locus-tag	class	description
CHF17_RS00010	COG0592	DNA-directed DNA polymerase activity
CHF17_RS00015	COG1597	lipid kinase activity
CHF17_RS00030	COG0012	GTP binding
CHF17_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHF17_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHF17_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHF17_RS00265	COG0436	Aminotransferase
CHF17_RS00280	COG0416	fatty acid biosynthetic process
CHF17_RS00285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHF17_RS00290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHF17_RS00295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHF17_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHF17_RS00320	COG0138	bifunctional purine biosynthesis protein purh
CHF17_RS00345	COG1175	transmembrane transport
CHF17_RS00350	COG0395	ABC-type sugar transport system, permease component
CHF17_RS00365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHF17_RS00375	COG3458	cephalosporin-C deacetylase activity
CHF17_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHF17_RS00410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHF17_RS00425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHF17_RS00435	COG2755	lipolytic protein G-D-S-L family
CHF17_RS00435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHF17_RS00440	COG1454	alcohol dehydrogenase
CHF17_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
CHF17_RS00445	COG1064	alcohol dehydrogenase
CHF17_RS00455	COG0534	Mate efflux family protein
CHF17_RS00565	COG0201	protein transport
CHF17_RS00570	COG0563	adenylate kinase activity
CHF17_RS00585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHF17_RS00595	COG0202	RNA polymerase activity
CHF17_RS00885	COG1598	PFAM Uncharacterised protein family UPF0150
CHF17_RS00925	COG0740	serine-type endopeptidase activity
CHF17_RS01030	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHF17_RS01035	COG1420	regulation of RNA biosynthetic process
CHF17_RS01045	COG0443	Heat shock 70 kDa protein
CHF17_RS01055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHF17_RS01065	COG0351	phosphomethylpyrimidine kinase
CHF17_RS01070	COG4720	Psort location CytoplasmicMembrane, score
CHF17_RS01080	COG0668	transmembrane transport
CHF17_RS01110	COG0756	dUTP diphosphatase activity
CHF17_RS01125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHF17_RS01135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHF17_RS01140	COG1879	ABC-type sugar transport system periplasmic component
CHF17_RS01145	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHF17_RS01160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHF17_RS01165	COG1609	Transcriptional regulator
CHF17_RS01175	COG0577	efflux transmembrane transporter activity
CHF17_RS01180	COG1136	(ABC) transporter
CHF17_RS01185	COG0745	RESPONSE REGULATOR receiver
CHF17_RS01190	COG5002	protein histidine kinase activity
CHF17_RS01195	COG0137	argininosuccinate synthase activity
CHF17_RS01205	COG0191	fructose-bisphosphate aldolase activity
CHF17_RS01225	COG1461	Dihydroxyacetone kinase
CHF17_RS01245	COG1126	abc transporter atp-binding protein
CHF17_RS01250	COG0765	amino acid transport
CHF17_RS01270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHF17_RS01280	COG0719	Fe-S assembly protein
CHF17_RS01285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHF17_RS01295	COG0719	Fe-S assembly protein
CHF17_RS01300	COG1686	Belongs to the peptidase S11 family
CHF17_RS01305	COG1686	Belongs to the peptidase S11 family
CHF17_RS01310	COG4166	transmembrane transport
CHF17_RS01315	COG0601	transmembrane transport
CHF17_RS01320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHF17_RS01325	COG0444	Belongs to the ABC transporter superfamily
CHF17_RS01330	COG4608	Belongs to the ABC transporter superfamily
CHF17_RS01370	COG1121	(ABC) transporter
CHF17_RS01375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHF17_RS01390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHF17_RS01390	COG4499	WXG100 protein secretion system (Wss), protein YukC
CHF17_RS01420	COG1459	type II secretion system
CHF17_RS01465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHF17_RS01470	COG1363	Peptidase, m42
CHF17_RS01485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHF17_RS01490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHF17_RS01505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHF17_RS01525	COG1346	cytolysis
CHF17_RS01540	COG0601	transmembrane transport
CHF17_RS01545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHF17_RS01550	COG1122	ATPase activity
CHF17_RS01560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHF17_RS01560	COG1263	PTS System
CHF17_RS01565	COG0366	Alpha amylase catalytic
CHF17_RS01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHF17_RS01585	COG3959	Transketolase, thiamine diphosphate binding domain
CHF17_RS01590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHF17_RS01595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHF17_RS01605	COG1185	polyribonucleotide nucleotidyltransferase activity
CHF17_RS01615	COG1045	serine acetyltransferase
CHF17_RS01625	COG0215	cysteine-tRNA ligase activity
CHF17_RS01630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CHF17_RS01655	COG1476	TRANSCRIPTIONal
CHF17_RS01660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHF17_RS01670	COG0582	viral genome integration into host DNA
CHF17_RS01675	COG1396	sequence-specific DNA binding
CHF17_RS01715	COG5290	Psort location Cytoplasmic, score
CHF17_RS01735	COG1396	sequence-specific DNA binding
CHF17_RS01745	COG2814	Major facilitator Superfamily
CHF17_RS01755	COG1732	Glycine betaine
CHF17_RS01925	COG1695	Transcriptional regulator
CHF17_RS01940	COG1755	Isoprenylcysteine carboxyl methyltransferase
CHF17_RS01980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHF17_RS01985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHF17_RS02005	COG1131	(ABC) transporter
CHF17_RS02020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHF17_RS02025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHF17_RS02030	COG0275	rRNA processing
CHF17_RS02040	COG0768	penicillin binding
CHF17_RS02050	COG0513	Belongs to the DEAD box helicase family
CHF17_RS02065	COG1126	abc transporter atp-binding protein
CHF17_RS02075	COG0492	ferredoxin-NADP+ reductase activity
CHF17_RS02080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHF17_RS02090	COG3579	cysteine-type endopeptidase activity
CHF17_RS02095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHF17_RS02125	COG0116	Belongs to the methyltransferase superfamily
CHF17_RS02135	COG1854	S-ribosylhomocysteine lyase activity
CHF17_RS02140	COG1418	mRNA catabolic process
CHF17_RS02140	COG4372	Transposase
CHF17_RS02150	COG1131	(ABC) transporter
CHF17_RS02160	COG4585	Histidine kinase
CHF17_RS02165	COG2197	response regulator
CHF17_RS02175	COG0194	GDP metabolic process
CHF17_RS02185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHF17_RS02190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHF17_RS02195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHF17_RS02195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHF17_RS02205	COG2815	serine threonine protein kinase
CHF17_RS02205	COG0515	serine threonine protein kinase
CHF17_RS02215	COG4585	Histidine kinase
CHF17_RS02220	COG2197	response regulator
CHF17_RS02230	COG1098	S1 RNA binding domain
CHF17_RS02235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHF17_RS02240	COG1349	DNA-binding transcription factor activity
CHF17_RS02250	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHF17_RS02260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHF17_RS02265	COG1882	Formate acetyltransferase
CHF17_RS02285	COG1739	Uncharacterized protein family UPF0029
CHF17_RS02290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CHF17_RS02300	COG1040	competence protein
CHF17_RS02335	COG0527	aspartate kinase activity
CHF17_RS02340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHF17_RS02345	COG1024	Enoyl-CoA hydratase
CHF17_RS02355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHF17_RS02365	COG2070	2-Nitropropane dioxygenase
CHF17_RS02370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHF17_RS02375	COG1028	Short-chain dehydrogenase reductase Sdr
CHF17_RS02380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHF17_RS02395	COG0439	Biotin carboxylase
CHF17_RS02415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHF17_RS02430	COG3716	PTS system mannose fructose sorbose family IID component
CHF17_RS02435	COG3715	PTS system
CHF17_RS02450	COG0561	phosphatase activity
CHF17_RS02465	COG2252	PERMEase
CHF17_RS02470	COG0802	atpase or kinase
CHF17_RS02480	COG1316	TRANSCRIPTIONal
CHF17_RS02490	COG0537	adenosine 5'-monophosphoramidase activity
CHF17_RS02505	COG1131	(ABC) transporter
CHF17_RS02510	COG4473	ABC transporter
CHF17_RS02520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHF17_RS02535	COG0195	Participates in both transcription termination and antitermination
CHF17_RS02540	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CHF17_RS02550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHF17_RS02555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHF17_RS02580	COG2860	membrane
CHF17_RS02590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHF17_RS02590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHF17_RS02595	COG1832	CoA-binding protein
CHF17_RS02615	COG5002	protein histidine kinase activity
CHF17_RS02635	COG1268	BioY protein
CHF17_RS02640	COG1234	tRNA 3'-trailer cleavage
CHF17_RS02655	COG0166	Belongs to the GPI family
CHF17_RS02660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHF17_RS02665	COG0705	Rhomboid family
CHF17_RS02665	COG0457	Tetratricopeptide repeat
CHF17_RS02670	COG1744	ABC transporter substrate-binding protein PnrA-like
CHF17_RS02675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHF17_RS02690	COG0706	membrane insertase activity
CHF17_RS02765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHF17_RS02775	COG2153	protein acetylation
CHF17_RS02785	COG1216	Glycosyl transferase, family 2
CHF17_RS02785	COG1442	glycosyl transferase family 8
CHF17_RS02840	COG0789	Transcriptional regulator
CHF17_RS02850	COG0656	L-ascorbic acid biosynthetic process
CHF17_RS02875	COG3328	transposase activity
CHF17_RS02900	COG0582	viral genome integration into host DNA
CHF17_RS02955	COG0673	inositol 2-dehydrogenase activity
CHF17_RS02965	COG2315	Protein conserved in bacteria
CHF17_RS02980	COG0742	ribosomal rna small subunit methyltransferase
CHF17_RS02995	COG3480	Lon protease (S16) C-terminal proteolytic domain
CHF17_RS03000	COG0737	Belongs to the 5'-nucleotidase family
CHF17_RS03005	COG4470	Protein conserved in bacteria
CHF17_RS03010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHF17_RS03020	COG1132	(ABC) transporter
CHF17_RS03025	COG1132	(ABC) transporter
CHF17_RS03030	COG0512	Glutamine amidotransferase of anthranilate synthase
CHF17_RS03040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHF17_RS03060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHF17_RS03075	COG1940	carbohydrate kinase activity
CHF17_RS03080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHF17_RS03085	COG1217	gtp-binding protein TYPA
CHF17_RS03095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHF17_RS03120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHF17_RS03130	COG0762	integral membrane protein
CHF17_RS03135	COG2302	S4 RNA-binding domain
CHF17_RS03140	COG3599	regulation of cell shape
CHF17_RS03145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHF17_RS03155	COG0494	nUDIX hydrolase
CHF17_RS03160	COG0542	response to heat
CHF17_RS03165	COG4703	Protein of unknown function (DUF1797)
CHF17_RS03170	COG0765	amino acid transport
CHF17_RS03175	COG1126	abc transporter atp-binding protein
CHF17_RS03180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHF17_RS03190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHF17_RS03195	COG1570	exodeoxyribonuclease VII activity
CHF17_RS03200	COG1722	exodeoxyribonuclease VII activity
CHF17_RS03210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHF17_RS03215	COG1438	arginine binding
CHF17_RS03220	COG0497	DNA recombination
CHF17_RS03225	COG1307	EDD domain protein, DegV family
CHF17_RS03230	COG2755	lipolytic protein G-D-S-L family
CHF17_RS03275	COG1078	dGTPase activity
CHF17_RS03300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHF17_RS03310	COG2884	Cell division ATP-binding protein ftsE
CHF17_RS03315	COG2177	Part of the ABC transporter FtsEX involved in
CHF17_RS03340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHF17_RS03340	COG1199	ATP-dependent helicase activity
CHF17_RS03345	COG0436	Aminotransferase
CHF17_RS03350	COG0017	Asparaginyl-tRNA synthetase
CHF17_RS03370	COG1660	Displays ATPase and GTPase activities
CHF17_RS03395	COG0254	rRNA binding
CHF17_RS03400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHF17_RS03405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHF17_RS03410	COG0716	FMN binding
CHF17_RS03415	COG1605	Chorismate mutase
CHF17_RS03415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CHF17_RS03420	COG0038	chloride channel
CHF17_RS03425	COG0335	large ribosomal subunit rRNA binding
CHF17_RS03475	COG1136	(ABC) transporter
CHF17_RS03490	COG5002	protein histidine kinase activity
CHF17_RS03510	COG0772	Belongs to the SEDS family
CHF17_RS03530	COG0560	Phosphoserine phosphatase
CHF17_RS03545	COG0148	phosphopyruvate hydratase activity
CHF17_RS03565	COG1316	TRANSCRIPTIONal
CHF17_RS03590	COG1484	DNA-dependent DNA replication
CHF17_RS03650	COG0551	DNA topoisomerase type I activity
CHF17_RS03650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHF17_RS03685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHF17_RS03725	COG2375	cellular response to nickel ion
CHF17_RS03725	COG1132	(ABC) transporter
CHF17_RS03730	COG1132	(ABC) transporter
CHF17_RS03745	COG1129	ABC transporter
CHF17_RS03765	COG1674	ftsk spoiiie
CHF17_RS03775	COG2946	Replication initiation factor
CHF17_RS03805	COG0741	lytic transglycosylase activity
CHF17_RS03805	COG0791	NLP P60 protein
CHF17_RS03880	COG0534	Mate efflux family protein
CHF17_RS03915	COG3700	Belongs to the class B bacterial acid phosphatase family
CHF17_RS04015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHF17_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
CHF17_RS04050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHF17_RS04055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHF17_RS04075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHF17_RS04080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHF17_RS04100	COG3064	Membrane
CHF17_RS04100	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHF17_RS04115	COG3590	peptidase
CHF17_RS04120	COG3590	peptidase
CHF17_RS04160	COG1136	(ABC) transporter
CHF17_RS04175	COG0586	Pfam SNARE associated Golgi protein
CHF17_RS04180	COG4619	ABC transporter
CHF17_RS04185	COG0390	transport system, permease component
CHF17_RS04195	COG0583	DNA-binding transcription factor activity
CHF17_RS04210	COG2211	Major facilitator Superfamily
CHF17_RS04220	COG3250	beta-galactosidase activity
CHF17_RS04225	COG2186	Transcriptional regulator
CHF17_RS04230	COG0800	Aldolase
CHF17_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
CHF17_RS04265	COG1609	Transcriptional regulator
CHF17_RS04280	COG0438	transferase activity, transferring glycosyl groups
CHF17_RS04305	COG0765	amino acid transport
CHF17_RS04310	COG0765	amino acid transport
CHF17_RS04315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHF17_RS04320	COG1126	abc transporter atp-binding protein
CHF17_RS04325	COG0745	RESPONSE REGULATOR receiver
CHF17_RS04330	COG5002	protein histidine kinase activity
CHF17_RS04335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHF17_RS04340	COG2832	Protein of unknown function (DUF454)
CHF17_RS04350	COG1196	nuclear chromosome segregation
CHF17_RS04355	COG0561	phosphatase activity
CHF17_RS04360	COG0561	phosphatase activity
CHF17_RS04365	COG0552	protein localization to endoplasmic reticulum
CHF17_RS04375	COG3689	TIGRFAM TIGR03943 family protein
CHF17_RS04380	COG0701	Predicted permease
CHF17_RS04395	COG2183	response to ionizing radiation
CHF17_RS04400	COG3091	SprT-like family
CHF17_RS04405	COG1983	PspC domain protein
CHF17_RS04445	COG0826	peptidase U32
CHF17_RS04450	COG4443	Transcriptional Coactivator p15 (PC4)
CHF17_RS04460	COG1914	H( )-stimulated, divalent metal cation uptake system
CHF17_RS04500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHF17_RS04525	COG1164	Oligoendopeptidase f
CHF17_RS04535	COG0772	Belongs to the SEDS family
CHF17_RS04555	COG0768	penicillin binding
CHF17_RS04570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHF17_RS04575	COG2223	nitrite transmembrane transporter activity
CHF17_RS04600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHF17_RS04605	COG2011	ABC-type metal ion transport system permease component
CHF17_RS04610	COG1464	Belongs to the NlpA lipoprotein family
CHF17_RS04615	COG0513	Belongs to the DEAD box helicase family
CHF17_RS04625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHF17_RS04630	COG0204	Acyl-transferase
CHF17_RS04635	COG1555	photosystem II stabilization
CHF17_RS04635	COG1596	polysaccharide export
CHF17_RS04640	COG0658	competence protein
CHF17_RS04640	COG2333	competence protein COMEC
CHF17_RS04645	COG0561	phosphatase activity
CHF17_RS04650	COG1609	Transcriptional regulator
CHF17_RS04655	COG0657	acetylesterase activity
CHF17_RS04660	COG2226	methyltransferase
CHF17_RS04670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHF17_RS04675	COG3711	transcriptional antiterminator
CHF17_RS04680	COG2190	(PTS) system
CHF17_RS04680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHF17_RS04680	COG1263	PTS System
CHF17_RS04690	COG3835	regulator
CHF17_RS04695	COG1929	Belongs to the glycerate kinase type-1 family
CHF17_RS04700	COG2610	gluconate transmembrane transporter activity
CHF17_RS04710	COG1846	Transcriptional regulator
CHF17_RS04715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHF17_RS04725	COG0363	glucosamine-6-phosphate deaminase activity
CHF17_RS04730	COG0435	Glutathione S-transferase
CHF17_RS04735	COG1187	pseudouridine synthase activity
CHF17_RS04760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHF17_RS04765	COG4122	O-methyltransferase activity
CHF17_RS04770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHF17_RS04775	COG4894	glucomannan catabolic process
CHF17_RS04780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHF17_RS04785	COG1811	Na channel or pump
CHF17_RS04790	COG1442	glycosyl transferase family 8
CHF17_RS04805	COG1476	TRANSCRIPTIONal
CHF17_RS04820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHF17_RS04825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHF17_RS04830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHF17_RS04845	COG1012	belongs to the aldehyde dehydrogenase family
CHF17_RS04850	COG0726	polysaccharide deacetylase
CHF17_RS04855	COG0513	Belongs to the DEAD box helicase family
CHF17_RS04865	COG1956	GAF domain-containing protein
CHF17_RS04870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHF17_RS04880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHF17_RS04880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHF17_RS04910	COG4721	ABC-type cobalt transport system, permease component
CHF17_RS04915	COG1122	ATPase activity
CHF17_RS04925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CHF17_RS04945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHF17_RS04955	COG4109	DRTGG domain
CHF17_RS04960	COG0024	Methionine aminopeptidase
CHF17_RS04970	COG2246	polysaccharide biosynthetic process
CHF17_RS04975	COG4708	membrane
CHF17_RS04980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHF17_RS04985	COG1597	lipid kinase activity
CHF17_RS04990	COG1523	belongs to the glycosyl hydrolase 13 family
CHF17_RS05050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHF17_RS05060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHF17_RS05085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHF17_RS05085	COG0072	phenylalanine-tRNA ligase activity
CHF17_RS05090	COG2321	neutral zinc metallopeptidase
CHF17_RS05095	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHF17_RS05100	COG1074	ATP-dependent DNA helicase activity
CHF17_RS05110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHF17_RS05115	COG0488	(ABC) transporter
CHF17_RS05120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHF17_RS05125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHF17_RS05125	COG0022	dehydrogenase e1 component
CHF17_RS05130	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHF17_RS05140	COG0095	Lipoate-protein ligase
CHF17_RS05150	COG3344	reverse transcriptase
CHF17_RS05155	COG3442	glutamine amidotransferase
CHF17_RS05160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHF17_RS05165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CHF17_RS05190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHF17_RS05200	COG0647	UMP catabolic process
CHF17_RS05210	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CHF17_RS05215	COG1518	maintenance of DNA repeat elements
CHF17_RS05220	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CHF17_RS05240	COG0481	GTPase activity
CHF17_RS05250	COG1418	mRNA catabolic process
CHF17_RS05255	COG0456	acetyltransferase
CHF17_RS05265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHF17_RS05295	COG1131	(ABC) transporter
CHF17_RS05300	COG1725	Transcriptional regulator
CHF17_RS05310	COG0205	6-phosphofructokinase activity
CHF17_RS05315	COG0469	pyruvate kinase activity
CHF17_RS05330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHF17_RS05335	COG2824	Alkylphosphonate utilization operon protein PhnA
CHF17_RS05340	COG0765	amino acid transport
CHF17_RS05345	COG1126	abc transporter atp-binding protein
CHF17_RS05360	COG1072	(Pantothenic acid kinase))
CHF17_RS05365	COG2813	Specifically methylates the guanine in position
CHF17_RS05375	COG1744	ABC transporter substrate-binding protein PnrA-like
CHF17_RS05380	COG3845	ABC transporter
CHF17_RS05385	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHF17_RS05390	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHF17_RS05410	COG3764	Sortase (surface protein transpeptidase)
CHF17_RS05415	COG0346	lactoylglutathione lyase activity
CHF17_RS05435	COG2188	Transcriptional regulator
CHF17_RS05450	COG1464	Belongs to the NlpA lipoprotein family
CHF17_RS05465	COG1136	(ABC) transporter
CHF17_RS05475	COG0745	RESPONSE REGULATOR receiver
CHF17_RS05480	COG5002	protein histidine kinase activity
CHF17_RS05485	COG4974	Belongs to the 'phage' integrase family
CHF17_RS05490	COG4166	transmembrane transport
CHF17_RS05505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHF17_RS05510	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CHF17_RS05515	COG5002	protein histidine kinase activity
CHF17_RS05520	COG0745	RESPONSE REGULATOR receiver
CHF17_RS05530	COG0704	Plays a role in the regulation of phosphate uptake
CHF17_RS05535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHF17_RS05540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHF17_RS05545	COG0581	inorganic phosphate transmembrane transporter activity
CHF17_RS05550	COG0573	inorganic phosphate transmembrane transporter activity
CHF17_RS05560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHF17_RS05560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CHF17_RS05565	COG0483	inositol monophosphate 1-phosphatase activity
CHF17_RS05570	COG4476	Belongs to the UPF0223 family
CHF17_RS05580	COG0196	riboflavin kinase activity
CHF17_RS05585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHF17_RS05615	COG1136	(ABC) transporter
CHF17_RS05620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHF17_RS05625	COG0758	DNA mediated transformation
CHF17_RS05630	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CHF17_RS05635	COG4604	ABC transporter, ATP-binding protein
CHF17_RS05640	COG4605	iron ion homeostasis
CHF17_RS05645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHF17_RS05650	COG0110	maltose O-acetyltransferase activity
CHF17_RS05660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHF17_RS05665	COG1376	ErfK ybiS ycfS ynhG family protein
CHF17_RS05670	COG1966	Carbon starvation protein
CHF17_RS05675	COG3279	Response regulator of the LytR AlgR family
CHF17_RS05680	COG3275	phosphorelay sensor kinase activity
CHF17_RS05780	COG0505	Belongs to the CarA family
CHF17_RS05795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHF17_RS05810	COG0488	(ABC) transporter
CHF17_RS05820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHF17_RS05830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHF17_RS05870	COG0095	Lipoate-protein ligase
CHF17_RS05880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHF17_RS05885	COG4684	Psort location CytoplasmicMembrane, score
CHF17_RS05890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHF17_RS05900	COG1132	(ABC) transporter
CHF17_RS05930	COG2890	protein-(glutamine-N5) methyltransferase activity
CHF17_RS05935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHF17_RS05945	COG1942	4-Oxalocrotonate Tautomerase
CHF17_RS05960	COG1053	succinate dehydrogenase
CHF17_RS05960	COG0431	NADPH-dependent FMN reductase
CHF17_RS05960	COG3976	FMN-binding domain protein
CHF17_RS05970	COG2233	PERMEase
CHF17_RS05985	COG0477	Major facilitator Superfamily
CHF17_RS06005	COG0280	phosphate acetyltransferase
CHF17_RS06010	COG0564	pseudouridine synthase activity
CHF17_RS06020	COG2357	RelA SpoT domain protein
CHF17_RS06035	COG1104	cysteine desulfurase activity
CHF17_RS06045	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CHF17_RS06050	COG2003	Belongs to the UPF0758 family
CHF17_RS06055	COG0628	permease
CHF17_RS06060	COG2723	6-phospho-beta-galactosidase activity
CHF17_RS06070	COG0561	phosphatase activity
CHF17_RS06085	COG0038	chloride channel
CHF17_RS06095	COG1177	transmembrane transport
CHF17_RS06100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHF17_RS06110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHF17_RS06135	COG0285	dihydrofolate synthase activity
CHF17_RS06140	COG2962	Rard protein
CHF17_RS06165	COG1012	belongs to the aldehyde dehydrogenase family
CHF17_RS06240	COG2261	transglycosylase associated protein
CHF17_RS06265	COG1115	amino acid carrier protein
CHF17_RS06270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHF17_RS06275	COG1380	Effector of murein hydrolase LrgA
CHF17_RS06280	COG1346	cytolysis
CHF17_RS06295	COG0539	negative regulation of cytoplasmic translation
CHF17_RS06315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHF17_RS06325	COG0187	DNA topoisomerase II activity
CHF17_RS06330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHF17_RS06335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHF17_RS06345	COG2755	lipolytic protein G-D-S-L family
CHF17_RS06345	COG1083	cytidylyl-transferase
CHF17_RS06360	COG2089	acid synthase
CHF17_RS06375	COG1216	Glycosyl transferase, family 2
CHF17_RS06375	COG1442	glycosyl transferase family 8
CHF17_RS06380	COG1442	glycosyl transferase family 8
CHF17_RS06380	COG1216	Glycosyl transferase, family 2
CHF17_RS06395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHF17_RS06400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHF17_RS06420	COG1316	TRANSCRIPTIONal
CHF17_RS06450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHF17_RS06485	COG3842	ATPase activity
CHF17_RS06500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CHF17_RS06505	COG3527	Alpha-acetolactate decarboxylase
CHF17_RS06510	COG0028	Belongs to the TPP enzyme family
CHF17_RS06515	COG0457	Tetratricopeptide repeat
CHF17_RS06520	COG0628	permease
CHF17_RS06530	COG1051	belongs to the nudix hydrolase family
CHF17_RS06535	COG5492	domain, Protein
CHF17_RS06540	COG1088	dTDP-glucose 4,6-dehydratase activity
CHF17_RS06550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CHF17_RS06555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHF17_RS06565	COG2384	SAM-dependent methyltransferase
CHF17_RS06590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHF17_RS06590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHF17_RS06595	COG0300	oxidoreductase activity
CHF17_RS06610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHF17_RS06615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHF17_RS06640	COG1573	uracil-dna glycosylase
CHF17_RS06645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHF17_RS06655	COG0584	glycerophosphoryl diester phosphodiesterase
CHF17_RS06675	COG0534	Mate efflux family protein
CHF17_RS06715	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHF17_RS06720	COG3344	reverse transcriptase
CHF17_RS06800	COG0515	serine threonine protein kinase
CHF17_RS06830	COG2040	homocysteine
CHF17_RS06835	COG0833	amino acid
CHF17_RS06875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHF17_RS06885	COG3425	synthase
CHF17_RS06900	COG1272	protein, Hemolysin III
CHF17_RS06945	COG0745	RESPONSE REGULATOR receiver
CHF17_RS06950	COG2357	RelA SpoT domain protein
CHF17_RS06955	COG1132	(ABC) transporter
CHF17_RS06970	COG0737	Belongs to the 5'-nucleotidase family
CHF17_RS06975	COG0242	peptide deformylase activity
CHF17_RS06980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHF17_RS06990	COG1132	(ABC) transporter
CHF17_RS07005	COG0488	(ABC) transporter
CHF17_RS07035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHF17_RS07035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHF17_RS07035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHF17_RS07040	COG1105	Belongs to the carbohydrate kinase PfkB family
CHF17_RS07045	COG1349	DNA-binding transcription factor activity
CHF17_RS07100	COG1837	Belongs to the UPF0109 family
CHF17_RS07105	COG0228	four-way junction DNA binding
CHF17_RS07110	COG0577	efflux transmembrane transporter activity
CHF17_RS07115	COG1136	(ABC) transporter
CHF17_RS07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHF17_RS07125	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHF17_RS07130	COG0505	Belongs to the CarA family
CHF17_RS07140	COG0564	pseudouridine synthase activity
CHF17_RS07150	COG0583	DNA-binding transcription factor activity
CHF17_RS07155	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHF17_RS07180	COG1104	cysteine desulfurase activity
CHF17_RS07190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHF17_RS07195	COG1442	glycosyl transferase family 8
CHF17_RS07215	COG0653	protein targeting
CHF17_RS07225	COG1073	alpha beta
CHF17_RS07265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHF17_RS07270	COG1368	sulfuric ester hydrolase activity
CHF17_RS07275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHF17_RS07285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHF17_RS07315	COG2244	polysaccharide biosynthetic process
CHF17_RS07320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHF17_RS07325	COG1120	ATPase activity
CHF17_RS07330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHF17_RS07335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHF17_RS07340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHF17_RS07355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHF17_RS07360	COG1253	flavin adenine dinucleotide binding
CHF17_RS07370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHF17_RS07375	COG1242	4 iron, 4 sulfur cluster binding
CHF17_RS07380	COG0671	phosphoesterase, PA-phosphatase related
CHF17_RS07385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHF17_RS07415	COG0681	Belongs to the peptidase S26 family
CHF17_RS07425	COG0297	glycogen (starch) synthase activity
CHF17_RS07465	COG3475	LICD family
CHF17_RS07480	COG0463	Glycosyl transferase, family 2
CHF17_RS07485	COG1215	transferase activity, transferring glycosyl groups
CHF17_RS07495	COG1091	dTDP-4-dehydrorhamnose reductase activity
CHF17_RS07500	COG2151	metal-sulfur cluster biosynthetic enzyme
CHF17_RS07505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHF17_RS07510	COG0358	DNA primase activity
CHF17_RS07515	COG1970	mechanosensitive ion channel activity
CHF17_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHF17_RS07540	COG0004	ammonium transporteR
CHF17_RS07550	COG1054	Belongs to the UPF0176 family
CHF17_RS07560	COG2271	Major facilitator Superfamily
CHF17_RS07565	COG0058	SHG alpha-glucan phosphorylase activity
CHF17_RS07570	COG1640	4-alpha-glucanotransferase
CHF17_RS07575	COG1609	Transcriptional regulator
CHF17_RS07585	COG1175	transmembrane transport
CHF17_RS07590	COG3833	ABC-type maltose transport systems, permease component
CHF17_RS07595	COG3104	oligopeptide transport
CHF17_RS07630	COG0765	amino acid transport
CHF17_RS07635	COG1126	abc transporter atp-binding protein
CHF17_RS07660	COG2309	aminopeptidase activity
CHF17_RS07680	COG1187	pseudouridine synthase activity
CHF17_RS07685	COG0656	L-ascorbic acid biosynthetic process
CHF17_RS07690	COG0778	Nitroreductase
CHF17_RS07695	COG0346	lactoylglutathione lyase activity
CHF17_RS07700	COG0463	Glycosyl transferase, family 2
CHF17_RS07705	COG1113	amino acid transport
CHF17_RS07710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHF17_RS07715	COG0557	exoribonuclease II activity
CHF17_RS07730	COG2814	Major facilitator Superfamily
CHF17_RS07740	COG1131	(ABC) transporter
CHF17_RS07750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHF17_RS07755	COG1396	sequence-specific DNA binding
CHF17_RS07810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHF17_RS07815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHF17_RS07840	COG1702	phosphate starvation-inducible protein PhoH
CHF17_RS07865	COG0233	cytoplasmic translational termination
CHF17_RS07880	COG0444	Belongs to the ABC transporter superfamily
CHF17_RS07885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHF17_RS07890	COG0601	transmembrane transport
CHF17_RS07895	COG0747	negative chemotaxis
CHF17_RS07900	COG0081	regulation of translation
CHF17_RS07920	COG1473	amidohydrolase
CHF17_RS07925	COG0583	DNA-binding transcription factor activity
CHF17_RS07940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHF17_RS07945	COG1674	ftsk spoiiie
CHF17_RS07950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHF17_RS07975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHF17_RS08005	COG0673	inositol 2-dehydrogenase activity
CHF17_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
CHF17_RS08070	COG1114	Component of the transport system for branched-chain amino acids
CHF17_RS08075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHF17_RS08075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHF17_RS08095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHF17_RS08105	COG0708	Exodeoxyribonuclease III
CHF17_RS08110	COG1393	Belongs to the ArsC family
CHF17_RS08115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHF17_RS08130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CHF17_RS08160	COG0470	DNA polymerase III
CHF17_RS08175	COG0517	IMP dehydrogenase activity
CHF17_RS08195	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHF17_RS08215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHF17_RS08220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHF17_RS08230	COG0531	amino acid
CHF17_RS08235	COG0569	domain protein
CHF17_RS08240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHF17_RS08250	COG1187	pseudouridine synthase activity
CHF17_RS08300	COG1827	regulation of RNA biosynthetic process
CHF17_RS08315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHF17_RS08320	COG1254	Belongs to the acylphosphatase family
CHF17_RS08330	COG0765	amino acid transport
CHF17_RS08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHF17_RS08350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHF17_RS08385	COG1484	DNA-dependent DNA replication
CHF17_RS08400	COG5002	protein histidine kinase activity
CHF17_RS08405	COG0745	RESPONSE REGULATOR receiver
CHF17_RS08420	COG1704	LemA family
CHF17_RS08425	COG0357	Ribosomal RNA small subunit methyltransferase G
CHF17_RS08430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHF17_RS08435	COG0569	domain protein
CHF17_RS08460	COG1114	Component of the transport system for branched-chain amino acids
CHF17_RS08465	COG1063	alcohol dehydrogenase
CHF17_RS08490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHF17_RS08495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHF17_RS08505	COG0217	transcriptional regulatory protein
CHF17_RS08540	COG2376	Dihydroxyacetone kinase
CHF17_RS08545	COG1309	transcriptional regulator
CHF17_RS08555	COG2376	Dihydroxyacetone kinase
CHF17_RS08560	COG1461	Dihydroxyacetone kinase
CHF17_RS08565	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHF17_RS08570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHF17_RS08595	COG2226	methyltransferase
CHF17_RS08600	COG0799	negative regulation of ribosome biogenesis
CHF17_RS08610	COG1713	HD superfamily hydrolase involved in NAD metabolism
CHF17_RS08615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHF17_RS08620	COG1534	Rna-binding protein
CHF17_RS08625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHF17_RS08630	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CHF17_RS08655	COG0574	Belongs to the PEP-utilizing enzyme family
CHF17_RS08655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHF17_RS08665	COG0517	IMP dehydrogenase activity
CHF17_RS08675	COG1335	isochorismatase
CHF17_RS08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHF17_RS08685	COG0436	Aminotransferase
CHF17_RS08690	COG0589	response to stress
CHF17_RS08695	COG0561	phosphatase activity
CHF17_RS08700	COG0252	asparaginase activity
CHF17_RS08710	COG4989	oxidoreductase activity
CHF17_RS08715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHF17_RS08720	COG3942	CHAP domain
CHF17_RS08720	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHF17_RS08730	COG0736	holo-[acyl-carrier-protein] synthase activity
CHF17_RS08735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHF17_RS08745	COG1482	cell wall glycoprotein biosynthetic process
CHF17_RS08750	COG1940	carbohydrate kinase activity
CHF17_RS08755	COG2190	(PTS) system
CHF17_RS08755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHF17_RS08755	COG1263	PTS System
CHF17_RS08760	COG1621	beta-fructofuranosidase activity
CHF17_RS08765	COG1609	Transcriptional regulator
CHF17_RS08770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHF17_RS08780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHF17_RS08830	COG2131	deaminase
CHF17_RS08835	COG0006	proline dipeptidase activity
CHF17_RS08845	COG2814	Major facilitator Superfamily
CHF17_RS08875	COG0629	single-stranded DNA binding
CHF17_RS08880	COG0360	Binds together with S18 to 16S ribosomal RNA
CHF17_RS08885	COG1194	a g-specific adenine glycosylase
CHF17_RS08895	COG3118	belongs to the thioredoxin family
CHF17_RS08925	COG0681	Belongs to the peptidase S26 family
CHF17_RS08930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHF17_RS08945	COG1882	Formate acetyltransferase
CHF17_RS08955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHF17_RS08970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHF17_RS08980	COG2814	Major facilitator Superfamily
CHF17_RS08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHF17_RS09000	COG0142	geranyltranstransferase activity
CHF17_RS09005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHF17_RS09010	COG4988	ABC transporter
CHF17_RS09015	COG1294	oxidase, subunit
CHF17_RS09020	COG1271	oxidase subunit
CHF17_RS09025	COG1252	NADH dehydrogenase
CHF17_RS09050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHF17_RS09055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHF17_RS09075	COG2081	HI0933 family
CHF17_RS09105	COG0456	acetyltransferase
CHF17_RS09110	COG1214	PFAM Peptidase M22, glycoprotease
CHF17_RS09125	COG3942	CHAP domain
CHF17_RS09130	COG0174	glutamine synthetase
CHF17_RS09135	COG0789	Transcriptional regulator
CHF17_RS09150	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CHF17_RS09175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHF17_RS09225	COG0084	hydrolase, TatD family'
CHF17_RS09250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CHF17_RS09255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHF17_RS09260	COG1696	Membrane protein involved in D-alanine export
CHF17_RS09280	COG0745	RESPONSE REGULATOR receiver
CHF17_RS09290	COG3314	Sporulation integral membrane protein YlbJ
CHF17_RS09305	COG3448	diguanylate cyclase activity
CHF17_RS09305	COG4175	Glycine betaine
CHF17_RS09315	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHF17_RS09335	COG1070	Carbohydrate kinase
CHF17_RS09345	COG3775	system Galactitol-specific IIC component
CHF17_RS09350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHF17_RS09360	COG1609	Transcriptional regulator
CHF17_RS09410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHF17_RS09445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHF17_RS09450	COG1428	Deoxynucleoside kinase
CHF17_RS09460	COG0542	response to heat
CHF17_RS09465	COG4463	regulation of RNA biosynthetic process
CHF17_RS09475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHF17_RS09485	COG0450	alkyl hydroperoxide reductase
CHF17_RS09500	COG0025	NhaP-type Na H and K H
CHF17_RS09510	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHF17_RS09515	COG3590	peptidase
CHF17_RS09545	COG1609	Transcriptional regulator
CHF17_RS09555	COG3716	PTS system mannose fructose sorbose family IID component
CHF17_RS09560	COG3715	PTS system
CHF17_RS09565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHF17_RS09570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CHF17_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
CHF17_RS09615	COG2176	DNA-directed DNA polymerase activity
CHF17_RS09620	COG1388	LysM domain
CHF17_RS09620	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHF17_RS09635	COG4589	Belongs to the CDS family
CHF17_RS09640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHF17_RS09645	COG1862	Preprotein translocase
CHF17_RS09665	COG3493	citrate carrier protein
CHF17_RS09670	COG3290	protein histidine kinase activity
CHF17_RS09675	COG4565	transcriptional regulatory protein
CHF17_RS09680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHF17_RS09690	COG3842	ATPase activity
CHF17_RS09765	COG1490	D-aminoacyl-tRNA deacylase activity
CHF17_RS09775	COG0737	Belongs to the 5'-nucleotidase family
CHF17_RS09785	COG1363	Peptidase, m42
CHF17_RS09800	COG2207	Transcriptional regulator
CHF17_RS09800	COG4753	response regulator
CHF17_RS09805	COG2972	Histidine kinase
CHF17_RS09810	COG3716	PTS system mannose fructose sorbose family IID component
CHF17_RS09815	COG3715	PTS system
CHF17_RS09845	COG1131	(ABC) transporter
CHF17_RS09860	COG3290	protein histidine kinase activity
CHF17_RS09865	COG3279	Response regulator of the LytR AlgR family
CHF17_RS09880	COG1263	PTS System
CHF17_RS09880	COG2190	(PTS) system
CHF17_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHF17_RS09885	COG5002	protein histidine kinase activity
CHF17_RS09890	COG0745	RESPONSE REGULATOR receiver
CHF17_RS09900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHF17_RS09905	COG0581	inorganic phosphate transmembrane transporter activity
CHF17_RS09910	COG0573	inorganic phosphate transmembrane transporter activity
CHF17_RS09925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHF17_RS09940	COG0789	Transcriptional regulator
CHF17_RS09965	COG0456	acetyltransferase
CHF17_RS09970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHF17_RS09985	COG0582	viral genome integration into host DNA
CHF17_RS10025	COG0433	COG0433 Predicted ATPase
CHF17_RS10045	COG4115	mRNA cleavage
CHF17_RS10080	COG3620	sequence-specific DNA binding
CHF17_RS10095	COG1674	ftsk spoiiie
CHF17_RS10140	COG1396	sequence-specific DNA binding
CHF17_RS10190	COG1914	H( )-stimulated, divalent metal cation uptake system
CHF17_RS10200	COG1131	(ABC) transporter
CHF17_RS10210	COG1994	Peptidase M50
CHF17_RS10215	COG0535	radical SAM domain protein
CHF17_RS10285	COG1131	(ABC) transporter
CHF17_RS10295	COG1396	sequence-specific DNA binding
CHF17_RS10310	COG1694	Mazg nucleotide pyrophosphohydrolase
CHF17_RS10325	COG2897	thiosulfate sulfurtransferase activity
CHF17_RS10345	COG0371	Dehydrogenase
CHF17_RS10355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CHF17_RS10355	COG0646	methionine synthase
CHF17_RS10360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHF17_RS10370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHF17_RS10385	COG2770	Histidine kinase
CHF17_RS10385	COG2205	protein histidine kinase activity
CHF17_RS10405	COG2814	Major facilitator Superfamily
CHF17_RS10410	COG4667	esterase of the alpha-beta hydrolase superfamily
CHF17_RS10415	COG1442	glycosyl transferase family 8
CHF17_RS10420	COG1442	glycosyl transferase family 8
CHF17_RS10445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHF17_RS10450	COG0564	pseudouridine synthase activity
CHF17_RS10470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHF17_RS10475	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CHF17_RS10495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHF17_RS10500	COG1116	anion transmembrane transporter activity
CHF17_RS10500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHF17_RS10510	COG0561	phosphatase activity
CHF17_RS10515	COG2514	catechol 2,3-dioxygenase activity
CHF17_RS10525	COG0602	queuosine metabolic process
CHF17_RS10545	COG1328	CTP reductase activity
CHF17_RS10545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHF17_RS10565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHF17_RS10575	COG1393	Belongs to the ArsC family
CHF17_RS10580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHF17_RS10585	COG1546	Belongs to the CinA family
CHF17_RS10585	COG1058	Belongs to the CinA family
CHF17_RS10590	COG2818	Glycosylase
CHF17_RS10630	COG0018	arginyl-trna synthetase
CHF17_RS10640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHF17_RS10645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHF17_RS10650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHF17_RS10655	COG0124	histidyl-tRNA synthetase
CHF17_RS10665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHF17_RS10720	COG4974	Belongs to the 'phage' integrase family
CHF17_RS10730	COG0745	RESPONSE REGULATOR receiver
CHF17_RS10735	COG5002	protein histidine kinase activity
CHF17_RS10740	COG1288	antiporter activity
CHF17_RS10750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHF17_RS10755	COG3852	Histidine kinase
CHF17_RS10760	COG0784	Response regulator, receiver
CHF17_RS10765	COG0517	IMP dehydrogenase activity
CHF17_RS10765	COG1125	glycine betaine transport
CHF17_RS10770	COG1174	glycine betaine transport
CHF17_RS10775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CHF17_RS10775	COG0392	lysyltransferase activity
CHF17_RS10785	COG3759	membrane
CHF17_RS10905	COG3645	SOS response
CHF17_RS10910	COG0582	viral genome integration into host DNA
CHF17_RS10925	COG0305	Participates in initiation and elongation during chromosome replication
CHF17_RS10940	COG0445	tRNA wobble uridine modification
CHF17_RS10945	COG2095	MarC family integral membrane protein
CHF17_RS10950	COG0482	sulfurtransferase activity
CHF17_RS10955	COG1760	l-serine dehydratase
CHF17_RS10960	COG1760	l-serine dehydratase
CHF17_RS10965	COG0741	lytic transglycosylase activity
CHF17_RS10990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHF17_RS10995	COG0612	Peptidase, M16
CHF17_RS11000	COG0612	Peptidase, M16
CHF17_RS11005	COG2501	S4 domain
CHF17_RS11025	COG0517	IMP dehydrogenase activity
CHF17_RS11025	COG0516	GMP reductase activity
CHF17_RS11035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHF17_RS11080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHF17_RS11085	COG0488	(ABC) transporter
CHF17_RS11090	COG4485	Bacterial membrane protein, YfhO
CHF17_RS11110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHF17_RS11115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHF17_RS11120	COG1475	DNA binding