locus-tag	class	description
SAG0002	COG0592	DNA-directed DNA polymerase activity
SAG0003	COG1597	lipid kinase activity
SAG0006	COG0012	GTP binding
SAG0008	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SAG0010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAG0016	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAG0019	COG0436	Aminotransferase
SAG0022	COG0416	fatty acid biosynthetic process
SAG0023	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAG0025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAG0028	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SAG0030	COG0138	bifunctional purine biosynthesis protein purh
SAG0033	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SAG0035	COG1175	transmembrane transport
SAG0036	COG0395	ABC-type sugar transport system, permease component
SAG0039	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAG0041	COG3458	cephalosporin-C deacetylase activity
SAG0044	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAG0047	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAG0050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAG0052	COG2755	lipolytic protein G-D-S-L family
SAG0052	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAG0053	COG1454	alcohol dehydrogenase
SAG0053	COG1012	belongs to the aldehyde dehydrogenase family
SAG0054	COG1064	alcohol dehydrogenase
SAG0056	COG0534	Mate efflux family protein
SAG0078	COG0201	protein transport
SAG0079	COG0563	adenylate kinase activity
SAG0082	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAG0084	COG0202	RNA polymerase activity
SAG0094	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAG0097	COG0443	Heat shock 70 kDa protein
SAG0099	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAG0101	COG0351	phosphomethylpyrimidine kinase
SAG0102	COG4720	Psort location CytoplasmicMembrane, score
SAG0104	COG0668	transmembrane transport
SAG0109	COG0756	dUTP diphosphatase activity
SAG0112	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAG0114	COG1879	ABC-type sugar transport system periplasmic component
SAG0115	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAG0118	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAG0119	COG1609	Transcriptional regulator
SAG0121	COG0577	efflux transmembrane transporter activity
SAG0122	COG1136	(ABC) transporter
SAG0123	COG0745	RESPONSE REGULATOR receiver
SAG0124	COG5002	protein histidine kinase activity
SAG0127	COG0191	fructose-bisphosphate aldolase activity
SAG0131	COG1461	Dihydroxyacetone kinase
SAG0135	COG1126	abc transporter atp-binding protein
SAG0136	COG0765	amino acid transport
SAG0140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAG0142	COG0719	Fe-S assembly protein
SAG0143	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAG0145	COG0719	Fe-S assembly protein
SAG0146	COG1686	Belongs to the peptidase S11 family
SAG0147	COG1686	Belongs to the peptidase S11 family
SAG0148	COG4166	transmembrane transport
SAG0149	COG0601	transmembrane transport
SAG0150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAG0151	COG0444	Belongs to the ABC transporter superfamily
SAG0152	COG4608	Belongs to the ABC transporter superfamily
SAG0155	COG1121	(ABC) transporter
SAG0156	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAG0159	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAG0159	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAG0163	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAG0164	COG1459	type II secretion system
SAG0173	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAG0174	COG1363	Peptidase, m42
SAG0177	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAG0178	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAG0181	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAG0185	COG1346	cytolysis
SAG0188	COG0601	transmembrane transport
SAG0190	COG1122	ATPase activity
SAG0192	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG0192	COG1263	PTS System
SAG0193	COG0366	Alpha amylase catalytic
SAG0194	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAG0195	COG5433	transposase activity
SAG0199	COG3959	Transketolase, thiamine diphosphate binding domain
SAG0200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SAG0201	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAG0205	COG1045	serine acetyltransferase
SAG0208	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAG0214	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAG0217	COG4974	Belongs to the 'phage' integrase family
SAG0239	COG1396	sequence-specific DNA binding
SAG0240	COG2814	Major facilitator Superfamily
SAG0242	COG1732	Glycine betaine
SAG0253	COG0519	Catalyzes the synthesis of GMP from XMP
SAG0264	COG1695	Transcriptional regulator
SAG0267	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAG0275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAG0276	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAG0280	COG1131	(ABC) transporter
SAG0282	COG2190	(PTS) system
SAG0282	COG1263	PTS System
SAG0282	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG0283	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAG0287	COG0768	penicillin binding
SAG0289	COG0513	Belongs to the DEAD box helicase family
SAG0292	COG1126	abc transporter atp-binding protein
SAG0294	COG0492	ferredoxin-NADP+ reductase activity
SAG0295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAG0297	COG3579	cysteine-type endopeptidase activity
SAG0298	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAG0303	COG0116	Belongs to the methyltransferase superfamily
SAG0305	COG1854	S-ribosylhomocysteine lyase activity
SAG0306	COG1418	mRNA catabolic process
SAG0306	COG4372	Transposase
SAG0308	COG1131	(ABC) transporter
SAG0310	COG4585	Histidine kinase
SAG0313	COG0194	GDP metabolic process
SAG0315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAG0316	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAG0317	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAG0317	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAG0319	COG2815	serine threonine protein kinase
SAG0319	COG0515	serine threonine protein kinase
SAG0321	COG4585	Histidine kinase
SAG0322	COG2197	response regulator
SAG0324	COG1098	S1 RNA binding domain
SAG0325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAG0326	COG1349	DNA-binding transcription factor activity
SAG0328	COG1447	Phosphotransferase system cellobiose-specific component IIA
SAG0330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAG0331	COG1882	Formate acetyltransferase
SAG0335	COG1739	Uncharacterized protein family UPF0029
SAG0336	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAG0337	COG1040	competence protein
SAG0339	COG0527	aspartate kinase activity
SAG0340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAG0342	COG1024	Enoyl-CoA hydratase
SAG0344	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAG0346	COG2070	2-Nitropropane dioxygenase
SAG0347	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SAG0348	COG1028	Short-chain dehydrogenase reductase Sdr
SAG0349	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAG0352	COG0439	Biotin carboxylase
SAG0356	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAG0359	COG3716	PTS system mannose fructose sorbose family IID component
SAG0360	COG3715	PTS system
SAG0362	COG0561	phosphatase activity
SAG0365	COG2252	PERMEase
SAG0366	COG0802	atpase or kinase
SAG0368	COG1316	TRANSCRIPTIONal
SAG0370	COG0537	adenosine 5'-monophosphoramidase activity
SAG0373	COG1131	(ABC) transporter
SAG0374	COG4473	ABC transporter
SAG0376	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAG0378	COG0195	Participates in both transcription termination and antitermination
SAG0379	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAG0382	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAG0387	COG2860	membrane
SAG0389	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAG0389	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAG0390	COG1832	CoA-binding protein
SAG0394	COG5002	protein histidine kinase activity
SAG0398	COG1268	BioY protein
SAG0399	COG1234	tRNA 3'-trailer cleavage
SAG0402	COG0166	Belongs to the GPI family
SAG0403	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAG0404	COG0457	Tetratricopeptide repeat
SAG0404	COG0705	Rhomboid family
SAG0405	COG1744	ABC transporter substrate-binding protein PnrA-like
SAG0406	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAG0415	COG2153	protein acetylation
SAG0417	COG1216	Glycosyl transferase, family 2
SAG0417	COG1442	glycosyl transferase family 8
SAG0425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAG0427	COG0789	Transcriptional regulator
SAG0428	COG1063	alcohol dehydrogenase
SAG0429	COG0656	L-ascorbic acid biosynthetic process
SAG0434	COG3328	transposase activity
SAG0438	COG0582	viral genome integration into host DNA
SAG0443	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAG0446	COG0673	inositol 2-dehydrogenase activity
SAG0448	COG3328	transposase activity
SAG0449	COG2315	Protein conserved in bacteria
SAG0452	COG0742	ribosomal rna small subunit methyltransferase
SAG0455	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAG0457	COG4470	Protein conserved in bacteria
SAG0460	COG1132	(ABC) transporter
SAG0461	COG1132	(ABC) transporter
SAG0462	COG0512	Glutamine amidotransferase of anthranilate synthase
SAG0463	COG1268	BioY protein
SAG0466	COG0183	Belongs to the thiolase family
SAG0468	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAG0471	COG1940	carbohydrate kinase activity
SAG0472	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAG0473	COG1217	gtp-binding protein TYPA
SAG0480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAG0482	COG0762	integral membrane protein
SAG0483	COG2302	S4 RNA-binding domain
SAG0484	COG3599	regulation of cell shape
SAG0487	COG0494	nUDIX hydrolase
SAG0488	COG0542	response to heat
SAG0490	COG4703	Protein of unknown function (DUF1797)
SAG0491	COG0765	amino acid transport
SAG0492	COG1126	abc transporter atp-binding protein
SAG0493	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAG0495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAG0497	COG1722	exodeoxyribonuclease VII activity
SAG0499	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SAG0500	COG1438	arginine binding
SAG0501	COG0497	DNA recombination
SAG0502	COG1307	EDD domain protein, DegV family
SAG0503	COG2755	lipolytic protein G-D-S-L family
SAG0512	COG1078	dGTPase activity
SAG0517	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAG0519	COG2884	Cell division ATP-binding protein ftsE
SAG0520	COG2177	Part of the ABC transporter FtsEX involved in
SAG0524	COG1199	ATP-dependent helicase activity
SAG0524	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAG0525	COG0436	Aminotransferase
SAG0526	COG0017	Asparaginyl-tRNA synthetase
SAG0531	COG1660	Displays ATPase and GTPase activities
SAG0536	COG0254	rRNA binding
SAG0537	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAG0538	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAG0539	COG0716	FMN binding
SAG0540	COG1605	Chorismate mutase
SAG0540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAG0541	COG0038	chloride channel
SAG0544	COG0335	large ribosomal subunit rRNA binding
SAG0545	COG0582	viral genome integration into host DNA
SAG0548	COG1396	sequence-specific DNA binding
SAG0555	COG3561	AntA/AntB antirepressor
SAG0567	COG3344	reverse transcriptase
SAG0614	COG1136	(ABC) transporter
SAG0617	COG5002	protein histidine kinase activity
SAG0621	COG0772	Belongs to the SEDS family
SAG0625	COG0560	Phosphoserine phosphatase
SAG0628	COG0148	phosphopyruvate hydratase activity
SAG0632	COG1316	TRANSCRIPTIONal
SAG0635	COG3700	Belongs to the class B bacterial acid phosphatase family
SAG0658	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAG0659	COG4555	ABC transporter
SAG0664	COG1028	Short-chain dehydrogenase reductase Sdr
SAG0665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAG0666	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAG0670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SAG0671	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAG0675	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SAG0675	COG3064	Membrane
SAG0684	COG1136	(ABC) transporter
SAG0687	COG0586	Pfam SNARE associated Golgi protein
SAG0688	COG4619	ABC transporter
SAG0689	COG0390	transport system, permease component
SAG0691	COG0583	DNA-binding transcription factor activity
SAG0693	COG5433	transposase activity
SAG0696	COG2211	Major facilitator Superfamily
SAG0698	COG3250	beta-galactosidase activity
SAG0699	COG2186	Transcriptional regulator
SAG0700	COG0800	Aldolase
SAG0703	COG1028	Short-chain dehydrogenase reductase Sdr
SAG0707	COG1609	Transcriptional regulator
SAG0710	COG0438	transferase activity, transferring glycosyl groups
SAG0715	COG0765	amino acid transport
SAG0716	COG0765	amino acid transport
SAG0717	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAG0718	COG1126	abc transporter atp-binding protein
SAG0719	COG0745	RESPONSE REGULATOR receiver
SAG0720	COG5002	protein histidine kinase activity
SAG0721	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAG0722	COG2832	Protein of unknown function (DUF454)
SAG0724	COG1196	nuclear chromosome segregation
SAG0725	COG0561	phosphatase activity
SAG0726	COG0561	phosphatase activity
SAG0727	COG0552	protein localization to endoplasmic reticulum
SAG0728	COG3689	TIGRFAM TIGR03943 family protein
SAG0729	COG0701	Predicted permease
SAG0732	COG2183	response to ionizing radiation
SAG0733	COG3091	SprT-like family
SAG0734	COG1983	PspC domain protein
SAG0742	COG0826	peptidase U32
SAG0743	COG4443	Transcriptional Coactivator p15 (PC4)
SAG0745	COG1914	H( )-stimulated, divalent metal cation uptake system
SAG0748	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAG0748	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAG0753	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAG0758	COG1164	Oligoendopeptidase f
SAG0760	COG5433	transposase activity
SAG0761	COG0772	Belongs to the SEDS family
SAG0765	COG0768	penicillin binding
SAG0768	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAG0769	COG2223	nitrite transmembrane transporter activity
SAG0774	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAG0775	COG2011	ABC-type metal ion transport system permease component
SAG0776	COG1464	Belongs to the NlpA lipoprotein family
SAG0777	COG0513	Belongs to the DEAD box helicase family
SAG0779	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAG0780	COG0204	Acyl-transferase
SAG0781	COG1596	polysaccharide export
SAG0781	COG1555	photosystem II stabilization
SAG0782	COG2333	competence protein COMEC
SAG0782	COG0658	competence protein
SAG0783	COG0561	phosphatase activity
SAG0784	COG1609	Transcriptional regulator
SAG0785	COG0657	acetylesterase activity
SAG0786	COG2226	methyltransferase
SAG0788	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAG0789	COG3711	transcriptional antiterminator
SAG0790	COG1263	PTS System
SAG0790	COG2190	(PTS) system
SAG0790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG0792	COG3835	regulator
SAG0793	COG1929	Belongs to the glycerate kinase type-1 family
SAG0794	COG2610	gluconate transmembrane transporter activity
SAG0796	COG1846	Transcriptional regulator
SAG0799	COG0363	glucosamine-6-phosphate deaminase activity
SAG0800	COG0435	Glutathione S-transferase
SAG0801	COG1187	pseudouridine synthase activity
SAG0806	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAG0807	COG4122	O-methyltransferase activity
SAG0809	COG4894	glucomannan catabolic process
SAG0812	COG1442	glycosyl transferase family 8
SAG0815	COG1476	TRANSCRIPTIONal
SAG0818	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAG0819	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAG0820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAG0823	COG1012	belongs to the aldehyde dehydrogenase family
SAG0824	COG0726	polysaccharide deacetylase
SAG0827	COG1956	GAF domain-containing protein
SAG0828	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAG0830	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SAG0830	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SAG0836	COG4721	ABC-type cobalt transport system, permease component
SAG0837	COG1122	ATPase activity
SAG0839	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAG0845	COG4109	DRTGG domain
SAG0846	COG0024	Methionine aminopeptidase
SAG0848	COG2246	polysaccharide biosynthetic process
SAG0849	COG4708	membrane
SAG0851	COG1597	lipid kinase activity
SAG0852	COG1523	belongs to the glycosyl hydrolase 13 family
SAG0872	COG2321	neutral zinc metallopeptidase
SAG0877	COG0488	(ABC) transporter
SAG0878	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAG0879	COG0022	dehydrogenase e1 component
SAG0879	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAG0880	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAG0882	COG0095	Lipoate-protein ligase
SAG0883	COG3442	glutamine amidotransferase
SAG0884	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAG0885	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAG0890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAG0892	COG0647	UMP catabolic process
SAG0894	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SAG0895	COG1518	maintenance of DNA repeat elements
SAG0896	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SAG0906	COG0481	GTPase activity
SAG0908	COG1418	mRNA catabolic process
SAG0909	COG0456	acetyltransferase
SAG0911	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAG0926	COG0791	NLP P60 protein
SAG0926	COG0741	lytic transglycosylase activity
SAG0932	COG2946	Replication initiation factor
SAG0933	COG1674	ftsk spoiiie
SAG0938	COG1725	Transcriptional regulator
SAG0940	COG0205	6-phosphofructokinase activity
SAG0941	COG0469	pyruvate kinase activity
SAG0945	COG5433	transposase activity
SAG0946	COG2824	Alkylphosphonate utilization operon protein PhnA
SAG0947	COG0765	amino acid transport
SAG0948	COG1126	abc transporter atp-binding protein
SAG0951	COG1072	(Pantothenic acid kinase))
SAG0952	COG2813	Specifically methylates the guanine in position
SAG0954	COG1744	ABC transporter substrate-binding protein PnrA-like
SAG0955	COG3845	ABC transporter
SAG0956	COG4603	Belongs to the binding-protein-dependent transport system permease family
SAG0957	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAG0961	COG3764	Sortase (surface protein transpeptidase)
SAG0962	COG0346	lactoylglutathione lyase activity
SAG0968	COG2188	Transcriptional regulator
SAG0971	COG1464	Belongs to the NlpA lipoprotein family
SAG0974	COG1136	(ABC) transporter
SAG0976	COG0745	RESPONSE REGULATOR receiver
SAG0977	COG5002	protein histidine kinase activity
SAG0978	COG4974	Belongs to the 'phage' integrase family
SAG0979	COG4166	transmembrane transport
SAG0982	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAG0983	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SAG0984	COG5002	protein histidine kinase activity
SAG0985	COG0745	RESPONSE REGULATOR receiver
SAG0987	COG0704	Plays a role in the regulation of phosphate uptake
SAG0988	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAG0989	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAG0990	COG0581	inorganic phosphate transmembrane transporter activity
SAG0991	COG0573	inorganic phosphate transmembrane transporter activity
SAG0993	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SAG0993	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAG0994	COG0483	inositol monophosphate 1-phosphatase activity
SAG0997	COG0196	riboflavin kinase activity
SAG0998	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAG1004	COG1136	(ABC) transporter
SAG1005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAG1006	COG0758	DNA mediated transformation
SAG1007	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAG1008	COG4604	ABC transporter, ATP-binding protein
SAG1009	COG4605	iron ion homeostasis
SAG1010	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAG1011	COG0110	maltose O-acetyltransferase activity
SAG1013	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAG1014	COG1376	ErfK ybiS ycfS ynhG family protein
SAG1015	COG1966	Carbon starvation protein
SAG1016	COG3279	Response regulator of the LytR AlgR family
SAG1017	COG3275	phosphorelay sensor kinase activity
SAG1043	COG0505	Belongs to the CarA family
SAG1045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAG1046	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SAG1049	COG0488	(ABC) transporter
SAG1051	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAG1054	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SAG1062	COG0095	Lipoate-protein ligase
SAG1064	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAG1065	COG4684	Psort location CytoplasmicMembrane, score
SAG1066	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAG1068	COG2801	Transposase and inactivated derivatives
SAG1070	COG1132	(ABC) transporter
SAG1076	COG2890	protein-(glutamine-N5) methyltransferase activity
SAG1079	COG1942	4-Oxalocrotonate Tautomerase
SAG1083	COG3976	FMN-binding domain protein
SAG1083	COG1053	succinate dehydrogenase
SAG1083	COG0431	NADPH-dependent FMN reductase
SAG1085	COG2233	PERMEase
SAG1088	COG0477	Major facilitator Superfamily
SAG1091	COG4221	oxidoreductase activity
SAG1092	COG0280	phosphate acetyltransferase
SAG1093	COG0564	pseudouridine synthase activity
SAG1095	COG2357	RelA SpoT domain protein
SAG1098	COG1104	cysteine desulfurase activity
SAG1102	COG0628	permease
SAG1103	COG2723	6-phospho-beta-galactosidase activity
SAG1105	COG0561	phosphatase activity
SAG1107	COG0038	chloride channel
SAG1109	COG1177	transmembrane transport
SAG1110	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAG1112	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAG1113	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAG1117	COG0285	dihydrofolate synthase activity
SAG1118	COG2962	Rard protein
SAG1121	COG0726	polysaccharide deacetylase
SAG1122	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAG1124	COG1012	belongs to the aldehyde dehydrogenase family
SAG1140	COG2261	transglycosylase associated protein
SAG1145	COG1115	amino acid carrier protein
SAG1146	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAG1148	COG1346	cytolysis
SAG1150	COG0539	negative regulation of cytoplasmic translation
SAG1152	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAG1154	COG0187	DNA topoisomerase II activity
SAG1155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SAG1156	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAG1161	COG2089	acid synthase
SAG1164	COG1216	Glycosyl transferase, family 2
SAG1164	COG1442	glycosyl transferase family 8
SAG1165	COG1215	transferase activity, transferring glycosyl groups
SAG1166	COG0463	Glycosyl transferase, family 2
SAG1170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAG1175	COG1316	TRANSCRIPTIONal
SAG1176	COG0583	DNA-binding transcription factor activity
SAG1180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAG1187	COG3842	ATPase activity
SAG1190	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAG1191	COG3527	Alpha-acetolactate decarboxylase
SAG1192	COG0028	Belongs to the TPP enzyme family
SAG1193	COG0457	Tetratricopeptide repeat
SAG1194	COG0628	permease
SAG1196	COG1051	belongs to the nudix hydrolase family
SAG1197	COG5492	domain, Protein
SAG1198	COG1088	dTDP-glucose 4,6-dehydratase activity
SAG1200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SAG1201	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAG1203	COG2384	SAM-dependent methyltransferase
SAG1208	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAG1208	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAG1209	COG0300	oxidoreductase activity
SAG1212	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAG1218	COG1573	uracil-dna glycosylase
SAG1219	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAG1224	COG0534	Mate efflux family protein
SAG1234	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAG1247	COG4974	Belongs to the 'phage' integrase family
SAG1249	COG1396	sequence-specific DNA binding
SAG1250	COG3843	relaxase mobilization nuclease domain protein
SAG1256	COG2801	Transposase and inactivated derivatives
SAG1262	COG2217	Heavy metal translocating P-type atpase
SAG1270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAG1297	COG0270	DNA (cytosine-5-)-methyltransferase activity
SAG1305	COG2040	homocysteine
SAG1306	COG0833	amino acid
SAG1314	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAG1316	COG3425	synthase
SAG1319	COG1272	protein, Hemolysin III
SAG1328	COG0745	RESPONSE REGULATOR receiver
SAG1329	COG2357	RelA SpoT domain protein
SAG1333	COG0737	Belongs to the 5'-nucleotidase family
SAG1334	COG0242	peptide deformylase activity
SAG1335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAG1337	COG1132	(ABC) transporter
SAG1340	COG0488	(ABC) transporter
SAG1346	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAG1346	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAG1346	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAG1347	COG1105	Belongs to the carbohydrate kinase PfkB family
SAG1348	COG1349	DNA-binding transcription factor activity
SAG1349	COG1388	LysM domain
SAG1349	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAG1357	COG1837	Belongs to the UPF0109 family
SAG1358	COG0228	four-way junction DNA binding
SAG1359	COG0577	efflux transmembrane transporter activity
SAG1360	COG1136	(ABC) transporter
SAG1361	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SAG1363	COG0505	Belongs to the CarA family
SAG1365	COG0564	pseudouridine synthase activity
SAG1367	COG0583	DNA-binding transcription factor activity
SAG1373	COG1104	cysteine desulfurase activity
SAG1375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAG1380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAG1381	COG1368	sulfuric ester hydrolase activity
SAG1382	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAG1384	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAG1390	COG2244	polysaccharide biosynthetic process
SAG1392	COG1120	ATPase activity
SAG1393	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAG1394	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAG1395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAG1398	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAG1399	COG1253	flavin adenine dinucleotide binding
SAG1400	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAG1401	COG1242	4 iron, 4 sulfur cluster binding
SAG1402	COG0671	phosphoesterase, PA-phosphatase related
SAG1403	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAG1410	COG0297	glycogen (starch) synthase activity
SAG1418	COG3475	LICD family
SAG1421	COG0463	Glycosyl transferase, family 2
SAG1422	COG1215	transferase activity, transferring glycosyl groups
SAG1424	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAG1425	COG2151	metal-sulfur cluster biosynthetic enzyme
SAG1426	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAG1427	COG0358	DNA primase activity
SAG1428	COG1970	mechanosensitive ion channel activity
SAG1431	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAG1432	COG0004	ammonium transporteR
SAG1434	COG1054	Belongs to the UPF0176 family
SAG1436	COG2271	Major facilitator Superfamily
SAG1438	COG0058	SHG alpha-glucan phosphorylase activity
SAG1439	COG1640	4-alpha-glucanotransferase
SAG1440	COG1609	Transcriptional regulator
SAG1442	COG1175	transmembrane transport
SAG1443	COG3833	ABC-type maltose transport systems, permease component
SAG1444	COG3104	oligopeptide transport
SAG1448	COG0438	transferase activity, transferring glycosyl groups
SAG1453	COG0201	protein transport
SAG1454	COG1442	glycosyl transferase family 8
SAG1455	COG1442	glycosyl transferase family 8
SAG1455	COG1216	Glycosyl transferase, family 2
SAG1456	COG1442	glycosyl transferase family 8
SAG1459	COG1442	glycosyl transferase family 8
SAG1459	COG1216	Glycosyl transferase, family 2
SAG1460	COG1442	glycosyl transferase family 8
SAG1466	COG0765	amino acid transport
SAG1467	COG1126	abc transporter atp-binding protein
SAG1472	COG2309	aminopeptidase activity
SAG1474	COG0154	amidase activity
SAG1475	COG1187	pseudouridine synthase activity
SAG1476	COG0656	L-ascorbic acid biosynthetic process
SAG1477	COG0778	Nitroreductase
SAG1478	COG0346	lactoylglutathione lyase activity
SAG1479	COG0463	Glycosyl transferase, family 2
SAG1480	COG1113	amino acid transport
SAG1481	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAG1482	COG0557	exoribonuclease II activity
SAG1485	COG2814	Major facilitator Superfamily
SAG1487	COG1131	(ABC) transporter
SAG1489	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAG1490	COG1396	sequence-specific DNA binding
SAG1500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SAG1501	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAG1507	COG1702	phosphate starvation-inducible protein PhoH
SAG1512	COG0233	cytoplasmic translational termination
SAG1515	COG0444	Belongs to the ABC transporter superfamily
SAG1516	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAG1517	COG0601	transmembrane transport
SAG1518	COG0747	negative chemotaxis
SAG1519	COG0081	regulation of translation
SAG1523	COG1473	amidohydrolase
SAG1524	COG0583	DNA-binding transcription factor activity
SAG1527	COG2801	Transposase and inactivated derivatives
SAG1528	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAG1530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAG1535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAG1542	COG0673	inositol 2-dehydrogenase activity
SAG1544	COG1028	Short-chain dehydrogenase reductase Sdr
SAG1556	COG1114	Component of the transport system for branched-chain amino acids
SAG1557	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAG1557	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAG1561	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAG1563	COG0708	Exodeoxyribonuclease III
SAG1564	COG1393	Belongs to the ArsC family
SAG1565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAG1566	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAG1574	COG0470	DNA polymerase III
SAG1577	COG0517	IMP dehydrogenase activity
SAG1581	COG0559	Belongs to the binding-protein-dependent transport system permease family
SAG1584	COG5433	transposase activity
SAG1586	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAG1587	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAG1589	COG0531	amino acid
SAG1590	COG0569	domain protein
SAG1591	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAG1593	COG1187	pseudouridine synthase activity
SAG1603	COG1827	regulation of RNA biosynthetic process
SAG1606	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAG1607	COG1254	Belongs to the acylphosphatase family
SAG1609	COG0765	amino acid transport
SAG1610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAG1613	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SAG1619	COG5433	transposase activity
SAG1621	COG1484	DNA-dependent DNA replication
SAG1624	COG5002	protein histidine kinase activity
SAG1625	COG0745	RESPONSE REGULATOR receiver
SAG1628	COG1704	LemA family
SAG1630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAG1631	COG0569	domain protein
SAG1636	COG1114	Component of the transport system for branched-chain amino acids
SAG1637	COG1063	alcohol dehydrogenase
SAG1642	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAG1643	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAG1645	COG0217	transcriptional regulatory protein
SAG1647	COG2376	Dihydroxyacetone kinase
SAG1648	COG1309	transcriptional regulator
SAG1650	COG2376	Dihydroxyacetone kinase
SAG1651	COG1461	Dihydroxyacetone kinase
SAG1652	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAG1653	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAG1655	COG0789	Transcriptional regulator
SAG1658	COG2226	methyltransferase
SAG1659	COG0799	negative regulation of ribosome biogenesis
SAG1661	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAG1662	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAG1663	COG1534	Rna-binding protein
SAG1664	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAG1665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAG1670	COG0574	Belongs to the PEP-utilizing enzyme family
SAG1670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAG1672	COG0517	IMP dehydrogenase activity
SAG1674	COG1335	isochorismatase
SAG1675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SAG1676	COG0436	Aminotransferase
SAG1677	COG0589	response to stress
SAG1678	COG0561	phosphatase activity
SAG1679	COG0252	asparaginase activity
SAG1681	COG4989	oxidoreductase activity
SAG1682	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAG1683	COG3942	CHAP domain
SAG1683	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAG1685	COG0736	holo-[acyl-carrier-protein] synthase activity
SAG1686	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SAG1688	COG1482	cell wall glycoprotein biosynthetic process
SAG1689	COG1940	carbohydrate kinase activity
SAG1690	COG1263	PTS System
SAG1690	COG2190	(PTS) system
SAG1690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG1691	COG1621	beta-fructofuranosidase activity
SAG1692	COG1609	Transcriptional regulator
SAG1693	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAG1695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAG1704	COG2131	deaminase
SAG1707	COG2814	Major facilitator Superfamily
SAG1713	COG0629	single-stranded DNA binding
SAG1714	COG0360	Binds together with S18 to 16S ribosomal RNA
SAG1715	COG1194	a g-specific adenine glycosylase
SAG1717	COG3118	belongs to the thioredoxin family
SAG1723	COG0681	Belongs to the peptidase S26 family
SAG1724	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAG1727	COG1882	Formate acetyltransferase
SAG1728	COG3576	pyridoxamine 5-phosphate
SAG1729	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAG1732	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAG1734	COG2814	Major facilitator Superfamily
SAG1735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAG1738	COG0142	geranyltranstransferase activity
SAG1739	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAG1740	COG4988	ABC transporter
SAG1741	COG1294	oxidase, subunit
SAG1742	COG1271	oxidase subunit
SAG1743	COG1252	NADH dehydrogenase
SAG1747	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAG1748	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAG1749	COG0789	Transcriptional regulator
SAG1752	COG2081	HI0933 family
SAG1758	COG0456	acetyltransferase
SAG1759	COG1214	PFAM Peptidase M22, glycoprotease
SAG1762	COG3942	CHAP domain
SAG1763	COG0174	glutamine synthetase
SAG1764	COG0789	Transcriptional regulator
SAG1767	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAG1772	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAG1782	COG0084	hydrolase, TatD family'
SAG1787	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAG1788	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAG1789	COG1696	Membrane protein involved in D-alanine export
SAG1792	COG0745	RESPONSE REGULATOR receiver
SAG1794	COG3314	Sporulation integral membrane protein YlbJ
SAG1797	COG4175	Glycine betaine
SAG1797	COG3448	diguanylate cyclase activity
SAG1799	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SAG1803	COG1070	Carbohydrate kinase
SAG1805	COG3775	system Galactitol-specific IIC component
SAG1806	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAG1808	COG1609	Transcriptional regulator
SAG1818	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SAG1824	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SAG1825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAG1826	COG1428	Deoxynucleoside kinase
SAG1828	COG0542	response to heat
SAG1829	COG4463	regulation of RNA biosynthetic process
SAG1831	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAG1833	COG0450	alkyl hydroperoxide reductase
SAG1859	COG0582	viral genome integration into host DNA
SAG1873	COG0305	Participates in initiation and elongation during chromosome replication
SAG1882	COG1396	sequence-specific DNA binding
SAG1885	COG4974	Belongs to the 'phage' integrase family
SAG1887	COG0025	NhaP-type Na H and K H
SAG1889	COG1619	proteins homologs of microcin C7 resistance protein MccF
SAG1890	COG3590	peptidase
SAG1896	COG1609	Transcriptional regulator
SAG1898	COG3716	PTS system mannose fructose sorbose family IID component
SAG1899	COG3715	PTS system
SAG1900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG1901	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAG1904	COG1028	Short-chain dehydrogenase reductase Sdr
SAG1911	COG2176	DNA-directed DNA polymerase activity
SAG1912	COG1388	LysM domain
SAG1912	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAG1915	COG4589	Belongs to the CDS family
SAG1917	COG1862	Preprotein translocase
SAG1920	COG3493	citrate carrier protein
SAG1921	COG3290	protein histidine kinase activity
SAG1922	COG4565	transcriptional regulatory protein
SAG1923	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAG1925	COG3842	ATPase activity
SAG1939	COG1490	D-aminoacyl-tRNA deacylase activity
SAG1941	COG0737	Belongs to the 5'-nucleotidase family
SAG1943	COG1363	Peptidase, m42
SAG1946	COG2207	Transcriptional regulator
SAG1946	COG4753	response regulator
SAG1947	COG2972	Histidine kinase
SAG1948	COG3716	PTS system mannose fructose sorbose family IID component
SAG1949	COG3715	PTS system
SAG1955	COG1131	(ABC) transporter
SAG1957	COG3279	Response regulator of the LytR AlgR family
SAG1959	COG2190	(PTS) system
SAG1959	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAG1959	COG1263	PTS System
SAG1960	COG5002	protein histidine kinase activity
SAG1961	COG0745	RESPONSE REGULATOR receiver
SAG1963	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAG1964	COG0581	inorganic phosphate transmembrane transporter activity
SAG1965	COG0573	inorganic phosphate transmembrane transporter activity
SAG1968	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAG1972	COG0789	Transcriptional regulator
SAG1977	COG0456	acetyltransferase
SAG1978	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAG1980	COG1131	(ABC) transporter
SAG1982	COG1395	domain, Protein
SAG1983	COG1694	Mazg nucleotide pyrophosphohydrolase
SAG1984	COG1611	Belongs to the LOG family
SAG1988	COG2946	Replication initiation factor
SAG1993	COG0582	viral genome integration into host DNA
SAG2001	COG0433	COG0433 Predicted ATPase
SAG2008	COG4115	mRNA cleavage
SAG2015	COG3620	sequence-specific DNA binding
SAG2018	COG1674	ftsk spoiiie
SAG2025	COG1914	H( )-stimulated, divalent metal cation uptake system
SAG2027	COG1131	(ABC) transporter
SAG2035	COG1131	(ABC) transporter
SAG2037	COG1396	sequence-specific DNA binding
SAG2039	COG1694	Mazg nucleotide pyrophosphohydrolase
SAG2046	COG0371	Dehydrogenase
SAG2048	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAG2048	COG0646	methionine synthase
SAG2049	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SAG2051	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SAG2054	COG0745	RESPONSE REGULATOR receiver
SAG2055	COG2205	protein histidine kinase activity
SAG2055	COG2770	Histidine kinase
SAG2057	COG0495	leucyl-tRNA aminoacylation
SAG2058	COG2814	Major facilitator Superfamily
SAG2059	COG4667	esterase of the alpha-beta hydrolase superfamily
SAG2060	COG1442	glycosyl transferase family 8
SAG2061	COG1442	glycosyl transferase family 8
SAG2066	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAG2067	COG0564	pseudouridine synthase activity
SAG2071	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAG2072	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SAG2075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAG2076	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SAG2076	COG1116	anion transmembrane transporter activity
SAG2077	COG4120	Belongs to the binding-protein-dependent transport system permease family
SAG2079	COG0561	phosphatase activity
SAG2080	COG2514	catechol 2,3-dioxygenase activity
SAG2082	COG0602	queuosine metabolic process
SAG2086	COG1328	CTP reductase activity
SAG2090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAG2092	COG1393	Belongs to the ArsC family
SAG2093	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SAG2095	COG2818	Glycosylase
SAG2098	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SAG2105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAG2106	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAG2108	COG0124	histidyl-tRNA synthetase
SAG2110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAG2112	COG4974	Belongs to the 'phage' integrase family
SAG2114	COG2946	Replication initiation factor
SAG2119	COG3177	Filamentation induced by cAMP protein fic
SAG2122	COG0745	RESPONSE REGULATOR receiver
SAG2123	COG5002	protein histidine kinase activity
SAG2124	COG1288	antiporter activity
SAG2126	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAG2127	COG3852	Histidine kinase
SAG2128	COG0784	Response regulator, receiver
SAG2129	COG1125	glycine betaine transport
SAG2129	COG0517	IMP dehydrogenase activity
SAG2130	COG1174	glycine betaine transport
SAG2131	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAG2131	COG0392	lysyltransferase activity
SAG2133	COG3759	membrane
SAG2139	COG0305	Participates in initiation and elongation during chromosome replication
SAG2142	COG0445	tRNA wobble uridine modification
SAG2143	COG2095	MarC family integral membrane protein
SAG2144	COG0482	sulfurtransferase activity
SAG2145	COG1760	l-serine dehydratase
SAG2146	COG1760	l-serine dehydratase
SAG2147	COG0741	lytic transglycosylase activity
SAG2152	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAG2153	COG0612	Peptidase, M16
SAG2154	COG0612	Peptidase, M16
SAG2155	COG2501	S4 domain
SAG2159	COG0516	GMP reductase activity
SAG2159	COG0517	IMP dehydrogenase activity
SAG2161	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAG2164	COG0454	-acetyltransferase
SAG2165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAG2170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAG2171	COG0488	(ABC) transporter
SAG2172	COG4485	Bacterial membrane protein, YfhO
SAG2173	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SAG2174	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAG2175	COG1475	DNA binding
SAG_RS02360	COG2217	Heavy metal translocating P-type atpase