locus-tag	class	description
BCV67_RS00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV67_RS00050	COG2132	Multicopper oxidase
BCV67_RS00110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS00115	COG0789	Transcriptional regulator
BCV67_RS00130	COG2217	Heavy metal translocating P-type atpase
BCV67_RS00140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BCV67_RS00145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCV67_RS00160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCV67_RS00165	COG2217	Heavy metal translocating P-type atpase
BCV67_RS00170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCV67_RS00240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV67_RS00245	COG0443	Heat shock 70 kDa protein
BCV67_RS00250	COG0542	response to heat
BCV67_RS00260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV67_RS00265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCV67_RS00265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV67_RS00275	COG4993	Dehydrogenase
BCV67_RS00295	COG3039	Transposase
BCV67_RS00335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCV67_RS00350	COG2837	iron assimilation
BCV67_RS00380	COG2207	Transcriptional regulator
BCV67_RS00390	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV67_RS00445	COG5001	Diguanylate cyclase
BCV67_RS00445	COG5002	protein histidine kinase activity
BCV67_RS00475	COG0251	oxidation-reduction process
BCV67_RS00490	COG2211	Major facilitator Superfamily
BCV67_RS00495	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV67_RS00510	COG3661	Belongs to the glycosyl hydrolase 67 family
BCV67_RS00520	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV67_RS00525	COG0477	Major facilitator Superfamily
BCV67_RS00535	COG1070	Carbohydrate kinase
BCV67_RS00585	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BCV67_RS00595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCV67_RS00700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCV67_RS00720	COG2197	response regulator
BCV67_RS00735	COG3851	Histidine kinase
BCV67_RS00740	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV67_RS00745	COG3119	arylsulfatase activity
BCV67_RS00755	COG1064	alcohol dehydrogenase
BCV67_RS00770	COG2207	Transcriptional regulator
BCV67_RS00780	COG2197	response regulator
BCV67_RS00790	COG2197	response regulator
BCV67_RS00795	COG3188	usher protein
BCV67_RS00800	COG3121	Chaperone
BCV67_RS00810	COG3706	GGDEF domain
BCV67_RS00810	COG2203	Gaf domain
BCV67_RS00810	COG5001	Diguanylate cyclase
BCV67_RS00810	COG4251	negative regulation of phosphorylation
BCV67_RS00815	COG0784	Response regulator, receiver
BCV67_RS00815	COG2205	protein histidine kinase activity
BCV67_RS00865	COG2201	protein-glutamate methylesterase activity
BCV67_RS00870	COG2183	response to ionizing radiation
BCV67_RS00890	COG3243	poly(R)-hydroxyalkanoic acid synthase
BCV67_RS00900	COG1183	phosphatidylcholine synthase activity
BCV67_RS00915	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCV67_RS00925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCV67_RS00950	COG0084	hydrolase, TatD family'
BCV67_RS00955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV67_RS00990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV67_RS00990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCV67_RS01015	COG1595	DNA-templated transcription, initiation
BCV67_RS01020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV67_RS01025	COG2860	membrane
BCV67_RS01045	COG0386	Belongs to the glutathione peroxidase family
BCV67_RS01050	COG0339	signal peptide processing
BCV67_RS01055	COG1566	PFAM secretion protein HlyD family protein
BCV67_RS01070	COG1846	Transcriptional regulator
BCV67_RS01075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCV67_RS01095	COG3104	oligopeptide transport
BCV67_RS01105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV67_RS01125	COG0488	(ABC) transporter
BCV67_RS01130	COG0583	DNA-binding transcription factor activity
BCV67_RS01140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCV67_RS01145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV67_RS01165	COG3279	Response regulator of the LytR AlgR family
BCV67_RS01180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV67_RS01180	COG1017	nitric oxide dioxygenase activity
BCV67_RS01215	COG0318	PFAM AMP-dependent synthetase and ligase
BCV67_RS01225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BCV67_RS01235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BCV67_RS01245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCV67_RS01250	COG3115	cell septum assembly
BCV67_RS01260	COG0359	binds to the 23S rRNA
BCV67_RS01265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV67_RS01270	COG0360	Binds together with S18 to 16S ribosomal RNA
BCV67_RS01275	COG2814	Major facilitator Superfamily
BCV67_RS01280	COG0316	Belongs to the HesB IscA family
BCV67_RS01305	COG0288	reversible hydration of carbon dioxide
BCV67_RS01320	COG3844	kynureninase activity
BCV67_RS01325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV67_RS01330	COG2925	Exonuclease
BCV67_RS01365	COG2902	Dehydrogenase
BCV67_RS01380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS01385	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS01395	COG0646	methionine synthase
BCV67_RS01395	COG1410	methionine synthase
BCV67_RS01415	COG0583	DNA-binding transcription factor activity
BCV67_RS01420	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BCV67_RS01425	COG2814	Major facilitator Superfamily
BCV67_RS01430	COG2755	lipolytic protein G-D-S-L family
BCV67_RS01430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BCV67_RS01440	COG2900	Belongs to the SlyX family
BCV67_RS01455	COG0386	Belongs to the glutathione peroxidase family
BCV67_RS01460	COG1725	Transcriptional regulator
BCV67_RS01465	COG1131	(ABC) transporter
BCV67_RS01500	COG2850	peptidyl-arginine hydroxylation
BCV67_RS01510	COG0567	Dehydrogenase, E1 component
BCV67_RS01520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV67_RS01550	COG1132	(ABC) transporter
BCV67_RS01560	COG0287	Prephenate dehydrogenase
BCV67_RS01560	COG1605	Chorismate mutase
BCV67_RS01565	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BCV67_RS01570	COG0484	heat shock protein binding
BCV67_RS01575	COG0443	Heat shock 70 kDa protein
BCV67_RS01580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCV67_RS01585	COG0497	DNA recombination
BCV67_RS01595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV67_RS01600	COG2914	Belongs to the UPF0125 (RnfH) family
BCV67_RS01610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCV67_RS01640	COG2963	transposase activity
BCV67_RS01660	COG0582	viral genome integration into host DNA
BCV67_RS01705	COG0513	Belongs to the DEAD box helicase family
BCV67_RS01715	COG2201	protein-glutamate methylesterase activity
BCV67_RS01735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCV67_RS01740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCV67_RS01745	COG0625	glutathione transferase activity
BCV67_RS01750	COG1278	Cold shock
BCV67_RS01760	COG0564	pseudouridine synthase activity
BCV67_RS01765	COG4681	YaeQ
BCV67_RS01770	COG2081	HI0933 family
BCV67_RS01780	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV67_RS01785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV67_RS01795	COG1862	Preprotein translocase
BCV67_RS01800	COG0343	queuine tRNA-ribosyltransferase activity
BCV67_RS01805	COG3842	ATPase activity
BCV67_RS01810	COG1178	ABC-type Fe3 transport system permease component
BCV67_RS01815	COG1840	ABC-type Fe3 transport system, periplasmic component
BCV67_RS01820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCV67_RS01825	COG1522	sequence-specific DNA binding
BCV67_RS01830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV67_RS01855	COG0583	DNA-binding transcription factor activity
BCV67_RS01865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCV67_RS01890	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCV67_RS01895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV67_RS01900	COG0405	Gamma-glutamyltransferase
BCV67_RS01905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV67_RS01915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCV67_RS01920	COG0742	ribosomal rna small subunit methyltransferase
BCV67_RS01925	COG0326	Molecular chaperone. Has ATPase activity
BCV67_RS01930	COG0552	protein localization to endoplasmic reticulum
BCV67_RS01935	COG1194	a g-specific adenine glycosylase
BCV67_RS01940	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BCV67_RS01955	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV67_RS01980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCV67_RS02000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV67_RS02005	COG0837	glucose binding
BCV67_RS02010	COG0363	glucosamine-6-phosphate deaminase activity
BCV67_RS02015	COG0129	dihydroxy-acid dehydratase activity
BCV67_RS02020	COG0800	Aldolase
BCV67_RS02030	COG0395	ABC-type sugar transport system, permease component
BCV67_RS02055	COG1609	Transcriptional regulator
BCV67_RS02060	COG0271	Belongs to the BolA IbaG family
BCV67_RS02065	COG2350	Protein conserved in bacteria
BCV67_RS02075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCV67_RS02080	COG1187	pseudouridine synthase activity
BCV67_RS02115	COG0436	Aminotransferase
BCV67_RS02165	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BCV67_RS02170	COG1138	Cytochrome C-type biogenesis protein
BCV67_RS02190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV67_RS02200	COG1278	Cold shock
BCV67_RS02220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCV67_RS02225	COG4988	ABC transporter
BCV67_RS02235	COG1294	oxidase, subunit
BCV67_RS02275	COG0165	Argininosuccinate lyase
BCV67_RS02290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCV67_RS02295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV67_RS02300	COG0137	argininosuccinate synthase activity
BCV67_RS02305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCV67_RS02320	COG2166	iron-sulfur cluster assembly
BCV67_RS02330	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV67_RS02340	COG1309	transcriptional regulator
BCV67_RS02345	COG0590	tRNA wobble adenosine to inosine editing
BCV67_RS02355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCV67_RS02375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV67_RS02380	COG0402	S-adenosylhomocysteine deaminase activity
BCV67_RS02385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCV67_RS02390	COG1509	lysine 2,3-aminomutase activity
BCV67_RS02395	COG5001	Diguanylate cyclase
BCV67_RS02395	COG3300	MHYT domain
BCV67_RS02410	COG0483	inositol monophosphate 1-phosphatase activity
BCV67_RS02420	COG0501	Belongs to the peptidase M48B family
BCV67_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS02450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCV67_RS02460	COG0802	atpase or kinase
BCV67_RS02465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCV67_RS02465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCV67_RS02470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV67_RS02475	COG1570	exodeoxyribonuclease VII activity
BCV67_RS02520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV67_RS02530	COG1940	carbohydrate kinase activity
BCV67_RS02530	COG1846	Transcriptional regulator
BCV67_RS02535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV67_RS02545	COG4771	TonB-dependent receptor
BCV67_RS02550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCV67_RS02555	COG1473	amidohydrolase
BCV67_RS02560	COG1228	amidohydrolase
BCV67_RS02585	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS02595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCV67_RS02615	COG3040	lipid binding
BCV67_RS02655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCV67_RS02660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCV67_RS02670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCV67_RS02675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCV67_RS02700	COG0556	nucleotide-excision repair
BCV67_RS02705	COG4968	Prepilin-type N-terminal cleavage methylation domain
BCV67_RS02745	COG3275	phosphorelay sensor kinase activity
BCV67_RS02750	COG1611	Belongs to the LOG family
BCV67_RS02760	COG2095	MarC family integral membrane protein
BCV67_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS02770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV67_RS02780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV67_RS02815	COG2969	positive regulation of protein catabolic process
BCV67_RS02820	COG0625	glutathione transferase activity
BCV67_RS02825	COG2857	Cytochrome c1
BCV67_RS02830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCV67_RS02835	COG0723	plastoquinol--plastocyanin reductase activity
BCV67_RS02840	COG0741	lytic transglycosylase activity
BCV67_RS02850	COG1702	phosphate starvation-inducible protein PhoH
BCV67_RS02855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCV67_RS02865	COG4535	Mg2 and Co2 transporter CorC
BCV67_RS02880	COG0006	proline dipeptidase activity
BCV67_RS02885	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS02890	COG1177	transmembrane transport
BCV67_RS02895	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCV67_RS02900	COG3842	ATPase activity
BCV67_RS02915	COG0519	Catalyzes the synthesis of GMP from XMP
BCV67_RS02915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV67_RS02920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV67_RS02930	COG2703	oxygen carrier activity
BCV67_RS02935	COG0477	Major facilitator Superfamily
BCV67_RS02950	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS02970	COG2733	membrane
BCV67_RS02995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV67_RS02995	COG0116	Belongs to the methyltransferase superfamily
BCV67_RS03020	COG0494	nUDIX hydrolase
BCV67_RS03050	COG1024	Enoyl-CoA hydratase
BCV67_RS03060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV67_RS03075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV67_RS03080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV67_RS03085	COG0573	inorganic phosphate transmembrane transporter activity
BCV67_RS03090	COG0581	inorganic phosphate transmembrane transporter activity
BCV67_RS03100	COG0704	Plays a role in the regulation of phosphate uptake
BCV67_RS03110	COG3220	belongs to the UPF0276 family
BCV67_RS03120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV67_RS03125	COG3706	GGDEF domain
BCV67_RS03125	COG4251	negative regulation of phosphorylation
BCV67_RS03125	COG2203	Gaf domain
BCV67_RS03125	COG5001	Diguanylate cyclase
BCV67_RS03135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV67_RS03140	COG0557	exoribonuclease II activity
BCV67_RS03160	COG2814	Major facilitator Superfamily
BCV67_RS03165	COG1566	PFAM secretion protein HlyD family protein
BCV67_RS03190	COG2193	ferroxidase activity
BCV67_RS03205	COG0475	glutathione-regulated potassium exporter activity
BCV67_RS03210	COG0367	asparagine synthase
BCV67_RS03235	COG2203	Gaf domain
BCV67_RS03235	COG3706	GGDEF domain
BCV67_RS03235	COG4251	negative regulation of phosphorylation
BCV67_RS03235	COG5001	Diguanylate cyclase
BCV67_RS03245	COG1393	Belongs to the ArsC family
BCV67_RS03260	COG0024	Methionine aminopeptidase
BCV67_RS03275	COG3188	usher protein
BCV67_RS03305	COG0052	Belongs to the universal ribosomal protein uS2 family
BCV67_RS03320	COG0528	UMP kinase activity
BCV67_RS03330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCV67_RS03335	COG0575	Belongs to the CDS family
BCV67_RS03340	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCV67_RS03345	COG0750	zinc metalloprotease
BCV67_RS03350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV67_RS03355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV67_RS03365	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV67_RS03400	COG0825	malonyl-CoA metabolic process
BCV67_RS03410	COG1981	membrane
BCV67_RS03475	COG3321	synthase
BCV67_RS03475	COG0604	alcohol dehydrogenase
BCV67_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS03495	COG1132	(ABC) transporter
BCV67_RS03500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV67_RS03525	COG1187	pseudouridine synthase activity
BCV67_RS03530	COG2199	diguanylate cyclase activity
BCV67_RS03530	COG2203	Gaf domain
BCV67_RS03615	COG1228	amidohydrolase
BCV67_RS03620	COG0735	belongs to the Fur family
BCV67_RS03625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV67_RS03645	COG4452	Inner membrane protein CreD
BCV67_RS03650	COG2205	protein histidine kinase activity
BCV67_RS03655	COG0745	RESPONSE REGULATOR receiver
BCV67_RS03660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCV67_RS03670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV67_RS03710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV67_RS03730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV67_RS03735	COG1845	cytochrome c oxidase, subunit III
BCV67_RS03740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV67_RS03760	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS03770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BCV67_RS03775	COG0583	DNA-binding transcription factor activity
BCV67_RS03780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCV67_RS03790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCV67_RS03795	COG0196	riboflavin kinase activity
BCV67_RS03800	COG0728	peptidoglycan biosynthetic process
BCV67_RS03810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCV67_RS03825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCV67_RS03830	COG0824	Thioesterase
BCV67_RS03850	COG1024	Enoyl-CoA hydratase
BCV67_RS03855	COG1946	Acyl-CoA thioesterase
BCV67_RS03865	COG1595	DNA-templated transcription, initiation
BCV67_RS03875	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BCV67_RS03890	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BCV67_RS03915	COG1073	alpha beta
BCV67_RS03930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV67_RS03945	COG2197	response regulator
BCV67_RS03950	COG4585	Histidine kinase
BCV67_RS03960	COG0850	regulation of cytokinetic process
BCV67_RS03965	COG2894	cell division
BCV67_RS03980	COG2205	protein histidine kinase activity
BCV67_RS03985	COG0745	RESPONSE REGULATOR receiver
BCV67_RS03990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCV67_RS04000	COG2194	sulfuric ester hydrolase activity
BCV67_RS04035	COG4245	von Willebrand factor, type A
BCV67_RS04055	COG2814	Major facilitator Superfamily
BCV67_RS04060	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV67_RS04060	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV67_RS04075	COG2207	Transcriptional regulator
BCV67_RS04075	COG1917	Cupin 2, conserved barrel domain protein
BCV67_RS04100	COG0330	HflC and HflK could
BCV67_RS04105	COG0330	HflC and HflK could
BCV67_RS04110	COG0604	alcohol dehydrogenase
BCV67_RS04130	COG0678	peroxiredoxin activity
BCV67_RS04140	COG4953	penicillin-binding protein 1C
BCV67_RS04145	COG2373	Large extracellular alpha-helical protein
BCV67_RS04155	COG2852	Protein conserved in bacteria
BCV67_RS04180	COG0372	Belongs to the citrate synthase family
BCV67_RS04225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCV67_RS04235	COG2814	Major facilitator Superfamily
BCV67_RS04255	COG3038	cytochrome b561
BCV67_RS04275	COG1760	l-serine dehydratase
BCV67_RS04285	COG0460	homoserine dehydrogenase
BCV67_RS04285	COG0527	aspartate kinase activity
BCV67_RS04290	COG0626	cystathionine gamma-synthase activity
BCV67_RS04295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV67_RS04300	COG0739	heme binding
BCV67_RS04305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCV67_RS04310	COG1272	protein, Hemolysin III
BCV67_RS04315	COG2982	Protein involved in outer membrane biogenesis
BCV67_RS04320	COG0517	IMP dehydrogenase activity
BCV67_RS04325	COG0463	Glycosyl transferase, family 2
BCV67_RS04330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV67_RS04335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCV67_RS04345	COG4206	TonB-dependent receptor
BCV67_RS04355	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BCV67_RS04365	COG1309	transcriptional regulator
BCV67_RS04400	COG0501	Belongs to the peptidase M48B family
BCV67_RS04405	COG1704	LemA family
BCV67_RS04430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCV67_RS04440	COG0330	HflC and HflK could
BCV67_RS04455	COG3956	TIGRFAM MazG family protein
BCV67_RS04460	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCV67_RS04465	COG0494	nUDIX hydrolase
BCV67_RS04470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV67_RS04480	COG2201	protein-glutamate methylesterase activity
BCV67_RS04490	COG0840	transmembrane signaling receptor activity
BCV67_RS04495	COG0835	chemotaxis
BCV67_RS04510	COG0189	ligase activity
BCV67_RS04525	COG1199	ATP-dependent helicase activity
BCV67_RS04535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV67_RS04550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV67_RS04565	COG1643	Atp-dependent helicase
BCV67_RS04570	COG0783	Belongs to the Dps family
BCV67_RS04575	COG0514	ATP-dependent DNA helicase (RecQ)
BCV67_RS04595	COG2815	serine threonine protein kinase
BCV67_RS04595	COG0515	serine threonine protein kinase
BCV67_RS04615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCV67_RS04620	COG0602	queuosine metabolic process
BCV67_RS04630	COG2885	chlorophyll binding
BCV67_RS04645	COG0848	biopolymer transport protein
BCV67_RS04655	COG0824	Thioesterase
BCV67_RS04660	COG2255	four-way junction helicase activity
BCV67_RS04670	COG0632	four-way junction helicase activity
BCV67_RS04675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCV67_RS04690	COG4771	TonB-dependent receptor
BCV67_RS04695	COG1595	DNA-templated transcription, initiation
BCV67_RS04710	COG2963	transposase activity
BCV67_RS04720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCV67_RS04755	COG0488	(ABC) transporter
BCV67_RS04765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV67_RS04765	COG4651	solute:proton antiporter activity
BCV67_RS04780	COG2910	NAD(P)H-binding
BCV67_RS04790	COG0542	response to heat
BCV67_RS04830	COG3387	PFAM Glycoside hydrolase 15-related
BCV67_RS04835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BCV67_RS04840	COG3011	Protein conserved in bacteria
BCV67_RS04855	COG0564	pseudouridine synthase activity
BCV67_RS04860	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV67_RS04865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCV67_RS04865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV67_RS04870	COG2852	Protein conserved in bacteria
BCV67_RS04880	COG0045	succinate-CoA ligase (ADP-forming) activity
BCV67_RS04905	COG1459	type II secretion system
BCV67_RS04910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCV67_RS04920	COG0642	Histidine kinase
BCV67_RS04925	COG0745	RESPONSE REGULATOR receiver
BCV67_RS04930	COG0189	ligase activity
BCV67_RS04950	COG2022	thiamine diphosphate biosynthetic process
BCV67_RS04960	COG0471	metal ion transport
BCV67_RS04960	COG3273	potassium ion transport
BCV67_RS04980	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV67_RS04985	COG1970	mechanosensitive ion channel activity
BCV67_RS05005	COG1115	amino acid carrier protein
BCV67_RS05015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS05025	COG2895	sulfate adenylyltransferase (ATP) activity
BCV67_RS05025	COG0529	Catalyzes the synthesis of activated sulfate
BCV67_RS05035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV67_RS05045	COG0175	sulfate reduction
BCV67_RS05060	COG0583	DNA-binding transcription factor activity
BCV67_RS05075	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV67_RS05085	COG3588	fructose-bisphosphate aldolase
BCV67_RS05090	COG0469	pyruvate kinase activity
BCV67_RS05100	COG0126	phosphoglycerate kinase activity
BCV67_RS05105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV67_RS05120	COG1733	regulation of RNA biosynthetic process
BCV67_RS05130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV67_RS05150	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BCV67_RS05170	COG2885	chlorophyll binding
BCV67_RS05175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV67_RS05180	COG1301	dicarboxylic acid transport
BCV67_RS05210	COG0714	Associated with various cellular activities
BCV67_RS05240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCV67_RS05255	COG0254	rRNA binding
BCV67_RS05260	COG1957	nucleoside hydrolase
BCV67_RS05265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV67_RS05300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV67_RS05305	COG1758	RNA polymerase activity
BCV67_RS05315	COG1561	YicC-like family, N-terminal region
BCV67_RS05320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCV67_RS05325	COG0346	lactoylglutathione lyase activity
BCV67_RS05340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV67_RS05355	COG0006	proline dipeptidase activity
BCV67_RS05360	COG0006	proline dipeptidase activity
BCV67_RS05365	COG3079	Belongs to the UPF0149 family
BCV67_RS05385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV67_RS05405	COG2912	Transglutaminase-like superfamily
BCV67_RS05410	COG1773	rubredoxin
BCV67_RS05420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV67_RS05445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCV67_RS05450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV67_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS05470	COG0671	phosphoesterase, PA-phosphatase related
BCV67_RS05480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV67_RS05485	COG0563	adenylate kinase activity
BCV67_RS05500	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BCV67_RS05515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCV67_RS05530	COG4977	sequence-specific DNA binding
BCV67_RS05530	COG1917	Cupin 2, conserved barrel domain protein
BCV67_RS05535	COG3710	Transcriptional regulator
BCV67_RS05550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCV67_RS05555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV67_RS05560	COG0405	Gamma-glutamyltransferase
BCV67_RS05580	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCV67_RS05600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV67_RS05605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCV67_RS05615	COG0473	3-isopropylmalate dehydrogenase activity
BCV67_RS05620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV67_RS05645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCV67_RS05650	COG1538	Outer membrane efflux protein
BCV67_RS05655	COG1519	Transferase
BCV67_RS05660	COG1560	Kdo2-lipid A biosynthetic process
BCV67_RS05680	COG0612	Peptidase, M16
BCV67_RS05695	COG0280	phosphate acetyltransferase
BCV67_RS05695	COG0281	malic enzyme
BCV67_RS05700	COG1301	dicarboxylic acid transport
BCV67_RS05705	COG4191	Histidine kinase
BCV67_RS05725	COG2610	gluconate transmembrane transporter activity
BCV67_RS05730	COG1737	Transcriptional regulator
BCV67_RS05735	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BCV67_RS05745	COG0786	glutamate:sodium symporter activity
BCV67_RS05750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV67_RS05765	COG0436	Aminotransferase
BCV67_RS05785	COG0513	Belongs to the DEAD box helicase family
BCV67_RS05795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV67_RS05805	COG1307	EDD domain protein, DegV family
BCV67_RS05820	COG2203	Gaf domain
BCV67_RS05820	COG4251	negative regulation of phosphorylation
BCV67_RS05820	COG5001	Diguanylate cyclase
BCV67_RS05820	COG3706	GGDEF domain
BCV67_RS05825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BCV67_RS05830	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BCV67_RS05895	COG3279	Response regulator of the LytR AlgR family
BCV67_RS05935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCV67_RS05970	COG0741	lytic transglycosylase activity
BCV67_RS05990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV67_RS05995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV67_RS06000	COG1609	Transcriptional regulator
BCV67_RS06005	COG0738	Major facilitator superfamily
BCV67_RS06010	COG0837	glucose binding
BCV67_RS06020	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCV67_RS06025	COG0837	glucose binding
BCV67_RS06045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCV67_RS06060	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS06065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV67_RS06075	COG0784	Response regulator, receiver
BCV67_RS06080	COG4251	negative regulation of phosphorylation
BCV67_RS06085	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCV67_RS06105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCV67_RS06110	COG0321	lipoyl(octanoyl) transferase activity
BCV67_RS06115	COG2921	Belongs to the UPF0250 family
BCV67_RS06130	COG1686	Belongs to the peptidase S11 family
BCV67_RS06135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV67_RS06140	COG2951	lytic endotransglycosylase activity
BCV67_RS06145	COG0772	Belongs to the SEDS family
BCV67_RS06150	COG0768	penicillin binding
BCV67_RS06155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV67_RS06160	COG1792	Involved in formation and maintenance of cell shape
BCV67_RS06165	COG1077	Cell shape determining protein MreB Mrl
BCV67_RS06170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV67_RS06175	COG0546	phosphoglycolate phosphatase activity
BCV67_RS06200	COG0308	aminopeptidase N
BCV67_RS06205	COG2226	methyltransferase
BCV67_RS06220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS06225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS06230	COG1309	transcriptional regulator
BCV67_RS06280	COG3451	type IV secretory pathway VirB4
BCV67_RS06290	COG3838	Conjugal transfer protein Trbc
BCV67_RS06295	COG4962	Type ii secretion system protein e
BCV67_RS06330	COG0583	DNA-binding transcription factor activity
BCV67_RS06340	COG1733	regulation of RNA biosynthetic process
BCV67_RS06345	COG0251	oxidation-reduction process
BCV67_RS06360	COG4959	Type IV secretory pathway protease TraF
BCV67_RS06410	COG5489	Protein of unknown function (DUF736)
BCV67_RS06415	COG1475	DNA binding
BCV67_RS06430	COG2003	Belongs to the UPF0758 family
BCV67_RS06435	COG4804	nuclease activity
BCV67_RS06450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCV67_RS06455	COG4245	von Willebrand factor, type A
BCV67_RS06520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV67_RS06530	COG4581	dead DEAH box helicase
BCV67_RS06550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCV67_RS06560	COG2832	Protein of unknown function (DUF454)
BCV67_RS06570	COG0436	Aminotransferase
BCV67_RS06575	COG1505	serine-type exopeptidase activity
BCV67_RS06595	COG0339	signal peptide processing
BCV67_RS06600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV67_RS06610	COG2132	Multicopper oxidase
BCV67_RS06630	COG2871	sodium ion transport
BCV67_RS06655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV67_RS06665	COG1136	(ABC) transporter
BCV67_RS06670	COG0577	efflux transmembrane transporter activity
BCV67_RS06670	COG1136	(ABC) transporter
BCV67_RS06675	COG0577	efflux transmembrane transporter activity
BCV67_RS06680	COG1136	(ABC) transporter
BCV67_RS06680	COG0577	efflux transmembrane transporter activity
BCV67_RS06685	COG0577	efflux transmembrane transporter activity
BCV67_RS06690	COG0577	efflux transmembrane transporter activity
BCV67_RS06690	COG1136	(ABC) transporter
BCV67_RS06695	COG0577	efflux transmembrane transporter activity
BCV67_RS06710	COG2204	response regulator
BCV67_RS06715	COG4191	Histidine kinase
BCV67_RS06725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCV67_RS06735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCV67_RS06740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCV67_RS06750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCV67_RS06755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCV67_RS06760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCV67_RS06770	COG0356	it plays a direct role in the translocation of protons across the membrane
BCV67_RS06790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV67_RS06800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV67_RS06810	COG3047	cAMP biosynthetic process
BCV67_RS06830	COG2011	ABC-type metal ion transport system permease component
BCV67_RS06840	COG0697	spore germination
BCV67_RS06870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCV67_RS06875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BCV67_RS06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV67_RS06970	COG3118	belongs to the thioredoxin family
BCV67_RS06975	COG0459	protein refolding
BCV67_RS06980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCV67_RS06995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV67_RS07005	COG1053	succinate dehydrogenase
BCV67_RS07040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV67_RS07090	COG0393	Putative heavy-metal-binding
BCV67_RS07125	COG0583	DNA-binding transcription factor activity
BCV67_RS07145	COG0778	Nitroreductase
BCV67_RS07155	COG1666	GTP binding
BCV67_RS07180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV67_RS07185	COG1187	pseudouridine synthase activity
BCV67_RS07190	COG2813	Specifically methylates the guanine in position
BCV67_RS07200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV67_RS07200	COG2205	protein histidine kinase activity
BCV67_RS07215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV67_RS07230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV67_RS07265	COG0025	NhaP-type Na H and K H
BCV67_RS07270	COG3384	dioxygenase
BCV67_RS07285	COG3590	peptidase
BCV67_RS07310	COG3275	phosphorelay sensor kinase activity
BCV67_RS07325	COG4941	Belongs to the sigma-70 factor family
BCV67_RS07330	COG5507	3-demethylubiquinone-9 3-methyltransferase
BCV67_RS07340	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BCV67_RS07345	COG3795	YCII-related domain
BCV67_RS07350	COG3795	YCII-related domain
BCV67_RS07375	COG0741	lytic transglycosylase activity
BCV67_RS07400	COG0659	secondary active sulfate transmembrane transporter activity
BCV67_RS07440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV67_RS07445	COG1490	D-aminoacyl-tRNA deacylase activity
BCV67_RS07455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCV67_RS07495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV67_RS07495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCV67_RS07500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCV67_RS07505	COG0242	peptide deformylase activity
BCV67_RS07515	COG0758	DNA mediated transformation
BCV67_RS07530	COG1714	RDD family
BCV67_RS07535	COG1754	DNA topoisomerase type I activity
BCV67_RS07535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV67_RS07540	COG0009	L-threonylcarbamoyladenylate synthase
BCV67_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS07570	COG0616	signal peptide processing
BCV67_RS07575	COG0534	Mate efflux family protein
BCV67_RS07590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV67_RS07595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV67_RS07605	COG3250	beta-galactosidase activity
BCV67_RS07615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV67_RS07625	COG1609	Transcriptional regulator
BCV67_RS07630	COG3537	Alpha-1,2-mannosidase
BCV67_RS07640	COG0625	glutathione transferase activity
BCV67_RS07650	COG1252	NADH dehydrogenase
BCV67_RS07675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCV67_RS07680	COG2201	protein-glutamate methylesterase activity
BCV67_RS07685	COG2177	Part of the ABC transporter FtsEX involved in
BCV67_RS07690	COG2884	Cell division ATP-binding protein ftsE
BCV67_RS07700	COG3118	belongs to the thioredoxin family
BCV67_RS07705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV67_RS07710	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BCV67_RS07740	COG1652	LysM domain
BCV67_RS07745	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV67_RS07745	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV67_RS07755	COG1473	amidohydrolase
BCV67_RS07760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS07765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS07770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS07775	COG0753	catalase activity
BCV67_RS07780	COG3038	cytochrome b561
BCV67_RS07785	COG2197	response regulator
BCV67_RS07790	COG4585	Histidine kinase
BCV67_RS07800	COG1131	(ABC) transporter
BCV67_RS07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS07810	COG1136	(ABC) transporter
BCV67_RS07825	COG4206	TonB-dependent receptor
BCV67_RS07870	COG0739	heme binding
BCV67_RS07885	COG2223	nitrite transmembrane transporter activity
BCV67_RS07905	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BCV67_RS07910	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BCV67_RS07920	COG2205	protein histidine kinase activity
BCV67_RS07940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV67_RS07950	COG0018	arginyl-trna synthetase
BCV67_RS07965	COG4221	oxidoreductase activity
BCV67_RS07970	COG1166	arginine decarboxylase activity
BCV67_RS07995	COG2960	long-chain fatty acid transporting porin activity
BCV67_RS08000	COG0606	chelatase, subunit chli
BCV67_RS08045	COG2200	EAL domain
BCV67_RS08080	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BCV67_RS08080	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BCV67_RS08105	COG3135	benzoate transporter
BCV67_RS08110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV67_RS08115	COG0659	secondary active sulfate transmembrane transporter activity
BCV67_RS08125	COG0431	NADPH-dependent FMN reductase
BCV67_RS08140	COG0798	PFAM Bile acid sodium symporter
BCV67_RS08145	COG0492	ferredoxin-NADP+ reductase activity
BCV67_RS08150	COG2072	flavoprotein involved in K transport
BCV67_RS08160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV67_RS08165	COG0573	inorganic phosphate transmembrane transporter activity
BCV67_RS08180	COG0704	Plays a role in the regulation of phosphate uptake
BCV67_RS08200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV67_RS08250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV67_RS08305	COG4983	Phage plasmid primase, P4 family domain protein
BCV67_RS08335	COG0484	heat shock protein binding
BCV67_RS08380	COG0582	viral genome integration into host DNA
BCV67_RS08390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCV67_RS08400	COG1040	competence protein
BCV67_RS08405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCV67_RS08430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV67_RS08445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV67_RS08475	COG0714	Associated with various cellular activities
BCV67_RS08485	COG0754	glutathionylspermidine amidase activity
BCV67_RS08495	COG0129	dihydroxy-acid dehydratase activity
BCV67_RS08555	COG1187	pseudouridine synthase activity
BCV67_RS08565	COG0667	Aldo Keto reductase
BCV67_RS08575	COG0583	DNA-binding transcription factor activity
BCV67_RS08580	COG2814	Major facilitator Superfamily
BCV67_RS08585	COG0656	L-ascorbic acid biosynthetic process
BCV67_RS08595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV67_RS08595	COG1042	CoA-binding domain protein
BCV67_RS08595	COG0045	succinate-CoA ligase (ADP-forming) activity
BCV67_RS08600	COG2239	Acts as a magnesium transporter
BCV67_RS08620	COG0625	glutathione transferase activity
BCV67_RS08640	COG4555	ABC transporter
BCV67_RS08660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV67_RS08665	COG1131	(ABC) transporter
BCV67_RS08670	COG0842	Transport permease protein
BCV67_RS08675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCV67_RS08680	COG0084	hydrolase, TatD family'
BCV67_RS08685	COG1643	Atp-dependent helicase
BCV67_RS08695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCV67_RS08700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCV67_RS08710	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS08745	COG1335	isochorismatase
BCV67_RS08770	COG3474	cytochrome
BCV67_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS08805	COG0277	FAD linked oxidase domain protein
BCV67_RS08815	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS08835	COG2188	Transcriptional regulator
BCV67_RS08845	COG2267	carboxylic ester hydrolase activity
BCV67_RS08860	COG2271	Major facilitator Superfamily
BCV67_RS08865	COG2188	Transcriptional regulator
BCV67_RS08870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCV67_RS08875	COG0066	3-isopropylmalate dehydratase activity
BCV67_RS08890	COG2823	Periplasmic or secreted lipoprotein
BCV67_RS08915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCV67_RS08920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BCV67_RS08925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV67_RS08970	COG0183	Belongs to the thiolase family
BCV67_RS08980	COG2032	superoxide dismutase activity
BCV67_RS08985	COG2032	superoxide dismutase activity
BCV67_RS08995	COG2204	response regulator
BCV67_RS09000	COG3852	Histidine kinase
BCV67_RS09015	COG0004	ammonium transporteR
BCV67_RS09020	COG0347	Belongs to the P(II) protein family
BCV67_RS09025	COG0174	glutamine synthetase
BCV67_RS09060	COG2202	Pas domain
BCV67_RS09060	COG2199	diguanylate cyclase activity
BCV67_RS09060	COG2200	EAL domain
BCV67_RS09070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV67_RS09090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV67_RS09120	COG0431	NADPH-dependent FMN reductase
BCV67_RS09130	COG0798	PFAM Bile acid sodium symporter
BCV67_RS09135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV67_RS09140	COG0583	DNA-binding transcription factor activity
BCV67_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS09175	COG0583	DNA-binding transcription factor activity
BCV67_RS09195	COG0714	Associated with various cellular activities
BCV67_RS09240	COG0583	DNA-binding transcription factor activity
BCV67_RS09250	COG1335	isochorismatase
BCV67_RS09255	COG2031	fatty acid transporter
BCV67_RS09260	COG0628	permease
BCV67_RS09275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BCV67_RS09290	COG1505	serine-type exopeptidase activity
BCV67_RS09295	COG1205	dead DEAH box helicase
BCV67_RS09295	COG1111	helicase
BCV67_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS09340	COG0067	glutamate synthase
BCV67_RS09340	COG0069	glutamate synthase activity
BCV67_RS09340	COG0070	glutamate synthase
BCV67_RS09345	COG0493	'glutamate synthase
BCV67_RS09355	COG1803	Methylglyoxal synthase
BCV67_RS09445	COG3135	benzoate transporter
BCV67_RS09455	COG2951	lytic endotransglycosylase activity
BCV67_RS09470	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV67_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS09485	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BCV67_RS09505	COG0302	gtp cyclohydrolase
BCV67_RS09510	COG4993	Dehydrogenase
BCV67_RS09520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV67_RS09525	COG1074	ATP-dependent DNA helicase activity
BCV67_RS09530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCV67_RS09550	COG1127	ABC transporter
BCV67_RS09555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV67_RS09560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV67_RS09575	COG2853	Lipoprotein
BCV67_RS09580	COG0386	Belongs to the glutathione peroxidase family
BCV67_RS09585	COG1322	Protein conserved in bacteria
BCV67_RS09600	COG0531	amino acid
BCV67_RS09610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV67_RS09615	COG0861	Integral membrane protein TerC family
BCV67_RS09625	COG0584	glycerophosphoryl diester phosphodiesterase
BCV67_RS09630	COG0488	(ABC) transporter
BCV67_RS09655	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCV67_RS09660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCV67_RS09665	COG0592	DNA-directed DNA polymerase activity
BCV67_RS09670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV67_RS09675	COG0187	DNA topoisomerase II activity
BCV67_RS09685	COG0501	Belongs to the peptidase M48B family
BCV67_RS09725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV67_RS09735	COG1289	transmembrane transporter activity
BCV67_RS09745	COG1566	PFAM secretion protein HlyD family protein
BCV67_RS09770	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BCV67_RS09785	COG4772	TonB-dependent receptor
BCV67_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS09805	COG3284	Transcriptional regulator
BCV67_RS09810	COG0800	Aldolase
BCV67_RS09815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV67_RS09820	COG4771	TonB-dependent receptor
BCV67_RS09845	COG2272	Belongs to the type-B carboxylesterase lipase family
BCV67_RS09860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BCV67_RS09875	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV67_RS09880	COG1609	Transcriptional regulator
BCV67_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS09895	COG2755	lipolytic protein G-D-S-L family
BCV67_RS09905	COG0583	DNA-binding transcription factor activity
BCV67_RS09910	COG1741	Belongs to the pirin family
BCV67_RS09965	COG2197	response regulator
BCV67_RS09970	COG4585	Histidine kinase
BCV67_RS09980	COG3186	Phenylalanine-4-hydroxylase
BCV67_RS09990	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV67_RS10005	COG4771	TonB-dependent receptor
BCV67_RS10045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV67_RS10050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BCV67_RS10060	COG0210	DNA helicase
BCV67_RS10075	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCV67_RS10080	COG0284	orotidine-5'-phosphate decarboxylase activity
BCV67_RS10090	COG2937	Belongs to the GPAT DAPAT family
BCV67_RS10100	COG0037	tRNA processing
BCV67_RS10105	COG2974	May be involved in recombination
BCV67_RS10115	COG0840	transmembrane signaling receptor activity
BCV67_RS10125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCV67_RS10145	COG0805	protein transport
BCV67_RS10155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCV67_RS10175	COG0519	Catalyzes the synthesis of GMP from XMP
BCV67_RS10175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV67_RS10180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV67_RS10185	COG0752	glycyl-tRNA synthetase alpha subunit
BCV67_RS10200	COG0457	Tetratricopeptide repeat
BCV67_RS10205	COG4771	TonB-dependent receptor
BCV67_RS10210	COG0729	surface antigen
BCV67_RS10215	COG2911	Protein conserved in bacteria
BCV67_RS10245	COG0784	Response regulator, receiver
BCV67_RS10245	COG2205	protein histidine kinase activity
BCV67_RS10250	COG1971	Probably functions as a manganese efflux pump
BCV67_RS10275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV67_RS10290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCV67_RS10300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCV67_RS10315	COG4774	siderophore transport
BCV67_RS10320	COG0583	DNA-binding transcription factor activity
BCV67_RS10325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV67_RS10330	COG2301	Belongs to the HpcH HpaI aldolase family
BCV67_RS10335	COG4735	regulation of single-species biofilm formation
BCV67_RS10345	COG0732	type I restriction modification DNA specificity domain
BCV67_RS10360	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BCV67_RS10380	COG0357	Ribosomal RNA small subunit methyltransferase G
BCV67_RS10385	COG1192	Involved in chromosome partitioning
BCV67_RS10390	COG1475	DNA binding
BCV67_RS10410	COG0463	Glycosyl transferase, family 2
BCV67_RS10435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS10460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV67_RS10465	COG1819	glycosyl
BCV67_RS10475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCV67_RS10480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCV67_RS10490	COG0210	DNA helicase
BCV67_RS10495	COG0589	response to stress
BCV67_RS10510	COG2323	membrane
BCV67_RS10515	COG0408	coproporphyrinogen oxidase activity
BCV67_RS10540	COG1271	oxidase subunit
BCV67_RS10545	COG1294	oxidase, subunit
BCV67_RS10550	COG0318	PFAM AMP-dependent synthetase and ligase
BCV67_RS10570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV67_RS10610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV67_RS10635	COG3781	membrane
BCV67_RS10655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV67_RS10665	COG1199	ATP-dependent helicase activity
BCV67_RS10690	COG1113	amino acid transport
BCV67_RS10745	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS10750	COG2130	NADP-dependent
BCV67_RS10760	COG0277	FAD linked oxidase domain protein
BCV67_RS10795	COG0681	Belongs to the peptidase S26 family
BCV67_RS10805	COG2186	Transcriptional regulator
BCV67_RS10810	COG1304	FMN binding
BCV67_RS10815	COG0277	FAD linked oxidase domain protein
BCV67_RS10825	COG2814	Major facilitator Superfamily
BCV67_RS10830	COG0583	DNA-binding transcription factor activity
BCV67_RS10835	COG0583	DNA-binding transcription factor activity
BCV67_RS10840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCV67_RS10870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCV67_RS10875	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS10895	COG0697	spore germination
BCV67_RS10905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV67_RS10925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV67_RS10930	COG1607	acyl-coa hydrolase
BCV67_RS10940	COG1902	pentaerythritol trinitrate reductase activity
BCV67_RS10945	COG0583	DNA-binding transcription factor activity
BCV67_RS10960	COG1335	isochorismatase
BCV67_RS10970	COG2076	Multidrug Resistance protein
BCV67_RS10985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV67_RS11015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BCV67_RS11015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BCV67_RS11020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCV67_RS11035	COG3437	response regulator, receiver
BCV67_RS11055	COG0517	IMP dehydrogenase activity
BCV67_RS11080	COG3237	CsbD-like
BCV67_RS11090	COG0180	Tryptophanyl-tRNA synthetase
BCV67_RS11110	COG0477	Major facilitator Superfamily
BCV67_RS11115	COG0697	spore germination
BCV67_RS11140	COG4942	peptidase
BCV67_RS11145	COG0793	Belongs to the peptidase S41A family
BCV67_RS11170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV67_RS11175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV67_RS11185	COG1845	cytochrome c oxidase, subunit III
BCV67_RS11225	COG0358	DNA primase activity
BCV67_RS11235	COG1610	YqeY-like protein
BCV67_RS11245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCV67_RS11250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV67_RS11255	COG0668	transmembrane transport
BCV67_RS11270	COG2133	pyrroloquinoline quinone binding
BCV67_RS11275	COG4682	membrane
BCV67_RS11290	COG1737	Transcriptional regulator
BCV67_RS11300	COG4948	Mandelate Racemase Muconate Lactonizing
BCV67_RS11350	COG5383	Protein conserved in bacteria
BCV67_RS11355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCV67_RS11365	COG0628	permease
BCV67_RS11385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV67_RS11415	COG1943	Transposase
BCV67_RS11435	COG1902	pentaerythritol trinitrate reductase activity
BCV67_RS11500	COG4993	Dehydrogenase
BCV67_RS11505	COG4260	virion core protein, lumpy skin disease virus
BCV67_RS11515	COG5507	3-demethylubiquinone-9 3-methyltransferase
BCV67_RS11545	COG0789	Transcriptional regulator
BCV67_RS11560	COG4807	Protein conserved in bacteria
BCV67_RS11575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV67_RS11575	COG0723	plastoquinol--plastocyanin reductase activity
BCV67_RS11590	COG3264	Mechanosensitive ion channel
BCV67_RS11590	COG1196	nuclear chromosome segregation
BCV67_RS11595	COG1368	sulfuric ester hydrolase activity
BCV67_RS11600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCV67_RS11605	COG2354	Protein conserved in bacteria
BCV67_RS11625	COG0702	epimerase
BCV67_RS11630	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS11670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCV67_RS11675	COG3483	tryptophan 2,3-dioxygenase activity
BCV67_RS11680	COG3104	oligopeptide transport
BCV67_RS11705	COG2852	Protein conserved in bacteria
BCV67_RS11710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BCV67_RS11725	COG0530	calcium, potassium:sodium antiporter activity
BCV67_RS11730	COG1320	monovalent cation:proton antiporter activity
BCV67_RS11735	COG2212	antiporter activity
BCV67_RS11745	COG0651	ATP synthesis coupled electron transport
BCV67_RS11750	COG1006	Multisubunit Na H antiporter MnhC subunit
BCV67_RS11755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV67_RS11755	COG2111	Na H antiporter
BCV67_RS11765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCV67_RS11770	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCV67_RS11785	COG1597	lipid kinase activity
BCV67_RS11800	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV67_RS11805	COG1280	lysine exporter protein (LysE YggA)
BCV67_RS11815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV67_RS11820	COG0134	indole-3-glycerol-phosphate synthase activity
BCV67_RS11830	COG0730	response to heat
BCV67_RS11835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV67_RS11840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCV67_RS11850	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BCV67_RS11855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCV67_RS11860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCV67_RS11880	COG1051	belongs to the nudix hydrolase family
BCV67_RS11920	COG0316	Belongs to the HesB IscA family
BCV67_RS11960	COG2814	Major facilitator Superfamily
BCV67_RS11965	COG1289	transmembrane transporter activity
BCV67_RS11975	COG0667	Aldo Keto reductase
BCV67_RS11980	COG0151	Belongs to the GarS family
BCV67_RS12000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BCV67_RS12010	COG2264	protein methyltransferase activity
BCV67_RS12025	COG0439	Biotin carboxylase
BCV67_RS12030	COG0511	ligase activity, forming carbon-carbon bonds
BCV67_RS12040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCV67_RS12045	COG1309	transcriptional regulator
BCV67_RS12055	COG1764	response to oxidative stress
BCV67_RS12060	COG3321	synthase
BCV67_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS12060	COG0604	alcohol dehydrogenase
BCV67_RS12065	COG3119	arylsulfatase activity
BCV67_RS12075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV67_RS12125	COG1999	signal sequence binding
BCV67_RS12130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV67_RS12135	COG1845	cytochrome c oxidase, subunit III
BCV67_RS12145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV67_RS12150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV67_RS12165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV67_RS12180	COG0427	acetyl-CoA hydrolase
BCV67_RS12200	COG0154	amidase activity
BCV67_RS12210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV67_RS12220	COG0612	Peptidase, M16
BCV67_RS12230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV67_RS12235	COG0596	Alpha beta hydrolase
BCV67_RS12250	COG0318	PFAM AMP-dependent synthetase and ligase
BCV67_RS12255	COG2852	Protein conserved in bacteria
BCV67_RS12260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV67_RS12270	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV67_RS12285	COG0564	pseudouridine synthase activity
BCV67_RS12330	COG0339	signal peptide processing
BCV67_RS12350	COG2375	cellular response to nickel ion
BCV67_RS12365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCV67_RS12370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCV67_RS12400	COG3214	Protein conserved in bacteria
BCV67_RS12455	COG2409	Drug exporters of the RND superfamily
BCV67_RS12460	COG3237	CsbD-like
BCV67_RS12480	COG0181	hydroxymethylbilane synthase activity
BCV67_RS12505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV67_RS12510	COG0546	phosphoglycolate phosphatase activity
BCV67_RS12520	COG4206	TonB-dependent receptor
BCV67_RS12525	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BCV67_RS12535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BCV67_RS12545	COG1956	GAF domain-containing protein
BCV67_RS12555	COG0720	synthase
BCV67_RS12560	COG4206	TonB-dependent receptor
BCV67_RS12570	COG0513	Belongs to the DEAD box helicase family
BCV67_RS12580	COG0625	glutathione transferase activity
BCV67_RS12610	COG0626	cystathionine gamma-synthase activity
BCV67_RS12625	COG0438	transferase activity, transferring glycosyl groups
BCV67_RS12645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCV67_RS12655	COG0110	maltose O-acetyltransferase activity
BCV67_RS12670	COG0463	Glycosyl transferase, family 2
BCV67_RS12675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV67_RS12715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV67_RS12745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV67_RS12745	COG3218	ABC-type transport auxiliary lipoprotein component
BCV67_RS12750	COG1127	ABC transporter
BCV67_RS12755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV67_RS12770	COG0442	prolyl-tRNA aminoacylation
BCV67_RS12780	COG1183	phosphatidylcholine synthase activity
BCV67_RS12800	COG0525	valine-tRNA ligase activity
BCV67_RS12815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCV67_RS12825	COG0795	lipopolysaccharide-transporting ATPase activity
BCV67_RS12835	COG4974	Belongs to the 'phage' integrase family
BCV67_RS12840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV67_RS12850	COG0047	phosphoribosylformylglycinamidine synthase activity
BCV67_RS12850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCV67_RS12855	COG5295	Hep Hag repeat protein
BCV67_RS12860	COG1404	Belongs to the peptidase S8 family
BCV67_RS12870	COG1404	Belongs to the peptidase S8 family
BCV67_RS12875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV67_RS12880	COG1459	type II secretion system
BCV67_RS12885	COG2165	general secretion pathway protein
BCV67_RS12890	COG4970	Tfp pilus assembly protein FimT
BCV67_RS12895	COG2165	general secretion pathway protein
BCV67_RS12900	COG4795	General secretion pathway protein
BCV67_RS12905	COG3156	type II secretion system protein K
BCV67_RS12910	COG3166	PFAM Fimbrial assembly family protein
BCV67_RS12925	COG1450	Type ii and iii secretion system protein
BCV67_RS12940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCV67_RS12995	COG0728	peptidoglycan biosynthetic process
BCV67_RS13005	COG3539	Fimbrial protein
BCV67_RS13030	COG2252	PERMEase
BCV67_RS13035	COG0488	(ABC) transporter
BCV67_RS13055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCV67_RS13075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV67_RS13075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV67_RS13095	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCV67_RS13100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV67_RS13130	COG0277	FAD linked oxidase domain protein
BCV67_RS13135	COG1988	membrane-bound metal-dependent
BCV67_RS13140	COG0792	nuclease activity
BCV67_RS13170	COG2001	Belongs to the MraZ family
BCV67_RS13175	COG0275	rRNA processing
BCV67_RS13180	COG3116	cell division
BCV67_RS13195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV67_RS13200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV67_RS13210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV67_RS13220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCV67_RS13235	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCV67_RS13245	COG0739	heme binding
BCV67_RS13250	COG0653	protein targeting
BCV67_RS13255	COG0494	nUDIX hydrolase
BCV67_RS13265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCV67_RS13275	COG0531	amino acid
BCV67_RS13350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCV67_RS13360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BCV67_RS13365	COG1607	acyl-coa hydrolase
BCV67_RS13370	COG4589	Belongs to the CDS family
BCV67_RS13385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCV67_RS13405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV67_RS13425	COG4106	trans-aconitate 2-methyltransferase activity
BCV67_RS13435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV67_RS13445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV67_RS13450	COG0667	Aldo Keto reductase
BCV67_RS13460	COG4771	TonB-dependent receptor
BCV67_RS13480	COG0642	Histidine kinase
BCV67_RS13485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV67_RS13490	COG0861	Integral membrane protein TerC family
BCV67_RS13525	COG3738	Protein conserved in bacteria
BCV67_RS13530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV67_RS13535	COG2967	ApaG domain
BCV67_RS13540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCV67_RS13545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCV67_RS13550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV67_RS13555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV67_RS13565	COG2096	Adenosyltransferase
BCV67_RS13575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV67_RS13580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV67_RS13585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV67_RS13605	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BCV67_RS13620	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS13625	COG2851	Citrate transporter
BCV67_RS13640	COG0642	Histidine kinase
BCV67_RS13655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV67_RS13670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV67_RS13685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV67_RS13690	COG0583	DNA-binding transcription factor activity
BCV67_RS13695	COG3634	alkyl hydroperoxide reductase activity
BCV67_RS13735	COG0778	Nitroreductase
BCV67_RS13745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCV67_RS13780	COG2207	Transcriptional regulator
BCV67_RS13790	COG0457	Tetratricopeptide repeat
BCV67_RS13810	COG2151	metal-sulfur cluster biosynthetic enzyme
BCV67_RS13815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV67_RS13820	COG1404	Belongs to the peptidase S8 family
BCV67_RS13825	COG1404	Belongs to the peptidase S8 family
BCV67_RS13830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV67_RS13850	COG1295	ribonuclease BN
BCV67_RS13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV67_RS13870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCV67_RS13875	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCV67_RS13885	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BCV67_RS13890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCV67_RS13900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCV67_RS13905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCV67_RS13910	COG0193	aminoacyl-tRNA hydrolase activity
BCV67_RS13915	COG0012	GTP binding
BCV67_RS13925	COG3340	Belongs to the peptidase S51 family
BCV67_RS13930	COG1446	asparaginase
BCV67_RS13950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV67_RS13965	COG0250	Participates in transcription elongation, termination and antitermination
BCV67_RS13970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCV67_RS13975	COG0081	regulation of translation
BCV67_RS13980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCV67_RS13985	COG0222	ribosome binding
BCV67_RS13990	COG0085	RNA polymerase activity
BCV67_RS13995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCV67_RS14000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCV67_RS14005	COG0049	tRNA binding
BCV67_RS14010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCV67_RS14015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV67_RS14020	COG0051	transcription antitermination factor activity, RNA binding
BCV67_RS14025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCV67_RS14030	COG0088	Forms part of the polypeptide exit tunnel
BCV67_RS14035	COG0089	rRNA binding
BCV67_RS14040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCV67_RS14045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCV67_RS14050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCV67_RS14055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCV67_RS14060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCV67_RS14065	COG0255	Belongs to the universal ribosomal protein uL29 family
BCV67_RS14070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCV67_RS14080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCV67_RS14085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCV67_RS14090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCV67_RS14095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCV67_RS14100	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCV67_RS14105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCV67_RS14110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCV67_RS14115	COG1841	ribosomal large subunit assembly
BCV67_RS14125	COG0201	protein transport
BCV67_RS14130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCV67_RS14140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCV67_RS14145	COG0202	RNA polymerase activity
BCV67_RS14150	COG0203	ribosomal protein L17
BCV67_RS14155	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BCV67_RS14160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BCV67_RS14175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV67_RS14190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV67_RS14205	COG5002	protein histidine kinase activity
BCV67_RS14210	COG0745	RESPONSE REGULATOR receiver
BCV67_RS14225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV67_RS14230	COG0625	glutathione transferase activity
BCV67_RS14240	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCV67_RS14240	COG1902	pentaerythritol trinitrate reductase activity
BCV67_RS14270	COG1187	pseudouridine synthase activity
BCV67_RS14290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCV67_RS14295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCV67_RS14300	COG4208	sulfate ABC transporter
BCV67_RS14305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCV67_RS14315	COG1063	alcohol dehydrogenase
BCV67_RS14330	COG0406	alpha-ribazole phosphatase activity
BCV67_RS14335	COG0285	dihydrofolate synthase activity
BCV67_RS14355	COG2833	Protein of unknown function (DUF455)
BCV67_RS14365	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV67_RS14375	COG0438	transferase activity, transferring glycosyl groups
BCV67_RS14380	COG0248	Ppx GppA phosphatase
BCV67_RS14385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCV67_RS14400	COG4783	chaperone-mediated protein folding
BCV67_RS14415	COG0473	3-isopropylmalate dehydrogenase activity
BCV67_RS14455	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCV67_RS14460	COG0740	serine-type endopeptidase activity
BCV67_RS14465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCV67_RS14500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV67_RS14505	COG3942	CHAP domain
BCV67_RS14505	COG1388	LysM domain
BCV67_RS14510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV67_RS14515	COG2226	methyltransferase
BCV67_RS14525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV67_RS14530	COG0631	protein serine/threonine phosphatase activity
BCV67_RS14540	COG0582	viral genome integration into host DNA
BCV67_RS14565	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV67_RS14580	COG2003	Belongs to the UPF0758 family
BCV67_RS14585	COG5377	YqaJ viral recombinase family
BCV67_RS14595	COG2963	transposase activity
BCV67_RS14600	COG2801	Transposase and inactivated derivatives
BCV67_RS14640	COG1393	Belongs to the ArsC family
BCV67_RS14645	COG0798	PFAM Bile acid sodium symporter
BCV67_RS14655	COG0346	lactoylglutathione lyase activity
BCV67_RS14660	COG0640	Transcriptional regulator
BCV67_RS14680	COG0642	Histidine kinase
BCV67_RS14690	COG3038	cytochrome b561
BCV67_RS14715	COG0798	PFAM Bile acid sodium symporter
BCV67_RS14730	COG0431	NADPH-dependent FMN reductase
BCV67_RS14735	COG1393	Belongs to the ArsC family
BCV67_RS14750	COG2003	Belongs to the UPF0758 family
BCV67_RS14795	COG2801	Transposase and inactivated derivatives
BCV67_RS14820	COG2963	transposase activity
BCV67_RS14825	COG2801	Transposase and inactivated derivatives
BCV67_RS14840	COG4716	Myosin-crossreactive antigen
BCV67_RS14845	COG0582	viral genome integration into host DNA
BCV67_RS14855	COG0859	PFAM glycosyl transferase family 9
BCV67_RS14860	COG3642	lipopolysaccharide core region biosynthetic process
BCV67_RS14865	COG1234	tRNA 3'-trailer cleavage
BCV67_RS14885	COG3537	Alpha-1,2-mannosidase
BCV67_RS14890	COG2336	PFAM SpoVT AbrB
BCV67_RS14920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCV67_RS14935	COG0537	adenosine 5'-monophosphoramidase activity
BCV67_RS14950	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BCV67_RS14955	COG0714	Associated with various cellular activities
BCV67_RS14970	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV67_RS14975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCV67_RS14980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV67_RS14985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV67_RS15005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV67_RS15010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV67_RS15090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV67_RS15105	COG0519	Catalyzes the synthesis of GMP from XMP
BCV67_RS15110	COG1678	Uncharacterized ACR, COG1678
BCV67_RS15120	COG0540	Belongs to the ATCase OTCase family
BCV67_RS15140	COG2239	Acts as a magnesium transporter
BCV67_RS15145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV67_RS15150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV67_RS15160	COG1660	Displays ATPase and GTPase activities
BCV67_RS15165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCV67_RS15170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV67_RS15185	COG1137	ATPase activity
BCV67_RS15190	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BCV67_RS15200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCV67_RS15215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCV67_RS15235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV67_RS15245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCV67_RS15255	COG0628	permease
BCV67_RS15265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCV67_RS15285	COG1555	photosystem II stabilization
BCV67_RS15290	COG2610	gluconate transmembrane transporter activity
BCV67_RS15295	COG4771	TonB-dependent receptor
BCV67_RS15300	COG2205	protein histidine kinase activity
BCV67_RS15305	COG0640	Transcriptional regulator
BCV67_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
BCV67_RS15345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV67_RS15350	COG1477	protein flavinylation
BCV67_RS15370	COG4771	TonB-dependent receptor
BCV67_RS15380	COG3128	pkhd-type hydroxylase
BCV67_RS15390	COG4774	siderophore transport
BCV67_RS15410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV67_RS15415	COG0719	Fe-S assembly protein
BCV67_RS15420	COG0396	ATPase activity
BCV67_RS15430	COG0719	Fe-S assembly protein
BCV67_RS15435	COG1959	2 iron, 2 sulfur cluster binding
BCV67_RS15460	COG1764	response to oxidative stress
BCV67_RS15470	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BCV67_RS15475	COG4771	TonB-dependent receptor
BCV67_RS15505	COG0384	phenazine biosynthesis protein PhzF
BCV67_RS15510	COG0384	phenazine biosynthesis protein PhzF
BCV67_RS15520	COG0527	aspartate kinase activity
BCV67_RS15530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCV67_RS15545	COG0142	geranyltranstransferase activity
BCV67_RS15550	COG0366	Alpha amylase catalytic
BCV67_RS15565	COG1082	Xylose isomerase domain protein TIM barrel
BCV67_RS15570	COG2190	(PTS) system
BCV67_RS15570	COG2211	Major facilitator Superfamily
BCV67_RS15585	COG1609	Transcriptional regulator
BCV67_RS15590	COG0629	single-stranded DNA binding
BCV67_RS15625	COG0673	inositol 2-dehydrogenase activity
BCV67_RS15630	COG2211	Major facilitator Superfamily
BCV67_RS15640	COG1609	Transcriptional regulator
BCV67_RS15645	COG2831	hemolysin activation secretion protein
BCV67_RS15650	COG3210	domain, Protein
BCV67_RS15650	COG3210	domain, Protein
BCV67_RS15665	COG1280	lysine exporter protein (LysE YggA)
BCV67_RS15670	COG3104	oligopeptide transport
BCV67_RS15675	COG1297	OPT oligopeptide transporter protein
BCV67_RS15680	COG0823	Involved in the tonB-independent uptake of proteins
BCV67_RS15680	COG1506	peptidase
BCV67_RS15700	COG2879	small protein
BCV67_RS15705	COG1966	Carbon starvation protein
BCV67_RS15710	COG1741	Belongs to the pirin family
BCV67_RS15725	COG1741	Belongs to the pirin family
BCV67_RS15730	COG0588	phosphoglycerate mutase activity
BCV67_RS15760	COG2207	Transcriptional regulator
BCV67_RS15765	COG2223	nitrite transmembrane transporter activity
BCV67_RS15770	COG2223	nitrite transmembrane transporter activity
BCV67_RS15775	COG4221	oxidoreductase activity
BCV67_RS15790	COG3590	peptidase
BCV67_RS15795	COG0024	Methionine aminopeptidase
BCV67_RS15810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCV67_RS15815	COG0336	Belongs to the RNA methyltransferase TrmD family
BCV67_RS15820	COG0335	large ribosomal subunit rRNA binding
BCV67_RS15825	COG2814	Major facilitator Superfamily
BCV67_RS15835	COG1349	DNA-binding transcription factor activity
BCV67_RS15845	COG1940	carbohydrate kinase activity
BCV67_RS15850	COG2222	sugar isomerase
BCV67_RS15865	COG0673	inositol 2-dehydrogenase activity
BCV67_RS15870	COG0534	Mate efflux family protein
BCV67_RS15875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCV67_RS15885	COG0753	catalase activity
BCV67_RS15890	COG2378	regulation of single-species biofilm formation
BCV67_RS15895	COG0625	glutathione transferase activity
BCV67_RS15900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCV67_RS15905	COG4771	TonB-dependent receptor
BCV67_RS15910	COG0531	amino acid
BCV67_RS15925	COG0531	amino acid
BCV67_RS15940	COG3706	GGDEF domain
BCV67_RS15945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV67_RS15975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV67_RS15980	COG0481	GTPase activity
BCV67_RS15985	COG0681	Belongs to the peptidase S26 family
BCV67_RS16000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCV67_RS16005	COG1381	Involved in DNA repair and RecF pathway recombination
BCV67_RS16010	COG2198	Histidine kinase
BCV67_RS16010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV67_RS16010	COG0784	Response regulator, receiver
BCV67_RS16010	COG2205	protein histidine kinase activity
BCV67_RS16015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCV67_RS16020	COG2954	triphosphatase activity
BCV67_RS16030	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV67_RS16035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCV67_RS16040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BCV67_RS16045	COG1278	Cold shock
BCV67_RS16050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV67_RS16055	COG1960	acyl-CoA dehydrogenase activity
BCV67_RS16075	COG0183	Belongs to the thiolase family
BCV67_RS16090	COG1703	isobutyryl-CoA mutase activity
BCV67_RS16090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCV67_RS16090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCV67_RS16095	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCV67_RS16110	COG3300	MHYT domain
BCV67_RS16110	COG5001	Diguanylate cyclase
BCV67_RS16120	COG0204	Acyl-transferase
BCV67_RS16155	COG3300	MHYT domain
BCV67_RS16155	COG5001	Diguanylate cyclase
BCV67_RS16185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV67_RS16190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BCV67_RS16210	COG1451	nucleotide metabolic process
BCV67_RS16215	COG3122	Protein conserved in bacteria
BCV67_RS16220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV67_RS16245	COG1595	DNA-templated transcription, initiation
BCV67_RS16260	COG1077	Cell shape determining protein MreB Mrl
BCV67_RS16270	COG2824	Alkylphosphonate utilization operon protein PhnA
BCV67_RS16300	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCV67_RS16300	COG0392	lysyltransferase activity
BCV67_RS16305	COG0251	oxidation-reduction process
BCV67_RS16315	COG2878	Part of a membrane complex involved in electron transport
BCV67_RS16325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV67_RS16325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV67_RS16340	COG1131	(ABC) transporter
BCV67_RS16350	COG0346	lactoylglutathione lyase activity
BCV67_RS16375	COG5001	Diguanylate cyclase
BCV67_RS16375	COG3706	GGDEF domain
BCV67_RS16375	COG4251	negative regulation of phosphorylation
BCV67_RS16375	COG2203	Gaf domain
BCV67_RS16385	COG3118	belongs to the thioredoxin family
BCV67_RS16430	COG4964	Belongs to the GSP D family
BCV67_RS16475	COG0495	leucyl-tRNA aminoacylation
BCV67_RS16490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCV67_RS16500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCV67_RS16520	COG2968	Membrane
BCV67_RS16540	COG0312	modulator of DNA gyrase
BCV67_RS16545	COG3028	Belongs to the UPF0307 family
BCV67_RS16550	COG0312	modulator of DNA gyrase
BCV67_RS16560	COG0142	geranyltranstransferase activity
BCV67_RS16565	COG1722	exodeoxyribonuclease VII activity
BCV67_RS16585	COG1301	dicarboxylic acid transport
BCV67_RS16620	COG2204	response regulator
BCV67_RS16625	COG0791	NLP P60 protein
BCV67_RS16630	COG0791	NLP P60 protein
BCV67_RS16640	COG2311	Membrane
BCV67_RS16650	COG0697	spore germination
BCV67_RS16670	COG3590	peptidase
BCV67_RS16695	COG0489	protein tyrosine kinase activity
BCV67_RS16700	COG0717	Belongs to the dCTP deaminase family
BCV67_RS16710	COG0412	Dienelactone hydrolase
BCV67_RS16715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCV67_RS16725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV67_RS16740	COG0433	COG0433 Predicted ATPase
BCV67_RS16750	COG0688	phosphatidylethanolamine metabolic process
BCV67_RS16760	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV67_RS16765	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCV67_RS16770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCV67_RS16775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV67_RS16795	COG0135	phosphoribosylanthranilate isomerase activity
BCV67_RS16810	COG2255	four-way junction helicase activity
BCV67_RS16830	COG0133	tryptophan synthase activity
BCV67_RS16840	COG0159	tryptophan synthase activity
BCV67_RS16845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCV67_RS16850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV67_RS16860	COG0149	triose-phosphate isomerase activity
BCV67_RS16875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV67_RS16880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV67_RS16885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV67_RS16890	COG0649	NAD binding
BCV67_RS16895	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCV67_RS16905	COG1034	ATP synthesis coupled electron transport
BCV67_RS16940	COG1007	ATP synthesis coupled electron transport
BCV67_RS16950	COG0779	Required for maturation of 30S ribosomal subunits
BCV67_RS16955	COG0195	Participates in both transcription termination and antitermination
BCV67_RS16960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCV67_RS16965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCV67_RS16975	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCV67_RS16980	COG1185	polyribonucleotide nucleotidyltransferase activity
BCV67_RS17000	COG0848	biopolymer transport protein
BCV67_RS17010	COG1663	tetraacyldisaccharide 4'-kinase activity
BCV67_RS17015	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BCV67_RS17020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV67_RS17030	COG0322	excinuclease ABC activity
BCV67_RS17110	COG2200	EAL domain
BCV67_RS17115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCV67_RS17120	COG0069	glutamate synthase activity
BCV67_RS17145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV67_RS17155	COG1253	flavin adenine dinucleotide binding
BCV67_RS17165	COG0306	phosphate transporter
BCV67_RS17180	COG0504	CTP synthase activity
BCV67_RS17185	COG0148	phosphopyruvate hydratase activity
BCV67_RS17190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCV67_RS17195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCV67_RS17210	COG2840	Smr protein MutS2
BCV67_RS17215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCV67_RS17225	COG1238	metal cluster binding
BCV67_RS17240	COG1534	Rna-binding protein
BCV67_RS17245	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BCV67_RS17250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV67_RS17260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCV67_RS17265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCV67_RS17275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV67_RS17280	COG1546	Belongs to the CinA family
BCV67_RS17285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCV67_RS17290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV67_RS17295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCV67_RS17300	COG2137	regulation of response to DNA damage stimulus
BCV67_RS17305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV67_RS17310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCV67_RS17335	COG0351	phosphomethylpyrimidine kinase
BCV67_RS17350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCV67_RS17355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV67_RS17365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCV67_RS17375	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BCV67_RS17385	COG0617	tRNA 3'-terminal CCA addition
BCV67_RS17395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCV67_RS17400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCV67_RS17405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCV67_RS17410	COG0166	Belongs to the GPI family
BCV67_RS17415	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BCV67_RS17425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCV67_RS17430	COG0671	phosphoesterase, PA-phosphatase related
BCV67_RS17440	COG1530	ribonuclease E activity
BCV67_RS17450	COG0428	transporter
BCV67_RS17460	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCV67_RS17465	COG0316	Belongs to the HesB IscA family
BCV67_RS17465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCV67_RS17495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS17505	COG1247	-acetyltransferase
BCV67_RS17510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV67_RS17515	COG2957	Belongs to the agmatine deiminase family
BCV67_RS17530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCV67_RS17540	COG0776	regulation of translation
BCV67_RS17550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV67_RS17555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV67_RS17570	COG0183	Belongs to the thiolase family
BCV67_RS17575	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV67_RS17575	COG1024	Enoyl-CoA hydratase
BCV67_RS17590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCV67_RS17600	COG1426	Protein conserved in bacteria
BCV67_RS17605	COG2976	Protein conserved in bacteria
BCV67_RS17610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV67_RS17615	COG1160	GTP binding
BCV67_RS17620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV67_RS17625	COG0475	glutathione-regulated potassium exporter activity
BCV67_RS17625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV67_RS17630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCV67_RS17640	COG0519	Catalyzes the synthesis of GMP from XMP
BCV67_RS17640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV67_RS17650	COG3188	usher protein
BCV67_RS17655	COG3121	Chaperone
BCV67_RS17660	COG3539	Fimbrial protein
BCV67_RS17665	COG0583	DNA-binding transcription factor activity
BCV67_RS17675	COG1346	cytolysis
BCV67_RS17680	COG0697	spore germination
BCV67_RS17690	COG0167	dihydroorotate dehydrogenase activity
BCV67_RS17705	COG1012	belongs to the aldehyde dehydrogenase family
BCV67_RS17710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCV67_RS17715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCV67_RS17760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV67_RS17770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV67_RS17830	COG1192	Involved in chromosome partitioning
BCV67_RS17945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV67_RS18015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCV67_RS18020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV67_RS18025	COG0124	histidyl-tRNA synthetase
BCV67_RS18035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCV67_RS18040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCV67_RS18045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCV67_RS18050	COG0131	Imidazoleglycerol-phosphate dehydratase
BCV67_RS18050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV67_RS18055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCV67_RS18060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCV67_RS18070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCV67_RS18070	COG0140	phosphoribosyl-ATP diphosphatase activity
BCV67_RS18080	COG0318	PFAM AMP-dependent synthetase and ligase
BCV67_RS18090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV67_RS18115	COG2274	protein secretion by the type I secretion system
BCV67_RS18145	COG0840	transmembrane signaling receptor activity
BCV67_RS18150	COG0840	transmembrane signaling receptor activity
BCV67_RS18160	COG0835	chemotaxis
BCV67_RS18165	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCV67_RS18170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV67_RS18180	COG0840	transmembrane signaling receptor activity
BCV67_RS18185	COG0840	transmembrane signaling receptor activity
BCV67_RS18190	COG0840	transmembrane signaling receptor activity
BCV67_RS18200	COG0745	RESPONSE REGULATOR receiver
BCV67_RS18210	COG0835	chemotaxis
BCV67_RS18225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCV67_RS18230	COG0643	Histidine kinase
BCV67_RS18230	COG0784	Response regulator, receiver
BCV67_RS18230	COG2198	Histidine kinase
BCV67_RS18260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV67_RS18265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV67_RS18290	COG1793	dna ligase
BCV67_RS18295	COG1201	RNA secondary structure unwinding
BCV67_RS18305	COG0531	amino acid
BCV67_RS18315	COG1408	metallophosphoesterase
BCV67_RS18320	COG1285	pathogenesis
BCV67_RS18325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BCV67_RS18330	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCV67_RS18335	COG0235	Class ii aldolase
BCV67_RS18340	COG0531	amino acid
BCV67_RS18345	COG0531	amino acid
BCV67_RS18355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV67_RS18360	COG0277	FAD linked oxidase domain protein
BCV67_RS18365	COG5002	protein histidine kinase activity
BCV67_RS18370	COG0745	RESPONSE REGULATOR receiver
BCV67_RS18380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV67_RS18400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCV67_RS18420	COG1024	Enoyl-CoA hydratase
BCV67_RS18445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCV67_RS18450	COG0505	Belongs to the CarA family
BCV67_RS18460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCV67_RS18465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV67_RS18475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV67_RS18490	COG3209	COG3209 Rhs family protein
BCV67_RS18500	COG2963	transposase activity
BCV67_RS18505	COG2801	Transposase and inactivated derivatives
BCV67_RS18635	COG2885	chlorophyll binding
BCV67_RS18645	COG2259	Doxx family
BCV67_RS18650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCV67_RS18665	COG2986	histidine ammonia-lyase
BCV67_RS18670	COG1228	amidohydrolase
BCV67_RS18690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV67_RS18710	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCV67_RS18715	COG0077	Prephenate dehydratase
BCV67_RS18715	COG1605	Chorismate mutase
BCV67_RS18720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCV67_RS18735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCV67_RS18740	COG0583	DNA-binding transcription factor activity
BCV67_RS18780	COG0305	Participates in initiation and elongation during chromosome replication
BCV67_RS18785	COG0415	Belongs to the DNA photolyase family
BCV67_RS18795	COG3706	GGDEF domain
BCV67_RS18800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV67_RS18815	COG0587	DNA-directed DNA polymerase activity
BCV67_RS18825	COG3190	flagellar
BCV67_RS18875	COG1677	Flagellar hook-basal body complex protein FliE
BCV67_RS18880	COG0438	transferase activity, transferring glycosyl groups
BCV67_RS18880	COG1216	Glycosyl transferase, family 2
BCV67_RS18885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCV67_RS18895	COG1215	transferase activity, transferring glycosyl groups
BCV67_RS18905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCV67_RS18905	COG0463	Glycosyl transferase, family 2
BCV67_RS18910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BCV67_RS18915	COG0110	maltose O-acetyltransferase activity
BCV67_RS18925	COG2201	protein-glutamate methylesterase activity
BCV67_RS18930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCV67_RS18960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV67_RS18985	COG1706	bacterial-type flagellum-dependent cell motility
BCV67_RS18990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BCV67_RS19000	COG4787	bacterial-type flagellum-dependent cell motility
BCV67_RS19010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCV67_RS19015	COG1558	bacterial-type flagellum-dependent cell motility
BCV67_RS19025	COG0835	chemotaxis
BCV67_RS19025	COG0784	Response regulator, receiver
BCV67_RS19045	COG5002	protein histidine kinase activity
BCV67_RS19075	COG2915	High frequency lysogenization protein hflD homolog
BCV67_RS19080	COG0482	sulfurtransferase activity
BCV67_RS19100	COG0542	response to heat
BCV67_RS19125	COG0492	ferredoxin-NADP+ reductase activity
BCV67_RS19130	COG1674	ftsk spoiiie
BCV67_RS19135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCV67_RS19140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV67_RS19145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCV67_RS19150	COG0837	glucose binding
BCV67_RS19155	COG1446	asparaginase
BCV67_RS19160	COG3142	Participates in the control of copper homeostasis
BCV67_RS19240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV67_RS19245	COG0668	transmembrane transport
BCV67_RS19250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV67_RS19270	COG2183	response to ionizing radiation
BCV67_RS19275	COG1704	LemA family
BCV67_RS19295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV67_RS19300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV67_RS19335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid