714	Associated with various cellular activities
CEQ03_RS09655	COG0537	adenosine 5'-monophosphoramidase activity
CEQ03_RS09665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEQ03_RS09695	COG2076	Multidrug Resistance protein
CEQ03_RS09710	COG1234	tRNA 3'-trailer cleavage
CEQ03_RS09715	COG3642	lipopolysaccharide core region biosynthetic process
CEQ03_RS09720	COG0859	PFAM glycosyl transferase family 9
CEQ03_RS09735	COG0582	viral genome integration into host DNA
CEQ03_RS09775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ03_RS09780	COG2194	sulfuric ester hydrolase activity
CEQ03_RS09800	COG1063	alcohol dehydrogenase
CEQ03_RS09830	COG4983	Phage plasmid primase, P4 family domain protein
CEQ03_RS09850	COG5377	YqaJ viral recombinase family
CEQ03_RS09920	COG0631	protein serine/threonine phosphatase activity
CEQ03_RS09925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ03_RS09930	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ03_RS09940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ03_RS09945	COG1388	LysM domain
CEQ03_RS09945	COG3942	CHAP domain
CEQ03_RS09990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEQ03_RS09995	COG0740	serine-type endopeptidase activity
CEQ03_RS10000	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ03_RS10065	COG0473	3-isopropylmalate dehydrogenase activity
CEQ03_RS10080	COG4783	chaperone-mediated protein folding
CEQ03_RS10095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEQ03_RS10100	COG0248	Ppx GppA phosphatase
CEQ03_RS10110	COG0438	transferase activity, transferring glycosyl groups
CEQ03_RS10120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ03_RS10125	COG3291	Pkd domain containing protein
CEQ03_RS10135	COG2833	Protein of unknown function (DUF455)
CEQ03_RS10155	COG0285	dihydrofolate synthase activity
CEQ03_RS10160	COG0406	alpha-ribazole phosphatase activity
CEQ03_RS10175	COG1063	alcohol dehydrogenase
CEQ03_RS10195	COG1187	pseudouridine synthase activity
CEQ03_RS10205	COG3344	reverse transcriptase
CEQ03_RS10215	COG0604	alcohol dehydrogenase
CEQ03_RS10220	COG2364	Membrane
CEQ03_RS10225	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ03_RS10225	COG1902	pentaerythritol trinitrate reductase activity
CEQ03_RS10235	COG0625	glutathione transferase activity
CEQ03_RS10255	COG0564	pseudouridine synthase activity
CEQ03_RS10260	COG0039	L-malate dehydrogenase activity
CEQ03_RS10265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ03_RS10280	COG0154	amidase activity
CEQ03_RS10290	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CEQ03_RS10305	COG0203	ribosomal protein L17
CEQ03_RS10310	COG0202	RNA polymerase activity
CEQ03_RS10315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ03_RS10320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ03_RS10325	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ03_RS10330	COG0201	protein transport
CEQ03_RS10335	COG0200	Binds to the 23S rRNA
CEQ03_RS10340	COG1841	ribosomal large subunit assembly
CEQ03_RS10345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEQ03_RS10350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEQ03_RS10355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ03_RS10360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ03_RS10365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ03_RS10370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEQ03_RS10375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEQ03_RS10380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEQ03_RS10385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ03_RS10390	COG0255	Belongs to the universal ribosomal protein uL29 family
CEQ03_RS10395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEQ03_RS10400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEQ03_RS10405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEQ03_RS10410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEQ03_RS10415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEQ03_RS10420	COG0089	rRNA binding
CEQ03_RS10425	COG0088	Forms part of the polypeptide exit tunnel
CEQ03_RS10430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEQ03_RS10435	COG0051	transcription antitermination factor activity, RNA binding
CEQ03_RS10440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ03_RS10445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ03_RS10450	COG0049	tRNA binding
CEQ03_RS10455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEQ03_RS10460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ03_RS10470	COG0222	ribosome binding
CEQ03_RS10475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ03_RS10485	COG0081	regulation of translation
CEQ03_RS10490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEQ03_RS10495	COG0250	Participates in transcription elongation, termination and antitermination
CEQ03_RS10510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ03_RS10535	COG4242	Belongs to the peptidase S51 family
CEQ03_RS10540	COG4206	TonB-dependent receptor
CEQ03_RS10545	COG2205	protein histidine kinase activity
CEQ03_RS10545	COG0784	Response regulator, receiver
CEQ03_RS10555	COG2205	protein histidine kinase activity
CEQ03_RS10555	COG0784	Response regulator, receiver
CEQ03_RS10560	COG2197	response regulator
CEQ03_RS10570	COG0012	GTP binding
CEQ03_RS10575	COG0193	aminoacyl-tRNA hydrolase activity
CEQ03_RS10580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEQ03_RS10585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ03_RS10595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEQ03_RS10610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEQ03_RS10615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ03_RS10630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ03_RS10635	COG1295	ribonuclease BN
CEQ03_RS10655	COG1404	Belongs to the peptidase S8 family
CEQ03_RS10660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ03_RS10675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEQ03_RS10700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEQ03_RS10715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ03_RS10715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ03_RS10755	COG3634	alkyl hydroperoxide reductase activity
CEQ03_RS10760	COG0583	DNA-binding transcription factor activity
CEQ03_RS10765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ03_RS10780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ03_RS10790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ03_RS10810	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CEQ03_RS10815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEQ03_RS10820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ03_RS10825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ03_RS10835	COG2096	Adenosyltransferase
CEQ03_RS10845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEQ03_RS10855	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEQ03_RS10860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ03_RS10865	COG2967	ApaG domain
CEQ03_RS10870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEQ03_RS10875	COG3738	Protein conserved in bacteria
CEQ03_RS10885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ03_RS10890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEQ03_RS10905	COG1704	LemA family
CEQ03_RS10910	COG2814	Major facilitator Superfamily
CEQ03_RS10915	COG0861	Integral membrane protein TerC family
CEQ03_RS10920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ03_RS10930	COG0642	Histidine kinase
CEQ03_RS10945	COG4181	ATPase activity
CEQ03_RS10950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEQ03_RS10965	COG4771	TonB-dependent receptor
CEQ03_RS10975	COG0667	Aldo Keto reductase
CEQ03_RS10980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ03_RS10985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ03_RS11010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ03_RS11015	COG4106	trans-aconitate 2-methyltransferase activity
CEQ03_RS11045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ03_RS11050	COG1607	acyl-coa hydrolase
CEQ03_RS11055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEQ03_RS11065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CEQ03_RS11070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ03_RS11090	COG3279	Response regulator of the LytR AlgR family
CEQ03_RS11095	COG3275	phosphorelay sensor kinase activity
CEQ03_RS11105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ03_RS11115	COG0494	nUDIX hydrolase
CEQ03_RS11120	COG0653	protein targeting
CEQ03_RS11125	COG0739	heme binding
CEQ03_RS11135	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEQ03_RS11140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEQ03_RS11150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEQ03_RS11155	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ03_RS11160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ03_RS11180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ03_RS11185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ03_RS11195	COG3116	cell division
CEQ03_RS11200	COG0275	rRNA processing
CEQ03_RS11205	COG2001	Belongs to the MraZ family
CEQ03_RS11240	COG1988	membrane-bound metal-dependent
CEQ03_RS11245	COG0277	FAD linked oxidase domain protein
CEQ03_RS11250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEQ03_RS11250	COG2755	lipolytic protein G-D-S-L family
CEQ03_RS11275	COG3121	Chaperone
CEQ03_RS11285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ03_RS11290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEQ03_RS11325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ03_RS11325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ03_RS11330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEQ03_RS11350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ03_RS11360	COG0488	(ABC) transporter
CEQ03_RS11365	COG2252	PERMEase
CEQ03_RS11380	COG1215	transferase activity, transferring glycosyl groups
CEQ03_RS11390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEQ03_RS11405	COG3121	Chaperone
CEQ03_RS11410	COG3539	Fimbrial protein
CEQ03_RS11420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEQ03_RS11435	COG1450	Type ii and iii secretion system protein
CEQ03_RS11450	COG3166	PFAM Fimbrial assembly family protein
CEQ03_RS11455	COG3156	type II secretion system protein K
CEQ03_RS11460	COG4795	General secretion pathway protein
CEQ03_RS11465	COG2165	general secretion pathway protein
CEQ03_RS11470	COG4970	Tfp pilus assembly protein FimT
CEQ03_RS11475	COG2165	general secretion pathway protein
CEQ03_RS11480	COG1459	type II secretion system
CEQ03_RS11485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ03_RS11490	COG1404	Belongs to the peptidase S8 family
CEQ03_RS11495	COG5295	Hep Hag repeat protein
CEQ03_RS11500	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ03_RS11500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ03_RS11510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ03_RS11515	COG4974	Belongs to the 'phage' integrase family
CEQ03_RS11525	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ03_RS11535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ03_RS11545	COG0525	valine-tRNA ligase activity
CEQ03_RS11555	COG0456	acetyltransferase
CEQ03_RS11565	COG1183	phosphatidylcholine synthase activity
CEQ03_RS11575	COG0442	prolyl-tRNA aminoacylation
CEQ03_RS11590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEQ03_RS11595	COG1127	ABC transporter
CEQ03_RS11625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEQ03_RS11630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ03_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ03_RS11710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ03_RS11725	COG0626	cystathionine gamma-synthase activity
CEQ03_RS11765	COG0625	glutathione transferase activity
CEQ03_RS11775	COG0513	Belongs to the DEAD box helicase family
CEQ03_RS11790	COG0720	synthase
CEQ03_RS11800	COG0367	asparagine synthase
CEQ03_RS11805	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS11810	COG2205	protein histidine kinase activity
CEQ03_RS11815	COG2205	protein histidine kinase activity
CEQ03_RS11820	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS11825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ03_RS11830	COG0785	Cytochrome C biogenesis protein
CEQ03_RS11830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ03_RS11835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ03_RS11840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ03_RS11845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEQ03_RS11850	COG1956	GAF domain-containing protein
CEQ03_RS11875	COG2226	methyltransferase
CEQ03_RS11880	COG0583	DNA-binding transcription factor activity
CEQ03_RS11895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ03_RS11900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ03_RS11910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ03_RS11915	COG1187	pseudouridine synthase activity
CEQ03_RS11920	COG2813	Specifically methylates the guanine in position
CEQ03_RS11935	COG5002	protein histidine kinase activity
CEQ03_RS11950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ03_RS11980	COG1360	Flagellar Motor Protein
CEQ03_RS12005	COG0025	NhaP-type Na H and K H
CEQ03_RS12010	COG3384	dioxygenase
CEQ03_RS12020	COG0583	DNA-binding transcription factor activity
CEQ03_RS12030	COG3590	peptidase
CEQ03_RS12035	COG2814	Major facilitator Superfamily
CEQ03_RS12045	COG1309	transcriptional regulator
CEQ03_RS12065	COG3279	Response regulator of the LytR AlgR family
CEQ03_RS12070	COG3275	phosphorelay sensor kinase activity
CEQ03_RS12100	COG4941	Belongs to the sigma-70 factor family
CEQ03_RS12105	COG5507	3-demethylubiquinone-9 3-methyltransferase
CEQ03_RS12115	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CEQ03_RS12140	COG0741	lytic transglycosylase activity
CEQ03_RS12145	COG1113	amino acid transport
CEQ03_RS12150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEQ03_RS12155	COG2814	Major facilitator Superfamily
CEQ03_RS12165	COG0583	DNA-binding transcription factor activity
CEQ03_RS12170	COG0488	(ABC) transporter
CEQ03_RS12235	COG2267	carboxylic ester hydrolase activity
CEQ03_RS12310	COG2375	cellular response to nickel ion
CEQ03_RS12325	COG2353	YceI-like domain
CEQ03_RS12330	COG0778	Nitroreductase
CEQ03_RS12360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ03_RS12365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEQ03_RS12375	COG5383	Protein conserved in bacteria
CEQ03_RS12405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEQ03_RS12425	COG4948	Mandelate Racemase Muconate Lactonizing
CEQ03_RS12430	COG1737	Transcriptional regulator
CEQ03_RS12440	COG0531	amino acid
CEQ03_RS12450	COG4682	membrane
CEQ03_RS12455	COG2133	pyrroloquinoline quinone binding
CEQ03_RS12470	COG0668	transmembrane transport
CEQ03_RS12475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEQ03_RS12485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEQ03_RS12500	COG1295	ribonuclease BN
CEQ03_RS12505	COG0358	DNA primase activity
CEQ03_RS12525	COG0109	protoheme IX farnesyltransferase activity
CEQ03_RS12570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEQ03_RS12605	COG0793	Belongs to the peptidase S41A family
CEQ03_RS12610	COG4942	peptidase
CEQ03_RS12620	COG2234	aminopeptidase activity
CEQ03_RS12680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEQ03_RS12685	COG0739	heme binding
CEQ03_RS12705	COG0708	Exodeoxyribonuclease III
CEQ03_RS12710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEQ03_RS12725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CEQ03_RS12730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CEQ03_RS12740	COG2205	protein histidine kinase activity
CEQ03_RS12755	COG0756	dUTP diphosphatase activity
CEQ03_RS12760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ03_RS12765	COG2197	response regulator
CEQ03_RS12770	COG2003	Belongs to the UPF0758 family
CEQ03_RS12775	COG0018	arginyl-trna synthetase
CEQ03_RS12785	COG4221	oxidoreductase activity
CEQ03_RS12795	COG4807	Protein conserved in bacteria
CEQ03_RS12800	COG0583	DNA-binding transcription factor activity
CEQ03_RS12805	COG2814	Major facilitator Superfamily
CEQ03_RS12820	COG2197	response regulator
CEQ03_RS12835	COG5507	3-demethylubiquinone-9 3-methyltransferase
CEQ03_RS12850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ03_RS12870	COG0628	permease
CEQ03_RS12885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ03_RS12890	COG0753	catalase activity
CEQ03_RS12900	COG2197	response regulator
CEQ03_RS12905	COG4585	Histidine kinase
CEQ03_RS12925	COG1136	(ABC) transporter
CEQ03_RS12935	COG0577	efflux transmembrane transporter activity
CEQ03_RS12935	COG1136	(ABC) transporter
CEQ03_RS12940	COG4206	TonB-dependent receptor
CEQ03_RS12950	COG0697	spore germination
CEQ03_RS12965	COG4152	abc transporter atp-binding protein
CEQ03_RS12975	COG0477	Major facilitator Superfamily
CEQ03_RS13000	COG0180	Tryptophanyl-tRNA synthetase
CEQ03_RS13010	COG3237	CsbD-like
CEQ03_RS13050	COG3657	addiction module killer protein
CEQ03_RS13065	COG0477	Major facilitator Superfamily
CEQ03_RS13080	COG0154	amidase activity
CEQ03_RS13085	COG0066	3-isopropylmalate dehydratase activity
CEQ03_RS13100	COG0840	transmembrane signaling receptor activity
CEQ03_RS13105	COG0840	transmembrane signaling receptor activity
CEQ03_RS13105	COG0840	transmembrane signaling receptor activity
CEQ03_RS13155	COG1902	pentaerythritol trinitrate reductase activity
CEQ03_RS13185	COG0582	viral genome integration into host DNA
CEQ03_RS13200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CEQ03_RS13205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEQ03_RS13205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEQ03_RS13215	COG3228	Belongs to the MtfA family
CEQ03_RS13235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ03_RS13260	COG1764	response to oxidative stress
CEQ03_RS13270	COG1024	Enoyl-CoA hydratase
CEQ03_RS13275	COG1024	Enoyl-CoA hydratase
CEQ03_RS13280	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS13290	COG1396	sequence-specific DNA binding
CEQ03_RS13290	COG3800	Transcriptional regulator
CEQ03_RS13300	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ03_RS13315	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ03_RS13320	COG1335	isochorismatase
CEQ03_RS13335	COG1902	pentaerythritol trinitrate reductase activity
CEQ03_RS13345	COG1607	acyl-coa hydrolase
CEQ03_RS13350	COG1280	lysine exporter protein (LysE YggA)
CEQ03_RS13360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ03_RS13375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEQ03_RS13385	COG0697	spore germination
CEQ03_RS13405	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS13410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEQ03_RS13435	COG3706	GGDEF domain
CEQ03_RS13440	COG2224	Isocitrate lyase
CEQ03_RS13445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEQ03_RS13450	COG0583	DNA-binding transcription factor activity
CEQ03_RS13455	COG0583	DNA-binding transcription factor activity
CEQ03_RS13460	COG2814	Major facilitator Superfamily
CEQ03_RS13465	COG0681	Belongs to the peptidase S26 family
CEQ03_RS13480	COG0339	signal peptide processing
CEQ03_RS13510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CEQ03_RS13515	COG1215	transferase activity, transferring glycosyl groups
CEQ03_RS13530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEQ03_RS13545	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ03_RS13555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ03_RS13560	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ03_RS13570	COG0596	Alpha beta hydrolase
CEQ03_RS13575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ03_RS13585	COG0612	Peptidase, M16
CEQ03_RS13595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEQ03_RS13600	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS13610	COG3474	cytochrome
CEQ03_RS13620	COG2197	response regulator
CEQ03_RS13660	COG2837	iron assimilation
CEQ03_RS13700	COG0431	NADPH-dependent FMN reductase
CEQ03_RS13710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ03_RS13715	COG0798	PFAM Bile acid sodium symporter
CEQ03_RS13735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ03_RS13740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CEQ03_RS13775	COG0183	Belongs to the thiolase family
CEQ03_RS13785	COG2032	superoxide dismutase activity
CEQ03_RS13790	COG2032	superoxide dismutase activity
CEQ03_RS13795	COG2204	response regulator
CEQ03_RS13800	COG3852	Histidine kinase
CEQ03_RS13815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEQ03_RS13825	COG3023	N-Acetylmuramoyl-L-alanine amidase
CEQ03_RS13830	COG0004	ammonium transporteR
CEQ03_RS13835	COG0347	Belongs to the P(II) protein family
CEQ03_RS13840	COG0174	glutamine synthetase
CEQ03_RS13845	COG1968	undecaprenyl-diphosphatase activity
CEQ03_RS13860	COG1881	PFAM PEBP family protein
CEQ03_RS13885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ03_RS13905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ03_RS13925	COG3550	peptidyl-serine autophosphorylation
CEQ03_RS13935	COG0312	modulator of DNA gyrase
CEQ03_RS13955	COG0714	Associated with various cellular activities
CEQ03_RS13990	COG1111	helicase
CEQ03_RS13990	COG1205	dead DEAH box helicase
CEQ03_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS14050	COG0070	glutamate synthase
CEQ03_RS14050	COG0067	glutamate synthase
CEQ03_RS14050	COG0069	glutamate synthase activity
CEQ03_RS14055	COG0493	'glutamate synthase
CEQ03_RS14065	COG1803	Methylglyoxal synthase
CEQ03_RS14075	COG2974	May be involved in recombination
CEQ03_RS14080	COG0037	tRNA processing
CEQ03_RS14090	COG2937	Belongs to the GPAT DAPAT family
CEQ03_RS14100	COG0284	orotidine-5'-phosphate decarboxylase activity
CEQ03_RS14105	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CEQ03_RS14110	COG3132	Protein of unknown function, DUF480
CEQ03_RS14120	COG0210	DNA helicase
CEQ03_RS14145	COG1476	TRANSCRIPTIONal
CEQ03_RS14160	COG1435	thymidine kinase activity
CEQ03_RS14165	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CEQ03_RS14170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEQ03_RS14185	COG1119	ATPase activity
CEQ03_RS14200	COG0671	phosphoesterase, PA-phosphatase related
CEQ03_RS14205	COG4771	TonB-dependent receptor
CEQ03_RS14215	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ03_RS14225	COG1522	sequence-specific DNA binding
CEQ03_RS14230	COG3186	Phenylalanine-4-hydroxylase
CEQ03_RS14250	COG0800	Aldolase
CEQ03_RS14285	COG4772	TonB-dependent receptor
CEQ03_RS14295	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEQ03_RS14340	COG0640	Transcriptional regulator
CEQ03_RS14360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ03_RS14360	COG3453	Protein conserved in bacteria
CEQ03_RS14375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ03_RS14395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEQ03_RS14410	COG0431	NADPH-dependent FMN reductase
CEQ03_RS14440	COG0659	secondary active sulfate transmembrane transporter activity
CEQ03_RS14545	COG0501	Belongs to the peptidase M48B family
CEQ03_RS14555	COG0187	DNA topoisomerase II activity
CEQ03_RS14560	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ03_RS14570	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEQ03_RS14575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEQ03_RS14580	COG0594	ribonuclease P activity
CEQ03_RS14585	COG0706	membrane insertase activity
CEQ03_RS14600	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ03_RS14610	COG0861	Integral membrane protein TerC family
CEQ03_RS14615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ03_RS14625	COG0531	amino acid
CEQ03_RS14645	COG0583	DNA-binding transcription factor activity
CEQ03_RS14650	COG0604	alcohol dehydrogenase
CEQ03_RS14660	COG1322	Protein conserved in bacteria
CEQ03_RS14670	COG0386	Belongs to the glutathione peroxidase family
CEQ03_RS14675	COG2853	Lipoprotein
CEQ03_RS14690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEQ03_RS14695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEQ03_RS14700	COG1127	ABC transporter
CEQ03_RS14705	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEQ03_RS14710	COG1074	ATP-dependent DNA helicase activity
CEQ03_RS14740	COG1566	PFAM secretion protein HlyD family protein
CEQ03_RS14755	COG0302	gtp cyclohydrolase
CEQ03_RS14785	COG3706	GGDEF domain
CEQ03_RS14790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEQ03_RS14795	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CEQ03_RS14800	COG2951	lytic endotransglycosylase activity
CEQ03_RS14815	COG3135	benzoate transporter
CEQ03_RS14875	COG0596	Alpha beta hydrolase
CEQ03_RS14875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEQ03_RS14880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEQ03_RS14890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ03_RS14900	COG0805	protein transport
CEQ03_RS14910	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ03_RS14910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ03_RS14915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ03_RS14920	COG0752	glycyl-tRNA synthetase alpha subunit
CEQ03_RS14930	COG0729	surface antigen
CEQ03_RS14935	COG2911	Protein conserved in bacteria
CEQ03_RS14945	COG0443	Heat shock 70 kDa protein
CEQ03_RS14955	COG0784	Response regulator, receiver
CEQ03_RS14955	COG2205	protein histidine kinase activity
CEQ03_RS14960	COG1971	Probably functions as a manganese efflux pump
CEQ03_RS15000	COG2091	lysine biosynthetic process via aminoadipic acid
CEQ03_RS15005	COG0357	Ribosomal RNA small subunit methyltransferase G
CEQ03_RS15010	COG1192	Involved in chromosome partitioning
CEQ03_RS15015	COG1475	DNA binding
CEQ03_RS15030	COG0463	Glycosyl transferase, family 2
CEQ03_RS15065	COG0251	oxidation-reduction process
CEQ03_RS15080	COG1819	glycosyl
CEQ03_RS15085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEQ03_RS15090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ03_RS15095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ03_RS15105	COG0210	DNA helicase
CEQ03_RS15125	COG0589	response to stress
CEQ03_RS15140	COG2323	membrane
CEQ03_RS15150	COG0408	coproporphyrinogen oxidase activity
CEQ03_RS15185	COG1595	DNA-templated transcription, initiation
CEQ03_RS15215	COG1271	oxidase subunit
CEQ03_RS15220	COG1294	oxidase, subunit
CEQ03_RS15230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ03_RS15235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ03_RS15250	COG0463	Glycosyl transferase, family 2
CEQ03_RS15260	COG2986	histidine ammonia-lyase
CEQ03_RS15300	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS15305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ03_RS15315	COG3100	YcgL domain-containing protein
CEQ03_RS15320	COG0666	response to abiotic stimulus
CEQ03_RS15320	COG3177	Filamentation induced by cAMP protein fic
CEQ03_RS15330	COG2239	Acts as a magnesium transporter
CEQ03_RS15335	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ03_RS15335	COG1042	CoA-binding domain protein
CEQ03_RS15335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ03_RS15340	COG0393	Putative heavy-metal-binding
CEQ03_RS15345	COG2267	carboxylic ester hydrolase activity
CEQ03_RS15355	COG2814	Major facilitator Superfamily
CEQ03_RS15360	COG0583	DNA-binding transcription factor activity
CEQ03_RS15365	COG0840	transmembrane signaling receptor activity
CEQ03_RS15380	COG1690	Belongs to the RtcB family
CEQ03_RS15395	COG0667	Aldo Keto reductase
CEQ03_RS15410	COG1187	pseudouridine synthase activity
CEQ03_RS15420	COG1643	Atp-dependent helicase
CEQ03_RS15435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ03_RS15460	COG0842	Transport permease protein
CEQ03_RS15465	COG1131	(ABC) transporter
CEQ03_RS15470	COG0543	2 iron, 2 sulfur cluster binding
CEQ03_RS15470	COG0633	Ferredoxin
CEQ03_RS15500	COG4555	ABC transporter
CEQ03_RS15515	COG2207	Transcriptional regulator
CEQ03_RS15535	COG0625	glutathione transferase activity
CEQ03_RS15565	COG3781	membrane
CEQ03_RS15585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ03_RS15595	COG1199	ATP-dependent helicase activity
CEQ03_RS15600	COG0129	dihydroxy-acid dehydratase activity
CEQ03_RS15615	COG0754	glutathionylspermidine amidase activity
CEQ03_RS15630	COG0714	Associated with various cellular activities
CEQ03_RS15655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEQ03_RS15660	COG3541	Predicted nucleotidyltransferase
CEQ03_RS15665	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS15670	COG2205	protein histidine kinase activity
CEQ03_RS15675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS15680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS15700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEQ03_RS15720	COG2267	carboxylic ester hydrolase activity
CEQ03_RS15725	COG0156	8-amino-7-oxononanoate synthase activity
CEQ03_RS15730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ03_RS15750	COG1040	competence protein
CEQ03_RS15780	COG2814	Major facilitator Superfamily
CEQ03_RS15785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ03_RS15790	COG1349	DNA-binding transcription factor activity
CEQ03_RS15800	COG1940	carbohydrate kinase activity
CEQ03_RS15805	COG2222	sugar isomerase
CEQ03_RS15810	COG1501	Belongs to the glycosyl hydrolase 31 family
CEQ03_RS15820	COG0673	inositol 2-dehydrogenase activity
CEQ03_RS15845	COG2031	fatty acid transporter
CEQ03_RS15895	COG1104	cysteine desulfurase activity
CEQ03_RS15900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ03_RS15915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ03_RS15920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEQ03_RS15930	COG1845	cytochrome c oxidase, subunit III
CEQ03_RS15935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEQ03_RS15940	COG1999	signal sequence binding
CEQ03_RS15970	COG3932	Exopolysaccharide synthesis, ExoD
CEQ03_RS15975	COG0561	phosphatase activity
CEQ03_RS15995	COG0606	chelatase, subunit chli
CEQ03_RS16035	COG2963	transposase activity
CEQ03_RS16050	COG5642	Protein of unknown function (DUF2384)
CEQ03_RS16120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEQ03_RS16130	COG0602	queuosine metabolic process
CEQ03_RS16170	COG0606	chelatase, subunit chli
CEQ03_RS16230	COG2960	long-chain fatty acid transporting porin activity
CEQ03_RS16240	COG3415	Transposase
CEQ03_RS16240	COG2801	Transposase and inactivated derivatives
CEQ03_RS16255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CEQ03_RS16260	COG1166	arginine decarboxylase activity
CEQ03_RS16300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ03_RS16315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEQ03_RS16315	COG3264	Mechanosensitive ion channel
CEQ03_RS16320	COG1368	sulfuric ester hydrolase activity
CEQ03_RS16325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEQ03_RS16330	COG2354	Protein conserved in bacteria
CEQ03_RS16345	COG2378	regulation of single-species biofilm formation
CEQ03_RS16375	COG3483	tryptophan 2,3-dioxygenase activity
CEQ03_RS16380	COG3104	oligopeptide transport
CEQ03_RS16395	COG4804	nuclease activity
CEQ03_RS16410	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEQ03_RS16425	COG0530	calcium, potassium:sodium antiporter activity
CEQ03_RS16430	COG1320	monovalent cation:proton antiporter activity
CEQ03_RS16435	COG2212	antiporter activity
CEQ03_RS16440	COG1863	multisubunit Na H antiporter MnhE subunit
CEQ03_RS16445	COG0651	ATP synthesis coupled electron transport
CEQ03_RS16450	COG1006	Multisubunit Na H antiporter MnhC subunit
CEQ03_RS16455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEQ03_RS16455	COG2111	Na H antiporter
CEQ03_RS16465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEQ03_RS16470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEQ03_RS16485	COG1597	lipid kinase activity
CEQ03_RS16505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ03_RS16510	COG0134	indole-3-glycerol-phosphate synthase activity
CEQ03_RS16520	COG0730	response to heat
CEQ03_RS16525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ03_RS16530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CEQ03_RS16540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CEQ03_RS16545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEQ03_RS16550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEQ03_RS16565	COG1051	belongs to the nudix hydrolase family
CEQ03_RS16605	COG0316	Belongs to the HesB IscA family
CEQ03_RS16635	COG2814	Major facilitator Superfamily
CEQ03_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS16645	COG1289	transmembrane transporter activity
CEQ03_RS16650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS16655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS16665	COG1473	amidohydrolase
CEQ03_RS16675	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEQ03_RS16675	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEQ03_RS16680	COG1652	LysM domain
CEQ03_RS16715	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CEQ03_RS16725	COG3706	GGDEF domain
CEQ03_RS16730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEQ03_RS16735	COG3118	belongs to the thioredoxin family
CEQ03_RS16750	COG2884	Cell division ATP-binding protein ftsE
CEQ03_RS16755	COG2177	Part of the ABC transporter FtsEX involved in
CEQ03_RS16760	COG2201	protein-glutamate methylesterase activity
CEQ03_RS16765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ03_RS16770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ03_RS16785	COG0151	Belongs to the GarS family
CEQ03_RS16790	COG0138	bifunctional purine biosynthesis protein purh
CEQ03_RS16795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ03_RS16800	COG2267	carboxylic ester hydrolase activity
CEQ03_RS16805	COG2453	phosphatase
CEQ03_RS16805	COG0671	phosphoesterase, PA-phosphatase related
CEQ03_RS16815	COG0204	Acyl-transferase
CEQ03_RS16820	COG4589	Belongs to the CDS family
CEQ03_RS16825	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEQ03_RS16835	COG2264	protein methyltransferase activity
CEQ03_RS16850	COG0439	Biotin carboxylase
CEQ03_RS16855	COG0511	ligase activity, forming carbon-carbon bonds
CEQ03_RS16860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEQ03_RS16870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEQ03_RS16880	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ03_RS16890	COG1686	Belongs to the peptidase S11 family
CEQ03_RS16895	COG1785	Belongs to the alkaline phosphatase family
CEQ03_RS16905	COG0583	DNA-binding transcription factor activity
CEQ03_RS16925	COG4585	Histidine kinase
CEQ03_RS16945	COG0840	transmembrane signaling receptor activity
CEQ03_RS16955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ03_RS16965	COG1324	tolerance protein
CEQ03_RS16970	COG2356	endonuclease I
CEQ03_RS16975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEQ03_RS16980	COG0459	protein refolding
CEQ03_RS17010	COG1846	Transcriptional regulator
CEQ03_RS17030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ03_RS17040	COG2860	membrane
CEQ03_RS17060	COG1252	NADH dehydrogenase
CEQ03_RS17070	COG0625	glutathione transferase activity
CEQ03_RS17075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ03_RS17090	COG0534	Mate efflux family protein
CEQ03_RS17095	COG0616	signal peptide processing
CEQ03_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS17120	COG0009	L-threonylcarbamoyladenylate synthase
CEQ03_RS17125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ03_RS17125	COG1754	DNA topoisomerase type I activity
CEQ03_RS17130	COG1714	RDD family
CEQ03_RS17140	COG2922	Belongs to the Smg family
CEQ03_RS17145	COG0758	DNA mediated transformation
CEQ03_RS17155	COG0242	peptide deformylase activity
CEQ03_RS17160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ03_RS17165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ03_RS17165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ03_RS17200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ03_RS17210	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ03_RS17215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ03_RS17240	COG2259	Doxx family
CEQ03_RS17255	COG0625	glutathione transferase activity
CEQ03_RS17275	COG4206	TonB-dependent receptor
CEQ03_RS17320	COG0477	Major facilitator Superfamily
CEQ03_RS17340	COG0840	transmembrane signaling receptor activity
CEQ03_RS17350	COG4771	TonB-dependent receptor
CEQ03_RS17370	COG2972	Histidine kinase
CEQ03_RS17370	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS17380	COG0181	hydroxymethylbilane synthase activity
CEQ03_RS17405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEQ03_RS17425	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ03_RS17430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ03_RS17445	COG0356	it plays a direct role in the translocation of protons across the membrane
CEQ03_RS17455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ03_RS17460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ03_RS17465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ03_RS17470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ03_RS17475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ03_RS17480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ03_RS17490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ03_RS17500	COG4191	Histidine kinase
CEQ03_RS17505	COG2204	response regulator
CEQ03_RS17515	COG0577	efflux transmembrane transporter activity
CEQ03_RS17520	COG0577	efflux transmembrane transporter activity
CEQ03_RS17520	COG1136	(ABC) transporter
CEQ03_RS17525	COG1136	(ABC) transporter
CEQ03_RS17535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ03_RS17555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ03_RS17565	COG0339	signal peptide processing
CEQ03_RS17580	COG1666	GTP binding
CEQ03_RS17585	COG0697	spore germination
CEQ03_RS17610	COG1505	serine-type exopeptidase activity
CEQ03_RS17615	COG0436	Aminotransferase
CEQ03_RS17625	COG2832	Protein of unknown function (DUF454)
CEQ03_RS17635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEQ03_RS17650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEQ03_RS17660	COG0673	inositol 2-dehydrogenase activity
CEQ03_RS17675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS17705	COG2226	methyltransferase
CEQ03_RS17710	COG0308	aminopeptidase N
CEQ03_RS17725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ03_RS17730	COG1077	Cell shape determining protein MreB Mrl
CEQ03_RS17735	COG1792	Involved in formation and maintenance of cell shape
CEQ03_RS17750	COG0772	Belongs to the SEDS family
CEQ03_RS17755	COG0772	Belongs to the SEDS family
CEQ03_RS17765	COG2951	lytic endotransglycosylase activity
CEQ03_RS17770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEQ03_RS17775	COG1686	Belongs to the peptidase S11 family
CEQ03_RS17785	COG2921	Belongs to the UPF0250 family
CEQ03_RS17795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEQ03_RS17815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CEQ03_RS17820	COG0673	inositol 2-dehydrogenase activity
CEQ03_RS17825	COG2823	Periplasmic or secreted lipoprotein
CEQ03_RS17830	COG4251	negative regulation of phosphorylation
CEQ03_RS17835	COG0784	Response regulator, receiver
CEQ03_RS17840	COG4191	Histidine kinase
CEQ03_RS17850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ03_RS17870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CEQ03_RS17880	COG0837	glucose binding
CEQ03_RS17890	COG1609	Transcriptional regulator
CEQ03_RS17895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ03_RS17900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ03_RS17910	COG3468	outer membrane autotransporter barrel domain protein
CEQ03_RS17950	COG0617	tRNA 3'-terminal CCA addition
CEQ03_RS17975	COG4773	Receptor
CEQ03_RS17985	COG1522	sequence-specific DNA binding
CEQ03_RS18000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ03_RS18005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ03_RS18015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEQ03_RS18020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEQ03_RS18040	COG1064	alcohol dehydrogenase
CEQ03_RS18045	COG0583	DNA-binding transcription factor activity
CEQ03_RS18070	COG1902	pentaerythritol trinitrate reductase activity
CEQ03_RS18085	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CEQ03_RS18095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEQ03_RS18100	COG2203	Gaf domain
CEQ03_RS18100	COG3706	GGDEF domain
CEQ03_RS18100	COG4251	negative regulation of phosphorylation
CEQ03_RS18100	COG5001	Diguanylate cyclase
CEQ03_RS18145	COG1307	EDD domain protein, DegV family
CEQ03_RS18155	COG0804	urea catabolic process
CEQ03_RS18160	COG1228	amidohydrolase
CEQ03_RS18175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEQ03_RS18195	COG0436	Aminotransferase
CEQ03_RS18200	COG1162	GTPase activity
CEQ03_RS18220	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS18225	COG2851	Citrate transporter
CEQ03_RS18240	COG0642	Histidine kinase
CEQ03_RS18255	COG4191	Histidine kinase
CEQ03_RS18265	COG1301	dicarboxylic acid transport
CEQ03_RS18305	COG1560	Kdo2-lipid A biosynthetic process
CEQ03_RS18310	COG1519	Transferase
CEQ03_RS18315	COG0531	amino acid
CEQ03_RS18320	COG1538	Outer membrane efflux protein
CEQ03_RS18325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEQ03_RS18335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS18340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS18355	COG0473	3-isopropylmalate dehydrogenase activity
CEQ03_RS18370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ03_RS18375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEQ03_RS18395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEQ03_RS18400	COG0405	Gamma-glutamyltransferase
CEQ03_RS18405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ03_RS18410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEQ03_RS18420	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS18445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEQ03_RS18480	COG2832	Protein of unknown function (DUF454)
CEQ03_RS18490	COG0848	biopolymer transport protein
CEQ03_RS18500	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CEQ03_RS18520	COG0563	adenylate kinase activity
CEQ03_RS18525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ03_RS18535	COG0671	phosphoesterase, PA-phosphatase related
CEQ03_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS18565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ03_RS18570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ03_RS18580	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CEQ03_RS18585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ03_RS18595	COG1773	rubredoxin
CEQ03_RS18600	COG2912	Transglutaminase-like superfamily
CEQ03_RS18610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEQ03_RS18620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ03_RS18640	COG3079	Belongs to the UPF0149 family
CEQ03_RS18645	COG0006	proline dipeptidase activity
CEQ03_RS18665	COG2974	May be involved in recombination
CEQ03_RS18795	COG4373	Mu-like prophage FluMu protein gp28
CEQ03_RS18930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ03_RS18940	COG0346	lactoylglutathione lyase activity
CEQ03_RS18945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEQ03_RS18950	COG1561	YicC-like family, N-terminal region
CEQ03_RS18955	COG0709	Synthesizes selenophosphate from selenide and ATP
CEQ03_RS18965	COG3276	selenocysteine insertion sequence binding
CEQ03_RS18970	COG1921	L-seryl-tRNASec selenium transferase activity
CEQ03_RS18980	COG2864	formate dehydrogenase
CEQ03_RS18985	COG0437	4 iron, 4 sulfur cluster binding
CEQ03_RS18990	COG0243	molybdopterin cofactor binding
CEQ03_RS18990	COG3383	formate dehydrogenase (NAD+) activity
CEQ03_RS18995	COG3383	formate dehydrogenase (NAD+) activity
CEQ03_RS18995	COG0243	molybdopterin cofactor binding
CEQ03_RS19005	COG1758	RNA polymerase activity
CEQ03_RS19010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ03_RS19020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEQ03_RS19030	COG0254	rRNA binding
CEQ03_RS19080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEQ03_RS19110	COG0714	Associated with various cellular activities
CEQ03_RS19140	COG1301	dicarboxylic acid transport
CEQ03_RS19145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ03_RS19190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ03_RS19215	COG0126	phosphoglycerate kinase activity
CEQ03_RS19225	COG0469	pyruvate kinase activity
CEQ03_RS19230	COG3588	fructose-bisphosphate aldolase
CEQ03_RS19240	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CEQ03_RS19265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ03_RS19270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS19280	COG1115	amino acid carrier protein
CEQ03_RS19285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ03_RS19295	COG1970	mechanosensitive ion channel activity
CEQ03_RS19315	COG3273	potassium ion transport
CEQ03_RS19315	COG0471	metal ion transport
CEQ03_RS19320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEQ03_RS19325	COG2022	thiamine diphosphate biosynthetic process
CEQ03_RS19365	COG0189	ligase activity
CEQ03_RS19380	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS19400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEQ03_RS19435	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ03_RS19445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ03_RS19445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEQ03_RS19455	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ03_RS19460	COG0564	pseudouridine synthase activity
CEQ03_RS19475	COG3011	Protein conserved in bacteria
CEQ03_RS19480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CEQ03_RS19485	COG3387	PFAM Glycoside hydrolase 15-related
CEQ03_RS19510	COG0028	Belongs to the TPP enzyme family
CEQ03_RS19530	COG0542	response to heat
CEQ03_RS19540	COG2205	protein histidine kinase activity
CEQ03_RS19545	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS19555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ03_RS19555	COG4651	solute:proton antiporter activity
CEQ03_RS19565	COG0488	(ABC) transporter
CEQ03_RS19595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ03_RS19615	COG0217	transcriptional regulatory protein
CEQ03_RS19620	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEQ03_RS19625	COG0632	four-way junction helicase activity
CEQ03_RS19640	COG2255	four-way junction helicase activity
CEQ03_RS19645	COG0824	Thioesterase
CEQ03_RS19650	COG0811	peptide transport
CEQ03_RS19665	COG0823	Involved in the tonB-independent uptake of proteins
CEQ03_RS19670	COG2885	chlorophyll binding
CEQ03_RS19685	COG0602	queuosine metabolic process
CEQ03_RS19690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEQ03_RS19845	COG0305	Participates in initiation and elongation during chromosome replication
CEQ03_RS19910	COG1783	phage Terminase large subunit
CEQ03_RS20060	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ03_RS20065	COG0783	Belongs to the Dps family
CEQ03_RS20070	COG1643	Atp-dependent helicase
CEQ03_RS20080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ03_RS20095	COG1215	transferase activity, transferring glycosyl groups
CEQ03_RS20100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ03_RS20110	COG1199	ATP-dependent helicase activity
CEQ03_RS20115	COG1214	PFAM Peptidase M22, glycoprotease
CEQ03_RS20125	COG0189	ligase activity
CEQ03_RS20140	COG0835	chemotaxis
CEQ03_RS20145	COG0840	transmembrane signaling receptor activity
CEQ03_RS20150	COG2198	Histidine kinase
CEQ03_RS20150	COG0643	Histidine kinase
CEQ03_RS20150	COG0784	Response regulator, receiver
CEQ03_RS20165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ03_RS20175	COG0494	nUDIX hydrolase
CEQ03_RS20185	COG3956	TIGRFAM MazG family protein
CEQ03_RS20190	COG1742	UPF0060 membrane protein
CEQ03_RS20200	COG0330	HflC and HflK could
CEQ03_RS20210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEQ03_RS20215	COG0509	glycine decarboxylation via glycine cleavage system
CEQ03_RS20225	COG0583	DNA-binding transcription factor activity
CEQ03_RS20255	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS20265	COG1309	transcriptional regulator
CEQ03_RS20280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ03_RS20285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ03_RS20290	COG0463	Glycosyl transferase, family 2
CEQ03_RS20305	COG1272	protein, Hemolysin III
CEQ03_RS20310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEQ03_RS20320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEQ03_RS20325	COG0626	cystathionine gamma-synthase activity
CEQ03_RS20330	COG0527	aspartate kinase activity
CEQ03_RS20330	COG0460	homoserine dehydrogenase
CEQ03_RS20335	COG2267	carboxylic ester hydrolase activity
CEQ03_RS20340	COG1760	l-serine dehydratase
CEQ03_RS20370	COG0784	Response regulator, receiver
CEQ03_RS20370	COG2198	Histidine kinase
CEQ03_RS20370	COG5002	protein histidine kinase activity
CEQ03_RS20380	COG0477	Major facilitator Superfamily
CEQ03_RS20400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ03_RS20415	COG0259	pyridoxamine-phosphate oxidase activity
CEQ03_RS20435	COG3829	transcription factor binding
CEQ03_RS20455	COG3609	addiction module antidote protein, CC2985 family
CEQ03_RS20465	COG2828	Protein conserved in bacteria
CEQ03_RS20470	COG2079	MmgE PrpD family protein
CEQ03_RS20480	COG2373	Large extracellular alpha-helical protein
CEQ03_RS20485	COG4953	penicillin-binding protein 1C
CEQ03_RS20495	COG0678	peroxiredoxin activity
CEQ03_RS20510	COG0604	alcohol dehydrogenase
CEQ03_RS20515	COG0330	HflC and HflK could
CEQ03_RS20520	COG0330	HflC and HflK could
CEQ03_RS20530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ03_RS20540	COG0739	heme binding
CEQ03_RS20545	COG1376	ErfK ybiS ycfS ynhG family protein
CEQ03_RS20575	COG0753	catalase activity
CEQ03_RS20580	COG2207	Transcriptional regulator
CEQ03_RS20580	COG1917	Cupin 2, conserved barrel domain protein
CEQ03_RS20585	COG1113	amino acid transport
CEQ03_RS20595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ03_RS20595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ03_RS20600	COG2814	Major facilitator Superfamily
CEQ03_RS20655	COG2879	small protein
CEQ03_RS20670	COG1741	Belongs to the pirin family
CEQ03_RS20680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ03_RS20685	COG1741	Belongs to the pirin family
CEQ03_RS20705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ03_RS20710	COG0481	GTPase activity
CEQ03_RS20715	COG0681	Belongs to the peptidase S26 family
CEQ03_RS20730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEQ03_RS20735	COG1381	Involved in DNA repair and RecF pathway recombination
CEQ03_RS20740	COG0745	RESPONSE REGULATOR receiver
CEQ03_RS20745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ03_RS20750	COG2954	triphosphatase activity
CEQ03_RS20755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEQ03_RS20760	COG1472	Belongs to the glycosyl hydrolase 3 family
CEQ03_RS20765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CEQ03_RS20770	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CEQ03_RS20775	COG1278	Cold shock
CEQ03_RS20780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ03_RS20795	COG1201	RNA secondary structure unwinding
CEQ03_RS20800	COG1793	dna ligase
CEQ03_RS20810	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS20825	COG0183	Belongs to the thiolase family
CEQ03_RS20845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ03_RS20855	COG1451	nucleotide metabolic process
CEQ03_RS20860	COG3122	Protein conserved in bacteria
CEQ03_RS20865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEQ03_RS20905	COG0443	Heat shock 70 kDa protein
CEQ03_RS20910	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ03_RS20940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEQ03_RS20940	COG0392	lysyltransferase activity
CEQ03_RS20945	COG0251	oxidation-reduction process
CEQ03_RS20950	COG2878	Part of a membrane complex involved in electron transport
CEQ03_RS20960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ03_RS20960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ03_RS20975	COG0346	lactoylglutathione lyase activity
CEQ03_RS20980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEQ03_RS20990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ03_RS21010	COG4251	negative regulation of phosphorylation
CEQ03_RS21010	COG5001	Diguanylate cyclase
CEQ03_RS21010	COG2203	Gaf domain
CEQ03_RS21010	COG3706	GGDEF domain
CEQ03_RS21020	COG3118	belongs to the thioredoxin family
CEQ03_RS21030	COG0495	leucyl-tRNA aminoacylation
CEQ03_RS21045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ03_RS21055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ03_RS21070	COG4771	TonB-dependent receptor
CEQ03_RS21080	COG2968	Membrane
CEQ03_RS21095	COG0312	modulator of DNA gyrase
CEQ03_RS21100	COG3028	Belongs to the UPF0307 family
CEQ03_RS21105	COG0312	modulator of DNA gyrase
CEQ03_RS21115	COG0142	geranyltranstransferase activity
CEQ03_RS21120	COG1722	exodeoxyribonuclease VII activity
CEQ03_RS21140	COG1301	dicarboxylic acid transport
CEQ03_RS21145	COG0791	NLP P60 protein
CEQ03_RS21150	COG0791	NLP P60 protein
CEQ03_RS21155	COG1047	Peptidyl-prolyl cis-trans
CEQ03_RS21160	COG2311	Membrane
CEQ03_RS21165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ03_RS21175	COG0697	spore germination
CEQ03_RS21210	COG3590	peptidase
CEQ03_RS21220	COG4771	TonB-dependent receptor
CEQ03_RS21225	COG4771	TonB-dependent receptor
CEQ03_RS21230	COG0489	protein tyrosine kinase activity
CEQ03_RS21235	COG0717	Belongs to the dCTP deaminase family
CEQ03_RS21250	COG0412	Dienelactone hydrolase
CEQ03_RS21255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ03_RS21265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ03_RS21270	COG0433	COG0433 Predicted ATPase
CEQ03_RS21285	COG0688	phosphatidylethanolamine metabolic process
CEQ03_RS21290	COG1999	signal sequence binding
CEQ03_RS21295	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ03_RS21300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ03_RS21310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ03_RS21325	COG0101	tRNA pseudouridine synthase activity
CEQ03_RS21330	COG0135	phosphoribosylanthranilate isomerase activity
CEQ03_RS21350	COG0133	tryptophan synthase activity
CEQ03_RS21360	COG0159	tryptophan synthase activity
CEQ03_RS21365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ03_RS21370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ03_RS21380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ03_RS21385	COG0726	polysaccharide deacetylase
CEQ03_RS21390	COG0438	transferase activity, transferring glycosyl groups
CEQ03_RS21395	COG3083	sulfuric ester hydrolase activity
CEQ03_RS21405	COG0149	triose-phosphate isomerase activity
CEQ03_RS21420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEQ03_RS21425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEQ03_RS21430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEQ03_RS21435	COG0649	NAD binding
CEQ03_RS21440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CEQ03_RS21455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CEQ03_RS21460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEQ03_RS21470	COG0713	ATP synthesis coupled electron transport
CEQ03_RS21485	COG1007	ATP synthesis coupled electron transport
CEQ03_RS21500	COG0779	Required for maturation of 30S ribosomal subunits
CEQ03_RS21505	COG0195	Participates in both transcription termination and antitermination
CEQ03_RS21510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEQ03_RS21515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEQ03_RS21525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEQ03_RS21530	COG1185	polyribonucleotide nucleotidyltransferase activity
CEQ03_RS21570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEQ03_RS21575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEQ03_RS21580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEQ03_RS21585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEQ03_RS21590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ03_RS21590	COG0072	phenylalanine-tRNA ligase activity
CEQ03_RS21595	COG0776	regulation of translation
CEQ03_RS21630	COG1794	racemase activity, acting on amino acids and derivatives
CEQ03_RS21635	COG1280	lysine exporter protein (LysE YggA)
CEQ03_RS21640	COG5487	UPF0391 membrane protein
CEQ03_RS21645	COG2076	Multidrug Resistance protein
CEQ03_RS21680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEQ03_RS21690	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS21715	COG2130	NADP-dependent
CEQ03_RS21720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ03_RS21720	COG2169	Transcriptional regulator
CEQ03_RS21750	COG1309	transcriptional regulator
CEQ03_RS21755	COG4771	TonB-dependent receptor
CEQ03_RS21775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEQ03_RS21785	COG1570	exodeoxyribonuclease VII activity
CEQ03_RS21790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ03_RS21795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEQ03_RS21795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEQ03_RS21800	COG0802	atpase or kinase
CEQ03_RS21805	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEQ03_RS21810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEQ03_RS21830	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ03_RS21840	COG0501	Belongs to the peptidase M48B family
CEQ03_RS21865	COG5001	Diguanylate cyclase
CEQ03_RS21865	COG3300	MHYT domain
CEQ03_RS21870	COG1509	lysine 2,3-aminomutase activity
CEQ03_RS21875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ03_RS21880	COG0402	S-adenosylhomocysteine deaminase activity
CEQ03_RS21885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ03_RS21905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEQ03_RS21925	COG2166	iron-sulfur cluster assembly
CEQ03_RS21940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEQ03_RS21945	COG0137	argininosuccinate synthase activity
CEQ03_RS21950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ03_RS21955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ03_RS21965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEQ03_RS21970	COG0165	Argininosuccinate lyase
CEQ03_RS21985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEQ03_RS21995	COG1215	transferase activity, transferring glycosyl groups
CEQ03_RS22000	COG0726	polysaccharide deacetylase
CEQ03_RS22000	COG1649	PFAM Uncharacterised BCR, COG1649
CEQ03_RS22030	COG1294	oxidase, subunit
CEQ03_RS22040	COG4988	ABC transporter
CEQ03_RS22045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEQ03_RS22055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEQ03_RS22065	COG3088	subunit of a heme lyase
CEQ03_RS22065	COG4235	cytochrome complex assembly
CEQ03_RS22080	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEQ03_RS22100	COG4133	protoheme IX ABC transporter activity
CEQ03_RS22105	COG0436	Aminotransferase
CEQ03_RS22125	COG2814	Major facilitator Superfamily
CEQ03_RS22135	COG1187	pseudouridine synthase activity
CEQ03_RS22140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEQ03_RS22145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEQ03_RS22150	COG2350	Protein conserved in bacteria
CEQ03_RS22155	COG0271	Belongs to the BolA IbaG family
CEQ03_RS22185	COG0395	ABC-type sugar transport system, permease component
CEQ03_RS22200	COG1530	ribonuclease E activity
CEQ03_RS22210	COG0428	transporter
CEQ03_RS22220	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEQ03_RS22225	COG0316	Belongs to the HesB IscA family
CEQ03_RS22225	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEQ03_RS22240	COG4290	ribonuclease
CEQ03_RS22245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEQ03_RS22260	COG0705	Rhomboid family
CEQ03_RS22280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ03_RS22290	COG0339	signal peptide processing
CEQ03_RS22295	COG0386	Belongs to the glutathione peroxidase family
CEQ03_RS22310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEQ03_RS22315	COG1595	DNA-templated transcription, initiation
CEQ03_RS22330	COG0625	glutathione transferase activity
CEQ03_RS22365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEQ03_RS22370	COG0084	hydrolase, TatD family'
CEQ03_RS22390	COG0625	glutathione transferase activity
CEQ03_RS22410	COG0305	Participates in initiation and elongation during chromosome replication
CEQ03_RS22420	COG3540	Alkaline phosphatase
CEQ03_RS22445	COG0567	Dehydrogenase, E1 component
CEQ03_RS22455	COG2850	peptidyl-arginine hydroxylation
CEQ03_RS22465	COG0114	fumarate hydratase activity
CEQ03_RS22490	COG1131	(ABC) transporter
CEQ03_RS22495	COG1725	Transcriptional regulator
CEQ03_RS22505	COG0386	Belongs to the glutathione peroxidase family
CEQ03_RS22520	COG2900	Belongs to the SlyX family
CEQ03_RS22540	COG2226	methyltransferase
CEQ03_RS22545	COG1960	acyl-CoA dehydrogenase activity
CEQ03_RS22560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ03_RS22565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family