locus-tag	class	description
GOC52_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GOC52_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GOC52_RS00020	COG0187	DNA topoisomerase II activity
GOC52_RS00030	COG0501	Belongs to the peptidase M48B family
GOC52_RS00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GOC52_RS00095	COG4772	TonB-dependent receptor
GOC52_RS00130	COG0800	Aldolase
GOC52_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOC52_RS00155	COG2272	Belongs to the type-B carboxylesterase lipase family
GOC52_RS00170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GOC52_RS00185	COG3507	Belongs to the glycosyl hydrolase 43 family
GOC52_RS00190	COG1609	Transcriptional regulator
GOC52_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS00205	COG2755	lipolytic protein G-D-S-L family
GOC52_RS00215	COG3186	Phenylalanine-4-hydroxylase
GOC52_RS00220	COG1522	sequence-specific DNA binding
GOC52_RS00230	COG1752	Esterase of the alpha-beta hydrolase superfamily
GOC52_RS00245	COG0671	phosphoesterase, PA-phosphatase related
GOC52_RS00260	COG1119	ATPase activity
GOC52_RS00275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GOC52_RS00280	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GOC52_RS00290	COG1435	thymidine kinase activity
GOC52_RS00295	COG0210	DNA helicase
GOC52_RS00305	COG3132	Protein of unknown function, DUF480
GOC52_RS00310	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GOC52_RS00315	COG0284	orotidine-5'-phosphate decarboxylase activity
GOC52_RS00325	COG2937	Belongs to the GPAT DAPAT family
GOC52_RS00335	COG0037	tRNA processing
GOC52_RS00340	COG2974	May be involved in recombination
GOC52_RS00350	COG1803	Methylglyoxal synthase
GOC52_RS00355	COG2205	protein histidine kinase activity
GOC52_RS00355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GOC52_RS00360	COG0493	'glutamate synthase
GOC52_RS00365	COG0070	glutamate synthase
GOC52_RS00365	COG0069	glutamate synthase activity
GOC52_RS00365	COG0067	glutamate synthase
GOC52_RS00385	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS00415	COG1205	dead DEAH box helicase
GOC52_RS00415	COG1111	helicase
GOC52_RS00455	COG0714	Associated with various cellular activities
GOC52_RS00475	COG0312	modulator of DNA gyrase
GOC52_RS00485	COG3550	peptidyl-serine autophosphorylation
GOC52_RS00505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOC52_RS00525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOC52_RS00560	COG1968	undecaprenyl-diphosphatase activity
GOC52_RS00565	COG0174	glutamine synthetase
GOC52_RS00570	COG0347	Belongs to the P(II) protein family
GOC52_RS00575	COG0004	ammonium transporteR
GOC52_RS00580	COG3023	N-Acetylmuramoyl-L-alanine amidase
GOC52_RS00585	COG3279	Response regulator of the LytR AlgR family
GOC52_RS00600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GOC52_RS00615	COG3852	Histidine kinase
GOC52_RS00620	COG2204	response regulator
GOC52_RS00625	COG2032	superoxide dismutase activity
GOC52_RS00630	COG2032	superoxide dismutase activity
GOC52_RS00640	COG0183	Belongs to the thiolase family
GOC52_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GOC52_RS00680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GOC52_RS00700	COG0798	PFAM Bile acid sodium symporter
GOC52_RS00715	COG0431	NADPH-dependent FMN reductase
GOC52_RS00750	COG2837	iron assimilation
GOC52_RS00790	COG2197	response regulator
GOC52_RS00795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GOC52_RS00795	COG2205	protein histidine kinase activity
GOC52_RS00800	COG3474	cytochrome
GOC52_RS00810	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS00815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GOC52_RS00825	COG0612	Peptidase, M16
GOC52_RS00835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOC52_RS00840	COG0596	Alpha beta hydrolase
GOC52_RS00850	COG0318	PFAM AMP-dependent synthetase and ligase
GOC52_RS00855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOC52_RS00865	COG1181	Belongs to the D-alanine--D-alanine ligase family
GOC52_RS00905	COG0339	signal peptide processing
GOC52_RS00920	COG0681	Belongs to the peptidase S26 family
GOC52_RS00925	COG2814	Major facilitator Superfamily
GOC52_RS00930	COG0583	DNA-binding transcription factor activity
GOC52_RS00935	COG0443	Heat shock 70 kDa protein
GOC52_RS00945	COG0583	DNA-binding transcription factor activity
GOC52_RS00950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GOC52_RS00955	COG2224	Isocitrate lyase
GOC52_RS00960	COG3706	GGDEF domain
GOC52_RS00985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GOC52_RS00990	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS01010	COG0697	spore germination
GOC52_RS01020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GOC52_RS01035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOC52_RS01040	COG1280	lysine exporter protein (LysE YggA)
GOC52_RS01045	COG1607	acyl-coa hydrolase
GOC52_RS01055	COG1902	pentaerythritol trinitrate reductase activity
GOC52_RS01070	COG1335	isochorismatase
GOC52_RS01075	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GOC52_RS01080	COG1752	Esterase of the alpha-beta hydrolase superfamily
GOC52_RS01085	COG1396	sequence-specific DNA binding
GOC52_RS01085	COG3800	Transcriptional regulator
GOC52_RS01095	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS01100	COG1024	Enoyl-CoA hydratase
GOC52_RS01105	COG1024	Enoyl-CoA hydratase
GOC52_RS01115	COG1764	response to oxidative stress
GOC52_RS01125	COG0659	secondary active sulfate transmembrane transporter activity
GOC52_RS01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOC52_RS01160	COG3228	Belongs to the MtfA family
GOC52_RS01170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GOC52_RS01170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GOC52_RS01175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GOC52_RS01225	COG3237	CsbD-like
GOC52_RS01235	COG0180	Tryptophanyl-tRNA synthetase
GOC52_RS01260	COG0477	Major facilitator Superfamily
GOC52_RS01265	COG0697	spore germination
GOC52_RS01280	COG1136	(ABC) transporter
GOC52_RS01280	COG0577	efflux transmembrane transporter activity
GOC52_RS01290	COG1136	(ABC) transporter
GOC52_RS01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS01300	COG1131	(ABC) transporter
GOC52_RS01310	COG4585	Histidine kinase
GOC52_RS01315	COG2197	response regulator
GOC52_RS01330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GOC52_RS01345	COG0628	permease
GOC52_RS01365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOC52_RS01380	COG5507	3-demethylubiquinone-9 3-methyltransferase
GOC52_RS01410	COG2814	Major facilitator Superfamily
GOC52_RS01415	COG0583	DNA-binding transcription factor activity
GOC52_RS01420	COG4807	Protein conserved in bacteria
GOC52_RS01430	COG4221	oxidoreductase activity
GOC52_RS01440	COG0018	arginyl-trna synthetase
GOC52_RS01445	COG2003	Belongs to the UPF0758 family
GOC52_RS01450	COG2197	response regulator
GOC52_RS01455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GOC52_RS01460	COG0756	dUTP diphosphatase activity
GOC52_RS01475	COG2205	protein histidine kinase activity
GOC52_RS01485	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GOC52_RS01490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GOC52_RS01505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GOC52_RS01510	COG0708	Exodeoxyribonuclease III
GOC52_RS01515	COG2223	nitrite transmembrane transporter activity
GOC52_RS01530	COG0739	heme binding
GOC52_RS01605	COG4942	peptidase
GOC52_RS01610	COG0793	Belongs to the peptidase S41A family
GOC52_RS01640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GOC52_RS01670	COG3346	SURF1 family
GOC52_RS01685	COG0109	protoheme IX farnesyltransferase activity
GOC52_RS01700	COG0358	DNA primase activity
GOC52_RS01705	COG1295	ribonuclease BN
GOC52_RS01720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GOC52_RS01730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GOC52_RS01735	COG0668	transmembrane transport
GOC52_RS01750	COG2133	pyrroloquinoline quinone binding
GOC52_RS01755	COG4682	membrane
GOC52_RS01765	COG0531	amino acid
GOC52_RS01775	COG1737	Transcriptional regulator
GOC52_RS01780	COG4948	Mandelate Racemase Muconate Lactonizing
GOC52_RS01830	COG5383	Protein conserved in bacteria
GOC52_RS01840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GOC52_RS01845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GOC52_RS01875	COG0778	Nitroreductase
GOC52_RS01880	COG2353	YceI-like domain
GOC52_RS01895	COG2375	cellular response to nickel ion
GOC52_RS01985	COG2267	carboxylic ester hydrolase activity
GOC52_RS02050	COG0488	(ABC) transporter
GOC52_RS02055	COG0583	DNA-binding transcription factor activity
GOC52_RS02065	COG2814	Major facilitator Superfamily
GOC52_RS02070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GOC52_RS02075	COG1113	amino acid transport
GOC52_RS02080	COG0741	lytic transglycosylase activity
GOC52_RS02110	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GOC52_RS02120	COG5507	3-demethylubiquinone-9 3-methyltransferase
GOC52_RS02125	COG4941	Belongs to the sigma-70 factor family
GOC52_RS02155	COG3275	phosphorelay sensor kinase activity
GOC52_RS02160	COG3279	Response regulator of the LytR AlgR family
GOC52_RS02180	COG3590	peptidase
GOC52_RS02185	COG5001	Diguanylate cyclase
GOC52_RS02190	COG0583	DNA-binding transcription factor activity
GOC52_RS02200	COG3384	dioxygenase
GOC52_RS02205	COG0025	NhaP-type Na H and K H
GOC52_RS02230	COG1360	Flagellar Motor Protein
GOC52_RS02260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GOC52_RS02275	COG5002	protein histidine kinase activity
GOC52_RS02290	COG2813	Specifically methylates the guanine in position
GOC52_RS02295	COG1187	pseudouridine synthase activity
GOC52_RS02300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOC52_RS02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GOC52_RS02315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GOC52_RS02330	COG0583	DNA-binding transcription factor activity
GOC52_RS02335	COG2226	methyltransferase
GOC52_RS02360	COG1956	GAF domain-containing protein
GOC52_RS02365	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GOC52_RS02370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOC52_RS02375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GOC52_RS02380	COG0785	Cytochrome C biogenesis protein
GOC52_RS02380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS02385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GOC52_RS02390	COG0745	RESPONSE REGULATOR receiver
GOC52_RS02395	COG5002	protein histidine kinase activity
GOC52_RS02400	COG2205	protein histidine kinase activity
GOC52_RS02405	COG0745	RESPONSE REGULATOR receiver
GOC52_RS02410	COG0367	asparagine synthase
GOC52_RS02420	COG0720	synthase
GOC52_RS02435	COG0513	Belongs to the DEAD box helicase family
GOC52_RS02445	COG0625	glutathione transferase activity
GOC52_RS02485	COG0626	cystathionine gamma-synthase activity
GOC52_RS02500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GOC52_RS02560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOC52_RS02585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOC52_RS02590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOC52_RS02620	COG1127	ABC transporter
GOC52_RS02625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GOC52_RS02640	COG0442	prolyl-tRNA aminoacylation
GOC52_RS02650	COG1183	phosphatidylcholine synthase activity
GOC52_RS02660	COG0456	acetyltransferase
GOC52_RS02670	COG0525	valine-tRNA ligase activity
GOC52_RS02680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GOC52_RS02690	COG0795	lipopolysaccharide-transporting ATPase activity
GOC52_RS02700	COG4974	Belongs to the 'phage' integrase family
GOC52_RS02705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GOC52_RS02715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GOC52_RS02715	COG0047	phosphoribosylformylglycinamidine synthase activity
GOC52_RS02720	COG5295	Hep Hag repeat protein
GOC52_RS02725	COG1404	Belongs to the peptidase S8 family
GOC52_RS02730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GOC52_RS02735	COG1459	type II secretion system
GOC52_RS02740	COG2165	general secretion pathway protein
GOC52_RS02745	COG4970	Tfp pilus assembly protein FimT
GOC52_RS02750	COG2165	general secretion pathway protein
GOC52_RS02755	COG4795	General secretion pathway protein
GOC52_RS02760	COG3156	type II secretion system protein K
GOC52_RS02765	COG3166	PFAM Fimbrial assembly family protein
GOC52_RS02780	COG1450	Type ii and iii secretion system protein
GOC52_RS02790	COG0463	Glycosyl transferase, family 2
GOC52_RS02805	COG3539	Fimbrial protein
GOC52_RS02825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GOC52_RS02835	COG1215	transferase activity, transferring glycosyl groups
GOC52_RS02850	COG2252	PERMEase
GOC52_RS02855	COG0488	(ABC) transporter
GOC52_RS02865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GOC52_RS02880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GOC52_RS02885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOC52_RS02885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOC52_RS02910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GOC52_RS02915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOC52_RS02950	COG2755	lipolytic protein G-D-S-L family
GOC52_RS02950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOC52_RS02955	COG0277	FAD linked oxidase domain protein
GOC52_RS02960	COG1988	membrane-bound metal-dependent
GOC52_RS02995	COG2001	Belongs to the MraZ family
GOC52_RS03000	COG0275	rRNA processing
GOC52_RS03005	COG3116	cell division
GOC52_RS03020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GOC52_RS03040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GOC52_RS03045	COG1181	Belongs to the D-alanine--D-alanine ligase family
GOC52_RS03050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GOC52_RS03060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GOC52_RS03065	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GOC52_RS03075	COG0739	heme binding
GOC52_RS03080	COG0653	protein targeting
GOC52_RS03085	COG0494	nUDIX hydrolase
GOC52_RS03095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GOC52_RS03105	COG3275	phosphorelay sensor kinase activity
GOC52_RS03115	COG0402	S-adenosylhomocysteine deaminase activity
GOC52_RS03135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GOC52_RS03140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GOC52_RS03150	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GOC52_RS03155	COG1607	acyl-coa hydrolase
GOC52_RS03165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GOC52_RS03185	COG4106	trans-aconitate 2-methyltransferase activity
GOC52_RS03190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOC52_RS03210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOC52_RS03215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GOC52_RS03220	COG0667	Aldo Keto reductase
GOC52_RS03230	COG4771	TonB-dependent receptor
GOC52_RS03245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GOC52_RS03250	COG4181	ATPase activity
GOC52_RS03265	COG0642	Histidine kinase
GOC52_RS03275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GOC52_RS03280	COG0861	Integral membrane protein TerC family
GOC52_RS03285	COG2814	Major facilitator Superfamily
GOC52_RS03290	COG1704	LemA family
GOC52_RS03305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GOC52_RS03310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GOC52_RS03325	COG3738	Protein conserved in bacteria
GOC52_RS03330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GOC52_RS03335	COG2967	ApaG domain
GOC52_RS03340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GOC52_RS03345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GOC52_RS03350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GOC52_RS03355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GOC52_RS03365	COG2096	Adenosyltransferase
GOC52_RS03375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GOC52_RS03380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GOC52_RS03385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GOC52_RS03390	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GOC52_RS03410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOC52_RS03420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GOC52_RS03430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GOC52_RS03435	COG0583	DNA-binding transcription factor activity
GOC52_RS03440	COG3634	alkyl hydroperoxide reductase activity
GOC52_RS03500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GOC52_RS03525	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GOC52_RS03540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GOC52_RS03560	COG1404	Belongs to the peptidase S8 family
GOC52_RS03580	COG1295	ribonuclease BN
GOC52_RS03585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS03600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GOC52_RS03605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GOC52_RS03620	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GOC52_RS03630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GOC52_RS03635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GOC52_RS03640	COG0193	aminoacyl-tRNA hydrolase activity
GOC52_RS03645	COG0012	GTP binding
GOC52_RS03650	COG4206	TonB-dependent receptor
GOC52_RS03655	COG4242	Belongs to the peptidase S51 family
GOC52_RS03680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOC52_RS03695	COG0250	Participates in transcription elongation, termination and antitermination
GOC52_RS03700	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GOC52_RS03705	COG0081	regulation of translation
GOC52_RS03710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GOC52_RS03715	COG0222	ribosome binding
GOC52_RS03720	COG0085	RNA polymerase activity
GOC52_RS03725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GOC52_RS03730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GOC52_RS03735	COG0049	tRNA binding
GOC52_RS03740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GOC52_RS03745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOC52_RS03750	COG0051	transcription antitermination factor activity, RNA binding
GOC52_RS03755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GOC52_RS03760	COG0088	Forms part of the polypeptide exit tunnel
GOC52_RS03765	COG0089	rRNA binding
GOC52_RS03770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GOC52_RS03775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GOC52_RS03780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GOC52_RS03785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GOC52_RS03790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GOC52_RS03795	COG0255	Belongs to the universal ribosomal protein uL29 family
GOC52_RS03800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GOC52_RS03805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GOC52_RS03810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GOC52_RS03815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GOC52_RS03820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GOC52_RS03825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GOC52_RS03830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GOC52_RS03835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GOC52_RS03840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GOC52_RS03845	COG1841	ribosomal large subunit assembly
GOC52_RS03850	COG0200	Binds to the 23S rRNA
GOC52_RS03855	COG0201	protein transport
GOC52_RS03860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GOC52_RS03865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GOC52_RS03870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GOC52_RS03875	COG0202	RNA polymerase activity
GOC52_RS03880	COG0203	ribosomal protein L17
GOC52_RS03895	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GOC52_RS03910	COG0154	amidase activity
GOC52_RS03925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GOC52_RS03930	COG0039	L-malate dehydrogenase activity
GOC52_RS03935	COG0564	pseudouridine synthase activity
GOC52_RS03940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GOC52_RS03955	COG0625	glutathione transferase activity
GOC52_RS03965	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOC52_RS03965	COG1902	pentaerythritol trinitrate reductase activity
GOC52_RS03970	COG2364	Membrane
GOC52_RS03975	COG0604	alcohol dehydrogenase
GOC52_RS03990	COG1187	pseudouridine synthase activity
GOC52_RS04010	COG1063	alcohol dehydrogenase
GOC52_RS04050	COG0406	alpha-ribazole phosphatase activity
GOC52_RS04055	COG0285	dihydrofolate synthase activity
GOC52_RS04075	COG2833	Protein of unknown function (DUF455)
GOC52_RS04085	COG3291	Pkd domain containing protein
GOC52_RS04090	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOC52_RS04100	COG0438	transferase activity, transferring glycosyl groups
GOC52_RS04110	COG4206	TonB-dependent receptor
GOC52_RS04115	COG0248	Ppx GppA phosphatase
GOC52_RS04120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GOC52_RS04135	COG4783	chaperone-mediated protein folding
GOC52_RS04150	COG0473	3-isopropylmalate dehydrogenase activity
GOC52_RS04220	COG0544	peptidyl-prolyl cis-trans isomerase activity
GOC52_RS04225	COG0740	serine-type endopeptidase activity
GOC52_RS04230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GOC52_RS04270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GOC52_RS04275	COG1388	LysM domain
GOC52_RS04275	COG3942	CHAP domain
GOC52_RS04280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOC52_RS04290	COG0328	RNA-DNA hybrid ribonuclease activity
GOC52_RS04295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GOC52_RS04300	COG0631	protein serine/threonine phosphatase activity
GOC52_RS04315	COG0859	PFAM glycosyl transferase family 9
GOC52_RS04320	COG3642	lipopolysaccharide core region biosynthetic process
GOC52_RS04325	COG1234	tRNA 3'-trailer cleavage
GOC52_RS04340	COG2076	Multidrug Resistance protein
GOC52_RS04355	COG4695	Portal protein
GOC52_RS04380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GOC52_RS04385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GOC52_RS04395	COG0537	adenosine 5'-monophosphoramidase activity
GOC52_RS04415	COG0714	Associated with various cellular activities
GOC52_RS04430	COG1399	metal-binding, possibly nucleic acid-binding protein
GOC52_RS04435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GOC52_RS04440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOC52_RS04450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOC52_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS04465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOC52_RS04470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GOC52_RS04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GOC52_RS04480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GOC52_RS04520	COG4774	siderophore transport
GOC52_RS04530	COG2223	nitrite transmembrane transporter activity
GOC52_RS04545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GOC52_RS04550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOC52_RS04555	COG0697	spore germination
GOC52_RS04560	COG0583	DNA-binding transcription factor activity
GOC52_RS04575	COG2205	protein histidine kinase activity
GOC52_RS04585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS04625	COG0583	DNA-binding transcription factor activity
GOC52_RS04635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GOC52_RS04650	COG0667	Aldo Keto reductase
GOC52_RS04665	COG0456	acetyltransferase
GOC52_RS04675	COG2818	Glycosylase
GOC52_RS04680	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GOC52_RS04685	COG1678	Uncharacterized ACR, COG1678
GOC52_RS04690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GOC52_RS04695	COG0540	Belongs to the ATCase OTCase family
GOC52_RS04715	COG2239	Acts as a magnesium transporter
GOC52_RS04720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GOC52_RS04735	COG1660	Displays ATPase and GTPase activities
GOC52_RS04740	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GOC52_RS04745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOC52_RS04750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GOC52_RS04760	COG1137	ATPase activity
GOC52_RS04775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GOC52_RS04790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GOC52_RS04810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GOC52_RS04830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GOC52_RS04840	COG0628	permease
GOC52_RS04850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GOC52_RS04860	COG2261	transglycosylase associated protein
GOC52_RS04870	COG1555	photosystem II stabilization
GOC52_RS04890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GOC52_RS04895	COG1477	protein flavinylation
GOC52_RS04915	COG4771	TonB-dependent receptor
GOC52_RS04925	COG3128	pkhd-type hydroxylase
GOC52_RS04935	COG4774	siderophore transport
GOC52_RS04945	COG2146	nitrite reductase [NAD(P)H] activity
GOC52_RS05030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GOC52_RS05035	COG0719	Fe-S assembly protein
GOC52_RS05040	COG0396	ATPase activity
GOC52_RS05045	COG0719	Fe-S assembly protein
GOC52_RS05050	COG1959	2 iron, 2 sulfur cluster binding
GOC52_RS05060	COG0693	protein deglycase activity
GOC52_RS05085	COG1764	response to oxidative stress
GOC52_RS05090	COG0384	phenazine biosynthesis protein PhzF
GOC52_RS05095	COG0384	phenazine biosynthesis protein PhzF
GOC52_RS05100	COG0527	aspartate kinase activity
GOC52_RS05110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GOC52_RS05125	COG0142	geranyltranstransferase activity
GOC52_RS05130	COG0366	Alpha amylase catalytic
GOC52_RS05140	COG1082	Xylose isomerase domain protein TIM barrel
GOC52_RS05150	COG2211	Major facilitator Superfamily
GOC52_RS05150	COG2190	(PTS) system
GOC52_RS05175	COG1131	(ABC) transporter
GOC52_RS05250	COG0629	single-stranded DNA binding
GOC52_RS05255	COG0583	DNA-binding transcription factor activity
GOC52_RS05290	COG2010	Cytochrome c
GOC52_RS05305	COG2211	Major facilitator Superfamily
GOC52_RS05315	COG1609	Transcriptional regulator
GOC52_RS05350	COG3655	Transcriptional regulator
GOC52_RS05355	COG1253	flavin adenine dinucleotide binding
GOC52_RS05360	COG1408	metallophosphoesterase
GOC52_RS05365	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GOC52_RS05385	COG2259	Doxx family
GOC52_RS05415	COG0477	Major facilitator Superfamily
GOC52_RS05430	COG1802	Transcriptional regulator
GOC52_RS05465	COG3052	prosthetic group binding
GOC52_RS05480	COG0579	oxidoreductase
GOC52_RS05505	COG3104	oligopeptide transport
GOC52_RS05515	COG1297	OPT oligopeptide transporter protein
GOC52_RS05520	COG0823	Involved in the tonB-independent uptake of proteins
GOC52_RS05520	COG1506	peptidase
GOC52_RS05535	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GOC52_RS05540	COG2894	cell division
GOC52_RS05555	COG4585	Histidine kinase
GOC52_RS05560	COG2197	response regulator
GOC52_RS05595	COG0330	HflC and HflK could
GOC52_RS05600	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GOC52_RS05610	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GOC52_RS05620	COG1595	DNA-templated transcription, initiation
GOC52_RS05630	COG1946	Acyl-CoA thioesterase
GOC52_RS05650	COG0824	Thioesterase
GOC52_RS05655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOC52_RS05660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GOC52_RS05665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GOC52_RS05670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GOC52_RS05675	COG0268	Binds directly to 16S ribosomal RNA
GOC52_RS05680	COG0728	peptidoglycan biosynthetic process
GOC52_RS05685	COG0196	riboflavin kinase activity
GOC52_RS05690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GOC52_RS05700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GOC52_RS05725	COG4206	TonB-dependent receptor
GOC52_RS05745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOC52_RS05775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOC52_RS05780	COG1845	cytochrome c oxidase, subunit III
GOC52_RS05785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GOC52_RS05800	COG0326	Molecular chaperone. Has ATPase activity
GOC52_RS05820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GOC52_RS05835	COG0228	four-way junction DNA binding
GOC52_RS05840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GOC52_RS05845	COG0336	Belongs to the RNA methyltransferase TrmD family
GOC52_RS05850	COG0335	large ribosomal subunit rRNA binding
GOC52_RS05870	COG0534	Mate efflux family protein
GOC52_RS05895	COG0753	catalase activity
GOC52_RS05900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GOC52_RS05930	COG3621	Patatin-like phospholipase
GOC52_RS05940	COG3593	DNA synthesis involved in DNA repair
GOC52_RS06030	COG2200	EAL domain
GOC52_RS06035	COG2186	Transcriptional regulator
GOC52_RS06090	COG1475	DNA binding
GOC52_RS06125	COG0840	transmembrane signaling receptor activity
GOC52_RS06130	COG3134	Outer membrane lipoprotein
GOC52_RS06150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS06175	COG0024	Methionine aminopeptidase
GOC52_RS06200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GOC52_RS06225	COG1647	Serine aminopeptidase, S33
GOC52_RS06250	COG2814	Major facilitator Superfamily
GOC52_RS06255	COG3706	GGDEF domain
GOC52_RS06275	COG0588	phosphoglycerate mutase activity
GOC52_RS06280	COG3590	peptidase
GOC52_RS06290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GOC52_RS06300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GOC52_RS06305	COG0745	RESPONSE REGULATOR receiver
GOC52_RS06310	COG2205	protein histidine kinase activity
GOC52_RS06315	COG4452	Inner membrane protein CreD
GOC52_RS06330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOC52_RS06335	COG0735	belongs to the Fur family
GOC52_RS06415	COG5001	Diguanylate cyclase
GOC52_RS06415	COG5002	protein histidine kinase activity
GOC52_RS06425	COG1187	pseudouridine synthase activity
GOC52_RS06435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GOC52_RS06455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GOC52_RS06460	COG1132	(ABC) transporter
GOC52_RS06525	COG1695	Transcriptional regulator
GOC52_RS06545	COG1981	membrane
GOC52_RS06550	COG0825	malonyl-CoA metabolic process
GOC52_RS06575	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOC52_RS06585	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOC52_RS06595	COG0750	zinc metalloprotease
GOC52_RS06600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GOC52_RS06605	COG0575	Belongs to the CDS family
GOC52_RS06610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GOC52_RS06615	COG0233	cytoplasmic translational termination
GOC52_RS06620	COG0528	UMP kinase activity
GOC52_RS06630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GOC52_RS06635	COG0052	Belongs to the universal ribosomal protein uS2 family
GOC52_RS06655	COG3188	usher protein
GOC52_RS06675	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GOC52_RS06690	COG1393	Belongs to the ArsC family
GOC52_RS06695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOC52_RS06705	COG0367	asparagine synthase
GOC52_RS06710	COG0475	glutathione-regulated potassium exporter activity
GOC52_RS06750	COG1566	PFAM secretion protein HlyD family protein
GOC52_RS06755	COG2814	Major facilitator Superfamily
GOC52_RS06770	COG0583	DNA-binding transcription factor activity
GOC52_RS06790	COG0557	exoribonuclease II activity
GOC52_RS06800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GOC52_RS06805	COG1538	Outer membrane efflux protein
GOC52_RS06810	COG1136	(ABC) transporter
GOC52_RS06810	COG0577	efflux transmembrane transporter activity
GOC52_RS06815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS06835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GOC52_RS06840	COG2259	Doxx family
GOC52_RS06850	COG3220	belongs to the UPF0276 family
GOC52_RS06860	COG0704	Plays a role in the regulation of phosphate uptake
GOC52_RS06870	COG0581	inorganic phosphate transmembrane transporter activity
GOC52_RS06875	COG0573	inorganic phosphate transmembrane transporter activity
GOC52_RS06880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GOC52_RS06885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GOC52_RS06895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GOC52_RS06905	COG1024	Enoyl-CoA hydratase
GOC52_RS06935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GOC52_RS06935	COG0116	Belongs to the methyltransferase superfamily
GOC52_RS06955	COG2733	membrane
GOC52_RS06965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GOC52_RS06970	COG1012	belongs to the aldehyde dehydrogenase family
GOC52_RS06980	COG0477	Major facilitator Superfamily
GOC52_RS06985	COG2703	oxygen carrier activity
GOC52_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GOC52_RS07015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GOC52_RS07020	COG0174	glutamine synthetase
GOC52_RS07030	COG2072	flavoprotein involved in K transport
GOC52_RS07035	COG3842	ATPase activity
GOC52_RS07040	COG1176	ABC-type spermidine putrescine transport system, permease component I
GOC52_RS07045	COG1177	transmembrane transport
GOC52_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
GOC52_RS07065	COG4535	Mg2 and Co2 transporter CorC
GOC52_RS07080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GOC52_RS07085	COG1702	phosphate starvation-inducible protein PhoH
GOC52_RS07095	COG1131	(ABC) transporter
GOC52_RS07100	COG0842	Transport permease protein
GOC52_RS07105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOC52_RS07120	COG0741	lytic transglycosylase activity
GOC52_RS07125	COG0723	plastoquinol--plastocyanin reductase activity
GOC52_RS07130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GOC52_RS07135	COG2857	Cytochrome c1
GOC52_RS07140	COG0625	glutathione transferase activity
GOC52_RS07145	COG2969	positive regulation of protein catabolic process
GOC52_RS07180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GOC52_RS07190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GOC52_RS07205	COG1611	Belongs to the LOG family
GOC52_RS07250	COG0556	nucleotide-excision repair
GOC52_RS07290	COG3713	MltA-interacting MipA family protein
GOC52_RS07310	COG0811	peptide transport
GOC52_RS07315	COG0848	biopolymer transport protein
GOC52_RS07325	COG1663	tetraacyldisaccharide 4'-kinase activity
GOC52_RS07330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GOC52_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GOC52_RS07345	COG0322	excinuclease ABC activity
GOC52_RS07350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOC52_RS07385	COG1136	(ABC) transporter
GOC52_RS07385	COG0577	efflux transmembrane transporter activity
GOC52_RS07570	COG1917	Cupin 2, conserved barrel domain protein
GOC52_RS07570	COG4977	sequence-specific DNA binding
GOC52_RS07575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GOC52_RS07595	COG0348	domain, Protein
GOC52_RS07610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GOC52_RS07625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GOC52_RS07630	COG0069	glutamate synthase activity
GOC52_RS07655	COG1054	Belongs to the UPF0176 family
GOC52_RS07660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOC52_RS07675	COG1253	flavin adenine dinucleotide binding
GOC52_RS07685	COG0306	phosphate transporter
GOC52_RS07695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOC52_RS07710	COG0504	CTP synthase activity
GOC52_RS07715	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GOC52_RS07730	COG0148	phosphopyruvate hydratase activity
GOC52_RS07735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GOC52_RS07740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GOC52_RS07745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GOC52_RS07755	COG2840	Smr protein MutS2
GOC52_RS07760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GOC52_RS07765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GOC52_RS07785	COG1534	Rna-binding protein
GOC52_RS07790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GOC52_RS07795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOC52_RS07805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GOC52_RS07810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GOC52_RS07815	COG1923	regulation of RNA biosynthetic process
GOC52_RS07820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GOC52_RS07825	COG1546	Belongs to the CinA family
GOC52_RS07830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GOC52_RS07835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GOC52_RS07840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GOC52_RS07845	COG2137	regulation of response to DNA damage stimulus
GOC52_RS07850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GOC52_RS07855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GOC52_RS07880	COG4773	Receptor
GOC52_RS07895	COG1940	carbohydrate kinase activity
GOC52_RS07935	COG3540	Alkaline phosphatase
GOC52_RS07950	COG3258	Cytochrome c
GOC52_RS07965	COG2223	nitrite transmembrane transporter activity
GOC52_RS07980	COG1741	Belongs to the pirin family
GOC52_RS07985	COG0583	DNA-binding transcription factor activity
GOC52_RS08010	COG0352	thiamine-phosphate diphosphorylase activity
GOC52_RS08010	COG0351	phosphomethylpyrimidine kinase
GOC52_RS08025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GOC52_RS08030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GOC52_RS08040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOC52_RS08050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GOC52_RS08055	COG0477	Major facilitator Superfamily
GOC52_RS08065	COG0617	tRNA 3'-terminal CCA addition
GOC52_RS08070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GOC52_RS08075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GOC52_RS08080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GOC52_RS08090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GOC52_RS08095	COG0166	Belongs to the GPI family
GOC52_RS08110	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GOC52_RS08120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GOC52_RS08125	COG0671	phosphoesterase, PA-phosphatase related
GOC52_RS08135	COG0800	Aldolase
GOC52_RS08140	COG0129	dihydroxy-acid dehydratase activity
GOC52_RS08150	COG0837	glucose binding
GOC52_RS08155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GOC52_RS08175	COG2009	succinate dehydrogenase
GOC52_RS08180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GOC52_RS08185	COG1053	succinate dehydrogenase
GOC52_RS08205	COG4591	ABC-type transport system involved in lipoprotein release permease component
GOC52_RS08220	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GOC52_RS08230	COG0552	protein localization to endoplasmic reticulum
GOC52_RS08245	COG0742	ribosomal rna small subunit methyltransferase
GOC52_RS08250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GOC52_RS08260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GOC52_RS08265	COG0405	Gamma-glutamyltransferase
GOC52_RS08270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOC52_RS08310	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GOC52_RS08315	COG0415	Belongs to the DNA photolyase family
GOC52_RS08320	COG2885	chlorophyll binding
GOC52_RS08325	COG0583	DNA-binding transcription factor activity
GOC52_RS08395	COG1917	Cupin 2, conserved barrel domain protein
GOC52_RS08395	COG4977	sequence-specific DNA binding
GOC52_RS08420	COG1404	Belongs to the peptidase S8 family
GOC52_RS08455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GOC52_RS08465	COG2914	Belongs to the UPF0125 (RnfH) family
GOC52_RS08470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOC52_RS08475	COG0735	belongs to the Fur family
GOC52_RS08485	COG0583	DNA-binding transcription factor activity
GOC52_RS08490	COG0497	DNA recombination
GOC52_RS08495	COG1420	regulation of RNA biosynthetic process
GOC52_RS08500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GOC52_RS08505	COG0443	Heat shock 70 kDa protein
GOC52_RS08510	COG0484	heat shock protein binding
GOC52_RS08515	COG2207	Transcriptional regulator
GOC52_RS08520	COG2223	nitrite transmembrane transporter activity
GOC52_RS08525	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GOC52_RS08530	COG1605	Chorismate mutase
GOC52_RS08530	COG0287	Prephenate dehydrogenase
GOC52_RS08540	COG1132	(ABC) transporter
GOC52_RS08560	COG5001	Diguanylate cyclase
GOC52_RS08570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GOC52_RS08575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GOC52_RS08580	COG0343	queuine tRNA-ribosyltransferase activity
GOC52_RS08585	COG1862	Preprotein translocase
GOC52_RS08595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOC52_RS08600	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GOC52_RS08610	COG2081	HI0933 family
GOC52_RS08615	COG4681	YaeQ
GOC52_RS08635	COG0625	glutathione transferase activity
GOC52_RS08640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GOC52_RS08645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GOC52_RS08650	COG0513	Belongs to the DEAD box helicase family
GOC52_RS08660	COG0583	DNA-binding transcription factor activity
GOC52_RS08665	COG0488	(ABC) transporter
GOC52_RS08690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS08705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GOC52_RS08710	COG2957	Belongs to the agmatine deiminase family
GOC52_RS08720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GOC52_RS08725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GOC52_RS08735	COG0776	regulation of translation
GOC52_RS08745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GOC52_RS08760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GOC52_RS08765	COG0183	Belongs to the thiolase family
GOC52_RS08770	COG1250	3-hydroxyacyl-CoA dehydrogenase
GOC52_RS08770	COG1024	Enoyl-CoA hydratase
GOC52_RS08780	COG0105	UTP biosynthetic process
GOC52_RS08785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GOC52_RS08795	COG1426	Protein conserved in bacteria
GOC52_RS08800	COG2976	Protein conserved in bacteria
GOC52_RS08805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOC52_RS08810	COG1160	GTP binding
GOC52_RS08820	COG0583	DNA-binding transcription factor activity
GOC52_RS08825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GOC52_RS08830	COG0475	glutathione-regulated potassium exporter activity
GOC52_RS08830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GOC52_RS08850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOC52_RS08850	COG0519	Catalyzes the synthesis of GMP from XMP
GOC52_RS08875	COG0583	DNA-binding transcription factor activity
GOC52_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS08925	COG0596	Alpha beta hydrolase
GOC52_RS08940	COG0640	Transcriptional regulator
GOC52_RS08955	COG4716	Myosin-crossreactive antigen
GOC52_RS08980	COG0431	NADPH-dependent FMN reductase
GOC52_RS08990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOC52_RS08995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOC52_RS09000	COG1473	amidohydrolase
GOC52_RS09010	COG1126	abc transporter atp-binding protein
GOC52_RS09015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GOC52_RS09035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GOC52_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS09060	COG1309	transcriptional regulator
GOC52_RS09075	COG0697	spore germination
GOC52_RS09080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GOC52_RS09085	COG0167	dihydroorotate dehydrogenase activity
GOC52_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS09105	COG1012	belongs to the aldehyde dehydrogenase family
GOC52_RS09120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOC52_RS09155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOC52_RS09185	COG0745	RESPONSE REGULATOR receiver
GOC52_RS09190	COG0784	Response regulator, receiver
GOC52_RS09190	COG4191	Histidine kinase
GOC52_RS09195	COG2205	protein histidine kinase activity
GOC52_RS09195	COG3437	response regulator, receiver
GOC52_RS09195	COG4999	Histidine kinase
GOC52_RS09195	COG3850	Histidine kinase
GOC52_RS09200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GOC52_RS09210	COG5002	protein histidine kinase activity
GOC52_RS09220	COG0640	Transcriptional regulator
GOC52_RS09270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOC52_RS09275	COG0124	histidyl-tRNA synthetase
GOC52_RS09290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GOC52_RS09295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GOC52_RS09300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOC52_RS09305	COG0131	Imidazoleglycerol-phosphate dehydratase
GOC52_RS09305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GOC52_RS09310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GOC52_RS09315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GOC52_RS09320	COG0107	imidazoleglycerol-phosphate synthase activity
GOC52_RS09325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GOC52_RS09325	COG0140	phosphoribosyl-ATP diphosphatase activity
GOC52_RS09345	COG1446	asparaginase
GOC52_RS09350	COG3142	Participates in the control of copper homeostasis
GOC52_RS09365	COG0789	Transcriptional regulator
GOC52_RS09385	COG3537	Alpha-1,2-mannosidase
GOC52_RS09390	COG1609	Transcriptional regulator
GOC52_RS09400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOC52_RS09415	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GOC52_RS09420	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GOC52_RS09425	COG0235	Class ii aldolase
GOC52_RS09430	COG0531	amino acid
GOC52_RS09435	COG0531	amino acid
GOC52_RS09445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GOC52_RS09450	COG0277	FAD linked oxidase domain protein
GOC52_RS09465	COG2205	protein histidine kinase activity
GOC52_RS09470	COG0745	RESPONSE REGULATOR receiver
GOC52_RS09475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS09480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS09495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GOC52_RS09540	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOC52_RS09555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GOC52_RS09560	COG0505	Belongs to the CarA family
GOC52_RS09565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GOC52_RS09570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GOC52_RS09590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GOC52_RS09595	COG4676	Protein conserved in bacteria
GOC52_RS09605	COG3279	Response regulator of the LytR AlgR family
GOC52_RS09620	COG1012	belongs to the aldehyde dehydrogenase family
GOC52_RS09645	COG2205	protein histidine kinase activity
GOC52_RS09645	COG2198	Histidine kinase
GOC52_RS09645	COG0784	Response regulator, receiver
GOC52_RS09650	COG1024	Enoyl-CoA hydratase
GOC52_RS09655	COG0318	PFAM AMP-dependent synthetase and ligase
GOC52_RS09660	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GOC52_RS09665	COG1012	belongs to the aldehyde dehydrogenase family
GOC52_RS09670	COG1309	transcriptional regulator
GOC52_RS09675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GOC52_RS09710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GOC52_RS09720	COG0840	transmembrane signaling receptor activity
GOC52_RS09725	COG0840	transmembrane signaling receptor activity
GOC52_RS09735	COG0835	chemotaxis
GOC52_RS09740	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GOC52_RS09745	COG0840	transmembrane signaling receptor activity
GOC52_RS09755	COG0745	RESPONSE REGULATOR receiver
GOC52_RS09765	COG0835	chemotaxis
GOC52_RS09775	COG1360	Flagellar Motor Protein
GOC52_RS09780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GOC52_RS09785	COG0784	Response regulator, receiver
GOC52_RS09785	COG2198	Histidine kinase
GOC52_RS09785	COG0643	Histidine kinase
GOC52_RS09790	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GOC52_RS09815	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GOC52_RS09820	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GOC52_RS09835	COG1987	bacterial-type flagellum assembly
GOC52_RS09845	COG3190	flagellar
GOC52_RS09895	COG1677	Flagellar hook-basal body complex protein FliE
GOC52_RS09915	COG2197	response regulator
GOC52_RS09935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GOC52_RS09975	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GOC52_RS09985	COG4787	bacterial-type flagellum-dependent cell motility
GOC52_RS10000	COG1558	bacterial-type flagellum-dependent cell motility
GOC52_RS10005	COG1815	bacterial-type flagellum-dependent cell motility
GOC52_RS10010	COG0835	chemotaxis
GOC52_RS10010	COG0784	Response regulator, receiver
GOC52_RS10030	COG5002	protein histidine kinase activity
GOC52_RS10065	COG2915	High frequency lysogenization protein hflD homolog
GOC52_RS10070	COG0482	sulfurtransferase activity
GOC52_RS10085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GOC52_RS10095	COG0542	response to heat
GOC52_RS10130	COG0492	ferredoxin-NADP+ reductase activity
GOC52_RS10135	COG1674	ftsk spoiiie
GOC52_RS10145	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GOC52_RS10150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GOC52_RS10165	COG2819	hydrolase of the alpha beta superfamily
GOC52_RS10175	COG4558	Periplasmic binding protein
GOC52_RS10180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOC52_RS10185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GOC52_RS10195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GOC52_RS10210	COG5002	protein histidine kinase activity
GOC52_RS10210	COG0784	Response regulator, receiver
GOC52_RS10245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GOC52_RS10255	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GOC52_RS10270	COG1595	DNA-templated transcription, initiation
GOC52_RS10290	COG0784	Response regulator, receiver
GOC52_RS10295	COG4251	negative regulation of phosphorylation
GOC52_RS10305	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GOC52_RS10350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GOC52_RS10355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GOC52_RS10360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GOC52_RS10365	COG2080	2 iron, 2 sulfur cluster binding
GOC52_RS10385	COG0583	DNA-binding transcription factor activity
GOC52_RS10405	COG1595	DNA-templated transcription, initiation
GOC52_RS10410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOC52_RS10490	COG3685	Protein conserved in bacteria
GOC52_RS10515	COG3546	catalase activity
GOC52_RS10520	COG3685	Protein conserved in bacteria
GOC52_RS10540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GOC52_RS10560	COG1063	alcohol dehydrogenase
GOC52_RS10590	COG1609	Transcriptional regulator
GOC52_RS10595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOC52_RS10595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GOC52_RS10600	COG1105	Belongs to the carbohydrate kinase PfkB family
GOC52_RS10605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOC52_RS10605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOC52_RS10625	COG2211	Major facilitator Superfamily
GOC52_RS10630	COG1472	Belongs to the glycosyl hydrolase 3 family
GOC52_RS10645	COG3661	Belongs to the glycosyl hydrolase 67 family
GOC52_RS10655	COG1472	Belongs to the glycosyl hydrolase 3 family
GOC52_RS10660	COG0477	Major facilitator Superfamily
GOC52_RS10670	COG1070	Carbohydrate kinase
GOC52_RS10695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GOC52_RS10720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GOC52_RS10735	COG2828	Protein conserved in bacteria
GOC52_RS10740	COG0583	DNA-binding transcription factor activity
GOC52_RS10760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GOC52_RS10765	COG0583	DNA-binding transcription factor activity
GOC52_RS10780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GOC52_RS10815	COG0642	Histidine kinase
GOC52_RS10825	COG0318	PFAM AMP-dependent synthetase and ligase
GOC52_RS10835	COG5265	(ABC) transporter
GOC52_RS10880	COG2186	Transcriptional regulator
GOC52_RS10900	COG2271	Major facilitator Superfamily
GOC52_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS10940	COG1404	Belongs to the peptidase S8 family
GOC52_RS10955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOC52_RS10980	COG0583	DNA-binding transcription factor activity
GOC52_RS11005	COG2204	response regulator
GOC52_RS11070	COG3447	MASE1 domain protein
GOC52_RS11070	COG5002	protein histidine kinase activity
GOC52_RS11070	COG5001	Diguanylate cyclase
GOC52_RS11075	COG1136	(ABC) transporter
GOC52_RS11075	COG0577	efflux transmembrane transporter activity
GOC52_RS11080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS11090	COG0745	RESPONSE REGULATOR receiver
GOC52_RS11095	COG2205	protein histidine kinase activity
GOC52_RS11105	COG3214	Protein conserved in bacteria
GOC52_RS11115	COG4774	siderophore transport
GOC52_RS11140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GOC52_RS11145	COG1285	pathogenesis
GOC52_RS11150	COG4191	Histidine kinase
GOC52_RS11155	COG4566	intracellular signal transduction
GOC52_RS11225	COG0477	Major facilitator Superfamily
GOC52_RS11250	COG1136	(ABC) transporter
GOC52_RS11265	COG0583	DNA-binding transcription factor activity
GOC52_RS11305	COG5002	protein histidine kinase activity
GOC52_RS11310	COG0583	DNA-binding transcription factor activity
GOC52_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS11340	COG0642	Histidine kinase
GOC52_RS11345	COG3537	Alpha-1,2-mannosidase
GOC52_RS11350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS11365	COG0477	Major facilitator Superfamily
GOC52_RS11380	COG2202	Pas domain
GOC52_RS11380	COG3920	Histidine kinase
GOC52_RS11430	COG1335	isochorismatase
GOC52_RS11435	COG1335	isochorismatase
GOC52_RS11465	COG0811	peptide transport
GOC52_RS11595	COG0840	transmembrane signaling receptor activity
GOC52_RS11610	COG4149	molybdate abc transporter
GOC52_RS11615	COG0725	ABC transporter, periplasmic molybdate-binding protein
GOC52_RS11620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOC52_RS11635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GOC52_RS11640	COG2181	nitrate reductase activity
GOC52_RS11645	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GOC52_RS11650	COG1140	nitrate reductase beta subunit
GOC52_RS11655	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GOC52_RS11660	COG2223	nitrite transmembrane transporter activity
GOC52_RS11670	COG0746	molybdenum cofactor guanylyltransferase activity
GOC52_RS11675	COG0314	molybdopterin synthase activity
GOC52_RS11685	COG0303	'Molybdopterin
GOC52_RS11690	COG0315	cyclic pyranopterin monophosphate synthase activity
GOC52_RS11690	COG0521	Mo-molybdopterin cofactor biosynthetic process
GOC52_RS11695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GOC52_RS11735	COG2207	Transcriptional regulator
GOC52_RS11790	COG2205	protein histidine kinase activity
GOC52_RS11800	COG2194	sulfuric ester hydrolase activity
GOC52_RS11820	COG2885	chlorophyll binding
GOC52_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS11845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOC52_RS11845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GOC52_RS11855	COG3433	isochorismatase activity
GOC52_RS11855	COG1535	isochorismatase
GOC52_RS11860	COG1021	2,3-dihydroxybenzoate-AMP ligase
GOC52_RS11875	COG2409	Drug exporters of the RND superfamily
GOC52_RS11880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOC52_RS11945	COG1914	H( )-stimulated, divalent metal cation uptake system
GOC52_RS11960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOC52_RS11965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOC52_RS11970	COG0604	alcohol dehydrogenase
GOC52_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS11970	COG3321	synthase
GOC52_RS11975	COG4206	TonB-dependent receptor
GOC52_RS11980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GOC52_RS12015	COG0583	DNA-binding transcription factor activity
GOC52_RS12025	COG4772	TonB-dependent receptor
GOC52_RS12045	COG2226	methyltransferase
GOC52_RS12090	COG4964	Belongs to the GSP D family
GOC52_RS12145	COG2814	Major facilitator Superfamily
GOC52_RS12155	COG1228	amidohydrolase
GOC52_RS12165	COG1335	isochorismatase
GOC52_RS12180	COG3850	Histidine kinase
GOC52_RS12185	COG2197	response regulator
GOC52_RS12190	COG2814	Major facilitator Superfamily
GOC52_RS12210	COG0583	DNA-binding transcription factor activity
GOC52_RS12225	COG3161	chorismate lyase activity
GOC52_RS12265	COG0277	FAD linked oxidase domain protein
GOC52_RS12270	COG1304	FMN binding
GOC52_RS12275	COG2186	Transcriptional regulator
GOC52_RS12285	COG1285	pathogenesis
GOC52_RS12310	COG2814	Major facilitator Superfamily
GOC52_RS12365	COG0587	DNA-directed DNA polymerase activity
GOC52_RS12380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GOC52_RS12385	COG0519	Catalyzes the synthesis of GMP from XMP
GOC52_RS12385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOC52_RS12400	COG1595	DNA-templated transcription, initiation
GOC52_RS12410	COG4206	TonB-dependent receptor
GOC52_RS12410	COG1629	transport
GOC52_RS12440	COG0531	amino acid
GOC52_RS12455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS12465	COG0789	Transcriptional regulator
GOC52_RS12530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GOC52_RS12560	COG5001	Diguanylate cyclase
GOC52_RS12560	COG3447	MASE1 domain protein
GOC52_RS12560	COG5002	protein histidine kinase activity
GOC52_RS12565	COG2183	response to ionizing radiation
GOC52_RS12595	COG3243	poly(R)-hydroxyalkanoic acid synthase
GOC52_RS12615	COG0534	Mate efflux family protein
GOC52_RS12635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GOC52_RS12645	COG0668	transmembrane transport
GOC52_RS12650	COG1902	pentaerythritol trinitrate reductase activity
GOC52_RS12660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GOC52_RS12670	COG1733	regulation of RNA biosynthetic process
GOC52_RS12675	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOC52_RS12680	COG0456	acetyltransferase
GOC52_RS12760	COG3702	type iv secretory pathway
GOC52_RS12780	COG2948	multi-organism process
GOC52_RS12790	COG3736	Type IV secretory pathway, component VirB8
GOC52_RS12810	COG2814	Major facilitator Superfamily
GOC52_RS12815	COG0789	Transcriptional regulator
GOC52_RS12845	COG0784	Response regulator, receiver
GOC52_RS12845	COG4191	Histidine kinase
GOC52_RS12860	COG4774	siderophore transport
GOC52_RS12870	COG0745	RESPONSE REGULATOR receiver
GOC52_RS12890	COG1136	(ABC) transporter
GOC52_RS12890	COG0577	efflux transmembrane transporter activity
GOC52_RS12910	COG1733	regulation of RNA biosynthetic process
GOC52_RS12915	COG0604	alcohol dehydrogenase
GOC52_RS12925	COG0210	DNA helicase
GOC52_RS12940	COG0583	DNA-binding transcription factor activity
GOC52_RS12945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GOC52_RS12955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GOC52_RS12970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GOC52_RS12975	COG0077	Prephenate dehydratase
GOC52_RS12975	COG1605	Chorismate mutase
GOC52_RS12980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GOC52_RS13015	COG1228	amidohydrolase
GOC52_RS13030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GOC52_RS13070	COG2957	Belongs to the agmatine deiminase family
GOC52_RS13075	COG0583	DNA-binding transcription factor activity
GOC52_RS13140	COG4993	Dehydrogenase
GOC52_RS13150	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GOC52_RS13160	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GOC52_RS13170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GOC52_RS13175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOC52_RS13190	COG0359	binds to the 23S rRNA
GOC52_RS13195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GOC52_RS13200	COG0360	Binds together with S18 to 16S ribosomal RNA
GOC52_RS13205	COG0316	Belongs to the HesB IscA family
GOC52_RS13210	COG0017	Asparaginyl-tRNA synthetase
GOC52_RS13230	COG0288	reversible hydration of carbon dioxide
GOC52_RS13240	COG3844	kynureninase activity
GOC52_RS13245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GOC52_RS13250	COG2925	Exonuclease
GOC52_RS13260	COG0667	Aldo Keto reductase
GOC52_RS13285	COG2902	Dehydrogenase
GOC52_RS13295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS13300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS13310	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS13325	COG0646	methionine synthase
GOC52_RS13325	COG1410	methionine synthase
GOC52_RS13335	COG2755	lipolytic protein G-D-S-L family
GOC52_RS13335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOC52_RS13345	COG2900	Belongs to the SlyX family
GOC52_RS13360	COG0386	Belongs to the glutathione peroxidase family
GOC52_RS13365	COG1725	Transcriptional regulator
GOC52_RS13370	COG1131	(ABC) transporter
GOC52_RS13410	COG2850	peptidyl-arginine hydroxylation
GOC52_RS13420	COG0567	Dehydrogenase, E1 component
GOC52_RS13445	COG3540	Alkaline phosphatase
GOC52_RS13455	COG0305	Participates in initiation and elongation during chromosome replication
GOC52_RS13475	COG0625	glutathione transferase activity
GOC52_RS13495	COG0084	hydrolase, TatD family'
GOC52_RS13500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GOC52_RS13535	COG0625	glutathione transferase activity
GOC52_RS13555	COG1595	DNA-templated transcription, initiation
GOC52_RS13560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GOC52_RS13575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS13580	COG0386	Belongs to the glutathione peroxidase family
GOC52_RS13585	COG0339	signal peptide processing
GOC52_RS13590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GOC52_RS13610	COG0705	Rhomboid family
GOC52_RS13615	COG3104	oligopeptide transport
GOC52_RS13625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GOC52_RS13630	COG4290	ribonuclease
GOC52_RS13645	COG0316	Belongs to the HesB IscA family
GOC52_RS13645	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GOC52_RS13650	COG2154	pterin-4-alpha-carbinolamine dehydratase
GOC52_RS13660	COG0428	transporter
GOC52_RS13670	COG1530	ribonuclease E activity
GOC52_RS13685	COG0395	ABC-type sugar transport system, permease component
GOC52_RS13710	COG1609	Transcriptional regulator
GOC52_RS13715	COG0271	Belongs to the BolA IbaG family
GOC52_RS13720	COG2350	Protein conserved in bacteria
GOC52_RS13725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GOC52_RS13730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GOC52_RS13735	COG1187	pseudouridine synthase activity
GOC52_RS13745	COG2814	Major facilitator Superfamily
GOC52_RS13765	COG0436	Aminotransferase
GOC52_RS13770	COG4133	protoheme IX ABC transporter activity
GOC52_RS13790	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GOC52_RS13805	COG4235	cytochrome complex assembly
GOC52_RS13805	COG3088	subunit of a heme lyase
GOC52_RS13815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GOC52_RS13825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GOC52_RS13830	COG4988	ABC transporter
GOC52_RS13840	COG1294	oxidase, subunit
GOC52_RS13870	COG0726	polysaccharide deacetylase
GOC52_RS13870	COG1649	PFAM Uncharacterised BCR, COG1649
GOC52_RS13875	COG1215	transferase activity, transferring glycosyl groups
GOC52_RS13885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GOC52_RS13900	COG0165	Argininosuccinate lyase
GOC52_RS13905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GOC52_RS13915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GOC52_RS13920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOC52_RS13925	COG0137	argininosuccinate synthase activity
GOC52_RS13930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GOC52_RS13945	COG2166	iron-sulfur cluster assembly
GOC52_RS13965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GOC52_RS13985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GOC52_RS13990	COG0402	S-adenosylhomocysteine deaminase activity
GOC52_RS13995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GOC52_RS14000	COG1509	lysine 2,3-aminomutase activity
GOC52_RS14005	COG3300	MHYT domain
GOC52_RS14005	COG5001	Diguanylate cyclase
GOC52_RS14025	COG0501	Belongs to the peptidase M48B family
GOC52_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS14055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GOC52_RS14060	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOC52_RS14065	COG0802	atpase or kinase
GOC52_RS14070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GOC52_RS14070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GOC52_RS14075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GOC52_RS14080	COG1570	exodeoxyribonuclease VII activity
GOC52_RS14090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GOC52_RS14110	COG4771	TonB-dependent receptor
GOC52_RS14115	COG1309	transcriptional regulator
GOC52_RS14155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GOC52_RS14155	COG2169	Transcriptional regulator
GOC52_RS14160	COG2130	NADP-dependent
GOC52_RS14185	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS14195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GOC52_RS14225	COG1309	transcriptional regulator
GOC52_RS14230	COG2076	Multidrug Resistance protein
GOC52_RS14235	COG5487	UPF0391 membrane protein
GOC52_RS14240	COG1280	lysine exporter protein (LysE YggA)
GOC52_RS14250	COG1794	racemase activity, acting on amino acids and derivatives
GOC52_RS14270	COG0456	acetyltransferase
GOC52_RS14270	COG0454	-acetyltransferase
GOC52_RS14285	COG0776	regulation of translation
GOC52_RS14290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOC52_RS14290	COG0072	phenylalanine-tRNA ligase activity
GOC52_RS14295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GOC52_RS14300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GOC52_RS14305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GOC52_RS14310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GOC52_RS14315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GOC52_RS14350	COG1185	polyribonucleotide nucleotidyltransferase activity
GOC52_RS14355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GOC52_RS14360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GOC52_RS14365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GOC52_RS14370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GOC52_RS14375	COG0195	Participates in both transcription termination and antitermination
GOC52_RS14380	COG0779	Required for maturation of 30S ribosomal subunits
GOC52_RS14395	COG1007	ATP synthesis coupled electron transport
GOC52_RS14410	COG0713	ATP synthesis coupled electron transport
GOC52_RS14420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOC52_RS14425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GOC52_RS14440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GOC52_RS14445	COG0649	NAD binding
GOC52_RS14450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOC52_RS14455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOC52_RS14460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOC52_RS14475	COG0149	triose-phosphate isomerase activity
GOC52_RS14490	COG3119	arylsulfatase activity
GOC52_RS14495	COG0438	transferase activity, transferring glycosyl groups
GOC52_RS14500	COG0726	polysaccharide deacetylase
GOC52_RS14505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOC52_RS14510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GOC52_RS14515	COG0159	tryptophan synthase activity
GOC52_RS14525	COG0133	tryptophan synthase activity
GOC52_RS14535	COG3409	Peptidoglycan-binding domain 1 protein
GOC52_RS14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOC52_RS14545	COG0135	phosphoribosylanthranilate isomerase activity
GOC52_RS14550	COG0101	tRNA pseudouridine synthase activity
GOC52_RS14565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GOC52_RS14570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOC52_RS14575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GOC52_RS14580	COG2890	protein-(glutamine-N5) methyltransferase activity
GOC52_RS14585	COG1999	signal sequence binding
GOC52_RS14590	COG0688	phosphatidylethanolamine metabolic process
GOC52_RS14605	COG0433	COG0433 Predicted ATPase
GOC52_RS14610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GOC52_RS14620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOC52_RS14625	COG0412	Dienelactone hydrolase
GOC52_RS14640	COG0717	Belongs to the dCTP deaminase family
GOC52_RS14645	COG0489	protein tyrosine kinase activity
GOC52_RS14650	COG4771	TonB-dependent receptor
GOC52_RS14655	COG4771	TonB-dependent receptor
GOC52_RS14665	COG4771	TonB-dependent receptor
GOC52_RS14670	COG3590	peptidase
GOC52_RS14700	COG0697	spore germination
GOC52_RS14710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GOC52_RS14715	COG2311	Membrane
GOC52_RS14720	COG1047	Peptidyl-prolyl cis-trans
GOC52_RS14725	COG0791	NLP P60 protein
GOC52_RS14730	COG0791	NLP P60 protein
GOC52_RS14735	COG1301	dicarboxylic acid transport
GOC52_RS14755	COG1722	exodeoxyribonuclease VII activity
GOC52_RS14760	COG0142	geranyltranstransferase activity
GOC52_RS14770	COG0312	modulator of DNA gyrase
GOC52_RS14775	COG3028	Belongs to the UPF0307 family
GOC52_RS14780	COG0312	modulator of DNA gyrase
GOC52_RS14800	COG2968	Membrane
GOC52_RS14810	COG4771	TonB-dependent receptor
GOC52_RS14825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GOC52_RS14835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GOC52_RS14850	COG0495	leucyl-tRNA aminoacylation
GOC52_RS14860	COG3118	belongs to the thioredoxin family
GOC52_RS14870	COG4251	negative regulation of phosphorylation
GOC52_RS14870	COG3706	GGDEF domain
GOC52_RS14870	COG2203	Gaf domain
GOC52_RS14870	COG5001	Diguanylate cyclase
GOC52_RS14895	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GOC52_RS14905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GOC52_RS14910	COG0346	lactoylglutathione lyase activity
GOC52_RS14920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOC52_RS14920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOC52_RS14930	COG2878	Part of a membrane complex involved in electron transport
GOC52_RS14935	COG0251	oxidation-reduction process
GOC52_RS14940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GOC52_RS14940	COG0392	lysyltransferase activity
GOC52_RS14970	COG2824	Alkylphosphonate utilization operon protein PhnA
GOC52_RS14975	COG0443	Heat shock 70 kDa protein
GOC52_RS15015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GOC52_RS15020	COG3122	Protein conserved in bacteria
GOC52_RS15025	COG1451	nucleotide metabolic process
GOC52_RS15035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOC52_RS15055	COG0183	Belongs to the thiolase family
GOC52_RS15070	COG1960	acyl-CoA dehydrogenase activity
GOC52_RS15080	COG1793	dna ligase
GOC52_RS15085	COG1201	RNA secondary structure unwinding
GOC52_RS15100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GOC52_RS15105	COG1278	Cold shock
GOC52_RS15110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GOC52_RS15115	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GOC52_RS15120	COG1472	Belongs to the glycosyl hydrolase 3 family
GOC52_RS15125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GOC52_RS15130	COG2954	triphosphatase activity
GOC52_RS15135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GOC52_RS15140	COG0745	RESPONSE REGULATOR receiver
GOC52_RS15145	COG1381	Involved in DNA repair and RecF pathway recombination
GOC52_RS15150	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GOC52_RS15165	COG0681	Belongs to the peptidase S26 family
GOC52_RS15170	COG0481	GTPase activity
GOC52_RS15175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOC52_RS15200	COG1741	Belongs to the pirin family
GOC52_RS15205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GOC52_RS15215	COG1741	Belongs to the pirin family
GOC52_RS15220	COG1966	Carbon starvation protein
GOC52_RS15225	COG2879	small protein
GOC52_RS15240	COG2205	protein histidine kinase activity
GOC52_RS15245	COG0745	RESPONSE REGULATOR receiver
GOC52_RS15280	COG2814	Major facilitator Superfamily
GOC52_RS15285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOC52_RS15285	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOC52_RS15295	COG1113	amino acid transport
GOC52_RS15300	COG1917	Cupin 2, conserved barrel domain protein
GOC52_RS15300	COG2207	Transcriptional regulator
GOC52_RS15305	COG0753	catalase activity
GOC52_RS15320	COG1376	ErfK ybiS ycfS ynhG family protein
GOC52_RS15325	COG0739	heme binding
GOC52_RS15335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GOC52_RS15345	COG0330	HflC and HflK could
GOC52_RS15350	COG0330	HflC and HflK could
GOC52_RS15355	COG0604	alcohol dehydrogenase
GOC52_RS15370	COG0678	peroxiredoxin activity
GOC52_RS15380	COG4953	penicillin-binding protein 1C
GOC52_RS15385	COG2373	Large extracellular alpha-helical protein
GOC52_RS15390	COG2079	MmgE PrpD family protein
GOC52_RS15395	COG2828	Protein conserved in bacteria
GOC52_RS15415	COG3829	transcription factor binding
GOC52_RS15420	COG0259	pyridoxamine-phosphate oxidase activity
GOC52_RS15435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GOC52_RS15455	COG0477	Major facilitator Superfamily
GOC52_RS15460	COG0784	Response regulator, receiver
GOC52_RS15460	COG2198	Histidine kinase
GOC52_RS15460	COG5002	protein histidine kinase activity
GOC52_RS15465	COG5002	protein histidine kinase activity
GOC52_RS15465	COG0784	Response regulator, receiver
GOC52_RS15475	COG3038	cytochrome b561
GOC52_RS15490	COG1760	l-serine dehydratase
GOC52_RS15500	COG0460	homoserine dehydrogenase
GOC52_RS15500	COG0527	aspartate kinase activity
GOC52_RS15505	COG0626	cystathionine gamma-synthase activity
GOC52_RS15510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GOC52_RS15515	COG0739	heme binding
GOC52_RS15520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GOC52_RS15525	COG1272	protein, Hemolysin III
GOC52_RS15530	COG2982	Protein involved in outer membrane biogenesis
GOC52_RS15540	COG0463	Glycosyl transferase, family 2
GOC52_RS15545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOC52_RS15550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GOC52_RS15565	COG1309	transcriptional regulator
GOC52_RS15610	COG0583	DNA-binding transcription factor activity
GOC52_RS15625	COG0509	glycine decarboxylation via glycine cleavage system
GOC52_RS15630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GOC52_RS15640	COG0330	HflC and HflK could
GOC52_RS15650	COG1742	UPF0060 membrane protein
GOC52_RS15655	COG3956	TIGRFAM MazG family protein
GOC52_RS15660	COG1218	3'(2'),5'-bisphosphate nucleotidase
GOC52_RS15665	COG0494	nUDIX hydrolase
GOC52_RS15675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GOC52_RS15690	COG0784	Response regulator, receiver
GOC52_RS15690	COG0643	Histidine kinase
GOC52_RS15690	COG2198	Histidine kinase
GOC52_RS15695	COG0840	transmembrane signaling receptor activity
GOC52_RS15700	COG0835	chemotaxis
GOC52_RS15715	COG0189	ligase activity
GOC52_RS15730	COG1199	ATP-dependent helicase activity
GOC52_RS15740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOC52_RS15745	COG1216	Glycosyl transferase, family 2
GOC52_RS15755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GOC52_RS15765	COG1643	Atp-dependent helicase
GOC52_RS15770	COG0783	Belongs to the Dps family
GOC52_RS15775	COG0514	ATP-dependent DNA helicase (RecQ)
GOC52_RS15870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GOC52_RS15875	COG0602	queuosine metabolic process
GOC52_RS15885	COG2885	chlorophyll binding
GOC52_RS15890	COG0823	Involved in the tonB-independent uptake of proteins
GOC52_RS15905	COG0811	peptide transport
GOC52_RS15910	COG0824	Thioesterase
GOC52_RS15915	COG2255	four-way junction helicase activity
GOC52_RS15925	COG0632	four-way junction helicase activity
GOC52_RS15930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GOC52_RS15935	COG0217	transcriptional regulatory protein
GOC52_RS15955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GOC52_RS15985	COG0488	(ABC) transporter
GOC52_RS16005	COG4651	solute:proton antiporter activity
GOC52_RS16005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GOC52_RS16020	COG0745	RESPONSE REGULATOR receiver
GOC52_RS16025	COG2205	protein histidine kinase activity
GOC52_RS16040	COG0542	response to heat
GOC52_RS16060	COG0028	Belongs to the TPP enzyme family
GOC52_RS16085	COG3387	PFAM Glycoside hydrolase 15-related
GOC52_RS16090	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GOC52_RS16095	COG3011	Protein conserved in bacteria
GOC52_RS16110	COG0564	pseudouridine synthase activity
GOC52_RS16115	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOC52_RS16125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GOC52_RS16125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GOC52_RS16135	COG0045	succinate-CoA ligase (ADP-forming) activity
GOC52_RS16170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GOC52_RS16185	COG2205	protein histidine kinase activity
GOC52_RS16190	COG0745	RESPONSE REGULATOR receiver
GOC52_RS16205	COG0189	ligase activity
GOC52_RS16225	COG3152	Membrane
GOC52_RS16240	COG3240	lipase activity
GOC52_RS16240	COG4625	pathogenesis
GOC52_RS16250	COG2022	thiamine diphosphate biosynthetic process
GOC52_RS16255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GOC52_RS16260	COG3273	potassium ion transport
GOC52_RS16260	COG0471	metal ion transport
GOC52_RS16280	COG1970	mechanosensitive ion channel activity
GOC52_RS16295	COG1115	amino acid carrier protein
GOC52_RS16305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS16310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS16335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GOC52_RS16345	COG3588	fructose-bisphosphate aldolase
GOC52_RS16350	COG0469	pyruvate kinase activity
GOC52_RS16360	COG0126	phosphoglycerate kinase activity
GOC52_RS16375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GOC52_RS16380	COG3047	cAMP biosynthetic process
GOC52_RS16425	COG3093	addiction module antidote protein HigA
GOC52_RS16435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GOC52_RS16440	COG1301	dicarboxylic acid transport
GOC52_RS16450	COG2304	oxidoreductase activity
GOC52_RS16470	COG0714	Associated with various cellular activities
GOC52_RS16500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GOC52_RS16515	COG5295	Hep Hag repeat protein
GOC52_RS16555	COG0254	rRNA binding
GOC52_RS16565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GOC52_RS16575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GOC52_RS16580	COG1758	RNA polymerase activity
GOC52_RS16595	COG0437	4 iron, 4 sulfur cluster binding
GOC52_RS16600	COG2864	formate dehydrogenase
GOC52_RS16610	COG1921	L-seryl-tRNASec selenium transferase activity
GOC52_RS16615	COG3276	selenocysteine insertion sequence binding
GOC52_RS16625	COG0709	Synthesizes selenophosphate from selenide and ATP
GOC52_RS16630	COG1561	YicC-like family, N-terminal region
GOC52_RS16635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GOC52_RS16640	COG0346	lactoylglutathione lyase activity
GOC52_RS16650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GOC52_RS16665	COG0006	proline dipeptidase activity
GOC52_RS16670	COG0006	proline dipeptidase activity
GOC52_RS16675	COG3079	Belongs to the UPF0149 family
GOC52_RS16695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GOC52_RS16705	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GOC52_RS16715	COG2912	Transglutaminase-like superfamily
GOC52_RS16720	COG1773	rubredoxin
GOC52_RS16730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GOC52_RS16735	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GOC52_RS16745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOC52_RS16750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOC52_RS16765	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS16790	COG0671	phosphoesterase, PA-phosphatase related
GOC52_RS16800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GOC52_RS16805	COG0563	adenylate kinase activity
GOC52_RS16830	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GOC52_RS16840	COG0848	biopolymer transport protein
GOC52_RS16850	COG2832	Protein of unknown function (DUF454)
GOC52_RS16885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GOC52_RS16910	COG0745	RESPONSE REGULATOR receiver
GOC52_RS16920	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GOC52_RS16925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GOC52_RS16930	COG0405	Gamma-glutamyltransferase
GOC52_RS16935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GOC52_RS16955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOC52_RS16960	COG2226	methyltransferase
GOC52_RS16975	COG0473	3-isopropylmalate dehydrogenase activity
GOC52_RS16990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS17010	COG1538	Outer membrane efflux protein
GOC52_RS17015	COG0531	amino acid
GOC52_RS17020	COG1519	Transferase
GOC52_RS17025	COG1560	Kdo2-lipid A biosynthetic process
GOC52_RS17060	COG1301	dicarboxylic acid transport
GOC52_RS17070	COG4191	Histidine kinase
GOC52_RS17090	COG0642	Histidine kinase
GOC52_RS17105	COG2851	Citrate transporter
GOC52_RS17110	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS17130	COG1162	GTPase activity
GOC52_RS17135	COG0436	Aminotransferase
GOC52_RS17145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GOC52_RS17155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GOC52_RS17170	COG1228	amidohydrolase
GOC52_RS17175	COG0804	urea catabolic process
GOC52_RS17185	COG1307	EDD domain protein, DegV family
GOC52_RS17225	COG3706	GGDEF domain
GOC52_RS17225	COG4251	negative regulation of phosphorylation
GOC52_RS17225	COG5001	Diguanylate cyclase
GOC52_RS17225	COG2203	Gaf domain
GOC52_RS17230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GOC52_RS17240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GOC52_RS17250	COG4206	TonB-dependent receptor
GOC52_RS17260	COG1902	pentaerythritol trinitrate reductase activity
GOC52_RS17280	COG0583	DNA-binding transcription factor activity
GOC52_RS17285	COG1064	alcohol dehydrogenase
GOC52_RS17305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GOC52_RS17310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GOC52_RS17325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GOC52_RS17340	COG1522	sequence-specific DNA binding
GOC52_RS17350	COG4773	Receptor
GOC52_RS17380	COG0617	tRNA 3'-terminal CCA addition
GOC52_RS17400	COG3468	outer membrane autotransporter barrel domain protein
GOC52_RS17410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GOC52_RS17415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GOC52_RS17420	COG1609	Transcriptional regulator
GOC52_RS17430	COG0837	glucose binding
GOC52_RS17440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOC52_RS17460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GOC52_RS17470	COG4191	Histidine kinase
GOC52_RS17475	COG0784	Response regulator, receiver
GOC52_RS17480	COG4251	negative regulation of phosphorylation
GOC52_RS17485	COG2823	Periplasmic or secreted lipoprotein
GOC52_RS17490	COG0673	inositol 2-dehydrogenase activity
GOC52_RS17495	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GOC52_RS17515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GOC52_RS17520	COG0321	lipoyl(octanoyl) transferase activity
GOC52_RS17525	COG2921	Belongs to the UPF0250 family
GOC52_RS17535	COG1686	Belongs to the peptidase S11 family
GOC52_RS17540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GOC52_RS17545	COG2951	lytic endotransglycosylase activity
GOC52_RS17555	COG0772	Belongs to the SEDS family
GOC52_RS17560	COG0772	Belongs to the SEDS family
GOC52_RS17565	COG0768	penicillin binding
GOC52_RS17575	COG1792	Involved in formation and maintenance of cell shape
GOC52_RS17580	COG1077	Cell shape determining protein MreB Mrl
GOC52_RS17585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOC52_RS17600	COG0308	aminopeptidase N
GOC52_RS17605	COG2226	methyltransferase
GOC52_RS17630	COG1943	Transposase
GOC52_RS17640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS17645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS17655	COG0673	inositol 2-dehydrogenase activity
GOC52_RS17665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GOC52_RS17685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GOC52_RS17695	COG2832	Protein of unknown function (DUF454)
GOC52_RS17705	COG0436	Aminotransferase
GOC52_RS17710	COG1505	serine-type exopeptidase activity
GOC52_RS17735	COG0697	spore germination
GOC52_RS17740	COG1666	GTP binding
GOC52_RS17770	COG0339	signal peptide processing
GOC52_RS17780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GOC52_RS17800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GOC52_RS17810	COG1136	(ABC) transporter
GOC52_RS17815	COG1136	(ABC) transporter
GOC52_RS17815	COG0577	efflux transmembrane transporter activity
GOC52_RS17820	COG0577	efflux transmembrane transporter activity
GOC52_RS17830	COG2204	response regulator
GOC52_RS17835	COG4191	Histidine kinase
GOC52_RS17845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GOC52_RS17865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GOC52_RS17870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GOC52_RS17875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GOC52_RS17880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GOC52_RS17885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GOC52_RS17890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GOC52_RS17900	COG0356	it plays a direct role in the translocation of protons across the membrane
GOC52_RS17915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOC52_RS17920	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOC52_RS17940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GOC52_RS17965	COG0181	hydroxymethylbilane synthase activity
GOC52_RS17975	COG2972	Histidine kinase
GOC52_RS17975	COG0745	RESPONSE REGULATOR receiver
GOC52_RS17990	COG4771	TonB-dependent receptor
GOC52_RS18005	COG0840	transmembrane signaling receptor activity
GOC52_RS18070	COG0583	DNA-binding transcription factor activity
GOC52_RS18075	COG0477	Major facilitator Superfamily
GOC52_RS18110	COG0625	glutathione transferase activity
GOC52_RS18115	COG2259	Doxx family
GOC52_RS18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOC52_RS18165	COG1490	D-aminoacyl-tRNA deacylase activity
GOC52_RS18210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOC52_RS18210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GOC52_RS18215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GOC52_RS18220	COG0242	peptide deformylase activity
GOC52_RS18230	COG0758	DNA mediated transformation
GOC52_RS18235	COG2922	Belongs to the Smg family
GOC52_RS18245	COG1714	RDD family
GOC52_RS18250	COG1754	DNA topoisomerase type I activity
GOC52_RS18250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GOC52_RS18255	COG0009	L-threonylcarbamoyladenylate synthase
GOC52_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS18280	COG0616	signal peptide processing
GOC52_RS18285	COG0534	Mate efflux family protein
GOC52_RS18300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GOC52_RS18305	COG0625	glutathione transferase activity
GOC52_RS18315	COG1252	NADH dehydrogenase
GOC52_RS18330	COG2860	membrane
GOC52_RS18340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GOC52_RS18360	COG1846	Transcriptional regulator
GOC52_RS18390	COG0459	protein refolding
GOC52_RS18395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GOC52_RS18400	COG2356	endonuclease I
GOC52_RS18405	COG1324	tolerance protein
GOC52_RS18415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOC52_RS18425	COG0840	transmembrane signaling receptor activity
GOC52_RS18445	COG4585	Histidine kinase
GOC52_RS18465	COG0583	DNA-binding transcription factor activity
GOC52_RS18480	COG1785	Belongs to the alkaline phosphatase family
GOC52_RS18485	COG1686	Belongs to the peptidase S11 family
GOC52_RS18495	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOC52_RS18505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GOC52_RS18515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GOC52_RS18525	COG0511	ligase activity, forming carbon-carbon bonds
GOC52_RS18530	COG0439	Biotin carboxylase
GOC52_RS18545	COG2264	protein methyltransferase activity
GOC52_RS18555	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GOC52_RS18560	COG4589	Belongs to the CDS family
GOC52_RS18575	COG2453	phosphatase
GOC52_RS18575	COG0671	phosphoesterase, PA-phosphatase related
GOC52_RS18580	COG2267	carboxylic ester hydrolase activity
GOC52_RS18585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOC52_RS18590	COG0138	bifunctional purine biosynthesis protein purh
GOC52_RS18600	COG0151	Belongs to the GarS family
GOC52_RS18615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOC52_RS18620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GOC52_RS18625	COG2201	protein-glutamate methylesterase activity
GOC52_RS18630	COG2177	Part of the ABC transporter FtsEX involved in
GOC52_RS18635	COG2884	Cell division ATP-binding protein ftsE
GOC52_RS18645	COG3118	belongs to the thioredoxin family
GOC52_RS18650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GOC52_RS18655	COG3706	GGDEF domain
GOC52_RS18665	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GOC52_RS18700	COG1652	LysM domain
GOC52_RS18705	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GOC52_RS18705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GOC52_RS18710	COG1473	amidohydrolase
GOC52_RS18715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS18720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS18735	COG1289	transmembrane transporter activity
GOC52_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS18745	COG2814	Major facilitator Superfamily
GOC52_RS18775	COG0316	Belongs to the HesB IscA family
GOC52_RS18800	COG5002	protein histidine kinase activity
GOC52_RS18800	COG0784	Response regulator, receiver
GOC52_RS18800	COG2205	protein histidine kinase activity
GOC52_RS18820	COG1051	belongs to the nudix hydrolase family
GOC52_RS18835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GOC52_RS18840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GOC52_RS18845	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GOC52_RS18855	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GOC52_RS18860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOC52_RS18865	COG0730	response to heat
GOC52_RS18875	COG0134	indole-3-glycerol-phosphate synthase activity
GOC52_RS18880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GOC52_RS18910	COG1597	lipid kinase activity
GOC52_RS18925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GOC52_RS18930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GOC52_RS18940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GOC52_RS18940	COG2111	Na H antiporter
GOC52_RS18945	COG1006	Multisubunit Na H antiporter MnhC subunit
GOC52_RS18950	COG0651	ATP synthesis coupled electron transport
GOC52_RS18955	COG1863	multisubunit Na H antiporter MnhE subunit
GOC52_RS18960	COG2212	antiporter activity
GOC52_RS18965	COG1320	monovalent cation:proton antiporter activity
GOC52_RS18970	COG0530	calcium, potassium:sodium antiporter activity
GOC52_RS18985	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GOC52_RS19000	COG4804	nuclease activity
GOC52_RS19015	COG3104	oligopeptide transport
GOC52_RS19020	COG3483	tryptophan 2,3-dioxygenase activity
GOC52_RS19055	COG2378	regulation of single-species biofilm formation
GOC52_RS19070	COG2354	Protein conserved in bacteria
GOC52_RS19075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GOC52_RS19080	COG1368	sulfuric ester hydrolase activity
GOC52_RS19090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GOC52_RS19090	COG3264	Mechanosensitive ion channel
GOC52_RS19105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GOC52_RS19140	COG1166	arginine decarboxylase activity
GOC52_RS19145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GOC52_RS19165	COG2960	long-chain fatty acid transporting porin activity
GOC52_RS19200	COG0606	chelatase, subunit chli
GOC52_RS19220	COG0561	phosphatase activity
GOC52_RS19225	COG3932	Exopolysaccharide synthesis, ExoD
GOC52_RS19250	COG1999	signal sequence binding
GOC52_RS19255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GOC52_RS19260	COG1845	cytochrome c oxidase, subunit III
GOC52_RS19270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GOC52_RS19275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOC52_RS19290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOC52_RS19320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GOC52_RS19345	COG2031	fatty acid transporter
GOC52_RS19350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GOC52_RS19355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GOC52_RS19360	COG0489	protein tyrosine kinase activity
GOC52_RS19360	COG3206	protein involved in exopolysaccharide biosynthesis
GOC52_RS19380	COG1215	transferase activity, transferring glycosyl groups
GOC52_RS19390	COG1216	Glycosyl transferase, family 2
GOC52_RS19395	COG1045	serine acetyltransferase
GOC52_RS19420	COG0673	inositol 2-dehydrogenase activity
GOC52_RS19430	COG1501	Belongs to the glycosyl hydrolase 31 family
GOC52_RS19435	COG2222	sugar isomerase
GOC52_RS19440	COG1940	carbohydrate kinase activity
GOC52_RS19450	COG1349	DNA-binding transcription factor activity
GOC52_RS19455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GOC52_RS19460	COG2814	Major facilitator Superfamily
GOC52_RS19485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GOC52_RS19490	COG0156	8-amino-7-oxononanoate synthase activity
GOC52_RS19495	COG2267	carboxylic ester hydrolase activity
GOC52_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS19515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GOC52_RS19535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOC52_RS19540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOC52_RS19545	COG2205	protein histidine kinase activity
GOC52_RS19550	COG0745	RESPONSE REGULATOR receiver
GOC52_RS19555	COG3541	Predicted nucleotidyltransferase
GOC52_RS19560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GOC52_RS19585	COG0714	Associated with various cellular activities
GOC52_RS19600	COG0754	glutathionylspermidine amidase activity
GOC52_RS19610	COG0129	dihydroxy-acid dehydratase activity
GOC52_RS19620	COG1199	ATP-dependent helicase activity
GOC52_RS19630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GOC52_RS19650	COG3781	membrane
GOC52_RS19670	COG3291	Pkd domain containing protein
GOC52_RS19690	COG0625	glutathione transferase activity
GOC52_RS19710	COG2207	Transcriptional regulator
GOC52_RS19725	COG4555	ABC transporter
GOC52_RS19755	COG0543	2 iron, 2 sulfur cluster binding
GOC52_RS19755	COG0633	Ferredoxin
GOC52_RS19760	COG1131	(ABC) transporter
GOC52_RS19765	COG0842	Transport permease protein
GOC52_RS19775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GOC52_RS19785	COG0084	hydrolase, TatD family'
GOC52_RS19790	COG1643	Atp-dependent helicase
GOC52_RS19800	COG1187	pseudouridine synthase activity
GOC52_RS19815	COG0667	Aldo Keto reductase
GOC52_RS19830	COG1690	Belongs to the RtcB family
GOC52_RS19840	COG1959	2 iron, 2 sulfur cluster binding
GOC52_RS19845	COG0840	transmembrane signaling receptor activity
GOC52_RS19850	COG0583	DNA-binding transcription factor activity
GOC52_RS19855	COG2814	Major facilitator Superfamily
GOC52_RS19865	COG2267	carboxylic ester hydrolase activity
GOC52_RS19870	COG0393	Putative heavy-metal-binding
GOC52_RS19875	COG1042	CoA-binding domain protein
GOC52_RS19875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOC52_RS19875	COG0045	succinate-CoA ligase (ADP-forming) activity
GOC52_RS19880	COG2239	Acts as a magnesium transporter
GOC52_RS19895	COG3100	YcgL domain-containing protein
GOC52_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
GOC52_RS19930	COG0644	oxidoreductase
GOC52_RS19950	COG2986	histidine ammonia-lyase
GOC52_RS19960	COG0463	Glycosyl transferase, family 2
GOC52_RS19975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOC52_RS19980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOC52_RS19995	COG1294	oxidase, subunit
GOC52_RS20000	COG1271	oxidase subunit
GOC52_RS20035	COG1595	DNA-templated transcription, initiation
GOC52_RS20050	COG0494	nUDIX hydrolase
GOC52_RS20070	COG0408	coproporphyrinogen oxidase activity
GOC52_RS20080	COG2323	membrane
GOC52_RS20095	COG0589	response to stress
GOC52_RS20110	COG0210	DNA helicase
GOC52_RS20120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOC52_RS20125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GOC52_RS20130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GOC52_RS20135	COG1819	glycosyl
GOC52_RS20150	COG0251	oxidation-reduction process
GOC52_RS20185	COG0463	Glycosyl transferase, family 2
GOC52_RS20200	COG1475	DNA binding
GOC52_RS20205	COG1192	Involved in chromosome partitioning
GOC52_RS20210	COG0357	Ribosomal RNA small subunit methyltransferase G
GOC52_RS20215	COG2091	lysine biosynthetic process via aminoadipic acid
GOC52_RS20255	COG1971	Probably functions as a manganese efflux pump
GOC52_RS20260	COG0784	Response regulator, receiver
GOC52_RS20260	COG2205	protein histidine kinase activity
GOC52_RS20270	COG2911	Protein conserved in bacteria
GOC52_RS20275	COG0729	surface antigen
GOC52_RS20285	COG0752	glycyl-tRNA synthetase alpha subunit
GOC52_RS20290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GOC52_RS20295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOC52_RS20295	COG0519	Catalyzes the synthesis of GMP from XMP
GOC52_RS20305	COG0805	protein transport
GOC52_RS20315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GOC52_RS20325	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GOC52_RS20330	COG0596	Alpha beta hydrolase
GOC52_RS20330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GOC52_RS20335	COG0840	transmembrane signaling receptor activity
GOC52_RS20395	COG3135	benzoate transporter
GOC52_RS20410	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GOC52_RS20415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GOC52_RS20420	COG3706	GGDEF domain
GOC52_RS20450	COG0302	gtp cyclohydrolase
GOC52_RS20475	COG1289	transmembrane transporter activity
GOC52_RS20490	COG1074	ATP-dependent DNA helicase activity
GOC52_RS20495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GOC52_RS20500	COG1127	ABC transporter
GOC52_RS20505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GOC52_RS20510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GOC52_RS20525	COG2853	Lipoprotein
GOC52_RS20530	COG0386	Belongs to the glutathione peroxidase family
GOC52_RS20540	COG1322	Protein conserved in bacteria
GOC52_RS20555	COG0583	DNA-binding transcription factor activity
GOC52_RS20575	COG0667	Aldo Keto reductase
GOC52_RS20580	COG0531	amino acid
GOC52_RS20590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GOC52_RS20595	COG0861	Integral membrane protein TerC family
GOC52_RS20605	COG0584	glycerophosphoryl diester phosphodiesterase
GOC52_RS20625	COG0706	membrane insertase activity
GOC52_RS20630	COG0594	ribonuclease P activity
GOC52_RS20635	COG0230	Belongs to the bacterial ribosomal protein bL34 family