locus-tag	class	description
SMON_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SMON_RS00010	COG1114	Component of the transport system for branched-chain amino acids
SMON_RS00030	COG3210	domain, Protein
SMON_RS00040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SMON_RS00065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SMON_RS00070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SMON_RS00075	COG1131	(ABC) transporter
SMON_RS00105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SMON_RS00115	COG0488	(ABC) transporter
SMON_RS00120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SMON_RS00125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SMON_RS00130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SMON_RS00135	COG0772	Belongs to the SEDS family
SMON_RS00140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SMON_RS00145	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SMON_RS00165	COG0191	fructose-bisphosphate aldolase activity
SMON_RS00170	COG1263	PTS System
SMON_RS00170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMON_RS00170	COG2190	(PTS) system
SMON_RS00175	COG1940	carbohydrate kinase activity
SMON_RS00190	COG0504	CTP synthase activity
SMON_RS00195	COG2501	S4 domain
SMON_RS00200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SMON_RS00210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SMON_RS00220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SMON_RS00225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SMON_RS00235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SMON_RS00240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SMON_RS00245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SMON_RS00255	COG0138	bifunctional purine biosynthesis protein purh
SMON_RS00260	COG0151	Belongs to the GarS family
SMON_RS00275	COG1523	belongs to the glycosyl hydrolase 13 family
SMON_RS00300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SMON_RS00305	COG0601	transmembrane transport
SMON_RS00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SMON_RS00315	COG0444	Belongs to the ABC transporter superfamily
SMON_RS00320	COG4608	Belongs to the ABC transporter superfamily
SMON_RS00325	COG4166	transmembrane transport
SMON_RS00330	COG1132	(ABC) transporter
SMON_RS00355	COG0802	atpase or kinase
SMON_RS00360	COG1214	PFAM Peptidase M22, glycoprotease
SMON_RS00365	COG0552	protein localization to endoplasmic reticulum
SMON_RS00370	COG0280	phosphate acetyltransferase
SMON_RS00375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SMON_RS00385	COG0716	FMN binding
SMON_RS00390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SMON_RS00390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SMON_RS00400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SMON_RS00440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SMON_RS00445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SMON_RS00460	COG0594	ribonuclease P activity
SMON_RS00465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SMON_RS00470	COG0706	membrane insertase activity
SMON_RS00475	COG1847	R3H domain protein
SMON_RS00480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SMON_RS00490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SMON_RS00510	COG2755	lipolytic protein G-D-S-L family
SMON_RS00510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SMON_RS00540	COG1349	DNA-binding transcription factor activity
SMON_RS00550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS00550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS00550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS00570	COG1609	Transcriptional regulator
SMON_RS00575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SMON_RS00580	COG0800	Aldolase
SMON_RS00585	COG5492	domain, Protein
SMON_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
SMON_RS00595	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SMON_RS00600	COG3842	ATPase activity
SMON_RS00605	COG4209	transmembrane transport
SMON_RS00610	COG0395	ABC-type sugar transport system, permease component
SMON_RS00615	COG1653	transport
SMON_RS00625	COG5492	domain, Protein
SMON_RS00630	COG3119	arylsulfatase activity
SMON_RS00635	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SMON_RS00670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SMON_RS00680	COG4555	ABC transporter
SMON_RS00695	COG3684	Belongs to the aldolase LacD family
SMON_RS00710	COG0395	ABC-type sugar transport system, permease component
SMON_RS00715	COG1175	transmembrane transport
SMON_RS00725	COG5426	von Willebrand factor, type A
SMON_RS00730	COG2222	sugar isomerase
SMON_RS00750	COG3716	PTS system mannose fructose sorbose family IID component
SMON_RS00755	COG3715	PTS system
SMON_RS00760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMON_RS00765	COG3468	outer membrane autotransporter barrel domain protein
SMON_RS00765	COG3210	domain, Protein
SMON_RS00770	COG1301	dicarboxylic acid transport
SMON_RS00775	COG0561	phosphatase activity
SMON_RS00780	COG2201	protein-glutamate methylesterase activity
SMON_RS00785	COG1380	Effector of murein hydrolase LrgA
SMON_RS00790	COG1346	cytolysis
SMON_RS00895	COG2235	arginine
SMON_RS00900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SMON_RS00905	COG0549	Belongs to the carbamate kinase family
SMON_RS00910	COG1288	antiporter activity
SMON_RS00920	COG3468	outer membrane autotransporter barrel domain protein
SMON_RS00920	COG3210	domain, Protein
SMON_RS00925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SMON_RS00930	COG0049	tRNA binding
SMON_RS00935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SMON_RS00940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SMON_RS00945	COG0051	transcription antitermination factor activity, RNA binding
SMON_RS00950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SMON_RS00955	COG0088	Forms part of the polypeptide exit tunnel
SMON_RS00960	COG0089	rRNA binding
SMON_RS00965	COG1115	amino acid carrier protein
SMON_RS00970	COG3711	transcriptional antiterminator
SMON_RS00970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS00980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SMON_RS00985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SMON_RS00995	COG2723	6-phospho-beta-galactosidase activity
SMON_RS01015	COG4120	Belongs to the binding-protein-dependent transport system permease family
SMON_RS01040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SMON_RS01050	COG0052	Belongs to the universal ribosomal protein uS2 family
SMON_RS01055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SMON_RS01060	COG0528	UMP kinase activity
SMON_RS01065	COG0233	cytoplasmic translational termination
SMON_RS01070	COG1077	Cell shape determining protein MreB Mrl
SMON_RS01095	COG0803	Belongs to the bacterial solute-binding protein 9 family
SMON_RS01100	COG1121	(ABC) transporter
SMON_RS01105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SMON_RS01110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SMON_RS01175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SMON_RS01185	COG0525	valine-tRNA ligase activity
SMON_RS01200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SMON_RS01245	COG1459	type II secretion system
SMON_RS01285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SMON_RS01285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SMON_RS01295	COG1269	ATP hydrolysis coupled proton transport
SMON_RS01300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SMON_RS01305	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
SMON_RS01315	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SMON_RS01330	COG1394	ATPase activity, coupled to movement of substances
SMON_RS01335	COG3842	ATPase activity
SMON_RS01345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS01350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SMON_RS01370	COG1263	PTS System
SMON_RS01370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMON_RS01370	COG2190	(PTS) system
SMON_RS01380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SMON_RS01385	COG2003	Belongs to the UPF0758 family
SMON_RS01390	COG1774	PSP1 C-terminal conserved region
SMON_RS01405	COG0237	dephospho-CoA kinase activity
SMON_RS01410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SMON_RS01415	COG1704	LemA family
SMON_RS01440	COG3842	ATPase activity
SMON_RS01450	COG1840	ABC-type Fe3 transport system, periplasmic component
SMON_RS01455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SMON_RS01460	COG2011	ABC-type metal ion transport system permease component
SMON_RS01465	COG1464	Belongs to the NlpA lipoprotein family
SMON_RS01470	COG3210	domain, Protein
SMON_RS01485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SMON_RS01490	COG1494	fructose-1,6-bisphosphatase
SMON_RS01495	COG0681	Belongs to the peptidase S26 family
SMON_RS01505	COG1543	Belongs to the glycosyl hydrolase 57 family
SMON_RS01510	COG1104	cysteine desulfurase activity
SMON_RS01520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SMON_RS01555	COG2333	competence protein COMEC
SMON_RS01555	COG0658	competence protein
SMON_RS01565	COG1121	(ABC) transporter
SMON_RS01590	COG1799	cell septum assembly
SMON_RS01595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SMON_RS01600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SMON_RS01605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS01605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS01605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS01610	COG0572	uridine kinase
SMON_RS01615	COG1940	carbohydrate kinase activity
SMON_RS01620	COG1879	ABC-type sugar transport system periplasmic component
SMON_RS01625	COG1129	ABC transporter
SMON_RS01630	COG4211	Belongs to the binding-protein-dependent transport system permease family
SMON_RS01635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SMON_RS01645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SMON_RS01650	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SMON_RS01660	COG0442	prolyl-tRNA aminoacylation
SMON_RS01675	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SMON_RS01685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SMON_RS01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SMON_RS01695	COG2176	DNA-directed DNA polymerase activity
SMON_RS01700	COG0018	arginyl-trna synthetase
SMON_RS01715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SMON_RS01730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SMON_RS01735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SMON_RS01740	COG0202	RNA polymerase activity
SMON_RS01745	COG0203	ribosomal protein L17
SMON_RS01770	COG4977	sequence-specific DNA binding
SMON_RS01775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SMON_RS01780	COG0495	leucyl-tRNA aminoacylation
SMON_RS01790	COG1132	(ABC) transporter
SMON_RS01795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SMON_RS01800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SMON_RS01805	COG0497	DNA recombination
SMON_RS01810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SMON_RS01815	COG3119	arylsulfatase activity
SMON_RS01820	COG4974	Belongs to the 'phage' integrase family
SMON_RS01835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SMON_RS01850	COG1131	(ABC) transporter
SMON_RS01865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SMON_RS01870	COG0154	amidase activity
SMON_RS01875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SMON_RS01880	COG0768	penicillin binding
SMON_RS01885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SMON_RS01895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SMON_RS01900	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SMON_RS01915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SMON_RS01945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SMON_RS01950	COG1362	aminopeptidase activity
SMON_RS01955	COG3842	ATPase activity
SMON_RS01960	COG1176	ABC-type spermidine putrescine transport system, permease component I
SMON_RS01965	COG1177	transmembrane transport
SMON_RS01990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SMON_RS01995	COG0670	Belongs to the BI1 family
SMON_RS02015	COG4804	nuclease activity
SMON_RS02020	COG1185	polyribonucleotide nucleotidyltransferase activity
SMON_RS02025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SMON_RS02045	COG1686	Belongs to the peptidase S11 family
SMON_RS02050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SMON_RS02055	COG0180	Tryptophanyl-tRNA synthetase
SMON_RS02090	COG0205	6-phosphofructokinase activity
SMON_RS02100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SMON_RS02105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SMON_RS02115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SMON_RS02120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SMON_RS02125	COG1609	Transcriptional regulator
SMON_RS02135	COG1523	belongs to the glycosyl hydrolase 13 family
SMON_RS02160	COG1131	(ABC) transporter
SMON_RS02175	COG1175	transmembrane transport
SMON_RS02180	COG3833	ABC-type maltose transport systems, permease component
SMON_RS02185	COG3842	ATPase activity
SMON_RS02215	COG0017	Asparaginyl-tRNA synthetase
SMON_RS02230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SMON_RS02245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SMON_RS02260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SMON_RS02265	COG0668	transmembrane transport
SMON_RS02270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SMON_RS02410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SMON_RS02415	COG2252	PERMEase
SMON_RS02420	COG0583	DNA-binding transcription factor activity
SMON_RS02425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SMON_RS02435	COG1116	anion transmembrane transporter activity
SMON_RS02460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SMON_RS02465	COG0222	ribosome binding
SMON_RS02470	COG0085	RNA polymerase activity
SMON_RS02475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SMON_RS02480	COG0194	GDP metabolic process
SMON_RS02485	COG1758	RNA polymerase activity
SMON_RS02490	COG0358	DNA primase activity
SMON_RS02495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SMON_RS02510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SMON_RS02515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SMON_RS02520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SMON_RS02530	COG1074	ATP-dependent DNA helicase activity
SMON_RS02535	COG0210	DNA helicase
SMON_RS02540	COG0786	glutamate:sodium symporter activity
SMON_RS02545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SMON_RS02555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SMON_RS02560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SMON_RS02575	COG0322	excinuclease ABC activity
SMON_RS02580	COG3845	ABC transporter
SMON_RS02585	COG4603	Belongs to the binding-protein-dependent transport system permease family
SMON_RS02590	COG1079	Belongs to the binding-protein-dependent transport system permease family
SMON_RS02595	COG1744	ABC transporter substrate-binding protein PnrA-like
SMON_RS02600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SMON_RS02605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SMON_RS02610	COG0813	purine-nucleoside phosphorylase activity
SMON_RS02615	COG0295	cytidine deaminase activity
SMON_RS02625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SMON_RS02640	COG2195	Cleaves the N-terminal amino acid of tripeptides
SMON_RS02655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SMON_RS02670	COG0250	Participates in transcription elongation, termination and antitermination
SMON_RS02675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SMON_RS02680	COG0081	regulation of translation
SMON_RS02695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SMON_RS02700	COG0254	rRNA binding
SMON_RS02705	COG0268	Binds directly to 16S ribosomal RNA
SMON_RS02710	COG1199	ATP-dependent helicase activity
SMON_RS02715	COG1480	7TM receptor with intracellular HD hydrolase
SMON_RS02720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SMON_RS02725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SMON_RS02730	COG1227	inorganic diphosphatase activity
SMON_RS02735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SMON_RS02760	COG0737	Belongs to the 5'-nucleotidase family
SMON_RS02770	COG1780	Probably involved in ribonucleotide reductase function
SMON_RS02775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SMON_RS02780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SMON_RS02815	COG0436	Aminotransferase
SMON_RS02830	COG4145	pantothenate transmembrane transporter activity
SMON_RS02845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SMON_RS02865	COG0698	ribose 5-phosphate isomerase
SMON_RS02870	COG0537	adenosine 5'-monophosphoramidase activity
SMON_RS02875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SMON_RS02880	COG1064	alcohol dehydrogenase
SMON_RS02920	COG0084	hydrolase, TatD family'
SMON_RS02925	COG0736	holo-[acyl-carrier-protein] synthase activity
SMON_RS02935	COG1473	amidohydrolase
SMON_RS02940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SMON_RS02955	COG1125	glycine betaine transport
SMON_RS02955	COG0517	IMP dehydrogenase activity
SMON_RS02960	COG1732	Glycine betaine
SMON_RS02965	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SMON_RS02970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SMON_RS02975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SMON_RS03015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SMON_RS03020	COG2226	methyltransferase
SMON_RS03030	COG0756	dUTP diphosphatase activity
SMON_RS03035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SMON_RS03040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SMON_RS03045	COG4589	Belongs to the CDS family
SMON_RS03065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SMON_RS03070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SMON_RS03075	COG0765	amino acid transport
SMON_RS03100	COG1519	Transferase
SMON_RS03100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SMON_RS03145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SMON_RS03150	COG0154	amidase activity
SMON_RS03155	COG4946	Tricorn protease homolog
SMON_RS03155	COG0823	Involved in the tonB-independent uptake of proteins
SMON_RS03155	COG1506	peptidase
SMON_RS03165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SMON_RS03170	COG2890	protein-(glutamine-N5) methyltransferase activity
SMON_RS03175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SMON_RS03180	COG0742	ribosomal rna small subunit methyltransferase
SMON_RS03190	COG0142	geranyltranstransferase activity
SMON_RS03195	COG1496	oxidoreductase activity
SMON_RS03205	COG0653	protein targeting
SMON_RS03215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SMON_RS03220	COG2011	ABC-type metal ion transport system permease component
SMON_RS03225	COG1464	Belongs to the NlpA lipoprotein family
SMON_RS03230	COG0628	permease
SMON_RS03240	COG2385	sporulation resulting in formation of a cellular spore
SMON_RS03245	COG0037	tRNA processing
SMON_RS03250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SMON_RS03255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SMON_RS03260	COG1193	negative regulation of DNA recombination
SMON_RS03265	COG0215	cysteine-tRNA ligase activity
SMON_RS03270	COG1077	Cell shape determining protein MreB Mrl
SMON_RS03275	COG0470	DNA polymerase III
SMON_RS03280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SMON_RS03285	COG0632	four-way junction helicase activity
SMON_RS03300	COG0436	Aminotransferase
SMON_RS03305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SMON_RS03400	COG4581	dead DEAH box helicase
SMON_RS03415	COG3843	relaxase mobilization nuclease domain protein
SMON_RS03455	COG3069	C4-dicarboxylate transmembrane transporter activity
SMON_RS03465	COG1132	(ABC) transporter
SMON_RS03470	COG1132	(ABC) transporter
SMON_RS03485	COG1129	ABC transporter
SMON_RS03545	COG1217	gtp-binding protein TYPA
SMON_RS03565	COG1136	(ABC) transporter
SMON_RS03565	COG0577	efflux transmembrane transporter activity
SMON_RS03570	COG0577	efflux transmembrane transporter activity
SMON_RS03580	COG0826	peptidase U32
SMON_RS03590	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SMON_RS03595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SMON_RS03605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SMON_RS03620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SMON_RS03625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SMON_RS03635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SMON_RS03640	COG0557	exoribonuclease II activity
SMON_RS03645	COG1713	HD superfamily hydrolase involved in NAD metabolism
SMON_RS03665	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
SMON_RS03670	COG2391	methyltransferase activity
SMON_RS03700	COG0488	(ABC) transporter
SMON_RS03710	COG2239	Acts as a magnesium transporter
SMON_RS03730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SMON_RS03740	COG0037	tRNA processing
SMON_RS03750	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SMON_RS03750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SMON_RS03765	COG5002	protein histidine kinase activity
SMON_RS03770	COG0745	RESPONSE REGULATOR receiver
SMON_RS03775	COG0826	peptidase U32
SMON_RS03780	COG0305	Participates in initiation and elongation during chromosome replication
SMON_RS03785	COG0359	binds to the 23S rRNA
SMON_RS03790	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SMON_RS03800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SMON_RS03805	COG1187	pseudouridine synthase activity
SMON_RS03830	COG1435	thymidine kinase activity
SMON_RS03835	COG0791	NLP P60 protein
SMON_RS03845	COG2860	membrane
SMON_RS03855	COG0481	GTPase activity
SMON_RS03875	COG0424	maF-like protein
SMON_RS03885	COG0728	peptidoglycan biosynthetic process
SMON_RS03890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SMON_RS03895	COG0196	riboflavin kinase activity
SMON_RS03900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SMON_RS03905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SMON_RS03910	COG0740	serine-type endopeptidase activity
SMON_RS03915	COG0544	peptidyl-prolyl cis-trans isomerase activity
SMON_RS03920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SMON_RS03920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SMON_RS03925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SMON_RS03930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SMON_RS03940	COG0195	Participates in both transcription termination and antitermination
SMON_RS03945	COG0779	Required for maturation of 30S ribosomal subunits
SMON_RS03950	COG0217	transcriptional regulatory protein
SMON_RS03960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SMON_RS03965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SMON_RS03970	COG0571	ribonuclease III activity
SMON_RS03980	COG1011	Hydrolase
SMON_RS03995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SMON_RS04000	COG2116	formate transmembrane transporter activity
SMON_RS04005	COG0708	Exodeoxyribonuclease III
SMON_RS04015	COG0275	rRNA processing
SMON_RS04025	COG0058	SHG alpha-glucan phosphorylase activity
SMON_RS04050	COG0149	triose-phosphate isomerase activity
SMON_RS04065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SMON_RS04070	COG1253	flavin adenine dinucleotide binding
SMON_RS04075	COG1940	carbohydrate kinase activity
SMON_RS04080	COG1012	belongs to the aldehyde dehydrogenase family
SMON_RS04130	COG3118	belongs to the thioredoxin family
SMON_RS04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SMON_RS04150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SMON_RS04165	COG1295	ribonuclease BN
SMON_RS04170	COG0301	tRNA thio-modification
SMON_RS04175	COG0343	queuine tRNA-ribosyltransferase activity
SMON_RS04180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SMON_RS04200	COG0438	transferase activity, transferring glycosyl groups
SMON_RS04210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SMON_RS04220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SMON_RS04225	COG1136	(ABC) transporter
SMON_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS04250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS04250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS04255	COG1381	Involved in DNA repair and RecF pathway recombination
SMON_RS04265	COG1792	Involved in formation and maintenance of cell shape
SMON_RS04305	COG0336	Belongs to the RNA methyltransferase TrmD family
SMON_RS04310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SMON_RS04325	COG4752	Belongs to the RNA methyltransferase TrmD family
SMON_RS04330	COG0617	tRNA 3'-terminal CCA addition
SMON_RS04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SMON_RS04335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SMON_RS04400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SMON_RS04425	COG0791	NLP P60 protein
SMON_RS04470	COG3309	Virulence-associated protein D
SMON_RS04490	COG3451	type IV secretory pathway VirB4
SMON_RS04525	COG4962	Type ii secretion system protein e
SMON_RS04615	COG4974	Belongs to the 'phage' integrase family
SMON_RS04620	COG0335	large ribosomal subunit rRNA binding
SMON_RS04640	COG1196	nuclear chromosome segregation
SMON_RS04650	COG1570	exodeoxyribonuclease VII activity
SMON_RS04655	COG1393	Belongs to the ArsC family
SMON_RS04660	COG0556	nucleotide-excision repair
SMON_RS04665	COG1649	PFAM Uncharacterised BCR, COG1649
SMON_RS04690	COG0601	transmembrane transport
SMON_RS04695	COG1278	Cold shock
SMON_RS04700	COG0564	pseudouridine synthase activity
SMON_RS04705	COG0772	Belongs to the SEDS family
SMON_RS04710	COG0612	Peptidase, M16
SMON_RS04720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SMON_RS04725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SMON_RS04730	COG1692	metallophosphoesterase
SMON_RS04735	COG1418	mRNA catabolic process
SMON_RS04755	COG0006	proline dipeptidase activity
SMON_RS04760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SMON_RS04765	COG0601	transmembrane transport
SMON_RS04770	COG4608	Belongs to the ABC transporter superfamily
SMON_RS04790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SMON_RS04795	COG0516	GMP reductase activity
SMON_RS04795	COG0517	IMP dehydrogenase activity
SMON_RS04800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SMON_RS04805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SMON_RS04810	COG0445	tRNA wobble uridine modification
SMON_RS04820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SMON_RS04825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SMON_RS04840	COG2813	Specifically methylates the guanine in position
SMON_RS04870	COG0616	signal peptide processing
SMON_RS04890	COG0148	phosphopyruvate hydratase activity
SMON_RS04905	COG3693	PFAM glycoside hydrolase, family 10
SMON_RS04905	COG2382	esterase
SMON_RS04905	COG3507	Belongs to the glycosyl hydrolase 43 family
SMON_RS04915	COG1737	Transcriptional regulator
SMON_RS04925	COG3842	ATPase activity
SMON_RS04935	COG1840	ABC-type Fe3 transport system, periplasmic component
SMON_RS04960	COG2233	PERMEase
SMON_RS04975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SMON_RS04995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMON_RS04995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMON_RS05010	COG0750	zinc metalloprotease
SMON_RS05020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SMON_RS05025	COG0534	Mate efflux family protein
SMON_RS05035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SMON_RS05040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SMON_RS05045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SMON_RS05050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SMON_RS05055	COG2342	PFAM TM1410 hypothetical-related protein
SMON_RS05075	COG0446	pyridine nucleotide-disulphide oxidoreductase
SMON_RS05085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SMON_RS05090	COG0300	oxidoreductase activity
SMON_RS05100	COG0641	radical SAM
SMON_RS05120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SMON_RS05130	COG0791	NLP P60 protein
SMON_RS05135	COG1490	D-aminoacyl-tRNA deacylase activity
SMON_RS05155	COG0730	response to heat
SMON_RS05160	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SMON_RS05165	COG2081	HI0933 family
SMON_RS05175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SMON_RS05185	COG2171	N-acyltransferase activity
SMON_RS05195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SMON_RS05210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SMON_RS05245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SMON_RS05260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SMON_RS05265	COG0863	Belongs to the N(4) N(6)-methyltransferase family
SMON_RS05280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SMON_RS05295	COG0395	ABC-type sugar transport system, permease component
SMON_RS05310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SMON_RS05320	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SMON_RS05325	COG1737	Transcriptional regulator
SMON_RS05335	COG1454	alcohol dehydrogenase
SMON_RS05335	COG1012	belongs to the aldehyde dehydrogenase family
SMON_RS05340	COG0251	oxidation-reduction process
SMON_RS05345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SMON_RS05360	COG2195	Cleaves the N-terminal amino acid of tripeptides
SMON_RS05365	COG1882	Formate acetyltransferase
SMON_RS05370	COG0588	phosphoglycerate mutase activity
SMON_RS05380	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SMON_RS05395	COG3210	domain, Protein
SMON_RS05395	COG3468	outer membrane autotransporter barrel domain protein
SMON_RS05415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SMON_RS05420	COG0124	histidyl-tRNA synthetase
SMON_RS05425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SMON_RS05430	COG0822	iron-sulfur transferase activity
SMON_RS05460	COG1160	GTP binding
SMON_RS05465	COG1739	Uncharacterized protein family UPF0029
SMON_RS05475	COG1181	Belongs to the D-alanine--D-alanine ligase family
SMON_RS05485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SMON_RS05505	COG0357	Ribosomal RNA small subunit methyltransferase G
SMON_RS05510	COG0768	penicillin binding
SMON_RS05515	COG0799	negative regulation of ribosome biogenesis
SMON_RS05530	COG2255	four-way junction helicase activity
SMON_RS05540	COG0751	glycine-tRNA ligase activity
SMON_RS05545	COG0752	glycyl-tRNA synthetase alpha subunit
SMON_RS05550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SMON_RS05555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SMON_RS05560	COG2183	response to ionizing radiation
SMON_RS05575	COG0564	pseudouridine synthase activity
SMON_RS05585	COG0546	phosphoglycolate phosphatase activity
SMON_RS05590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SMON_RS05590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SMON_RS05600	COG1132	(ABC) transporter
SMON_RS05605	COG1132	(ABC) transporter
SMON_RS05615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SMON_RS05660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SMON_RS05665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SMON_RS05670	COG2137	regulation of response to DNA damage stimulus
SMON_RS05675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SMON_RS05695	COG1164	Oligoendopeptidase f
SMON_RS05710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SMON_RS05715	COG0450	alkyl hydroperoxide reductase
SMON_RS05730	COG0445	tRNA wobble uridine modification
SMON_RS05735	COG5522	Integral membrane protein (intg_mem_TP0381)
SMON_RS05785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SMON_RS05790	COG0719	Fe-S assembly protein
SMON_RS05800	COG0396	ATPase activity
SMON_RS05805	COG0697	spore germination
SMON_RS05815	COG1131	(ABC) transporter
SMON_RS05820	COG3958	Transketolase
SMON_RS05825	COG3959	Transketolase, thiamine diphosphate binding domain
SMON_RS05860	COG3064	Membrane
SMON_RS05860	COG3210	domain, Protein
SMON_RS05860	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
SMON_RS05865	COG3700	Belongs to the class B bacterial acid phosphatase family
SMON_RS05870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SMON_RS05895	COG0791	NLP P60 protein
SMON_RS05905	COG2885	chlorophyll binding
SMON_RS05960	COG3451	type IV secretory pathway VirB4
SMON_RS05990	COG4962	Type ii secretion system protein e
SMON_RS06055	COG1570	exodeoxyribonuclease VII activity
SMON_RS06135	COG2815	serine threonine protein kinase
SMON_RS06135	COG0515	serine threonine protein kinase
SMON_RS06140	COG1162	GTPase activity
SMON_RS06145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SMON_RS06155	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SMON_RS06160	COG0363	glucosamine-6-phosphate deaminase activity
SMON_RS06180	COG1956	GAF domain-containing protein
SMON_RS06185	COG0095	Lipoate-protein ligase
SMON_RS06190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SMON_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SMON_RS06200	COG0508	dehydrogenase complex catalyzes the overall conversion of
SMON_RS06205	COG0022	dehydrogenase e1 component
SMON_RS06210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SMON_RS06230	COG1132	(ABC) transporter
SMON_RS06235	COG1132	(ABC) transporter
SMON_RS06245	COG0006	proline dipeptidase activity
SMON_RS06250	COG1266	CAAX protease self-immunity
SMON_RS06275	COG0778	Nitroreductase
SMON_RS06290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SMON_RS06290	COG1328	CTP reductase activity
SMON_RS06340	COG2217	Heavy metal translocating P-type atpase
SMON_RS06355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SMON_RS06360	COG0803	Belongs to the bacterial solute-binding protein 9 family
SMON_RS06385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMON_RS06385	COG0072	phenylalanine-tRNA ligase activity
SMON_RS06390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SMON_RS06410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SMON_RS06415	COG0187	DNA topoisomerase II activity
SMON_RS06425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SMON_RS06445	COG0200	Binds to the 23S rRNA
SMON_RS06450	COG1841	ribosomal large subunit assembly
SMON_RS06455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SMON_RS06460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SMON_RS06465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SMON_RS06470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SMON_RS06475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SMON_RS06480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SMON_RS06490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SMON_RS06495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SMON_RS06500	COG0255	Belongs to the universal ribosomal protein uL29 family
SMON_RS06505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SMON_RS06510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SMON_RS06515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SMON_RS06520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SMON_RS06525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SMON_RS06540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SMON_RS06555	COG0656	L-ascorbic acid biosynthetic process
SMON_RS06560	COG3579	cysteine-type endopeptidase activity
SMON_RS06570	COG3425	synthase
SMON_RS06590	COG0166	Belongs to the GPI family
SMON_RS06620	COG3716	PTS system mannose fructose sorbose family IID component
SMON_RS06625	COG3715	PTS system
SMON_RS06645	COG0640	Transcriptional regulator
SMON_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
SMON_RS06655	COG1312	Catalyzes the dehydration of D-mannonate
SMON_RS06660	COG1904	glucuronate isomerase
SMON_RS06670	COG2211	Major facilitator Superfamily
SMON_RS06675	COG3250	beta-galactosidase activity
SMON_RS06700	COG2826	transposase and inactivated derivatives, IS30 family
SMON_RS06730	COG0235	Class ii aldolase
SMON_RS06735	COG3623	hexulose-6-phosphate isomerase
SMON_RS06740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS06750	COG3037	sugar-specific permease SgaT UlaA
SMON_RS06760	COG1966	Carbon starvation protein
SMON_RS06765	COG1966	Carbon starvation protein
SMON_RS06790	COG1482	cell wall glycoprotein biosynthetic process
SMON_RS06800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SMON_RS06870	COG0563	adenylate kinase activity
SMON_RS06885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SMON_RS06895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SMON_RS06905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SMON_RS06915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMON_RS06915	COG1263	PTS System
SMON_RS06915	COG2190	(PTS) system
SMON_RS06920	COG3711	transcriptional antiterminator
SMON_RS06930	COG0484	heat shock protein binding
SMON_RS06940	COG0443	Heat shock 70 kDa protein
SMON_RS06945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SMON_RS06950	COG1420	regulation of RNA biosynthetic process
SMON_RS06955	COG0542	response to heat
SMON_RS06980	COG1187	pseudouridine synthase activity
SMON_RS06985	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SMON_RS06990	COG1077	Cell shape determining protein MreB Mrl
SMON_RS07005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SMON_RS07015	COG0657	acetylesterase activity
SMON_RS07020	COG0657	acetylesterase activity
SMON_RS07025	COG4797	methyltransferase
SMON_RS07025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SMON_RS07030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SMON_RS07045	COG3958	Transketolase
SMON_RS07050	COG3959	Transketolase, thiamine diphosphate binding domain
SMON_RS07055	COG2211	Major facilitator Superfamily
SMON_RS07060	COG2197	response regulator
SMON_RS07075	COG1136	(ABC) transporter
SMON_RS07090	COG1323	Belongs to the UPF0348 family
SMON_RS07095	COG1902	pentaerythritol trinitrate reductase activity
SMON_RS07120	COG1132	(ABC) transporter
SMON_RS07130	COG3775	system Galactitol-specific IIC component
SMON_RS07145	COG0657	acetylesterase activity
SMON_RS07160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SMON_RS07165	COG1968	undecaprenyl-diphosphatase activity
SMON_RS07180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SMON_RS07230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SMON_RS07230	COG0519	Catalyzes the synthesis of GMP from XMP
SMON_RS07240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SMON_RS07245	COG0785	Cytochrome C biogenesis protein
SMON_RS07255	COG1051	belongs to the nudix hydrolase family
SMON_RS07265	COG0539	negative regulation of cytoplasmic translation
SMON_RS07265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SMON_RS07270	COG1461	Dihydroxyacetone kinase
SMON_RS07275	COG0564	pseudouridine synthase activity
SMON_RS07290	COG0616	signal peptide processing
SMON_RS07330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SMON_RS07335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SMON_RS07340	COG0009	L-threonylcarbamoyladenylate synthase
SMON_RS07350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SMON_RS07360	COG0101	tRNA pseudouridine synthase activity
SMON_RS07370	COG0561	phosphatase activity
SMON_RS07375	COG0228	four-way junction DNA binding
SMON_RS07380	COG1022	Amp-dependent synthetase and ligase
SMON_RS07390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SMON_RS07395	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SMON_RS07445	COG1114	Component of the transport system for branched-chain amino acids
SMON_RS07460	COG0601	transmembrane transport
SMON_RS07465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SMON_RS07470	COG1126	abc transporter atp-binding protein
SMON_RS07475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SMON_RS07485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SMON_RS07500	COG0587	DNA-directed DNA polymerase activity
SMON_RS07520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SMON_RS07530	COG0360	Binds together with S18 to 16S ribosomal RNA
SMON_RS07575	COG0745	RESPONSE REGULATOR receiver
SMON_RS07580	COG0745	RESPONSE REGULATOR receiver
SMON_RS07580	COG2205	protein histidine kinase activity
SMON_RS07580	COG3292	Two component regulator propeller
SMON_RS07595	COG2848	UPF0210 protein
SMON_RS07605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SMON_RS07615	COG0193	aminoacyl-tRNA hydrolase activity
SMON_RS07690	COG2059	Chromate
SMON_RS07720	COG3172	ATPase kinase involved in NAD metabolism
SMON_RS07745	COG0860	N-Acetylmuramoyl-L-alanine amidase
SMON_RS07760	COG2885	chlorophyll binding
SMON_RS07815	COG0745	RESPONSE REGULATOR receiver
SMON_RS07820	COG4409	exo-alpha-(2->6)-sialidase activity