locus-tag	class	description
DUW70_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DUW70_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DUW70_RS00020	COG0187	DNA topoisomerase II activity
DUW70_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DUW70_RS00095	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DUW70_RS00105	COG4772	TonB-dependent receptor
DUW70_RS00140	COG0800	Aldolase
DUW70_RS00155	COG3186	Phenylalanine-4-hydroxylase
DUW70_RS00160	COG1522	sequence-specific DNA binding
DUW70_RS00170	COG1752	Esterase of the alpha-beta hydrolase superfamily
DUW70_RS00200	COG1122	ATPase activity
DUW70_RS00215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DUW70_RS00220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DUW70_RS00235	COG0210	DNA helicase
DUW70_RS00245	COG3132	Protein of unknown function, DUF480
DUW70_RS00250	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DUW70_RS00255	COG0284	orotidine-5'-phosphate decarboxylase activity
DUW70_RS00265	COG2937	Belongs to the GPAT DAPAT family
DUW70_RS00275	COG0037	tRNA processing
DUW70_RS00280	COG2974	May be involved in recombination
DUW70_RS00295	COG2205	protein histidine kinase activity
DUW70_RS00295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUW70_RS00300	COG0493	'glutamate synthase
DUW70_RS00305	COG0069	glutamate synthase activity
DUW70_RS00305	COG0070	glutamate synthase
DUW70_RS00305	COG0067	glutamate synthase
DUW70_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS00390	COG1205	dead DEAH box helicase
DUW70_RS00390	COG1111	helicase
DUW70_RS00425	COG0714	Associated with various cellular activities
DUW70_RS00445	COG0312	modulator of DNA gyrase
DUW70_RS00460	COG3550	peptidyl-serine autophosphorylation
DUW70_RS00485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DUW70_RS00505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DUW70_RS00540	COG1968	undecaprenyl-diphosphatase activity
DUW70_RS00545	COG0174	glutamine synthetase
DUW70_RS00550	COG0347	Belongs to the P(II) protein family
DUW70_RS00555	COG0004	ammonium transporteR
DUW70_RS00565	COG3279	Response regulator of the LytR AlgR family
DUW70_RS00580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DUW70_RS00600	COG3852	Histidine kinase
DUW70_RS00605	COG2204	response regulator
DUW70_RS00610	COG2032	superoxide dismutase activity
DUW70_RS00615	COG2032	superoxide dismutase activity
DUW70_RS00625	COG0183	Belongs to the thiolase family
DUW70_RS00660	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DUW70_RS00665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DUW70_RS00680	COG3550	peptidyl-serine autophosphorylation
DUW70_RS00705	COG0210	DNA helicase
DUW70_RS00710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DUW70_RS00780	COG0633	Ferredoxin
DUW70_RS00785	COG0789	Transcriptional regulator
DUW70_RS00795	COG0640	Transcriptional regulator
DUW70_RS00800	COG2814	Major facilitator Superfamily
DUW70_RS00805	COG1937	Protein conserved in bacteria
DUW70_RS00810	COG1230	cation diffusion facilitator family transporter
DUW70_RS00815	COG0640	Transcriptional regulator
DUW70_RS00820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS00840	COG2814	Major facilitator Superfamily
DUW70_RS00850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DUW70_RS00875	COG2837	iron assimilation
DUW70_RS00915	COG2197	response regulator
DUW70_RS00920	COG2205	protein histidine kinase activity
DUW70_RS00920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUW70_RS00925	COG3474	cytochrome
DUW70_RS00935	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS00940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DUW70_RS00950	COG0612	Peptidase, M16
DUW70_RS00960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUW70_RS00965	COG0596	Alpha beta hydrolase
DUW70_RS00975	COG0318	PFAM AMP-dependent synthetase and ligase
DUW70_RS00980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DUW70_RS00990	COG1181	Belongs to the D-alanine--D-alanine ligase family
DUW70_RS01000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DUW70_RS01030	COG0339	signal peptide processing
DUW70_RS01045	COG0681	Belongs to the peptidase S26 family
DUW70_RS01050	COG2814	Major facilitator Superfamily
DUW70_RS01055	COG0583	DNA-binding transcription factor activity
DUW70_RS01065	COG0583	DNA-binding transcription factor activity
DUW70_RS01070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DUW70_RS01075	COG2224	Isocitrate lyase
DUW70_RS01080	COG3706	GGDEF domain
DUW70_RS01105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUW70_RS01110	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS01130	COG0697	spore germination
DUW70_RS01140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DUW70_RS01160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DUW70_RS01165	COG1280	lysine exporter protein (LysE YggA)
DUW70_RS01170	COG1607	acyl-coa hydrolase
DUW70_RS01180	COG1902	pentaerythritol trinitrate reductase activity
DUW70_RS01195	COG1335	isochorismatase
DUW70_RS01200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DUW70_RS01205	COG1752	Esterase of the alpha-beta hydrolase superfamily
DUW70_RS01215	COG3800	Transcriptional regulator
DUW70_RS01215	COG1396	sequence-specific DNA binding
DUW70_RS01225	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS01230	COG1024	Enoyl-CoA hydratase
DUW70_RS01235	COG1024	Enoyl-CoA hydratase
DUW70_RS01245	COG1764	response to oxidative stress
DUW70_RS01255	COG0659	secondary active sulfate transmembrane transporter activity
DUW70_RS01265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DUW70_RS01285	COG3228	Belongs to the MtfA family
DUW70_RS01295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DUW70_RS01295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DUW70_RS01300	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DUW70_RS01370	COG0305	Participates in initiation and elongation during chromosome replication
DUW70_RS01560	COG3237	CsbD-like
DUW70_RS01570	COG0180	Tryptophanyl-tRNA synthetase
DUW70_RS01595	COG0477	Major facilitator Superfamily
DUW70_RS01600	COG0697	spore germination
DUW70_RS01615	COG0577	efflux transmembrane transporter activity
DUW70_RS01615	COG1136	(ABC) transporter
DUW70_RS01625	COG1136	(ABC) transporter
DUW70_RS01645	COG4585	Histidine kinase
DUW70_RS01650	COG2197	response regulator
DUW70_RS01665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DUW70_RS01675	COG0628	permease
DUW70_RS01695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUW70_RS01710	COG5507	3-demethylubiquinone-9 3-methyltransferase
DUW70_RS01715	COG0823	Involved in the tonB-independent uptake of proteins
DUW70_RS01715	COG1506	peptidase
DUW70_RS01725	COG2197	response regulator
DUW70_RS01740	COG2814	Major facilitator Superfamily
DUW70_RS01745	COG0583	DNA-binding transcription factor activity
DUW70_RS01750	COG4807	Protein conserved in bacteria
DUW70_RS01755	COG4221	oxidoreductase activity
DUW70_RS01770	COG0018	arginyl-trna synthetase
DUW70_RS01775	COG2003	Belongs to the UPF0758 family
DUW70_RS01780	COG2197	response regulator
DUW70_RS01785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DUW70_RS01790	COG0756	dUTP diphosphatase activity
DUW70_RS01805	COG2205	protein histidine kinase activity
DUW70_RS01815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DUW70_RS01820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DUW70_RS01835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DUW70_RS01840	COG0582	viral genome integration into host DNA
DUW70_RS01910	COG0305	Participates in initiation and elongation during chromosome replication
DUW70_RS02105	COG0708	Exodeoxyribonuclease III
DUW70_RS02110	COG2223	nitrite transmembrane transporter activity
DUW70_RS02125	COG0739	heme binding
DUW70_RS02130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DUW70_RS02190	COG2234	aminopeptidase activity
DUW70_RS02200	COG4942	peptidase
DUW70_RS02205	COG0793	Belongs to the peptidase S41A family
DUW70_RS02235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DUW70_RS02240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DUW70_RS02280	COG0109	protoheme IX farnesyltransferase activity
DUW70_RS02305	COG0358	DNA primase activity
DUW70_RS02310	COG1295	ribonuclease BN
DUW70_RS02325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DUW70_RS02335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DUW70_RS02340	COG0668	transmembrane transport
DUW70_RS02355	COG2133	pyrroloquinoline quinone binding
DUW70_RS02360	COG4682	membrane
DUW70_RS02370	COG0531	amino acid
DUW70_RS02380	COG1737	Transcriptional regulator
DUW70_RS02385	COG4948	Mandelate Racemase Muconate Lactonizing
DUW70_RS02435	COG5383	Protein conserved in bacteria
DUW70_RS02445	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DUW70_RS02455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DUW70_RS02485	COG0778	Nitroreductase
DUW70_RS02490	COG2353	YceI-like domain
DUW70_RS02505	COG2375	cellular response to nickel ion
DUW70_RS02590	COG2267	carboxylic ester hydrolase activity
DUW70_RS02655	COG0488	(ABC) transporter
DUW70_RS02660	COG0583	DNA-binding transcription factor activity
DUW70_RS02670	COG2814	Major facilitator Superfamily
DUW70_RS02675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DUW70_RS02680	COG1113	amino acid transport
DUW70_RS02685	COG0741	lytic transglycosylase activity
DUW70_RS02710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DUW70_RS02720	COG5507	3-demethylubiquinone-9 3-methyltransferase
DUW70_RS02725	COG4941	Belongs to the sigma-70 factor family
DUW70_RS02755	COG3275	phosphorelay sensor kinase activity
DUW70_RS02760	COG3279	Response regulator of the LytR AlgR family
DUW70_RS02780	COG1309	transcriptional regulator
DUW70_RS02790	COG2814	Major facilitator Superfamily
DUW70_RS02795	COG3590	peptidase
DUW70_RS02800	COG5001	Diguanylate cyclase
DUW70_RS02805	COG0583	DNA-binding transcription factor activity
DUW70_RS02815	COG3384	dioxygenase
DUW70_RS02820	COG0025	NhaP-type Na H and K H
DUW70_RS02850	COG1360	Flagellar Motor Protein
DUW70_RS02880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DUW70_RS02895	COG0784	Response regulator, receiver
DUW70_RS02895	COG2205	protein histidine kinase activity
DUW70_RS02910	COG2813	Specifically methylates the guanine in position
DUW70_RS02915	COG1187	pseudouridine synthase activity
DUW70_RS02920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DUW70_RS02930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DUW70_RS02935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DUW70_RS02950	COG0583	DNA-binding transcription factor activity
DUW70_RS02955	COG2226	methyltransferase
DUW70_RS02980	COG1956	GAF domain-containing protein
DUW70_RS02985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DUW70_RS03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUW70_RS03005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DUW70_RS03010	COG0785	Cytochrome C biogenesis protein
DUW70_RS03010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS03015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DUW70_RS03020	COG0745	RESPONSE REGULATOR receiver
DUW70_RS03025	COG5002	protein histidine kinase activity
DUW70_RS03030	COG2205	protein histidine kinase activity
DUW70_RS03035	COG0745	RESPONSE REGULATOR receiver
DUW70_RS03040	COG0367	asparagine synthase
DUW70_RS03050	COG0720	synthase
DUW70_RS03065	COG0513	Belongs to the DEAD box helicase family
DUW70_RS03075	COG0625	glutathione transferase activity
DUW70_RS03080	COG1573	uracil-dna glycosylase
DUW70_RS03115	COG0626	cystathionine gamma-synthase activity
DUW70_RS03130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DUW70_RS03135	COG0297	glycogen (starch) synthase activity
DUW70_RS03140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DUW70_RS03205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DUW70_RS03210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUW70_RS03240	COG1127	ABC transporter
DUW70_RS03245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DUW70_RS03260	COG0442	prolyl-tRNA aminoacylation
DUW70_RS03270	COG1183	phosphatidylcholine synthase activity
DUW70_RS03280	COG0456	acetyltransferase
DUW70_RS03290	COG0525	valine-tRNA ligase activity
DUW70_RS03305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DUW70_RS03315	COG0795	lipopolysaccharide-transporting ATPase activity
DUW70_RS03330	COG4974	Belongs to the 'phage' integrase family
DUW70_RS03335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DUW70_RS03345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DUW70_RS03345	COG0047	phosphoribosylformylglycinamidine synthase activity
DUW70_RS03350	COG5295	Hep Hag repeat protein
DUW70_RS03360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DUW70_RS03365	COG1459	type II secretion system
DUW70_RS03370	COG2165	general secretion pathway protein
DUW70_RS03375	COG4970	Tfp pilus assembly protein FimT
DUW70_RS03380	COG2165	general secretion pathway protein
DUW70_RS03385	COG4795	General secretion pathway protein
DUW70_RS03390	COG3156	type II secretion system protein K
DUW70_RS03395	COG3166	PFAM Fimbrial assembly family protein
DUW70_RS03410	COG1450	Type ii and iii secretion system protein
DUW70_RS03420	COG0463	Glycosyl transferase, family 2
DUW70_RS03435	COG3539	Fimbrial protein
DUW70_RS03455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DUW70_RS03465	COG1215	transferase activity, transferring glycosyl groups
DUW70_RS03480	COG2252	PERMEase
DUW70_RS03485	COG0488	(ABC) transporter
DUW70_RS03495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DUW70_RS03510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DUW70_RS03515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DUW70_RS03515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DUW70_RS03545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DUW70_RS03550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DUW70_RS03565	COG0277	FAD linked oxidase domain protein
DUW70_RS03570	COG1988	membrane-bound metal-dependent
DUW70_RS03615	COG2001	Belongs to the MraZ family
DUW70_RS03620	COG0275	rRNA processing
DUW70_RS03625	COG3116	cell division
DUW70_RS03635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DUW70_RS03640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DUW70_RS03660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DUW70_RS03665	COG1181	Belongs to the D-alanine--D-alanine ligase family
DUW70_RS03670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DUW70_RS03680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DUW70_RS03685	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DUW70_RS03695	COG0739	heme binding
DUW70_RS03700	COG0653	protein targeting
DUW70_RS03705	COG0494	nUDIX hydrolase
DUW70_RS03715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DUW70_RS03725	COG3275	phosphorelay sensor kinase activity
DUW70_RS03730	COG3279	Response regulator of the LytR AlgR family
DUW70_RS03755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DUW70_RS03760	COG2357	RelA SpoT domain protein
DUW70_RS03765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DUW70_RS03775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DUW70_RS03780	COG1607	acyl-coa hydrolase
DUW70_RS03785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DUW70_RS03810	COG4106	trans-aconitate 2-methyltransferase activity
DUW70_RS03815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DUW70_RS03825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUW70_RS03830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DUW70_RS03835	COG0667	Aldo Keto reductase
DUW70_RS03845	COG4771	TonB-dependent receptor
DUW70_RS03865	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DUW70_RS03870	COG4181	ATPase activity
DUW70_RS03885	COG0642	Histidine kinase
DUW70_RS03895	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DUW70_RS03900	COG0861	Integral membrane protein TerC family
DUW70_RS03905	COG2814	Major facilitator Superfamily
DUW70_RS03910	COG1704	LemA family
DUW70_RS03925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DUW70_RS03930	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DUW70_RS03945	COG3738	Protein conserved in bacteria
DUW70_RS03950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DUW70_RS03955	COG2967	ApaG domain
DUW70_RS03960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DUW70_RS03965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DUW70_RS03970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DUW70_RS03975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DUW70_RS03985	COG2096	Adenosyltransferase
DUW70_RS03995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUW70_RS04000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUW70_RS04005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DUW70_RS04010	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DUW70_RS04030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DUW70_RS04040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DUW70_RS04050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DUW70_RS04055	COG0583	DNA-binding transcription factor activity
DUW70_RS04060	COG3634	alkyl hydroperoxide reductase activity
DUW70_RS04080	COG0583	DNA-binding transcription factor activity
DUW70_RS04120	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DUW70_RS04145	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DUW70_RS04160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DUW70_RS04180	COG1404	Belongs to the peptidase S8 family
DUW70_RS04200	COG1295	ribonuclease BN
DUW70_RS04205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS04225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DUW70_RS04230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DUW70_RS04245	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DUW70_RS04255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DUW70_RS04260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DUW70_RS04265	COG0193	aminoacyl-tRNA hydrolase activity
DUW70_RS04270	COG0012	GTP binding
DUW70_RS04275	COG4206	TonB-dependent receptor
DUW70_RS04280	COG4242	Belongs to the peptidase S51 family
DUW70_RS04305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DUW70_RS04320	COG0250	Participates in transcription elongation, termination and antitermination
DUW70_RS04325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DUW70_RS04330	COG0081	regulation of translation
DUW70_RS04335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DUW70_RS04340	COG0222	ribosome binding
DUW70_RS04345	COG0085	RNA polymerase activity
DUW70_RS04350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DUW70_RS04355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DUW70_RS04360	COG0049	tRNA binding
DUW70_RS04365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DUW70_RS04370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DUW70_RS04375	COG0051	transcription antitermination factor activity, RNA binding
DUW70_RS04380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DUW70_RS04385	COG0088	Forms part of the polypeptide exit tunnel
DUW70_RS04390	COG0089	rRNA binding
DUW70_RS04395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DUW70_RS04400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DUW70_RS04405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DUW70_RS04410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DUW70_RS04415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DUW70_RS04420	COG0255	Belongs to the universal ribosomal protein uL29 family
DUW70_RS04425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DUW70_RS04430	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DUW70_RS04435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DUW70_RS04440	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DUW70_RS04445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DUW70_RS04450	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DUW70_RS04455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DUW70_RS04460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DUW70_RS04465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DUW70_RS04470	COG1841	ribosomal large subunit assembly
DUW70_RS04475	COG0200	Binds to the 23S rRNA
DUW70_RS04480	COG0201	protein transport
DUW70_RS04485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DUW70_RS04490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DUW70_RS04495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DUW70_RS04500	COG0202	RNA polymerase activity
DUW70_RS04505	COG0203	ribosomal protein L17
DUW70_RS04520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DUW70_RS04530	COG0154	amidase activity
DUW70_RS04545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DUW70_RS04550	COG0039	L-malate dehydrogenase activity
DUW70_RS04555	COG0564	pseudouridine synthase activity
DUW70_RS04560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUW70_RS04575	COG0625	glutathione transferase activity
DUW70_RS04585	COG1902	pentaerythritol trinitrate reductase activity
DUW70_RS04585	COG0446	pyridine nucleotide-disulphide oxidoreductase
DUW70_RS04590	COG2364	Membrane
DUW70_RS04595	COG0604	alcohol dehydrogenase
DUW70_RS04610	COG1187	pseudouridine synthase activity
DUW70_RS04630	COG1063	alcohol dehydrogenase
DUW70_RS04640	COG0588	phosphoglycerate mutase activity
DUW70_RS04645	COG0285	dihydrofolate synthase activity
DUW70_RS04665	COG2833	Protein of unknown function (DUF455)
DUW70_RS04675	COG3291	Pkd domain containing protein
DUW70_RS04680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DUW70_RS04690	COG0438	transferase activity, transferring glycosyl groups
DUW70_RS04700	COG4206	TonB-dependent receptor
DUW70_RS04705	COG0248	Ppx GppA phosphatase
DUW70_RS04710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DUW70_RS04725	COG4783	chaperone-mediated protein folding
DUW70_RS04740	COG0473	3-isopropylmalate dehydrogenase activity
DUW70_RS04815	COG0544	peptidyl-prolyl cis-trans isomerase activity
DUW70_RS04820	COG0740	serine-type endopeptidase activity
DUW70_RS04825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DUW70_RS04865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DUW70_RS04870	COG1388	LysM domain
DUW70_RS04870	COG3942	CHAP domain
DUW70_RS04875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUW70_RS04885	COG0328	RNA-DNA hybrid ribonuclease activity
DUW70_RS04890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DUW70_RS04895	COG0631	protein serine/threonine phosphatase activity
DUW70_RS04910	COG0859	PFAM glycosyl transferase family 9
DUW70_RS04915	COG3642	lipopolysaccharide core region biosynthetic process
DUW70_RS04920	COG1234	tRNA 3'-trailer cleavage
DUW70_RS04935	COG2076	Multidrug Resistance protein
DUW70_RS04960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DUW70_RS04965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DUW70_RS04975	COG0537	adenosine 5'-monophosphoramidase activity
DUW70_RS04995	COG0714	Associated with various cellular activities
DUW70_RS05010	COG1399	metal-binding, possibly nucleic acid-binding protein
DUW70_RS05015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DUW70_RS05020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUW70_RS05030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DUW70_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS05045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUW70_RS05050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DUW70_RS05055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DUW70_RS05060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DUW70_RS05140	COG0582	viral genome integration into host DNA
DUW70_RS05160	COG4774	siderophore transport
DUW70_RS05170	COG2223	nitrite transmembrane transporter activity
DUW70_RS05195	COG0583	DNA-binding transcription factor activity
DUW70_RS05200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUW70_RS05205	COG0697	spore germination
DUW70_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS05215	COG0583	DNA-binding transcription factor activity
DUW70_RS05225	COG0477	Major facilitator Superfamily
DUW70_RS05235	COG2205	protein histidine kinase activity
DUW70_RS05285	COG0583	DNA-binding transcription factor activity
DUW70_RS05295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DUW70_RS05310	COG0667	Aldo Keto reductase
DUW70_RS05325	COG0456	acetyltransferase
DUW70_RS05335	COG2818	Glycosylase
DUW70_RS05340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DUW70_RS05345	COG1678	Uncharacterized ACR, COG1678
DUW70_RS05350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DUW70_RS05355	COG0540	Belongs to the ATCase OTCase family
DUW70_RS05375	COG2239	Acts as a magnesium transporter
DUW70_RS05380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DUW70_RS05395	COG1660	Displays ATPase and GTPase activities
DUW70_RS05400	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DUW70_RS05405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DUW70_RS05410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DUW70_RS05420	COG1137	ATPase activity
DUW70_RS05435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DUW70_RS05450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DUW70_RS05470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DUW70_RS05490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DUW70_RS05500	COG0628	permease
DUW70_RS05510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DUW70_RS05520	COG2261	transglycosylase associated protein
DUW70_RS05530	COG1555	photosystem II stabilization
DUW70_RS05550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DUW70_RS05555	COG1477	protein flavinylation
DUW70_RS05575	COG4771	TonB-dependent receptor
DUW70_RS05585	COG3128	pkhd-type hydroxylase
DUW70_RS05640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DUW70_RS05645	COG0719	Fe-S assembly protein
DUW70_RS05650	COG0396	ATPase activity
DUW70_RS05655	COG0719	Fe-S assembly protein
DUW70_RS05660	COG1959	2 iron, 2 sulfur cluster binding
DUW70_RS05690	COG1764	response to oxidative stress
DUW70_RS05695	COG0384	phenazine biosynthesis protein PhzF
DUW70_RS05700	COG0384	phenazine biosynthesis protein PhzF
DUW70_RS05715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DUW70_RS05730	COG0142	geranyltranstransferase activity
DUW70_RS05735	COG0366	Alpha amylase catalytic
DUW70_RS05745	COG1082	Xylose isomerase domain protein TIM barrel
DUW70_RS05755	COG2211	Major facilitator Superfamily
DUW70_RS05755	COG2190	(PTS) system
DUW70_RS05790	COG1131	(ABC) transporter
DUW70_RS05805	COG0629	single-stranded DNA binding
DUW70_RS05910	COG2010	Cytochrome c
DUW70_RS05920	COG0673	inositol 2-dehydrogenase activity
DUW70_RS05925	COG2211	Major facilitator Superfamily
DUW70_RS05935	COG1609	Transcriptional regulator
DUW70_RS05945	COG0583	DNA-binding transcription factor activity
DUW70_RS05985	COG3655	Transcriptional regulator
DUW70_RS05990	COG1253	flavin adenine dinucleotide binding
DUW70_RS05995	COG1408	metallophosphoesterase
DUW70_RS06010	COG0477	Major facilitator Superfamily
DUW70_RS06025	COG1802	Transcriptional regulator
DUW70_RS06060	COG3052	prosthetic group binding
DUW70_RS06075	COG0579	oxidoreductase
DUW70_RS06100	COG3104	oligopeptide transport
DUW70_RS06110	COG1297	OPT oligopeptide transporter protein
DUW70_RS06115	COG1506	peptidase
DUW70_RS06115	COG0823	Involved in the tonB-independent uptake of proteins
DUW70_RS06130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DUW70_RS06135	COG2894	cell division
DUW70_RS06140	COG0850	regulation of cytokinetic process
DUW70_RS06150	COG4585	Histidine kinase
DUW70_RS06155	COG2197	response regulator
DUW70_RS06195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DUW70_RS06205	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DUW70_RS06215	COG1595	DNA-templated transcription, initiation
DUW70_RS06225	COG1946	Acyl-CoA thioesterase
DUW70_RS06245	COG0824	Thioesterase
DUW70_RS06250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DUW70_RS06255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DUW70_RS06260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DUW70_RS06265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DUW70_RS06270	COG0268	Binds directly to 16S ribosomal RNA
DUW70_RS06280	COG0196	riboflavin kinase activity
DUW70_RS06285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DUW70_RS06295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DUW70_RS06320	COG4206	TonB-dependent receptor
DUW70_RS06340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DUW70_RS06370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DUW70_RS06375	COG1845	cytochrome c oxidase, subunit III
DUW70_RS06380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DUW70_RS06395	COG0326	Molecular chaperone. Has ATPase activity
DUW70_RS06415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DUW70_RS06435	COG0228	four-way junction DNA binding
DUW70_RS06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DUW70_RS06445	COG0336	Belongs to the RNA methyltransferase TrmD family
DUW70_RS06450	COG0335	large ribosomal subunit rRNA binding
DUW70_RS06470	COG0534	Mate efflux family protein
DUW70_RS06495	COG0753	catalase activity
DUW70_RS06520	COG0840	transmembrane signaling receptor activity
DUW70_RS06540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS06565	COG0024	Methionine aminopeptidase
DUW70_RS06590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DUW70_RS06615	COG1647	Serine aminopeptidase, S33
DUW70_RS06640	COG2814	Major facilitator Superfamily
DUW70_RS06645	COG3706	GGDEF domain
DUW70_RS06665	COG0588	phosphoglycerate mutase activity
DUW70_RS06695	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS06705	COG1309	transcriptional regulator
DUW70_RS06710	COG4206	TonB-dependent receptor
DUW70_RS06720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DUW70_RS06725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUW70_RS06730	COG0463	Glycosyl transferase, family 2
DUW70_RS06745	COG1272	protein, Hemolysin III
DUW70_RS06750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DUW70_RS06755	COG0739	heme binding
DUW70_RS06760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DUW70_RS06765	COG0626	cystathionine gamma-synthase activity
DUW70_RS06770	COG0527	aspartate kinase activity
DUW70_RS06770	COG0460	homoserine dehydrogenase
DUW70_RS06775	COG2267	carboxylic ester hydrolase activity
DUW70_RS06780	COG1760	l-serine dehydratase
DUW70_RS06795	COG3038	cytochrome b561
DUW70_RS06815	COG0477	Major facilitator Superfamily
DUW70_RS06835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DUW70_RS06850	COG0259	pyridoxamine-phosphate oxidase activity
DUW70_RS06880	COG3609	addiction module antidote protein, CC2985 family
DUW70_RS06890	COG2828	Protein conserved in bacteria
DUW70_RS06895	COG2079	MmgE PrpD family protein
DUW70_RS06900	COG2373	Large extracellular alpha-helical protein
DUW70_RS06905	COG4953	penicillin-binding protein 1C
DUW70_RS06915	COG0678	peroxiredoxin activity
DUW70_RS06930	COG0604	alcohol dehydrogenase
DUW70_RS06935	COG0330	HflC and HflK could
DUW70_RS06940	COG0330	HflC and HflK could
DUW70_RS06950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DUW70_RS06960	COG0739	heme binding
DUW70_RS06965	COG1376	ErfK ybiS ycfS ynhG family protein
DUW70_RS06995	COG0753	catalase activity
DUW70_RS07005	COG1113	amino acid transport
DUW70_RS07015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DUW70_RS07015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DUW70_RS07020	COG2814	Major facilitator Superfamily
DUW70_RS07055	COG0745	RESPONSE REGULATOR receiver
DUW70_RS07060	COG2205	protein histidine kinase activity
DUW70_RS07075	COG2879	small protein
DUW70_RS07080	COG1966	Carbon starvation protein
DUW70_RS07085	COG1741	Belongs to the pirin family
DUW70_RS07095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DUW70_RS07100	COG1741	Belongs to the pirin family
DUW70_RS07120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUW70_RS07125	COG0481	GTPase activity
DUW70_RS07130	COG0681	Belongs to the peptidase S26 family
DUW70_RS07145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DUW70_RS07150	COG1381	Involved in DNA repair and RecF pathway recombination
DUW70_RS07155	COG0745	RESPONSE REGULATOR receiver
DUW70_RS07160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DUW70_RS07165	COG2954	triphosphatase activity
DUW70_RS07170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DUW70_RS07175	COG1472	Belongs to the glycosyl hydrolase 3 family
DUW70_RS07180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DUW70_RS07185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DUW70_RS07190	COG1278	Cold shock
DUW70_RS07210	COG1201	RNA secondary structure unwinding
DUW70_RS07215	COG1793	dna ligase
DUW70_RS07225	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS07240	COG0183	Belongs to the thiolase family
DUW70_RS07260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DUW70_RS07270	COG1451	nucleotide metabolic process
DUW70_RS07275	COG3122	Protein conserved in bacteria
DUW70_RS07280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DUW70_RS07320	COG0443	Heat shock 70 kDa protein
DUW70_RS07325	COG2824	Alkylphosphonate utilization operon protein PhnA
DUW70_RS07355	COG0392	lysyltransferase activity
DUW70_RS07355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DUW70_RS07360	COG0251	oxidation-reduction process
DUW70_RS07365	COG2878	Part of a membrane complex involved in electron transport
DUW70_RS07375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DUW70_RS07375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DUW70_RS07385	COG0346	lactoylglutathione lyase activity
DUW70_RS07390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DUW70_RS07400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DUW70_RS07420	COG1943	Transposase
DUW70_RS07430	COG2203	Gaf domain
DUW70_RS07430	COG4251	negative regulation of phosphorylation
DUW70_RS07430	COG5001	Diguanylate cyclase
DUW70_RS07430	COG3706	GGDEF domain
DUW70_RS07440	COG3118	belongs to the thioredoxin family
DUW70_RS07450	COG0495	leucyl-tRNA aminoacylation
DUW70_RS07465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DUW70_RS07475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DUW70_RS07490	COG4771	TonB-dependent receptor
DUW70_RS07500	COG2968	Membrane
DUW70_RS07520	COG0312	modulator of DNA gyrase
DUW70_RS07525	COG3028	Belongs to the UPF0307 family
DUW70_RS07530	COG0312	modulator of DNA gyrase
DUW70_RS07540	COG0142	geranyltranstransferase activity
DUW70_RS07545	COG1722	exodeoxyribonuclease VII activity
DUW70_RS07565	COG1301	dicarboxylic acid transport
DUW70_RS07570	COG0791	NLP P60 protein
DUW70_RS07575	COG0791	NLP P60 protein
DUW70_RS07580	COG1047	Peptidyl-prolyl cis-trans
DUW70_RS07585	COG2311	Membrane
DUW70_RS07590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DUW70_RS07605	COG0697	spore germination
DUW70_RS07635	COG3590	peptidase
DUW70_RS07640	COG4771	TonB-dependent receptor
DUW70_RS07650	COG4771	TonB-dependent receptor
DUW70_RS07655	COG4771	TonB-dependent receptor
DUW70_RS07660	COG0489	protein tyrosine kinase activity
DUW70_RS07665	COG0717	Belongs to the dCTP deaminase family
DUW70_RS07680	COG0412	Dienelactone hydrolase
DUW70_RS07685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DUW70_RS07695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DUW70_RS07700	COG0433	COG0433 Predicted ATPase
DUW70_RS07715	COG0688	phosphatidylethanolamine metabolic process
DUW70_RS07720	COG1999	signal sequence binding
DUW70_RS07725	COG2890	protein-(glutamine-N5) methyltransferase activity
DUW70_RS07730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DUW70_RS07740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DUW70_RS07755	COG0101	tRNA pseudouridine synthase activity
DUW70_RS07760	COG0135	phosphoribosylanthranilate isomerase activity
DUW70_RS07780	COG0133	tryptophan synthase activity
DUW70_RS07790	COG0159	tryptophan synthase activity
DUW70_RS07795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DUW70_RS07800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DUW70_RS07805	COG0726	polysaccharide deacetylase
DUW70_RS07810	COG0438	transferase activity, transferring glycosyl groups
DUW70_RS07815	COG3119	arylsulfatase activity
DUW70_RS07825	COG0149	triose-phosphate isomerase activity
DUW70_RS07840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUW70_RS07845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUW70_RS07850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUW70_RS07855	COG0649	NAD binding
DUW70_RS07860	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DUW70_RS07875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DUW70_RS07880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUW70_RS07890	COG0713	ATP synthesis coupled electron transport
DUW70_RS07905	COG1007	ATP synthesis coupled electron transport
DUW70_RS07920	COG0779	Required for maturation of 30S ribosomal subunits
DUW70_RS07925	COG0195	Participates in both transcription termination and antitermination
DUW70_RS07930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DUW70_RS07935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DUW70_RS07945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DUW70_RS07950	COG1185	polyribonucleotide nucleotidyltransferase activity
DUW70_RS07980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DUW70_RS07985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DUW70_RS07990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DUW70_RS07995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DUW70_RS08000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DUW70_RS08010	COG0776	regulation of translation
DUW70_RS08050	COG1794	racemase activity, acting on amino acids and derivatives
DUW70_RS08065	COG0740	serine-type endopeptidase activity
DUW70_RS08070	COG1280	lysine exporter protein (LysE YggA)
DUW70_RS08075	COG5487	UPF0391 membrane protein
DUW70_RS08080	COG2076	Multidrug Resistance protein
DUW70_RS08085	COG1309	transcriptional regulator
DUW70_RS08115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DUW70_RS08125	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS08155	COG2130	NADP-dependent
DUW70_RS08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DUW70_RS08160	COG2169	Transcriptional regulator
DUW70_RS08185	COG4771	TonB-dependent receptor
DUW70_RS08200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DUW70_RS08210	COG1570	exodeoxyribonuclease VII activity
DUW70_RS08215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DUW70_RS08220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DUW70_RS08220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DUW70_RS08225	COG0802	atpase or kinase
DUW70_RS08230	COG0860	N-Acetylmuramoyl-L-alanine amidase
DUW70_RS08235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DUW70_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS08265	COG0501	Belongs to the peptidase M48B family
DUW70_RS08270	COG0483	inositol monophosphate 1-phosphatase activity
DUW70_RS08285	COG3300	MHYT domain
DUW70_RS08285	COG5001	Diguanylate cyclase
DUW70_RS08290	COG1509	lysine 2,3-aminomutase activity
DUW70_RS08295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DUW70_RS08300	COG0402	S-adenosylhomocysteine deaminase activity
DUW70_RS08305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DUW70_RS08325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DUW70_RS08350	COG2166	iron-sulfur cluster assembly
DUW70_RS08365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DUW70_RS08370	COG0137	argininosuccinate synthase activity
DUW70_RS08375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUW70_RS08380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DUW70_RS08390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DUW70_RS08395	COG0165	Argininosuccinate lyase
DUW70_RS08410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DUW70_RS08420	COG1215	transferase activity, transferring glycosyl groups
DUW70_RS08425	COG0726	polysaccharide deacetylase
DUW70_RS08425	COG1649	PFAM Uncharacterised BCR, COG1649
DUW70_RS08455	COG1294	oxidase, subunit
DUW70_RS08465	COG4988	ABC transporter
DUW70_RS08470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DUW70_RS08480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DUW70_RS08490	COG4235	cytochrome complex assembly
DUW70_RS08490	COG3088	subunit of a heme lyase
DUW70_RS08505	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DUW70_RS08525	COG4133	protoheme IX ABC transporter activity
DUW70_RS08530	COG0436	Aminotransferase
DUW70_RS08555	COG2814	Major facilitator Superfamily
DUW70_RS08565	COG1187	pseudouridine synthase activity
DUW70_RS08570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DUW70_RS08575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DUW70_RS08580	COG2350	Protein conserved in bacteria
DUW70_RS08585	COG0271	Belongs to the BolA IbaG family
DUW70_RS08615	COG0395	ABC-type sugar transport system, permease component
DUW70_RS08630	COG1530	ribonuclease E activity
DUW70_RS08640	COG0428	transporter
DUW70_RS08650	COG2154	pterin-4-alpha-carbinolamine dehydratase
DUW70_RS08655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DUW70_RS08655	COG0316	Belongs to the HesB IscA family
DUW70_RS08670	COG4290	ribonuclease
DUW70_RS08675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DUW70_RS08685	COG3104	oligopeptide transport
DUW70_RS08690	COG0705	Rhomboid family
DUW70_RS08710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DUW70_RS08715	COG0339	signal peptide processing
DUW70_RS08720	COG0386	Belongs to the glutathione peroxidase family
DUW70_RS08740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUW70_RS08745	COG1595	DNA-templated transcription, initiation
DUW70_RS08765	COG0625	glutathione transferase activity
DUW70_RS08800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DUW70_RS08805	COG0084	hydrolase, TatD family'
DUW70_RS08825	COG0625	glutathione transferase activity
DUW70_RS08845	COG0305	Participates in initiation and elongation during chromosome replication
DUW70_RS08855	COG3540	Alkaline phosphatase
DUW70_RS08880	COG0567	Dehydrogenase, E1 component
DUW70_RS08900	COG0114	fumarate hydratase activity
DUW70_RS08925	COG1131	(ABC) transporter
DUW70_RS08930	COG1725	Transcriptional regulator
DUW70_RS08935	COG0386	Belongs to the glutathione peroxidase family
DUW70_RS08950	COG2900	Belongs to the SlyX family
DUW70_RS08960	COG2755	lipolytic protein G-D-S-L family
DUW70_RS08960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DUW70_RS08965	COG1410	methionine synthase
DUW70_RS08965	COG0646	methionine synthase
DUW70_RS08980	COG1960	acyl-CoA dehydrogenase activity
DUW70_RS08990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS08995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS09005	COG2902	Dehydrogenase
DUW70_RS09025	COG0667	Aldo Keto reductase
DUW70_RS09035	COG2925	Exonuclease
DUW70_RS09040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUW70_RS09045	COG3844	kynureninase activity
DUW70_RS09055	COG0288	reversible hydration of carbon dioxide
DUW70_RS09075	COG0017	Asparaginyl-tRNA synthetase
DUW70_RS09080	COG0316	Belongs to the HesB IscA family
DUW70_RS09090	COG0360	Binds together with S18 to 16S ribosomal RNA
DUW70_RS09095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DUW70_RS09100	COG0359	binds to the 23S rRNA
DUW70_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DUW70_RS09120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DUW70_RS09130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DUW70_RS09140	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DUW70_RS09230	COG0583	DNA-binding transcription factor activity
DUW70_RS09235	COG2957	Belongs to the agmatine deiminase family
DUW70_RS09290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DUW70_RS09305	COG1228	amidohydrolase
DUW70_RS09340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DUW70_RS09345	COG0077	Prephenate dehydratase
DUW70_RS09345	COG1605	Chorismate mutase
DUW70_RS09350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DUW70_RS09365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DUW70_RS09375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DUW70_RS09380	COG0583	DNA-binding transcription factor activity
DUW70_RS09435	COG0629	single-stranded DNA binding
DUW70_RS09515	COG0305	Participates in initiation and elongation during chromosome replication
DUW70_RS09750	COG0210	DNA helicase
DUW70_RS09765	COG0604	alcohol dehydrogenase
DUW70_RS09770	COG1733	regulation of RNA biosynthetic process
DUW70_RS09800	COG1136	(ABC) transporter
DUW70_RS09800	COG0577	efflux transmembrane transporter activity
DUW70_RS09830	COG4774	siderophore transport
DUW70_RS09845	COG0784	Response regulator, receiver
DUW70_RS09845	COG4191	Histidine kinase
DUW70_RS09875	COG0446	pyridine nucleotide-disulphide oxidoreductase
DUW70_RS09875	COG1902	pentaerythritol trinitrate reductase activity
DUW70_RS09880	COG0789	Transcriptional regulator
DUW70_RS09885	COG2814	Major facilitator Superfamily
DUW70_RS09895	COG3505	Type IV secretory pathway VirD4
DUW70_RS09905	COG3736	Type IV secretory pathway, component VirB8
DUW70_RS09915	COG2948	multi-organism process
DUW70_RS09935	COG3702	type iv secretory pathway
DUW70_RS10045	COG0456	acetyltransferase
DUW70_RS10050	COG2249	NAD(P)H dehydrogenase (quinone) activity
DUW70_RS10055	COG1733	regulation of RNA biosynthetic process
DUW70_RS10065	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DUW70_RS10075	COG1902	pentaerythritol trinitrate reductase activity
DUW70_RS10080	COG0668	transmembrane transport
DUW70_RS10090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DUW70_RS10110	COG0534	Mate efflux family protein
DUW70_RS10115	COG1073	alpha beta
DUW70_RS10115	COG2226	methyltransferase
DUW70_RS10130	COG3243	poly(R)-hydroxyalkanoic acid synthase
DUW70_RS10140	COG1983	PspC domain protein
DUW70_RS10155	COG2183	response to ionizing radiation
DUW70_RS10160	COG5001	Diguanylate cyclase
DUW70_RS10160	COG5002	protein histidine kinase activity
DUW70_RS10160	COG3447	MASE1 domain protein
DUW70_RS10255	COG0789	Transcriptional regulator
DUW70_RS10265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS10280	COG0531	amino acid
DUW70_RS10310	COG4206	TonB-dependent receptor
DUW70_RS10310	COG1629	transport
DUW70_RS10335	COG0519	Catalyzes the synthesis of GMP from XMP
DUW70_RS10335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DUW70_RS10340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DUW70_RS10355	COG0587	DNA-directed DNA polymerase activity
DUW70_RS10435	COG1285	pathogenesis
DUW70_RS10445	COG2186	Transcriptional regulator
DUW70_RS10450	COG1304	FMN binding
DUW70_RS10455	COG0277	FAD linked oxidase domain protein
DUW70_RS10495	COG3161	chorismate lyase activity
DUW70_RS10510	COG0583	DNA-binding transcription factor activity
DUW70_RS10520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DUW70_RS10530	COG2814	Major facilitator Superfamily
DUW70_RS10535	COG2197	response regulator
DUW70_RS10540	COG3850	Histidine kinase
DUW70_RS10555	COG1335	isochorismatase
DUW70_RS10565	COG1228	amidohydrolase
DUW70_RS10575	COG2814	Major facilitator Superfamily
DUW70_RS10630	COG4964	Belongs to the GSP D family
DUW70_RS10675	COG2226	methyltransferase
DUW70_RS10695	COG4772	TonB-dependent receptor
DUW70_RS10740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DUW70_RS10755	COG4206	TonB-dependent receptor
DUW70_RS10770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DUW70_RS10775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DUW70_RS10790	COG1914	H( )-stimulated, divalent metal cation uptake system
DUW70_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUW70_RS10865	COG2409	Drug exporters of the RND superfamily
DUW70_RS10875	COG1169	isochorismate synthase
DUW70_RS10880	COG1021	2,3-dihydroxybenzoate-AMP ligase
DUW70_RS10885	COG3433	isochorismatase activity
DUW70_RS10885	COG1535	isochorismatase
DUW70_RS10890	COG3433	isochorismatase activity
DUW70_RS10890	COG1535	isochorismatase
DUW70_RS10895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUW70_RS10895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DUW70_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS10905	COG1943	Transposase
DUW70_RS10980	COG0798	PFAM Bile acid sodium symporter
DUW70_RS10985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUW70_RS10995	COG0431	NADPH-dependent FMN reductase
DUW70_RS11000	COG4771	TonB-dependent receptor
DUW70_RS11005	COG0789	Transcriptional regulator
DUW70_RS11055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DUW70_RS11060	COG0315	cyclic pyranopterin monophosphate synthase activity
DUW70_RS11060	COG0521	Mo-molybdopterin cofactor biosynthetic process
DUW70_RS11065	COG0303	'Molybdopterin
DUW70_RS11075	COG0314	molybdopterin synthase activity
DUW70_RS11080	COG0746	molybdenum cofactor guanylyltransferase activity
DUW70_RS11090	COG2223	nitrite transmembrane transporter activity
DUW70_RS11095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DUW70_RS11100	COG1140	nitrate reductase beta subunit
DUW70_RS11105	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DUW70_RS11110	COG2181	nitrate reductase activity
DUW70_RS11115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DUW70_RS11130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUW70_RS11135	COG0725	ABC transporter, periplasmic molybdate-binding protein
DUW70_RS11140	COG4149	molybdate abc transporter
DUW70_RS11145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DUW70_RS11150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DUW70_RS11155	COG0840	transmembrane signaling receptor activity
DUW70_RS11230	COG1459	type II secretion system
DUW70_RS11275	COG0811	peptide transport
DUW70_RS11305	COG1335	isochorismatase
DUW70_RS11310	COG1335	isochorismatase
DUW70_RS11355	COG3920	Histidine kinase
DUW70_RS11355	COG2202	Pas domain
DUW70_RS11375	COG0477	Major facilitator Superfamily
DUW70_RS11390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS11395	COG3537	Alpha-1,2-mannosidase
DUW70_RS11400	COG0642	Histidine kinase
DUW70_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS11430	COG0583	DNA-binding transcription factor activity
DUW70_RS11435	COG5002	protein histidine kinase activity
DUW70_RS11440	COG0745	RESPONSE REGULATOR receiver
DUW70_RS11460	COG4771	TonB-dependent receptor
DUW70_RS11475	COG1136	(ABC) transporter
DUW70_RS11500	COG0477	Major facilitator Superfamily
DUW70_RS11525	COG0243	molybdopterin cofactor binding
DUW70_RS11570	COG4566	intracellular signal transduction
DUW70_RS11575	COG4191	Histidine kinase
DUW70_RS11580	COG1285	pathogenesis
DUW70_RS11585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DUW70_RS11635	COG4774	siderophore transport
DUW70_RS11645	COG3214	Protein conserved in bacteria
DUW70_RS11665	COG4774	siderophore transport
DUW70_RS11685	COG2205	protein histidine kinase activity
DUW70_RS11690	COG0745	RESPONSE REGULATOR receiver
DUW70_RS11700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS11705	COG1136	(ABC) transporter
DUW70_RS11705	COG0577	efflux transmembrane transporter activity
DUW70_RS11710	COG3447	MASE1 domain protein
DUW70_RS11710	COG5001	Diguanylate cyclase
DUW70_RS11710	COG5002	protein histidine kinase activity
DUW70_RS11805	COG2204	response regulator
DUW70_RS11830	COG0583	DNA-binding transcription factor activity
DUW70_RS11850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DUW70_RS11855	COG0583	DNA-binding transcription factor activity
DUW70_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS11900	COG2271	Major facilitator Superfamily
DUW70_RS11920	COG2186	Transcriptional regulator
DUW70_RS11930	COG0318	PFAM AMP-dependent synthetase and ligase
DUW70_RS11940	COG0642	Histidine kinase
DUW70_RS11965	COG2207	Transcriptional regulator
DUW70_RS11990	COG4555	ABC transporter
DUW70_RS12005	COG4206	TonB-dependent receptor
DUW70_RS12010	COG5265	(ABC) transporter
DUW70_RS12035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DUW70_RS12050	COG0583	DNA-binding transcription factor activity
DUW70_RS12055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DUW70_RS12075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DUW70_RS12075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DUW70_RS12080	COG1105	Belongs to the carbohydrate kinase PfkB family
DUW70_RS12085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DUW70_RS12085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DUW70_RS12090	COG1609	Transcriptional regulator
DUW70_RS12100	COG0649	NAD binding
DUW70_RS12175	COG0667	Aldo Keto reductase
DUW70_RS12210	COG1063	alcohol dehydrogenase
DUW70_RS12230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DUW70_RS12240	COG2200	EAL domain
DUW70_RS12270	COG3685	Protein conserved in bacteria
DUW70_RS12300	COG1309	transcriptional regulator
DUW70_RS12310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUW70_RS12315	COG1595	DNA-templated transcription, initiation
DUW70_RS12335	COG0583	DNA-binding transcription factor activity
DUW70_RS12345	COG1764	response to oxidative stress
DUW70_RS12350	COG2080	2 iron, 2 sulfur cluster binding
DUW70_RS12355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DUW70_RS12360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DUW70_RS12365	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DUW70_RS12455	COG0454	-acetyltransferase
DUW70_RS12455	COG0456	acetyltransferase
DUW70_RS12465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DUW70_RS12475	COG4251	negative regulation of phosphorylation
DUW70_RS12480	COG0784	Response regulator, receiver
DUW70_RS12500	COG1595	DNA-templated transcription, initiation
DUW70_RS12515	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DUW70_RS12525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DUW70_RS12555	COG2197	response regulator
DUW70_RS12560	COG5002	protein histidine kinase activity
DUW70_RS12560	COG0784	Response regulator, receiver
DUW70_RS12595	COG3846	protein secretion by the type IV secretion system
DUW70_RS12610	COG3451	type IV secretory pathway VirB4
DUW70_RS12620	COG3838	Conjugal transfer protein Trbc
DUW70_RS12625	COG4962	Type ii secretion system protein e
DUW70_RS12655	COG2076	Multidrug Resistance protein
DUW70_RS12665	COG0583	DNA-binding transcription factor activity
DUW70_RS12700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DUW70_RS12705	COG1127	ABC transporter
DUW70_RS12725	COG4959	Type IV secretory pathway protease TraF
DUW70_RS12770	COG5489	Protein of unknown function (DUF736)
DUW70_RS12780	COG1475	DNA binding
DUW70_RS12795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DUW70_RS12825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DUW70_RS12845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DUW70_RS12855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DUW70_RS12860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUW70_RS12865	COG4558	Periplasmic binding protein
DUW70_RS12875	COG2819	hydrolase of the alpha beta superfamily
DUW70_RS12890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DUW70_RS12910	COG1674	ftsk spoiiie
DUW70_RS12915	COG0492	ferredoxin-NADP+ reductase activity
DUW70_RS12955	COG0542	response to heat
DUW70_RS12965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DUW70_RS12980	COG0482	sulfurtransferase activity
DUW70_RS12985	COG2915	High frequency lysogenization protein hflD homolog
DUW70_RS13030	COG5002	protein histidine kinase activity
DUW70_RS13050	COG0835	chemotaxis
DUW70_RS13050	COG0784	Response regulator, receiver
DUW70_RS13055	COG1815	bacterial-type flagellum-dependent cell motility
DUW70_RS13060	COG1558	bacterial-type flagellum-dependent cell motility
DUW70_RS13075	COG4787	bacterial-type flagellum-dependent cell motility
DUW70_RS13085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DUW70_RS13140	COG2197	response regulator
DUW70_RS13165	COG1677	Flagellar hook-basal body complex protein FliE
DUW70_RS13215	COG3190	flagellar
DUW70_RS13225	COG1987	bacterial-type flagellum assembly
DUW70_RS13240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DUW70_RS13245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DUW70_RS13270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DUW70_RS13275	COG2198	Histidine kinase
DUW70_RS13275	COG0784	Response regulator, receiver
DUW70_RS13275	COG0643	Histidine kinase
DUW70_RS13280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DUW70_RS13285	COG1360	Flagellar Motor Protein
DUW70_RS13295	COG0835	chemotaxis
DUW70_RS13305	COG0745	RESPONSE REGULATOR receiver
DUW70_RS13315	COG0840	transmembrane signaling receptor activity
DUW70_RS13320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DUW70_RS13325	COG0835	chemotaxis
DUW70_RS13335	COG0840	transmembrane signaling receptor activity
DUW70_RS13350	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DUW70_RS13390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DUW70_RS13395	COG1309	transcriptional regulator
DUW70_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
DUW70_RS13405	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DUW70_RS13410	COG0318	PFAM AMP-dependent synthetase and ligase
DUW70_RS13415	COG1024	Enoyl-CoA hydratase
DUW70_RS13420	COG2198	Histidine kinase
DUW70_RS13420	COG0784	Response regulator, receiver
DUW70_RS13420	COG2205	protein histidine kinase activity
DUW70_RS13435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DUW70_RS13445	COG1012	belongs to the aldehyde dehydrogenase family
DUW70_RS13470	COG4676	Protein conserved in bacteria
DUW70_RS13480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DUW70_RS13490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DUW70_RS13495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DUW70_RS13500	COG0505	Belongs to the CarA family
DUW70_RS13505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DUW70_RS13520	COG2249	NAD(P)H dehydrogenase (quinone) activity
DUW70_RS13565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DUW70_RS13585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS13590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS13595	COG0745	RESPONSE REGULATOR receiver
DUW70_RS13600	COG2205	protein histidine kinase activity
DUW70_RS13615	COG0277	FAD linked oxidase domain protein
DUW70_RS13620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DUW70_RS13630	COG0531	amino acid
DUW70_RS13635	COG0531	amino acid
DUW70_RS13645	COG0235	Class ii aldolase
DUW70_RS13650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DUW70_RS13655	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DUW70_RS13675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUW70_RS13685	COG1609	Transcriptional regulator
DUW70_RS13690	COG3537	Alpha-1,2-mannosidase
DUW70_RS13705	COG0789	Transcriptional regulator
DUW70_RS13720	COG3142	Participates in the control of copper homeostasis
DUW70_RS13725	COG1446	asparaginase
DUW70_RS13745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DUW70_RS13745	COG0140	phosphoribosyl-ATP diphosphatase activity
DUW70_RS13750	COG0107	imidazoleglycerol-phosphate synthase activity
DUW70_RS13755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DUW70_RS13760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DUW70_RS13765	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DUW70_RS13765	COG0131	Imidazoleglycerol-phosphate dehydratase
DUW70_RS13770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DUW70_RS13775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DUW70_RS13780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DUW70_RS13795	COG0124	histidyl-tRNA synthetase
DUW70_RS13800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUW70_RS13810	COG0083	homoserine kinase activity
DUW70_RS13815	COG0527	aspartate kinase activity
DUW70_RS13815	COG0460	homoserine dehydrogenase
DUW70_RS13855	COG0640	Transcriptional regulator
DUW70_RS13865	COG5002	protein histidine kinase activity
DUW70_RS13875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DUW70_RS13880	COG4999	Histidine kinase
DUW70_RS13880	COG3437	response regulator, receiver
DUW70_RS13880	COG3850	Histidine kinase
DUW70_RS13880	COG2205	protein histidine kinase activity
DUW70_RS13885	COG4191	Histidine kinase
DUW70_RS13885	COG0784	Response regulator, receiver
DUW70_RS13890	COG0745	RESPONSE REGULATOR receiver
DUW70_RS13920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUW70_RS13960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUW70_RS13985	COG2244	polysaccharide biosynthetic process
DUW70_RS13990	COG0489	protein tyrosine kinase activity
DUW70_RS13990	COG3206	protein involved in exopolysaccharide biosynthesis
DUW70_RS13995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUW70_RS14005	COG1012	belongs to the aldehyde dehydrogenase family
DUW70_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS14025	COG0167	dihydroorotate dehydrogenase activity
DUW70_RS14030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DUW70_RS14035	COG0697	spore germination
DUW70_RS14050	COG1309	transcriptional regulator
DUW70_RS14070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DUW70_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS14090	COG0583	DNA-binding transcription factor activity
DUW70_RS14095	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DUW70_RS14120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUW70_RS14125	COG1126	abc transporter atp-binding protein
DUW70_RS14135	COG1473	amidohydrolase
DUW70_RS14140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUW70_RS14145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUW70_RS14155	COG0431	NADPH-dependent FMN reductase
DUW70_RS14175	COG4716	Myosin-crossreactive antigen
DUW70_RS14190	COG0640	Transcriptional regulator
DUW70_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS14220	COG1073	alpha beta
DUW70_RS14240	COG0583	DNA-binding transcription factor activity
DUW70_RS14315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DUW70_RS14365	COG0789	Transcriptional regulator
DUW70_RS14445	COG0582	viral genome integration into host DNA
DUW70_RS14450	COG0519	Catalyzes the synthesis of GMP from XMP
DUW70_RS14450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DUW70_RS14470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DUW70_RS14470	COG0475	glutathione-regulated potassium exporter activity
DUW70_RS14475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DUW70_RS14500	COG1160	GTP binding
DUW70_RS14505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUW70_RS14510	COG2976	Protein conserved in bacteria
DUW70_RS14525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DUW70_RS14530	COG0105	UTP biosynthetic process
DUW70_RS14540	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUW70_RS14540	COG1024	Enoyl-CoA hydratase
DUW70_RS14545	COG0183	Belongs to the thiolase family
DUW70_RS14555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DUW70_RS14570	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DUW70_RS14580	COG0776	regulation of translation
DUW70_RS14590	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DUW70_RS14595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DUW70_RS14605	COG2957	Belongs to the agmatine deiminase family
DUW70_RS14610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUW70_RS14625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS14650	COG0488	(ABC) transporter
DUW70_RS14655	COG0583	DNA-binding transcription factor activity
DUW70_RS14665	COG0513	Belongs to the DEAD box helicase family
DUW70_RS14670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DUW70_RS14675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DUW70_RS14680	COG0625	glutathione transferase activity
DUW70_RS14695	COG0564	pseudouridine synthase activity
DUW70_RS14700	COG4681	YaeQ
DUW70_RS14705	COG2081	HI0933 family
DUW70_RS14715	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DUW70_RS14720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DUW70_RS14730	COG1862	Preprotein translocase
DUW70_RS14735	COG0343	queuine tRNA-ribosyltransferase activity
DUW70_RS14740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DUW70_RS14745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DUW70_RS14775	COG1132	(ABC) transporter
DUW70_RS14785	COG1605	Chorismate mutase
DUW70_RS14785	COG0287	Prephenate dehydrogenase
DUW70_RS14790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DUW70_RS14800	COG2223	nitrite transmembrane transporter activity
DUW70_RS14805	COG2207	Transcriptional regulator
DUW70_RS14810	COG0484	heat shock protein binding
DUW70_RS14815	COG0443	Heat shock 70 kDa protein
DUW70_RS14820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DUW70_RS14825	COG1420	regulation of RNA biosynthetic process
DUW70_RS14830	COG0497	DNA recombination
DUW70_RS14835	COG0583	DNA-binding transcription factor activity
DUW70_RS14845	COG0735	belongs to the Fur family
DUW70_RS14850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUW70_RS14855	COG2914	Belongs to the UPF0125 (RnfH) family
DUW70_RS14865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DUW70_RS15195	COG2974	May be involved in recombination
DUW70_RS15275	COG1404	Belongs to the peptidase S8 family
DUW70_RS15375	COG0583	DNA-binding transcription factor activity
DUW70_RS15380	COG2885	chlorophyll binding
DUW70_RS15385	COG0415	Belongs to the DNA photolyase family
DUW70_RS15390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DUW70_RS15410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DUW70_RS15420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUW70_RS15425	COG0405	Gamma-glutamyltransferase
DUW70_RS15430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DUW70_RS15440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DUW70_RS15445	COG0742	ribosomal rna small subunit methyltransferase
DUW70_RS15470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DUW70_RS15485	COG4591	ABC-type transport system involved in lipoprotein release permease component
DUW70_RS15505	COG1053	succinate dehydrogenase
DUW70_RS15510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DUW70_RS15515	COG2009	succinate dehydrogenase
DUW70_RS15540	COG0837	glucose binding
DUW70_RS15550	COG0129	dihydroxy-acid dehydratase activity
DUW70_RS15555	COG0800	Aldolase
DUW70_RS15565	COG0671	phosphoesterase, PA-phosphatase related
DUW70_RS15570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DUW70_RS15580	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DUW70_RS15595	COG0166	Belongs to the GPI family
DUW70_RS15600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DUW70_RS15610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DUW70_RS15615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DUW70_RS15620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DUW70_RS15625	COG0617	tRNA 3'-terminal CCA addition
DUW70_RS15635	COG0477	Major facilitator Superfamily
DUW70_RS15640	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DUW70_RS15650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUW70_RS15660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DUW70_RS15665	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DUW70_RS15680	COG0351	phosphomethylpyrimidine kinase
DUW70_RS15680	COG0352	thiamine-phosphate diphosphorylase activity
DUW70_RS15705	COG0583	DNA-binding transcription factor activity
DUW70_RS15710	COG1741	Belongs to the pirin family
DUW70_RS15725	COG2223	nitrite transmembrane transporter activity
DUW70_RS15740	COG3258	Cytochrome c
DUW70_RS15760	COG3540	Alkaline phosphatase
DUW70_RS15795	COG4773	Receptor
DUW70_RS15820	COG1122	ATPase activity
DUW70_RS15835	COG0577	efflux transmembrane transporter activity
DUW70_RS15835	COG1136	(ABC) transporter
DUW70_RS15840	COG1136	(ABC) transporter
DUW70_RS15870	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DUW70_RS15875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DUW70_RS15880	COG2137	regulation of response to DNA damage stimulus
DUW70_RS15885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DUW70_RS15890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DUW70_RS15895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DUW70_RS15900	COG1546	Belongs to the CinA family
DUW70_RS15905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DUW70_RS15910	COG1923	regulation of RNA biosynthetic process
DUW70_RS15915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DUW70_RS15920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DUW70_RS15930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DUW70_RS15935	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DUW70_RS15940	COG1534	Rna-binding protein
DUW70_RS15965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DUW70_RS15970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DUW70_RS15975	COG2840	Smr protein MutS2
DUW70_RS15985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DUW70_RS15990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DUW70_RS15995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DUW70_RS16000	COG0148	phosphopyruvate hydratase activity
DUW70_RS16015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DUW70_RS16020	COG0504	CTP synthase activity
DUW70_RS16035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUW70_RS16055	COG1253	flavin adenine dinucleotide binding
DUW70_RS16070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUW70_RS16075	COG1054	Belongs to the UPF0176 family
DUW70_RS16090	COG0644	oxidoreductase
DUW70_RS16105	COG0069	glutamate synthase activity
DUW70_RS16110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DUW70_RS16125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DUW70_RS16140	COG0348	domain, Protein
DUW70_RS16160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUW70_RS16165	COG4977	sequence-specific DNA binding
DUW70_RS16165	COG1917	Cupin 2, conserved barrel domain protein
DUW70_RS16200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DUW70_RS16205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUW70_RS16205	COG0456	acetyltransferase
DUW70_RS16250	COG0577	efflux transmembrane transporter activity
DUW70_RS16250	COG1136	(ABC) transporter
DUW70_RS16315	COG0629	single-stranded DNA binding
DUW70_RS16420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DUW70_RS16640	COG2003	Belongs to the UPF0758 family
DUW70_RS16690	COG0640	Transcriptional regulator
DUW70_RS16735	COG1595	DNA-templated transcription, initiation
DUW70_RS16745	COG3039	Transposase
DUW70_RS16785	COG3220	belongs to the UPF0276 family
DUW70_RS16815	COG0785	Cytochrome C biogenesis protein
DUW70_RS16820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS16825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DUW70_RS16835	COG0659	secondary active sulfate transmembrane transporter activity
DUW70_RS16840	COG0589	response to stress
DUW70_RS16845	COG0583	DNA-binding transcription factor activity
DUW70_RS16850	COG1396	sequence-specific DNA binding
DUW70_RS16860	COG0582	viral genome integration into host DNA
DUW70_RS16875	COG0322	excinuclease ABC activity
DUW70_RS16885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUW70_RS16890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DUW70_RS16895	COG1663	tetraacyldisaccharide 4'-kinase activity
DUW70_RS16910	COG0811	peptide transport
DUW70_RS16915	COG0658	competence protein
DUW70_RS16915	COG2333	competence protein COMEC
DUW70_RS16930	COG3713	MltA-interacting MipA family protein
DUW70_RS16960	COG0556	nucleotide-excision repair
DUW70_RS17005	COG1611	Belongs to the LOG family
DUW70_RS17025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DUW70_RS17035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUW70_RS17070	COG2969	positive regulation of protein catabolic process
DUW70_RS17075	COG0625	glutathione transferase activity
DUW70_RS17080	COG2857	Cytochrome c1
DUW70_RS17085	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DUW70_RS17090	COG0723	plastoquinol--plastocyanin reductase activity
DUW70_RS17095	COG0741	lytic transglycosylase activity
DUW70_RS17110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DUW70_RS17115	COG0842	Transport permease protein
DUW70_RS17120	COG1131	(ABC) transporter
DUW70_RS17125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS17130	COG1702	phosphate starvation-inducible protein PhoH
DUW70_RS17135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DUW70_RS17150	COG4535	Mg2 and Co2 transporter CorC
DUW70_RS17165	COG1012	belongs to the aldehyde dehydrogenase family
DUW70_RS17170	COG1177	transmembrane transport
DUW70_RS17175	COG1176	ABC-type spermidine putrescine transport system, permease component I
DUW70_RS17180	COG3842	ATPase activity
DUW70_RS17195	COG0174	glutamine synthetase
DUW70_RS17230	COG2703	oxygen carrier activity
DUW70_RS17235	COG0477	Major facilitator Superfamily
DUW70_RS17250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUW70_RS17260	COG2733	membrane
DUW70_RS17425	COG5566	PFAM Mor transcription activator
DUW70_RS17440	COG0741	lytic transglycosylase activity
DUW70_RS17440	COG0739	heme binding
DUW70_RS17440	COG1196	nuclear chromosome segregation
DUW70_RS17470	COG4373	Mu-like prophage FluMu protein gp28
DUW70_RS17475	COG4383	Mu-like prophage protein gp29
DUW70_RS17505	COG4397	Mu-like prophage major head subunit gpT
DUW70_RS17590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DUW70_RS17590	COG0116	Belongs to the methyltransferase superfamily
DUW70_RS17610	COG0494	nUDIX hydrolase
DUW70_RS17620	COG1024	Enoyl-CoA hydratase
DUW70_RS17630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DUW70_RS17640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DUW70_RS17645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DUW70_RS17655	COG0581	inorganic phosphate transmembrane transporter activity
DUW70_RS17665	COG0704	Plays a role in the regulation of phosphate uptake
DUW70_RS17675	COG3220	belongs to the UPF0276 family
DUW70_RS17685	COG2259	Doxx family
DUW70_RS17690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DUW70_RS17700	COG2205	protein histidine kinase activity
DUW70_RS17710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS17715	COG0577	efflux transmembrane transporter activity
DUW70_RS17715	COG1136	(ABC) transporter
DUW70_RS17720	COG1538	Outer membrane efflux protein
DUW70_RS17725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DUW70_RS17735	COG0557	exoribonuclease II activity
DUW70_RS17745	COG0662	Cupin 2, conserved barrel domain protein
DUW70_RS17755	COG1396	sequence-specific DNA binding
DUW70_RS17775	COG0583	DNA-binding transcription factor activity
DUW70_RS17785	COG2814	Major facilitator Superfamily
DUW70_RS17790	COG1566	PFAM secretion protein HlyD family protein
DUW70_RS17825	COG0475	glutathione-regulated potassium exporter activity
DUW70_RS17830	COG0367	asparagine synthase
DUW70_RS17840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUW70_RS17845	COG1393	Belongs to the ArsC family
DUW70_RS17860	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DUW70_RS17880	COG3188	usher protein
DUW70_RS17900	COG0052	Belongs to the universal ribosomal protein uS2 family
DUW70_RS17905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DUW70_RS17915	COG0528	UMP kinase activity
DUW70_RS17920	COG0233	cytoplasmic translational termination
DUW70_RS17925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DUW70_RS17930	COG0575	Belongs to the CDS family
DUW70_RS17935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DUW70_RS17940	COG0750	zinc metalloprotease
DUW70_RS17945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUW70_RS17955	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DUW70_RS17965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DUW70_RS17990	COG0825	malonyl-CoA metabolic process
DUW70_RS17995	COG1981	membrane
DUW70_RS18015	COG1695	Transcriptional regulator
DUW70_RS18060	COG1132	(ABC) transporter
DUW70_RS18085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DUW70_RS18095	COG1187	pseudouridine synthase activity
DUW70_RS18105	COG5002	protein histidine kinase activity
DUW70_RS18105	COG5001	Diguanylate cyclase
DUW70_RS18150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DUW70_RS18195	COG0735	belongs to the Fur family
DUW70_RS18200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DUW70_RS18215	COG4452	Inner membrane protein CreD
DUW70_RS18220	COG2205	protein histidine kinase activity
DUW70_RS18225	COG0745	RESPONSE REGULATOR receiver
DUW70_RS18230	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DUW70_RS18240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DUW70_RS18250	COG3590	peptidase
DUW70_RS18265	COG0583	DNA-binding transcription factor activity
DUW70_RS18280	COG0509	glycine decarboxylation via glycine cleavage system
DUW70_RS18285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DUW70_RS18295	COG0330	HflC and HflK could
DUW70_RS18305	COG1742	UPF0060 membrane protein
DUW70_RS18310	COG3956	TIGRFAM MazG family protein
DUW70_RS18315	COG1218	3'(2'),5'-bisphosphate nucleotidase
DUW70_RS18320	COG0494	nUDIX hydrolase
DUW70_RS18330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DUW70_RS18345	COG2198	Histidine kinase
DUW70_RS18345	COG0784	Response regulator, receiver
DUW70_RS18345	COG0643	Histidine kinase
DUW70_RS18350	COG0840	transmembrane signaling receptor activity
DUW70_RS18355	COG0835	chemotaxis
DUW70_RS18370	COG0189	ligase activity
DUW70_RS18385	COG1199	ATP-dependent helicase activity
DUW70_RS18400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUW70_RS18405	COG1216	Glycosyl transferase, family 2
DUW70_RS18415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DUW70_RS18425	COG1643	Atp-dependent helicase
DUW70_RS18430	COG0783	Belongs to the Dps family
DUW70_RS18435	COG0514	ATP-dependent DNA helicase (RecQ)
DUW70_RS18480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DUW70_RS18810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DUW70_RS18815	COG0602	queuosine metabolic process
DUW70_RS18825	COG2885	chlorophyll binding
DUW70_RS18830	COG0823	Involved in the tonB-independent uptake of proteins
DUW70_RS18845	COG0811	peptide transport
DUW70_RS18850	COG0824	Thioesterase
DUW70_RS18855	COG2255	four-way junction helicase activity
DUW70_RS18865	COG0632	four-way junction helicase activity
DUW70_RS18870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DUW70_RS18875	COG0217	transcriptional regulatory protein
DUW70_RS18895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DUW70_RS18930	COG0488	(ABC) transporter
DUW70_RS18940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DUW70_RS18940	COG4651	solute:proton antiporter activity
DUW70_RS18950	COG0745	RESPONSE REGULATOR receiver
DUW70_RS18955	COG2205	protein histidine kinase activity
DUW70_RS18965	COG0542	response to heat
DUW70_RS18990	COG0028	Belongs to the TPP enzyme family
DUW70_RS19015	COG3387	PFAM Glycoside hydrolase 15-related
DUW70_RS19020	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DUW70_RS19025	COG3011	Protein conserved in bacteria
DUW70_RS19040	COG0564	pseudouridine synthase activity
DUW70_RS19045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUW70_RS19055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DUW70_RS19055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUW70_RS19065	COG0045	succinate-CoA ligase (ADP-forming) activity
DUW70_RS19100	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DUW70_RS19110	COG2205	protein histidine kinase activity
DUW70_RS19115	COG0745	RESPONSE REGULATOR receiver
DUW70_RS19130	COG0189	ligase activity
DUW70_RS19155	COG3152	Membrane
DUW70_RS19175	COG2022	thiamine diphosphate biosynthetic process
DUW70_RS19180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DUW70_RS19185	COG0471	metal ion transport
DUW70_RS19185	COG3273	potassium ion transport
DUW70_RS19205	COG1970	mechanosensitive ion channel activity
DUW70_RS19215	COG1115	amino acid carrier protein
DUW70_RS19225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DUW70_RS19230	COG1115	amino acid carrier protein
DUW70_RS19235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUW70_RS19240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS19245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS19270	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DUW70_RS19280	COG3588	fructose-bisphosphate aldolase
DUW70_RS19285	COG0469	pyruvate kinase activity
DUW70_RS19295	COG0126	phosphoglycerate kinase activity
DUW70_RS19330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DUW70_RS19335	COG3047	cAMP biosynthetic process
DUW70_RS19375	COG3093	addiction module antidote protein HigA
DUW70_RS19385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DUW70_RS19390	COG1301	dicarboxylic acid transport
DUW70_RS19400	COG2304	oxidoreductase activity
DUW70_RS19420	COG0714	Associated with various cellular activities
DUW70_RS19450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DUW70_RS19465	COG5295	Hep Hag repeat protein
DUW70_RS19505	COG0254	rRNA binding
DUW70_RS19520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DUW70_RS19530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DUW70_RS19535	COG1758	RNA polymerase activity
DUW70_RS19550	COG0437	4 iron, 4 sulfur cluster binding
DUW70_RS19555	COG2864	formate dehydrogenase
DUW70_RS19565	COG1921	L-seryl-tRNASec selenium transferase activity
DUW70_RS19570	COG3276	selenocysteine insertion sequence binding
DUW70_RS19580	COG0709	Synthesizes selenophosphate from selenide and ATP
DUW70_RS19595	COG1561	YicC-like family, N-terminal region
DUW70_RS19600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DUW70_RS19605	COG0346	lactoylglutathione lyase activity
DUW70_RS19615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DUW70_RS19630	COG0006	proline dipeptidase activity
DUW70_RS19640	COG0006	proline dipeptidase activity
DUW70_RS19645	COG3079	Belongs to the UPF0149 family
DUW70_RS19665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DUW70_RS19675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DUW70_RS19685	COG2912	Transglutaminase-like superfamily
DUW70_RS19690	COG1773	rubredoxin
DUW70_RS19700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DUW70_RS19715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUW70_RS19720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUW70_RS19735	COG4221	oxidoreductase activity
DUW70_RS19760	COG0671	phosphoesterase, PA-phosphatase related
DUW70_RS19770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DUW70_RS19775	COG0563	adenylate kinase activity
DUW70_RS19800	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DUW70_RS19810	COG0848	biopolymer transport protein
DUW70_RS19820	COG2832	Protein of unknown function (DUF454)
DUW70_RS19855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DUW70_RS19880	COG0745	RESPONSE REGULATOR receiver
DUW70_RS19890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DUW70_RS19895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DUW70_RS19905	COG0405	Gamma-glutamyltransferase
DUW70_RS19910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DUW70_RS19930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DUW70_RS19935	COG2226	methyltransferase
DUW70_RS19950	COG0473	3-isopropylmalate dehydrogenase activity
DUW70_RS19975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS19980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS19995	COG1538	Outer membrane efflux protein
DUW70_RS20000	COG0531	amino acid
DUW70_RS20005	COG1519	Transferase
DUW70_RS20010	COG1560	Kdo2-lipid A biosynthetic process
DUW70_RS20060	COG1301	dicarboxylic acid transport
DUW70_RS20070	COG4191	Histidine kinase
DUW70_RS20085	COG0642	Histidine kinase
DUW70_RS20100	COG2851	Citrate transporter
DUW70_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS20130	COG1162	GTPase activity
DUW70_RS20135	COG0436	Aminotransferase
DUW70_RS20155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DUW70_RS20170	COG1228	amidohydrolase
DUW70_RS20175	COG0804	urea catabolic process
DUW70_RS20185	COG1307	EDD domain protein, DegV family
DUW70_RS20225	COG4251	negative regulation of phosphorylation
DUW70_RS20225	COG3706	GGDEF domain
DUW70_RS20225	COG2203	Gaf domain
DUW70_RS20225	COG5001	Diguanylate cyclase
DUW70_RS20230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DUW70_RS20240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DUW70_RS20250	COG4206	TonB-dependent receptor
DUW70_RS20260	COG1902	pentaerythritol trinitrate reductase activity
DUW70_RS20285	COG0583	DNA-binding transcription factor activity
DUW70_RS20290	COG1064	alcohol dehydrogenase
DUW70_RS20300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DUW70_RS20320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DUW70_RS20325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DUW70_RS20335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DUW70_RS20340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DUW70_RS20355	COG1522	sequence-specific DNA binding
DUW70_RS20365	COG4773	Receptor
DUW70_RS20370	COG4206	TonB-dependent receptor
DUW70_RS20395	COG0617	tRNA 3'-terminal CCA addition
DUW70_RS20425	COG3468	outer membrane autotransporter barrel domain protein
DUW70_RS20435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DUW70_RS20440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DUW70_RS20445	COG1609	Transcriptional regulator
DUW70_RS20455	COG0837	glucose binding
DUW70_RS20465	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DUW70_RS20485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DUW70_RS20495	COG4191	Histidine kinase
DUW70_RS20500	COG0784	Response regulator, receiver
DUW70_RS20505	COG4251	negative regulation of phosphorylation
DUW70_RS20510	COG2823	Periplasmic or secreted lipoprotein
DUW70_RS20515	COG0673	inositol 2-dehydrogenase activity
DUW70_RS20520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DUW70_RS20540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DUW70_RS20545	COG0321	lipoyl(octanoyl) transferase activity
DUW70_RS20550	COG2921	Belongs to the UPF0250 family
DUW70_RS20560	COG1686	Belongs to the peptidase S11 family
DUW70_RS20565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DUW70_RS20570	COG2951	lytic endotransglycosylase activity
DUW70_RS20585	COG0772	Belongs to the SEDS family
DUW70_RS20590	COG0772	Belongs to the SEDS family
DUW70_RS20595	COG0768	penicillin binding
DUW70_RS20605	COG1792	Involved in formation and maintenance of cell shape
DUW70_RS20610	COG1077	Cell shape determining protein MreB Mrl
DUW70_RS20615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUW70_RS20630	COG0308	aminopeptidase N
DUW70_RS20635	COG2226	methyltransferase
DUW70_RS20665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS20680	COG0673	inositol 2-dehydrogenase activity
DUW70_RS20690	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DUW70_RS20710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DUW70_RS20720	COG2832	Protein of unknown function (DUF454)
DUW70_RS20730	COG0436	Aminotransferase
DUW70_RS20735	COG1505	serine-type exopeptidase activity
DUW70_RS20760	COG0697	spore germination
DUW70_RS20770	COG1666	GTP binding
DUW70_RS20800	COG0339	signal peptide processing
DUW70_RS20810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DUW70_RS20830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DUW70_RS20840	COG1136	(ABC) transporter
DUW70_RS20845	COG0577	efflux transmembrane transporter activity
DUW70_RS20845	COG1136	(ABC) transporter
DUW70_RS20850	COG0577	efflux transmembrane transporter activity
DUW70_RS20860	COG2204	response regulator
DUW70_RS20865	COG4191	Histidine kinase
DUW70_RS20875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DUW70_RS20890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DUW70_RS20895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DUW70_RS20900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DUW70_RS20905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DUW70_RS20910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DUW70_RS20915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DUW70_RS20925	COG0356	it plays a direct role in the translocation of protons across the membrane
DUW70_RS20940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DUW70_RS20945	COG0508	dehydrogenase complex catalyzes the overall conversion of
DUW70_RS20965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DUW70_RS20990	COG0181	hydroxymethylbilane synthase activity
DUW70_RS21000	COG2972	Histidine kinase
DUW70_RS21000	COG0745	RESPONSE REGULATOR receiver
DUW70_RS21015	COG4771	TonB-dependent receptor
DUW70_RS21030	COG0840	transmembrane signaling receptor activity
DUW70_RS21070	COG0477	Major facilitator Superfamily
DUW70_RS21095	COG0583	DNA-binding transcription factor activity
DUW70_RS21100	COG0477	Major facilitator Superfamily
DUW70_RS21135	COG0625	glutathione transferase activity
DUW70_RS21150	COG2259	Doxx family
DUW70_RS21170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DUW70_RS21185	COG4983	Phage plasmid primase, P4 family domain protein
DUW70_RS21230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUW70_RS21240	COG0582	viral genome integration into host DNA
DUW70_RS21250	COG3550	peptidyl-serine autophosphorylation
DUW70_RS21255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DUW70_RS21260	COG1490	D-aminoacyl-tRNA deacylase activity
DUW70_RS21305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DUW70_RS21305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DUW70_RS21310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DUW70_RS21315	COG0242	peptide deformylase activity
DUW70_RS21325	COG0758	DNA mediated transformation
DUW70_RS21330	COG2922	Belongs to the Smg family
DUW70_RS21340	COG1714	RDD family
DUW70_RS21345	COG1754	DNA topoisomerase type I activity
DUW70_RS21345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DUW70_RS21350	COG0009	L-threonylcarbamoyladenylate synthase
DUW70_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS21375	COG0616	signal peptide processing
DUW70_RS21380	COG0534	Mate efflux family protein
DUW70_RS21395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DUW70_RS21400	COG0625	glutathione transferase activity
DUW70_RS21410	COG1252	NADH dehydrogenase
DUW70_RS21430	COG2860	membrane
DUW70_RS21440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS21445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS21455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DUW70_RS21475	COG1846	Transcriptional regulator
DUW70_RS21485	COG0625	glutathione transferase activity
DUW70_RS21500	COG0459	protein refolding
DUW70_RS21505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DUW70_RS21510	COG2356	endonuclease I
DUW70_RS21515	COG1324	tolerance protein
DUW70_RS21525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUW70_RS21535	COG0840	transmembrane signaling receptor activity
DUW70_RS21555	COG4585	Histidine kinase
DUW70_RS21575	COG0583	DNA-binding transcription factor activity
DUW70_RS21585	COG1785	Belongs to the alkaline phosphatase family
DUW70_RS21590	COG1686	Belongs to the peptidase S11 family
DUW70_RS21600	COG2249	NAD(P)H dehydrogenase (quinone) activity
DUW70_RS21630	COG0511	ligase activity, forming carbon-carbon bonds
DUW70_RS21635	COG0439	Biotin carboxylase
DUW70_RS21650	COG2264	protein methyltransferase activity
DUW70_RS21660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DUW70_RS21665	COG4589	Belongs to the CDS family
DUW70_RS21670	COG0204	Acyl-transferase
DUW70_RS21680	COG0671	phosphoesterase, PA-phosphatase related
DUW70_RS21680	COG2453	phosphatase
DUW70_RS21685	COG2267	carboxylic ester hydrolase activity
DUW70_RS21690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DUW70_RS21695	COG0138	bifunctional purine biosynthesis protein purh
DUW70_RS21705	COG0151	Belongs to the GarS family
DUW70_RS21735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DUW70_RS21740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DUW70_RS21745	COG2201	protein-glutamate methylesterase activity
DUW70_RS21750	COG2177	Part of the ABC transporter FtsEX involved in
DUW70_RS21755	COG2884	Cell division ATP-binding protein ftsE
DUW70_RS21765	COG3118	belongs to the thioredoxin family
DUW70_RS21770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DUW70_RS21775	COG3706	GGDEF domain
DUW70_RS21785	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DUW70_RS21820	COG3209	COG3209 Rhs family protein
DUW70_RS21830	COG1652	LysM domain
DUW70_RS21835	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DUW70_RS21835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DUW70_RS21845	COG1473	amidohydrolase
DUW70_RS21850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DUW70_RS21855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUW70_RS21870	COG1289	transmembrane transporter activity
DUW70_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS21880	COG2814	Major facilitator Superfamily
DUW70_RS21910	COG0316	Belongs to the HesB IscA family
DUW70_RS21950	COG1051	belongs to the nudix hydrolase family
DUW70_RS21965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DUW70_RS21970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DUW70_RS21975	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DUW70_RS21985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DUW70_RS21990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUW70_RS21995	COG0730	response to heat
DUW70_RS22005	COG0134	indole-3-glycerol-phosphate synthase activity
DUW70_RS22010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DUW70_RS22040	COG1597	lipid kinase activity
DUW70_RS22055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DUW70_RS22060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DUW70_RS22070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DUW70_RS22070	COG2111	Na H antiporter
DUW70_RS22075	COG1006	Multisubunit Na H antiporter MnhC subunit
DUW70_RS22080	COG0651	ATP synthesis coupled electron transport
DUW70_RS22085	COG1863	multisubunit Na H antiporter MnhE subunit
DUW70_RS22090	COG2212	antiporter activity
DUW70_RS22095	COG1320	monovalent cation:proton antiporter activity
DUW70_RS22100	COG0530	calcium, potassium:sodium antiporter activity
DUW70_RS22125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DUW70_RS22140	COG4804	nuclease activity
DUW70_RS22155	COG3104	oligopeptide transport
DUW70_RS22160	COG3483	tryptophan 2,3-dioxygenase activity
DUW70_RS22195	COG2378	regulation of single-species biofilm formation
DUW70_RS22210	COG2354	Protein conserved in bacteria
DUW70_RS22215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DUW70_RS22230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DUW70_RS22230	COG3264	Mechanosensitive ion channel
DUW70_RS22245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DUW70_RS22280	COG1166	arginine decarboxylase activity
DUW70_RS22285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DUW70_RS22305	COG2960	long-chain fatty acid transporting porin activity
DUW70_RS22375	COG0606	chelatase, subunit chli
DUW70_RS22390	COG0561	phosphatase activity
DUW70_RS22395	COG3932	Exopolysaccharide synthesis, ExoD
DUW70_RS22420	COG1999	signal sequence binding
DUW70_RS22425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DUW70_RS22430	COG1845	cytochrome c oxidase, subunit III
DUW70_RS22440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DUW70_RS22445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUW70_RS22460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUW70_RS22465	COG1104	cysteine desulfurase activity
DUW70_RS22510	COG2031	fatty acid transporter
DUW70_RS22530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUW70_RS22540	COG0673	inositol 2-dehydrogenase activity
DUW70_RS22550	COG1501	Belongs to the glycosyl hydrolase 31 family
DUW70_RS22555	COG2222	sugar isomerase
DUW70_RS22560	COG1940	carbohydrate kinase activity
DUW70_RS22570	COG1349	DNA-binding transcription factor activity
DUW70_RS22575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DUW70_RS22580	COG2814	Major facilitator Superfamily
DUW70_RS22595	COG1040	competence protein
DUW70_RS22620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DUW70_RS22625	COG0156	8-amino-7-oxononanoate synthase activity
DUW70_RS22630	COG2267	carboxylic ester hydrolase activity
DUW70_RS22635	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS22650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DUW70_RS22665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DUW70_RS22690	COG0714	Associated with various cellular activities
DUW70_RS22700	COG0754	glutathionylspermidine amidase activity
DUW70_RS22710	COG0129	dihydroxy-acid dehydratase activity
DUW70_RS22720	COG1199	ATP-dependent helicase activity
DUW70_RS22730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DUW70_RS22750	COG3781	membrane
DUW70_RS22780	COG0625	glutathione transferase activity
DUW70_RS22800	COG2207	Transcriptional regulator
DUW70_RS22815	COG4555	ABC transporter
DUW70_RS22845	COG0633	Ferredoxin
DUW70_RS22845	COG0543	2 iron, 2 sulfur cluster binding
DUW70_RS22850	COG1131	(ABC) transporter
DUW70_RS22855	COG0842	Transport permease protein
DUW70_RS22865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DUW70_RS22875	COG0084	hydrolase, TatD family'
DUW70_RS22880	COG1643	Atp-dependent helicase
DUW70_RS22890	COG1187	pseudouridine synthase activity
DUW70_RS22905	COG0667	Aldo Keto reductase
DUW70_RS22925	COG1690	Belongs to the RtcB family
DUW70_RS22940	COG0840	transmembrane signaling receptor activity
DUW70_RS22945	COG0583	DNA-binding transcription factor activity
DUW70_RS22950	COG2814	Major facilitator Superfamily
DUW70_RS22955	COG0656	L-ascorbic acid biosynthetic process
DUW70_RS22960	COG2205	protein histidine kinase activity
DUW70_RS22960	COG2198	Histidine kinase
DUW70_RS22960	COG0784	Response regulator, receiver
DUW70_RS22975	COG2267	carboxylic ester hydrolase activity
DUW70_RS22980	COG0393	Putative heavy-metal-binding
DUW70_RS22990	COG1042	CoA-binding domain protein
DUW70_RS22990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUW70_RS22990	COG0045	succinate-CoA ligase (ADP-forming) activity
DUW70_RS22995	COG2239	Acts as a magnesium transporter
DUW70_RS23010	COG3100	YcgL domain-containing protein
DUW70_RS23020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUW70_RS23025	COG1028	Short-chain dehydrogenase reductase Sdr
DUW70_RS23065	COG2986	histidine ammonia-lyase
DUW70_RS23075	COG0463	Glycosyl transferase, family 2
DUW70_RS23080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DUW70_RS23090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUW70_RS23095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUW70_RS23110	COG1294	oxidase, subunit
DUW70_RS23115	COG1271	oxidase subunit
DUW70_RS23125	COG1595	DNA-templated transcription, initiation
DUW70_RS23145	COG0494	nUDIX hydrolase
DUW70_RS23165	COG0408	coproporphyrinogen oxidase activity
DUW70_RS23170	COG2323	membrane
DUW70_RS23185	COG0589	response to stress
DUW70_RS23215	COG0210	DNA helicase
DUW70_RS23230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DUW70_RS23235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DUW70_RS23240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DUW70_RS23245	COG1819	glycosyl
DUW70_RS23260	COG0251	oxidation-reduction process
DUW70_RS23295	COG0463	Glycosyl transferase, family 2
DUW70_RS23310	COG1475	DNA binding
DUW70_RS23315	COG1192	Involved in chromosome partitioning
DUW70_RS23320	COG0357	Ribosomal RNA small subunit methyltransferase G
DUW70_RS23325	COG2091	lysine biosynthetic process via aminoadipic acid
DUW70_RS23380	COG1971	Probably functions as a manganese efflux pump
DUW70_RS23385	COG0784	Response regulator, receiver
DUW70_RS23385	COG2205	protein histidine kinase activity
DUW70_RS23395	COG2911	Protein conserved in bacteria
DUW70_RS23400	COG0729	surface antigen
DUW70_RS23410	COG0752	glycyl-tRNA synthetase alpha subunit
DUW70_RS23415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DUW70_RS23420	COG0519	Catalyzes the synthesis of GMP from XMP
DUW70_RS23420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DUW70_RS23430	COG0805	protein transport
DUW70_RS23440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DUW70_RS23450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DUW70_RS23460	COG0840	transmembrane signaling receptor activity
DUW70_RS23515	COG3135	benzoate transporter
DUW70_RS23530	COG2951	lytic endotransglycosylase activity
DUW70_RS23535	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DUW70_RS23540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DUW70_RS23545	COG3706	GGDEF domain
DUW70_RS23575	COG0302	gtp cyclohydrolase
DUW70_RS23590	COG1566	PFAM secretion protein HlyD family protein
DUW70_RS23600	COG1289	transmembrane transporter activity
DUW70_RS23620	COG1074	ATP-dependent DNA helicase activity
DUW70_RS23625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DUW70_RS23630	COG1127	ABC transporter
DUW70_RS23635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DUW70_RS23640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DUW70_RS23655	COG2853	Lipoprotein
DUW70_RS23660	COG0386	Belongs to the glutathione peroxidase family
DUW70_RS23670	COG1322	Protein conserved in bacteria
DUW70_RS23680	COG0604	alcohol dehydrogenase
DUW70_RS23685	COG0583	DNA-binding transcription factor activity
DUW70_RS23705	COG0531	amino acid
DUW70_RS23720	COG2378	regulation of single-species biofilm formation
DUW70_RS23725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DUW70_RS23730	COG0861	Integral membrane protein TerC family
DUW70_RS23740	COG0584	glycerophosphoryl diester phosphodiesterase
DUW70_RS23760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DUW70_RS23775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DUW70_RS23795	COG0582	viral genome integration into host DNA
DUW70_RS23810	COG0706	membrane insertase activity
DUW70_RS23815	COG0594	ribonuclease P activity
DUW70_RS23820	COG0230	Belongs to the bacterial ribosomal protein bL34 family