locus-tag	class	description
HUT07_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUT07_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT07_RS00025	COG0187	DNA topoisomerase II activity
HUT07_RS00030	COG1266	CAAX protease self-immunity
HUT07_RS00035	COG0501	Belongs to the peptidase M48B family
HUT07_RS00105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HUT07_RS00115	COG4772	TonB-dependent receptor
HUT07_RS00150	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS00155	COG3284	Transcriptional regulator
HUT07_RS00160	COG0800	Aldolase
HUT07_RS00185	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT07_RS00200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUT07_RS00215	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT07_RS00220	COG1609	Transcriptional regulator
HUT07_RS00230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS00235	COG2755	lipolytic protein G-D-S-L family
HUT07_RS00245	COG3186	Phenylalanine-4-hydroxylase
HUT07_RS00250	COG1522	sequence-specific DNA binding
HUT07_RS00260	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUT07_RS00270	COG4771	TonB-dependent receptor
HUT07_RS00290	COG1122	ATPase activity
HUT07_RS00305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT07_RS00315	COG2815	serine threonine protein kinase
HUT07_RS00315	COG0515	serine threonine protein kinase
HUT07_RS00320	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HUT07_RS00330	COG1435	thymidine kinase activity
HUT07_RS00335	COG0210	DNA helicase
HUT07_RS00360	COG3132	Protein of unknown function, DUF480
HUT07_RS00365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HUT07_RS00370	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT07_RS00380	COG2937	Belongs to the GPAT DAPAT family
HUT07_RS00395	COG0037	tRNA processing
HUT07_RS00400	COG2974	May be involved in recombination
HUT07_RS00410	COG1803	Methylglyoxal synthase
HUT07_RS00415	COG2205	protein histidine kinase activity
HUT07_RS00415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT07_RS00420	COG0493	'glutamate synthase
HUT07_RS00425	COG0069	glutamate synthase activity
HUT07_RS00425	COG0070	glutamate synthase
HUT07_RS00425	COG0067	glutamate synthase
HUT07_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS00450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT07_RS00475	COG1111	helicase
HUT07_RS00475	COG1205	dead DEAH box helicase
HUT07_RS00515	COG0714	Associated with various cellular activities
HUT07_RS00535	COG0312	modulator of DNA gyrase
HUT07_RS00545	COG3550	peptidyl-serine autophosphorylation
HUT07_RS00565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT07_RS00585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT07_RS00625	COG1968	undecaprenyl-diphosphatase activity
HUT07_RS00630	COG0174	glutamine synthetase
HUT07_RS00635	COG0347	Belongs to the P(II) protein family
HUT07_RS00640	COG0004	ammonium transporteR
HUT07_RS00650	COG3279	Response regulator of the LytR AlgR family
HUT07_RS00665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HUT07_RS00690	COG3852	Histidine kinase
HUT07_RS00695	COG2204	response regulator
HUT07_RS00700	COG2032	superoxide dismutase activity
HUT07_RS00705	COG2032	superoxide dismutase activity
HUT07_RS00715	COG0183	Belongs to the thiolase family
HUT07_RS00750	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HUT07_RS00755	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT07_RS00780	COG2200	EAL domain
HUT07_RS00820	COG2837	iron assimilation
HUT07_RS00860	COG2197	response regulator
HUT07_RS00865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT07_RS00865	COG2205	protein histidine kinase activity
HUT07_RS00870	COG3474	cytochrome
HUT07_RS00880	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS00885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUT07_RS00895	COG0612	Peptidase, M16
HUT07_RS00905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT07_RS00910	COG0596	Alpha beta hydrolase
HUT07_RS00920	COG0318	PFAM AMP-dependent synthetase and ligase
HUT07_RS00925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT07_RS00935	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT07_RS00945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT07_RS00960	COG1215	transferase activity, transferring glycosyl groups
HUT07_RS00965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT07_RS00975	COG0564	pseudouridine synthase activity
HUT07_RS00995	COG0339	signal peptide processing
HUT07_RS01010	COG0681	Belongs to the peptidase S26 family
HUT07_RS01015	COG2814	Major facilitator Superfamily
HUT07_RS01020	COG0583	DNA-binding transcription factor activity
HUT07_RS01025	COG0583	DNA-binding transcription factor activity
HUT07_RS01030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUT07_RS01035	COG2224	Isocitrate lyase
HUT07_RS01065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT07_RS01070	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS01090	COG0697	spore germination
HUT07_RS01100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUT07_RS01110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT07_RS01115	COG1280	lysine exporter protein (LysE YggA)
HUT07_RS01120	COG1607	acyl-coa hydrolase
HUT07_RS01130	COG1902	pentaerythritol trinitrate reductase activity
HUT07_RS01145	COG1335	isochorismatase
HUT07_RS01150	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUT07_RS01155	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUT07_RS01165	COG1396	sequence-specific DNA binding
HUT07_RS01165	COG3800	Transcriptional regulator
HUT07_RS01175	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS01180	COG1024	Enoyl-CoA hydratase
HUT07_RS01185	COG1024	Enoyl-CoA hydratase
HUT07_RS01195	COG1764	response to oxidative stress
HUT07_RS01205	COG0659	secondary active sulfate transmembrane transporter activity
HUT07_RS01210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUT07_RS01220	COG0745	RESPONSE REGULATOR receiver
HUT07_RS01225	COG2205	protein histidine kinase activity
HUT07_RS01230	COG3228	Belongs to the MtfA family
HUT07_RS01240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HUT07_RS01240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HUT07_RS01245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT07_RS01295	COG3237	CsbD-like
HUT07_RS01305	COG0180	Tryptophanyl-tRNA synthetase
HUT07_RS01325	COG0477	Major facilitator Superfamily
HUT07_RS01330	COG0697	spore germination
HUT07_RS01345	COG0577	efflux transmembrane transporter activity
HUT07_RS01345	COG1136	(ABC) transporter
HUT07_RS01355	COG1136	(ABC) transporter
HUT07_RS01360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS01365	COG1131	(ABC) transporter
HUT07_RS01375	COG4585	Histidine kinase
HUT07_RS01380	COG2197	response regulator
HUT07_RS01385	COG3038	cytochrome b561
HUT07_RS01395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT07_RS01410	COG0628	permease
HUT07_RS01430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT07_RS01445	COG5507	3-demethylubiquinone-9 3-methyltransferase
HUT07_RS01470	COG2814	Major facilitator Superfamily
HUT07_RS01475	COG0583	DNA-binding transcription factor activity
HUT07_RS01480	COG4807	Protein conserved in bacteria
HUT07_RS01490	COG4221	oxidoreductase activity
HUT07_RS01500	COG0018	arginyl-trna synthetase
HUT07_RS01505	COG2003	Belongs to the UPF0758 family
HUT07_RS01510	COG2197	response regulator
HUT07_RS01515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUT07_RS01520	COG0756	dUTP diphosphatase activity
HUT07_RS01530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT07_RS01535	COG4232	protein-disulfide reductase activity
HUT07_RS01540	COG1324	tolerance protein
HUT07_RS01545	COG2356	endonuclease I
HUT07_RS01550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT07_RS01555	COG0459	protein refolding
HUT07_RS01560	COG0583	DNA-binding transcription factor activity
HUT07_RS01565	COG0625	glutathione transferase activity
HUT07_RS01575	COG1846	Transcriptional regulator
HUT07_RS01595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUT07_RS01600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS01615	COG2860	membrane
HUT07_RS01635	COG1252	NADH dehydrogenase
HUT07_RS01645	COG0625	glutathione transferase activity
HUT07_RS01650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUT07_RS01665	COG0534	Mate efflux family protein
HUT07_RS01670	COG0616	signal peptide processing
HUT07_RS01695	COG0009	L-threonylcarbamoyladenylate synthase
HUT07_RS01700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT07_RS01700	COG1754	DNA topoisomerase type I activity
HUT07_RS01705	COG1714	RDD family
HUT07_RS01715	COG2922	Belongs to the Smg family
HUT07_RS01720	COG0758	DNA mediated transformation
HUT07_RS01725	COG1652	LysM domain
HUT07_RS01730	COG0242	peptide deformylase activity
HUT07_RS01735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT07_RS01740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT07_RS01740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUT07_RS01745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT07_RS01785	COG1490	D-aminoacyl-tRNA deacylase activity
HUT07_RS01790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT07_RS01855	COG0745	RESPONSE REGULATOR receiver
HUT07_RS01860	COG2205	protein histidine kinase activity
HUT07_RS01865	COG0745	RESPONSE REGULATOR receiver
HUT07_RS01885	COG0745	RESPONSE REGULATOR receiver
HUT07_RS01895	COG0625	glutathione transferase activity
HUT07_RS01940	COG0583	DNA-binding transcription factor activity
HUT07_RS01955	COG0477	Major facilitator Superfamily
HUT07_RS01970	COG0840	transmembrane signaling receptor activity
HUT07_RS01985	COG4771	TonB-dependent receptor
HUT07_RS01995	COG0400	carboxylic ester hydrolase activity
HUT07_RS02000	COG3275	phosphorelay sensor kinase activity
HUT07_RS02010	COG0181	hydroxymethylbilane synthase activity
HUT07_RS02035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT07_RS02055	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT07_RS02060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT07_RS02075	COG0356	it plays a direct role in the translocation of protons across the membrane
HUT07_RS02085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT07_RS02090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT07_RS02095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT07_RS02100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT07_RS02105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT07_RS02110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT07_RS02120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT07_RS02130	COG4191	Histidine kinase
HUT07_RS02145	COG0577	efflux transmembrane transporter activity
HUT07_RS02145	COG1136	(ABC) transporter
HUT07_RS02150	COG0577	efflux transmembrane transporter activity
HUT07_RS02150	COG1136	(ABC) transporter
HUT07_RS02155	COG1136	(ABC) transporter
HUT07_RS02165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT07_RS02180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUT07_RS02180	COG0517	IMP dehydrogenase activity
HUT07_RS02195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT07_RS02205	COG0339	signal peptide processing
HUT07_RS02220	COG1666	GTP binding
HUT07_RS02225	COG0697	spore germination
HUT07_RS02230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT07_RS02235	COG2011	ABC-type metal ion transport system permease component
HUT07_RS02250	COG1505	serine-type exopeptidase activity
HUT07_RS02265	COG2832	Protein of unknown function (DUF454)
HUT07_RS02275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT07_RS02295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HUT07_RS02310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS02345	COG2226	methyltransferase
HUT07_RS02350	COG0308	aminopeptidase N
HUT07_RS02360	COG0546	phosphoglycolate phosphatase activity
HUT07_RS02365	COG1368	sulfuric ester hydrolase activity
HUT07_RS02370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT07_RS02375	COG1077	Cell shape determining protein MreB Mrl
HUT07_RS02380	COG1792	Involved in formation and maintenance of cell shape
HUT07_RS02395	COG0772	Belongs to the SEDS family
HUT07_RS02405	COG0772	Belongs to the SEDS family
HUT07_RS02410	COG2951	lytic endotransglycosylase activity
HUT07_RS02420	COG1686	Belongs to the peptidase S11 family
HUT07_RS02430	COG2921	Belongs to the UPF0250 family
HUT07_RS02440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT07_RS02460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT07_RS02465	COG0673	inositol 2-dehydrogenase activity
HUT07_RS02470	COG2823	Periplasmic or secreted lipoprotein
HUT07_RS02475	COG4251	negative regulation of phosphorylation
HUT07_RS02480	COG0784	Response regulator, receiver
HUT07_RS02495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUT07_RS02515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT07_RS02525	COG0837	glucose binding
HUT07_RS02535	COG1609	Transcriptional regulator
HUT07_RS02540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT07_RS02545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT07_RS02555	COG3468	outer membrane autotransporter barrel domain protein
HUT07_RS02590	COG0617	tRNA 3'-terminal CCA addition
HUT07_RS02605	COG4206	TonB-dependent receptor
HUT07_RS02610	COG4773	Receptor
HUT07_RS02620	COG1522	sequence-specific DNA binding
HUT07_RS02635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT07_RS02650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUT07_RS02655	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUT07_RS02675	COG1064	alcohol dehydrogenase
HUT07_RS02680	COG0583	DNA-binding transcription factor activity
HUT07_RS02695	COG1902	pentaerythritol trinitrate reductase activity
HUT07_RS02710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT07_RS02715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT07_RS02720	COG4251	negative regulation of phosphorylation
HUT07_RS02720	COG3706	GGDEF domain
HUT07_RS02720	COG2203	Gaf domain
HUT07_RS02720	COG5001	Diguanylate cyclase
HUT07_RS02760	COG1307	EDD domain protein, DegV family
HUT07_RS02770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT07_RS02775	COG1228	amidohydrolase
HUT07_RS02795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUT07_RS02800	COG0726	polysaccharide deacetylase
HUT07_RS02815	COG0436	Aminotransferase
HUT07_RS02820	COG1162	GTPase activity
HUT07_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS02840	COG2851	Citrate transporter
HUT07_RS02855	COG0642	Histidine kinase
HUT07_RS02870	COG4191	Histidine kinase
HUT07_RS02880	COG1301	dicarboxylic acid transport
HUT07_RS02920	COG1560	Kdo2-lipid A biosynthetic process
HUT07_RS02925	COG1519	Transferase
HUT07_RS02935	COG1538	Outer membrane efflux protein
HUT07_RS02940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT07_RS02955	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS02975	COG0473	3-isopropylmalate dehydrogenase activity
HUT07_RS02990	COG4106	trans-aconitate 2-methyltransferase activity
HUT07_RS02995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT07_RS03015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT07_RS03020	COG0405	Gamma-glutamyltransferase
HUT07_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT07_RS03030	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT07_RS03040	COG0745	RESPONSE REGULATOR receiver
HUT07_RS03050	COG4771	TonB-dependent receptor
HUT07_RS03060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT07_RS03095	COG2832	Protein of unknown function (DUF454)
HUT07_RS03105	COG0848	biopolymer transport protein
HUT07_RS03115	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT07_RS03135	COG0563	adenylate kinase activity
HUT07_RS03140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT07_RS03150	COG0671	phosphoesterase, PA-phosphatase related
HUT07_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS03175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT07_RS03180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT07_RS03195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT07_RS03205	COG1773	rubredoxin
HUT07_RS03210	COG2912	Transglutaminase-like superfamily
HUT07_RS03220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HUT07_RS03230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT07_RS03250	COG3079	Belongs to the UPF0149 family
HUT07_RS03255	COG0006	proline dipeptidase activity
HUT07_RS03260	COG0006	proline dipeptidase activity
HUT07_RS03275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT07_RS03285	COG0346	lactoylglutathione lyase activity
HUT07_RS03290	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT07_RS03295	COG1561	YicC-like family, N-terminal region
HUT07_RS03305	COG1758	RNA polymerase activity
HUT07_RS03310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT07_RS03320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUT07_RS03335	COG0254	rRNA binding
HUT07_RS03355	COG2267	carboxylic ester hydrolase activity
HUT07_RS03395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT07_RS03425	COG0714	Associated with various cellular activities
HUT07_RS03445	COG2304	oxidoreductase activity
HUT07_RS03455	COG1301	dicarboxylic acid transport
HUT07_RS03460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT07_RS03470	COG3093	addiction module antidote protein HigA
HUT07_RS03525	COG5001	Diguanylate cyclase
HUT07_RS03525	COG3300	MHYT domain
HUT07_RS03530	COG3047	cAMP biosynthetic process
HUT07_RS03535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT07_RS03550	COG0126	phosphoglycerate kinase activity
HUT07_RS03560	COG0469	pyruvate kinase activity
HUT07_RS03565	COG3588	fructose-bisphosphate aldolase
HUT07_RS03575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT07_RS03585	COG0583	DNA-binding transcription factor activity
HUT07_RS03605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS03610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT07_RS03615	COG1115	amino acid carrier protein
HUT07_RS03620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT07_RS03630	COG1970	mechanosensitive ion channel activity
HUT07_RS03650	COG3273	potassium ion transport
HUT07_RS03650	COG0471	metal ion transport
HUT07_RS03660	COG2022	thiamine diphosphate biosynthetic process
HUT07_RS03670	COG3240	lipase activity
HUT07_RS03670	COG4625	pathogenesis
HUT07_RS03685	COG0189	ligase activity
HUT07_RS03700	COG0745	RESPONSE REGULATOR receiver
HUT07_RS03720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HUT07_RS03750	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT07_RS03755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUT07_RS03760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT07_RS03760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT07_RS03765	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT07_RS03770	COG0564	pseudouridine synthase activity
HUT07_RS03790	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT07_RS03795	COG3387	PFAM Glycoside hydrolase 15-related
HUT07_RS03820	COG0028	Belongs to the TPP enzyme family
HUT07_RS03840	COG0542	response to heat
HUT07_RS03850	COG2205	protein histidine kinase activity
HUT07_RS03855	COG0745	RESPONSE REGULATOR receiver
HUT07_RS03870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT07_RS03870	COG4651	solute:proton antiporter activity
HUT07_RS03880	COG0488	(ABC) transporter
HUT07_RS03895	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HUT07_RS03910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT07_RS03930	COG0217	transcriptional regulatory protein
HUT07_RS03935	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT07_RS03940	COG0632	four-way junction helicase activity
HUT07_RS03950	COG2255	four-way junction helicase activity
HUT07_RS03955	COG0824	Thioesterase
HUT07_RS03975	COG0823	Involved in the tonB-independent uptake of proteins
HUT07_RS03980	COG2885	chlorophyll binding
HUT07_RS03990	COG0602	queuosine metabolic process
HUT07_RS03995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUT07_RS04010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT07_RS04060	COG2132	Multicopper oxidase
HUT07_RS04070	COG0514	ATP-dependent DNA helicase (RecQ)
HUT07_RS04075	COG0783	Belongs to the Dps family
HUT07_RS04080	COG1643	Atp-dependent helicase
HUT07_RS04090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT07_RS04100	COG1442	glycosyl transferase family 8
HUT07_RS04100	COG1216	Glycosyl transferase, family 2
HUT07_RS04105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT07_RS04115	COG1199	ATP-dependent helicase activity
HUT07_RS04130	COG0189	ligase activity
HUT07_RS04145	COG0835	chemotaxis
HUT07_RS04150	COG0840	transmembrane signaling receptor activity
HUT07_RS04155	COG2198	Histidine kinase
HUT07_RS04155	COG0784	Response regulator, receiver
HUT07_RS04155	COG0643	Histidine kinase
HUT07_RS04170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUT07_RS04180	COG0494	nUDIX hydrolase
HUT07_RS04185	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUT07_RS04190	COG3956	TIGRFAM MazG family protein
HUT07_RS04195	COG1742	UPF0060 membrane protein
HUT07_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS04215	COG2271	Major facilitator Superfamily
HUT07_RS04235	COG2186	Transcriptional regulator
HUT07_RS04240	COG0330	HflC and HflK could
HUT07_RS04250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT07_RS04255	COG0509	glycine decarboxylation via glycine cleavage system
HUT07_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS04300	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS04310	COG1309	transcriptional regulator
HUT07_RS04330	COG4206	TonB-dependent receptor
HUT07_RS04340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HUT07_RS04350	COG0463	Glycosyl transferase, family 2
HUT07_RS04360	COG2982	Protein involved in outer membrane biogenesis
HUT07_RS04365	COG1272	protein, Hemolysin III
HUT07_RS04370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUT07_RS04375	COG0739	heme binding
HUT07_RS04380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT07_RS04385	COG0626	cystathionine gamma-synthase activity
HUT07_RS04390	COG0460	homoserine dehydrogenase
HUT07_RS04390	COG0527	aspartate kinase activity
HUT07_RS04395	COG0596	Alpha beta hydrolase
HUT07_RS04400	COG1760	l-serine dehydratase
HUT07_RS04415	COG3038	cytochrome b561
HUT07_RS04425	COG5002	protein histidine kinase activity
HUT07_RS04425	COG2198	Histidine kinase
HUT07_RS04425	COG0784	Response regulator, receiver
HUT07_RS04430	COG2205	protein histidine kinase activity
HUT07_RS04430	COG2198	Histidine kinase
HUT07_RS04430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT07_RS04430	COG0784	Response regulator, receiver
HUT07_RS04435	COG0477	Major facilitator Superfamily
HUT07_RS04455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT07_RS04480	COG3829	transcription factor binding
HUT07_RS04500	COG3609	addiction module antidote protein, CC2985 family
HUT07_RS04510	COG2828	Protein conserved in bacteria
HUT07_RS04515	COG2079	MmgE PrpD family protein
HUT07_RS04520	COG2373	Large extracellular alpha-helical protein
HUT07_RS04525	COG4953	penicillin-binding protein 1C
HUT07_RS04535	COG0678	peroxiredoxin activity
HUT07_RS04550	COG0604	alcohol dehydrogenase
HUT07_RS04555	COG0330	HflC and HflK could
HUT07_RS04560	COG0330	HflC and HflK could
HUT07_RS04570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT07_RS04580	COG0739	heme binding
HUT07_RS04585	COG1376	ErfK ybiS ycfS ynhG family protein
HUT07_RS04590	COG0840	transmembrane signaling receptor activity
HUT07_RS04615	COG0753	catalase activity
HUT07_RS04620	COG1917	Cupin 2, conserved barrel domain protein
HUT07_RS04620	COG2207	Transcriptional regulator
HUT07_RS04625	COG1113	amino acid transport
HUT07_RS04635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT07_RS04635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT07_RS04640	COG2814	Major facilitator Superfamily
HUT07_RS04670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT07_RS04675	COG0745	RESPONSE REGULATOR receiver
HUT07_RS04680	COG2205	protein histidine kinase activity
HUT07_RS04700	COG2879	small protein
HUT07_RS04705	COG1966	Carbon starvation protein
HUT07_RS04710	COG1741	Belongs to the pirin family
HUT07_RS04720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT07_RS04725	COG1741	Belongs to the pirin family
HUT07_RS04735	COG1024	Enoyl-CoA hydratase
HUT07_RS04735	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT07_RS04750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT07_RS04755	COG0481	GTPase activity
HUT07_RS04760	COG0681	Belongs to the peptidase S26 family
HUT07_RS04775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT07_RS04780	COG1381	Involved in DNA repair and RecF pathway recombination
HUT07_RS04795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT07_RS04805	COG2954	triphosphatase activity
HUT07_RS04810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT07_RS04815	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT07_RS04825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT07_RS04830	COG1278	Cold shock
HUT07_RS04835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT07_RS04850	COG1201	RNA secondary structure unwinding
HUT07_RS04855	COG1793	dna ligase
HUT07_RS04865	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS04880	COG0183	Belongs to the thiolase family
HUT07_RS04900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT07_RS04910	COG1451	nucleotide metabolic process
HUT07_RS04915	COG3122	Protein conserved in bacteria
HUT07_RS04920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUT07_RS04960	COG0443	Heat shock 70 kDa protein
HUT07_RS04965	COG2824	Alkylphosphonate utilization operon protein PhnA
HUT07_RS04995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT07_RS04995	COG0392	lysyltransferase activity
HUT07_RS05000	COG0251	oxidation-reduction process
HUT07_RS05010	COG2878	Part of a membrane complex involved in electron transport
HUT07_RS05020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT07_RS05020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT07_RS05030	COG0346	lactoylglutathione lyase activity
HUT07_RS05035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT07_RS05045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUT07_RS05070	COG4251	negative regulation of phosphorylation
HUT07_RS05070	COG5001	Diguanylate cyclase
HUT07_RS05070	COG3706	GGDEF domain
HUT07_RS05070	COG2203	Gaf domain
HUT07_RS05080	COG3118	belongs to the thioredoxin family
HUT07_RS05090	COG0495	leucyl-tRNA aminoacylation
HUT07_RS05105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT07_RS05115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUT07_RS05125	COG2755	lipolytic protein G-D-S-L family
HUT07_RS05125	COG0657	acetylesterase activity
HUT07_RS05135	COG4771	TonB-dependent receptor
HUT07_RS05145	COG2968	Membrane
HUT07_RS05155	COG1530	ribonuclease E activity
HUT07_RS05165	COG0312	modulator of DNA gyrase
HUT07_RS05170	COG3028	Belongs to the UPF0307 family
HUT07_RS05175	COG0312	modulator of DNA gyrase
HUT07_RS05185	COG0142	geranyltranstransferase activity
HUT07_RS05190	COG1722	exodeoxyribonuclease VII activity
HUT07_RS05210	COG1301	dicarboxylic acid transport
HUT07_RS05250	COG0791	NLP P60 protein
HUT07_RS05255	COG0791	NLP P60 protein
HUT07_RS05260	COG1047	Peptidyl-prolyl cis-trans
HUT07_RS05265	COG2311	Membrane
HUT07_RS05275	COG0697	spore germination
HUT07_RS05310	COG3590	peptidase
HUT07_RS05315	COG4771	TonB-dependent receptor
HUT07_RS05320	COG4771	TonB-dependent receptor
HUT07_RS05330	COG4771	TonB-dependent receptor
HUT07_RS05335	COG4771	TonB-dependent receptor
HUT07_RS05340	COG0489	protein tyrosine kinase activity
HUT07_RS05345	COG0717	Belongs to the dCTP deaminase family
HUT07_RS05360	COG0412	Dienelactone hydrolase
HUT07_RS05365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT07_RS05375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT07_RS05380	COG0433	COG0433 Predicted ATPase
HUT07_RS05395	COG0688	phosphatidylethanolamine metabolic process
HUT07_RS05400	COG1999	signal sequence binding
HUT07_RS05405	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT07_RS05410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT07_RS05415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT07_RS05420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUT07_RS05435	COG0101	tRNA pseudouridine synthase activity
HUT07_RS05440	COG0135	phosphoribosylanthranilate isomerase activity
HUT07_RS05475	COG0133	tryptophan synthase activity
HUT07_RS05485	COG0159	tryptophan synthase activity
HUT07_RS05490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT07_RS05495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT07_RS05500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT07_RS05505	COG0726	polysaccharide deacetylase
HUT07_RS05510	COG0438	transferase activity, transferring glycosyl groups
HUT07_RS05525	COG0149	triose-phosphate isomerase activity
HUT07_RS05540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT07_RS05545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT07_RS05550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT07_RS05555	COG0649	NAD binding
HUT07_RS05560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HUT07_RS05565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT07_RS05575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT07_RS05580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT07_RS05590	COG0713	ATP synthesis coupled electron transport
HUT07_RS05605	COG1007	ATP synthesis coupled electron transport
HUT07_RS05620	COG0779	Required for maturation of 30S ribosomal subunits
HUT07_RS05625	COG0195	Participates in both transcription termination and antitermination
HUT07_RS05630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT07_RS05635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT07_RS05645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT07_RS05650	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT07_RS05680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT07_RS05685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT07_RS05695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT07_RS05700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT07_RS05710	COG0776	regulation of translation
HUT07_RS05750	COG1794	racemase activity, acting on amino acids and derivatives
HUT07_RS05760	COG1280	lysine exporter protein (LysE YggA)
HUT07_RS05770	COG2076	Multidrug Resistance protein
HUT07_RS05775	COG1309	transcriptional regulator
HUT07_RS05810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT07_RS05820	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS05845	COG2130	NADP-dependent
HUT07_RS05850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT07_RS05850	COG2169	Transcriptional regulator
HUT07_RS05885	COG1309	transcriptional regulator
HUT07_RS05910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT07_RS05920	COG1570	exodeoxyribonuclease VII activity
HUT07_RS05925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUT07_RS05930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUT07_RS05930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUT07_RS05935	COG0802	atpase or kinase
HUT07_RS05945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUT07_RS05965	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS05975	COG0501	Belongs to the peptidase M48B family
HUT07_RS05980	COG0483	inositol monophosphate 1-phosphatase activity
HUT07_RS05995	COG5001	Diguanylate cyclase
HUT07_RS05995	COG3300	MHYT domain
HUT07_RS06000	COG1509	lysine 2,3-aminomutase activity
HUT07_RS06005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT07_RS06010	COG0402	S-adenosylhomocysteine deaminase activity
HUT07_RS06015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT07_RS06035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT07_RS06055	COG2166	iron-sulfur cluster assembly
HUT07_RS06070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT07_RS06075	COG0137	argininosuccinate synthase activity
HUT07_RS06080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT07_RS06085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT07_RS06095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT07_RS06100	COG0165	Argininosuccinate lyase
HUT07_RS06115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT07_RS06130	COG1215	transferase activity, transferring glycosyl groups
HUT07_RS06135	COG1649	PFAM Uncharacterised BCR, COG1649
HUT07_RS06135	COG0726	polysaccharide deacetylase
HUT07_RS06165	COG1294	oxidase, subunit
HUT07_RS06170	COG1271	oxidase subunit
HUT07_RS06175	COG4988	ABC transporter
HUT07_RS06180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUT07_RS06190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT07_RS06200	COG3088	subunit of a heme lyase
HUT07_RS06200	COG4235	cytochrome complex assembly
HUT07_RS06215	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HUT07_RS06240	COG0436	Aminotransferase
HUT07_RS06260	COG1187	pseudouridine synthase activity
HUT07_RS06265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT07_RS06270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT07_RS06275	COG2350	Protein conserved in bacteria
HUT07_RS06280	COG0271	Belongs to the BolA IbaG family
HUT07_RS06310	COG0395	ABC-type sugar transport system, permease component
HUT07_RS06325	COG1530	ribonuclease E activity
HUT07_RS06335	COG0428	transporter
HUT07_RS06345	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT07_RS06350	COG0316	Belongs to the HesB IscA family
HUT07_RS06350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HUT07_RS06370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT07_RS06380	COG3104	oligopeptide transport
HUT07_RS06385	COG0705	Rhomboid family
HUT07_RS06405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT07_RS06410	COG0339	signal peptide processing
HUT07_RS06415	COG0386	Belongs to the glutathione peroxidase family
HUT07_RS06430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT07_RS06435	COG1595	DNA-templated transcription, initiation
HUT07_RS06465	COG2839	Protein conserved in bacteria
HUT07_RS06485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUT07_RS06490	COG0084	hydrolase, TatD family'
HUT07_RS06510	COG0625	glutathione transferase activity
HUT07_RS06530	COG0305	Participates in initiation and elongation during chromosome replication
HUT07_RS06535	COG4774	siderophore transport
HUT07_RS06540	COG3540	Alkaline phosphatase
HUT07_RS06570	COG0567	Dehydrogenase, E1 component
HUT07_RS06580	COG2850	peptidyl-arginine hydroxylation
HUT07_RS06620	COG1131	(ABC) transporter
HUT07_RS06625	COG1725	Transcriptional regulator
HUT07_RS06630	COG0386	Belongs to the glutathione peroxidase family
HUT07_RS06645	COG2900	Belongs to the SlyX family
HUT07_RS06655	COG2755	lipolytic protein G-D-S-L family
HUT07_RS06655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT07_RS06675	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS06680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS06685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS06695	COG2902	Dehydrogenase
HUT07_RS06720	COG2925	Exonuclease
HUT07_RS06725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT07_RS06730	COG3844	kynureninase activity
HUT07_RS06740	COG0288	reversible hydration of carbon dioxide
HUT07_RS06745	COG2808	Putative FMN-binding domain
HUT07_RS06760	COG0017	Asparaginyl-tRNA synthetase
HUT07_RS06765	COG0316	Belongs to the HesB IscA family
HUT07_RS06775	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT07_RS06780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT07_RS06785	COG0359	binds to the 23S rRNA
HUT07_RS06800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT07_RS06805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT07_RS06815	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HUT07_RS06825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT07_RS06835	COG4993	Dehydrogenase
HUT07_RS06920	COG0583	DNA-binding transcription factor activity
HUT07_RS06925	COG2957	Belongs to the agmatine deiminase family
HUT07_RS06980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT07_RS06995	COG1228	amidohydrolase
HUT07_RS07040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUT07_RS07045	COG1605	Chorismate mutase
HUT07_RS07045	COG0077	Prephenate dehydratase
HUT07_RS07050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT07_RS07065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT07_RS07075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT07_RS07080	COG0583	DNA-binding transcription factor activity
HUT07_RS07175	COG1136	(ABC) transporter
HUT07_RS07175	COG0577	efflux transmembrane transporter activity
HUT07_RS07180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS07205	COG4774	siderophore transport
HUT07_RS07235	COG2814	Major facilitator Superfamily
HUT07_RS07250	COG3505	Type IV secretory pathway VirD4
HUT07_RS07260	COG3736	Type IV secretory pathway, component VirB8
HUT07_RS07270	COG2948	multi-organism process
HUT07_RS07290	COG3702	type iv secretory pathway
HUT07_RS07395	COG1902	pentaerythritol trinitrate reductase activity
HUT07_RS07400	COG0668	transmembrane transport
HUT07_RS07410	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HUT07_RS07430	COG0534	Mate efflux family protein
HUT07_RS07450	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUT07_RS07475	COG2183	response to ionizing radiation
HUT07_RS07480	COG5001	Diguanylate cyclase
HUT07_RS07480	COG3447	MASE1 domain protein
HUT07_RS07480	COG5002	protein histidine kinase activity
HUT07_RS07555	COG0789	Transcriptional regulator
HUT07_RS07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT07_RS07580	COG0531	amino acid
HUT07_RS07585	COG1982	Orn Lys Arg decarboxylase major
HUT07_RS07610	COG1629	transport
HUT07_RS07610	COG4206	TonB-dependent receptor
HUT07_RS07620	COG1595	DNA-templated transcription, initiation
HUT07_RS07645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUT07_RS07660	COG0587	DNA-directed DNA polymerase activity
HUT07_RS07715	COG2814	Major facilitator Superfamily
HUT07_RS07735	COG2207	Transcriptional regulator
HUT07_RS07750	COG1285	pathogenesis
HUT07_RS07760	COG2186	Transcriptional regulator
HUT07_RS07765	COG1304	FMN binding
HUT07_RS07770	COG0277	FAD linked oxidase domain protein
HUT07_RS07810	COG3161	chorismate lyase activity
HUT07_RS07820	COG0583	DNA-binding transcription factor activity
HUT07_RS07830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT07_RS07845	COG2197	response regulator
HUT07_RS07850	COG3850	Histidine kinase
HUT07_RS07865	COG1335	isochorismatase
HUT07_RS07875	COG1228	amidohydrolase
HUT07_RS07885	COG2814	Major facilitator Superfamily
HUT07_RS07940	COG4964	Belongs to the GSP D family
HUT07_RS07970	COG5295	Hep Hag repeat protein
HUT07_RS07975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUT07_RS07975	COG2885	chlorophyll binding
HUT07_RS08005	COG4772	TonB-dependent receptor
HUT07_RS08050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT07_RS08055	COG4206	TonB-dependent receptor
HUT07_RS08065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT07_RS08070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT07_RS08085	COG1914	H( )-stimulated, divalent metal cation uptake system
HUT07_RS08145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT07_RS08150	COG2409	Drug exporters of the RND superfamily
HUT07_RS08165	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT07_RS08170	COG3433	isochorismatase activity
HUT07_RS08170	COG1535	isochorismatase
HUT07_RS08180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT07_RS08180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT07_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS08205	COG2885	chlorophyll binding
HUT07_RS08240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT07_RS08245	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT07_RS08245	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT07_RS08250	COG0303	'Molybdopterin
HUT07_RS08260	COG0314	molybdopterin synthase activity
HUT07_RS08265	COG0746	molybdenum cofactor guanylyltransferase activity
HUT07_RS08275	COG2223	nitrite transmembrane transporter activity
HUT07_RS08280	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUT07_RS08285	COG1140	nitrate reductase beta subunit
HUT07_RS08290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUT07_RS08295	COG2181	nitrate reductase activity
HUT07_RS08300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUT07_RS08315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT07_RS08320	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUT07_RS08325	COG4149	molybdate abc transporter
HUT07_RS08330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUT07_RS08335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUT07_RS08340	COG0840	transmembrane signaling receptor activity
HUT07_RS08465	COG0811	peptide transport
HUT07_RS08495	COG1335	isochorismatase
HUT07_RS08500	COG1335	isochorismatase
HUT07_RS08510	COG0583	DNA-binding transcription factor activity
HUT07_RS08560	COG0477	Major facilitator Superfamily
HUT07_RS08570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT07_RS08585	COG3537	Alpha-1,2-mannosidase
HUT07_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS08605	COG4771	TonB-dependent receptor
HUT07_RS08645	COG0477	Major facilitator Superfamily
HUT07_RS08670	COG0243	molybdopterin cofactor binding
HUT07_RS08725	COG2205	protein histidine kinase activity
HUT07_RS08725	COG0784	Response regulator, receiver
HUT07_RS08730	COG2197	response regulator
HUT07_RS08735	COG2197	response regulator
HUT07_RS08750	COG3121	Chaperone
HUT07_RS08755	COG3188	usher protein
HUT07_RS08780	COG5295	Hep Hag repeat protein
HUT07_RS08785	COG5295	Hep Hag repeat protein
HUT07_RS08795	COG4566	intracellular signal transduction
HUT07_RS08800	COG4191	Histidine kinase
HUT07_RS08805	COG1285	pathogenesis
HUT07_RS08810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT07_RS08860	COG3214	Protein conserved in bacteria
HUT07_RS08925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT07_RS08995	COG0346	lactoylglutathione lyase activity
HUT07_RS09075	COG0318	PFAM AMP-dependent synthetase and ligase
HUT07_RS09090	COG2205	protein histidine kinase activity
HUT07_RS09100	COG0596	Alpha beta hydrolase
HUT07_RS09110	COG2610	gluconate transmembrane transporter activity
HUT07_RS09130	COG0431	NADPH-dependent FMN reductase
HUT07_RS09135	COG0583	DNA-binding transcription factor activity
HUT07_RS09140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUT07_RS09150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT07_RS09160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT07_RS09180	COG1073	alpha beta
HUT07_RS09195	COG0667	Aldo Keto reductase
HUT07_RS09210	COG4251	negative regulation of phosphorylation
HUT07_RS09210	COG5001	Diguanylate cyclase
HUT07_RS09210	COG2203	Gaf domain
HUT07_RS09210	COG3706	GGDEF domain
HUT07_RS09245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT07_RS09245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT07_RS09310	COG1725	Transcriptional regulator
HUT07_RS09325	COG5002	protein histidine kinase activity
HUT07_RS09325	COG0784	Response regulator, receiver
HUT07_RS09340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT07_RS09360	COG1120	ATPase activity
HUT07_RS09365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT07_RS09370	COG4558	Periplasmic binding protein
HUT07_RS09380	COG2819	hydrolase of the alpha beta superfamily
HUT07_RS09405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUT07_RS09425	COG1674	ftsk spoiiie
HUT07_RS09430	COG0492	ferredoxin-NADP+ reductase activity
HUT07_RS09460	COG0542	response to heat
HUT07_RS09470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT07_RS09485	COG0482	sulfurtransferase activity
HUT07_RS09490	COG2915	High frequency lysogenization protein hflD homolog
HUT07_RS09515	COG3851	Histidine kinase
HUT07_RS09525	COG5002	protein histidine kinase activity
HUT07_RS09545	COG0835	chemotaxis
HUT07_RS09545	COG0784	Response regulator, receiver
HUT07_RS09550	COG1815	bacterial-type flagellum-dependent cell motility
HUT07_RS09555	COG1558	bacterial-type flagellum-dependent cell motility
HUT07_RS09560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HUT07_RS09570	COG4787	bacterial-type flagellum-dependent cell motility
HUT07_RS09580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HUT07_RS09600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUT07_RS09610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUT07_RS09615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUT07_RS09620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HUT07_RS09640	COG2197	response regulator
HUT07_RS09665	COG1677	Flagellar hook-basal body complex protein FliE
HUT07_RS09715	COG3190	flagellar
HUT07_RS09725	COG1987	bacterial-type flagellum assembly
HUT07_RS09740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUT07_RS09745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUT07_RS09770	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HUT07_RS09775	COG2198	Histidine kinase
HUT07_RS09775	COG0784	Response regulator, receiver
HUT07_RS09775	COG0643	Histidine kinase
HUT07_RS09780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUT07_RS09785	COG1360	Flagellar Motor Protein
HUT07_RS09795	COG0835	chemotaxis
HUT07_RS09805	COG0745	RESPONSE REGULATOR receiver
HUT07_RS09815	COG0840	transmembrane signaling receptor activity
HUT07_RS09820	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HUT07_RS09825	COG0835	chemotaxis
HUT07_RS09835	COG0840	transmembrane signaling receptor activity
HUT07_RS09850	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HUT07_RS09900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT07_RS09905	COG1309	transcriptional regulator
HUT07_RS09910	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS09915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT07_RS09920	COG0318	PFAM AMP-dependent synthetase and ligase
HUT07_RS09925	COG1024	Enoyl-CoA hydratase
HUT07_RS09930	COG2198	Histidine kinase
HUT07_RS09930	COG0784	Response regulator, receiver
HUT07_RS09930	COG2205	protein histidine kinase activity
HUT07_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS09965	COG3279	Response regulator of the LytR AlgR family
HUT07_RS09985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUT07_RS10000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT07_RS10005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT07_RS10015	COG0505	Belongs to the CarA family
HUT07_RS10020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT07_RS10030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HUT07_RS10030	COG1918	ferrous iron import across plasma membrane
HUT07_RS10040	COG1024	Enoyl-CoA hydratase
HUT07_RS10065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT07_RS10085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS10090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS10095	COG0745	RESPONSE REGULATOR receiver
HUT07_RS10115	COG0277	FAD linked oxidase domain protein
HUT07_RS10120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT07_RS10130	COG0531	amino acid
HUT07_RS10135	COG0531	amino acid
HUT07_RS10155	COG0235	Class ii aldolase
HUT07_RS10160	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HUT07_RS10165	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HUT07_RS10180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT07_RS10190	COG1609	Transcriptional regulator
HUT07_RS10195	COG3537	Alpha-1,2-mannosidase
HUT07_RS10210	COG0789	Transcriptional regulator
HUT07_RS10225	COG3142	Participates in the control of copper homeostasis
HUT07_RS10230	COG1446	asparaginase
HUT07_RS10235	COG0837	glucose binding
HUT07_RS10250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT07_RS10250	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT07_RS10255	COG0107	imidazoleglycerol-phosphate synthase activity
HUT07_RS10260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT07_RS10270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT07_RS10270	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT07_RS10275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT07_RS10280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT07_RS10285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT07_RS10300	COG0124	histidyl-tRNA synthetase
HUT07_RS10305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT07_RS10310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT07_RS10320	COG0527	aspartate kinase activity
HUT07_RS10320	COG0460	homoserine dehydrogenase
HUT07_RS10360	COG0640	Transcriptional regulator
HUT07_RS10370	COG2205	protein histidine kinase activity
HUT07_RS10370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT07_RS10380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUT07_RS10385	COG3437	response regulator, receiver
HUT07_RS10385	COG4999	Histidine kinase
HUT07_RS10385	COG3850	Histidine kinase
HUT07_RS10385	COG2205	protein histidine kinase activity
HUT07_RS10390	COG0784	Response regulator, receiver
HUT07_RS10390	COG4191	Histidine kinase
HUT07_RS10550	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS10570	COG0167	dihydroorotate dehydrogenase activity
HUT07_RS10575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT07_RS10580	COG0697	spore germination
HUT07_RS10595	COG1309	transcriptional regulator
HUT07_RS10610	COG2199	diguanylate cyclase activity
HUT07_RS10610	COG2200	EAL domain
HUT07_RS10610	COG2203	Gaf domain
HUT07_RS10675	COG1473	amidohydrolase
HUT07_RS10680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT07_RS10685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT07_RS10740	COG0640	Transcriptional regulator
HUT07_RS10760	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS10775	COG0583	DNA-binding transcription factor activity
HUT07_RS10785	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HUT07_RS10805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT07_RS10805	COG0519	Catalyzes the synthesis of GMP from XMP
HUT07_RS10820	COG0475	glutathione-regulated potassium exporter activity
HUT07_RS10820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT07_RS10825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUT07_RS10835	COG1160	GTP binding
HUT07_RS10840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT07_RS10845	COG2976	Protein conserved in bacteria
HUT07_RS10850	COG1426	Protein conserved in bacteria
HUT07_RS10860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT07_RS10865	COG0105	UTP biosynthetic process
HUT07_RS10875	COG1024	Enoyl-CoA hydratase
HUT07_RS10875	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT07_RS10880	COG0183	Belongs to the thiolase family
HUT07_RS10895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT07_RS10900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HUT07_RS10910	COG0776	regulation of translation
HUT07_RS10920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT07_RS10925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT07_RS10935	COG2957	Belongs to the agmatine deiminase family
HUT07_RS10940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT07_RS10955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS10985	COG0583	DNA-binding transcription factor activity
HUT07_RS11005	COG0513	Belongs to the DEAD box helicase family
HUT07_RS11010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT07_RS11015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUT07_RS11035	COG0564	pseudouridine synthase activity
HUT07_RS11045	COG2081	HI0933 family
HUT07_RS11055	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT07_RS11060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT07_RS11065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT07_RS11070	COG1862	Preprotein translocase
HUT07_RS11075	COG0343	queuine tRNA-ribosyltransferase activity
HUT07_RS11080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT07_RS11085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT07_RS11095	COG4251	negative regulation of phosphorylation
HUT07_RS11095	COG5001	Diguanylate cyclase
HUT07_RS11095	COG3706	GGDEF domain
HUT07_RS11095	COG2203	Gaf domain
HUT07_RS11115	COG1132	(ABC) transporter
HUT07_RS11125	COG0287	Prephenate dehydrogenase
HUT07_RS11125	COG1605	Chorismate mutase
HUT07_RS11130	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUT07_RS11135	COG2223	nitrite transmembrane transporter activity
HUT07_RS11140	COG2207	Transcriptional regulator
HUT07_RS11145	COG0484	heat shock protein binding
HUT07_RS11150	COG0443	Heat shock 70 kDa protein
HUT07_RS11155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT07_RS11160	COG1420	regulation of RNA biosynthetic process
HUT07_RS11165	COG0497	DNA recombination
HUT07_RS11170	COG0583	DNA-binding transcription factor activity
HUT07_RS11180	COG0735	belongs to the Fur family
HUT07_RS11185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT07_RS11190	COG2914	Belongs to the UPF0125 (RnfH) family
HUT07_RS11200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT07_RS11305	COG0583	DNA-binding transcription factor activity
HUT07_RS11315	COG4221	oxidoreductase activity
HUT07_RS11320	COG2885	chlorophyll binding
HUT07_RS11325	COG0415	Belongs to the DNA photolyase family
HUT07_RS11355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT07_RS11365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT07_RS11370	COG0405	Gamma-glutamyltransferase
HUT07_RS11375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUT07_RS11385	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT07_RS11390	COG0742	ribosomal rna small subunit methyltransferase
HUT07_RS11405	COG0552	protein localization to endoplasmic reticulum
HUT07_RS11415	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HUT07_RS11430	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT07_RS11450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUT07_RS11455	COG2009	succinate dehydrogenase
HUT07_RS11465	COG0354	folic acid binding
HUT07_RS11475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUT07_RS11480	COG0837	glucose binding
HUT07_RS11490	COG0129	dihydroxy-acid dehydratase activity
HUT07_RS11495	COG0800	Aldolase
HUT07_RS11505	COG0671	phosphoesterase, PA-phosphatase related
HUT07_RS11510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT07_RS11520	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HUT07_RS11525	COG0166	Belongs to the GPI family
HUT07_RS11530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT07_RS11535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT07_RS11540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT07_RS11550	COG0617	tRNA 3'-terminal CCA addition
HUT07_RS11560	COG0477	Major facilitator Superfamily
HUT07_RS11565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUT07_RS11575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT07_RS11585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUT07_RS11590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT07_RS11605	COG0352	thiamine-phosphate diphosphorylase activity
HUT07_RS11605	COG0351	phosphomethylpyrimidine kinase
HUT07_RS11630	COG0583	DNA-binding transcription factor activity
HUT07_RS11635	COG1741	Belongs to the pirin family
HUT07_RS11650	COG2223	nitrite transmembrane transporter activity
HUT07_RS11665	COG3258	Cytochrome c
HUT07_RS11680	COG3540	Alkaline phosphatase
HUT07_RS11695	COG1595	DNA-templated transcription, initiation
HUT07_RS11700	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT07_RS11720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HUT07_RS11725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT07_RS11730	COG2137	regulation of response to DNA damage stimulus
HUT07_RS11735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT07_RS11740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT07_RS11745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT07_RS11750	COG1546	Belongs to the CinA family
HUT07_RS11755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT07_RS11760	COG1923	regulation of RNA biosynthetic process
HUT07_RS11765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT07_RS11770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT07_RS11780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT07_RS11785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HUT07_RS11790	COG1534	Rna-binding protein
HUT07_RS11810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT07_RS11815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUT07_RS11820	COG2840	Smr protein MutS2
HUT07_RS11830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT07_RS11835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT07_RS11840	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HUT07_RS11845	COG0148	phosphopyruvate hydratase activity
HUT07_RS11860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUT07_RS11865	COG0504	CTP synthase activity
HUT07_RS11880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT07_RS11900	COG1253	flavin adenine dinucleotide binding
HUT07_RS11915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT07_RS11945	COG0069	glutamate synthase activity
HUT07_RS11950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUT07_RS11975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT07_RS11990	COG0348	domain, Protein
HUT07_RS12005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT07_RS12010	COG4977	sequence-specific DNA binding
HUT07_RS12010	COG1917	Cupin 2, conserved barrel domain protein
HUT07_RS12035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT07_RS12075	COG1136	(ABC) transporter
HUT07_RS12075	COG0577	efflux transmembrane transporter activity
HUT07_RS12115	COG0322	excinuclease ABC activity
HUT07_RS12125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT07_RS12130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUT07_RS12135	COG1663	tetraacyldisaccharide 4'-kinase activity
HUT07_RS12150	COG0811	peptide transport
HUT07_RS12155	COG2333	competence protein COMEC
HUT07_RS12155	COG0658	competence protein
HUT07_RS12160	COG2205	protein histidine kinase activity
HUT07_RS12170	COG3713	MltA-interacting MipA family protein
HUT07_RS12220	COG0556	nucleotide-excision repair
HUT07_RS12265	COG1611	Belongs to the LOG family
HUT07_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS12280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUT07_RS12285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT07_RS12320	COG2969	positive regulation of protein catabolic process
HUT07_RS12325	COG0625	glutathione transferase activity
HUT07_RS12330	COG2857	Cytochrome c1
HUT07_RS12335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT07_RS12340	COG0723	plastoquinol--plastocyanin reductase activity
HUT07_RS12345	COG0741	lytic transglycosylase activity
HUT07_RS12360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT07_RS12365	COG0842	Transport permease protein
HUT07_RS12370	COG1131	(ABC) transporter
HUT07_RS12380	COG1702	phosphate starvation-inducible protein PhoH
HUT07_RS12390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT07_RS12405	COG4535	Mg2 and Co2 transporter CorC
HUT07_RS12420	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS12425	COG1177	transmembrane transport
HUT07_RS12430	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT07_RS12435	COG3842	ATPase activity
HUT07_RS12440	COG2072	flavoprotein involved in K transport
HUT07_RS12450	COG0174	glutamine synthetase
HUT07_RS12455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT07_RS12460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT07_RS12480	COG2703	oxygen carrier activity
HUT07_RS12485	COG0477	Major facilitator Superfamily
HUT07_RS12495	COG1012	belongs to the aldehyde dehydrogenase family
HUT07_RS12510	COG2733	membrane
HUT07_RS12535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUT07_RS12535	COG0116	Belongs to the methyltransferase superfamily
HUT07_RS12565	COG1024	Enoyl-CoA hydratase
HUT07_RS12575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUT07_RS12590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT07_RS12595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT07_RS12600	COG0573	inorganic phosphate transmembrane transporter activity
HUT07_RS12605	COG0581	inorganic phosphate transmembrane transporter activity
HUT07_RS12615	COG0704	Plays a role in the regulation of phosphate uptake
HUT07_RS12625	COG3220	belongs to the UPF0276 family
HUT07_RS12635	COG2259	Doxx family
HUT07_RS12640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUT07_RS12645	COG3706	GGDEF domain
HUT07_RS12655	COG0745	RESPONSE REGULATOR receiver
HUT07_RS12660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS12665	COG1136	(ABC) transporter
HUT07_RS12665	COG0577	efflux transmembrane transporter activity
HUT07_RS12670	COG1538	Outer membrane efflux protein
HUT07_RS12675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT07_RS12685	COG0557	exoribonuclease II activity
HUT07_RS12705	COG0583	DNA-binding transcription factor activity
HUT07_RS12730	COG2814	Major facilitator Superfamily
HUT07_RS12735	COG1566	PFAM secretion protein HlyD family protein
HUT07_RS12770	COG0475	glutathione-regulated potassium exporter activity
HUT07_RS12775	COG0367	asparagine synthase
HUT07_RS12785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT07_RS12790	COG1393	Belongs to the ArsC family
HUT07_RS12800	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT07_RS12820	COG3188	usher protein
HUT07_RS12840	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT07_RS12845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT07_RS12850	COG3706	GGDEF domain
HUT07_RS12855	COG0528	UMP kinase activity
HUT07_RS12860	COG0233	cytoplasmic translational termination
HUT07_RS12865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT07_RS12870	COG0575	Belongs to the CDS family
HUT07_RS12875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT07_RS12880	COG0750	zinc metalloprotease
HUT07_RS12890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT07_RS12895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT07_RS12900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT07_RS12925	COG0825	malonyl-CoA metabolic process
HUT07_RS13015	COG1132	(ABC) transporter
HUT07_RS13045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT07_RS13050	COG3706	GGDEF domain
HUT07_RS13055	COG1187	pseudouridine synthase activity
HUT07_RS13065	COG5001	Diguanylate cyclase
HUT07_RS13065	COG5002	protein histidine kinase activity
HUT07_RS13150	COG0735	belongs to the Fur family
HUT07_RS13155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT07_RS13170	COG4452	Inner membrane protein CreD
HUT07_RS13175	COG2205	protein histidine kinase activity
HUT07_RS13180	COG0745	RESPONSE REGULATOR receiver
HUT07_RS13185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUT07_RS13195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUT07_RS13215	COG3590	peptidase
HUT07_RS13220	COG0588	phosphoglycerate mutase activity
HUT07_RS13240	COG3706	GGDEF domain
HUT07_RS13245	COG2814	Major facilitator Superfamily
HUT07_RS13270	COG1647	Serine aminopeptidase, S33
HUT07_RS13295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT07_RS13320	COG0024	Methionine aminopeptidase
HUT07_RS13340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS13365	COG0840	transmembrane signaling receptor activity
HUT07_RS13380	COG2831	hemolysin activation secretion protein
HUT07_RS13400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT07_RS13420	COG0534	Mate efflux family protein
HUT07_RS13440	COG0335	large ribosomal subunit rRNA binding
HUT07_RS13445	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT07_RS13450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT07_RS13455	COG0228	four-way junction DNA binding
HUT07_RS13475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUT07_RS13500	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUT07_RS13505	COG1845	cytochrome c oxidase, subunit III
HUT07_RS13510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT07_RS13545	COG4245	von Willebrand factor, type A
HUT07_RS13555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT07_RS13575	COG4206	TonB-dependent receptor
HUT07_RS13600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT07_RS13610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT07_RS13615	COG0196	riboflavin kinase activity
HUT07_RS13620	COG0728	peptidoglycan biosynthetic process
HUT07_RS13625	COG0268	Binds directly to 16S ribosomal RNA
HUT07_RS13630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT07_RS13635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT07_RS13640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT07_RS13645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT07_RS13650	COG0824	Thioesterase
HUT07_RS13670	COG1946	Acyl-CoA thioesterase
HUT07_RS13680	COG1595	DNA-templated transcription, initiation
HUT07_RS13690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HUT07_RS13700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUT07_RS13720	COG1073	alpha beta
HUT07_RS13745	COG2197	response regulator
HUT07_RS13750	COG4585	Histidine kinase
HUT07_RS13765	COG2894	cell division
HUT07_RS13770	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HUT07_RS13785	COG1506	peptidase
HUT07_RS13785	COG0823	Involved in the tonB-independent uptake of proteins
HUT07_RS13790	COG1297	OPT oligopeptide transporter protein
HUT07_RS13800	COG3104	oligopeptide transport
HUT07_RS13840	COG0579	oxidoreductase
HUT07_RS13855	COG3052	prosthetic group binding
HUT07_RS13890	COG1802	Transcriptional regulator
HUT07_RS13905	COG0477	Major facilitator Superfamily
HUT07_RS13920	COG0745	RESPONSE REGULATOR receiver
HUT07_RS13935	COG2259	Doxx family
HUT07_RS13955	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HUT07_RS13965	COG1408	metallophosphoesterase
HUT07_RS13970	COG1253	flavin adenine dinucleotide binding
HUT07_RS13975	COG3655	Transcriptional regulator
HUT07_RS13990	COG0640	Transcriptional regulator
HUT07_RS14015	COG2199	diguanylate cyclase activity
HUT07_RS14015	COG2203	Gaf domain
HUT07_RS14035	COG0431	NADPH-dependent FMN reductase
HUT07_RS14045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT07_RS14050	COG0798	PFAM Bile acid sodium symporter
HUT07_RS14055	COG2259	Doxx family
HUT07_RS14060	COG1609	Transcriptional regulator
HUT07_RS14070	COG2211	Major facilitator Superfamily
HUT07_RS14075	COG0673	inositol 2-dehydrogenase activity
HUT07_RS14085	COG2010	Cytochrome c
HUT07_RS14120	COG0629	single-stranded DNA binding
HUT07_RS14135	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HUT07_RS14145	COG1131	(ABC) transporter
HUT07_RS14175	COG2190	(PTS) system
HUT07_RS14175	COG2211	Major facilitator Superfamily
HUT07_RS14185	COG1082	Xylose isomerase domain protein TIM barrel
HUT07_RS14195	COG0366	Alpha amylase catalytic
HUT07_RS14200	COG0142	geranyltranstransferase activity
HUT07_RS14220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT07_RS14230	COG0527	aspartate kinase activity
HUT07_RS14235	COG0384	phenazine biosynthesis protein PhzF
HUT07_RS14240	COG0384	phenazine biosynthesis protein PhzF
HUT07_RS14245	COG1764	response to oxidative stress
HUT07_RS14275	COG1959	2 iron, 2 sulfur cluster binding
HUT07_RS14280	COG0719	Fe-S assembly protein
HUT07_RS14285	COG3755	Protein conserved in bacteria
HUT07_RS14290	COG0396	ATPase activity
HUT07_RS14295	COG0719	Fe-S assembly protein
HUT07_RS14300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT07_RS14330	COG2146	nitrite reductase [NAD(P)H] activity
HUT07_RS14340	COG4774	siderophore transport
HUT07_RS14350	COG3128	pkhd-type hydroxylase
HUT07_RS14360	COG4771	TonB-dependent receptor
HUT07_RS14380	COG1477	protein flavinylation
HUT07_RS14385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUT07_RS14415	COG2261	transglycosylase associated protein
HUT07_RS14425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT07_RS14435	COG0628	permease
HUT07_RS14445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT07_RS14465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUT07_RS14485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT07_RS14500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUT07_RS14515	COG1137	ATPase activity
HUT07_RS14525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT07_RS14530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT07_RS14535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HUT07_RS14540	COG1660	Displays ATPase and GTPase activities
HUT07_RS14555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT07_RS14560	COG2239	Acts as a magnesium transporter
HUT07_RS14580	COG0540	Belongs to the ATCase OTCase family
HUT07_RS14585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT07_RS14590	COG1678	Uncharacterized ACR, COG1678
HUT07_RS14595	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUT07_RS14600	COG2818	Glycosylase
HUT07_RS14620	COG0667	Aldo Keto reductase
HUT07_RS14645	COG0583	DNA-binding transcription factor activity
HUT07_RS14695	COG2205	protein histidine kinase activity
HUT07_RS14705	COG0583	DNA-binding transcription factor activity
HUT07_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS14715	COG0697	spore germination
HUT07_RS14720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT07_RS14745	COG2223	nitrite transmembrane transporter activity
HUT07_RS14755	COG4774	siderophore transport
HUT07_RS14805	COG1388	LysM domain
HUT07_RS14910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT07_RS14915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUT07_RS14920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT07_RS14925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT07_RS14940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT07_RS14950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT07_RS14955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT07_RS14960	COG1399	metal-binding, possibly nucleic acid-binding protein
HUT07_RS14975	COG0714	Associated with various cellular activities
HUT07_RS14995	COG0537	adenosine 5'-monophosphoramidase activity
HUT07_RS15005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT07_RS15010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT07_RS15035	COG2076	Multidrug Resistance protein
HUT07_RS15050	COG1234	tRNA 3'-trailer cleavage
HUT07_RS15055	COG3642	lipopolysaccharide core region biosynthetic process
HUT07_RS15060	COG0859	PFAM glycosyl transferase family 9
HUT07_RS15075	COG0631	protein serine/threonine phosphatase activity
HUT07_RS15080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUT07_RS15095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT07_RS15100	COG1388	LysM domain
HUT07_RS15100	COG3942	CHAP domain
HUT07_RS15105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUT07_RS15140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT07_RS15150	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT07_RS15220	COG0473	3-isopropylmalate dehydrogenase activity
HUT07_RS15235	COG4783	chaperone-mediated protein folding
HUT07_RS15250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUT07_RS15255	COG0248	Ppx GppA phosphatase
HUT07_RS15260	COG4206	TonB-dependent receptor
HUT07_RS15265	COG0438	transferase activity, transferring glycosyl groups
HUT07_RS15270	COG0671	phosphoesterase, PA-phosphatase related
HUT07_RS15275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT07_RS15280	COG3291	Pkd domain containing protein
HUT07_RS15290	COG2833	Protein of unknown function (DUF455)
HUT07_RS15310	COG0285	dihydrofolate synthase activity
HUT07_RS15315	COG0406	alpha-ribazole phosphatase activity
HUT07_RS15325	COG1063	alcohol dehydrogenase
HUT07_RS15345	COG1187	pseudouridine synthase activity
HUT07_RS15360	COG0604	alcohol dehydrogenase
HUT07_RS15365	COG2364	Membrane
HUT07_RS15370	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT07_RS15370	COG1902	pentaerythritol trinitrate reductase activity
HUT07_RS15380	COG0625	glutathione transferase activity
HUT07_RS15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT07_RS15405	COG0039	L-malate dehydrogenase activity
HUT07_RS15410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT07_RS15425	COG0154	amidase activity
HUT07_RS15435	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT07_RS15450	COG0203	ribosomal protein L17
HUT07_RS15455	COG0202	RNA polymerase activity
HUT07_RS15460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT07_RS15465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT07_RS15470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT07_RS15475	COG0201	protein transport
HUT07_RS15485	COG1841	ribosomal large subunit assembly
HUT07_RS15490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT07_RS15495	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT07_RS15500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT07_RS15505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT07_RS15510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT07_RS15515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT07_RS15520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT07_RS15525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT07_RS15530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT07_RS15535	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT07_RS15540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT07_RS15545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT07_RS15550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT07_RS15555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT07_RS15560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT07_RS15565	COG0089	rRNA binding
HUT07_RS15570	COG0088	Forms part of the polypeptide exit tunnel
HUT07_RS15575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT07_RS15580	COG0051	transcription antitermination factor activity, RNA binding
HUT07_RS15585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT07_RS15590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT07_RS15605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT07_RS15610	COG0085	RNA polymerase activity
HUT07_RS15615	COG0222	ribosome binding
HUT07_RS15620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT07_RS15625	COG0081	regulation of translation
HUT07_RS15630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT07_RS15635	COG0250	Participates in transcription elongation, termination and antitermination
HUT07_RS15650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT07_RS15670	COG1446	asparaginase
HUT07_RS15675	COG4242	Belongs to the peptidase S51 family
HUT07_RS15680	COG4206	TonB-dependent receptor
HUT07_RS15685	COG2205	protein histidine kinase activity
HUT07_RS15685	COG0784	Response regulator, receiver
HUT07_RS15690	COG2199	diguanylate cyclase activity
HUT07_RS15690	COG2200	EAL domain
HUT07_RS15690	COG2203	Gaf domain
HUT07_RS15695	COG2205	protein histidine kinase activity
HUT07_RS15695	COG0784	Response regulator, receiver
HUT07_RS15700	COG2197	response regulator
HUT07_RS15715	COG0012	GTP binding
HUT07_RS15720	COG0193	aminoacyl-tRNA hydrolase activity
HUT07_RS15730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT07_RS15740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT07_RS15755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT07_RS15760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT07_RS15775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT07_RS15780	COG1295	ribonuclease BN
HUT07_RS15800	COG1404	Belongs to the peptidase S8 family
HUT07_RS15805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT07_RS15820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUT07_RS15845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT07_RS15885	COG0583	DNA-binding transcription factor activity
HUT07_RS15895	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT07_RS15905	COG3634	alkyl hydroperoxide reductase activity
HUT07_RS15910	COG0583	DNA-binding transcription factor activity
HUT07_RS15915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT07_RS15925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT07_RS15935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT07_RS15950	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HUT07_RS15955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT07_RS15960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT07_RS15965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT07_RS15975	COG2096	Adenosyltransferase
HUT07_RS15985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUT07_RS15995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUT07_RS16000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT07_RS16005	COG2967	ApaG domain
HUT07_RS16010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT07_RS16015	COG3738	Protein conserved in bacteria
HUT07_RS16030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT07_RS16035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT07_RS16050	COG1704	LemA family
HUT07_RS16055	COG2814	Major facilitator Superfamily
HUT07_RS16060	COG0861	Integral membrane protein TerC family
HUT07_RS16065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HUT07_RS16075	COG0642	Histidine kinase
HUT07_RS16090	COG4181	ATPase activity
HUT07_RS16095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HUT07_RS16115	COG4771	TonB-dependent receptor
HUT07_RS16125	COG0667	Aldo Keto reductase
HUT07_RS16130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUT07_RS16140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUT07_RS16145	COG4106	trans-aconitate 2-methyltransferase activity
HUT07_RS16165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT07_RS16170	COG1607	acyl-coa hydrolase
HUT07_RS16185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT07_RS16190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUT07_RS16210	COG0402	S-adenosylhomocysteine deaminase activity
HUT07_RS16215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUT07_RS16225	COG0494	nUDIX hydrolase
HUT07_RS16230	COG0653	protein targeting
HUT07_RS16235	COG0739	heme binding
HUT07_RS16245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HUT07_RS16250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT07_RS16260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT07_RS16265	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT07_RS16270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT07_RS16290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUT07_RS16295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT07_RS16305	COG3116	cell division
HUT07_RS16310	COG0275	rRNA processing
HUT07_RS16315	COG2001	Belongs to the MraZ family
HUT07_RS16350	COG1988	membrane-bound metal-dependent
HUT07_RS16355	COG0277	FAD linked oxidase domain protein
HUT07_RS16375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUT07_RS16380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT07_RS16385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT07_RS16435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT07_RS16435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT07_RS16440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT07_RS16455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT07_RS16465	COG0488	(ABC) transporter
HUT07_RS16475	COG2252	PERMEase
HUT07_RS16485	COG1960	acyl-CoA dehydrogenase activity
HUT07_RS16505	COG1696	Membrane protein involved in D-alanine export
HUT07_RS16525	COG1215	transferase activity, transferring glycosyl groups
HUT07_RS16535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUT07_RS16545	COG0463	Glycosyl transferase, family 2
HUT07_RS16555	COG1450	Type ii and iii secretion system protein
HUT07_RS16570	COG3166	PFAM Fimbrial assembly family protein
HUT07_RS16575	COG3156	type II secretion system protein K
HUT07_RS16580	COG4795	General secretion pathway protein
HUT07_RS16585	COG2165	general secretion pathway protein
HUT07_RS16590	COG4970	Tfp pilus assembly protein FimT
HUT07_RS16595	COG2165	general secretion pathway protein
HUT07_RS16600	COG1459	type II secretion system
HUT07_RS16605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUT07_RS16610	COG1404	Belongs to the peptidase S8 family
HUT07_RS16620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT07_RS16620	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT07_RS16635	COG4974	Belongs to the 'phage' integrase family
HUT07_RS16645	COG0795	lipopolysaccharide-transporting ATPase activity
HUT07_RS16655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT07_RS16670	COG0525	valine-tRNA ligase activity
HUT07_RS16690	COG1183	phosphatidylcholine synthase activity
HUT07_RS16700	COG0442	prolyl-tRNA aminoacylation
HUT07_RS16715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT07_RS16720	COG1127	ABC transporter
HUT07_RS16750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT07_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS16835	COG2076	Multidrug Resistance protein
HUT07_RS16840	COG2226	methyltransferase
HUT07_RS16845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT07_RS16865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT07_RS16875	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT07_RS16885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT07_RS16890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT07_RS16905	COG0626	cystathionine gamma-synthase activity
HUT07_RS16940	COG1573	uracil-dna glycosylase
HUT07_RS16945	COG0625	glutathione transferase activity
HUT07_RS16960	COG0513	Belongs to the DEAD box helicase family
HUT07_RS16980	COG0720	synthase
HUT07_RS16990	COG0745	RESPONSE REGULATOR receiver
HUT07_RS16995	COG2205	protein histidine kinase activity
HUT07_RS17000	COG5002	protein histidine kinase activity
HUT07_RS17005	COG0745	RESPONSE REGULATOR receiver
HUT07_RS17010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT07_RS17015	COG0785	Cytochrome C biogenesis protein
HUT07_RS17015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT07_RS17020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT07_RS17025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT07_RS17030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT07_RS17035	COG1956	GAF domain-containing protein
HUT07_RS17060	COG2226	methyltransferase
HUT07_RS17065	COG0583	DNA-binding transcription factor activity
HUT07_RS17080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT07_RS17085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT07_RS17095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT07_RS17100	COG1187	pseudouridine synthase activity
HUT07_RS17105	COG2813	Specifically methylates the guanine in position
HUT07_RS17120	COG0745	RESPONSE REGULATOR receiver
HUT07_RS17120	COG3292	Two component regulator propeller
HUT07_RS17120	COG2205	protein histidine kinase activity
HUT07_RS17135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT07_RS17190	COG0025	NhaP-type Na H and K H
HUT07_RS17200	COG3384	dioxygenase
HUT07_RS17210	COG0583	DNA-binding transcription factor activity
HUT07_RS17215	COG5001	Diguanylate cyclase
HUT07_RS17220	COG3590	peptidase
HUT07_RS17240	COG3279	Response regulator of the LytR AlgR family
HUT07_RS17245	COG3275	phosphorelay sensor kinase activity
HUT07_RS17275	COG4941	Belongs to the sigma-70 factor family
HUT07_RS17280	COG5507	3-demethylubiquinone-9 3-methyltransferase
HUT07_RS17290	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HUT07_RS17315	COG0741	lytic transglycosylase activity
HUT07_RS17320	COG1113	amino acid transport
HUT07_RS17325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUT07_RS17330	COG2814	Major facilitator Superfamily
HUT07_RS17340	COG0583	DNA-binding transcription factor activity
HUT07_RS17390	COG2267	carboxylic ester hydrolase activity
HUT07_RS17550	COG2375	cellular response to nickel ion
HUT07_RS17565	COG2353	YceI-like domain
HUT07_RS17570	COG0778	Nitroreductase
HUT07_RS17600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUT07_RS17605	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT07_RS17615	COG5383	Protein conserved in bacteria
HUT07_RS17665	COG4948	Mandelate Racemase Muconate Lactonizing
HUT07_RS17670	COG1737	Transcriptional regulator
HUT07_RS17680	COG0531	amino acid
HUT07_RS17690	COG4682	membrane
HUT07_RS17695	COG2133	pyrroloquinoline quinone binding
HUT07_RS17710	COG0668	transmembrane transport
HUT07_RS17715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT07_RS17725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT07_RS17735	COG1610	YqeY-like protein
HUT07_RS17740	COG1295	ribonuclease BN
HUT07_RS17745	COG0358	DNA primase activity
HUT07_RS17760	COG0109	protoheme IX farnesyltransferase activity
HUT07_RS17800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT07_RS17805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT07_RS17830	COG2067	long-chain fatty acid transport protein
HUT07_RS17840	COG0793	Belongs to the peptidase S41A family
HUT07_RS17845	COG4942	peptidase
HUT07_RS17855	COG2234	aminopeptidase activity
HUT07_RS17915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT07_RS17920	COG0739	heme binding
HUT07_RS17925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT07_RS17935	COG2223	nitrite transmembrane transporter activity
HUT07_RS17940	COG0708	Exodeoxyribonuclease III
HUT07_RS17945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT07_RS17960	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT07_RS17965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT07_RS17975	COG2205	protein histidine kinase activity
HUT07_RS17990	COG0840	transmembrane signaling receptor activity
HUT07_RS18010	COG4585	Histidine kinase
HUT07_RS18030	COG0583	DNA-binding transcription factor activity
HUT07_RS18040	COG1785	Belongs to the alkaline phosphatase family
HUT07_RS18045	COG1686	Belongs to the peptidase S11 family
HUT07_RS18060	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT07_RS18080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT07_RS18090	COG0511	ligase activity, forming carbon-carbon bonds
HUT07_RS18095	COG0439	Biotin carboxylase
HUT07_RS18110	COG2264	protein methyltransferase activity
HUT07_RS18120	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HUT07_RS18125	COG4589	Belongs to the CDS family
HUT07_RS18140	COG2453	phosphatase
HUT07_RS18140	COG0671	phosphoesterase, PA-phosphatase related
HUT07_RS18145	COG2267	carboxylic ester hydrolase activity
HUT07_RS18150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT07_RS18155	COG0138	bifunctional purine biosynthesis protein purh
HUT07_RS18165	COG0151	Belongs to the GarS family
HUT07_RS18175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT07_RS18180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT07_RS18185	COG2201	protein-glutamate methylesterase activity
HUT07_RS18190	COG2177	Part of the ABC transporter FtsEX involved in
HUT07_RS18195	COG2884	Cell division ATP-binding protein ftsE
HUT07_RS18205	COG3118	belongs to the thioredoxin family
HUT07_RS18210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUT07_RS18215	COG3706	GGDEF domain
HUT07_RS18225	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HUT07_RS18255	COG3209	COG3209 Rhs family protein
HUT07_RS18265	COG1652	LysM domain
HUT07_RS18270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HUT07_RS18270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HUT07_RS18275	COG1473	amidohydrolase
HUT07_RS18280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT07_RS18285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT07_RS18300	COG1289	transmembrane transporter activity
HUT07_RS18335	COG0316	Belongs to the HesB IscA family
HUT07_RS18375	COG1051	belongs to the nudix hydrolase family
HUT07_RS18390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT07_RS18395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT07_RS18400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HUT07_RS18410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HUT07_RS18415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT07_RS18420	COG0730	response to heat
HUT07_RS18430	COG0134	indole-3-glycerol-phosphate synthase activity
HUT07_RS18435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT07_RS18450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT07_RS18470	COG1597	lipid kinase activity
HUT07_RS18490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUT07_RS18495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT07_RS18505	COG2111	Na H antiporter
HUT07_RS18505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT07_RS18510	COG1006	Multisubunit Na H antiporter MnhC subunit
HUT07_RS18515	COG0651	ATP synthesis coupled electron transport
HUT07_RS18520	COG1863	multisubunit Na H antiporter MnhE subunit
HUT07_RS18525	COG2212	antiporter activity
HUT07_RS18530	COG1320	monovalent cation:proton antiporter activity
HUT07_RS18550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT07_RS18570	COG4804	nuclease activity
HUT07_RS18585	COG3104	oligopeptide transport
HUT07_RS18590	COG3483	tryptophan 2,3-dioxygenase activity
HUT07_RS18595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT07_RS18620	COG2378	regulation of single-species biofilm formation
HUT07_RS18625	COG0702	epimerase
HUT07_RS18635	COG2354	Protein conserved in bacteria
HUT07_RS18640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT07_RS18650	COG3264	Mechanosensitive ion channel
HUT07_RS18650	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HUT07_RS18665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT07_RS18680	COG3212	peptidase
HUT07_RS18685	COG0745	RESPONSE REGULATOR receiver
HUT07_RS18690	COG3850	Histidine kinase
HUT07_RS18690	COG5002	protein histidine kinase activity
HUT07_RS18700	COG1166	arginine decarboxylase activity
HUT07_RS18705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT07_RS18715	COG0596	Alpha beta hydrolase
HUT07_RS18725	COG0347	Belongs to the P(II) protein family
HUT07_RS18730	COG2960	long-chain fatty acid transporting porin activity
HUT07_RS18740	COG2960	long-chain fatty acid transporting porin activity
HUT07_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS18780	COG2207	Transcriptional regulator
HUT07_RS18825	COG0577	efflux transmembrane transporter activity
HUT07_RS18825	COG1136	(ABC) transporter
HUT07_RS18875	COG1136	(ABC) transporter
HUT07_RS18880	COG0577	efflux transmembrane transporter activity
HUT07_RS18880	COG1136	(ABC) transporter
HUT07_RS18885	COG0577	efflux transmembrane transporter activity
HUT07_RS18885	COG1136	(ABC) transporter
HUT07_RS18890	COG1132	(ABC) transporter
HUT07_RS18895	COG0515	serine threonine protein kinase
HUT07_RS18905	COG1309	transcriptional regulator
HUT07_RS18910	COG0606	chelatase, subunit chli
HUT07_RS18940	COG0561	phosphatase activity
HUT07_RS18945	COG3932	Exopolysaccharide synthesis, ExoD
HUT07_RS18975	COG1999	signal sequence binding
HUT07_RS18980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUT07_RS18985	COG1845	cytochrome c oxidase, subunit III
HUT07_RS18995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT07_RS19000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT07_RS19015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT07_RS19050	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUT07_RS19080	COG2031	fatty acid transporter
HUT07_RS19115	COG0811	peptide transport
HUT07_RS19120	COG2831	hemolysin activation secretion protein
HUT07_RS19175	COG0673	inositol 2-dehydrogenase activity
HUT07_RS19185	COG1501	Belongs to the glycosyl hydrolase 31 family
HUT07_RS19190	COG2222	sugar isomerase
HUT07_RS19195	COG1940	carbohydrate kinase activity
HUT07_RS19205	COG1349	DNA-binding transcription factor activity
HUT07_RS19210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT07_RS19215	COG2814	Major facilitator Superfamily
HUT07_RS19225	COG1040	competence protein
HUT07_RS19260	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HUT07_RS19275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT07_RS19280	COG0156	8-amino-7-oxononanoate synthase activity
HUT07_RS19285	COG2267	carboxylic ester hydrolase activity
HUT07_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS19320	COG3541	Predicted nucleotidyltransferase
HUT07_RS19325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUT07_RS19350	COG0714	Associated with various cellular activities
HUT07_RS19365	COG0754	glutathionylspermidine amidase activity
HUT07_RS19375	COG0129	dihydroxy-acid dehydratase activity
HUT07_RS19385	COG1199	ATP-dependent helicase activity
HUT07_RS19395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT07_RS19415	COG3781	membrane
HUT07_RS19445	COG0625	glutathione transferase activity
HUT07_RS19465	COG2207	Transcriptional regulator
HUT07_RS19480	COG4555	ABC transporter
HUT07_RS19490	COG3706	GGDEF domain
HUT07_RS19510	COG1131	(ABC) transporter
HUT07_RS19515	COG0842	Transport permease protein
HUT07_RS19520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT07_RS19530	COG0084	hydrolase, TatD family'
HUT07_RS19535	COG1643	Atp-dependent helicase
HUT07_RS19545	COG1187	pseudouridine synthase activity
HUT07_RS19555	COG0667	Aldo Keto reductase
HUT07_RS19575	COG0583	DNA-binding transcription factor activity
HUT07_RS19580	COG2814	Major facilitator Superfamily
HUT07_RS19585	COG0656	L-ascorbic acid biosynthetic process
HUT07_RS19590	COG2267	carboxylic ester hydrolase activity
HUT07_RS19600	COG0393	Putative heavy-metal-binding
HUT07_RS19605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT07_RS19605	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT07_RS19605	COG1042	CoA-binding domain protein
HUT07_RS19610	COG2239	Acts as a magnesium transporter
HUT07_RS19620	COG3177	Filamentation induced by cAMP protein fic
HUT07_RS19620	COG0666	response to abiotic stimulus
HUT07_RS19625	COG3100	YcgL domain-containing protein
HUT07_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
HUT07_RS19685	COG2986	histidine ammonia-lyase
HUT07_RS19695	COG0463	Glycosyl transferase, family 2
HUT07_RS19700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT07_RS19710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT07_RS19715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT07_RS19730	COG1294	oxidase, subunit
HUT07_RS19735	COG1271	oxidase subunit
HUT07_RS19755	COG1595	DNA-templated transcription, initiation
HUT07_RS19790	COG0408	coproporphyrinogen oxidase activity
HUT07_RS19795	COG2323	membrane
HUT07_RS19810	COG0589	response to stress
HUT07_RS19820	COG1690	Belongs to the RtcB family
HUT07_RS19830	COG4650	regulator
HUT07_RS19855	COG0210	DNA helicase
HUT07_RS19865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT07_RS19870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT07_RS19875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT07_RS19890	COG0251	oxidation-reduction process
HUT07_RS19925	COG0463	Glycosyl transferase, family 2
HUT07_RS19940	COG1475	DNA binding
HUT07_RS19945	COG1192	Involved in chromosome partitioning
HUT07_RS19950	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT07_RS19955	COG2091	lysine biosynthetic process via aminoadipic acid
HUT07_RS19995	COG1971	Probably functions as a manganese efflux pump
HUT07_RS20000	COG2205	protein histidine kinase activity
HUT07_RS20000	COG0784	Response regulator, receiver
HUT07_RS20010	COG0443	Heat shock 70 kDa protein
HUT07_RS20025	COG0729	surface antigen
HUT07_RS20035	COG0752	glycyl-tRNA synthetase alpha subunit
HUT07_RS20045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT07_RS20045	COG0519	Catalyzes the synthesis of GMP from XMP
HUT07_RS20055	COG0805	protein transport
HUT07_RS20065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT07_RS20075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HUT07_RS20085	COG0840	transmembrane signaling receptor activity
HUT07_RS20140	COG3135	benzoate transporter
HUT07_RS20150	COG0676	glucose-6-phosphate 1-epimerase activity
HUT07_RS20155	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT07_RS20160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT07_RS20195	COG0302	gtp cyclohydrolase
HUT07_RS20210	COG1566	PFAM secretion protein HlyD family protein
HUT07_RS20220	COG1289	transmembrane transporter activity
HUT07_RS20235	COG1074	ATP-dependent DNA helicase activity
HUT07_RS20240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUT07_RS20245	COG1127	ABC transporter
HUT07_RS20250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT07_RS20255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT07_RS20270	COG2853	Lipoprotein
HUT07_RS20275	COG0386	Belongs to the glutathione peroxidase family
HUT07_RS20285	COG1322	Protein conserved in bacteria
HUT07_RS20300	COG0583	DNA-binding transcription factor activity
HUT07_RS20315	COG0531	amino acid
HUT07_RS20335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUT07_RS20340	COG0861	Integral membrane protein TerC family
HUT07_RS20350	COG0584	glycerophosphoryl diester phosphodiesterase
HUT07_RS20365	COG0706	membrane insertase activity
HUT07_RS20370	COG0594	ribonuclease P activity
HUT07_RS20375	COG0230	Belongs to the bacterial ribosomal protein bL34 family