locus-tag	class	description
CCR98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCR98_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCR98_RS00020	COG0187	DNA topoisomerase II activity
CCR98_RS00025	COG1266	CAAX protease self-immunity
CCR98_RS00030	COG0501	Belongs to the peptidase M48B family
CCR98_RS00060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCR98_RS00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCR98_RS00095	COG4772	TonB-dependent receptor
CCR98_RS00130	COG0800	Aldolase
CCR98_RS00145	COG3186	Phenylalanine-4-hydroxylase
CCR98_RS00150	COG1522	sequence-specific DNA binding
CCR98_RS00155	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCR98_RS00170	COG4771	TonB-dependent receptor
CCR98_RS00175	COG0671	phosphoesterase, PA-phosphatase related
CCR98_RS00190	COG1119	ATPase activity
CCR98_RS00210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCR98_RS00215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CCR98_RS00240	COG3132	Protein of unknown function, DUF480
CCR98_RS00245	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CCR98_RS00250	COG0284	orotidine-5'-phosphate decarboxylase activity
CCR98_RS00255	COG5640	endopeptidase activity
CCR98_RS00265	COG2937	Belongs to the GPAT DAPAT family
CCR98_RS00275	COG0037	tRNA processing
CCR98_RS00280	COG2974	May be involved in recombination
CCR98_RS00290	COG1803	Methylglyoxal synthase
CCR98_RS00295	COG2205	protein histidine kinase activity
CCR98_RS00295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCR98_RS00300	COG0493	'glutamate synthase
CCR98_RS00305	COG0070	glutamate synthase
CCR98_RS00305	COG0069	glutamate synthase activity
CCR98_RS00305	COG0067	glutamate synthase
CCR98_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS00370	COG1205	dead DEAH box helicase
CCR98_RS00370	COG1111	helicase
CCR98_RS00405	COG0714	Associated with various cellular activities
CCR98_RS00425	COG0312	modulator of DNA gyrase
CCR98_RS00435	COG3550	peptidyl-serine autophosphorylation
CCR98_RS00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCR98_RS00475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCR98_RS00500	COG1881	PFAM PEBP family protein
CCR98_RS00515	COG1968	undecaprenyl-diphosphatase activity
CCR98_RS00520	COG0174	glutamine synthetase
CCR98_RS00525	COG0347	Belongs to the P(II) protein family
CCR98_RS00530	COG0004	ammonium transporteR
CCR98_RS00540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CCR98_RS00590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCR98_RS00615	COG3453	Protein conserved in bacteria
CCR98_RS00615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCR98_RS00635	COG0640	Transcriptional regulator
CCR98_RS00660	COG3852	Histidine kinase
CCR98_RS00665	COG2204	response regulator
CCR98_RS00670	COG2032	superoxide dismutase activity
CCR98_RS00675	COG2032	superoxide dismutase activity
CCR98_RS00685	COG0183	Belongs to the thiolase family
CCR98_RS00720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CCR98_RS00725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCR98_RS00775	COG3550	peptidyl-serine autophosphorylation
CCR98_RS00815	COG2837	iron assimilation
CCR98_RS00855	COG2197	response regulator
CCR98_RS00860	COG2205	protein histidine kinase activity
CCR98_RS00860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCR98_RS00865	COG3474	cytochrome
CCR98_RS00875	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS00880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CCR98_RS00890	COG0612	Peptidase, M16
CCR98_RS00900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCR98_RS00905	COG0596	Alpha beta hydrolase
CCR98_RS00915	COG0318	PFAM AMP-dependent synthetase and ligase
CCR98_RS00920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCR98_RS00930	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCR98_RS00940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCR98_RS00970	COG0339	signal peptide processing
CCR98_RS00985	COG0681	Belongs to the peptidase S26 family
CCR98_RS00990	COG2814	Major facilitator Superfamily
CCR98_RS00995	COG0583	DNA-binding transcription factor activity
CCR98_RS01000	COG0583	DNA-binding transcription factor activity
CCR98_RS01005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCR98_RS01010	COG2224	Isocitrate lyase
CCR98_RS01015	COG3706	GGDEF domain
CCR98_RS01040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCR98_RS01045	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS01065	COG0697	spore germination
CCR98_RS01075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCR98_RS01095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCR98_RS01100	COG1280	lysine exporter protein (LysE YggA)
CCR98_RS01105	COG1607	acyl-coa hydrolase
CCR98_RS01115	COG1902	pentaerythritol trinitrate reductase activity
CCR98_RS01140	COG1335	isochorismatase
CCR98_RS01145	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCR98_RS01155	COG1056	cytidyltransferase-related domain
CCR98_RS01155	COG1051	belongs to the nudix hydrolase family
CCR98_RS01160	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCR98_RS01165	COG1396	sequence-specific DNA binding
CCR98_RS01165	COG3800	Transcriptional regulator
CCR98_RS01175	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS01180	COG1024	Enoyl-CoA hydratase
CCR98_RS01185	COG1024	Enoyl-CoA hydratase
CCR98_RS01195	COG1764	response to oxidative stress
CCR98_RS01295	COG0659	secondary active sulfate transmembrane transporter activity
CCR98_RS01315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCR98_RS01335	COG3228	Belongs to the MtfA family
CCR98_RS01345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCR98_RS01345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCR98_RS01350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CCR98_RS01405	COG3237	CsbD-like
CCR98_RS01415	COG0180	Tryptophanyl-tRNA synthetase
CCR98_RS01440	COG0477	Major facilitator Superfamily
CCR98_RS01445	COG0697	spore germination
CCR98_RS01465	COG0577	efflux transmembrane transporter activity
CCR98_RS01465	COG1136	(ABC) transporter
CCR98_RS01475	COG1136	(ABC) transporter
CCR98_RS01480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS01495	COG4585	Histidine kinase
CCR98_RS01500	COG2197	response regulator
CCR98_RS01515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCR98_RS01525	COG0628	permease
CCR98_RS01545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCR98_RS01560	COG5507	3-demethylubiquinone-9 3-methyltransferase
CCR98_RS01590	COG2814	Major facilitator Superfamily
CCR98_RS01595	COG0583	DNA-binding transcription factor activity
CCR98_RS01600	COG4807	Protein conserved in bacteria
CCR98_RS01605	COG4221	oxidoreductase activity
CCR98_RS01615	COG0018	arginyl-trna synthetase
CCR98_RS01620	COG2003	Belongs to the UPF0758 family
CCR98_RS01625	COG2197	response regulator
CCR98_RS01630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCR98_RS01635	COG0756	dUTP diphosphatase activity
CCR98_RS01650	COG2205	protein histidine kinase activity
CCR98_RS01660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CCR98_RS01665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CCR98_RS01680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCR98_RS01685	COG0708	Exodeoxyribonuclease III
CCR98_RS01690	COG2211	Major facilitator Superfamily
CCR98_RS01700	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCR98_RS01705	COG0739	heme binding
CCR98_RS01710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCR98_RS01770	COG2234	aminopeptidase activity
CCR98_RS01780	COG4942	peptidase
CCR98_RS01785	COG0793	Belongs to the peptidase S41A family
CCR98_RS01795	COG2067	long-chain fatty acid transport protein
CCR98_RS01820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCR98_RS01865	COG0109	protoheme IX farnesyltransferase activity
CCR98_RS01885	COG0358	DNA primase activity
CCR98_RS01890	COG1295	ribonuclease BN
CCR98_RS01905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCR98_RS01915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCR98_RS01920	COG0668	transmembrane transport
CCR98_RS01935	COG2133	pyrroloquinoline quinone binding
CCR98_RS01940	COG4682	membrane
CCR98_RS01950	COG0531	amino acid
CCR98_RS01960	COG1737	Transcriptional regulator
CCR98_RS01965	COG4948	Mandelate Racemase Muconate Lactonizing
CCR98_RS02015	COG5383	Protein conserved in bacteria
CCR98_RS02025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCR98_RS02030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CCR98_RS02060	COG0778	Nitroreductase
CCR98_RS02065	COG2353	YceI-like domain
CCR98_RS02075	COG2375	cellular response to nickel ion
CCR98_RS02110	COG4735	regulation of single-species biofilm formation
CCR98_RS02135	COG1104	cysteine desulfurase activity
CCR98_RS02140	COG1104	cysteine desulfurase activity
CCR98_RS02190	COG2801	Transposase and inactivated derivatives
CCR98_RS02265	COG2267	carboxylic ester hydrolase activity
CCR98_RS02285	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CCR98_RS02335	COG0488	(ABC) transporter
CCR98_RS02340	COG0583	DNA-binding transcription factor activity
CCR98_RS02350	COG2814	Major facilitator Superfamily
CCR98_RS02355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CCR98_RS02360	COG1113	amino acid transport
CCR98_RS02365	COG0741	lytic transglycosylase activity
CCR98_RS02390	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CCR98_RS02400	COG5507	3-demethylubiquinone-9 3-methyltransferase
CCR98_RS02405	COG4941	Belongs to the sigma-70 factor family
CCR98_RS02435	COG3275	phosphorelay sensor kinase activity
CCR98_RS02440	COG3279	Response regulator of the LytR AlgR family
CCR98_RS02460	COG1309	transcriptional regulator
CCR98_RS02470	COG2814	Major facilitator Superfamily
CCR98_RS02475	COG3590	peptidase
CCR98_RS02480	COG5001	Diguanylate cyclase
CCR98_RS02485	COG0583	DNA-binding transcription factor activity
CCR98_RS02495	COG3384	dioxygenase
CCR98_RS02500	COG0025	NhaP-type Na H and K H
CCR98_RS02525	COG1360	Flagellar Motor Protein
CCR98_RS02555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCR98_RS02570	COG5002	protein histidine kinase activity
CCR98_RS02585	COG2813	Specifically methylates the guanine in position
CCR98_RS02590	COG1187	pseudouridine synthase activity
CCR98_RS02595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCR98_RS02605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCR98_RS02610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCR98_RS02620	COG2910	NAD(P)H-binding
CCR98_RS02625	COG0583	DNA-binding transcription factor activity
CCR98_RS02630	COG2226	methyltransferase
CCR98_RS02655	COG1956	GAF domain-containing protein
CCR98_RS02660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCR98_RS02665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCR98_RS02670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCR98_RS02675	COG0785	Cytochrome C biogenesis protein
CCR98_RS02675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCR98_RS02680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCR98_RS02685	COG0745	RESPONSE REGULATOR receiver
CCR98_RS02690	COG5002	protein histidine kinase activity
CCR98_RS02695	COG2205	protein histidine kinase activity
CCR98_RS02700	COG0745	RESPONSE REGULATOR receiver
CCR98_RS02705	COG0367	asparagine synthase
CCR98_RS02715	COG0720	synthase
CCR98_RS02730	COG0513	Belongs to the DEAD box helicase family
CCR98_RS02740	COG0625	glutathione transferase activity
CCR98_RS02780	COG0626	cystathionine gamma-synthase activity
CCR98_RS02810	COG0438	transferase activity, transferring glycosyl groups
CCR98_RS02820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCR98_RS02830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCR98_RS02845	COG0463	Glycosyl transferase, family 2
CCR98_RS02885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCR98_RS02915	COG1127	ABC transporter
CCR98_RS02920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCR98_RS02935	COG0442	prolyl-tRNA aminoacylation
CCR98_RS02945	COG1183	phosphatidylcholine synthase activity
CCR98_RS02955	COG0456	acetyltransferase
CCR98_RS02965	COG0525	valine-tRNA ligase activity
CCR98_RS02980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCR98_RS02990	COG0795	lipopolysaccharide-transporting ATPase activity
CCR98_RS03000	COG4974	Belongs to the 'phage' integrase family
CCR98_RS03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCR98_RS03025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCR98_RS03025	COG0047	phosphoribosylformylglycinamidine synthase activity
CCR98_RS03030	COG5295	Hep Hag repeat protein
CCR98_RS03035	COG1404	Belongs to the peptidase S8 family
CCR98_RS03040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCR98_RS03045	COG1459	type II secretion system
CCR98_RS03050	COG2165	general secretion pathway protein
CCR98_RS03055	COG4970	Tfp pilus assembly protein FimT
CCR98_RS03060	COG2165	general secretion pathway protein
CCR98_RS03065	COG4795	General secretion pathway protein
CCR98_RS03070	COG3156	type II secretion system protein K
CCR98_RS03075	COG3166	PFAM Fimbrial assembly family protein
CCR98_RS03090	COG1450	Type ii and iii secretion system protein
CCR98_RS03100	COG0463	Glycosyl transferase, family 2
CCR98_RS03115	COG3539	Fimbrial protein
CCR98_RS03135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCR98_RS03145	COG1215	transferase activity, transferring glycosyl groups
CCR98_RS03160	COG2252	PERMEase
CCR98_RS03165	COG0488	(ABC) transporter
CCR98_RS03175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCR98_RS03195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCR98_RS03200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCR98_RS03200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCR98_RS03230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCR98_RS03235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCR98_RS03270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CCR98_RS03270	COG2755	lipolytic protein G-D-S-L family
CCR98_RS03275	COG0277	FAD linked oxidase domain protein
CCR98_RS03280	COG1988	membrane-bound metal-dependent
CCR98_RS03315	COG2001	Belongs to the MraZ family
CCR98_RS03320	COG0275	rRNA processing
CCR98_RS03325	COG3116	cell division
CCR98_RS03340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCR98_RS03360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCR98_RS03365	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCR98_RS03370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCR98_RS03380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCR98_RS03385	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CCR98_RS03395	COG0739	heme binding
CCR98_RS03400	COG0653	protein targeting
CCR98_RS03405	COG0494	nUDIX hydrolase
CCR98_RS03415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCR98_RS03425	COG3275	phosphorelay sensor kinase activity
CCR98_RS03435	COG0402	S-adenosylhomocysteine deaminase activity
CCR98_RS03455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCR98_RS03460	COG3409	Peptidoglycan-binding domain 1 protein
CCR98_RS03460	COG3773	Cell wall hydrolase
CCR98_RS03470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCR98_RS03480	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCR98_RS03485	COG1607	acyl-coa hydrolase
CCR98_RS03490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCR98_RS03510	COG4106	trans-aconitate 2-methyltransferase activity
CCR98_RS03515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCR98_RS03530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCR98_RS03535	COG0667	Aldo Keto reductase
CCR98_RS03545	COG4771	TonB-dependent receptor
CCR98_RS03570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCR98_RS03575	COG4181	ATPase activity
CCR98_RS03590	COG0642	Histidine kinase
CCR98_RS03600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCR98_RS03605	COG0861	Integral membrane protein TerC family
CCR98_RS03610	COG2814	Major facilitator Superfamily
CCR98_RS03615	COG1704	LemA family
CCR98_RS03630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCR98_RS03635	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCR98_RS03650	COG3738	Protein conserved in bacteria
CCR98_RS03655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCR98_RS03660	COG2967	ApaG domain
CCR98_RS03665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCR98_RS03670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCR98_RS03675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCR98_RS03680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CCR98_RS03690	COG2096	Adenosyltransferase
CCR98_RS03700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCR98_RS03705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCR98_RS03710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCR98_RS03715	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CCR98_RS03735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCR98_RS03745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCR98_RS03755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCR98_RS03760	COG0583	DNA-binding transcription factor activity
CCR98_RS03765	COG3634	alkyl hydroperoxide reductase activity
CCR98_RS03825	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CCR98_RS03850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CCR98_RS03865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCR98_RS03870	COG1404	Belongs to the peptidase S8 family
CCR98_RS03890	COG1295	ribonuclease BN
CCR98_RS03895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCR98_RS03915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCR98_RS03920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCR98_RS03935	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCR98_RS03945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCR98_RS03950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CCR98_RS03955	COG0193	aminoacyl-tRNA hydrolase activity
CCR98_RS03960	COG0012	GTP binding
CCR98_RS03970	COG2197	response regulator
CCR98_RS03975	COG0784	Response regulator, receiver
CCR98_RS03975	COG2205	protein histidine kinase activity
CCR98_RS03980	COG2203	Gaf domain
CCR98_RS03980	COG2200	EAL domain
CCR98_RS03980	COG2199	diguanylate cyclase activity
CCR98_RS03985	COG2205	protein histidine kinase activity
CCR98_RS03985	COG0784	Response regulator, receiver
CCR98_RS03990	COG4206	TonB-dependent receptor
CCR98_RS03995	COG4242	Belongs to the peptidase S51 family
CCR98_RS04020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCR98_RS04035	COG0250	Participates in transcription elongation, termination and antitermination
CCR98_RS04040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCR98_RS04045	COG0081	regulation of translation
CCR98_RS04050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCR98_RS04055	COG0222	ribosome binding
CCR98_RS04060	COG0085	RNA polymerase activity
CCR98_RS04065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCR98_RS04070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCR98_RS04075	COG0049	tRNA binding
CCR98_RS04080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCR98_RS04085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCR98_RS04090	COG0051	transcription antitermination factor activity, RNA binding
CCR98_RS04095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCR98_RS04100	COG0088	Forms part of the polypeptide exit tunnel
CCR98_RS04105	COG0089	rRNA binding
CCR98_RS04110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCR98_RS04115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCR98_RS04120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCR98_RS04125	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCR98_RS04130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCR98_RS04135	COG0255	Belongs to the universal ribosomal protein uL29 family
CCR98_RS04140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCR98_RS04145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCR98_RS04150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCR98_RS04155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCR98_RS04160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCR98_RS04170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCR98_RS04175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCR98_RS04180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCR98_RS04185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCR98_RS04190	COG1841	ribosomal large subunit assembly
CCR98_RS04195	COG0200	Binds to the 23S rRNA
CCR98_RS04200	COG0201	protein transport
CCR98_RS04205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCR98_RS04210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCR98_RS04215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCR98_RS04220	COG0202	RNA polymerase activity
CCR98_RS04225	COG0203	ribosomal protein L17
CCR98_RS04240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CCR98_RS04250	COG0154	amidase activity
CCR98_RS04265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCR98_RS04270	COG0039	L-malate dehydrogenase activity
CCR98_RS04275	COG0564	pseudouridine synthase activity
CCR98_RS04280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCR98_RS04295	COG0625	glutathione transferase activity
CCR98_RS04305	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCR98_RS04305	COG1902	pentaerythritol trinitrate reductase activity
CCR98_RS04310	COG2364	Membrane
CCR98_RS04315	COG0604	alcohol dehydrogenase
CCR98_RS04330	COG1187	pseudouridine synthase activity
CCR98_RS04350	COG1063	alcohol dehydrogenase
CCR98_RS04360	COG0588	phosphoglycerate mutase activity
CCR98_RS04365	COG0285	dihydrofolate synthase activity
CCR98_RS04385	COG2833	Protein of unknown function (DUF455)
CCR98_RS04395	COG3291	Pkd domain containing protein
CCR98_RS04400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCR98_RS04405	COG0671	phosphoesterase, PA-phosphatase related
CCR98_RS04410	COG0438	transferase activity, transferring glycosyl groups
CCR98_RS04415	COG4206	TonB-dependent receptor
CCR98_RS04420	COG0248	Ppx GppA phosphatase
CCR98_RS04425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CCR98_RS04440	COG4783	chaperone-mediated protein folding
CCR98_RS04455	COG0473	3-isopropylmalate dehydrogenase activity
CCR98_RS04520	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCR98_RS04525	COG0740	serine-type endopeptidase activity
CCR98_RS04530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCR98_RS04570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCR98_RS04580	COG1388	LysM domain
CCR98_RS04580	COG3942	CHAP domain
CCR98_RS04585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCR98_RS04590	COG2226	methyltransferase
CCR98_RS04595	COG0328	RNA-DNA hybrid ribonuclease activity
CCR98_RS04600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCR98_RS04605	COG0631	protein serine/threonine phosphatase activity
CCR98_RS04620	COG0859	PFAM glycosyl transferase family 9
CCR98_RS04625	COG3642	lipopolysaccharide core region biosynthetic process
CCR98_RS04630	COG1234	tRNA 3'-trailer cleavage
CCR98_RS04645	COG2076	Multidrug Resistance protein
CCR98_RS04725	COG3047	cAMP biosynthetic process
CCR98_RS04725	COG2885	chlorophyll binding
CCR98_RS04740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCR98_RS04745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCR98_RS04755	COG0537	adenosine 5'-monophosphoramidase activity
CCR98_RS04775	COG0714	Associated with various cellular activities
CCR98_RS04790	COG1399	metal-binding, possibly nucleic acid-binding protein
CCR98_RS04795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCR98_RS04800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCR98_RS04810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCR98_RS04825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCR98_RS04830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCR98_RS04835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCR98_RS04840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCR98_RS04925	COG4774	siderophore transport
CCR98_RS04940	COG2223	nitrite transmembrane transporter activity
CCR98_RS04955	COG2226	methyltransferase
CCR98_RS04960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCR98_RS04965	COG0697	spore germination
CCR98_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS04975	COG0583	DNA-binding transcription factor activity
CCR98_RS05010	COG0583	DNA-binding transcription factor activity
CCR98_RS05020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCR98_RS05035	COG0667	Aldo Keto reductase
CCR98_RS05050	COG0456	acetyltransferase
CCR98_RS05060	COG0519	Catalyzes the synthesis of GMP from XMP
CCR98_RS05065	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CCR98_RS05070	COG1678	Uncharacterized ACR, COG1678
CCR98_RS05075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCR98_RS05080	COG0540	Belongs to the ATCase OTCase family
CCR98_RS05100	COG2239	Acts as a magnesium transporter
CCR98_RS05105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCR98_RS05120	COG1660	Displays ATPase and GTPase activities
CCR98_RS05125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCR98_RS05130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCR98_RS05135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCR98_RS05145	COG1137	ATPase activity
CCR98_RS05160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCR98_RS05175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCR98_RS05195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCR98_RS05215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCR98_RS05225	COG0628	permease
CCR98_RS05235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCR98_RS05245	COG2261	transglycosylase associated protein
CCR98_RS05255	COG1555	photosystem II stabilization
CCR98_RS05275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCR98_RS05280	COG1477	protein flavinylation
CCR98_RS05305	COG4771	TonB-dependent receptor
CCR98_RS05315	COG3128	pkhd-type hydroxylase
CCR98_RS05325	COG4774	siderophore transport
CCR98_RS05335	COG2146	nitrite reductase [NAD(P)H] activity
CCR98_RS05350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCR98_RS05355	COG0719	Fe-S assembly protein
CCR98_RS05360	COG0396	ATPase activity
CCR98_RS05365	COG0719	Fe-S assembly protein
CCR98_RS05370	COG1959	2 iron, 2 sulfur cluster binding
CCR98_RS05380	COG0693	protein deglycase activity
CCR98_RS05405	COG1764	response to oxidative stress
CCR98_RS05410	COG0384	phenazine biosynthesis protein PhzF
CCR98_RS05415	COG0384	phenazine biosynthesis protein PhzF
CCR98_RS05420	COG0527	aspartate kinase activity
CCR98_RS05430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCR98_RS05450	COG0142	geranyltranstransferase activity
CCR98_RS05455	COG0366	Alpha amylase catalytic
CCR98_RS05465	COG1082	Xylose isomerase domain protein TIM barrel
CCR98_RS05475	COG2190	(PTS) system
CCR98_RS05475	COG2211	Major facilitator Superfamily
CCR98_RS05505	COG1131	(ABC) transporter
CCR98_RS05510	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CCR98_RS05525	COG0629	single-stranded DNA binding
CCR98_RS05550	COG2010	Cytochrome c
CCR98_RS05560	COG0673	inositol 2-dehydrogenase activity
CCR98_RS05565	COG2211	Major facilitator Superfamily
CCR98_RS05575	COG1609	Transcriptional regulator
CCR98_RS05625	COG3655	Transcriptional regulator
CCR98_RS05630	COG1253	flavin adenine dinucleotide binding
CCR98_RS05635	COG1408	metallophosphoesterase
CCR98_RS05645	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CCR98_RS05665	COG2259	Doxx family
CCR98_RS05695	COG0477	Major facilitator Superfamily
CCR98_RS05710	COG1802	Transcriptional regulator
CCR98_RS05745	COG3052	prosthetic group binding
CCR98_RS05760	COG0579	oxidoreductase
CCR98_RS05790	COG3104	oligopeptide transport
CCR98_RS05800	COG1297	OPT oligopeptide transporter protein
CCR98_RS05805	COG1506	peptidase
CCR98_RS05805	COG0823	Involved in the tonB-independent uptake of proteins
CCR98_RS05820	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CCR98_RS05825	COG2894	cell division
CCR98_RS05830	COG0850	regulation of cytokinetic process
CCR98_RS05840	COG4585	Histidine kinase
CCR98_RS05845	COG2197	response regulator
CCR98_RS05885	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CCR98_RS05895	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CCR98_RS05905	COG1595	DNA-templated transcription, initiation
CCR98_RS05915	COG1946	Acyl-CoA thioesterase
CCR98_RS05935	COG0824	Thioesterase
CCR98_RS05940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCR98_RS05945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCR98_RS05950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCR98_RS05955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCR98_RS05960	COG0268	Binds directly to 16S ribosomal RNA
CCR98_RS05965	COG0728	peptidoglycan biosynthetic process
CCR98_RS05970	COG0196	riboflavin kinase activity
CCR98_RS05975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCR98_RS05985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCR98_RS06010	COG4206	TonB-dependent receptor
CCR98_RS06030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCR98_RS06055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCR98_RS06060	COG1845	cytochrome c oxidase, subunit III
CCR98_RS06065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCR98_RS06080	COG0326	Molecular chaperone. Has ATPase activity
CCR98_RS06100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCR98_RS06120	COG0228	four-way junction DNA binding
CCR98_RS06125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCR98_RS06130	COG0336	Belongs to the RNA methyltransferase TrmD family
CCR98_RS06135	COG0335	large ribosomal subunit rRNA binding
CCR98_RS06155	COG0534	Mate efflux family protein
CCR98_RS06175	COG0753	catalase activity
CCR98_RS06190	COG2831	hemolysin activation secretion protein
CCR98_RS06195	COG3210	domain, Protein
CCR98_RS06205	COG3210	domain, Protein
CCR98_RS06240	COG0840	transmembrane signaling receptor activity
CCR98_RS06245	COG3134	Outer membrane lipoprotein
CCR98_RS06260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS06280	COG0024	Methionine aminopeptidase
CCR98_RS06305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCR98_RS06330	COG1647	Serine aminopeptidase, S33
CCR98_RS06335	COG0642	Histidine kinase
CCR98_RS06355	COG2814	Major facilitator Superfamily
CCR98_RS06360	COG3706	GGDEF domain
CCR98_RS06380	COG0588	phosphoglycerate mutase activity
CCR98_RS06390	COG3590	peptidase
CCR98_RS06400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCR98_RS06410	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCR98_RS06415	COG0745	RESPONSE REGULATOR receiver
CCR98_RS06420	COG2205	protein histidine kinase activity
CCR98_RS06425	COG4452	Inner membrane protein CreD
CCR98_RS06440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCR98_RS06445	COG0735	belongs to the Fur family
CCR98_RS06485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCR98_RS06525	COG5001	Diguanylate cyclase
CCR98_RS06525	COG5002	protein histidine kinase activity
CCR98_RS06535	COG1187	pseudouridine synthase activity
CCR98_RS06545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCR98_RS06575	COG1132	(ABC) transporter
CCR98_RS06625	COG1695	Transcriptional regulator
CCR98_RS06645	COG1981	membrane
CCR98_RS06650	COG0825	malonyl-CoA metabolic process
CCR98_RS06665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCR98_RS06670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCR98_RS06675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCR98_RS06685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCR98_RS06690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCR98_RS06695	COG0750	zinc metalloprotease
CCR98_RS06700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCR98_RS06705	COG0575	Belongs to the CDS family
CCR98_RS06710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCR98_RS06715	COG0233	cytoplasmic translational termination
CCR98_RS06720	COG0528	UMP kinase activity
CCR98_RS06730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCR98_RS06735	COG0052	Belongs to the universal ribosomal protein uS2 family
CCR98_RS06755	COG3188	usher protein
CCR98_RS06775	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CCR98_RS06790	COG1393	Belongs to the ArsC family
CCR98_RS06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCR98_RS06805	COG0367	asparagine synthase
CCR98_RS06810	COG0475	glutathione-regulated potassium exporter activity
CCR98_RS06845	COG1566	PFAM secretion protein HlyD family protein
CCR98_RS06850	COG2814	Major facilitator Superfamily
CCR98_RS06860	COG0583	DNA-binding transcription factor activity
CCR98_RS06880	COG0557	exoribonuclease II activity
CCR98_RS06890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCR98_RS06895	COG1538	Outer membrane efflux protein
CCR98_RS06900	COG1136	(ABC) transporter
CCR98_RS06900	COG0577	efflux transmembrane transporter activity
CCR98_RS06905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS06925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCR98_RS06930	COG2259	Doxx family
CCR98_RS06940	COG3220	belongs to the UPF0276 family
CCR98_RS06950	COG0704	Plays a role in the regulation of phosphate uptake
CCR98_RS06960	COG0581	inorganic phosphate transmembrane transporter activity
CCR98_RS06965	COG0573	inorganic phosphate transmembrane transporter activity
CCR98_RS06970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCR98_RS06975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCR98_RS06985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCR98_RS06995	COG1024	Enoyl-CoA hydratase
CCR98_RS07005	COG0494	nUDIX hydrolase
CCR98_RS07025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCR98_RS07025	COG0116	Belongs to the methyltransferase superfamily
CCR98_RS07050	COG2733	membrane
CCR98_RS07060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCR98_RS07065	COG1012	belongs to the aldehyde dehydrogenase family
CCR98_RS07070	COG0477	Major facilitator Superfamily
CCR98_RS07075	COG2703	oxygen carrier activity
CCR98_RS07100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCR98_RS07110	COG0174	glutamine synthetase
CCR98_RS07120	COG3842	ATPase activity
CCR98_RS07125	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCR98_RS07130	COG1177	transmembrane transport
CCR98_RS07135	COG1012	belongs to the aldehyde dehydrogenase family
CCR98_RS07150	COG4535	Mg2 and Co2 transporter CorC
CCR98_RS07165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCR98_RS07170	COG1702	phosphate starvation-inducible protein PhoH
CCR98_RS07180	COG1131	(ABC) transporter
CCR98_RS07185	COG0842	Transport permease protein
CCR98_RS07190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCR98_RS07205	COG0741	lytic transglycosylase activity
CCR98_RS07210	COG0723	plastoquinol--plastocyanin reductase activity
CCR98_RS07215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CCR98_RS07220	COG2857	Cytochrome c1
CCR98_RS07225	COG0625	glutathione transferase activity
CCR98_RS07230	COG2969	positive regulation of protein catabolic process
CCR98_RS07265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCR98_RS07275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCR98_RS07290	COG1611	Belongs to the LOG family
CCR98_RS07335	COG0556	nucleotide-excision repair
CCR98_RS07360	COG3713	MltA-interacting MipA family protein
CCR98_RS07365	COG0745	RESPONSE REGULATOR receiver
CCR98_RS07375	COG0658	competence protein
CCR98_RS07375	COG2333	competence protein COMEC
CCR98_RS07380	COG0811	peptide transport
CCR98_RS07395	COG1663	tetraacyldisaccharide 4'-kinase activity
CCR98_RS07400	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CCR98_RS07405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCR98_RS07415	COG0322	excinuclease ABC activity
CCR98_RS07450	COG1136	(ABC) transporter
CCR98_RS07450	COG0577	efflux transmembrane transporter activity
CCR98_RS07500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCR98_RS07540	COG4977	sequence-specific DNA binding
CCR98_RS07540	COG1917	Cupin 2, conserved barrel domain protein
CCR98_RS07545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCR98_RS07565	COG0348	domain, Protein
CCR98_RS07580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCR98_RS07585	COG0582	viral genome integration into host DNA
CCR98_RS07625	COG0629	single-stranded DNA binding
CCR98_RS07710	COG0305	Participates in initiation and elongation during chromosome replication
CCR98_RS07905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CCR98_RS07910	COG0069	glutamate synthase activity
CCR98_RS07940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCR98_RS07955	COG1253	flavin adenine dinucleotide binding
CCR98_RS07975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCR98_RS07990	COG0504	CTP synthase activity
CCR98_RS07995	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCR98_RS08010	COG0148	phosphopyruvate hydratase activity
CCR98_RS08015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCR98_RS08020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCR98_RS08025	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCR98_RS08035	COG2840	Smr protein MutS2
CCR98_RS08040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CCR98_RS08045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCR98_RS08070	COG1534	Rna-binding protein
CCR98_RS08075	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CCR98_RS08080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCR98_RS08090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCR98_RS08095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCR98_RS08100	COG1923	regulation of RNA biosynthetic process
CCR98_RS08105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCR98_RS08110	COG1546	Belongs to the CinA family
CCR98_RS08115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCR98_RS08120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCR98_RS08125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCR98_RS08130	COG2137	regulation of response to DNA damage stimulus
CCR98_RS08135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCR98_RS08140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CCR98_RS08180	COG3540	Alkaline phosphatase
CCR98_RS08195	COG3258	Cytochrome c
CCR98_RS08210	COG2223	nitrite transmembrane transporter activity
CCR98_RS08215	COG1741	Belongs to the pirin family
CCR98_RS08220	COG0583	DNA-binding transcription factor activity
CCR98_RS08245	COG0352	thiamine-phosphate diphosphorylase activity
CCR98_RS08245	COG0351	phosphomethylpyrimidine kinase
CCR98_RS08260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CCR98_RS08265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCR98_RS08275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCR98_RS08285	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCR98_RS08290	COG0477	Major facilitator Superfamily
CCR98_RS08300	COG0617	tRNA 3'-terminal CCA addition
CCR98_RS08305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCR98_RS08310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCR98_RS08315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCR98_RS08325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCR98_RS08330	COG0166	Belongs to the GPI family
CCR98_RS08335	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CCR98_RS08345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCR98_RS08350	COG0671	phosphoesterase, PA-phosphatase related
CCR98_RS08360	COG0800	Aldolase
CCR98_RS08365	COG0129	dihydroxy-acid dehydratase activity
CCR98_RS08375	COG0837	glucose binding
CCR98_RS08380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CCR98_RS08390	COG0354	folic acid binding
CCR98_RS08400	COG2009	succinate dehydrogenase
CCR98_RS08405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CCR98_RS08410	COG1053	succinate dehydrogenase
CCR98_RS08430	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCR98_RS08445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CCR98_RS08455	COG0552	protein localization to endoplasmic reticulum
CCR98_RS08470	COG0742	ribosomal rna small subunit methyltransferase
CCR98_RS08475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCR98_RS08485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCR98_RS08490	COG0405	Gamma-glutamyltransferase
CCR98_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCR98_RS08515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCR98_RS08535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCR98_RS08540	COG0415	Belongs to the DNA photolyase family
CCR98_RS08545	COG2885	chlorophyll binding
CCR98_RS08550	COG0583	DNA-binding transcription factor activity
CCR98_RS08615	COG2124	cytochrome p450
CCR98_RS08660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCR98_RS08670	COG2914	Belongs to the UPF0125 (RnfH) family
CCR98_RS08675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCR98_RS08680	COG0735	belongs to the Fur family
CCR98_RS08690	COG0583	DNA-binding transcription factor activity
CCR98_RS08695	COG0497	DNA recombination
CCR98_RS08700	COG1420	regulation of RNA biosynthetic process
CCR98_RS08705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCR98_RS08710	COG0443	Heat shock 70 kDa protein
CCR98_RS08715	COG0484	heat shock protein binding
CCR98_RS08720	COG2207	Transcriptional regulator
CCR98_RS08725	COG2223	nitrite transmembrane transporter activity
CCR98_RS08735	COG0287	Prephenate dehydrogenase
CCR98_RS08735	COG1605	Chorismate mutase
CCR98_RS08745	COG1132	(ABC) transporter
CCR98_RS08765	COG5001	Diguanylate cyclase
CCR98_RS08775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCR98_RS08780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCR98_RS08785	COG0343	queuine tRNA-ribosyltransferase activity
CCR98_RS08790	COG1862	Preprotein translocase
CCR98_RS08800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCR98_RS08805	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCR98_RS08815	COG2081	HI0933 family
CCR98_RS08820	COG4681	YaeQ
CCR98_RS08825	COG0564	pseudouridine synthase activity
CCR98_RS08835	COG1278	Cold shock
CCR98_RS08840	COG0625	glutathione transferase activity
CCR98_RS08845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCR98_RS08855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCR98_RS08860	COG0513	Belongs to the DEAD box helicase family
CCR98_RS08870	COG0583	DNA-binding transcription factor activity
CCR98_RS08875	COG0488	(ABC) transporter
CCR98_RS08900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS08915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCR98_RS08920	COG2957	Belongs to the agmatine deiminase family
CCR98_RS08930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCR98_RS08935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCR98_RS08945	COG0776	regulation of translation
CCR98_RS08955	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CCR98_RS08970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCR98_RS08975	COG0183	Belongs to the thiolase family
CCR98_RS08980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCR98_RS08980	COG1024	Enoyl-CoA hydratase
CCR98_RS08990	COG0105	UTP biosynthetic process
CCR98_RS08995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCR98_RS09000	COG0457	Tetratricopeptide repeat
CCR98_RS09000	COG0859	PFAM glycosyl transferase family 9
CCR98_RS09005	COG1426	Protein conserved in bacteria
CCR98_RS09010	COG2976	Protein conserved in bacteria
CCR98_RS09015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCR98_RS09020	COG1160	GTP binding
CCR98_RS09040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CCR98_RS09045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCR98_RS09045	COG0475	glutathione-regulated potassium exporter activity
CCR98_RS09065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCR98_RS09065	COG0519	Catalyzes the synthesis of GMP from XMP
CCR98_RS09090	COG0583	DNA-binding transcription factor activity
CCR98_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS09140	COG0640	Transcriptional regulator
CCR98_RS09170	COG0431	NADPH-dependent FMN reductase
CCR98_RS09180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCR98_RS09185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCR98_RS09190	COG1473	amidohydrolase
CCR98_RS09200	COG1126	abc transporter atp-binding protein
CCR98_RS09205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCR98_RS09235	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CCR98_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS09250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCR98_RS09265	COG1309	transcriptional regulator
CCR98_RS09280	COG0697	spore germination
CCR98_RS09285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCR98_RS09290	COG0167	dihydroorotate dehydrogenase activity
CCR98_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
CCR98_RS09345	COG0784	Response regulator, receiver
CCR98_RS09345	COG4191	Histidine kinase
CCR98_RS09350	COG3850	Histidine kinase
CCR98_RS09350	COG3437	response regulator, receiver
CCR98_RS09350	COG2205	protein histidine kinase activity
CCR98_RS09350	COG4999	Histidine kinase
CCR98_RS09355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCR98_RS09365	COG0745	RESPONSE REGULATOR receiver
CCR98_RS09375	COG0640	Transcriptional regulator
CCR98_RS09410	COG0460	homoserine dehydrogenase
CCR98_RS09410	COG0527	aspartate kinase activity
CCR98_RS09420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCR98_RS09425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCR98_RS09430	COG0124	histidyl-tRNA synthetase
CCR98_RS09445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCR98_RS09450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCR98_RS09455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCR98_RS09460	COG0131	Imidazoleglycerol-phosphate dehydratase
CCR98_RS09460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCR98_RS09465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCR98_RS09470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCR98_RS09475	COG0107	imidazoleglycerol-phosphate synthase activity
CCR98_RS09480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCR98_RS09480	COG0140	phosphoribosyl-ATP diphosphatase activity
CCR98_RS09500	COG1446	asparaginase
CCR98_RS09505	COG3142	Participates in the control of copper homeostasis
CCR98_RS09520	COG0789	Transcriptional regulator
CCR98_RS09540	COG3537	Alpha-1,2-mannosidase
CCR98_RS09545	COG1609	Transcriptional regulator
CCR98_RS09555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCR98_RS09570	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CCR98_RS09575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CCR98_RS09580	COG0235	Class ii aldolase
CCR98_RS09585	COG0531	amino acid
CCR98_RS09590	COG0531	amino acid
CCR98_RS09600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCR98_RS09605	COG0277	FAD linked oxidase domain protein
CCR98_RS09620	COG2205	protein histidine kinase activity
CCR98_RS09625	COG0745	RESPONSE REGULATOR receiver
CCR98_RS09630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS09635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS09655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCR98_RS09700	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCR98_RS09715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCR98_RS09720	COG0505	Belongs to the CarA family
CCR98_RS09725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCR98_RS09730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCR98_RS09740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCR98_RS09750	COG4676	Protein conserved in bacteria
CCR98_RS09775	COG1012	belongs to the aldehyde dehydrogenase family
CCR98_RS09795	COG0784	Response regulator, receiver
CCR98_RS09795	COG2198	Histidine kinase
CCR98_RS09795	COG2205	protein histidine kinase activity
CCR98_RS09800	COG1024	Enoyl-CoA hydratase
CCR98_RS09805	COG0318	PFAM AMP-dependent synthetase and ligase
CCR98_RS09810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CCR98_RS09815	COG1012	belongs to the aldehyde dehydrogenase family
CCR98_RS09820	COG1309	transcriptional regulator
CCR98_RS09825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCR98_RS09860	COG2267	carboxylic ester hydrolase activity
CCR98_RS09870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCR98_RS09885	COG0840	transmembrane signaling receptor activity
CCR98_RS09895	COG0835	chemotaxis
CCR98_RS09900	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CCR98_RS09905	COG0840	transmembrane signaling receptor activity
CCR98_RS09915	COG0745	RESPONSE REGULATOR receiver
CCR98_RS09925	COG0835	chemotaxis
CCR98_RS09935	COG1360	Flagellar Motor Protein
CCR98_RS09940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CCR98_RS09945	COG2198	Histidine kinase
CCR98_RS09945	COG0643	Histidine kinase
CCR98_RS09945	COG0784	Response regulator, receiver
CCR98_RS09950	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCR98_RS09975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCR98_RS09980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCR98_RS09995	COG1987	bacterial-type flagellum assembly
CCR98_RS10005	COG3190	flagellar
CCR98_RS10055	COG1677	Flagellar hook-basal body complex protein FliE
CCR98_RS10080	COG2197	response regulator
CCR98_RS10100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CCR98_RS10125	COG1256	bacterial-type flagellum assembly
CCR98_RS10140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CCR98_RS10150	COG4787	bacterial-type flagellum-dependent cell motility
CCR98_RS10170	COG1815	bacterial-type flagellum-dependent cell motility
CCR98_RS10175	COG0784	Response regulator, receiver
CCR98_RS10175	COG0835	chemotaxis
CCR98_RS10195	COG5002	protein histidine kinase activity
CCR98_RS10235	COG2915	High frequency lysogenization protein hflD homolog
CCR98_RS10240	COG0482	sulfurtransferase activity
CCR98_RS10255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCR98_RS10265	COG0542	response to heat
CCR98_RS10300	COG0492	ferredoxin-NADP+ reductase activity
CCR98_RS10305	COG1674	ftsk spoiiie
CCR98_RS10320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCR98_RS10325	COG3152	Membrane
CCR98_RS10335	COG2819	hydrolase of the alpha beta superfamily
CCR98_RS10345	COG4558	Periplasmic binding protein
CCR98_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCR98_RS10355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CCR98_RS10365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCR98_RS10380	COG0784	Response regulator, receiver
CCR98_RS10380	COG5002	protein histidine kinase activity
CCR98_RS10410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCR98_RS10420	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CCR98_RS10435	COG1595	DNA-templated transcription, initiation
CCR98_RS10455	COG0784	Response regulator, receiver
CCR98_RS10460	COG4251	negative regulation of phosphorylation
CCR98_RS10470	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CCR98_RS10480	COG0456	acetyltransferase
CCR98_RS10480	COG0454	-acetyltransferase
CCR98_RS10510	COG0431	NADPH-dependent FMN reductase
CCR98_RS10525	COG0798	PFAM Bile acid sodium symporter
CCR98_RS10530	COG0492	ferredoxin-NADP+ reductase activity
CCR98_RS10535	COG2072	flavoprotein involved in K transport
CCR98_RS10550	COG2608	mercury ion transmembrane transporter activity
CCR98_RS10570	COG0789	Transcriptional regulator
CCR98_RS10670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS10675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS10800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CCR98_RS10805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CCR98_RS10810	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CCR98_RS10815	COG2080	2 iron, 2 sulfur cluster binding
CCR98_RS10825	COG0784	Response regulator, receiver
CCR98_RS10825	COG4191	Histidine kinase
CCR98_RS10830	COG0745	RESPONSE REGULATOR receiver
CCR98_RS10845	COG1764	response to oxidative stress
CCR98_RS10855	COG0583	DNA-binding transcription factor activity
CCR98_RS10875	COG1595	DNA-templated transcription, initiation
CCR98_RS10880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCR98_RS10890	COG1309	transcriptional regulator
CCR98_RS10920	COG3685	Protein conserved in bacteria
CCR98_RS10940	COG3685	Protein conserved in bacteria
CCR98_RS10955	COG2200	EAL domain
CCR98_RS10965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCR98_RS10985	COG1063	alcohol dehydrogenase
CCR98_RS11025	COG0667	Aldo Keto reductase
CCR98_RS11055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCR98_RS11060	COG0583	DNA-binding transcription factor activity
CCR98_RS11135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCR98_RS11155	COG0583	DNA-binding transcription factor activity
CCR98_RS11255	COG3604	Transcriptional regulator
CCR98_RS11295	COG5002	protein histidine kinase activity
CCR98_RS11295	COG5001	Diguanylate cyclase
CCR98_RS11295	COG3447	MASE1 domain protein
CCR98_RS11305	COG0577	efflux transmembrane transporter activity
CCR98_RS11305	COG1136	(ABC) transporter
CCR98_RS11310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS11320	COG2205	protein histidine kinase activity
CCR98_RS11330	COG3214	Protein conserved in bacteria
CCR98_RS11340	COG4774	siderophore transport
CCR98_RS11370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCR98_RS11375	COG1285	pathogenesis
CCR98_RS11380	COG4191	Histidine kinase
CCR98_RS11385	COG4566	intracellular signal transduction
CCR98_RS11435	COG0243	molybdopterin cofactor binding
CCR98_RS11500	COG0583	DNA-binding transcription factor activity
CCR98_RS11505	COG0656	L-ascorbic acid biosynthetic process
CCR98_RS11525	COG5002	protein histidine kinase activity
CCR98_RS11530	COG0583	DNA-binding transcription factor activity
CCR98_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS11560	COG0642	Histidine kinase
CCR98_RS11565	COG3537	Alpha-1,2-mannosidase
CCR98_RS11590	COG0477	Major facilitator Superfamily
CCR98_RS11605	COG3920	Histidine kinase
CCR98_RS11605	COG2202	Pas domain
CCR98_RS11640	COG4771	TonB-dependent receptor
CCR98_RS11645	COG1429	ligase activity, forming nitrogen-metal bonds
CCR98_RS11670	COG1335	isochorismatase
CCR98_RS11675	COG1335	isochorismatase
CCR98_RS11705	COG0811	peptide transport
CCR98_RS11825	COG0840	transmembrane signaling receptor activity
CCR98_RS11830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCR98_RS11835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCR98_RS11840	COG4149	molybdate abc transporter
CCR98_RS11845	COG0725	ABC transporter, periplasmic molybdate-binding protein
CCR98_RS11850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCR98_RS11865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCR98_RS11870	COG2181	nitrate reductase activity
CCR98_RS11875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CCR98_RS11880	COG1140	nitrate reductase beta subunit
CCR98_RS11885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CCR98_RS11890	COG2223	nitrite transmembrane transporter activity
CCR98_RS11900	COG0746	molybdenum cofactor guanylyltransferase activity
CCR98_RS11905	COG0314	molybdopterin synthase activity
CCR98_RS11915	COG0303	'Molybdopterin
CCR98_RS11920	COG0315	cyclic pyranopterin monophosphate synthase activity
CCR98_RS11920	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCR98_RS11925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCR98_RS11990	COG0789	Transcriptional regulator
CCR98_RS11995	COG0431	NADPH-dependent FMN reductase
CCR98_RS12005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCR98_RS12010	COG0798	PFAM Bile acid sodium symporter
CCR98_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS12090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CCR98_RS12090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCR98_RS12095	COG1535	isochorismatase
CCR98_RS12095	COG3433	isochorismatase activity
CCR98_RS12100	COG1535	isochorismatase
CCR98_RS12100	COG3433	isochorismatase activity
CCR98_RS12105	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCR98_RS12120	COG2409	Drug exporters of the RND superfamily
CCR98_RS12125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCR98_RS12185	COG1914	H( )-stimulated, divalent metal cation uptake system
CCR98_RS12200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCR98_RS12205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCR98_RS12215	COG4206	TonB-dependent receptor
CCR98_RS12220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCR98_RS12265	COG4772	TonB-dependent receptor
CCR98_RS12285	COG2226	methyltransferase
CCR98_RS12330	COG4964	Belongs to the GSP D family
CCR98_RS12385	COG2814	Major facilitator Superfamily
CCR98_RS12395	COG1228	amidohydrolase
CCR98_RS12405	COG1335	isochorismatase
CCR98_RS12420	COG3850	Histidine kinase
CCR98_RS12425	COG2197	response regulator
CCR98_RS12430	COG2814	Major facilitator Superfamily
CCR98_RS12440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCR98_RS12450	COG0583	DNA-binding transcription factor activity
CCR98_RS12465	COG3161	chorismate lyase activity
CCR98_RS12480	COG2134	cdp-diacylglycerol pyrophosphatase
CCR98_RS12500	COG0277	FAD linked oxidase domain protein
CCR98_RS12505	COG1304	FMN binding
CCR98_RS12510	COG2186	Transcriptional regulator
CCR98_RS12520	COG1285	pathogenesis
CCR98_RS12600	COG0587	DNA-directed DNA polymerase activity
CCR98_RS12615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCR98_RS12635	COG1595	DNA-templated transcription, initiation
CCR98_RS12645	COG4206	TonB-dependent receptor
CCR98_RS12645	COG1629	transport
CCR98_RS12675	COG0531	amino acid
CCR98_RS12690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCR98_RS12790	COG5002	protein histidine kinase activity
CCR98_RS12790	COG5001	Diguanylate cyclase
CCR98_RS12790	COG3447	MASE1 domain protein
CCR98_RS12795	COG2183	response to ionizing radiation
CCR98_RS12820	COG3243	poly(R)-hydroxyalkanoic acid synthase
CCR98_RS12840	COG0534	Mate efflux family protein
CCR98_RS12860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CCR98_RS12870	COG0668	transmembrane transport
CCR98_RS12875	COG1902	pentaerythritol trinitrate reductase activity
CCR98_RS12885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCR98_RS12895	COG1733	regulation of RNA biosynthetic process
CCR98_RS12900	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCR98_RS12905	COG0456	acetyltransferase
CCR98_RS13005	COG3702	type iv secretory pathway
CCR98_RS13025	COG2948	multi-organism process
CCR98_RS13035	COG3736	Type IV secretory pathway, component VirB8
CCR98_RS13045	COG3505	Type IV secretory pathway VirD4
CCR98_RS13055	COG2814	Major facilitator Superfamily
CCR98_RS13095	COG4774	siderophore transport
CCR98_RS13115	COG1733	regulation of RNA biosynthetic process
CCR98_RS13120	COG0604	alcohol dehydrogenase
CCR98_RS13135	COG0210	DNA helicase
CCR98_RS13150	COG0583	DNA-binding transcription factor activity
CCR98_RS13155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCR98_RS13165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCR98_RS13180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCR98_RS13185	COG1605	Chorismate mutase
CCR98_RS13185	COG0077	Prephenate dehydratase
CCR98_RS13190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCR98_RS13235	COG1228	amidohydrolase
CCR98_RS13250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CCR98_RS13295	COG2957	Belongs to the agmatine deiminase family
CCR98_RS13300	COG0583	DNA-binding transcription factor activity
CCR98_RS13375	COG4993	Dehydrogenase
CCR98_RS13385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CCR98_RS13395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CCR98_RS13405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCR98_RS13410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCR98_RS13425	COG0359	binds to the 23S rRNA
CCR98_RS13430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCR98_RS13435	COG0360	Binds together with S18 to 16S ribosomal RNA
CCR98_RS13445	COG0316	Belongs to the HesB IscA family
CCR98_RS13450	COG0017	Asparaginyl-tRNA synthetase
CCR98_RS13470	COG0288	reversible hydration of carbon dioxide
CCR98_RS13480	COG3844	kynureninase activity
CCR98_RS13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCR98_RS13490	COG2925	Exonuclease
CCR98_RS13500	COG0667	Aldo Keto reductase
CCR98_RS13530	COG2902	Dehydrogenase
CCR98_RS13540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS13545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS13560	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS13575	COG0646	methionine synthase
CCR98_RS13575	COG1410	methionine synthase
CCR98_RS13590	COG2900	Belongs to the SlyX family
CCR98_RS13605	COG0386	Belongs to the glutathione peroxidase family
CCR98_RS13615	COG1725	Transcriptional regulator
CCR98_RS13620	COG1131	(ABC) transporter
CCR98_RS13655	COG2850	peptidyl-arginine hydroxylation
CCR98_RS13665	COG0567	Dehydrogenase, E1 component
CCR98_RS13690	COG3540	Alkaline phosphatase
CCR98_RS13700	COG0305	Participates in initiation and elongation during chromosome replication
CCR98_RS13710	COG0367	asparagine synthase
CCR98_RS13720	COG0625	glutathione transferase activity
CCR98_RS13740	COG0084	hydrolase, TatD family'
CCR98_RS13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCR98_RS13780	COG0625	glutathione transferase activity
CCR98_RS13795	COG1595	DNA-templated transcription, initiation
CCR98_RS13800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCR98_RS13815	COG0386	Belongs to the glutathione peroxidase family
CCR98_RS13820	COG0339	signal peptide processing
CCR98_RS13825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCR98_RS13845	COG0705	Rhomboid family
CCR98_RS13850	COG3104	oligopeptide transport
CCR98_RS13860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCR98_RS13865	COG4290	ribonuclease
CCR98_RS13880	COG0316	Belongs to the HesB IscA family
CCR98_RS13880	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CCR98_RS13885	COG2154	pterin-4-alpha-carbinolamine dehydratase
CCR98_RS13895	COG0428	transporter
CCR98_RS13905	COG1530	ribonuclease E activity
CCR98_RS13920	COG0395	ABC-type sugar transport system, permease component
CCR98_RS13945	COG1609	Transcriptional regulator
CCR98_RS13950	COG0271	Belongs to the BolA IbaG family
CCR98_RS13955	COG2350	Protein conserved in bacteria
CCR98_RS13960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCR98_RS13965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCR98_RS13970	COG1187	pseudouridine synthase activity
CCR98_RS13980	COG2814	Major facilitator Superfamily
CCR98_RS14000	COG0436	Aminotransferase
CCR98_RS14005	COG4133	protoheme IX ABC transporter activity
CCR98_RS14025	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CCR98_RS14030	COG1138	Cytochrome C-type biogenesis protein
CCR98_RS14040	COG4235	cytochrome complex assembly
CCR98_RS14040	COG3088	subunit of a heme lyase
CCR98_RS14050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCR98_RS14060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CCR98_RS14065	COG4988	ABC transporter
CCR98_RS14075	COG1294	oxidase, subunit
CCR98_RS14105	COG0726	polysaccharide deacetylase
CCR98_RS14105	COG1649	PFAM Uncharacterised BCR, COG1649
CCR98_RS14110	COG1215	transferase activity, transferring glycosyl groups
CCR98_RS14120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCR98_RS14135	COG0165	Argininosuccinate lyase
CCR98_RS14140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCR98_RS14150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCR98_RS14155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCR98_RS14160	COG0137	argininosuccinate synthase activity
CCR98_RS14165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCR98_RS14180	COG2166	iron-sulfur cluster assembly
CCR98_RS14200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCR98_RS14220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCR98_RS14225	COG0402	S-adenosylhomocysteine deaminase activity
CCR98_RS14230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCR98_RS14235	COG1509	lysine 2,3-aminomutase activity
CCR98_RS14240	COG3300	MHYT domain
CCR98_RS14240	COG5001	Diguanylate cyclase
CCR98_RS14260	COG0501	Belongs to the peptidase M48B family
CCR98_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS14290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCR98_RS14295	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCR98_RS14300	COG0802	atpase or kinase
CCR98_RS14305	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCR98_RS14305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCR98_RS14310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCR98_RS14315	COG1570	exodeoxyribonuclease VII activity
CCR98_RS14325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCR98_RS14340	COG4771	TonB-dependent receptor
CCR98_RS14360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCR98_RS14360	COG2169	Transcriptional regulator
CCR98_RS14365	COG2130	NADP-dependent
CCR98_RS14390	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS14400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCR98_RS14415	COG2197	response regulator
CCR98_RS14475	COG1309	transcriptional regulator
CCR98_RS14480	COG2076	Multidrug Resistance protein
CCR98_RS14485	COG5487	UPF0391 membrane protein
CCR98_RS14490	COG1280	lysine exporter protein (LysE YggA)
CCR98_RS14495	COG0740	serine-type endopeptidase activity
CCR98_RS14505	COG0640	Transcriptional regulator
CCR98_RS14510	COG1794	racemase activity, acting on amino acids and derivatives
CCR98_RS14530	COG0456	acetyltransferase
CCR98_RS14530	COG0454	-acetyltransferase
CCR98_RS14545	COG0776	regulation of translation
CCR98_RS14550	COG0072	phenylalanine-tRNA ligase activity
CCR98_RS14550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCR98_RS14555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCR98_RS14560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCR98_RS14565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCR98_RS14570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCR98_RS14575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCR98_RS14600	COG1185	polyribonucleotide nucleotidyltransferase activity
CCR98_RS14605	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCR98_RS14615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCR98_RS14620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCR98_RS14625	COG0195	Participates in both transcription termination and antitermination
CCR98_RS14630	COG0779	Required for maturation of 30S ribosomal subunits
CCR98_RS14645	COG1007	ATP synthesis coupled electron transport
CCR98_RS14660	COG0713	ATP synthesis coupled electron transport
CCR98_RS14670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCR98_RS14675	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCR98_RS14690	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CCR98_RS14695	COG0649	NAD binding
CCR98_RS14700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCR98_RS14705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCR98_RS14710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCR98_RS14725	COG0149	triose-phosphate isomerase activity
CCR98_RS14735	COG3119	arylsulfatase activity
CCR98_RS14740	COG0438	transferase activity, transferring glycosyl groups
CCR98_RS14745	COG0726	polysaccharide deacetylase
CCR98_RS14750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCR98_RS14755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCR98_RS14760	COG0159	tryptophan synthase activity
CCR98_RS14770	COG0133	tryptophan synthase activity
CCR98_RS14805	COG0135	phosphoribosylanthranilate isomerase activity
CCR98_RS14810	COG0101	tRNA pseudouridine synthase activity
CCR98_RS14825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCR98_RS14830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCR98_RS14835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCR98_RS14840	COG2890	protein-(glutamine-N5) methyltransferase activity
CCR98_RS14845	COG1999	signal sequence binding
CCR98_RS14850	COG0688	phosphatidylethanolamine metabolic process
CCR98_RS14865	COG0433	COG0433 Predicted ATPase
CCR98_RS14870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCR98_RS14880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCR98_RS14930	COG0412	Dienelactone hydrolase
CCR98_RS14945	COG0717	Belongs to the dCTP deaminase family
CCR98_RS14955	COG0489	protein tyrosine kinase activity
CCR98_RS14960	COG4771	TonB-dependent receptor
CCR98_RS14965	COG4771	TonB-dependent receptor
CCR98_RS14970	COG4206	TonB-dependent receptor
CCR98_RS14975	COG3590	peptidase
CCR98_RS15005	COG0697	spore germination
CCR98_RS15015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCR98_RS15020	COG2311	Membrane
CCR98_RS15025	COG1047	Peptidyl-prolyl cis-trans
CCR98_RS15030	COG0791	NLP P60 protein
CCR98_RS15035	COG0791	NLP P60 protein
CCR98_RS15040	COG1301	dicarboxylic acid transport
CCR98_RS15060	COG1722	exodeoxyribonuclease VII activity
CCR98_RS15065	COG0142	geranyltranstransferase activity
CCR98_RS15075	COG0312	modulator of DNA gyrase
CCR98_RS15080	COG3028	Belongs to the UPF0307 family
CCR98_RS15085	COG0312	modulator of DNA gyrase
CCR98_RS15105	COG2968	Membrane
CCR98_RS15115	COG4771	TonB-dependent receptor
CCR98_RS15135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCR98_RS15145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCR98_RS15160	COG0495	leucyl-tRNA aminoacylation
CCR98_RS15175	COG3118	belongs to the thioredoxin family
CCR98_RS15185	COG2203	Gaf domain
CCR98_RS15185	COG4251	negative regulation of phosphorylation
CCR98_RS15185	COG5001	Diguanylate cyclase
CCR98_RS15185	COG3706	GGDEF domain
CCR98_RS15210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CCR98_RS15220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCR98_RS15225	COG0346	lactoylglutathione lyase activity
CCR98_RS15235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCR98_RS15235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCR98_RS15245	COG2878	Part of a membrane complex involved in electron transport
CCR98_RS15250	COG0251	oxidation-reduction process
CCR98_RS15255	COG0392	lysyltransferase activity
CCR98_RS15255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CCR98_RS15285	COG2824	Alkylphosphonate utilization operon protein PhnA
CCR98_RS15290	COG0443	Heat shock 70 kDa protein
CCR98_RS15330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCR98_RS15335	COG3122	Protein conserved in bacteria
CCR98_RS15340	COG1451	nucleotide metabolic process
CCR98_RS15350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCR98_RS15370	COG0183	Belongs to the thiolase family
CCR98_RS15385	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS15395	COG1793	dna ligase
CCR98_RS15400	COG1201	RNA secondary structure unwinding
CCR98_RS15415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCR98_RS15420	COG1278	Cold shock
CCR98_RS15425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CCR98_RS15430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CCR98_RS15435	COG1472	Belongs to the glycosyl hydrolase 3 family
CCR98_RS15440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CCR98_RS15445	COG2954	triphosphatase activity
CCR98_RS15450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCR98_RS15460	COG1381	Involved in DNA repair and RecF pathway recombination
CCR98_RS15465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCR98_RS15480	COG0681	Belongs to the peptidase S26 family
CCR98_RS15485	COG0481	GTPase activity
CCR98_RS15490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCR98_RS15510	COG1741	Belongs to the pirin family
CCR98_RS15515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCR98_RS15525	COG1741	Belongs to the pirin family
CCR98_RS15535	COG1966	Carbon starvation protein
CCR98_RS15540	COG2879	small protein
CCR98_RS15555	COG2205	protein histidine kinase activity
CCR98_RS15595	COG2814	Major facilitator Superfamily
CCR98_RS15600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCR98_RS15600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCR98_RS15610	COG1113	amino acid transport
CCR98_RS15615	COG2207	Transcriptional regulator
CCR98_RS15615	COG1917	Cupin 2, conserved barrel domain protein
CCR98_RS15620	COG0753	catalase activity
CCR98_RS15650	COG1376	ErfK ybiS ycfS ynhG family protein
CCR98_RS15655	COG0739	heme binding
CCR98_RS15665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCR98_RS15675	COG0330	HflC and HflK could
CCR98_RS15680	COG0330	HflC and HflK could
CCR98_RS15685	COG0604	alcohol dehydrogenase
CCR98_RS15700	COG0678	peroxiredoxin activity
CCR98_RS15710	COG4953	penicillin-binding protein 1C
CCR98_RS15715	COG2373	Large extracellular alpha-helical protein
CCR98_RS15725	COG2079	MmgE PrpD family protein
CCR98_RS15730	COG2828	Protein conserved in bacteria
CCR98_RS15740	COG3609	addiction module antidote protein, CC2985 family
CCR98_RS15775	COG0259	pyridoxamine-phosphate oxidase activity
CCR98_RS15790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCR98_RS15810	COG0477	Major facilitator Superfamily
CCR98_RS15820	COG0784	Response regulator, receiver
CCR98_RS15820	COG2205	protein histidine kinase activity
CCR98_RS15820	COG2198	Histidine kinase
CCR98_RS15830	COG3038	cytochrome b561
CCR98_RS15845	COG1760	l-serine dehydratase
CCR98_RS15855	COG0460	homoserine dehydrogenase
CCR98_RS15855	COG0527	aspartate kinase activity
CCR98_RS15860	COG0626	cystathionine gamma-synthase activity
CCR98_RS15865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCR98_RS15870	COG0739	heme binding
CCR98_RS15875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCR98_RS15880	COG1272	protein, Hemolysin III
CCR98_RS15885	COG2982	Protein involved in outer membrane biogenesis
CCR98_RS15895	COG0463	Glycosyl transferase, family 2
CCR98_RS15900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCR98_RS15905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCR98_RS15915	COG4206	TonB-dependent receptor
CCR98_RS15920	COG1309	transcriptional regulator
CCR98_RS15930	COG1960	acyl-CoA dehydrogenase activity
CCR98_RS15965	COG0583	DNA-binding transcription factor activity
CCR98_RS15975	COG0509	glycine decarboxylation via glycine cleavage system
CCR98_RS15980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CCR98_RS15995	COG3956	TIGRFAM MazG family protein
CCR98_RS16000	COG1218	3'(2'),5'-bisphosphate nucleotidase
CCR98_RS16005	COG0494	nUDIX hydrolase
CCR98_RS16015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCR98_RS16030	COG0784	Response regulator, receiver
CCR98_RS16030	COG0643	Histidine kinase
CCR98_RS16030	COG2198	Histidine kinase
CCR98_RS16035	COG0840	transmembrane signaling receptor activity
CCR98_RS16040	COG0835	chemotaxis
CCR98_RS16055	COG0189	ligase activity
CCR98_RS16065	COG1214	PFAM Peptidase M22, glycoprotease
CCR98_RS16070	COG1199	ATP-dependent helicase activity
CCR98_RS16080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCR98_RS16090	COG1215	transferase activity, transferring glycosyl groups
CCR98_RS16100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCR98_RS16110	COG1643	Atp-dependent helicase
CCR98_RS16115	COG0783	Belongs to the Dps family
CCR98_RS16120	COG0514	ATP-dependent DNA helicase (RecQ)
CCR98_RS16130	COG2132	Multicopper oxidase
CCR98_RS16220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCR98_RS16225	COG0602	queuosine metabolic process
CCR98_RS16235	COG2885	chlorophyll binding
CCR98_RS16240	COG0823	Involved in the tonB-independent uptake of proteins
CCR98_RS16255	COG0811	peptide transport
CCR98_RS16260	COG0824	Thioesterase
CCR98_RS16265	COG2255	four-way junction helicase activity
CCR98_RS16275	COG0632	four-way junction helicase activity
CCR98_RS16280	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCR98_RS16285	COG0217	transcriptional regulatory protein
CCR98_RS16305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCR98_RS16335	COG0488	(ABC) transporter
CCR98_RS16345	COG4651	solute:proton antiporter activity
CCR98_RS16345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCR98_RS16355	COG0745	RESPONSE REGULATOR receiver
CCR98_RS16360	COG2205	protein histidine kinase activity
CCR98_RS16370	COG0542	response to heat
CCR98_RS16390	COG0028	Belongs to the TPP enzyme family
CCR98_RS16415	COG3387	PFAM Glycoside hydrolase 15-related
CCR98_RS16420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CCR98_RS16425	COG3011	Protein conserved in bacteria
CCR98_RS16440	COG0564	pseudouridine synthase activity
CCR98_RS16445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCR98_RS16455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCR98_RS16455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCR98_RS16465	COG0045	succinate-CoA ligase (ADP-forming) activity
CCR98_RS16505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCR98_RS16530	COG2205	protein histidine kinase activity
CCR98_RS16535	COG0745	RESPONSE REGULATOR receiver
CCR98_RS16555	COG0189	ligase activity
CCR98_RS16580	COG3152	Membrane
CCR98_RS16590	COG4625	pathogenesis
CCR98_RS16590	COG3240	lipase activity
CCR98_RS16600	COG2022	thiamine diphosphate biosynthetic process
CCR98_RS16605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCR98_RS16610	COG0471	metal ion transport
CCR98_RS16610	COG3273	potassium ion transport
CCR98_RS16630	COG1970	mechanosensitive ion channel activity
CCR98_RS16640	COG1115	amino acid carrier protein
CCR98_RS16650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCR98_RS16655	COG1115	amino acid carrier protein
CCR98_RS16660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCR98_RS16665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS16670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS16695	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CCR98_RS16705	COG3588	fructose-bisphosphate aldolase
CCR98_RS16710	COG0469	pyruvate kinase activity
CCR98_RS16720	COG0126	phosphoglycerate kinase activity
CCR98_RS16735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCR98_RS16785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCR98_RS16790	COG1301	dicarboxylic acid transport
CCR98_RS16800	COG2304	oxidoreductase activity
CCR98_RS16820	COG0714	Associated with various cellular activities
CCR98_RS16850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CCR98_RS16865	COG5295	Hep Hag repeat protein
CCR98_RS16900	COG0254	rRNA binding
CCR98_RS16910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCR98_RS16920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCR98_RS16925	COG1758	RNA polymerase activity
CCR98_RS16935	COG3383	formate dehydrogenase (NAD+) activity
CCR98_RS16935	COG0243	molybdopterin cofactor binding
CCR98_RS16940	COG3383	formate dehydrogenase (NAD+) activity
CCR98_RS16940	COG0243	molybdopterin cofactor binding
CCR98_RS16945	COG0437	4 iron, 4 sulfur cluster binding
CCR98_RS16950	COG2864	formate dehydrogenase
CCR98_RS16960	COG1921	L-seryl-tRNASec selenium transferase activity
CCR98_RS16965	COG3276	selenocysteine insertion sequence binding
CCR98_RS16975	COG0709	Synthesizes selenophosphate from selenide and ATP
CCR98_RS16980	COG1561	YicC-like family, N-terminal region
CCR98_RS16985	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CCR98_RS16990	COG0346	lactoylglutathione lyase activity
CCR98_RS17000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCR98_RS17015	COG0006	proline dipeptidase activity
CCR98_RS17020	COG0006	proline dipeptidase activity
CCR98_RS17025	COG3079	Belongs to the UPF0149 family
CCR98_RS17045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCR98_RS17055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCR98_RS17065	COG2912	Transglutaminase-like superfamily
CCR98_RS17080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCR98_RS17085	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CCR98_RS17095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCR98_RS17100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCR98_RS17115	COG4221	oxidoreductase activity
CCR98_RS17135	COG0671	phosphoesterase, PA-phosphatase related
CCR98_RS17145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCR98_RS17150	COG0563	adenylate kinase activity
CCR98_RS17175	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CCR98_RS17190	COG0848	biopolymer transport protein
CCR98_RS17200	COG2832	Protein of unknown function (DUF454)
CCR98_RS17240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCR98_RS17265	COG0745	RESPONSE REGULATOR receiver
CCR98_RS17275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCR98_RS17280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCR98_RS17285	COG0405	Gamma-glutamyltransferase
CCR98_RS17290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCR98_RS17310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCR98_RS17315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCR98_RS17330	COG0473	3-isopropylmalate dehydrogenase activity
CCR98_RS17360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCR98_RS17365	COG1538	Outer membrane efflux protein
CCR98_RS17375	COG1519	Transferase
CCR98_RS17380	COG1560	Kdo2-lipid A biosynthetic process
CCR98_RS17385	COG1943	Transposase
CCR98_RS17420	COG1301	dicarboxylic acid transport
CCR98_RS17430	COG4191	Histidine kinase
CCR98_RS17445	COG0642	Histidine kinase
CCR98_RS17460	COG2851	Citrate transporter
CCR98_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS17480	COG1162	GTPase activity
CCR98_RS17485	COG0436	Aminotransferase
CCR98_RS17505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCR98_RS17520	COG1228	amidohydrolase
CCR98_RS17525	COG0804	urea catabolic process
CCR98_RS17535	COG1307	EDD domain protein, DegV family
CCR98_RS17575	COG5001	Diguanylate cyclase
CCR98_RS17575	COG4251	negative regulation of phosphorylation
CCR98_RS17575	COG3706	GGDEF domain
CCR98_RS17575	COG2203	Gaf domain
CCR98_RS17585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CCR98_RS17600	COG1902	pentaerythritol trinitrate reductase activity
CCR98_RS17615	COG0583	DNA-binding transcription factor activity
CCR98_RS17620	COG1064	alcohol dehydrogenase
CCR98_RS17645	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCR98_RS17650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCR98_RS17660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCR98_RS17665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCR98_RS17680	COG1522	sequence-specific DNA binding
CCR98_RS17690	COG4773	Receptor
CCR98_RS17720	COG0617	tRNA 3'-terminal CCA addition
CCR98_RS17755	COG3468	outer membrane autotransporter barrel domain protein
CCR98_RS17765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCR98_RS17770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCR98_RS17775	COG1609	Transcriptional regulator
CCR98_RS17785	COG0837	glucose binding
CCR98_RS17795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CCR98_RS17815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCR98_RS17825	COG4191	Histidine kinase
CCR98_RS17830	COG0784	Response regulator, receiver
CCR98_RS17835	COG4251	negative regulation of phosphorylation
CCR98_RS17840	COG2823	Periplasmic or secreted lipoprotein
CCR98_RS17845	COG0673	inositol 2-dehydrogenase activity
CCR98_RS17855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CCR98_RS17875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCR98_RS17880	COG0321	lipoyl(octanoyl) transferase activity
CCR98_RS17885	COG2921	Belongs to the UPF0250 family
CCR98_RS17895	COG1686	Belongs to the peptidase S11 family
CCR98_RS17900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCR98_RS17905	COG2951	lytic endotransglycosylase activity
CCR98_RS17910	COG0772	Belongs to the SEDS family
CCR98_RS17915	COG0772	Belongs to the SEDS family
CCR98_RS17920	COG0768	penicillin binding
CCR98_RS17930	COG1792	Involved in formation and maintenance of cell shape
CCR98_RS17935	COG1077	Cell shape determining protein MreB Mrl
CCR98_RS17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCR98_RS17955	COG0308	aminopeptidase N
CCR98_RS17960	COG2226	methyltransferase
CCR98_RS17985	COG1943	Transposase
CCR98_RS17990	COG1538	Outer membrane efflux protein
CCR98_RS17995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS18000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS18010	COG0673	inositol 2-dehydrogenase activity
CCR98_RS18020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CCR98_RS18040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CCR98_RS18050	COG2832	Protein of unknown function (DUF454)
CCR98_RS18060	COG0436	Aminotransferase
CCR98_RS18065	COG1505	serine-type exopeptidase activity
CCR98_RS18100	COG0697	spore germination
CCR98_RS18105	COG1666	GTP binding
CCR98_RS18120	COG0339	signal peptide processing
CCR98_RS18130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCR98_RS18150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCR98_RS18160	COG1136	(ABC) transporter
CCR98_RS18165	COG1136	(ABC) transporter
CCR98_RS18165	COG0577	efflux transmembrane transporter activity
CCR98_RS18170	COG0577	efflux transmembrane transporter activity
CCR98_RS18170	COG1136	(ABC) transporter
CCR98_RS18185	COG4191	Histidine kinase
CCR98_RS18195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCR98_RS18210	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCR98_RS18215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCR98_RS18220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCR98_RS18225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCR98_RS18230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCR98_RS18235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCR98_RS18245	COG0356	it plays a direct role in the translocation of protons across the membrane
CCR98_RS18260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCR98_RS18265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCR98_RS18285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCR98_RS18310	COG0181	hydroxymethylbilane synthase activity
CCR98_RS18320	COG0745	RESPONSE REGULATOR receiver
CCR98_RS18320	COG2972	Histidine kinase
CCR98_RS18325	COG0400	carboxylic ester hydrolase activity
CCR98_RS18340	COG4771	TonB-dependent receptor
CCR98_RS18350	COG0840	transmembrane signaling receptor activity
CCR98_RS18415	COG0625	glutathione transferase activity
CCR98_RS18430	COG2259	Doxx family
CCR98_RS18455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCR98_RS18460	COG1490	D-aminoacyl-tRNA deacylase activity
CCR98_RS18505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCR98_RS18505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCR98_RS18510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCR98_RS18515	COG0242	peptide deformylase activity
CCR98_RS18525	COG0758	DNA mediated transformation
CCR98_RS18530	COG2922	Belongs to the Smg family
CCR98_RS18540	COG1714	RDD family
CCR98_RS18545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCR98_RS18545	COG1754	DNA topoisomerase type I activity
CCR98_RS18550	COG0009	L-threonylcarbamoyladenylate synthase
CCR98_RS18565	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS18575	COG0616	signal peptide processing
CCR98_RS18580	COG0534	Mate efflux family protein
CCR98_RS18595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCR98_RS18600	COG0625	glutathione transferase activity
CCR98_RS18610	COG1252	NADH dehydrogenase
CCR98_RS18630	COG2860	membrane
CCR98_RS18635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCR98_RS18655	COG1846	Transcriptional regulator
CCR98_RS18670	COG0459	protein refolding
CCR98_RS18675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCR98_RS18680	COG2356	endonuclease I
CCR98_RS18685	COG1324	tolerance protein
CCR98_RS18695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCR98_RS18705	COG0840	transmembrane signaling receptor activity
CCR98_RS18725	COG0583	DNA-binding transcription factor activity
CCR98_RS18735	COG1785	Belongs to the alkaline phosphatase family
CCR98_RS18740	COG1686	Belongs to the peptidase S11 family
CCR98_RS18750	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCR98_RS18760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CCR98_RS18770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCR98_RS18780	COG0511	ligase activity, forming carbon-carbon bonds
CCR98_RS18785	COG0439	Biotin carboxylase
CCR98_RS18800	COG2264	protein methyltransferase activity
CCR98_RS18810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CCR98_RS18815	COG4589	Belongs to the CDS family
CCR98_RS18820	COG0204	Acyl-transferase
CCR98_RS18830	COG2453	phosphatase
CCR98_RS18830	COG0671	phosphoesterase, PA-phosphatase related
CCR98_RS18835	COG2267	carboxylic ester hydrolase activity
CCR98_RS18840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCR98_RS18845	COG0138	bifunctional purine biosynthesis protein purh
CCR98_RS18850	COG0151	Belongs to the GarS family
CCR98_RS18855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCR98_RS18860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCR98_RS18865	COG2201	protein-glutamate methylesterase activity
CCR98_RS18870	COG2177	Part of the ABC transporter FtsEX involved in
CCR98_RS18875	COG2884	Cell division ATP-binding protein ftsE
CCR98_RS18880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCR98_RS18895	COG3118	belongs to the thioredoxin family
CCR98_RS18900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCR98_RS18905	COG3706	GGDEF domain
CCR98_RS18915	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CCR98_RS18955	COG3209	COG3209 Rhs family protein
CCR98_RS18965	COG1652	LysM domain
CCR98_RS18970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCR98_RS18970	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCR98_RS18975	COG1473	amidohydrolase
CCR98_RS18980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCR98_RS18985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS18990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCR98_RS19000	COG1289	transmembrane transporter activity
CCR98_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS19010	COG2814	Major facilitator Superfamily
CCR98_RS19040	COG0316	Belongs to the HesB IscA family
CCR98_RS19065	COG0784	Response regulator, receiver
CCR98_RS19065	COG2205	protein histidine kinase activity
CCR98_RS19065	COG5002	protein histidine kinase activity
CCR98_RS19080	COG1051	belongs to the nudix hydrolase family
CCR98_RS19095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCR98_RS19100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCR98_RS19105	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CCR98_RS19115	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CCR98_RS19120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCR98_RS19125	COG0730	response to heat
CCR98_RS19135	COG0134	indole-3-glycerol-phosphate synthase activity
CCR98_RS19140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCR98_RS19155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCR98_RS19160	COG1597	lipid kinase activity
CCR98_RS19175	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCR98_RS19180	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCR98_RS19190	COG2111	Na H antiporter
CCR98_RS19190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCR98_RS19195	COG1006	Multisubunit Na H antiporter MnhC subunit
CCR98_RS19200	COG0651	ATP synthesis coupled electron transport
CCR98_RS19205	COG1863	multisubunit Na H antiporter MnhE subunit
CCR98_RS19210	COG2212	antiporter activity
CCR98_RS19215	COG1320	monovalent cation:proton antiporter activity
CCR98_RS19220	COG0530	calcium, potassium:sodium antiporter activity
CCR98_RS19235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CCR98_RS19260	COG3104	oligopeptide transport
CCR98_RS19265	COG3483	tryptophan 2,3-dioxygenase activity
CCR98_RS19295	COG2378	regulation of single-species biofilm formation
CCR98_RS19310	COG2354	Protein conserved in bacteria
CCR98_RS19315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCR98_RS19320	COG1368	sulfuric ester hydrolase activity
CCR98_RS19325	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CCR98_RS19325	COG3264	Mechanosensitive ion channel
CCR98_RS19340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CCR98_RS19375	COG1166	arginine decarboxylase activity
CCR98_RS19380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCR98_RS19405	COG2960	long-chain fatty acid transporting porin activity
CCR98_RS19425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CCR98_RS19430	COG1335	isochorismatase
CCR98_RS19460	COG0606	chelatase, subunit chli
CCR98_RS19475	COG0561	phosphatase activity
CCR98_RS19480	COG3932	Exopolysaccharide synthesis, ExoD
CCR98_RS19510	COG1999	signal sequence binding
CCR98_RS19515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCR98_RS19520	COG1845	cytochrome c oxidase, subunit III
CCR98_RS19530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCR98_RS19535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCR98_RS19550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCR98_RS19555	COG1104	cysteine desulfurase activity
CCR98_RS19600	COG2031	fatty acid transporter
CCR98_RS19620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCR98_RS19650	COG0673	inositol 2-dehydrogenase activity
CCR98_RS19660	COG1501	Belongs to the glycosyl hydrolase 31 family
CCR98_RS19665	COG2222	sugar isomerase
CCR98_RS19670	COG1940	carbohydrate kinase activity
CCR98_RS19680	COG1349	DNA-binding transcription factor activity
CCR98_RS19685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCR98_RS19690	COG2814	Major facilitator Superfamily
CCR98_RS19720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCR98_RS19725	COG0156	8-amino-7-oxononanoate synthase activity
CCR98_RS19730	COG2267	carboxylic ester hydrolase activity
CCR98_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS19750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCR98_RS19765	COG3541	Predicted nucleotidyltransferase
CCR98_RS19770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCR98_RS19795	COG0714	Associated with various cellular activities
CCR98_RS19805	COG0754	glutathionylspermidine amidase activity
CCR98_RS19820	COG0129	dihydroxy-acid dehydratase activity
CCR98_RS19830	COG1199	ATP-dependent helicase activity
CCR98_RS19840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCR98_RS19860	COG3781	membrane
CCR98_RS19890	COG0625	glutathione transferase activity
CCR98_RS19910	COG2207	Transcriptional regulator
CCR98_RS19925	COG4555	ABC transporter
CCR98_RS19985	COG2197	response regulator
CCR98_RS20035	COG1404	Belongs to the peptidase S8 family
CCR98_RS20045	COG0745	RESPONSE REGULATOR receiver
CCR98_RS20105	COG0633	Ferredoxin
CCR98_RS20105	COG0543	2 iron, 2 sulfur cluster binding
CCR98_RS20110	COG1131	(ABC) transporter
CCR98_RS20115	COG0842	Transport permease protein
CCR98_RS20125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCR98_RS20135	COG0084	hydrolase, TatD family'
CCR98_RS20145	COG1643	Atp-dependent helicase
CCR98_RS20155	COG1187	pseudouridine synthase activity
CCR98_RS20170	COG0667	Aldo Keto reductase
CCR98_RS20185	COG1690	Belongs to the RtcB family
CCR98_RS20200	COG0840	transmembrane signaling receptor activity
CCR98_RS20205	COG0656	L-ascorbic acid biosynthetic process
CCR98_RS20210	COG2267	carboxylic ester hydrolase activity
CCR98_RS20215	COG0393	Putative heavy-metal-binding
CCR98_RS20220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCR98_RS20220	COG1042	CoA-binding domain protein
CCR98_RS20220	COG0045	succinate-CoA ligase (ADP-forming) activity
CCR98_RS20225	COG2239	Acts as a magnesium transporter
CCR98_RS20240	COG3177	Filamentation induced by cAMP protein fic
CCR98_RS20240	COG0666	response to abiotic stimulus
CCR98_RS20245	COG3100	YcgL domain-containing protein
CCR98_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
CCR98_RS20280	COG0644	oxidoreductase
CCR98_RS20300	COG2986	histidine ammonia-lyase
CCR98_RS20310	COG0463	Glycosyl transferase, family 2
CCR98_RS20325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCR98_RS20330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCR98_RS20345	COG1294	oxidase, subunit
CCR98_RS20350	COG1271	oxidase subunit
CCR98_RS20360	COG1595	DNA-templated transcription, initiation
CCR98_RS20380	COG0494	nUDIX hydrolase
CCR98_RS20400	COG0408	coproporphyrinogen oxidase activity
CCR98_RS20410	COG2323	membrane
CCR98_RS20425	COG0589	response to stress
CCR98_RS20435	COG0210	DNA helicase
CCR98_RS20445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCR98_RS20455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCR98_RS20460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCR98_RS20465	COG1819	glycosyl
CCR98_RS20480	COG0251	oxidation-reduction process
CCR98_RS20515	COG0463	Glycosyl transferase, family 2
CCR98_RS20530	COG1475	DNA binding
CCR98_RS20535	COG1192	Involved in chromosome partitioning
CCR98_RS20540	COG0357	Ribosomal RNA small subunit methyltransferase G
CCR98_RS20545	COG2091	lysine biosynthetic process via aminoadipic acid
CCR98_RS20585	COG1971	Probably functions as a manganese efflux pump
CCR98_RS20590	COG2205	protein histidine kinase activity
CCR98_RS20590	COG0784	Response regulator, receiver
CCR98_RS20600	COG0443	Heat shock 70 kDa protein
CCR98_RS20615	COG2911	Protein conserved in bacteria
CCR98_RS20620	COG0729	surface antigen
CCR98_RS20630	COG0752	glycyl-tRNA synthetase alpha subunit
CCR98_RS20635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCR98_RS20640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCR98_RS20640	COG0519	Catalyzes the synthesis of GMP from XMP
CCR98_RS20650	COG0805	protein transport
CCR98_RS20660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCR98_RS20670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCR98_RS20680	COG0840	transmembrane signaling receptor activity
CCR98_RS20735	COG3135	benzoate transporter
CCR98_RS20750	COG0676	glucose-6-phosphate 1-epimerase activity
CCR98_RS20755	COG2951	lytic endotransglycosylase activity
CCR98_RS20760	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CCR98_RS20765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCR98_RS20770	COG3706	GGDEF domain
CCR98_RS20800	COG0302	gtp cyclohydrolase
CCR98_RS20825	COG1289	transmembrane transporter activity
CCR98_RS20840	COG1074	ATP-dependent DNA helicase activity
CCR98_RS20845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CCR98_RS20850	COG1127	ABC transporter
CCR98_RS20855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCR98_RS20860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCR98_RS20875	COG2853	Lipoprotein
CCR98_RS20880	COG0386	Belongs to the glutathione peroxidase family
CCR98_RS20890	COG1322	Protein conserved in bacteria
CCR98_RS20905	COG0583	DNA-binding transcription factor activity
CCR98_RS20915	COG0531	amino acid
CCR98_RS20925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCR98_RS20930	COG0861	Integral membrane protein TerC family
CCR98_RS20940	COG0584	glycerophosphoryl diester phosphodiesterase
CCR98_RS20955	COG0706	membrane insertase activity
CCR98_RS20960	COG0594	ribonuclease P activity
CCR98_RS20965	COG0230	Belongs to the bacterial ribosomal protein bL34 family