locus-tag	class	description
FQS62_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FQS62_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FQS62_RS00020	COG0187	DNA topoisomerase II activity
FQS62_RS00025	COG1266	CAAX protease self-immunity
FQS62_RS00030	COG0501	Belongs to the peptidase M48B family
FQS62_RS00105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FQS62_RS00125	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS00170	COG3422	double-strand break repair
FQS62_RS00180	COG0659	secondary active sulfate transmembrane transporter activity
FQS62_RS00195	COG0798	PFAM Bile acid sodium symporter
FQS62_RS00210	COG0431	NADPH-dependent FMN reductase
FQS62_RS00235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQS62_RS00250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQS62_RS00250	COG3453	Protein conserved in bacteria
FQS62_RS00270	COG0640	Transcriptional regulator
FQS62_RS00305	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FQS62_RS00350	COG0800	Aldolase
FQS62_RS00365	COG3186	Phenylalanine-4-hydroxylase
FQS62_RS00370	COG1522	sequence-specific DNA binding
FQS62_RS00380	COG1752	Esterase of the alpha-beta hydrolase superfamily
FQS62_RS00390	COG4771	TonB-dependent receptor
FQS62_RS00410	COG1122	ATPase activity
FQS62_RS00430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FQS62_RS00435	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FQS62_RS00445	COG0210	DNA helicase
FQS62_RS00455	COG3132	Protein of unknown function, DUF480
FQS62_RS00460	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FQS62_RS00465	COG0284	orotidine-5'-phosphate decarboxylase activity
FQS62_RS00475	COG2937	Belongs to the GPAT DAPAT family
FQS62_RS00485	COG0037	tRNA processing
FQS62_RS00490	COG2974	May be involved in recombination
FQS62_RS00500	COG1803	Methylglyoxal synthase
FQS62_RS00505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQS62_RS00505	COG2205	protein histidine kinase activity
FQS62_RS00510	COG0493	'glutamate synthase
FQS62_RS00515	COG0070	glutamate synthase
FQS62_RS00515	COG0067	glutamate synthase
FQS62_RS00515	COG0069	glutamate synthase activity
FQS62_RS00535	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS00540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQS62_RS00565	COG1205	dead DEAH box helicase
FQS62_RS00565	COG1111	helicase
FQS62_RS00605	COG0714	Associated with various cellular activities
FQS62_RS00625	COG0312	modulator of DNA gyrase
FQS62_RS00645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQS62_RS00665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FQS62_RS00690	COG1881	PFAM PEBP family protein
FQS62_RS00700	COG1968	undecaprenyl-diphosphatase activity
FQS62_RS00705	COG0174	glutamine synthetase
FQS62_RS00710	COG0347	Belongs to the P(II) protein family
FQS62_RS00715	COG0004	ammonium transporteR
FQS62_RS00730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FQS62_RS00740	COG3852	Histidine kinase
FQS62_RS00745	COG2204	response regulator
FQS62_RS00750	COG2032	superoxide dismutase activity
FQS62_RS00755	COG2032	superoxide dismutase activity
FQS62_RS00765	COG0183	Belongs to the thiolase family
FQS62_RS00800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FQS62_RS00805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FQS62_RS00825	COG0798	PFAM Bile acid sodium symporter
FQS62_RS00840	COG0431	NADPH-dependent FMN reductase
FQS62_RS00885	COG2837	iron assimilation
FQS62_RS00925	COG2197	response regulator
FQS62_RS00930	COG2205	protein histidine kinase activity
FQS62_RS00930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQS62_RS00935	COG3474	cytochrome
FQS62_RS00945	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS00950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FQS62_RS00960	COG0612	Peptidase, M16
FQS62_RS00970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQS62_RS00975	COG0596	Alpha beta hydrolase
FQS62_RS00985	COG0318	PFAM AMP-dependent synthetase and ligase
FQS62_RS00990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQS62_RS01000	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQS62_RS01010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FQS62_RS01040	COG0339	signal peptide processing
FQS62_RS01045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FQS62_RS01055	COG0681	Belongs to the peptidase S26 family
FQS62_RS01060	COG2814	Major facilitator Superfamily
FQS62_RS01065	COG0583	DNA-binding transcription factor activity
FQS62_RS01070	COG0583	DNA-binding transcription factor activity
FQS62_RS01075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FQS62_RS01080	COG2224	Isocitrate lyase
FQS62_RS01085	COG3706	GGDEF domain
FQS62_RS01110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQS62_RS01115	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS01135	COG0697	spore germination
FQS62_RS01145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FQS62_RS01160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQS62_RS01165	COG1280	lysine exporter protein (LysE YggA)
FQS62_RS01170	COG1607	acyl-coa hydrolase
FQS62_RS01180	COG1902	pentaerythritol trinitrate reductase activity
FQS62_RS01195	COG1335	isochorismatase
FQS62_RS01200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FQS62_RS01210	COG1056	cytidyltransferase-related domain
FQS62_RS01210	COG1051	belongs to the nudix hydrolase family
FQS62_RS01215	COG1752	Esterase of the alpha-beta hydrolase superfamily
FQS62_RS01220	COG1396	sequence-specific DNA binding
FQS62_RS01220	COG3800	Transcriptional regulator
FQS62_RS01230	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS01235	COG1024	Enoyl-CoA hydratase
FQS62_RS01240	COG1024	Enoyl-CoA hydratase
FQS62_RS01250	COG1764	response to oxidative stress
FQS62_RS01265	COG3657	addiction module killer protein
FQS62_RS01290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FQS62_RS01310	COG3228	Belongs to the MtfA family
FQS62_RS01320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FQS62_RS01320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FQS62_RS01325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FQS62_RS01385	COG3237	CsbD-like
FQS62_RS01395	COG0180	Tryptophanyl-tRNA synthetase
FQS62_RS01420	COG0477	Major facilitator Superfamily
FQS62_RS01425	COG0697	spore germination
FQS62_RS01440	COG0577	efflux transmembrane transporter activity
FQS62_RS01440	COG1136	(ABC) transporter
FQS62_RS01450	COG1136	(ABC) transporter
FQS62_RS01455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS01470	COG4585	Histidine kinase
FQS62_RS01475	COG2197	response regulator
FQS62_RS01490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FQS62_RS01500	COG0628	permease
FQS62_RS01520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQS62_RS01535	COG5507	3-demethylubiquinone-9 3-methyltransferase
FQS62_RS01565	COG2814	Major facilitator Superfamily
FQS62_RS01570	COG0583	DNA-binding transcription factor activity
FQS62_RS01575	COG4807	Protein conserved in bacteria
FQS62_RS01580	COG4221	oxidoreductase activity
FQS62_RS01590	COG0018	arginyl-trna synthetase
FQS62_RS01595	COG2003	Belongs to the UPF0758 family
FQS62_RS01600	COG2197	response regulator
FQS62_RS01605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FQS62_RS01625	COG2205	protein histidine kinase activity
FQS62_RS01635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FQS62_RS01640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FQS62_RS01655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FQS62_RS01665	COG2223	nitrite transmembrane transporter activity
FQS62_RS01680	COG0739	heme binding
FQS62_RS01685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FQS62_RS01745	COG2234	aminopeptidase activity
FQS62_RS01755	COG4942	peptidase
FQS62_RS01760	COG0793	Belongs to the peptidase S41A family
FQS62_RS01770	COG2067	long-chain fatty acid transport protein
FQS62_RS01795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FQS62_RS01840	COG0109	protoheme IX farnesyltransferase activity
FQS62_RS01860	COG0358	DNA primase activity
FQS62_RS01865	COG1295	ribonuclease BN
FQS62_RS01880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FQS62_RS01890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FQS62_RS01895	COG0668	transmembrane transport
FQS62_RS01910	COG2133	pyrroloquinoline quinone binding
FQS62_RS01915	COG4682	membrane
FQS62_RS01925	COG0531	amino acid
FQS62_RS01935	COG1737	Transcriptional regulator
FQS62_RS01940	COG4948	Mandelate Racemase Muconate Lactonizing
FQS62_RS01960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQS62_RS01990	COG5383	Protein conserved in bacteria
FQS62_RS02000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FQS62_RS02005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FQS62_RS02035	COG0778	Nitroreductase
FQS62_RS02040	COG2353	YceI-like domain
FQS62_RS02055	COG2375	cellular response to nickel ion
FQS62_RS02075	COG1204	response to ionizing radiation
FQS62_RS02155	COG2267	carboxylic ester hydrolase activity
FQS62_RS02220	COG0488	(ABC) transporter
FQS62_RS02225	COG0583	DNA-binding transcription factor activity
FQS62_RS02235	COG2814	Major facilitator Superfamily
FQS62_RS02240	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FQS62_RS02245	COG1113	amino acid transport
FQS62_RS02250	COG0741	lytic transglycosylase activity
FQS62_RS02275	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FQS62_RS02290	COG4941	Belongs to the sigma-70 factor family
FQS62_RS02320	COG3275	phosphorelay sensor kinase activity
FQS62_RS02325	COG3279	Response regulator of the LytR AlgR family
FQS62_RS02345	COG1309	transcriptional regulator
FQS62_RS02355	COG2814	Major facilitator Superfamily
FQS62_RS02360	COG3590	peptidase
FQS62_RS02365	COG5001	Diguanylate cyclase
FQS62_RS02370	COG0583	DNA-binding transcription factor activity
FQS62_RS02380	COG3384	dioxygenase
FQS62_RS02385	COG0025	NhaP-type Na H and K H
FQS62_RS02410	COG1360	Flagellar Motor Protein
FQS62_RS02440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQS62_RS02455	COG2205	protein histidine kinase activity
FQS62_RS02455	COG0784	Response regulator, receiver
FQS62_RS02470	COG2813	Specifically methylates the guanine in position
FQS62_RS02475	COG1187	pseudouridine synthase activity
FQS62_RS02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQS62_RS02490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FQS62_RS02495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FQS62_RS02510	COG0583	DNA-binding transcription factor activity
FQS62_RS02515	COG2226	methyltransferase
FQS62_RS02540	COG1956	GAF domain-containing protein
FQS62_RS02545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FQS62_RS02550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQS62_RS02555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FQS62_RS02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FQS62_RS02560	COG0785	Cytochrome C biogenesis protein
FQS62_RS02565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FQS62_RS02575	COG5002	protein histidine kinase activity
FQS62_RS02585	COG0745	RESPONSE REGULATOR receiver
FQS62_RS02590	COG0367	asparagine synthase
FQS62_RS02600	COG0720	synthase
FQS62_RS02635	COG0625	glutathione transferase activity
FQS62_RS02640	COG1573	uracil-dna glycosylase
FQS62_RS02675	COG0626	cystathionine gamma-synthase activity
FQS62_RS02690	COG0110	maltose O-acetyltransferase activity
FQS62_RS02695	COG1216	Glycosyl transferase, family 2
FQS62_RS02695	COG0438	transferase activity, transferring glycosyl groups
FQS62_RS02700	COG3754	Rhamnan synthesis protein F
FQS62_RS02710	COG2226	methyltransferase
FQS62_RS02740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQS62_RS02745	COG0300	oxidoreductase activity
FQS62_RS02755	COG0546	phosphoglycolate phosphatase activity
FQS62_RS02755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FQS62_RS02770	COG2076	Multidrug Resistance protein
FQS62_RS02790	COG0463	Glycosyl transferase, family 2
FQS62_RS02805	COG2086	electron transfer activity
FQS62_RS02840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQS62_RS02845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FQS62_RS02880	COG1127	ABC transporter
FQS62_RS02885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FQS62_RS02900	COG0442	prolyl-tRNA aminoacylation
FQS62_RS02910	COG1183	phosphatidylcholine synthase activity
FQS62_RS02920	COG0456	acetyltransferase
FQS62_RS02930	COG0525	valine-tRNA ligase activity
FQS62_RS02940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FQS62_RS02950	COG0795	lipopolysaccharide-transporting ATPase activity
FQS62_RS02960	COG4974	Belongs to the 'phage' integrase family
FQS62_RS02965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQS62_RS02980	COG5295	Hep Hag repeat protein
FQS62_RS02985	COG1404	Belongs to the peptidase S8 family
FQS62_RS02990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FQS62_RS02995	COG1459	type II secretion system
FQS62_RS03000	COG2165	general secretion pathway protein
FQS62_RS03005	COG4970	Tfp pilus assembly protein FimT
FQS62_RS03010	COG2165	general secretion pathway protein
FQS62_RS03015	COG4795	General secretion pathway protein
FQS62_RS03020	COG3156	type II secretion system protein K
FQS62_RS03025	COG3166	PFAM Fimbrial assembly family protein
FQS62_RS03040	COG1450	Type ii and iii secretion system protein
FQS62_RS03065	COG3539	Fimbrial protein
FQS62_RS03085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FQS62_RS03095	COG1215	transferase activity, transferring glycosyl groups
FQS62_RS03110	COG2252	PERMEase
FQS62_RS03115	COG0488	(ABC) transporter
FQS62_RS03125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FQS62_RS03140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FQS62_RS03145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQS62_RS03145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQS62_RS03180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FQS62_RS03185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FQS62_RS03235	COG3121	Chaperone
FQS62_RS03270	COG0488	(ABC) transporter
FQS62_RS03275	COG0277	FAD linked oxidase domain protein
FQS62_RS03280	COG1988	membrane-bound metal-dependent
FQS62_RS03315	COG2001	Belongs to the MraZ family
FQS62_RS03320	COG0275	rRNA processing
FQS62_RS03325	COG3116	cell division
FQS62_RS03335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FQS62_RS03340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FQS62_RS03355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FQS62_RS03360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FQS62_RS03365	COG1181	Belongs to the D-alanine--D-alanine ligase family
FQS62_RS03370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FQS62_RS03380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FQS62_RS03385	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FQS62_RS03395	COG0739	heme binding
FQS62_RS03400	COG0653	protein targeting
FQS62_RS03415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FQS62_RS03425	COG3275	phosphorelay sensor kinase activity
FQS62_RS03435	COG0402	S-adenosylhomocysteine deaminase activity
FQS62_RS03455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FQS62_RS03460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FQS62_RS03470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FQS62_RS03475	COG1607	acyl-coa hydrolase
FQS62_RS03480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FQS62_RS03500	COG4106	trans-aconitate 2-methyltransferase activity
FQS62_RS03505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FQS62_RS03515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQS62_RS03520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FQS62_RS03525	COG0667	Aldo Keto reductase
FQS62_RS03535	COG4771	TonB-dependent receptor
FQS62_RS03550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FQS62_RS03555	COG4181	ATPase activity
FQS62_RS03570	COG0642	Histidine kinase
FQS62_RS03580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FQS62_RS03585	COG0861	Integral membrane protein TerC family
FQS62_RS03590	COG2814	Major facilitator Superfamily
FQS62_RS03595	COG1704	LemA family
FQS62_RS03610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FQS62_RS03615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FQS62_RS03630	COG3738	Protein conserved in bacteria
FQS62_RS03635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FQS62_RS03640	COG2967	ApaG domain
FQS62_RS03650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FQS62_RS03655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FQS62_RS03660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FQS62_RS03670	COG2096	Adenosyltransferase
FQS62_RS03680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQS62_RS03685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQS62_RS03690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FQS62_RS03695	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FQS62_RS03715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQS62_RS03725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FQS62_RS03735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FQS62_RS03740	COG0583	DNA-binding transcription factor activity
FQS62_RS03745	COG3634	alkyl hydroperoxide reductase activity
FQS62_RS03800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FQS62_RS03825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FQS62_RS03840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FQS62_RS03845	COG1404	Belongs to the peptidase S8 family
FQS62_RS03865	COG1295	ribonuclease BN
FQS62_RS03870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FQS62_RS03885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FQS62_RS03890	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FQS62_RS03905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FQS62_RS03915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FQS62_RS03920	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FQS62_RS03925	COG0193	aminoacyl-tRNA hydrolase activity
FQS62_RS03930	COG0012	GTP binding
FQS62_RS03935	COG4206	TonB-dependent receptor
FQS62_RS03940	COG4242	Belongs to the peptidase S51 family
FQS62_RS03965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQS62_RS03980	COG0250	Participates in transcription elongation, termination and antitermination
FQS62_RS03985	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FQS62_RS03990	COG0081	regulation of translation
FQS62_RS03995	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FQS62_RS04000	COG0222	ribosome binding
FQS62_RS04005	COG0085	RNA polymerase activity
FQS62_RS04010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FQS62_RS04015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FQS62_RS04020	COG0049	tRNA binding
FQS62_RS04025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FQS62_RS04030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQS62_RS04035	COG0051	transcription antitermination factor activity, RNA binding
FQS62_RS04040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FQS62_RS04045	COG0088	Forms part of the polypeptide exit tunnel
FQS62_RS04050	COG0089	rRNA binding
FQS62_RS04055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FQS62_RS04060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FQS62_RS04065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FQS62_RS04070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FQS62_RS04075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FQS62_RS04080	COG0255	Belongs to the universal ribosomal protein uL29 family
FQS62_RS04085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FQS62_RS04090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FQS62_RS04095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FQS62_RS04100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FQS62_RS04105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FQS62_RS04110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FQS62_RS04115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FQS62_RS04120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FQS62_RS04125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FQS62_RS04130	COG1841	ribosomal large subunit assembly
FQS62_RS04135	COG0200	Binds to the 23S rRNA
FQS62_RS04140	COG0201	protein transport
FQS62_RS04145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FQS62_RS04150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FQS62_RS04155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FQS62_RS04160	COG0202	RNA polymerase activity
FQS62_RS04165	COG0203	ribosomal protein L17
FQS62_RS04180	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FQS62_RS04190	COG0154	amidase activity
FQS62_RS04205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FQS62_RS04210	COG0039	L-malate dehydrogenase activity
FQS62_RS04215	COG0564	pseudouridine synthase activity
FQS62_RS04220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQS62_RS04245	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQS62_RS04245	COG1902	pentaerythritol trinitrate reductase activity
FQS62_RS04250	COG2364	Membrane
FQS62_RS04270	COG1187	pseudouridine synthase activity
FQS62_RS04290	COG1063	alcohol dehydrogenase
FQS62_RS04300	COG0588	phosphoglycerate mutase activity
FQS62_RS04305	COG0285	dihydrofolate synthase activity
FQS62_RS04325	COG2833	Protein of unknown function (DUF455)
FQS62_RS04340	COG3291	Pkd domain containing protein
FQS62_RS04345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQS62_RS04350	COG0671	phosphoesterase, PA-phosphatase related
FQS62_RS04355	COG0438	transferase activity, transferring glycosyl groups
FQS62_RS04360	COG4771	TonB-dependent receptor
FQS62_RS04365	COG4206	TonB-dependent receptor
FQS62_RS04370	COG0248	Ppx GppA phosphatase
FQS62_RS04375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FQS62_RS04405	COG0473	3-isopropylmalate dehydrogenase activity
FQS62_RS04470	COG0544	peptidyl-prolyl cis-trans isomerase activity
FQS62_RS04475	COG0740	serine-type endopeptidase activity
FQS62_RS04480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FQS62_RS04520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FQS62_RS04525	COG1388	LysM domain
FQS62_RS04525	COG3942	CHAP domain
FQS62_RS04530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQS62_RS04540	COG0328	RNA-DNA hybrid ribonuclease activity
FQS62_RS04545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQS62_RS04550	COG0631	protein serine/threonine phosphatase activity
FQS62_RS04565	COG0859	PFAM glycosyl transferase family 9
FQS62_RS04575	COG1234	tRNA 3'-trailer cleavage
FQS62_RS04590	COG2076	Multidrug Resistance protein
FQS62_RS04620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FQS62_RS04630	COG0537	adenosine 5'-monophosphoramidase activity
FQS62_RS04650	COG0714	Associated with various cellular activities
FQS62_RS04665	COG1399	metal-binding, possibly nucleic acid-binding protein
FQS62_RS04670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FQS62_RS04675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQS62_RS04685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FQS62_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS04700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FQS62_RS04705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQS62_RS04710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FQS62_RS04720	COG0470	DNA polymerase III
FQS62_RS04795	COG0582	viral genome integration into host DNA
FQS62_RS04805	COG3209	COG3209 Rhs family protein
FQS62_RS04965	COG4774	siderophore transport
FQS62_RS04975	COG2223	nitrite transmembrane transporter activity
FQS62_RS04990	COG2226	methyltransferase
FQS62_RS05000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQS62_RS05005	COG0697	spore germination
FQS62_RS05010	COG0583	DNA-binding transcription factor activity
FQS62_RS05015	COG0477	Major facilitator Superfamily
FQS62_RS05050	COG0583	DNA-binding transcription factor activity
FQS62_RS05060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FQS62_RS05075	COG0667	Aldo Keto reductase
FQS62_RS05095	COG2818	Glycosylase
FQS62_RS05100	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FQS62_RS05105	COG1678	Uncharacterized ACR, COG1678
FQS62_RS05110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FQS62_RS05115	COG0540	Belongs to the ATCase OTCase family
FQS62_RS05135	COG2239	Acts as a magnesium transporter
FQS62_RS05140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQS62_RS05155	COG1660	Displays ATPase and GTPase activities
FQS62_RS05160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FQS62_RS05165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FQS62_RS05170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FQS62_RS05180	COG1137	ATPase activity
FQS62_RS05195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FQS62_RS05210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FQS62_RS05230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FQS62_RS05250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FQS62_RS05260	COG0628	permease
FQS62_RS05270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FQS62_RS05280	COG2261	transglycosylase associated protein
FQS62_RS05290	COG1555	photosystem II stabilization
FQS62_RS05310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FQS62_RS05315	COG1477	protein flavinylation
FQS62_RS05335	COG4771	TonB-dependent receptor
FQS62_RS05345	COG3128	pkhd-type hydroxylase
FQS62_RS05355	COG4774	siderophore transport
FQS62_RS05390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQS62_RS05395	COG0719	Fe-S assembly protein
FQS62_RS05400	COG0396	ATPase activity
FQS62_RS05405	COG0719	Fe-S assembly protein
FQS62_RS05410	COG1959	2 iron, 2 sulfur cluster binding
FQS62_RS05420	COG0693	protein deglycase activity
FQS62_RS05445	COG1764	response to oxidative stress
FQS62_RS05450	COG0384	phenazine biosynthesis protein PhzF
FQS62_RS05455	COG0384	phenazine biosynthesis protein PhzF
FQS62_RS05460	COG0527	aspartate kinase activity
FQS62_RS05470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FQS62_RS05490	COG0142	geranyltranstransferase activity
FQS62_RS05495	COG0366	Alpha amylase catalytic
FQS62_RS05505	COG1082	Xylose isomerase domain protein TIM barrel
FQS62_RS05515	COG2190	(PTS) system
FQS62_RS05515	COG2211	Major facilitator Superfamily
FQS62_RS05545	COG1131	(ABC) transporter
FQS62_RS05565	COG0629	single-stranded DNA binding
FQS62_RS05590	COG2010	Cytochrome c
FQS62_RS05600	COG0673	inositol 2-dehydrogenase activity
FQS62_RS05605	COG2211	Major facilitator Superfamily
FQS62_RS05615	COG1609	Transcriptional regulator
FQS62_RS05665	COG3655	Transcriptional regulator
FQS62_RS05670	COG1253	flavin adenine dinucleotide binding
FQS62_RS05680	COG1408	metallophosphoesterase
FQS62_RS05685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FQS62_RS05705	COG2259	Doxx family
FQS62_RS05735	COG0477	Major facilitator Superfamily
FQS62_RS05750	COG1802	Transcriptional regulator
FQS62_RS05785	COG3052	prosthetic group binding
FQS62_RS05800	COG0579	oxidoreductase
FQS62_RS05825	COG3104	oligopeptide transport
FQS62_RS05830	COG1297	OPT oligopeptide transporter protein
FQS62_RS05835	COG0823	Involved in the tonB-independent uptake of proteins
FQS62_RS05835	COG1506	peptidase
FQS62_RS05850	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FQS62_RS05855	COG2894	cell division
FQS62_RS05860	COG0850	regulation of cytokinetic process
FQS62_RS05870	COG4585	Histidine kinase
FQS62_RS05875	COG2197	response regulator
FQS62_RS05915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FQS62_RS05930	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FQS62_RS05940	COG1595	DNA-templated transcription, initiation
FQS62_RS05950	COG1946	Acyl-CoA thioesterase
FQS62_RS05970	COG0824	Thioesterase
FQS62_RS05975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQS62_RS05980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FQS62_RS05985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FQS62_RS05990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQS62_RS05995	COG0268	Binds directly to 16S ribosomal RNA
FQS62_RS06000	COG0728	peptidoglycan biosynthetic process
FQS62_RS06005	COG0196	riboflavin kinase activity
FQS62_RS06010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FQS62_RS06020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FQS62_RS06045	COG4206	TonB-dependent receptor
FQS62_RS06065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FQS62_RS06095	COG3209	COG3209 Rhs family protein
FQS62_RS06105	COG3209	COG3209 Rhs family protein
FQS62_RS06125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FQS62_RS06130	COG1845	cytochrome c oxidase, subunit III
FQS62_RS06135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FQS62_RS06150	COG0326	Molecular chaperone. Has ATPase activity
FQS62_RS06170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FQS62_RS06185	COG0228	four-way junction DNA binding
FQS62_RS06190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FQS62_RS06195	COG0336	Belongs to the RNA methyltransferase TrmD family
FQS62_RS06200	COG0335	large ribosomal subunit rRNA binding
FQS62_RS06220	COG0534	Mate efflux family protein
FQS62_RS06245	COG0753	catalase activity
FQS62_RS06455	COG5001	Diguanylate cyclase
FQS62_RS06455	COG3300	MHYT domain
FQS62_RS06615	COG1192	Involved in chromosome partitioning
FQS62_RS06680	COG0666	response to abiotic stimulus
FQS62_RS06690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FQS62_RS06740	COG0840	transmembrane signaling receptor activity
FQS62_RS06745	COG3134	Outer membrane lipoprotein
FQS62_RS06765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS06785	COG0024	Methionine aminopeptidase
FQS62_RS06810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FQS62_RS06835	COG1647	Serine aminopeptidase, S33
FQS62_RS06860	COG2814	Major facilitator Superfamily
FQS62_RS06865	COG3706	GGDEF domain
FQS62_RS06885	COG0588	phosphoglycerate mutase activity
FQS62_RS06890	COG3590	peptidase
FQS62_RS06900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FQS62_RS06910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FQS62_RS06915	COG0745	RESPONSE REGULATOR receiver
FQS62_RS06920	COG2205	protein histidine kinase activity
FQS62_RS06925	COG4452	Inner membrane protein CreD
FQS62_RS06940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQS62_RS06945	COG0735	belongs to the Fur family
FQS62_RS06985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FQS62_RS07025	COG5001	Diguanylate cyclase
FQS62_RS07025	COG5002	protein histidine kinase activity
FQS62_RS07035	COG1187	pseudouridine synthase activity
FQS62_RS07045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FQS62_RS07070	COG1132	(ABC) transporter
FQS62_RS07130	COG1695	Transcriptional regulator
FQS62_RS07150	COG1981	membrane
FQS62_RS07155	COG0825	malonyl-CoA metabolic process
FQS62_RS07180	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQS62_RS07190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQS62_RS07195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQS62_RS07200	COG0750	zinc metalloprotease
FQS62_RS07205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FQS62_RS07210	COG0575	Belongs to the CDS family
FQS62_RS07215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQS62_RS07220	COG0233	cytoplasmic translational termination
FQS62_RS07225	COG0528	UMP kinase activity
FQS62_RS07235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FQS62_RS07240	COG0052	Belongs to the universal ribosomal protein uS2 family
FQS62_RS07260	COG3188	usher protein
FQS62_RS07280	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FQS62_RS07295	COG1393	Belongs to the ArsC family
FQS62_RS07300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQS62_RS07310	COG0367	asparagine synthase
FQS62_RS07345	COG1566	PFAM secretion protein HlyD family protein
FQS62_RS07350	COG2814	Major facilitator Superfamily
FQS62_RS07365	COG0583	DNA-binding transcription factor activity
FQS62_RS07385	COG0557	exoribonuclease II activity
FQS62_RS07395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FQS62_RS07405	COG0577	efflux transmembrane transporter activity
FQS62_RS07405	COG1136	(ABC) transporter
FQS62_RS07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS07430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQS62_RS07435	COG2259	Doxx family
FQS62_RS07445	COG3220	belongs to the UPF0276 family
FQS62_RS07455	COG0704	Plays a role in the regulation of phosphate uptake
FQS62_RS07465	COG0581	inorganic phosphate transmembrane transporter activity
FQS62_RS07470	COG0573	inorganic phosphate transmembrane transporter activity
FQS62_RS07475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FQS62_RS07480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FQS62_RS07490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FQS62_RS07500	COG1024	Enoyl-CoA hydratase
FQS62_RS07530	COG0116	Belongs to the methyltransferase superfamily
FQS62_RS07530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FQS62_RS07550	COG2733	membrane
FQS62_RS07560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FQS62_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
FQS62_RS07575	COG0477	Major facilitator Superfamily
FQS62_RS07580	COG2703	oxygen carrier activity
FQS62_RS07605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQS62_RS07615	COG0174	glutamine synthetase
FQS62_RS07625	COG2072	flavoprotein involved in K transport
FQS62_RS07630	COG3842	ATPase activity
FQS62_RS07635	COG1176	ABC-type spermidine putrescine transport system, permease component I
FQS62_RS07640	COG1177	transmembrane transport
FQS62_RS07645	COG1012	belongs to the aldehyde dehydrogenase family
FQS62_RS07660	COG4535	Mg2 and Co2 transporter CorC
FQS62_RS07680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FQS62_RS07685	COG1702	phosphate starvation-inducible protein PhoH
FQS62_RS07690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS07695	COG1131	(ABC) transporter
FQS62_RS07700	COG0842	Transport permease protein
FQS62_RS07705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FQS62_RS07720	COG0741	lytic transglycosylase activity
FQS62_RS07725	COG0723	plastoquinol--plastocyanin reductase activity
FQS62_RS07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FQS62_RS07735	COG2857	Cytochrome c1
FQS62_RS07740	COG0625	glutathione transferase activity
FQS62_RS07745	COG2969	positive regulation of protein catabolic process
FQS62_RS07780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQS62_RS07790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FQS62_RS07805	COG1611	Belongs to the LOG family
FQS62_RS07850	COG0556	nucleotide-excision repair
FQS62_RS07890	COG3713	MltA-interacting MipA family protein
FQS62_RS07910	COG0811	peptide transport
FQS62_RS07930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FQS62_RS07935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQS62_RS07945	COG0322	excinuclease ABC activity
FQS62_RS07985	COG0577	efflux transmembrane transporter activity
FQS62_RS07985	COG1136	(ABC) transporter
FQS62_RS08030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQS62_RS08055	COG0583	DNA-binding transcription factor activity
FQS62_RS08075	COG1917	Cupin 2, conserved barrel domain protein
FQS62_RS08075	COG4977	sequence-specific DNA binding
FQS62_RS08080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FQS62_RS08100	COG0348	domain, Protein
FQS62_RS08115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FQS62_RS08130	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FQS62_RS08135	COG0069	glutamate synthase activity
FQS62_RS08160	COG1054	Belongs to the UPF0176 family
FQS62_RS08165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQS62_RS08180	COG1253	flavin adenine dinucleotide binding
FQS62_RS08200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FQS62_RS08215	COG0504	CTP synthase activity
FQS62_RS08235	COG0148	phosphopyruvate hydratase activity
FQS62_RS08240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FQS62_RS08245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FQS62_RS08250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FQS62_RS08260	COG2840	Smr protein MutS2
FQS62_RS08265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FQS62_RS08270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQS62_RS08290	COG1534	Rna-binding protein
FQS62_RS08295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FQS62_RS08300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQS62_RS08310	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FQS62_RS08315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FQS62_RS08320	COG1923	regulation of RNA biosynthetic process
FQS62_RS08325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FQS62_RS08330	COG1546	Belongs to the CinA family
FQS62_RS08335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FQS62_RS08340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FQS62_RS08345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FQS62_RS08350	COG2137	regulation of response to DNA damage stimulus
FQS62_RS08355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FQS62_RS08360	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FQS62_RS08385	COG4773	Receptor
FQS62_RS08400	COG1940	carbohydrate kinase activity
FQS62_RS08440	COG3540	Alkaline phosphatase
FQS62_RS08455	COG3258	Cytochrome c
FQS62_RS08470	COG2223	nitrite transmembrane transporter activity
FQS62_RS08485	COG1741	Belongs to the pirin family
FQS62_RS08490	COG0583	DNA-binding transcription factor activity
FQS62_RS08505	COG0352	thiamine-phosphate diphosphorylase activity
FQS62_RS08505	COG0351	phosphomethylpyrimidine kinase
FQS62_RS08520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FQS62_RS08525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FQS62_RS08535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQS62_RS08545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FQS62_RS08550	COG0477	Major facilitator Superfamily
FQS62_RS08560	COG0617	tRNA 3'-terminal CCA addition
FQS62_RS08570	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FQS62_RS08575	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FQS62_RS08585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FQS62_RS08590	COG0166	Belongs to the GPI family
FQS62_RS08605	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FQS62_RS08615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FQS62_RS08620	COG0671	phosphoesterase, PA-phosphatase related
FQS62_RS08630	COG0800	Aldolase
FQS62_RS08635	COG0129	dihydroxy-acid dehydratase activity
FQS62_RS08645	COG0837	glucose binding
FQS62_RS08670	COG2009	succinate dehydrogenase
FQS62_RS08675	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FQS62_RS08680	COG1053	succinate dehydrogenase
FQS62_RS08700	COG4591	ABC-type transport system involved in lipoprotein release permease component
FQS62_RS08715	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FQS62_RS08725	COG0552	protein localization to endoplasmic reticulum
FQS62_RS08740	COG0742	ribosomal rna small subunit methyltransferase
FQS62_RS08745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FQS62_RS08755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FQS62_RS08760	COG0405	Gamma-glutamyltransferase
FQS62_RS08765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQS62_RS08785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FQS62_RS08815	COG0415	Belongs to the DNA photolyase family
FQS62_RS08820	COG2885	chlorophyll binding
FQS62_RS08825	COG0583	DNA-binding transcription factor activity
FQS62_RS08890	COG1917	Cupin 2, conserved barrel domain protein
FQS62_RS08890	COG4977	sequence-specific DNA binding
FQS62_RS08980	COG0210	DNA helicase
FQS62_RS09035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FQS62_RS09050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQS62_RS09055	COG0735	belongs to the Fur family
FQS62_RS09065	COG0583	DNA-binding transcription factor activity
FQS62_RS09070	COG0497	DNA recombination
FQS62_RS09075	COG1420	regulation of RNA biosynthetic process
FQS62_RS09080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FQS62_RS09085	COG0443	Heat shock 70 kDa protein
FQS62_RS09095	COG2207	Transcriptional regulator
FQS62_RS09100	COG2223	nitrite transmembrane transporter activity
FQS62_RS09110	COG1605	Chorismate mutase
FQS62_RS09110	COG0287	Prephenate dehydrogenase
FQS62_RS09120	COG1132	(ABC) transporter
FQS62_RS09140	COG5001	Diguanylate cyclase
FQS62_RS09150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQS62_RS09155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FQS62_RS09160	COG0343	queuine tRNA-ribosyltransferase activity
FQS62_RS09165	COG1862	Preprotein translocase
FQS62_RS09175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQS62_RS09180	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FQS62_RS09195	COG4681	YaeQ
FQS62_RS09200	COG0564	pseudouridine synthase activity
FQS62_RS09215	COG0625	glutathione transferase activity
FQS62_RS09220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FQS62_RS09225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FQS62_RS09230	COG0513	Belongs to the DEAD box helicase family
FQS62_RS09240	COG0583	DNA-binding transcription factor activity
FQS62_RS09245	COG0488	(ABC) transporter
FQS62_RS09290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQS62_RS09295	COG2957	Belongs to the agmatine deiminase family
FQS62_RS09305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FQS62_RS09310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FQS62_RS09320	COG0776	regulation of translation
FQS62_RS09330	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FQS62_RS09335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FQS62_RS09345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FQS62_RS09350	COG0183	Belongs to the thiolase family
FQS62_RS09355	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQS62_RS09355	COG1024	Enoyl-CoA hydratase
FQS62_RS09365	COG0105	UTP biosynthetic process
FQS62_RS09370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FQS62_RS09390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQS62_RS09395	COG1160	GTP binding
FQS62_RS09405	COG0583	DNA-binding transcription factor activity
FQS62_RS09410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FQS62_RS09415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQS62_RS09415	COG0475	glutathione-regulated potassium exporter activity
FQS62_RS09435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQS62_RS09435	COG0519	Catalyzes the synthesis of GMP from XMP
FQS62_RS09475	COG0583	DNA-binding transcription factor activity
FQS62_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS09530	COG0640	Transcriptional regulator
FQS62_RS09575	COG4206	TonB-dependent receptor
FQS62_RS09580	COG0431	NADPH-dependent FMN reductase
FQS62_RS09590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQS62_RS09595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQS62_RS09600	COG1473	amidohydrolase
FQS62_RS09615	COG1126	abc transporter atp-binding protein
FQS62_RS09620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQS62_RS09640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FQS62_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS09660	COG1309	transcriptional regulator
FQS62_RS09675	COG0697	spore germination
FQS62_RS09680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FQS62_RS09685	COG0167	dihydroorotate dehydrogenase activity
FQS62_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
FQS62_RS09710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FQS62_RS09730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FQS62_RS09735	COG0438	transferase activity, transferring glycosyl groups
FQS62_RS09750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FQS62_RS09760	COG0489	protein tyrosine kinase activity
FQS62_RS09760	COG3206	protein involved in exopolysaccharide biosynthesis
FQS62_RS09765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQS62_RS09835	COG0745	RESPONSE REGULATOR receiver
FQS62_RS09840	COG0784	Response regulator, receiver
FQS62_RS09840	COG4191	Histidine kinase
FQS62_RS09850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FQS62_RS09860	COG2205	protein histidine kinase activity
FQS62_RS09910	COG0527	aspartate kinase activity
FQS62_RS09910	COG0460	homoserine dehydrogenase
FQS62_RS09915	COG0083	homoserine kinase activity
FQS62_RS09925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQS62_RS09930	COG0124	histidyl-tRNA synthetase
FQS62_RS09945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FQS62_RS09950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FQS62_RS09955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQS62_RS09960	COG0131	Imidazoleglycerol-phosphate dehydratase
FQS62_RS09960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FQS62_RS09965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FQS62_RS09970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FQS62_RS09975	COG0107	imidazoleglycerol-phosphate synthase activity
FQS62_RS09980	COG0140	phosphoribosyl-ATP diphosphatase activity
FQS62_RS09980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FQS62_RS10000	COG1446	asparaginase
FQS62_RS10005	COG3142	Participates in the control of copper homeostasis
FQS62_RS10020	COG0789	Transcriptional regulator
FQS62_RS10035	COG3537	Alpha-1,2-mannosidase
FQS62_RS10040	COG1609	Transcriptional regulator
FQS62_RS10050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQS62_RS10065	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FQS62_RS10070	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FQS62_RS10075	COG0235	Class ii aldolase
FQS62_RS10090	COG0531	amino acid
FQS62_RS10095	COG0531	amino acid
FQS62_RS10105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQS62_RS10110	COG0277	FAD linked oxidase domain protein
FQS62_RS10125	COG2205	protein histidine kinase activity
FQS62_RS10130	COG0745	RESPONSE REGULATOR receiver
FQS62_RS10140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS10155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FQS62_RS10200	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQS62_RS10215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FQS62_RS10220	COG0505	Belongs to the CarA family
FQS62_RS10225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FQS62_RS10230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FQS62_RS10250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FQS62_RS10255	COG4676	Protein conserved in bacteria
FQS62_RS10280	COG1012	belongs to the aldehyde dehydrogenase family
FQS62_RS10300	COG0784	Response regulator, receiver
FQS62_RS10300	COG2205	protein histidine kinase activity
FQS62_RS10300	COG2198	Histidine kinase
FQS62_RS10305	COG1024	Enoyl-CoA hydratase
FQS62_RS10310	COG0318	PFAM AMP-dependent synthetase and ligase
FQS62_RS10315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FQS62_RS10320	COG1012	belongs to the aldehyde dehydrogenase family
FQS62_RS10325	COG1309	transcriptional regulator
FQS62_RS10330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQS62_RS10365	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FQS62_RS10375	COG0840	transmembrane signaling receptor activity
FQS62_RS10380	COG0840	transmembrane signaling receptor activity
FQS62_RS10390	COG0835	chemotaxis
FQS62_RS10395	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FQS62_RS10400	COG0840	transmembrane signaling receptor activity
FQS62_RS10410	COG0745	RESPONSE REGULATOR receiver
FQS62_RS10420	COG0835	chemotaxis
FQS62_RS10435	COG1360	Flagellar Motor Protein
FQS62_RS10440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FQS62_RS10445	COG0784	Response regulator, receiver
FQS62_RS10445	COG2198	Histidine kinase
FQS62_RS10445	COG0643	Histidine kinase
FQS62_RS10450	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FQS62_RS10475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FQS62_RS10480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FQS62_RS10500	COG1987	bacterial-type flagellum assembly
FQS62_RS10510	COG3190	flagellar
FQS62_RS10560	COG1677	Flagellar hook-basal body complex protein FliE
FQS62_RS10585	COG2197	response regulator
FQS62_RS10605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FQS62_RS10645	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FQS62_RS10655	COG4787	bacterial-type flagellum-dependent cell motility
FQS62_RS10670	COG1558	bacterial-type flagellum-dependent cell motility
FQS62_RS10675	COG1815	bacterial-type flagellum-dependent cell motility
FQS62_RS10680	COG0784	Response regulator, receiver
FQS62_RS10680	COG0835	chemotaxis
FQS62_RS10700	COG5002	protein histidine kinase activity
FQS62_RS10740	COG2915	High frequency lysogenization protein hflD homolog
FQS62_RS10745	COG0482	sulfurtransferase activity
FQS62_RS10760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FQS62_RS10770	COG0542	response to heat
FQS62_RS10800	COG0492	ferredoxin-NADP+ reductase activity
FQS62_RS10805	COG1674	ftsk spoiiie
FQS62_RS10820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FQS62_RS10835	COG2819	hydrolase of the alpha beta superfamily
FQS62_RS10845	COG4558	Periplasmic binding protein
FQS62_RS10850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQS62_RS10855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FQS62_RS10870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FQS62_RS10885	COG0784	Response regulator, receiver
FQS62_RS10885	COG2198	Histidine kinase
FQS62_RS10885	COG2205	protein histidine kinase activity
FQS62_RS10890	COG2197	response regulator
FQS62_RS10930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FQS62_RS10940	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FQS62_RS10955	COG1595	DNA-templated transcription, initiation
FQS62_RS10975	COG0784	Response regulator, receiver
FQS62_RS10980	COG4251	negative regulation of phosphorylation
FQS62_RS10995	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FQS62_RS11005	COG0454	-acetyltransferase
FQS62_RS11005	COG0456	acetyltransferase
FQS62_RS11010	COG2205	protein histidine kinase activity
FQS62_RS11165	COG1294	oxidase, subunit
FQS62_RS11170	COG1271	oxidase subunit
FQS62_RS11175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FQS62_RS11180	COG0243	molybdopterin cofactor binding
FQS62_RS11185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQS62_RS11190	COG0315	cyclic pyranopterin monophosphate synthase activity
FQS62_RS11190	COG0521	Mo-molybdopterin cofactor biosynthetic process
FQS62_RS11195	COG0303	'Molybdopterin
FQS62_RS11205	COG0314	molybdopterin synthase activity
FQS62_RS11210	COG0746	molybdenum cofactor guanylyltransferase activity
FQS62_RS11220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FQS62_RS11225	COG4149	molybdate abc transporter
FQS62_RS11230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FQS62_RS11235	COG2204	response regulator
FQS62_RS11240	COG4191	Histidine kinase
FQS62_RS11245	COG3781	membrane
FQS62_RS11250	COG0556	nucleotide-excision repair
FQS62_RS11270	COG1252	NADH dehydrogenase
FQS62_RS11305	COG1252	NADH dehydrogenase
FQS62_RS11310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FQS62_RS11395	COG0789	Transcriptional regulator
FQS62_RS11400	COG2608	mercury ion transmembrane transporter activity
FQS62_RS11405	COG2608	mercury ion transmembrane transporter activity
FQS62_RS11415	COG0789	Transcriptional regulator
FQS62_RS11435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FQS62_RS11440	COG4644	lycopene metabolic process
FQS62_RS11475	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FQS62_RS11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS11505	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS11520	COG0010	Belongs to the arginase family
FQS62_RS11580	COG2132	Multicopper oxidase
FQS62_RS11605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FQS62_RS11660	COG4644	lycopene metabolic process
FQS62_RS11700	COG1902	pentaerythritol trinitrate reductase activity
FQS62_RS11715	COG1309	transcriptional regulator
FQS62_RS11845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FQS62_RS11850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FQS62_RS11855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FQS62_RS11860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FQS62_RS11865	COG2080	2 iron, 2 sulfur cluster binding
FQS62_RS11875	COG1764	response to oxidative stress
FQS62_RS11885	COG0583	DNA-binding transcription factor activity
FQS62_RS11905	COG1595	DNA-templated transcription, initiation
FQS62_RS11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQS62_RS11920	COG1309	transcriptional regulator
FQS62_RS11950	COG3685	Protein conserved in bacteria
FQS62_RS11995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FQS62_RS12015	COG1063	alcohol dehydrogenase
FQS62_RS12050	COG1609	Transcriptional regulator
FQS62_RS12055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQS62_RS12055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FQS62_RS12060	COG1105	Belongs to the carbohydrate kinase PfkB family
FQS62_RS12065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FQS62_RS12065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FQS62_RS12075	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FQS62_RS12090	COG4771	TonB-dependent receptor
FQS62_RS12095	COG0738	Major facilitator superfamily
FQS62_RS12100	COG1609	Transcriptional regulator
FQS62_RS12120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQS62_RS12135	COG2828	Protein conserved in bacteria
FQS62_RS12140	COG0583	DNA-binding transcription factor activity
FQS62_RS12175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FQS62_RS12180	COG0583	DNA-binding transcription factor activity
FQS62_RS12240	COG0318	PFAM AMP-dependent synthetase and ligase
FQS62_RS12250	COG2186	Transcriptional regulator
FQS62_RS12270	COG2271	Major facilitator Superfamily
FQS62_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS12285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQS62_RS12310	COG1404	Belongs to the peptidase S8 family
FQS62_RS12325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQS62_RS12345	COG0583	DNA-binding transcription factor activity
FQS62_RS12370	COG2204	response regulator
FQS62_RS12455	COG2199	diguanylate cyclase activity
FQS62_RS12465	COG0577	efflux transmembrane transporter activity
FQS62_RS12465	COG1136	(ABC) transporter
FQS62_RS12470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS12480	COG0745	RESPONSE REGULATOR receiver
FQS62_RS12485	COG2205	protein histidine kinase activity
FQS62_RS12505	COG4774	siderophore transport
FQS62_RS12535	COG4774	siderophore transport
FQS62_RS12545	COG0596	Alpha beta hydrolase
FQS62_RS12560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FQS62_RS12565	COG1285	pathogenesis
FQS62_RS12570	COG4191	Histidine kinase
FQS62_RS12575	COG4566	intracellular signal transduction
FQS62_RS12655	COG0477	Major facilitator Superfamily
FQS62_RS12695	COG0583	DNA-binding transcription factor activity
FQS62_RS12700	COG0656	L-ascorbic acid biosynthetic process
FQS62_RS12735	COG5002	protein histidine kinase activity
FQS62_RS12740	COG0583	DNA-binding transcription factor activity
FQS62_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS12775	COG3537	Alpha-1,2-mannosidase
FQS62_RS12800	COG0477	Major facilitator Superfamily
FQS62_RS12815	COG3920	Histidine kinase
FQS62_RS12815	COG2202	Pas domain
FQS62_RS12860	COG1335	isochorismatase
FQS62_RS12865	COG1335	isochorismatase
FQS62_RS12895	COG0811	peptide transport
FQS62_RS13040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FQS62_RS13055	COG0840	transmembrane signaling receptor activity
FQS62_RS13060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FQS62_RS13065	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FQS62_RS13070	COG4149	molybdate abc transporter
FQS62_RS13075	COG0725	ABC transporter, periplasmic molybdate-binding protein
FQS62_RS13080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQS62_RS13090	COG0746	molybdenum cofactor guanylyltransferase activity
FQS62_RS13095	COG0314	molybdopterin synthase activity
FQS62_RS13105	COG0303	'Molybdopterin
FQS62_RS13110	COG0315	cyclic pyranopterin monophosphate synthase activity
FQS62_RS13110	COG0521	Mo-molybdopterin cofactor biosynthetic process
FQS62_RS13115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQS62_RS13145	COG2207	Transcriptional regulator
FQS62_RS13185	COG2205	protein histidine kinase activity
FQS62_RS13195	COG2194	sulfuric ester hydrolase activity
FQS62_RS13215	COG2885	chlorophyll binding
FQS62_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQS62_RS13240	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FQS62_RS13245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQS62_RS13250	COG1535	isochorismatase
FQS62_RS13250	COG3433	isochorismatase activity
FQS62_RS13255	COG1535	isochorismatase
FQS62_RS13255	COG3433	isochorismatase activity
FQS62_RS13260	COG1021	2,3-dihydroxybenzoate-AMP ligase
FQS62_RS13265	COG1169	isochorismate synthase
FQS62_RS13275	COG2409	Drug exporters of the RND superfamily
FQS62_RS13280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQS62_RS13340	COG1914	H( )-stimulated, divalent metal cation uptake system
FQS62_RS13355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQS62_RS13360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQS62_RS13370	COG4206	TonB-dependent receptor
FQS62_RS13375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQS62_RS13420	COG4772	TonB-dependent receptor
FQS62_RS13540	COG2814	Major facilitator Superfamily
FQS62_RS13550	COG1228	amidohydrolase
FQS62_RS13560	COG1335	isochorismatase
FQS62_RS13580	COG2197	response regulator
FQS62_RS13585	COG2814	Major facilitator Superfamily
FQS62_RS13595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FQS62_RS13605	COG0583	DNA-binding transcription factor activity
FQS62_RS13620	COG3161	chorismate lyase activity
FQS62_RS13660	COG0277	FAD linked oxidase domain protein
FQS62_RS13665	COG1304	FMN binding
FQS62_RS13670	COG2186	Transcriptional regulator
FQS62_RS13680	COG1285	pathogenesis
FQS62_RS13760	COG0587	DNA-directed DNA polymerase activity
FQS62_RS13775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FQS62_RS13780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQS62_RS13780	COG0519	Catalyzes the synthesis of GMP from XMP
FQS62_RS13795	COG1595	DNA-templated transcription, initiation
FQS62_RS13805	COG4206	TonB-dependent receptor
FQS62_RS13805	COG1629	transport
FQS62_RS13835	COG0531	amino acid
FQS62_RS13850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FQS62_RS13860	COG0789	Transcriptional regulator
FQS62_RS13945	COG5002	protein histidine kinase activity
FQS62_RS13945	COG5001	Diguanylate cyclase
FQS62_RS13945	COG3447	MASE1 domain protein
FQS62_RS13950	COG2183	response to ionizing radiation
FQS62_RS13975	COG3243	poly(R)-hydroxyalkanoic acid synthase
FQS62_RS13990	COG1073	alpha beta
FQS62_RS13990	COG2226	methyltransferase
FQS62_RS13995	COG0534	Mate efflux family protein
FQS62_RS14015	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FQS62_RS14025	COG0668	transmembrane transport
FQS62_RS14030	COG1902	pentaerythritol trinitrate reductase activity
FQS62_RS14040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FQS62_RS14045	COG0590	tRNA wobble adenosine to inosine editing
FQS62_RS14050	COG1733	regulation of RNA biosynthetic process
FQS62_RS14055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQS62_RS14060	COG0456	acetyltransferase
FQS62_RS14120	COG3702	type iv secretory pathway
FQS62_RS14140	COG2948	multi-organism process
FQS62_RS14150	COG3736	Type IV secretory pathway, component VirB8
FQS62_RS14175	COG2814	Major facilitator Superfamily
FQS62_RS14180	COG0789	Transcriptional regulator
FQS62_RS14210	COG0784	Response regulator, receiver
FQS62_RS14210	COG4191	Histidine kinase
FQS62_RS14225	COG4774	siderophore transport
FQS62_RS14235	COG3133	Outer membrane lipoprotein
FQS62_RS14255	COG1733	regulation of RNA biosynthetic process
FQS62_RS14260	COG0604	alcohol dehydrogenase
FQS62_RS14275	COG0210	DNA helicase
FQS62_RS14295	COG0583	DNA-binding transcription factor activity
FQS62_RS14300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FQS62_RS14310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FQS62_RS14325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FQS62_RS14330	COG0077	Prephenate dehydratase
FQS62_RS14330	COG1605	Chorismate mutase
FQS62_RS14335	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FQS62_RS14370	COG1228	amidohydrolase
FQS62_RS14385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FQS62_RS14420	COG2957	Belongs to the agmatine deiminase family
FQS62_RS14425	COG0583	DNA-binding transcription factor activity
FQS62_RS14495	COG4993	Dehydrogenase
FQS62_RS14505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FQS62_RS14515	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FQS62_RS14525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQS62_RS14530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQS62_RS14545	COG0359	binds to the 23S rRNA
FQS62_RS14550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FQS62_RS14555	COG0360	Binds together with S18 to 16S ribosomal RNA
FQS62_RS14560	COG0316	Belongs to the HesB IscA family
FQS62_RS14565	COG0017	Asparaginyl-tRNA synthetase
FQS62_RS14585	COG0288	reversible hydration of carbon dioxide
FQS62_RS14595	COG3844	kynureninase activity
FQS62_RS14600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQS62_RS14605	COG2925	Exonuclease
FQS62_RS14630	COG2902	Dehydrogenase
FQS62_RS14640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS14645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS14655	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS14685	COG2900	Belongs to the SlyX family
FQS62_RS14700	COG0386	Belongs to the glutathione peroxidase family
FQS62_RS14710	COG1725	Transcriptional regulator
FQS62_RS14715	COG1131	(ABC) transporter
FQS62_RS14750	COG2850	peptidyl-arginine hydroxylation
FQS62_RS14760	COG0567	Dehydrogenase, E1 component
FQS62_RS14785	COG3540	Alkaline phosphatase
FQS62_RS14795	COG0305	Participates in initiation and elongation during chromosome replication
FQS62_RS14815	COG0625	glutathione transferase activity
FQS62_RS14840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FQS62_RS14875	COG0625	glutathione transferase activity
FQS62_RS14895	COG1595	DNA-templated transcription, initiation
FQS62_RS14900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQS62_RS14915	COG0386	Belongs to the glutathione peroxidase family
FQS62_RS14920	COG0339	signal peptide processing
FQS62_RS14925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FQS62_RS14945	COG0705	Rhomboid family
FQS62_RS14950	COG3104	oligopeptide transport
FQS62_RS14960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FQS62_RS14965	COG4290	ribonuclease
FQS62_RS14985	COG0316	Belongs to the HesB IscA family
FQS62_RS14985	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FQS62_RS14990	COG2154	pterin-4-alpha-carbinolamine dehydratase
FQS62_RS15000	COG0428	transporter
FQS62_RS15025	COG0395	ABC-type sugar transport system, permease component
FQS62_RS15055	COG0271	Belongs to the BolA IbaG family
FQS62_RS15060	COG2350	Protein conserved in bacteria
FQS62_RS15065	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FQS62_RS15070	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FQS62_RS15085	COG2814	Major facilitator Superfamily
FQS62_RS15105	COG0436	Aminotransferase
FQS62_RS15110	COG4133	protoheme IX ABC transporter activity
FQS62_RS15130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FQS62_RS15145	COG3088	subunit of a heme lyase
FQS62_RS15145	COG4235	cytochrome complex assembly
FQS62_RS15160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQS62_RS15170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FQS62_RS15175	COG4988	ABC transporter
FQS62_RS15185	COG1294	oxidase, subunit
FQS62_RS15215	COG0726	polysaccharide deacetylase
FQS62_RS15215	COG1649	PFAM Uncharacterised BCR, COG1649
FQS62_RS15220	COG1215	transferase activity, transferring glycosyl groups
FQS62_RS15230	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FQS62_RS15245	COG0165	Argininosuccinate lyase
FQS62_RS15250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FQS62_RS15260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FQS62_RS15265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQS62_RS15270	COG0137	argininosuccinate synthase activity
FQS62_RS15275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FQS62_RS15290	COG2166	iron-sulfur cluster assembly
FQS62_RS15310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQS62_RS15330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FQS62_RS15335	COG0402	S-adenosylhomocysteine deaminase activity
FQS62_RS15340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FQS62_RS15345	COG1509	lysine 2,3-aminomutase activity
FQS62_RS15350	COG3300	MHYT domain
FQS62_RS15350	COG5001	Diguanylate cyclase
FQS62_RS15370	COG0501	Belongs to the peptidase M48B family
FQS62_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS15400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FQS62_RS15405	COG0860	N-Acetylmuramoyl-L-alanine amidase
FQS62_RS15410	COG0802	atpase or kinase
FQS62_RS15415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FQS62_RS15415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FQS62_RS15420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FQS62_RS15425	COG1570	exodeoxyribonuclease VII activity
FQS62_RS15435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FQS62_RS15450	COG4771	TonB-dependent receptor
FQS62_RS15455	COG1309	transcriptional regulator
FQS62_RS15500	COG2130	NADP-dependent
FQS62_RS15540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FQS62_RS15575	COG2076	Multidrug Resistance protein
FQS62_RS15580	COG5487	UPF0391 membrane protein
FQS62_RS15585	COG1280	lysine exporter protein (LysE YggA)
FQS62_RS15590	COG1794	racemase activity, acting on amino acids and derivatives
FQS62_RS15630	COG0776	regulation of translation
FQS62_RS15635	COG0072	phenylalanine-tRNA ligase activity
FQS62_RS15635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQS62_RS15640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FQS62_RS15645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FQS62_RS15650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FQS62_RS15655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FQS62_RS15660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FQS62_RS15695	COG1185	polyribonucleotide nucleotidyltransferase activity
FQS62_RS15700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FQS62_RS15710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FQS62_RS15715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FQS62_RS15720	COG0195	Participates in both transcription termination and antitermination
FQS62_RS15725	COG0779	Required for maturation of 30S ribosomal subunits
FQS62_RS15740	COG1007	ATP synthesis coupled electron transport
FQS62_RS15755	COG0713	ATP synthesis coupled electron transport
FQS62_RS15765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQS62_RS15770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FQS62_RS15785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FQS62_RS15790	COG0649	NAD binding
FQS62_RS15795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQS62_RS15800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQS62_RS15805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQS62_RS15820	COG0149	triose-phosphate isomerase activity
FQS62_RS15830	COG3083	sulfuric ester hydrolase activity
FQS62_RS15835	COG0438	transferase activity, transferring glycosyl groups
FQS62_RS15840	COG0726	polysaccharide deacetylase
FQS62_RS15845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQS62_RS15850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FQS62_RS15855	COG0159	tryptophan synthase activity
FQS62_RS15865	COG0133	tryptophan synthase activity
FQS62_RS15905	COG0135	phosphoribosylanthranilate isomerase activity
FQS62_RS15910	COG0101	tRNA pseudouridine synthase activity
FQS62_RS15925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FQS62_RS15930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FQS62_RS15935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FQS62_RS15940	COG2890	protein-(glutamine-N5) methyltransferase activity
FQS62_RS15945	COG1999	signal sequence binding
FQS62_RS15950	COG0688	phosphatidylethanolamine metabolic process
FQS62_RS15965	COG0433	COG0433 Predicted ATPase
FQS62_RS15970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FQS62_RS15980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FQS62_RS15985	COG0412	Dienelactone hydrolase
FQS62_RS16000	COG0717	Belongs to the dCTP deaminase family
FQS62_RS16010	COG0489	protein tyrosine kinase activity
FQS62_RS16015	COG4771	TonB-dependent receptor
FQS62_RS16020	COG4771	TonB-dependent receptor
FQS62_RS16025	COG4771	TonB-dependent receptor
FQS62_RS16030	COG3590	peptidase
FQS62_RS16060	COG0697	spore germination
FQS62_RS16070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQS62_RS16075	COG2311	Membrane
FQS62_RS16080	COG1047	Peptidyl-prolyl cis-trans
FQS62_RS16085	COG0791	NLP P60 protein
FQS62_RS16090	COG0791	NLP P60 protein
FQS62_RS16095	COG1301	dicarboxylic acid transport
FQS62_RS16115	COG1722	exodeoxyribonuclease VII activity
FQS62_RS16120	COG0142	geranyltranstransferase activity
FQS62_RS16130	COG0312	modulator of DNA gyrase
FQS62_RS16135	COG3028	Belongs to the UPF0307 family
FQS62_RS16140	COG0312	modulator of DNA gyrase
FQS62_RS16160	COG2968	Membrane
FQS62_RS16170	COG4771	TonB-dependent receptor
FQS62_RS16180	COG2755	lipolytic protein G-D-S-L family
FQS62_RS16180	COG0657	acetylesterase activity
FQS62_RS16190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FQS62_RS16200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FQS62_RS16215	COG0495	leucyl-tRNA aminoacylation
FQS62_RS16225	COG3118	belongs to the thioredoxin family
FQS62_RS16235	COG2203	Gaf domain
FQS62_RS16235	COG3706	GGDEF domain
FQS62_RS16235	COG4251	negative regulation of phosphorylation
FQS62_RS16235	COG5001	Diguanylate cyclase
FQS62_RS16240	COG1943	Transposase
FQS62_RS16265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FQS62_RS16275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQS62_RS16280	COG0346	lactoylglutathione lyase activity
FQS62_RS16290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQS62_RS16290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQS62_RS16300	COG2878	Part of a membrane complex involved in electron transport
FQS62_RS16305	COG0251	oxidation-reduction process
FQS62_RS16310	COG0392	lysyltransferase activity
FQS62_RS16310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FQS62_RS16340	COG2824	Alkylphosphonate utilization operon protein PhnA
FQS62_RS16345	COG1077	Cell shape determining protein MreB Mrl
FQS62_RS16385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FQS62_RS16390	COG3122	Protein conserved in bacteria
FQS62_RS16395	COG1451	nucleotide metabolic process
FQS62_RS16405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FQS62_RS16425	COG0183	Belongs to the thiolase family
FQS62_RS16440	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS16450	COG1793	dna ligase
FQS62_RS16455	COG1201	RNA secondary structure unwinding
FQS62_RS16470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQS62_RS16475	COG1278	Cold shock
FQS62_RS16480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FQS62_RS16485	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FQS62_RS16490	COG1472	Belongs to the glycosyl hydrolase 3 family
FQS62_RS16495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FQS62_RS16500	COG2954	triphosphatase activity
FQS62_RS16505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FQS62_RS16510	COG0745	RESPONSE REGULATOR receiver
FQS62_RS16515	COG1381	Involved in DNA repair and RecF pathway recombination
FQS62_RS16520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FQS62_RS16535	COG0681	Belongs to the peptidase S26 family
FQS62_RS16540	COG0481	GTPase activity
FQS62_RS16545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQS62_RS16560	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQS62_RS16560	COG1024	Enoyl-CoA hydratase
FQS62_RS16565	COG1741	Belongs to the pirin family
FQS62_RS16570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FQS62_RS16580	COG1741	Belongs to the pirin family
FQS62_RS16585	COG1966	Carbon starvation protein
FQS62_RS16590	COG2879	small protein
FQS62_RS16600	COG2205	protein histidine kinase activity
FQS62_RS16605	COG0745	RESPONSE REGULATOR receiver
FQS62_RS16640	COG2814	Major facilitator Superfamily
FQS62_RS16645	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQS62_RS16645	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQS62_RS16655	COG1113	amino acid transport
FQS62_RS16660	COG1917	Cupin 2, conserved barrel domain protein
FQS62_RS16660	COG2207	Transcriptional regulator
FQS62_RS16665	COG0753	catalase activity
FQS62_RS16680	COG1376	ErfK ybiS ycfS ynhG family protein
FQS62_RS16685	COG0739	heme binding
FQS62_RS16695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FQS62_RS16705	COG0330	HflC and HflK could
FQS62_RS16710	COG0330	HflC and HflK could
FQS62_RS16715	COG0604	alcohol dehydrogenase
FQS62_RS16730	COG0678	peroxiredoxin activity
FQS62_RS16740	COG4953	penicillin-binding protein 1C
FQS62_RS16745	COG2373	Large extracellular alpha-helical protein
FQS62_RS16755	COG2079	MmgE PrpD family protein
FQS62_RS16760	COG2828	Protein conserved in bacteria
FQS62_RS16770	COG3609	addiction module antidote protein, CC2985 family
FQS62_RS16805	COG0259	pyridoxamine-phosphate oxidase activity
FQS62_RS16820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FQS62_RS16835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FQS62_RS16840	COG0477	Major facilitator Superfamily
FQS62_RS16860	COG3038	cytochrome b561
FQS62_RS16875	COG1760	l-serine dehydratase
FQS62_RS16880	COG2267	carboxylic ester hydrolase activity
FQS62_RS16885	COG0460	homoserine dehydrogenase
FQS62_RS16885	COG0527	aspartate kinase activity
FQS62_RS16890	COG0626	cystathionine gamma-synthase activity
FQS62_RS16895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQS62_RS16900	COG0739	heme binding
FQS62_RS16905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FQS62_RS16910	COG1272	protein, Hemolysin III
FQS62_RS16915	COG2982	Protein involved in outer membrane biogenesis
FQS62_RS16925	COG0463	Glycosyl transferase, family 2
FQS62_RS16930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQS62_RS16935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FQS62_RS16945	COG4206	TonB-dependent receptor
FQS62_RS16950	COG1309	transcriptional regulator
FQS62_RS16960	COG1960	acyl-CoA dehydrogenase activity
FQS62_RS16990	COG0583	DNA-binding transcription factor activity
FQS62_RS17005	COG0509	glycine decarboxylation via glycine cleavage system
FQS62_RS17010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FQS62_RS17020	COG0330	HflC and HflK could
FQS62_RS17030	COG1742	UPF0060 membrane protein
FQS62_RS17035	COG3956	TIGRFAM MazG family protein
FQS62_RS17045	COG0494	nUDIX hydrolase
FQS62_RS17055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FQS62_RS17070	COG2198	Histidine kinase
FQS62_RS17070	COG0784	Response regulator, receiver
FQS62_RS17070	COG0643	Histidine kinase
FQS62_RS17075	COG0840	transmembrane signaling receptor activity
FQS62_RS17080	COG0835	chemotaxis
FQS62_RS17110	COG1199	ATP-dependent helicase activity
FQS62_RS17120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQS62_RS17125	COG1215	transferase activity, transferring glycosyl groups
FQS62_RS17145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQS62_RS17155	COG1643	Atp-dependent helicase
FQS62_RS17160	COG0783	Belongs to the Dps family
FQS62_RS17165	COG0514	ATP-dependent DNA helicase (RecQ)
FQS62_RS17295	COG0789	Transcriptional regulator
FQS62_RS17315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FQS62_RS17320	COG0602	queuosine metabolic process
FQS62_RS17330	COG2885	chlorophyll binding
FQS62_RS17335	COG0823	Involved in the tonB-independent uptake of proteins
FQS62_RS17350	COG0811	peptide transport
FQS62_RS17355	COG0824	Thioesterase
FQS62_RS17360	COG2255	four-way junction helicase activity
FQS62_RS17370	COG0632	four-way junction helicase activity
FQS62_RS17375	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FQS62_RS17380	COG0217	transcriptional regulatory protein
FQS62_RS17400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FQS62_RS17430	COG0488	(ABC) transporter
FQS62_RS17450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQS62_RS17450	COG4651	solute:proton antiporter activity
FQS62_RS17460	COG0745	RESPONSE REGULATOR receiver
FQS62_RS17465	COG2205	protein histidine kinase activity
FQS62_RS17480	COG0542	response to heat
FQS62_RS17500	COG0028	Belongs to the TPP enzyme family
FQS62_RS17525	COG3387	PFAM Glycoside hydrolase 15-related
FQS62_RS17530	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FQS62_RS17550	COG0564	pseudouridine synthase activity
FQS62_RS17555	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQS62_RS17565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQS62_RS17565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQS62_RS17595	COG1132	(ABC) transporter
FQS62_RS17600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FQS62_RS17605	COG0045	succinate-CoA ligase (ADP-forming) activity
FQS62_RS17635	COG4969	Belongs to the N-Me-Phe pilin family
FQS62_RS17645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FQS62_RS17660	COG0745	RESPONSE REGULATOR receiver
FQS62_RS17675	COG0189	ligase activity
FQS62_RS17705	COG3240	lipase activity
FQS62_RS17705	COG4625	pathogenesis
FQS62_RS17715	COG2022	thiamine diphosphate biosynthetic process
FQS62_RS17720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FQS62_RS17725	COG0471	metal ion transport
FQS62_RS17725	COG3273	potassium ion transport
FQS62_RS17745	COG1970	mechanosensitive ion channel activity
FQS62_RS17760	COG1115	amino acid carrier protein
FQS62_RS17770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS17800	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FQS62_RS17810	COG3588	fructose-bisphosphate aldolase
FQS62_RS17815	COG0469	pyruvate kinase activity
FQS62_RS17825	COG0126	phosphoglycerate kinase activity
FQS62_RS17840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FQS62_RS17885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FQS62_RS17890	COG1301	dicarboxylic acid transport
FQS62_RS17900	COG2304	oxidoreductase activity
FQS62_RS17920	COG0714	Associated with various cellular activities
FQS62_RS17950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FQS62_RS18010	COG0254	rRNA binding
FQS62_RS18020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FQS62_RS18035	COG1758	RNA polymerase activity
FQS62_RS18050	COG0437	4 iron, 4 sulfur cluster binding
FQS62_RS18055	COG2864	formate dehydrogenase
FQS62_RS18065	COG1921	L-seryl-tRNASec selenium transferase activity
FQS62_RS18070	COG3276	selenocysteine insertion sequence binding
FQS62_RS18080	COG0709	Synthesizes selenophosphate from selenide and ATP
FQS62_RS18095	COG1561	YicC-like family, N-terminal region
FQS62_RS18100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FQS62_RS18105	COG0346	lactoylglutathione lyase activity
FQS62_RS18115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FQS62_RS18130	COG0006	proline dipeptidase activity
FQS62_RS18135	COG0006	proline dipeptidase activity
FQS62_RS18160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FQS62_RS18170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FQS62_RS18180	COG2912	Transglutaminase-like superfamily
FQS62_RS18185	COG1773	rubredoxin
FQS62_RS18195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQS62_RS18210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQS62_RS18215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQS62_RS18230	COG4221	oxidoreductase activity
FQS62_RS18255	COG0671	phosphoesterase, PA-phosphatase related
FQS62_RS18265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FQS62_RS18270	COG0563	adenylate kinase activity
FQS62_RS18290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FQS62_RS18300	COG0848	biopolymer transport protein
FQS62_RS18310	COG2832	Protein of unknown function (DUF454)
FQS62_RS18345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FQS62_RS18360	COG4771	TonB-dependent receptor
FQS62_RS18380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FQS62_RS18390	COG0405	Gamma-glutamyltransferase
FQS62_RS18400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FQS62_RS18420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FQS62_RS18425	COG2226	methyltransferase
FQS62_RS18440	COG0473	3-isopropylmalate dehydrogenase activity
FQS62_RS18475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQS62_RS18480	COG1538	Outer membrane efflux protein
FQS62_RS18490	COG1519	Transferase
FQS62_RS18495	COG1560	Kdo2-lipid A biosynthetic process
FQS62_RS18535	COG1301	dicarboxylic acid transport
FQS62_RS18545	COG4191	Histidine kinase
FQS62_RS18560	COG0642	Histidine kinase
FQS62_RS18575	COG2851	Citrate transporter
FQS62_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS18600	COG1162	GTPase activity
FQS62_RS18605	COG0436	Aminotransferase
FQS62_RS18640	COG1228	amidohydrolase
FQS62_RS18645	COG0804	urea catabolic process
FQS62_RS18655	COG1307	EDD domain protein, DegV family
FQS62_RS18695	COG5001	Diguanylate cyclase
FQS62_RS18695	COG4251	negative regulation of phosphorylation
FQS62_RS18695	COG3706	GGDEF domain
FQS62_RS18695	COG2203	Gaf domain
FQS62_RS18700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FQS62_RS18725	COG1902	pentaerythritol trinitrate reductase activity
FQS62_RS18755	COG0583	DNA-binding transcription factor activity
FQS62_RS18780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FQS62_RS18785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FQS62_RS18795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQS62_RS18815	COG1522	sequence-specific DNA binding
FQS62_RS18825	COG4773	Receptor
FQS62_RS18830	COG4206	TonB-dependent receptor
FQS62_RS18860	COG0617	tRNA 3'-terminal CCA addition
FQS62_RS18895	COG3468	outer membrane autotransporter barrel domain protein
FQS62_RS18905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FQS62_RS18915	COG1609	Transcriptional regulator
FQS62_RS18925	COG0837	glucose binding
FQS62_RS18935	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FQS62_RS18955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FQS62_RS18965	COG4191	Histidine kinase
FQS62_RS18970	COG0784	Response regulator, receiver
FQS62_RS18975	COG4251	negative regulation of phosphorylation
FQS62_RS18980	COG2823	Periplasmic or secreted lipoprotein
FQS62_RS18985	COG0673	inositol 2-dehydrogenase activity
FQS62_RS18995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FQS62_RS19015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FQS62_RS19020	COG0321	lipoyl(octanoyl) transferase activity
FQS62_RS19025	COG2921	Belongs to the UPF0250 family
FQS62_RS19055	COG2951	lytic endotransglycosylase activity
FQS62_RS19060	COG0772	Belongs to the SEDS family
FQS62_RS19065	COG0772	Belongs to the SEDS family
FQS62_RS19070	COG0768	penicillin binding
FQS62_RS19080	COG1792	Involved in formation and maintenance of cell shape
FQS62_RS19085	COG1077	Cell shape determining protein MreB Mrl
FQS62_RS19090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQS62_RS19105	COG0308	aminopeptidase N
FQS62_RS19110	COG2226	methyltransferase
FQS62_RS19140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS19155	COG0673	inositol 2-dehydrogenase activity
FQS62_RS19165	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FQS62_RS19190	COG2832	Protein of unknown function (DUF454)
FQS62_RS19205	COG1505	serine-type exopeptidase activity
FQS62_RS19230	COG0697	spore germination
FQS62_RS19235	COG1666	GTP binding
FQS62_RS19265	COG0339	signal peptide processing
FQS62_RS19275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FQS62_RS19290	COG4206	TonB-dependent receptor
FQS62_RS19315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQS62_RS19325	COG1136	(ABC) transporter
FQS62_RS19335	COG0577	efflux transmembrane transporter activity
FQS62_RS19335	COG1136	(ABC) transporter
FQS62_RS19345	COG2204	response regulator
FQS62_RS19350	COG4191	Histidine kinase
FQS62_RS19370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FQS62_RS19375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FQS62_RS19380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FQS62_RS19385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FQS62_RS19390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FQS62_RS19395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FQS62_RS19405	COG0356	it plays a direct role in the translocation of protons across the membrane
FQS62_RS19420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQS62_RS19425	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQS62_RS19445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FQS62_RS19450	COG1464	Belongs to the NlpA lipoprotein family
FQS62_RS19470	COG0181	hydroxymethylbilane synthase activity
FQS62_RS19480	COG0745	RESPONSE REGULATOR receiver
FQS62_RS19480	COG2972	Histidine kinase
FQS62_RS19495	COG4771	TonB-dependent receptor
FQS62_RS19510	COG0840	transmembrane signaling receptor activity
FQS62_RS19550	COG0477	Major facilitator Superfamily
FQS62_RS19585	COG0625	glutathione transferase activity
FQS62_RS19600	COG2259	Doxx family
FQS62_RS19630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FQS62_RS19635	COG1490	D-aminoacyl-tRNA deacylase activity
FQS62_RS19685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FQS62_RS19685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FQS62_RS19690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FQS62_RS19695	COG0242	peptide deformylase activity
FQS62_RS19710	COG2922	Belongs to the Smg family
FQS62_RS19720	COG1714	RDD family
FQS62_RS19725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FQS62_RS19725	COG1754	DNA topoisomerase type I activity
FQS62_RS19730	COG0009	L-threonylcarbamoyladenylate synthase
FQS62_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS19755	COG0616	signal peptide processing
FQS62_RS19760	COG0534	Mate efflux family protein
FQS62_RS19775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FQS62_RS19780	COG0625	glutathione transferase activity
FQS62_RS19790	COG1252	NADH dehydrogenase
FQS62_RS19805	COG2860	membrane
FQS62_RS19810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FQS62_RS19830	COG1846	Transcriptional regulator
FQS62_RS19865	COG0459	protein refolding
FQS62_RS19870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FQS62_RS19875	COG2356	endonuclease I
FQS62_RS19880	COG1324	tolerance protein
FQS62_RS19890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FQS62_RS19900	COG0840	transmembrane signaling receptor activity
FQS62_RS19920	COG4585	Histidine kinase
FQS62_RS19940	COG0583	DNA-binding transcription factor activity
FQS62_RS19950	COG1785	Belongs to the alkaline phosphatase family
FQS62_RS19955	COG1686	Belongs to the peptidase S11 family
FQS62_RS19965	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQS62_RS19975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FQS62_RS19985	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FQS62_RS19995	COG0511	ligase activity, forming carbon-carbon bonds
FQS62_RS20000	COG0439	Biotin carboxylase
FQS62_RS20015	COG2264	protein methyltransferase activity
FQS62_RS20025	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FQS62_RS20030	COG4589	Belongs to the CDS family
FQS62_RS20035	COG0204	Acyl-transferase
FQS62_RS20045	COG0671	phosphoesterase, PA-phosphatase related
FQS62_RS20045	COG2453	phosphatase
FQS62_RS20050	COG2267	carboxylic ester hydrolase activity
FQS62_RS20055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FQS62_RS20060	COG0138	bifunctional purine biosynthesis protein purh
FQS62_RS20070	COG0151	Belongs to the GarS family
FQS62_RS20085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FQS62_RS20090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FQS62_RS20095	COG2201	protein-glutamate methylesterase activity
FQS62_RS20105	COG2884	Cell division ATP-binding protein ftsE
FQS62_RS20115	COG3118	belongs to the thioredoxin family
FQS62_RS20125	COG3706	GGDEF domain
FQS62_RS20135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FQS62_RS20170	COG1652	LysM domain
FQS62_RS20175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FQS62_RS20175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FQS62_RS20180	COG1473	amidohydrolase
FQS62_RS20185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS20190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS20195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS20200	COG1289	transmembrane transporter activity
FQS62_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS20210	COG2814	Major facilitator Superfamily
FQS62_RS20240	COG0316	Belongs to the HesB IscA family
FQS62_RS20265	COG5002	protein histidine kinase activity
FQS62_RS20265	COG2205	protein histidine kinase activity
FQS62_RS20265	COG0784	Response regulator, receiver
FQS62_RS20280	COG1051	belongs to the nudix hydrolase family
FQS62_RS20295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FQS62_RS20300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FQS62_RS20305	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FQS62_RS20315	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FQS62_RS20320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQS62_RS20325	COG0730	response to heat
FQS62_RS20335	COG0134	indole-3-glycerol-phosphate synthase activity
FQS62_RS20340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQS62_RS20355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQS62_RS20360	COG1597	lipid kinase activity
FQS62_RS20375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FQS62_RS20380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FQS62_RS20390	COG2111	Na H antiporter
FQS62_RS20390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQS62_RS20395	COG1006	Multisubunit Na H antiporter MnhC subunit
FQS62_RS20400	COG0651	ATP synthesis coupled electron transport
FQS62_RS20405	COG1863	multisubunit Na H antiporter MnhE subunit
FQS62_RS20410	COG2212	antiporter activity
FQS62_RS20415	COG1320	monovalent cation:proton antiporter activity
FQS62_RS20420	COG0530	calcium, potassium:sodium antiporter activity
FQS62_RS20435	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FQS62_RS20460	COG3104	oligopeptide transport
FQS62_RS20465	COG3483	tryptophan 2,3-dioxygenase activity
FQS62_RS20495	COG2378	regulation of single-species biofilm formation
FQS62_RS20510	COG2354	Protein conserved in bacteria
FQS62_RS20520	COG1368	sulfuric ester hydrolase activity
FQS62_RS20525	COG3264	Mechanosensitive ion channel
FQS62_RS20525	COG1196	nuclear chromosome segregation
FQS62_RS20540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FQS62_RS20575	COG1166	arginine decarboxylase activity
FQS62_RS20580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FQS62_RS20600	COG2960	long-chain fatty acid transporting porin activity
FQS62_RS20710	COG0561	phosphatase activity
FQS62_RS20715	COG3932	Exopolysaccharide synthesis, ExoD
FQS62_RS20740	COG1999	signal sequence binding
FQS62_RS20745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FQS62_RS20750	COG1845	cytochrome c oxidase, subunit III
FQS62_RS20760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FQS62_RS20765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQS62_RS20780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQS62_RS20810	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FQS62_RS20835	COG2031	fatty acid transporter
FQS62_RS20865	COG0673	inositol 2-dehydrogenase activity
FQS62_RS20875	COG1501	Belongs to the glycosyl hydrolase 31 family
FQS62_RS20880	COG2222	sugar isomerase
FQS62_RS20885	COG1940	carbohydrate kinase activity
FQS62_RS20895	COG1349	DNA-binding transcription factor activity
FQS62_RS20900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FQS62_RS20905	COG2814	Major facilitator Superfamily
FQS62_RS20950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FQS62_RS20955	COG0156	8-amino-7-oxononanoate synthase activity
FQS62_RS20960	COG2267	carboxylic ester hydrolase activity
FQS62_RS20980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FQS62_RS21000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQS62_RS21005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQS62_RS21010	COG2205	protein histidine kinase activity
FQS62_RS21015	COG0745	RESPONSE REGULATOR receiver
FQS62_RS21020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FQS62_RS21045	COG0714	Associated with various cellular activities
FQS62_RS21060	COG0754	glutathionylspermidine amidase activity
FQS62_RS21075	COG1199	ATP-dependent helicase activity
FQS62_RS21085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FQS62_RS21105	COG3781	membrane
FQS62_RS21135	COG0625	glutathione transferase activity
FQS62_RS21155	COG2207	Transcriptional regulator
FQS62_RS21300	COG4771	TonB-dependent receptor
FQS62_RS21305	COG4221	oxidoreductase activity
FQS62_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS21315	COG0583	DNA-binding transcription factor activity
FQS62_RS21350	COG0543	2 iron, 2 sulfur cluster binding
FQS62_RS21350	COG0633	Ferredoxin
FQS62_RS21355	COG1131	(ABC) transporter
FQS62_RS21360	COG0842	Transport permease protein
FQS62_RS21370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FQS62_RS21380	COG0084	hydrolase, TatD family'
FQS62_RS21395	COG1187	pseudouridine synthase activity
FQS62_RS21405	COG0667	Aldo Keto reductase
FQS62_RS21420	COG1690	Belongs to the RtcB family
FQS62_RS21430	COG1959	2 iron, 2 sulfur cluster binding
FQS62_RS21440	COG0583	DNA-binding transcription factor activity
FQS62_RS21445	COG2814	Major facilitator Superfamily
FQS62_RS21450	COG0656	L-ascorbic acid biosynthetic process
FQS62_RS21455	COG2267	carboxylic ester hydrolase activity
FQS62_RS21465	COG0045	succinate-CoA ligase (ADP-forming) activity
FQS62_RS21465	COG1042	CoA-binding domain protein
FQS62_RS21465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FQS62_RS21470	COG2239	Acts as a magnesium transporter
FQS62_RS21480	COG0666	response to abiotic stimulus
FQS62_RS21480	COG3177	Filamentation induced by cAMP protein fic
FQS62_RS21485	COG3100	YcgL domain-containing protein
FQS62_RS21490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FQS62_RS21495	COG1028	Short-chain dehydrogenase reductase Sdr
FQS62_RS21530	COG2986	histidine ammonia-lyase
FQS62_RS21545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FQS62_RS21555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQS62_RS21560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQS62_RS21575	COG1294	oxidase, subunit
FQS62_RS21580	COG1271	oxidase subunit
FQS62_RS21615	COG1595	DNA-templated transcription, initiation
FQS62_RS21650	COG0408	coproporphyrinogen oxidase activity
FQS62_RS21660	COG2323	membrane
FQS62_RS21675	COG0589	response to stress
FQS62_RS21695	COG0210	DNA helicase
FQS62_RS21705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FQS62_RS21710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FQS62_RS21715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FQS62_RS21730	COG0251	oxidation-reduction process
FQS62_RS21770	COG0463	Glycosyl transferase, family 2
FQS62_RS21785	COG1475	DNA binding
FQS62_RS21790	COG1192	Involved in chromosome partitioning
FQS62_RS21795	COG0357	Ribosomal RNA small subunit methyltransferase G
FQS62_RS21800	COG2091	lysine biosynthetic process via aminoadipic acid
FQS62_RS21840	COG1971	Probably functions as a manganese efflux pump
FQS62_RS21845	COG0784	Response regulator, receiver
FQS62_RS21845	COG2205	protein histidine kinase activity
FQS62_RS21855	COG2911	Protein conserved in bacteria
FQS62_RS21860	COG0729	surface antigen
FQS62_RS21870	COG0752	glycyl-tRNA synthetase alpha subunit
FQS62_RS21875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FQS62_RS21880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQS62_RS21880	COG0519	Catalyzes the synthesis of GMP from XMP
FQS62_RS21890	COG0805	protein transport
FQS62_RS21900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FQS62_RS21910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FQS62_RS21920	COG0840	transmembrane signaling receptor activity
FQS62_RS21975	COG3135	benzoate transporter
FQS62_RS21990	COG2951	lytic endotransglycosylase activity
FQS62_RS21995	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FQS62_RS22000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FQS62_RS22005	COG3706	GGDEF domain
FQS62_RS22035	COG0302	gtp cyclohydrolase
FQS62_RS22060	COG1289	transmembrane transporter activity
FQS62_RS22075	COG1074	ATP-dependent DNA helicase activity
FQS62_RS22080	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FQS62_RS22085	COG1127	ABC transporter
FQS62_RS22090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FQS62_RS22095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FQS62_RS22110	COG2853	Lipoprotein
FQS62_RS22115	COG0386	Belongs to the glutathione peroxidase family
FQS62_RS22125	COG1322	Protein conserved in bacteria
FQS62_RS22135	COG0604	alcohol dehydrogenase
FQS62_RS22140	COG0583	DNA-binding transcription factor activity
FQS62_RS22160	COG0667	Aldo Keto reductase
FQS62_RS22165	COG0531	amino acid
FQS62_RS22185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FQS62_RS22190	COG0861	Integral membrane protein TerC family
FQS62_RS22200	COG0584	glycerophosphoryl diester phosphodiesterase
FQS62_RS22215	COG0706	membrane insertase activity
FQS62_RS22220	COG0594	ribonuclease P activity
FQS62_RS22225	COG0230	Belongs to the bacterial ribosomal protein bL34 family