locus-tag	class	description
EGY09_RS00005	COG0697	spore germination
EGY09_RS00020	COG1136	(ABC) transporter
EGY09_RS00020	COG0577	efflux transmembrane transporter activity
EGY09_RS00030	COG1136	(ABC) transporter
EGY09_RS00050	COG4585	Histidine kinase
EGY09_RS00055	COG2197	response regulator
EGY09_RS00070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGY09_RS00085	COG0628	permease
EGY09_RS00105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGY09_RS00120	COG5507	3-demethylubiquinone-9 3-methyltransferase
EGY09_RS00150	COG2814	Major facilitator Superfamily
EGY09_RS00155	COG0583	DNA-binding transcription factor activity
EGY09_RS00160	COG4807	Protein conserved in bacteria
EGY09_RS00170	COG4221	oxidoreductase activity
EGY09_RS00180	COG0018	arginyl-trna synthetase
EGY09_RS00185	COG2003	Belongs to the UPF0758 family
EGY09_RS00190	COG2197	response regulator
EGY09_RS00195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGY09_RS00215	COG2205	protein histidine kinase activity
EGY09_RS00225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGY09_RS00230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGY09_RS00245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGY09_RS00250	COG0708	Exodeoxyribonuclease III
EGY09_RS00255	COG2223	nitrite transmembrane transporter activity
EGY09_RS00270	COG0739	heme binding
EGY09_RS00275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGY09_RS00335	COG2234	aminopeptidase activity
EGY09_RS00345	COG4942	peptidase
EGY09_RS00350	COG0793	Belongs to the peptidase S41A family
EGY09_RS00360	COG2067	long-chain fatty acid transport protein
EGY09_RS00385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGY09_RS00430	COG0109	protoheme IX farnesyltransferase activity
EGY09_RS00450	COG0358	DNA primase activity
EGY09_RS00455	COG1295	ribonuclease BN
EGY09_RS00470	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGY09_RS00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGY09_RS00485	COG0668	transmembrane transport
EGY09_RS00500	COG2133	pyrroloquinoline quinone binding
EGY09_RS00505	COG4682	membrane
EGY09_RS00515	COG0531	amino acid
EGY09_RS00525	COG1737	Transcriptional regulator
EGY09_RS00530	COG4948	Mandelate Racemase Muconate Lactonizing
EGY09_RS00580	COG5383	Protein conserved in bacteria
EGY09_RS00590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGY09_RS00595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGY09_RS00625	COG0778	Nitroreductase
EGY09_RS00630	COG2353	YceI-like domain
EGY09_RS00645	COG2375	cellular response to nickel ion
EGY09_RS00760	COG2267	carboxylic ester hydrolase activity
EGY09_RS00820	COG0488	(ABC) transporter
EGY09_RS00825	COG0583	DNA-binding transcription factor activity
EGY09_RS00835	COG2814	Major facilitator Superfamily
EGY09_RS00840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGY09_RS00845	COG1113	amino acid transport
EGY09_RS00850	COG0741	lytic transglycosylase activity
EGY09_RS00875	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EGY09_RS00885	COG5507	3-demethylubiquinone-9 3-methyltransferase
EGY09_RS00890	COG4941	Belongs to the sigma-70 factor family
EGY09_RS00920	COG3275	phosphorelay sensor kinase activity
EGY09_RS00925	COG3279	Response regulator of the LytR AlgR family
EGY09_RS00945	COG1309	transcriptional regulator
EGY09_RS00955	COG2814	Major facilitator Superfamily
EGY09_RS00960	COG3590	peptidase
EGY09_RS00965	COG5001	Diguanylate cyclase
EGY09_RS00970	COG0583	DNA-binding transcription factor activity
EGY09_RS00980	COG3384	dioxygenase
EGY09_RS00985	COG0025	NhaP-type Na H and K H
EGY09_RS01010	COG1360	Flagellar Motor Protein
EGY09_RS01040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY09_RS01055	COG5002	protein histidine kinase activity
EGY09_RS01070	COG2813	Specifically methylates the guanine in position
EGY09_RS01075	COG1187	pseudouridine synthase activity
EGY09_RS01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGY09_RS01090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGY09_RS01095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGY09_RS01110	COG0583	DNA-binding transcription factor activity
EGY09_RS01115	COG2226	methyltransferase
EGY09_RS01140	COG1956	GAF domain-containing protein
EGY09_RS01145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGY09_RS01150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY09_RS01155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY09_RS01160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY09_RS01160	COG0785	Cytochrome C biogenesis protein
EGY09_RS01165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY09_RS01170	COG0745	RESPONSE REGULATOR receiver
EGY09_RS01175	COG2205	protein histidine kinase activity
EGY09_RS01180	COG2205	protein histidine kinase activity
EGY09_RS01185	COG0745	RESPONSE REGULATOR receiver
EGY09_RS01190	COG0367	asparagine synthase
EGY09_RS01200	COG0720	synthase
EGY09_RS01215	COG0513	Belongs to the DEAD box helicase family
EGY09_RS01225	COG0625	glutathione transferase activity
EGY09_RS01230	COG1573	uracil-dna glycosylase
EGY09_RS01265	COG0626	cystathionine gamma-synthase activity
EGY09_RS01295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGY09_RS01315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGY09_RS01320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGY09_RS01345	COG0463	Glycosyl transferase, family 2
EGY09_RS01350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGY09_RS01360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGY09_RS01395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGY09_RS01425	COG1127	ABC transporter
EGY09_RS01430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGY09_RS01445	COG0442	prolyl-tRNA aminoacylation
EGY09_RS01465	COG1183	phosphatidylcholine synthase activity
EGY09_RS01475	COG0456	acetyltransferase
EGY09_RS01485	COG0525	valine-tRNA ligase activity
EGY09_RS01495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGY09_RS01505	COG0795	lipopolysaccharide-transporting ATPase activity
EGY09_RS01515	COG4974	Belongs to the 'phage' integrase family
EGY09_RS01520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGY09_RS01530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGY09_RS01530	COG0047	phosphoribosylformylglycinamidine synthase activity
EGY09_RS01535	COG5295	Hep Hag repeat protein
EGY09_RS01540	COG1404	Belongs to the peptidase S8 family
EGY09_RS01545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGY09_RS01550	COG1459	type II secretion system
EGY09_RS01555	COG2165	general secretion pathway protein
EGY09_RS01560	COG4970	Tfp pilus assembly protein FimT
EGY09_RS01565	COG2165	general secretion pathway protein
EGY09_RS01570	COG4795	General secretion pathway protein
EGY09_RS01575	COG3156	type II secretion system protein K
EGY09_RS01580	COG3166	PFAM Fimbrial assembly family protein
EGY09_RS01595	COG1450	Type ii and iii secretion system protein
EGY09_RS01625	COG3539	Fimbrial protein
EGY09_RS01655	COG2194	sulfuric ester hydrolase activity
EGY09_RS01670	COG1215	transferase activity, transferring glycosyl groups
EGY09_RS01680	COG0457	Tetratricopeptide repeat
EGY09_RS01680	COG3118	belongs to the thioredoxin family
EGY09_RS01685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGY09_RS01690	COG2252	PERMEase
EGY09_RS01700	COG0488	(ABC) transporter
EGY09_RS01710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGY09_RS01730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGY09_RS01735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGY09_RS01735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGY09_RS01790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGY09_RS01795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGY09_RS01805	COG3152	Membrane
EGY09_RS01815	COG3121	Chaperone
EGY09_RS01825	COG3188	usher protein
EGY09_RS01855	COG2755	lipolytic protein G-D-S-L family
EGY09_RS01855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGY09_RS01860	COG0277	FAD linked oxidase domain protein
EGY09_RS01865	COG1988	membrane-bound metal-dependent
EGY09_RS01900	COG2001	Belongs to the MraZ family
EGY09_RS01905	COG0275	rRNA processing
EGY09_RS01910	COG3116	cell division
EGY09_RS01925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGY09_RS01945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGY09_RS01950	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGY09_RS01955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGY09_RS01965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGY09_RS01970	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EGY09_RS01980	COG0739	heme binding
EGY09_RS01985	COG0653	protein targeting
EGY09_RS01990	COG0494	nUDIX hydrolase
EGY09_RS02000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGY09_RS02005	COG2267	carboxylic ester hydrolase activity
EGY09_RS02010	COG3275	phosphorelay sensor kinase activity
EGY09_RS02015	COG3279	Response regulator of the LytR AlgR family
EGY09_RS02020	COG0402	S-adenosylhomocysteine deaminase activity
EGY09_RS02035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGY09_RS02040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGY09_RS02050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EGY09_RS02055	COG1607	acyl-coa hydrolase
EGY09_RS02060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGY09_RS02080	COG4106	trans-aconitate 2-methyltransferase activity
EGY09_RS02085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGY09_RS02105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY09_RS02110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGY09_RS02115	COG0667	Aldo Keto reductase
EGY09_RS02125	COG4771	TonB-dependent receptor
EGY09_RS02140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGY09_RS02145	COG4181	ATPase activity
EGY09_RS02160	COG0642	Histidine kinase
EGY09_RS02175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGY09_RS02180	COG0861	Integral membrane protein TerC family
EGY09_RS02185	COG2814	Major facilitator Superfamily
EGY09_RS02190	COG1704	LemA family
EGY09_RS02205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGY09_RS02210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGY09_RS02220	COG3738	Protein conserved in bacteria
EGY09_RS02225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGY09_RS02230	COG2967	ApaG domain
EGY09_RS02235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGY09_RS02240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGY09_RS02245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGY09_RS02250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGY09_RS02260	COG2096	Adenosyltransferase
EGY09_RS02270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGY09_RS02275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGY09_RS02280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGY09_RS02285	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EGY09_RS02310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGY09_RS02320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY09_RS02330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGY09_RS02335	COG0583	DNA-binding transcription factor activity
EGY09_RS02340	COG3634	alkyl hydroperoxide reductase activity
EGY09_RS02380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGY09_RS02380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGY09_RS02395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGY09_RS02420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGY09_RS02435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGY09_RS02455	COG1404	Belongs to the peptidase S8 family
EGY09_RS02475	COG1295	ribonuclease BN
EGY09_RS02480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY09_RS02500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGY09_RS02505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGY09_RS02520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGY09_RS02530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGY09_RS02535	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGY09_RS02540	COG0193	aminoacyl-tRNA hydrolase activity
EGY09_RS02545	COG0012	GTP binding
EGY09_RS02550	COG4206	TonB-dependent receptor
EGY09_RS02555	COG4242	Belongs to the peptidase S51 family
EGY09_RS02580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGY09_RS02595	COG0250	Participates in transcription elongation, termination and antitermination
EGY09_RS02600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGY09_RS02605	COG0081	regulation of translation
EGY09_RS02615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGY09_RS02620	COG0222	ribosome binding
EGY09_RS02625	COG0085	RNA polymerase activity
EGY09_RS02630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGY09_RS02635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGY09_RS02640	COG0049	tRNA binding
EGY09_RS02645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGY09_RS02650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGY09_RS02655	COG0051	transcription antitermination factor activity, RNA binding
EGY09_RS02660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGY09_RS02665	COG0088	Forms part of the polypeptide exit tunnel
EGY09_RS02670	COG0089	rRNA binding
EGY09_RS02675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGY09_RS02680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGY09_RS02685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGY09_RS02690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGY09_RS02695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGY09_RS02700	COG0255	Belongs to the universal ribosomal protein uL29 family
EGY09_RS02705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGY09_RS02710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGY09_RS02715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGY09_RS02720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGY09_RS02725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGY09_RS02735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGY09_RS02740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGY09_RS02745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGY09_RS02750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGY09_RS02755	COG1841	ribosomal large subunit assembly
EGY09_RS02760	COG0200	Binds to the 23S rRNA
EGY09_RS02765	COG0201	protein transport
EGY09_RS02770	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGY09_RS02775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EGY09_RS02780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGY09_RS02785	COG0202	RNA polymerase activity
EGY09_RS02790	COG0203	ribosomal protein L17
EGY09_RS02805	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EGY09_RS02820	COG0154	amidase activity
EGY09_RS02835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGY09_RS02840	COG0039	L-malate dehydrogenase activity
EGY09_RS02845	COG0564	pseudouridine synthase activity
EGY09_RS02855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGY09_RS02870	COG0625	glutathione transferase activity
EGY09_RS02880	COG1902	pentaerythritol trinitrate reductase activity
EGY09_RS02880	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGY09_RS02885	COG2364	Membrane
EGY09_RS02890	COG0604	alcohol dehydrogenase
EGY09_RS02905	COG1187	pseudouridine synthase activity
EGY09_RS02925	COG1063	alcohol dehydrogenase
EGY09_RS02935	COG0406	alpha-ribazole phosphatase activity
EGY09_RS02940	COG0285	dihydrofolate synthase activity
EGY09_RS02960	COG2833	Protein of unknown function (DUF455)
EGY09_RS02970	COG3291	Pkd domain containing protein
EGY09_RS02975	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY09_RS02985	COG0438	transferase activity, transferring glycosyl groups
EGY09_RS02995	COG0248	Ppx GppA phosphatase
EGY09_RS03000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGY09_RS03015	COG4783	chaperone-mediated protein folding
EGY09_RS03030	COG0473	3-isopropylmalate dehydrogenase activity
EGY09_RS03095	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGY09_RS03100	COG0740	serine-type endopeptidase activity
EGY09_RS03105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGY09_RS03145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGY09_RS03150	COG1388	LysM domain
EGY09_RS03150	COG3942	CHAP domain
EGY09_RS03155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY09_RS03165	COG0328	RNA-DNA hybrid ribonuclease activity
EGY09_RS03170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGY09_RS03175	COG0631	protein serine/threonine phosphatase activity
EGY09_RS03195	COG0859	PFAM glycosyl transferase family 9
EGY09_RS03200	COG3642	lipopolysaccharide core region biosynthetic process
EGY09_RS03205	COG1234	tRNA 3'-trailer cleavage
EGY09_RS03220	COG2076	Multidrug Resistance protein
EGY09_RS03250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGY09_RS03260	COG0537	adenosine 5'-monophosphoramidase activity
EGY09_RS03280	COG0714	Associated with various cellular activities
EGY09_RS03295	COG1399	metal-binding, possibly nucleic acid-binding protein
EGY09_RS03300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGY09_RS03305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY09_RS03315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGY09_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS03330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY09_RS03335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGY09_RS03340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGY09_RS03345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGY09_RS03500	COG4774	siderophore transport
EGY09_RS03515	COG2223	nitrite transmembrane transporter activity
EGY09_RS03540	COG0583	DNA-binding transcription factor activity
EGY09_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY09_RS03550	COG0697	spore germination
EGY09_RS03555	COG0583	DNA-binding transcription factor activity
EGY09_RS03560	COG0477	Major facilitator Superfamily
EGY09_RS03595	COG0583	DNA-binding transcription factor activity
EGY09_RS03605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGY09_RS03620	COG0667	Aldo Keto reductase
EGY09_RS03640	COG2818	Glycosylase
EGY09_RS03645	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EGY09_RS03650	COG1678	Uncharacterized ACR, COG1678
EGY09_RS03655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGY09_RS03660	COG0540	Belongs to the ATCase OTCase family
EGY09_RS03680	COG2239	Acts as a magnesium transporter
EGY09_RS03685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGY09_RS03700	COG1660	Displays ATPase and GTPase activities
EGY09_RS03705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EGY09_RS03710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGY09_RS03715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGY09_RS03725	COG1137	ATPase activity
EGY09_RS03740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGY09_RS03755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGY09_RS03775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGY09_RS03795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGY09_RS03805	COG0628	permease
EGY09_RS03820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGY09_RS03825	COG3178	'Phosphotransferase
EGY09_RS03830	COG2261	transglycosylase associated protein
EGY09_RS03840	COG1555	photosystem II stabilization
EGY09_RS03860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGY09_RS03865	COG1477	protein flavinylation
EGY09_RS03885	COG4771	TonB-dependent receptor
EGY09_RS03895	COG3128	pkhd-type hydroxylase
EGY09_RS03905	COG4774	siderophore transport
EGY09_RS03915	COG2146	nitrite reductase [NAD(P)H] activity
EGY09_RS03930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGY09_RS03935	COG0719	Fe-S assembly protein
EGY09_RS03940	COG0396	ATPase activity
EGY09_RS03950	COG0719	Fe-S assembly protein
EGY09_RS03955	COG1959	2 iron, 2 sulfur cluster binding
EGY09_RS03965	COG0693	protein deglycase activity
EGY09_RS03990	COG1764	response to oxidative stress
EGY09_RS03995	COG0384	phenazine biosynthesis protein PhzF
EGY09_RS04000	COG0384	phenazine biosynthesis protein PhzF
EGY09_RS04005	COG0527	aspartate kinase activity
EGY09_RS04030	COG0142	geranyltranstransferase activity
EGY09_RS04035	COG0366	Alpha amylase catalytic
EGY09_RS04045	COG1082	Xylose isomerase domain protein TIM barrel
EGY09_RS04055	COG2190	(PTS) system
EGY09_RS04055	COG2211	Major facilitator Superfamily
EGY09_RS04085	COG1131	(ABC) transporter
EGY09_RS04095	COG0629	single-stranded DNA binding
EGY09_RS04130	COG0673	inositol 2-dehydrogenase activity
EGY09_RS04135	COG2211	Major facilitator Superfamily
EGY09_RS04145	COG1609	Transcriptional regulator
EGY09_RS04185	COG0640	Transcriptional regulator
EGY09_RS04200	COG3655	Transcriptional regulator
EGY09_RS04205	COG1253	flavin adenine dinucleotide binding
EGY09_RS04210	COG1408	metallophosphoesterase
EGY09_RS04215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EGY09_RS04235	COG2259	Doxx family
EGY09_RS04265	COG0477	Major facilitator Superfamily
EGY09_RS04280	COG1802	Transcriptional regulator
EGY09_RS04315	COG3052	prosthetic group binding
EGY09_RS04330	COG0579	oxidoreductase
EGY09_RS04360	COG3104	oligopeptide transport
EGY09_RS04375	COG1297	OPT oligopeptide transporter protein
EGY09_RS04380	COG0823	Involved in the tonB-independent uptake of proteins
EGY09_RS04380	COG1506	peptidase
EGY09_RS04395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGY09_RS04400	COG2894	cell division
EGY09_RS04415	COG4585	Histidine kinase
EGY09_RS04420	COG2197	response regulator
EGY09_RS04460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EGY09_RS04470	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EGY09_RS04480	COG1595	DNA-templated transcription, initiation
EGY09_RS04490	COG1946	Acyl-CoA thioesterase
EGY09_RS04510	COG0824	Thioesterase
EGY09_RS04515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGY09_RS04520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGY09_RS04525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGY09_RS04530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGY09_RS04535	COG0268	Binds directly to 16S ribosomal RNA
EGY09_RS04540	COG0728	peptidoglycan biosynthetic process
EGY09_RS04545	COG0196	riboflavin kinase activity
EGY09_RS04550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGY09_RS04560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EGY09_RS04600	COG4206	TonB-dependent receptor
EGY09_RS04620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY09_RS04645	COG3209	COG3209 Rhs family protein
EGY09_RS04690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGY09_RS04695	COG1845	cytochrome c oxidase, subunit III
EGY09_RS04700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGY09_RS04715	COG0326	Molecular chaperone. Has ATPase activity
EGY09_RS04735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGY09_RS04750	COG0228	four-way junction DNA binding
EGY09_RS04755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGY09_RS04760	COG0336	Belongs to the RNA methyltransferase TrmD family
EGY09_RS04765	COG0335	large ribosomal subunit rRNA binding
EGY09_RS04785	COG0534	Mate efflux family protein
EGY09_RS04805	COG0753	catalase activity
EGY09_RS04830	COG0840	transmembrane signaling receptor activity
EGY09_RS04850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS04870	COG4771	TonB-dependent receptor
EGY09_RS04875	COG0739	heme binding
EGY09_RS04885	COG0024	Methionine aminopeptidase
EGY09_RS04910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGY09_RS04935	COG1647	Serine aminopeptidase, S33
EGY09_RS04960	COG2814	Major facilitator Superfamily
EGY09_RS04965	COG3706	GGDEF domain
EGY09_RS04990	COG0588	phosphoglycerate mutase activity
EGY09_RS04995	COG3590	peptidase
EGY09_RS05005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGY09_RS05015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGY09_RS05020	COG0745	RESPONSE REGULATOR receiver
EGY09_RS05025	COG2205	protein histidine kinase activity
EGY09_RS05030	COG4452	Inner membrane protein CreD
EGY09_RS05045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGY09_RS05050	COG0735	belongs to the Fur family
EGY09_RS05090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGY09_RS05135	COG5002	protein histidine kinase activity
EGY09_RS05135	COG5001	Diguanylate cyclase
EGY09_RS05145	COG1187	pseudouridine synthase activity
EGY09_RS05155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGY09_RS05175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY09_RS05180	COG1132	(ABC) transporter
EGY09_RS05230	COG1695	Transcriptional regulator
EGY09_RS05250	COG1981	membrane
EGY09_RS05255	COG0825	malonyl-CoA metabolic process
EGY09_RS05280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY09_RS05290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY09_RS05295	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGY09_RS05300	COG0750	zinc metalloprotease
EGY09_RS05305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGY09_RS05310	COG0575	Belongs to the CDS family
EGY09_RS05315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGY09_RS05320	COG0233	cytoplasmic translational termination
EGY09_RS05325	COG0528	UMP kinase activity
EGY09_RS05335	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGY09_RS05340	COG0052	Belongs to the universal ribosomal protein uS2 family
EGY09_RS05360	COG3188	usher protein
EGY09_RS05380	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGY09_RS05395	COG1393	Belongs to the ArsC family
EGY09_RS05400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGY09_RS05405	COG0367	asparagine synthase
EGY09_RS05410	COG0475	glutathione-regulated potassium exporter activity
EGY09_RS05445	COG1566	PFAM secretion protein HlyD family protein
EGY09_RS05450	COG2814	Major facilitator Superfamily
EGY09_RS05460	COG0583	DNA-binding transcription factor activity
EGY09_RS05480	COG0557	exoribonuclease II activity
EGY09_RS05490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY09_RS05495	COG1538	Outer membrane efflux protein
EGY09_RS05500	COG1136	(ABC) transporter
EGY09_RS05500	COG0577	efflux transmembrane transporter activity
EGY09_RS05505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS05525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGY09_RS05530	COG2259	Doxx family
EGY09_RS05540	COG3220	belongs to the UPF0276 family
EGY09_RS05550	COG0704	Plays a role in the regulation of phosphate uptake
EGY09_RS05560	COG0581	inorganic phosphate transmembrane transporter activity
EGY09_RS05565	COG0573	inorganic phosphate transmembrane transporter activity
EGY09_RS05570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGY09_RS05575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGY09_RS05585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGY09_RS05595	COG1024	Enoyl-CoA hydratase
EGY09_RS05605	COG0494	nUDIX hydrolase
EGY09_RS05625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGY09_RS05625	COG0116	Belongs to the methyltransferase superfamily
EGY09_RS05645	COG2733	membrane
EGY09_RS05655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGY09_RS05660	COG1012	belongs to the aldehyde dehydrogenase family
EGY09_RS05670	COG0477	Major facilitator Superfamily
EGY09_RS05675	COG2703	oxygen carrier activity
EGY09_RS05695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY09_RS05700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EGY09_RS05705	COG0174	glutamine synthetase
EGY09_RS05715	COG2072	flavoprotein involved in K transport
EGY09_RS05720	COG3842	ATPase activity
EGY09_RS05725	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGY09_RS05730	COG1177	transmembrane transport
EGY09_RS05735	COG1012	belongs to the aldehyde dehydrogenase family
EGY09_RS05750	COG4535	Mg2 and Co2 transporter CorC
EGY09_RS05770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGY09_RS05775	COG1702	phosphate starvation-inducible protein PhoH
EGY09_RS05780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS05785	COG1131	(ABC) transporter
EGY09_RS05790	COG0842	Transport permease protein
EGY09_RS05795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGY09_RS05810	COG0741	lytic transglycosylase activity
EGY09_RS05815	COG0723	plastoquinol--plastocyanin reductase activity
EGY09_RS05820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EGY09_RS05825	COG2857	Cytochrome c1
EGY09_RS05830	COG0625	glutathione transferase activity
EGY09_RS05835	COG2969	positive regulation of protein catabolic process
EGY09_RS05870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGY09_RS05880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGY09_RS05895	COG1611	Belongs to the LOG family
EGY09_RS05940	COG0556	nucleotide-excision repair
EGY09_RS05975	COG3713	MltA-interacting MipA family protein
EGY09_RS05995	COG0811	peptide transport
EGY09_RS06010	COG1663	tetraacyldisaccharide 4'-kinase activity
EGY09_RS06015	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EGY09_RS06020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGY09_RS06030	COG0322	excinuclease ABC activity
EGY09_RS06065	COG1136	(ABC) transporter
EGY09_RS06065	COG0577	efflux transmembrane transporter activity
EGY09_RS06125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGY09_RS06160	COG0583	DNA-binding transcription factor activity
EGY09_RS06180	COG4977	sequence-specific DNA binding
EGY09_RS06180	COG1917	Cupin 2, conserved barrel domain protein
EGY09_RS06185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGY09_RS06205	COG0348	domain, Protein
EGY09_RS06220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGY09_RS06235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGY09_RS06240	COG0069	glutamate synthase activity
EGY09_RS06265	COG1054	Belongs to the UPF0176 family
EGY09_RS06270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY09_RS06285	COG1253	flavin adenine dinucleotide binding
EGY09_RS06305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGY09_RS06320	COG0504	CTP synthase activity
EGY09_RS06325	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EGY09_RS06340	COG0148	phosphopyruvate hydratase activity
EGY09_RS06345	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGY09_RS06350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGY09_RS06355	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EGY09_RS06365	COG2840	Smr protein MutS2
EGY09_RS06370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGY09_RS06375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGY09_RS06400	COG1534	Rna-binding protein
EGY09_RS06405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EGY09_RS06410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGY09_RS06430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGY09_RS06435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGY09_RS06440	COG1923	regulation of RNA biosynthetic process
EGY09_RS06445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGY09_RS06450	COG1546	Belongs to the CinA family
EGY09_RS06455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGY09_RS06460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGY09_RS06465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGY09_RS06470	COG2137	regulation of response to DNA damage stimulus
EGY09_RS06475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGY09_RS06480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGY09_RS06530	COG3540	Alkaline phosphatase
EGY09_RS06545	COG3258	Cytochrome c
EGY09_RS06560	COG2223	nitrite transmembrane transporter activity
EGY09_RS06575	COG1741	Belongs to the pirin family
EGY09_RS06580	COG0583	DNA-binding transcription factor activity
EGY09_RS06610	COG0351	phosphomethylpyrimidine kinase
EGY09_RS06610	COG0352	thiamine-phosphate diphosphorylase activity
EGY09_RS06625	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EGY09_RS06630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGY09_RS06640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGY09_RS06650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGY09_RS06655	COG0477	Major facilitator Superfamily
EGY09_RS06665	COG0617	tRNA 3'-terminal CCA addition
EGY09_RS06670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGY09_RS06675	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGY09_RS06680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGY09_RS06690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGY09_RS06695	COG0166	Belongs to the GPI family
EGY09_RS06700	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EGY09_RS06710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EGY09_RS06715	COG0671	phosphoesterase, PA-phosphatase related
EGY09_RS06725	COG0800	Aldolase
EGY09_RS06730	COG0129	dihydroxy-acid dehydratase activity
EGY09_RS06740	COG0837	glucose binding
EGY09_RS06765	COG2009	succinate dehydrogenase
EGY09_RS06770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGY09_RS06775	COG1053	succinate dehydrogenase
EGY09_RS06795	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGY09_RS06810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EGY09_RS06820	COG0552	protein localization to endoplasmic reticulum
EGY09_RS06840	COG0742	ribosomal rna small subunit methyltransferase
EGY09_RS06845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGY09_RS06855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGY09_RS06860	COG0405	Gamma-glutamyltransferase
EGY09_RS06865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY09_RS06885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGY09_RS06905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGY09_RS06915	COG0415	Belongs to the DNA photolyase family
EGY09_RS06920	COG2885	chlorophyll binding
EGY09_RS06925	COG0583	DNA-binding transcription factor activity
EGY09_RS07180	COG1802	Transcriptional regulator
EGY09_RS07180	COG4626	Terminase
EGY09_RS07185	COG4695	Portal protein
EGY09_RS07190	COG0740	serine-type endopeptidase activity
EGY09_RS07330	COG0582	viral genome integration into host DNA
EGY09_RS07345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGY09_RS07355	COG2914	Belongs to the UPF0125 (RnfH) family
EGY09_RS07360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGY09_RS07365	COG0735	belongs to the Fur family
EGY09_RS07375	COG0583	DNA-binding transcription factor activity
EGY09_RS07380	COG0497	DNA recombination
EGY09_RS07385	COG1420	regulation of RNA biosynthetic process
EGY09_RS07390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGY09_RS07395	COG0443	Heat shock 70 kDa protein
EGY09_RS07400	COG0484	heat shock protein binding
EGY09_RS07405	COG2207	Transcriptional regulator
EGY09_RS07410	COG2223	nitrite transmembrane transporter activity
EGY09_RS07415	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EGY09_RS07420	COG1605	Chorismate mutase
EGY09_RS07420	COG0287	Prephenate dehydrogenase
EGY09_RS07430	COG1132	(ABC) transporter
EGY09_RS07460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGY09_RS07465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGY09_RS07475	COG0343	queuine tRNA-ribosyltransferase activity
EGY09_RS07480	COG1862	Preprotein translocase
EGY09_RS07490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGY09_RS07495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EGY09_RS07505	COG2081	HI0933 family
EGY09_RS07510	COG4681	YaeQ
EGY09_RS07530	COG0625	glutathione transferase activity
EGY09_RS07535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGY09_RS07545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGY09_RS07550	COG0513	Belongs to the DEAD box helicase family
EGY09_RS07560	COG0583	DNA-binding transcription factor activity
EGY09_RS07565	COG0488	(ABC) transporter
EGY09_RS07590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS07605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGY09_RS07610	COG2957	Belongs to the agmatine deiminase family
EGY09_RS07620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGY09_RS07625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGY09_RS07635	COG0776	regulation of translation
EGY09_RS07645	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGY09_RS07650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGY09_RS07660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGY09_RS07665	COG0183	Belongs to the thiolase family
EGY09_RS07670	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGY09_RS07670	COG1024	Enoyl-CoA hydratase
EGY09_RS07680	COG0105	UTP biosynthetic process
EGY09_RS07685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGY09_RS07690	COG0859	PFAM glycosyl transferase family 9
EGY09_RS07690	COG0457	Tetratricopeptide repeat
EGY09_RS07695	COG1426	Protein conserved in bacteria
EGY09_RS07695	COG1426	Protein conserved in bacteria
EGY09_RS07705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGY09_RS07710	COG1160	GTP binding
EGY09_RS07735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGY09_RS07740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGY09_RS07740	COG0475	glutathione-regulated potassium exporter activity
EGY09_RS07755	COG0519	Catalyzes the synthesis of GMP from XMP
EGY09_RS07755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGY09_RS07760	COG2175	clavaminate synthase activity
EGY09_RS07780	COG0583	DNA-binding transcription factor activity
EGY09_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS07855	COG0640	Transcriptional regulator
EGY09_RS07870	COG4716	Myosin-crossreactive antigen
EGY09_RS07905	COG0431	NADPH-dependent FMN reductase
EGY09_RS07915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY09_RS07920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY09_RS07925	COG1473	amidohydrolase
EGY09_RS07935	COG1126	abc transporter atp-binding protein
EGY09_RS07940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGY09_RS07960	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGY09_RS07965	COG0583	DNA-binding transcription factor activity
EGY09_RS07970	COG0477	Major facilitator Superfamily
EGY09_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS07985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGY09_RS08005	COG1309	transcriptional regulator
EGY09_RS08020	COG0697	spore germination
EGY09_RS08025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGY09_RS08030	COG0167	dihydroorotate dehydrogenase activity
EGY09_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS08050	COG1012	belongs to the aldehyde dehydrogenase family
EGY09_RS08130	COG4191	Histidine kinase
EGY09_RS08130	COG0784	Response regulator, receiver
EGY09_RS08135	COG3437	response regulator, receiver
EGY09_RS08135	COG4999	Histidine kinase
EGY09_RS08135	COG3850	Histidine kinase
EGY09_RS08135	COG2205	protein histidine kinase activity
EGY09_RS08140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGY09_RS08160	COG0640	Transcriptional regulator
EGY09_RS08195	COG0460	homoserine dehydrogenase
EGY09_RS08195	COG0527	aspartate kinase activity
EGY09_RS08205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGY09_RS08210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY09_RS08215	COG0124	histidyl-tRNA synthetase
EGY09_RS08225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGY09_RS08230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGY09_RS08235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGY09_RS08240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGY09_RS08240	COG0131	Imidazoleglycerol-phosphate dehydratase
EGY09_RS08245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGY09_RS08250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGY09_RS08255	COG0107	imidazoleglycerol-phosphate synthase activity
EGY09_RS08260	COG0140	phosphoribosyl-ATP diphosphatase activity
EGY09_RS08260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGY09_RS08280	COG1446	asparaginase
EGY09_RS08285	COG3142	Participates in the control of copper homeostasis
EGY09_RS08300	COG2217	Heavy metal translocating P-type atpase
EGY09_RS08305	COG0789	Transcriptional regulator
EGY09_RS08320	COG3537	Alpha-1,2-mannosidase
EGY09_RS08325	COG1609	Transcriptional regulator
EGY09_RS08335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY09_RS08350	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EGY09_RS08355	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EGY09_RS08360	COG0235	Class ii aldolase
EGY09_RS08375	COG0531	amino acid
EGY09_RS08380	COG0531	amino acid
EGY09_RS08390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGY09_RS08395	COG0277	FAD linked oxidase domain protein
EGY09_RS08410	COG2205	protein histidine kinase activity
EGY09_RS08415	COG0745	RESPONSE REGULATOR receiver
EGY09_RS08425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS08440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGY09_RS08485	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY09_RS08500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGY09_RS08505	COG0505	Belongs to the CarA family
EGY09_RS08510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGY09_RS08515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGY09_RS08535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGY09_RS08540	COG4676	Protein conserved in bacteria
EGY09_RS08565	COG3279	Response regulator of the LytR AlgR family
EGY09_RS08580	COG1012	belongs to the aldehyde dehydrogenase family
EGY09_RS08585	COG0028	Belongs to the TPP enzyme family
EGY09_RS08600	COG2198	Histidine kinase
EGY09_RS08600	COG0784	Response regulator, receiver
EGY09_RS08600	COG2205	protein histidine kinase activity
EGY09_RS08605	COG1024	Enoyl-CoA hydratase
EGY09_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
EGY09_RS08615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EGY09_RS08620	COG1012	belongs to the aldehyde dehydrogenase family
EGY09_RS08625	COG1309	transcriptional regulator
EGY09_RS08630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGY09_RS08680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EGY09_RS08690	COG0840	transmembrane signaling receptor activity
EGY09_RS08695	COG0840	transmembrane signaling receptor activity
EGY09_RS08705	COG0835	chemotaxis
EGY09_RS08710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EGY09_RS08715	COG0840	transmembrane signaling receptor activity
EGY09_RS08725	COG0745	RESPONSE REGULATOR receiver
EGY09_RS08735	COG0835	chemotaxis
EGY09_RS08745	COG1360	Flagellar Motor Protein
EGY09_RS08750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EGY09_RS08755	COG0784	Response regulator, receiver
EGY09_RS08755	COG0643	Histidine kinase
EGY09_RS08755	COG2198	Histidine kinase
EGY09_RS08760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGY09_RS08785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGY09_RS08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGY09_RS08810	COG1987	bacterial-type flagellum assembly
EGY09_RS08820	COG3190	flagellar
EGY09_RS08870	COG1677	Flagellar hook-basal body complex protein FliE
EGY09_RS08895	COG2197	response regulator
EGY09_RS08915	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EGY09_RS08955	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EGY09_RS08965	COG4787	bacterial-type flagellum-dependent cell motility
EGY09_RS08980	COG1558	bacterial-type flagellum-dependent cell motility
EGY09_RS08985	COG1815	bacterial-type flagellum-dependent cell motility
EGY09_RS08990	COG0784	Response regulator, receiver
EGY09_RS08990	COG0835	chemotaxis
EGY09_RS09010	COG5002	protein histidine kinase activity
EGY09_RS09045	COG2915	High frequency lysogenization protein hflD homolog
EGY09_RS09050	COG0482	sulfurtransferase activity
EGY09_RS09065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGY09_RS09075	COG0542	response to heat
EGY09_RS09105	COG0492	ferredoxin-NADP+ reductase activity
EGY09_RS09110	COG1674	ftsk spoiiie
EGY09_RS09120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGY09_RS09125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGY09_RS09140	COG2819	hydrolase of the alpha beta superfamily
EGY09_RS09150	COG4558	Periplasmic binding protein
EGY09_RS09155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGY09_RS09160	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGY09_RS09170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGY09_RS09185	COG5002	protein histidine kinase activity
EGY09_RS09185	COG0784	Response regulator, receiver
EGY09_RS09215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGY09_RS09225	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EGY09_RS09240	COG1595	DNA-templated transcription, initiation
EGY09_RS09260	COG0784	Response regulator, receiver
EGY09_RS09265	COG4251	negative regulation of phosphorylation
EGY09_RS09275	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EGY09_RS09285	COG0454	-acetyltransferase
EGY09_RS09285	COG0456	acetyltransferase
EGY09_RS09290	COG2205	protein histidine kinase activity
EGY09_RS09295	COG4221	oxidoreductase activity
EGY09_RS09335	COG1309	transcriptional regulator
EGY09_RS09395	COG3685	Protein conserved in bacteria
EGY09_RS09420	COG3546	catalase activity
EGY09_RS09425	COG3685	Protein conserved in bacteria
EGY09_RS09450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGY09_RS09470	COG1063	alcohol dehydrogenase
EGY09_RS09500	COG1609	Transcriptional regulator
EGY09_RS09505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGY09_RS09505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGY09_RS09510	COG1105	Belongs to the carbohydrate kinase PfkB family
EGY09_RS09515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGY09_RS09515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGY09_RS09530	COG1733	regulation of RNA biosynthetic process
EGY09_RS09535	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EGY09_RS09550	COG4771	TonB-dependent receptor
EGY09_RS09555	COG0738	Major facilitator superfamily
EGY09_RS09560	COG1609	Transcriptional regulator
EGY09_RS09565	COG1472	Belongs to the glycosyl hydrolase 3 family
EGY09_RS09580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGY09_RS09595	COG2828	Protein conserved in bacteria
EGY09_RS09600	COG0583	DNA-binding transcription factor activity
EGY09_RS09630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGY09_RS09635	COG0583	DNA-binding transcription factor activity
EGY09_RS09665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY09_RS09690	COG2205	protein histidine kinase activity
EGY09_RS09700	COG0318	PFAM AMP-dependent synthetase and ligase
EGY09_RS09715	COG2186	Transcriptional regulator
EGY09_RS09735	COG2271	Major facilitator Superfamily
EGY09_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS09750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY09_RS09780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGY09_RS09800	COG0583	DNA-binding transcription factor activity
EGY09_RS09825	COG2204	response regulator
EGY09_RS09905	COG0708	Exodeoxyribonuclease III
EGY09_RS09910	COG0366	Alpha amylase catalytic
EGY09_RS09915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY09_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS09935	COG1136	(ABC) transporter
EGY09_RS09935	COG0577	efflux transmembrane transporter activity
EGY09_RS09940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS09950	COG0745	RESPONSE REGULATOR receiver
EGY09_RS09955	COG2205	protein histidine kinase activity
EGY09_RS09965	COG3214	Protein conserved in bacteria
EGY09_RS09975	COG4774	siderophore transport
EGY09_RS10005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EGY09_RS10010	COG1285	pathogenesis
EGY09_RS10015	COG4191	Histidine kinase
EGY09_RS10020	COG4566	intracellular signal transduction
EGY09_RS10120	COG0477	Major facilitator Superfamily
EGY09_RS10160	COG0583	DNA-binding transcription factor activity
EGY09_RS10165	COG0656	L-ascorbic acid biosynthetic process
EGY09_RS10185	COG2372	response to copper ion
EGY09_RS10200	COG5002	protein histidine kinase activity
EGY09_RS10205	COG0583	DNA-binding transcription factor activity
EGY09_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS10235	COG0642	Histidine kinase
EGY09_RS10240	COG3537	Alpha-1,2-mannosidase
EGY09_RS10255	COG0477	Major facilitator Superfamily
EGY09_RS10275	COG3920	Histidine kinase
EGY09_RS10275	COG2202	Pas domain
EGY09_RS10320	COG1335	isochorismatase
EGY09_RS10330	COG0402	S-adenosylhomocysteine deaminase activity
EGY09_RS10335	COG1335	isochorismatase
EGY09_RS10365	COG0811	peptide transport
EGY09_RS10505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGY09_RS10510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGY09_RS10520	COG0840	transmembrane signaling receptor activity
EGY09_RS10525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGY09_RS10535	COG4149	molybdate abc transporter
EGY09_RS10540	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGY09_RS10545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY09_RS10555	COG0746	molybdenum cofactor guanylyltransferase activity
EGY09_RS10560	COG0314	molybdopterin synthase activity
EGY09_RS10570	COG0303	'Molybdopterin
EGY09_RS10575	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGY09_RS10575	COG0315	cyclic pyranopterin monophosphate synthase activity
EGY09_RS10580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGY09_RS10605	COG2207	Transcriptional regulator
EGY09_RS10645	COG2205	protein histidine kinase activity
EGY09_RS10655	COG2194	sulfuric ester hydrolase activity
EGY09_RS10675	COG2885	chlorophyll binding
EGY09_RS10685	COG1943	Transposase
EGY09_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS10695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGY09_RS10695	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EGY09_RS10700	COG3433	isochorismatase activity
EGY09_RS10700	COG1535	isochorismatase
EGY09_RS10705	COG3433	isochorismatase activity
EGY09_RS10705	COG1535	isochorismatase
EGY09_RS10710	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGY09_RS10715	COG1169	isochorismate synthase
EGY09_RS10725	COG2409	Drug exporters of the RND superfamily
EGY09_RS10730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY09_RS10790	COG1914	H( )-stimulated, divalent metal cation uptake system
EGY09_RS10805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGY09_RS10810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGY09_RS10815	COG3321	synthase
EGY09_RS10815	COG0604	alcohol dehydrogenase
EGY09_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS10820	COG4206	TonB-dependent receptor
EGY09_RS10825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGY09_RS10870	COG4772	TonB-dependent receptor
EGY09_RS10890	COG2226	methyltransferase
EGY09_RS10935	COG4964	Belongs to the GSP D family
EGY09_RS10990	COG2814	Major facilitator Superfamily
EGY09_RS11000	COG1228	amidohydrolase
EGY09_RS11010	COG1335	isochorismatase
EGY09_RS11025	COG3850	Histidine kinase
EGY09_RS11030	COG2197	response regulator
EGY09_RS11035	COG2814	Major facilitator Superfamily
EGY09_RS11045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EGY09_RS11055	COG0583	DNA-binding transcription factor activity
EGY09_RS11070	COG3161	chorismate lyase activity
EGY09_RS11110	COG0277	FAD linked oxidase domain protein
EGY09_RS11115	COG1304	FMN binding
EGY09_RS11120	COG2186	Transcriptional regulator
EGY09_RS11130	COG1285	pathogenesis
EGY09_RS11160	COG2814	Major facilitator Superfamily
EGY09_RS11230	COG0587	DNA-directed DNA polymerase activity
EGY09_RS11245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGY09_RS11250	COG0519	Catalyzes the synthesis of GMP from XMP
EGY09_RS11250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGY09_RS11265	COG1595	DNA-templated transcription, initiation
EGY09_RS11275	COG1629	transport
EGY09_RS11275	COG4206	TonB-dependent receptor
EGY09_RS11305	COG0531	amino acid
EGY09_RS11320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY09_RS11330	COG0789	Transcriptional regulator
EGY09_RS11415	COG5001	Diguanylate cyclase
EGY09_RS11415	COG5002	protein histidine kinase activity
EGY09_RS11415	COG3447	MASE1 domain protein
EGY09_RS11420	COG2183	response to ionizing radiation
EGY09_RS11435	COG1983	PspC domain protein
EGY09_RS11445	COG3243	poly(R)-hydroxyalkanoic acid synthase
EGY09_RS11465	COG0534	Mate efflux family protein
EGY09_RS11485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGY09_RS11495	COG0668	transmembrane transport
EGY09_RS11500	COG1902	pentaerythritol trinitrate reductase activity
EGY09_RS11520	COG1733	regulation of RNA biosynthetic process
EGY09_RS11525	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY09_RS11530	COG0456	acetyltransferase
EGY09_RS11610	COG3702	type iv secretory pathway
EGY09_RS11630	COG2948	multi-organism process
EGY09_RS11640	COG3736	Type IV secretory pathway, component VirB8
EGY09_RS11650	COG3505	Type IV secretory pathway VirD4
EGY09_RS11665	COG2814	Major facilitator Superfamily
EGY09_RS11670	COG0789	Transcriptional regulator
EGY09_RS11705	COG0784	Response regulator, receiver
EGY09_RS11705	COG4191	Histidine kinase
EGY09_RS11720	COG4774	siderophore transport
EGY09_RS11740	COG1733	regulation of RNA biosynthetic process
EGY09_RS11745	COG0604	alcohol dehydrogenase
EGY09_RS11760	COG0210	DNA helicase
EGY09_RS11925	COG1192	Involved in chromosome partitioning
EGY09_RS12075	COG0210	DNA helicase
EGY09_RS12225	COG0583	DNA-binding transcription factor activity
EGY09_RS12230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGY09_RS12240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGY09_RS12255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGY09_RS12260	COG1605	Chorismate mutase
EGY09_RS12260	COG0077	Prephenate dehydratase
EGY09_RS12265	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGY09_RS12310	COG1228	amidohydrolase
EGY09_RS12325	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGY09_RS12420	COG4993	Dehydrogenase
EGY09_RS12430	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EGY09_RS12440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EGY09_RS12450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGY09_RS12455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGY09_RS12480	COG0359	binds to the 23S rRNA
EGY09_RS12485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGY09_RS12490	COG0360	Binds together with S18 to 16S ribosomal RNA
EGY09_RS12500	COG0316	Belongs to the HesB IscA family
EGY09_RS12505	COG0017	Asparaginyl-tRNA synthetase
EGY09_RS12525	COG0288	reversible hydration of carbon dioxide
EGY09_RS12535	COG3844	kynureninase activity
EGY09_RS12540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGY09_RS12545	COG2925	Exonuclease
EGY09_RS12570	COG2902	Dehydrogenase
EGY09_RS12580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS12585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS12600	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS12605	COG2226	methyltransferase
EGY09_RS12615	COG0646	methionine synthase
EGY09_RS12615	COG1410	methionine synthase
EGY09_RS12630	COG2900	Belongs to the SlyX family
EGY09_RS12645	COG0386	Belongs to the glutathione peroxidase family
EGY09_RS12655	COG1725	Transcriptional regulator
EGY09_RS12660	COG1131	(ABC) transporter
EGY09_RS12685	COG0114	fumarate hydratase activity
EGY09_RS12695	COG2850	peptidyl-arginine hydroxylation
EGY09_RS12705	COG0567	Dehydrogenase, E1 component
EGY09_RS12730	COG3540	Alkaline phosphatase
EGY09_RS12740	COG0305	Participates in initiation and elongation during chromosome replication
EGY09_RS12760	COG0625	glutathione transferase activity
EGY09_RS12780	COG0084	hydrolase, TatD family'
EGY09_RS12785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGY09_RS12820	COG0625	glutathione transferase activity
EGY09_RS12835	COG1595	DNA-templated transcription, initiation
EGY09_RS12840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGY09_RS12855	COG0386	Belongs to the glutathione peroxidase family
EGY09_RS12860	COG0339	signal peptide processing
EGY09_RS12870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGY09_RS12885	COG0705	Rhomboid family
EGY09_RS12890	COG3104	oligopeptide transport
EGY09_RS12900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGY09_RS12905	COG4290	ribonuclease
EGY09_RS12920	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGY09_RS12920	COG0316	Belongs to the HesB IscA family
EGY09_RS12925	COG2154	pterin-4-alpha-carbinolamine dehydratase
EGY09_RS12935	COG0428	transporter
EGY09_RS12945	COG1530	ribonuclease E activity
EGY09_RS12960	COG0395	ABC-type sugar transport system, permease component
EGY09_RS12990	COG0271	Belongs to the BolA IbaG family
EGY09_RS12995	COG2350	Protein conserved in bacteria
EGY09_RS13000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGY09_RS13005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGY09_RS13010	COG1187	pseudouridine synthase activity
EGY09_RS13020	COG2814	Major facilitator Superfamily
EGY09_RS13040	COG0436	Aminotransferase
EGY09_RS13045	COG4133	protoheme IX ABC transporter activity
EGY09_RS13065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EGY09_RS13080	COG3088	subunit of a heme lyase
EGY09_RS13080	COG4235	cytochrome complex assembly
EGY09_RS13090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGY09_RS13100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGY09_RS13105	COG4988	ABC transporter
EGY09_RS13115	COG1294	oxidase, subunit
EGY09_RS13145	COG0726	polysaccharide deacetylase
EGY09_RS13145	COG1649	PFAM Uncharacterised BCR, COG1649
EGY09_RS13150	COG1215	transferase activity, transferring glycosyl groups
EGY09_RS13160	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EGY09_RS13175	COG0165	Argininosuccinate lyase
EGY09_RS13180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGY09_RS13190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGY09_RS13195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGY09_RS13200	COG0137	argininosuccinate synthase activity
EGY09_RS13205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGY09_RS13220	COG2166	iron-sulfur cluster assembly
EGY09_RS13240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EGY09_RS13260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGY09_RS13265	COG0402	S-adenosylhomocysteine deaminase activity
EGY09_RS13270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGY09_RS13275	COG1509	lysine 2,3-aminomutase activity
EGY09_RS13280	COG5001	Diguanylate cyclase
EGY09_RS13280	COG3300	MHYT domain
EGY09_RS13300	COG0501	Belongs to the peptidase M48B family
EGY09_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS13330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGY09_RS13335	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGY09_RS13340	COG0802	atpase or kinase
EGY09_RS13345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGY09_RS13345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGY09_RS13350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGY09_RS13355	COG1570	exodeoxyribonuclease VII activity
EGY09_RS13365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGY09_RS13385	COG4771	TonB-dependent receptor
EGY09_RS13405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGY09_RS13405	COG2169	Transcriptional regulator
EGY09_RS13410	COG2130	NADP-dependent
EGY09_RS13435	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS13450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGY09_RS13485	COG2076	Multidrug Resistance protein
EGY09_RS13490	COG5487	UPF0391 membrane protein
EGY09_RS13495	COG1280	lysine exporter protein (LysE YggA)
EGY09_RS13500	COG1794	racemase activity, acting on amino acids and derivatives
EGY09_RS13535	COG0776	regulation of translation
EGY09_RS13540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY09_RS13540	COG0072	phenylalanine-tRNA ligase activity
EGY09_RS13545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGY09_RS13550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGY09_RS13555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGY09_RS13560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGY09_RS13565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGY09_RS13595	COG1185	polyribonucleotide nucleotidyltransferase activity
EGY09_RS13600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGY09_RS13610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGY09_RS13615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGY09_RS13620	COG0195	Participates in both transcription termination and antitermination
EGY09_RS13625	COG0779	Required for maturation of 30S ribosomal subunits
EGY09_RS13640	COG1007	ATP synthesis coupled electron transport
EGY09_RS13655	COG0713	ATP synthesis coupled electron transport
EGY09_RS13665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY09_RS13670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGY09_RS13685	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGY09_RS13690	COG0649	NAD binding
EGY09_RS13695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY09_RS13700	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY09_RS13705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY09_RS13720	COG0149	triose-phosphate isomerase activity
EGY09_RS13730	COG3083	sulfuric ester hydrolase activity
EGY09_RS13735	COG0438	transferase activity, transferring glycosyl groups
EGY09_RS13740	COG0726	polysaccharide deacetylase
EGY09_RS13745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGY09_RS13750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGY09_RS13755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGY09_RS13760	COG0159	tryptophan synthase activity
EGY09_RS13770	COG0133	tryptophan synthase activity
EGY09_RS13790	COG0135	phosphoribosylanthranilate isomerase activity
EGY09_RS13795	COG0101	tRNA pseudouridine synthase activity
EGY09_RS13810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGY09_RS13815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY09_RS13820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGY09_RS13825	COG2890	protein-(glutamine-N5) methyltransferase activity
EGY09_RS13830	COG1999	signal sequence binding
EGY09_RS13835	COG0688	phosphatidylethanolamine metabolic process
EGY09_RS13850	COG0433	COG0433 Predicted ATPase
EGY09_RS13855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGY09_RS13865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGY09_RS13870	COG0412	Dienelactone hydrolase
EGY09_RS13880	COG0717	Belongs to the dCTP deaminase family
EGY09_RS13890	COG0489	protein tyrosine kinase activity
EGY09_RS13895	COG4771	TonB-dependent receptor
EGY09_RS13900	COG4771	TonB-dependent receptor
EGY09_RS13905	COG0129	dihydroxy-acid dehydratase activity
EGY09_RS13910	COG3590	peptidase
EGY09_RS13940	COG0697	spore germination
EGY09_RS13950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY09_RS13955	COG2311	Membrane
EGY09_RS13960	COG1047	Peptidyl-prolyl cis-trans
EGY09_RS13965	COG0791	NLP P60 protein
EGY09_RS13970	COG0791	NLP P60 protein
EGY09_RS13975	COG1301	dicarboxylic acid transport
EGY09_RS13995	COG1722	exodeoxyribonuclease VII activity
EGY09_RS14000	COG0142	geranyltranstransferase activity
EGY09_RS14010	COG0312	modulator of DNA gyrase
EGY09_RS14015	COG3028	Belongs to the UPF0307 family
EGY09_RS14020	COG0312	modulator of DNA gyrase
EGY09_RS14040	COG2968	Membrane
EGY09_RS14050	COG4771	TonB-dependent receptor
EGY09_RS14065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGY09_RS14075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGY09_RS14090	COG0495	leucyl-tRNA aminoacylation
EGY09_RS14100	COG3118	belongs to the thioredoxin family
EGY09_RS14110	COG3706	GGDEF domain
EGY09_RS14110	COG4251	negative regulation of phosphorylation
EGY09_RS14110	COG2203	Gaf domain
EGY09_RS14110	COG5001	Diguanylate cyclase
EGY09_RS14130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGY09_RS14140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY09_RS14145	COG0346	lactoylglutathione lyase activity
EGY09_RS14155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY09_RS14155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY09_RS14165	COG2878	Part of a membrane complex involved in electron transport
EGY09_RS14170	COG0251	oxidation-reduction process
EGY09_RS14175	COG0392	lysyltransferase activity
EGY09_RS14175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EGY09_RS14205	COG2824	Alkylphosphonate utilization operon protein PhnA
EGY09_RS14210	COG0443	Heat shock 70 kDa protein
EGY09_RS14250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGY09_RS14255	COG3122	Protein conserved in bacteria
EGY09_RS14260	COG1451	nucleotide metabolic process
EGY09_RS14270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGY09_RS14290	COG0183	Belongs to the thiolase family
EGY09_RS14305	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS14315	COG1793	dna ligase
EGY09_RS14320	COG1201	RNA secondary structure unwinding
EGY09_RS14335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGY09_RS14340	COG1278	Cold shock
EGY09_RS14345	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGY09_RS14350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGY09_RS14355	COG1472	Belongs to the glycosyl hydrolase 3 family
EGY09_RS14360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGY09_RS14365	COG2954	triphosphatase activity
EGY09_RS14370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGY09_RS14375	COG0745	RESPONSE REGULATOR receiver
EGY09_RS14380	COG1381	Involved in DNA repair and RecF pathway recombination
EGY09_RS14385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGY09_RS14400	COG0681	Belongs to the peptidase S26 family
EGY09_RS14405	COG0481	GTPase activity
EGY09_RS14410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGY09_RS14430	COG1741	Belongs to the pirin family
EGY09_RS14435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGY09_RS14445	COG1741	Belongs to the pirin family
EGY09_RS14455	COG1966	Carbon starvation protein
EGY09_RS14460	COG2879	small protein
EGY09_RS14475	COG2205	protein histidine kinase activity
EGY09_RS14480	COG0745	RESPONSE REGULATOR receiver
EGY09_RS14525	COG2814	Major facilitator Superfamily
EGY09_RS14530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGY09_RS14530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGY09_RS14540	COG1113	amino acid transport
EGY09_RS14545	COG2207	Transcriptional regulator
EGY09_RS14545	COG1917	Cupin 2, conserved barrel domain protein
EGY09_RS14550	COG0753	catalase activity
EGY09_RS14580	COG1376	ErfK ybiS ycfS ynhG family protein
EGY09_RS14585	COG0739	heme binding
EGY09_RS14595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGY09_RS14605	COG0330	HflC and HflK could
EGY09_RS14610	COG0330	HflC and HflK could
EGY09_RS14615	COG0604	alcohol dehydrogenase
EGY09_RS14630	COG0678	peroxiredoxin activity
EGY09_RS14640	COG4953	penicillin-binding protein 1C
EGY09_RS14645	COG2373	Large extracellular alpha-helical protein
EGY09_RS14650	COG2079	MmgE PrpD family protein
EGY09_RS14655	COG2828	Protein conserved in bacteria
EGY09_RS14665	COG3609	addiction module antidote protein, CC2985 family
EGY09_RS14685	COG3829	transcription factor binding
EGY09_RS14705	COG0259	pyridoxamine-phosphate oxidase activity
EGY09_RS14720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGY09_RS14740	COG0477	Major facilitator Superfamily
EGY09_RS14750	COG0784	Response regulator, receiver
EGY09_RS14750	COG5002	protein histidine kinase activity
EGY09_RS14750	COG2198	Histidine kinase
EGY09_RS14765	COG3038	cytochrome b561
EGY09_RS14780	COG1760	l-serine dehydratase
EGY09_RS14785	COG2267	carboxylic ester hydrolase activity
EGY09_RS14790	COG0527	aspartate kinase activity
EGY09_RS14790	COG0460	homoserine dehydrogenase
EGY09_RS14795	COG0626	cystathionine gamma-synthase activity
EGY09_RS14800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGY09_RS14805	COG0739	heme binding
EGY09_RS14810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGY09_RS14815	COG1272	protein, Hemolysin III
EGY09_RS14820	COG2982	Protein involved in outer membrane biogenesis
EGY09_RS14830	COG0463	Glycosyl transferase, family 2
EGY09_RS14835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGY09_RS14840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGY09_RS14850	COG4206	TonB-dependent receptor
EGY09_RS14855	COG1309	transcriptional regulator
EGY09_RS14865	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS14895	COG0583	DNA-binding transcription factor activity
EGY09_RS14905	COG0509	glycine decarboxylation via glycine cleavage system
EGY09_RS14910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGY09_RS14920	COG0330	HflC and HflK could
EGY09_RS14930	COG1742	UPF0060 membrane protein
EGY09_RS14935	COG3956	TIGRFAM MazG family protein
EGY09_RS14945	COG0494	nUDIX hydrolase
EGY09_RS14955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGY09_RS14970	COG0784	Response regulator, receiver
EGY09_RS14970	COG0643	Histidine kinase
EGY09_RS14970	COG2198	Histidine kinase
EGY09_RS14975	COG0840	transmembrane signaling receptor activity
EGY09_RS14980	COG0835	chemotaxis
EGY09_RS14995	COG0189	ligase activity
EGY09_RS15010	COG1199	ATP-dependent helicase activity
EGY09_RS15025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGY09_RS15030	COG1215	transferase activity, transferring glycosyl groups
EGY09_RS15045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGY09_RS15055	COG1643	Atp-dependent helicase
EGY09_RS15060	COG0783	Belongs to the Dps family
EGY09_RS15065	COG0514	ATP-dependent DNA helicase (RecQ)
EGY09_RS15160	COG3772	lysozyme
EGY09_RS15330	COG0305	Participates in initiation and elongation during chromosome replication
EGY09_RS15460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGY09_RS15465	COG0602	queuosine metabolic process
EGY09_RS15475	COG2885	chlorophyll binding
EGY09_RS15480	COG0823	Involved in the tonB-independent uptake of proteins
EGY09_RS15495	COG0811	peptide transport
EGY09_RS15500	COG0824	Thioesterase
EGY09_RS15505	COG2255	four-way junction helicase activity
EGY09_RS15515	COG0632	four-way junction helicase activity
EGY09_RS15520	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EGY09_RS15525	COG0217	transcriptional regulatory protein
EGY09_RS15545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGY09_RS15575	COG0488	(ABC) transporter
EGY09_RS15600	COG4651	solute:proton antiporter activity
EGY09_RS15600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGY09_RS15610	COG0745	RESPONSE REGULATOR receiver
EGY09_RS15615	COG2205	protein histidine kinase activity
EGY09_RS15625	COG0542	response to heat
EGY09_RS15650	COG0028	Belongs to the TPP enzyme family
EGY09_RS15675	COG3387	PFAM Glycoside hydrolase 15-related
EGY09_RS15680	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGY09_RS15685	COG3011	Protein conserved in bacteria
EGY09_RS15700	COG0564	pseudouridine synthase activity
EGY09_RS15705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGY09_RS15715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGY09_RS15715	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGY09_RS15725	COG0045	succinate-CoA ligase (ADP-forming) activity
EGY09_RS15760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EGY09_RS15780	COG0745	RESPONSE REGULATOR receiver
EGY09_RS15795	COG0189	ligase activity
EGY09_RS15820	COG4625	pathogenesis
EGY09_RS15820	COG3240	lipase activity
EGY09_RS15830	COG2022	thiamine diphosphate biosynthetic process
EGY09_RS15835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGY09_RS15840	COG0471	metal ion transport
EGY09_RS15840	COG3273	potassium ion transport
EGY09_RS15860	COG1970	mechanosensitive ion channel activity
EGY09_RS15870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY09_RS15875	COG1115	amino acid carrier protein
EGY09_RS15885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS15915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGY09_RS15925	COG3588	fructose-bisphosphate aldolase
EGY09_RS15930	COG0469	pyruvate kinase activity
EGY09_RS15940	COG0126	phosphoglycerate kinase activity
EGY09_RS15955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGY09_RS16000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGY09_RS16005	COG1301	dicarboxylic acid transport
EGY09_RS16035	COG0714	Associated with various cellular activities
EGY09_RS16065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGY09_RS16080	COG5295	Hep Hag repeat protein
EGY09_RS16115	COG0254	rRNA binding
EGY09_RS16125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGY09_RS16135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGY09_RS16140	COG1758	RNA polymerase activity
EGY09_RS16150	COG3383	formate dehydrogenase (NAD+) activity
EGY09_RS16150	COG0243	molybdopterin cofactor binding
EGY09_RS16155	COG3383	formate dehydrogenase (NAD+) activity
EGY09_RS16155	COG0243	molybdopterin cofactor binding
EGY09_RS16160	COG0437	4 iron, 4 sulfur cluster binding
EGY09_RS16165	COG2864	formate dehydrogenase
EGY09_RS16175	COG1921	L-seryl-tRNASec selenium transferase activity
EGY09_RS16180	COG3276	selenocysteine insertion sequence binding
EGY09_RS16190	COG0709	Synthesizes selenophosphate from selenide and ATP
EGY09_RS16195	COG1561	YicC-like family, N-terminal region
EGY09_RS16200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGY09_RS16205	COG0346	lactoylglutathione lyase activity
EGY09_RS16215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGY09_RS16230	COG0006	proline dipeptidase activity
EGY09_RS16235	COG0006	proline dipeptidase activity
EGY09_RS16240	COG3079	Belongs to the UPF0149 family
EGY09_RS16260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGY09_RS16270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGY09_RS16280	COG2912	Transglutaminase-like superfamily
EGY09_RS16285	COG1773	rubredoxin
EGY09_RS16295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGY09_RS16300	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EGY09_RS16310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGY09_RS16315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY09_RS16325	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS16345	COG0671	phosphoesterase, PA-phosphatase related
EGY09_RS16355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGY09_RS16360	COG0563	adenylate kinase activity
EGY09_RS16380	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EGY09_RS16390	COG0848	biopolymer transport protein
EGY09_RS16400	COG2832	Protein of unknown function (DUF454)
EGY09_RS16435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGY09_RS16460	COG0745	RESPONSE REGULATOR receiver
EGY09_RS16470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGY09_RS16475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGY09_RS16480	COG0405	Gamma-glutamyltransferase
EGY09_RS16485	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGY09_RS16505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGY09_RS16510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGY09_RS16525	COG0473	3-isopropylmalate dehydrogenase activity
EGY09_RS16540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS16555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGY09_RS16560	COG1538	Outer membrane efflux protein
EGY09_RS16565	COG0531	amino acid
EGY09_RS16570	COG1519	Transferase
EGY09_RS16575	COG1560	Kdo2-lipid A biosynthetic process
EGY09_RS16620	COG1301	dicarboxylic acid transport
EGY09_RS16630	COG4191	Histidine kinase
EGY09_RS16645	COG0642	Histidine kinase
EGY09_RS16660	COG2851	Citrate transporter
EGY09_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS16690	COG1162	GTPase activity
EGY09_RS16695	COG0436	Aminotransferase
EGY09_RS16715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGY09_RS16730	COG1228	amidohydrolase
EGY09_RS16735	COG0804	urea catabolic process
EGY09_RS16745	COG1307	EDD domain protein, DegV family
EGY09_RS16785	COG2203	Gaf domain
EGY09_RS16785	COG3706	GGDEF domain
EGY09_RS16785	COG5001	Diguanylate cyclase
EGY09_RS16785	COG4251	negative regulation of phosphorylation
EGY09_RS16790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGY09_RS16800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EGY09_RS16820	COG1902	pentaerythritol trinitrate reductase activity
EGY09_RS16845	COG0583	DNA-binding transcription factor activity
EGY09_RS16850	COG1064	alcohol dehydrogenase
EGY09_RS16870	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EGY09_RS16875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGY09_RS16885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGY09_RS16890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGY09_RS16905	COG1522	sequence-specific DNA binding
EGY09_RS16915	COG4773	Receptor
EGY09_RS16920	COG4206	TonB-dependent receptor
EGY09_RS16935	COG0617	tRNA 3'-terminal CCA addition
EGY09_RS16970	COG3468	outer membrane autotransporter barrel domain protein
EGY09_RS16980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGY09_RS16985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGY09_RS16990	COG1609	Transcriptional regulator
EGY09_RS17000	COG0837	glucose binding
EGY09_RS17010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EGY09_RS17030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGY09_RS17050	COG4191	Histidine kinase
EGY09_RS17055	COG0784	Response regulator, receiver
EGY09_RS17060	COG4251	negative regulation of phosphorylation
EGY09_RS17065	COG2823	Periplasmic or secreted lipoprotein
EGY09_RS17070	COG0673	inositol 2-dehydrogenase activity
EGY09_RS17075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EGY09_RS17095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGY09_RS17105	COG2921	Belongs to the UPF0250 family
EGY09_RS17115	COG1686	Belongs to the peptidase S11 family
EGY09_RS17120	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGY09_RS17125	COG2951	lytic endotransglycosylase activity
EGY09_RS17130	COG0772	Belongs to the SEDS family
EGY09_RS17135	COG0772	Belongs to the SEDS family
EGY09_RS17150	COG1792	Involved in formation and maintenance of cell shape
EGY09_RS17155	COG1077	Cell shape determining protein MreB Mrl
EGY09_RS17160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY09_RS17175	COG0308	aminopeptidase N
EGY09_RS17180	COG2226	methyltransferase
EGY09_RS17210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS17225	COG0673	inositol 2-dehydrogenase activity
EGY09_RS17235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGY09_RS17250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGY09_RS17260	COG2832	Protein of unknown function (DUF454)
EGY09_RS17270	COG0436	Aminotransferase
EGY09_RS17275	COG1505	serine-type exopeptidase activity
EGY09_RS17300	COG0697	spore germination
EGY09_RS17305	COG1666	GTP binding
EGY09_RS17320	COG0339	signal peptide processing
EGY09_RS17330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGY09_RS17350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGY09_RS17360	COG1136	(ABC) transporter
EGY09_RS17365	COG0577	efflux transmembrane transporter activity
EGY09_RS17365	COG1136	(ABC) transporter
EGY09_RS17370	COG0577	efflux transmembrane transporter activity
EGY09_RS17380	COG2204	response regulator
EGY09_RS17385	COG4191	Histidine kinase
EGY09_RS17395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGY09_RS17405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGY09_RS17410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGY09_RS17415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGY09_RS17420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGY09_RS17425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGY09_RS17430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGY09_RS17440	COG0356	it plays a direct role in the translocation of protons across the membrane
EGY09_RS17455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGY09_RS17460	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGY09_RS17480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGY09_RS17505	COG0181	hydroxymethylbilane synthase activity
EGY09_RS17515	COG2972	Histidine kinase
EGY09_RS17515	COG0745	RESPONSE REGULATOR receiver
EGY09_RS17535	COG4771	TonB-dependent receptor
EGY09_RS17565	COG0477	Major facilitator Superfamily
EGY09_RS17610	COG4206	TonB-dependent receptor
EGY09_RS17630	COG0625	glutathione transferase activity
EGY09_RS17645	COG2259	Doxx family
EGY09_RS17700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGY09_RS17705	COG1490	D-aminoacyl-tRNA deacylase activity
EGY09_RS17715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY09_RS17750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGY09_RS17750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGY09_RS17755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGY09_RS17760	COG0242	peptide deformylase activity
EGY09_RS17770	COG0758	DNA mediated transformation
EGY09_RS17775	COG2922	Belongs to the Smg family
EGY09_RS17785	COG1714	RDD family
EGY09_RS17790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGY09_RS17790	COG1754	DNA topoisomerase type I activity
EGY09_RS17795	COG0009	L-threonylcarbamoyladenylate synthase
EGY09_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS17820	COG0616	signal peptide processing
EGY09_RS17825	COG0534	Mate efflux family protein
EGY09_RS17840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGY09_RS17845	COG0625	glutathione transferase activity
EGY09_RS17855	COG1252	NADH dehydrogenase
EGY09_RS17875	COG2860	membrane
EGY09_RS17885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGY09_RS17910	COG1846	Transcriptional regulator
EGY09_RS17940	COG0459	protein refolding
EGY09_RS17945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGY09_RS17950	COG2356	endonuclease I
EGY09_RS17955	COG1324	tolerance protein
EGY09_RS17960	COG4232	protein-disulfide reductase activity
EGY09_RS17965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY09_RS17980	COG0840	transmembrane signaling receptor activity
EGY09_RS18000	COG4585	Histidine kinase
EGY09_RS18020	COG0583	DNA-binding transcription factor activity
EGY09_RS18030	COG1785	Belongs to the alkaline phosphatase family
EGY09_RS18035	COG1686	Belongs to the peptidase S11 family
EGY09_RS18045	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY09_RS18055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EGY09_RS18065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGY09_RS18070	COG0511	ligase activity, forming carbon-carbon bonds
EGY09_RS18075	COG0439	Biotin carboxylase
EGY09_RS18090	COG2264	protein methyltransferase activity
EGY09_RS18100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGY09_RS18105	COG4589	Belongs to the CDS family
EGY09_RS18110	COG0204	Acyl-transferase
EGY09_RS18120	COG0671	phosphoesterase, PA-phosphatase related
EGY09_RS18120	COG2453	phosphatase
EGY09_RS18125	COG2267	carboxylic ester hydrolase activity
EGY09_RS18130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGY09_RS18135	COG0138	bifunctional purine biosynthesis protein purh
EGY09_RS18140	COG0151	Belongs to the GarS family
EGY09_RS18155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGY09_RS18160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGY09_RS18165	COG2201	protein-glutamate methylesterase activity
EGY09_RS18170	COG2177	Part of the ABC transporter FtsEX involved in
EGY09_RS18175	COG2884	Cell division ATP-binding protein ftsE
EGY09_RS18190	COG3118	belongs to the thioredoxin family
EGY09_RS18195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGY09_RS18200	COG3706	GGDEF domain
EGY09_RS18210	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EGY09_RS18245	COG1652	LysM domain
EGY09_RS18250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGY09_RS18250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGY09_RS18255	COG1473	amidohydrolase
EGY09_RS18260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS18265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS18270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGY09_RS18275	COG1289	transmembrane transporter activity
EGY09_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS18285	COG2814	Major facilitator Superfamily
EGY09_RS18315	COG0316	Belongs to the HesB IscA family
EGY09_RS18355	COG1051	belongs to the nudix hydrolase family
EGY09_RS18370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGY09_RS18375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGY09_RS18380	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EGY09_RS18390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EGY09_RS18395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY09_RS18400	COG0730	response to heat
EGY09_RS18410	COG0134	indole-3-glycerol-phosphate synthase activity
EGY09_RS18415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGY09_RS18435	COG1597	lipid kinase activity
EGY09_RS18450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGY09_RS18455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGY09_RS18465	COG2111	Na H antiporter
EGY09_RS18465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGY09_RS18470	COG1006	Multisubunit Na H antiporter MnhC subunit
EGY09_RS18475	COG0651	ATP synthesis coupled electron transport
EGY09_RS18480	COG1863	multisubunit Na H antiporter MnhE subunit
EGY09_RS18485	COG2212	antiporter activity
EGY09_RS18490	COG1320	monovalent cation:proton antiporter activity
EGY09_RS18495	COG0530	calcium, potassium:sodium antiporter activity
EGY09_RS18510	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EGY09_RS18535	COG3104	oligopeptide transport
EGY09_RS18540	COG3483	tryptophan 2,3-dioxygenase activity
EGY09_RS18575	COG2378	regulation of single-species biofilm formation
EGY09_RS18590	COG2354	Protein conserved in bacteria
EGY09_RS18595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGY09_RS18600	COG1368	sulfuric ester hydrolase activity
EGY09_RS18605	COG3264	Mechanosensitive ion channel
EGY09_RS18605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EGY09_RS18620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGY09_RS18655	COG1166	arginine decarboxylase activity
EGY09_RS18660	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EGY09_RS18680	COG2960	long-chain fatty acid transporting porin activity
EGY09_RS18745	COG0606	chelatase, subunit chli
EGY09_RS18760	COG0561	phosphatase activity
EGY09_RS18765	COG3932	Exopolysaccharide synthesis, ExoD
EGY09_RS18790	COG1999	signal sequence binding
EGY09_RS18795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGY09_RS18800	COG1845	cytochrome c oxidase, subunit III
EGY09_RS18810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGY09_RS18815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY09_RS18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY09_RS18835	COG1104	cysteine desulfurase activity
EGY09_RS18885	COG2031	fatty acid transporter
EGY09_RS18930	COG0673	inositol 2-dehydrogenase activity
EGY09_RS18940	COG1501	Belongs to the glycosyl hydrolase 31 family
EGY09_RS18945	COG2222	sugar isomerase
EGY09_RS18950	COG1940	carbohydrate kinase activity
EGY09_RS18960	COG1349	DNA-binding transcription factor activity
EGY09_RS18965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGY09_RS18970	COG2814	Major facilitator Superfamily
EGY09_RS19000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGY09_RS19005	COG0156	8-amino-7-oxononanoate synthase activity
EGY09_RS19010	COG2267	carboxylic ester hydrolase activity
EGY09_RS19030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGY09_RS19060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY09_RS19065	COG2205	protein histidine kinase activity
EGY09_RS19070	COG0745	RESPONSE REGULATOR receiver
EGY09_RS19075	COG3541	Predicted nucleotidyltransferase
EGY09_RS19080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGY09_RS19105	COG0714	Associated with various cellular activities
EGY09_RS19120	COG0754	glutathionylspermidine amidase activity
EGY09_RS19135	COG0129	dihydroxy-acid dehydratase activity
EGY09_RS19140	COG2311	Membrane
EGY09_RS19145	COG1199	ATP-dependent helicase activity
EGY09_RS19155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGY09_RS19175	COG3781	membrane
EGY09_RS19205	COG0625	glutathione transferase activity
EGY09_RS19225	COG2207	Transcriptional regulator
EGY09_RS19240	COG4555	ABC transporter
EGY09_RS19270	COG0633	Ferredoxin
EGY09_RS19270	COG0543	2 iron, 2 sulfur cluster binding
EGY09_RS19275	COG1131	(ABC) transporter
EGY09_RS19280	COG0842	Transport permease protein
EGY09_RS19290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGY09_RS19300	COG0084	hydrolase, TatD family'
EGY09_RS19310	COG1643	Atp-dependent helicase
EGY09_RS19320	COG1187	pseudouridine synthase activity
EGY09_RS19340	COG0667	Aldo Keto reductase
EGY09_RS19355	COG1690	Belongs to the RtcB family
EGY09_RS19370	COG0840	transmembrane signaling receptor activity
EGY09_RS19375	COG0583	DNA-binding transcription factor activity
EGY09_RS19380	COG2814	Major facilitator Superfamily
EGY09_RS19385	COG0656	L-ascorbic acid biosynthetic process
EGY09_RS19405	COG2267	carboxylic ester hydrolase activity
EGY09_RS19430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGY09_RS19430	COG1042	CoA-binding domain protein
EGY09_RS19430	COG0045	succinate-CoA ligase (ADP-forming) activity
EGY09_RS19435	COG2239	Acts as a magnesium transporter
EGY09_RS19445	COG3177	Filamentation induced by cAMP protein fic
EGY09_RS19445	COG0666	response to abiotic stimulus
EGY09_RS19450	COG3100	YcgL domain-containing protein
EGY09_RS19460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY09_RS19465	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS19475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY09_RS19485	COG0644	oxidoreductase
EGY09_RS19505	COG2986	histidine ammonia-lyase
EGY09_RS19515	COG0463	Glycosyl transferase, family 2
EGY09_RS19530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGY09_RS19535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGY09_RS19550	COG1294	oxidase, subunit
EGY09_RS19555	COG1271	oxidase subunit
EGY09_RS19590	COG1595	DNA-templated transcription, initiation
EGY09_RS19625	COG0408	coproporphyrinogen oxidase activity
EGY09_RS19635	COG2323	membrane
EGY09_RS19650	COG0589	response to stress
EGY09_RS19675	COG0210	DNA helicase
EGY09_RS19685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGY09_RS19690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGY09_RS19695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGY09_RS19700	COG1819	glycosyl
EGY09_RS19715	COG0251	oxidation-reduction process
EGY09_RS19750	COG0463	Glycosyl transferase, family 2
EGY09_RS19765	COG1475	DNA binding
EGY09_RS19770	COG1192	Involved in chromosome partitioning
EGY09_RS19775	COG0357	Ribosomal RNA small subunit methyltransferase G
EGY09_RS19780	COG2091	lysine biosynthetic process via aminoadipic acid
EGY09_RS19820	COG1971	Probably functions as a manganese efflux pump
EGY09_RS19825	COG2205	protein histidine kinase activity
EGY09_RS19825	COG0784	Response regulator, receiver
EGY09_RS19840	COG2911	Protein conserved in bacteria
EGY09_RS19845	COG0729	surface antigen
EGY09_RS19855	COG0752	glycyl-tRNA synthetase alpha subunit
EGY09_RS19860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGY09_RS19865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGY09_RS19865	COG0519	Catalyzes the synthesis of GMP from XMP
EGY09_RS19875	COG0805	protein transport
EGY09_RS19885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGY09_RS19895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGY09_RS19900	COG0596	Alpha beta hydrolase
EGY09_RS19900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGY09_RS19905	COG0840	transmembrane signaling receptor activity
EGY09_RS19960	COG3135	benzoate transporter
EGY09_RS19975	COG2951	lytic endotransglycosylase activity
EGY09_RS19980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EGY09_RS19985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGY09_RS19990	COG3706	GGDEF domain
EGY09_RS20020	COG0302	gtp cyclohydrolase
EGY09_RS20035	COG1566	PFAM secretion protein HlyD family protein
EGY09_RS20045	COG1289	transmembrane transporter activity
EGY09_RS20060	COG1074	ATP-dependent DNA helicase activity
EGY09_RS20065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGY09_RS20070	COG1127	ABC transporter
EGY09_RS20075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGY09_RS20080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGY09_RS20095	COG2853	Lipoprotein
EGY09_RS20100	COG0386	Belongs to the glutathione peroxidase family
EGY09_RS20110	COG1322	Protein conserved in bacteria
EGY09_RS20125	COG0583	DNA-binding transcription factor activity
EGY09_RS20145	COG0531	amino acid
EGY09_RS20155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGY09_RS20160	COG0861	Integral membrane protein TerC family
EGY09_RS20170	COG0584	glycerophosphoryl diester phosphodiesterase
EGY09_RS20185	COG0706	membrane insertase activity
EGY09_RS20190	COG0594	ribonuclease P activity
EGY09_RS20195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGY09_RS20200	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGY09_RS20210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGY09_RS20215	COG0187	DNA topoisomerase II activity
EGY09_RS20220	COG1266	CAAX protease self-immunity
EGY09_RS20225	COG0501	Belongs to the peptidase M48B family
EGY09_RS20280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGY09_RS20290	COG4772	TonB-dependent receptor
EGY09_RS20325	COG0800	Aldolase
EGY09_RS20340	COG3186	Phenylalanine-4-hydroxylase
EGY09_RS20345	COG1522	sequence-specific DNA binding
EGY09_RS20350	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGY09_RS20380	COG1119	ATPase activity
EGY09_RS20395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGY09_RS20400	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EGY09_RS20420	COG0210	DNA helicase
EGY09_RS20430	COG3132	Protein of unknown function, DUF480
EGY09_RS20435	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EGY09_RS20440	COG0284	orotidine-5'-phosphate decarboxylase activity
EGY09_RS20450	COG2937	Belongs to the GPAT DAPAT family
EGY09_RS20460	COG0037	tRNA processing
EGY09_RS20465	COG2974	May be involved in recombination
EGY09_RS20475	COG1803	Methylglyoxal synthase
EGY09_RS20480	COG2205	protein histidine kinase activity
EGY09_RS20480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGY09_RS20485	COG0493	'glutamate synthase
EGY09_RS20490	COG0069	glutamate synthase activity
EGY09_RS20490	COG0067	glutamate synthase
EGY09_RS20490	COG0070	glutamate synthase
EGY09_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
EGY09_RS20525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY09_RS20550	COG1111	helicase
EGY09_RS20550	COG1205	dead DEAH box helicase
EGY09_RS20585	COG0714	Associated with various cellular activities
EGY09_RS20605	COG0312	modulator of DNA gyrase
EGY09_RS20625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGY09_RS20645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGY09_RS20670	COG1881	PFAM PEBP family protein
EGY09_RS20685	COG1968	undecaprenyl-diphosphatase activity
EGY09_RS20690	COG0174	glutamine synthetase
EGY09_RS20695	COG0347	Belongs to the P(II) protein family
EGY09_RS20700	COG0004	ammonium transporteR
EGY09_RS20705	COG2831	hemolysin activation secretion protein
EGY09_RS20710	COG3210	domain, Protein
EGY09_RS20710	COG3210	domain, Protein
EGY09_RS20725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGY09_RS20740	COG3852	Histidine kinase
EGY09_RS20745	COG2204	response regulator
EGY09_RS20750	COG2032	superoxide dismutase activity
EGY09_RS20755	COG2032	superoxide dismutase activity
EGY09_RS20765	COG0183	Belongs to the thiolase family
EGY09_RS20800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EGY09_RS20805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGY09_RS20825	COG0798	PFAM Bile acid sodium symporter
EGY09_RS20840	COG0431	NADPH-dependent FMN reductase
EGY09_RS20875	COG2837	iron assimilation
EGY09_RS20915	COG2197	response regulator
EGY09_RS20920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGY09_RS20920	COG2205	protein histidine kinase activity
EGY09_RS20925	COG3474	cytochrome
EGY09_RS20935	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS20940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGY09_RS20950	COG0612	Peptidase, M16
EGY09_RS20960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY09_RS20965	COG0596	Alpha beta hydrolase
EGY09_RS20975	COG0318	PFAM AMP-dependent synthetase and ligase
EGY09_RS20980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGY09_RS20990	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGY09_RS21000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGY09_RS21015	COG1215	transferase activity, transferring glycosyl groups
EGY09_RS21020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGY09_RS21050	COG0339	signal peptide processing
EGY09_RS21065	COG0681	Belongs to the peptidase S26 family
EGY09_RS21070	COG2814	Major facilitator Superfamily
EGY09_RS21075	COG0583	DNA-binding transcription factor activity
EGY09_RS21080	COG0583	DNA-binding transcription factor activity
EGY09_RS21085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGY09_RS21090	COG2224	Isocitrate lyase
EGY09_RS21095	COG3706	GGDEF domain
EGY09_RS21120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGY09_RS21125	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS21145	COG0697	spore germination
EGY09_RS21155	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGY09_RS21165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGY09_RS21175	COG1280	lysine exporter protein (LysE YggA)
EGY09_RS21180	COG1607	acyl-coa hydrolase
EGY09_RS21190	COG1902	pentaerythritol trinitrate reductase activity
EGY09_RS21205	COG1335	isochorismatase
EGY09_RS21210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGY09_RS21220	COG1051	belongs to the nudix hydrolase family
EGY09_RS21220	COG1056	cytidyltransferase-related domain
EGY09_RS21225	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGY09_RS21235	COG3800	Transcriptional regulator
EGY09_RS21235	COG1396	sequence-specific DNA binding
EGY09_RS21245	COG1960	acyl-CoA dehydrogenase activity
EGY09_RS21250	COG1024	Enoyl-CoA hydratase
EGY09_RS21255	COG1024	Enoyl-CoA hydratase
EGY09_RS21265	COG1764	response to oxidative stress
EGY09_RS21290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGY09_RS21320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGY09_RS21320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGY09_RS21325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EGY09_RS21380	COG3237	CsbD-like
EGY09_RS21390	COG0180	Tryptophanyl-tRNA synthetase
EGY09_RS21415	COG0477	Major facilitator Superfamily