locus-tag	class	description
GQ674_RS00010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQ674_RS00020	COG2186	Transcriptional regulator
GQ674_RS00035	COG2814	Major facilitator Superfamily
GQ674_RS00045	COG4807	Protein conserved in bacteria
GQ674_RS00055	COG4221	oxidoreductase activity
GQ674_RS00075	COG0018	arginyl-trna synthetase
GQ674_RS00080	COG2003	Belongs to the UPF0758 family
GQ674_RS00085	COG3177	Filamentation induced by cAMP protein fic
GQ674_RS00090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GQ674_RS00095	COG0756	dUTP diphosphatase activity
GQ674_RS00110	COG2205	protein histidine kinase activity
GQ674_RS00120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GQ674_RS00125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GQ674_RS00140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQ674_RS00145	COG0708	Exodeoxyribonuclease III
GQ674_RS00150	COG2223	nitrite transmembrane transporter activity
GQ674_RS00165	COG0739	heme binding
GQ674_RS00170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQ674_RS00215	COG4942	peptidase
GQ674_RS00220	COG0793	Belongs to the peptidase S41A family
GQ674_RS00245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQ674_RS00255	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GQ674_RS00285	COG0109	protoheme IX farnesyltransferase activity
GQ674_RS00315	COG0358	DNA primase activity
GQ674_RS00320	COG1295	ribonuclease BN
GQ674_RS00325	COG1610	YqeY-like protein
GQ674_RS00330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQ674_RS00335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQ674_RS00340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQ674_RS00345	COG0668	transmembrane transport
GQ674_RS00360	COG2133	pyrroloquinoline quinone binding
GQ674_RS00365	COG4682	membrane
GQ674_RS00375	COG0531	amino acid
GQ674_RS00385	COG1737	Transcriptional regulator
GQ674_RS00390	COG4948	Mandelate Racemase Muconate Lactonizing
GQ674_RS00420	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GQ674_RS00450	COG5383	Protein conserved in bacteria
GQ674_RS00460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GQ674_RS00495	COG0778	Nitroreductase
GQ674_RS00500	COG2353	YceI-like domain
GQ674_RS00530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQ674_RS00610	COG3391	amine dehydrogenase activity
GQ674_RS00645	COG2267	carboxylic ester hydrolase activity
GQ674_RS00665	COG1943	Transposase
GQ674_RS00710	COG0488	(ABC) transporter
GQ674_RS00715	COG0583	DNA-binding transcription factor activity
GQ674_RS00720	COG2814	Major facilitator Superfamily
GQ674_RS00730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GQ674_RS00735	COG1113	amino acid transport
GQ674_RS00760	COG3795	YCII-related domain
GQ674_RS00765	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GQ674_RS00775	COG4941	Belongs to the sigma-70 factor family
GQ674_RS00785	COG3275	phosphorelay sensor kinase activity
GQ674_RS00790	COG3279	Response regulator of the LytR AlgR family
GQ674_RS00810	COG3590	peptidase
GQ674_RS00815	COG5001	Diguanylate cyclase
GQ674_RS00815	COG3300	MHYT domain
GQ674_RS00830	COG3384	dioxygenase
GQ674_RS00840	COG0025	NhaP-type Na H and K H
GQ674_RS00865	COG1360	Flagellar Motor Protein
GQ674_RS00890	COG1522	sequence-specific DNA binding
GQ674_RS00895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQ674_RS00910	COG4999	Histidine kinase
GQ674_RS00910	COG3850	Histidine kinase
GQ674_RS00910	COG3437	response regulator, receiver
GQ674_RS00910	COG2205	protein histidine kinase activity
GQ674_RS00930	COG1187	pseudouridine synthase activity
GQ674_RS00935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQ674_RS00945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQ674_RS00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQ674_RS00965	COG0583	DNA-binding transcription factor activity
GQ674_RS00975	COG4206	TonB-dependent receptor
GQ674_RS00990	COG1956	GAF domain-containing protein
GQ674_RS01000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQ674_RS01005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQ674_RS01010	COG0785	Cytochrome C biogenesis protein
GQ674_RS01010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS01015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQ674_RS01020	COG0745	RESPONSE REGULATOR receiver
GQ674_RS01035	COG0720	synthase
GQ674_RS01055	COG0513	Belongs to the DEAD box helicase family
GQ674_RS01065	COG0625	glutathione transferase activity
GQ674_RS01095	COG0626	cystathionine gamma-synthase activity
GQ674_RS01125	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GQ674_RS01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQ674_RS01160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQ674_RS01165	COG2076	Multidrug Resistance protein
GQ674_RS01185	COG2086	electron transfer activity
GQ674_RS01235	COG1127	ABC transporter
GQ674_RS01240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQ674_RS01255	COG0442	prolyl-tRNA aminoacylation
GQ674_RS01265	COG1183	phosphatidylcholine synthase activity
GQ674_RS01285	COG0525	valine-tRNA ligase activity
GQ674_RS01300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQ674_RS01310	COG0795	lipopolysaccharide-transporting ATPase activity
GQ674_RS01320	COG4974	Belongs to the 'phage' integrase family
GQ674_RS01335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQ674_RS01345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQ674_RS01345	COG0047	phosphoribosylformylglycinamidine synthase activity
GQ674_RS01350	COG5295	Hep Hag repeat protein
GQ674_RS01355	COG1404	Belongs to the peptidase S8 family
GQ674_RS01360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQ674_RS01365	COG1459	type II secretion system
GQ674_RS01370	COG2165	general secretion pathway protein
GQ674_RS01375	COG4970	Tfp pilus assembly protein FimT
GQ674_RS01380	COG2165	general secretion pathway protein
GQ674_RS01385	COG4795	General secretion pathway protein
GQ674_RS01390	COG3156	type II secretion system protein K
GQ674_RS01395	COG3166	PFAM Fimbrial assembly family protein
GQ674_RS01410	COG1450	Type ii and iii secretion system protein
GQ674_RS01435	COG3539	Fimbrial protein
GQ674_RS01440	COG3121	Chaperone
GQ674_RS01455	COG2252	PERMEase
GQ674_RS01460	COG0488	(ABC) transporter
GQ674_RS01470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQ674_RS01485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQ674_RS01490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQ674_RS01490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQ674_RS01515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQ674_RS01520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQ674_RS01560	COG4789	Type iii secretion
GQ674_RS01570	COG1157	protein secretion by the type III secretion system
GQ674_RS01645	COG0741	lytic transglycosylase activity
GQ674_RS01685	COG3121	Chaperone
GQ674_RS01720	COG0277	FAD linked oxidase domain protein
GQ674_RS01725	COG1988	membrane-bound metal-dependent
GQ674_RS01760	COG2001	Belongs to the MraZ family
GQ674_RS01765	COG0275	rRNA processing
GQ674_RS01770	COG3116	cell division
GQ674_RS01780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQ674_RS01785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQ674_RS01810	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQ674_RS01815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GQ674_RS01825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQ674_RS01830	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GQ674_RS01840	COG0739	heme binding
GQ674_RS01845	COG0653	protein targeting
GQ674_RS01850	COG0494	nUDIX hydrolase
GQ674_RS01860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GQ674_RS01865	COG1090	epimerase
GQ674_RS01870	COG2205	protein histidine kinase activity
GQ674_RS01875	COG0745	RESPONSE REGULATOR receiver
GQ674_RS01895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQ674_RS01905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQ674_RS01920	COG1607	acyl-coa hydrolase
GQ674_RS01930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQ674_RS01950	COG4106	trans-aconitate 2-methyltransferase activity
GQ674_RS01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQ674_RS01990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQ674_RS01995	COG0667	Aldo Keto reductase
GQ674_RS02005	COG4771	TonB-dependent receptor
GQ674_RS02020	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GQ674_RS02025	COG4181	ATPase activity
GQ674_RS02040	COG0642	Histidine kinase
GQ674_RS02050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GQ674_RS02055	COG0861	Integral membrane protein TerC family
GQ674_RS02075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQ674_RS02095	COG3738	Protein conserved in bacteria
GQ674_RS02105	COG2967	ApaG domain
GQ674_RS02115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GQ674_RS02120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQ674_RS02125	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GQ674_RS02135	COG2096	Adenosyltransferase
GQ674_RS02145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQ674_RS02150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQ674_RS02160	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GQ674_RS02170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQ674_RS02180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQ674_RS02190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQ674_RS02195	COG0583	DNA-binding transcription factor activity
GQ674_RS02200	COG3634	alkyl hydroperoxide reductase activity
GQ674_RS02250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQ674_RS02250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQ674_RS02265	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQ674_RS02285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQ674_RS02290	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQ674_RS02300	COG2151	metal-sulfur cluster biosynthetic enzyme
GQ674_RS02305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQ674_RS02310	COG1404	Belongs to the peptidase S8 family
GQ674_RS02330	COG1295	ribonuclease BN
GQ674_RS02335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS02355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQ674_RS02360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQ674_RS02375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GQ674_RS02385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQ674_RS02395	COG0193	aminoacyl-tRNA hydrolase activity
GQ674_RS02400	COG0012	GTP binding
GQ674_RS02405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQ674_RS02420	COG1446	asparaginase
GQ674_RS02440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQ674_RS02450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQ674_RS02455	COG0250	Participates in transcription elongation, termination and antitermination
GQ674_RS02460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQ674_RS02465	COG0081	regulation of translation
GQ674_RS02470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQ674_RS02475	COG0222	ribosome binding
GQ674_RS02480	COG0085	RNA polymerase activity
GQ674_RS02485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQ674_RS02500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQ674_RS02505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQ674_RS02510	COG0051	transcription antitermination factor activity, RNA binding
GQ674_RS02515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQ674_RS02520	COG0088	Forms part of the polypeptide exit tunnel
GQ674_RS02525	COG0089	rRNA binding
GQ674_RS02530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQ674_RS02535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQ674_RS02540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQ674_RS02550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQ674_RS02555	COG0255	Belongs to the universal ribosomal protein uL29 family
GQ674_RS02560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQ674_RS02565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQ674_RS02570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQ674_RS02575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQ674_RS02580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQ674_RS02585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQ674_RS02595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQ674_RS02600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQ674_RS02605	COG1841	ribosomal large subunit assembly
GQ674_RS02615	COG0201	protein transport
GQ674_RS02620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQ674_RS02625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQ674_RS02630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQ674_RS02635	COG0202	RNA polymerase activity
GQ674_RS02640	COG0203	ribosomal protein L17
GQ674_RS02645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GQ674_RS02655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GQ674_RS02665	COG0154	amidase activity
GQ674_RS02680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQ674_RS02685	COG0039	L-malate dehydrogenase activity
GQ674_RS02690	COG2207	Transcriptional regulator
GQ674_RS02695	COG0667	Aldo Keto reductase
GQ674_RS02705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQ674_RS02720	COG0625	glutathione transferase activity
GQ674_RS02730	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQ674_RS02730	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS02735	COG2364	Membrane
GQ674_RS02755	COG1187	pseudouridine synthase activity
GQ674_RS02765	COG0156	8-amino-7-oxononanoate synthase activity
GQ674_RS02775	COG1063	alcohol dehydrogenase
GQ674_RS02785	COG0406	alpha-ribazole phosphatase activity
GQ674_RS02790	COG0285	dihydrofolate synthase activity
GQ674_RS02810	COG2833	Protein of unknown function (DUF455)
GQ674_RS02820	COG3291	Pkd domain containing protein
GQ674_RS02830	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQ674_RS02835	COG0671	phosphoesterase, PA-phosphatase related
GQ674_RS02840	COG0438	transferase activity, transferring glycosyl groups
GQ674_RS02850	COG0248	Ppx GppA phosphatase
GQ674_RS02855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GQ674_RS02870	COG4783	chaperone-mediated protein folding
GQ674_RS02885	COG0473	3-isopropylmalate dehydrogenase activity
GQ674_RS02910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQ674_RS02960	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQ674_RS02965	COG0740	serine-type endopeptidase activity
GQ674_RS02970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQ674_RS03005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQ674_RS03010	COG1388	LysM domain
GQ674_RS03010	COG3942	CHAP domain
GQ674_RS03015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQ674_RS03025	COG0328	RNA-DNA hybrid ribonuclease activity
GQ674_RS03030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQ674_RS03035	COG0631	protein serine/threonine phosphatase activity
GQ674_RS03050	COG0859	PFAM glycosyl transferase family 9
GQ674_RS03055	COG3642	lipopolysaccharide core region biosynthetic process
GQ674_RS03060	COG1234	tRNA 3'-trailer cleavage
GQ674_RS03105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQ674_RS03115	COG0537	adenosine 5'-monophosphoramidase activity
GQ674_RS03135	COG0714	Associated with various cellular activities
GQ674_RS03150	COG1399	metal-binding, possibly nucleic acid-binding protein
GQ674_RS03155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQ674_RS03160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQ674_RS03170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQ674_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS03185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQ674_RS03190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQ674_RS03195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQ674_RS03200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQ674_RS03235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQ674_RS03265	COG0583	DNA-binding transcription factor activity
GQ674_RS03270	COG0477	Major facilitator Superfamily
GQ674_RS03310	COG0583	DNA-binding transcription factor activity
GQ674_RS03320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GQ674_RS03340	COG0667	Aldo Keto reductase
GQ674_RS03365	COG2818	Glycosylase
GQ674_RS03370	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GQ674_RS03375	COG1678	Uncharacterized ACR, COG1678
GQ674_RS03380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQ674_RS03385	COG0540	Belongs to the ATCase OTCase family
GQ674_RS03410	COG2239	Acts as a magnesium transporter
GQ674_RS03415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQ674_RS03430	COG1660	Displays ATPase and GTPase activities
GQ674_RS03435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GQ674_RS03440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQ674_RS03455	COG1137	ATPase activity
GQ674_RS03470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GQ674_RS03485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQ674_RS03505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GQ674_RS03520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQ674_RS03530	COG0628	permease
GQ674_RS03540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQ674_RS03545	COG3178	'Phosphotransferase
GQ674_RS03550	COG2261	transglycosylase associated protein
GQ674_RS03560	COG1555	photosystem II stabilization
GQ674_RS03560	COG1596	polysaccharide export
GQ674_RS03580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQ674_RS03585	COG1477	protein flavinylation
GQ674_RS03605	COG4771	TonB-dependent receptor
GQ674_RS03615	COG3128	pkhd-type hydroxylase
GQ674_RS03620	COG4774	siderophore transport
GQ674_RS03650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQ674_RS03655	COG0719	Fe-S assembly protein
GQ674_RS03660	COG0396	ATPase activity
GQ674_RS03665	COG0719	Fe-S assembly protein
GQ674_RS03670	COG1959	2 iron, 2 sulfur cluster binding
GQ674_RS03680	COG0693	protein deglycase activity
GQ674_RS03705	COG1764	response to oxidative stress
GQ674_RS03710	COG0384	phenazine biosynthesis protein PhzF
GQ674_RS03715	COG0527	aspartate kinase activity
GQ674_RS03725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQ674_RS03740	COG0142	geranyltranstransferase activity
GQ674_RS03745	COG0366	Alpha amylase catalytic
GQ674_RS03755	COG1082	Xylose isomerase domain protein TIM barrel
GQ674_RS03765	COG2211	Major facilitator Superfamily
GQ674_RS03765	COG2190	(PTS) system
GQ674_RS03780	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQ674_RS03795	COG1131	(ABC) transporter
GQ674_RS03810	COG0629	single-stranded DNA binding
GQ674_RS03840	COG2010	Cytochrome c
GQ674_RS03850	COG0673	inositol 2-dehydrogenase activity
GQ674_RS03855	COG2211	Major facilitator Superfamily
GQ674_RS03915	COG1408	metallophosphoesterase
GQ674_RS03940	COG0640	Transcriptional regulator
GQ674_RS03960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQ674_RS03965	COG0477	Major facilitator Superfamily
GQ674_RS03970	COG1802	Transcriptional regulator
GQ674_RS04005	COG3052	prosthetic group binding
GQ674_RS04020	COG0579	oxidoreductase
GQ674_RS04060	COG3104	oligopeptide transport
GQ674_RS04070	COG1297	OPT oligopeptide transporter protein
GQ674_RS04075	COG1506	peptidase
GQ674_RS04075	COG0823	Involved in the tonB-independent uptake of proteins
GQ674_RS04090	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GQ674_RS04095	COG2894	cell division
GQ674_RS04115	COG2197	response regulator
GQ674_RS04130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GQ674_RS04160	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQ674_RS04170	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GQ674_RS04180	COG1595	DNA-templated transcription, initiation
GQ674_RS04190	COG1946	Acyl-CoA thioesterase
GQ674_RS04210	COG0824	Thioesterase
GQ674_RS04215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQ674_RS04225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQ674_RS04230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQ674_RS04240	COG0728	peptidoglycan biosynthetic process
GQ674_RS04245	COG0196	riboflavin kinase activity
GQ674_RS04250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQ674_RS04260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQ674_RS04290	COG3209	COG3209 Rhs family protein
GQ674_RS04330	COG0596	Alpha beta hydrolase
GQ674_RS04335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQ674_RS04340	COG1620	l-lactate permease
GQ674_RS04350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQ674_RS04355	COG1845	cytochrome c oxidase, subunit III
GQ674_RS04360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GQ674_RS04375	COG0326	Molecular chaperone. Has ATPase activity
GQ674_RS04395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQ674_RS04405	COG2070	2-Nitropropane dioxygenase
GQ674_RS04420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQ674_RS04425	COG0336	Belongs to the RNA methyltransferase TrmD family
GQ674_RS04440	COG0534	Mate efflux family protein
GQ674_RS04460	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GQ674_RS04470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQ674_RS04500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQ674_RS04540	COG1309	transcriptional regulator
GQ674_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS04580	COG3300	MHYT domain
GQ674_RS04580	COG5001	Diguanylate cyclase
GQ674_RS04600	COG0784	Response regulator, receiver
GQ674_RS04600	COG4191	Histidine kinase
GQ674_RS04605	COG0840	transmembrane signaling receptor activity
GQ674_RS04635	COG5001	Diguanylate cyclase
GQ674_RS04635	COG3447	MASE1 domain protein
GQ674_RS04635	COG5002	protein histidine kinase activity
GQ674_RS04650	COG3300	MHYT domain
GQ674_RS04650	COG5001	Diguanylate cyclase
GQ674_RS04665	COG2197	response regulator
GQ674_RS04670	COG1335	isochorismatase
GQ674_RS04675	COG3685	Protein conserved in bacteria
GQ674_RS04730	COG3713	MltA-interacting MipA family protein
GQ674_RS04735	COG0583	DNA-binding transcription factor activity
GQ674_RS04755	COG1073	alpha beta
GQ674_RS04785	COG4948	Mandelate Racemase Muconate Lactonizing
GQ674_RS04790	COG0800	Aldolase
GQ674_RS04795	COG1802	Transcriptional regulator
GQ674_RS04815	COG3734	2-keto-3-deoxy-galactonokinase
GQ674_RS04820	COG3940	Belongs to the glycosyl hydrolase 43 family
GQ674_RS04835	COG3387	PFAM Glycoside hydrolase 15-related
GQ674_RS04855	COG2814	Major facilitator Superfamily
GQ674_RS04860	COG1942	4-Oxalocrotonate Tautomerase
GQ674_RS04875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQ674_RS04905	COG0745	RESPONSE REGULATOR receiver
GQ674_RS04925	COG4771	TonB-dependent receptor
GQ674_RS05065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS05080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GQ674_RS05110	COG3706	GGDEF domain
GQ674_RS05120	COG0588	phosphoglycerate mutase activity
GQ674_RS05130	COG3590	peptidase
GQ674_RS05145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQ674_RS05155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GQ674_RS05160	COG0745	RESPONSE REGULATOR receiver
GQ674_RS05165	COG2205	protein histidine kinase activity
GQ674_RS05170	COG4452	Inner membrane protein CreD
GQ674_RS05185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQ674_RS05190	COG0735	belongs to the Fur family
GQ674_RS05275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQ674_RS05290	COG5001	Diguanylate cyclase
GQ674_RS05290	COG5002	protein histidine kinase activity
GQ674_RS05295	COG0745	RESPONSE REGULATOR receiver
GQ674_RS05295	COG3706	GGDEF domain
GQ674_RS05300	COG1187	pseudouridine synthase activity
GQ674_RS05305	COG3706	GGDEF domain
GQ674_RS05310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQ674_RS05340	COG1132	(ABC) transporter
GQ674_RS05365	COG0583	DNA-binding transcription factor activity
GQ674_RS05410	COG0825	malonyl-CoA metabolic process
GQ674_RS05430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQ674_RS05435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQ674_RS05445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQ674_RS05450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQ674_RS05460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQ674_RS05465	COG0575	Belongs to the CDS family
GQ674_RS05470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQ674_RS05485	COG3706	GGDEF domain
GQ674_RS05500	COG0052	Belongs to the universal ribosomal protein uS2 family
GQ674_RS05515	COG3188	usher protein
GQ674_RS05530	COG0024	Methionine aminopeptidase
GQ674_RS05535	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GQ674_RS05545	COG1393	Belongs to the ArsC family
GQ674_RS05550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQ674_RS05565	COG0367	asparagine synthase
GQ674_RS05570	COG0475	glutathione-regulated potassium exporter activity
GQ674_RS05605	COG1566	PFAM secretion protein HlyD family protein
GQ674_RS05610	COG2814	Major facilitator Superfamily
GQ674_RS05635	COG0557	exoribonuclease II activity
GQ674_RS05645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQ674_RS05655	COG1136	(ABC) transporter
GQ674_RS05655	COG0577	efflux transmembrane transporter activity
GQ674_RS05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS05675	COG3706	GGDEF domain
GQ674_RS05680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQ674_RS05685	COG2259	Doxx family
GQ674_RS05695	COG3220	belongs to the UPF0276 family
GQ674_RS05705	COG0704	Plays a role in the regulation of phosphate uptake
GQ674_RS05710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GQ674_RS05715	COG0581	inorganic phosphate transmembrane transporter activity
GQ674_RS05720	COG0573	inorganic phosphate transmembrane transporter activity
GQ674_RS05725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GQ674_RS05730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GQ674_RS05745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQ674_RS05755	COG1024	Enoyl-CoA hydratase
GQ674_RS05785	COG0116	Belongs to the methyltransferase superfamily
GQ674_RS05785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQ674_RS05790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQ674_RS05815	COG1104	cysteine desulfurase activity
GQ674_RS05825	COG2733	membrane
GQ674_RS05840	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS05845	COG0477	Major facilitator Superfamily
GQ674_RS05850	COG2703	oxygen carrier activity
GQ674_RS05855	COG3706	GGDEF domain
GQ674_RS05855	COG0745	RESPONSE REGULATOR receiver
GQ674_RS05870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQ674_RS05875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQ674_RS05880	COG0174	glutamine synthetase
GQ674_RS05885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GQ674_RS05890	COG3842	ATPase activity
GQ674_RS05895	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQ674_RS05900	COG1177	transmembrane transport
GQ674_RS05905	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS05920	COG4535	Mg2 and Co2 transporter CorC
GQ674_RS05930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQ674_RS05935	COG1702	phosphate starvation-inducible protein PhoH
GQ674_RS05960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQ674_RS05965	COG0741	lytic transglycosylase activity
GQ674_RS05970	COG0723	plastoquinol--plastocyanin reductase activity
GQ674_RS05975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQ674_RS05980	COG2857	Cytochrome c1
GQ674_RS05985	COG0625	glutathione transferase activity
GQ674_RS05990	COG2969	positive regulation of protein catabolic process
GQ674_RS06030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GQ674_RS06035	COG0300	oxidoreductase activity
GQ674_RS06045	COG1611	Belongs to the LOG family
GQ674_RS06090	COG0556	nucleotide-excision repair
GQ674_RS06105	COG0811	peptide transport
GQ674_RS06120	COG1663	tetraacyldisaccharide 4'-kinase activity
GQ674_RS06125	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQ674_RS06135	COG0322	excinuclease ABC activity
GQ674_RS06140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQ674_RS06190	COG0348	domain, Protein
GQ674_RS06205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQ674_RS06245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQ674_RS06250	COG0069	glutamate synthase activity
GQ674_RS06280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQ674_RS06295	COG1253	flavin adenine dinucleotide binding
GQ674_RS06305	COG0306	phosphate transporter
GQ674_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQ674_RS06330	COG0504	CTP synthase activity
GQ674_RS06340	COG0148	phosphopyruvate hydratase activity
GQ674_RS06345	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GQ674_RS06350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GQ674_RS06355	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GQ674_RS06360	COG0585	pseudouridine synthase activity
GQ674_RS06365	COG2840	Smr protein MutS2
GQ674_RS06370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQ674_RS06375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQ674_RS06380	COG1238	metal cluster binding
GQ674_RS06395	COG1534	Rna-binding protein
GQ674_RS06400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GQ674_RS06405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQ674_RS06420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQ674_RS06425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQ674_RS06430	COG1923	regulation of RNA biosynthetic process
GQ674_RS06435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQ674_RS06440	COG1546	Belongs to the CinA family
GQ674_RS06445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQ674_RS06450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQ674_RS06460	COG2137	regulation of response to DNA damage stimulus
GQ674_RS06465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQ674_RS06470	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GQ674_RS06510	COG1741	Belongs to the pirin family
GQ674_RS06515	COG0583	DNA-binding transcription factor activity
GQ674_RS06545	COG0351	phosphomethylpyrimidine kinase
GQ674_RS06545	COG0352	thiamine-phosphate diphosphorylase activity
GQ674_RS06560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GQ674_RS06565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQ674_RS06575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQ674_RS06585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GQ674_RS06595	COG0477	Major facilitator Superfamily
GQ674_RS06605	COG0617	tRNA 3'-terminal CCA addition
GQ674_RS06615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQ674_RS06620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQ674_RS06630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQ674_RS06635	COG0166	Belongs to the GPI family
GQ674_RS06640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GQ674_RS06650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQ674_RS06655	COG0671	phosphoesterase, PA-phosphatase related
GQ674_RS06670	COG0129	dihydroxy-acid dehydratase activity
GQ674_RS06680	COG0837	glucose binding
GQ674_RS06685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GQ674_RS06690	COG3842	ATPase activity
GQ674_RS06705	COG2009	succinate dehydrogenase
GQ674_RS06710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GQ674_RS06720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQ674_RS06735	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQ674_RS06750	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GQ674_RS06760	COG0552	protein localization to endoplasmic reticulum
GQ674_RS06770	COG0326	Molecular chaperone. Has ATPase activity
GQ674_RS06780	COG0742	ribosomal rna small subunit methyltransferase
GQ674_RS06785	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQ674_RS06795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQ674_RS06800	COG0405	Gamma-glutamyltransferase
GQ674_RS06805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQ674_RS06815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQ674_RS06835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQ674_RS06890	COG0415	Belongs to the DNA photolyase family
GQ674_RS06895	COG2885	chlorophyll binding
GQ674_RS06895	COG3047	cAMP biosynthetic process
GQ674_RS06905	COG0583	DNA-binding transcription factor activity
GQ674_RS07000	COG1397	ADP-ribosylglycohydrolase
GQ674_RS07030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQ674_RS07045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQ674_RS07050	COG0735	belongs to the Fur family
GQ674_RS07060	COG0583	DNA-binding transcription factor activity
GQ674_RS07065	COG0497	DNA recombination
GQ674_RS07070	COG1420	regulation of RNA biosynthetic process
GQ674_RS07075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQ674_RS07080	COG0443	Heat shock 70 kDa protein
GQ674_RS07085	COG0484	heat shock protein binding
GQ674_RS07090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GQ674_RS07105	COG1132	(ABC) transporter
GQ674_RS07120	COG1595	DNA-templated transcription, initiation
GQ674_RS07125	COG5001	Diguanylate cyclase
GQ674_RS07135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQ674_RS07140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQ674_RS07150	COG1862	Preprotein translocase
GQ674_RS07160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQ674_RS07165	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQ674_RS07180	COG1309	transcriptional regulator
GQ674_RS07190	COG2081	HI0933 family
GQ674_RS07195	COG4681	YaeQ
GQ674_RS07205	COG0564	pseudouridine synthase activity
GQ674_RS07220	COG0625	glutathione transferase activity
GQ674_RS07230	COG3420	alginic acid biosynthetic process
GQ674_RS07240	COG0710	3-dehydroquinate dehydratase activity
GQ674_RS07255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GQ674_RS07265	COG3485	protocatechuate 3,4-dioxygenase
GQ674_RS07270	COG3485	protocatechuate 3,4-dioxygenase
GQ674_RS07280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQ674_RS07285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQ674_RS07290	COG1414	Transcriptional regulator
GQ674_RS07305	COG0513	Belongs to the DEAD box helicase family
GQ674_RS07320	COG0583	DNA-binding transcription factor activity
GQ674_RS07350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS07365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQ674_RS07370	COG2957	Belongs to the agmatine deiminase family
GQ674_RS07380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQ674_RS07385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQ674_RS07390	COG0539	negative regulation of cytoplasmic translation
GQ674_RS07395	COG0776	regulation of translation
GQ674_RS07405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GQ674_RS07420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQ674_RS07425	COG0183	Belongs to the thiolase family
GQ674_RS07430	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQ674_RS07430	COG1024	Enoyl-CoA hydratase
GQ674_RS07440	COG0105	UTP biosynthetic process
GQ674_RS07455	COG1426	Protein conserved in bacteria
GQ674_RS07465	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQ674_RS07470	COG1160	GTP binding
GQ674_RS07480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQ674_RS07480	COG0475	glutathione-regulated potassium exporter activity
GQ674_RS07495	COG0519	Catalyzes the synthesis of GMP from XMP
GQ674_RS07495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQ674_RS07520	COG0583	DNA-binding transcription factor activity
GQ674_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS07550	COG0431	NADPH-dependent FMN reductase
GQ674_RS07555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQ674_RS07565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQ674_RS07570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQ674_RS07575	COG1473	amidohydrolase
GQ674_RS07605	COG0583	DNA-binding transcription factor activity
GQ674_RS07670	COG0697	spore germination
GQ674_RS07675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQ674_RS07680	COG0167	dihydroorotate dehydrogenase activity
GQ674_RS07695	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS07700	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS07705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQ674_RS07710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQ674_RS07720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQ674_RS07755	COG1215	transferase activity, transferring glycosyl groups
GQ674_RS07765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQ674_RS07810	COG1063	alcohol dehydrogenase
GQ674_RS07870	COG0527	aspartate kinase activity
GQ674_RS07870	COG0460	homoserine dehydrogenase
GQ674_RS07885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQ674_RS07890	COG0124	histidyl-tRNA synthetase
GQ674_RS07910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQ674_RS07915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQ674_RS07925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQ674_RS07930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQ674_RS07935	COG0107	imidazoleglycerol-phosphate synthase activity
GQ674_RS07940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQ674_RS07940	COG0140	phosphoribosyl-ATP diphosphatase activity
GQ674_RS07955	COG1446	asparaginase
GQ674_RS07960	COG3142	Participates in the control of copper homeostasis
GQ674_RS07970	COG3537	Alpha-1,2-mannosidase
GQ674_RS07985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQ674_RS08000	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GQ674_RS08005	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GQ674_RS08010	COG0235	Class ii aldolase
GQ674_RS08015	COG0531	amino acid
GQ674_RS08020	COG0531	amino acid
GQ674_RS08030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQ674_RS08035	COG0277	FAD linked oxidase domain protein
GQ674_RS08050	COG5002	protein histidine kinase activity
GQ674_RS08055	COG0745	RESPONSE REGULATOR receiver
GQ674_RS08065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS08080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQ674_RS08105	COG1024	Enoyl-CoA hydratase
GQ674_RS08115	COG1918	ferrous iron import across plasma membrane
GQ674_RS08115	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQ674_RS08125	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQ674_RS08130	COG0789	Transcriptional regulator
GQ674_RS08135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQ674_RS08140	COG0505	Belongs to the CarA family
GQ674_RS08145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQ674_RS08150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQ674_RS08165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQ674_RS08175	COG4676	Protein conserved in bacteria
GQ674_RS08185	COG0501	Belongs to the peptidase M48B family
GQ674_RS08195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQ674_RS08205	COG2205	protein histidine kinase activity
GQ674_RS08205	COG0784	Response regulator, receiver
GQ674_RS08205	COG2198	Histidine kinase
GQ674_RS08210	COG1024	Enoyl-CoA hydratase
GQ674_RS08215	COG0318	PFAM AMP-dependent synthetase and ligase
GQ674_RS08245	COG2201	protein-glutamate methylesterase activity
GQ674_RS08250	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GQ674_RS08260	COG0840	transmembrane signaling receptor activity
GQ674_RS08265	COG0840	transmembrane signaling receptor activity
GQ674_RS08275	COG0835	chemotaxis
GQ674_RS08280	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GQ674_RS08285	COG0840	transmembrane signaling receptor activity
GQ674_RS08295	COG0745	RESPONSE REGULATOR receiver
GQ674_RS08310	COG1192	Involved in chromosome partitioning
GQ674_RS08315	COG1360	Flagellar Motor Protein
GQ674_RS08320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQ674_RS08325	COG0643	Histidine kinase
GQ674_RS08325	COG2198	Histidine kinase
GQ674_RS08330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GQ674_RS08345	COG0455	bacterial-type flagellum organization
GQ674_RS08355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GQ674_RS08360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GQ674_RS08380	COG0542	response to heat
GQ674_RS08395	COG1987	bacterial-type flagellum assembly
GQ674_RS08405	COG3190	flagellar
GQ674_RS08460	COG3604	Transcriptional regulator
GQ674_RS08465	COG2197	response regulator
GQ674_RS08470	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GQ674_RS08475	COG2197	response regulator
GQ674_RS08540	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GQ674_RS08545	COG4786	Flagellar basal body rod
GQ674_RS08550	COG4787	bacterial-type flagellum-dependent cell motility
GQ674_RS08555	COG1749	Flagellar hook protein flgE
GQ674_RS08565	COG1558	bacterial-type flagellum-dependent cell motility
GQ674_RS08575	COG0784	Response regulator, receiver
GQ674_RS08575	COG0835	chemotaxis
GQ674_RS08595	COG5002	protein histidine kinase activity
GQ674_RS08635	COG2915	High frequency lysogenization protein hflD homolog
GQ674_RS08640	COG0482	sulfurtransferase activity
GQ674_RS08655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GQ674_RS08665	COG0542	response to heat
GQ674_RS08675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQ674_RS08680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GQ674_RS08690	COG0492	ferredoxin-NADP+ reductase activity
GQ674_RS08695	COG1674	ftsk spoiiie
GQ674_RS08710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQ674_RS08715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQ674_RS08725	COG2205	protein histidine kinase activity
GQ674_RS08725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQ674_RS08735	COG0583	DNA-binding transcription factor activity
GQ674_RS08745	COG0625	glutathione transferase activity
GQ674_RS08755	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQ674_RS08770	COG2819	hydrolase of the alpha beta superfamily
GQ674_RS08780	COG4558	Periplasmic binding protein
GQ674_RS08785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQ674_RS08790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQ674_RS08795	COG4774	siderophore transport
GQ674_RS08805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQ674_RS08815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQ674_RS08820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQ674_RS08825	COG0840	transmembrane signaling receptor activity
GQ674_RS08835	COG0477	Major facilitator Superfamily
GQ674_RS08840	COG3537	Alpha-1,2-mannosidase
GQ674_RS08870	COG2223	nitrite transmembrane transporter activity
GQ674_RS08905	COG0318	PFAM AMP-dependent synthetase and ligase
GQ674_RS08920	COG0642	Histidine kinase
GQ674_RS08930	COG0596	Alpha beta hydrolase
GQ674_RS08940	COG2610	gluconate transmembrane transporter activity
GQ674_RS08990	COG1070	Carbohydrate kinase
GQ674_RS09000	COG0477	Major facilitator Superfamily
GQ674_RS09015	COG3661	Belongs to the glycosyl hydrolase 67 family
GQ674_RS09030	COG1472	Belongs to the glycosyl hydrolase 3 family
GQ674_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS09055	COG3459	Glycosyltransferase 36 associated
GQ674_RS09070	COG0583	DNA-binding transcription factor activity
GQ674_RS09085	COG0642	Histidine kinase
GQ674_RS09090	COG0745	RESPONSE REGULATOR receiver
GQ674_RS09100	COG0300	oxidoreductase activity
GQ674_RS09110	COG1022	Amp-dependent synthetase and ligase
GQ674_RS09175	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS09290	COG2204	response regulator
GQ674_RS09320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQ674_RS09325	COG1285	pathogenesis
GQ674_RS09330	COG4191	Histidine kinase
GQ674_RS09335	COG4566	intracellular signal transduction
GQ674_RS09345	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS09350	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GQ674_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQ674_RS09360	COG1535	isochorismatase
GQ674_RS09360	COG3433	isochorismatase activity
GQ674_RS09365	COG1021	2,3-dihydroxybenzoate-AMP ligase
GQ674_RS09370	COG1169	isochorismate synthase
GQ674_RS09380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQ674_RS09385	COG0471	metal ion transport
GQ674_RS09390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQ674_RS09395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQ674_RS09400	COG0716	FMN binding
GQ674_RS09410	COG2409	Drug exporters of the RND superfamily
GQ674_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS09420	COG0583	DNA-binding transcription factor activity
GQ674_RS09430	COG2223	nitrite transmembrane transporter activity
GQ674_RS09495	COG2814	Major facilitator Superfamily
GQ674_RS09505	COG1228	amidohydrolase
GQ674_RS09515	COG1335	isochorismatase
GQ674_RS09520	COG2207	Transcriptional regulator
GQ674_RS09520	COG3708	Transcriptional regulator
GQ674_RS09530	COG4585	Histidine kinase
GQ674_RS09535	COG2197	response regulator
GQ674_RS09540	COG2814	Major facilitator Superfamily
GQ674_RS09550	COG1914	H( )-stimulated, divalent metal cation uptake system
GQ674_RS09575	COG1999	signal sequence binding
GQ674_RS09585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GQ674_RS09590	COG1845	cytochrome c oxidase, subunit III
GQ674_RS09595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQ674_RS09600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQ674_RS09605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQ674_RS09615	COG1733	regulation of RNA biosynthetic process
GQ674_RS09630	COG0604	alcohol dehydrogenase
GQ674_RS09635	COG1309	transcriptional regulator
GQ674_RS09695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GQ674_RS09735	COG4964	Belongs to the GSP D family
GQ674_RS09790	COG0456	acetyltransferase
GQ674_RS09795	COG4771	TonB-dependent receptor
GQ674_RS09830	COG3501	Rhs element vgr protein
GQ674_RS09860	COG3501	Rhs element vgr protein
GQ674_RS09885	COG3501	Rhs element vgr protein
GQ674_RS09895	COG2885	chlorophyll binding
GQ674_RS09985	COG3501	Rhs element vgr protein
GQ674_RS10050	COG3501	Rhs element vgr protein
GQ674_RS10060	COG1388	LysM domain
GQ674_RS10060	COG0741	lytic transglycosylase activity
GQ674_RS10085	COG0277	FAD linked oxidase domain protein
GQ674_RS10090	COG1304	FMN binding
GQ674_RS10095	COG2186	Transcriptional regulator
GQ674_RS10120	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS10145	COG0477	Major facilitator Superfamily
GQ674_RS10155	COG1472	Belongs to the glycosyl hydrolase 3 family
GQ674_RS10165	COG2814	Major facilitator Superfamily
GQ674_RS10180	COG0587	DNA-directed DNA polymerase activity
GQ674_RS10215	COG0583	DNA-binding transcription factor activity
GQ674_RS10240	COG0251	oxidation-reduction process
GQ674_RS10255	COG1733	regulation of RNA biosynthetic process
GQ674_RS10260	COG0625	glutathione transferase activity
GQ674_RS10275	COG3275	phosphorelay sensor kinase activity
GQ674_RS10285	COG0024	Methionine aminopeptidase
GQ674_RS10310	COG1982	Orn Lys Arg decarboxylase major
GQ674_RS10315	COG0531	amino acid
GQ674_RS10320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GQ674_RS10330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS10340	COG0789	Transcriptional regulator
GQ674_RS10410	COG2197	response regulator
GQ674_RS10415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQ674_RS10415	COG2205	protein histidine kinase activity
GQ674_RS10430	COG5002	protein histidine kinase activity
GQ674_RS10430	COG3447	MASE1 domain protein
GQ674_RS10430	COG5001	Diguanylate cyclase
GQ674_RS10435	COG2183	response to ionizing radiation
GQ674_RS10450	COG1983	PspC domain protein
GQ674_RS10460	COG3243	poly(R)-hydroxyalkanoic acid synthase
GQ674_RS10490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GQ674_RS10500	COG1943	Transposase
GQ674_RS10505	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS10515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GQ674_RS10520	COG0590	tRNA wobble adenosine to inosine editing
GQ674_RS10525	COG1321	iron dependent repressor
GQ674_RS10530	COG3437	response regulator, receiver
GQ674_RS10530	COG4999	Histidine kinase
GQ674_RS10530	COG3850	Histidine kinase
GQ674_RS10530	COG2205	protein histidine kinase activity
GQ674_RS10535	COG2201	protein-glutamate methylesterase activity
GQ674_RS10540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GQ674_RS10550	COG0784	Response regulator, receiver
GQ674_RS10550	COG4191	Histidine kinase
GQ674_RS10570	COG2814	Major facilitator Superfamily
GQ674_RS10580	COG0210	DNA helicase
GQ674_RS10600	COG1201	RNA secondary structure unwinding
GQ674_RS10625	COG4191	Histidine kinase
GQ674_RS10625	COG0784	Response regulator, receiver
GQ674_RS10630	COG2205	protein histidine kinase activity
GQ674_RS10640	COG2172	sigma factor antagonist activity
GQ674_RS10645	COG1366	Belongs to the anti-sigma-factor antagonist family
GQ674_RS10650	COG1366	Belongs to the anti-sigma-factor antagonist family
GQ674_RS10675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQ674_RS10680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQ674_RS10730	COG0745	RESPONSE REGULATOR receiver
GQ674_RS10735	COG2205	protein histidine kinase activity
GQ674_RS10745	COG2194	sulfuric ester hydrolase activity
GQ674_RS10775	COG2814	Major facilitator Superfamily
GQ674_RS10780	COG0583	DNA-binding transcription factor activity
GQ674_RS10790	COG3685	Protein conserved in bacteria
GQ674_RS10805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQ674_RS10830	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS10840	COG2267	carboxylic ester hydrolase activity
GQ674_RS10845	COG0604	alcohol dehydrogenase
GQ674_RS10865	COG5001	Diguanylate cyclase
GQ674_RS10865	COG3300	MHYT domain
GQ674_RS10880	COG4774	siderophore transport
GQ674_RS10890	COG5001	Diguanylate cyclase
GQ674_RS10890	COG3300	MHYT domain
GQ674_RS10895	COG0840	transmembrane signaling receptor activity
GQ674_RS10920	COG3279	Response regulator of the LytR AlgR family
GQ674_RS10925	COG3275	phosphorelay sensor kinase activity
GQ674_RS10935	COG2207	Transcriptional regulator
GQ674_RS10970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQ674_RS10985	COG0583	DNA-binding transcription factor activity
GQ674_RS11025	COG2200	EAL domain
GQ674_RS11030	COG2197	response regulator
GQ674_RS11040	COG5001	Diguanylate cyclase
GQ674_RS11040	COG3300	MHYT domain
GQ674_RS11045	COG3706	GGDEF domain
GQ674_RS11050	COG0840	transmembrane signaling receptor activity
GQ674_RS11055	COG4191	Histidine kinase
GQ674_RS11055	COG0784	Response regulator, receiver
GQ674_RS11105	COG0583	DNA-binding transcription factor activity
GQ674_RS11110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GQ674_RS11120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQ674_RS11135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQ674_RS11140	COG0077	Prephenate dehydratase
GQ674_RS11140	COG1605	Chorismate mutase
GQ674_RS11145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQ674_RS11180	COG1228	amidohydrolase
GQ674_RS11185	COG2986	histidine ammonia-lyase
GQ674_RS11195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQ674_RS11275	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQ674_RS11310	COG4993	Dehydrogenase
GQ674_RS11320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQ674_RS11330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GQ674_RS11340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQ674_RS11345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQ674_RS11360	COG0359	binds to the 23S rRNA
GQ674_RS11365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQ674_RS11370	COG0360	Binds together with S18 to 16S ribosomal RNA
GQ674_RS11375	COG0316	Belongs to the HesB IscA family
GQ674_RS11380	COG0017	Asparaginyl-tRNA synthetase
GQ674_RS11400	COG0288	reversible hydration of carbon dioxide
GQ674_RS11410	COG3844	kynureninase activity
GQ674_RS11415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQ674_RS11420	COG2925	Exonuclease
GQ674_RS11430	COG0667	Aldo Keto reductase
GQ674_RS11450	COG2902	Dehydrogenase
GQ674_RS11465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS11475	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS11490	COG1410	methionine synthase
GQ674_RS11490	COG0646	methionine synthase
GQ674_RS11525	COG0386	Belongs to the glutathione peroxidase family
GQ674_RS11535	COG1725	Transcriptional regulator
GQ674_RS11540	COG1131	(ABC) transporter
GQ674_RS11570	COG1253	flavin adenine dinucleotide binding
GQ674_RS11580	COG2850	peptidyl-arginine hydroxylation
GQ674_RS11590	COG0567	Dehydrogenase, E1 component
GQ674_RS11620	COG0305	Participates in initiation and elongation during chromosome replication
GQ674_RS11630	COG0367	asparagine synthase
GQ674_RS11635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQ674_RS11655	COG0084	hydrolase, TatD family'
GQ674_RS11660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQ674_RS11705	COG1280	lysine exporter protein (LysE YggA)
GQ674_RS11715	COG1595	DNA-templated transcription, initiation
GQ674_RS11720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GQ674_RS11740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS11745	COG0386	Belongs to the glutathione peroxidase family
GQ674_RS11750	COG0339	signal peptide processing
GQ674_RS11765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQ674_RS11815	COG0316	Belongs to the HesB IscA family
GQ674_RS11815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GQ674_RS11820	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQ674_RS11830	COG0428	transporter
GQ674_RS11835	COG0564	pseudouridine synthase activity
GQ674_RS11840	COG1530	ribonuclease E activity
GQ674_RS11860	COG0395	ABC-type sugar transport system, permease component
GQ674_RS11895	COG2350	Protein conserved in bacteria
GQ674_RS11900	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GQ674_RS11905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GQ674_RS11910	COG1187	pseudouridine synthase activity
GQ674_RS11925	COG0436	Aminotransferase
GQ674_RS11950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GQ674_RS11955	COG1138	Cytochrome C-type biogenesis protein
GQ674_RS11960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS11975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQ674_RS12020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GQ674_RS12025	COG4988	ABC transporter
GQ674_RS12030	COG1271	oxidase subunit
GQ674_RS12035	COG1294	oxidase, subunit
GQ674_RS12065	COG0726	polysaccharide deacetylase
GQ674_RS12065	COG1649	PFAM Uncharacterised BCR, COG1649
GQ674_RS12070	COG1215	transferase activity, transferring glycosyl groups
GQ674_RS12085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQ674_RS12095	COG0165	Argininosuccinate lyase
GQ674_RS12100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQ674_RS12110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQ674_RS12115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQ674_RS12120	COG0137	argininosuccinate synthase activity
GQ674_RS12125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQ674_RS12140	COG2166	iron-sulfur cluster assembly
GQ674_RS12150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQ674_RS12160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQ674_RS12180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQ674_RS12185	COG0402	S-adenosylhomocysteine deaminase activity
GQ674_RS12195	COG1509	lysine 2,3-aminomutase activity
GQ674_RS12200	COG3300	MHYT domain
GQ674_RS12200	COG5001	Diguanylate cyclase
GQ674_RS12215	COG0483	inositol monophosphate 1-phosphatase activity
GQ674_RS12220	COG0501	Belongs to the peptidase M48B family
GQ674_RS12230	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS12255	COG0860	N-Acetylmuramoyl-L-alanine amidase
GQ674_RS12260	COG0802	atpase or kinase
GQ674_RS12265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQ674_RS12265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GQ674_RS12270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQ674_RS12275	COG1570	exodeoxyribonuclease VII activity
GQ674_RS12285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQ674_RS12300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQ674_RS12315	COG4771	TonB-dependent receptor
GQ674_RS12320	COG0840	transmembrane signaling receptor activity
GQ674_RS12330	COG0582	viral genome integration into host DNA
GQ674_RS12440	COG2130	NADP-dependent
GQ674_RS12460	COG0477	Major facilitator Superfamily
GQ674_RS12480	COG1473	amidohydrolase
GQ674_RS12485	COG3964	amidohydrolase
GQ674_RS12510	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS12520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQ674_RS12555	COG2205	protein histidine kinase activity
GQ674_RS12560	COG0745	RESPONSE REGULATOR receiver
GQ674_RS12565	COG3713	MltA-interacting MipA family protein
GQ674_RS12585	COG5487	UPF0391 membrane protein
GQ674_RS12600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQ674_RS12620	COG2076	Multidrug Resistance protein
GQ674_RS12625	COG1309	transcriptional regulator
GQ674_RS12730	COG0740	serine-type endopeptidase activity
GQ674_RS12860	COG0776	regulation of translation
GQ674_RS12870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQ674_RS12875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQ674_RS12880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQ674_RS12885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQ674_RS12890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQ674_RS12935	COG1185	polyribonucleotide nucleotidyltransferase activity
GQ674_RS12940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQ674_RS12950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQ674_RS12955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQ674_RS12960	COG0195	Participates in both transcription termination and antitermination
GQ674_RS12965	COG0779	Required for maturation of 30S ribosomal subunits
GQ674_RS12980	COG1007	ATP synthesis coupled electron transport
GQ674_RS12995	COG0713	ATP synthesis coupled electron transport
GQ674_RS13010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQ674_RS13015	COG1034	ATP synthesis coupled electron transport
GQ674_RS13020	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQ674_RS13025	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GQ674_RS13030	COG0649	NAD binding
GQ674_RS13035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQ674_RS13040	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQ674_RS13045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQ674_RS13060	COG0149	triose-phosphate isomerase activity
GQ674_RS13070	COG3083	sulfuric ester hydrolase activity
GQ674_RS13075	COG0297	glycogen (starch) synthase activity
GQ674_RS13080	COG0726	polysaccharide deacetylase
GQ674_RS13085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQ674_RS13090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQ674_RS13095	COG0159	tryptophan synthase activity
GQ674_RS13105	COG0133	tryptophan synthase activity
GQ674_RS13140	COG0135	phosphoribosylanthranilate isomerase activity
GQ674_RS13145	COG0101	tRNA pseudouridine synthase activity
GQ674_RS13160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQ674_RS13170	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQ674_RS13175	COG2890	protein-(glutamine-N5) methyltransferase activity
GQ674_RS13180	COG1999	signal sequence binding
GQ674_RS13185	COG0688	phosphatidylethanolamine metabolic process
GQ674_RS13200	COG0433	COG0433 Predicted ATPase
GQ674_RS13205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQ674_RS13215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQ674_RS13230	COG0717	Belongs to the dCTP deaminase family
GQ674_RS13235	COG0489	protein tyrosine kinase activity
GQ674_RS13260	COG3590	peptidase
GQ674_RS13280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQ674_RS13295	COG2311	Membrane
GQ674_RS13305	COG0791	NLP P60 protein
GQ674_RS13310	COG0791	NLP P60 protein
GQ674_RS13350	COG1301	dicarboxylic acid transport
GQ674_RS13370	COG1722	exodeoxyribonuclease VII activity
GQ674_RS13375	COG0142	geranyltranstransferase activity
GQ674_RS13385	COG0312	modulator of DNA gyrase
GQ674_RS13390	COG3028	Belongs to the UPF0307 family
GQ674_RS13395	COG0312	modulator of DNA gyrase
GQ674_RS13405	COG1530	ribonuclease E activity
GQ674_RS13410	COG0424	maF-like protein
GQ674_RS13415	COG2968	Membrane
GQ674_RS13440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GQ674_RS13450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQ674_RS13465	COG0495	leucyl-tRNA aminoacylation
GQ674_RS13480	COG3118	belongs to the thioredoxin family
GQ674_RS13490	COG2203	Gaf domain
GQ674_RS13490	COG4251	negative regulation of phosphorylation
GQ674_RS13490	COG5001	Diguanylate cyclase
GQ674_RS13490	COG3706	GGDEF domain
GQ674_RS13515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GQ674_RS13530	COG0346	lactoylglutathione lyase activity
GQ674_RS13540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQ674_RS13540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQ674_RS13550	COG2878	Part of a membrane complex involved in electron transport
GQ674_RS13555	COG0251	oxidation-reduction process
GQ674_RS13560	COG0392	lysyltransferase activity
GQ674_RS13560	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQ674_RS13590	COG2824	Alkylphosphonate utilization operon protein PhnA
GQ674_RS13635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQ674_RS13640	COG3122	Protein conserved in bacteria
GQ674_RS13645	COG1451	nucleotide metabolic process
GQ674_RS13655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQ674_RS13675	COG0183	Belongs to the thiolase family
GQ674_RS13690	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS13700	COG1793	dna ligase
GQ674_RS13705	COG1201	RNA secondary structure unwinding
GQ674_RS13720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQ674_RS13725	COG1278	Cold shock
GQ674_RS13730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQ674_RS13740	COG1472	Belongs to the glycosyl hydrolase 3 family
GQ674_RS13745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GQ674_RS13760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQ674_RS13765	COG0745	RESPONSE REGULATOR receiver
GQ674_RS13770	COG1381	Involved in DNA repair and RecF pathway recombination
GQ674_RS13775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQ674_RS13790	COG0681	Belongs to the peptidase S26 family
GQ674_RS13795	COG0481	GTPase activity
GQ674_RS13800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQ674_RS13815	COG1024	Enoyl-CoA hydratase
GQ674_RS13815	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQ674_RS13820	COG1741	Belongs to the pirin family
GQ674_RS13825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQ674_RS13835	COG1741	Belongs to the pirin family
GQ674_RS13840	COG1966	Carbon starvation protein
GQ674_RS13845	COG2879	small protein
GQ674_RS13860	COG2205	protein histidine kinase activity
GQ674_RS13880	COG2194	sulfuric ester hydrolase activity
GQ674_RS13895	COG2814	Major facilitator Superfamily
GQ674_RS13900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQ674_RS13900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQ674_RS13905	COG1113	amino acid transport
GQ674_RS13910	COG2207	Transcriptional regulator
GQ674_RS13910	COG1917	Cupin 2, conserved barrel domain protein
GQ674_RS13915	COG0753	catalase activity
GQ674_RS13935	COG0840	transmembrane signaling receptor activity
GQ674_RS13940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQ674_RS13950	COG0330	HflC and HflK could
GQ674_RS13955	COG0330	HflC and HflK could
GQ674_RS13960	COG0604	alcohol dehydrogenase
GQ674_RS13975	COG0678	peroxiredoxin activity
GQ674_RS13985	COG4953	penicillin-binding protein 1C
GQ674_RS13990	COG2373	Large extracellular alpha-helical protein
GQ674_RS14000	COG2828	Protein conserved in bacteria
GQ674_RS14010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQ674_RS14025	COG3829	transcription factor binding
GQ674_RS14035	COG0259	pyridoxamine-phosphate oxidase activity
GQ674_RS14050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQ674_RS14075	COG2814	Major facilitator Superfamily
GQ674_RS14095	COG2205	protein histidine kinase activity
GQ674_RS14095	COG0784	Response regulator, receiver
GQ674_RS14095	COG2198	Histidine kinase
GQ674_RS14105	COG3038	cytochrome b561
GQ674_RS14110	COG2353	YceI-like domain
GQ674_RS14120	COG1760	l-serine dehydratase
GQ674_RS14125	COG0596	Alpha beta hydrolase
GQ674_RS14125	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQ674_RS14130	COG0527	aspartate kinase activity
GQ674_RS14130	COG0460	homoserine dehydrogenase
GQ674_RS14135	COG0626	cystathionine gamma-synthase activity
GQ674_RS14140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQ674_RS14145	COG0739	heme binding
GQ674_RS14150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GQ674_RS14155	COG1272	protein, Hemolysin III
GQ674_RS14160	COG2982	Protein involved in outer membrane biogenesis
GQ674_RS14170	COG0463	Glycosyl transferase, family 2
GQ674_RS14180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GQ674_RS14200	COG1309	transcriptional regulator
GQ674_RS14210	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS14250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQ674_RS14260	COG0330	HflC and HflK could
GQ674_RS14270	COG3956	TIGRFAM MazG family protein
GQ674_RS14275	COG1218	3'(2'),5'-bisphosphate nucleotidase
GQ674_RS14280	COG0494	nUDIX hydrolase
GQ674_RS14290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQ674_RS14310	COG0840	transmembrane signaling receptor activity
GQ674_RS14315	COG0835	chemotaxis
GQ674_RS14330	COG0189	ligase activity
GQ674_RS14345	COG1199	ATP-dependent helicase activity
GQ674_RS14355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQ674_RS14375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQ674_RS14385	COG1643	Atp-dependent helicase
GQ674_RS14390	COG0783	Belongs to the Dps family
GQ674_RS14395	COG0514	ATP-dependent DNA helicase (RecQ)
GQ674_RS14430	COG3279	Response regulator of the LytR AlgR family
GQ674_RS14505	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GQ674_RS14510	COG0602	queuosine metabolic process
GQ674_RS14520	COG2885	chlorophyll binding
GQ674_RS14525	COG0823	Involved in the tonB-independent uptake of proteins
GQ674_RS14550	COG0824	Thioesterase
GQ674_RS14555	COG2255	four-way junction helicase activity
GQ674_RS14565	COG0632	four-way junction helicase activity
GQ674_RS14570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQ674_RS14575	COG0217	transcriptional regulatory protein
GQ674_RS14580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GQ674_RS14595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQ674_RS14630	COG0488	(ABC) transporter
GQ674_RS14635	COG4206	TonB-dependent receptor
GQ674_RS14640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQ674_RS14640	COG4651	solute:proton antiporter activity
GQ674_RS14655	COG0542	response to heat
GQ674_RS14660	COG1595	DNA-templated transcription, initiation
GQ674_RS14675	COG1858	cytochrome C peroxidase
GQ674_RS14695	COG0028	Belongs to the TPP enzyme family
GQ674_RS14730	COG3387	PFAM Glycoside hydrolase 15-related
GQ674_RS14735	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GQ674_RS14755	COG0564	pseudouridine synthase activity
GQ674_RS14760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQ674_RS14770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQ674_RS14770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQ674_RS14780	COG0045	succinate-CoA ligase (ADP-forming) activity
GQ674_RS14820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GQ674_RS14830	COG2205	protein histidine kinase activity
GQ674_RS14835	COG0745	RESPONSE REGULATOR receiver
GQ674_RS14845	COG0189	ligase activity
GQ674_RS15020	COG5001	Diguanylate cyclase
GQ674_RS15020	COG3300	MHYT domain
GQ674_RS15045	COG2022	thiamine diphosphate biosynthetic process
GQ674_RS15050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQ674_RS15055	COG0471	metal ion transport
GQ674_RS15055	COG3273	potassium ion transport
GQ674_RS15070	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQ674_RS15075	COG1970	mechanosensitive ion channel activity
GQ674_RS15085	COG1115	amino acid carrier protein
GQ674_RS15100	COG1115	amino acid carrier protein
GQ674_RS15105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS15110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS15135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GQ674_RS15155	COG3588	fructose-bisphosphate aldolase
GQ674_RS15160	COG0469	pyruvate kinase activity
GQ674_RS15170	COG0126	phosphoglycerate kinase activity
GQ674_RS15185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQ674_RS15190	COG3047	cAMP biosynthetic process
GQ674_RS15195	COG1794	racemase activity, acting on amino acids and derivatives
GQ674_RS15205	COG3453	Protein conserved in bacteria
GQ674_RS15205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQ674_RS15235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQ674_RS15240	COG1301	dicarboxylic acid transport
GQ674_RS15270	COG0714	Associated with various cellular activities
GQ674_RS15300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GQ674_RS15365	COG0515	serine threonine protein kinase
GQ674_RS15395	COG0254	rRNA binding
GQ674_RS15400	COG1957	nucleoside hydrolase
GQ674_RS15405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQ674_RS15415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQ674_RS15420	COG1758	RNA polymerase activity
GQ674_RS15430	COG1561	YicC-like family, N-terminal region
GQ674_RS15435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQ674_RS15440	COG0346	lactoylglutathione lyase activity
GQ674_RS15445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQ674_RS15450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQ674_RS15465	COG0006	proline dipeptidase activity
GQ674_RS15470	COG0006	proline dipeptidase activity
GQ674_RS15495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQ674_RS15505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQ674_RS15515	COG2912	Transglutaminase-like superfamily
GQ674_RS15520	COG1773	rubredoxin
GQ674_RS15530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQ674_RS15535	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GQ674_RS15545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQ674_RS15550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQ674_RS15565	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS15600	COG0671	phosphoesterase, PA-phosphatase related
GQ674_RS15610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQ674_RS15615	COG0563	adenylate kinase activity
GQ674_RS15640	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GQ674_RS15650	COG0848	biopolymer transport protein
GQ674_RS15660	COG2832	Protein of unknown function (DUF454)
GQ674_RS15695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQ674_RS15725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQ674_RS15730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQ674_RS15735	COG0405	Gamma-glutamyltransferase
GQ674_RS15740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQ674_RS15760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQ674_RS15765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQ674_RS15770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQ674_RS15780	COG0473	3-isopropylmalate dehydrogenase activity
GQ674_RS15785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQ674_RS15815	COG1538	Outer membrane efflux protein
GQ674_RS15825	COG2239	Acts as a magnesium transporter
GQ674_RS15830	COG1519	Transferase
GQ674_RS15835	COG1560	Kdo2-lipid A biosynthetic process
GQ674_RS15870	COG1301	dicarboxylic acid transport
GQ674_RS15880	COG4191	Histidine kinase
GQ674_RS15895	COG1840	ABC-type Fe3 transport system, periplasmic component
GQ674_RS15900	COG0642	Histidine kinase
GQ674_RS15915	COG2851	Citrate transporter
GQ674_RS15920	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS15940	COG1162	GTPase activity
GQ674_RS15945	COG0436	Aminotransferase
GQ674_RS15970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GQ674_RS15990	COG3964	amidohydrolase
GQ674_RS15995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQ674_RS16005	COG1307	EDD domain protein, DegV family
GQ674_RS16045	COG5001	Diguanylate cyclase
GQ674_RS16045	COG4251	negative regulation of phosphorylation
GQ674_RS16045	COG2203	Gaf domain
GQ674_RS16045	COG3706	GGDEF domain
GQ674_RS16050	COG1376	ErfK ybiS ycfS ynhG family protein
GQ674_RS16055	COG0739	heme binding
GQ674_RS16105	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS16120	COG0583	DNA-binding transcription factor activity
GQ674_RS16125	COG1064	alcohol dehydrogenase
GQ674_RS16145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQ674_RS16150	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQ674_RS16165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQ674_RS16175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQ674_RS16190	COG5006	permease, DMT superfamily
GQ674_RS16195	COG1522	sequence-specific DNA binding
GQ674_RS16210	COG4773	Receptor
GQ674_RS16215	COG1280	lysine exporter protein (LysE YggA)
GQ674_RS16220	COG4206	TonB-dependent receptor
GQ674_RS16240	COG0617	tRNA 3'-terminal CCA addition
GQ674_RS16260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQ674_RS16265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQ674_RS16270	COG1609	Transcriptional regulator
GQ674_RS16280	COG0837	glucose binding
GQ674_RS16290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQ674_RS16325	COG0784	Response regulator, receiver
GQ674_RS16330	COG4251	negative regulation of phosphorylation
GQ674_RS16335	COG2823	Periplasmic or secreted lipoprotein
GQ674_RS16340	COG0673	inositol 2-dehydrogenase activity
GQ674_RS16345	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GQ674_RS16365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQ674_RS16375	COG2921	Belongs to the UPF0250 family
GQ674_RS16385	COG1686	Belongs to the peptidase S11 family
GQ674_RS16395	COG2951	lytic endotransglycosylase activity
GQ674_RS16400	COG0772	Belongs to the SEDS family
GQ674_RS16405	COG0772	Belongs to the SEDS family
GQ674_RS16410	COG0768	penicillin binding
GQ674_RS16420	COG1792	Involved in formation and maintenance of cell shape
GQ674_RS16425	COG1077	Cell shape determining protein MreB Mrl
GQ674_RS16435	COG1368	sulfuric ester hydrolase activity
GQ674_RS16450	COG0308	aminopeptidase N
GQ674_RS16455	COG5001	Diguanylate cyclase
GQ674_RS16460	COG2226	methyltransferase
GQ674_RS16485	COG1538	Outer membrane efflux protein
GQ674_RS16490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS16495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS16500	COG1309	transcriptional regulator
GQ674_RS16510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GQ674_RS16525	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQ674_RS16535	COG2832	Protein of unknown function (DUF454)
GQ674_RS16550	COG1505	serine-type exopeptidase activity
GQ674_RS16565	COG2011	ABC-type metal ion transport system permease component
GQ674_RS16575	COG0697	spore germination
GQ674_RS16620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQ674_RS16645	COG1573	uracil-dna glycosylase
GQ674_RS16655	COG0517	IMP dehydrogenase activity
GQ674_RS16660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQ674_RS16670	COG1136	(ABC) transporter
GQ674_RS16680	COG0577	efflux transmembrane transporter activity
GQ674_RS16680	COG1136	(ABC) transporter
GQ674_RS16695	COG4191	Histidine kinase
GQ674_RS16700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQ674_RS16715	COG1605	Chorismate mutase
GQ674_RS16715	COG0287	Prephenate dehydrogenase
GQ674_RS16720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQ674_RS16725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQ674_RS16735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQ674_RS16740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQ674_RS16745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQ674_RS16755	COG0356	it plays a direct role in the translocation of protons across the membrane
GQ674_RS16770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQ674_RS16780	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQ674_RS16800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GQ674_RS16825	COG0181	hydroxymethylbilane synthase activity
GQ674_RS16835	COG3275	phosphorelay sensor kinase activity
GQ674_RS16850	COG4771	TonB-dependent receptor
GQ674_RS16870	COG0840	transmembrane signaling receptor activity
GQ674_RS16875	COG0659	secondary active sulfate transmembrane transporter activity
GQ674_RS16885	COG0697	spore germination
GQ674_RS16890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQ674_RS16895	COG5001	Diguanylate cyclase
GQ674_RS16895	COG3300	MHYT domain
GQ674_RS16920	COG3550	peptidyl-serine autophosphorylation
GQ674_RS16930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQ674_RS16935	COG1490	D-aminoacyl-tRNA deacylase activity
GQ674_RS16945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQ674_RS16985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQ674_RS16985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQ674_RS16990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQ674_RS16995	COG0242	peptide deformylase activity
GQ674_RS17005	COG0758	DNA mediated transformation
GQ674_RS17010	COG2922	Belongs to the Smg family
GQ674_RS17020	COG1714	RDD family
GQ674_RS17030	COG0009	L-threonylcarbamoyladenylate synthase
GQ674_RS17055	COG0616	signal peptide processing
GQ674_RS17060	COG0534	Mate efflux family protein
GQ674_RS17075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQ674_RS17080	COG0625	glutathione transferase activity
GQ674_RS17095	COG1252	NADH dehydrogenase
GQ674_RS17130	COG2860	membrane
GQ674_RS17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS17140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS17155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQ674_RS17175	COG2801	Transposase and inactivated derivatives
GQ674_RS17180	COG2842	Transposition protein
GQ674_RS17200	COG5566	PFAM Mor transcription activator
GQ674_RS17280	COG1846	Transcriptional regulator
GQ674_RS17285	COG2205	protein histidine kinase activity
GQ674_RS17290	COG0745	RESPONSE REGULATOR receiver
GQ674_RS17300	COG0459	protein refolding
GQ674_RS17305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQ674_RS17310	COG2356	endonuclease I
GQ674_RS17315	COG1324	tolerance protein
GQ674_RS17320	COG4232	protein-disulfide reductase activity
GQ674_RS17325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQ674_RS17345	COG0840	transmembrane signaling receptor activity
GQ674_RS17360	COG4977	sequence-specific DNA binding
GQ674_RS17370	COG0739	heme binding
GQ674_RS17390	COG4251	negative regulation of phosphorylation
GQ674_RS17395	COG0784	Response regulator, receiver
GQ674_RS17425	COG4585	Histidine kinase
GQ674_RS17435	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GQ674_RS17440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQ674_RS17440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQ674_RS17465	COG1309	transcriptional regulator
GQ674_RS17470	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS17535	COG0431	NADPH-dependent FMN reductase
GQ674_RS17545	COG0798	PFAM Bile acid sodium symporter
GQ674_RS17580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQ674_RS17590	COG0511	ligase activity, forming carbon-carbon bonds
GQ674_RS17595	COG0439	Biotin carboxylase
GQ674_RS17620	COG2264	protein methyltransferase activity
GQ674_RS17630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GQ674_RS17635	COG4589	Belongs to the CDS family
GQ674_RS17650	COG0671	phosphoesterase, PA-phosphatase related
GQ674_RS17650	COG2453	phosphatase
GQ674_RS17655	COG2267	carboxylic ester hydrolase activity
GQ674_RS17660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQ674_RS17670	COG0138	bifunctional purine biosynthesis protein purh
GQ674_RS17685	COG0151	Belongs to the GarS family
GQ674_RS17710	COG2932	Transcriptional regulator
GQ674_RS17715	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQ674_RS17720	COG2201	protein-glutamate methylesterase activity
GQ674_RS17725	COG2177	Part of the ABC transporter FtsEX involved in
GQ674_RS17730	COG2884	Cell division ATP-binding protein ftsE
GQ674_RS17735	COG0513	Belongs to the DEAD box helicase family
GQ674_RS17740	COG3118	belongs to the thioredoxin family
GQ674_RS17745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GQ674_RS17755	COG1609	Transcriptional regulator
GQ674_RS17775	COG3706	GGDEF domain
GQ674_RS17785	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GQ674_RS17835	COG1652	LysM domain
GQ674_RS17840	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GQ674_RS17840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GQ674_RS17850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS17855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQ674_RS17870	COG1289	transmembrane transporter activity
GQ674_RS17910	COG0316	Belongs to the HesB IscA family
GQ674_RS17950	COG1051	belongs to the nudix hydrolase family
GQ674_RS17965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQ674_RS17970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQ674_RS17975	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GQ674_RS17980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GQ674_RS17985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQ674_RS17990	COG0730	response to heat
GQ674_RS18000	COG0134	indole-3-glycerol-phosphate synthase activity
GQ674_RS18005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQ674_RS18025	COG1597	lipid kinase activity
GQ674_RS18040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GQ674_RS18045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQ674_RS18055	COG2111	Na H antiporter
GQ674_RS18055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQ674_RS18060	COG1006	Multisubunit Na H antiporter MnhC subunit
GQ674_RS18065	COG0651	ATP synthesis coupled electron transport
GQ674_RS18070	COG1863	multisubunit Na H antiporter MnhE subunit
GQ674_RS18075	COG2212	antiporter activity
GQ674_RS18080	COG1320	monovalent cation:proton antiporter activity
GQ674_RS18085	COG0530	calcium, potassium:sodium antiporter activity
GQ674_RS18135	COG3104	oligopeptide transport
GQ674_RS18140	COG3483	tryptophan 2,3-dioxygenase activity
GQ674_RS18145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQ674_RS18170	COG0745	RESPONSE REGULATOR receiver
GQ674_RS18170	COG3706	GGDEF domain
GQ674_RS18185	COG2354	Protein conserved in bacteria
GQ674_RS18190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQ674_RS18195	COG1368	sulfuric ester hydrolase activity
GQ674_RS18200	COG1196	nuclear chromosome segregation
GQ674_RS18200	COG3264	Mechanosensitive ion channel
GQ674_RS18215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQ674_RS18215	COG0723	plastoquinol--plastocyanin reductase activity
GQ674_RS18235	COG0745	RESPONSE REGULATOR receiver
GQ674_RS18250	COG1166	arginine decarboxylase activity
GQ674_RS18255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQ674_RS18275	COG2960	long-chain fatty acid transporting porin activity
GQ674_RS18280	COG0561	phosphatase activity
GQ674_RS18305	COG3550	peptidyl-serine autophosphorylation
GQ674_RS18325	COG0583	DNA-binding transcription factor activity
GQ674_RS18390	COG2031	fatty acid transporter
GQ674_RS18395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQ674_RS18430	COG0811	peptide transport
GQ674_RS18435	COG2831	hemolysin activation secretion protein
GQ674_RS18470	COG0673	inositol 2-dehydrogenase activity
GQ674_RS18485	COG2222	sugar isomerase
GQ674_RS18490	COG1940	carbohydrate kinase activity
GQ674_RS18500	COG1349	DNA-binding transcription factor activity
GQ674_RS18505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQ674_RS18510	COG2814	Major facilitator Superfamily
GQ674_RS18530	COG1040	competence protein
GQ674_RS18540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQ674_RS18550	COG2267	carboxylic ester hydrolase activity
GQ674_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS18585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GQ674_RS18610	COG0714	Associated with various cellular activities
GQ674_RS18625	COG0754	glutathionylspermidine amidase activity
GQ674_RS18630	COG5463	Belongs to the UPF0441 family
GQ674_RS18635	COG0129	dihydroxy-acid dehydratase activity
GQ674_RS18650	COG1199	ATP-dependent helicase activity
GQ674_RS18660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQ674_RS18680	COG3781	membrane
GQ674_RS18710	COG0625	glutathione transferase activity
GQ674_RS18755	COG4555	ABC transporter
GQ674_RS18775	COG1131	(ABC) transporter
GQ674_RS18780	COG0842	Transport permease protein
GQ674_RS18785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQ674_RS18795	COG0084	hydrolase, TatD family'
GQ674_RS18805	COG1643	Atp-dependent helicase
GQ674_RS18815	COG1187	pseudouridine synthase activity
GQ674_RS18825	COG0667	Aldo Keto reductase
GQ674_RS18830	COG1690	Belongs to the RtcB family
GQ674_RS18835	COG3634	alkyl hydroperoxide reductase activity
GQ674_RS18840	COG1959	2 iron, 2 sulfur cluster binding
GQ674_RS18845	COG0840	transmembrane signaling receptor activity
GQ674_RS18850	COG0583	DNA-binding transcription factor activity
GQ674_RS18855	COG2814	Major facilitator Superfamily
GQ674_RS18860	COG0656	L-ascorbic acid biosynthetic process
GQ674_RS18865	COG2267	carboxylic ester hydrolase activity
GQ674_RS18870	COG1042	CoA-binding domain protein
GQ674_RS18870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQ674_RS18870	COG0045	succinate-CoA ligase (ADP-forming) activity
GQ674_RS18875	COG2239	Acts as a magnesium transporter
GQ674_RS18890	COG3100	YcgL domain-containing protein
GQ674_RS18905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQ674_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS18920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQ674_RS18950	COG2986	histidine ammonia-lyase
GQ674_RS18960	COG1216	Glycosyl transferase, family 2
GQ674_RS18975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQ674_RS18980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQ674_RS18995	COG0251	oxidation-reduction process
GQ674_RS19000	COG1294	oxidase, subunit
GQ674_RS19005	COG1271	oxidase subunit
GQ674_RS19015	COG0494	nUDIX hydrolase
GQ674_RS19035	COG0408	coproporphyrinogen oxidase activity
GQ674_RS19040	COG2323	membrane
GQ674_RS19060	COG0589	response to stress
GQ674_RS19080	COG0430	RNA-3'-phosphate cyclase activity
GQ674_RS19085	COG1690	Belongs to the RtcB family
GQ674_RS19090	COG4650	regulator
GQ674_RS19100	COG0210	DNA helicase
GQ674_RS19115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQ674_RS19120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQ674_RS19125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQ674_RS19170	COG0463	Glycosyl transferase, family 2
GQ674_RS19190	COG1475	DNA binding
GQ674_RS19195	COG1192	Involved in chromosome partitioning
GQ674_RS19200	COG0357	Ribosomal RNA small subunit methyltransferase G
GQ674_RS19230	COG0477	Major facilitator Superfamily
GQ674_RS19255	COG1971	Probably functions as a manganese efflux pump
GQ674_RS19270	COG0443	Heat shock 70 kDa protein
GQ674_RS19280	COG2911	Protein conserved in bacteria
GQ674_RS19285	COG0729	surface antigen
GQ674_RS19295	COG0752	glycyl-tRNA synthetase alpha subunit
GQ674_RS19305	COG0519	Catalyzes the synthesis of GMP from XMP
GQ674_RS19305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQ674_RS19315	COG0805	protein transport
GQ674_RS19325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQ674_RS19335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQ674_RS19350	COG0840	transmembrane signaling receptor activity
GQ674_RS19405	COG3135	benzoate transporter
GQ674_RS19415	COG0676	glucose-6-phosphate 1-epimerase activity
GQ674_RS19420	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GQ674_RS19425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQ674_RS19430	COG0745	RESPONSE REGULATOR receiver
GQ674_RS19430	COG3706	GGDEF domain
GQ674_RS19435	COG3012	SEC-C Motif Domain Protein
GQ674_RS19460	COG0302	gtp cyclohydrolase
GQ674_RS19485	COG1289	transmembrane transporter activity
GQ674_RS19495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQ674_RS19500	COG1074	ATP-dependent DNA helicase activity
GQ674_RS19505	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GQ674_RS19510	COG1127	ABC transporter
GQ674_RS19515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQ674_RS19520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GQ674_RS19535	COG2853	Lipoprotein
GQ674_RS19540	COG0386	Belongs to the glutathione peroxidase family
GQ674_RS19550	COG1322	Protein conserved in bacteria
GQ674_RS19565	COG0604	alcohol dehydrogenase
GQ674_RS19570	COG0583	DNA-binding transcription factor activity
GQ674_RS19590	COG0667	Aldo Keto reductase
GQ674_RS19605	COG0531	amino acid
GQ674_RS19615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQ674_RS19620	COG0861	Integral membrane protein TerC family
GQ674_RS19635	COG0584	glycerophosphoryl diester phosphodiesterase
GQ674_RS19650	COG0706	membrane insertase activity
GQ674_RS19655	COG0594	ribonuclease P activity
GQ674_RS19660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GQ674_RS19665	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQ674_RS19675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQ674_RS19680	COG0187	DNA topoisomerase II activity
GQ674_RS19690	COG0501	Belongs to the peptidase M48B family
GQ674_RS19745	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQ674_RS19755	COG4772	TonB-dependent receptor
GQ674_RS19795	COG1012	belongs to the aldehyde dehydrogenase family
GQ674_RS19800	COG3284	Transcriptional regulator
GQ674_RS19805	COG0800	Aldolase
GQ674_RS19830	COG0384	phenazine biosynthesis protein PhzF
GQ674_RS19840	COG2755	lipolytic protein G-D-S-L family
GQ674_RS19845	COG2272	Belongs to the type-B carboxylesterase lipase family
GQ674_RS19850	COG2755	lipolytic protein G-D-S-L family
GQ674_RS19850	COG0657	acetylesterase activity
GQ674_RS19860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GQ674_RS19880	COG3507	Belongs to the glycosyl hydrolase 43 family
GQ674_RS19885	COG1609	Transcriptional regulator
GQ674_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS19900	COG2755	lipolytic protein G-D-S-L family
GQ674_RS19910	COG3186	Phenylalanine-4-hydroxylase
GQ674_RS19915	COG1522	sequence-specific DNA binding
GQ674_RS19920	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQ674_RS19930	COG4771	TonB-dependent receptor
GQ674_RS19950	COG1119	ATPase activity
GQ674_RS19965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQ674_RS19975	COG2815	serine threonine protein kinase
GQ674_RS19975	COG0515	serine threonine protein kinase
GQ674_RS19980	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GQ674_RS19985	COG1435	thymidine kinase activity
GQ674_RS19990	COG0210	DNA helicase
GQ674_RS20000	COG3132	Protein of unknown function, DUF480
GQ674_RS20005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GQ674_RS20010	COG0284	orotidine-5'-phosphate decarboxylase activity
GQ674_RS20025	COG2937	Belongs to the GPAT DAPAT family
GQ674_RS20035	COG0037	tRNA processing
GQ674_RS20040	COG2974	May be involved in recombination
GQ674_RS20060	COG0493	'glutamate synthase
GQ674_RS20065	COG0067	glutamate synthase
GQ674_RS20065	COG0069	glutamate synthase activity
GQ674_RS20065	COG0070	glutamate synthase
GQ674_RS20085	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS20090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQ674_RS20115	COG1205	dead DEAH box helicase
GQ674_RS20115	COG1111	helicase
GQ674_RS20150	COG0714	Associated with various cellular activities
GQ674_RS20195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQ674_RS20215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQ674_RS20250	COG1968	undecaprenyl-diphosphatase activity
GQ674_RS20255	COG0174	glutamine synthetase
GQ674_RS20260	COG0347	Belongs to the P(II) protein family
GQ674_RS20265	COG0004	ammonium transporteR
GQ674_RS20275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GQ674_RS20315	COG3852	Histidine kinase
GQ674_RS20325	COG2032	superoxide dismutase activity
GQ674_RS20330	COG2032	superoxide dismutase activity
GQ674_RS20370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQ674_RS20375	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GQ674_RS20380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQ674_RS20460	COG2200	EAL domain
GQ674_RS20475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS20520	COG2197	response regulator
GQ674_RS20525	COG2205	protein histidine kinase activity
GQ674_RS20525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQ674_RS20540	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS20545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GQ674_RS20555	COG0612	Peptidase, M16
GQ674_RS20565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQ674_RS20570	COG0596	Alpha beta hydrolase
GQ674_RS20580	COG0318	PFAM AMP-dependent synthetase and ligase
GQ674_RS20585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQ674_RS20595	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQ674_RS20605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQ674_RS20615	COG0564	pseudouridine synthase activity
GQ674_RS20635	COG0339	signal peptide processing
GQ674_RS20650	COG0681	Belongs to the peptidase S26 family
GQ674_RS20655	COG2814	Major facilitator Superfamily
GQ674_RS20665	COG0583	DNA-binding transcription factor activity
GQ674_RS20670	COG0583	DNA-binding transcription factor activity
GQ674_RS20675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GQ674_RS20680	COG2224	Isocitrate lyase
GQ674_RS20685	COG3706	GGDEF domain
GQ674_RS20710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQ674_RS20715	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS20735	COG0697	spore germination
GQ674_RS20745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GQ674_RS20760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQ674_RS20765	COG1607	acyl-coa hydrolase
GQ674_RS20775	COG1902	pentaerythritol trinitrate reductase activity
GQ674_RS20780	COG0583	DNA-binding transcription factor activity
GQ674_RS20785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQ674_RS20795	COG1335	isochorismatase
GQ674_RS20800	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQ674_RS20815	COG1056	cytidyltransferase-related domain
GQ674_RS20815	COG1051	belongs to the nudix hydrolase family
GQ674_RS20825	COG3201	nicotinamide mononucleotide transporter
GQ674_RS20850	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GQ674_RS20860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQ674_RS20885	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQ674_RS20890	COG1396	sequence-specific DNA binding
GQ674_RS20890	COG3800	Transcriptional regulator
GQ674_RS20900	COG1960	acyl-CoA dehydrogenase activity
GQ674_RS20905	COG1024	Enoyl-CoA hydratase
GQ674_RS20910	COG1024	Enoyl-CoA hydratase
GQ674_RS20920	COG1764	response to oxidative stress
GQ674_RS20985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQ674_RS20995	COG0745	RESPONSE REGULATOR receiver
GQ674_RS21000	COG2205	protein histidine kinase activity
GQ674_RS21005	COG3228	Belongs to the MtfA family
GQ674_RS21015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GQ674_RS21015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GQ674_RS21020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GQ674_RS21070	COG3237	CsbD-like
GQ674_RS21080	COG0180	Tryptophanyl-tRNA synthetase
GQ674_RS21105	COG0477	Major facilitator Superfamily
GQ674_RS21110	COG0697	spore germination
GQ674_RS21115	COG2962	Rard protein
GQ674_RS21130	COG1136	(ABC) transporter
GQ674_RS21130	COG0577	efflux transmembrane transporter activity
GQ674_RS21135	COG1136	(ABC) transporter
GQ674_RS21140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQ674_RS21145	COG1131	(ABC) transporter
GQ674_RS21155	COG4585	Histidine kinase
GQ674_RS21160	COG2197	response regulator
GQ674_RS21175	COG0753	catalase activity
GQ674_RS21180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQ674_RS21185	COG1011	Hydrolase
GQ674_RS21190	COG0628	permease
GQ674_RS21210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQ674_RS21220	COG3501	Rhs element vgr protein
GQ674_RS21230	COG3209	COG3209 Rhs family protein
GQ674_RS21245	COG3209	COG3209 Rhs family protein
GQ674_RS21290	COG5507	3-demethylubiquinone-9 3-methyltransferase
GQ674_RS21320	COG2816	NAD+ diphosphatase activity
GQ674_RS21335	COG1028	Short-chain dehydrogenase reductase Sdr
GQ674_RS21340	COG2271	Major facilitator Superfamily
GQ674_RS21360	COG2186	Transcriptional regulator
GQ674_RS21375	COG2814	Major facilitator Superfamily
GQ674_RS21380	COG0583	DNA-binding transcription factor activity
GQ674_RS21385	COG4807	Protein conserved in bacteria
GQ674_RS21395	COG4221	oxidoreductase activity
GQ674_RS21415	COG0018	arginyl-trna synthetase
GQ674_RS21420	COG2003	Belongs to the UPF0758 family
GQ674_RS21425	COG3177	Filamentation induced by cAMP protein fic
GQ674_RS21430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GQ674_RS21435	COG0756	dUTP diphosphatase activity
GQ674_RS21450	COG2205	protein histidine kinase activity
GQ674_RS21460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system