locus-tag	class	description
DM611_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DM611_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DM611_RS00020	COG0187	DNA topoisomerase II activity
DM611_RS00025	COG1266	CAAX protease self-immunity
DM611_RS00030	COG0501	Belongs to the peptidase M48B family
DM611_RS00100	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DM611_RS00110	COG4772	TonB-dependent receptor
DM611_RS00145	COG0800	Aldolase
DM611_RS00160	COG3186	Phenylalanine-4-hydroxylase
DM611_RS00165	COG1522	sequence-specific DNA binding
DM611_RS00175	COG1752	Esterase of the alpha-beta hydrolase superfamily
DM611_RS00185	COG4771	TonB-dependent receptor
DM611_RS00205	COG1119	ATPase activity
DM611_RS00225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DM611_RS00230	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DM611_RS00240	COG0210	DNA helicase
DM611_RS00265	COG3132	Protein of unknown function, DUF480
DM611_RS00270	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DM611_RS00275	COG0284	orotidine-5'-phosphate decarboxylase activity
DM611_RS00285	COG2937	Belongs to the GPAT DAPAT family
DM611_RS00295	COG0037	tRNA processing
DM611_RS00300	COG2974	May be involved in recombination
DM611_RS00310	COG1803	Methylglyoxal synthase
DM611_RS00315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM611_RS00315	COG2205	protein histidine kinase activity
DM611_RS00320	COG0493	'glutamate synthase
DM611_RS00325	COG0067	glutamate synthase
DM611_RS00325	COG0070	glutamate synthase
DM611_RS00325	COG0069	glutamate synthase activity
DM611_RS00345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DM611_RS00360	COG2814	Major facilitator Superfamily
DM611_RS00425	COG0714	Associated with various cellular activities
DM611_RS00445	COG0312	modulator of DNA gyrase
DM611_RS00465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DM611_RS00485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DM611_RS00510	COG1881	PFAM PEBP family protein
DM611_RS00515	COG0431	NADPH-dependent FMN reductase
DM611_RS00525	COG1968	undecaprenyl-diphosphatase activity
DM611_RS00530	COG0174	glutamine synthetase
DM611_RS00535	COG0347	Belongs to the P(II) protein family
DM611_RS00540	COG0004	ammonium transporteR
DM611_RS00570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DM611_RS00580	COG3852	Histidine kinase
DM611_RS00585	COG2204	response regulator
DM611_RS00590	COG2032	superoxide dismutase activity
DM611_RS00595	COG2032	superoxide dismutase activity
DM611_RS00605	COG0183	Belongs to the thiolase family
DM611_RS00640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DM611_RS00645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DM611_RS00710	COG2837	iron assimilation
DM611_RS00740	COG2197	response regulator
DM611_RS00745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM611_RS00745	COG2205	protein histidine kinase activity
DM611_RS00750	COG3474	cytochrome
DM611_RS00760	COG1960	acyl-CoA dehydrogenase activity
DM611_RS00765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DM611_RS00775	COG0612	Peptidase, M16
DM611_RS00785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DM611_RS00790	COG0596	Alpha beta hydrolase
DM611_RS00800	COG0318	PFAM AMP-dependent synthetase and ligase
DM611_RS00805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DM611_RS00815	COG1181	Belongs to the D-alanine--D-alanine ligase family
DM611_RS00825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DM611_RS00855	COG0339	signal peptide processing
DM611_RS00870	COG0681	Belongs to the peptidase S26 family
DM611_RS00875	COG2814	Major facilitator Superfamily
DM611_RS00880	COG0583	DNA-binding transcription factor activity
DM611_RS00895	COG0583	DNA-binding transcription factor activity
DM611_RS00900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DM611_RS00905	COG2224	Isocitrate lyase
DM611_RS00910	COG3706	GGDEF domain
DM611_RS00935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DM611_RS00940	COG1960	acyl-CoA dehydrogenase activity
DM611_RS00960	COG0697	spore germination
DM611_RS00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DM611_RS00990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DM611_RS01000	COG1280	lysine exporter protein (LysE YggA)
DM611_RS01005	COG1607	acyl-coa hydrolase
DM611_RS01015	COG1902	pentaerythritol trinitrate reductase activity
DM611_RS01030	COG1335	isochorismatase
DM611_RS01035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DM611_RS01045	COG1056	cytidyltransferase-related domain
DM611_RS01045	COG1051	belongs to the nudix hydrolase family
DM611_RS01050	COG1752	Esterase of the alpha-beta hydrolase superfamily
DM611_RS01065	COG3800	Transcriptional regulator
DM611_RS01065	COG1396	sequence-specific DNA binding
DM611_RS01075	COG1960	acyl-CoA dehydrogenase activity
DM611_RS01080	COG1024	Enoyl-CoA hydratase
DM611_RS01085	COG1024	Enoyl-CoA hydratase
DM611_RS01095	COG1764	response to oxidative stress
DM611_RS01105	COG0659	secondary active sulfate transmembrane transporter activity
DM611_RS01115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DM611_RS01140	COG3228	Belongs to the MtfA family
DM611_RS01150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DM611_RS01150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DM611_RS01155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DM611_RS01220	COG3237	CsbD-like
DM611_RS01230	COG0180	Tryptophanyl-tRNA synthetase
DM611_RS01255	COG0477	Major facilitator Superfamily
DM611_RS01260	COG0697	spore germination
DM611_RS01270	COG4206	TonB-dependent receptor
DM611_RS01280	COG1136	(ABC) transporter
DM611_RS01280	COG0577	efflux transmembrane transporter activity
DM611_RS01290	COG1136	(ABC) transporter
DM611_RS01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS01310	COG4585	Histidine kinase
DM611_RS01315	COG2197	response regulator
DM611_RS01330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DM611_RS01335	COG0546	phosphoglycolate phosphatase activity
DM611_RS01340	COG0628	permease
DM611_RS01360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM611_RS01375	COG5507	3-demethylubiquinone-9 3-methyltransferase
DM611_RS01400	COG2814	Major facilitator Superfamily
DM611_RS01405	COG0583	DNA-binding transcription factor activity
DM611_RS01410	COG4807	Protein conserved in bacteria
DM611_RS01415	COG4221	oxidoreductase activity
DM611_RS01425	COG0018	arginyl-trna synthetase
DM611_RS01430	COG2003	Belongs to the UPF0758 family
DM611_RS01435	COG2197	response regulator
DM611_RS01440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DM611_RS01445	COG0756	dUTP diphosphatase activity
DM611_RS01460	COG2205	protein histidine kinase activity
DM611_RS01470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DM611_RS01475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DM611_RS01490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DM611_RS01495	COG0708	Exodeoxyribonuclease III
DM611_RS01500	COG2223	nitrite transmembrane transporter activity
DM611_RS01515	COG0739	heme binding
DM611_RS01580	COG2234	aminopeptidase activity
DM611_RS01590	COG4942	peptidase
DM611_RS01595	COG0793	Belongs to the peptidase S41A family
DM611_RS01610	COG2067	long-chain fatty acid transport protein
DM611_RS01635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DM611_RS01680	COG0109	protoheme IX farnesyltransferase activity
DM611_RS01700	COG0358	DNA primase activity
DM611_RS01705	COG1295	ribonuclease BN
DM611_RS01725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DM611_RS01735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DM611_RS01740	COG0668	transmembrane transport
DM611_RS01755	COG2133	pyrroloquinoline quinone binding
DM611_RS01760	COG4682	membrane
DM611_RS01770	COG0531	amino acid
DM611_RS01780	COG1737	Transcriptional regulator
DM611_RS01785	COG4948	Mandelate Racemase Muconate Lactonizing
DM611_RS01810	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DM611_RS01845	COG5383	Protein conserved in bacteria
DM611_RS01855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DM611_RS01860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DM611_RS01885	COG0778	Nitroreductase
DM611_RS01890	COG2353	YceI-like domain
DM611_RS01905	COG2375	cellular response to nickel ion
DM611_RS01980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DM611_RS02040	COG2267	carboxylic ester hydrolase activity
DM611_RS02095	COG0488	(ABC) transporter
DM611_RS02100	COG0583	DNA-binding transcription factor activity
DM611_RS02110	COG2814	Major facilitator Superfamily
DM611_RS02115	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DM611_RS02120	COG1113	amino acid transport
DM611_RS02125	COG0741	lytic transglycosylase activity
DM611_RS02150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DM611_RS02160	COG5507	3-demethylubiquinone-9 3-methyltransferase
DM611_RS02165	COG4941	Belongs to the sigma-70 factor family
DM611_RS02175	COG3275	phosphorelay sensor kinase activity
DM611_RS02180	COG3279	Response regulator of the LytR AlgR family
DM611_RS02200	COG1309	transcriptional regulator
DM611_RS02210	COG2814	Major facilitator Superfamily
DM611_RS02215	COG3590	peptidase
DM611_RS02220	COG5001	Diguanylate cyclase
DM611_RS02225	COG0583	DNA-binding transcription factor activity
DM611_RS02235	COG3384	dioxygenase
DM611_RS02240	COG0025	NhaP-type Na H and K H
DM611_RS02265	COG1360	Flagellar Motor Protein
DM611_RS02295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM611_RS02310	COG5002	protein histidine kinase activity
DM611_RS02325	COG2813	Specifically methylates the guanine in position
DM611_RS02330	COG1187	pseudouridine synthase activity
DM611_RS02335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM611_RS02345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DM611_RS02350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DM611_RS02370	COG0583	DNA-binding transcription factor activity
DM611_RS02375	COG2226	methyltransferase
DM611_RS02405	COG1956	GAF domain-containing protein
DM611_RS02410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DM611_RS02425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM611_RS02430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DM611_RS02435	COG0785	Cytochrome C biogenesis protein
DM611_RS02435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM611_RS02440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DM611_RS02445	COG0745	RESPONSE REGULATOR receiver
DM611_RS02450	COG5002	protein histidine kinase activity
DM611_RS02455	COG2205	protein histidine kinase activity
DM611_RS02460	COG0745	RESPONSE REGULATOR receiver
DM611_RS02465	COG0367	asparagine synthase
DM611_RS02475	COG0720	synthase
DM611_RS02490	COG0513	Belongs to the DEAD box helicase family
DM611_RS02500	COG0625	glutathione transferase activity
DM611_RS02560	COG0626	cystathionine gamma-synthase activity
DM611_RS02595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DM611_RS02625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DM611_RS02630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DM611_RS02665	COG1127	ABC transporter
DM611_RS02670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM611_RS02685	COG0442	prolyl-tRNA aminoacylation
DM611_RS02700	COG1183	phosphatidylcholine synthase activity
DM611_RS02710	COG0456	acetyltransferase
DM611_RS02720	COG0525	valine-tRNA ligase activity
DM611_RS02735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DM611_RS02745	COG0795	lipopolysaccharide-transporting ATPase activity
DM611_RS02760	COG4974	Belongs to the 'phage' integrase family
DM611_RS02765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DM611_RS02780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM611_RS02780	COG0047	phosphoribosylformylglycinamidine synthase activity
DM611_RS02785	COG5295	Hep Hag repeat protein
DM611_RS02790	COG1404	Belongs to the peptidase S8 family
DM611_RS02795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DM611_RS02800	COG1459	type II secretion system
DM611_RS02805	COG2165	general secretion pathway protein
DM611_RS02810	COG4970	Tfp pilus assembly protein FimT
DM611_RS02815	COG2165	general secretion pathway protein
DM611_RS02820	COG4795	General secretion pathway protein
DM611_RS02825	COG3156	type II secretion system protein K
DM611_RS02830	COG3166	PFAM Fimbrial assembly family protein
DM611_RS02845	COG1450	Type ii and iii secretion system protein
DM611_RS02870	COG3539	Fimbrial protein
DM611_RS02875	COG3121	Chaperone
DM611_RS02890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DM611_RS02900	COG1215	transferase activity, transferring glycosyl groups
DM611_RS02915	COG2252	PERMEase
DM611_RS02920	COG0488	(ABC) transporter
DM611_RS02930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DM611_RS02945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DM611_RS02950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM611_RS02950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM611_RS03010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DM611_RS03015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM611_RS03030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DM611_RS03030	COG2755	lipolytic protein G-D-S-L family
DM611_RS03035	COG0277	FAD linked oxidase domain protein
DM611_RS03040	COG1988	membrane-bound metal-dependent
DM611_RS03075	COG2001	Belongs to the MraZ family
DM611_RS03080	COG0275	rRNA processing
DM611_RS03085	COG3116	cell division
DM611_RS03095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DM611_RS03100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DM611_RS03120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DM611_RS03125	COG1181	Belongs to the D-alanine--D-alanine ligase family
DM611_RS03130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DM611_RS03140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DM611_RS03145	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DM611_RS03155	COG0739	heme binding
DM611_RS03160	COG0653	protein targeting
DM611_RS03165	COG0494	nUDIX hydrolase
DM611_RS03175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DM611_RS03185	COG3275	phosphorelay sensor kinase activity
DM611_RS03195	COG0402	S-adenosylhomocysteine deaminase activity
DM611_RS03215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DM611_RS03220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DM611_RS03230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DM611_RS03240	COG1607	acyl-coa hydrolase
DM611_RS03245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DM611_RS03265	COG4106	trans-aconitate 2-methyltransferase activity
DM611_RS03270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DM611_RS03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM611_RS03295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DM611_RS03300	COG0667	Aldo Keto reductase
DM611_RS03310	COG4771	TonB-dependent receptor
DM611_RS03330	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DM611_RS03335	COG4181	ATPase activity
DM611_RS03350	COG0642	Histidine kinase
DM611_RS03360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DM611_RS03365	COG0861	Integral membrane protein TerC family
DM611_RS03370	COG2814	Major facilitator Superfamily
DM611_RS03375	COG1704	LemA family
DM611_RS03390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DM611_RS03395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DM611_RS03405	COG3738	Protein conserved in bacteria
DM611_RS03410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DM611_RS03415	COG2967	ApaG domain
DM611_RS03420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DM611_RS03425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DM611_RS03430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM611_RS03435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DM611_RS03445	COG2096	Adenosyltransferase
DM611_RS03455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS03460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS03470	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DM611_RS03490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM611_RS03500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DM611_RS03510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DM611_RS03515	COG0583	DNA-binding transcription factor activity
DM611_RS03520	COG3634	alkyl hydroperoxide reductase activity
DM611_RS03580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DM611_RS03605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DM611_RS03620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DM611_RS03625	COG1404	Belongs to the peptidase S8 family
DM611_RS03645	COG1295	ribonuclease BN
DM611_RS03650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM611_RS03665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DM611_RS03670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DM611_RS03685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DM611_RS03695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DM611_RS03700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DM611_RS03705	COG0193	aminoacyl-tRNA hydrolase activity
DM611_RS03710	COG0012	GTP binding
DM611_RS03720	COG2197	response regulator
DM611_RS03725	COG0784	Response regulator, receiver
DM611_RS03725	COG2205	protein histidine kinase activity
DM611_RS03730	COG2203	Gaf domain
DM611_RS03730	COG5001	Diguanylate cyclase
DM611_RS03730	COG4251	negative regulation of phosphorylation
DM611_RS03730	COG3706	GGDEF domain
DM611_RS03735	COG2205	protein histidine kinase activity
DM611_RS03735	COG0784	Response regulator, receiver
DM611_RS03740	COG4206	TonB-dependent receptor
DM611_RS03745	COG4242	Belongs to the peptidase S51 family
DM611_RS03770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DM611_RS03785	COG0250	Participates in transcription elongation, termination and antitermination
DM611_RS03790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DM611_RS03795	COG0081	regulation of translation
DM611_RS03805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DM611_RS03810	COG0222	ribosome binding
DM611_RS03815	COG0085	RNA polymerase activity
DM611_RS03820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DM611_RS03825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DM611_RS03830	COG0049	tRNA binding
DM611_RS03835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DM611_RS03840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DM611_RS03845	COG0051	transcription antitermination factor activity, RNA binding
DM611_RS03850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DM611_RS03855	COG0088	Forms part of the polypeptide exit tunnel
DM611_RS03860	COG0089	rRNA binding
DM611_RS03865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DM611_RS03870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DM611_RS03875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DM611_RS03880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DM611_RS03885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DM611_RS03890	COG0255	Belongs to the universal ribosomal protein uL29 family
DM611_RS03895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DM611_RS03900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DM611_RS03905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DM611_RS03910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DM611_RS03915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DM611_RS03920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DM611_RS03925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DM611_RS03930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DM611_RS03935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DM611_RS03940	COG1841	ribosomal large subunit assembly
DM611_RS03945	COG0200	Binds to the 23S rRNA
DM611_RS03950	COG0201	protein transport
DM611_RS03955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DM611_RS03960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DM611_RS03965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DM611_RS03970	COG0202	RNA polymerase activity
DM611_RS03975	COG0203	ribosomal protein L17
DM611_RS03990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DM611_RS04005	COG0154	amidase activity
DM611_RS04025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DM611_RS04030	COG0039	L-malate dehydrogenase activity
DM611_RS04035	COG0564	pseudouridine synthase activity
DM611_RS04045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DM611_RS04060	COG0625	glutathione transferase activity
DM611_RS04070	COG1902	pentaerythritol trinitrate reductase activity
DM611_RS04070	COG0446	pyridine nucleotide-disulphide oxidoreductase
DM611_RS04075	COG2364	Membrane
DM611_RS04095	COG1187	pseudouridine synthase activity
DM611_RS04115	COG1063	alcohol dehydrogenase
DM611_RS04125	COG0588	phosphoglycerate mutase activity
DM611_RS04130	COG0285	dihydrofolate synthase activity
DM611_RS04150	COG2833	Protein of unknown function (DUF455)
DM611_RS04160	COG3291	Pkd domain containing protein
DM611_RS04165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DM611_RS04170	COG0671	phosphoesterase, PA-phosphatase related
DM611_RS04175	COG0438	transferase activity, transferring glycosyl groups
DM611_RS04180	COG0248	Ppx GppA phosphatase
DM611_RS04190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DM611_RS04205	COG4783	chaperone-mediated protein folding
DM611_RS04220	COG0473	3-isopropylmalate dehydrogenase activity
DM611_RS04285	COG0544	peptidyl-prolyl cis-trans isomerase activity
DM611_RS04290	COG0740	serine-type endopeptidase activity
DM611_RS04295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DM611_RS04335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM611_RS04340	COG1388	LysM domain
DM611_RS04340	COG3942	CHAP domain
DM611_RS04345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM611_RS04355	COG0328	RNA-DNA hybrid ribonuclease activity
DM611_RS04360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DM611_RS04365	COG0631	protein serine/threonine phosphatase activity
DM611_RS04380	COG0859	PFAM glycosyl transferase family 9
DM611_RS04385	COG3642	lipopolysaccharide core region biosynthetic process
DM611_RS04390	COG1234	tRNA 3'-trailer cleavage
DM611_RS04405	COG2076	Multidrug Resistance protein
DM611_RS04430	COG3209	COG3209 Rhs family protein
DM611_RS04465	COG4695	Portal protein
DM611_RS04485	COG0582	viral genome integration into host DNA
DM611_RS04500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DM611_RS04530	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DM611_RS04560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DM611_RS04565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DM611_RS04575	COG0537	adenosine 5'-monophosphoramidase activity
DM611_RS04595	COG0714	Associated with various cellular activities
DM611_RS04610	COG1399	metal-binding, possibly nucleic acid-binding protein
DM611_RS04615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DM611_RS04620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DM611_RS04630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DM611_RS04645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DM611_RS04650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DM611_RS04655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DM611_RS04660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DM611_RS04825	COG4774	siderophore transport
DM611_RS04835	COG2223	nitrite transmembrane transporter activity
DM611_RS04850	COG2226	methyltransferase
DM611_RS04860	COG0583	DNA-binding transcription factor activity
DM611_RS04865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM611_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS04880	COG0583	DNA-binding transcription factor activity
DM611_RS04890	COG0477	Major facilitator Superfamily
DM611_RS04895	COG2205	protein histidine kinase activity
DM611_RS04945	COG0583	DNA-binding transcription factor activity
DM611_RS04955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DM611_RS04975	COG0667	Aldo Keto reductase
DM611_RS05000	COG2818	Glycosylase
DM611_RS05005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DM611_RS05010	COG1678	Uncharacterized ACR, COG1678
DM611_RS05015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DM611_RS05020	COG0540	Belongs to the ATCase OTCase family
DM611_RS05045	COG2239	Acts as a magnesium transporter
DM611_RS05050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM611_RS05065	COG1660	Displays ATPase and GTPase activities
DM611_RS05070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DM611_RS05075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM611_RS05080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DM611_RS05090	COG1137	ATPase activity
DM611_RS05105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DM611_RS05120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DM611_RS05140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DM611_RS05160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DM611_RS05170	COG0628	permease
DM611_RS05185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DM611_RS05195	COG2261	transglycosylase associated protein
DM611_RS05205	COG1555	photosystem II stabilization
DM611_RS05230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DM611_RS05235	COG1477	protein flavinylation
DM611_RS05255	COG4771	TonB-dependent receptor
DM611_RS05265	COG3128	pkhd-type hydroxylase
DM611_RS05295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DM611_RS05300	COG0719	Fe-S assembly protein
DM611_RS05305	COG0396	ATPase activity
DM611_RS05310	COG0719	Fe-S assembly protein
DM611_RS05315	COG1959	2 iron, 2 sulfur cluster binding
DM611_RS05345	COG1764	response to oxidative stress
DM611_RS05350	COG0384	phenazine biosynthesis protein PhzF
DM611_RS05355	COG0384	phenazine biosynthesis protein PhzF
DM611_RS05360	COG0527	aspartate kinase activity
DM611_RS05370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DM611_RS05385	COG0142	geranyltranstransferase activity
DM611_RS05390	COG0366	Alpha amylase catalytic
DM611_RS05400	COG1082	Xylose isomerase domain protein TIM barrel
DM611_RS05410	COG2211	Major facilitator Superfamily
DM611_RS05410	COG2190	(PTS) system
DM611_RS05445	COG1131	(ABC) transporter
DM611_RS05450	COG1609	Transcriptional regulator
DM611_RS05460	COG0629	single-stranded DNA binding
DM611_RS05485	COG2010	Cytochrome c
DM611_RS05495	COG0673	inositol 2-dehydrogenase activity
DM611_RS05500	COG2211	Major facilitator Superfamily
DM611_RS05510	COG1609	Transcriptional regulator
DM611_RS05555	COG0583	DNA-binding transcription factor activity
DM611_RS05560	COG1073	alpha beta
DM611_RS05565	COG1073	alpha beta
DM611_RS05575	COG0640	Transcriptional regulator
DM611_RS05585	COG3655	Transcriptional regulator
DM611_RS05590	COG1253	flavin adenine dinucleotide binding
DM611_RS05595	COG1408	metallophosphoesterase
DM611_RS05610	COG0477	Major facilitator Superfamily
DM611_RS05625	COG1802	Transcriptional regulator
DM611_RS05665	COG3052	prosthetic group binding
DM611_RS05680	COG0579	oxidoreductase
DM611_RS05715	COG3104	oligopeptide transport
DM611_RS05720	COG1297	OPT oligopeptide transporter protein
DM611_RS05725	COG0823	Involved in the tonB-independent uptake of proteins
DM611_RS05725	COG1506	peptidase
DM611_RS05740	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DM611_RS05745	COG2894	cell division
DM611_RS05760	COG4585	Histidine kinase
DM611_RS05765	COG2197	response regulator
DM611_RS05805	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DM611_RS05820	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DM611_RS05830	COG1595	DNA-templated transcription, initiation
DM611_RS05840	COG1946	Acyl-CoA thioesterase
DM611_RS05860	COG0824	Thioesterase
DM611_RS05865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DM611_RS05870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DM611_RS05875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DM611_RS05880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DM611_RS05885	COG0268	Binds directly to 16S ribosomal RNA
DM611_RS05890	COG0728	peptidoglycan biosynthetic process
DM611_RS05895	COG0196	riboflavin kinase activity
DM611_RS05900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DM611_RS05910	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DM611_RS05925	COG4206	TonB-dependent receptor
DM611_RS05945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM611_RS06030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DM611_RS06035	COG1845	cytochrome c oxidase, subunit III
DM611_RS06040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DM611_RS06055	COG0326	Molecular chaperone. Has ATPase activity
DM611_RS06075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DM611_RS06095	COG0228	four-way junction DNA binding
DM611_RS06100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DM611_RS06105	COG0336	Belongs to the RNA methyltransferase TrmD family
DM611_RS06110	COG0335	large ribosomal subunit rRNA binding
DM611_RS06130	COG0534	Mate efflux family protein
DM611_RS06150	COG0753	catalase activity
DM611_RS06175	COG0840	transmembrane signaling receptor activity
DM611_RS06180	COG3134	Outer membrane lipoprotein
DM611_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS06215	COG0024	Methionine aminopeptidase
DM611_RS06240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DM611_RS06265	COG1647	Serine aminopeptidase, S33
DM611_RS06290	COG2814	Major facilitator Superfamily
DM611_RS06295	COG3706	GGDEF domain
DM611_RS06315	COG0588	phosphoglycerate mutase activity
DM611_RS06320	COG3590	peptidase
DM611_RS06330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DM611_RS06340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DM611_RS06345	COG0745	RESPONSE REGULATOR receiver
DM611_RS06350	COG2205	protein histidine kinase activity
DM611_RS06355	COG4452	Inner membrane protein CreD
DM611_RS06370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM611_RS06375	COG0735	belongs to the Fur family
DM611_RS06425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DM611_RS06465	COG5001	Diguanylate cyclase
DM611_RS06465	COG5002	protein histidine kinase activity
DM611_RS06475	COG1187	pseudouridine synthase activity
DM611_RS06485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DM611_RS06510	COG1132	(ABC) transporter
DM611_RS06570	COG1695	Transcriptional regulator
DM611_RS06590	COG1981	membrane
DM611_RS06595	COG0825	malonyl-CoA metabolic process
DM611_RS06620	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DM611_RS06630	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DM611_RS06635	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM611_RS06640	COG0750	zinc metalloprotease
DM611_RS06645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DM611_RS06650	COG0575	Belongs to the CDS family
DM611_RS06655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DM611_RS06660	COG0233	cytoplasmic translational termination
DM611_RS06665	COG0528	UMP kinase activity
DM611_RS06675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DM611_RS06680	COG0052	Belongs to the universal ribosomal protein uS2 family
DM611_RS06700	COG3188	usher protein
DM611_RS06720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DM611_RS06735	COG1393	Belongs to the ArsC family
DM611_RS06740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DM611_RS06750	COG0367	asparagine synthase
DM611_RS06755	COG0475	glutathione-regulated potassium exporter activity
DM611_RS06790	COG1566	PFAM secretion protein HlyD family protein
DM611_RS06795	COG2814	Major facilitator Superfamily
DM611_RS06805	COG0583	DNA-binding transcription factor activity
DM611_RS06825	COG0557	exoribonuclease II activity
DM611_RS06835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM611_RS06840	COG1538	Outer membrane efflux protein
DM611_RS06845	COG0577	efflux transmembrane transporter activity
DM611_RS06845	COG1136	(ABC) transporter
DM611_RS06850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS06870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DM611_RS06875	COG2259	Doxx family
DM611_RS06885	COG3220	belongs to the UPF0276 family
DM611_RS06895	COG0704	Plays a role in the regulation of phosphate uptake
DM611_RS06905	COG0581	inorganic phosphate transmembrane transporter activity
DM611_RS06910	COG0573	inorganic phosphate transmembrane transporter activity
DM611_RS06915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM611_RS06925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM611_RS06935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DM611_RS06945	COG1024	Enoyl-CoA hydratase
DM611_RS06955	COG0494	nUDIX hydrolase
DM611_RS06975	COG0116	Belongs to the methyltransferase superfamily
DM611_RS06975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DM611_RS06995	COG2733	membrane
DM611_RS07005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DM611_RS07010	COG1012	belongs to the aldehyde dehydrogenase family
DM611_RS07020	COG0477	Major facilitator Superfamily
DM611_RS07025	COG2703	oxygen carrier activity
DM611_RS07050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM611_RS07060	COG0174	glutamine synthetase
DM611_RS07070	COG2072	flavoprotein involved in K transport
DM611_RS07075	COG3842	ATPase activity
DM611_RS07080	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM611_RS07085	COG1177	transmembrane transport
DM611_RS07090	COG1012	belongs to the aldehyde dehydrogenase family
DM611_RS07105	COG4535	Mg2 and Co2 transporter CorC
DM611_RS07120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DM611_RS07125	COG1702	phosphate starvation-inducible protein PhoH
DM611_RS07135	COG1131	(ABC) transporter
DM611_RS07140	COG0842	Transport permease protein
DM611_RS07145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DM611_RS07160	COG0741	lytic transglycosylase activity
DM611_RS07165	COG0723	plastoquinol--plastocyanin reductase activity
DM611_RS07170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DM611_RS07175	COG2857	Cytochrome c1
DM611_RS07180	COG0625	glutathione transferase activity
DM611_RS07185	COG2969	positive regulation of protein catabolic process
DM611_RS07220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM611_RS07230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DM611_RS07245	COG1611	Belongs to the LOG family
DM611_RS07290	COG0556	nucleotide-excision repair
DM611_RS07325	COG3713	MltA-interacting MipA family protein
DM611_RS07340	COG2333	competence protein COMEC
DM611_RS07340	COG0658	competence protein
DM611_RS07345	COG0811	peptide transport
DM611_RS07360	COG1663	tetraacyldisaccharide 4'-kinase activity
DM611_RS07365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DM611_RS07370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DM611_RS07380	COG0322	excinuclease ABC activity
DM611_RS07415	COG1136	(ABC) transporter
DM611_RS07415	COG0577	efflux transmembrane transporter activity
DM611_RS07465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DM611_RS07490	COG0583	DNA-binding transcription factor activity
DM611_RS07515	COG1917	Cupin 2, conserved barrel domain protein
DM611_RS07515	COG4977	sequence-specific DNA binding
DM611_RS07520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DM611_RS07540	COG0348	domain, Protein
DM611_RS07555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM611_RS07580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DM611_RS07585	COG0069	glutamate synthase activity
DM611_RS07615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DM611_RS07630	COG1253	flavin adenine dinucleotide binding
DM611_RS07665	COG0504	CTP synthase activity
DM611_RS07670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DM611_RS07685	COG0148	phosphopyruvate hydratase activity
DM611_RS07690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DM611_RS07695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DM611_RS07700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DM611_RS07710	COG2840	Smr protein MutS2
DM611_RS07715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DM611_RS07720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DM611_RS07730	COG4942	peptidase
DM611_RS07730	COG1388	LysM domain
DM611_RS07745	COG1534	Rna-binding protein
DM611_RS07750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DM611_RS07755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DM611_RS07765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DM611_RS07770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DM611_RS07775	COG1923	regulation of RNA biosynthetic process
DM611_RS07780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DM611_RS07785	COG1546	Belongs to the CinA family
DM611_RS07790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DM611_RS07795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DM611_RS07800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DM611_RS07805	COG2137	regulation of response to DNA damage stimulus
DM611_RS07810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DM611_RS07815	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DM611_RS07890	COG2204	response regulator
DM611_RS07895	COG4191	Histidine kinase
DM611_RS07895	COG0784	Response regulator, receiver
DM611_RS07910	COG3685	Protein conserved in bacteria
DM611_RS07940	COG3685	Protein conserved in bacteria
DM611_RS07950	COG0745	RESPONSE REGULATOR receiver
DM611_RS08035	COG1475	DNA binding
DM611_RS08080	COG1940	carbohydrate kinase activity
DM611_RS08120	COG3540	Alkaline phosphatase
DM611_RS08140	COG3258	Cytochrome c
DM611_RS08155	COG2223	nitrite transmembrane transporter activity
DM611_RS08170	COG1741	Belongs to the pirin family
DM611_RS08175	COG0583	DNA-binding transcription factor activity
DM611_RS08200	COG0352	thiamine-phosphate diphosphorylase activity
DM611_RS08200	COG0351	phosphomethylpyrimidine kinase
DM611_RS08215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DM611_RS08220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DM611_RS08230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM611_RS08240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DM611_RS08245	COG0477	Major facilitator Superfamily
DM611_RS08255	COG0617	tRNA 3'-terminal CCA addition
DM611_RS08265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DM611_RS08270	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DM611_RS08280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DM611_RS08285	COG0166	Belongs to the GPI family
DM611_RS08290	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DM611_RS08300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DM611_RS08305	COG0671	phosphoesterase, PA-phosphatase related
DM611_RS08315	COG0800	Aldolase
DM611_RS08325	COG0129	dihydroxy-acid dehydratase activity
DM611_RS08335	COG0837	glucose binding
DM611_RS08360	COG2009	succinate dehydrogenase
DM611_RS08365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DM611_RS08370	COG1053	succinate dehydrogenase
DM611_RS08390	COG4591	ABC-type transport system involved in lipoprotein release permease component
DM611_RS08405	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DM611_RS08415	COG0552	protein localization to endoplasmic reticulum
DM611_RS08430	COG0742	ribosomal rna small subunit methyltransferase
DM611_RS08435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DM611_RS08445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DM611_RS08450	COG0405	Gamma-glutamyltransferase
DM611_RS08455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM611_RS08475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DM611_RS08495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DM611_RS08500	COG0415	Belongs to the DNA photolyase family
DM611_RS08505	COG2885	chlorophyll binding
DM611_RS08510	COG0583	DNA-binding transcription factor activity
DM611_RS08610	COG1404	Belongs to the peptidase S8 family
DM611_RS08815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DM611_RS08830	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM611_RS08835	COG0735	belongs to the Fur family
DM611_RS08845	COG0583	DNA-binding transcription factor activity
DM611_RS08850	COG0497	DNA recombination
DM611_RS08855	COG1420	regulation of RNA biosynthetic process
DM611_RS08860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DM611_RS08865	COG0443	Heat shock 70 kDa protein
DM611_RS08870	COG0484	heat shock protein binding
DM611_RS08875	COG2207	Transcriptional regulator
DM611_RS08880	COG2223	nitrite transmembrane transporter activity
DM611_RS08885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DM611_RS08900	COG1132	(ABC) transporter
DM611_RS08930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DM611_RS08935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DM611_RS08945	COG0343	queuine tRNA-ribosyltransferase activity
DM611_RS08950	COG1862	Preprotein translocase
DM611_RS08960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM611_RS08965	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DM611_RS08975	COG2081	HI0933 family
DM611_RS08980	COG4681	YaeQ
DM611_RS08985	COG0564	pseudouridine synthase activity
DM611_RS09000	COG0625	glutathione transferase activity
DM611_RS09005	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DM611_RS09010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DM611_RS09015	COG0513	Belongs to the DEAD box helicase family
DM611_RS09025	COG0583	DNA-binding transcription factor activity
DM611_RS09030	COG0488	(ABC) transporter
DM611_RS09055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS09070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM611_RS09075	COG2957	Belongs to the agmatine deiminase family
DM611_RS09085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DM611_RS09090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DM611_RS09100	COG0776	regulation of translation
DM611_RS09110	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DM611_RS09115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DM611_RS09125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DM611_RS09130	COG0183	Belongs to the thiolase family
DM611_RS09135	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM611_RS09135	COG1024	Enoyl-CoA hydratase
DM611_RS09145	COG0105	UTP biosynthetic process
DM611_RS09150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DM611_RS09155	COG0457	Tetratricopeptide repeat
DM611_RS09155	COG0859	PFAM glycosyl transferase family 9
DM611_RS09170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM611_RS09175	COG1160	GTP binding
DM611_RS09200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DM611_RS09205	COG0475	glutathione-regulated potassium exporter activity
DM611_RS09205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DM611_RS09225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DM611_RS09225	COG0519	Catalyzes the synthesis of GMP from XMP
DM611_RS09235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DM611_RS09240	COG0732	type I restriction modification DNA specificity domain
DM611_RS09245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DM611_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS09305	COG0640	Transcriptional regulator
DM611_RS09320	COG4716	Myosin-crossreactive antigen
DM611_RS09340	COG0431	NADPH-dependent FMN reductase
DM611_RS09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DM611_RS09355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DM611_RS09360	COG1473	amidohydrolase
DM611_RS09370	COG1126	abc transporter atp-binding protein
DM611_RS09375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM611_RS09385	COG0583	DNA-binding transcription factor activity
DM611_RS09410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DM611_RS09415	COG0583	DNA-binding transcription factor activity
DM611_RS09420	COG0477	Major facilitator Superfamily
DM611_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS09435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DM611_RS09455	COG1309	transcriptional regulator
DM611_RS09470	COG0697	spore germination
DM611_RS09475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DM611_RS09480	COG0167	dihydroorotate dehydrogenase activity
DM611_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS09500	COG1012	belongs to the aldehyde dehydrogenase family
DM611_RS09510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DM611_RS09515	COG3206	protein involved in exopolysaccharide biosynthesis
DM611_RS09515	COG0489	protein tyrosine kinase activity
DM611_RS09525	COG0438	transferase activity, transferring glycosyl groups
DM611_RS09525	COG4641	Protein conserved in bacteria
DM611_RS09545	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DM611_RS09550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DM611_RS09570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM611_RS09610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DM611_RS09625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM611_RS09655	COG0745	RESPONSE REGULATOR receiver
DM611_RS09660	COG4191	Histidine kinase
DM611_RS09660	COG0784	Response regulator, receiver
DM611_RS09665	COG4999	Histidine kinase
DM611_RS09665	COG2205	protein histidine kinase activity
DM611_RS09665	COG3850	Histidine kinase
DM611_RS09665	COG3437	response regulator, receiver
DM611_RS09670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DM611_RS09680	COG5002	protein histidine kinase activity
DM611_RS09690	COG0640	Transcriptional regulator
DM611_RS09725	COG0527	aspartate kinase activity
DM611_RS09725	COG0460	homoserine dehydrogenase
DM611_RS09730	COG0083	homoserine kinase activity
DM611_RS09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM611_RS09745	COG0124	histidyl-tRNA synthetase
DM611_RS09760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DM611_RS09765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DM611_RS09770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM611_RS09775	COG0131	Imidazoleglycerol-phosphate dehydratase
DM611_RS09775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DM611_RS09780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DM611_RS09785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DM611_RS09790	COG0107	imidazoleglycerol-phosphate synthase activity
DM611_RS09795	COG0140	phosphoribosyl-ATP diphosphatase activity
DM611_RS09795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DM611_RS09815	COG1446	asparaginase
DM611_RS09820	COG3142	Participates in the control of copper homeostasis
DM611_RS09835	COG0789	Transcriptional regulator
DM611_RS09855	COG3537	Alpha-1,2-mannosidase
DM611_RS09860	COG1609	Transcriptional regulator
DM611_RS09870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM611_RS09885	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DM611_RS09890	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DM611_RS09895	COG0235	Class ii aldolase
DM611_RS09905	COG0531	amino acid
DM611_RS09910	COG0531	amino acid
DM611_RS09920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DM611_RS09925	COG0277	FAD linked oxidase domain protein
DM611_RS09940	COG2205	protein histidine kinase activity
DM611_RS09945	COG0745	RESPONSE REGULATOR receiver
DM611_RS09950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS09955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS09970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DM611_RS10015	COG2249	NAD(P)H dehydrogenase (quinone) activity
DM611_RS10030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DM611_RS10035	COG0505	Belongs to the CarA family
DM611_RS10040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DM611_RS10045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DM611_RS10055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DM611_RS10075	COG3209	COG3209 Rhs family protein
DM611_RS10105	COG4676	Protein conserved in bacteria
DM611_RS10120	COG3279	Response regulator of the LytR AlgR family
DM611_RS10125	COG0501	Belongs to the peptidase M48B family
DM611_RS10140	COG1012	belongs to the aldehyde dehydrogenase family
DM611_RS10160	COG0784	Response regulator, receiver
DM611_RS10160	COG2198	Histidine kinase
DM611_RS10160	COG2205	protein histidine kinase activity
DM611_RS10165	COG1024	Enoyl-CoA hydratase
DM611_RS10170	COG0318	PFAM AMP-dependent synthetase and ligase
DM611_RS10175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DM611_RS10180	COG1012	belongs to the aldehyde dehydrogenase family
DM611_RS10185	COG1309	transcriptional regulator
DM611_RS10190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DM611_RS10225	COG4804	nuclease activity
DM611_RS10260	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DM611_RS10270	COG0840	transmembrane signaling receptor activity
DM611_RS10275	COG0840	transmembrane signaling receptor activity
DM611_RS10285	COG0835	chemotaxis
DM611_RS10290	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DM611_RS10295	COG0840	transmembrane signaling receptor activity
DM611_RS10305	COG0745	RESPONSE REGULATOR receiver
DM611_RS10315	COG0835	chemotaxis
DM611_RS10325	COG1360	Flagellar Motor Protein
DM611_RS10330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DM611_RS10335	COG2198	Histidine kinase
DM611_RS10335	COG0784	Response regulator, receiver
DM611_RS10335	COG0643	Histidine kinase
DM611_RS10340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DM611_RS10365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM611_RS10370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM611_RS10385	COG1987	bacterial-type flagellum assembly
DM611_RS10395	COG3190	flagellar
DM611_RS10445	COG1677	Flagellar hook-basal body complex protein FliE
DM611_RS10475	COG2197	response regulator
DM611_RS10495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DM611_RS10535	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DM611_RS10545	COG4787	bacterial-type flagellum-dependent cell motility
DM611_RS10555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DM611_RS10560	COG1558	bacterial-type flagellum-dependent cell motility
DM611_RS10565	COG1815	bacterial-type flagellum-dependent cell motility
DM611_RS10570	COG0784	Response regulator, receiver
DM611_RS10570	COG0835	chemotaxis
DM611_RS10590	COG5002	protein histidine kinase activity
DM611_RS10630	COG2915	High frequency lysogenization protein hflD homolog
DM611_RS10635	COG0482	sulfurtransferase activity
DM611_RS10650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DM611_RS10660	COG0542	response to heat
DM611_RS10695	COG0492	ferredoxin-NADP+ reductase activity
DM611_RS10700	COG1674	ftsk spoiiie
DM611_RS10715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DM611_RS10735	COG2819	hydrolase of the alpha beta superfamily
DM611_RS10745	COG4558	Periplasmic binding protein
DM611_RS10750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DM611_RS10755	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DM611_RS10770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DM611_RS10785	COG2205	protein histidine kinase activity
DM611_RS10785	COG2198	Histidine kinase
DM611_RS10785	COG0784	Response regulator, receiver
DM611_RS10800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DM611_RS10810	COG0577	efflux transmembrane transporter activity
DM611_RS10810	COG1136	(ABC) transporter
DM611_RS10835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DM611_RS10850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DM611_RS10860	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DM611_RS10875	COG1595	DNA-templated transcription, initiation
DM611_RS10895	COG0784	Response regulator, receiver
DM611_RS10900	COG4251	negative regulation of phosphorylation
DM611_RS10910	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DM611_RS10920	COG1073	alpha beta
DM611_RS10925	COG0300	oxidoreductase activity
DM611_RS10945	COG1073	alpha beta
DM611_RS10950	COG1064	alcohol dehydrogenase
DM611_RS10955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS10970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DM611_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS11000	COG1566	PFAM secretion protein HlyD family protein
DM611_RS11010	COG1252	NADH dehydrogenase
DM611_RS11020	COG0456	acetyltransferase
DM611_RS11020	COG0454	-acetyltransferase
DM611_RS11030	COG2259	Doxx family
DM611_RS11035	COG0583	DNA-binding transcription factor activity
DM611_RS11040	COG1741	Belongs to the pirin family
DM611_RS11220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DM611_RS11290	COG0431	NADPH-dependent FMN reductase
DM611_RS11315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM611_RS11320	COG0573	inorganic phosphate transmembrane transporter activity
DM611_RS11335	COG0704	Plays a role in the regulation of phosphate uptake
DM611_RS11375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS11410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM611_RS11505	COG0010	Belongs to the arginase family
DM611_RS11560	COG2132	Multicopper oxidase
DM611_RS11640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DM611_RS11730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DM611_RS11735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DM611_RS11740	COG2080	2 iron, 2 sulfur cluster binding
DM611_RS11745	COG1764	response to oxidative stress
DM611_RS11755	COG0583	DNA-binding transcription factor activity
DM611_RS11775	COG1595	DNA-templated transcription, initiation
DM611_RS11780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM611_RS11790	COG1309	transcriptional regulator
DM611_RS11825	COG0583	DNA-binding transcription factor activity
DM611_RS11840	COG1609	Transcriptional regulator
DM611_RS11845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM611_RS11845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM611_RS11850	COG1105	Belongs to the carbohydrate kinase PfkB family
DM611_RS11855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DM611_RS11855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DM611_RS11880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DM611_RS11885	COG0583	DNA-binding transcription factor activity
DM611_RS11900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DM611_RS11925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DM611_RS11930	COG5265	(ABC) transporter
DM611_RS11950	COG4555	ABC transporter
DM611_RS11975	COG2207	Transcriptional regulator
DM611_RS11985	COG0789	Transcriptional regulator
DM611_RS12020	COG0596	Alpha beta hydrolase
DM611_RS12030	COG0642	Histidine kinase
DM611_RS12040	COG0318	PFAM AMP-dependent synthetase and ligase
DM611_RS12070	COG1404	Belongs to the peptidase S8 family
DM611_RS12090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM611_RS12100	COG0346	lactoylglutathione lyase activity
DM611_RS12110	COG2204	response regulator
DM611_RS12195	COG0577	efflux transmembrane transporter activity
DM611_RS12195	COG1136	(ABC) transporter
DM611_RS12210	COG0745	RESPONSE REGULATOR receiver
DM611_RS12215	COG2205	protein histidine kinase activity
DM611_RS12235	COG4774	siderophore transport
DM611_RS12255	COG3214	Protein conserved in bacteria
DM611_RS12265	COG4774	siderophore transport
DM611_RS12320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DM611_RS12325	COG1285	pathogenesis
DM611_RS12330	COG4191	Histidine kinase
DM611_RS12335	COG4566	intracellular signal transduction
DM611_RS12390	COG0243	molybdopterin cofactor binding
DM611_RS12415	COG0477	Major facilitator Superfamily
DM611_RS12440	COG1136	(ABC) transporter
DM611_RS12455	COG4771	TonB-dependent receptor
DM611_RS12475	COG0745	RESPONSE REGULATOR receiver
DM611_RS12485	COG0583	DNA-binding transcription factor activity
DM611_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS12520	COG0642	Histidine kinase
DM611_RS12525	COG3537	Alpha-1,2-mannosidase
DM611_RS12545	COG0477	Major facilitator Superfamily
DM611_RS12560	COG2202	Pas domain
DM611_RS12560	COG3920	Histidine kinase
DM611_RS12605	COG1335	isochorismatase
DM611_RS12610	COG1335	isochorismatase
DM611_RS12620	COG0488	(ABC) transporter
DM611_RS12645	COG0811	peptide transport
DM611_RS12770	COG0840	transmembrane signaling receptor activity
DM611_RS12775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DM611_RS12795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DM611_RS12800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DM611_RS12805	COG1120	ATPase activity
DM611_RS12815	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DM611_RS12820	COG4149	molybdate abc transporter
DM611_RS12825	COG0725	ABC transporter, periplasmic molybdate-binding protein
DM611_RS12830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM611_RS12845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM611_RS12850	COG2181	nitrate reductase activity
DM611_RS12855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DM611_RS12860	COG1140	nitrate reductase beta subunit
DM611_RS12865	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DM611_RS12870	COG2223	nitrite transmembrane transporter activity
DM611_RS12880	COG0746	molybdenum cofactor guanylyltransferase activity
DM611_RS12885	COG0314	molybdopterin synthase activity
DM611_RS12895	COG0303	'Molybdopterin
DM611_RS12900	COG0315	cyclic pyranopterin monophosphate synthase activity
DM611_RS12900	COG0521	Mo-molybdopterin cofactor biosynthetic process
DM611_RS12905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DM611_RS12930	COG0789	Transcriptional regulator
DM611_RS12935	COG0431	NADPH-dependent FMN reductase
DM611_RS12945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DM611_RS12950	COG0798	PFAM Bile acid sodium symporter
DM611_RS13010	COG1943	Transposase
DM611_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS13020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM611_RS13020	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DM611_RS13025	COG3433	isochorismatase activity
DM611_RS13025	COG1535	isochorismatase
DM611_RS13030	COG3433	isochorismatase activity
DM611_RS13030	COG1535	isochorismatase
DM611_RS13035	COG1021	2,3-dihydroxybenzoate-AMP ligase
DM611_RS13040	COG1169	isochorismate synthase
DM611_RS13050	COG2409	Drug exporters of the RND superfamily
DM611_RS13055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DM611_RS13120	COG1914	H( )-stimulated, divalent metal cation uptake system
DM611_RS13135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DM611_RS13140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DM611_RS13150	COG4206	TonB-dependent receptor
DM611_RS13155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DM611_RS13200	COG4772	TonB-dependent receptor
DM611_RS13220	COG2226	methyltransferase
DM611_RS13265	COG4964	Belongs to the GSP D family
DM611_RS13320	COG2814	Major facilitator Superfamily
DM611_RS13330	COG1228	amidohydrolase
DM611_RS13340	COG1335	isochorismatase
DM611_RS13355	COG3850	Histidine kinase
DM611_RS13360	COG2197	response regulator
DM611_RS13365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DM611_RS13375	COG0583	DNA-binding transcription factor activity
DM611_RS13390	COG3161	chorismate lyase activity
DM611_RS13480	COG2885	chlorophyll binding
DM611_RS13700	COG0277	FAD linked oxidase domain protein
DM611_RS13705	COG1304	FMN binding
DM611_RS13710	COG2186	Transcriptional regulator
DM611_RS13745	COG0477	Major facilitator Superfamily
DM611_RS13805	COG0587	DNA-directed DNA polymerase activity
DM611_RS13820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DM611_RS13825	COG0519	Catalyzes the synthesis of GMP from XMP
DM611_RS13825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DM611_RS13845	COG1595	DNA-templated transcription, initiation
DM611_RS13855	COG4206	TonB-dependent receptor
DM611_RS13855	COG1629	transport
DM611_RS13880	COG0531	amino acid
DM611_RS13895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM611_RS13905	COG0789	Transcriptional regulator
DM611_RS13995	COG5002	protein histidine kinase activity
DM611_RS13995	COG3447	MASE1 domain protein
DM611_RS13995	COG5001	Diguanylate cyclase
DM611_RS14000	COG2183	response to ionizing radiation
DM611_RS14025	COG3243	poly(R)-hydroxyalkanoic acid synthase
DM611_RS14040	COG1073	alpha beta
DM611_RS14040	COG2226	methyltransferase
DM611_RS14045	COG0534	Mate efflux family protein
DM611_RS14065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DM611_RS14075	COG0668	transmembrane transport
DM611_RS14080	COG1902	pentaerythritol trinitrate reductase activity
DM611_RS14090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DM611_RS14095	COG0590	tRNA wobble adenosine to inosine editing
DM611_RS14100	COG1733	regulation of RNA biosynthetic process
DM611_RS14110	COG0456	acetyltransferase
DM611_RS14135	COG2814	Major facilitator Superfamily
DM611_RS14165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS14185	COG0745	RESPONSE REGULATOR receiver
DM611_RS14205	COG1136	(ABC) transporter
DM611_RS14205	COG0577	efflux transmembrane transporter activity
DM611_RS14230	COG0210	DNA helicase
DM611_RS14285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM611_RS14290	COG1061	Type III restriction enzyme res subunit
DM611_RS14295	COG1002	Type II restriction enzyme, methylase subunits
DM611_RS14345	COG0583	DNA-binding transcription factor activity
DM611_RS14350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DM611_RS14360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DM611_RS14375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM611_RS14380	COG0077	Prephenate dehydratase
DM611_RS14380	COG1605	Chorismate mutase
DM611_RS14385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DM611_RS14430	COG1228	amidohydrolase
DM611_RS14445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DM611_RS14500	COG2957	Belongs to the agmatine deiminase family
DM611_RS14505	COG0583	DNA-binding transcription factor activity
DM611_RS14565	COG4993	Dehydrogenase
DM611_RS14575	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DM611_RS14595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DM611_RS14600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM611_RS14620	COG0359	binds to the 23S rRNA
DM611_RS14625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DM611_RS14630	COG0360	Binds together with S18 to 16S ribosomal RNA
DM611_RS14640	COG0316	Belongs to the HesB IscA family
DM611_RS14645	COG0017	Asparaginyl-tRNA synthetase
DM611_RS14665	COG0288	reversible hydration of carbon dioxide
DM611_RS14675	COG3844	kynureninase activity
DM611_RS14680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS14685	COG2925	Exonuclease
DM611_RS14695	COG0667	Aldo Keto reductase
DM611_RS14715	COG2902	Dehydrogenase
DM611_RS14725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS14730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS14735	COG1960	acyl-CoA dehydrogenase activity
DM611_RS14750	COG0646	methionine synthase
DM611_RS14750	COG1410	methionine synthase
DM611_RS14760	COG2755	lipolytic protein G-D-S-L family
DM611_RS14760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DM611_RS14770	COG2900	Belongs to the SlyX family
DM611_RS14785	COG0386	Belongs to the glutathione peroxidase family
DM611_RS14795	COG1725	Transcriptional regulator
DM611_RS14800	COG1131	(ABC) transporter
DM611_RS14825	COG0114	fumarate hydratase activity
DM611_RS14835	COG2850	peptidyl-arginine hydroxylation
DM611_RS14845	COG0567	Dehydrogenase, E1 component
DM611_RS14860	COG0583	DNA-binding transcription factor activity
DM611_RS14880	COG3540	Alkaline phosphatase
DM611_RS14890	COG0305	Participates in initiation and elongation during chromosome replication
DM611_RS14910	COG0625	glutathione transferase activity
DM611_RS14930	COG0084	hydrolase, TatD family'
DM611_RS14935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DM611_RS14965	COG1393	Belongs to the ArsC family
DM611_RS14970	COG0625	glutathione transferase activity
DM611_RS14985	COG1595	DNA-templated transcription, initiation
DM611_RS14990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM611_RS15010	COG0386	Belongs to the glutathione peroxidase family
DM611_RS15015	COG0339	signal peptide processing
DM611_RS15020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DM611_RS15040	COG0705	Rhomboid family
DM611_RS15045	COG3104	oligopeptide transport
DM611_RS15055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DM611_RS15060	COG4290	ribonuclease
DM611_RS15075	COG0316	Belongs to the HesB IscA family
DM611_RS15075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DM611_RS15080	COG2154	pterin-4-alpha-carbinolamine dehydratase
DM611_RS15090	COG0428	transporter
DM611_RS15100	COG1530	ribonuclease E activity
DM611_RS15115	COG0395	ABC-type sugar transport system, permease component
DM611_RS15145	COG0271	Belongs to the BolA IbaG family
DM611_RS15150	COG2350	Protein conserved in bacteria
DM611_RS15155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DM611_RS15160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DM611_RS15165	COG1187	pseudouridine synthase activity
DM611_RS15175	COG2814	Major facilitator Superfamily
DM611_RS15200	COG0436	Aminotransferase
DM611_RS15205	COG4133	protoheme IX ABC transporter activity
DM611_RS15225	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DM611_RS15240	COG3088	subunit of a heme lyase
DM611_RS15240	COG4235	cytochrome complex assembly
DM611_RS15250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DM611_RS15260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DM611_RS15265	COG4988	ABC transporter
DM611_RS15275	COG1294	oxidase, subunit
DM611_RS15330	COG0726	polysaccharide deacetylase
DM611_RS15330	COG1649	PFAM Uncharacterised BCR, COG1649
DM611_RS15335	COG1215	transferase activity, transferring glycosyl groups
DM611_RS15345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DM611_RS15360	COG0165	Argininosuccinate lyase
DM611_RS15365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DM611_RS15375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DM611_RS15380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DM611_RS15385	COG0137	argininosuccinate synthase activity
DM611_RS15390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DM611_RS15405	COG2166	iron-sulfur cluster assembly
DM611_RS15425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DM611_RS15450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DM611_RS15455	COG0402	S-adenosylhomocysteine deaminase activity
DM611_RS15460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DM611_RS15465	COG1509	lysine 2,3-aminomutase activity
DM611_RS15470	COG3300	MHYT domain
DM611_RS15470	COG5001	Diguanylate cyclase
DM611_RS15490	COG0501	Belongs to the peptidase M48B family
DM611_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS15520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DM611_RS15525	COG0860	N-Acetylmuramoyl-L-alanine amidase
DM611_RS15530	COG0802	atpase or kinase
DM611_RS15535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DM611_RS15535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DM611_RS15540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DM611_RS15545	COG1570	exodeoxyribonuclease VII activity
DM611_RS15555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DM611_RS15570	COG4771	TonB-dependent receptor
DM611_RS15575	COG1309	transcriptional regulator
DM611_RS15605	COG4735	regulation of single-species biofilm formation
DM611_RS15620	COG3081	Nucleoid-associated protein
DM611_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS15645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DM611_RS15645	COG2169	Transcriptional regulator
DM611_RS15650	COG2130	NADP-dependent
DM611_RS15675	COG1960	acyl-CoA dehydrogenase activity
DM611_RS15690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DM611_RS15725	COG2076	Multidrug Resistance protein
DM611_RS15730	COG5487	UPF0391 membrane protein
DM611_RS15735	COG1280	lysine exporter protein (LysE YggA)
DM611_RS15740	COG0740	serine-type endopeptidase activity
DM611_RS15755	COG1794	racemase activity, acting on amino acids and derivatives
DM611_RS15795	COG0776	regulation of translation
DM611_RS15800	COG0072	phenylalanine-tRNA ligase activity
DM611_RS15800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DM611_RS15805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DM611_RS15810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DM611_RS15815	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DM611_RS15820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DM611_RS15825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DM611_RS15860	COG1185	polyribonucleotide nucleotidyltransferase activity
DM611_RS15865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DM611_RS15875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DM611_RS15880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DM611_RS15885	COG0195	Participates in both transcription termination and antitermination
DM611_RS15890	COG0779	Required for maturation of 30S ribosomal subunits
DM611_RS15905	COG1007	ATP synthesis coupled electron transport
DM611_RS15920	COG0713	ATP synthesis coupled electron transport
DM611_RS15930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DM611_RS15935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DM611_RS15950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DM611_RS15955	COG0649	NAD binding
DM611_RS15960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DM611_RS15965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DM611_RS15970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DM611_RS15985	COG0149	triose-phosphate isomerase activity
DM611_RS15995	COG3083	sulfuric ester hydrolase activity
DM611_RS16000	COG0438	transferase activity, transferring glycosyl groups
DM611_RS16005	COG0726	polysaccharide deacetylase
DM611_RS16010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DM611_RS16020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DM611_RS16025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DM611_RS16030	COG0159	tryptophan synthase activity
DM611_RS16040	COG0133	tryptophan synthase activity
DM611_RS16075	COG0135	phosphoribosylanthranilate isomerase activity
DM611_RS16080	COG0101	tRNA pseudouridine synthase activity
DM611_RS16095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DM611_RS16105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DM611_RS16110	COG2890	protein-(glutamine-N5) methyltransferase activity
DM611_RS16115	COG1999	signal sequence binding
DM611_RS16120	COG0688	phosphatidylethanolamine metabolic process
DM611_RS16135	COG0433	COG0433 Predicted ATPase
DM611_RS16140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DM611_RS16150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DM611_RS16155	COG0412	Dienelactone hydrolase
DM611_RS16165	COG0717	Belongs to the dCTP deaminase family
DM611_RS16170	COG0489	protein tyrosine kinase activity
DM611_RS16175	COG4771	TonB-dependent receptor
DM611_RS16190	COG4771	TonB-dependent receptor
DM611_RS16195	COG3590	peptidase
DM611_RS16235	COG0697	spore germination
DM611_RS16245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM611_RS16250	COG2311	Membrane
DM611_RS16255	COG1047	Peptidyl-prolyl cis-trans
DM611_RS16260	COG0791	NLP P60 protein
DM611_RS16265	COG0791	NLP P60 protein
DM611_RS16270	COG1301	dicarboxylic acid transport
DM611_RS16290	COG1722	exodeoxyribonuclease VII activity
DM611_RS16295	COG0142	geranyltranstransferase activity
DM611_RS16305	COG0312	modulator of DNA gyrase
DM611_RS16310	COG3028	Belongs to the UPF0307 family
DM611_RS16315	COG0312	modulator of DNA gyrase
DM611_RS16335	COG2968	Membrane
DM611_RS16345	COG4771	TonB-dependent receptor
DM611_RS16360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DM611_RS16370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DM611_RS16385	COG0495	leucyl-tRNA aminoacylation
DM611_RS16395	COG3118	belongs to the thioredoxin family
DM611_RS16405	COG5001	Diguanylate cyclase
DM611_RS16405	COG3706	GGDEF domain
DM611_RS16405	COG4251	negative regulation of phosphorylation
DM611_RS16405	COG2203	Gaf domain
DM611_RS16425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DM611_RS16435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DM611_RS16440	COG0346	lactoylglutathione lyase activity
DM611_RS16450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DM611_RS16450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DM611_RS16460	COG2878	Part of a membrane complex involved in electron transport
DM611_RS16465	COG0251	oxidation-reduction process
DM611_RS16500	COG2824	Alkylphosphonate utilization operon protein PhnA
DM611_RS16505	COG0443	Heat shock 70 kDa protein
DM611_RS16545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DM611_RS16550	COG3122	Protein conserved in bacteria
DM611_RS16555	COG1451	nucleotide metabolic process
DM611_RS16565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DM611_RS16585	COG0183	Belongs to the thiolase family
DM611_RS16600	COG1960	acyl-CoA dehydrogenase activity
DM611_RS16610	COG1793	dna ligase
DM611_RS16615	COG1201	RNA secondary structure unwinding
DM611_RS16630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM611_RS16635	COG1278	Cold shock
DM611_RS16640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DM611_RS16645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DM611_RS16650	COG1472	Belongs to the glycosyl hydrolase 3 family
DM611_RS16655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DM611_RS16660	COG2954	triphosphatase activity
DM611_RS16665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DM611_RS16670	COG0745	RESPONSE REGULATOR receiver
DM611_RS16675	COG1381	Involved in DNA repair and RecF pathway recombination
DM611_RS16680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DM611_RS16695	COG0681	Belongs to the peptidase S26 family
DM611_RS16700	COG0481	GTPase activity
DM611_RS16705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM611_RS16725	COG1741	Belongs to the pirin family
DM611_RS16730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DM611_RS16740	COG1741	Belongs to the pirin family
DM611_RS16750	COG1966	Carbon starvation protein
DM611_RS16755	COG2879	small protein
DM611_RS16770	COG2205	protein histidine kinase activity
DM611_RS16810	COG2814	Major facilitator Superfamily
DM611_RS16815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DM611_RS16815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DM611_RS16825	COG1113	amino acid transport
DM611_RS16830	COG2207	Transcriptional regulator
DM611_RS16830	COG1917	Cupin 2, conserved barrel domain protein
DM611_RS16845	COG0840	transmembrane signaling receptor activity
DM611_RS16855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DM611_RS16865	COG0330	HflC and HflK could
DM611_RS16870	COG0330	HflC and HflK could
DM611_RS16875	COG0604	alcohol dehydrogenase
DM611_RS16890	COG0678	peroxiredoxin activity
DM611_RS16900	COG4953	penicillin-binding protein 1C
DM611_RS16905	COG2373	Large extracellular alpha-helical protein
DM611_RS16910	COG2079	MmgE PrpD family protein
DM611_RS16915	COG2828	Protein conserved in bacteria
DM611_RS16925	COG3609	addiction module antidote protein, CC2985 family
DM611_RS16945	COG3829	transcription factor binding
DM611_RS16960	COG0259	pyridoxamine-phosphate oxidase activity
DM611_RS16975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DM611_RS16995	COG0477	Major facilitator Superfamily
DM611_RS17015	COG3038	cytochrome b561
DM611_RS17030	COG1760	l-serine dehydratase
DM611_RS17035	COG2267	carboxylic ester hydrolase activity
DM611_RS17040	COG0527	aspartate kinase activity
DM611_RS17040	COG0460	homoserine dehydrogenase
DM611_RS17045	COG0626	cystathionine gamma-synthase activity
DM611_RS17050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DM611_RS17055	COG0739	heme binding
DM611_RS17060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DM611_RS17065	COG1272	protein, Hemolysin III
DM611_RS17080	COG0463	Glycosyl transferase, family 2
DM611_RS17085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DM611_RS17090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DM611_RS17100	COG4771	TonB-dependent receptor
DM611_RS17105	COG2226	methyltransferase
DM611_RS17135	COG1309	transcriptional regulator
DM611_RS17175	COG0583	DNA-binding transcription factor activity
DM611_RS17185	COG0509	glycine decarboxylation via glycine cleavage system
DM611_RS17190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DM611_RS17200	COG0330	HflC and HflK could
DM611_RS17210	COG1742	UPF0060 membrane protein
DM611_RS17215	COG3956	TIGRFAM MazG family protein
DM611_RS17220	COG1218	3'(2'),5'-bisphosphate nucleotidase
DM611_RS17225	COG0494	nUDIX hydrolase
DM611_RS17235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DM611_RS17250	COG2198	Histidine kinase
DM611_RS17250	COG0643	Histidine kinase
DM611_RS17250	COG0784	Response regulator, receiver
DM611_RS17255	COG0840	transmembrane signaling receptor activity
DM611_RS17260	COG0835	chemotaxis
DM611_RS17275	COG0189	ligase activity
DM611_RS17290	COG1199	ATP-dependent helicase activity
DM611_RS17300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DM611_RS17315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM611_RS17325	COG1643	Atp-dependent helicase
DM611_RS17330	COG0783	Belongs to the Dps family
DM611_RS17335	COG0514	ATP-dependent DNA helicase (RecQ)
DM611_RS17345	COG2132	Multicopper oxidase
DM611_RS17400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DM611_RS17405	COG0602	queuosine metabolic process
DM611_RS17415	COG2885	chlorophyll binding
DM611_RS17420	COG0823	Involved in the tonB-independent uptake of proteins
DM611_RS17435	COG0811	peptide transport
DM611_RS17440	COG0824	Thioesterase
DM611_RS17445	COG2255	four-way junction helicase activity
DM611_RS17455	COG0632	four-way junction helicase activity
DM611_RS17460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DM611_RS17465	COG0217	transcriptional regulatory protein
DM611_RS17480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DM611_RS17510	COG0488	(ABC) transporter
DM611_RS17520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DM611_RS17520	COG4651	solute:proton antiporter activity
DM611_RS17530	COG0745	RESPONSE REGULATOR receiver
DM611_RS17535	COG2205	protein histidine kinase activity
DM611_RS17545	COG0542	response to heat
DM611_RS17570	COG0028	Belongs to the TPP enzyme family
DM611_RS17595	COG3387	PFAM Glycoside hydrolase 15-related
DM611_RS17600	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DM611_RS17605	COG3011	Protein conserved in bacteria
DM611_RS17620	COG0564	pseudouridine synthase activity
DM611_RS17625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM611_RS17635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM611_RS17635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DM611_RS17660	COG1132	(ABC) transporter
DM611_RS17670	COG0045	succinate-CoA ligase (ADP-forming) activity
DM611_RS17690	COG4969	Belongs to the N-Me-Phe pilin family
DM611_RS17700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DM611_RS17750	COG2205	protein histidine kinase activity
DM611_RS17755	COG0745	RESPONSE REGULATOR receiver
DM611_RS17765	COG0189	ligase activity
DM611_RS17790	COG3240	lipase activity
DM611_RS17790	COG4625	pathogenesis
DM611_RS17800	COG2022	thiamine diphosphate biosynthetic process
DM611_RS17805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DM611_RS17810	COG3273	potassium ion transport
DM611_RS17810	COG0471	metal ion transport
DM611_RS17830	COG1970	mechanosensitive ion channel activity
DM611_RS17840	COG1115	amino acid carrier protein
DM611_RS17850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM611_RS17855	COG1115	amino acid carrier protein
DM611_RS17860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DM611_RS17865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS17870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS17900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DM611_RS17910	COG3588	fructose-bisphosphate aldolase
DM611_RS17915	COG0469	pyruvate kinase activity
DM611_RS17925	COG0126	phosphoglycerate kinase activity
DM611_RS17940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DM611_RS17945	COG3047	cAMP biosynthetic process
DM611_RS17995	COG3093	addiction module antidote protein HigA
DM611_RS18005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DM611_RS18010	COG1301	dicarboxylic acid transport
DM611_RS18040	COG0714	Associated with various cellular activities
DM611_RS18070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DM611_RS18125	COG0254	rRNA binding
DM611_RS18135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DM611_RS18145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM611_RS18150	COG1758	RNA polymerase activity
DM611_RS18160	COG3383	formate dehydrogenase (NAD+) activity
DM611_RS18160	COG0243	molybdopterin cofactor binding
DM611_RS18165	COG0243	molybdopterin cofactor binding
DM611_RS18165	COG3383	formate dehydrogenase (NAD+) activity
DM611_RS18170	COG0437	4 iron, 4 sulfur cluster binding
DM611_RS18175	COG2864	formate dehydrogenase
DM611_RS18185	COG1921	L-seryl-tRNASec selenium transferase activity
DM611_RS18190	COG3276	selenocysteine insertion sequence binding
DM611_RS18200	COG0709	Synthesizes selenophosphate from selenide and ATP
DM611_RS18240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DM611_RS18245	COG0582	viral genome integration into host DNA
DM611_RS18250	COG1561	YicC-like family, N-terminal region
DM611_RS18255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DM611_RS18260	COG0346	lactoylglutathione lyase activity
DM611_RS18270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM611_RS18285	COG0006	proline dipeptidase activity
DM611_RS18290	COG0006	proline dipeptidase activity
DM611_RS18295	COG3079	Belongs to the UPF0149 family
DM611_RS18315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DM611_RS18325	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DM611_RS18335	COG2912	Transglutaminase-like superfamily
DM611_RS18340	COG1773	rubredoxin
DM611_RS18350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DM611_RS18365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DM611_RS18370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM611_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS18400	COG0671	phosphoesterase, PA-phosphatase related
DM611_RS18410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DM611_RS18415	COG0563	adenylate kinase activity
DM611_RS18435	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DM611_RS18445	COG0848	biopolymer transport protein
DM611_RS18455	COG2832	Protein of unknown function (DUF454)
DM611_RS18490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DM611_RS18515	COG0745	RESPONSE REGULATOR receiver
DM611_RS18525	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DM611_RS18530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DM611_RS18540	COG0405	Gamma-glutamyltransferase
DM611_RS18545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DM611_RS18565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DM611_RS18570	COG2226	methyltransferase
DM611_RS18585	COG0473	3-isopropylmalate dehydrogenase activity
DM611_RS18600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS18605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS18615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DM611_RS18620	COG1538	Outer membrane efflux protein
DM611_RS18625	COG0531	amino acid
DM611_RS18630	COG1519	Transferase
DM611_RS18635	COG1560	Kdo2-lipid A biosynthetic process
DM611_RS18665	COG1301	dicarboxylic acid transport
DM611_RS18675	COG4191	Histidine kinase
DM611_RS18695	COG0642	Histidine kinase
DM611_RS18710	COG2851	Citrate transporter
DM611_RS18715	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS18740	COG1162	GTPase activity
DM611_RS18745	COG0436	Aminotransferase
DM611_RS18765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DM611_RS18780	COG1228	amidohydrolase
DM611_RS18785	COG0804	urea catabolic process
DM611_RS18795	COG1307	EDD domain protein, DegV family
DM611_RS18835	COG3706	GGDEF domain
DM611_RS18835	COG4251	negative regulation of phosphorylation
DM611_RS18835	COG5001	Diguanylate cyclase
DM611_RS18835	COG2203	Gaf domain
DM611_RS18840	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DM611_RS18850	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DM611_RS18860	COG4206	TonB-dependent receptor
DM611_RS18870	COG1902	pentaerythritol trinitrate reductase activity
DM611_RS18905	COG0583	DNA-binding transcription factor activity
DM611_RS18910	COG1064	alcohol dehydrogenase
DM611_RS18920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DM611_RS18945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DM611_RS18950	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DM611_RS18960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DM611_RS18965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DM611_RS18980	COG1522	sequence-specific DNA binding
DM611_RS18990	COG4773	Receptor
DM611_RS19025	COG0617	tRNA 3'-terminal CCA addition
DM611_RS19050	COG3468	outer membrane autotransporter barrel domain protein
DM611_RS19060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DM611_RS19065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM611_RS19070	COG1609	Transcriptional regulator
DM611_RS19080	COG0837	glucose binding
DM611_RS19090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DM611_RS19110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DM611_RS19120	COG4191	Histidine kinase
DM611_RS19125	COG0784	Response regulator, receiver
DM611_RS19130	COG4251	negative regulation of phosphorylation
DM611_RS19135	COG2823	Periplasmic or secreted lipoprotein
DM611_RS19140	COG0673	inositol 2-dehydrogenase activity
DM611_RS19145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DM611_RS19165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DM611_RS19170	COG0321	lipoyl(octanoyl) transferase activity
DM611_RS19175	COG2921	Belongs to the UPF0250 family
DM611_RS19185	COG1686	Belongs to the peptidase S11 family
DM611_RS19190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DM611_RS19195	COG2951	lytic endotransglycosylase activity
DM611_RS19200	COG0772	Belongs to the SEDS family
DM611_RS19205	COG0772	Belongs to the SEDS family
DM611_RS19220	COG1792	Involved in formation and maintenance of cell shape
DM611_RS19225	COG1077	Cell shape determining protein MreB Mrl
DM611_RS19230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM611_RS19245	COG0308	aminopeptidase N
DM611_RS19250	COG2226	methyltransferase
DM611_RS19280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS19300	COG0673	inositol 2-dehydrogenase activity
DM611_RS19310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DM611_RS19330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DM611_RS19340	COG2832	Protein of unknown function (DUF454)
DM611_RS19350	COG0436	Aminotransferase
DM611_RS19355	COG1505	serine-type exopeptidase activity
DM611_RS19380	COG0697	spore germination
DM611_RS19385	COG1666	GTP binding
DM611_RS19415	COG0339	signal peptide processing
DM611_RS19425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DM611_RS19445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM611_RS19455	COG1136	(ABC) transporter
DM611_RS19480	COG4191	Histidine kinase
DM611_RS19490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DM611_RS19505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DM611_RS19510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DM611_RS19515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DM611_RS19520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DM611_RS19525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DM611_RS19530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DM611_RS19540	COG0356	it plays a direct role in the translocation of protons across the membrane
DM611_RS19555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM611_RS19560	COG0508	dehydrogenase complex catalyzes the overall conversion of
DM611_RS19580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DM611_RS19605	COG0181	hydroxymethylbilane synthase activity
DM611_RS19615	COG0745	RESPONSE REGULATOR receiver
DM611_RS19615	COG2972	Histidine kinase
DM611_RS19635	COG4771	TonB-dependent receptor
DM611_RS19645	COG0840	transmembrane signaling receptor activity
DM611_RS19675	COG0477	Major facilitator Superfamily
DM611_RS19705	COG0583	DNA-binding transcription factor activity
DM611_RS19710	COG0477	Major facilitator Superfamily
DM611_RS19745	COG0625	glutathione transferase activity
DM611_RS19760	COG2259	Doxx family
DM611_RS19765	COG4977	sequence-specific DNA binding
DM611_RS19825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM611_RS19830	COG1490	D-aminoacyl-tRNA deacylase activity
DM611_RS19875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM611_RS19875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM611_RS19880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DM611_RS19885	COG0242	peptide deformylase activity
DM611_RS19895	COG0758	DNA mediated transformation
DM611_RS19900	COG2922	Belongs to the Smg family
DM611_RS19910	COG1714	RDD family
DM611_RS19915	COG1754	DNA topoisomerase type I activity
DM611_RS19915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DM611_RS19920	COG0009	L-threonylcarbamoyladenylate synthase
DM611_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS19945	COG0616	signal peptide processing
DM611_RS19950	COG0534	Mate efflux family protein
DM611_RS19965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DM611_RS19970	COG0625	glutathione transferase activity
DM611_RS19980	COG1252	NADH dehydrogenase
DM611_RS20000	COG2860	membrane
DM611_RS20005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DM611_RS20030	COG1846	Transcriptional regulator
DM611_RS20055	COG0625	glutathione transferase activity
DM611_RS20065	COG0459	protein refolding
DM611_RS20070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DM611_RS20075	COG2356	endonuclease I
DM611_RS20080	COG1324	tolerance protein
DM611_RS20090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM611_RS20100	COG0840	transmembrane signaling receptor activity
DM611_RS20120	COG4585	Histidine kinase
DM611_RS20140	COG0583	DNA-binding transcription factor activity
DM611_RS20150	COG1785	Belongs to the alkaline phosphatase family
DM611_RS20155	COG1686	Belongs to the peptidase S11 family
DM611_RS20165	COG2249	NAD(P)H dehydrogenase (quinone) activity
DM611_RS20175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DM611_RS20185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DM611_RS20190	COG0511	ligase activity, forming carbon-carbon bonds
DM611_RS20195	COG0439	Biotin carboxylase
DM611_RS20210	COG2264	protein methyltransferase activity
DM611_RS20220	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DM611_RS20225	COG4589	Belongs to the CDS family
DM611_RS20230	COG0204	Acyl-transferase
DM611_RS20240	COG2453	phosphatase
DM611_RS20240	COG0671	phosphoesterase, PA-phosphatase related
DM611_RS20245	COG2267	carboxylic ester hydrolase activity
DM611_RS20250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DM611_RS20260	COG0138	bifunctional purine biosynthesis protein purh
DM611_RS20270	COG0151	Belongs to the GarS family
DM611_RS20285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM611_RS20290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DM611_RS20295	COG2201	protein-glutamate methylesterase activity
DM611_RS20300	COG2177	Part of the ABC transporter FtsEX involved in
DM611_RS20305	COG2884	Cell division ATP-binding protein ftsE
DM611_RS20310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DM611_RS20325	COG3118	belongs to the thioredoxin family
DM611_RS20330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DM611_RS20335	COG3706	GGDEF domain
DM611_RS20345	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DM611_RS20380	COG1652	LysM domain
DM611_RS20385	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DM611_RS20385	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DM611_RS20405	COG1473	amidohydrolase
DM611_RS20410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS20415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS20420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS20425	COG1289	transmembrane transporter activity
DM611_RS20430	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS20435	COG2814	Major facilitator Superfamily
DM611_RS20465	COG0316	Belongs to the HesB IscA family
DM611_RS20505	COG1051	belongs to the nudix hydrolase family
DM611_RS20520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DM611_RS20525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DM611_RS20530	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DM611_RS20540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DM611_RS20545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM611_RS20550	COG0730	response to heat
DM611_RS20560	COG0134	indole-3-glycerol-phosphate synthase activity
DM611_RS20565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DM611_RS20585	COG1597	lipid kinase activity
DM611_RS20600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DM611_RS20605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DM611_RS20615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DM611_RS20615	COG2111	Na H antiporter
DM611_RS20620	COG1006	Multisubunit Na H antiporter MnhC subunit
DM611_RS20625	COG0651	ATP synthesis coupled electron transport
DM611_RS20630	COG1863	multisubunit Na H antiporter MnhE subunit
DM611_RS20635	COG2212	antiporter activity
DM611_RS20640	COG1320	monovalent cation:proton antiporter activity
DM611_RS20645	COG0530	calcium, potassium:sodium antiporter activity
DM611_RS20660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DM611_RS20675	COG4804	nuclease activity
DM611_RS20690	COG3104	oligopeptide transport
DM611_RS20695	COG3483	tryptophan 2,3-dioxygenase activity
DM611_RS20730	COG2378	regulation of single-species biofilm formation
DM611_RS20745	COG2354	Protein conserved in bacteria
DM611_RS20750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DM611_RS20755	COG1368	sulfuric ester hydrolase activity
DM611_RS20760	COG3264	Mechanosensitive ion channel
DM611_RS20760	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DM611_RS20775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DM611_RS20810	COG1166	arginine decarboxylase activity
DM611_RS20815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DM611_RS20835	COG2960	long-chain fatty acid transporting porin activity
DM611_RS20885	COG3209	COG3209 Rhs family protein
DM611_RS20890	COG0606	chelatase, subunit chli
DM611_RS20905	COG0561	phosphatase activity
DM611_RS20910	COG3932	Exopolysaccharide synthesis, ExoD
DM611_RS20945	COG1999	signal sequence binding
DM611_RS20950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DM611_RS20955	COG1845	cytochrome c oxidase, subunit III
DM611_RS20965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DM611_RS20970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM611_RS20985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM611_RS20990	COG1104	cysteine desulfurase activity
DM611_RS21015	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DM611_RS21035	COG2031	fatty acid transporter
DM611_RS21055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM611_RS21065	COG0673	inositol 2-dehydrogenase activity
DM611_RS21075	COG1501	Belongs to the glycosyl hydrolase 31 family
DM611_RS21080	COG2222	sugar isomerase
DM611_RS21085	COG1940	carbohydrate kinase activity
DM611_RS21095	COG1349	DNA-binding transcription factor activity
DM611_RS21100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DM611_RS21105	COG2814	Major facilitator Superfamily
DM611_RS21120	COG1040	competence protein
DM611_RS21140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DM611_RS21145	COG0156	8-amino-7-oxononanoate synthase activity
DM611_RS21150	COG2267	carboxylic ester hydrolase activity
DM611_RS21155	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS21170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DM611_RS21195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM611_RS21200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM611_RS21205	COG2205	protein histidine kinase activity
DM611_RS21210	COG0745	RESPONSE REGULATOR receiver
DM611_RS21215	COG3541	Predicted nucleotidyltransferase
DM611_RS21220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DM611_RS21245	COG0714	Associated with various cellular activities
DM611_RS21255	COG0754	glutathionylspermidine amidase activity
DM611_RS21270	COG0129	dihydroxy-acid dehydratase activity
DM611_RS21275	COG2311	Membrane
DM611_RS21280	COG1199	ATP-dependent helicase activity
DM611_RS21290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DM611_RS21310	COG3781	membrane
DM611_RS21340	COG0625	glutathione transferase activity
DM611_RS21360	COG2207	Transcriptional regulator
DM611_RS21375	COG4555	ABC transporter
DM611_RS21500	COG4771	TonB-dependent receptor
DM611_RS21555	COG0543	2 iron, 2 sulfur cluster binding
DM611_RS21555	COG0633	Ferredoxin
DM611_RS21560	COG1131	(ABC) transporter
DM611_RS21565	COG0842	Transport permease protein
DM611_RS21575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DM611_RS21585	COG0084	hydrolase, TatD family'
DM611_RS21590	COG1643	Atp-dependent helicase
DM611_RS21600	COG1187	pseudouridine synthase activity
DM611_RS21615	COG0667	Aldo Keto reductase
DM611_RS21630	COG1690	Belongs to the RtcB family
DM611_RS21645	COG0840	transmembrane signaling receptor activity
DM611_RS21650	COG0583	DNA-binding transcription factor activity
DM611_RS21655	COG2814	Major facilitator Superfamily
DM611_RS21660	COG0656	L-ascorbic acid biosynthetic process
DM611_RS21665	COG2267	carboxylic ester hydrolase activity
DM611_RS21670	COG0393	Putative heavy-metal-binding
DM611_RS21675	COG0045	succinate-CoA ligase (ADP-forming) activity
DM611_RS21675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DM611_RS21675	COG1042	CoA-binding domain protein
DM611_RS21680	COG2239	Acts as a magnesium transporter
DM611_RS21695	COG0666	response to abiotic stimulus
DM611_RS21695	COG3177	Filamentation induced by cAMP protein fic
DM611_RS21700	COG3100	YcgL domain-containing protein
DM611_RS21710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DM611_RS21715	COG1028	Short-chain dehydrogenase reductase Sdr
DM611_RS21755	COG2986	histidine ammonia-lyase
DM611_RS21765	COG0463	Glycosyl transferase, family 2
DM611_RS21770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DM611_RS21780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DM611_RS21785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DM611_RS21800	COG1294	oxidase, subunit
DM611_RS21805	COG1271	oxidase subunit
DM611_RS21840	COG1595	DNA-templated transcription, initiation
DM611_RS21880	COG0408	coproporphyrinogen oxidase activity
DM611_RS21890	COG2323	membrane
DM611_RS21920	COG0515	serine threonine protein kinase
DM611_RS21920	COG2815	serine threonine protein kinase
DM611_RS21925	COG0631	protein serine/threonine phosphatase activity
DM611_RS22040	COG0589	response to stress
DM611_RS22060	COG0210	DNA helicase
DM611_RS22070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DM611_RS22075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DM611_RS22080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DM611_RS22095	COG0251	oxidation-reduction process
DM611_RS22140	COG0463	Glycosyl transferase, family 2
DM611_RS22155	COG1475	DNA binding
DM611_RS22160	COG1192	Involved in chromosome partitioning
DM611_RS22165	COG0357	Ribosomal RNA small subunit methyltransferase G
DM611_RS22170	COG2091	lysine biosynthetic process via aminoadipic acid
DM611_RS22210	COG1971	Probably functions as a manganese efflux pump
DM611_RS22215	COG2205	protein histidine kinase activity
DM611_RS22215	COG0784	Response regulator, receiver
DM611_RS22225	COG2911	Protein conserved in bacteria
DM611_RS22230	COG0729	surface antigen
DM611_RS22240	COG0752	glycyl-tRNA synthetase alpha subunit
DM611_RS22245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DM611_RS22250	COG0519	Catalyzes the synthesis of GMP from XMP
DM611_RS22250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DM611_RS22260	COG0805	protein transport
DM611_RS22270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DM611_RS22280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DM611_RS22290	COG0840	transmembrane signaling receptor activity
DM611_RS22345	COG3135	benzoate transporter
DM611_RS22360	COG2951	lytic endotransglycosylase activity
DM611_RS22365	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DM611_RS22370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DM611_RS22375	COG3706	GGDEF domain
DM611_RS22405	COG0302	gtp cyclohydrolase
DM611_RS22420	COG1566	PFAM secretion protein HlyD family protein
DM611_RS22430	COG1289	transmembrane transporter activity
DM611_RS22445	COG1074	ATP-dependent DNA helicase activity
DM611_RS22450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DM611_RS22455	COG1127	ABC transporter
DM611_RS22460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM611_RS22465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DM611_RS22480	COG2853	Lipoprotein
DM611_RS22485	COG0386	Belongs to the glutathione peroxidase family
DM611_RS22495	COG1322	Protein conserved in bacteria
DM611_RS22510	COG0583	DNA-binding transcription factor activity
DM611_RS22530	COG0531	amino acid
DM611_RS22540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DM611_RS22545	COG0861	Integral membrane protein TerC family
DM611_RS22555	COG0584	glycerophosphoryl diester phosphodiesterase
DM611_RS22570	COG0706	membrane insertase activity
DM611_RS22575	COG0594	ribonuclease P activity
DM611_RS22580	COG0230	Belongs to the bacterial ribosomal protein bL34 family