locus-tag	class	description
ICJ04_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICJ04_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICJ04_RS00020	COG0187	DNA topoisomerase II activity
ICJ04_RS00025	COG1266	CAAX protease self-immunity
ICJ04_RS00030	COG0501	Belongs to the peptidase M48B family
ICJ04_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ04_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ICJ04_RS00100	COG4772	TonB-dependent receptor
ICJ04_RS00135	COG0800	Aldolase
ICJ04_RS00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ04_RS00170	COG2755	lipolytic protein G-D-S-L family
ICJ04_RS00175	COG2272	Belongs to the type-B carboxylesterase lipase family
ICJ04_RS00180	COG2755	lipolytic protein G-D-S-L family
ICJ04_RS00180	COG0657	acetylesterase activity
ICJ04_RS00190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ICJ04_RS00205	COG3507	Belongs to the glycosyl hydrolase 43 family
ICJ04_RS00210	COG1609	Transcriptional regulator
ICJ04_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS00225	COG2755	lipolytic protein G-D-S-L family
ICJ04_RS00230	COG3186	Phenylalanine-4-hydroxylase
ICJ04_RS00235	COG1522	sequence-specific DNA binding
ICJ04_RS00260	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICJ04_RS00270	COG4771	TonB-dependent receptor
ICJ04_RS00280	COG1119	ATPase activity
ICJ04_RS00290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICJ04_RS00300	COG2815	serine threonine protein kinase
ICJ04_RS00300	COG0515	serine threonine protein kinase
ICJ04_RS00305	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ICJ04_RS00310	COG1435	thymidine kinase activity
ICJ04_RS00330	COG3132	Protein of unknown function, DUF480
ICJ04_RS00335	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ICJ04_RS00340	COG0284	orotidine-5'-phosphate decarboxylase activity
ICJ04_RS00350	COG5640	endopeptidase activity
ICJ04_RS00360	COG2937	Belongs to the GPAT DAPAT family
ICJ04_RS00370	COG0037	tRNA processing
ICJ04_RS00375	COG2974	May be involved in recombination
ICJ04_RS00385	COG1803	Methylglyoxal synthase
ICJ04_RS00395	COG0493	'glutamate synthase
ICJ04_RS00400	COG0069	glutamate synthase activity
ICJ04_RS00400	COG0067	glutamate synthase
ICJ04_RS00400	COG0070	glutamate synthase
ICJ04_RS00420	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS00460	COG1111	helicase
ICJ04_RS00460	COG1205	dead DEAH box helicase
ICJ04_RS00490	COG0714	Associated with various cellular activities
ICJ04_RS00510	COG0312	modulator of DNA gyrase
ICJ04_RS00520	COG3550	peptidyl-serine autophosphorylation
ICJ04_RS00525	COG1396	sequence-specific DNA binding
ICJ04_RS00540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICJ04_RS00560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ04_RS00565	COG2050	protein possibly involved in aromatic compounds catabolism
ICJ04_RS00595	COG1968	undecaprenyl-diphosphatase activity
ICJ04_RS00600	COG0174	glutamine synthetase
ICJ04_RS00605	COG0347	Belongs to the P(II) protein family
ICJ04_RS00610	COG0004	ammonium transporteR
ICJ04_RS00625	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ICJ04_RS00635	COG3852	Histidine kinase
ICJ04_RS00645	COG2032	superoxide dismutase activity
ICJ04_RS00650	COG2032	superoxide dismutase activity
ICJ04_RS00660	COG0183	Belongs to the thiolase family
ICJ04_RS00690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICJ04_RS00695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ICJ04_RS00700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ICJ04_RS00720	COG2831	hemolysin activation secretion protein
ICJ04_RS00725	COG3210	domain, Protein
ICJ04_RS00725	COG3210	domain, Protein
ICJ04_RS00775	COG4251	negative regulation of phosphorylation
ICJ04_RS00775	COG3706	GGDEF domain
ICJ04_RS00775	COG2203	Gaf domain
ICJ04_RS00775	COG5001	Diguanylate cyclase
ICJ04_RS00815	COG2197	response regulator
ICJ04_RS00840	COG2205	protein histidine kinase activity
ICJ04_RS00840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ04_RS00845	COG2197	response regulator
ICJ04_RS00850	COG2197	response regulator
ICJ04_RS00905	COG2197	response regulator
ICJ04_RS00910	COG2205	protein histidine kinase activity
ICJ04_RS00910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ04_RS00915	COG3474	cytochrome
ICJ04_RS00935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ICJ04_RS00945	COG0612	Peptidase, M16
ICJ04_RS00965	COG0339	signal peptide processing
ICJ04_RS00975	COG0681	Belongs to the peptidase S26 family
ICJ04_RS00980	COG2814	Major facilitator Superfamily
ICJ04_RS00985	COG0583	DNA-binding transcription factor activity
ICJ04_RS00990	COG0583	DNA-binding transcription factor activity
ICJ04_RS00995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICJ04_RS01000	COG2224	Isocitrate lyase
ICJ04_RS01030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ICJ04_RS01035	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS01045	COG3245	cytochrome
ICJ04_RS01055	COG0697	spore germination
ICJ04_RS01065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICJ04_RS01075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ04_RS01085	COG1607	acyl-coa hydrolase
ICJ04_RS01090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ICJ04_RS01095	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS01120	COG1335	isochorismatase
ICJ04_RS01125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICJ04_RS01150	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ICJ04_RS01160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICJ04_RS01185	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICJ04_RS01190	COG3800	Transcriptional regulator
ICJ04_RS01190	COG1396	sequence-specific DNA binding
ICJ04_RS01200	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS01205	COG1024	Enoyl-CoA hydratase
ICJ04_RS01210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICJ04_RS01225	COG1764	response to oxidative stress
ICJ04_RS01240	COG0659	secondary active sulfate transmembrane transporter activity
ICJ04_RS01255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICJ04_RS01275	COG3228	Belongs to the MtfA family
ICJ04_RS01285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ICJ04_RS01285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ICJ04_RS01290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICJ04_RS01340	COG3237	CsbD-like
ICJ04_RS01350	COG0180	Tryptophanyl-tRNA synthetase
ICJ04_RS01375	COG0697	spore germination
ICJ04_RS01390	COG0577	efflux transmembrane transporter activity
ICJ04_RS01390	COG1136	(ABC) transporter
ICJ04_RS01400	COG1136	(ABC) transporter
ICJ04_RS01410	COG1131	(ABC) transporter
ICJ04_RS01420	COG4585	Histidine kinase
ICJ04_RS01425	COG2197	response regulator
ICJ04_RS01435	COG0753	catalase activity
ICJ04_RS01440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICJ04_RS01470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICJ04_RS01485	COG5507	3-demethylubiquinone-9 3-methyltransferase
ICJ04_RS01505	COG4807	Protein conserved in bacteria
ICJ04_RS01515	COG4221	oxidoreductase activity
ICJ04_RS01525	COG0018	arginyl-trna synthetase
ICJ04_RS01530	COG2003	Belongs to the UPF0758 family
ICJ04_RS01535	COG2197	response regulator
ICJ04_RS01540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICJ04_RS01545	COG0756	dUTP diphosphatase activity
ICJ04_RS01560	COG2205	protein histidine kinase activity
ICJ04_RS01570	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ICJ04_RS01575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ICJ04_RS01590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICJ04_RS01595	COG0708	Exodeoxyribonuclease III
ICJ04_RS01600	COG2211	Major facilitator Superfamily
ICJ04_RS01615	COG0739	heme binding
ICJ04_RS01620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICJ04_RS01665	COG4942	peptidase
ICJ04_RS01670	COG0793	Belongs to the peptidase S41A family
ICJ04_RS01695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICJ04_RS01700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICJ04_RS01705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ICJ04_RS01730	COG1612	heme a metabolic process
ICJ04_RS01735	COG0109	protoheme IX farnesyltransferase activity
ICJ04_RS01755	COG0358	DNA primase activity
ICJ04_RS01760	COG1295	ribonuclease BN
ICJ04_RS01765	COG1610	YqeY-like protein
ICJ04_RS01775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICJ04_RS01780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICJ04_RS01785	COG0668	transmembrane transport
ICJ04_RS01800	COG2133	pyrroloquinoline quinone binding
ICJ04_RS01810	COG0531	amino acid
ICJ04_RS01820	COG1737	Transcriptional regulator
ICJ04_RS01825	COG4948	Mandelate Racemase Muconate Lactonizing
ICJ04_RS01875	COG5383	Protein conserved in bacteria
ICJ04_RS01890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICJ04_RS01895	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICJ04_RS01920	COG0778	Nitroreductase
ICJ04_RS01925	COG2353	YceI-like domain
ICJ04_RS01935	COG2375	cellular response to nickel ion
ICJ04_RS01950	COG2770	Histidine kinase
ICJ04_RS01950	COG2208	phosphoserine phosphatase activity
ICJ04_RS02065	COG0210	DNA helicase
ICJ04_RS02070	COG2267	carboxylic ester hydrolase activity
ICJ04_RS02110	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ICJ04_RS02115	COG0741	lytic transglycosylase activity
ICJ04_RS02135	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ICJ04_RS02140	COG4941	Belongs to the sigma-70 factor family
ICJ04_RS02150	COG3275	phosphorelay sensor kinase activity
ICJ04_RS02155	COG3279	Response regulator of the LytR AlgR family
ICJ04_RS02175	COG3590	peptidase
ICJ04_RS02180	COG5001	Diguanylate cyclase
ICJ04_RS02185	COG3384	dioxygenase
ICJ04_RS02190	COG0025	NhaP-type Na H and K H
ICJ04_RS02245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ04_RS02260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ04_RS02260	COG2205	protein histidine kinase activity
ICJ04_RS02280	COG1187	pseudouridine synthase activity
ICJ04_RS02285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ04_RS02295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICJ04_RS02300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICJ04_RS02310	COG0583	DNA-binding transcription factor activity
ICJ04_RS02335	COG1956	GAF domain-containing protein
ICJ04_RS02340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ04_RS02345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICJ04_RS02360	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS02365	COG5002	protein histidine kinase activity
ICJ04_RS02370	COG0720	synthase
ICJ04_RS02375	COG4206	TonB-dependent receptor
ICJ04_RS02395	COG1629	transport
ICJ04_RS02395	COG4771	TonB-dependent receptor
ICJ04_RS02400	COG0513	Belongs to the DEAD box helicase family
ICJ04_RS02410	COG0625	glutathione transferase activity
ICJ04_RS02440	COG0626	cystathionine gamma-synthase activity
ICJ04_RS02465	COG0110	maltose O-acetyltransferase activity
ICJ04_RS02470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICJ04_RS02490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ICJ04_RS02515	COG0463	Glycosyl transferase, family 2
ICJ04_RS02530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICJ04_RS02605	COG1127	ABC transporter
ICJ04_RS02610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICJ04_RS02625	COG0442	prolyl-tRNA aminoacylation
ICJ04_RS02635	COG1183	phosphatidylcholine synthase activity
ICJ04_RS02645	COG0456	acetyltransferase
ICJ04_RS02655	COG0525	valine-tRNA ligase activity
ICJ04_RS02665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICJ04_RS02675	COG0795	lipopolysaccharide-transporting ATPase activity
ICJ04_RS02690	COG4974	Belongs to the 'phage' integrase family
ICJ04_RS02700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICJ04_RS02730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICJ04_RS02730	COG0047	phosphoribosylformylglycinamidine synthase activity
ICJ04_RS02735	COG5295	Hep Hag repeat protein
ICJ04_RS02740	COG1404	Belongs to the peptidase S8 family
ICJ04_RS02745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICJ04_RS02750	COG1459	type II secretion system
ICJ04_RS02755	COG2165	general secretion pathway protein
ICJ04_RS02760	COG4970	Tfp pilus assembly protein FimT
ICJ04_RS02765	COG2165	general secretion pathway protein
ICJ04_RS02770	COG4795	General secretion pathway protein
ICJ04_RS02775	COG3156	type II secretion system protein K
ICJ04_RS02780	COG3166	PFAM Fimbrial assembly family protein
ICJ04_RS02795	COG1450	Type ii and iii secretion system protein
ICJ04_RS02810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICJ04_RS02815	COG2252	PERMEase
ICJ04_RS02820	COG0488	(ABC) transporter
ICJ04_RS02835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICJ04_RS02840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICJ04_RS02845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICJ04_RS02845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICJ04_RS02865	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICJ04_RS02870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICJ04_RS02885	COG3121	Chaperone
ICJ04_RS02895	COG3188	usher protein
ICJ04_RS02905	COG0277	FAD linked oxidase domain protein
ICJ04_RS02910	COG0792	nuclease activity
ICJ04_RS02930	COG2001	Belongs to the MraZ family
ICJ04_RS02935	COG0275	rRNA processing
ICJ04_RS02940	COG3116	cell division
ICJ04_RS02950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICJ04_RS02955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICJ04_RS02970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICJ04_RS02975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICJ04_RS02980	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICJ04_RS02985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ICJ04_RS03000	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ICJ04_RS03010	COG0739	heme binding
ICJ04_RS03015	COG0653	protein targeting
ICJ04_RS03025	COG0494	nUDIX hydrolase
ICJ04_RS03035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ICJ04_RS03050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICJ04_RS03055	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ICJ04_RS03070	COG1607	acyl-coa hydrolase
ICJ04_RS03075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICJ04_RS03085	COG4106	trans-aconitate 2-methyltransferase activity
ICJ04_RS03090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICJ04_RS03100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICJ04_RS03105	COG0667	Aldo Keto reductase
ICJ04_RS03130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ICJ04_RS03135	COG4181	ATPase activity
ICJ04_RS03150	COG0642	Histidine kinase
ICJ04_RS03160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ICJ04_RS03165	COG0861	Integral membrane protein TerC family
ICJ04_RS03185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICJ04_RS03200	COG0436	Aminotransferase
ICJ04_RS03210	COG2832	Protein of unknown function (DUF454)
ICJ04_RS03240	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICJ04_RS03270	COG3188	usher protein
ICJ04_RS03280	COG3121	Chaperone
ICJ04_RS03295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS03315	COG2226	methyltransferase
ICJ04_RS03320	COG0308	aminopeptidase N
ICJ04_RS03340	COG0546	phosphoglycolate phosphatase activity
ICJ04_RS03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ04_RS03350	COG1077	Cell shape determining protein MreB Mrl
ICJ04_RS03365	COG0768	penicillin binding
ICJ04_RS03370	COG0772	Belongs to the SEDS family
ICJ04_RS03375	COG2951	lytic endotransglycosylase activity
ICJ04_RS03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICJ04_RS03385	COG1686	Belongs to the peptidase S11 family
ICJ04_RS03395	COG5295	Hep Hag repeat protein
ICJ04_RS03400	COG5295	Hep Hag repeat protein
ICJ04_RS03415	COG2921	Belongs to the UPF0250 family
ICJ04_RS03425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ICJ04_RS03445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ICJ04_RS03450	COG0673	inositol 2-dehydrogenase activity
ICJ04_RS03465	COG4191	Histidine kinase
ICJ04_RS03475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICJ04_RS03500	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ICJ04_RS03510	COG0837	glucose binding
ICJ04_RS03520	COG1609	Transcriptional regulator
ICJ04_RS03525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICJ04_RS03530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICJ04_RS03550	COG0617	tRNA 3'-terminal CCA addition
ICJ04_RS03565	COG4773	Receptor
ICJ04_RS03575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICJ04_RS03590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ICJ04_RS03595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ICJ04_RS03610	COG1064	alcohol dehydrogenase
ICJ04_RS03615	COG0583	DNA-binding transcription factor activity
ICJ04_RS03625	COG3459	Glycosyltransferase 36 associated
ICJ04_RS03655	COG1307	EDD domain protein, DegV family
ICJ04_RS03665	COG1228	amidohydrolase
ICJ04_RS03670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICJ04_RS03680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICJ04_RS03700	COG0436	Aminotransferase
ICJ04_RS03705	COG1162	GTPase activity
ICJ04_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS03725	COG2851	Citrate transporter
ICJ04_RS03755	COG4191	Histidine kinase
ICJ04_RS03765	COG1301	dicarboxylic acid transport
ICJ04_RS03800	COG1560	Kdo2-lipid A biosynthetic process
ICJ04_RS03805	COG1519	Transferase
ICJ04_RS03820	COG2239	Acts as a magnesium transporter
ICJ04_RS03835	COG1538	Outer membrane efflux protein
ICJ04_RS03840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICJ04_RS03855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS03860	COG0473	3-isopropylmalate dehydrogenase activity
ICJ04_RS03875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICJ04_RS03880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICJ04_RS03900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICJ04_RS03905	COG0405	Gamma-glutamyltransferase
ICJ04_RS03910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ICJ04_RS03915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICJ04_RS03925	COG0823	Involved in the tonB-independent uptake of proteins
ICJ04_RS03945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICJ04_RS03965	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ICJ04_RS03980	COG0563	adenylate kinase activity
ICJ04_RS03985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICJ04_RS03995	COG0586	Pfam SNARE associated Golgi protein
ICJ04_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS04025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ04_RS04030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICJ04_RS04040	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ICJ04_RS04045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICJ04_RS04050	COG0352	thiamine-phosphate diphosphorylase activity
ICJ04_RS04055	COG1773	rubredoxin
ICJ04_RS04060	COG2912	Transglutaminase-like superfamily
ICJ04_RS04070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICJ04_RS04080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICJ04_RS04105	COG0006	proline dipeptidase activity
ICJ04_RS04110	COG0006	proline dipeptidase activity
ICJ04_RS04125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICJ04_RS04135	COG0346	lactoylglutathione lyase activity
ICJ04_RS04140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICJ04_RS04145	COG1561	YicC-like family, N-terminal region
ICJ04_RS04155	COG1758	RNA polymerase activity
ICJ04_RS04160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICJ04_RS04170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICJ04_RS04180	COG0254	rRNA binding
ICJ04_RS04190	COG2205	protein histidine kinase activity
ICJ04_RS04195	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS04205	COG0367	asparagine synthase
ICJ04_RS04235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ICJ04_RS04270	COG0714	Associated with various cellular activities
ICJ04_RS04290	COG2304	oxidoreductase activity
ICJ04_RS04300	COG1301	dicarboxylic acid transport
ICJ04_RS04305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICJ04_RS04315	COG0427	acetyl-CoA hydrolase
ICJ04_RS04335	COG3453	Protein conserved in bacteria
ICJ04_RS04335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ04_RS04345	COG1794	racemase activity, acting on amino acids and derivatives
ICJ04_RS04350	COG3047	cAMP biosynthetic process
ICJ04_RS04355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICJ04_RS04375	COG0126	phosphoglycerate kinase activity
ICJ04_RS04385	COG0469	pyruvate kinase activity
ICJ04_RS04390	COG3588	fructose-bisphosphate aldolase
ICJ04_RS04400	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ICJ04_RS04410	COG0583	DNA-binding transcription factor activity
ICJ04_RS04415	COG0154	amidase activity
ICJ04_RS04425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS04430	COG1115	amino acid carrier protein
ICJ04_RS04435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICJ04_RS04445	COG1115	amino acid carrier protein
ICJ04_RS04455	COG1970	mechanosensitive ion channel activity
ICJ04_RS04475	COG0471	metal ion transport
ICJ04_RS04475	COG3273	potassium ion transport
ICJ04_RS04480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ICJ04_RS04485	COG2022	thiamine diphosphate biosynthetic process
ICJ04_RS04510	COG2205	protein histidine kinase activity
ICJ04_RS04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ04_RS04515	COG0189	ligase activity
ICJ04_RS04525	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS04530	COG2205	protein histidine kinase activity
ICJ04_RS04550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ICJ04_RS04560	COG4969	Belongs to the N-Me-Phe pilin family
ICJ04_RS04580	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ04_RS04585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ICJ04_RS04590	COG1678	Uncharacterized ACR, COG1678
ICJ04_RS04595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICJ04_RS04600	COG0540	Belongs to the ATCase OTCase family
ICJ04_RS04620	COG2239	Acts as a magnesium transporter
ICJ04_RS04625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICJ04_RS04640	COG1660	Displays ATPase and GTPase activities
ICJ04_RS04645	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICJ04_RS04650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICJ04_RS04655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICJ04_RS04665	COG1137	ATPase activity
ICJ04_RS04680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ICJ04_RS04695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICJ04_RS04715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICJ04_RS04730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ICJ04_RS04740	COG0628	permease
ICJ04_RS04750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICJ04_RS04755	COG3178	'Phosphotransferase
ICJ04_RS04760	COG2261	transglycosylase associated protein
ICJ04_RS04795	COG1477	protein flavinylation
ICJ04_RS04815	COG4771	TonB-dependent receptor
ICJ04_RS04825	COG3128	pkhd-type hydroxylase
ICJ04_RS04845	COG2146	nitrite reductase [NAD(P)H] activity
ICJ04_RS04855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICJ04_RS04860	COG0719	Fe-S assembly protein
ICJ04_RS04865	COG0396	ATPase activity
ICJ04_RS04870	COG3755	Protein conserved in bacteria
ICJ04_RS04875	COG0719	Fe-S assembly protein
ICJ04_RS04880	COG1959	2 iron, 2 sulfur cluster binding
ICJ04_RS04890	COG0693	protein deglycase activity
ICJ04_RS04915	COG1764	response to oxidative stress
ICJ04_RS04920	COG0384	phenazine biosynthesis protein PhzF
ICJ04_RS04925	COG0384	phenazine biosynthesis protein PhzF
ICJ04_RS04930	COG0527	aspartate kinase activity
ICJ04_RS04940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICJ04_RS04945	COG0142	geranyltranstransferase activity
ICJ04_RS04950	COG0366	Alpha amylase catalytic
ICJ04_RS04960	COG1082	Xylose isomerase domain protein TIM barrel
ICJ04_RS04970	COG2190	(PTS) system
ICJ04_RS04970	COG2211	Major facilitator Superfamily
ICJ04_RS04975	COG0366	Alpha amylase catalytic
ICJ04_RS04975	COG1874	Beta-galactosidase
ICJ04_RS04995	COG1609	Transcriptional regulator
ICJ04_RS05000	COG0629	single-stranded DNA binding
ICJ04_RS05035	COG0673	inositol 2-dehydrogenase activity
ICJ04_RS05040	COG2211	Major facilitator Superfamily
ICJ04_RS05050	COG1609	Transcriptional regulator
ICJ04_RS05055	COG2017	converts alpha-aldose to the beta-anomer
ICJ04_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS05065	COG0800	Aldolase
ICJ04_RS05070	COG4948	Mandelate Racemase Muconate Lactonizing
ICJ04_RS05080	COG3734	2-keto-3-deoxy-galactonokinase
ICJ04_RS05090	COG3345	alpha-galactosidase
ICJ04_RS05095	COG2186	Transcriptional regulator
ICJ04_RS05100	COG2258	MOSC domain
ICJ04_RS05115	COG1408	metallophosphoesterase
ICJ04_RS05130	COG4773	Receptor
ICJ04_RS05135	COG0579	oxidoreductase
ICJ04_RS05155	COG3104	oligopeptide transport
ICJ04_RS05165	COG1297	OPT oligopeptide transporter protein
ICJ04_RS05170	COG1506	peptidase
ICJ04_RS05170	COG0823	Involved in the tonB-independent uptake of proteins
ICJ04_RS05185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ICJ04_RS05190	COG2894	cell division
ICJ04_RS05205	COG4585	Histidine kinase
ICJ04_RS05210	COG2197	response regulator
ICJ04_RS05235	COG1073	alpha beta
ICJ04_RS05255	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICJ04_RS05265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ICJ04_RS05275	COG1595	DNA-templated transcription, initiation
ICJ04_RS05285	COG1946	Acyl-CoA thioesterase
ICJ04_RS05300	COG0824	Thioesterase
ICJ04_RS05305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICJ04_RS05310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ICJ04_RS05315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ICJ04_RS05320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICJ04_RS05325	COG0268	Binds directly to 16S ribosomal RNA
ICJ04_RS05330	COG0728	peptidoglycan biosynthetic process
ICJ04_RS05335	COG0196	riboflavin kinase activity
ICJ04_RS05340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICJ04_RS05350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICJ04_RS05395	COG2801	Transposase and inactivated derivatives
ICJ04_RS05510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ04_RS05515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICJ04_RS05520	COG1620	l-lactate permease
ICJ04_RS05535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICJ04_RS05540	COG1845	cytochrome c oxidase, subunit III
ICJ04_RS05545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ICJ04_RS05565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICJ04_RS05575	COG0228	four-way junction DNA binding
ICJ04_RS05580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICJ04_RS05585	COG0336	Belongs to the RNA methyltransferase TrmD family
ICJ04_RS05590	COG0335	large ribosomal subunit rRNA binding
ICJ04_RS05600	COG0534	Mate efflux family protein
ICJ04_RS05610	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ICJ04_RS05620	COG2755	lipolytic protein G-D-S-L family
ICJ04_RS05620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ICJ04_RS05635	COG2200	EAL domain
ICJ04_RS05695	COG2351	hydroxyisourate hydrolase activity
ICJ04_RS05710	COG0588	phosphoglycerate mutase activity
ICJ04_RS05720	COG3590	peptidase
ICJ04_RS05730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICJ04_RS05740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ICJ04_RS05745	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS05750	COG2205	protein histidine kinase activity
ICJ04_RS05755	COG4452	Inner membrane protein CreD
ICJ04_RS05765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICJ04_RS05770	COG0735	belongs to the Fur family
ICJ04_RS05805	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICJ04_RS05805	COG1024	Enoyl-CoA hydratase
ICJ04_RS05820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICJ04_RS05825	COG0481	GTPase activity
ICJ04_RS05830	COG0681	Belongs to the peptidase S26 family
ICJ04_RS05845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICJ04_RS05850	COG1381	Involved in DNA repair and RecF pathway recombination
ICJ04_RS05865	COG2954	triphosphatase activity
ICJ04_RS05870	COG1472	Belongs to the glycosyl hydrolase 3 family
ICJ04_RS05875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICJ04_RS05880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICJ04_RS05885	COG1278	Cold shock
ICJ04_RS05905	COG1201	RNA secondary structure unwinding
ICJ04_RS05910	COG1793	dna ligase
ICJ04_RS05920	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS05935	COG0183	Belongs to the thiolase family
ICJ04_RS05955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ04_RS05965	COG1451	nucleotide metabolic process
ICJ04_RS05975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ICJ04_RS06015	COG1077	Cell shape determining protein MreB Mrl
ICJ04_RS06020	COG2824	Alkylphosphonate utilization operon protein PhnA
ICJ04_RS06050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICJ04_RS06050	COG0392	lysyltransferase activity
ICJ04_RS06055	COG0251	oxidation-reduction process
ICJ04_RS06060	COG2878	Part of a membrane complex involved in electron transport
ICJ04_RS06070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICJ04_RS06070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICJ04_RS06080	COG0346	lactoylglutathione lyase activity
ICJ04_RS06100	COG3485	protocatechuate 3,4-dioxygenase
ICJ04_RS06120	COG3118	belongs to the thioredoxin family
ICJ04_RS06135	COG0495	leucyl-tRNA aminoacylation
ICJ04_RS06150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICJ04_RS06160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICJ04_RS06180	COG4771	TonB-dependent receptor
ICJ04_RS06190	COG2968	Membrane
ICJ04_RS06195	COG0424	maF-like protein
ICJ04_RS06210	COG0312	modulator of DNA gyrase
ICJ04_RS06215	COG3028	Belongs to the UPF0307 family
ICJ04_RS06220	COG0312	modulator of DNA gyrase
ICJ04_RS06255	COG3279	Response regulator of the LytR AlgR family
ICJ04_RS06260	COG3275	phosphorelay sensor kinase activity
ICJ04_RS06270	COG0142	geranyltranstransferase activity
ICJ04_RS06275	COG1722	exodeoxyribonuclease VII activity
ICJ04_RS06290	COG0514	ATP-dependent DNA helicase (RecQ)
ICJ04_RS06300	COG1301	dicarboxylic acid transport
ICJ04_RS06335	COG2204	response regulator
ICJ04_RS06340	COG0791	NLP P60 protein
ICJ04_RS06345	COG0791	NLP P60 protein
ICJ04_RS06355	COG2311	Membrane
ICJ04_RS06365	COG0697	spore germination
ICJ04_RS06390	COG3590	peptidase
ICJ04_RS06405	COG0489	protein tyrosine kinase activity
ICJ04_RS06410	COG0717	Belongs to the dCTP deaminase family
ICJ04_RS06425	COG0412	Dienelactone hydrolase
ICJ04_RS06435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICJ04_RS06445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ04_RS06450	COG0433	COG0433 Predicted ATPase
ICJ04_RS06465	COG2166	iron-sulfur cluster assembly
ICJ04_RS06485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICJ04_RS06490	COG0137	argininosuccinate synthase activity
ICJ04_RS06495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICJ04_RS06500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICJ04_RS06510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICJ04_RS06515	COG0165	Argininosuccinate lyase
ICJ04_RS06525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICJ04_RS06535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICJ04_RS06545	COG1215	transferase activity, transferring glycosyl groups
ICJ04_RS06550	COG1649	PFAM Uncharacterised BCR, COG1649
ICJ04_RS06550	COG0726	polysaccharide deacetylase
ICJ04_RS06580	COG1294	oxidase, subunit
ICJ04_RS06590	COG4988	ABC transporter
ICJ04_RS06595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICJ04_RS06605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ04_RS06610	COG0688	phosphatidylethanolamine metabolic process
ICJ04_RS06615	COG1999	signal sequence binding
ICJ04_RS06620	COG2890	protein-(glutamine-N5) methyltransferase activity
ICJ04_RS06625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICJ04_RS06630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICJ04_RS06635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICJ04_RS06650	COG0101	tRNA pseudouridine synthase activity
ICJ04_RS06655	COG0135	phosphoribosylanthranilate isomerase activity
ICJ04_RS06665	COG0133	tryptophan synthase activity
ICJ04_RS06670	COG0159	tryptophan synthase activity
ICJ04_RS06675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICJ04_RS06680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICJ04_RS06685	COG3119	arylsulfatase activity
ICJ04_RS06695	COG0149	triose-phosphate isomerase activity
ICJ04_RS06710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ04_RS06715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ04_RS06720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ04_RS06725	COG0649	NAD binding
ICJ04_RS06730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ICJ04_RS06735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ICJ04_RS06745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ICJ04_RS06750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ04_RS06775	COG1007	ATP synthesis coupled electron transport
ICJ04_RS06790	COG0779	Required for maturation of 30S ribosomal subunits
ICJ04_RS06795	COG0195	Participates in both transcription termination and antitermination
ICJ04_RS06800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICJ04_RS06805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICJ04_RS06815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICJ04_RS06845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICJ04_RS06850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICJ04_RS06865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICJ04_RS06895	COG0477	Major facilitator Superfamily
ICJ04_RS06925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICJ04_RS06935	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS06945	COG3040	lipid binding
ICJ04_RS06950	COG0024	Methionine aminopeptidase
ICJ04_RS06965	COG2130	NADP-dependent
ICJ04_RS06985	COG0840	transmembrane signaling receptor activity
ICJ04_RS06990	COG4771	TonB-dependent receptor
ICJ04_RS07010	COG1570	exodeoxyribonuclease VII activity
ICJ04_RS07015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICJ04_RS07020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICJ04_RS07020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICJ04_RS07030	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICJ04_RS07035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICJ04_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS07065	COG0501	Belongs to the peptidase M48B family
ICJ04_RS07075	COG0483	inositol monophosphate 1-phosphatase activity
ICJ04_RS07095	COG1509	lysine 2,3-aminomutase activity
ICJ04_RS07100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICJ04_RS07105	COG0402	S-adenosylhomocysteine deaminase activity
ICJ04_RS07110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICJ04_RS07130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICJ04_RS07190	COG0436	Aminotransferase
ICJ04_RS07205	COG1187	pseudouridine synthase activity
ICJ04_RS07210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICJ04_RS07215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICJ04_RS07220	COG2350	Protein conserved in bacteria
ICJ04_RS07230	COG1609	Transcriptional regulator
ICJ04_RS07255	COG0395	ABC-type sugar transport system, permease component
ICJ04_RS07270	COG1530	ribonuclease E activity
ICJ04_RS07280	COG0428	transporter
ICJ04_RS07290	COG2154	pterin-4-alpha-carbinolamine dehydratase
ICJ04_RS07295	COG0316	Belongs to the HesB IscA family
ICJ04_RS07295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ICJ04_RS07315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICJ04_RS07325	COG3104	oligopeptide transport
ICJ04_RS07350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICJ04_RS07355	COG0339	signal peptide processing
ICJ04_RS07360	COG0386	Belongs to the glutathione peroxidase family
ICJ04_RS07375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ04_RS07390	COG1393	Belongs to the ArsC family
ICJ04_RS07400	COG2839	Protein conserved in bacteria
ICJ04_RS07415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICJ04_RS07420	COG0084	hydrolase, TatD family'
ICJ04_RS07450	COG0305	Participates in initiation and elongation during chromosome replication
ICJ04_RS07470	COG0567	Dehydrogenase, E1 component
ICJ04_RS07480	COG2850	peptidyl-arginine hydroxylation
ICJ04_RS07515	COG1131	(ABC) transporter
ICJ04_RS07520	COG1725	Transcriptional regulator
ICJ04_RS07525	COG0386	Belongs to the glutathione peroxidase family
ICJ04_RS07535	COG2900	Belongs to the SlyX family
ICJ04_RS07545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ICJ04_RS07565	COG1943	Transposase
ICJ04_RS07570	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS07580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS07595	COG2902	Dehydrogenase
ICJ04_RS07615	COG0667	Aldo Keto reductase
ICJ04_RS07625	COG2925	Exonuclease
ICJ04_RS07630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICJ04_RS07635	COG3844	kynureninase activity
ICJ04_RS07650	COG0288	reversible hydration of carbon dioxide
ICJ04_RS07655	COG2808	Putative FMN-binding domain
ICJ04_RS07675	COG0316	Belongs to the HesB IscA family
ICJ04_RS07680	COG2814	Major facilitator Superfamily
ICJ04_RS07690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICJ04_RS07695	COG0359	binds to the 23S rRNA
ICJ04_RS07710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICJ04_RS07720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ICJ04_RS07730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICJ04_RS07755	COG2223	nitrite transmembrane transporter activity
ICJ04_RS07760	COG2207	Transcriptional regulator
ICJ04_RS07770	COG4221	oxidoreductase activity
ICJ04_RS07800	COG2222	sugar isomerase
ICJ04_RS07805	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
ICJ04_RS07825	COG1349	DNA-binding transcription factor activity
ICJ04_RS07855	COG3920	Histidine kinase
ICJ04_RS07865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICJ04_RS07880	COG1228	amidohydrolase
ICJ04_RS07915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICJ04_RS07920	COG1605	Chorismate mutase
ICJ04_RS07920	COG0077	Prephenate dehydratase
ICJ04_RS07925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICJ04_RS07940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICJ04_RS07945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICJ04_RS07950	COG0583	DNA-binding transcription factor activity
ICJ04_RS07960	COG1074	ATP-dependent DNA helicase activity
ICJ04_RS08005	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS08020	COG2202	Pas domain
ICJ04_RS08020	COG2205	protein histidine kinase activity
ICJ04_RS08030	COG4774	siderophore transport
ICJ04_RS08055	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ICJ04_RS08055	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ICJ04_RS08070	COG2207	Transcriptional regulator
ICJ04_RS08080	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS08085	COG0583	DNA-binding transcription factor activity
ICJ04_RS08090	COG2814	Major facilitator Superfamily
ICJ04_RS08105	COG0583	DNA-binding transcription factor activity
ICJ04_RS08110	COG2814	Major facilitator Superfamily
ICJ04_RS08125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS08130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ04_RS08160	COG3685	Protein conserved in bacteria
ICJ04_RS08175	COG1733	regulation of RNA biosynthetic process
ICJ04_RS08195	COG2885	chlorophyll binding
ICJ04_RS08220	COG3736	Type IV secretory pathway, component VirB8
ICJ04_RS08230	COG2948	multi-organism process
ICJ04_RS08350	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ICJ04_RS08370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ICJ04_RS08395	COG3243	poly(R)-hydroxyalkanoic acid synthase
ICJ04_RS08415	COG2183	response to ionizing radiation
ICJ04_RS08420	COG5001	Diguanylate cyclase
ICJ04_RS08420	COG5002	protein histidine kinase activity
ICJ04_RS08420	COG3447	MASE1 domain protein
ICJ04_RS08485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICJ04_RS08500	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS08515	COG1304	FMN binding
ICJ04_RS08520	COG3161	chorismate lyase activity
ICJ04_RS08530	COG0583	DNA-binding transcription factor activity
ICJ04_RS08540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ04_RS08550	COG2205	protein histidine kinase activity
ICJ04_RS08550	COG5002	protein histidine kinase activity
ICJ04_RS08550	COG0784	Response regulator, receiver
ICJ04_RS08555	COG2205	protein histidine kinase activity
ICJ04_RS08555	COG0784	Response regulator, receiver
ICJ04_RS08560	COG2197	response regulator
ICJ04_RS08565	COG2197	response regulator
ICJ04_RS08615	COG4964	Belongs to the GSP D family
ICJ04_RS08665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ICJ04_RS08670	COG0840	transmembrane signaling receptor activity
ICJ04_RS08680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ04_RS08685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ04_RS08695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICJ04_RS08715	COG0837	glucose binding
ICJ04_RS08720	COG1446	asparaginase
ICJ04_RS08735	COG3655	Transcriptional regulator
ICJ04_RS08740	COG1253	flavin adenine dinucleotide binding
ICJ04_RS08745	COG1366	Belongs to the anti-sigma-factor antagonist family
ICJ04_RS08750	COG1366	Belongs to the anti-sigma-factor antagonist family
ICJ04_RS08755	COG2172	sigma factor antagonist activity
ICJ04_RS08770	COG0784	Response regulator, receiver
ICJ04_RS08770	COG4191	Histidine kinase
ICJ04_RS08775	COG1802	Transcriptional regulator
ICJ04_RS08810	COG3052	prosthetic group binding
ICJ04_RS08820	COG2409	Drug exporters of the RND superfamily
ICJ04_RS08825	COG2223	nitrite transmembrane transporter activity
ICJ04_RS08830	COG1349	DNA-binding transcription factor activity
ICJ04_RS08835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICJ04_RS08840	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICJ04_RS08840	COG0315	cyclic pyranopterin monophosphate synthase activity
ICJ04_RS08845	COG0303	'Molybdopterin
ICJ04_RS08860	COG0725	ABC transporter, periplasmic molybdate-binding protein
ICJ04_RS08865	COG4149	molybdate abc transporter
ICJ04_RS08870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ICJ04_RS08875	COG2323	membrane
ICJ04_RS08890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICJ04_RS08895	COG1640	4-alpha-glucanotransferase
ICJ04_RS08915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ICJ04_RS08925	COG2202	Pas domain
ICJ04_RS08925	COG3920	Histidine kinase
ICJ04_RS08950	COG3537	Alpha-1,2-mannosidase
ICJ04_RS08965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICJ04_RS08970	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ICJ04_RS08975	COG2080	2 iron, 2 sulfur cluster binding
ICJ04_RS08995	COG0784	Response regulator, receiver
ICJ04_RS09000	COG4251	negative regulation of phosphorylation
ICJ04_RS09015	COG1238	metal cluster binding
ICJ04_RS09020	COG0708	Exodeoxyribonuclease III
ICJ04_RS09025	COG1573	uracil-dna glycosylase
ICJ04_RS09055	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ICJ04_RS09075	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS09105	COG1309	transcriptional regulator
ICJ04_RS09120	COG2272	Belongs to the type-B carboxylesterase lipase family
ICJ04_RS09155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ICJ04_RS09165	COG1472	Belongs to the glycosyl hydrolase 3 family
ICJ04_RS09175	COG3387	PFAM Glycoside hydrolase 15-related
ICJ04_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS09210	COG4771	TonB-dependent receptor
ICJ04_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS09265	COG1309	transcriptional regulator
ICJ04_RS09320	COG0028	Belongs to the TPP enzyme family
ICJ04_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
ICJ04_RS09340	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS09350	COG1609	Transcriptional regulator
ICJ04_RS09375	COG1070	Carbohydrate kinase
ICJ04_RS09385	COG0477	Major facilitator Superfamily
ICJ04_RS09390	COG1472	Belongs to the glycosyl hydrolase 3 family
ICJ04_RS09400	COG3661	Belongs to the glycosyl hydrolase 67 family
ICJ04_RS09415	COG1472	Belongs to the glycosyl hydrolase 3 family
ICJ04_RS09505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICJ04_RS09525	COG0363	glucosamine-6-phosphate deaminase activity
ICJ04_RS09535	COG1063	alcohol dehydrogenase
ICJ04_RS09545	COG2194	sulfuric ester hydrolase activity
ICJ04_RS09590	COG0477	Major facilitator Superfamily
ICJ04_RS09625	COG4774	siderophore transport
ICJ04_RS09630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICJ04_RS09635	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ICJ04_RS09640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ04_RS09645	COG4558	Periplasmic binding protein
ICJ04_RS09655	COG2819	hydrolase of the alpha beta superfamily
ICJ04_RS09660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICJ04_RS09665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICJ04_RS09670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ICJ04_RS09680	COG1674	ftsk spoiiie
ICJ04_RS09685	COG0492	ferredoxin-NADP+ reductase activity
ICJ04_RS09715	COG0542	response to heat
ICJ04_RS09720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ICJ04_RS09735	COG0482	sulfurtransferase activity
ICJ04_RS09740	COG2915	High frequency lysogenization protein hflD homolog
ICJ04_RS09770	COG5002	protein histidine kinase activity
ICJ04_RS09790	COG0835	chemotaxis
ICJ04_RS09790	COG0784	Response regulator, receiver
ICJ04_RS09795	COG1815	bacterial-type flagellum-dependent cell motility
ICJ04_RS09800	COG1558	bacterial-type flagellum-dependent cell motility
ICJ04_RS09815	COG4787	bacterial-type flagellum-dependent cell motility
ICJ04_RS09825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ICJ04_RS09835	COG3951	Flagellar rod assembly protein muramidase FlgJ
ICJ04_RS09835	COG1705	Flagellar rod assembly protein muramidase FlgJ
ICJ04_RS09860	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ICJ04_RS09880	COG2197	response regulator
ICJ04_RS09905	COG1677	Flagellar hook-basal body complex protein FliE
ICJ04_RS09910	COG1766	The M ring may be actively involved in energy transduction
ICJ04_RS09915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICJ04_RS09955	COG3190	flagellar
ICJ04_RS09965	COG1987	bacterial-type flagellum assembly
ICJ04_RS09980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICJ04_RS09985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICJ04_RS10015	COG0784	Response regulator, receiver
ICJ04_RS10015	COG0643	Histidine kinase
ICJ04_RS10015	COG2198	Histidine kinase
ICJ04_RS10020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICJ04_RS10035	COG0835	chemotaxis
ICJ04_RS10045	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS10055	COG0840	transmembrane signaling receptor activity
ICJ04_RS10060	COG0840	transmembrane signaling receptor activity
ICJ04_RS10065	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ICJ04_RS10070	COG0835	chemotaxis
ICJ04_RS10080	COG0840	transmembrane signaling receptor activity
ICJ04_RS10085	COG0840	transmembrane signaling receptor activity
ICJ04_RS10095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ICJ04_RS10100	COG2201	protein-glutamate methylesterase activity
ICJ04_RS10155	COG1309	transcriptional regulator
ICJ04_RS10160	COG1012	belongs to the aldehyde dehydrogenase family
ICJ04_RS10165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ICJ04_RS10170	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ04_RS10175	COG1024	Enoyl-CoA hydratase
ICJ04_RS10180	COG0784	Response regulator, receiver
ICJ04_RS10180	COG2205	protein histidine kinase activity
ICJ04_RS10180	COG2198	Histidine kinase
ICJ04_RS10190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ICJ04_RS10200	COG3279	Response regulator of the LytR AlgR family
ICJ04_RS10210	COG4676	Protein conserved in bacteria
ICJ04_RS10220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ICJ04_RS10230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ04_RS10235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICJ04_RS10245	COG0505	Belongs to the CarA family
ICJ04_RS10250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ICJ04_RS10265	COG1918	ferrous iron import across plasma membrane
ICJ04_RS10265	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ICJ04_RS10275	COG1024	Enoyl-CoA hydratase
ICJ04_RS10295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICJ04_RS10315	COG0277	FAD linked oxidase domain protein
ICJ04_RS10320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICJ04_RS10330	COG0531	amino acid
ICJ04_RS10335	COG0531	amino acid
ICJ04_RS10340	COG0235	Class ii aldolase
ICJ04_RS10345	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICJ04_RS10350	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ICJ04_RS10365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ04_RS10380	COG3537	Alpha-1,2-mannosidase
ICJ04_RS10390	COG3537	Alpha-1,2-mannosidase
ICJ04_RS10400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICJ04_RS10400	COG0140	phosphoribosyl-ATP diphosphatase activity
ICJ04_RS10405	COG0107	imidazoleglycerol-phosphate synthase activity
ICJ04_RS10410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICJ04_RS10420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICJ04_RS10420	COG0131	Imidazoleglycerol-phosphate dehydratase
ICJ04_RS10425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICJ04_RS10435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ICJ04_RS10445	COG0124	histidyl-tRNA synthetase
ICJ04_RS10450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ04_RS10465	COG0460	homoserine dehydrogenase
ICJ04_RS10465	COG0527	aspartate kinase activity
ICJ04_RS10475	COG2207	Transcriptional regulator
ICJ04_RS10480	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS10490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICJ04_RS10500	COG0784	Response regulator, receiver
ICJ04_RS10500	COG4191	Histidine kinase
ICJ04_RS10505	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS10630	COG1196	nuclear chromosome segregation
ICJ04_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
ICJ04_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS10660	COG0167	dihydroorotate dehydrogenase activity
ICJ04_RS10665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICJ04_RS10670	COG0697	spore germination
ICJ04_RS10685	COG2814	Major facilitator Superfamily
ICJ04_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS10720	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ04_RS10720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICJ04_RS10730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICJ04_RS10735	COG0475	glutathione-regulated potassium exporter activity
ICJ04_RS10735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICJ04_RS10740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICJ04_RS10745	COG1160	GTP binding
ICJ04_RS10750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICJ04_RS10770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICJ04_RS10775	COG0105	UTP biosynthetic process
ICJ04_RS10785	COG1024	Enoyl-CoA hydratase
ICJ04_RS10785	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICJ04_RS10790	COG0183	Belongs to the thiolase family
ICJ04_RS10795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICJ04_RS10810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ICJ04_RS10820	COG0776	regulation of translation
ICJ04_RS10830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ICJ04_RS10835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ICJ04_RS10845	COG2957	Belongs to the agmatine deiminase family
ICJ04_RS10850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ04_RS10865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS10875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ04_RS10890	COG0488	(ABC) transporter
ICJ04_RS10895	COG0513	Belongs to the DEAD box helicase family
ICJ04_RS10900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICJ04_RS10910	COG1414	Transcriptional regulator
ICJ04_RS10915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ04_RS10920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ04_RS10930	COG3485	protocatechuate 3,4-dioxygenase
ICJ04_RS10935	COG3485	protocatechuate 3,4-dioxygenase
ICJ04_RS10945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ICJ04_RS10960	COG0710	3-dehydroquinate dehydratase activity
ICJ04_RS10970	COG3420	alginic acid biosynthetic process
ICJ04_RS10975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ICJ04_RS10980	COG0625	glutathione transferase activity
ICJ04_RS10985	COG1278	Cold shock
ICJ04_RS10990	COG0564	pseudouridine synthase activity
ICJ04_RS10995	COG4681	YaeQ
ICJ04_RS11000	COG2081	HI0933 family
ICJ04_RS11010	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ICJ04_RS11015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICJ04_RS11025	COG1862	Preprotein translocase
ICJ04_RS11030	COG0343	queuine tRNA-ribosyltransferase activity
ICJ04_RS11035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICJ04_RS11040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICJ04_RS11070	COG1132	(ABC) transporter
ICJ04_RS11085	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ICJ04_RS11090	COG0484	heat shock protein binding
ICJ04_RS11095	COG0443	Heat shock 70 kDa protein
ICJ04_RS11100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICJ04_RS11105	COG1420	regulation of RNA biosynthetic process
ICJ04_RS11110	COG0497	DNA recombination
ICJ04_RS11115	COG0735	belongs to the Fur family
ICJ04_RS11120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICJ04_RS11135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICJ04_RS11165	COG0784	Response regulator, receiver
ICJ04_RS11190	COG5487	UPF0391 membrane protein
ICJ04_RS11230	COG0583	DNA-binding transcription factor activity
ICJ04_RS11240	COG0415	Belongs to the DNA photolyase family
ICJ04_RS11250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICJ04_RS11270	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICJ04_RS11275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ04_RS11280	COG0405	Gamma-glutamyltransferase
ICJ04_RS11285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICJ04_RS11295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICJ04_RS11300	COG0742	ribosomal rna small subunit methyltransferase
ICJ04_RS11305	COG0326	Molecular chaperone. Has ATPase activity
ICJ04_RS11310	COG0552	protein localization to endoplasmic reticulum
ICJ04_RS11350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ICJ04_RS11360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICJ04_RS11365	COG2009	succinate dehydrogenase
ICJ04_RS11380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICJ04_RS11385	COG0837	glucose binding
ICJ04_RS11410	COG0671	phosphoesterase, PA-phosphatase related
ICJ04_RS11415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICJ04_RS11425	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ICJ04_RS11430	COG0166	Belongs to the GPI family
ICJ04_RS11435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICJ04_RS11445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ICJ04_RS11450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ICJ04_RS11455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICJ04_RS11460	COG0617	tRNA 3'-terminal CCA addition
ICJ04_RS11470	COG0477	Major facilitator Superfamily
ICJ04_RS11480	COG1070	Carbohydrate kinase
ICJ04_RS11485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICJ04_RS11495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICJ04_RS11505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICJ04_RS11510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ICJ04_RS11520	COG0352	thiamine-phosphate diphosphorylase activity
ICJ04_RS11520	COG0351	phosphomethylpyrimidine kinase
ICJ04_RS11545	COG0583	DNA-binding transcription factor activity
ICJ04_RS11550	COG1741	Belongs to the pirin family
ICJ04_RS11615	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICJ04_RS11620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICJ04_RS11625	COG2137	regulation of response to DNA damage stimulus
ICJ04_RS11630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICJ04_RS11635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICJ04_RS11645	COG1546	Belongs to the CinA family
ICJ04_RS11650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICJ04_RS11660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICJ04_RS11665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICJ04_RS11680	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ICJ04_RS11685	COG1534	Rna-binding protein
ICJ04_RS11700	COG1238	metal cluster binding
ICJ04_RS11705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICJ04_RS11710	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ICJ04_RS11715	COG2840	Smr protein MutS2
ICJ04_RS11720	COG0585	pseudouridine synthase activity
ICJ04_RS11725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ICJ04_RS11730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ICJ04_RS11735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ICJ04_RS11740	COG0148	phosphopyruvate hydratase activity
ICJ04_RS11750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ICJ04_RS11755	COG0504	CTP synthase activity
ICJ04_RS11770	COG0306	phosphate transporter
ICJ04_RS11780	COG1253	flavin adenine dinucleotide binding
ICJ04_RS11795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICJ04_RS11800	COG1054	Belongs to the UPF0176 family
ICJ04_RS11810	COG0545	Peptidyl-prolyl cis-trans isomerase
ICJ04_RS11820	COG0456	acetyltransferase
ICJ04_RS11825	COG0069	glutamate synthase activity
ICJ04_RS11830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ICJ04_RS11860	COG0348	domain, Protein
ICJ04_RS11875	COG3179	chitinase
ICJ04_RS11945	COG0322	excinuclease ABC activity
ICJ04_RS11955	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICJ04_RS11960	COG1663	tetraacyldisaccharide 4'-kinase activity
ICJ04_RS11965	COG1132	(ABC) transporter
ICJ04_RS11970	COG0848	biopolymer transport protein
ICJ04_RS11975	COG0811	peptide transport
ICJ04_RS11980	COG0658	competence protein
ICJ04_RS11980	COG2333	competence protein COMEC
ICJ04_RS11990	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS12005	COG0556	nucleotide-excision repair
ICJ04_RS12050	COG1611	Belongs to the LOG family
ICJ04_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS12065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICJ04_RS12070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICJ04_RS12110	COG2969	positive regulation of protein catabolic process
ICJ04_RS12115	COG0625	glutathione transferase activity
ICJ04_RS12120	COG2857	Cytochrome c1
ICJ04_RS12125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ICJ04_RS12130	COG0723	plastoquinol--plastocyanin reductase activity
ICJ04_RS12135	COG0741	lytic transglycosylase activity
ICJ04_RS12145	COG0625	glutathione transferase activity
ICJ04_RS12150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICJ04_RS12155	COG1702	phosphate starvation-inducible protein PhoH
ICJ04_RS12160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICJ04_RS12175	COG4535	Mg2 and Co2 transporter CorC
ICJ04_RS12190	COG1012	belongs to the aldehyde dehydrogenase family
ICJ04_RS12195	COG1177	transmembrane transport
ICJ04_RS12200	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ04_RS12205	COG3842	ATPase activity
ICJ04_RS12230	COG0174	glutamine synthetase
ICJ04_RS12240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ04_RS12250	COG2703	oxygen carrier activity
ICJ04_RS12255	COG0477	Major facilitator Superfamily
ICJ04_RS12265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ICJ04_RS12275	COG2733	membrane
ICJ04_RS12310	COG0116	Belongs to the methyltransferase superfamily
ICJ04_RS12310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICJ04_RS12340	COG1024	Enoyl-CoA hydratase
ICJ04_RS12350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICJ04_RS12360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICJ04_RS12365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICJ04_RS12370	COG0573	inorganic phosphate transmembrane transporter activity
ICJ04_RS12375	COG0581	inorganic phosphate transmembrane transporter activity
ICJ04_RS12385	COG0704	Plays a role in the regulation of phosphate uptake
ICJ04_RS12390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICJ04_RS12410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ04_RS12415	COG1136	(ABC) transporter
ICJ04_RS12415	COG0577	efflux transmembrane transporter activity
ICJ04_RS12425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICJ04_RS12435	COG0557	exoribonuclease II activity
ICJ04_RS12470	COG2814	Major facilitator Superfamily
ICJ04_RS12475	COG1566	PFAM secretion protein HlyD family protein
ICJ04_RS12490	COG2207	Transcriptional regulator
ICJ04_RS12500	COG2193	ferroxidase activity
ICJ04_RS12510	COG0367	asparagine synthase
ICJ04_RS12525	COG1393	Belongs to the ArsC family
ICJ04_RS12535	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ICJ04_RS12575	COG0052	Belongs to the universal ribosomal protein uS2 family
ICJ04_RS12590	COG0528	UMP kinase activity
ICJ04_RS12600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICJ04_RS12605	COG0575	Belongs to the CDS family
ICJ04_RS12610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ICJ04_RS12615	COG0750	zinc metalloprotease
ICJ04_RS12630	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ04_RS12640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ04_RS12645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ04_RS12660	COG0825	malonyl-CoA metabolic process
ICJ04_RS12665	COG1981	membrane
ICJ04_RS12715	COG1132	(ABC) transporter
ICJ04_RS12720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICJ04_RS12745	COG1187	pseudouridine synthase activity
ICJ04_RS12755	COG5001	Diguanylate cyclase
ICJ04_RS12755	COG5002	protein histidine kinase activity
ICJ04_RS12765	COG2501	S4 domain
ICJ04_RS12805	COG1741	Belongs to the pirin family
ICJ04_RS12815	COG1741	Belongs to the pirin family
ICJ04_RS12820	COG1966	Carbon starvation protein
ICJ04_RS12825	COG2879	small protein
ICJ04_RS12845	COG2205	protein histidine kinase activity
ICJ04_RS12850	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS12865	COG2814	Major facilitator Superfamily
ICJ04_RS12870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICJ04_RS12870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICJ04_RS12885	COG1113	amino acid transport
ICJ04_RS12890	COG1917	Cupin 2, conserved barrel domain protein
ICJ04_RS12890	COG2207	Transcriptional regulator
ICJ04_RS12895	COG0753	catalase activity
ICJ04_RS12900	COG1376	ErfK ybiS ycfS ynhG family protein
ICJ04_RS12905	COG0739	heme binding
ICJ04_RS12920	COG0457	Tetratricopeptide repeat
ICJ04_RS12925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICJ04_RS12940	COG0330	HflC and HflK could
ICJ04_RS12945	COG0330	HflC and HflK could
ICJ04_RS12950	COG0604	alcohol dehydrogenase
ICJ04_RS12975	COG4953	penicillin-binding protein 1C
ICJ04_RS12980	COG3338	carbonate dehydratase activity
ICJ04_RS12985	COG2373	Large extracellular alpha-helical protein
ICJ04_RS12995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICJ04_RS13010	COG3829	transcription factor binding
ICJ04_RS13030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICJ04_RS13050	COG0477	Major facilitator Superfamily
ICJ04_RS13060	COG0784	Response regulator, receiver
ICJ04_RS13060	COG2198	Histidine kinase
ICJ04_RS13060	COG5002	protein histidine kinase activity
ICJ04_RS13065	COG2353	YceI-like domain
ICJ04_RS13070	COG3038	cytochrome b561
ICJ04_RS13085	COG1760	l-serine dehydratase
ICJ04_RS13090	COG0596	Alpha beta hydrolase
ICJ04_RS13090	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICJ04_RS13100	COG1404	Belongs to the peptidase S8 family
ICJ04_RS13110	COG4191	Histidine kinase
ICJ04_RS13115	COG0745	RESPONSE REGULATOR receiver
ICJ04_RS13120	COG0527	aspartate kinase activity
ICJ04_RS13120	COG0460	homoserine dehydrogenase
ICJ04_RS13125	COG0626	cystathionine gamma-synthase activity
ICJ04_RS13130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ04_RS13135	COG0739	heme binding
ICJ04_RS13140	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICJ04_RS13145	COG1272	protein, Hemolysin III
ICJ04_RS13150	COG2982	Protein involved in outer membrane biogenesis
ICJ04_RS13155	COG0517	IMP dehydrogenase activity
ICJ04_RS13160	COG0463	Glycosyl transferase, family 2
ICJ04_RS13170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICJ04_RS13185	COG1309	transcriptional regulator
ICJ04_RS13195	COG1960	acyl-CoA dehydrogenase activity
ICJ04_RS13220	COG0509	glycine decarboxylation via glycine cleavage system
ICJ04_RS13225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ICJ04_RS13235	COG0330	HflC and HflK could
ICJ04_RS13240	COG2186	Transcriptional regulator
ICJ04_RS13260	COG2271	Major facilitator Superfamily
ICJ04_RS13275	COG1742	UPF0060 membrane protein
ICJ04_RS13280	COG3956	TIGRFAM MazG family protein
ICJ04_RS13290	COG0494	nUDIX hydrolase
ICJ04_RS13295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICJ04_RS13310	COG2198	Histidine kinase
ICJ04_RS13310	COG0643	Histidine kinase
ICJ04_RS13310	COG0784	Response regulator, receiver
ICJ04_RS13315	COG0840	transmembrane signaling receptor activity
ICJ04_RS13320	COG0835	chemotaxis
ICJ04_RS13335	COG0189	ligase activity
ICJ04_RS13350	COG1199	ATP-dependent helicase activity
ICJ04_RS13360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICJ04_RS13375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICJ04_RS13390	COG1643	Atp-dependent helicase
ICJ04_RS13395	COG0783	Belongs to the Dps family
ICJ04_RS13400	COG0514	ATP-dependent DNA helicase (RecQ)
ICJ04_RS13410	COG2132	Multicopper oxidase
ICJ04_RS13430	COG3279	Response regulator of the LytR AlgR family
ICJ04_RS13455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICJ04_RS13460	COG0602	queuosine metabolic process
ICJ04_RS13470	COG2885	chlorophyll binding
ICJ04_RS13475	COG0823	Involved in the tonB-independent uptake of proteins
ICJ04_RS13495	COG0824	Thioesterase
ICJ04_RS13500	COG2255	four-way junction helicase activity
ICJ04_RS13510	COG0632	four-way junction helicase activity
ICJ04_RS13515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICJ04_RS13520	COG0217	transcriptional regulatory protein
ICJ04_RS13550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICJ04_RS13590	COG0488	(ABC) transporter
ICJ04_RS13600	COG4651	solute:proton antiporter activity
ICJ04_RS13600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICJ04_RS13615	COG3590	peptidase
ICJ04_RS13620	COG0542	response to heat
ICJ04_RS13635	COG0028	Belongs to the TPP enzyme family
ICJ04_RS13660	COG3387	PFAM Glycoside hydrolase 15-related
ICJ04_RS13665	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ICJ04_RS13675	COG0564	pseudouridine synthase activity
ICJ04_RS13680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICJ04_RS13705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ04_RS13705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ICJ04_RS13715	COG0045	succinate-CoA ligase (ADP-forming) activity
ICJ04_RS13745	COG0667	Aldo Keto reductase
ICJ04_RS13770	COG0583	DNA-binding transcription factor activity
ICJ04_RS13815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ04_RS13825	COG2205	protein histidine kinase activity
ICJ04_RS13845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICJ04_RS13850	COG0583	DNA-binding transcription factor activity
ICJ04_RS13865	COG0604	alcohol dehydrogenase
ICJ04_RS13890	COG2133	pyrroloquinoline quinone binding
ICJ04_RS13920	COG0583	DNA-binding transcription factor activity
ICJ04_RS13925	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS13945	COG1309	transcriptional regulator
ICJ04_RS13960	COG0583	DNA-binding transcription factor activity
ICJ04_RS13975	COG2198	Histidine kinase
ICJ04_RS13975	COG0784	Response regulator, receiver
ICJ04_RS13975	COG2205	protein histidine kinase activity
ICJ04_RS14000	COG0393	Putative heavy-metal-binding
ICJ04_RS14025	COG4993	Dehydrogenase
ICJ04_RS14040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICJ04_RS14060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICJ04_RS14065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICJ04_RS14070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICJ04_RS14075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ04_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS14100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICJ04_RS14105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ICJ04_RS14110	COG1399	metal-binding, possibly nucleic acid-binding protein
ICJ04_RS14125	COG0714	Associated with various cellular activities
ICJ04_RS14145	COG0537	adenosine 5'-monophosphoramidase activity
ICJ04_RS14155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICJ04_RS14160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICJ04_RS14225	COG4916	TIR domain
ICJ04_RS14255	COG1401	restriction endodeoxyribonuclease activity
ICJ04_RS14285	COG2249	NAD(P)H dehydrogenase (quinone) activity
ICJ04_RS14305	COG1234	tRNA 3'-trailer cleavage
ICJ04_RS14310	COG3642	lipopolysaccharide core region biosynthetic process
ICJ04_RS14315	COG0859	PFAM glycosyl transferase family 9
ICJ04_RS14330	COG0631	protein serine/threonine phosphatase activity
ICJ04_RS14335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICJ04_RS14350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ04_RS14355	COG3942	CHAP domain
ICJ04_RS14355	COG1388	LysM domain
ICJ04_RS14395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICJ04_RS14400	COG0740	serine-type endopeptidase activity
ICJ04_RS14405	COG0544	peptidyl-prolyl cis-trans isomerase activity
ICJ04_RS14520	COG0473	3-isopropylmalate dehydrogenase activity
ICJ04_RS14535	COG4783	chaperone-mediated protein folding
ICJ04_RS14555	COG0248	Ppx GppA phosphatase
ICJ04_RS14560	COG0438	transferase activity, transferring glycosyl groups
ICJ04_RS14565	COG0671	phosphoesterase, PA-phosphatase related
ICJ04_RS14570	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ04_RS14580	COG2833	Protein of unknown function (DUF455)
ICJ04_RS14590	COG1286	toxin biosynthetic process
ICJ04_RS14600	COG0285	dihydrofolate synthase activity
ICJ04_RS14605	COG0406	alpha-ribazole phosphatase activity
ICJ04_RS14615	COG1063	alcohol dehydrogenase
ICJ04_RS14635	COG1187	pseudouridine synthase activity
ICJ04_RS14650	COG2364	Membrane
ICJ04_RS14655	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICJ04_RS14655	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS14665	COG0625	glutathione transferase activity
ICJ04_RS14675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ04_RS14685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICJ04_RS14700	COG0154	amidase activity
ICJ04_RS14710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ICJ04_RS14720	COG0203	ribosomal protein L17
ICJ04_RS14725	COG0202	RNA polymerase activity
ICJ04_RS14730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICJ04_RS14735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICJ04_RS14745	COG0201	protein transport
ICJ04_RS14755	COG1841	ribosomal large subunit assembly
ICJ04_RS14760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICJ04_RS14765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICJ04_RS14770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICJ04_RS14775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICJ04_RS14780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICJ04_RS14785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICJ04_RS14790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICJ04_RS14800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICJ04_RS14805	COG0255	Belongs to the universal ribosomal protein uL29 family
ICJ04_RS14810	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICJ04_RS14820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICJ04_RS14825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICJ04_RS14830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICJ04_RS14835	COG0089	rRNA binding
ICJ04_RS14840	COG0088	Forms part of the polypeptide exit tunnel
ICJ04_RS14845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICJ04_RS14850	COG0051	transcription antitermination factor activity, RNA binding
ICJ04_RS14855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICJ04_RS14860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICJ04_RS14865	COG0049	tRNA binding
ICJ04_RS14870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICJ04_RS14875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICJ04_RS14880	COG0085	RNA polymerase activity
ICJ04_RS14885	COG0222	ribosome binding
ICJ04_RS14890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICJ04_RS14895	COG0081	regulation of translation
ICJ04_RS14900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICJ04_RS14905	COG0250	Participates in transcription elongation, termination and antitermination
ICJ04_RS14920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICJ04_RS14940	COG1446	asparaginase
ICJ04_RS14950	COG0012	GTP binding
ICJ04_RS14955	COG0193	aminoacyl-tRNA hydrolase activity
ICJ04_RS14960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ICJ04_RS14965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICJ04_RS14975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICJ04_RS14990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICJ04_RS14995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICJ04_RS15010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICJ04_RS15015	COG1295	ribonuclease BN
ICJ04_RS15035	COG1404	Belongs to the peptidase S8 family
ICJ04_RS15040	COG1404	Belongs to the peptidase S8 family
ICJ04_RS15045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICJ04_RS15050	COG2151	metal-sulfur cluster biosynthetic enzyme
ICJ04_RS15085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ICJ04_RS15135	COG3209	COG3209 Rhs family protein
ICJ04_RS15135	COG4104	PAAR repeat-containing protein
ICJ04_RS15195	COG3634	alkyl hydroperoxide reductase activity
ICJ04_RS15200	COG0583	DNA-binding transcription factor activity
ICJ04_RS15205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ04_RS15225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICJ04_RS15235	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ICJ04_RS15250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICJ04_RS15255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICJ04_RS15270	COG2096	Adenosyltransferase
ICJ04_RS15280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICJ04_RS15290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICJ04_RS15300	COG2967	ApaG domain
ICJ04_RS15305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICJ04_RS15310	COG1505	serine-type exopeptidase activity
ICJ04_RS15330	COG2011	ABC-type metal ion transport system permease component
ICJ04_RS15335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICJ04_RS15345	COG0697	spore germination
ICJ04_RS15350	COG1666	GTP binding
ICJ04_RS15375	COG0339	signal peptide processing
ICJ04_RS15380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICJ04_RS15395	COG1902	pentaerythritol trinitrate reductase activity
ICJ04_RS15400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICJ04_RS15410	COG1136	(ABC) transporter
ICJ04_RS15420	COG0577	efflux transmembrane transporter activity
ICJ04_RS15425	COG2204	response regulator
ICJ04_RS15430	COG4191	Histidine kinase
ICJ04_RS15435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICJ04_RS15455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ICJ04_RS15460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICJ04_RS15465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICJ04_RS15470	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICJ04_RS15475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICJ04_RS15480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICJ04_RS15490	COG0356	it plays a direct role in the translocation of protons across the membrane
ICJ04_RS15505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICJ04_RS15510	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICJ04_RS15540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICJ04_RS15565	COG0181	hydroxymethylbilane synthase activity
ICJ04_RS15575	COG3275	phosphorelay sensor kinase activity
ICJ04_RS15580	COG0400	carboxylic ester hydrolase activity
ICJ04_RS15610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICJ04_RS15720	COG0210	DNA helicase
ICJ04_RS15755	COG2233	PERMEase
ICJ04_RS15765	COG3550	peptidyl-serine autophosphorylation
ICJ04_RS15770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICJ04_RS15775	COG1490	D-aminoacyl-tRNA deacylase activity
ICJ04_RS15785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICJ04_RS15825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICJ04_RS15830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICJ04_RS15830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICJ04_RS15835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICJ04_RS15840	COG0242	peptide deformylase activity
ICJ04_RS15850	COG0758	DNA mediated transformation
ICJ04_RS15855	COG2922	Belongs to the Smg family
ICJ04_RS15865	COG1714	RDD family
ICJ04_RS15875	COG0009	L-threonylcarbamoyladenylate synthase
ICJ04_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS15900	COG0616	signal peptide processing
ICJ04_RS15905	COG0534	Mate efflux family protein
ICJ04_RS15920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICJ04_RS15925	COG0625	glutathione transferase activity
ICJ04_RS15935	COG1252	NADH dehydrogenase
ICJ04_RS15945	COG2860	membrane
ICJ04_RS15960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS15965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICJ04_RS15975	COG0459	protein refolding
ICJ04_RS15980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICJ04_RS15985	COG2356	endonuclease I
ICJ04_RS15990	COG1324	tolerance protein
ICJ04_RS16000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICJ04_RS16010	COG0583	DNA-binding transcription factor activity
ICJ04_RS16015	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS16020	COG0840	transmembrane signaling receptor activity
ICJ04_RS16055	COG1201	RNA secondary structure unwinding
ICJ04_RS16115	COG0583	DNA-binding transcription factor activity
ICJ04_RS16130	COG0402	S-adenosylhomocysteine deaminase activity
ICJ04_RS16135	COG0583	DNA-binding transcription factor activity
ICJ04_RS16180	COG0583	DNA-binding transcription factor activity
ICJ04_RS16190	COG0038	chloride channel
ICJ04_RS16195	COG2433	Pfam Transposase IS66
ICJ04_RS16210	COG5290	Psort location Cytoplasmic, score
ICJ04_RS16235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICJ04_RS16240	COG0511	ligase activity, forming carbon-carbon bonds
ICJ04_RS16245	COG0439	Biotin carboxylase
ICJ04_RS16260	COG2264	protein methyltransferase activity
ICJ04_RS16270	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ICJ04_RS16275	COG0138	bifunctional purine biosynthesis protein purh
ICJ04_RS16285	COG0151	Belongs to the GarS family
ICJ04_RS16315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICJ04_RS16320	COG2201	protein-glutamate methylesterase activity
ICJ04_RS16325	COG2177	Part of the ABC transporter FtsEX involved in
ICJ04_RS16330	COG2884	Cell division ATP-binding protein ftsE
ICJ04_RS16335	COG0513	Belongs to the DEAD box helicase family
ICJ04_RS16345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICJ04_RS16350	COG1609	Transcriptional regulator
ICJ04_RS16365	COG3706	GGDEF domain
ICJ04_RS16375	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ICJ04_RS16390	COG1652	LysM domain
ICJ04_RS16395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICJ04_RS16395	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICJ04_RS16400	COG1473	amidohydrolase
ICJ04_RS16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ04_RS16420	COG1289	transmembrane transporter activity
ICJ04_RS16455	COG0316	Belongs to the HesB IscA family
ICJ04_RS16495	COG1051	belongs to the nudix hydrolase family
ICJ04_RS16510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ICJ04_RS16515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICJ04_RS16520	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ICJ04_RS16530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICJ04_RS16535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ04_RS16540	COG0730	response to heat
ICJ04_RS16550	COG0134	indole-3-glycerol-phosphate synthase activity
ICJ04_RS16555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICJ04_RS16565	COG2968	Membrane
ICJ04_RS16585	COG1597	lipid kinase activity
ICJ04_RS16600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICJ04_RS16605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ICJ04_RS16615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ICJ04_RS16615	COG2111	Na H antiporter
ICJ04_RS16620	COG1006	Multisubunit Na H antiporter MnhC subunit
ICJ04_RS16625	COG0651	ATP synthesis coupled electron transport
ICJ04_RS16635	COG2212	antiporter activity
ICJ04_RS16640	COG1320	monovalent cation:proton antiporter activity
ICJ04_RS16660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ICJ04_RS16685	COG3104	oligopeptide transport
ICJ04_RS16695	COG3483	tryptophan 2,3-dioxygenase activity
ICJ04_RS16700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ICJ04_RS16720	COG0702	epimerase
ICJ04_RS16730	COG2354	Protein conserved in bacteria
ICJ04_RS16735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICJ04_RS16745	COG1196	nuclear chromosome segregation
ICJ04_RS16745	COG3264	Mechanosensitive ion channel
ICJ04_RS16755	COG3040	lipid binding
ICJ04_RS16760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ICJ04_RS16790	COG1166	arginine decarboxylase activity
ICJ04_RS16795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ICJ04_RS16815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ04_RS16835	COG0347	Belongs to the P(II) protein family
ICJ04_RS16840	COG2960	long-chain fatty acid transporting porin activity
ICJ04_RS16865	COG0473	3-isopropylmalate dehydrogenase activity
ICJ04_RS16875	COG0435	Glutathione S-transferase
ICJ04_RS16910	COG0606	chelatase, subunit chli
ICJ04_RS16930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICJ04_RS16955	COG1040	competence protein
ICJ04_RS16965	COG0156	8-amino-7-oxononanoate synthase activity
ICJ04_RS16970	COG2267	carboxylic ester hydrolase activity
ICJ04_RS16975	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS16990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICJ04_RS17005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICJ04_RS17030	COG0714	Associated with various cellular activities
ICJ04_RS17040	COG0754	glutathionylspermidine amidase activity
ICJ04_RS17050	COG0129	dihydroxy-acid dehydratase activity
ICJ04_RS17060	COG1199	ATP-dependent helicase activity
ICJ04_RS17070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICJ04_RS17120	COG3291	Pkd domain containing protein
ICJ04_RS17130	COG0625	glutathione transferase activity
ICJ04_RS17155	COG4555	ABC transporter
ICJ04_RS17165	COG0583	DNA-binding transcription factor activity
ICJ04_RS17170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ04_RS17175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICJ04_RS17195	COG1131	(ABC) transporter
ICJ04_RS17200	COG0842	Transport permease protein
ICJ04_RS17210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICJ04_RS17220	COG0084	hydrolase, TatD family'
ICJ04_RS17225	COG1643	Atp-dependent helicase
ICJ04_RS17235	COG1187	pseudouridine synthase activity
ICJ04_RS17245	COG0667	Aldo Keto reductase
ICJ04_RS17255	COG3634	alkyl hydroperoxide reductase activity
ICJ04_RS17265	COG0840	transmembrane signaling receptor activity
ICJ04_RS17270	COG0583	DNA-binding transcription factor activity
ICJ04_RS17275	COG2814	Major facilitator Superfamily
ICJ04_RS17285	COG2267	carboxylic ester hydrolase activity
ICJ04_RS17295	COG2239	Acts as a magnesium transporter
ICJ04_RS17310	COG3100	YcgL domain-containing protein
ICJ04_RS17315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ04_RS17320	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ04_RS17330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ04_RS17355	COG2986	histidine ammonia-lyase
ICJ04_RS17365	COG1216	Glycosyl transferase, family 2
ICJ04_RS17380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ04_RS17385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ04_RS17400	COG1271	oxidase subunit
ICJ04_RS17405	COG1294	oxidase, subunit
ICJ04_RS17445	COG0408	coproporphyrinogen oxidase activity
ICJ04_RS17475	COG0589	response to stress
ICJ04_RS17490	COG0210	DNA helicase
ICJ04_RS17500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ04_RS17505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ICJ04_RS17510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ICJ04_RS17515	COG1819	glycosyl
ICJ04_RS17535	COG0251	oxidation-reduction process
ICJ04_RS17575	COG0463	Glycosyl transferase, family 2
ICJ04_RS17590	COG1475	DNA binding
ICJ04_RS17595	COG1192	Involved in chromosome partitioning
ICJ04_RS17600	COG0357	Ribosomal RNA small subunit methyltransferase G
ICJ04_RS17605	COG2091	lysine biosynthetic process via aminoadipic acid
ICJ04_RS17625	COG0564	pseudouridine synthase activity
ICJ04_RS17645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICJ04_RS17650	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ04_RS17660	COG0596	Alpha beta hydrolase
ICJ04_RS17665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICJ04_RS17680	COG0477	Major facilitator Superfamily
ICJ04_RS17700	COG1971	Probably functions as a manganese efflux pump
ICJ04_RS17710	COG2205	protein histidine kinase activity
ICJ04_RS17710	COG0784	Response regulator, receiver
ICJ04_RS17725	COG0729	surface antigen
ICJ04_RS17765	COG0741	lytic transglycosylase activity
ICJ04_RS17770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ04_RS17860	COG2207	Transcriptional regulator
ICJ04_RS17870	COG0752	glycyl-tRNA synthetase alpha subunit
ICJ04_RS17875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICJ04_RS17880	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ04_RS17880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICJ04_RS17890	COG0805	protein transport
ICJ04_RS17900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICJ04_RS17910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ICJ04_RS17975	COG3135	benzoate transporter
ICJ04_RS17980	COG0676	glucose-6-phosphate 1-epimerase activity
ICJ04_RS17985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ICJ04_RS17990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ICJ04_RS18020	COG0302	gtp cyclohydrolase
ICJ04_RS18040	COG1538	Outer membrane efflux protein
ICJ04_RS18045	COG1289	transmembrane transporter activity
ICJ04_RS18055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICJ04_RS18060	COG1074	ATP-dependent DNA helicase activity
ICJ04_RS18065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ICJ04_RS18070	COG1127	ABC transporter
ICJ04_RS18075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICJ04_RS18080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICJ04_RS18095	COG2853	Lipoprotein
ICJ04_RS18100	COG0386	Belongs to the glutathione peroxidase family
ICJ04_RS18110	COG1322	Protein conserved in bacteria
ICJ04_RS18120	COG0583	DNA-binding transcription factor activity
ICJ04_RS18130	COG0531	amino acid
ICJ04_RS18140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICJ04_RS18145	COG0861	Integral membrane protein TerC family
ICJ04_RS18155	COG0584	glycerophosphoryl diester phosphodiesterase
ICJ04_RS18170	COG0706	membrane insertase activity
ICJ04_RS18175	COG0594	ribonuclease P activity
ICJ04_RS18180	COG0230	Belongs to the bacterial ribosomal protein bL34 family