locus-tag	class	description
AL480_RS00005	COG0740	serine-type endopeptidase activity
AL480_RS00010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL480_RS00050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL480_RS00055	COG3942	CHAP domain
AL480_RS00055	COG1388	LysM domain
AL480_RS00060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL480_RS00070	COG0328	RNA-DNA hybrid ribonuclease activity
AL480_RS00075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL480_RS00080	COG0631	protein serine/threonine phosphatase activity
AL480_RS00110	COG0859	PFAM glycosyl transferase family 9
AL480_RS00115	COG3642	lipopolysaccharide core region biosynthetic process
AL480_RS00120	COG1234	tRNA 3'-trailer cleavage
AL480_RS00135	COG2076	Multidrug Resistance protein
AL480_RS00170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL480_RS00180	COG0537	adenosine 5'-monophosphoramidase activity
AL480_RS00200	COG0714	Associated with various cellular activities
AL480_RS00215	COG1399	metal-binding, possibly nucleic acid-binding protein
AL480_RS00220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL480_RS00225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL480_RS00235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL480_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS00250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL480_RS00255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL480_RS00260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL480_RS00265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL480_RS00295	COG4626	Terminase
AL480_RS00295	COG1802	Transcriptional regulator
AL480_RS00515	COG4774	siderophore transport
AL480_RS00530	COG2223	nitrite transmembrane transporter activity
AL480_RS00545	COG2226	methyltransferase
AL480_RS00555	COG0583	DNA-binding transcription factor activity
AL480_RS00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL480_RS00565	COG0697	spore germination
AL480_RS00570	COG0583	DNA-binding transcription factor activity
AL480_RS00575	COG0477	Major facilitator Superfamily
AL480_RS00610	COG0583	DNA-binding transcription factor activity
AL480_RS00620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL480_RS00635	COG0667	Aldo Keto reductase
AL480_RS00655	COG2818	Glycosylase
AL480_RS00660	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL480_RS00665	COG1678	Uncharacterized ACR, COG1678
AL480_RS00670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL480_RS00675	COG0540	Belongs to the ATCase OTCase family
AL480_RS00695	COG2239	Acts as a magnesium transporter
AL480_RS00700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL480_RS00715	COG1660	Displays ATPase and GTPase activities
AL480_RS00720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL480_RS00725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL480_RS00730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL480_RS00740	COG1137	ATPase activity
AL480_RS00755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL480_RS00770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL480_RS00790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL480_RS00810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL480_RS00820	COG0628	permease
AL480_RS00830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL480_RS00835	COG3178	'Phosphotransferase
AL480_RS00840	COG2261	transglycosylase associated protein
AL480_RS00850	COG1555	photosystem II stabilization
AL480_RS00870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL480_RS00875	COG1477	protein flavinylation
AL480_RS00895	COG4771	TonB-dependent receptor
AL480_RS00905	COG3128	pkhd-type hydroxylase
AL480_RS00915	COG4774	siderophore transport
AL480_RS00925	COG2146	nitrite reductase [NAD(P)H] activity
AL480_RS00940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL480_RS00945	COG0719	Fe-S assembly protein
AL480_RS00950	COG0396	ATPase activity
AL480_RS00960	COG0719	Fe-S assembly protein
AL480_RS00965	COG1959	2 iron, 2 sulfur cluster binding
AL480_RS00975	COG0693	protein deglycase activity
AL480_RS01000	COG1764	response to oxidative stress
AL480_RS01005	COG0384	phenazine biosynthesis protein PhzF
AL480_RS01010	COG0384	phenazine biosynthesis protein PhzF
AL480_RS01015	COG0527	aspartate kinase activity
AL480_RS01045	COG0142	geranyltranstransferase activity
AL480_RS01050	COG0366	Alpha amylase catalytic
AL480_RS01065	COG1082	Xylose isomerase domain protein TIM barrel
AL480_RS01075	COG2211	Major facilitator Superfamily
AL480_RS01075	COG2190	(PTS) system
AL480_RS01105	COG1131	(ABC) transporter
AL480_RS01115	COG0629	single-stranded DNA binding
AL480_RS01195	COG0673	inositol 2-dehydrogenase activity
AL480_RS01200	COG2211	Major facilitator Superfamily
AL480_RS01210	COG1609	Transcriptional regulator
AL480_RS01250	COG0640	Transcriptional regulator
AL480_RS01265	COG3655	Transcriptional regulator
AL480_RS01270	COG1253	flavin adenine dinucleotide binding
AL480_RS01275	COG1408	metallophosphoesterase
AL480_RS01280	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL480_RS01300	COG2259	Doxx family
AL480_RS01330	COG0477	Major facilitator Superfamily
AL480_RS01345	COG1802	Transcriptional regulator
AL480_RS01380	COG3052	prosthetic group binding
AL480_RS01395	COG0579	oxidoreductase
AL480_RS01420	COG3104	oligopeptide transport
AL480_RS01435	COG1297	OPT oligopeptide transporter protein
AL480_RS01440	COG1506	peptidase
AL480_RS01440	COG0823	Involved in the tonB-independent uptake of proteins
AL480_RS01455	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL480_RS01460	COG2894	cell division
AL480_RS01475	COG4585	Histidine kinase
AL480_RS01480	COG2197	response regulator
AL480_RS01520	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL480_RS01530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL480_RS01540	COG1595	DNA-templated transcription, initiation
AL480_RS01550	COG1946	Acyl-CoA thioesterase
AL480_RS01570	COG0824	Thioesterase
AL480_RS01575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL480_RS01580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL480_RS01585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL480_RS01590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL480_RS01595	COG0268	Binds directly to 16S ribosomal RNA
AL480_RS01600	COG0728	peptidoglycan biosynthetic process
AL480_RS01605	COG0196	riboflavin kinase activity
AL480_RS01610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL480_RS01620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL480_RS01645	COG4206	TonB-dependent receptor
AL480_RS01665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL480_RS01705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL480_RS01710	COG1845	cytochrome c oxidase, subunit III
AL480_RS01715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL480_RS01730	COG0326	Molecular chaperone. Has ATPase activity
AL480_RS01750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL480_RS01765	COG0228	four-way junction DNA binding
AL480_RS01770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL480_RS01775	COG0336	Belongs to the RNA methyltransferase TrmD family
AL480_RS01780	COG0335	large ribosomal subunit rRNA binding
AL480_RS01800	COG0534	Mate efflux family protein
AL480_RS01820	COG0753	catalase activity
AL480_RS01830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL480_RS02025	COG2200	EAL domain
AL480_RS02160	COG1192	Involved in chromosome partitioning
AL480_RS02220	COG0666	response to abiotic stimulus
AL480_RS02230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL480_RS02265	COG0840	transmembrane signaling receptor activity
AL480_RS02285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS02305	COG0024	Methionine aminopeptidase
AL480_RS02330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL480_RS02355	COG1647	Serine aminopeptidase, S33
AL480_RS02380	COG2814	Major facilitator Superfamily
AL480_RS02385	COG3706	GGDEF domain
AL480_RS02410	COG0588	phosphoglycerate mutase activity
AL480_RS02415	COG3590	peptidase
AL480_RS02430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL480_RS02440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL480_RS02445	COG0745	RESPONSE REGULATOR receiver
AL480_RS02450	COG2205	protein histidine kinase activity
AL480_RS02455	COG4452	Inner membrane protein CreD
AL480_RS02470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL480_RS02475	COG0735	belongs to the Fur family
AL480_RS02515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL480_RS02560	COG5001	Diguanylate cyclase
AL480_RS02560	COG5002	protein histidine kinase activity
AL480_RS02570	COG1187	pseudouridine synthase activity
AL480_RS02580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL480_RS02605	COG1132	(ABC) transporter
AL480_RS02660	COG1695	Transcriptional regulator
AL480_RS02680	COG1981	membrane
AL480_RS02685	COG0825	malonyl-CoA metabolic process
AL480_RS02710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL480_RS02720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL480_RS02725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL480_RS02730	COG0750	zinc metalloprotease
AL480_RS02735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL480_RS02740	COG0575	Belongs to the CDS family
AL480_RS02745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL480_RS02750	COG0233	cytoplasmic translational termination
AL480_RS02755	COG0528	UMP kinase activity
AL480_RS02765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL480_RS02770	COG0052	Belongs to the universal ribosomal protein uS2 family
AL480_RS02790	COG3188	usher protein
AL480_RS02810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL480_RS02825	COG1393	Belongs to the ArsC family
AL480_RS02830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL480_RS02840	COG0367	asparagine synthase
AL480_RS02845	COG0475	glutathione-regulated potassium exporter activity
AL480_RS02880	COG1566	PFAM secretion protein HlyD family protein
AL480_RS02885	COG2814	Major facilitator Superfamily
AL480_RS02900	COG0583	DNA-binding transcription factor activity
AL480_RS02920	COG0557	exoribonuclease II activity
AL480_RS02930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL480_RS02940	COG1538	Outer membrane efflux protein
AL480_RS02945	COG1136	(ABC) transporter
AL480_RS02945	COG0577	efflux transmembrane transporter activity
AL480_RS02950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS02970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL480_RS02975	COG2259	Doxx family
AL480_RS02985	COG3220	belongs to the UPF0276 family
AL480_RS02995	COG0704	Plays a role in the regulation of phosphate uptake
AL480_RS03005	COG0581	inorganic phosphate transmembrane transporter activity
AL480_RS03010	COG0573	inorganic phosphate transmembrane transporter activity
AL480_RS03015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL480_RS03020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL480_RS03030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL480_RS03040	COG1024	Enoyl-CoA hydratase
AL480_RS03050	COG0494	nUDIX hydrolase
AL480_RS03070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL480_RS03070	COG0116	Belongs to the methyltransferase superfamily
AL480_RS03095	COG2733	membrane
AL480_RS03105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL480_RS03110	COG1012	belongs to the aldehyde dehydrogenase family
AL480_RS03120	COG0477	Major facilitator Superfamily
AL480_RS03125	COG2703	oxygen carrier activity
AL480_RS03145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL480_RS03150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL480_RS03155	COG0174	glutamine synthetase
AL480_RS03165	COG2072	flavoprotein involved in K transport
AL480_RS03170	COG3842	ATPase activity
AL480_RS03175	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL480_RS03180	COG1177	transmembrane transport
AL480_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
AL480_RS03200	COG4535	Mg2 and Co2 transporter CorC
AL480_RS03220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL480_RS03225	COG1702	phosphate starvation-inducible protein PhoH
AL480_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS03235	COG1131	(ABC) transporter
AL480_RS03240	COG0842	Transport permease protein
AL480_RS03245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL480_RS03260	COG0741	lytic transglycosylase activity
AL480_RS03265	COG0723	plastoquinol--plastocyanin reductase activity
AL480_RS03270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL480_RS03275	COG2857	Cytochrome c1
AL480_RS03280	COG0625	glutathione transferase activity
AL480_RS03285	COG2969	positive regulation of protein catabolic process
AL480_RS03320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL480_RS03330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL480_RS03345	COG1611	Belongs to the LOG family
AL480_RS03385	COG4970	Tfp pilus assembly protein FimT
AL480_RS03390	COG0556	nucleotide-excision repair
AL480_RS03425	COG3713	MltA-interacting MipA family protein
AL480_RS03445	COG0811	peptide transport
AL480_RS03460	COG1663	tetraacyldisaccharide 4'-kinase activity
AL480_RS03465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL480_RS03470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL480_RS03480	COG0322	excinuclease ABC activity
AL480_RS03515	COG1136	(ABC) transporter
AL480_RS03515	COG0577	efflux transmembrane transporter activity
AL480_RS03570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL480_RS03605	COG0583	DNA-binding transcription factor activity
AL480_RS03625	COG4977	sequence-specific DNA binding
AL480_RS03625	COG1917	Cupin 2, conserved barrel domain protein
AL480_RS03630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL480_RS03650	COG0348	domain, Protein
AL480_RS03665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL480_RS03770	COG0305	Participates in initiation and elongation during chromosome replication
AL480_RS03955	COG3772	lysozyme
AL480_RS04005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL480_RS04010	COG0069	glutamate synthase activity
AL480_RS04035	COG1054	Belongs to the UPF0176 family
AL480_RS04040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL480_RS04055	COG1253	flavin adenine dinucleotide binding
AL480_RS04075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL480_RS04090	COG0504	CTP synthase activity
AL480_RS04095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL480_RS04110	COG0148	phosphopyruvate hydratase activity
AL480_RS04115	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL480_RS04120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL480_RS04135	COG2840	Smr protein MutS2
AL480_RS04140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL480_RS04145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL480_RS04170	COG1534	Rna-binding protein
AL480_RS04175	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL480_RS04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL480_RS04195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL480_RS04200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL480_RS04205	COG1923	regulation of RNA biosynthetic process
AL480_RS04210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL480_RS04215	COG1546	Belongs to the CinA family
AL480_RS04220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL480_RS04225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL480_RS04230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL480_RS04235	COG2137	regulation of response to DNA damage stimulus
AL480_RS04240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL480_RS04245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL480_RS04295	COG3540	Alkaline phosphatase
AL480_RS04310	COG3258	Cytochrome c
AL480_RS04325	COG2223	nitrite transmembrane transporter activity
AL480_RS04340	COG1741	Belongs to the pirin family
AL480_RS04345	COG0583	DNA-binding transcription factor activity
AL480_RS04375	COG0352	thiamine-phosphate diphosphorylase activity
AL480_RS04375	COG0351	phosphomethylpyrimidine kinase
AL480_RS04390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL480_RS04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL480_RS04405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL480_RS04415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL480_RS04420	COG0477	Major facilitator Superfamily
AL480_RS04430	COG0617	tRNA 3'-terminal CCA addition
AL480_RS04435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL480_RS04440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL480_RS04445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL480_RS04455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL480_RS04460	COG0166	Belongs to the GPI family
AL480_RS04465	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL480_RS04475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL480_RS04480	COG0671	phosphoesterase, PA-phosphatase related
AL480_RS04490	COG0800	Aldolase
AL480_RS04495	COG0129	dihydroxy-acid dehydratase activity
AL480_RS04505	COG0837	glucose binding
AL480_RS04530	COG2009	succinate dehydrogenase
AL480_RS04535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL480_RS04540	COG1053	succinate dehydrogenase
AL480_RS04560	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL480_RS04575	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL480_RS04585	COG0552	protein localization to endoplasmic reticulum
AL480_RS04605	COG0742	ribosomal rna small subunit methyltransferase
AL480_RS04610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL480_RS04620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL480_RS04625	COG0405	Gamma-glutamyltransferase
AL480_RS04630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL480_RS04655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL480_RS04675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL480_RS04685	COG0415	Belongs to the DNA photolyase family
AL480_RS04690	COG2885	chlorophyll binding
AL480_RS04695	COG0583	DNA-binding transcription factor activity
AL480_RS04855	COG2974	May be involved in recombination
AL480_RS05195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL480_RS05205	COG2914	Belongs to the UPF0125 (RnfH) family
AL480_RS05210	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL480_RS05215	COG0735	belongs to the Fur family
AL480_RS05225	COG0583	DNA-binding transcription factor activity
AL480_RS05230	COG0497	DNA recombination
AL480_RS05235	COG1420	regulation of RNA biosynthetic process
AL480_RS05240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL480_RS05245	COG0443	Heat shock 70 kDa protein
AL480_RS05250	COG0484	heat shock protein binding
AL480_RS05255	COG2207	Transcriptional regulator
AL480_RS05260	COG2223	nitrite transmembrane transporter activity
AL480_RS05265	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL480_RS05270	COG1605	Chorismate mutase
AL480_RS05270	COG0287	Prephenate dehydrogenase
AL480_RS05280	COG1132	(ABC) transporter
AL480_RS05310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL480_RS05315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL480_RS05320	COG0343	queuine tRNA-ribosyltransferase activity
AL480_RS05325	COG1862	Preprotein translocase
AL480_RS05335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL480_RS05345	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL480_RS05355	COG2081	HI0933 family
AL480_RS05360	COG4681	YaeQ
AL480_RS05365	COG0564	pseudouridine synthase activity
AL480_RS05380	COG0625	glutathione transferase activity
AL480_RS05385	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL480_RS05390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL480_RS05395	COG0513	Belongs to the DEAD box helicase family
AL480_RS05405	COG0583	DNA-binding transcription factor activity
AL480_RS05410	COG0488	(ABC) transporter
AL480_RS05435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS05450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL480_RS05455	COG2957	Belongs to the agmatine deiminase family
AL480_RS05465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL480_RS05470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL480_RS05480	COG0776	regulation of translation
AL480_RS05490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL480_RS05495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL480_RS05505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL480_RS05510	COG0183	Belongs to the thiolase family
AL480_RS05515	COG1024	Enoyl-CoA hydratase
AL480_RS05515	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL480_RS05525	COG0105	UTP biosynthetic process
AL480_RS05530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL480_RS05540	COG1426	Protein conserved in bacteria
AL480_RS05540	COG1426	Protein conserved in bacteria
AL480_RS05545	COG2976	Protein conserved in bacteria
AL480_RS05550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL480_RS05555	COG1160	GTP binding
AL480_RS05580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL480_RS05585	COG0475	glutathione-regulated potassium exporter activity
AL480_RS05585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL480_RS05600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL480_RS05600	COG0519	Catalyzes the synthesis of GMP from XMP
AL480_RS05610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL480_RS05615	COG0732	type I restriction modification DNA specificity domain
AL480_RS05625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL480_RS05635	COG0583	DNA-binding transcription factor activity
AL480_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS05680	COG0640	Transcriptional regulator
AL480_RS05695	COG4716	Myosin-crossreactive antigen
AL480_RS05730	COG4206	TonB-dependent receptor
AL480_RS05735	COG0431	NADPH-dependent FMN reductase
AL480_RS05745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL480_RS05750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL480_RS05755	COG1473	amidohydrolase
AL480_RS05765	COG1126	abc transporter atp-binding protein
AL480_RS05770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL480_RS05790	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL480_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS05815	COG1309	transcriptional regulator
AL480_RS05830	COG0697	spore germination
AL480_RS05835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL480_RS05840	COG0167	dihydroorotate dehydrogenase activity
AL480_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS05860	COG1012	belongs to the aldehyde dehydrogenase family
AL480_RS05910	COG0745	RESPONSE REGULATOR receiver
AL480_RS05915	COG0784	Response regulator, receiver
AL480_RS05915	COG4191	Histidine kinase
AL480_RS05920	COG2205	protein histidine kinase activity
AL480_RS05920	COG3437	response regulator, receiver
AL480_RS05920	COG4999	Histidine kinase
AL480_RS05920	COG3850	Histidine kinase
AL480_RS05925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL480_RS05945	COG0640	Transcriptional regulator
AL480_RS05980	COG0527	aspartate kinase activity
AL480_RS05980	COG0460	homoserine dehydrogenase
AL480_RS05995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL480_RS06000	COG0124	histidyl-tRNA synthetase
AL480_RS06010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL480_RS06015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL480_RS06020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL480_RS06025	COG0131	Imidazoleglycerol-phosphate dehydratase
AL480_RS06025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL480_RS06030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL480_RS06035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL480_RS06040	COG0107	imidazoleglycerol-phosphate synthase activity
AL480_RS06045	COG0140	phosphoribosyl-ATP diphosphatase activity
AL480_RS06045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL480_RS06065	COG1446	asparaginase
AL480_RS06070	COG3142	Participates in the control of copper homeostasis
AL480_RS06080	COG2217	Heavy metal translocating P-type atpase
AL480_RS06085	COG0789	Transcriptional regulator
AL480_RS06105	COG3537	Alpha-1,2-mannosidase
AL480_RS06110	COG1609	Transcriptional regulator
AL480_RS06120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL480_RS06135	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AL480_RS06140	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL480_RS06145	COG0235	Class ii aldolase
AL480_RS06160	COG0531	amino acid
AL480_RS06165	COG0531	amino acid
AL480_RS06175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL480_RS06180	COG0277	FAD linked oxidase domain protein
AL480_RS06195	COG2205	protein histidine kinase activity
AL480_RS06200	COG0745	RESPONSE REGULATOR receiver
AL480_RS06210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS06225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL480_RS06270	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL480_RS06285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL480_RS06290	COG0505	Belongs to the CarA family
AL480_RS06295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL480_RS06300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL480_RS06315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL480_RS06320	COG4676	Protein conserved in bacteria
AL480_RS06330	COG3279	Response regulator of the LytR AlgR family
AL480_RS06345	COG1012	belongs to the aldehyde dehydrogenase family
AL480_RS06365	COG2205	protein histidine kinase activity
AL480_RS06365	COG2198	Histidine kinase
AL480_RS06365	COG0784	Response regulator, receiver
AL480_RS06370	COG1024	Enoyl-CoA hydratase
AL480_RS06375	COG0318	PFAM AMP-dependent synthetase and ligase
AL480_RS06380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AL480_RS06385	COG1012	belongs to the aldehyde dehydrogenase family
AL480_RS06390	COG1309	transcriptional regulator
AL480_RS06395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL480_RS06440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL480_RS06450	COG0840	transmembrane signaling receptor activity
AL480_RS06455	COG0840	transmembrane signaling receptor activity
AL480_RS06465	COG0835	chemotaxis
AL480_RS06470	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AL480_RS06475	COG0840	transmembrane signaling receptor activity
AL480_RS06485	COG0745	RESPONSE REGULATOR receiver
AL480_RS06495	COG0835	chemotaxis
AL480_RS06505	COG1360	Flagellar Motor Protein
AL480_RS06510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL480_RS06515	COG2198	Histidine kinase
AL480_RS06515	COG0784	Response regulator, receiver
AL480_RS06515	COG0643	Histidine kinase
AL480_RS06520	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL480_RS06545	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL480_RS06550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL480_RS06565	COG1987	bacterial-type flagellum assembly
AL480_RS06575	COG3190	flagellar
AL480_RS06625	COG1677	Flagellar hook-basal body complex protein FliE
AL480_RS06650	COG2197	response regulator
AL480_RS06670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL480_RS06680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL480_RS06710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL480_RS06720	COG4787	bacterial-type flagellum-dependent cell motility
AL480_RS06740	COG1815	bacterial-type flagellum-dependent cell motility
AL480_RS06745	COG0784	Response regulator, receiver
AL480_RS06745	COG0835	chemotaxis
AL480_RS06765	COG5002	protein histidine kinase activity
AL480_RS06800	COG2915	High frequency lysogenization protein hflD homolog
AL480_RS06805	COG0482	sulfurtransferase activity
AL480_RS06820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL480_RS06830	COG0542	response to heat
AL480_RS06860	COG0492	ferredoxin-NADP+ reductase activity
AL480_RS06865	COG1674	ftsk spoiiie
AL480_RS06880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL480_RS06900	COG2819	hydrolase of the alpha beta superfamily
AL480_RS06910	COG4558	Periplasmic binding protein
AL480_RS06915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL480_RS06920	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL480_RS06930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL480_RS06955	COG1136	(ABC) transporter
AL480_RS06955	COG0577	efflux transmembrane transporter activity
AL480_RS06970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL480_RS06985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL480_RS06995	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AL480_RS07010	COG1595	DNA-templated transcription, initiation
AL480_RS07030	COG0784	Response regulator, receiver
AL480_RS07035	COG4251	negative regulation of phosphorylation
AL480_RS07045	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AL480_RS07055	COG0454	-acetyltransferase
AL480_RS07055	COG0456	acetyltransferase
AL480_RS07060	COG2205	protein histidine kinase activity
AL480_RS07125	COG2217	Heavy metal translocating P-type atpase
AL480_RS07140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS07145	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS07160	COG0010	Belongs to the arginase family
AL480_RS07215	COG2132	Multicopper oxidase
AL480_RS07240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL480_RS07310	COG0583	DNA-binding transcription factor activity
AL480_RS07445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL480_RS07450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL480_RS07455	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AL480_RS07460	COG2080	2 iron, 2 sulfur cluster binding
AL480_RS07475	COG1309	transcriptional regulator
AL480_RS07490	COG4221	oxidoreductase activity
AL480_RS07535	COG3685	Protein conserved in bacteria
AL480_RS07560	COG3546	catalase activity
AL480_RS07565	COG3685	Protein conserved in bacteria
AL480_RS07590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL480_RS07610	COG1063	alcohol dehydrogenase
AL480_RS07640	COG1609	Transcriptional regulator
AL480_RS07645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL480_RS07645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL480_RS07650	COG1105	Belongs to the carbohydrate kinase PfkB family
AL480_RS07655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL480_RS07655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL480_RS07670	COG1733	regulation of RNA biosynthetic process
AL480_RS07675	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL480_RS07690	COG0738	Major facilitator superfamily
AL480_RS07695	COG1609	Transcriptional regulator
AL480_RS07700	COG1472	Belongs to the glycosyl hydrolase 3 family
AL480_RS07715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL480_RS07730	COG2828	Protein conserved in bacteria
AL480_RS07735	COG0583	DNA-binding transcription factor activity
AL480_RS07765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL480_RS07770	COG0583	DNA-binding transcription factor activity
AL480_RS07785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL480_RS07815	COG2186	Transcriptional regulator
AL480_RS07835	COG2271	Major facilitator Superfamily
AL480_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS07850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL480_RS07880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL480_RS07900	COG0583	DNA-binding transcription factor activity
AL480_RS07925	COG2204	response regulator
AL480_RS08025	COG0708	Exodeoxyribonuclease III
AL480_RS08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL480_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS08055	COG0577	efflux transmembrane transporter activity
AL480_RS08055	COG1136	(ABC) transporter
AL480_RS08060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS08075	COG2205	protein histidine kinase activity
AL480_RS08085	COG3214	Protein conserved in bacteria
AL480_RS08095	COG4774	siderophore transport
AL480_RS08105	COG0596	Alpha beta hydrolase
AL480_RS08145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL480_RS08150	COG1285	pathogenesis
AL480_RS08155	COG4191	Histidine kinase
AL480_RS08160	COG4566	intracellular signal transduction
AL480_RS08240	COG0477	Major facilitator Superfamily
AL480_RS08280	COG0583	DNA-binding transcription factor activity
AL480_RS08285	COG0656	L-ascorbic acid biosynthetic process
AL480_RS08305	COG0583	DNA-binding transcription factor activity
AL480_RS08310	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS08335	COG0642	Histidine kinase
AL480_RS08340	COG3537	Alpha-1,2-mannosidase
AL480_RS08360	COG0477	Major facilitator Superfamily
AL480_RS08425	COG1335	isochorismatase
AL480_RS08430	COG1335	isochorismatase
AL480_RS08460	COG0811	peptide transport
AL480_RS08600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL480_RS08605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL480_RS08615	COG0840	transmembrane signaling receptor activity
AL480_RS08620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL480_RS08625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL480_RS08630	COG4149	molybdate abc transporter
AL480_RS08635	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL480_RS08640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL480_RS08650	COG0746	molybdenum cofactor guanylyltransferase activity
AL480_RS08650	COG0315	cyclic pyranopterin monophosphate synthase activity
AL480_RS08655	COG0314	molybdopterin synthase activity
AL480_RS08665	COG0303	'Molybdopterin
AL480_RS08670	COG0315	cyclic pyranopterin monophosphate synthase activity
AL480_RS08670	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL480_RS08675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL480_RS08700	COG2207	Transcriptional regulator
AL480_RS08740	COG2205	protein histidine kinase activity
AL480_RS08750	COG2194	sulfuric ester hydrolase activity
AL480_RS08770	COG2885	chlorophyll binding
AL480_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS08795	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL480_RS08795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL480_RS08800	COG1535	isochorismatase
AL480_RS08800	COG3433	isochorismatase activity
AL480_RS08805	COG3433	isochorismatase activity
AL480_RS08805	COG1535	isochorismatase
AL480_RS08810	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL480_RS08815	COG1169	isochorismate synthase
AL480_RS08825	COG2409	Drug exporters of the RND superfamily
AL480_RS08830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL480_RS08890	COG1914	H( )-stimulated, divalent metal cation uptake system
AL480_RS08905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL480_RS08910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL480_RS08920	COG4206	TonB-dependent receptor
AL480_RS08925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL480_RS08960	COG0583	DNA-binding transcription factor activity
AL480_RS08970	COG4772	TonB-dependent receptor
AL480_RS08995	COG2226	methyltransferase
AL480_RS09040	COG4964	Belongs to the GSP D family
AL480_RS09095	COG2814	Major facilitator Superfamily
AL480_RS09105	COG1228	amidohydrolase
AL480_RS09115	COG1335	isochorismatase
AL480_RS09130	COG3850	Histidine kinase
AL480_RS09135	COG2197	response regulator
AL480_RS09140	COG2814	Major facilitator Superfamily
AL480_RS09150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AL480_RS09160	COG0583	DNA-binding transcription factor activity
AL480_RS09175	COG3161	chorismate lyase activity
AL480_RS09210	COG0277	FAD linked oxidase domain protein
AL480_RS09215	COG1304	FMN binding
AL480_RS09220	COG2186	Transcriptional regulator
AL480_RS09230	COG1285	pathogenesis
AL480_RS09260	COG2814	Major facilitator Superfamily
AL480_RS09320	COG0587	DNA-directed DNA polymerase activity
AL480_RS09335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL480_RS09340	COG0519	Catalyzes the synthesis of GMP from XMP
AL480_RS09340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL480_RS09355	COG1595	DNA-templated transcription, initiation
AL480_RS09365	COG1629	transport
AL480_RS09365	COG4206	TonB-dependent receptor
AL480_RS09395	COG0531	amino acid
AL480_RS09410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL480_RS09420	COG0789	Transcriptional regulator
AL480_RS09505	COG5002	protein histidine kinase activity
AL480_RS09505	COG5001	Diguanylate cyclase
AL480_RS09505	COG3447	MASE1 domain protein
AL480_RS09510	COG2183	response to ionizing radiation
AL480_RS09525	COG1983	PspC domain protein
AL480_RS09535	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL480_RS09550	COG1073	alpha beta
AL480_RS09550	COG2226	methyltransferase
AL480_RS09555	COG0534	Mate efflux family protein
AL480_RS09575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL480_RS09585	COG0668	transmembrane transport
AL480_RS09590	COG1902	pentaerythritol trinitrate reductase activity
AL480_RS09610	COG1733	regulation of RNA biosynthetic process
AL480_RS09615	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL480_RS09620	COG0456	acetyltransferase
AL480_RS09690	COG3702	type iv secretory pathway
AL480_RS09710	COG2948	multi-organism process
AL480_RS09720	COG3736	Type IV secretory pathway, component VirB8
AL480_RS09730	COG3505	Type IV secretory pathway VirD4
AL480_RS09745	COG2814	Major facilitator Superfamily
AL480_RS09750	COG0789	Transcriptional regulator
AL480_RS09780	COG0784	Response regulator, receiver
AL480_RS09780	COG4191	Histidine kinase
AL480_RS09795	COG4774	siderophore transport
AL480_RS09815	COG1733	regulation of RNA biosynthetic process
AL480_RS09820	COG0604	alcohol dehydrogenase
AL480_RS09830	COG0210	DNA helicase
AL480_RS09845	COG0583	DNA-binding transcription factor activity
AL480_RS09850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL480_RS09860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL480_RS09875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL480_RS09880	COG1605	Chorismate mutase
AL480_RS09880	COG0077	Prephenate dehydratase
AL480_RS09885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL480_RS09935	COG1228	amidohydrolase
AL480_RS09950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL480_RS10000	COG2957	Belongs to the agmatine deiminase family
AL480_RS10005	COG0583	DNA-binding transcription factor activity
AL480_RS10060	COG4993	Dehydrogenase
AL480_RS10070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AL480_RS10080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL480_RS10090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL480_RS10095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL480_RS10110	COG0359	binds to the 23S rRNA
AL480_RS10115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL480_RS10120	COG0360	Binds together with S18 to 16S ribosomal RNA
AL480_RS10130	COG0316	Belongs to the HesB IscA family
AL480_RS10135	COG0017	Asparaginyl-tRNA synthetase
AL480_RS10155	COG0288	reversible hydration of carbon dioxide
AL480_RS10165	COG3844	kynureninase activity
AL480_RS10170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL480_RS10175	COG2925	Exonuclease
AL480_RS10205	COG2902	Dehydrogenase
AL480_RS10215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS10235	COG1960	acyl-CoA dehydrogenase activity
AL480_RS10240	COG2226	methyltransferase
AL480_RS10250	COG0646	methionine synthase
AL480_RS10250	COG1410	methionine synthase
AL480_RS10265	COG2900	Belongs to the SlyX family
AL480_RS10280	COG0386	Belongs to the glutathione peroxidase family
AL480_RS10290	COG1725	Transcriptional regulator
AL480_RS10295	COG1131	(ABC) transporter
AL480_RS10320	COG0114	fumarate hydratase activity
AL480_RS10330	COG2850	peptidyl-arginine hydroxylation
AL480_RS10340	COG0567	Dehydrogenase, E1 component
AL480_RS10365	COG3540	Alkaline phosphatase
AL480_RS10375	COG0305	Participates in initiation and elongation during chromosome replication
AL480_RS10395	COG0625	glutathione transferase activity
AL480_RS10415	COG0084	hydrolase, TatD family'
AL480_RS10420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL480_RS10455	COG3415	Transposase
AL480_RS10455	COG2801	Transposase and inactivated derivatives
AL480_RS10460	COG0625	glutathione transferase activity
AL480_RS10475	COG1595	DNA-templated transcription, initiation
AL480_RS10480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL480_RS10495	COG0386	Belongs to the glutathione peroxidase family
AL480_RS10500	COG0339	signal peptide processing
AL480_RS10505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL480_RS10525	COG0705	Rhomboid family
AL480_RS10530	COG3104	oligopeptide transport
AL480_RS10540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL480_RS10545	COG4290	ribonuclease
AL480_RS10560	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL480_RS10560	COG0316	Belongs to the HesB IscA family
AL480_RS10565	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL480_RS10575	COG0428	transporter
AL480_RS10585	COG1530	ribonuclease E activity
AL480_RS10600	COG0395	ABC-type sugar transport system, permease component
AL480_RS10630	COG0271	Belongs to the BolA IbaG family
AL480_RS10635	COG2350	Protein conserved in bacteria
AL480_RS10640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL480_RS10645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL480_RS10650	COG1187	pseudouridine synthase activity
AL480_RS10660	COG2814	Major facilitator Superfamily
AL480_RS10685	COG0436	Aminotransferase
AL480_RS10690	COG4133	protoheme IX ABC transporter activity
AL480_RS10710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL480_RS10725	COG3088	subunit of a heme lyase
AL480_RS10725	COG4235	cytochrome complex assembly
AL480_RS10735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL480_RS10745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL480_RS10750	COG4988	ABC transporter
AL480_RS10760	COG1294	oxidase, subunit
AL480_RS10790	COG0726	polysaccharide deacetylase
AL480_RS10790	COG1649	PFAM Uncharacterised BCR, COG1649
AL480_RS10795	COG1215	transferase activity, transferring glycosyl groups
AL480_RS10805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL480_RS10820	COG0165	Argininosuccinate lyase
AL480_RS10825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL480_RS10835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL480_RS10840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL480_RS10845	COG0137	argininosuccinate synthase activity
AL480_RS10850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL480_RS10865	COG2166	iron-sulfur cluster assembly
AL480_RS10885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL480_RS10905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL480_RS10910	COG0402	S-adenosylhomocysteine deaminase activity
AL480_RS10915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL480_RS10920	COG1509	lysine 2,3-aminomutase activity
AL480_RS10925	COG3300	MHYT domain
AL480_RS10925	COG5001	Diguanylate cyclase
AL480_RS10945	COG0501	Belongs to the peptidase M48B family
AL480_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS10975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL480_RS10980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL480_RS10985	COG0802	atpase or kinase
AL480_RS10990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL480_RS10990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL480_RS10995	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL480_RS11000	COG1570	exodeoxyribonuclease VII activity
AL480_RS11010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL480_RS11030	COG4771	TonB-dependent receptor
AL480_RS11050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL480_RS11050	COG2169	Transcriptional regulator
AL480_RS11055	COG2130	NADP-dependent
AL480_RS11080	COG1960	acyl-CoA dehydrogenase activity
AL480_RS11090	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL480_RS11125	COG2076	Multidrug Resistance protein
AL480_RS11130	COG5487	UPF0391 membrane protein
AL480_RS11135	COG1280	lysine exporter protein (LysE YggA)
AL480_RS11140	COG0740	serine-type endopeptidase activity
AL480_RS11155	COG1794	racemase activity, acting on amino acids and derivatives
AL480_RS11190	COG0776	regulation of translation
AL480_RS11195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL480_RS11195	COG0072	phenylalanine-tRNA ligase activity
AL480_RS11200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL480_RS11205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL480_RS11210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL480_RS11215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL480_RS11220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL480_RS11250	COG1185	polyribonucleotide nucleotidyltransferase activity
AL480_RS11255	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL480_RS11265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL480_RS11270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL480_RS11275	COG0195	Participates in both transcription termination and antitermination
AL480_RS11280	COG0779	Required for maturation of 30S ribosomal subunits
AL480_RS11295	COG1007	ATP synthesis coupled electron transport
AL480_RS11310	COG0713	ATP synthesis coupled electron transport
AL480_RS11320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL480_RS11325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL480_RS11340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL480_RS11345	COG0649	NAD binding
AL480_RS11350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL480_RS11355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL480_RS11360	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL480_RS11375	COG0149	triose-phosphate isomerase activity
AL480_RS11385	COG3083	sulfuric ester hydrolase activity
AL480_RS11390	COG0438	transferase activity, transferring glycosyl groups
AL480_RS11395	COG0726	polysaccharide deacetylase
AL480_RS11400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL480_RS11405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL480_RS11410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL480_RS11415	COG0159	tryptophan synthase activity
AL480_RS11425	COG0133	tryptophan synthase activity
AL480_RS11435	COG0135	phosphoribosylanthranilate isomerase activity
AL480_RS11440	COG0101	tRNA pseudouridine synthase activity
AL480_RS11455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL480_RS11460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL480_RS11465	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL480_RS11470	COG2890	protein-(glutamine-N5) methyltransferase activity
AL480_RS11475	COG1999	signal sequence binding
AL480_RS11480	COG0688	phosphatidylethanolamine metabolic process
AL480_RS11495	COG0433	COG0433 Predicted ATPase
AL480_RS11500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL480_RS11510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL480_RS11515	COG0412	Dienelactone hydrolase
AL480_RS11525	COG0717	Belongs to the dCTP deaminase family
AL480_RS11530	COG0489	protein tyrosine kinase activity
AL480_RS11535	COG4771	TonB-dependent receptor
AL480_RS11540	COG4771	TonB-dependent receptor
AL480_RS11550	COG4771	TonB-dependent receptor
AL480_RS11555	COG3590	peptidase
AL480_RS11590	COG0697	spore germination
AL480_RS11600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL480_RS11605	COG2311	Membrane
AL480_RS11610	COG1047	Peptidyl-prolyl cis-trans
AL480_RS11615	COG0791	NLP P60 protein
AL480_RS11620	COG0791	NLP P60 protein
AL480_RS11625	COG1301	dicarboxylic acid transport
AL480_RS11645	COG1722	exodeoxyribonuclease VII activity
AL480_RS11650	COG0142	geranyltranstransferase activity
AL480_RS11660	COG0312	modulator of DNA gyrase
AL480_RS11665	COG3028	Belongs to the UPF0307 family
AL480_RS11670	COG0312	modulator of DNA gyrase
AL480_RS11690	COG2968	Membrane
AL480_RS11700	COG4771	TonB-dependent receptor
AL480_RS11715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL480_RS11725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL480_RS11740	COG0495	leucyl-tRNA aminoacylation
AL480_RS11750	COG3118	belongs to the thioredoxin family
AL480_RS11760	COG4251	negative regulation of phosphorylation
AL480_RS11760	COG5001	Diguanylate cyclase
AL480_RS11760	COG3706	GGDEF domain
AL480_RS11760	COG2203	Gaf domain
AL480_RS11780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL480_RS11790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL480_RS11795	COG0346	lactoylglutathione lyase activity
AL480_RS11810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL480_RS11810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL480_RS11820	COG2878	Part of a membrane complex involved in electron transport
AL480_RS11830	COG0251	oxidation-reduction process
AL480_RS11835	COG0392	lysyltransferase activity
AL480_RS11835	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AL480_RS11865	COG2824	Alkylphosphonate utilization operon protein PhnA
AL480_RS11870	COG0443	Heat shock 70 kDa protein
AL480_RS11910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL480_RS11915	COG3122	Protein conserved in bacteria
AL480_RS11920	COG1451	nucleotide metabolic process
AL480_RS11930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL480_RS11950	COG0183	Belongs to the thiolase family
AL480_RS11965	COG1960	acyl-CoA dehydrogenase activity
AL480_RS11975	COG1793	dna ligase
AL480_RS11980	COG1201	RNA secondary structure unwinding
AL480_RS11995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL480_RS12000	COG1278	Cold shock
AL480_RS12005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL480_RS12010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AL480_RS12015	COG1472	Belongs to the glycosyl hydrolase 3 family
AL480_RS12020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AL480_RS12025	COG2954	triphosphatase activity
AL480_RS12030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL480_RS12035	COG0745	RESPONSE REGULATOR receiver
AL480_RS12040	COG1381	Involved in DNA repair and RecF pathway recombination
AL480_RS12045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL480_RS12060	COG0681	Belongs to the peptidase S26 family
AL480_RS12065	COG0481	GTPase activity
AL480_RS12070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL480_RS12090	COG1741	Belongs to the pirin family
AL480_RS12095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL480_RS12105	COG1741	Belongs to the pirin family
AL480_RS12115	COG1966	Carbon starvation protein
AL480_RS12120	COG2879	small protein
AL480_RS12135	COG2205	protein histidine kinase activity
AL480_RS12175	COG2814	Major facilitator Superfamily
AL480_RS12180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL480_RS12180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL480_RS12190	COG1113	amino acid transport
AL480_RS12195	COG2207	Transcriptional regulator
AL480_RS12195	COG1917	Cupin 2, conserved barrel domain protein
AL480_RS12200	COG0753	catalase activity
AL480_RS12230	COG1376	ErfK ybiS ycfS ynhG family protein
AL480_RS12235	COG0739	heme binding
AL480_RS12245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL480_RS12255	COG0330	HflC and HflK could
AL480_RS12260	COG0330	HflC and HflK could
AL480_RS12265	COG0604	alcohol dehydrogenase
AL480_RS12280	COG0678	peroxiredoxin activity
AL480_RS12290	COG4953	penicillin-binding protein 1C
AL480_RS12295	COG2373	Large extracellular alpha-helical protein
AL480_RS12300	COG2079	MmgE PrpD family protein
AL480_RS12305	COG2828	Protein conserved in bacteria
AL480_RS12335	COG3829	transcription factor binding
AL480_RS12350	COG0259	pyridoxamine-phosphate oxidase activity
AL480_RS12365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL480_RS12385	COG0477	Major facilitator Superfamily
AL480_RS12405	COG3038	cytochrome b561
AL480_RS12420	COG1760	l-serine dehydratase
AL480_RS12425	COG2267	carboxylic ester hydrolase activity
AL480_RS12430	COG0460	homoserine dehydrogenase
AL480_RS12430	COG0527	aspartate kinase activity
AL480_RS12435	COG0626	cystathionine gamma-synthase activity
AL480_RS12440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL480_RS12445	COG0739	heme binding
AL480_RS12450	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL480_RS12455	COG1272	protein, Hemolysin III
AL480_RS12470	COG0463	Glycosyl transferase, family 2
AL480_RS12475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL480_RS12480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL480_RS12490	COG4206	TonB-dependent receptor
AL480_RS12495	COG1309	transcriptional regulator
AL480_RS12505	COG1960	acyl-CoA dehydrogenase activity
AL480_RS12535	COG0583	DNA-binding transcription factor activity
AL480_RS12545	COG0509	glycine decarboxylation via glycine cleavage system
AL480_RS12550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL480_RS12560	COG0330	HflC and HflK could
AL480_RS12575	COG3956	TIGRFAM MazG family protein
AL480_RS12585	COG0494	nUDIX hydrolase
AL480_RS12595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL480_RS12610	COG2198	Histidine kinase
AL480_RS12610	COG0784	Response regulator, receiver
AL480_RS12610	COG0643	Histidine kinase
AL480_RS12615	COG0840	transmembrane signaling receptor activity
AL480_RS12620	COG0835	chemotaxis
AL480_RS12635	COG0189	ligase activity
AL480_RS12650	COG1199	ATP-dependent helicase activity
AL480_RS12660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL480_RS12665	COG1215	transferase activity, transferring glycosyl groups
AL480_RS12680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL480_RS12690	COG1643	Atp-dependent helicase
AL480_RS12695	COG0783	Belongs to the Dps family
AL480_RS12700	COG0514	ATP-dependent DNA helicase (RecQ)
AL480_RS13000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL480_RS13005	COG0602	queuosine metabolic process
AL480_RS13015	COG2885	chlorophyll binding
AL480_RS13020	COG0823	Involved in the tonB-independent uptake of proteins
AL480_RS13035	COG0811	peptide transport
AL480_RS13040	COG0824	Thioesterase
AL480_RS13045	COG2255	four-way junction helicase activity
AL480_RS13055	COG0632	four-way junction helicase activity
AL480_RS13060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL480_RS13065	COG0217	transcriptional regulatory protein
AL480_RS13085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL480_RS13115	COG0488	(ABC) transporter
AL480_RS13125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL480_RS13125	COG4651	solute:proton antiporter activity
AL480_RS13140	COG0745	RESPONSE REGULATOR receiver
AL480_RS13145	COG2205	protein histidine kinase activity
AL480_RS13155	COG0542	response to heat
AL480_RS13180	COG0028	Belongs to the TPP enzyme family
AL480_RS13210	COG3387	PFAM Glycoside hydrolase 15-related
AL480_RS13215	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AL480_RS13220	COG3011	Protein conserved in bacteria
AL480_RS13235	COG0564	pseudouridine synthase activity
AL480_RS13240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL480_RS13255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL480_RS13255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL480_RS13265	COG0045	succinate-CoA ligase (ADP-forming) activity
AL480_RS13300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AL480_RS13320	COG0745	RESPONSE REGULATOR receiver
AL480_RS13335	COG0189	ligase activity
AL480_RS13360	COG3240	lipase activity
AL480_RS13360	COG4625	pathogenesis
AL480_RS13370	COG2022	thiamine diphosphate biosynthetic process
AL480_RS13375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL480_RS13380	COG0471	metal ion transport
AL480_RS13380	COG3273	potassium ion transport
AL480_RS13400	COG1970	mechanosensitive ion channel activity
AL480_RS13415	COG1115	amino acid carrier protein
AL480_RS13425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS13430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS13460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL480_RS13470	COG3588	fructose-bisphosphate aldolase
AL480_RS13475	COG0469	pyruvate kinase activity
AL480_RS13485	COG0126	phosphoglycerate kinase activity
AL480_RS13500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL480_RS13545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL480_RS13550	COG1301	dicarboxylic acid transport
AL480_RS13580	COG0714	Associated with various cellular activities
AL480_RS13610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL480_RS13625	COG5295	Hep Hag repeat protein
AL480_RS13665	COG0254	rRNA binding
AL480_RS13675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL480_RS13685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL480_RS13690	COG1758	RNA polymerase activity
AL480_RS13700	COG0243	molybdopterin cofactor binding
AL480_RS13700	COG3383	formate dehydrogenase (NAD+) activity
AL480_RS13705	COG0243	molybdopterin cofactor binding
AL480_RS13705	COG3383	formate dehydrogenase (NAD+) activity
AL480_RS13710	COG0437	4 iron, 4 sulfur cluster binding
AL480_RS13715	COG2864	formate dehydrogenase
AL480_RS13725	COG1921	L-seryl-tRNASec selenium transferase activity
AL480_RS13730	COG3276	selenocysteine insertion sequence binding
AL480_RS13740	COG0709	Synthesizes selenophosphate from selenide and ATP
AL480_RS13745	COG1561	YicC-like family, N-terminal region
AL480_RS13750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL480_RS13755	COG0346	lactoylglutathione lyase activity
AL480_RS13765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL480_RS13780	COG0006	proline dipeptidase activity
AL480_RS13785	COG0006	proline dipeptidase activity
AL480_RS13790	COG3079	Belongs to the UPF0149 family
AL480_RS13810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL480_RS13820	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL480_RS13830	COG2912	Transglutaminase-like superfamily
AL480_RS13835	COG1773	rubredoxin
AL480_RS13845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL480_RS13850	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL480_RS13860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL480_RS13865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL480_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS13895	COG0671	phosphoesterase, PA-phosphatase related
AL480_RS13910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL480_RS13915	COG0563	adenylate kinase activity
AL480_RS13935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AL480_RS13945	COG0848	biopolymer transport protein
AL480_RS13955	COG2832	Protein of unknown function (DUF454)
AL480_RS13990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL480_RS14015	COG0745	RESPONSE REGULATOR receiver
AL480_RS14025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL480_RS14030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL480_RS14035	COG0405	Gamma-glutamyltransferase
AL480_RS14040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL480_RS14060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL480_RS14065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL480_RS14080	COG0473	3-isopropylmalate dehydrogenase activity
AL480_RS14095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS14100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS14110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL480_RS14115	COG1538	Outer membrane efflux protein
AL480_RS14120	COG0531	amino acid
AL480_RS14125	COG1519	Transferase
AL480_RS14130	COG1560	Kdo2-lipid A biosynthetic process
AL480_RS14170	COG1301	dicarboxylic acid transport
AL480_RS14180	COG4191	Histidine kinase
AL480_RS14195	COG0642	Histidine kinase
AL480_RS14210	COG2851	Citrate transporter
AL480_RS14215	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS14240	COG1162	GTPase activity
AL480_RS14245	COG0436	Aminotransferase
AL480_RS14265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL480_RS14280	COG1228	amidohydrolase
AL480_RS14285	COG0804	urea catabolic process
AL480_RS14295	COG1307	EDD domain protein, DegV family
AL480_RS14335	COG2203	Gaf domain
AL480_RS14335	COG3706	GGDEF domain
AL480_RS14335	COG4251	negative regulation of phosphorylation
AL480_RS14335	COG5001	Diguanylate cyclase
AL480_RS14340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AL480_RS14350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL480_RS14365	COG1902	pentaerythritol trinitrate reductase activity
AL480_RS14390	COG0583	DNA-binding transcription factor activity
AL480_RS14395	COG1064	alcohol dehydrogenase
AL480_RS14415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL480_RS14420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL480_RS14430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL480_RS14435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL480_RS14450	COG1522	sequence-specific DNA binding
AL480_RS14460	COG4773	Receptor
AL480_RS14465	COG4206	TonB-dependent receptor
AL480_RS14485	COG0617	tRNA 3'-terminal CCA addition
AL480_RS14520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL480_RS14525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL480_RS14530	COG1609	Transcriptional regulator
AL480_RS14540	COG0837	glucose binding
AL480_RS14550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AL480_RS14570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL480_RS14580	COG4191	Histidine kinase
AL480_RS14585	COG0784	Response regulator, receiver
AL480_RS14590	COG4251	negative regulation of phosphorylation
AL480_RS14595	COG2823	Periplasmic or secreted lipoprotein
AL480_RS14600	COG0673	inositol 2-dehydrogenase activity
AL480_RS14610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AL480_RS14630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL480_RS14640	COG2921	Belongs to the UPF0250 family
AL480_RS14650	COG1686	Belongs to the peptidase S11 family
AL480_RS14655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL480_RS14660	COG2951	lytic endotransglycosylase activity
AL480_RS14670	COG0772	Belongs to the SEDS family
AL480_RS14675	COG0772	Belongs to the SEDS family
AL480_RS14690	COG1792	Involved in formation and maintenance of cell shape
AL480_RS14695	COG1077	Cell shape determining protein MreB Mrl
AL480_RS14700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL480_RS14715	COG0308	aminopeptidase N
AL480_RS14720	COG2226	methyltransferase
AL480_RS14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS14765	COG0673	inositol 2-dehydrogenase activity
AL480_RS14775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL480_RS14790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL480_RS14800	COG2832	Protein of unknown function (DUF454)
AL480_RS14810	COG0436	Aminotransferase
AL480_RS14815	COG1505	serine-type exopeptidase activity
AL480_RS14840	COG0697	spore germination
AL480_RS14845	COG1666	GTP binding
AL480_RS14860	COG0339	signal peptide processing
AL480_RS14870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL480_RS14890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL480_RS14900	COG1136	(ABC) transporter
AL480_RS14905	COG0577	efflux transmembrane transporter activity
AL480_RS14905	COG1136	(ABC) transporter
AL480_RS14910	COG0577	efflux transmembrane transporter activity
AL480_RS14920	COG2204	response regulator
AL480_RS14925	COG4191	Histidine kinase
AL480_RS14935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL480_RS14945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL480_RS14950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL480_RS14955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL480_RS14960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL480_RS14965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL480_RS14970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL480_RS14980	COG0356	it plays a direct role in the translocation of protons across the membrane
AL480_RS14995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL480_RS15000	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL480_RS15020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL480_RS15045	COG0181	hydroxymethylbilane synthase activity
AL480_RS15060	COG2972	Histidine kinase
AL480_RS15060	COG0745	RESPONSE REGULATOR receiver
AL480_RS15080	COG4771	TonB-dependent receptor
AL480_RS15110	COG0477	Major facilitator Superfamily
AL480_RS15155	COG4206	TonB-dependent receptor
AL480_RS15175	COG0625	glutathione transferase activity
AL480_RS15190	COG2259	Doxx family
AL480_RS15315	COG0582	viral genome integration into host DNA
AL480_RS15330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL480_RS15335	COG1490	D-aminoacyl-tRNA deacylase activity
AL480_RS15345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL480_RS15380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL480_RS15380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL480_RS15385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL480_RS15390	COG0242	peptide deformylase activity
AL480_RS15400	COG0758	DNA mediated transformation
AL480_RS15405	COG2922	Belongs to the Smg family
AL480_RS15415	COG1714	RDD family
AL480_RS15420	COG1754	DNA topoisomerase type I activity
AL480_RS15420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL480_RS15425	COG0009	L-threonylcarbamoyladenylate synthase
AL480_RS15440	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS15450	COG0616	signal peptide processing
AL480_RS15455	COG0534	Mate efflux family protein
AL480_RS15470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL480_RS15475	COG0625	glutathione transferase activity
AL480_RS15485	COG1252	NADH dehydrogenase
AL480_RS15505	COG2860	membrane
AL480_RS15515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL480_RS15535	COG1846	Transcriptional regulator
AL480_RS15565	COG0459	protein refolding
AL480_RS15570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL480_RS15575	COG2356	endonuclease I
AL480_RS15580	COG1324	tolerance protein
AL480_RS15590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL480_RS15625	COG4585	Histidine kinase
AL480_RS15645	COG0583	DNA-binding transcription factor activity
AL480_RS15655	COG1785	Belongs to the alkaline phosphatase family
AL480_RS15660	COG1686	Belongs to the peptidase S11 family
AL480_RS15670	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL480_RS15680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL480_RS15690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL480_RS15695	COG0511	ligase activity, forming carbon-carbon bonds
AL480_RS15700	COG0439	Biotin carboxylase
AL480_RS15715	COG2264	protein methyltransferase activity
AL480_RS15725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL480_RS15730	COG4589	Belongs to the CDS family
AL480_RS15735	COG0204	Acyl-transferase
AL480_RS15745	COG0671	phosphoesterase, PA-phosphatase related
AL480_RS15745	COG2453	phosphatase
AL480_RS15750	COG2267	carboxylic ester hydrolase activity
AL480_RS15755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL480_RS15760	COG0138	bifunctional purine biosynthesis protein purh
AL480_RS15765	COG0151	Belongs to the GarS family
AL480_RS15780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL480_RS15785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL480_RS15790	COG2201	protein-glutamate methylesterase activity
AL480_RS15795	COG2177	Part of the ABC transporter FtsEX involved in
AL480_RS15800	COG2884	Cell division ATP-binding protein ftsE
AL480_RS15815	COG3118	belongs to the thioredoxin family
AL480_RS15820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL480_RS15825	COG3706	GGDEF domain
AL480_RS15835	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL480_RS15875	COG1652	LysM domain
AL480_RS15880	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL480_RS15880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL480_RS15885	COG1473	amidohydrolase
AL480_RS15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS15895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS15900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS15905	COG1289	transmembrane transporter activity
AL480_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS15915	COG2814	Major facilitator Superfamily
AL480_RS15945	COG0316	Belongs to the HesB IscA family
AL480_RS15985	COG1051	belongs to the nudix hydrolase family
AL480_RS16000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL480_RS16005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL480_RS16010	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL480_RS16020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL480_RS16025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL480_RS16030	COG0730	response to heat
AL480_RS16040	COG0134	indole-3-glycerol-phosphate synthase activity
AL480_RS16045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL480_RS16070	COG1597	lipid kinase activity
AL480_RS16085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL480_RS16090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL480_RS16100	COG2111	Na H antiporter
AL480_RS16100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL480_RS16105	COG1006	Multisubunit Na H antiporter MnhC subunit
AL480_RS16110	COG0651	ATP synthesis coupled electron transport
AL480_RS16115	COG1863	multisubunit Na H antiporter MnhE subunit
AL480_RS16120	COG2212	antiporter activity
AL480_RS16125	COG1320	monovalent cation:proton antiporter activity
AL480_RS16130	COG0530	calcium, potassium:sodium antiporter activity
AL480_RS16145	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL480_RS16160	COG4804	nuclease activity
AL480_RS16175	COG3104	oligopeptide transport
AL480_RS16180	COG3483	tryptophan 2,3-dioxygenase activity
AL480_RS16210	COG2378	regulation of single-species biofilm formation
AL480_RS16225	COG2354	Protein conserved in bacteria
AL480_RS16230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL480_RS16235	COG1368	sulfuric ester hydrolase activity
AL480_RS16245	COG3264	Mechanosensitive ion channel
AL480_RS16245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL480_RS16260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL480_RS16260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL480_RS16295	COG1166	arginine decarboxylase activity
AL480_RS16300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL480_RS16320	COG2960	long-chain fatty acid transporting porin activity
AL480_RS16340	COG3209	COG3209 Rhs family protein
AL480_RS16425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL480_RS16425	COG3453	Protein conserved in bacteria
AL480_RS16440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL480_RS16460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL480_RS16475	COG0431	NADPH-dependent FMN reductase
AL480_RS16490	COG0798	PFAM Bile acid sodium symporter
AL480_RS16505	COG0659	secondary active sulfate transmembrane transporter activity
AL480_RS16510	COG0604	alcohol dehydrogenase
AL480_RS16515	COG0583	DNA-binding transcription factor activity
AL480_RS16520	COG4221	oxidoreductase activity
AL480_RS16575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL480_RS16575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL480_RS16590	COG1902	pentaerythritol trinitrate reductase activity
AL480_RS16650	COG0402	S-adenosylhomocysteine deaminase activity
AL480_RS16705	COG0561	phosphatase activity
AL480_RS16710	COG3932	Exopolysaccharide synthesis, ExoD
AL480_RS16740	COG1999	signal sequence binding
AL480_RS16745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL480_RS16750	COG1845	cytochrome c oxidase, subunit III
AL480_RS16760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL480_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL480_RS16780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL480_RS16785	COG1104	cysteine desulfurase activity
AL480_RS16835	COG2031	fatty acid transporter
AL480_RS16880	COG0673	inositol 2-dehydrogenase activity
AL480_RS16890	COG1501	Belongs to the glycosyl hydrolase 31 family
AL480_RS16895	COG2222	sugar isomerase
AL480_RS16900	COG1940	carbohydrate kinase activity
AL480_RS16910	COG1349	DNA-binding transcription factor activity
AL480_RS16915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL480_RS16920	COG2814	Major facilitator Superfamily
AL480_RS16935	COG1040	competence protein
AL480_RS16955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL480_RS16960	COG0156	8-amino-7-oxononanoate synthase activity
AL480_RS16965	COG2267	carboxylic ester hydrolase activity
AL480_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS16985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL480_RS17010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL480_RS17015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL480_RS17020	COG2205	protein histidine kinase activity
AL480_RS17025	COG0745	RESPONSE REGULATOR receiver
AL480_RS17030	COG3541	Predicted nucleotidyltransferase
AL480_RS17035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL480_RS17060	COG0714	Associated with various cellular activities
AL480_RS17075	COG0754	glutathionylspermidine amidase activity
AL480_RS17085	COG0129	dihydroxy-acid dehydratase activity
AL480_RS17090	COG1199	ATP-dependent helicase activity
AL480_RS17100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL480_RS17120	COG3781	membrane
AL480_RS17150	COG0625	glutathione transferase activity
AL480_RS17170	COG2207	Transcriptional regulator
AL480_RS17185	COG4555	ABC transporter
AL480_RS17215	COG0543	2 iron, 2 sulfur cluster binding
AL480_RS17215	COG0633	Ferredoxin
AL480_RS17220	COG1131	(ABC) transporter
AL480_RS17225	COG0842	Transport permease protein
AL480_RS17235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL480_RS17245	COG0084	hydrolase, TatD family'
AL480_RS17255	COG1643	Atp-dependent helicase
AL480_RS17265	COG1187	pseudouridine synthase activity
AL480_RS17280	COG0667	Aldo Keto reductase
AL480_RS17295	COG1690	Belongs to the RtcB family
AL480_RS17310	COG0840	transmembrane signaling receptor activity
AL480_RS17315	COG0583	DNA-binding transcription factor activity
AL480_RS17320	COG2814	Major facilitator Superfamily
AL480_RS17325	COG0656	L-ascorbic acid biosynthetic process
AL480_RS17330	COG2267	carboxylic ester hydrolase activity
AL480_RS17335	COG0393	Putative heavy-metal-binding
AL480_RS17340	COG1042	CoA-binding domain protein
AL480_RS17340	COG0045	succinate-CoA ligase (ADP-forming) activity
AL480_RS17340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL480_RS17345	COG2239	Acts as a magnesium transporter
AL480_RS17360	COG3177	Filamentation induced by cAMP protein fic
AL480_RS17360	COG0666	response to abiotic stimulus
AL480_RS17365	COG3100	YcgL domain-containing protein
AL480_RS17375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL480_RS17380	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS17420	COG2986	histidine ammonia-lyase
AL480_RS17430	COG0463	Glycosyl transferase, family 2
AL480_RS17445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL480_RS17450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL480_RS17465	COG1294	oxidase, subunit
AL480_RS17470	COG1271	oxidase subunit
AL480_RS17480	COG1595	DNA-templated transcription, initiation
AL480_RS17520	COG0408	coproporphyrinogen oxidase activity
AL480_RS17530	COG2323	membrane
AL480_RS17545	COG0589	response to stress
AL480_RS17565	COG0210	DNA helicase
AL480_RS17575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL480_RS17580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL480_RS17585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL480_RS17590	COG1819	glycosyl
AL480_RS17605	COG0251	oxidation-reduction process
AL480_RS17640	COG0463	Glycosyl transferase, family 2
AL480_RS17655	COG1475	DNA binding
AL480_RS17660	COG1192	Involved in chromosome partitioning
AL480_RS17665	COG0357	Ribosomal RNA small subunit methyltransferase G
AL480_RS17670	COG2091	lysine biosynthetic process via aminoadipic acid
AL480_RS17710	COG1971	Probably functions as a manganese efflux pump
AL480_RS17715	COG2205	protein histidine kinase activity
AL480_RS17715	COG0784	Response regulator, receiver
AL480_RS17730	COG2911	Protein conserved in bacteria
AL480_RS17735	COG0729	surface antigen
AL480_RS17745	COG0752	glycyl-tRNA synthetase alpha subunit
AL480_RS17750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL480_RS17755	COG0519	Catalyzes the synthesis of GMP from XMP
AL480_RS17755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL480_RS17765	COG0805	protein transport
AL480_RS17775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL480_RS17785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL480_RS17790	COG0596	Alpha beta hydrolase
AL480_RS17790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL480_RS17795	COG0840	transmembrane signaling receptor activity
AL480_RS17850	COG3135	benzoate transporter
AL480_RS17865	COG2951	lytic endotransglycosylase activity
AL480_RS17870	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL480_RS17875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL480_RS17880	COG3706	GGDEF domain
AL480_RS17910	COG0302	gtp cyclohydrolase
AL480_RS17935	COG1289	transmembrane transporter activity
AL480_RS17950	COG1074	ATP-dependent DNA helicase activity
AL480_RS17955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL480_RS17960	COG1127	ABC transporter
AL480_RS17965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL480_RS17970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL480_RS17985	COG2853	Lipoprotein
AL480_RS17990	COG0386	Belongs to the glutathione peroxidase family
AL480_RS18000	COG1322	Protein conserved in bacteria
AL480_RS18015	COG0583	DNA-binding transcription factor activity
AL480_RS18035	COG0667	Aldo Keto reductase
AL480_RS18040	COG0531	amino acid
AL480_RS18050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL480_RS18055	COG0861	Integral membrane protein TerC family
AL480_RS18065	COG0584	glycerophosphoryl diester phosphodiesterase
AL480_RS18090	COG0706	membrane insertase activity
AL480_RS18095	COG0594	ribonuclease P activity
AL480_RS18100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL480_RS18105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL480_RS18115	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL480_RS18120	COG0187	DNA topoisomerase II activity
AL480_RS18125	COG1266	CAAX protease self-immunity
AL480_RS18130	COG0501	Belongs to the peptidase M48B family
AL480_RS18185	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL480_RS18195	COG4772	TonB-dependent receptor
AL480_RS18230	COG0800	Aldolase
AL480_RS18245	COG3186	Phenylalanine-4-hydroxylase
AL480_RS18250	COG1522	sequence-specific DNA binding
AL480_RS18260	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL480_RS18270	COG4771	TonB-dependent receptor
AL480_RS18290	COG1119	ATPase activity
AL480_RS18305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL480_RS18310	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AL480_RS18335	COG0210	DNA helicase
AL480_RS18345	COG3132	Protein of unknown function, DUF480
AL480_RS18350	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AL480_RS18355	COG0284	orotidine-5'-phosphate decarboxylase activity
AL480_RS18365	COG2937	Belongs to the GPAT DAPAT family
AL480_RS18375	COG0037	tRNA processing
AL480_RS18380	COG2974	May be involved in recombination
AL480_RS18390	COG1803	Methylglyoxal synthase
AL480_RS18395	COG2205	protein histidine kinase activity
AL480_RS18395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL480_RS18400	COG0493	'glutamate synthase
AL480_RS18405	COG0067	glutamate synthase
AL480_RS18405	COG0070	glutamate synthase
AL480_RS18405	COG0069	glutamate synthase activity
AL480_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
AL480_RS18440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL480_RS18475	COG1205	dead DEAH box helicase
AL480_RS18475	COG1111	helicase
AL480_RS18510	COG0714	Associated with various cellular activities
AL480_RS18530	COG0312	modulator of DNA gyrase
AL480_RS18550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL480_RS18570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL480_RS18595	COG1881	PFAM PEBP family protein
AL480_RS18610	COG1968	undecaprenyl-diphosphatase activity
AL480_RS18615	COG0174	glutamine synthetase
AL480_RS18620	COG0347	Belongs to the P(II) protein family
AL480_RS18625	COG0004	ammonium transporteR
AL480_RS18630	COG2831	hemolysin activation secretion protein
AL480_RS18635	COG3210	domain, Protein
AL480_RS18665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL480_RS18680	COG3852	Histidine kinase
AL480_RS18685	COG2204	response regulator
AL480_RS18690	COG2032	superoxide dismutase activity
AL480_RS18695	COG2032	superoxide dismutase activity
AL480_RS18710	COG0183	Belongs to the thiolase family
AL480_RS18745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL480_RS18750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL480_RS18770	COG0798	PFAM Bile acid sodium symporter
AL480_RS18785	COG0431	NADPH-dependent FMN reductase
AL480_RS18925	COG2837	iron assimilation
AL480_RS18965	COG2197	response regulator
AL480_RS18970	COG2205	protein histidine kinase activity
AL480_RS18970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL480_RS18975	COG3474	cytochrome
AL480_RS18985	COG1960	acyl-CoA dehydrogenase activity
AL480_RS18995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL480_RS19005	COG0612	Peptidase, M16
AL480_RS19015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL480_RS19020	COG0596	Alpha beta hydrolase
AL480_RS19030	COG0318	PFAM AMP-dependent synthetase and ligase
AL480_RS19035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL480_RS19045	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL480_RS19060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL480_RS19090	COG0339	signal peptide processing
AL480_RS19110	COG0681	Belongs to the peptidase S26 family
AL480_RS19115	COG2814	Major facilitator Superfamily
AL480_RS19120	COG3415	Transposase
AL480_RS19120	COG2801	Transposase and inactivated derivatives
AL480_RS19125	COG0583	DNA-binding transcription factor activity
AL480_RS19130	COG0583	DNA-binding transcription factor activity
AL480_RS19135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL480_RS19140	COG2224	Isocitrate lyase
AL480_RS19145	COG3706	GGDEF domain
AL480_RS19170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL480_RS19175	COG1960	acyl-CoA dehydrogenase activity
AL480_RS19195	COG0697	spore germination
AL480_RS19205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL480_RS19215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL480_RS19225	COG1280	lysine exporter protein (LysE YggA)
AL480_RS19230	COG1607	acyl-coa hydrolase
AL480_RS19240	COG1902	pentaerythritol trinitrate reductase activity
AL480_RS19255	COG1335	isochorismatase
AL480_RS19260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL480_RS19270	COG1051	belongs to the nudix hydrolase family
AL480_RS19270	COG1056	cytidyltransferase-related domain
AL480_RS19275	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL480_RS19280	COG1396	sequence-specific DNA binding
AL480_RS19280	COG3800	Transcriptional regulator
AL480_RS19290	COG1960	acyl-CoA dehydrogenase activity
AL480_RS19295	COG1024	Enoyl-CoA hydratase
AL480_RS19300	COG1024	Enoyl-CoA hydratase
AL480_RS19310	COG1764	response to oxidative stress
AL480_RS19335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL480_RS19365	COG3228	Belongs to the MtfA family
AL480_RS19375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL480_RS19375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL480_RS19380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL480_RS19395	COG3657	addiction module killer protein
AL480_RS19435	COG3237	CsbD-like
AL480_RS19445	COG0180	Tryptophanyl-tRNA synthetase
AL480_RS19470	COG0477	Major facilitator Superfamily
AL480_RS19475	COG0697	spore germination
AL480_RS19490	COG0577	efflux transmembrane transporter activity
AL480_RS19490	COG1136	(ABC) transporter
AL480_RS19500	COG1136	(ABC) transporter
AL480_RS19520	COG4585	Histidine kinase
AL480_RS19525	COG2197	response regulator
AL480_RS19540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL480_RS19550	COG0628	permease
AL480_RS19570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL480_RS19585	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL480_RS19615	COG2814	Major facilitator Superfamily
AL480_RS19620	COG0583	DNA-binding transcription factor activity
AL480_RS19625	COG4807	Protein conserved in bacteria
AL480_RS19635	COG4221	oxidoreductase activity
AL480_RS19645	COG0018	arginyl-trna synthetase
AL480_RS19650	COG2003	Belongs to the UPF0758 family
AL480_RS19655	COG2197	response regulator
AL480_RS19660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL480_RS19665	COG0756	dUTP diphosphatase activity
AL480_RS19680	COG2205	protein histidine kinase activity
AL480_RS19690	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL480_RS19695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AL480_RS19710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL480_RS19715	COG0708	Exodeoxyribonuclease III
AL480_RS19720	COG2223	nitrite transmembrane transporter activity
AL480_RS19735	COG0739	heme binding
AL480_RS19740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL480_RS19800	COG2234	aminopeptidase activity
AL480_RS19810	COG4942	peptidase
AL480_RS19815	COG0793	Belongs to the peptidase S41A family
AL480_RS19825	COG2067	long-chain fatty acid transport protein
AL480_RS19855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL480_RS19900	COG0109	protoheme IX farnesyltransferase activity
AL480_RS19920	COG0358	DNA primase activity
AL480_RS19925	COG1295	ribonuclease BN
AL480_RS19940	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL480_RS19950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL480_RS19955	COG0668	transmembrane transport
AL480_RS19970	COG2133	pyrroloquinoline quinone binding
AL480_RS19975	COG4682	membrane
AL480_RS19985	COG0531	amino acid
AL480_RS19995	COG1737	Transcriptional regulator
AL480_RS20000	COG4948	Mandelate Racemase Muconate Lactonizing
AL480_RS20050	COG5383	Protein conserved in bacteria
AL480_RS20060	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL480_RS20065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL480_RS20095	COG0778	Nitroreductase
AL480_RS20100	COG2353	YceI-like domain
AL480_RS20115	COG2375	cellular response to nickel ion
AL480_RS20210	COG2267	carboxylic ester hydrolase activity
AL480_RS20265	COG0488	(ABC) transporter
AL480_RS20270	COG0583	DNA-binding transcription factor activity
AL480_RS20280	COG2814	Major facilitator Superfamily
AL480_RS20285	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL480_RS20290	COG1113	amino acid transport
AL480_RS20295	COG0741	lytic transglycosylase activity
AL480_RS20320	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL480_RS20330	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL480_RS20335	COG4941	Belongs to the sigma-70 factor family
AL480_RS20365	COG3275	phosphorelay sensor kinase activity
AL480_RS20370	COG3279	Response regulator of the LytR AlgR family
AL480_RS20390	COG1309	transcriptional regulator
AL480_RS20405	COG3590	peptidase
AL480_RS20410	COG5001	Diguanylate cyclase
AL480_RS20415	COG0583	DNA-binding transcription factor activity
AL480_RS20425	COG3384	dioxygenase
AL480_RS20430	COG0025	NhaP-type Na H and K H
AL480_RS20455	COG1360	Flagellar Motor Protein
AL480_RS20485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL480_RS20500	COG5002	protein histidine kinase activity
AL480_RS20515	COG2813	Specifically methylates the guanine in position
AL480_RS20520	COG1187	pseudouridine synthase activity
AL480_RS20525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL480_RS20535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL480_RS20540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL480_RS20560	COG0583	DNA-binding transcription factor activity
AL480_RS20565	COG2226	methyltransferase
AL480_RS20590	COG1956	GAF domain-containing protein
AL480_RS20595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL480_RS20600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL480_RS20605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL480_RS20610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL480_RS20610	COG0785	Cytochrome C biogenesis protein
AL480_RS20615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL480_RS20620	COG0745	RESPONSE REGULATOR receiver
AL480_RS20625	COG2205	protein histidine kinase activity
AL480_RS20630	COG2205	protein histidine kinase activity
AL480_RS20635	COG0745	RESPONSE REGULATOR receiver
AL480_RS20640	COG0367	asparagine synthase
AL480_RS20650	COG0720	synthase
AL480_RS20665	COG0513	Belongs to the DEAD box helicase family
AL480_RS20675	COG0625	glutathione transferase activity
AL480_RS20680	COG1573	uracil-dna glycosylase
AL480_RS20715	COG0626	cystathionine gamma-synthase activity
AL480_RS20735	COG1216	Glycosyl transferase, family 2
AL480_RS20735	COG0438	transferase activity, transferring glycosyl groups
AL480_RS20775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL480_RS20815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL480_RS20820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL480_RS20880	COG1127	ABC transporter
AL480_RS20885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL480_RS20900	COG0442	prolyl-tRNA aminoacylation
AL480_RS20915	COG1183	phosphatidylcholine synthase activity
AL480_RS20925	COG0456	acetyltransferase
AL480_RS20935	COG0525	valine-tRNA ligase activity
AL480_RS20945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL480_RS20955	COG0795	lipopolysaccharide-transporting ATPase activity
AL480_RS20965	COG4974	Belongs to the 'phage' integrase family
AL480_RS20970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL480_RS20980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL480_RS20980	COG0047	phosphoribosylformylglycinamidine synthase activity
AL480_RS20985	COG5295	Hep Hag repeat protein
AL480_RS20990	COG1404	Belongs to the peptidase S8 family
AL480_RS20995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL480_RS21000	COG1459	type II secretion system
AL480_RS21005	COG2165	general secretion pathway protein
AL480_RS21010	COG4970	Tfp pilus assembly protein FimT
AL480_RS21015	COG2165	general secretion pathway protein
AL480_RS21020	COG4795	General secretion pathway protein
AL480_RS21025	COG3156	type II secretion system protein K
AL480_RS21030	COG3166	PFAM Fimbrial assembly family protein
AL480_RS21045	COG1450	Type ii and iii secretion system protein
AL480_RS21070	COG3539	Fimbrial protein
AL480_RS21100	COG2194	sulfuric ester hydrolase activity
AL480_RS21125	COG3118	belongs to the thioredoxin family
AL480_RS21125	COG0457	Tetratricopeptide repeat
AL480_RS21130	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL480_RS21135	COG2252	PERMEase
AL480_RS21140	COG0488	(ABC) transporter
AL480_RS21150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL480_RS21170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL480_RS21175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL480_RS21175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL480_RS21205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL480_RS21210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL480_RS21220	COG3152	Membrane
AL480_RS21230	COG2755	lipolytic protein G-D-S-L family
AL480_RS21230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL480_RS21235	COG0277	FAD linked oxidase domain protein
AL480_RS21240	COG1988	membrane-bound metal-dependent
AL480_RS21280	COG2001	Belongs to the MraZ family
AL480_RS21285	COG0275	rRNA processing
AL480_RS21290	COG3116	cell division
AL480_RS21305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL480_RS21325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL480_RS21330	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL480_RS21335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL480_RS21345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL480_RS21350	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL480_RS21360	COG0739	heme binding
AL480_RS21365	COG0653	protein targeting
AL480_RS21370	COG0494	nUDIX hydrolase
AL480_RS21380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL480_RS21385	COG2267	carboxylic ester hydrolase activity
AL480_RS21390	COG3275	phosphorelay sensor kinase activity
AL480_RS21395	COG3279	Response regulator of the LytR AlgR family
AL480_RS21415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL480_RS21420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL480_RS21435	COG1607	acyl-coa hydrolase
AL480_RS21440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL480_RS21460	COG4106	trans-aconitate 2-methyltransferase activity
AL480_RS21465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL480_RS21475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL480_RS21480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL480_RS21485	COG0667	Aldo Keto reductase
AL480_RS21495	COG4771	TonB-dependent receptor
AL480_RS21510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL480_RS21515	COG4181	ATPase activity
AL480_RS21530	COG0642	Histidine kinase
AL480_RS21540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL480_RS21545	COG0861	Integral membrane protein TerC family
AL480_RS21550	COG2814	Major facilitator Superfamily
AL480_RS21555	COG1704	LemA family
AL480_RS21570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL480_RS21575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL480_RS21585	COG3738	Protein conserved in bacteria
AL480_RS21590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL480_RS21595	COG2967	ApaG domain
AL480_RS21600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL480_RS21605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL480_RS21610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL480_RS21615	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL480_RS21625	COG2096	Adenosyltransferase
AL480_RS21635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL480_RS21640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL480_RS21645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL480_RS21650	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AL480_RS21670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL480_RS21680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL480_RS21690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL480_RS21695	COG0583	DNA-binding transcription factor activity
AL480_RS21700	COG3634	alkyl hydroperoxide reductase activity
AL480_RS21740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL480_RS21740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL480_RS21755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL480_RS21795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL480_RS21800	COG1404	Belongs to the peptidase S8 family
AL480_RS21820	COG1295	ribonuclease BN
AL480_RS21825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL480_RS21840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL480_RS21845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL480_RS21860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL480_RS21870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL480_RS21875	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL480_RS21880	COG0193	aminoacyl-tRNA hydrolase activity
AL480_RS21885	COG0012	GTP binding
AL480_RS21890	COG4206	TonB-dependent receptor
AL480_RS21895	COG4242	Belongs to the peptidase S51 family
AL480_RS21920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL480_RS21935	COG0250	Participates in transcription elongation, termination and antitermination
AL480_RS21940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL480_RS21945	COG0081	regulation of translation
AL480_RS21955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL480_RS21960	COG0222	ribosome binding
AL480_RS21965	COG0085	RNA polymerase activity
AL480_RS21970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL480_RS21975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL480_RS21980	COG0049	tRNA binding
AL480_RS21985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL480_RS21990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL480_RS21995	COG0051	transcription antitermination factor activity, RNA binding
AL480_RS22000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL480_RS22005	COG0088	Forms part of the polypeptide exit tunnel
AL480_RS22010	COG0089	rRNA binding
AL480_RS22015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL480_RS22020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL480_RS22025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL480_RS22030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL480_RS22035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL480_RS22040	COG0255	Belongs to the universal ribosomal protein uL29 family
AL480_RS22045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL480_RS22050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL480_RS22055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL480_RS22060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL480_RS22065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL480_RS22075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL480_RS22080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL480_RS22085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL480_RS22090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL480_RS22095	COG1841	ribosomal large subunit assembly
AL480_RS22100	COG0200	Binds to the 23S rRNA
AL480_RS22105	COG0201	protein transport
AL480_RS22110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL480_RS22115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL480_RS22120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL480_RS22125	COG0202	RNA polymerase activity
AL480_RS22130	COG0203	ribosomal protein L17
AL480_RS22145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AL480_RS22160	COG0154	amidase activity
AL480_RS22175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL480_RS22180	COG0039	L-malate dehydrogenase activity
AL480_RS22185	COG0564	pseudouridine synthase activity
AL480_RS22190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL480_RS22205	COG0625	glutathione transferase activity
AL480_RS22215	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL480_RS22215	COG1902	pentaerythritol trinitrate reductase activity
AL480_RS22220	COG2364	Membrane
AL480_RS22225	COG0604	alcohol dehydrogenase
AL480_RS22240	COG1187	pseudouridine synthase activity
AL480_RS22260	COG1063	alcohol dehydrogenase
AL480_RS22270	COG0406	alpha-ribazole phosphatase activity
AL480_RS22275	COG0285	dihydrofolate synthase activity
AL480_RS22295	COG2833	Protein of unknown function (DUF455)
AL480_RS22305	COG3291	Pkd domain containing protein
AL480_RS22310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL480_RS22320	COG0438	transferase activity, transferring glycosyl groups
AL480_RS22330	COG0248	Ppx GppA phosphatase
AL480_RS22335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL480_RS22350	COG4783	chaperone-mediated protein folding
AL480_RS22365	COG0473	3-isopropylmalate dehydrogenase activity
AL480_RS22430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL480_RS22470	COG0592	DNA-directed DNA polymerase activity
AL480_RS22485	COG2204	response regulator
AL480_RS22630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL480_RS22630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL480_RS22700	COG0544	peptidyl-prolyl cis-trans isomerase activity