locus-tag	class	description
G6Z48_RS00005	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G6Z48_RS00015	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G6Z48_RS00025	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
G6Z48_RS00035	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G6Z48_RS00045	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G6Z48_RS00055	ENOG4108K5H	permease YjgP YjgQ family protein
G6Z48_RS00070	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G6Z48_RS00075	ENOG4105T95	Thiol disulfide interChange protein
G6Z48_RS00085	ENOG4108ETH	Formylglycinamide ribotide synthetase
G6Z48_RS00095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G6Z48_RS00100	ENOG4107QHF	type ii secretion system protein e
G6Z48_RS00105	ENOG4105D7Q	type ii secretion system
G6Z48_RS00115	ENOG4105WMT	general secretion pathway protein h
G6Z48_RS00125	ENOG41069G9	General secretion pathway protein J
G6Z48_RS00130	ENOG4105UV2	general secretion pathway protein K
G6Z48_RS00135	ENOG41090VX	general secretion pathway protein L
G6Z48_RS00140	ENOG410678M	general secretion pathway protein M
G6Z48_RS00150	ENOG4105GVR	general secretion pathway protein D
G6Z48_RS00175	ENOG4105X0I	Fimbrial
G6Z48_RS00195	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G6Z48_RS00205	ENOG410802X	bacteriophage n4 adsorption protein b
G6Z48_RS00220	ENOG4105C7N	Xanthine uracil vitamin C permease
G6Z48_RS00225	ENOG4105C5H	ABC transporter
G6Z48_RS00235	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G6Z48_RS00255	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G6Z48_RS00260	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G6Z48_RS00290	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G6Z48_RS00295	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G6Z48_RS00300	ENOG4107YIM	Involved in the transcription termination process (By similarity)
G6Z48_RS00305	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G6Z48_RS00310	ENOG4105GQR	Chaperone
G6Z48_RS00325	ENOG4105CW0	outer membrane usher protein
G6Z48_RS00335	ENOG4105EXC	Acyl-transferase
G6Z48_RS00340	ENOG4105CQB	FAD linked oxidase domain protein
G6Z48_RS00345	ENOG4105S2T	inner membrane protein YbcI
G6Z48_RS00380	ENOG4108V6E	Cell division protein mraZ
G6Z48_RS00385	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G6Z48_RS00390	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G6Z48_RS00395	ENOG4105CJN	penicillin-binding protein
G6Z48_RS00400	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G6Z48_RS00405	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G6Z48_RS00425	ENOG4105DFU	Cell wall formation (By similarity)
G6Z48_RS00430	ENOG4105CPF	Cell wall formation (By similarity)
G6Z48_RS00435	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G6Z48_RS00440	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G6Z48_RS00445	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G6Z48_RS00450	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6Z48_RS00460	ENOG4105DR5	peptidase
G6Z48_RS00465	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G6Z48_RS00470	ENOG4105M6F	mutator MutT protein
G6Z48_RS00480	ENOG4105SYT	Methylenetetrahydrofolate reductase
G6Z48_RS00485	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G6Z48_RS00490	ENOG4108HRK	Histidine kinase
G6Z48_RS00495	ENOG4105DY9	regulatoR
G6Z48_RS00515	ENOG4108Z66	YbaK ebsC protein
G6Z48_RS00520	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G6Z48_RS00530	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
G6Z48_RS00535	ENOG4108S4H	thioesterase Superfamily protein
G6Z48_RS00540	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G6Z48_RS00570	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
G6Z48_RS00575	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G6Z48_RS00585	ENOG4105EXG	Transcriptional regulator
G6Z48_RS00595	ENOG4108RVA	ribokinase
G6Z48_RS00600	ENOG4105D9N	nucleoside
G6Z48_RS00605	ENOG4105CPC	Aldo Keto reductase
G6Z48_RS00615	ENOG4107ENK	receptor
G6Z48_RS00635	ENOG4105CV6	ABC transporter, permease
G6Z48_RS00640	ENOG4108I0Y	(ABC) transporter
G6Z48_RS00645	ENOG4108UJV	acyl-CoA thioesterase i
G6Z48_RS00655	ENOG4105DHQ	Histidine kinase
G6Z48_RS00665	ENOG41080IJ	Diacylglycerol kinase
G6Z48_RS00670	ENOG4105EE5	Membrane protein terC
G6Z48_RS00675	ENOG4105F27	Major Facilitator
G6Z48_RS00680	ENOG4108V0P	LemA family
G6Z48_RS00695	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G6Z48_RS00700	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G6Z48_RS00710	ENOG4108XC3	NADH ubiquinone oxidoreductase
G6Z48_RS00720	ENOG4105NWN	ApaG protein
G6Z48_RS00730	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G6Z48_RS00735	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G6Z48_RS00740	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G6Z48_RS00745	ENOG4105DGU	Histone deacetylase
G6Z48_RS00750	ENOG4108WBT	adenosyltransferase
G6Z48_RS00760	ENOG4105D0A	hydroxylase
G6Z48_RS00770	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G6Z48_RS00775	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
G6Z48_RS00795	ENOG4105CX6	glutaminyL-tRNA synthetase
G6Z48_RS00805	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6Z48_RS00820	ENOG4105NXH	GreA GreB family elongation factor
G6Z48_RS00825	ENOG4105C5Q	Transcriptional regulator
G6Z48_RS00870	ENOG4105C2M	dna polymerase I
G6Z48_RS00885	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G6Z48_RS00905	ENOG4105W8H	transhydrogenase (subunit alpha
G6Z48_RS00910	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G6Z48_RS00925	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G6Z48_RS00930	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G6Z48_RS00945	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G6Z48_RS00950	ENOG4107S2Z	UPF0761 membrane protein
G6Z48_RS00955	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6Z48_RS00960	ENOG4105CSR	polyphosphate kinase 2
G6Z48_RS00970	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G6Z48_RS00975	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G6Z48_RS00980	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
G6Z48_RS00990	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G6Z48_RS01000	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G6Z48_RS01005	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G6Z48_RS01010	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G6Z48_RS01015	ENOG4105C3G	gtp-binding protein
G6Z48_RS01020	ENOG4106AS2	Outer membrane autotransporter
G6Z48_RS01025	ENOG41068CG	regulatoR
G6Z48_RS01030	ENOG4105BZU	Histidine kinase
G6Z48_RS01035	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
G6Z48_RS01040	ENOG4105BZU	Histidine kinase
G6Z48_RS01045	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS01055	ENOG4105D44	asparaginase
G6Z48_RS01075	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G6Z48_RS01085	ENOG4105PM1	preprotein translocase subunit SecE
G6Z48_RS01090	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G6Z48_RS01095	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G6Z48_RS01100	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G6Z48_RS01105	ENOG4108VZM	50s ribosomal protein L10
G6Z48_RS01110	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G6Z48_RS01115	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6Z48_RS01120	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6Z48_RS01125	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G6Z48_RS01130	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G6Z48_RS01135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G6Z48_RS01140	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G6Z48_RS01145	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G6Z48_RS01150	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G6Z48_RS01155	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G6Z48_RS01160	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G6Z48_RS01165	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6Z48_RS01170	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G6Z48_RS01175	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G6Z48_RS01180	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G6Z48_RS01185	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G6Z48_RS01190	ENOG41083MP	50s ribosomal protein l29
G6Z48_RS01195	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G6Z48_RS01200	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G6Z48_RS01205	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G6Z48_RS01210	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6Z48_RS01215	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G6Z48_RS01220	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G6Z48_RS01225	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G6Z48_RS01230	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G6Z48_RS01235	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G6Z48_RS01240	ENOG41087MT	50S ribosomal protein L30
G6Z48_RS01245	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G6Z48_RS01250	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G6Z48_RS01255	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6Z48_RS01260	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G6Z48_RS01265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G6Z48_RS01270	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6Z48_RS01275	ENOG4108ZT0	50S ribosomal protein l17
G6Z48_RS01280	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G6Z48_RS01290	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
G6Z48_RS01300	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G6Z48_RS01310	ENOG4105CI3	gtp-binding protein typa
G6Z48_RS01315	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
G6Z48_RS01320	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G6Z48_RS01325	ENOG4105D3G	Pseudouridine synthase
G6Z48_RS01330	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G6Z48_RS01345	ENOG4108K3A	Glutathione S-transferase
G6Z48_RS01355	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6Z48_RS01360	ENOG4108VW9	Membrane
G6Z48_RS01365	ENOG4105CIS	alcohol dehydrogenase
G6Z48_RS01370	ENOG4105CDV	Ompa motb domain protein
G6Z48_RS01380	ENOG4105FE9	pseudouridine synthase
G6Z48_RS01390	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G6Z48_RS01400	ENOG4105CPQ	Dehydrogenase
G6Z48_RS01410	ENOG4105CVJ	phosphoglycerate mutase
G6Z48_RS01415	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G6Z48_RS01430	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G6Z48_RS01435	ENOG4105ED9	Protein of unknown function (DUF455)
G6Z48_RS01445	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
G6Z48_RS01450	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
G6Z48_RS01460	ENOG4105BZF	Glycosyl transferase (Group 1
G6Z48_RS01465	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS01475	ENOG4105C9X	ppx gppa phosphatase
G6Z48_RS01480	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G6Z48_RS01485	ENOG4105BZU	Histidine kinase
G6Z48_RS01490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6Z48_RS01495	ENOG4105ERG	peptidase m48, ste24p
G6Z48_RS01500	ENOG4105VW4	glutaredoxin 3
G6Z48_RS01510	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G6Z48_RS01595	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G6Z48_RS01610	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6Z48_RS01625	ENOG4105KUS	lysozyme
G6Z48_RS01770	ENOG4105C2M	dna polymerase I
G6Z48_RS01855	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G6Z48_RS01860	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G6Z48_RS01865	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G6Z48_RS01905	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G6Z48_RS01910	ENOG41068JE	domain protein
G6Z48_RS01915	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G6Z48_RS01925	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G6Z48_RS01930	ENOG4107RZZ	dna polymerase iii epsilon subunit
G6Z48_RS01935	ENOG4108ZF3	Phosphatase
G6Z48_RS01955	ENOG4105DKP	glycosyl transferase, family 9
G6Z48_RS01960	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
G6Z48_RS01965	ENOG4107UV6	ribonuclease Z
G6Z48_RS01980	ENOG4105KPY	Small multidrug resistance protein
G6Z48_RS02015	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G6Z48_RS02020	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G6Z48_RS02030	ENOG4105K59	histidine triad (HIT) protein
G6Z48_RS02040	ENOG4105F8C	transglutaminase domain-containing protein
G6Z48_RS02050	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G6Z48_RS02065	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G6Z48_RS02070	ENOG4105VGS	50s ribosomal protein l32
G6Z48_RS02075	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G6Z48_RS02085	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G6Z48_RS02090	ENOG4105CHR	reductase
G6Z48_RS02100	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G6Z48_RS02110	ENOG4105HHA	aminodeoxychorismate lyase
G6Z48_RS02115	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G6Z48_RS02120	ENOG4107QRG	dna polymerase iii
G6Z48_RS02270	ENOG4105E0K	tonB-dependent siderophore receptor
G6Z48_RS02280	ENOG4106UW1	Major Facilitator superfamily
G6Z48_RS02285	ENOG4105E98	transcriptional regulator DeoR family
G6Z48_RS02295	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
G6Z48_RS02305	ENOG4105CR8	Transcriptional regulator
G6Z48_RS02310	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G6Z48_RS02315	ENOG4105T38	integral membrane protein
G6Z48_RS02320	ENOG4105JQN	Transcriptional regulator
G6Z48_RS02325	ENOG4105C57	major facilitator superfamily
G6Z48_RS02360	ENOG4105CC0	LysR family Transcriptional regulator
G6Z48_RS02365	ENOG4105II7	pyrroline-5-carboxylate reductase
G6Z48_RS02370	ENOG4105DFA	alanine racemase domain protein
G6Z48_RS02375	ENOG4105CZX	twitching motility protein
G6Z48_RS02380	ENOG4105CZX	twitching motility protein
G6Z48_RS02385	ENOG4107SET	aldo keto reductase
G6Z48_RS02390	ENOG4105EQ2	LysR family Transcriptional regulator
G6Z48_RS02405	ENOG4108R3E	Dna-3-methyladenine glycosylase i
G6Z48_RS02410	ENOG4108MAJ	Membrane
G6Z48_RS02415	ENOG4108UJU	UPF0301 protein
G6Z48_RS02420	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G6Z48_RS02425	ENOG4105CXT	aspartate transcarbamylase
G6Z48_RS02445	ENOG4105CJW	magnesium transporter
G6Z48_RS02450	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G6Z48_RS02465	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G6Z48_RS02470	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G6Z48_RS02475	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G6Z48_RS02480	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
G6Z48_RS02485	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6Z48_RS02490	ENOG4108IUZ	ABC transporter
G6Z48_RS02510	ENOG4105C2X	Arabinose 5-phosphate isomerase
G6Z48_RS02520	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G6Z48_RS02540	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G6Z48_RS02560	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G6Z48_RS02570	ENOG4105C02	permease
G6Z48_RS02580	ENOG4108S0S	Nucleotidyl transferase
G6Z48_RS02585	ENOG4105EHM	Aminoglycoside phosphotransferase
G6Z48_RS02590	ENOG4105Y3U	Transglycosylase-associated protein
G6Z48_RS02600	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
G6Z48_RS02625	ENOG4105CJ2	(LipO)protein
G6Z48_RS02645	ENOG4105D05	Receptor
G6Z48_RS02655	ENOG4107E2E	PKHD-type hydroxylase
G6Z48_RS02665	ENOG4108ESX	Receptor
G6Z48_RS02675	ENOG4105VQD	rieske 2fe-2S domain-containing protein
G6Z48_RS02690	ENOG4105C9B	Cysteine desulfurase
G6Z48_RS02695	ENOG4105JRK	feS assembly protein SufD
G6Z48_RS02700	ENOG4105C3K	feS assembly ATPase SufC
G6Z48_RS02725	ENOG4108Z0Z	intracellular protease Pfpi family
G6Z48_RS02750	ENOG4108Z9K	Osmotically inducible protein
G6Z48_RS02755	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G6Z48_RS02765	ENOG4105CFH	Aspartokinase
G6Z48_RS02775	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G6Z48_RS02790	ENOG4105EAH	synthase
G6Z48_RS02795	ENOG4105CG3	alpha amylase, catalytic region
G6Z48_RS02815	ENOG4107RBJ	symporter
G6Z48_RS02850	ENOG4105DA5	(ABC) transporter
G6Z48_RS02855	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS02860	ENOG4108UUM	single-stranded DNA-binding protein
G6Z48_RS02885	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G6Z48_RS02900	ENOG4105EAA	nucleoside
G6Z48_RS02910	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS02915	ENOG4105BZU	Histidine kinase
G6Z48_RS02925	ENOG4105BZU	Histidine kinase
G6Z48_RS02950	ENOG41082BM	Transcriptional regulator, arsr family
G6Z48_RS02965	ENOG4105VMP	Transcriptional regulator
G6Z48_RS02970	ENOG4105EE5	Membrane protein terC
G6Z48_RS02975	ENOG4105DIN	metallophosphoesterase
G6Z48_RS02980	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
G6Z48_RS02990	ENOG4105E18	UPF0276 protein
G6Z48_RS03000	ENOG4109045	doxx family
G6Z48_RS03020	ENOG4105E0F	Histidine kinase
G6Z48_RS03030	ENOG4105CSH	Transporter
G6Z48_RS03045	ENOG4105DRR	Transcriptional regulator, GntR family
G6Z48_RS03060	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
G6Z48_RS03065	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
G6Z48_RS03080	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
G6Z48_RS03090	ENOG4105CNM	Receptor
G6Z48_RS03095	ENOG4105DWT	malate dehydrogenase (quinone)
G6Z48_RS03120	ENOG4105DUX	Transporter
G6Z48_RS03135	ENOG4105EPD	Oligopeptide transporter, Opt family
G6Z48_RS03140	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
G6Z48_RS03155	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
G6Z48_RS03160	ENOG4107QMS	site-determining protein
G6Z48_RS03175	ENOG4105BZU	Histidine kinase
G6Z48_RS03180	ENOG4105WH1	Two component transcriptional regulator luxr family
G6Z48_RS03220	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
G6Z48_RS03230	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G6Z48_RS03240	ENOG4105GFR	rna polymerase sigma factor
G6Z48_RS03250	ENOG4105C29	acyl-CoA thioesterase
G6Z48_RS03270	ENOG4108TGP	Thioesterase superfamily protein
G6Z48_RS03275	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G6Z48_RS03280	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G6Z48_RS03285	ENOG4105K46	50S ribosomal protein l27
G6Z48_RS03290	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6Z48_RS03295	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
G6Z48_RS03300	ENOG4105CJR	Integral membrane protein (MviN
G6Z48_RS03305	ENOG4105DTN	riboflavin biosynthesis protein ribF
G6Z48_RS03310	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G6Z48_RS03315	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G6Z48_RS03320	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G6Z48_RS03345	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS03365	ENOG4105C5I	Dehydrogenase
G6Z48_RS03400	ENOG4105E2S	oxidase) subunit II
G6Z48_RS03405	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G6Z48_RS03410	ENOG4105CCU	oxidase (Subunit III)
G6Z48_RS03415	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
G6Z48_RS03420	ENOG4105BZU	Histidine kinase
G6Z48_RS03425	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G6Z48_RS03430	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
G6Z48_RS03450	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6Z48_RS03455	ENOG4107QWG	2-Nitropropane dioxygenase
G6Z48_RS03465	ENOG4105K5M	30s ribosomal protein S16
G6Z48_RS03470	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G6Z48_RS03475	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G6Z48_RS03480	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G6Z48_RS03500	ENOG4107QJQ	Mate efflux family protein
G6Z48_RS03510	ENOG4105VEJ	Heat shock protein
G6Z48_RS03520	ENOG4105CH6	catalase
G6Z48_RS03570	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G6Z48_RS03575	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G6Z48_RS03675	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
G6Z48_RS03760	ENOG4105D5K	Hemolysin activator protein
G6Z48_RS03835	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS03855	ENOG4107KET	secretion protein, HlyD family
G6Z48_RS03875	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G6Z48_RS03900	ENOG4108JPW	Aminotransferase
G6Z48_RS03905	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
G6Z48_RS03935	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G6Z48_RS03960	ENOG4105BZU	Histidine kinase
G6Z48_RS03965	ENOG4107RNH	Outer membrane receptor FepA
G6Z48_RS03980	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
G6Z48_RS03985	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G6Z48_RS03990	ENOG4105C9K	Endothelin-converting enzyme 1
G6Z48_RS03995	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS04000	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G6Z48_RS04005	ENOG4108JA2	transcriptioN-repair coupling factor
G6Z48_RS04015	ENOG4105D6S	protein involved in catabolism of external DNA
G6Z48_RS04020	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G6Z48_RS04025	ENOG4105EB3	Histidine kinase
G6Z48_RS04030	ENOG4105CT7	inner membrane cred family protein
G6Z48_RS04045	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G6Z48_RS04050	ENOG4105MYN	Zinc uptake regulation protein
G6Z48_RS04070	ENOG4105UGU	tonB-dependent Receptor
G6Z48_RS04090	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G6Z48_RS04130	ENOG4105BZU	Histidine kinase
G6Z48_RS04135	ENOG4105BZU	Histidine kinase
G6Z48_RS04140	ENOG4105FE9	pseudouridine synthase
G6Z48_RS04145	ENOG4105BZU	Histidine kinase
G6Z48_RS04150	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G6Z48_RS04175	ENOG4105BZ1	(ABC) transporter
G6Z48_RS04180	ENOG4105D6F	Phosphatase
G6Z48_RS04185	ENOG4105FN4	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity)
G6Z48_RS04245	ENOG4108YXA	Membrane
G6Z48_RS04250	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G6Z48_RS04265	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G6Z48_RS04270	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6Z48_RS04275	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6Z48_RS04285	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6Z48_RS04290	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6Z48_RS04295	ENOG4105DZP	Membrane-associated zinc metalloprotease
G6Z48_RS04305	ENOG4105KNE	Phosphatidate cytidylyltransferase
G6Z48_RS04310	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G6Z48_RS04315	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G6Z48_RS04320	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G6Z48_RS04325	ENOG4105BZU	Histidine kinase
G6Z48_RS04330	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G6Z48_RS04335	ENOG4105CE9	30S ribosomal protein S2
G6Z48_RS04355	ENOG4105CW0	outer membrane usher protein
G6Z48_RS04370	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G6Z48_RS04375	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G6Z48_RS04390	ENOG4105KUZ	arsenate reductase
G6Z48_RS04395	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G6Z48_RS04400	ENOG4105CAQ	asparagine synthetase
G6Z48_RS04415	ENOG4108UWD	Iron-storage protein
G6Z48_RS04420	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6Z48_RS04440	ENOG4105CW7	secretion protein, HlyD family
G6Z48_RS04445	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G6Z48_RS04460	ENOG4105EGI	Transcriptional regulator
G6Z48_RS04480	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G6Z48_RS04490	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G6Z48_RS04495	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS04500	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G6Z48_RS04505	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G6Z48_RS04515	ENOG4105E0F	Histidine kinase
G6Z48_RS04520	ENOG4105BZU	Histidine kinase
G6Z48_RS04525	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
G6Z48_RS04530	ENOG4109045	doxx family
G6Z48_RS04540	ENOG4105E18	UPF0276 protein
G6Z48_RS04550	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G6Z48_RS04555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G6Z48_RS04560	ENOG4105E2Z	phosphate ABC transporter (Permease
G6Z48_RS04565	ENOG4105C8U	phosphate abc transporter
G6Z48_RS04570	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G6Z48_RS04575	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G6Z48_RS04585	ENOG4105CSM	endonuclease III
G6Z48_RS04595	ENOG4105E39	Enoyl-CoA hydratase
G6Z48_RS04600	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G6Z48_RS04605	ENOG4105P8F	nudix hydrolase
G6Z48_RS04610	ENOG4105KHC	sulfurtransferase
G6Z48_RS04625	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G6Z48_RS04645	ENOG4106BRA	Membrane
G6Z48_RS04655	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G6Z48_RS04660	ENOG4105C26	Dehydrogenase
G6Z48_RS04670	ENOG4105CSH	Transporter
G6Z48_RS04675	ENOG4105W3S	hemerythrin-like, metal-binding protein
G6Z48_RS04695	ENOG4105CJP	fad dependent oxidoreductase
G6Z48_RS04700	ENOG4108Z86	Glutamine amidotransferase
G6Z48_RS04705	ENOG4105CFQ	glutamine synthetase
G6Z48_RS04715	ENOG4105H3G	oxidoreductase
G6Z48_RS04720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6Z48_RS04725	ENOG4105F38	ABC transporter, permease
G6Z48_RS04730	ENOG4105D38	putrescine abc transporter
G6Z48_RS04735	ENOG4105C26	Dehydrogenase
G6Z48_RS04750	ENOG4108JU5	Magnesium and cobalt efflux protein
G6Z48_RS04770	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G6Z48_RS04775	ENOG4105C9A	Phoh family
G6Z48_RS04780	ENOG4105D0S	secretion protein (HlyD
G6Z48_RS04785	ENOG4105CJ1	ABC, transporter
G6Z48_RS04790	ENOG4107QWP	ABC-2 type transporter
G6Z48_RS04795	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G6Z48_RS04800	ENOG4108RXX	maleylacetoacetate isomerase
G6Z48_RS04810	ENOG4105E4C	Lytic transglycosylase catalytic
G6Z48_RS04815	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G6Z48_RS04820	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G6Z48_RS04825	ENOG4105EIX	cytochrome c1
G6Z48_RS04830	ENOG4107MKT	Stringent starvation protein a
G6Z48_RS04835	ENOG4105KB2	stringent starvation protein b
G6Z48_RS04850	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G6Z48_RS04860	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G6Z48_RS04865	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G6Z48_RS04875	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6Z48_RS04880	ENOG4105M2J	Glutaredoxin
G6Z48_RS04890	ENOG4108KPZ	tonB-dependent Receptor
G6Z48_RS04895	ENOG4105EWT	decarboxylase family
G6Z48_RS04940	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G6Z48_RS04980	ENOG4105GNX	MltA-interacting MipA family protein
G6Z48_RS04985	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G6Z48_RS04990	ENOG4106F60	Histidine kinase
G6Z48_RS05010	ENOG4105BZ1	(ABC) transporter
G6Z48_RS05015	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G6Z48_RS05020	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G6Z48_RS05035	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G6Z48_RS05050	ENOG4105DFP	Integrase
G6Z48_RS05065	ENOG4106NZI	LysR family Transcriptional regulator
G6Z48_RS05090	ENOG4108ZIT	Ferredoxin, 2FE-2S
G6Z48_RS05105	ENOG4105KTU	Transcriptional regulator, arsr family
G6Z48_RS05110	ENOG4107QN2	dihydrolipoyl dehydrogenase
G6Z48_RS05125	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS05150	ENOG4107Y80	Major Facilitator superfamily
G6Z48_RS05155	ENOG4105PGM	cation diffusion facilitator family transporter
G6Z48_RS05170	ENOG4105C59	p-type ATPase
G6Z48_RS05185	ENOG4105DXI	Major Facilitator superfamily
G6Z48_RS05200	ENOG4105C6F	GntR Family Transcriptional Regulator
G6Z48_RS05220	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G6Z48_RS05270	ENOG4105W5Q	DNA repair protein (RadC
G6Z48_RS05325	ENOG4105VT3	DNA binding domain protein, excisionase family
G6Z48_RS05335	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
G6Z48_RS05530	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G6Z48_RS05540	ENOG4105W1Y	Transcriptional regulator
G6Z48_RS05555	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G6Z48_RS05560	ENOG4107YH6	single-stranded DNA-binding protein
G6Z48_RS05635	ENOG4107R39	(ABC) transporter
G6Z48_RS05715	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
G6Z48_RS05745	ENOG4106NZI	LysR family Transcriptional regulator
G6Z48_RS05765	ENOG4105E7U	AraC family transcriptional regulator
G6Z48_RS05770	ENOG41082CG	Protein CrcB homolog
G6Z48_RS05790	ENOG4105C58	cytochrome c oxidase accessory protein ccog
G6Z48_RS05805	ENOG4105D4P	Coproporphyrinogen iii oxidase
G6Z48_RS05820	ENOG4107QQG	Dehydrogenase
G6Z48_RS05825	ENOG4105CBC	glutamate synthase
G6Z48_RS05830	ENOG4105K5X	acetyltransferase
G6Z48_RS05850	ENOG4105C72	UPF0176 protein
G6Z48_RS05855	ENOG4105DEN	Luciferase family
G6Z48_RS05890	ENOG4105D9U	N-acetyltransferase
G6Z48_RS05895	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6Z48_RS05905	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G6Z48_RS05910	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G6Z48_RS05925	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G6Z48_RS05930	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G6Z48_RS05935	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
G6Z48_RS05940	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G6Z48_RS05945	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
G6Z48_RS05950	ENOG4108DG9	Smr protein MutS2
G6Z48_RS05955	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G6Z48_RS05960	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G6Z48_RS05970	ENOG4108K5P	(LipO)protein
G6Z48_RS05985	ENOG4105HBR	Rna-binding protein
G6Z48_RS05990	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G6Z48_RS05995	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G6Z48_RS06005	ENOG4105EEI	dihydropteroate synthase
G6Z48_RS06010	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G6Z48_RS06015	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G6Z48_RS06020	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G6Z48_RS06025	ENOG4107TH8	cina domain protein
G6Z48_RS06030	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G6Z48_RS06035	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G6Z48_RS06040	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G6Z48_RS06045	ENOG4105Y3E	Modulates RecA activity (By similarity)
G6Z48_RS06050	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G6Z48_RS06055	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
G6Z48_RS06080	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G6Z48_RS06105	ENOG4105DGI	Alkaline phosphatase
G6Z48_RS06110	ENOG4105HSS	phospholipase C
G6Z48_RS06125	ENOG4105NQN	cytochrome C
G6Z48_RS06140	ENOG4106UW1	Major Facilitator superfamily
G6Z48_RS06150	ENOG4105CNM	Receptor
G6Z48_RS06160	ENOG4105EQ1	Transcriptional regulator
G6Z48_RS06185	ENOG4105DWF	phosphomethylpyrimidine kinase
G6Z48_RS06200	ENOG4108IAB	Phoh family
G6Z48_RS06205	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6Z48_RS06215	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G6Z48_RS06225	ENOG4108Z4U	Ferredoxin
G6Z48_RS06240	ENOG4105DJ0	Poly(A) Polymerase
G6Z48_RS06245	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6Z48_RS06250	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G6Z48_RS06255	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G6Z48_RS06265	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G6Z48_RS06270	ENOG4107QP8	phosphohexose isomerase
G6Z48_RS06280	ENOG4105TX3	Histidine kinase
G6Z48_RS06285	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G6Z48_RS06290	ENOG410841Q	phosphoesterase PA-phosphatase related protein
G6Z48_RS06300	ENOG4108UHU	Aldolase
G6Z48_RS06305	ENOG4105C01	Dihydroxy-acid dehydratase
G6Z48_RS06315	ENOG4105CHC	glucokinase (EC 2.7.1.2)
G6Z48_RS06320	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
G6Z48_RS06340	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
G6Z48_RS06350	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G6Z48_RS06355	ENOG4105E33	succinate dehydrogenase
G6Z48_RS06360	ENOG410681N	tpr repeat protein
G6Z48_RS06370	ENOG4105D60	lipoprotein releasing system transmembrane protein
G6Z48_RS06385	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
G6Z48_RS06390	ENOG4105CEN	a g-specific adenine glycosylase
G6Z48_RS06395	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G6Z48_RS06420	ENOG4106H78	methyltransferase
G6Z48_RS06425	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G6Z48_RS06435	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G6Z48_RS06440	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G6Z48_RS06445	ENOG4105C8F	Beta-lactamase domain protein
G6Z48_RS06465	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G6Z48_RS06485	ENOG4105F0N	pyrophosphate phospho-hydrolase
G6Z48_RS06495	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G6Z48_RS06500	ENOG4108ZG0	Ompa motb domain protein
G6Z48_RS06505	ENOG4105CR8	Transcriptional regulator
G6Z48_RS06605	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G6Z48_RS06610	ENOG4108Z1B	Cyclase dehydrase
G6Z48_RS06620	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G6Z48_RS06625	ENOG41090R7	Ferric uptake
G6Z48_RS06635	ENOG4105HEI	LysR family (Transcriptional regulator
G6Z48_RS06640	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G6Z48_RS06645	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G6Z48_RS06650	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6Z48_RS06655	ENOG4105CFG	Acts as a chaperone (By similarity)
G6Z48_RS06660	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G6Z48_RS06665	ENOG4105R1U	AraC Family Transcriptional Regulator
G6Z48_RS06670	ENOG4105EU0	Major facilitator Superfamily
G6Z48_RS06690	ENOG4105BZ1	(ABC) transporter
G6Z48_RS06710	ENOG4105BZU	Histidine kinase
G6Z48_RS06715	ENOG4108URH	decarboxylase
G6Z48_RS06720	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G6Z48_RS06725	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G6Z48_RS06735	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G6Z48_RS06740	ENOG4105VIE	preprotein translocase, subunit YajC
G6Z48_RS06745	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G6Z48_RS06750	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G6Z48_RS06755	ENOG4105RKW	reductase (By
G6Z48_RS06765	ENOG4105CBX	hi0933 family
G6Z48_RS06770	ENOG4108VWS	Yaeq family
G6Z48_RS06775	ENOG4105D3G	Pseudouridine synthase
G6Z48_RS06780	ENOG4108UPT	UPF0178 protein
G6Z48_RS06785	ENOG4105VEQ	Cold shock protein
G6Z48_RS06795	ENOG4105CNG	UPF0061 protein
G6Z48_RS06805	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G6Z48_RS06810	ENOG4105C1J	atp-dependent rna helicase
G6Z48_RS06815	ENOG4105HMI	Membrane
G6Z48_RS06820	ENOG4105DUM	transcriptional regulator, lysR family
G6Z48_RS06825	ENOG4105C5H	ABC transporter
G6Z48_RS06850	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS06870	ENOG4105DWY	Agmatine deiminase
G6Z48_RS06880	ENOG4105YK5	50S ribosomal protein L36
G6Z48_RS06885	ENOG4105CAT	Cytidine monophosphate kinase
G6Z48_RS06890	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G6Z48_RS06895	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G6Z48_RS06905	ENOG4105CFV	Tetratricopeptide repeat protein
G6Z48_RS06910	ENOG4105ESV	Glycosyl transferase, family 4
G6Z48_RS06920	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G6Z48_RS06925	ENOG4105CHU	acetyl-coa acetyltransferase
G6Z48_RS06940	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G6Z48_RS06945	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G6Z48_RS06950	ENOG4105RQ9	TPR repeat-containing protein
G6Z48_RS06955	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
G6Z48_RS06955	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
G6Z48_RS06965	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G6Z48_RS06970	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G6Z48_RS06990	ENOG4105D06	uba thif-type nad fad binding protein
G6Z48_RS06995	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G6Z48_RS07005	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G6Z48_RS07010	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6Z48_RS07015	ENOG4105DFP	Integrase
G6Z48_RS07035	ENOG4108YGG	dna repair protein
G6Z48_RS07055	ENOG4105FA0	parb-like partition protein
G6Z48_RS07100	ENOG4107QJE	Chromosome Partitioning Protein
G6Z48_RS07125	ENOG4105C0D	helicase
G6Z48_RS07140	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G6Z48_RS07165	ENOG4106NZI	LysR family Transcriptional regulator
G6Z48_RS07275	ENOG4105D65	subunit l
G6Z48_RS07280	ENOG4105GND	monovalent cation H antiporter subunit B
G6Z48_RS07285	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G6Z48_RS07290	ENOG4108JPZ	Monovalent cation H antiporter subunit D
G6Z48_RS07305	ENOG4105KJM	monovalent cation h antiporter subunit g
G6Z48_RS07325	ENOG4105E0X	reductase
G6Z48_RS07340	ENOG4105CHU	acetyl-coa acetyltransferase
G6Z48_RS07345	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6Z48_RS07360	ENOG4105D7N	magnesium and cobalt transport protein CorA
G6Z48_RS07365	ENOG4105CYM	Glutathione S-transferase
G6Z48_RS07370	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6Z48_RS07390	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G6Z48_RS07435	ENOG4105CVR	type I restriction-modification system
G6Z48_RS07450	ENOG4105DZR	Type I site-specific deoxyribonuclease
G6Z48_RS07460	ENOG4105CC0	LysR family Transcriptional regulator
G6Z48_RS07500	ENOG4105DTD	Dehydrogenase
G6Z48_RS07510	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
G6Z48_RS07525	ENOG41082BM	Transcriptional regulator, arsr family
G6Z48_RS07540	ENOG4105CCI	Myosin-Cross-Reactive Antigen
G6Z48_RS07570	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS07575	ENOG4108UZX	fmn reductase
G6Z48_RS07585	ENOG4105DEN	Luciferase family
G6Z48_RS07595	ENOG4105CH2	amidohydrolase
G6Z48_RS07600	ENOG4108MJ3	acetyltransferase
G6Z48_RS07605	ENOG4105CDA	abc transporter atp-binding protein
G6Z48_RS07610	ENOG4105EAB	amino acid AbC transporter
G6Z48_RS07635	ENOG4108IG5	Transcriptional regulator
G6Z48_RS07640	ENOG41066DG	(EAL) domain protein
G6Z48_RS07645	ENOG4105HEI	LysR family (Transcriptional regulator
G6Z48_RS07650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G6Z48_RS07655	ENOG4105UBK	short-chain dehydrogenase reductase
G6Z48_RS07665	ENOG4105WZW	rhodanese family
G6Z48_RS07685	ENOG4108RZE	Tetr family transcriptional regulator
G6Z48_RS07700	ENOG4105DFI	Membrane
G6Z48_RS07705	ENOG4105D4A	Cell wall formation (By similarity)
G6Z48_RS07710	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G6Z48_RS07725	ENOG4107ZQV	short-chain dehydrogenase reductase
G6Z48_RS07730	ENOG4105C26	Dehydrogenase
G6Z48_RS07770	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6Z48_RS07780	ENOG4105BZU	Histidine kinase
G6Z48_RS07785	ENOG4105BZU	Histidine kinase
G6Z48_RS07790	ENOG4107Z5C	methylesterase
G6Z48_RS07795	ENOG4108KXV	response regulator
G6Z48_RS07800	ENOG41080HT	Transcriptional regulator, arsr family
G6Z48_RS07840	ENOG4105CFH	Aspartokinase
G6Z48_RS07845	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
G6Z48_RS07855	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G6Z48_RS07860	ENOG4105CUT	histidyl-tRNA synthetase
G6Z48_RS07870	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G6Z48_RS07875	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G6Z48_RS07880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G6Z48_RS07885	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G6Z48_RS07890	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G6Z48_RS07895	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G6Z48_RS07900	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G6Z48_RS07905	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G6Z48_RS07930	ENOG4106N3A	copper homeostasis protein cutc
G6Z48_RS07935	ENOG4107RNH	Outer membrane receptor FepA
G6Z48_RS07965	ENOG4105CWX	Alpha-1,2-mannosidase
G6Z48_RS07970	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS07980	ENOG4105D7K	pfkb domain protein
G6Z48_RS07995	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
G6Z48_RS08000	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
G6Z48_RS08005	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
G6Z48_RS08020	ENOG4105CUB	amino acid
G6Z48_RS08025	ENOG4105CUB	amino acid
G6Z48_RS08035	ENOG4108JQ1	Dehydrogenase
G6Z48_RS08040	ENOG4105CQB	FAD linked oxidase domain protein
G6Z48_RS08055	ENOG4105EB3	Histidine kinase
G6Z48_RS08060	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G6Z48_RS08065	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS08070	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS08085	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G6Z48_RS08095	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G6Z48_RS08115	ENOG4105CE1	Ferrous iron transport protein b
G6Z48_RS08130	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
G6Z48_RS08145	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G6Z48_RS08150	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G6Z48_RS08155	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G6Z48_RS08160	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G6Z48_RS08175	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G6Z48_RS08180	ENOG4105EDV	vault protein
G6Z48_RS08190	ENOG4105DY9	regulatoR
G6Z48_RS08205	ENOG4105C26	Dehydrogenase
G6Z48_RS08210	ENOG4105C7K	acetolactate synthase
G6Z48_RS08220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G6Z48_RS08225	ENOG4105BZU	Histidine kinase
G6Z48_RS08230	ENOG4105E39	Enoyl-CoA hydratase
G6Z48_RS08235	ENOG4105CEY	Amp-dependent synthetase and ligase
G6Z48_RS08240	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
G6Z48_RS08245	ENOG4105C26	Dehydrogenase
G6Z48_RS08250	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G6Z48_RS08255	ENOG4105C94	Transporter
G6Z48_RS08260	ENOG4107QM5	aconitate hydratase
G6Z48_RS08280	ENOG4107QIJ	Aconitate hydratase 2
G6Z48_RS08295	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G6Z48_RS08300	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G6Z48_RS08305	ENOG4105BZU	Histidine kinase
G6Z48_RS08310	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS08315	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS08325	ENOG4108V3W	Chemotaxis protein, CheW
G6Z48_RS08330	ENOG4108REP	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
G6Z48_RS08335	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS08340	ENOG4105CBS	Chea signal transduction histidine kinase
G6Z48_RS08345	ENOG4108VYJ	response regulator receiver protein
G6Z48_RS08355	ENOG4108V3W	Chemotaxis protein, CheW
G6Z48_RS08365	ENOG4105ER2	Ompa motb domain protein
G6Z48_RS08370	ENOG4105E14	MotA TolQ exbB proton channel
G6Z48_RS08380	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G6Z48_RS08385	ENOG4108VYJ	response regulator receiver protein
G6Z48_RS08390	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6Z48_RS08400	ENOG4105FZW	flagellar biosynthesis regulator FlhF
G6Z48_RS08405	ENOG4105D7B	Flagellar biosynthesis protein flha
G6Z48_RS08410	ENOG4105D00	flagellar biosynthetic protein flhB
G6Z48_RS08420	ENOG4105BZU	Histidine kinase
G6Z48_RS08425	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G6Z48_RS08430	ENOG4105VS8	Flagellar biosynthetic protein fliq
G6Z48_RS08435	ENOG4105CN7	Flagellar biosynthetic protein FliP
G6Z48_RS08440	ENOG4105K0P	flagellar biosynthesis protein
G6Z48_RS08445	ENOG4105DD5	Flagellar motor switch protein
G6Z48_RS08450	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G6Z48_RS08470	ENOG4108JIR	Flagellum-specific ATP synthase
G6Z48_RS08480	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G6Z48_RS08485	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G6Z48_RS08490	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
G6Z48_RS08515	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6Z48_RS08520	ENOG4105WH1	Two component transcriptional regulator luxr family
G6Z48_RS08535	ENOG4105MQ3	flagellar protein FliS
G6Z48_RS08540	ENOG4105DTS	flagellar hook-associated
G6Z48_RS08550	ENOG4105I03	Flagellin
G6Z48_RS08565	ENOG4105E1Q	flagellar hook-associated protein
G6Z48_RS08570	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G6Z48_RS08580	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G6Z48_RS08585	ENOG4105CGA	flagellar basal-body rod protein FlgG
G6Z48_RS08590	ENOG4108KPB	Flagellar basal-body rod protein FlgF
G6Z48_RS08595	ENOG4105BZE	flagellar hook protein, FlgE
G6Z48_RS08605	ENOG4108ZC9	flagellar basal-body rod protein flgc
G6Z48_RS08610	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G6Z48_RS08635	ENOG4105BZU	Histidine kinase
G6Z48_RS08640	ENOG4105BZU	Histidine kinase
G6Z48_RS08650	ENOG4105BZU	Histidine kinase
G6Z48_RS08670	ENOG41075W9	High frequency lysogenization protein HflD homolog
G6Z48_RS08675	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G6Z48_RS08690	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G6Z48_RS08700	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G6Z48_RS08730	ENOG4105C3M	thioredoxin reductase
G6Z48_RS08735	ENOG4105CNU	cell division protein FtsK
G6Z48_RS08750	ENOG4105D1H	recombination factor protein RarA
G6Z48_RS08765	ENOG4105NIV	Esterase
G6Z48_RS08775	ENOG4107R4I	Periplasmic binding protein
G6Z48_RS08780	ENOG4105EHG	Permease protein
G6Z48_RS08785	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G6Z48_RS08795	ENOG4108NVJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G6Z48_RS08810	ENOG4105BZU	Histidine kinase
G6Z48_RS08840	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G6Z48_RS08865	ENOG4105EMN	RNA polymerase sigma factor
G6Z48_RS08890	ENOG4105BZU	Histidine kinase
G6Z48_RS08900	ENOG4105KAV	tspo and mbr like protein
G6Z48_RS09100	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
G6Z48_RS09105	ENOG4105C7W	Xanthine dehydrogenase
G6Z48_RS09110	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
G6Z48_RS09115	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
G6Z48_RS09125	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G6Z48_RS09135	ENOG4105EQ2	LysR family Transcriptional regulator
G6Z48_RS09155	ENOG4108KPJ	rna polymerase sigma factor
G6Z48_RS09160	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G6Z48_RS09175	ENOG4107FW0	short-chain dehydrogenase reductase
G6Z48_RS09210	ENOG4105DQE	DNA ligase
G6Z48_RS09220	ENOG4108Z9Z	response to DNA damage stimulus
G6Z48_RS09245	ENOG4105WEF	catalase
G6Z48_RS09250	ENOG4108N8X	transition metal ion binding
G6Z48_RS09295	ENOG4105E2A	Dehydrogenase
G6Z48_RS09325	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS09330	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G6Z48_RS09335	ENOG4105DE4	1-phosphofructokinase
G6Z48_RS09340	ENOG4105DM4	PTS System
G6Z48_RS09355	ENOG4105KVH	Transcriptional regulator
G6Z48_RS09380	ENOG4105EDR	glucose galactose transporter
G6Z48_RS09385	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS09390	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
G6Z48_RS09405	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G6Z48_RS09420	ENOG4105C7F	AcnD-accessory protein PrpF
G6Z48_RS09425	ENOG4105F04	LysR family Transcriptional regulator
G6Z48_RS09455	ENOG4105DAE	Methylenetetrahydrofolate reductase
G6Z48_RS09460	ENOG4105DZ2	Transcriptional regulator
G6Z48_RS09465	ENOG4108UZX	fmn reductase
G6Z48_RS09490	ENOG4107R6D	beta-lactam binding protein AmpH
G6Z48_RS09515	ENOG41065SU	Two-component system sensor kinase
G6Z48_RS09525	ENOG4105CEY	Amp-dependent synthetase and ligase
G6Z48_RS09540	ENOG4107YCY	Transcriptional regulator
G6Z48_RS09555	ENOG4105EY3	heparinase II III family protein
G6Z48_RS09560	ENOG4105DPW	Major facilitator superfamily MFS_1
G6Z48_RS09575	ENOG4105D7K	pfkb domain protein
G6Z48_RS09600	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
G6Z48_RS09645	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6Z48_RS09720	ENOG4105BZU	Histidine kinase
G6Z48_RS09725	ENOG4105CGK	Exodeoxyribonuclease III
G6Z48_RS09730	ENOG4105CG3	alpha amylase, catalytic region
G6Z48_RS09735	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
G6Z48_RS09745	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
G6Z48_RS09760	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G6Z48_RS09770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6Z48_RS09775	ENOG4105EB3	Histidine kinase
G6Z48_RS09785	ENOG4105T0Z	Conserved Protein
G6Z48_RS09815	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
G6Z48_RS09825	ENOG4105BZU	Histidine kinase
G6Z48_RS09830	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G6Z48_RS09890	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
G6Z48_RS09915	ENOG4105C57	major facilitator superfamily
G6Z48_RS09955	ENOG4105HEI	LysR family (Transcriptional regulator
G6Z48_RS09960	ENOG4105CV8	reductase
G6Z48_RS09980	ENOG4105EQ2	LysR family Transcriptional regulator
G6Z48_RS09985	ENOG4105CHR	reductase
G6Z48_RS10005	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G6Z48_RS10010	ENOG4105DHQ	Histidine kinase
G6Z48_RS10015	ENOG4105CWX	Alpha-1,2-mannosidase
G6Z48_RS10030	ENOG4105CSH	Transporter
G6Z48_RS10050	ENOG4105BZU	Histidine kinase
G6Z48_RS10070	ENOG4105CNM	Receptor
G6Z48_RS10085	ENOG4105JQN	Transcriptional regulator
G6Z48_RS10090	ENOG4105EUB	pirin domain protein
G6Z48_RS10095	ENOG4105CHJ	isochorismatase hydrolase
G6Z48_RS10100	ENOG4105CHJ	isochorismatase hydrolase
G6Z48_RS10125	ENOG4105SG9	biopolymer transport protein, ExbD
G6Z48_RS10130	ENOG4105E02	MotA TolQ exbB proton channel
G6Z48_RS10150	ENOG4105VWV	general secretion pathway protein h
G6Z48_RS10155	ENOG4105X5Z	General secretion pathway protein I
G6Z48_RS10160	ENOG4108WWZ	General secretion pathway protein J
G6Z48_RS10170	ENOG4108UPW	ABC transporter
G6Z48_RS10175	ENOG4105D7Q	type ii secretion system
G6Z48_RS10180	ENOG4107QHF	type ii secretion system protein e
G6Z48_RS10185	ENOG4105GVR	general secretion pathway protein D
G6Z48_RS10205	ENOG4108VAU	general secretion pathway protein G
G6Z48_RS10225	ENOG410904A	RNA polymerase
G6Z48_RS10235	ENOG4105EW9	transcriptional regulator AsnC family
G6Z48_RS10270	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
G6Z48_RS10275	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
G6Z48_RS10280	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
G6Z48_RS10285	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G6Z48_RS10300	ENOG4105E0C	molybdate abc transporter
G6Z48_RS10305	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G6Z48_RS10315	ENOG4105D4P	Coproporphyrinogen iii oxidase
G6Z48_RS10325	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G6Z48_RS10330	ENOG41076YT	nitrate reductase, gamma subunit
G6Z48_RS10335	ENOG4105R3A	Nitrate reductase
G6Z48_RS10340	ENOG4108IUE	nitrate reductase beta subunit
G6Z48_RS10345	ENOG4105CRU	nitrate reductase, alpha subunit
G6Z48_RS10350	ENOG4105DQQ	Major facilitator superfamily MFS_1
G6Z48_RS10360	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G6Z48_RS10365	ENOG4108ZAF	Molybdopterin
G6Z48_RS10375	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G6Z48_RS10380	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G6Z48_RS10385	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G6Z48_RS10435	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G6Z48_RS10440	ENOG4105R1U	AraC Family Transcriptional Regulator
G6Z48_RS10455	ENOG4105Y49	secretion protein, HlyD family
G6Z48_RS10460	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS10480	ENOG4106F60	Histidine kinase
G6Z48_RS10485	ENOG41080IJ	Diacylglycerol kinase
G6Z48_RS10490	ENOG4105DIJ	Phosphoethanolamine transferase
G6Z48_RS10525	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
G6Z48_RS10530	ENOG4105C0W	non-ribosomal peptide synthetase
G6Z48_RS10535	ENOG4105WQI	isochorismatase
G6Z48_RS10540	ENOG4105WQI	isochorismatase
G6Z48_RS10545	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
G6Z48_RS10550	ENOG4105E4F	Isochorismate synthase
G6Z48_RS10560	ENOG4105EYF	MMPL domain protein
G6Z48_RS10565	ENOG4105DYW	oxidoreductase
G6Z48_RS10580	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6Z48_RS10590	ENOG4105WAP	TPR repeat-containing protein
G6Z48_RS10605	ENOG4105EJ2	Transcriptional regulator
G6Z48_RS10620	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS10630	ENOG4105KST	dependent repressor
G6Z48_RS10635	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
G6Z48_RS10650	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G6Z48_RS10655	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G6Z48_RS10665	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS10670	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS10675	ENOG4105C94	Transporter
G6Z48_RS10700	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
G6Z48_RS10705	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
G6Z48_RS10720	ENOG4105GAV	receptor
G6Z48_RS10740	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G6Z48_RS10750	ENOG4105UYK	outer membrane protein a
G6Z48_RS10755	ENOG4105EUR	Domain-Containing protein
G6Z48_RS10755	ENOG4105EUR	Domain-Containing protein
G6Z48_RS10840	ENOG4107SFI	Major Facilitator superfamily
G6Z48_RS10850	ENOG4105CI2	imidazolone-5-propionate hydrolase
G6Z48_RS10860	ENOG4105CHJ	isochorismatase hydrolase
G6Z48_RS10865	ENOG4107XVH	Transcriptional regulator
G6Z48_RS10875	ENOG4105BZU	Histidine kinase
G6Z48_RS10880	ENOG4105WH1	Two component transcriptional regulator luxr family
G6Z48_RS10885	ENOG4105EQ0	Major Facilitator superfamily
G6Z48_RS10890	ENOG4105EXG	Transcriptional regulator
G6Z48_RS10895	ENOG4105CPN	adenine deaminase
G6Z48_RS10905	ENOG4107NQ8	LysR family Transcriptional regulator
G6Z48_RS10930	ENOG4107RNH	Outer membrane receptor FepA
G6Z48_RS10960	ENOG4105CXG	d-lactate dehydrogenase
G6Z48_RS10965	ENOG4105DMF	Dehydrogenase
G6Z48_RS10970	ENOG41073TP	transcriptional regulator
G6Z48_RS10975	ENOG4105DAA	L-lactate
G6Z48_RS10980	ENOG4108302	MgtC SapB transporter
G6Z48_RS11005	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G6Z48_RS11010	ENOG4105JQN	Transcriptional regulator
G6Z48_RS11015	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
G6Z48_RS11035	ENOG4105JQN	Transcriptional regulator
G6Z48_RS11060	ENOG4105C0B	DNA polymerase III (alpha subunit)
G6Z48_RS11070	ENOG4105CSW	GntR family transcriptional regulator
G6Z48_RS11075	ENOG4105DFA	alanine racemase domain protein
G6Z48_RS11080	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6Z48_RS11095	ENOG4108SF5	RNA Polymerase
G6Z48_RS11130	ENOG4105CXN	decarboxylase
G6Z48_RS11135	ENOG4105D5Q	Arginine ornithine antiporter
G6Z48_RS11145	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
G6Z48_RS11150	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6Z48_RS11160	ENOG4105W1Y	Transcriptional regulator
G6Z48_RS11335	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G6Z48_RS11385	ENOG4105NVB	glycoside hydrolase, family 19
G6Z48_RS11395	ENOG4106FAK	Endodeoxyribonuclease RusA
G6Z48_RS11565	ENOG4107SDU	Methyl-accepting chemotaxis
G6Z48_RS11585	ENOG4105BZU	Histidine kinase
G6Z48_RS11590	ENOG4105BZM	domain protein
G6Z48_RS11605	ENOG41067S9	phage shock protein C, PspC
G6Z48_RS11610	ENOG4105M0Y	
G6Z48_RS11615	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G6Z48_RS11630	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G6Z48_RS11635	ENOG4107QJQ	Mate efflux family protein
G6Z48_RS11655	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G6Z48_RS11680	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G6Z48_RS11685	ENOG4108Z6B	deaminase
G6Z48_RS11690	ENOG4105KVH	Transcriptional regulator
G6Z48_RS11695	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
G6Z48_RS11700	ENOG4105K5X	acetyltransferase
G6Z48_RS11775	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
G6Z48_RS11795	ENOG4105CMA	conjugation trbi family protein
G6Z48_RS11830	ENOG4105F27	Major Facilitator
G6Z48_RS11835	ENOG4108Z4X	TRANSCRIPTIONal
G6Z48_RS11870	ENOG4105CQZ	Histidine kinase
G6Z48_RS11885	ENOG4105E0K	tonB-dependent siderophore receptor
G6Z48_RS11905	ENOG4105KVH	Transcriptional regulator
G6Z48_RS11910	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
G6Z48_RS11920	ENOG41088T4	Helicase IV
G6Z48_RS11935	ENOG4105CC0	LysR family Transcriptional regulator
G6Z48_RS11940	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
G6Z48_RS11945	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G6Z48_RS11960	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G6Z48_RS11970	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G6Z48_RS12020	ENOG4105CI2	imidazolone-5-propionate hydrolase
G6Z48_RS12035	ENOG4105CGP	Urocanate hydratase
G6Z48_RS12085	ENOG4105DWY	Agmatine deiminase
G6Z48_RS12090	ENOG4105ETT	transcriptional Regulator, LysR family
G6Z48_RS12140	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS12145	ENOG4105DZG	Dehydrogenase
G6Z48_RS12150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6Z48_RS12155	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
G6Z48_RS12165	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
G6Z48_RS12175	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G6Z48_RS12180	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G6Z48_RS12185	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
G6Z48_RS12195	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G6Z48_RS12200	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G6Z48_RS12205	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G6Z48_RS12210	ENOG4106611	bacteriocin immunity
G6Z48_RS12215	ENOG4108Z4V	iron-sulfur cluster assembly
G6Z48_RS12220	ENOG4105C5S	asparaginyl-tRNA synthetase
G6Z48_RS12240	ENOG41077A9	carbonic anhydrase
G6Z48_RS12250	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
G6Z48_RS12255	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
G6Z48_RS12260	ENOG4105CJB	Exodeoxyribonuclease I
G6Z48_RS12280	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G6Z48_RS12285	ENOG4105C7I	Dehydrogenase
G6Z48_RS12295	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS12300	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS12315	ENOG4105C1G	acyl-Coa dehydrogenase
G6Z48_RS12320	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G6Z48_RS12325	ENOG4105C3R	Methionine synthase
G6Z48_RS12330	ENOG4105C3R	Methionine synthase
G6Z48_RS12350	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G6Z48_RS12355	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G6Z48_RS12360	ENOG4108V06	Glutathione peroxidase
G6Z48_RS12370	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
G6Z48_RS12375	ENOG4105CZV	ABC transporter
G6Z48_RS12400	ENOG4105C9Q	fumarate hydratase class II
G6Z48_RS12405	ENOG4107QTF	adenylosuccinate lyase
G6Z48_RS12415	ENOG4105EZE	Cupin 4 family protein
G6Z48_RS12425	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G6Z48_RS12430	ENOG4105C7S	Dehydrogenase
G6Z48_RS12450	ENOG4105DGI	Alkaline phosphatase
G6Z48_RS12460	ENOG4105CDU	Replicative dna helicase
G6Z48_RS12475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G6Z48_RS12500	ENOG4105F8V	Hydrolase, tatD family
G6Z48_RS12505	ENOG4105CUZ	uba thif-type nad fad binding protein
G6Z48_RS12520	ENOG4105VEQ	Cold shock protein
G6Z48_RS12530	ENOG4105HDD	phospholipase
G6Z48_RS12540	ENOG4108TGY	Glutathione S-transferase
G6Z48_RS12550	ENOG4107GFK	fumarate
G6Z48_RS12555	ENOG4108KPJ	rna polymerase sigma factor
G6Z48_RS12560	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
G6Z48_RS12570	ENOG4105DP0	ferredoxin-NADP reductase
G6Z48_RS12580	ENOG4105DGW	oligopeptidase A
G6Z48_RS12590	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G6Z48_RS12615	ENOG4105DUX	Transporter
G6Z48_RS12625	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6Z48_RS12645	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
G6Z48_RS12650	ENOG41090A4	Pterin carbinolamine dehydratase
G6Z48_RS12660	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
G6Z48_RS12665	ENOG4105EI2	Pseudouridine synthase
G6Z48_RS12670	ENOG4105C03	ribonuclease
G6Z48_RS12685	ENOG4105DRS	transport system, permease
G6Z48_RS12715	ENOG4105M85	Bola protein
G6Z48_RS12720	ENOG4105K9H	YciI-like protein
G6Z48_RS12725	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G6Z48_RS12730	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G6Z48_RS12735	ENOG4105FE9	pseudouridine synthase
G6Z48_RS12745	ENOG4105E5M	Multidrug resistance protein D
G6Z48_RS12765	ENOG4105CHM	Aminotransferase
G6Z48_RS12770	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
G6Z48_RS12775	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
G6Z48_RS12780	ENOG41060IM	Heme exporter protein
G6Z48_RS12790	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
G6Z48_RS12795	ENOG4105DA4	cytochrome c-type biogenesis protein
G6Z48_RS12805	ENOG4105KWW	Biogenesis protein
G6Z48_RS12810	ENOG4108M1T	Cytochrome c-type biogenesis protein
G6Z48_RS12815	ENOG4105DWV	Homoserine O-trans-acetylase
G6Z48_RS12825	ENOG4108JJ8	(ABC) transporter
G6Z48_RS12830	ENOG4108JJ9	ABC, transporter
G6Z48_RS12835	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G6Z48_RS12840	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G6Z48_RS12870	ENOG4107BJW	polysaccharide deacetylase
G6Z48_RS12875	ENOG4105CND	Glycosyl transferase, family 2
G6Z48_RS12885	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G6Z48_RS12900	ENOG4105CH7	arginosuccinase
G6Z48_RS12905	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G6Z48_RS12915	ENOG4105CAS	nag kinase
G6Z48_RS12925	ENOG4105CDH	Citrulline--aspartate ligase
G6Z48_RS12930	ENOG4105DBV	ornithine carbamoyltransferase
G6Z48_RS12940	ENOG4105C8N	cysteinyl-tRNA synthetase
G6Z48_RS12945	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
G6Z48_RS12960	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G6Z48_RS12965	ENOG4105CD3	dihydroorotase
G6Z48_RS12980	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G6Z48_RS12985	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G6Z48_RS12990	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G6Z48_RS12995	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G6Z48_RS13000	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G6Z48_RS13005	ENOG4105BZU	Histidine kinase
G6Z48_RS13025	ENOG4105D0M	Protease HtpX homolog
G6Z48_RS13030	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G6Z48_RS13035	ENOG4105CHR	reductase
G6Z48_RS13055	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G6Z48_RS13060	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G6Z48_RS13065	ENOG4105K8N	protein family UPF0079, ATPase
G6Z48_RS13070	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G6Z48_RS13075	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G6Z48_RS13080	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G6Z48_RS13095	ENOG4105E6M	Sulphatase-modifying factor protein
G6Z48_RS13115	ENOG4107ZSV	Receptor
G6Z48_RS13140	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G6Z48_RS13145	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
G6Z48_RS13170	ENOG4105CSU	acyl-Coa dehydrogenase
G6Z48_RS13180	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G6Z48_RS13215	ENOG410814C	multidrug resistance protein
G6Z48_RS13225	ENOG410829K	Lysine exporter protein (Lyse ygga)
G6Z48_RS13230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G6Z48_RS13280	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G6Z48_RS13285	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G6Z48_RS13290	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G6Z48_RS13295	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G6Z48_RS13300	ENOG41082NX	50s ribosomal protein l35
G6Z48_RS13305	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G6Z48_RS13310	ENOG4105C22	threonyL-tRNA synthetase
G6Z48_RS13330	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6Z48_RS13340	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G6Z48_RS13345	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G6Z48_RS13355	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G6Z48_RS13360	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G6Z48_RS13365	ENOG4105CHV	Transcription elongation factor NusA
G6Z48_RS13370	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G6Z48_RS13385	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6Z48_RS13390	ENOG4105C8S	subunit m
G6Z48_RS13395	ENOG4105D65	subunit l
G6Z48_RS13400	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6Z48_RS13405	ENOG4105DF2	NADH dehydrogenase subunit j
G6Z48_RS13410	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6Z48_RS13420	ENOG4107R0R	NADH dehydrogenase subunit g
G6Z48_RS13430	ENOG4105GKE	subunit e
G6Z48_RS13435	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6Z48_RS13440	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6Z48_RS13445	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6Z48_RS13450	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6Z48_RS13465	ENOG4105CP7	Triose-phosphate isomerase
G6Z48_RS13480	ENOG4105E68	Sulfatase
G6Z48_RS13485	ENOG4108PQP	glycosyl transferase group 1
G6Z48_RS13490	ENOG4107BJW	polysaccharide deacetylase
G6Z48_RS13495	ENOG4105CMR	udp-glucose 4-epimerase
G6Z48_RS13500	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G6Z48_RS13505	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G6Z48_RS13510	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G6Z48_RS13520	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G6Z48_RS13540	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G6Z48_RS13545	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G6Z48_RS13560	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G6Z48_RS13570	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G6Z48_RS13575	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G6Z48_RS13585	ENOG4105DJ4	phosphatidylserine decarboxylase
G6Z48_RS13600	ENOG4105D7A	ATP-binding protein
G6Z48_RS13605	ENOG4108RRZ	Transcription elongation factor GreB
G6Z48_RS13615	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G6Z48_RS13635	ENOG4105DHP	deoxycytidine triphosphate deaminase
G6Z48_RS13645	ENOG4105D05	Receptor
G6Z48_RS13650	ENOG4105D05	Receptor
G6Z48_RS13655	ENOG4105C9K	Endothelin-converting enzyme 1
G6Z48_RS13660	ENOG4108KPZ	tonB-dependent Receptor
G6Z48_RS13690	ENOG4107RT3	EamA-like transporter family
G6Z48_RS13700	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G6Z48_RS13710	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G6Z48_RS13715	ENOG4105K4H	Nlp p60 protein
G6Z48_RS13720	ENOG4105K4H	Nlp p60 protein
G6Z48_RS13740	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G6Z48_RS13745	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G6Z48_RS13750	ENOG4105CTB	Polyprenyl synthetase
G6Z48_RS13760	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G6Z48_RS13765	ENOG4105N42	UPF0307 protein
G6Z48_RS13770	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G6Z48_RS13780	ENOG4105C03	ribonuclease
G6Z48_RS13785	ENOG4108Z03	MAF-like protein
G6Z48_RS13790	ENOG4105MPN	Membrane
G6Z48_RS13800	ENOG4105D05	Receptor
G6Z48_RS13805	ENOG4105D5Q	Arginine ornithine antiporter
G6Z48_RS13815	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G6Z48_RS13825	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G6Z48_RS13840	ENOG4105C8T	Leucyl-tRNA synthetase
G6Z48_RS13850	ENOG4107QR8	Thioredoxin
G6Z48_RS13890	ENOG4105FQP	Beta-lactamase
G6Z48_RS13895	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
G6Z48_RS13905	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G6Z48_RS13915	ENOG4108R3D	Electron transport complex
G6Z48_RS13920	ENOG4105M4H	endoribonuclease L-psp
G6Z48_RS13955	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G6Z48_RS13960	ENOG4105CFG	Acts as a chaperone (By similarity)
G6Z48_RS14000	ENOG4105KSC	Transcriptional regulator, TraR DksA family
G6Z48_RS14005	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
G6Z48_RS14010	ENOG4108VKG	metal-dependent hydrolase
G6Z48_RS14020	ENOG4107RZC	phospholipase d
G6Z48_RS14040	ENOG4105CHU	acetyl-coa acetyltransferase
G6Z48_RS14055	ENOG4105CSU	acyl-Coa dehydrogenase
G6Z48_RS14065	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
G6Z48_RS14070	ENOG4107QRT	dEAD DEAH box helicase
G6Z48_RS14085	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
G6Z48_RS14090	ENOG4105VEQ	Cold shock protein
G6Z48_RS14095	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
G6Z48_RS14100	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G6Z48_RS14105	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
G6Z48_RS14110	ENOG4107ZXU	DSBA oxidoreductase
G6Z48_RS14120	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G6Z48_RS14125	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
G6Z48_RS14140	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G6Z48_RS14145	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G6Z48_RS14150	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G6Z48_RS14160	ENOG4105C3F	Signal peptidase i
G6Z48_RS14165	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G6Z48_RS14170	ENOG4105C0H	protease
G6Z48_RS14180	ENOG4105EMN	RNA polymerase sigma factor
G6Z48_RS14190	ENOG4105EUB	pirin domain protein
G6Z48_RS14195	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G6Z48_RS14205	ENOG4105EUB	pirin domain protein
G6Z48_RS14210	ENOG4105D22	carbon starvation protein
G6Z48_RS14215	ENOG4105VCD	cytoplasmic protein
G6Z48_RS14230	ENOG4105EB3	Histidine kinase
G6Z48_RS14250	ENOG4105DIJ	Phosphoethanolamine transferase
G6Z48_RS14270	ENOG4105C2C	drug resistance transporter, Bcr CflA
G6Z48_RS14275	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6Z48_RS14285	ENOG4105C85	amino acid
G6Z48_RS14290	ENOG4106AXJ	AraC family transcriptional regulator
G6Z48_RS14320	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS14325	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
G6Z48_RS14330	ENOG4105DR5	peptidase
G6Z48_RS14340	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G6Z48_RS14350	ENOG4105EPW	hflc protein
G6Z48_RS14355	ENOG4107QJR	hflk protein
G6Z48_RS14365	ENOG4105M3Z	response regulator
G6Z48_RS14385	ENOG4108JQB	penicillin-binding protein 1C
G6Z48_RS14390	ENOG4105DN3	alpha-2-macroglobulin domain protein
G6Z48_RS14395	ENOG4105DXD	2-methylcitrate dehydratase
G6Z48_RS14400	ENOG4105C7F	AcnD-accessory protein PrpF
G6Z48_RS14405	ENOG4108I0Z	Aconitate hydratase
G6Z48_RS14410	ENOG4105BZN	citrate synthase
G6Z48_RS14415	ENOG4105CR4	methylisocitrate lyase
G6Z48_RS14420	ENOG4108JU7	Transcriptional regulator
G6Z48_RS14435	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
G6Z48_RS14440	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G6Z48_RS14455	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G6Z48_RS14460	ENOG4105D49	3-dehydroquinate synthase
G6Z48_RS14475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G6Z48_RS14480	ENOG4105BZU	Histidine kinase
G6Z48_RS14485	ENOG4105BZU	Histidine kinase
G6Z48_RS14495	ENOG4105DS1	cytochrome b561
G6Z48_RS14510	ENOG4105EJQ	L-serine dehydratase
G6Z48_RS14515	ENOG4105D74	hydrolase
G6Z48_RS14520	ENOG4105CFH	Aspartokinase
G6Z48_RS14525	ENOG4105C28	cystathionine
G6Z48_RS14530	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
G6Z48_RS14535	ENOG4105DR5	peptidase
G6Z48_RS14540	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G6Z48_RS14545	ENOG4108UT2	hemolysin iii
G6Z48_RS14570	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G6Z48_RS14575	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G6Z48_RS14590	ENOG4108IG5	Transcriptional regulator
G6Z48_RS14600	ENOG4107QPN	acyl-Coa dehydrogenase
G6Z48_RS14625	ENOG4105CHR	reductase
G6Z48_RS14630	ENOG4105CC0	LysR family Transcriptional regulator
G6Z48_RS14640	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G6Z48_RS14645	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G6Z48_RS14655	ENOG4107QX8	SPFH domain, Band 7 family protein
G6Z48_RS14665	ENOG4105KK4	UPF0060 membrane protein
G6Z48_RS14670	ENOG4105DXN	mazG family
G6Z48_RS14675	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G6Z48_RS14680	ENOG4107RK2	ADP-ribose diphosphatase NudE
G6Z48_RS14690	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G6Z48_RS14710	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS14720	ENOG4105M3Z	response regulator
G6Z48_RS14725	ENOG4108UNF	response regulator
G6Z48_RS14730	ENOG4105D7Z	glutathione synthase
G6Z48_RS14740	ENOG41072GX	Peptidase M22 Glycoprotease
G6Z48_RS14745	ENOG4105DVT	helicase
G6Z48_RS14755	ENOG4105BZ4	penicillin-binding protein
G6Z48_RS14760	ENOG4108SHN	Glycosyl transferase, family 2
G6Z48_RS14775	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G6Z48_RS14785	ENOG4105CQ7	ATP-dependent helicase
G6Z48_RS14795	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G6Z48_RS14805	ENOG4105E3B	Multicopper oxidase
G6Z48_RS14995	ENOG4105CDU	Replicative dna helicase
G6Z48_RS15120	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G6Z48_RS15125	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G6Z48_RS15135	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G6Z48_RS15140	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G6Z48_RS15150	ENOG4105M8F	Biopolymer transport protein exbD tolR
G6Z48_RS15155	ENOG4105E02	MotA TolQ exbB proton channel
G6Z48_RS15160	ENOG4107YD3	Thioesterase
G6Z48_RS15165	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G6Z48_RS15170	ENOG4105DFH	Transport of potassium into the cell (By similarity)
G6Z48_RS15175	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G6Z48_RS15180	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G6Z48_RS15185	ENOG4105CDY	transcriptional regulatory protein
G6Z48_RS15205	ENOG4105C9M	aspartyl-trna synthetase
G6Z48_RS15230	ENOG4105ETT	transcriptional Regulator, LysR family
G6Z48_RS15235	ENOG4105C5H	ABC transporter
G6Z48_RS15260	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G6Z48_RS15270	ENOG4107EXC	regulatoR
G6Z48_RS15275	ENOG4105E0F	Histidine kinase
G6Z48_RS15285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G6Z48_RS15310	ENOG4105C7K	acetolactate synthase
G6Z48_RS15325	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS15330	ENOG4108K4C	ec 3.1.3.12
G6Z48_RS15335	ENOG4105BZP	glycoside hydrolase 15-related
G6Z48_RS15345	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
G6Z48_RS15360	ENOG4105C34	Pseudouridine synthase
G6Z48_RS15365	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6Z48_RS15375	ENOG4105C4K	Nad synthetase
G6Z48_RS15380	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G6Z48_RS15385	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G6Z48_RS15390	ENOG4107TUY	Histidine kinase
G6Z48_RS15395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6Z48_RS15400	ENOG4107QHF	type ii secretion system protein e
G6Z48_RS15405	ENOG4105X0D	Fimbrial protein
G6Z48_RS15420	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
G6Z48_RS15425	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G6Z48_RS15435	ENOG4105BZU	Histidine kinase
G6Z48_RS15440	ENOG4105ETX	regulatoR
G6Z48_RS15455	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G6Z48_RS15550	ENOG4107SUD	Esterase
G6Z48_RS15560	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G6Z48_RS15565	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G6Z48_RS15590	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G6Z48_RS15600	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G6Z48_RS15605	ENOG4105BZG	amino acid carrier protein
G6Z48_RS15615	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS15620	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS15635	ENOG4107R11	Transcriptional regulator
G6Z48_RS15645	ENOG4108UVJ	appr-1-p processing domain protein
G6Z48_RS15655	ENOG4107R1Y	fructose-bisphosphate aldolase
G6Z48_RS15660	ENOG4105CA9	Pyruvate kinase
G6Z48_RS15665	ENOG4107XGZ	Hydrolase
G6Z48_RS15670	ENOG4105BZA	Phosphoglycerate kinase
G6Z48_RS15685	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G6Z48_RS15690	ENOG4105EIF	outer membrane protein W
G6Z48_RS15715	ENOG4105NA0	Transcriptional regulator
G6Z48_RS15730	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G6Z48_RS15735	ENOG4105CK2	sodium dicarboxylate symporter
G6Z48_RS15765	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G6Z48_RS15770	ENOG4105E4G	Type IV pilus
G6Z48_RS15795	ENOG4108JQC	penicillin-binding protein 1A
G6Z48_RS15840	ENOG4105BZN	citrate synthase
G6Z48_RS15845	ENOG4105NRA	50s ribosomal protein l31 type b
G6Z48_RS15855	ENOG4105CB5	ATP-dependent DNA helicase recG
G6Z48_RS15860	ENOG4105KME	endoribonuclease L-psp
G6Z48_RS15865	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G6Z48_RS15870	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G6Z48_RS15885	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G6Z48_RS15890	ENOG4108MG3	formate dehydrogenase
G6Z48_RS15900	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
G6Z48_RS15905	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
G6Z48_RS15910	ENOG4105EM7	Selenocysteine-specific translation elongation factor
G6Z48_RS15920	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
G6Z48_RS15925	ENOG4105DSJ	YicC domain protein
G6Z48_RS15930	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G6Z48_RS15935	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6Z48_RS15940	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G6Z48_RS15945	ENOG4105CSA	Coproporphyrinogen iii oxidase
G6Z48_RS15960	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
G6Z48_RS15965	ENOG4107RAQ	aminopeptidase
G6Z48_RS15970	ENOG4105E07	UPF0149 protein
G6Z48_RS15980	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
G6Z48_RS15990	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G6Z48_RS16000	ENOG4105E66	phosphoriboisomerase A
G6Z48_RS16010	ENOG41063JG	Transcriptional regulator
G6Z48_RS16015	ENOG4105VCQ	rubredoxin
G6Z48_RS16020	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G6Z48_RS16025	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G6Z48_RS16030	ENOG41090JD	Blue (Type 1) copper domain protein
G6Z48_RS16040	ENOG4105C8Y	Acetylornithine aminotransferase
G6Z48_RS16045	ENOG4105EYW	Ion transport protein
G6Z48_RS16050	ENOG4108V87	frv operon regulatory protein
G6Z48_RS16055	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
G6Z48_RS16075	ENOG410841Q	phosphoesterase PA-phosphatase related protein
G6Z48_RS16085	ENOG4105DFU	Cell wall formation (By similarity)
G6Z48_RS16090	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G6Z48_RS16110	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G6Z48_RS16120	ENOG4108ZZF	transport protein (ExbD)
G6Z48_RS16130	ENOG4105WD1	Membrane
G6Z48_RS16135	ENOG4108YNN	Heme oxygenase
G6Z48_RS16145	ENOG4107ENK	receptor
G6Z48_RS16165	ENOG4105F0N	pyrophosphate phospho-hydrolase
G6Z48_RS16180	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS16185	ENOG4105ECQ	AraC Family Transcriptional Regulator
G6Z48_RS16200	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G6Z48_RS16205	ENOG4105C94	Transporter
G6Z48_RS16210	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G6Z48_RS16215	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G6Z48_RS16230	ENOG4105C7B	Threonine dehydratase
G6Z48_RS16235	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G6Z48_RS16255	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G6Z48_RS16270	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS16275	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G6Z48_RS16285	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G6Z48_RS16290	ENOG4105DFG	type I secretion outer membrane protein
G6Z48_RS16295	ENOG4105CUB	amino acid
G6Z48_RS16300	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G6Z48_RS16305	ENOG4105D1S	lipid A biosynthesis
G6Z48_RS16340	ENOG4105C6K	Malic enzyme
G6Z48_RS16345	ENOG4105CK2	sodium dicarboxylate symporter
G6Z48_RS16365	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
G6Z48_RS16370	ENOG4105DHQ	Histidine kinase
G6Z48_RS16385	ENOG4105D4T	Citrate transporter
G6Z48_RS16390	ENOG4105CHR	reductase
G6Z48_RS16410	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G6Z48_RS16415	ENOG4105CHM	Aminotransferase
G6Z48_RS16450	ENOG4105CI2	imidazolone-5-propionate hydrolase
G6Z48_RS16455	ENOG4105CQM	Urea amidohydrolase subunit alpha
G6Z48_RS16465	ENOG4108RMV	DegV Family
G6Z48_RS16475	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS16490	ENOG4105G2Y	Transcriptional regulator
G6Z48_RS16510	ENOG4105C4W	S-formylglutathione hydrolase
G6Z48_RS16540	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6Z48_RS16565	ENOG410642W	LysR family Transcriptional regulator
G6Z48_RS16570	ENOG4105DQ4	alcohol dehydrogenase
G6Z48_RS16590	ENOG4105CY0	Metallo-Beta-Lactamase
G6Z48_RS16595	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G6Z48_RS16600	ENOG4106RE7	Cytochrome
G6Z48_RS16605	ENOG4108Z33	Thiol disulfide Interchange Protein
G6Z48_RS16610	ENOG4108Z33	Thiol disulfide Interchange Protein
G6Z48_RS16635	ENOG4105CNM	Receptor
G6Z48_RS16660	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G6Z48_RS16700	ENOG4105CE4	GlcNAc 6-P deacetylase
G6Z48_RS16705	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G6Z48_RS16710	ENOG4107KJX	Transcriptional regulator
G6Z48_RS16720	ENOG4105CHC	glucokinase (EC 2.7.1.2)
G6Z48_RS16730	ENOG4105E2D	ec 3.2.1.52
G6Z48_RS16750	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6Z48_RS16775	ENOG4105BZU	Histidine kinase
G6Z48_RS16785	ENOG4105BZU	Histidine kinase
G6Z48_RS16790	ENOG4105W4M	Transport-associated protein
G6Z48_RS16795	ENOG4105D9R	oxidoreductase
G6Z48_RS16800	ENOG4108J5G	6-phosphogluconate dehydrogenase
G6Z48_RS16815	ENOG4105CN1	protease
G6Z48_RS16820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G6Z48_RS16840	ENOG4105DZ1	carboxypeptidase
G6Z48_RS16845	ENOG4105K6T	rare lipoprotein A
G6Z48_RS16850	ENOG4105CVE	Lytic murein transglycosylase
G6Z48_RS16855	ENOG4105CNI	cell division protein FtsW
G6Z48_RS16860	ENOG4105CNI	cell division protein FtsW
G6Z48_RS16875	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G6Z48_RS16885	ENOG4107T4Z	adenosine kinase
G6Z48_RS16900	ENOG4105CD8	aminopeptidase N
G6Z48_RS16905	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G6Z48_RS16930	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS16935	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS16940	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS16960	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G6Z48_RS16975	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G6Z48_RS16985	ENOG4105WD1	Membrane
G6Z48_RS17015	ENOG4108UMI	ABC transporter, permease
G6Z48_RS17020	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G6Z48_RS17025	ENOG4108EHX	EamA-like transporter family
G6Z48_RS17030	ENOG4108VPT	UPF0234 protein
G6Z48_RS17040	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
G6Z48_RS17045	ENOG4105DGW	oligopeptidase A
G6Z48_RS17055	ENOG4105C6T	cysteine synthase
G6Z48_RS17075	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G6Z48_RS17085	ENOG4105C19	ABC transporter
G6Z48_RS17090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G6Z48_RS17095	ENOG4107RBB	ABC transporter, permease
G6Z48_RS17105	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6Z48_RS17110	ENOG4105BZU	Histidine kinase
G6Z48_RS17120	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G6Z48_RS17130	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G6Z48_RS17135	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G6Z48_RS17140	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G6Z48_RS17145	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G6Z48_RS17150	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G6Z48_RS17155	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G6Z48_RS17160	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G6Z48_RS17165	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
G6Z48_RS17180	ENOG4107QN2	dihydrolipoyl dehydrogenase
G6Z48_RS17185	ENOG4107QSN	dihydrolipoamide acetyltransferase
G6Z48_RS17200	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G6Z48_RS17205	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G6Z48_RS17210	ENOG4105D01	(LipO)protein
G6Z48_RS17230	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G6Z48_RS17235	ENOG4108NEV	two component transcriptional regulator, LytTR family
G6Z48_RS17245	ENOG4106CJB	Phospholipase Carboxylesterase
G6Z48_RS17255	ENOG4105D05	Receptor
G6Z48_RS17265	ENOG4105NRM	Membrane
G6Z48_RS17290	ENOG4105C57	major facilitator superfamily
G6Z48_RS17335	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS17355	ENOG4105CYM	Glutathione S-transferase
G6Z48_RS17370	ENOG4108VBZ	doxx family
G6Z48_RS17390	ENOG410679B	prophage CP4-57 regulatory protein alpA
G6Z48_RS17500	ENOG4105KT5	UmuD protein
G6Z48_RS17505	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G6Z48_RS17850	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6Z48_RS17855	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G6Z48_RS17865	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
G6Z48_RS17890	ENOG4107T8Q	Glycosyl transferase (Group 1
G6Z48_RS17905	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G6Z48_RS17910	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G6Z48_RS17915	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G6Z48_RS17925	ENOG4105C79	DNA protecting protein DprA
G6Z48_RS17930	ENOG4108RPN	Protein smg homolog
G6Z48_RS17945	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G6Z48_RS17950	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G6Z48_RS17965	ENOG4107ZQV	short-chain dehydrogenase reductase
G6Z48_RS17975	ENOG4105D07	Signal peptide peptidase, SppA
G6Z48_RS17980	ENOG4107QI1	Mate efflux family protein
G6Z48_RS17995	ENOG4105C25	Primosomal protein n'
G6Z48_RS18000	ENOG4108TGY	Glutathione S-transferase
G6Z48_RS18025	ENOG41082IR	Excinuclease ABC C subunit domain protein
G6Z48_RS18030	ENOG4105EN6	Membrane
G6Z48_RS18035	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G6Z48_RS18055	ENOG41082F9	transcriptional regulator
G6Z48_RS18060	ENOG4105E0F	Histidine kinase
G6Z48_RS18085	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G6Z48_RS18090	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G6Z48_RS18095	ENOG4108K8S	endonuclease I
G6Z48_RS18100	ENOG4105VF7	tolerance protein
G6Z48_RS18105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
G6Z48_RS18110	ENOG4107QX9	Thiol disulfide interChange protein
G6Z48_RS18120	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS18125	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
G6Z48_RS18140	ENOG4105BZU	Histidine kinase
G6Z48_RS18160	ENOG4108PZW	LysR family Transcriptional regulator
G6Z48_RS18175	ENOG4105G6Z	alkaline phosphatase
G6Z48_RS18180	ENOG4105DZ1	carboxypeptidase
G6Z48_RS18190	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
G6Z48_RS18200	ENOG4105CR4	methylisocitrate lyase
G6Z48_RS18210	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G6Z48_RS18215	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G6Z48_RS18220	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G6Z48_RS18235	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G6Z48_RS18245	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G6Z48_RS18250	ENOG4108HPI	phosphatidate Cytidylyltransferase
G6Z48_RS18255	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
G6Z48_RS18265	ENOG41077RS	Phosphatase
G6Z48_RS18270	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
G6Z48_RS18275	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
G6Z48_RS18280	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G6Z48_RS18285	ENOG4105C12	Phosphoribosylglycinamide synthetase
G6Z48_RS18300	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6Z48_RS18305	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G6Z48_RS18310	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G6Z48_RS18315	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
G6Z48_RS18320	ENOG4105CAK	Cell division ATP-binding protein ftsE
G6Z48_RS18335	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G6Z48_RS18340	ENOG4105BZU	Histidine kinase
G6Z48_RS18350	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
G6Z48_RS18375	ENOG4105E9K	Isocitrate dehydrogenase
G6Z48_RS18385	ENOG4109066	lysm domain bon superfamily protein
G6Z48_RS18390	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G6Z48_RS18395	ENOG4105CH2	amidohydrolase
G6Z48_RS18400	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G6Z48_RS18405	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS18410	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS18415	ENOG4105EM2	membrane
G6Z48_RS18420	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
G6Z48_RS18425	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
G6Z48_RS18455	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
G6Z48_RS18480	ENOG4105BZU	Histidine kinase
G6Z48_RS18485	ENOG4108UQY	Iron-storage protein
G6Z48_RS18495	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G6Z48_RS18510	ENOG4108UJD	30S ribosomal protein S9
G6Z48_RS18515	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G6Z48_RS18525	ENOG4105KPY	Small multidrug resistance protein
G6Z48_RS18530	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G6Z48_RS18535	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
G6Z48_RS18540	ENOG410635A	Membrane
G6Z48_RS18550	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G6Z48_RS18555	ENOG4107QYG	anthranilate phosphoribosyltransferase
G6Z48_RS18560	ENOG4105DDQ	anthranilate synthase
G6Z48_RS18570	ENOG4105CRQ	synthase (Component I)
G6Z48_RS18575	ENOG4107TE5	Lipid kinase
G6Z48_RS18590	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
G6Z48_RS18595	ENOG4105C8V	SAICAR synthetase
G6Z48_RS18605	ENOG4105D65	subunit l
G6Z48_RS18610	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G6Z48_RS18615	ENOG4107R4Z	monovalent cation h antiporter subunit d
G6Z48_RS18620	ENOG4105SC1	monovalent cation H antiporter subunit E
G6Z48_RS18625	ENOG4105W4C	monovalent cation H antiporter subunit F
G6Z48_RS18630	ENOG4105KJM	monovalent cation h antiporter subunit g
G6Z48_RS18635	ENOG4105FEU	K -dependent Na -Ca exchanger
G6Z48_RS18655	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G6Z48_RS18665	ENOG4105DFS	Conserved Protein
G6Z48_RS18680	ENOG4105DUX	Transporter
G6Z48_RS18685	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
G6Z48_RS18690	ENOG4107RUY	(E1 component), alpha subunit
G6Z48_RS18705	ENOG4107QSN	dihydrolipoamide acetyltransferase
G6Z48_RS18715	ENOG4105D29	Helix-turn-helix type 11 domain protein
G6Z48_RS18725	ENOG4105BZU	Histidine kinase
G6Z48_RS18730	ENOG4105CKW	Inner membrane protein yedI
G6Z48_RS18735	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G6Z48_RS18740	ENOG4107RES	phosphoglycerol transferase I
G6Z48_RS18745	ENOG4105EGS	Mechanosensitive ion channel
G6Z48_RS18750	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS18765	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G6Z48_RS18785	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G6Z48_RS18805	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
G6Z48_RS18810	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
G6Z48_RS18825	ENOG4108YZA	Nitrogen regulatory protein pii
G6Z48_RS18830	ENOG4105W0Z	cytoplasmic protein
G6Z48_RS18905	ENOG4105C0P	Mg chelatase subunit ChlI
G6Z48_RS18915	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS18935	ENOG410667J	hydrolase
G6Z48_RS18940	ENOG4108TPP	exopolysaccharide synthesis
G6Z48_RS18970	ENOG4108ZX6	Electron transport protein SCO1 SenC
G6Z48_RS18975	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
G6Z48_RS18980	ENOG4105CCU	oxidase (Subunit III)
G6Z48_RS18985	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G6Z48_RS18990	ENOG4105E2S	oxidase) subunit II
G6Z48_RS18995	ENOG4107SQD	Transcriptional regulator, GntR family
G6Z48_RS19010	ENOG4107SQD	Transcriptional regulator, GntR family
G6Z48_RS19015	ENOG4105C3J	Cysteine desulfurase
G6Z48_RS19070	ENOG4105CRW	Short chain fatty acid transporter
G6Z48_RS19115	ENOG4105EPC	oxidoreductase
G6Z48_RS19130	ENOG4105E70	isomerase
G6Z48_RS19135	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
G6Z48_RS19140	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
G6Z48_RS19145	ENOG4105E98	transcriptional regulator DeoR family
G6Z48_RS19150	ENOG4105CE4	GlcNAc 6-P deacetylase
G6Z48_RS19155	ENOG4107QNK	)-transporter
G6Z48_RS19170	ENOG4105CKT	filamentous hemagglutinin
G6Z48_RS19190	ENOG4105MJ2	Competence protein
G6Z48_RS19210	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G6Z48_RS19215	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G6Z48_RS19220	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G6Z48_RS19225	ENOG4105CHR	reductase
G6Z48_RS19255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS19260	ENOG4105BZS	acriflavin resistance protein
G6Z48_RS19265	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6Z48_RS19270	ENOG4105EB3	Histidine kinase
G6Z48_RS19275	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G6Z48_RS19280	ENOG410756H	nucleotidyltransferase
G6Z48_RS19285	ENOG4108Z0R	Transferase
G6Z48_RS19310	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G6Z48_RS19325	ENOG4106032	Glutathionylspermidine synthase
G6Z48_RS19335	ENOG4105C01	Dihydroxy-acid dehydratase
G6Z48_RS19340	ENOG4105DVT	helicase
G6Z48_RS19350	ENOG4105E2X	shikimate dehydrogenase
G6Z48_RS19365	ENOG4105D52	delta-aminolevulinic acid dehydratase
G6Z48_RS19370	ENOG4105FFC	UPF0187 protein
G6Z48_RS19400	ENOG4105CYM	Glutathione S-transferase
G6Z48_RS19405	ENOG4108TEB	UPF0114 protein
G6Z48_RS19420	ENOG4105R1U	AraC Family Transcriptional Regulator
G6Z48_RS19435	ENOG4108IUW	ABC transporter
G6Z48_RS19465	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
G6Z48_RS19470	ENOG4105DA5	(ABC) transporter
G6Z48_RS19475	ENOG4105E3A	(ABC) transporter
G6Z48_RS19485	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
G6Z48_RS19495	ENOG4105F8V	Hydrolase, tatD family
G6Z48_RS19500	ENOG4105CQ7	ATP-dependent helicase
G6Z48_RS19510	ENOG4108R99	pseudouridine synthase
G6Z48_RS19525	ENOG4105CPC	Aldo Keto reductase
G6Z48_RS19540	ENOG4105E0Y	RtcB Protein
G6Z48_RS19555	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS19560	ENOG4105HEI	LysR family (Transcriptional regulator
G6Z48_RS19565	ENOG4105F27	Major Facilitator
G6Z48_RS19570	ENOG4105CV8	reductase
G6Z48_RS19575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G6Z48_RS19580	ENOG41082CH	UPF0145 protein
G6Z48_RS19585	ENOG4105CD5	CoA-binding domain protein
G6Z48_RS19590	ENOG4105CJW	magnesium transporter
G6Z48_RS19595	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G6Z48_RS19600	ENOG4107PTR	Ankyrin repeat
G6Z48_RS19605	ENOG4105VNG	YcgL domain-containing protein
G6Z48_RS19615	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G6Z48_RS19620	ENOG4105C2D	reductase
G6Z48_RS19660	ENOG4105C84	Histidine ammonia-lyase
G6Z48_RS19670	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
G6Z48_RS19690	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G6Z48_RS19705	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G6Z48_RS19710	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G6Z48_RS19720	ENOG4105EMN	RNA polymerase sigma factor
G6Z48_RS19755	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G6Z48_RS19765	ENOG4105H67	Protein of unknown function (DUF421)
G6Z48_RS19770	ENOG4105C2M	dna polymerase I
G6Z48_RS19805	ENOG4105C4R	Atp-dependent dna helicase
G6Z48_RS19815	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G6Z48_RS19820	ENOG4105W0E	50S ribosomal protein L33
G6Z48_RS19825	ENOG4105KDC	50s ribosomal protein l28
G6Z48_RS19835	ENOG4107RZZ	dna polymerase iii epsilon subunit
G6Z48_RS19845	ENOG4108UQ8	endoribonuclease L-psp
G6Z48_RS19880	ENOG4105CKK	Glycosyl transferase, family 2
G6Z48_RS19895	ENOG4105FA0	parb-like partition protein
G6Z48_RS19900	ENOG4107QJE	Chromosome Partitioning Protein
G6Z48_RS19905	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G6Z48_RS19925	ENOG4107RGH	Aldehyde dehydrogenase
G6Z48_RS19930	ENOG4105CSH	Transporter
G6Z48_RS19940	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G6Z48_RS19950	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
G6Z48_RS19955	ENOG4105BZU	Histidine kinase
G6Z48_RS19965	ENOG4105F7F	Chaperone
G6Z48_RS19975	ENOG4105MA0	exported protein
G6Z48_RS19980	ENOG4105CFU	surface antigen
G6Z48_RS19985	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G6Z48_RS19990	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
G6Z48_RS19995	ENOG4107QHF	type ii secretion system protein e
G6Z48_RS20000	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6Z48_RS20010	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G6Z48_RS20015	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G6Z48_RS20020	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G6Z48_RS20030	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G6Z48_RS20040	ENOG4105C8Q	Methyl-accepting chemotaxis
G6Z48_RS20095	ENOG4105DKK	Benzoate
G6Z48_RS20105	ENOG4105DSB	aldose 1-epimerase
G6Z48_RS20110	ENOG4105CVE	Lytic murein transglycosylase
G6Z48_RS20115	ENOG41067HS	methyltransferase
G6Z48_RS20125	ENOG4106TD9	Diguanylate cyclase
G6Z48_RS20155	ENOG4105EUJ	GTP cyclohydrolase i
G6Z48_RS20165	ENOG4105ZQC	membrane protein AaeX
G6Z48_RS20170	ENOG4105Y49	secretion protein, HlyD family
G6Z48_RS20175	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G6Z48_RS20180	ENOG4105DR8	Membrane
G6Z48_RS20195	ENOG4107QKA	exodeoxyribonuclease V beta
G6Z48_RS20200	ENOG4105DSY	exodeoxyribonuclease V, gamma
G6Z48_RS20205	ENOG4105DHJ	ABC, transporter
G6Z48_RS20210	ENOG4105CY3	ABC transporter, permease
G6Z48_RS20215	ENOG4107PE3	Mammalian cell entry related domain protein
G6Z48_RS20230	ENOG410903C	(LipO)protein
G6Z48_RS20235	ENOG4108V06	Glutathione peroxidase
G6Z48_RS20245	ENOG4107QSV	RmuC domain protein
G6Z48_RS20255	ENOG4105CIS	alcohol dehydrogenase
G6Z48_RS20280	ENOG4105CUB	amino acid
G6Z48_RS20290	ENOG4105DR4	Methyltransferase
G6Z48_RS20295	ENOG4105DU1	integral membrane protein, terc
G6Z48_RS20305	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
G6Z48_RS20320	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS20325	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G6Z48_RS20330	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G6Z48_RS20335	ENOG4105VG0	50S ribosomal protein l34
G6Z48_RS20340	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G6Z48_RS20345	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G6Z48_RS20350	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G6Z48_RS20355	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6Z48_RS20360	ENOG4108TYN	CAAX amino terminal protease family protein
G6Z48_RS20365	ENOG4108K0D	peptidase, M48
G6Z48_RS20395	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G6Z48_RS20445	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G6Z48_RS20450	ENOG4105CGF	Aromatic amino acid aminotransferase
G6Z48_RS20455	ENOG4105CHB	tonB-dependent Receptor
G6Z48_RS20475	ENOG4105DQE	DNA ligase
G6Z48_RS20490	ENOG4108UHU	Aldolase
G6Z48_RS20500	ENOG4105ETE	Transcriptional regulator (LacI family
G6Z48_RS20505	ENOG4105MIR	Phenylalanine 4-monooxygenase
G6Z48_RS20510	ENOG4105EW9	transcriptional regulator AsnC family
G6Z48_RS20515	ENOG4105D78	K07001 NTE family protein
G6Z48_RS20525	ENOG4107ZSV	Receptor
G6Z48_RS20545	ENOG4105DKW	ABC transporter
G6Z48_RS20560	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G6Z48_RS20565	ENOG4105DJ9	glucan biosynthesis protein
G6Z48_RS20570	ENOG4107104	thymidine kinase
G6Z48_RS20585	ENOG4105C4R	Atp-dependent dna helicase
G6Z48_RS20595	ENOG4108YXG	UPF0502 protein
G6Z48_RS20600	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
G6Z48_RS20605	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
G6Z48_RS20615	ENOG4105E55	glycerol-3-phosphate acyltransferase
G6Z48_RS20625	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G6Z48_RS20630	ENOG4105DH7	May be involved in recombination (By similarity)
G6Z48_RS20640	ENOG4108Z5K	methylglyoxal synthase
G6Z48_RS20645	ENOG4105BZU	Histidine kinase
G6Z48_RS20650	ENOG4105BZ8	glutamate synthase
G6Z48_RS20655	ENOG4105CBC	glutamate synthase
G6Z48_RS20675	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
G6Z48_RS20690	ENOG4108A04	Beta-lactamase
G6Z48_RS20715	ENOG4108I5C	dEAD DEAH box helicase
G6Z48_RS20750	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G6Z48_RS20770	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G6Z48_RS20780	ENOG4105CAF	HipA N-terminal domain protein
G6Z48_RS20800	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G6Z48_RS20820	ENOG4107RZC	phospholipase d
G6Z48_RS20825	ENOG4105KA0	thioesterase Superfamily protein
G6Z48_RS20830	ENOG4105E9Q	Acyl-transferase
G6Z48_RS20845	ENOG4108V1U	phospholipid-binding protein
G6Z48_RS20860	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G6Z48_RS20865	ENOG4105C5F	glutamine synthetase
G6Z48_RS20875	ENOG4105BZU	Histidine kinase
G6Z48_RS20880	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
G6Z48_RS20890	ENOG4105CA3	membrane-bound lytic murein transglycosylase
G6Z48_RS20905	ENOG4105CUX	Signal transduction histidine kinase
G6Z48_RS20910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6Z48_RS20915	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6Z48_RS20920	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6Z48_RS20930	ENOG4105CHU	acetyl-coa acetyltransferase
G6Z48_RS20965	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
G6Z48_RS20970	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G6Z48_RS20990	ENOG4105D6J	arsenicaL-resistance protein
G6Z48_RS21005	ENOG4105CAU	Arsenical resistance protein, ArsH
G6Z48_RS21055	ENOG4105D6J	arsenicaL-resistance protein
G6Z48_RS21070	ENOG4105CAU	Arsenical resistance protein, ArsH
G6Z48_RS21080	ENOG4105DB4	
G6Z48_RS21100	ENOG4105EZR	dyp-type peroxidase family protein
G6Z48_RS21140	ENOG41068CG	regulatoR
G6Z48_RS21145	ENOG4105BZU	Histidine kinase
G6Z48_RS21155	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G6Z48_RS21160	ENOG4105C1G	acyl-Coa dehydrogenase
G6Z48_RS21165	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G6Z48_RS21185	ENOG4105E2T	synthase III
G6Z48_RS21190	ENOG4108J2P	Alpha beta hydrolase fold
G6Z48_RS21200	ENOG410680H	amp-dependent synthetase and ligase
G6Z48_RS21205	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
G6Z48_RS21215	ENOG4105CPF	Cell wall formation (By similarity)
G6Z48_RS21225	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G6Z48_RS21240	ENOG4108PBI	Polysaccharide metabolism
G6Z48_RS21245	ENOG4107W19	lmbE family
G6Z48_RS21255	ENOG4105DR9	pseudouridine synthase
G6Z48_RS21265	ENOG4108YZN	class I peptide chain release factor
G6Z48_RS21275	ENOG4105DGW	oligopeptidase A
G6Z48_RS21290	ENOG4105C3F	Signal peptidase i
G6Z48_RS21295	ENOG4105D94	Major Facilitator Superfamily
G6Z48_RS21300	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS21305	ENOG4106NZI	LysR family Transcriptional regulator
G6Z48_RS21310	ENOG4107R11	Transcriptional regulator
G6Z48_RS21315	ENOG4107QP3	malate synthase g
G6Z48_RS21325	ENOG4105BZU	Histidine kinase
G6Z48_RS21350	ENOG4107QX3	carboxylase
G6Z48_RS21355	ENOG4105C1G	acyl-Coa dehydrogenase
G6Z48_RS21375	ENOG4108TZV	Membrane
G6Z48_RS21385	ENOG4105D6Z	AFG1 family ATPase
G6Z48_RS21390	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G6Z48_RS21395	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G6Z48_RS21415	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G6Z48_RS21420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6Z48_RS21435	ENOG4108RWI	nicotinamidase
G6Z48_RS21440	ENOG4105WPN	DNA integration recombination invertion protein
G6Z48_RS21455	ENOG4108SKZ	Patatin-like phospholipase
G6Z48_RS21465	ENOG4105CFF	transcriptional regulator
G6Z48_RS21470	ENOG4105C26	Dehydrogenase
G6Z48_RS21475	ENOG4105C1G	acyl-Coa dehydrogenase
G6Z48_RS21480	ENOG4105E39	Enoyl-CoA hydratase
G6Z48_RS21485	ENOG4108UKI	Enoyl-CoA hydratase
G6Z48_RS21490	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G6Z48_RS21495	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G6Z48_RS21520	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G6Z48_RS21530	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G6Z48_RS21535	ENOG4105EB3	Histidine kinase
G6Z48_RS21540	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
G6Z48_RS21550	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G6Z48_RS21555	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G6Z48_RS21570	ENOG4105VUH	addiction module killer protein
G6Z48_RS21615	ENOG4105VDW	Csbd family
G6Z48_RS21625	ENOG4105C31	Tryptophanyl-tRNA synthetase
G6Z48_RS21650	ENOG4105CSH	Transporter
G6Z48_RS21655	ENOG4105FDR	Membrane
G6Z48_RS21665	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G6Z48_RS21670	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G6Z48_RS21680	ENOG4105C19	ABC transporter
G6Z48_RS21700	ENOG4105BZU	Histidine kinase
G6Z48_RS21705	ENOG4108S01	response regulator
G6Z48_RS21720	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G6Z48_RS21735	ENOG4105C02	permease
G6Z48_RS21755	ENOG4105C0H	protease
G6Z48_RS21770	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
G6Z48_RS21785	ENOG4108KX4	response regulator
G6Z48_RS21805	ENOG4105C5Q	Transcriptional regulator
G6Z48_RS21810	ENOG4108W15	Protein of unknown function (DUF1456)
G6Z48_RS21820	ENOG4105EMU	Dehydrogenase
G6Z48_RS21830	ENOG4105C75	arginyL-tRNA synthetase
G6Z48_RS21835	ENOG4105W5Q	DNA repair protein (RadC
G6Z48_RS21840	ENOG41068CG	regulatoR
G6Z48_RS21845	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G6Z48_RS21850	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G6Z48_RS21855	ENOG4107QKV	phosphomannomutase
G6Z48_RS21865	ENOG4105C08	Histidine kinase
G6Z48_RS21875	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
G6Z48_RS21880	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
G6Z48_RS21895	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G6Z48_RS21900	ENOG4105CGK	Exodeoxyribonuclease III
G6Z48_RS21905	ENOG4105EYM	Major Facilitator superfamily
G6Z48_RS21915	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G6Z48_RS21920	ENOG4105DR5	peptidase
G6Z48_RS21925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G6Z48_RS21985	ENOG4107VAM	peptidase, m28
G6Z48_RS21995	ENOG41063SB	peptidase
G6Z48_RS22000	ENOG4105CN1	protease
G6Z48_RS22010	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
G6Z48_RS22015	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
G6Z48_RS22025	ENOG4105C26	Dehydrogenase
G6Z48_RS22050	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
G6Z48_RS22055	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
G6Z48_RS22080	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G6Z48_RS22090	ENOG4105DHU	Bile acid
G6Z48_RS22100	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G6Z48_RS22105	ENOG4107S2Z	UPF0761 membrane protein
G6Z48_RS22120	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G6Z48_RS22130	ENOG4107ZVW	dihydroneopterin aldolase
G6Z48_RS22135	ENOG4105CUY	Mechanosensitive ion channel
G6Z48_RS22140	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
G6Z48_RS22155	ENOG4108Z12	YiaAB two helix domain-containing protein
G6Z48_RS22165	ENOG4105D5Q	Arginine ornithine antiporter
G6Z48_RS22175	ENOG4106G6Q	Transcriptional regulator
G6Z48_RS22180	ENOG4105DTQ	mandelate racemase muconate lactonizing
G6Z48_RS22195	ENOG4108KPZ	tonB-dependent Receptor
G6Z48_RS22200	ENOG4107R6D	beta-lactam binding protein AmpH
G6Z48_RS22230	ENOG4105E32	cytoplasmic protein
G6Z48_RS22240	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G6Z48_RS22245	ENOG4105EX9	Membrane
G6Z48_RS22275	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
G6Z48_RS22280	ENOG4108YYC	ycei family
G6Z48_RS22295	ENOG4105Q26	Siderophore-interacting protein
G6Z48_RS22305	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G6Z48_RS22450	ENOG4105PGM	cation diffusion facilitator family transporter
G6Z48_RS22455	ENOG41090EM	Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter
G6Z48_RS22460	ENOG4108KQ5	Integrase catalytic subunit
G6Z48_RS22475	ENOG4105C5H	ABC transporter
G6Z48_RS22480	ENOG410642W	LysR family Transcriptional regulator
G6Z48_RS22485	ENOG4107S1E	Beta-lactamase
G6Z48_RS22490	ENOG4105F27	Major Facilitator
G6Z48_RS22495	ENOG41066DG	(EAL) domain protein
G6Z48_RS22505	ENOG4105E4C	Lytic transglycosylase catalytic
G6Z48_RS22530	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6Z48_RS22540	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
G6Z48_RS22545	ENOG4105CHP	RNA polymerase
G6Z48_RS22575	ENOG4108HRK	Histidine kinase
G6Z48_RS22580	ENOG4108VAC	response regulator
G6Z48_RS22600	ENOG4108IG5	Transcriptional regulator
G6Z48_RS22615	ENOG4105C9K	Endothelin-converting enzyme 1
G6Z48_RS22625	ENOG4105CC0	LysR family Transcriptional regulator
G6Z48_RS22635	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G6Z48_RS22640	ENOG4105EEQ	Na H antiporter
G6Z48_RS22665	ENOG4105ER2	Ompa motb domain protein
G6Z48_RS22670	ENOG4107RD7	Flagellar Motor Protein, MotA
G6Z48_RS22690	ENOG4105EW9	transcriptional regulator AsnC family
G6Z48_RS22695	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G6Z48_RS22700	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G6Z48_RS22710	ENOG4105BZU	Histidine kinase
G6Z48_RS22725	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
G6Z48_RS22730	ENOG4105I08	Pseudouridine synthase
G6Z48_RS22735	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
G6Z48_RS22745	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
G6Z48_RS22750	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G6Z48_RS22765	ENOG4105EJC	lysr family transcriptional regulator
G6Z48_RS22770	ENOG4108I0C	methyltransferase
G6Z48_RS22775	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G6Z48_RS22800	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G6Z48_RS22805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G6Z48_RS22810	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6Z48_RS22815	ENOG4108HSG	cytochrome biogenesis protein DipZ
G6Z48_RS22820	ENOG4105E0X	reductase
G6Z48_RS22825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6Z48_RS22830	ENOG4105BZU	Histidine kinase
G6Z48_RS22835	ENOG4105JJR	Histidine kinase
G6Z48_RS22840	ENOG4107EXC	regulatoR
G6Z48_RS22845	ENOG4105CAQ	asparagine synthetase
G6Z48_RS22855	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
G6Z48_RS22870	ENOG4105C1J	atp-dependent rna helicase
G6Z48_RS22880	ENOG4108RXX	maleylacetoacetate isomerase
G6Z48_RS22885	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G6Z48_RS22895	ENOG4105CZX	twitching motility protein
G6Z48_RS22920	ENOG4105C28	cystathionine
G6Z48_RS22930	ENOG4105EY8	ABC transporter
G6Z48_RS22935	ENOG4105EQK	-acetyltransferase
G6Z48_RS22945	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
G6Z48_RS22955	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G6Z48_RS22970	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6Z48_RS22975	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
G6Z48_RS22980	ENOG4108RG3	short-chain dehydrogenase reductase
G6Z48_RS23005	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
G6Z48_RS23025	ENOG4105CKK	Glycosyl transferase, family 2
G6Z48_RS23040	ENOG4105C10	Electron transfer flavoprotein
G6Z48_RS23045	ENOG4105BZJ	Electron transfer flavoprotein
G6Z48_RS23060	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G6Z48_RS23065	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
G6Z48_RS23080	ENOG4107QKV	phosphomannomutase
G6Z48_RS23085	ENOG4105C0D	helicase
G6Z48_RS23120	ENOG4105DHJ	ABC, transporter
G6Z48_RS23135	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS