locus-tag	class	description
E5790_RS00010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E5790_RS00025	COG0531	amino acid
E5790_RS00030	COG0531	amino acid
E5790_RS00035	COG0235	Class ii aldolase
E5790_RS00040	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
E5790_RS00045	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
E5790_RS00060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5790_RS00070	COG1609	Transcriptional regulator
E5790_RS00075	COG3537	Alpha-1,2-mannosidase
E5790_RS00090	COG0789	Transcriptional regulator
E5790_RS00105	COG3142	Participates in the control of copper homeostasis
E5790_RS00110	COG1446	asparaginase
E5790_RS00130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E5790_RS00130	COG0140	phosphoribosyl-ATP diphosphatase activity
E5790_RS00135	COG0107	imidazoleglycerol-phosphate synthase activity
E5790_RS00140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E5790_RS00145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E5790_RS00150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E5790_RS00150	COG0131	Imidazoleglycerol-phosphate dehydratase
E5790_RS00155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E5790_RS00160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E5790_RS00165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E5790_RS00180	COG0124	histidyl-tRNA synthetase
E5790_RS00185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5790_RS00200	COG0527	aspartate kinase activity
E5790_RS00200	COG0460	homoserine dehydrogenase
E5790_RS00235	COG0640	Transcriptional regulator
E5790_RS00245	COG0745	RESPONSE REGULATOR receiver
E5790_RS00255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E5790_RS00260	COG3437	response regulator, receiver
E5790_RS00260	COG4999	Histidine kinase
E5790_RS00260	COG2205	protein histidine kinase activity
E5790_RS00260	COG3850	Histidine kinase
E5790_RS00265	COG0784	Response regulator, receiver
E5790_RS00265	COG4191	Histidine kinase
E5790_RS00315	COG1012	belongs to the aldehyde dehydrogenase family
E5790_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS00335	COG0167	dihydroorotate dehydrogenase activity
E5790_RS00340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E5790_RS00345	COG0697	spore germination
E5790_RS00360	COG1309	transcriptional regulator
E5790_RS00390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5790_RS00410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5790_RS00415	COG1126	abc transporter atp-binding protein
E5790_RS00425	COG1473	amidohydrolase
E5790_RS00430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5790_RS00435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5790_RS00445	COG0431	NADPH-dependent FMN reductase
E5790_RS00480	COG2207	Transcriptional regulator
E5790_RS00485	COG0300	oxidoreductase activity
E5790_RS00490	COG4716	Myosin-crossreactive antigen
E5790_RS00515	COG0640	Transcriptional regulator
E5790_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS00570	COG0583	DNA-binding transcription factor activity
E5790_RS00635	COG2948	multi-organism process
E5790_RS00670	COG0519	Catalyzes the synthesis of GMP from XMP
E5790_RS00670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E5790_RS00690	COG0475	glutathione-regulated potassium exporter activity
E5790_RS00690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5790_RS00695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E5790_RS00700	COG1160	GTP binding
E5790_RS00705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5790_RS00710	COG2976	Protein conserved in bacteria
E5790_RS00715	COG1426	Protein conserved in bacteria
E5790_RS00715	COG1426	Protein conserved in bacteria
E5790_RS00725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E5790_RS00730	COG0105	UTP biosynthetic process
E5790_RS00740	COG1024	Enoyl-CoA hydratase
E5790_RS00740	COG1250	3-hydroxyacyl-CoA dehydrogenase
E5790_RS00745	COG0183	Belongs to the thiolase family
E5790_RS00750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5790_RS00765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E5790_RS00775	COG0776	regulation of translation
E5790_RS00785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E5790_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E5790_RS00800	COG2957	Belongs to the agmatine deiminase family
E5790_RS00805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5790_RS00820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS00845	COG0488	(ABC) transporter
E5790_RS00850	COG0583	DNA-binding transcription factor activity
E5790_RS00860	COG0513	Belongs to the DEAD box helicase family
E5790_RS00865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E5790_RS00875	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
E5790_RS00880	COG0625	glutathione transferase activity
E5790_RS00885	COG1278	Cold shock
E5790_RS00895	COG0564	pseudouridine synthase activity
E5790_RS00900	COG4681	YaeQ
E5790_RS00905	COG2081	HI0933 family
E5790_RS00915	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E5790_RS00920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E5790_RS00930	COG1862	Preprotein translocase
E5790_RS00935	COG0343	queuine tRNA-ribosyltransferase activity
E5790_RS00940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E5790_RS00945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E5790_RS00955	COG5001	Diguanylate cyclase
E5790_RS00975	COG1132	(ABC) transporter
E5790_RS00985	COG0287	Prephenate dehydrogenase
E5790_RS00985	COG1605	Chorismate mutase
E5790_RS00995	COG2223	nitrite transmembrane transporter activity
E5790_RS01000	COG2207	Transcriptional regulator
E5790_RS01005	COG0484	heat shock protein binding
E5790_RS01010	COG0443	Heat shock 70 kDa protein
E5790_RS01015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E5790_RS01020	COG1420	regulation of RNA biosynthetic process
E5790_RS01025	COG0497	DNA recombination
E5790_RS01030	COG0583	DNA-binding transcription factor activity
E5790_RS01045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5790_RS01060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E5790_RS01165	COG2124	cytochrome p450
E5790_RS01230	COG0583	DNA-binding transcription factor activity
E5790_RS01235	COG2885	chlorophyll binding
E5790_RS01240	COG0415	Belongs to the DNA photolyase family
E5790_RS01245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E5790_RS01265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
E5790_RS01285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5790_RS01290	COG0405	Gamma-glutamyltransferase
E5790_RS01295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5790_RS01305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E5790_RS01310	COG0742	ribosomal rna small subunit methyltransferase
E5790_RS01325	COG0552	protein localization to endoplasmic reticulum
E5790_RS01330	COG1194	a g-specific adenine glycosylase
E5790_RS01335	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
E5790_RS01350	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5790_RS01370	COG1053	succinate dehydrogenase
E5790_RS01375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E5790_RS01380	COG2009	succinate dehydrogenase
E5790_RS01395	COG3842	ATPase activity
E5790_RS01400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E5790_RS01405	COG0837	glucose binding
E5790_RS01415	COG0129	dihydroxy-acid dehydratase activity
E5790_RS01420	COG0800	Aldolase
E5790_RS01430	COG0671	phosphoesterase, PA-phosphatase related
E5790_RS01435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E5790_RS01445	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
E5790_RS01450	COG0166	Belongs to the GPI family
E5790_RS01455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
E5790_RS01460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
E5790_RS01465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E5790_RS01470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5790_RS01475	COG0617	tRNA 3'-terminal CCA addition
E5790_RS01485	COG0477	Major facilitator Superfamily
E5790_RS01490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E5790_RS01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E5790_RS01510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5790_RS01515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E5790_RS01530	COG0352	thiamine-phosphate diphosphorylase activity
E5790_RS01530	COG0351	phosphomethylpyrimidine kinase
E5790_RS01555	COG0583	DNA-binding transcription factor activity
E5790_RS01560	COG1741	Belongs to the pirin family
E5790_RS01575	COG2223	nitrite transmembrane transporter activity
E5790_RS01590	COG3258	Cytochrome c
E5790_RS01605	COG3540	Alkaline phosphatase
E5790_RS01645	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E5790_RS01650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E5790_RS01655	COG2137	regulation of response to DNA damage stimulus
E5790_RS01660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E5790_RS01665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E5790_RS01670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E5790_RS01675	COG1546	Belongs to the CinA family
E5790_RS01680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E5790_RS01685	COG1923	regulation of RNA biosynthetic process
E5790_RS01690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E5790_RS01695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E5790_RS01705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E5790_RS01710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
E5790_RS01715	COG1534	Rna-binding protein
E5790_RS01740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E5790_RS01745	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
E5790_RS01750	COG2840	Smr protein MutS2
E5790_RS01760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
E5790_RS01765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E5790_RS01770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
E5790_RS01775	COG0148	phosphopyruvate hydratase activity
E5790_RS01790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
E5790_RS01795	COG0504	CTP synthase activity
E5790_RS01810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5790_RS01820	COG0306	phosphate transporter
E5790_RS01830	COG1253	flavin adenine dinucleotide binding
E5790_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5790_RS01870	COG0456	acetyltransferase
E5790_RS01875	COG0069	glutamate synthase activity
E5790_RS01880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E5790_RS01895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5790_RS01910	COG0348	domain, Protein
E5790_RS01930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E5790_RS01935	COG4977	sequence-specific DNA binding
E5790_RS01935	COG1917	Cupin 2, conserved barrel domain protein
E5790_RS01965	COG1397	ADP-ribosylglycohydrolase
E5790_RS02000	COG1136	(ABC) transporter
E5790_RS02000	COG0577	efflux transmembrane transporter activity
E5790_RS02040	COG0322	excinuclease ABC activity
E5790_RS02050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E5790_RS02055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E5790_RS02060	COG1663	tetraacyldisaccharide 4'-kinase activity
E5790_RS02075	COG0811	peptide transport
E5790_RS02080	COG0658	competence protein
E5790_RS02080	COG2333	competence protein COMEC
E5790_RS02090	COG0745	RESPONSE REGULATOR receiver
E5790_RS02095	COG3713	MltA-interacting MipA family protein
E5790_RS02120	COG0556	nucleotide-excision repair
E5790_RS02165	COG1611	Belongs to the LOG family
E5790_RS02180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5790_RS02190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5790_RS02225	COG2969	positive regulation of protein catabolic process
E5790_RS02230	COG0625	glutathione transferase activity
E5790_RS02235	COG2857	Cytochrome c1
E5790_RS02240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
E5790_RS02245	COG0723	plastoquinol--plastocyanin reductase activity
E5790_RS02250	COG0741	lytic transglycosylase activity
E5790_RS02265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E5790_RS02270	COG0842	Transport permease protein
E5790_RS02275	COG1131	(ABC) transporter
E5790_RS02285	COG1702	phosphate starvation-inducible protein PhoH
E5790_RS02290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E5790_RS02305	COG4535	Mg2 and Co2 transporter CorC
E5790_RS02320	COG1012	belongs to the aldehyde dehydrogenase family
E5790_RS02325	COG1177	transmembrane transport
E5790_RS02330	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5790_RS02335	COG3842	ATPase activity
E5790_RS02345	COG0174	glutamine synthetase
E5790_RS02350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E5790_RS02355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5790_RS02385	COG2703	oxygen carrier activity
E5790_RS02390	COG0477	Major facilitator Superfamily
E5790_RS02395	COG1012	belongs to the aldehyde dehydrogenase family
E5790_RS02400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E5790_RS02410	COG2733	membrane
E5790_RS02430	COG0116	Belongs to the methyltransferase superfamily
E5790_RS02430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E5790_RS02450	COG0494	nUDIX hydrolase
E5790_RS02460	COG1024	Enoyl-CoA hydratase
E5790_RS02470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E5790_RS02480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5790_RS02485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5790_RS02490	COG0573	inorganic phosphate transmembrane transporter activity
E5790_RS02495	COG0581	inorganic phosphate transmembrane transporter activity
E5790_RS02505	COG0704	Plays a role in the regulation of phosphate uptake
E5790_RS02515	COG3220	belongs to the UPF0276 family
E5790_RS02525	COG2259	Doxx family
E5790_RS02530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5790_RS02550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS02555	COG1136	(ABC) transporter
E5790_RS02555	COG0577	efflux transmembrane transporter activity
E5790_RS02560	COG1538	Outer membrane efflux protein
E5790_RS02565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5790_RS02575	COG0557	exoribonuclease II activity
E5790_RS02595	COG0583	DNA-binding transcription factor activity
E5790_RS02605	COG2814	Major facilitator Superfamily
E5790_RS02610	COG1566	PFAM secretion protein HlyD family protein
E5790_RS02645	COG0475	glutathione-regulated potassium exporter activity
E5790_RS02650	COG0367	asparagine synthase
E5790_RS02660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5790_RS02665	COG1393	Belongs to the ArsC family
E5790_RS02680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
E5790_RS02700	COG3188	usher protein
E5790_RS02720	COG0052	Belongs to the universal ribosomal protein uS2 family
E5790_RS02725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E5790_RS02735	COG0528	UMP kinase activity
E5790_RS02740	COG0233	cytoplasmic translational termination
E5790_RS02745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E5790_RS02750	COG0575	Belongs to the CDS family
E5790_RS02755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E5790_RS02760	COG0750	zinc metalloprotease
E5790_RS02765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5790_RS02770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E5790_RS02780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E5790_RS02785	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E5790_RS02805	COG0825	malonyl-CoA metabolic process
E5790_RS02810	COG1981	membrane
E5790_RS02830	COG1695	Transcriptional regulator
E5790_RS02885	COG1132	(ABC) transporter
E5790_RS02890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5790_RS02915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E5790_RS02925	COG1187	pseudouridine synthase activity
E5790_RS02935	COG5002	protein histidine kinase activity
E5790_RS02935	COG5001	Diguanylate cyclase
E5790_RS02975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E5790_RS03015	COG0735	belongs to the Fur family
E5790_RS03020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E5790_RS03035	COG4452	Inner membrane protein CreD
E5790_RS03040	COG2205	protein histidine kinase activity
E5790_RS03045	COG0745	RESPONSE REGULATOR receiver
E5790_RS03050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E5790_RS03060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E5790_RS03070	COG3590	peptidase
E5790_RS03080	COG0588	phosphoglycerate mutase activity
E5790_RS03100	COG3706	GGDEF domain
E5790_RS03105	COG2814	Major facilitator Superfamily
E5790_RS03130	COG1647	Serine aminopeptidase, S33
E5790_RS03140	COG2076	Multidrug Resistance protein
E5790_RS03155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E5790_RS03180	COG0024	Methionine aminopeptidase
E5790_RS03200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS03215	COG3134	Outer membrane lipoprotein
E5790_RS03220	COG0840	transmembrane signaling receptor activity
E5790_RS03240	COG0753	catalase activity
E5790_RS03260	COG0534	Mate efflux family protein
E5790_RS03280	COG0335	large ribosomal subunit rRNA binding
E5790_RS03285	COG0336	Belongs to the RNA methyltransferase TrmD family
E5790_RS03290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E5790_RS03295	COG0228	four-way junction DNA binding
E5790_RS03305	COG2070	2-Nitropropane dioxygenase
E5790_RS03310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5790_RS03330	COG0326	Molecular chaperone. Has ATPase activity
E5790_RS03345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5790_RS03350	COG1845	cytochrome c oxidase, subunit III
E5790_RS03355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E5790_RS03400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E5790_RS03600	COG3685	Protein conserved in bacteria
E5790_RS03615	COG4191	Histidine kinase
E5790_RS03615	COG0784	Response regulator, receiver
E5790_RS03675	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E5790_RS03710	COG4227	nucleotidyltransferase activity
E5790_RS03765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5790_RS03785	COG4206	TonB-dependent receptor
E5790_RS03810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E5790_RS03820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E5790_RS03825	COG0196	riboflavin kinase activity
E5790_RS03830	COG0728	peptidoglycan biosynthetic process
E5790_RS03835	COG0268	Binds directly to 16S ribosomal RNA
E5790_RS03840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E5790_RS03845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E5790_RS03850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E5790_RS03855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E5790_RS03860	COG0824	Thioesterase
E5790_RS03880	COG1946	Acyl-CoA thioesterase
E5790_RS03890	COG1595	DNA-templated transcription, initiation
E5790_RS03900	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
E5790_RS03910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E5790_RS03950	COG2197	response regulator
E5790_RS03955	COG4585	Histidine kinase
E5790_RS03970	COG2894	cell division
E5790_RS03975	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
E5790_RS03990	COG0823	Involved in the tonB-independent uptake of proteins
E5790_RS03990	COG1506	peptidase
E5790_RS03995	COG1297	OPT oligopeptide transporter protein
E5790_RS04005	COG3104	oligopeptide transport
E5790_RS04025	COG0456	acetyltransferase
E5790_RS04025	COG0454	-acetyltransferase
E5790_RS04030	COG0579	oxidoreductase
E5790_RS04045	COG3052	prosthetic group binding
E5790_RS04065	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E5790_RS04080	COG1802	Transcriptional regulator
E5790_RS04095	COG0477	Major facilitator Superfamily
E5790_RS04125	COG2259	Doxx family
E5790_RS04145	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
E5790_RS04150	COG1408	metallophosphoesterase
E5790_RS04155	COG1253	flavin adenine dinucleotide binding
E5790_RS04160	COG3655	Transcriptional regulator
E5790_RS04175	COG0640	Transcriptional regulator
E5790_RS04215	COG1609	Transcriptional regulator
E5790_RS04225	COG2211	Major facilitator Superfamily
E5790_RS04230	COG0673	inositol 2-dehydrogenase activity
E5790_RS04240	COG2010	Cytochrome c
E5790_RS04275	COG0583	DNA-binding transcription factor activity
E5790_RS04355	COG0629	single-stranded DNA binding
E5790_RS04365	COG1131	(ABC) transporter
E5790_RS04390	COG2211	Major facilitator Superfamily
E5790_RS04390	COG2190	(PTS) system
E5790_RS04400	COG1082	Xylose isomerase domain protein TIM barrel
E5790_RS04410	COG0366	Alpha amylase catalytic
E5790_RS04415	COG0142	geranyltranstransferase activity
E5790_RS04440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E5790_RS04450	COG0527	aspartate kinase activity
E5790_RS04455	COG0384	phenazine biosynthesis protein PhzF
E5790_RS04460	COG0384	phenazine biosynthesis protein PhzF
E5790_RS04465	COG1764	response to oxidative stress
E5790_RS04490	COG0693	protein deglycase activity
E5790_RS04500	COG1959	2 iron, 2 sulfur cluster binding
E5790_RS04505	COG0719	Fe-S assembly protein
E5790_RS04510	COG0396	ATPase activity
E5790_RS04515	COG0719	Fe-S assembly protein
E5790_RS04520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E5790_RS04550	COG2146	nitrite reductase [NAD(P)H] activity
E5790_RS04560	COG4774	siderophore transport
E5790_RS04570	COG3128	pkhd-type hydroxylase
E5790_RS04580	COG4771	TonB-dependent receptor
E5790_RS04600	COG1477	protein flavinylation
E5790_RS04605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E5790_RS04625	COG1555	photosystem II stabilization
E5790_RS04635	COG2261	transglycosylase associated protein
E5790_RS04640	COG3178	'Phosphotransferase
E5790_RS04645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E5790_RS04655	COG0628	permease
E5790_RS04665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E5790_RS04685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E5790_RS04705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E5790_RS04720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E5790_RS04735	COG1137	ATPase activity
E5790_RS04745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E5790_RS04750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5790_RS04755	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
E5790_RS04760	COG1660	Displays ATPase and GTPase activities
E5790_RS04775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5790_RS04780	COG2239	Acts as a magnesium transporter
E5790_RS04800	COG0540	Belongs to the ATCase OTCase family
E5790_RS04805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E5790_RS04810	COG1678	Uncharacterized ACR, COG1678
E5790_RS04815	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5790_RS04820	COG2818	Glycosylase
E5790_RS04840	COG0667	Aldo Keto reductase
E5790_RS04855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5790_RS04865	COG0583	DNA-binding transcription factor activity
E5790_RS04900	COG0477	Major facilitator Superfamily
E5790_RS04905	COG0583	DNA-binding transcription factor activity
E5790_RS04910	COG0697	spore germination
E5790_RS04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5790_RS04920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E5790_RS04935	COG2223	nitrite transmembrane transporter activity
E5790_RS04945	COG4774	siderophore transport
E5790_RS04990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E5790_RS04995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E5790_RS05000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E5790_RS05005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5790_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS05020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E5790_RS05030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E5790_RS05035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E5790_RS05040	COG1399	metal-binding, possibly nucleic acid-binding protein
E5790_RS05055	COG0714	Associated with various cellular activities
E5790_RS05075	COG0537	adenosine 5'-monophosphoramidase activity
E5790_RS05085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E5790_RS05105	COG2885	chlorophyll binding
E5790_RS05105	COG3047	cAMP biosynthetic process
E5790_RS05185	COG2076	Multidrug Resistance protein
E5790_RS05200	COG1234	tRNA 3'-trailer cleavage
E5790_RS05205	COG3642	lipopolysaccharide core region biosynthetic process
E5790_RS05210	COG0859	PFAM glycosyl transferase family 9
E5790_RS05225	COG0631	protein serine/threonine phosphatase activity
E5790_RS05230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5790_RS05235	COG0328	RNA-DNA hybrid ribonuclease activity
E5790_RS05245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5790_RS05250	COG1388	LysM domain
E5790_RS05250	COG3942	CHAP domain
E5790_RS05255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5790_RS05295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
E5790_RS05300	COG0740	serine-type endopeptidase activity
E5790_RS05305	COG0544	peptidyl-prolyl cis-trans isomerase activity
E5790_RS05370	COG0473	3-isopropylmalate dehydrogenase activity
E5790_RS05385	COG4783	chaperone-mediated protein folding
E5790_RS05400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E5790_RS05405	COG0248	Ppx GppA phosphatase
E5790_RS05410	COG4206	TonB-dependent receptor
E5790_RS05415	COG0438	transferase activity, transferring glycosyl groups
E5790_RS05420	COG0671	phosphoesterase, PA-phosphatase related
E5790_RS05425	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E5790_RS05430	COG3291	Pkd domain containing protein
E5790_RS05440	COG2833	Protein of unknown function (DUF455)
E5790_RS05460	COG0285	dihydrofolate synthase activity
E5790_RS05465	COG0588	phosphoglycerate mutase activity
E5790_RS05475	COG1063	alcohol dehydrogenase
E5790_RS05495	COG1187	pseudouridine synthase activity
E5790_RS05510	COG0604	alcohol dehydrogenase
E5790_RS05515	COG2364	Membrane
E5790_RS05520	COG0446	pyridine nucleotide-disulphide oxidoreductase
E5790_RS05520	COG1902	pentaerythritol trinitrate reductase activity
E5790_RS05530	COG0625	glutathione transferase activity
E5790_RS05545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E5790_RS05550	COG0564	pseudouridine synthase activity
E5790_RS05555	COG0039	L-malate dehydrogenase activity
E5790_RS05560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E5790_RS05575	COG0154	amidase activity
E5790_RS05585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
E5790_RS05600	COG0203	ribosomal protein L17
E5790_RS05605	COG0202	RNA polymerase activity
E5790_RS05610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E5790_RS05615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E5790_RS05620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E5790_RS05625	COG0201	protein transport
E5790_RS05630	COG0200	Binds to the 23S rRNA
E5790_RS05635	COG1841	ribosomal large subunit assembly
E5790_RS05640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E5790_RS05645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E5790_RS05650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E5790_RS05655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E5790_RS05660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E5790_RS05665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E5790_RS05670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E5790_RS05675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E5790_RS05680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E5790_RS05685	COG0255	Belongs to the universal ribosomal protein uL29 family
E5790_RS05690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E5790_RS05695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E5790_RS05700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E5790_RS05705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E5790_RS05710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E5790_RS05715	COG0089	rRNA binding
E5790_RS05720	COG0088	Forms part of the polypeptide exit tunnel
E5790_RS05725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E5790_RS05730	COG0051	transcription antitermination factor activity, RNA binding
E5790_RS05735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E5790_RS05740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E5790_RS05745	COG0049	tRNA binding
E5790_RS05750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E5790_RS05755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E5790_RS05760	COG0085	RNA polymerase activity
E5790_RS05765	COG0222	ribosome binding
E5790_RS05770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E5790_RS05780	COG0081	regulation of translation
E5790_RS05785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E5790_RS05790	COG0250	Participates in transcription elongation, termination and antitermination
E5790_RS05795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5790_RS05805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E5790_RS05830	COG4242	Belongs to the peptidase S51 family
E5790_RS05835	COG4206	TonB-dependent receptor
E5790_RS05840	COG0012	GTP binding
E5790_RS05850	COG0193	aminoacyl-tRNA hydrolase activity
E5790_RS05855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E5790_RS05860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E5790_RS05870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E5790_RS05885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E5790_RS05890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E5790_RS05905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5790_RS05910	COG1295	ribonuclease BN
E5790_RS05930	COG1404	Belongs to the peptidase S8 family
E5790_RS05935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5790_RS05975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E5790_RS06030	COG3634	alkyl hydroperoxide reductase activity
E5790_RS06035	COG0583	DNA-binding transcription factor activity
E5790_RS06040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5790_RS06050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E5790_RS06060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E5790_RS06080	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
E5790_RS06090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5790_RS06095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5790_RS06105	COG2096	Adenosyltransferase
E5790_RS06115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E5790_RS06120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5790_RS06125	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E5790_RS06130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E5790_RS06135	COG2967	ApaG domain
E5790_RS06140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E5790_RS06145	COG3738	Protein conserved in bacteria
E5790_RS06155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E5790_RS06160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E5790_RS06175	COG1704	LemA family
E5790_RS06180	COG2814	Major facilitator Superfamily
E5790_RS06185	COG0861	Integral membrane protein TerC family
E5790_RS06190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5790_RS06200	COG0642	Histidine kinase
E5790_RS06215	COG4181	ATPase activity
E5790_RS06220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E5790_RS06235	COG4771	TonB-dependent receptor
E5790_RS06245	COG0667	Aldo Keto reductase
E5790_RS06250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E5790_RS06255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5790_RS06265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E5790_RS06270	COG4106	trans-aconitate 2-methyltransferase activity
E5790_RS06290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E5790_RS06295	COG1607	acyl-coa hydrolase
E5790_RS06300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
E5790_RS06310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
E5790_RS06320	COG3773	Cell wall hydrolase
E5790_RS06320	COG3409	Peptidoglycan-binding domain 1 protein
E5790_RS06325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5790_RS06350	COG3275	phosphorelay sensor kinase activity
E5790_RS06360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E5790_RS06370	COG0494	nUDIX hydrolase
E5790_RS06375	COG0653	protein targeting
E5790_RS06380	COG0739	heme binding
E5790_RS06390	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
E5790_RS06395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E5790_RS06405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E5790_RS06410	COG1181	Belongs to the D-alanine--D-alanine ligase family
E5790_RS06415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5790_RS06435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E5790_RS06450	COG3116	cell division
E5790_RS06455	COG0275	rRNA processing
E5790_RS06460	COG2001	Belongs to the MraZ family
E5790_RS06500	COG1988	membrane-bound metal-dependent
E5790_RS06505	COG0277	FAD linked oxidase domain protein
E5790_RS06510	COG2755	lipolytic protein G-D-S-L family
E5790_RS06510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E5790_RS06530	COG3152	Membrane
E5790_RS06540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E5790_RS06545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E5790_RS06575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5790_RS06575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5790_RS06580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E5790_RS06600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E5790_RS06610	COG0488	(ABC) transporter
E5790_RS06615	COG2252	PERMEase
E5790_RS06640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E5790_RS06655	COG3121	Chaperone
E5790_RS06660	COG3539	Fimbrial protein
E5790_RS06685	COG1450	Type ii and iii secretion system protein
E5790_RS06700	COG3166	PFAM Fimbrial assembly family protein
E5790_RS06705	COG3156	type II secretion system protein K
E5790_RS06710	COG4795	General secretion pathway protein
E5790_RS06715	COG2165	general secretion pathway protein
E5790_RS06720	COG4970	Tfp pilus assembly protein FimT
E5790_RS06725	COG2165	general secretion pathway protein
E5790_RS06730	COG1459	type II secretion system
E5790_RS06735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5790_RS06740	COG1404	Belongs to the peptidase S8 family
E5790_RS06745	COG5295	Hep Hag repeat protein
E5790_RS06755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E5790_RS06755	COG0047	phosphoribosylformylglycinamidine synthase activity
E5790_RS06765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5790_RS06770	COG4974	Belongs to the 'phage' integrase family
E5790_RS06780	COG0795	lipopolysaccharide-transporting ATPase activity
E5790_RS06790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E5790_RS06805	COG0525	valine-tRNA ligase activity
E5790_RS06815	COG0456	acetyltransferase
E5790_RS06825	COG1183	phosphatidylcholine synthase activity
E5790_RS06835	COG0442	prolyl-tRNA aminoacylation
E5790_RS06850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5790_RS06855	COG1127	ABC transporter
E5790_RS06890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E5790_RS06940	COG0546	phosphoglycolate phosphatase activity
E5790_RS06940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
E5790_RS06950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E5790_RS06965	COG1216	Glycosyl transferase, family 2
E5790_RS06965	COG0463	Glycosyl transferase, family 2
E5790_RS06990	COG0626	cystathionine gamma-synthase activity
E5790_RS07025	COG1573	uracil-dna glycosylase
E5790_RS07030	COG0625	glutathione transferase activity
E5790_RS07045	COG0513	Belongs to the DEAD box helicase family
E5790_RS07060	COG0720	synthase
E5790_RS07070	COG0367	asparagine synthase
E5790_RS07075	COG0745	RESPONSE REGULATOR receiver
E5790_RS07080	COG2205	protein histidine kinase activity
E5790_RS07085	COG5002	protein histidine kinase activity
E5790_RS07090	COG0745	RESPONSE REGULATOR receiver
E5790_RS07095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E5790_RS07100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5790_RS07100	COG0785	Cytochrome C biogenesis protein
E5790_RS07105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E5790_RS07110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5790_RS07115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E5790_RS07120	COG1956	GAF domain-containing protein
E5790_RS07145	COG2226	methyltransferase
E5790_RS07150	COG0583	DNA-binding transcription factor activity
E5790_RS07165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E5790_RS07170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E5790_RS07180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5790_RS07185	COG1187	pseudouridine synthase activity
E5790_RS07190	COG2813	Specifically methylates the guanine in position
E5790_RS07205	COG5002	protein histidine kinase activity
E5790_RS07220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5790_RS07250	COG1360	Flagellar Motor Protein
E5790_RS07275	COG0025	NhaP-type Na H and K H
E5790_RS07280	COG3384	dioxygenase
E5790_RS07290	COG0583	DNA-binding transcription factor activity
E5790_RS07295	COG5001	Diguanylate cyclase
E5790_RS07300	COG3590	peptidase
E5790_RS07305	COG2814	Major facilitator Superfamily
E5790_RS07315	COG1309	transcriptional regulator
E5790_RS07335	COG3279	Response regulator of the LytR AlgR family
E5790_RS07340	COG3275	phosphorelay sensor kinase activity
E5790_RS07370	COG4941	Belongs to the sigma-70 factor family
E5790_RS07375	COG5507	3-demethylubiquinone-9 3-methyltransferase
E5790_RS07385	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E5790_RS07395	COG3795	YCII-related domain
E5790_RS07410	COG0741	lytic transglycosylase activity
E5790_RS07415	COG1113	amino acid transport
E5790_RS07420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5790_RS07425	COG2814	Major facilitator Superfamily
E5790_RS07435	COG0583	DNA-binding transcription factor activity
E5790_RS07440	COG0488	(ABC) transporter
E5790_RS07495	COG2267	carboxylic ester hydrolase activity
E5790_RS07595	COG0270	DNA (cytosine-5-)-methyltransferase activity
E5790_RS07625	COG2375	cellular response to nickel ion
E5790_RS07640	COG2353	YceI-like domain
E5790_RS07645	COG0778	Nitroreductase
E5790_RS07675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5790_RS07680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E5790_RS07690	COG5383	Protein conserved in bacteria
E5790_RS07740	COG4948	Mandelate Racemase Muconate Lactonizing
E5790_RS07745	COG1737	Transcriptional regulator
E5790_RS07755	COG0531	amino acid
E5790_RS07765	COG4682	membrane
E5790_RS07770	COG2133	pyrroloquinoline quinone binding
E5790_RS07785	COG0668	transmembrane transport
E5790_RS07790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E5790_RS07800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E5790_RS07815	COG1295	ribonuclease BN
E5790_RS07820	COG0358	DNA primase activity
E5790_RS07840	COG0109	protoheme IX farnesyltransferase activity
E5790_RS07885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5790_RS07910	COG2067	long-chain fatty acid transport protein
E5790_RS07920	COG0793	Belongs to the peptidase S41A family
E5790_RS07925	COG4942	peptidase
E5790_RS07935	COG2234	aminopeptidase activity
E5790_RS07995	COG3135	benzoate transporter
E5790_RS08015	COG2951	lytic endotransglycosylase activity
E5790_RS08020	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
E5790_RS08025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E5790_RS08030	COG3706	GGDEF domain
E5790_RS08060	COG0302	gtp cyclohydrolase
E5790_RS08100	COG1074	ATP-dependent DNA helicase activity
E5790_RS08105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E5790_RS08110	COG1127	ABC transporter
E5790_RS08115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5790_RS08120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5790_RS08135	COG2853	Lipoprotein
E5790_RS08140	COG0386	Belongs to the glutathione peroxidase family
E5790_RS08150	COG1322	Protein conserved in bacteria
E5790_RS08160	COG0604	alcohol dehydrogenase
E5790_RS08165	COG0583	DNA-binding transcription factor activity
E5790_RS08185	COG0667	Aldo Keto reductase
E5790_RS08190	COG0531	amino acid
E5790_RS08200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E5790_RS08205	COG0861	Integral membrane protein TerC family
E5790_RS08215	COG0584	glycerophosphoryl diester phosphodiesterase
E5790_RS08230	COG0706	membrane insertase activity
E5790_RS08235	COG0594	ribonuclease P activity
E5790_RS08240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E5790_RS08245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E5790_RS08255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E5790_RS08260	COG0187	DNA topoisomerase II activity
E5790_RS08265	COG1266	CAAX protease self-immunity
E5790_RS08270	COG0501	Belongs to the peptidase M48B family
E5790_RS08300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5790_RS08380	COG0659	secondary active sulfate transmembrane transporter activity
E5790_RS08395	COG0798	PFAM Bile acid sodium symporter
E5790_RS08410	COG0431	NADPH-dependent FMN reductase
E5790_RS08425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5790_RS08445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E5790_RS08460	COG3453	Protein conserved in bacteria
E5790_RS08460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5790_RS08480	COG0640	Transcriptional regulator
E5790_RS08520	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E5790_RS08530	COG4772	TonB-dependent receptor
E5790_RS08565	COG0800	Aldolase
E5790_RS08575	COG1609	Transcriptional regulator
E5790_RS08580	COG3186	Phenylalanine-4-hydroxylase
E5790_RS08585	COG1522	sequence-specific DNA binding
E5790_RS08590	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5790_RS08600	COG4771	TonB-dependent receptor
E5790_RS08605	COG0671	phosphoesterase, PA-phosphatase related
E5790_RS08620	COG1122	ATPase activity
E5790_RS08640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E5790_RS08645	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
E5790_RS08665	COG0210	DNA helicase
E5790_RS08675	COG3132	Protein of unknown function, DUF480
E5790_RS08680	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E5790_RS08685	COG0284	orotidine-5'-phosphate decarboxylase activity
E5790_RS08690	COG5640	endopeptidase activity
E5790_RS08700	COG2937	Belongs to the GPAT DAPAT family
E5790_RS08710	COG0037	tRNA processing
E5790_RS08715	COG2974	May be involved in recombination
E5790_RS08725	COG1803	Methylglyoxal synthase
E5790_RS08730	COG2205	protein histidine kinase activity
E5790_RS08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5790_RS08735	COG0493	'glutamate synthase
E5790_RS08740	COG0070	glutamate synthase
E5790_RS08740	COG0069	glutamate synthase activity
E5790_RS08740	COG0067	glutamate synthase
E5790_RS08760	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS08775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5790_RS08800	COG1205	dead DEAH box helicase
E5790_RS08800	COG1111	helicase
E5790_RS08835	COG0714	Associated with various cellular activities
E5790_RS08855	COG0312	modulator of DNA gyrase
E5790_RS08875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E5790_RS08895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5790_RS08920	COG1881	PFAM PEBP family protein
E5790_RS08925	COG0431	NADPH-dependent FMN reductase
E5790_RS08935	COG1968	undecaprenyl-diphosphatase activity
E5790_RS08940	COG0174	glutamine synthetase
E5790_RS08945	COG0347	Belongs to the P(II) protein family
E5790_RS08950	COG0004	ammonium transporteR
E5790_RS08975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E5790_RS08990	COG3852	Histidine kinase
E5790_RS08995	COG2204	response regulator
E5790_RS09000	COG2032	superoxide dismutase activity
E5790_RS09005	COG2032	superoxide dismutase activity
E5790_RS09015	COG0183	Belongs to the thiolase family
E5790_RS09050	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E5790_RS09055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E5790_RS09075	COG0798	PFAM Bile acid sodium symporter
E5790_RS09080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E5790_RS09090	COG0431	NADPH-dependent FMN reductase
E5790_RS09130	COG2837	iron assimilation
E5790_RS09175	COG2197	response regulator
E5790_RS09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5790_RS09180	COG2205	protein histidine kinase activity
E5790_RS09185	COG3474	cytochrome
E5790_RS09195	COG1960	acyl-CoA dehydrogenase activity
E5790_RS09200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E5790_RS09210	COG0612	Peptidase, M16
E5790_RS09220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E5790_RS09225	COG0596	Alpha beta hydrolase
E5790_RS09235	COG0318	PFAM AMP-dependent synthetase and ligase
E5790_RS09240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5790_RS09250	COG1181	Belongs to the D-alanine--D-alanine ligase family
E5790_RS09260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E5790_RS09275	COG1215	transferase activity, transferring glycosyl groups
E5790_RS09280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E5790_RS09285	COG4122	O-methyltransferase activity
E5790_RS09310	COG0339	signal peptide processing
E5790_RS09325	COG0681	Belongs to the peptidase S26 family
E5790_RS09330	COG2814	Major facilitator Superfamily
E5790_RS09335	COG0583	DNA-binding transcription factor activity
E5790_RS09340	COG0583	DNA-binding transcription factor activity
E5790_RS09345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E5790_RS09350	COG2224	Isocitrate lyase
E5790_RS09380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E5790_RS09385	COG1960	acyl-CoA dehydrogenase activity
E5790_RS09405	COG0697	spore germination
E5790_RS09415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E5790_RS09435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E5790_RS09440	COG1280	lysine exporter protein (LysE YggA)
E5790_RS09445	COG1607	acyl-coa hydrolase
E5790_RS09455	COG1902	pentaerythritol trinitrate reductase activity
E5790_RS09470	COG1335	isochorismatase
E5790_RS09475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E5790_RS09485	COG1051	belongs to the nudix hydrolase family
E5790_RS09485	COG1056	cytidyltransferase-related domain
E5790_RS09490	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5790_RS09495	COG3800	Transcriptional regulator
E5790_RS09495	COG1396	sequence-specific DNA binding
E5790_RS09505	COG1960	acyl-CoA dehydrogenase activity
E5790_RS09510	COG1024	Enoyl-CoA hydratase
E5790_RS09515	COG1024	Enoyl-CoA hydratase
E5790_RS09525	COG1764	response to oxidative stress
E5790_RS09645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E5790_RS09665	COG3228	Belongs to the MtfA family
E5790_RS09675	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E5790_RS09675	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E5790_RS09680	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
E5790_RS09780	COG3237	CsbD-like
E5790_RS09790	COG0180	Tryptophanyl-tRNA synthetase
E5790_RS09815	COG0477	Major facilitator Superfamily
E5790_RS09820	COG0697	spore germination
E5790_RS09830	COG4771	TonB-dependent receptor
E5790_RS09840	COG1136	(ABC) transporter
E5790_RS09840	COG0577	efflux transmembrane transporter activity
E5790_RS09850	COG1136	(ABC) transporter
E5790_RS09855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS09860	COG4585	Histidine kinase
E5790_RS09865	COG2197	response regulator
E5790_RS09870	COG3038	cytochrome b561
E5790_RS09880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E5790_RS09895	COG0628	permease
E5790_RS09915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5790_RS09930	COG5507	3-demethylubiquinone-9 3-methyltransferase
E5790_RS09955	COG2814	Major facilitator Superfamily
E5790_RS09960	COG0583	DNA-binding transcription factor activity
E5790_RS09965	COG4807	Protein conserved in bacteria
E5790_RS09970	COG4221	oxidoreductase activity
E5790_RS09980	COG0018	arginyl-trna synthetase
E5790_RS09985	COG2003	Belongs to the UPF0758 family
E5790_RS09990	COG2197	response regulator
E5790_RS09995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E5790_RS10015	COG2205	protein histidine kinase activity
E5790_RS10025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
E5790_RS10030	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
E5790_RS10045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E5790_RS10050	COG0708	Exodeoxyribonuclease III
E5790_RS10055	COG2211	Major facilitator Superfamily
E5790_RS10070	COG0739	heme binding
E5790_RS10130	COG0840	transmembrane signaling receptor activity
E5790_RS10140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
E5790_RS10150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E5790_RS10160	COG0805	protein transport
E5790_RS10170	COG0519	Catalyzes the synthesis of GMP from XMP
E5790_RS10170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E5790_RS10175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5790_RS10180	COG0752	glycyl-tRNA synthetase alpha subunit
E5790_RS10190	COG0729	surface antigen
E5790_RS10210	COG0443	Heat shock 70 kDa protein
E5790_RS10220	COG2205	protein histidine kinase activity
E5790_RS10220	COG0784	Response regulator, receiver
E5790_RS10225	COG1971	Probably functions as a manganese efflux pump
E5790_RS10230	COG1943	Transposase
E5790_RS10270	COG2091	lysine biosynthetic process via aminoadipic acid
E5790_RS10275	COG0357	Ribosomal RNA small subunit methyltransferase G
E5790_RS10280	COG1192	Involved in chromosome partitioning
E5790_RS10285	COG1475	DNA binding
E5790_RS10300	COG0463	Glycosyl transferase, family 2
E5790_RS10335	COG0251	oxidation-reduction process
E5790_RS10350	COG1819	glycosyl
E5790_RS10355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E5790_RS10360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E5790_RS10370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5790_RS10380	COG0210	DNA helicase
E5790_RS10395	COG0589	response to stress
E5790_RS10410	COG2323	membrane
E5790_RS10420	COG0408	coproporphyrinogen oxidase activity
E5790_RS10460	COG1595	DNA-templated transcription, initiation
E5790_RS10470	COG1271	oxidase subunit
E5790_RS10475	COG1294	oxidase, subunit
E5790_RS10490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E5790_RS10495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E5790_RS10510	COG0463	Glycosyl transferase, family 2
E5790_RS10520	COG2986	histidine ammonia-lyase
E5790_RS10540	COG0644	oxidoreductase
E5790_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS10565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5790_RS10575	COG3100	YcgL domain-containing protein
E5790_RS10580	COG3177	Filamentation induced by cAMP protein fic
E5790_RS10580	COG0666	response to abiotic stimulus
E5790_RS10595	COG2239	Acts as a magnesium transporter
E5790_RS10600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5790_RS10600	COG1042	CoA-binding domain protein
E5790_RS10600	COG0045	succinate-CoA ligase (ADP-forming) activity
E5790_RS10605	COG0393	Putative heavy-metal-binding
E5790_RS10610	COG2267	carboxylic ester hydrolase activity
E5790_RS10615	COG0656	L-ascorbic acid biosynthetic process
E5790_RS10620	COG0840	transmembrane signaling receptor activity
E5790_RS10635	COG1690	Belongs to the RtcB family
E5790_RS10650	COG0667	Aldo Keto reductase
E5790_RS10660	COG1187	pseudouridine synthase activity
E5790_RS10670	COG1643	Atp-dependent helicase
E5790_RS10675	COG0084	hydrolase, TatD family'
E5790_RS10685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E5790_RS10695	COG0842	Transport permease protein
E5790_RS10700	COG1131	(ABC) transporter
E5790_RS10705	COG0543	2 iron, 2 sulfur cluster binding
E5790_RS10705	COG0633	Ferredoxin
E5790_RS10865	COG4555	ABC transporter
E5790_RS10880	COG2207	Transcriptional regulator
E5790_RS10900	COG0625	glutathione transferase activity
E5790_RS10930	COG3781	membrane
E5790_RS10950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E5790_RS10960	COG1199	ATP-dependent helicase activity
E5790_RS10965	COG0129	dihydroxy-acid dehydratase activity
E5790_RS10975	COG0754	glutathionylspermidine amidase activity
E5790_RS10990	COG0714	Associated with various cellular activities
E5790_RS11015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5790_RS11020	COG3541	Predicted nucleotidyltransferase
E5790_RS11025	COG0745	RESPONSE REGULATOR receiver
E5790_RS11030	COG2205	protein histidine kinase activity
E5790_RS11035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS11040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS11065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E5790_RS11085	COG2267	carboxylic ester hydrolase activity
E5790_RS11090	COG0156	8-amino-7-oxononanoate synthase activity
E5790_RS11095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E5790_RS11130	COG2814	Major facilitator Superfamily
E5790_RS11135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5790_RS11140	COG1349	DNA-binding transcription factor activity
E5790_RS11150	COG1940	carbohydrate kinase activity
E5790_RS11155	COG2222	sugar isomerase
E5790_RS11160	COG1501	Belongs to the glycosyl hydrolase 31 family
E5790_RS11170	COG0673	inositol 2-dehydrogenase activity
E5790_RS11230	COG2031	fatty acid transporter
E5790_RS11290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5790_RS11305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5790_RS11310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5790_RS11320	COG1845	cytochrome c oxidase, subunit III
E5790_RS11325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5790_RS11330	COG1999	signal sequence binding
E5790_RS11360	COG3932	Exopolysaccharide synthesis, ExoD
E5790_RS11365	COG0561	phosphatase activity
E5790_RS11385	COG0606	chelatase, subunit chli
E5790_RS11470	COG2960	long-chain fatty acid transporting porin activity
E5790_RS11490	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
E5790_RS11495	COG1166	arginine decarboxylase activity
E5790_RS11530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5790_RS11545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
E5790_RS11545	COG3264	Mechanosensitive ion channel
E5790_RS11565	COG2354	Protein conserved in bacteria
E5790_RS11580	COG2378	regulation of single-species biofilm formation
E5790_RS11610	COG3483	tryptophan 2,3-dioxygenase activity
E5790_RS11615	COG3104	oligopeptide transport
E5790_RS11640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
E5790_RS11655	COG0530	calcium, potassium:sodium antiporter activity
E5790_RS11660	COG1320	monovalent cation:proton antiporter activity
E5790_RS11665	COG2212	antiporter activity
E5790_RS11670	COG1863	multisubunit Na H antiporter MnhE subunit
E5790_RS11675	COG0651	ATP synthesis coupled electron transport
E5790_RS11680	COG1006	Multisubunit Na H antiporter MnhC subunit
E5790_RS11685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E5790_RS11685	COG2111	Na H antiporter
E5790_RS11695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E5790_RS11700	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E5790_RS11715	COG1597	lipid kinase activity
E5790_RS11735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E5790_RS11740	COG0134	indole-3-glycerol-phosphate synthase activity
E5790_RS11750	COG0730	response to heat
E5790_RS11755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5790_RS11760	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
E5790_RS11770	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
E5790_RS11775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E5790_RS11780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E5790_RS11795	COG1051	belongs to the nudix hydrolase family
E5790_RS11835	COG0316	Belongs to the HesB IscA family
E5790_RS11865	COG2814	Major facilitator Superfamily
E5790_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS11875	COG1289	transmembrane transporter activity
E5790_RS11880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS11885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS11890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS11895	COG1473	amidohydrolase
E5790_RS11905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E5790_RS11905	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E5790_RS11910	COG1652	LysM domain
E5790_RS11920	COG3209	COG3209 Rhs family protein
E5790_RS11960	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
E5790_RS11970	COG3706	GGDEF domain
E5790_RS11975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E5790_RS11980	COG3118	belongs to the thioredoxin family
E5790_RS11995	COG2884	Cell division ATP-binding protein ftsE
E5790_RS12000	COG2177	Part of the ABC transporter FtsEX involved in
E5790_RS12005	COG2201	protein-glutamate methylesterase activity
E5790_RS12010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E5790_RS12015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E5790_RS12030	COG0151	Belongs to the GarS family
E5790_RS12035	COG0138	bifunctional purine biosynthesis protein purh
E5790_RS12040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E5790_RS12045	COG2267	carboxylic ester hydrolase activity
E5790_RS12050	COG0671	phosphoesterase, PA-phosphatase related
E5790_RS12050	COG2453	phosphatase
E5790_RS12060	COG0204	Acyl-transferase
E5790_RS12065	COG4589	Belongs to the CDS family
E5790_RS12070	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
E5790_RS12080	COG2264	protein methyltransferase activity
E5790_RS12095	COG0439	Biotin carboxylase
E5790_RS12100	COG0511	ligase activity, forming carbon-carbon bonds
E5790_RS12110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E5790_RS12120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E5790_RS12130	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5790_RS12140	COG1686	Belongs to the peptidase S11 family
E5790_RS12150	COG0583	DNA-binding transcription factor activity
E5790_RS12170	COG0840	transmembrane signaling receptor activity
E5790_RS12180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5790_RS12190	COG1324	tolerance protein
E5790_RS12195	COG2356	endonuclease I
E5790_RS12200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E5790_RS12205	COG0459	protein refolding
E5790_RS12235	COG1846	Transcriptional regulator
E5790_RS12255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5790_RS12260	COG2860	membrane
E5790_RS12280	COG1252	NADH dehydrogenase
E5790_RS12290	COG0625	glutathione transferase activity
E5790_RS12295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E5790_RS12310	COG0534	Mate efflux family protein
E5790_RS12315	COG0616	signal peptide processing
E5790_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS12340	COG0009	L-threonylcarbamoyladenylate synthase
E5790_RS12345	COG1754	DNA topoisomerase type I activity
E5790_RS12345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5790_RS12350	COG1714	RDD family
E5790_RS12360	COG2922	Belongs to the Smg family
E5790_RS12365	COG0758	DNA mediated transformation
E5790_RS12375	COG0242	peptide deformylase activity
E5790_RS12380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E5790_RS12385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E5790_RS12385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E5790_RS12420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E5790_RS12430	COG1490	D-aminoacyl-tRNA deacylase activity
E5790_RS12435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E5790_RS12455	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
E5790_RS12480	COG2259	Doxx family
E5790_RS12525	COG2815	serine threonine protein kinase
E5790_RS12525	COG0515	serine threonine protein kinase
E5790_RS12530	COG1132	(ABC) transporter
E5790_RS12535	COG1136	(ABC) transporter
E5790_RS12535	COG0577	efflux transmembrane transporter activity
E5790_RS12540	COG1136	(ABC) transporter
E5790_RS12540	COG0577	efflux transmembrane transporter activity
E5790_RS12545	COG1136	(ABC) transporter
E5790_RS12605	COG0840	transmembrane signaling receptor activity
E5790_RS12615	COG4771	TonB-dependent receptor
E5790_RS12630	COG0400	carboxylic ester hydrolase activity
E5790_RS12635	COG0745	RESPONSE REGULATOR receiver
E5790_RS12635	COG2972	Histidine kinase
E5790_RS12645	COG0181	hydroxymethylbilane synthase activity
E5790_RS12670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E5790_RS12690	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5790_RS12695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5790_RS12710	COG0356	it plays a direct role in the translocation of protons across the membrane
E5790_RS12720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E5790_RS12725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E5790_RS12730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E5790_RS12735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E5790_RS12740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E5790_RS12745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E5790_RS12760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E5790_RS12770	COG4191	Histidine kinase
E5790_RS12795	COG1136	(ABC) transporter
E5790_RS12805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5790_RS12810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E5790_RS12810	COG0517	IMP dehydrogenase activity
E5790_RS12825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E5790_RS12835	COG0339	signal peptide processing
E5790_RS12850	COG1666	GTP binding
E5790_RS12855	COG0697	spore germination
E5790_RS12890	COG1505	serine-type exopeptidase activity
E5790_RS12895	COG0436	Aminotransferase
E5790_RS12905	COG2832	Protein of unknown function (DUF454)
E5790_RS12915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E5790_RS12930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
E5790_RS12940	COG0673	inositol 2-dehydrogenase activity
E5790_RS12950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS12955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS12985	COG2226	methyltransferase
E5790_RS12990	COG0308	aminopeptidase N
E5790_RS13005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5790_RS13010	COG1077	Cell shape determining protein MreB Mrl
E5790_RS13015	COG1792	Involved in formation and maintenance of cell shape
E5790_RS13030	COG0772	Belongs to the SEDS family
E5790_RS13035	COG0772	Belongs to the SEDS family
E5790_RS13040	COG2951	lytic endotransglycosylase activity
E5790_RS13045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E5790_RS13050	COG1686	Belongs to the peptidase S11 family
E5790_RS13060	COG2921	Belongs to the UPF0250 family
E5790_RS13065	COG0321	lipoyl(octanoyl) transferase activity
E5790_RS13070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E5790_RS13090	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
E5790_RS13095	COG0673	inositol 2-dehydrogenase activity
E5790_RS13100	COG2823	Periplasmic or secreted lipoprotein
E5790_RS13105	COG4251	negative regulation of phosphorylation
E5790_RS13110	COG0784	Response regulator, receiver
E5790_RS13115	COG4191	Histidine kinase
E5790_RS13125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5790_RS13145	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E5790_RS13155	COG0837	glucose binding
E5790_RS13165	COG1609	Transcriptional regulator
E5790_RS13170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5790_RS13175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5790_RS13185	COG3468	outer membrane autotransporter barrel domain protein
E5790_RS13215	COG0617	tRNA 3'-terminal CCA addition
E5790_RS13235	COG4206	TonB-dependent receptor
E5790_RS13240	COG4773	Receptor
E5790_RS13250	COG1522	sequence-specific DNA binding
E5790_RS13265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5790_RS13270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5790_RS13280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E5790_RS13285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
E5790_RS13305	COG1064	alcohol dehydrogenase
E5790_RS13310	COG0583	DNA-binding transcription factor activity
E5790_RS13335	COG1902	pentaerythritol trinitrate reductase activity
E5790_RS13350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
E5790_RS13360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E5790_RS13365	COG5001	Diguanylate cyclase
E5790_RS13365	COG3706	GGDEF domain
E5790_RS13365	COG4251	negative regulation of phosphorylation
E5790_RS13365	COG2203	Gaf domain
E5790_RS13405	COG1307	EDD domain protein, DegV family
E5790_RS13415	COG0804	urea catabolic process
E5790_RS13420	COG1228	amidohydrolase
E5790_RS13440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5790_RS13460	COG0436	Aminotransferase
E5790_RS13465	COG1162	GTPase activity
E5790_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS13485	COG2851	Citrate transporter
E5790_RS13500	COG0642	Histidine kinase
E5790_RS13515	COG4191	Histidine kinase
E5790_RS13525	COG1301	dicarboxylic acid transport
E5790_RS13560	COG1560	Kdo2-lipid A biosynthetic process
E5790_RS13565	COG1519	Transferase
E5790_RS13570	COG0531	amino acid
E5790_RS13575	COG1538	Outer membrane efflux protein
E5790_RS13580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E5790_RS13590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS13595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS13610	COG0473	3-isopropylmalate dehydrogenase activity
E5790_RS13625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5790_RS13630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E5790_RS13650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
E5790_RS13655	COG0405	Gamma-glutamyltransferase
E5790_RS13660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E5790_RS13665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
E5790_RS13675	COG0745	RESPONSE REGULATOR receiver
E5790_RS13700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E5790_RS13740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
E5790_RS13765	COG0563	adenylate kinase activity
E5790_RS13770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5790_RS13780	COG0671	phosphoesterase, PA-phosphatase related
E5790_RS13800	COG3209	COG3209 Rhs family protein
E5790_RS13815	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS13830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5790_RS13835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E5790_RS13850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E5790_RS13860	COG1773	rubredoxin
E5790_RS13865	COG2912	Transglutaminase-like superfamily
E5790_RS13875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E5790_RS13885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E5790_RS13905	COG3079	Belongs to the UPF0149 family
E5790_RS13910	COG0006	proline dipeptidase activity
E5790_RS13915	COG0006	proline dipeptidase activity
E5790_RS13930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5790_RS13940	COG0346	lactoylglutathione lyase activity
E5790_RS13945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
E5790_RS13950	COG1561	YicC-like family, N-terminal region
E5790_RS13955	COG0709	Synthesizes selenophosphate from selenide and ATP
E5790_RS13965	COG3276	selenocysteine insertion sequence binding
E5790_RS13970	COG1921	L-seryl-tRNASec selenium transferase activity
E5790_RS13980	COG2864	formate dehydrogenase
E5790_RS13985	COG0437	4 iron, 4 sulfur cluster binding
E5790_RS14000	COG1758	RNA polymerase activity
E5790_RS14005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5790_RS14015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E5790_RS14025	COG0254	rRNA binding
E5790_RS14060	COG5295	Hep Hag repeat protein
E5790_RS14075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E5790_RS14105	COG0714	Associated with various cellular activities
E5790_RS14135	COG1301	dicarboxylic acid transport
E5790_RS14140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5790_RS14185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E5790_RS14200	COG0126	phosphoglycerate kinase activity
E5790_RS14210	COG0469	pyruvate kinase activity
E5790_RS14215	COG3588	fructose-bisphosphate aldolase
E5790_RS14225	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E5790_RS14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS14255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS14265	COG1115	amino acid carrier protein
E5790_RS14270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5790_RS14280	COG1115	amino acid carrier protein
E5790_RS14290	COG1970	mechanosensitive ion channel activity
E5790_RS14310	COG0471	metal ion transport
E5790_RS14310	COG3273	potassium ion transport
E5790_RS14315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E5790_RS14320	COG2022	thiamine diphosphate biosynthetic process
E5790_RS14330	COG4625	pathogenesis
E5790_RS14330	COG3240	lipase activity
E5790_RS14345	COG0189	ligase activity
E5790_RS14365	COG0745	RESPONSE REGULATOR receiver
E5790_RS14370	COG2205	protein histidine kinase activity
E5790_RS14405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E5790_RS14410	COG1459	type II secretion system
E5790_RS14440	COG0045	succinate-CoA ligase (ADP-forming) activity
E5790_RS14450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E5790_RS14450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5790_RS14460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5790_RS14465	COG0564	pseudouridine synthase activity
E5790_RS14480	COG3011	Protein conserved in bacteria
E5790_RS14485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
E5790_RS14490	COG3387	PFAM Glycoside hydrolase 15-related
E5790_RS14515	COG0028	Belongs to the TPP enzyme family
E5790_RS14535	COG0542	response to heat
E5790_RS14550	COG2205	protein histidine kinase activity
E5790_RS14555	COG0745	RESPONSE REGULATOR receiver
E5790_RS14565	COG4651	solute:proton antiporter activity
E5790_RS14565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5790_RS14585	COG0488	(ABC) transporter
E5790_RS14615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E5790_RS14635	COG0217	transcriptional regulatory protein
E5790_RS14640	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
E5790_RS14645	COG0632	four-way junction helicase activity
E5790_RS14655	COG2255	four-way junction helicase activity
E5790_RS14660	COG0824	Thioesterase
E5790_RS14665	COG0811	peptide transport
E5790_RS14680	COG0823	Involved in the tonB-independent uptake of proteins
E5790_RS14685	COG2885	chlorophyll binding
E5790_RS14695	COG0602	queuosine metabolic process
E5790_RS14700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E5790_RS14785	COG2132	Multicopper oxidase
E5790_RS14795	COG0514	ATP-dependent DNA helicase (RecQ)
E5790_RS14800	COG0783	Belongs to the Dps family
E5790_RS14805	COG1643	Atp-dependent helicase
E5790_RS14815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5790_RS14825	COG1216	Glycosyl transferase, family 2
E5790_RS14830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5790_RS14840	COG1199	ATP-dependent helicase activity
E5790_RS14845	COG1214	PFAM Peptidase M22, glycoprotease
E5790_RS14855	COG0189	ligase activity
E5790_RS14870	COG0835	chemotaxis
E5790_RS14875	COG0840	transmembrane signaling receptor activity
E5790_RS14880	COG0784	Response regulator, receiver
E5790_RS14880	COG2198	Histidine kinase
E5790_RS14880	COG0643	Histidine kinase
E5790_RS14885	COG2201	protein-glutamate methylesterase activity
E5790_RS14905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E5790_RS14915	COG0494	nUDIX hydrolase
E5790_RS14920	COG1218	3'(2'),5'-bisphosphate nucleotidase
E5790_RS14925	COG3956	TIGRFAM MazG family protein
E5790_RS14930	COG1742	UPF0060 membrane protein
E5790_RS14940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E5790_RS14945	COG0509	glycine decarboxylation via glycine cleavage system
E5790_RS14955	COG0583	DNA-binding transcription factor activity
E5790_RS15000	COG1309	transcriptional regulator
E5790_RS15005	COG4206	TonB-dependent receptor
E5790_RS15015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E5790_RS15020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5790_RS15025	COG0463	Glycosyl transferase, family 2
E5790_RS15040	COG1272	protein, Hemolysin III
E5790_RS15045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E5790_RS15050	COG0739	heme binding
E5790_RS15055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E5790_RS15060	COG0626	cystathionine gamma-synthase activity
E5790_RS15065	COG0460	homoserine dehydrogenase
E5790_RS15065	COG0527	aspartate kinase activity
E5790_RS15075	COG1760	l-serine dehydratase
E5790_RS15090	COG3038	cytochrome b561
E5790_RS15100	COG2205	protein histidine kinase activity
E5790_RS15100	COG2198	Histidine kinase
E5790_RS15100	COG0784	Response regulator, receiver
E5790_RS15110	COG0477	Major facilitator Superfamily
E5790_RS15130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E5790_RS15145	COG0259	pyridoxamine-phosphate oxidase activity
E5790_RS15155	COG3829	transcription factor binding
E5790_RS15175	COG3609	addiction module antidote protein, CC2985 family
E5790_RS15185	COG2828	Protein conserved in bacteria
E5790_RS15190	COG2079	MmgE PrpD family protein
E5790_RS15195	COG2373	Large extracellular alpha-helical protein
E5790_RS15200	COG4953	penicillin-binding protein 1C
E5790_RS15210	COG0678	peroxiredoxin activity
E5790_RS15225	COG0604	alcohol dehydrogenase
E5790_RS15230	COG0330	HflC and HflK could
E5790_RS15235	COG0330	HflC and HflK could
E5790_RS15245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
E5790_RS15255	COG0739	heme binding
E5790_RS15260	COG1376	ErfK ybiS ycfS ynhG family protein
E5790_RS15270	COG0840	transmembrane signaling receptor activity
E5790_RS15290	COG0753	catalase activity
E5790_RS15295	COG2207	Transcriptional regulator
E5790_RS15295	COG1917	Cupin 2, conserved barrel domain protein
E5790_RS15300	COG1113	amino acid transport
E5790_RS15310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5790_RS15310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5790_RS15315	COG2814	Major facilitator Superfamily
E5790_RS15350	COG0745	RESPONSE REGULATOR receiver
E5790_RS15355	COG2205	protein histidine kinase activity
E5790_RS15370	COG2879	small protein
E5790_RS15375	COG1966	Carbon starvation protein
E5790_RS15385	COG1741	Belongs to the pirin family
E5790_RS15395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E5790_RS15400	COG1741	Belongs to the pirin family
E5790_RS15420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5790_RS15425	COG0481	GTPase activity
E5790_RS15430	COG0681	Belongs to the peptidase S26 family
E5790_RS15445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E5790_RS15450	COG1381	Involved in DNA repair and RecF pathway recombination
E5790_RS15455	COG0745	RESPONSE REGULATOR receiver
E5790_RS15460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E5790_RS15465	COG2954	triphosphatase activity
E5790_RS15470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
E5790_RS15475	COG1472	Belongs to the glycosyl hydrolase 3 family
E5790_RS15480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E5790_RS15485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E5790_RS15490	COG1278	Cold shock
E5790_RS15495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5790_RS15510	COG1201	RNA secondary structure unwinding
E5790_RS15515	COG1793	dna ligase
E5790_RS15525	COG1960	acyl-CoA dehydrogenase activity
E5790_RS15540	COG0183	Belongs to the thiolase family
E5790_RS15560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5790_RS15570	COG1451	nucleotide metabolic process
E5790_RS15575	COG3122	Protein conserved in bacteria
E5790_RS15580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5790_RS15620	COG1077	Cell shape determining protein MreB Mrl
E5790_RS15625	COG2824	Alkylphosphonate utilization operon protein PhnA
E5790_RS15655	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
E5790_RS15655	COG0392	lysyltransferase activity
E5790_RS15660	COG0251	oxidation-reduction process
E5790_RS15665	COG2878	Part of a membrane complex involved in electron transport
E5790_RS15675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E5790_RS15675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E5790_RS15685	COG0346	lactoylglutathione lyase activity
E5790_RS15690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5790_RS15700	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5790_RS15725	COG4251	negative regulation of phosphorylation
E5790_RS15725	COG2203	Gaf domain
E5790_RS15725	COG3706	GGDEF domain
E5790_RS15725	COG5001	Diguanylate cyclase
E5790_RS15735	COG3118	belongs to the thioredoxin family
E5790_RS15745	COG0495	leucyl-tRNA aminoacylation
E5790_RS15760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E5790_RS15770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E5790_RS15790	COG4771	TonB-dependent receptor
E5790_RS15800	COG2968	Membrane
E5790_RS15820	COG0312	modulator of DNA gyrase
E5790_RS15825	COG3028	Belongs to the UPF0307 family
E5790_RS15830	COG0312	modulator of DNA gyrase
E5790_RS15840	COG0142	geranyltranstransferase activity
E5790_RS15845	COG1722	exodeoxyribonuclease VII activity
E5790_RS15865	COG1301	dicarboxylic acid transport
E5790_RS15870	COG0791	NLP P60 protein
E5790_RS15875	COG0791	NLP P60 protein
E5790_RS15880	COG1047	Peptidyl-prolyl cis-trans
E5790_RS15885	COG2311	Membrane
E5790_RS15900	COG0697	spore germination
E5790_RS15930	COG3590	peptidase
E5790_RS15940	COG4771	TonB-dependent receptor
E5790_RS15945	COG4771	TonB-dependent receptor
E5790_RS15950	COG0489	protein tyrosine kinase activity
E5790_RS15955	COG0717	Belongs to the dCTP deaminase family
E5790_RS15965	COG0412	Dienelactone hydrolase
E5790_RS16015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E5790_RS16025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5790_RS16030	COG0433	COG0433 Predicted ATPase
E5790_RS16045	COG0688	phosphatidylethanolamine metabolic process
E5790_RS16050	COG1999	signal sequence binding
E5790_RS16055	COG2890	protein-(glutamine-N5) methyltransferase activity
E5790_RS16060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
E5790_RS16065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5790_RS16070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5790_RS16085	COG0101	tRNA pseudouridine synthase activity
E5790_RS16090	COG0135	phosphoribosylanthranilate isomerase activity
E5790_RS16125	COG0133	tryptophan synthase activity
E5790_RS16135	COG0159	tryptophan synthase activity
E5790_RS16140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E5790_RS16145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E5790_RS16150	COG0726	polysaccharide deacetylase
E5790_RS16155	COG0438	transferase activity, transferring glycosyl groups
E5790_RS16160	COG3119	arylsulfatase activity
E5790_RS16170	COG0149	triose-phosphate isomerase activity
E5790_RS16185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5790_RS16190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5790_RS16195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5790_RS16200	COG0649	NAD binding
E5790_RS16205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E5790_RS16220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E5790_RS16225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5790_RS16235	COG0713	ATP synthesis coupled electron transport
E5790_RS16250	COG1007	ATP synthesis coupled electron transport
E5790_RS16265	COG0779	Required for maturation of 30S ribosomal subunits
E5790_RS16270	COG0195	Participates in both transcription termination and antitermination
E5790_RS16275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
E5790_RS16280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E5790_RS16290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E5790_RS16295	COG1185	polyribonucleotide nucleotidyltransferase activity
E5790_RS16325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E5790_RS16330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E5790_RS16335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E5790_RS16340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E5790_RS16345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E5790_RS16350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E5790_RS16350	COG0072	phenylalanine-tRNA ligase activity
E5790_RS16355	COG0776	regulation of translation
E5790_RS16395	COG1794	racemase activity, acting on amino acids and derivatives
E5790_RS16400	COG1280	lysine exporter protein (LysE YggA)
E5790_RS16405	COG5487	UPF0391 membrane protein
E5790_RS16410	COG2076	Multidrug Resistance protein
E5790_RS16415	COG1309	transcriptional regulator
E5790_RS16445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E5790_RS16455	COG1960	acyl-CoA dehydrogenase activity
E5790_RS16480	COG2130	NADP-dependent
E5790_RS16485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E5790_RS16485	COG2169	Transcriptional regulator
E5790_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS16505	COG4771	TonB-dependent receptor
E5790_RS16520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E5790_RS16530	COG1570	exodeoxyribonuclease VII activity
E5790_RS16535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E5790_RS16540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E5790_RS16540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E5790_RS16545	COG0802	atpase or kinase
E5790_RS16550	COG0860	N-Acetylmuramoyl-L-alanine amidase
E5790_RS16555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E5790_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS16585	COG0501	Belongs to the peptidase M48B family
E5790_RS16605	COG3300	MHYT domain
E5790_RS16605	COG5001	Diguanylate cyclase
E5790_RS16610	COG1509	lysine 2,3-aminomutase activity
E5790_RS16615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E5790_RS16620	COG0402	S-adenosylhomocysteine deaminase activity
E5790_RS16625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5790_RS16645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E5790_RS16665	COG2166	iron-sulfur cluster assembly
E5790_RS16680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E5790_RS16685	COG0137	argininosuccinate synthase activity
E5790_RS16690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5790_RS16695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E5790_RS16705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E5790_RS16710	COG0165	Argininosuccinate lyase
E5790_RS16735	COG1215	transferase activity, transferring glycosyl groups
E5790_RS16740	COG1649	PFAM Uncharacterised BCR, COG1649
E5790_RS16740	COG0726	polysaccharide deacetylase
E5790_RS16770	COG1294	oxidase, subunit
E5790_RS16780	COG4988	ABC transporter
E5790_RS16785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E5790_RS16795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E5790_RS16805	COG3088	subunit of a heme lyase
E5790_RS16805	COG4235	cytochrome complex assembly
E5790_RS16820	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
E5790_RS16840	COG4133	protoheme IX ABC transporter activity
E5790_RS16845	COG0436	Aminotransferase
E5790_RS16860	COG2814	Major facilitator Superfamily
E5790_RS16870	COG1187	pseudouridine synthase activity
E5790_RS16875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E5790_RS16880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E5790_RS16885	COG2350	Protein conserved in bacteria
E5790_RS16890	COG0271	Belongs to the BolA IbaG family
E5790_RS16920	COG0395	ABC-type sugar transport system, permease component
E5790_RS16935	COG1530	ribonuclease E activity
E5790_RS16945	COG0428	transporter
E5790_RS16955	COG2154	pterin-4-alpha-carbinolamine dehydratase
E5790_RS16960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E5790_RS16960	COG0316	Belongs to the HesB IscA family
E5790_RS16975	COG4290	ribonuclease
E5790_RS16980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E5790_RS16990	COG3104	oligopeptide transport
E5790_RS16995	COG0705	Rhomboid family
E5790_RS17010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5790_RS17015	COG0339	signal peptide processing
E5790_RS17020	COG0386	Belongs to the glutathione peroxidase family
E5790_RS17035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5790_RS17040	COG1595	DNA-templated transcription, initiation
E5790_RS17055	COG0625	glutathione transferase activity
E5790_RS17090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E5790_RS17095	COG0084	hydrolase, TatD family'
E5790_RS17115	COG0625	glutathione transferase activity
E5790_RS17125	COG0367	asparagine synthase
E5790_RS17135	COG0305	Participates in initiation and elongation during chromosome replication
E5790_RS17145	COG3540	Alkaline phosphatase
E5790_RS17170	COG0567	Dehydrogenase, E1 component
E5790_RS17180	COG2850	peptidyl-arginine hydroxylation
E5790_RS17215	COG1131	(ABC) transporter
E5790_RS17220	COG1725	Transcriptional regulator
E5790_RS17230	COG0386	Belongs to the glutathione peroxidase family
E5790_RS17245	COG2900	Belongs to the SlyX family
E5790_RS17255	COG2755	lipolytic protein G-D-S-L family
E5790_RS17255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
E5790_RS17265	COG0646	methionine synthase
E5790_RS17265	COG1410	methionine synthase
E5790_RS17280	COG1960	acyl-CoA dehydrogenase activity
E5790_RS17290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS17295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS17305	COG2902	Dehydrogenase
E5790_RS17325	COG0667	Aldo Keto reductase
E5790_RS17335	COG2925	Exonuclease
E5790_RS17340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5790_RS17345	COG3844	kynureninase activity
E5790_RS17355	COG0288	reversible hydration of carbon dioxide
E5790_RS17375	COG0017	Asparaginyl-tRNA synthetase
E5790_RS17380	COG0316	Belongs to the HesB IscA family
E5790_RS17390	COG0360	Binds together with S18 to 16S ribosomal RNA
E5790_RS17395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E5790_RS17400	COG0359	binds to the 23S rRNA
E5790_RS17415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E5790_RS17420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E5790_RS17430	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
E5790_RS17440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
E5790_RS17450	COG4993	Dehydrogenase
E5790_RS17570	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E5790_RS17585	COG1228	amidohydrolase
E5790_RS17630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
E5790_RS17635	COG1605	Chorismate mutase
E5790_RS17635	COG0077	Prephenate dehydratase
E5790_RS17640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E5790_RS17655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E5790_RS17665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E5790_RS17670	COG0583	DNA-binding transcription factor activity
E5790_RS17690	COG0210	DNA helicase
E5790_RS17695	COG0604	alcohol dehydrogenase
E5790_RS17700	COG1733	regulation of RNA biosynthetic process
E5790_RS17725	COG4774	siderophore transport
E5790_RS17740	COG4191	Histidine kinase
E5790_RS17740	COG0784	Response regulator, receiver
E5790_RS17780	COG2814	Major facilitator Superfamily
E5790_RS17805	COG3736	Type IV secretory pathway, component VirB8
E5790_RS17815	COG2948	multi-organism process
E5790_RS17835	COG3702	type iv secretory pathway
E5790_RS17935	COG0456	acetyltransferase
E5790_RS17940	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5790_RS17945	COG1733	regulation of RNA biosynthetic process
E5790_RS17955	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E5790_RS17965	COG1902	pentaerythritol trinitrate reductase activity
E5790_RS17970	COG0668	transmembrane transport
E5790_RS17980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
E5790_RS18000	COG0534	Mate efflux family protein
E5790_RS18015	COG3243	poly(R)-hydroxyalkanoic acid synthase
E5790_RS18025	COG1983	PspC domain protein
E5790_RS18040	COG2183	response to ionizing radiation
E5790_RS18045	COG5002	protein histidine kinase activity
E5790_RS18045	COG5001	Diguanylate cyclase
E5790_RS18045	COG3447	MASE1 domain protein
E5790_RS18145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5790_RS18160	COG0531	amino acid
E5790_RS18190	COG4206	TonB-dependent receptor
E5790_RS18190	COG1629	transport
E5790_RS18200	COG1595	DNA-templated transcription, initiation
E5790_RS18215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E5790_RS18215	COG0519	Catalyzes the synthesis of GMP from XMP
E5790_RS18220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5790_RS18235	COG0587	DNA-directed DNA polymerase activity
E5790_RS18290	COG2814	Major facilitator Superfamily
E5790_RS18315	COG1285	pathogenesis
E5790_RS18325	COG2186	Transcriptional regulator
E5790_RS18330	COG1304	FMN binding
E5790_RS18335	COG0277	FAD linked oxidase domain protein
E5790_RS18370	COG3161	chorismate lyase activity
E5790_RS18385	COG0583	DNA-binding transcription factor activity
E5790_RS18395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E5790_RS18405	COG2814	Major facilitator Superfamily
E5790_RS18410	COG2197	response regulator
E5790_RS18415	COG3850	Histidine kinase
E5790_RS18430	COG1335	isochorismatase
E5790_RS18440	COG1228	amidohydrolase
E5790_RS18450	COG2814	Major facilitator Superfamily
E5790_RS18505	COG4964	Belongs to the GSP D family
E5790_RS18550	COG2226	methyltransferase
E5790_RS18570	COG4772	TonB-dependent receptor
E5790_RS18580	COG0583	DNA-binding transcription factor activity
E5790_RS18600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E5790_RS18605	COG4206	TonB-dependent receptor
E5790_RS18615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E5790_RS18620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E5790_RS18635	COG1914	H( )-stimulated, divalent metal cation uptake system
E5790_RS18695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5790_RS18700	COG2409	Drug exporters of the RND superfamily
E5790_RS18715	COG1021	2,3-dihydroxybenzoate-AMP ligase
E5790_RS18720	COG1535	isochorismatase
E5790_RS18720	COG3433	isochorismatase activity
E5790_RS18730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E5790_RS18730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E5790_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS18750	COG2885	chlorophyll binding
E5790_RS18770	COG2194	sulfuric ester hydrolase activity
E5790_RS18780	COG2205	protein histidine kinase activity
E5790_RS18825	COG1566	PFAM secretion protein HlyD family protein
E5790_RS18840	COG2207	Transcriptional regulator
E5790_RS18895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E5790_RS18900	COG0315	cyclic pyranopterin monophosphate synthase activity
E5790_RS18900	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5790_RS18905	COG0303	'Molybdopterin
E5790_RS18915	COG0314	molybdopterin synthase activity
E5790_RS18920	COG0746	molybdenum cofactor guanylyltransferase activity
E5790_RS18930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5790_RS18935	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5790_RS18940	COG4149	molybdate abc transporter
E5790_RS18945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E5790_RS18955	COG0840	transmembrane signaling receptor activity
E5790_RS18965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5790_RS18970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5790_RS19110	COG0811	peptide transport
E5790_RS19140	COG1335	isochorismatase
E5790_RS19145	COG1335	isochorismatase
E5790_RS19190	COG3920	Histidine kinase
E5790_RS19205	COG0477	Major facilitator Superfamily
E5790_RS19225	COG3537	Alpha-1,2-mannosidase
E5790_RS19230	COG0642	Histidine kinase
E5790_RS19260	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS19265	COG0583	DNA-binding transcription factor activity
E5790_RS19270	COG5002	protein histidine kinase activity
E5790_RS19305	COG0656	L-ascorbic acid biosynthetic process
E5790_RS19310	COG0583	DNA-binding transcription factor activity
E5790_RS19325	COG1136	(ABC) transporter
E5790_RS19350	COG0477	Major facilitator Superfamily
E5790_RS19375	COG0243	molybdopterin cofactor binding
E5790_RS19435	COG4566	intracellular signal transduction
E5790_RS19440	COG4191	Histidine kinase
E5790_RS19445	COG1285	pathogenesis
E5790_RS19450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E5790_RS19475	COG3188	usher protein
E5790_RS19500	COG4774	siderophore transport
E5790_RS19510	COG3214	Protein conserved in bacteria
E5790_RS19520	COG2205	protein histidine kinase activity
E5790_RS19525	COG0745	RESPONSE REGULATOR receiver
E5790_RS19540	COG0577	efflux transmembrane transporter activity
E5790_RS19540	COG1136	(ABC) transporter
E5790_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
E5790_RS19560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5790_RS19565	COG0366	Alpha amylase catalytic
E5790_RS19570	COG0708	Exodeoxyribonuclease III
E5790_RS19700	COG2204	response regulator
E5790_RS19725	COG0583	DNA-binding transcription factor activity
E5790_RS19745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5790_RS19810	COG0583	DNA-binding transcription factor activity
E5790_RS19815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E5790_RS19840	COG0583	DNA-binding transcription factor activity
E5790_RS19845	COG2828	Protein conserved in bacteria
E5790_RS19860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E5790_RS19905	COG1070	Carbohydrate kinase
E5790_RS19915	COG0477	Major facilitator Superfamily
E5790_RS19920	COG1472	Belongs to the glycosyl hydrolase 3 family
E5790_RS19930	COG3661	Belongs to the glycosyl hydrolase 67 family
E5790_RS19940	COG3507	Belongs to the glycosyl hydrolase 43 family
E5790_RS19945	COG1472	Belongs to the glycosyl hydrolase 3 family
E5790_RS19950	COG2211	Major facilitator Superfamily
E5790_RS19970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5790_RS19970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5790_RS19975	COG1105	Belongs to the carbohydrate kinase PfkB family
E5790_RS19980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5790_RS19980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5790_RS19985	COG1609	Transcriptional regulator
E5790_RS20020	COG1063	alcohol dehydrogenase
E5790_RS20040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E5790_RS20070	COG3685	Protein conserved in bacteria
E5790_RS20075	COG3546	catalase activity
E5790_RS20100	COG3685	Protein conserved in bacteria
E5790_RS20145	COG4221	oxidoreductase activity
E5790_RS20150	COG4977	sequence-specific DNA binding
E5790_RS20165	COG1309	transcriptional regulator
E5790_RS20180	COG2080	2 iron, 2 sulfur cluster binding
E5790_RS20185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E5790_RS20190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E5790_RS20195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E5790_RS20230	COG0653	protein targeting
E5790_RS20330	COG1309	transcriptional regulator
E5790_RS20345	COG1902	pentaerythritol trinitrate reductase activity
E5790_RS20360	COG0583	DNA-binding transcription factor activity
E5790_RS20390	COG4644	lycopene metabolic process
E5790_RS20445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E5790_RS20470	COG2132	Multicopper oxidase
E5790_RS20525	COG0010	Belongs to the arginase family
E5790_RS20540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS20545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS20560	COG2217	Heavy metal translocating P-type atpase
E5790_RS20605	COG4644	lycopene metabolic process
E5790_RS20610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5790_RS20625	COG0789	Transcriptional regulator
E5790_RS20635	COG2608	mercury ion transmembrane transporter activity
E5790_RS20640	COG2608	mercury ion transmembrane transporter activity
E5790_RS20645	COG0789	Transcriptional regulator
E5790_RS20745	COG1294	oxidase, subunit
E5790_RS20750	COG1271	oxidase subunit
E5790_RS20755	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E5790_RS20760	COG0243	molybdopterin cofactor binding
E5790_RS20765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E5790_RS20770	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5790_RS20770	COG0315	cyclic pyranopterin monophosphate synthase activity
E5790_RS20775	COG0303	'Molybdopterin
E5790_RS20785	COG0314	molybdopterin synthase activity
E5790_RS20790	COG0746	molybdenum cofactor guanylyltransferase activity
E5790_RS20800	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5790_RS20805	COG4149	molybdate abc transporter
E5790_RS20810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E5790_RS20815	COG2204	response regulator
E5790_RS20820	COG4191	Histidine kinase
E5790_RS20825	COG3781	membrane
E5790_RS20830	COG0556	nucleotide-excision repair
E5790_RS20850	COG1252	NADH dehydrogenase
E5790_RS20855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5790_RS20885	COG1252	NADH dehydrogenase
E5790_RS20890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
E5790_RS20970	COG0789	Transcriptional regulator
E5790_RS21015	COG2205	protein histidine kinase activity
E5790_RS21030	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
E5790_RS21040	COG4251	negative regulation of phosphorylation
E5790_RS21045	COG0784	Response regulator, receiver
E5790_RS21055	COG0702	epimerase
E5790_RS21065	COG1595	DNA-templated transcription, initiation
E5790_RS21080	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
E5790_RS21090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5790_RS21125	COG5002	protein histidine kinase activity
E5790_RS21125	COG0784	Response regulator, receiver
E5790_RS21140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E5790_RS21150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E5790_RS21155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5790_RS21160	COG4558	Periplasmic binding protein
E5790_RS21170	COG2819	hydrolase of the alpha beta superfamily
E5790_RS21180	COG3152	Membrane
E5790_RS21185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5790_RS21200	COG1674	ftsk spoiiie
E5790_RS21205	COG0492	ferredoxin-NADP+ reductase activity
E5790_RS21240	COG0542	response to heat
E5790_RS21250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
E5790_RS21265	COG0482	sulfurtransferase activity
E5790_RS21270	COG2915	High frequency lysogenization protein hflD homolog
E5790_RS21305	COG5002	protein histidine kinase activity
E5790_RS21325	COG0835	chemotaxis
E5790_RS21325	COG0784	Response regulator, receiver
E5790_RS21330	COG1815	bacterial-type flagellum-dependent cell motility
E5790_RS21350	COG4787	bacterial-type flagellum-dependent cell motility
E5790_RS21360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E5790_RS21375	COG1256	bacterial-type flagellum assembly
E5790_RS21400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
E5790_RS21420	COG2197	response regulator
E5790_RS21445	COG1677	Flagellar hook-basal body complex protein FliE
E5790_RS21495	COG3190	flagellar
E5790_RS21505	COG1987	bacterial-type flagellum assembly
E5790_RS21520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E5790_RS21525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E5790_RS21550	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
E5790_RS21555	COG0643	Histidine kinase
E5790_RS21555	COG2198	Histidine kinase
E5790_RS21555	COG0784	Response regulator, receiver
E5790_RS21560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E5790_RS21565	COG1360	Flagellar Motor Protein
E5790_RS21575	COG0835	chemotaxis
E5790_RS21585	COG0745	RESPONSE REGULATOR receiver
E5790_RS21595	COG0840	transmembrane signaling receptor activity
E5790_RS21600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
E5790_RS21605	COG0835	chemotaxis
E5790_RS21615	COG0840	transmembrane signaling receptor activity
E5790_RS21620	COG0840	transmembrane signaling receptor activity
E5790_RS21630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
E5790_RS21670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E5790_RS21675	COG1309	transcriptional regulator
E5790_RS21680	COG1012	belongs to the aldehyde dehydrogenase family
E5790_RS21685	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
E5790_RS21690	COG0318	PFAM AMP-dependent synthetase and ligase
E5790_RS21695	COG1024	Enoyl-CoA hydratase
E5790_RS21700	COG0784	Response regulator, receiver
E5790_RS21700	COG2198	Histidine kinase
E5790_RS21700	COG2205	protein histidine kinase activity
E5790_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
E5790_RS21735	COG3279	Response regulator of the LytR AlgR family
E5790_RS21745	COG4676	Protein conserved in bacteria
E5790_RS21750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E5790_RS21765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5790_RS21770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E5790_RS21775	COG0505	Belongs to the CarA family
E5790_RS21780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E5790_RS21795	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5790_RS21840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E5790_RS21855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5790_RS21860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5790_RS21865	COG0745	RESPONSE REGULATOR receiver
E5790_RS21870	COG2205	protein histidine kinase activity