locus-tag	class	description
MG068_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MG068_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MG068_RS00020	COG0187	DNA topoisomerase II activity
MG068_RS00030	COG0501	Belongs to the peptidase M48B family
MG068_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG068_RS00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MG068_RS00095	COG4772	TonB-dependent receptor
MG068_RS00130	COG0800	Aldolase
MG068_RS00145	COG3186	Phenylalanine-4-hydroxylase
MG068_RS00150	COG1522	sequence-specific DNA binding
MG068_RS00160	COG1752	Esterase of the alpha-beta hydrolase superfamily
MG068_RS00190	COG1122	ATPase activity
MG068_RS00205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MG068_RS00210	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MG068_RS00225	COG0210	DNA helicase
MG068_RS00235	COG3132	Protein of unknown function, DUF480
MG068_RS00240	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MG068_RS00245	COG0284	orotidine-5'-phosphate decarboxylase activity
MG068_RS00255	COG2937	Belongs to the GPAT DAPAT family
MG068_RS00265	COG0037	tRNA processing
MG068_RS00270	COG2974	May be involved in recombination
MG068_RS00285	COG1803	Methylglyoxal synthase
MG068_RS00290	COG2205	protein histidine kinase activity
MG068_RS00290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG068_RS00295	COG0493	'glutamate synthase
MG068_RS00300	COG0067	glutamate synthase
MG068_RS00300	COG0069	glutamate synthase activity
MG068_RS00300	COG0070	glutamate synthase
MG068_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS00325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG068_RS00350	COG1205	dead DEAH box helicase
MG068_RS00350	COG1111	helicase
MG068_RS00385	COG0714	Associated with various cellular activities
MG068_RS00405	COG0312	modulator of DNA gyrase
MG068_RS00420	COG3550	peptidyl-serine autophosphorylation
MG068_RS00440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MG068_RS00460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG068_RS00495	COG1968	undecaprenyl-diphosphatase activity
MG068_RS00500	COG0174	glutamine synthetase
MG068_RS00510	COG0347	Belongs to the P(II) protein family
MG068_RS00515	COG0004	ammonium transporteR
MG068_RS00525	COG3279	Response regulator of the LytR AlgR family
MG068_RS00540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MG068_RS00560	COG3852	Histidine kinase
MG068_RS00565	COG2204	response regulator
MG068_RS00570	COG2032	superoxide dismutase activity
MG068_RS00575	COG2032	superoxide dismutase activity
MG068_RS00585	COG0183	Belongs to the thiolase family
MG068_RS00620	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MG068_RS00625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MG068_RS00680	COG2837	iron assimilation
MG068_RS00720	COG2197	response regulator
MG068_RS00725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG068_RS00725	COG2205	protein histidine kinase activity
MG068_RS00730	COG3474	cytochrome
MG068_RS00740	COG1960	acyl-CoA dehydrogenase activity
MG068_RS00745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MG068_RS00755	COG0612	Peptidase, M16
MG068_RS00765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MG068_RS00770	COG0596	Alpha beta hydrolase
MG068_RS00780	COG0318	PFAM AMP-dependent synthetase and ligase
MG068_RS00785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG068_RS00795	COG1181	Belongs to the D-alanine--D-alanine ligase family
MG068_RS00810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MG068_RS00840	COG0339	signal peptide processing
MG068_RS00860	COG0681	Belongs to the peptidase S26 family
MG068_RS00865	COG2814	Major facilitator Superfamily
MG068_RS00870	COG0583	DNA-binding transcription factor activity
MG068_RS00875	COG0583	DNA-binding transcription factor activity
MG068_RS00880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MG068_RS00885	COG2224	Isocitrate lyase
MG068_RS00890	COG3706	GGDEF domain
MG068_RS00915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MG068_RS00920	COG1960	acyl-CoA dehydrogenase activity
MG068_RS00940	COG0697	spore germination
MG068_RS00950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MG068_RS00965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MG068_RS00970	COG1280	lysine exporter protein (LysE YggA)
MG068_RS00975	COG1607	acyl-coa hydrolase
MG068_RS00985	COG1902	pentaerythritol trinitrate reductase activity
MG068_RS01000	COG1335	isochorismatase
MG068_RS01005	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MG068_RS01010	COG1752	Esterase of the alpha-beta hydrolase superfamily
MG068_RS01025	COG3800	Transcriptional regulator
MG068_RS01025	COG1396	sequence-specific DNA binding
MG068_RS01035	COG1960	acyl-CoA dehydrogenase activity
MG068_RS01040	COG1024	Enoyl-CoA hydratase
MG068_RS01045	COG1024	Enoyl-CoA hydratase
MG068_RS01065	COG1764	response to oxidative stress
MG068_RS01075	COG0659	secondary active sulfate transmembrane transporter activity
MG068_RS01085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MG068_RS01110	COG3228	Belongs to the MtfA family
MG068_RS01120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MG068_RS01120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MG068_RS01125	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MG068_RS01150	COG3657	addiction module killer protein
MG068_RS01190	COG3237	CsbD-like
MG068_RS01200	COG0180	Tryptophanyl-tRNA synthetase
MG068_RS01225	COG0477	Major facilitator Superfamily
MG068_RS01230	COG0697	spore germination
MG068_RS01240	COG4206	TonB-dependent receptor
MG068_RS01245	COG0577	efflux transmembrane transporter activity
MG068_RS01245	COG1136	(ABC) transporter
MG068_RS01255	COG1136	(ABC) transporter
MG068_RS01260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS01275	COG4585	Histidine kinase
MG068_RS01280	COG2197	response regulator
MG068_RS01290	COG0753	catalase activity
MG068_RS01295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MG068_RS01305	COG0628	permease
MG068_RS01325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG068_RS01340	COG5507	3-demethylubiquinone-9 3-methyltransferase
MG068_RS01345	COG0823	Involved in the tonB-independent uptake of proteins
MG068_RS01345	COG1506	peptidase
MG068_RS01355	COG2197	response regulator
MG068_RS01370	COG2814	Major facilitator Superfamily
MG068_RS01375	COG0583	DNA-binding transcription factor activity
MG068_RS01380	COG4807	Protein conserved in bacteria
MG068_RS01385	COG4221	oxidoreductase activity
MG068_RS01400	COG0018	arginyl-trna synthetase
MG068_RS01405	COG2003	Belongs to the UPF0758 family
MG068_RS01410	COG2197	response regulator
MG068_RS01415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MG068_RS01420	COG0756	dUTP diphosphatase activity
MG068_RS01435	COG2205	protein histidine kinase activity
MG068_RS01445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MG068_RS01450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MG068_RS01465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MG068_RS01470	COG0708	Exodeoxyribonuclease III
MG068_RS01475	COG2223	nitrite transmembrane transporter activity
MG068_RS01490	COG0739	heme binding
MG068_RS01530	COG2234	aminopeptidase activity
MG068_RS01540	COG4942	peptidase
MG068_RS01545	COG0793	Belongs to the peptidase S41A family
MG068_RS01580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MG068_RS01625	COG0109	protoheme IX farnesyltransferase activity
MG068_RS01650	COG0358	DNA primase activity
MG068_RS01655	COG1295	ribonuclease BN
MG068_RS01670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MG068_RS01680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MG068_RS01685	COG0668	transmembrane transport
MG068_RS01700	COG2133	pyrroloquinoline quinone binding
MG068_RS01705	COG4682	membrane
MG068_RS01715	COG0531	amino acid
MG068_RS01725	COG1737	Transcriptional regulator
MG068_RS01730	COG4948	Mandelate Racemase Muconate Lactonizing
MG068_RS01780	COG5383	Protein conserved in bacteria
MG068_RS01790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MG068_RS01795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MG068_RS01825	COG0778	Nitroreductase
MG068_RS01830	COG2353	YceI-like domain
MG068_RS01845	COG2375	cellular response to nickel ion
MG068_RS01880	COG1192	Involved in chromosome partitioning
MG068_RS01985	COG2267	carboxylic ester hydrolase activity
MG068_RS02045	COG0488	(ABC) transporter
MG068_RS02050	COG0583	DNA-binding transcription factor activity
MG068_RS02060	COG2814	Major facilitator Superfamily
MG068_RS02065	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MG068_RS02070	COG1113	amino acid transport
MG068_RS02075	COG0741	lytic transglycosylase activity
MG068_RS02100	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MG068_RS02110	COG5507	3-demethylubiquinone-9 3-methyltransferase
MG068_RS02115	COG4941	Belongs to the sigma-70 factor family
MG068_RS02145	COG3275	phosphorelay sensor kinase activity
MG068_RS02150	COG3279	Response regulator of the LytR AlgR family
MG068_RS02170	COG1309	transcriptional regulator
MG068_RS02180	COG2814	Major facilitator Superfamily
MG068_RS02185	COG3590	peptidase
MG068_RS02190	COG5001	Diguanylate cyclase
MG068_RS02195	COG0583	DNA-binding transcription factor activity
MG068_RS02205	COG3384	dioxygenase
MG068_RS02210	COG0025	NhaP-type Na H and K H
MG068_RS02240	COG1360	Flagellar Motor Protein
MG068_RS02270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG068_RS02285	COG0784	Response regulator, receiver
MG068_RS02285	COG2205	protein histidine kinase activity
MG068_RS02300	COG2813	Specifically methylates the guanine in position
MG068_RS02305	COG1187	pseudouridine synthase activity
MG068_RS02310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MG068_RS02320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MG068_RS02325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MG068_RS02340	COG0583	DNA-binding transcription factor activity
MG068_RS02345	COG2226	methyltransferase
MG068_RS02370	COG1956	GAF domain-containing protein
MG068_RS02375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MG068_RS02385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG068_RS02390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MG068_RS02395	COG0785	Cytochrome C biogenesis protein
MG068_RS02395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG068_RS02400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MG068_RS02405	COG0745	RESPONSE REGULATOR receiver
MG068_RS02410	COG5002	protein histidine kinase activity
MG068_RS02415	COG2205	protein histidine kinase activity
MG068_RS02420	COG0745	RESPONSE REGULATOR receiver
MG068_RS02425	COG0367	asparagine synthase
MG068_RS02435	COG0720	synthase
MG068_RS02455	COG0513	Belongs to the DEAD box helicase family
MG068_RS02465	COG0625	glutathione transferase activity
MG068_RS02470	COG1573	uracil-dna glycosylase
MG068_RS02505	COG0626	cystathionine gamma-synthase activity
MG068_RS02540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MG068_RS02550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MG068_RS02555	COG2076	Multidrug Resistance protein
MG068_RS02565	COG0463	Glycosyl transferase, family 2
MG068_RS02605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MG068_RS02610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MG068_RS02640	COG1127	ABC transporter
MG068_RS02645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MG068_RS02660	COG0442	prolyl-tRNA aminoacylation
MG068_RS02675	COG1183	phosphatidylcholine synthase activity
MG068_RS02685	COG0456	acetyltransferase
MG068_RS02695	COG0525	valine-tRNA ligase activity
MG068_RS02710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MG068_RS02720	COG0795	lipopolysaccharide-transporting ATPase activity
MG068_RS02735	COG4974	Belongs to the 'phage' integrase family
MG068_RS02740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MG068_RS02750	COG0047	phosphoribosylformylglycinamidine synthase activity
MG068_RS02750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MG068_RS02755	COG5295	Hep Hag repeat protein
MG068_RS02760	COG1404	Belongs to the peptidase S8 family
MG068_RS02765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MG068_RS02770	COG1459	type II secretion system
MG068_RS02775	COG2165	general secretion pathway protein
MG068_RS02780	COG4970	Tfp pilus assembly protein FimT
MG068_RS02785	COG2165	general secretion pathway protein
MG068_RS02790	COG4795	General secretion pathway protein
MG068_RS02795	COG3156	type II secretion system protein K
MG068_RS02800	COG3166	PFAM Fimbrial assembly family protein
MG068_RS02815	COG1450	Type ii and iii secretion system protein
MG068_RS02825	COG0463	Glycosyl transferase, family 2
MG068_RS02840	COG3539	Fimbrial protein
MG068_RS02860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MG068_RS02870	COG1215	transferase activity, transferring glycosyl groups
MG068_RS02885	COG2252	PERMEase
MG068_RS02890	COG0488	(ABC) transporter
MG068_RS02900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MG068_RS02915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MG068_RS02920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MG068_RS02920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MG068_RS02950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MG068_RS02955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MG068_RS02970	COG0277	FAD linked oxidase domain protein
MG068_RS02975	COG1988	membrane-bound metal-dependent
MG068_RS03015	COG2001	Belongs to the MraZ family
MG068_RS03020	COG0275	rRNA processing
MG068_RS03025	COG3116	cell division
MG068_RS03035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MG068_RS03040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MG068_RS03060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MG068_RS03065	COG1181	Belongs to the D-alanine--D-alanine ligase family
MG068_RS03070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MG068_RS03080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MG068_RS03085	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MG068_RS03095	COG0739	heme binding
MG068_RS03100	COG0653	protein targeting
MG068_RS03105	COG0494	nUDIX hydrolase
MG068_RS03115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MG068_RS03125	COG3275	phosphorelay sensor kinase activity
MG068_RS03130	COG3279	Response regulator of the LytR AlgR family
MG068_RS03155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MG068_RS03160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MG068_RS03170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MG068_RS03175	COG1607	acyl-coa hydrolase
MG068_RS03180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MG068_RS03205	COG4106	trans-aconitate 2-methyltransferase activity
MG068_RS03210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MG068_RS03220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG068_RS03225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MG068_RS03230	COG0667	Aldo Keto reductase
MG068_RS03245	COG4771	TonB-dependent receptor
MG068_RS03265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MG068_RS03270	COG4181	ATPase activity
MG068_RS03285	COG0642	Histidine kinase
MG068_RS03295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MG068_RS03300	COG0861	Integral membrane protein TerC family
MG068_RS03305	COG2814	Major facilitator Superfamily
MG068_RS03310	COG1704	LemA family
MG068_RS03325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MG068_RS03330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MG068_RS03345	COG3738	Protein conserved in bacteria
MG068_RS03350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MG068_RS03355	COG2967	ApaG domain
MG068_RS03360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MG068_RS03365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MG068_RS03370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MG068_RS03375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MG068_RS03385	COG2096	Adenosyltransferase
MG068_RS03395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG068_RS03400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG068_RS03405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MG068_RS03410	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MG068_RS03430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MG068_RS03440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MG068_RS03450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MG068_RS03455	COG0583	DNA-binding transcription factor activity
MG068_RS03460	COG3634	alkyl hydroperoxide reductase activity
MG068_RS03480	COG0583	DNA-binding transcription factor activity
MG068_RS03520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MG068_RS03545	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MG068_RS03560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MG068_RS03580	COG1404	Belongs to the peptidase S8 family
MG068_RS03600	COG1295	ribonuclease BN
MG068_RS03605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG068_RS03620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MG068_RS03625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MG068_RS03640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MG068_RS03650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MG068_RS03655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MG068_RS03660	COG0193	aminoacyl-tRNA hydrolase activity
MG068_RS03665	COG0012	GTP binding
MG068_RS03670	COG4206	TonB-dependent receptor
MG068_RS03675	COG4242	Belongs to the peptidase S51 family
MG068_RS03700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MG068_RS03715	COG0250	Participates in transcription elongation, termination and antitermination
MG068_RS03720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MG068_RS03725	COG0081	regulation of translation
MG068_RS03735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MG068_RS03740	COG0222	ribosome binding
MG068_RS03745	COG0085	RNA polymerase activity
MG068_RS03750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MG068_RS03755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MG068_RS03760	COG0049	tRNA binding
MG068_RS03765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MG068_RS03770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MG068_RS03775	COG0051	transcription antitermination factor activity, RNA binding
MG068_RS03780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MG068_RS03785	COG0088	Forms part of the polypeptide exit tunnel
MG068_RS03790	COG0089	rRNA binding
MG068_RS03795	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MG068_RS03800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MG068_RS03805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MG068_RS03810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MG068_RS03815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MG068_RS03820	COG0255	Belongs to the universal ribosomal protein uL29 family
MG068_RS03825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MG068_RS03830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MG068_RS03835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MG068_RS03840	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MG068_RS03845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MG068_RS03855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MG068_RS03860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MG068_RS03865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MG068_RS03870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MG068_RS03875	COG1841	ribosomal large subunit assembly
MG068_RS03880	COG0200	Binds to the 23S rRNA
MG068_RS03885	COG0201	protein transport
MG068_RS03890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MG068_RS03895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MG068_RS03900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MG068_RS03905	COG0202	RNA polymerase activity
MG068_RS03910	COG0203	ribosomal protein L17
MG068_RS03925	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MG068_RS03935	COG0154	amidase activity
MG068_RS03950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MG068_RS03955	COG0039	L-malate dehydrogenase activity
MG068_RS03960	COG0564	pseudouridine synthase activity
MG068_RS03970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MG068_RS03985	COG0625	glutathione transferase activity
MG068_RS03995	COG1902	pentaerythritol trinitrate reductase activity
MG068_RS03995	COG0446	pyridine nucleotide-disulphide oxidoreductase
MG068_RS04000	COG2364	Membrane
MG068_RS04005	COG0604	alcohol dehydrogenase
MG068_RS04020	COG1187	pseudouridine synthase activity
MG068_RS04040	COG1063	alcohol dehydrogenase
MG068_RS04055	COG0588	phosphoglycerate mutase activity
MG068_RS04060	COG0285	dihydrofolate synthase activity
MG068_RS04080	COG2833	Protein of unknown function (DUF455)
MG068_RS04090	COG3291	Pkd domain containing protein
MG068_RS04095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MG068_RS04105	COG0438	transferase activity, transferring glycosyl groups
MG068_RS04120	COG0248	Ppx GppA phosphatase
MG068_RS04130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MG068_RS04145	COG4783	chaperone-mediated protein folding
MG068_RS04160	COG0473	3-isopropylmalate dehydrogenase activity
MG068_RS04235	COG0544	peptidyl-prolyl cis-trans isomerase activity
MG068_RS04240	COG0740	serine-type endopeptidase activity
MG068_RS04245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MG068_RS04285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MG068_RS04290	COG1388	LysM domain
MG068_RS04290	COG3942	CHAP domain
MG068_RS04295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG068_RS04305	COG0328	RNA-DNA hybrid ribonuclease activity
MG068_RS04310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MG068_RS04315	COG0631	protein serine/threonine phosphatase activity
MG068_RS04335	COG0859	PFAM glycosyl transferase family 9
MG068_RS04340	COG3642	lipopolysaccharide core region biosynthetic process
MG068_RS04345	COG1234	tRNA 3'-trailer cleavage
MG068_RS04360	COG2076	Multidrug Resistance protein
MG068_RS04385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MG068_RS04390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MG068_RS04400	COG0537	adenosine 5'-monophosphoramidase activity
MG068_RS04420	COG0714	Associated with various cellular activities
MG068_RS04435	COG1399	metal-binding, possibly nucleic acid-binding protein
MG068_RS04440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MG068_RS04445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MG068_RS04455	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MG068_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS04470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MG068_RS04475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MG068_RS04480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MG068_RS04485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MG068_RS04520	COG4774	siderophore transport
MG068_RS04530	COG2223	nitrite transmembrane transporter activity
MG068_RS04555	COG0583	DNA-binding transcription factor activity
MG068_RS04560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG068_RS04565	COG0697	spore germination
MG068_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS04575	COG0583	DNA-binding transcription factor activity
MG068_RS04580	COG0583	DNA-binding transcription factor activity
MG068_RS04585	COG0477	Major facilitator Superfamily
MG068_RS04595	COG2205	protein histidine kinase activity
MG068_RS04645	COG0583	DNA-binding transcription factor activity
MG068_RS04670	COG0667	Aldo Keto reductase
MG068_RS04685	COG0456	acetyltransferase
MG068_RS04695	COG2818	Glycosylase
MG068_RS04700	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MG068_RS04705	COG1678	Uncharacterized ACR, COG1678
MG068_RS04710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MG068_RS04715	COG0540	Belongs to the ATCase OTCase family
MG068_RS04735	COG2239	Acts as a magnesium transporter
MG068_RS04740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MG068_RS04760	COG1660	Displays ATPase and GTPase activities
MG068_RS04765	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MG068_RS04770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG068_RS04775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MG068_RS04785	COG1137	ATPase activity
MG068_RS04800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MG068_RS04815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MG068_RS04835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MG068_RS04855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MG068_RS04865	COG0628	permease
MG068_RS04875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MG068_RS04885	COG2261	transglycosylase associated protein
MG068_RS04895	COG1555	photosystem II stabilization
MG068_RS04915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MG068_RS04920	COG1477	protein flavinylation
MG068_RS04940	COG4771	TonB-dependent receptor
MG068_RS04950	COG3128	pkhd-type hydroxylase
MG068_RS04995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MG068_RS05000	COG0719	Fe-S assembly protein
MG068_RS05005	COG0396	ATPase activity
MG068_RS05010	COG0719	Fe-S assembly protein
MG068_RS05015	COG1959	2 iron, 2 sulfur cluster binding
MG068_RS05045	COG1764	response to oxidative stress
MG068_RS05050	COG0384	phenazine biosynthesis protein PhzF
MG068_RS05055	COG0384	phenazine biosynthesis protein PhzF
MG068_RS05060	COG0527	aspartate kinase activity
MG068_RS05070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MG068_RS05085	COG0142	geranyltranstransferase activity
MG068_RS05090	COG0366	Alpha amylase catalytic
MG068_RS05100	COG1082	Xylose isomerase domain protein TIM barrel
MG068_RS05110	COG2190	(PTS) system
MG068_RS05110	COG2211	Major facilitator Superfamily
MG068_RS05140	COG1131	(ABC) transporter
MG068_RS05175	COG0629	single-stranded DNA binding
MG068_RS05200	COG2010	Cytochrome c
MG068_RS05210	COG0673	inositol 2-dehydrogenase activity
MG068_RS05215	COG2211	Major facilitator Superfamily
MG068_RS05225	COG1609	Transcriptional regulator
MG068_RS05235	COG0583	DNA-binding transcription factor activity
MG068_RS05275	COG3655	Transcriptional regulator
MG068_RS05280	COG1253	flavin adenine dinucleotide binding
MG068_RS05285	COG1408	metallophosphoesterase
MG068_RS05295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MG068_RS05315	COG2259	Doxx family
MG068_RS05345	COG0477	Major facilitator Superfamily
MG068_RS05360	COG1802	Transcriptional regulator
MG068_RS05395	COG3052	prosthetic group binding
MG068_RS05410	COG0579	oxidoreductase
MG068_RS05435	COG3104	oligopeptide transport
MG068_RS05445	COG1297	OPT oligopeptide transporter protein
MG068_RS05450	COG0823	Involved in the tonB-independent uptake of proteins
MG068_RS05450	COG1506	peptidase
MG068_RS05470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MG068_RS05475	COG2894	cell division
MG068_RS05490	COG4585	Histidine kinase
MG068_RS05495	COG2197	response regulator
MG068_RS05540	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MG068_RS05550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MG068_RS05560	COG1595	DNA-templated transcription, initiation
MG068_RS05570	COG1946	Acyl-CoA thioesterase
MG068_RS05590	COG0824	Thioesterase
MG068_RS05595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MG068_RS05600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MG068_RS05605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MG068_RS05610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MG068_RS05615	COG0268	Binds directly to 16S ribosomal RNA
MG068_RS05620	COG0728	peptidoglycan biosynthetic process
MG068_RS05625	COG0196	riboflavin kinase activity
MG068_RS05630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MG068_RS05640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MG068_RS05665	COG4206	TonB-dependent receptor
MG068_RS05685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MG068_RS05715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MG068_RS05720	COG1845	cytochrome c oxidase, subunit III
MG068_RS05725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MG068_RS05740	COG0326	Molecular chaperone. Has ATPase activity
MG068_RS05760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MG068_RS05780	COG0228	four-way junction DNA binding
MG068_RS05785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MG068_RS05790	COG0336	Belongs to the RNA methyltransferase TrmD family
MG068_RS05795	COG0335	large ribosomal subunit rRNA binding
MG068_RS05815	COG0534	Mate efflux family protein
MG068_RS05840	COG0753	catalase activity
MG068_RS05845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MG068_RS05865	COG0840	transmembrane signaling receptor activity
MG068_RS05885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS05910	COG0024	Methionine aminopeptidase
MG068_RS05935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MG068_RS05960	COG1647	Serine aminopeptidase, S33
MG068_RS05985	COG2814	Major facilitator Superfamily
MG068_RS05990	COG3706	GGDEF domain
MG068_RS06010	COG0588	phosphoglycerate mutase activity
MG068_RS06015	COG3590	peptidase
MG068_RS06025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MG068_RS06035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MG068_RS06040	COG0745	RESPONSE REGULATOR receiver
MG068_RS06045	COG2205	protein histidine kinase activity
MG068_RS06050	COG4452	Inner membrane protein CreD
MG068_RS06065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MG068_RS06070	COG0735	belongs to the Fur family
MG068_RS06115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MG068_RS06155	COG5001	Diguanylate cyclase
MG068_RS06155	COG5002	protein histidine kinase activity
MG068_RS06165	COG1187	pseudouridine synthase activity
MG068_RS06175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MG068_RS06200	COG1132	(ABC) transporter
MG068_RS06250	COG1695	Transcriptional regulator
MG068_RS06270	COG1981	membrane
MG068_RS06275	COG0825	malonyl-CoA metabolic process
MG068_RS06300	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MG068_RS06310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MG068_RS06315	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG068_RS06320	COG0750	zinc metalloprotease
MG068_RS06325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MG068_RS06330	COG0575	Belongs to the CDS family
MG068_RS06335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MG068_RS06340	COG0233	cytoplasmic translational termination
MG068_RS06345	COG0528	UMP kinase activity
MG068_RS06355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MG068_RS06360	COG0052	Belongs to the universal ribosomal protein uS2 family
MG068_RS06380	COG3188	usher protein
MG068_RS06400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MG068_RS06415	COG1393	Belongs to the ArsC family
MG068_RS06420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG068_RS06430	COG0367	asparagine synthase
MG068_RS06435	COG0475	glutathione-regulated potassium exporter activity
MG068_RS06470	COG1566	PFAM secretion protein HlyD family protein
MG068_RS06475	COG2814	Major facilitator Superfamily
MG068_RS06490	COG0583	DNA-binding transcription factor activity
MG068_RS06510	COG1396	sequence-specific DNA binding
MG068_RS06520	COG0662	Cupin 2, conserved barrel domain protein
MG068_RS06530	COG0557	exoribonuclease II activity
MG068_RS06540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MG068_RS06545	COG1538	Outer membrane efflux protein
MG068_RS06550	COG0577	efflux transmembrane transporter activity
MG068_RS06550	COG1136	(ABC) transporter
MG068_RS06555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS06565	COG2205	protein histidine kinase activity
MG068_RS06575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MG068_RS06580	COG2259	Doxx family
MG068_RS06590	COG3220	belongs to the UPF0276 family
MG068_RS06600	COG0704	Plays a role in the regulation of phosphate uptake
MG068_RS06610	COG0581	inorganic phosphate transmembrane transporter activity
MG068_RS06615	COG0573	inorganic phosphate transmembrane transporter activity
MG068_RS06620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MG068_RS06625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MG068_RS06635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MG068_RS06645	COG1024	Enoyl-CoA hydratase
MG068_RS06655	COG0494	nUDIX hydrolase
MG068_RS06675	COG0116	Belongs to the methyltransferase superfamily
MG068_RS06675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MG068_RS06700	COG2733	membrane
MG068_RS06710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MG068_RS06715	COG1012	belongs to the aldehyde dehydrogenase family
MG068_RS06725	COG0477	Major facilitator Superfamily
MG068_RS06730	COG2703	oxygen carrier activity
MG068_RS06755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG068_RS06765	COG0174	glutamine synthetase
MG068_RS06775	COG2072	flavoprotein involved in K transport
MG068_RS06795	COG3842	ATPase activity
MG068_RS06800	COG1176	ABC-type spermidine putrescine transport system, permease component I
MG068_RS06805	COG1177	transmembrane transport
MG068_RS06810	COG1012	belongs to the aldehyde dehydrogenase family
MG068_RS06825	COG4535	Mg2 and Co2 transporter CorC
MG068_RS06845	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MG068_RS06850	COG1702	phosphate starvation-inducible protein PhoH
MG068_RS06855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS06860	COG1131	(ABC) transporter
MG068_RS06865	COG0842	Transport permease protein
MG068_RS06870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MG068_RS06885	COG0741	lytic transglycosylase activity
MG068_RS06890	COG0723	plastoquinol--plastocyanin reductase activity
MG068_RS06895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MG068_RS06900	COG2857	Cytochrome c1
MG068_RS06905	COG0625	glutathione transferase activity
MG068_RS06910	COG2969	positive regulation of protein catabolic process
MG068_RS06945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MG068_RS06955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MG068_RS06970	COG1611	Belongs to the LOG family
MG068_RS07015	COG0556	nucleotide-excision repair
MG068_RS07040	COG3713	MltA-interacting MipA family protein
MG068_RS07055	COG0658	competence protein
MG068_RS07055	COG2333	competence protein COMEC
MG068_RS07060	COG0811	peptide transport
MG068_RS07065	COG0848	biopolymer transport protein
MG068_RS07075	COG1663	tetraacyldisaccharide 4'-kinase activity
MG068_RS07080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MG068_RS07085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MG068_RS07095	COG0322	excinuclease ABC activity
MG068_RS07160	COG0577	efflux transmembrane transporter activity
MG068_RS07160	COG1136	(ABC) transporter
MG068_RS07205	COG0456	acetyltransferase
MG068_RS07205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG068_RS07210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MG068_RS07235	COG0187	DNA topoisomerase II activity
MG068_RS07250	COG1917	Cupin 2, conserved barrel domain protein
MG068_RS07250	COG4977	sequence-specific DNA binding
MG068_RS07255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MG068_RS07275	COG0348	domain, Protein
MG068_RS07290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MG068_RS07305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MG068_RS07310	COG0069	glutamate synthase activity
MG068_RS07340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG068_RS07355	COG1253	flavin adenine dinucleotide binding
MG068_RS07375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG068_RS07390	COG0504	CTP synthase activity
MG068_RS07395	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MG068_RS07410	COG0148	phosphopyruvate hydratase activity
MG068_RS07415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MG068_RS07420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MG068_RS07425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MG068_RS07435	COG2840	Smr protein MutS2
MG068_RS07440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MG068_RS07445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MG068_RS07470	COG1534	Rna-binding protein
MG068_RS07475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MG068_RS07480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MG068_RS07505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MG068_RS07510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MG068_RS07515	COG1923	regulation of RNA biosynthetic process
MG068_RS07520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MG068_RS07525	COG1546	Belongs to the CinA family
MG068_RS07530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MG068_RS07535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MG068_RS07540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MG068_RS07545	COG2137	regulation of response to DNA damage stimulus
MG068_RS07550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MG068_RS07555	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MG068_RS07580	COG4773	Receptor
MG068_RS07595	COG1940	carbohydrate kinase activity
MG068_RS07635	COG3540	Alkaline phosphatase
MG068_RS07655	COG3258	Cytochrome c
MG068_RS07670	COG2223	nitrite transmembrane transporter activity
MG068_RS07685	COG1741	Belongs to the pirin family
MG068_RS07690	COG0583	DNA-binding transcription factor activity
MG068_RS07720	COG0352	thiamine-phosphate diphosphorylase activity
MG068_RS07720	COG0351	phosphomethylpyrimidine kinase
MG068_RS07735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MG068_RS07740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MG068_RS07750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MG068_RS07760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MG068_RS07765	COG0477	Major facilitator Superfamily
MG068_RS07780	COG0617	tRNA 3'-terminal CCA addition
MG068_RS07790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MG068_RS07795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MG068_RS07805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MG068_RS07810	COG0166	Belongs to the GPI family
MG068_RS07825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MG068_RS07835	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MG068_RS07840	COG0671	phosphoesterase, PA-phosphatase related
MG068_RS07850	COG0800	Aldolase
MG068_RS07855	COG0129	dihydroxy-acid dehydratase activity
MG068_RS07865	COG0837	glucose binding
MG068_RS07890	COG2009	succinate dehydrogenase
MG068_RS07895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MG068_RS07900	COG1053	succinate dehydrogenase
MG068_RS07920	COG4591	ABC-type transport system involved in lipoprotein release permease component
MG068_RS07935	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MG068_RS07945	COG0552	protein localization to endoplasmic reticulum
MG068_RS07965	COG0742	ribosomal rna small subunit methyltransferase
MG068_RS07970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MG068_RS07980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MG068_RS07985	COG0405	Gamma-glutamyltransferase
MG068_RS07990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG068_RS08000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MG068_RS08020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MG068_RS08025	COG0415	Belongs to the DNA photolyase family
MG068_RS08030	COG2885	chlorophyll binding
MG068_RS08035	COG0583	DNA-binding transcription factor activity
MG068_RS08130	COG1404	Belongs to the peptidase S8 family
MG068_RS08285	COG0305	Participates in initiation and elongation during chromosome replication
MG068_RS08525	COG0582	viral genome integration into host DNA
MG068_RS08550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MG068_RS08560	COG2914	Belongs to the UPF0125 (RnfH) family
MG068_RS08565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG068_RS08570	COG0735	belongs to the Fur family
MG068_RS08580	COG0583	DNA-binding transcription factor activity
MG068_RS08585	COG0497	DNA recombination
MG068_RS08590	COG1420	regulation of RNA biosynthetic process
MG068_RS08595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MG068_RS08600	COG0443	Heat shock 70 kDa protein
MG068_RS08605	COG0484	heat shock protein binding
MG068_RS08610	COG2207	Transcriptional regulator
MG068_RS08615	COG2223	nitrite transmembrane transporter activity
MG068_RS08625	COG0287	Prephenate dehydrogenase
MG068_RS08625	COG1605	Chorismate mutase
MG068_RS08635	COG1132	(ABC) transporter
MG068_RS08665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MG068_RS08670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MG068_RS08680	COG0343	queuine tRNA-ribosyltransferase activity
MG068_RS08685	COG1862	Preprotein translocase
MG068_RS08695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MG068_RS08705	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MG068_RS08715	COG2081	HI0933 family
MG068_RS08720	COG4681	YaeQ
MG068_RS08725	COG0564	pseudouridine synthase activity
MG068_RS08740	COG0625	glutathione transferase activity
MG068_RS08745	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MG068_RS08750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MG068_RS08755	COG0513	Belongs to the DEAD box helicase family
MG068_RS08765	COG0583	DNA-binding transcription factor activity
MG068_RS08770	COG0488	(ABC) transporter
MG068_RS08795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS08810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MG068_RS08815	COG2957	Belongs to the agmatine deiminase family
MG068_RS08825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MG068_RS08830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MG068_RS08840	COG0776	regulation of translation
MG068_RS08850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MG068_RS08865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MG068_RS08870	COG0183	Belongs to the thiolase family
MG068_RS08875	COG1024	Enoyl-CoA hydratase
MG068_RS08875	COG1250	3-hydroxyacyl-CoA dehydrogenase
MG068_RS08885	COG0105	UTP biosynthetic process
MG068_RS08890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MG068_RS08905	COG2976	Protein conserved in bacteria
MG068_RS08910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG068_RS08915	COG1160	GTP binding
MG068_RS08935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MG068_RS08940	COG0475	glutathione-regulated potassium exporter activity
MG068_RS08940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MG068_RS08960	COG0519	Catalyzes the synthesis of GMP from XMP
MG068_RS08960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MG068_RS08985	COG0583	DNA-binding transcription factor activity
MG068_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS09035	COG0640	Transcriptional regulator
MG068_RS09050	COG4716	Myosin-crossreactive antigen
MG068_RS09070	COG0431	NADPH-dependent FMN reductase
MG068_RS09080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG068_RS09085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG068_RS09090	COG1473	amidohydrolase
MG068_RS09100	COG1126	abc transporter atp-binding protein
MG068_RS09105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG068_RS09130	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MG068_RS09135	COG0583	DNA-binding transcription factor activity
MG068_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS09155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MG068_RS09175	COG1309	transcriptional regulator
MG068_RS09190	COG0697	spore germination
MG068_RS09195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MG068_RS09200	COG0167	dihydroorotate dehydrogenase activity
MG068_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS09220	COG1012	belongs to the aldehyde dehydrogenase family
MG068_RS09230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MG068_RS09235	COG3206	protein involved in exopolysaccharide biosynthesis
MG068_RS09235	COG0489	protein tyrosine kinase activity
MG068_RS09250	COG1045	serine acetyltransferase
MG068_RS09255	COG0438	transferase activity, transferring glycosyl groups
MG068_RS09265	COG0438	transferase activity, transferring glycosyl groups
MG068_RS09270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG068_RS09285	COG1596	polysaccharide export
MG068_RS09305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MG068_RS09335	COG0745	RESPONSE REGULATOR receiver
MG068_RS09340	COG0784	Response regulator, receiver
MG068_RS09340	COG4191	Histidine kinase
MG068_RS09345	COG2205	protein histidine kinase activity
MG068_RS09345	COG3437	response regulator, receiver
MG068_RS09345	COG3850	Histidine kinase
MG068_RS09345	COG4999	Histidine kinase
MG068_RS09350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MG068_RS09360	COG5002	protein histidine kinase activity
MG068_RS09370	COG0640	Transcriptional regulator
MG068_RS09405	COG0460	homoserine dehydrogenase
MG068_RS09405	COG0527	aspartate kinase activity
MG068_RS09410	COG0083	homoserine kinase activity
MG068_RS09420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG068_RS09425	COG0124	histidyl-tRNA synthetase
MG068_RS09440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MG068_RS09445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MG068_RS09450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MG068_RS09455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MG068_RS09455	COG0131	Imidazoleglycerol-phosphate dehydratase
MG068_RS09460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MG068_RS09465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MG068_RS09470	COG0107	imidazoleglycerol-phosphate synthase activity
MG068_RS09475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MG068_RS09475	COG0140	phosphoribosyl-ATP diphosphatase activity
MG068_RS09495	COG1446	asparaginase
MG068_RS09500	COG3142	Participates in the control of copper homeostasis
MG068_RS09520	COG0789	Transcriptional regulator
MG068_RS09535	COG3537	Alpha-1,2-mannosidase
MG068_RS09540	COG1609	Transcriptional regulator
MG068_RS09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG068_RS09570	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
MG068_RS09575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MG068_RS09580	COG0235	Class ii aldolase
MG068_RS09590	COG0531	amino acid
MG068_RS09595	COG0531	amino acid
MG068_RS09605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MG068_RS09610	COG0277	FAD linked oxidase domain protein
MG068_RS09625	COG2205	protein histidine kinase activity
MG068_RS09630	COG0745	RESPONSE REGULATOR receiver
MG068_RS09635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS09655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MG068_RS09675	COG1024	Enoyl-CoA hydratase
MG068_RS09700	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG068_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS09715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MG068_RS09720	COG0505	Belongs to the CarA family
MG068_RS09725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MG068_RS09730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MG068_RS09740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MG068_RS09750	COG4676	Protein conserved in bacteria
MG068_RS09770	COG3279	Response regulator of the LytR AlgR family
MG068_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
MG068_RS09805	COG2205	protein histidine kinase activity
MG068_RS09805	COG0784	Response regulator, receiver
MG068_RS09805	COG2198	Histidine kinase
MG068_RS09810	COG1024	Enoyl-CoA hydratase
MG068_RS09815	COG0318	PFAM AMP-dependent synthetase and ligase
MG068_RS09820	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MG068_RS09825	COG1012	belongs to the aldehyde dehydrogenase family
MG068_RS09830	COG1309	transcriptional regulator
MG068_RS09835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MG068_RS09875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MG068_RS09890	COG0840	transmembrane signaling receptor activity
MG068_RS09900	COG0835	chemotaxis
MG068_RS09905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MG068_RS09910	COG0840	transmembrane signaling receptor activity
MG068_RS09920	COG0745	RESPONSE REGULATOR receiver
MG068_RS09930	COG0835	chemotaxis
MG068_RS09940	COG1360	Flagellar Motor Protein
MG068_RS09945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MG068_RS09950	COG0643	Histidine kinase
MG068_RS09950	COG2198	Histidine kinase
MG068_RS09950	COG0784	Response regulator, receiver
MG068_RS09955	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MG068_RS09980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MG068_RS09985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MG068_RS10000	COG1987	bacterial-type flagellum assembly
MG068_RS10010	COG3190	flagellar
MG068_RS10060	COG1677	Flagellar hook-basal body complex protein FliE
MG068_RS10090	COG2197	response regulator
MG068_RS10145	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MG068_RS10155	COG4787	bacterial-type flagellum-dependent cell motility
MG068_RS10170	COG1558	bacterial-type flagellum-dependent cell motility
MG068_RS10175	COG1815	bacterial-type flagellum-dependent cell motility
MG068_RS10180	COG0784	Response regulator, receiver
MG068_RS10180	COG0835	chemotaxis
MG068_RS10200	COG5002	protein histidine kinase activity
MG068_RS10250	COG2915	High frequency lysogenization protein hflD homolog
MG068_RS10255	COG0482	sulfurtransferase activity
MG068_RS10270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MG068_RS10280	COG0542	response to heat
MG068_RS10290	COG3093	addiction module antidote protein HigA
MG068_RS10325	COG0492	ferredoxin-NADP+ reductase activity
MG068_RS10330	COG1674	ftsk spoiiie
MG068_RS10340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MG068_RS10350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MG068_RS10365	COG2819	hydrolase of the alpha beta superfamily
MG068_RS10375	COG4558	Periplasmic binding protein
MG068_RS10380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG068_RS10385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MG068_RS10395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MG068_RS10410	COG0784	Response regulator, receiver
MG068_RS10410	COG5002	protein histidine kinase activity
MG068_RS10415	COG2197	response regulator
MG068_RS10445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MG068_RS10455	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MG068_RS10470	COG1595	DNA-templated transcription, initiation
MG068_RS10490	COG0784	Response regulator, receiver
MG068_RS10495	COG4251	negative regulation of phosphorylation
MG068_RS10505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MG068_RS10515	COG0454	-acetyltransferase
MG068_RS10515	COG0456	acetyltransferase
MG068_RS10590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MG068_RS10595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MG068_RS10600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MG068_RS10605	COG2080	2 iron, 2 sulfur cluster binding
MG068_RS10620	COG1764	response to oxidative stress
MG068_RS10630	COG0583	DNA-binding transcription factor activity
MG068_RS10650	COG1595	DNA-templated transcription, initiation
MG068_RS10655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG068_RS10665	COG1309	transcriptional regulator
MG068_RS10750	COG0649	NAD binding
MG068_RS10760	COG1609	Transcriptional regulator
MG068_RS10765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG068_RS10765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MG068_RS10770	COG1105	Belongs to the carbohydrate kinase PfkB family
MG068_RS10775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG068_RS10775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG068_RS10795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MG068_RS10800	COG0583	DNA-binding transcription factor activity
MG068_RS10815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MG068_RS10840	COG5265	(ABC) transporter
MG068_RS10845	COG4206	TonB-dependent receptor
MG068_RS10860	COG4555	ABC transporter
MG068_RS10880	COG2207	Transcriptional regulator
MG068_RS10905	COG0642	Histidine kinase
MG068_RS10915	COG0318	PFAM AMP-dependent synthetase and ligase
MG068_RS10925	COG2186	Transcriptional regulator
MG068_RS10945	COG2271	Major facilitator Superfamily
MG068_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS10990	COG0583	DNA-binding transcription factor activity
MG068_RS10995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MG068_RS11015	COG0583	DNA-binding transcription factor activity
MG068_RS11040	COG2204	response regulator
MG068_RS11135	COG5002	protein histidine kinase activity
MG068_RS11135	COG5001	Diguanylate cyclase
MG068_RS11135	COG3447	MASE1 domain protein
MG068_RS11140	COG1136	(ABC) transporter
MG068_RS11140	COG0577	efflux transmembrane transporter activity
MG068_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS11155	COG0745	RESPONSE REGULATOR receiver
MG068_RS11160	COG2205	protein histidine kinase activity
MG068_RS11180	COG4774	siderophore transport
MG068_RS11200	COG3214	Protein conserved in bacteria
MG068_RS11210	COG4774	siderophore transport
MG068_RS11260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MG068_RS11265	COG1285	pathogenesis
MG068_RS11270	COG4191	Histidine kinase
MG068_RS11275	COG4566	intracellular signal transduction
MG068_RS11325	COG0243	molybdopterin cofactor binding
MG068_RS11330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MG068_RS11375	COG1136	(ABC) transporter
MG068_RS11390	COG4771	TonB-dependent receptor
MG068_RS11415	COG5002	protein histidine kinase activity
MG068_RS11420	COG0583	DNA-binding transcription factor activity
MG068_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS11450	COG0642	Histidine kinase
MG068_RS11455	COG3537	Alpha-1,2-mannosidase
MG068_RS11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG068_RS11475	COG0477	Major facilitator Superfamily
MG068_RS11495	COG2202	Pas domain
MG068_RS11495	COG3920	Histidine kinase
MG068_RS11540	COG1335	isochorismatase
MG068_RS11545	COG1335	isochorismatase
MG068_RS11555	COG0488	(ABC) transporter
MG068_RS11580	COG0811	peptide transport
MG068_RS11705	COG0840	transmembrane signaling receptor activity
MG068_RS11715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MG068_RS11720	COG4149	molybdate abc transporter
MG068_RS11725	COG0725	ABC transporter, periplasmic molybdate-binding protein
MG068_RS11730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG068_RS11745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MG068_RS11750	COG2181	nitrate reductase activity
MG068_RS11755	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MG068_RS11760	COG1140	nitrate reductase beta subunit
MG068_RS11765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MG068_RS11770	COG2223	nitrite transmembrane transporter activity
MG068_RS11780	COG0746	molybdenum cofactor guanylyltransferase activity
MG068_RS11785	COG0314	molybdopterin synthase activity
MG068_RS11795	COG0303	'Molybdopterin
MG068_RS11800	COG0315	cyclic pyranopterin monophosphate synthase activity
MG068_RS11800	COG0521	Mo-molybdopterin cofactor biosynthetic process
MG068_RS11805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MG068_RS11855	COG0789	Transcriptional regulator
MG068_RS11860	COG4771	TonB-dependent receptor
MG068_RS11865	COG0431	NADPH-dependent FMN reductase
MG068_RS11880	COG0798	PFAM Bile acid sodium symporter
MG068_RS11955	COG1943	Transposase
MG068_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS11965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MG068_RS11965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG068_RS11970	COG3433	isochorismatase activity
MG068_RS11970	COG1535	isochorismatase
MG068_RS11975	COG3433	isochorismatase activity
MG068_RS11975	COG1535	isochorismatase
MG068_RS11980	COG1021	2,3-dihydroxybenzoate-AMP ligase
MG068_RS11995	COG2409	Drug exporters of the RND superfamily
MG068_RS12000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG068_RS12060	COG1321	iron dependent repressor
MG068_RS12065	COG1914	H( )-stimulated, divalent metal cation uptake system
MG068_RS12080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MG068_RS12085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MG068_RS12095	COG4206	TonB-dependent receptor
MG068_RS12100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MG068_RS12145	COG4772	TonB-dependent receptor
MG068_RS12165	COG2226	methyltransferase
MG068_RS12210	COG4964	Belongs to the GSP D family
MG068_RS12265	COG2814	Major facilitator Superfamily
MG068_RS12275	COG1228	amidohydrolase
MG068_RS12285	COG1335	isochorismatase
MG068_RS12300	COG3850	Histidine kinase
MG068_RS12305	COG2197	response regulator
MG068_RS12315	COG2814	Major facilitator Superfamily
MG068_RS12325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MG068_RS12335	COG0583	DNA-binding transcription factor activity
MG068_RS12350	COG3161	chorismate lyase activity
MG068_RS12390	COG0277	FAD linked oxidase domain protein
MG068_RS12395	COG1304	FMN binding
MG068_RS12400	COG2186	Transcriptional regulator
MG068_RS12415	COG1285	pathogenesis
MG068_RS12500	COG0587	DNA-directed DNA polymerase activity
MG068_RS12515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MG068_RS12520	COG0519	Catalyzes the synthesis of GMP from XMP
MG068_RS12520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MG068_RS12535	COG1595	DNA-templated transcription, initiation
MG068_RS12545	COG1629	transport
MG068_RS12545	COG4206	TonB-dependent receptor
MG068_RS12575	COG0531	amino acid
MG068_RS12590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG068_RS12600	COG0789	Transcriptional regulator
MG068_RS12695	COG3447	MASE1 domain protein
MG068_RS12695	COG5002	protein histidine kinase activity
MG068_RS12695	COG5001	Diguanylate cyclase
MG068_RS12700	COG2183	response to ionizing radiation
MG068_RS12715	COG1983	PspC domain protein
MG068_RS12725	COG3243	poly(R)-hydroxyalkanoic acid synthase
MG068_RS12740	COG1073	alpha beta
MG068_RS12740	COG2226	methyltransferase
MG068_RS12745	COG0534	Mate efflux family protein
MG068_RS12765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MG068_RS12775	COG0668	transmembrane transport
MG068_RS12780	COG1902	pentaerythritol trinitrate reductase activity
MG068_RS12790	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MG068_RS12795	COG0590	tRNA wobble adenosine to inosine editing
MG068_RS12800	COG1733	regulation of RNA biosynthetic process
MG068_RS12805	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG068_RS12900	COG3702	type iv secretory pathway
MG068_RS12920	COG2948	multi-organism process
MG068_RS12930	COG3736	Type IV secretory pathway, component VirB8
MG068_RS12950	COG2814	Major facilitator Superfamily
MG068_RS12955	COG0789	Transcriptional regulator
MG068_RS12960	COG1902	pentaerythritol trinitrate reductase activity
MG068_RS12960	COG0446	pyridine nucleotide-disulphide oxidoreductase
MG068_RS12990	COG0784	Response regulator, receiver
MG068_RS12990	COG4191	Histidine kinase
MG068_RS13005	COG4774	siderophore transport
MG068_RS13015	COG0745	RESPONSE REGULATOR receiver
MG068_RS13035	COG0577	efflux transmembrane transporter activity
MG068_RS13035	COG1136	(ABC) transporter
MG068_RS13065	COG1733	regulation of RNA biosynthetic process
MG068_RS13070	COG0604	alcohol dehydrogenase
MG068_RS13085	COG0210	DNA helicase
MG068_RS13155	COG0583	DNA-binding transcription factor activity
MG068_RS13160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MG068_RS13170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MG068_RS13185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MG068_RS13190	COG0077	Prephenate dehydratase
MG068_RS13190	COG1605	Chorismate mutase
MG068_RS13195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MG068_RS13240	COG1228	amidohydrolase
MG068_RS13255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MG068_RS13295	COG2957	Belongs to the agmatine deiminase family
MG068_RS13300	COG0583	DNA-binding transcription factor activity
MG068_RS13380	COG4993	Dehydrogenase
MG068_RS13390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MG068_RS13400	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MG068_RS13410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MG068_RS13415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MG068_RS13430	COG0359	binds to the 23S rRNA
MG068_RS13435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MG068_RS13440	COG0360	Binds together with S18 to 16S ribosomal RNA
MG068_RS13450	COG0316	Belongs to the HesB IscA family
MG068_RS13455	COG0017	Asparaginyl-tRNA synthetase
MG068_RS13475	COG0288	reversible hydration of carbon dioxide
MG068_RS13485	COG3844	kynureninase activity
MG068_RS13490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG068_RS13495	COG2925	Exonuclease
MG068_RS13505	COG0667	Aldo Keto reductase
MG068_RS13525	COG2902	Dehydrogenase
MG068_RS13535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS13540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS13555	COG1960	acyl-CoA dehydrogenase activity
MG068_RS13570	COG1410	methionine synthase
MG068_RS13570	COG0646	methionine synthase
MG068_RS13575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MG068_RS13575	COG2755	lipolytic protein G-D-S-L family
MG068_RS13585	COG2900	Belongs to the SlyX family
MG068_RS13600	COG0386	Belongs to the glutathione peroxidase family
MG068_RS13610	COG1725	Transcriptional regulator
MG068_RS13615	COG1131	(ABC) transporter
MG068_RS13640	COG0114	fumarate hydratase activity
MG068_RS13655	COG2850	peptidyl-arginine hydroxylation
MG068_RS13665	COG0567	Dehydrogenase, E1 component
MG068_RS13690	COG3540	Alkaline phosphatase
MG068_RS13700	COG0305	Participates in initiation and elongation during chromosome replication
MG068_RS13720	COG0625	glutathione transferase activity
MG068_RS13740	COG0084	hydrolase, TatD family'
MG068_RS13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MG068_RS13780	COG0625	glutathione transferase activity
MG068_RS13800	COG1595	DNA-templated transcription, initiation
MG068_RS13805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MG068_RS13825	COG0386	Belongs to the glutathione peroxidase family
MG068_RS13830	COG0339	signal peptide processing
MG068_RS13835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MG068_RS13850	COG0705	Rhomboid family
MG068_RS13855	COG3104	oligopeptide transport
MG068_RS13865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MG068_RS13870	COG4290	ribonuclease
MG068_RS13885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MG068_RS13885	COG0316	Belongs to the HesB IscA family
MG068_RS13890	COG2154	pterin-4-alpha-carbinolamine dehydratase
MG068_RS13900	COG0428	transporter
MG068_RS13910	COG1530	ribonuclease E activity
MG068_RS13925	COG0395	ABC-type sugar transport system, permease component
MG068_RS13950	COG1609	Transcriptional regulator
MG068_RS13955	COG0271	Belongs to the BolA IbaG family
MG068_RS13960	COG2350	Protein conserved in bacteria
MG068_RS13965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MG068_RS13970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MG068_RS13975	COG1187	pseudouridine synthase activity
MG068_RS13985	COG2814	Major facilitator Superfamily
MG068_RS14005	COG0436	Aminotransferase
MG068_RS14010	COG4133	protoheme IX ABC transporter activity
MG068_RS14030	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MG068_RS14045	COG4235	cytochrome complex assembly
MG068_RS14045	COG3088	subunit of a heme lyase
MG068_RS14055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MG068_RS14065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MG068_RS14070	COG4988	ABC transporter
MG068_RS14080	COG1294	oxidase, subunit
MG068_RS14110	COG1649	PFAM Uncharacterised BCR, COG1649
MG068_RS14110	COG0726	polysaccharide deacetylase
MG068_RS14115	COG1215	transferase activity, transferring glycosyl groups
MG068_RS14125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MG068_RS14140	COG0165	Argininosuccinate lyase
MG068_RS14145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MG068_RS14155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MG068_RS14160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG068_RS14165	COG0137	argininosuccinate synthase activity
MG068_RS14170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MG068_RS14185	COG2166	iron-sulfur cluster assembly
MG068_RS14205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MG068_RS14225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MG068_RS14230	COG0402	S-adenosylhomocysteine deaminase activity
MG068_RS14235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MG068_RS14240	COG1509	lysine 2,3-aminomutase activity
MG068_RS14245	COG5001	Diguanylate cyclase
MG068_RS14245	COG3300	MHYT domain
MG068_RS14265	COG0501	Belongs to the peptidase M48B family
MG068_RS14275	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS14295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MG068_RS14305	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG068_RS14310	COG0802	atpase or kinase
MG068_RS14315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MG068_RS14315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MG068_RS14320	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MG068_RS14325	COG1570	exodeoxyribonuclease VII activity
MG068_RS14335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MG068_RS14350	COG4771	TonB-dependent receptor
MG068_RS14370	COG2169	Transcriptional regulator
MG068_RS14370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MG068_RS14375	COG2130	NADP-dependent
MG068_RS14400	COG1960	acyl-CoA dehydrogenase activity
MG068_RS14410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MG068_RS14440	COG1309	transcriptional regulator
MG068_RS14445	COG2076	Multidrug Resistance protein
MG068_RS14450	COG5487	UPF0391 membrane protein
MG068_RS14455	COG1280	lysine exporter protein (LysE YggA)
MG068_RS14460	COG0740	serine-type endopeptidase activity
MG068_RS14475	COG1794	racemase activity, acting on amino acids and derivatives
MG068_RS14510	COG0776	regulation of translation
MG068_RS14515	COG0072	phenylalanine-tRNA ligase activity
MG068_RS14515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG068_RS14520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MG068_RS14525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MG068_RS14530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MG068_RS14535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MG068_RS14540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MG068_RS14575	COG1185	polyribonucleotide nucleotidyltransferase activity
MG068_RS14580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MG068_RS14590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MG068_RS14595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MG068_RS14600	COG0195	Participates in both transcription termination and antitermination
MG068_RS14605	COG0779	Required for maturation of 30S ribosomal subunits
MG068_RS14620	COG1007	ATP synthesis coupled electron transport
MG068_RS14635	COG0713	ATP synthesis coupled electron transport
MG068_RS14645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MG068_RS14650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MG068_RS14665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MG068_RS14670	COG0649	NAD binding
MG068_RS14675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MG068_RS14680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MG068_RS14685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MG068_RS14700	COG0149	triose-phosphate isomerase activity
MG068_RS14715	COG3119	arylsulfatase activity
MG068_RS14720	COG0438	transferase activity, transferring glycosyl groups
MG068_RS14725	COG0726	polysaccharide deacetylase
MG068_RS14730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MG068_RS14735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MG068_RS14740	COG0159	tryptophan synthase activity
MG068_RS14750	COG0133	tryptophan synthase activity
MG068_RS14770	COG0135	phosphoribosylanthranilate isomerase activity
MG068_RS14775	COG0101	tRNA pseudouridine synthase activity
MG068_RS14790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MG068_RS14795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MG068_RS14800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MG068_RS14805	COG2890	protein-(glutamine-N5) methyltransferase activity
MG068_RS14810	COG1999	signal sequence binding
MG068_RS14815	COG0688	phosphatidylethanolamine metabolic process
MG068_RS14830	COG0433	COG0433 Predicted ATPase
MG068_RS14835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MG068_RS14845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MG068_RS14865	COG0412	Dienelactone hydrolase
MG068_RS14875	COG0717	Belongs to the dCTP deaminase family
MG068_RS14880	COG0489	protein tyrosine kinase activity
MG068_RS14885	COG4771	TonB-dependent receptor
MG068_RS14890	COG4771	TonB-dependent receptor
MG068_RS14910	COG3590	peptidase
MG068_RS14940	COG0697	spore germination
MG068_RS14950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG068_RS14955	COG2311	Membrane
MG068_RS14960	COG1047	Peptidyl-prolyl cis-trans
MG068_RS14965	COG0791	NLP P60 protein
MG068_RS14970	COG0791	NLP P60 protein
MG068_RS14975	COG1301	dicarboxylic acid transport
MG068_RS14995	COG1722	exodeoxyribonuclease VII activity
MG068_RS15000	COG0142	geranyltranstransferase activity
MG068_RS15010	COG0312	modulator of DNA gyrase
MG068_RS15015	COG3028	Belongs to the UPF0307 family
MG068_RS15020	COG0312	modulator of DNA gyrase
MG068_RS15040	COG2968	Membrane
MG068_RS15050	COG4771	TonB-dependent receptor
MG068_RS15065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MG068_RS15075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MG068_RS15090	COG0495	leucyl-tRNA aminoacylation
MG068_RS15100	COG3118	belongs to the thioredoxin family
MG068_RS15110	COG2203	Gaf domain
MG068_RS15110	COG4251	negative regulation of phosphorylation
MG068_RS15110	COG3706	GGDEF domain
MG068_RS15110	COG5001	Diguanylate cyclase
MG068_RS15115	COG1943	Transposase
MG068_RS15140	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MG068_RS15150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG068_RS15155	COG0346	lactoylglutathione lyase activity
MG068_RS15165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG068_RS15165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG068_RS15175	COG2878	Part of a membrane complex involved in electron transport
MG068_RS15180	COG0251	oxidation-reduction process
MG068_RS15185	COG0392	lysyltransferase activity
MG068_RS15185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MG068_RS15215	COG2824	Alkylphosphonate utilization operon protein PhnA
MG068_RS15220	COG0443	Heat shock 70 kDa protein
MG068_RS15265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MG068_RS15270	COG3122	Protein conserved in bacteria
MG068_RS15275	COG1451	nucleotide metabolic process
MG068_RS15285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG068_RS15305	COG0183	Belongs to the thiolase family
MG068_RS15320	COG1960	acyl-CoA dehydrogenase activity
MG068_RS15330	COG1793	dna ligase
MG068_RS15335	COG1201	RNA secondary structure unwinding
MG068_RS15350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG068_RS15355	COG1278	Cold shock
MG068_RS15360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MG068_RS15365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MG068_RS15370	COG1472	Belongs to the glycosyl hydrolase 3 family
MG068_RS15375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MG068_RS15380	COG2954	triphosphatase activity
MG068_RS15385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MG068_RS15390	COG0745	RESPONSE REGULATOR receiver
MG068_RS15395	COG1381	Involved in DNA repair and RecF pathway recombination
MG068_RS15400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MG068_RS15415	COG0681	Belongs to the peptidase S26 family
MG068_RS15420	COG0481	GTPase activity
MG068_RS15425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG068_RS15445	COG1741	Belongs to the pirin family
MG068_RS15450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MG068_RS15460	COG1741	Belongs to the pirin family
MG068_RS15470	COG1966	Carbon starvation protein
MG068_RS15475	COG2879	small protein
MG068_RS15490	COG2205	protein histidine kinase activity
MG068_RS15495	COG0745	RESPONSE REGULATOR receiver
MG068_RS15535	COG2814	Major facilitator Superfamily
MG068_RS15540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MG068_RS15540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MG068_RS15550	COG1113	amino acid transport
MG068_RS15555	COG1917	Cupin 2, conserved barrel domain protein
MG068_RS15555	COG2207	Transcriptional regulator
MG068_RS15575	COG1376	ErfK ybiS ycfS ynhG family protein
MG068_RS15580	COG0739	heme binding
MG068_RS15590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MG068_RS15600	COG0330	HflC and HflK could
MG068_RS15605	COG0330	HflC and HflK could
MG068_RS15610	COG0604	alcohol dehydrogenase
MG068_RS15625	COG0678	peroxiredoxin activity
MG068_RS15635	COG4953	penicillin-binding protein 1C
MG068_RS15640	COG2373	Large extracellular alpha-helical protein
MG068_RS15645	COG2079	MmgE PrpD family protein
MG068_RS15650	COG2828	Protein conserved in bacteria
MG068_RS15660	COG3609	addiction module antidote protein, CC2985 family
MG068_RS15690	COG0259	pyridoxamine-phosphate oxidase activity
MG068_RS15705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MG068_RS15725	COG0477	Major facilitator Superfamily
MG068_RS15750	COG3038	cytochrome b561
MG068_RS15765	COG1760	l-serine dehydratase
MG068_RS15770	COG2267	carboxylic ester hydrolase activity
MG068_RS15775	COG0460	homoserine dehydrogenase
MG068_RS15775	COG0527	aspartate kinase activity
MG068_RS15780	COG0626	cystathionine gamma-synthase activity
MG068_RS15785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MG068_RS15790	COG0739	heme binding
MG068_RS15795	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MG068_RS15800	COG1272	protein, Hemolysin III
MG068_RS15815	COG0463	Glycosyl transferase, family 2
MG068_RS15820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG068_RS15825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MG068_RS15840	COG1309	transcriptional regulator
MG068_RS15850	COG1960	acyl-CoA dehydrogenase activity
MG068_RS15885	COG0583	DNA-binding transcription factor activity
MG068_RS15900	COG0509	glycine decarboxylation via glycine cleavage system
MG068_RS15905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MG068_RS15915	COG0330	HflC and HflK could
MG068_RS15925	COG1742	UPF0060 membrane protein
MG068_RS15930	COG3956	TIGRFAM MazG family protein
MG068_RS15935	COG1218	3'(2'),5'-bisphosphate nucleotidase
MG068_RS15940	COG0494	nUDIX hydrolase
MG068_RS15950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MG068_RS15970	COG0840	transmembrane signaling receptor activity
MG068_RS15975	COG0835	chemotaxis
MG068_RS15990	COG0189	ligase activity
MG068_RS16005	COG1199	ATP-dependent helicase activity
MG068_RS16015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG068_RS16035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MG068_RS16045	COG1643	Atp-dependent helicase
MG068_RS16050	COG0783	Belongs to the Dps family
MG068_RS16055	COG0514	ATP-dependent DNA helicase (RecQ)
MG068_RS16125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MG068_RS16130	COG0602	queuosine metabolic process
MG068_RS16140	COG2885	chlorophyll binding
MG068_RS16145	COG0823	Involved in the tonB-independent uptake of proteins
MG068_RS16160	COG0811	peptide transport
MG068_RS16165	COG0824	Thioesterase
MG068_RS16170	COG2255	four-way junction helicase activity
MG068_RS16180	COG0632	four-way junction helicase activity
MG068_RS16185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MG068_RS16190	COG0217	transcriptional regulatory protein
MG068_RS16210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MG068_RS16240	COG0488	(ABC) transporter
MG068_RS16250	COG4651	solute:proton antiporter activity
MG068_RS16250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MG068_RS16265	COG0745	RESPONSE REGULATOR receiver
MG068_RS16270	COG2205	protein histidine kinase activity
MG068_RS16280	COG0542	response to heat
MG068_RS16305	COG0028	Belongs to the TPP enzyme family
MG068_RS16330	COG3387	PFAM Glycoside hydrolase 15-related
MG068_RS16335	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MG068_RS16340	COG3011	Protein conserved in bacteria
MG068_RS16355	COG0564	pseudouridine synthase activity
MG068_RS16360	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG068_RS16370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MG068_RS16370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MG068_RS16380	COG0045	succinate-CoA ligase (ADP-forming) activity
MG068_RS16410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MG068_RS16420	COG2205	protein histidine kinase activity
MG068_RS16425	COG0745	RESPONSE REGULATOR receiver
MG068_RS16440	COG0189	ligase activity
MG068_RS16465	COG3152	Membrane
MG068_RS16510	COG2022	thiamine diphosphate biosynthetic process
MG068_RS16515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MG068_RS16520	COG0471	metal ion transport
MG068_RS16520	COG3273	potassium ion transport
MG068_RS16540	COG1970	mechanosensitive ion channel activity
MG068_RS16555	COG1115	amino acid carrier protein
MG068_RS16560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG068_RS16565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS16570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS16595	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MG068_RS16605	COG3588	fructose-bisphosphate aldolase
MG068_RS16610	COG0469	pyruvate kinase activity
MG068_RS16620	COG0126	phosphoglycerate kinase activity
MG068_RS16635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MG068_RS16640	COG3047	cAMP biosynthetic process
MG068_RS16685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MG068_RS16690	COG1301	dicarboxylic acid transport
MG068_RS16700	COG2304	oxidoreductase activity
MG068_RS16720	COG0714	Associated with various cellular activities
MG068_RS16750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MG068_RS16770	COG5295	Hep Hag repeat protein
MG068_RS16810	COG0254	rRNA binding
MG068_RS16825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MG068_RS16835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MG068_RS16840	COG1758	RNA polymerase activity
MG068_RS16850	COG3383	formate dehydrogenase (NAD+) activity
MG068_RS16850	COG0243	molybdopterin cofactor binding
MG068_RS16855	COG0243	molybdopterin cofactor binding
MG068_RS16855	COG3383	formate dehydrogenase (NAD+) activity
MG068_RS16860	COG0437	4 iron, 4 sulfur cluster binding
MG068_RS16865	COG2864	formate dehydrogenase
MG068_RS16875	COG1921	L-seryl-tRNASec selenium transferase activity
MG068_RS16880	COG3276	selenocysteine insertion sequence binding
MG068_RS16890	COG0709	Synthesizes selenophosphate from selenide and ATP
MG068_RS16905	COG1561	YicC-like family, N-terminal region
MG068_RS16910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MG068_RS16915	COG0346	lactoylglutathione lyase activity
MG068_RS16925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MG068_RS16940	COG0006	proline dipeptidase activity
MG068_RS16945	COG0006	proline dipeptidase activity
MG068_RS16950	COG3079	Belongs to the UPF0149 family
MG068_RS16970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MG068_RS16980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MG068_RS16990	COG2912	Transglutaminase-like superfamily
MG068_RS16995	COG1773	rubredoxin
MG068_RS17005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MG068_RS17020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MG068_RS17025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG068_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS17065	COG0671	phosphoesterase, PA-phosphatase related
MG068_RS17075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MG068_RS17080	COG0563	adenylate kinase activity
MG068_RS17105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MG068_RS17115	COG0848	biopolymer transport protein
MG068_RS17125	COG2832	Protein of unknown function (DUF454)
MG068_RS17160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MG068_RS17185	COG0745	RESPONSE REGULATOR receiver
MG068_RS17195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MG068_RS17200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MG068_RS17205	COG0405	Gamma-glutamyltransferase
MG068_RS17210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MG068_RS17225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MG068_RS17230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MG068_RS17235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MG068_RS17250	COG0473	3-isopropylmalate dehydrogenase activity
MG068_RS17265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS17285	COG1538	Outer membrane efflux protein
MG068_RS17290	COG0531	amino acid
MG068_RS17295	COG1519	Transferase
MG068_RS17300	COG1560	Kdo2-lipid A biosynthetic process
MG068_RS17340	COG1301	dicarboxylic acid transport
MG068_RS17350	COG4191	Histidine kinase
MG068_RS17365	COG0642	Histidine kinase
MG068_RS17380	COG2851	Citrate transporter
MG068_RS17385	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS17410	COG1162	GTPase activity
MG068_RS17415	COG0436	Aminotransferase
MG068_RS17435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MG068_RS17450	COG1228	amidohydrolase
MG068_RS17455	COG0804	urea catabolic process
MG068_RS17465	COG1307	EDD domain protein, DegV family
MG068_RS17510	COG3706	GGDEF domain
MG068_RS17510	COG2203	Gaf domain
MG068_RS17510	COG5001	Diguanylate cyclase
MG068_RS17510	COG4251	negative regulation of phosphorylation
MG068_RS17515	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MG068_RS17525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MG068_RS17535	COG4206	TonB-dependent receptor
MG068_RS17545	COG1902	pentaerythritol trinitrate reductase activity
MG068_RS17570	COG0583	DNA-binding transcription factor activity
MG068_RS17575	COG1064	alcohol dehydrogenase
MG068_RS17615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MG068_RS17645	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MG068_RS17650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MG068_RS17660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MG068_RS17665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MG068_RS17680	COG1522	sequence-specific DNA binding
MG068_RS17690	COG4773	Receptor
MG068_RS17720	COG0617	tRNA 3'-terminal CCA addition
MG068_RS17750	COG3468	outer membrane autotransporter barrel domain protein
MG068_RS17760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MG068_RS17765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MG068_RS17770	COG1609	Transcriptional regulator
MG068_RS17780	COG0837	glucose binding
MG068_RS17790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MG068_RS17810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MG068_RS17820	COG4191	Histidine kinase
MG068_RS17825	COG0784	Response regulator, receiver
MG068_RS17830	COG4251	negative regulation of phosphorylation
MG068_RS17835	COG2823	Periplasmic or secreted lipoprotein
MG068_RS17840	COG0673	inositol 2-dehydrogenase activity
MG068_RS17845	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MG068_RS17865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MG068_RS17870	COG0321	lipoyl(octanoyl) transferase activity
MG068_RS17875	COG2921	Belongs to the UPF0250 family
MG068_RS17885	COG1686	Belongs to the peptidase S11 family
MG068_RS17890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MG068_RS17895	COG2951	lytic endotransglycosylase activity
MG068_RS17900	COG0772	Belongs to the SEDS family
MG068_RS17905	COG0772	Belongs to the SEDS family
MG068_RS17910	COG0768	penicillin binding
MG068_RS17920	COG1792	Involved in formation and maintenance of cell shape
MG068_RS17925	COG1077	Cell shape determining protein MreB Mrl
MG068_RS17930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG068_RS17945	COG0308	aminopeptidase N
MG068_RS17950	COG2226	methyltransferase
MG068_RS17980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS17985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS17995	COG0673	inositol 2-dehydrogenase activity
MG068_RS18005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MG068_RS18025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MG068_RS18035	COG2832	Protein of unknown function (DUF454)
MG068_RS18045	COG0436	Aminotransferase
MG068_RS18050	COG1505	serine-type exopeptidase activity
MG068_RS18075	COG0697	spore germination
MG068_RS18080	COG1666	GTP binding
MG068_RS18110	COG0339	signal peptide processing
MG068_RS18120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MG068_RS18140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MG068_RS18150	COG1136	(ABC) transporter
MG068_RS18155	COG1136	(ABC) transporter
MG068_RS18155	COG0577	efflux transmembrane transporter activity
MG068_RS18160	COG0577	efflux transmembrane transporter activity
MG068_RS18170	COG2204	response regulator
MG068_RS18175	COG4191	Histidine kinase
MG068_RS18185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MG068_RS18200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MG068_RS18205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MG068_RS18210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MG068_RS18215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MG068_RS18220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MG068_RS18225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MG068_RS18235	COG0356	it plays a direct role in the translocation of protons across the membrane
MG068_RS18250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MG068_RS18255	COG0508	dehydrogenase complex catalyzes the overall conversion of
MG068_RS18275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MG068_RS18300	COG0181	hydroxymethylbilane synthase activity
MG068_RS18310	COG0745	RESPONSE REGULATOR receiver
MG068_RS18310	COG2972	Histidine kinase
MG068_RS18330	COG4771	TonB-dependent receptor
MG068_RS18340	COG0840	transmembrane signaling receptor activity
MG068_RS18380	COG0477	Major facilitator Superfamily
MG068_RS18410	COG0583	DNA-binding transcription factor activity
MG068_RS18415	COG0477	Major facilitator Superfamily
MG068_RS18460	COG0625	glutathione transferase activity
MG068_RS18475	COG2259	Doxx family
MG068_RS18495	COG3550	peptidyl-serine autophosphorylation
MG068_RS18500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MG068_RS18505	COG1490	D-aminoacyl-tRNA deacylase activity
MG068_RS18550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MG068_RS18550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MG068_RS18555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MG068_RS18560	COG0242	peptide deformylase activity
MG068_RS18570	COG0758	DNA mediated transformation
MG068_RS18575	COG2922	Belongs to the Smg family
MG068_RS18585	COG1714	RDD family
MG068_RS18590	COG1754	DNA topoisomerase type I activity
MG068_RS18590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MG068_RS18595	COG0009	L-threonylcarbamoyladenylate synthase
MG068_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS18620	COG0616	signal peptide processing
MG068_RS18625	COG0534	Mate efflux family protein
MG068_RS18640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MG068_RS18645	COG0625	glutathione transferase activity
MG068_RS18655	COG1252	NADH dehydrogenase
MG068_RS18680	COG2860	membrane
MG068_RS18690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS18695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS18710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MG068_RS18730	COG1846	Transcriptional regulator
MG068_RS18740	COG0625	glutathione transferase activity
MG068_RS18755	COG0459	protein refolding
MG068_RS18760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MG068_RS18765	COG2356	endonuclease I
MG068_RS18770	COG1324	tolerance protein
MG068_RS18780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG068_RS18800	COG0840	transmembrane signaling receptor activity
MG068_RS18825	COG4585	Histidine kinase
MG068_RS18845	COG0583	DNA-binding transcription factor activity
MG068_RS18855	COG1785	Belongs to the alkaline phosphatase family
MG068_RS18860	COG1686	Belongs to the peptidase S11 family
MG068_RS18870	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG068_RS18880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MG068_RS18890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MG068_RS18900	COG0511	ligase activity, forming carbon-carbon bonds
MG068_RS18905	COG0439	Biotin carboxylase
MG068_RS18920	COG2264	protein methyltransferase activity
MG068_RS18930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MG068_RS18935	COG4589	Belongs to the CDS family
MG068_RS18940	COG0204	Acyl-transferase
MG068_RS18950	COG2453	phosphatase
MG068_RS18950	COG0671	phosphoesterase, PA-phosphatase related
MG068_RS18955	COG2267	carboxylic ester hydrolase activity
MG068_RS18960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MG068_RS18965	COG0138	bifunctional purine biosynthesis protein purh
MG068_RS18975	COG0151	Belongs to the GarS family
MG068_RS18990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MG068_RS19005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG068_RS19010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MG068_RS19015	COG2201	protein-glutamate methylesterase activity
MG068_RS19020	COG2177	Part of the ABC transporter FtsEX involved in
MG068_RS19025	COG2884	Cell division ATP-binding protein ftsE
MG068_RS19040	COG3118	belongs to the thioredoxin family
MG068_RS19045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MG068_RS19060	COG3706	GGDEF domain
MG068_RS19070	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MG068_RS19105	COG1652	LysM domain
MG068_RS19110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MG068_RS19110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MG068_RS19115	COG1473	amidohydrolase
MG068_RS19120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG068_RS19125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG068_RS19140	COG1289	transmembrane transporter activity
MG068_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS19150	COG2814	Major facilitator Superfamily
MG068_RS19180	COG0316	Belongs to the HesB IscA family
MG068_RS19220	COG1051	belongs to the nudix hydrolase family
MG068_RS19235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MG068_RS19240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MG068_RS19245	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MG068_RS19255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MG068_RS19260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG068_RS19265	COG0730	response to heat
MG068_RS19275	COG0134	indole-3-glycerol-phosphate synthase activity
MG068_RS19280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MG068_RS19310	COG1597	lipid kinase activity
MG068_RS19325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MG068_RS19330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MG068_RS19340	COG2111	Na H antiporter
MG068_RS19340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MG068_RS19345	COG1006	Multisubunit Na H antiporter MnhC subunit
MG068_RS19350	COG0651	ATP synthesis coupled electron transport
MG068_RS19355	COG1863	multisubunit Na H antiporter MnhE subunit
MG068_RS19360	COG2212	antiporter activity
MG068_RS19365	COG1320	monovalent cation:proton antiporter activity
MG068_RS19370	COG0530	calcium, potassium:sodium antiporter activity
MG068_RS19385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MG068_RS19400	COG4804	nuclease activity
MG068_RS19415	COG3104	oligopeptide transport
MG068_RS19420	COG3483	tryptophan 2,3-dioxygenase activity
MG068_RS19455	COG2378	regulation of single-species biofilm formation
MG068_RS19470	COG2354	Protein conserved in bacteria
MG068_RS19475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MG068_RS19490	COG3264	Mechanosensitive ion channel
MG068_RS19490	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MG068_RS19505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MG068_RS19545	COG1166	arginine decarboxylase activity
MG068_RS19550	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MG068_RS19570	COG2960	long-chain fatty acid transporting porin activity
MG068_RS19620	COG0577	efflux transmembrane transporter activity
MG068_RS19620	COG1136	(ABC) transporter
MG068_RS19625	COG1136	(ABC) transporter
MG068_RS19625	COG0577	efflux transmembrane transporter activity
MG068_RS19630	COG3842	ATPase activity
MG068_RS19635	COG0515	serine threonine protein kinase
MG068_RS19640	COG0606	chelatase, subunit chli
MG068_RS19655	COG0561	phosphatase activity
MG068_RS19660	COG3932	Exopolysaccharide synthesis, ExoD
MG068_RS19690	COG1999	signal sequence binding
MG068_RS19695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MG068_RS19700	COG1845	cytochrome c oxidase, subunit III
MG068_RS19710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MG068_RS19715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG068_RS19730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG068_RS19735	COG1104	cysteine desulfurase activity
MG068_RS19755	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MG068_RS19775	COG2031	fatty acid transporter
MG068_RS19790	COG4753	response regulator
MG068_RS19790	COG2207	Transcriptional regulator
MG068_RS19820	COG0673	inositol 2-dehydrogenase activity
MG068_RS19830	COG1501	Belongs to the glycosyl hydrolase 31 family
MG068_RS19835	COG2222	sugar isomerase
MG068_RS19840	COG1940	carbohydrate kinase activity
MG068_RS19850	COG1349	DNA-binding transcription factor activity
MG068_RS19855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MG068_RS19860	COG2814	Major facilitator Superfamily
MG068_RS19875	COG1040	competence protein
MG068_RS19895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MG068_RS19900	COG0156	8-amino-7-oxononanoate synthase activity
MG068_RS19905	COG2267	carboxylic ester hydrolase activity
MG068_RS19925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MG068_RS19945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MG068_RS19970	COG0714	Associated with various cellular activities
MG068_RS19980	COG0754	glutathionylspermidine amidase activity
MG068_RS19990	COG0129	dihydroxy-acid dehydratase activity
MG068_RS20000	COG1199	ATP-dependent helicase activity
MG068_RS20010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MG068_RS20030	COG3781	membrane
MG068_RS20060	COG0625	glutathione transferase activity
MG068_RS20080	COG2207	Transcriptional regulator
MG068_RS20095	COG4555	ABC transporter
MG068_RS20125	COG0543	2 iron, 2 sulfur cluster binding
MG068_RS20125	COG0633	Ferredoxin
MG068_RS20130	COG1131	(ABC) transporter
MG068_RS20135	COG0842	Transport permease protein
MG068_RS20145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MG068_RS20155	COG0084	hydrolase, TatD family'
MG068_RS20160	COG1643	Atp-dependent helicase
MG068_RS20170	COG1187	pseudouridine synthase activity
MG068_RS20185	COG0667	Aldo Keto reductase
MG068_RS20200	COG1690	Belongs to the RtcB family
MG068_RS20215	COG0840	transmembrane signaling receptor activity
MG068_RS20220	COG0583	DNA-binding transcription factor activity
MG068_RS20225	COG2814	Major facilitator Superfamily
MG068_RS20230	COG0656	L-ascorbic acid biosynthetic process
MG068_RS20235	COG2205	protein histidine kinase activity
MG068_RS20235	COG2198	Histidine kinase
MG068_RS20235	COG0784	Response regulator, receiver
MG068_RS20250	COG2267	carboxylic ester hydrolase activity
MG068_RS20255	COG0393	Putative heavy-metal-binding
MG068_RS20260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG068_RS20260	COG1042	CoA-binding domain protein
MG068_RS20260	COG0045	succinate-CoA ligase (ADP-forming) activity
MG068_RS20265	COG2239	Acts as a magnesium transporter
MG068_RS20285	COG3100	YcgL domain-containing protein
MG068_RS20295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MG068_RS20300	COG1028	Short-chain dehydrogenase reductase Sdr
MG068_RS20340	COG2986	histidine ammonia-lyase
MG068_RS20350	COG0463	Glycosyl transferase, family 2
MG068_RS20365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG068_RS20370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG068_RS20385	COG1294	oxidase, subunit
MG068_RS20390	COG1271	oxidase subunit
MG068_RS20410	COG1595	DNA-templated transcription, initiation
MG068_RS20445	COG0408	coproporphyrinogen oxidase activity
MG068_RS20450	COG2323	membrane
MG068_RS20465	COG0589	response to stress
MG068_RS20480	COG0210	DNA helicase
MG068_RS20495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG068_RS20500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MG068_RS20505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MG068_RS20510	COG1819	glycosyl
MG068_RS20525	COG0251	oxidation-reduction process
MG068_RS20560	COG0463	Glycosyl transferase, family 2
MG068_RS20575	COG1475	DNA binding
MG068_RS20580	COG1192	Involved in chromosome partitioning
MG068_RS20585	COG0357	Ribosomal RNA small subunit methyltransferase G
MG068_RS20590	COG2091	lysine biosynthetic process via aminoadipic acid
MG068_RS20635	COG1971	Probably functions as a manganese efflux pump
MG068_RS20640	COG2205	protein histidine kinase activity
MG068_RS20640	COG0784	Response regulator, receiver
MG068_RS20660	COG2911	Protein conserved in bacteria
MG068_RS20665	COG0729	surface antigen
MG068_RS20675	COG0752	glycyl-tRNA synthetase alpha subunit
MG068_RS20680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MG068_RS20685	COG0519	Catalyzes the synthesis of GMP from XMP
MG068_RS20685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MG068_RS20695	COG0805	protein transport
MG068_RS20705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MG068_RS20715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MG068_RS20725	COG0840	transmembrane signaling receptor activity
MG068_RS20755	COG3135	benzoate transporter
MG068_RS20770	COG2951	lytic endotransglycosylase activity
MG068_RS20775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MG068_RS20780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MG068_RS20785	COG3706	GGDEF domain
MG068_RS20815	COG0302	gtp cyclohydrolase
MG068_RS20830	COG1566	PFAM secretion protein HlyD family protein
MG068_RS20840	COG1289	transmembrane transporter activity
MG068_RS20855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MG068_RS20860	COG1074	ATP-dependent DNA helicase activity
MG068_RS20865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MG068_RS20870	COG1127	ABC transporter
MG068_RS20875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MG068_RS20880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MG068_RS20895	COG2853	Lipoprotein
MG068_RS20900	COG0386	Belongs to the glutathione peroxidase family
MG068_RS20910	COG1322	Protein conserved in bacteria
MG068_RS20920	COG0604	alcohol dehydrogenase
MG068_RS20925	COG0583	DNA-binding transcription factor activity
MG068_RS20945	COG0531	amino acid
MG068_RS20955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MG068_RS20965	COG0861	Integral membrane protein TerC family
MG068_RS20975	COG0584	glycerophosphoryl diester phosphodiesterase
MG068_RS20990	COG0706	membrane insertase activity
MG068_RS20995	COG0594	ribonuclease P activity
MG068_RS21000	COG0230	Belongs to the bacterial ribosomal protein bL34 family