locus-tag	class	description
SAK_RS00010	COG0592	DNA-directed DNA polymerase activity
SAK_RS00015	COG1597	lipid kinase activity
SAK_RS00025	COG0012	GTP binding
SAK_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SAK_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAK_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAK_RS00255	COG0436	Aminotransferase
SAK_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAK_RS00285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAK_RS00300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SAK_RS00335	COG1175	transmembrane transport
SAK_RS00340	COG0395	ABC-type sugar transport system, permease component
SAK_RS00355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAK_RS00365	COG3458	cephalosporin-C deacetylase activity
SAK_RS00380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAK_RS00395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAK_RS00410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAK_RS00420	COG2755	lipolytic protein G-D-S-L family
SAK_RS00420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAK_RS00425	COG1012	belongs to the aldehyde dehydrogenase family
SAK_RS00425	COG1454	alcohol dehydrogenase
SAK_RS00430	COG1064	alcohol dehydrogenase
SAK_RS00440	COG0534	Mate efflux family protein
SAK_RS00550	COG0201	protein transport
SAK_RS00565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAK_RS00710	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAK_RS00725	COG0443	Heat shock 70 kDa protein
SAK_RS00735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAK_RS00745	COG0351	phosphomethylpyrimidine kinase
SAK_RS00750	COG4720	Psort location CytoplasmicMembrane, score
SAK_RS00760	COG0668	transmembrane transport
SAK_RS00790	COG0756	dUTP diphosphatase activity
SAK_RS00805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAK_RS00820	COG1879	ABC-type sugar transport system periplasmic component
SAK_RS00825	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAK_RS00840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAK_RS00845	COG1609	Transcriptional regulator
SAK_RS00850	COG0577	efflux transmembrane transporter activity
SAK_RS00855	COG1136	(ABC) transporter
SAK_RS00860	COG0745	RESPONSE REGULATOR receiver
SAK_RS00865	COG5002	protein histidine kinase activity
SAK_RS00880	COG0191	fructose-bisphosphate aldolase activity
SAK_RS00900	COG1461	Dihydroxyacetone kinase
SAK_RS00930	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAK_RS00935	COG5002	protein histidine kinase activity
SAK_RS00940	COG0745	RESPONSE REGULATOR receiver
SAK_RS00955	COG1126	abc transporter atp-binding protein
SAK_RS00960	COG0765	amino acid transport
SAK_RS00980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAK_RS00990	COG0719	Fe-S assembly protein
SAK_RS00995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAK_RS01005	COG0719	Fe-S assembly protein
SAK_RS01010	COG1686	Belongs to the peptidase S11 family
SAK_RS01015	COG1686	Belongs to the peptidase S11 family
SAK_RS01020	COG4166	transmembrane transport
SAK_RS01025	COG0601	transmembrane transport
SAK_RS01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAK_RS01035	COG0444	Belongs to the ABC transporter superfamily
SAK_RS01040	COG4608	Belongs to the ABC transporter superfamily
SAK_RS01080	COG1121	(ABC) transporter
SAK_RS01085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAK_RS01100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAK_RS01100	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAK_RS01120	COG1459	type II secretion system
SAK_RS01175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAK_RS01180	COG1363	Peptidase, m42
SAK_RS01195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAK_RS01200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAK_RS01215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAK_RS01235	COG1346	cytolysis
SAK_RS01245	COG0601	transmembrane transport
SAK_RS01250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAK_RS01255	COG1122	ATPase activity
SAK_RS01265	COG1263	PTS System
SAK_RS01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAK_RS01270	COG0366	Alpha amylase catalytic
SAK_RS01275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAK_RS01290	COG3959	Transketolase, thiamine diphosphate binding domain
SAK_RS01295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SAK_RS01300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAK_RS01320	COG1045	serine acetyltransferase
SAK_RS01335	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAK_RS01355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAK_RS01365	COG4974	Belongs to the 'phage' integrase family
SAK_RS01470	COG1396	sequence-specific DNA binding
SAK_RS01475	COG2814	Major facilitator Superfamily
SAK_RS01485	COG1732	Glycine betaine
SAK_RS01620	COG0519	Catalyzes the synthesis of GMP from XMP
SAK_RS01665	COG1695	Transcriptional regulator
SAK_RS01680	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAK_RS01720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAK_RS01725	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAK_RS01745	COG1131	(ABC) transporter
SAK_RS01755	COG1263	PTS System
SAK_RS01755	COG2190	(PTS) system
SAK_RS01755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAK_RS01760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAK_RS01780	COG0768	penicillin binding
SAK_RS01790	COG0513	Belongs to the DEAD box helicase family
SAK_RS01805	COG1126	abc transporter atp-binding protein
SAK_RS01815	COG0492	ferredoxin-NADP+ reductase activity
SAK_RS01820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAK_RS01830	COG3579	cysteine-type endopeptidase activity
SAK_RS01835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAK_RS01855	COG0116	Belongs to the methyltransferase superfamily
SAK_RS01865	COG1854	S-ribosylhomocysteine lyase activity
SAK_RS01870	COG4372	Transposase
SAK_RS01870	COG1418	mRNA catabolic process
SAK_RS01875	COG1131	(ABC) transporter
SAK_RS01885	COG4585	Histidine kinase
SAK_RS01890	COG2197	response regulator
SAK_RS01900	COG0194	GDP metabolic process
SAK_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAK_RS01915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAK_RS01920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAK_RS01920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAK_RS01930	COG2815	serine threonine protein kinase
SAK_RS01930	COG0515	serine threonine protein kinase
SAK_RS01940	COG4585	Histidine kinase
SAK_RS01945	COG2197	response regulator
SAK_RS01955	COG1098	S1 RNA binding domain
SAK_RS01960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAK_RS01965	COG1349	DNA-binding transcription factor activity
SAK_RS01975	COG1447	Phosphotransferase system cellobiose-specific component IIA
SAK_RS01985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAK_RS01990	COG1882	Formate acetyltransferase
SAK_RS02010	COG1739	Uncharacterized protein family UPF0029
SAK_RS02015	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAK_RS02020	COG1040	competence protein
SAK_RS02055	COG0527	aspartate kinase activity
SAK_RS02060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAK_RS02065	COG1024	Enoyl-CoA hydratase
SAK_RS02075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAK_RS02085	COG2070	2-Nitropropane dioxygenase
SAK_RS02090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SAK_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
SAK_RS02100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAK_RS02115	COG0439	Biotin carboxylase
SAK_RS02135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAK_RS02150	COG3716	PTS system mannose fructose sorbose family IID component
SAK_RS02155	COG3715	PTS system
SAK_RS02165	COG0561	phosphatase activity
SAK_RS02180	COG2252	PERMEase
SAK_RS02185	COG0802	atpase or kinase
SAK_RS02195	COG1316	TRANSCRIPTIONal
SAK_RS02205	COG0537	adenosine 5'-monophosphoramidase activity
SAK_RS02220	COG1131	(ABC) transporter
SAK_RS02225	COG4473	ABC transporter
SAK_RS02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAK_RS02250	COG0195	Participates in both transcription termination and antitermination
SAK_RS02255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAK_RS02265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SAK_RS02270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAK_RS02295	COG2860	membrane
SAK_RS02305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAK_RS02305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAK_RS02310	COG1832	CoA-binding protein
SAK_RS02330	COG5002	protein histidine kinase activity
SAK_RS02350	COG1268	BioY protein
SAK_RS02355	COG1234	tRNA 3'-trailer cleavage
SAK_RS02370	COG0166	Belongs to the GPI family
SAK_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAK_RS02380	COG0705	Rhomboid family
SAK_RS02380	COG0457	Tetratricopeptide repeat
SAK_RS02385	COG1744	ABC transporter substrate-binding protein PnrA-like
SAK_RS02390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAK_RS02405	COG0706	membrane insertase activity
SAK_RS02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAK_RS02475	COG2153	protein acetylation
SAK_RS02485	COG1216	Glycosyl transferase, family 2
SAK_RS02485	COG1442	glycosyl transferase family 8
SAK_RS02520	COG2801	Transposase and inactivated derivatives
SAK_RS02530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAK_RS02540	COG0789	Transcriptional regulator
SAK_RS02550	COG0656	L-ascorbic acid biosynthetic process
SAK_RS02595	COG2226	methyltransferase
SAK_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAK_RS02610	COG3414	Phosphotransferase system galactitol-specific IIB component
SAK_RS02615	COG3775	system Galactitol-specific IIC component
SAK_RS02620	COG0235	Class ii aldolase
SAK_RS02630	COG3775	system Galactitol-specific IIC component
SAK_RS02635	COG3414	Phosphotransferase system galactitol-specific IIB component
SAK_RS02640	COG2207	Transcriptional regulator
SAK_RS02650	COG1175	transmembrane transport
SAK_RS02655	COG0395	ABC-type sugar transport system, permease component
SAK_RS02675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAK_RS02680	COG2017	converts alpha-aldose to the beta-anomer
SAK_RS02730	COG0673	inositol 2-dehydrogenase activity
SAK_RS02740	COG2315	Protein conserved in bacteria
SAK_RS02755	COG0742	ribosomal rna small subunit methyltransferase
SAK_RS02770	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAK_RS02775	COG0737	Belongs to the 5'-nucleotidase family
SAK_RS02780	COG4470	Protein conserved in bacteria
SAK_RS02795	COG1132	(ABC) transporter
SAK_RS02800	COG1132	(ABC) transporter
SAK_RS02805	COG0512	Glutamine amidotransferase of anthranilate synthase
SAK_RS02815	COG1268	BioY protein
SAK_RS02830	COG0183	Belongs to the thiolase family
SAK_RS02840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAK_RS02855	COG1940	carbohydrate kinase activity
SAK_RS02860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAK_RS02865	COG1217	gtp-binding protein TYPA
SAK_RS02900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAK_RS02910	COG0762	integral membrane protein
SAK_RS02915	COG2302	S4 RNA-binding domain
SAK_RS02920	COG3599	regulation of cell shape
SAK_RS02935	COG0494	nUDIX hydrolase
SAK_RS02940	COG0542	response to heat
SAK_RS02945	COG4703	Protein of unknown function (DUF1797)
SAK_RS02950	COG0765	amino acid transport
SAK_RS02955	COG1126	abc transporter atp-binding protein
SAK_RS02960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAK_RS02970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAK_RS02980	COG1722	exodeoxyribonuclease VII activity
SAK_RS02990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SAK_RS02995	COG1438	arginine binding
SAK_RS03000	COG0497	DNA recombination
SAK_RS03005	COG1307	EDD domain protein, DegV family
SAK_RS03010	COG2755	lipolytic protein G-D-S-L family
SAK_RS03025	COG0582	viral genome integration into host DNA
SAK_RS03030	COG2314	TM2 domain
SAK_RS03310	COG1078	dGTPase activity
SAK_RS03335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAK_RS03345	COG2884	Cell division ATP-binding protein ftsE
SAK_RS03350	COG2177	Part of the ABC transporter FtsEX involved in
SAK_RS03375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAK_RS03375	COG1199	ATP-dependent helicase activity
SAK_RS03380	COG0436	Aminotransferase
SAK_RS03385	COG0017	Asparaginyl-tRNA synthetase
SAK_RS03405	COG1660	Displays ATPase and GTPase activities
SAK_RS03435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAK_RS03445	COG0716	FMN binding
SAK_RS03450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAK_RS03450	COG1605	Chorismate mutase
SAK_RS03455	COG0038	chloride channel
SAK_RS03460	COG0335	large ribosomal subunit rRNA binding
SAK_RS03495	COG1136	(ABC) transporter
SAK_RS03510	COG5002	protein histidine kinase activity
SAK_RS03530	COG0772	Belongs to the SEDS family
SAK_RS03550	COG0560	Phosphoserine phosphatase
SAK_RS03565	COG0148	phosphopyruvate hydratase activity
SAK_RS03585	COG1316	TRANSCRIPTIONal
SAK_RS03625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAK_RS03625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAK_RS03665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAK_RS03685	COG0270	DNA (cytosine-5-)-methyltransferase activity
SAK_RS03725	COG4695	Portal protein
SAK_RS03730	COG0740	serine-type endopeptidase activity
SAK_RS03800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAK_RS03825	COG3700	Belongs to the class B bacterial acid phosphatase family
SAK_RS03920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAK_RS03925	COG4555	ABC transporter
SAK_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
SAK_RS03955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAK_RS03960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAK_RS03980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SAK_RS03985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAK_RS04005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SAK_RS04005	COG3064	Membrane
SAK_RS04020	COG3590	peptidase
SAK_RS04025	COG3590	peptidase
SAK_RS04065	COG1136	(ABC) transporter
SAK_RS04080	COG0586	Pfam SNARE associated Golgi protein
SAK_RS04085	COG4619	ABC transporter
SAK_RS04090	COG0390	transport system, permease component
SAK_RS04100	COG0583	DNA-binding transcription factor activity
SAK_RS04110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAK_RS04115	COG2211	Major facilitator Superfamily
SAK_RS04125	COG3250	beta-galactosidase activity
SAK_RS04130	COG2186	Transcriptional regulator
SAK_RS04135	COG0800	Aldolase
SAK_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
SAK_RS04170	COG1609	Transcriptional regulator
SAK_RS04185	COG0438	transferase activity, transferring glycosyl groups
SAK_RS04210	COG0765	amino acid transport
SAK_RS04215	COG0765	amino acid transport
SAK_RS04220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAK_RS04225	COG1126	abc transporter atp-binding protein
SAK_RS04230	COG0745	RESPONSE REGULATOR receiver
SAK_RS04235	COG5002	protein histidine kinase activity
SAK_RS04240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAK_RS04245	COG2832	Protein of unknown function (DUF454)
SAK_RS04255	COG1196	nuclear chromosome segregation
SAK_RS04260	COG0561	phosphatase activity
SAK_RS04265	COG0561	phosphatase activity
SAK_RS04270	COG0552	protein localization to endoplasmic reticulum
SAK_RS04275	COG3689	TIGRFAM TIGR03943 family protein
SAK_RS04280	COG0701	Predicted permease
SAK_RS04295	COG2183	response to ionizing radiation
SAK_RS04300	COG3091	SprT-like family
SAK_RS04305	COG1983	PspC domain protein
SAK_RS04340	COG0826	peptidase U32
SAK_RS04345	COG4443	Transcriptional Coactivator p15 (PC4)
SAK_RS04355	COG1914	H( )-stimulated, divalent metal cation uptake system
SAK_RS04370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAK_RS04370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAK_RS04395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAK_RS04420	COG1164	Oligoendopeptidase f
SAK_RS04430	COG0772	Belongs to the SEDS family
SAK_RS04450	COG0768	penicillin binding
SAK_RS04465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAK_RS04470	COG2223	nitrite transmembrane transporter activity
SAK_RS04495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAK_RS04500	COG2011	ABC-type metal ion transport system permease component
SAK_RS04505	COG1464	Belongs to the NlpA lipoprotein family
SAK_RS04510	COG0513	Belongs to the DEAD box helicase family
SAK_RS04520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAK_RS04525	COG0204	Acyl-transferase
SAK_RS04530	COG1596	polysaccharide export
SAK_RS04530	COG1555	photosystem II stabilization
SAK_RS04535	COG0658	competence protein
SAK_RS04535	COG2333	competence protein COMEC
SAK_RS04540	COG0561	phosphatase activity
SAK_RS04545	COG1609	Transcriptional regulator
SAK_RS04550	COG0657	acetylesterase activity
SAK_RS04555	COG2226	methyltransferase
SAK_RS04565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAK_RS04570	COG3711	transcriptional antiterminator
SAK_RS04575	COG2190	(PTS) system
SAK_RS04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAK_RS04575	COG1263	PTS System
SAK_RS04585	COG3835	regulator
SAK_RS04590	COG1929	Belongs to the glycerate kinase type-1 family
SAK_RS04595	COG2610	gluconate transmembrane transporter activity
SAK_RS04605	COG1846	Transcriptional regulator
SAK_RS04620	COG0363	glucosamine-6-phosphate deaminase activity
SAK_RS04625	COG0435	Glutathione S-transferase
SAK_RS04630	COG1187	pseudouridine synthase activity
SAK_RS04650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAK_RS04655	COG4122	O-methyltransferase activity
SAK_RS04665	COG4894	glucomannan catabolic process
SAK_RS04680	COG1442	glycosyl transferase family 8
SAK_RS04690	COG1476	TRANSCRIPTIONal
SAK_RS04710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAK_RS04715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAK_RS04720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAK_RS04735	COG1012	belongs to the aldehyde dehydrogenase family
SAK_RS04740	COG0726	polysaccharide deacetylase
SAK_RS04755	COG1956	GAF domain-containing protein
SAK_RS04760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAK_RS04770	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SAK_RS04770	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SAK_RS04800	COG4721	ABC-type cobalt transport system, permease component
SAK_RS04805	COG1122	ATPase activity
SAK_RS04815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAK_RS04845	COG4109	DRTGG domain
SAK_RS04850	COG0024	Methionine aminopeptidase
SAK_RS04860	COG2246	polysaccharide biosynthetic process
SAK_RS04865	COG4708	membrane
SAK_RS04875	COG1597	lipid kinase activity
SAK_RS04880	COG1523	belongs to the glycosyl hydrolase 13 family
SAK_RS04895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SAK_RS04980	COG2321	neutral zinc metallopeptidase
SAK_RS05005	COG0488	(ABC) transporter
SAK_RS05010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAK_RS05015	COG0022	dehydrogenase e1 component
SAK_RS05015	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAK_RS05020	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAK_RS05030	COG0095	Lipoate-protein ligase
SAK_RS05035	COG3442	glutamine amidotransferase
SAK_RS05040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAK_RS05045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAK_RS05070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAK_RS05080	COG0647	UMP catabolic process
SAK_RS05090	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SAK_RS05095	COG1518	maintenance of DNA repeat elements
SAK_RS05100	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SAK_RS05120	COG0481	GTPase activity
SAK_RS05130	COG1418	mRNA catabolic process
SAK_RS05135	COG0456	acetyltransferase
SAK_RS05145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAK_RS05170	COG1131	(ABC) transporter
SAK_RS05175	COG1725	Transcriptional regulator
SAK_RS05185	COG0205	6-phosphofructokinase activity
SAK_RS05190	COG0469	pyruvate kinase activity
SAK_RS05200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAK_RS05205	COG2824	Alkylphosphonate utilization operon protein PhnA
SAK_RS05210	COG0765	amino acid transport
SAK_RS05215	COG1126	abc transporter atp-binding protein
SAK_RS05230	COG1072	(Pantothenic acid kinase))
SAK_RS05235	COG2813	Specifically methylates the guanine in position
SAK_RS05245	COG1744	ABC transporter substrate-binding protein PnrA-like
SAK_RS05250	COG3845	ABC transporter
SAK_RS05255	COG4603	Belongs to the binding-protein-dependent transport system permease family
SAK_RS05260	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAK_RS05280	COG3764	Sortase (surface protein transpeptidase)
SAK_RS05285	COG0346	lactoylglutathione lyase activity
SAK_RS05315	COG2188	Transcriptional regulator
SAK_RS05330	COG1464	Belongs to the NlpA lipoprotein family
SAK_RS05345	COG1136	(ABC) transporter
SAK_RS05355	COG0745	RESPONSE REGULATOR receiver
SAK_RS05360	COG5002	protein histidine kinase activity
SAK_RS05365	COG4974	Belongs to the 'phage' integrase family
SAK_RS05370	COG4166	transmembrane transport
SAK_RS05385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAK_RS05390	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SAK_RS05395	COG5002	protein histidine kinase activity
SAK_RS05400	COG0745	RESPONSE REGULATOR receiver
SAK_RS05410	COG0704	Plays a role in the regulation of phosphate uptake
SAK_RS05415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAK_RS05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAK_RS05425	COG0581	inorganic phosphate transmembrane transporter activity
SAK_RS05430	COG0573	inorganic phosphate transmembrane transporter activity
SAK_RS05440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SAK_RS05440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAK_RS05445	COG0483	inositol monophosphate 1-phosphatase activity
SAK_RS05460	COG0196	riboflavin kinase activity
SAK_RS05465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAK_RS05495	COG1136	(ABC) transporter
SAK_RS05500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAK_RS05505	COG0758	DNA mediated transformation
SAK_RS05510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAK_RS05515	COG4604	ABC transporter, ATP-binding protein
SAK_RS05520	COG4605	iron ion homeostasis
SAK_RS05525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAK_RS05530	COG0110	maltose O-acetyltransferase activity
SAK_RS05540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAK_RS05545	COG1376	ErfK ybiS ycfS ynhG family protein
SAK_RS05550	COG1966	Carbon starvation protein
SAK_RS05555	COG3279	Response regulator of the LytR AlgR family
SAK_RS05560	COG3275	phosphorelay sensor kinase activity
SAK_RS05665	COG0505	Belongs to the CarA family
SAK_RS05675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAK_RS05695	COG0488	(ABC) transporter
SAK_RS05705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAK_RS05715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SAK_RS05755	COG0095	Lipoate-protein ligase
SAK_RS05765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAK_RS05770	COG4684	Psort location CytoplasmicMembrane, score
SAK_RS05775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAK_RS05785	COG1132	(ABC) transporter
SAK_RS05815	COG2890	protein-(glutamine-N5) methyltransferase activity
SAK_RS05830	COG1942	4-Oxalocrotonate Tautomerase
SAK_RS05845	COG1053	succinate dehydrogenase
SAK_RS05845	COG0431	NADPH-dependent FMN reductase
SAK_RS05845	COG3976	FMN-binding domain protein
SAK_RS05855	COG2233	PERMEase
SAK_RS05870	COG0477	Major facilitator Superfamily
SAK_RS05885	COG4221	oxidoreductase activity
SAK_RS05890	COG0280	phosphate acetyltransferase
SAK_RS05895	COG0564	pseudouridine synthase activity
SAK_RS05900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SAK_RS05905	COG2357	RelA SpoT domain protein
SAK_RS05920	COG1104	cysteine desulfurase activity
SAK_RS05940	COG0628	permease
SAK_RS05945	COG2723	6-phospho-beta-galactosidase activity
SAK_RS05955	COG0561	phosphatase activity
SAK_RS05965	COG0038	chloride channel
SAK_RS05975	COG1177	transmembrane transport
SAK_RS05980	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAK_RS05990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAK_RS05995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAK_RS06015	COG0285	dihydrofolate synthase activity
SAK_RS06020	COG2962	Rard protein
SAK_RS06035	COG0726	polysaccharide deacetylase
SAK_RS06040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAK_RS06055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAK_RS06060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAK_RS06065	COG1012	belongs to the aldehyde dehydrogenase family
SAK_RS06150	COG2261	transglycosylase associated protein
SAK_RS06175	COG1115	amino acid carrier protein
SAK_RS06180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAK_RS06190	COG1346	cytolysis
SAK_RS06205	COG0539	negative regulation of cytoplasmic translation
SAK_RS06225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAK_RS06235	COG0187	DNA topoisomerase II activity
SAK_RS06240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SAK_RS06245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAK_RS06255	COG1083	cytidylyl-transferase
SAK_RS06255	COG2755	lipolytic protein G-D-S-L family
SAK_RS06270	COG2089	acid synthase
SAK_RS06285	COG1442	glycosyl transferase family 8
SAK_RS06285	COG1216	Glycosyl transferase, family 2
SAK_RS06290	COG1216	Glycosyl transferase, family 2
SAK_RS06290	COG1442	glycosyl transferase family 8
SAK_RS06305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAK_RS06330	COG1316	TRANSCRIPTIONal
SAK_RS06355	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAK_RS06390	COG3842	ATPase activity
SAK_RS06405	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAK_RS06410	COG3527	Alpha-acetolactate decarboxylase
SAK_RS06415	COG0028	Belongs to the TPP enzyme family
SAK_RS06420	COG0457	Tetratricopeptide repeat
SAK_RS06425	COG0628	permease
SAK_RS06435	COG1051	belongs to the nudix hydrolase family
SAK_RS06440	COG5492	domain, Protein
SAK_RS06445	COG1088	dTDP-glucose 4,6-dehydratase activity
SAK_RS06455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SAK_RS06460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAK_RS06470	COG2384	SAM-dependent methyltransferase
SAK_RS06490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAK_RS06490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAK_RS06495	COG0300	oxidoreductase activity
SAK_RS06510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAK_RS06530	COG1523	belongs to the glycosyl hydrolase 13 family
SAK_RS06540	COG1573	uracil-dna glycosylase
SAK_RS06545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAK_RS06555	COG0584	glycerophosphoryl diester phosphodiesterase
SAK_RS06570	COG0534	Mate efflux family protein
SAK_RS06605	COG2801	Transposase and inactivated derivatives
SAK_RS06625	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAK_RS06650	COG2176	DNA-directed DNA polymerase activity
SAK_RS06660	COG4974	Belongs to the 'phage' integrase family
SAK_RS06690	COG1674	ftsk spoiiie
SAK_RS06730	COG2040	homocysteine
SAK_RS06735	COG0833	amino acid
SAK_RS06770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAK_RS06780	COG3425	synthase
SAK_RS06795	COG1272	protein, Hemolysin III
SAK_RS06840	COG0745	RESPONSE REGULATOR receiver
SAK_RS06845	COG2357	RelA SpoT domain protein
SAK_RS06850	COG1132	(ABC) transporter
SAK_RS06865	COG0737	Belongs to the 5'-nucleotidase family
SAK_RS06870	COG0242	peptide deformylase activity
SAK_RS06875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAK_RS06885	COG1132	(ABC) transporter
SAK_RS06900	COG0488	(ABC) transporter
SAK_RS06930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAK_RS06930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAK_RS06930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAK_RS06935	COG1105	Belongs to the carbohydrate kinase PfkB family
SAK_RS06940	COG1349	DNA-binding transcription factor activity
SAK_RS06945	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAK_RS06945	COG1388	LysM domain
SAK_RS06995	COG1837	Belongs to the UPF0109 family
SAK_RS07000	COG0228	four-way junction DNA binding
SAK_RS07005	COG0577	efflux transmembrane transporter activity
SAK_RS07010	COG1136	(ABC) transporter
SAK_RS07015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SAK_RS07025	COG0505	Belongs to the CarA family
SAK_RS07035	COG0564	pseudouridine synthase activity
SAK_RS07045	COG0583	DNA-binding transcription factor activity
SAK_RS07050	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SAK_RS07075	COG1104	cysteine desulfurase activity
SAK_RS07085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAK_RS07110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAK_RS07115	COG1368	sulfuric ester hydrolase activity
SAK_RS07120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAK_RS07130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAK_RS07160	COG2244	polysaccharide biosynthetic process
SAK_RS07170	COG1120	ATPase activity
SAK_RS07175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAK_RS07180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAK_RS07185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAK_RS07200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAK_RS07205	COG1253	flavin adenine dinucleotide binding
SAK_RS07210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAK_RS07215	COG1242	4 iron, 4 sulfur cluster binding
SAK_RS07220	COG0671	phosphoesterase, PA-phosphatase related
SAK_RS07225	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAK_RS07255	COG0681	Belongs to the peptidase S26 family
SAK_RS07265	COG0297	glycogen (starch) synthase activity
SAK_RS07305	COG3475	LICD family
SAK_RS07320	COG0463	Glycosyl transferase, family 2
SAK_RS07325	COG1215	transferase activity, transferring glycosyl groups
SAK_RS07335	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAK_RS07340	COG2151	metal-sulfur cluster biosynthetic enzyme
SAK_RS07345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAK_RS07350	COG0358	DNA primase activity
SAK_RS07355	COG1970	mechanosensitive ion channel activity
SAK_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAK_RS07375	COG0004	ammonium transporteR
SAK_RS07385	COG1054	Belongs to the UPF0176 family
SAK_RS07395	COG2271	Major facilitator Superfamily
SAK_RS07400	COG0058	SHG alpha-glucan phosphorylase activity
SAK_RS07405	COG1640	4-alpha-glucanotransferase
SAK_RS07410	COG1609	Transcriptional regulator
SAK_RS07420	COG1175	transmembrane transport
SAK_RS07425	COG3833	ABC-type maltose transport systems, permease component
SAK_RS07430	COG3104	oligopeptide transport
SAK_RS07450	COG0438	transferase activity, transferring glycosyl groups
SAK_RS07480	COG1442	glycosyl transferase family 8
SAK_RS07485	COG1216	Glycosyl transferase, family 2
SAK_RS07485	COG1442	glycosyl transferase family 8
SAK_RS07490	COG1442	glycosyl transferase family 8
SAK_RS07495	COG1442	glycosyl transferase family 8
SAK_RS07495	COG1216	Glycosyl transferase, family 2
SAK_RS07500	COG1442	glycosyl transferase family 8
SAK_RS07535	COG0765	amino acid transport
SAK_RS07540	COG1126	abc transporter atp-binding protein
SAK_RS07565	COG2309	aminopeptidase activity
SAK_RS07575	COG0154	amidase activity
SAK_RS07580	COG1187	pseudouridine synthase activity
SAK_RS07585	COG0656	L-ascorbic acid biosynthetic process
SAK_RS07590	COG0778	Nitroreductase
SAK_RS07595	COG0346	lactoylglutathione lyase activity
SAK_RS07600	COG0463	Glycosyl transferase, family 2
SAK_RS07605	COG1113	amino acid transport
SAK_RS07610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAK_RS07615	COG0557	exoribonuclease II activity
SAK_RS07625	COG2814	Major facilitator Superfamily
SAK_RS07635	COG1131	(ABC) transporter
SAK_RS07645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAK_RS07650	COG1396	sequence-specific DNA binding
SAK_RS07690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SAK_RS07695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAK_RS07715	COG1702	phosphate starvation-inducible protein PhoH
SAK_RS07740	COG0233	cytoplasmic translational termination
SAK_RS07755	COG0444	Belongs to the ABC transporter superfamily
SAK_RS07760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAK_RS07765	COG0601	transmembrane transport
SAK_RS07770	COG0747	negative chemotaxis
SAK_RS07775	COG0081	regulation of translation
SAK_RS07795	COG1473	amidohydrolase
SAK_RS07800	COG0583	DNA-binding transcription factor activity
SAK_RS07815	COG2801	Transposase and inactivated derivatives
SAK_RS07820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAK_RS07825	COG1674	ftsk spoiiie
SAK_RS07830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAK_RS07855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAK_RS07885	COG0673	inositol 2-dehydrogenase activity
SAK_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
SAK_RS07945	COG1114	Component of the transport system for branched-chain amino acids
SAK_RS07950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAK_RS07950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAK_RS07965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAK_RS07975	COG0708	Exodeoxyribonuclease III
SAK_RS07980	COG1393	Belongs to the ArsC family
SAK_RS07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAK_RS07990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAK_RS08020	COG0470	DNA polymerase III
SAK_RS08035	COG0517	IMP dehydrogenase activity
SAK_RS08055	COG0559	Belongs to the binding-protein-dependent transport system permease family
SAK_RS08075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAK_RS08080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAK_RS08090	COG0531	amino acid
SAK_RS08095	COG0569	domain protein
SAK_RS08100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAK_RS08110	COG1187	pseudouridine synthase activity
SAK_RS08160	COG1827	regulation of RNA biosynthetic process
SAK_RS08175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAK_RS08180	COG1254	Belongs to the acylphosphatase family
SAK_RS08190	COG0765	amino acid transport
SAK_RS08195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAK_RS08210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SAK_RS08240	COG1484	DNA-dependent DNA replication
SAK_RS08255	COG5002	protein histidine kinase activity
SAK_RS08260	COG0745	RESPONSE REGULATOR receiver
SAK_RS08275	COG1704	LemA family
SAK_RS08285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAK_RS08290	COG0569	domain protein
SAK_RS08320	COG1063	alcohol dehydrogenase
SAK_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAK_RS08350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAK_RS08355	COG0217	transcriptional regulatory protein
SAK_RS08360	COG2376	Dihydroxyacetone kinase
SAK_RS08365	COG1309	transcriptional regulator
SAK_RS08370	COG2376	Dihydroxyacetone kinase
SAK_RS08375	COG1461	Dihydroxyacetone kinase
SAK_RS08380	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAK_RS08385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAK_RS08395	COG0789	Transcriptional regulator
SAK_RS08410	COG2226	methyltransferase
SAK_RS08415	COG0799	negative regulation of ribosome biogenesis
SAK_RS08425	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAK_RS08430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAK_RS08435	COG1534	Rna-binding protein
SAK_RS08440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAK_RS08445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAK_RS08470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAK_RS08470	COG0574	Belongs to the PEP-utilizing enzyme family
SAK_RS08480	COG0517	IMP dehydrogenase activity
SAK_RS08490	COG1335	isochorismatase
SAK_RS08500	COG0436	Aminotransferase
SAK_RS08505	COG0589	response to stress
SAK_RS08510	COG0561	phosphatase activity
SAK_RS08515	COG0252	asparaginase activity
SAK_RS08525	COG4989	oxidoreductase activity
SAK_RS08530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAK_RS08535	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAK_RS08535	COG3942	CHAP domain
SAK_RS08545	COG0736	holo-[acyl-carrier-protein] synthase activity
SAK_RS08550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SAK_RS08560	COG1482	cell wall glycoprotein biosynthetic process
SAK_RS08565	COG1940	carbohydrate kinase activity
SAK_RS08570	COG2190	(PTS) system
SAK_RS08570	COG1263	PTS System
SAK_RS08570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAK_RS08575	COG1621	beta-fructofuranosidase activity
SAK_RS08580	COG1609	Transcriptional regulator
SAK_RS08585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAK_RS08595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAK_RS08615	COG2131	deaminase
SAK_RS08630	COG2814	Major facilitator Superfamily
SAK_RS08655	COG0629	single-stranded DNA binding
SAK_RS08660	COG0360	Binds together with S18 to 16S ribosomal RNA
SAK_RS08665	COG1194	a g-specific adenine glycosylase
SAK_RS08675	COG3118	belongs to the thioredoxin family
SAK_RS08705	COG0681	Belongs to the peptidase S26 family
SAK_RS08710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAK_RS08725	COG1882	Formate acetyltransferase
SAK_RS08730	COG3576	pyridoxamine 5-phosphate
SAK_RS08735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAK_RS08750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAK_RS08760	COG2814	Major facilitator Superfamily
SAK_RS08765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAK_RS08780	COG0142	geranyltranstransferase activity
SAK_RS08785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAK_RS08790	COG4988	ABC transporter
SAK_RS08795	COG1294	oxidase, subunit
SAK_RS08800	COG1271	oxidase subunit
SAK_RS08805	COG1252	NADH dehydrogenase
SAK_RS08840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAK_RS08845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SAK_RS08845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAK_RS08845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAK_RS08850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAK_RS08855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAK_RS08860	COG3711	transcriptional antiterminator
SAK_RS08860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAK_RS08880	COG4221	oxidoreductase activity
SAK_RS08890	COG0656	L-ascorbic acid biosynthetic process
SAK_RS08895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SAK_RS08910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAK_RS08915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAK_RS08920	COG0789	Transcriptional regulator
SAK_RS08935	COG2081	HI0933 family
SAK_RS08960	COG0456	acetyltransferase
SAK_RS08965	COG1214	PFAM Peptidase M22, glycoprotease
SAK_RS08980	COG3942	CHAP domain
SAK_RS08985	COG0174	glutamine synthetase
SAK_RS08990	COG0789	Transcriptional regulator
SAK_RS09005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAK_RS09030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAK_RS09055	COG1162	GTPase activity
SAK_RS09080	COG0084	hydrolase, TatD family'
SAK_RS09105	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAK_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAK_RS09115	COG1696	Membrane protein involved in D-alanine export
SAK_RS09135	COG0745	RESPONSE REGULATOR receiver
SAK_RS09145	COG3314	Sporulation integral membrane protein YlbJ
SAK_RS09155	COG3448	diguanylate cyclase activity
SAK_RS09155	COG4175	Glycine betaine
SAK_RS09160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SAK_RS09180	COG1070	Carbohydrate kinase
SAK_RS09190	COG3775	system Galactitol-specific IIC component
SAK_RS09195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAK_RS09205	COG1609	Transcriptional regulator
SAK_RS09290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAK_RS09295	COG1428	Deoxynucleoside kinase
SAK_RS09305	COG0542	response to heat
SAK_RS09310	COG4463	regulation of RNA biosynthetic process
SAK_RS09320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAK_RS09330	COG0450	alkyl hydroperoxide reductase
SAK_RS09345	COG0025	NhaP-type Na H and K H
SAK_RS09355	COG1619	proteins homologs of microcin C7 resistance protein MccF
SAK_RS09360	COG3590	peptidase
SAK_RS09385	COG1609	Transcriptional regulator
SAK_RS09410	COG2176	DNA-directed DNA polymerase activity
SAK_RS09415	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAK_RS09415	COG1388	LysM domain
SAK_RS09430	COG4589	Belongs to the CDS family
SAK_RS09435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAK_RS09440	COG1862	Preprotein translocase
SAK_RS09460	COG3493	citrate carrier protein
SAK_RS09465	COG3290	protein histidine kinase activity
SAK_RS09470	COG4565	transcriptional regulatory protein
SAK_RS09475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAK_RS09485	COG3842	ATPase activity
SAK_RS09570	COG0737	Belongs to the 5'-nucleotidase family
SAK_RS09580	COG1363	Peptidase, m42
SAK_RS09600	COG4753	response regulator
SAK_RS09600	COG2207	Transcriptional regulator
SAK_RS09605	COG2972	Histidine kinase
SAK_RS09610	COG3716	PTS system mannose fructose sorbose family IID component
SAK_RS09615	COG3715	PTS system
SAK_RS09645	COG1131	(ABC) transporter
SAK_RS09650	COG2274	protein secretion by the type I secretion system
SAK_RS09655	COG3290	protein histidine kinase activity
SAK_RS09670	COG2190	(PTS) system
SAK_RS09670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAK_RS09670	COG1263	PTS System
SAK_RS09675	COG5002	protein histidine kinase activity
SAK_RS09680	COG0745	RESPONSE REGULATOR receiver
SAK_RS09695	COG0581	inorganic phosphate transmembrane transporter activity
SAK_RS09700	COG0573	inorganic phosphate transmembrane transporter activity
SAK_RS09715	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAK_RS09730	COG0789	Transcriptional regulator
SAK_RS09740	COG0494	nUDIX hydrolase
SAK_RS09755	COG0456	acetyltransferase
SAK_RS09760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAK_RS09785	COG0582	viral genome integration into host DNA
SAK_RS09795	COG2946	Replication initiation factor
SAK_RS09815	COG2378	regulation of single-species biofilm formation
SAK_RS09820	COG0693	protein deglycase activity
SAK_RS09895	COG1131	(ABC) transporter
SAK_RS09940	COG1131	(ABC) transporter
SAK_RS09950	COG1396	sequence-specific DNA binding
SAK_RS09960	COG1694	Mazg nucleotide pyrophosphohydrolase
SAK_RS09965	COG1611	Belongs to the LOG family
SAK_RS09975	COG2897	thiosulfate sulfurtransferase activity
SAK_RS09990	COG0371	Dehydrogenase
SAK_RS10000	COG0646	methionine synthase
SAK_RS10000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAK_RS10015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SAK_RS10025	COG0745	RESPONSE REGULATOR receiver
SAK_RS10030	COG2770	Histidine kinase
SAK_RS10030	COG2205	protein histidine kinase activity
SAK_RS10045	COG2814	Major facilitator Superfamily
SAK_RS10050	COG4667	esterase of the alpha-beta hydrolase superfamily
SAK_RS10085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAK_RS10090	COG0564	pseudouridine synthase activity
SAK_RS10110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAK_RS10115	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SAK_RS10135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAK_RS10140	COG1116	anion transmembrane transporter activity
SAK_RS10140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SAK_RS10145	COG4120	Belongs to the binding-protein-dependent transport system permease family
SAK_RS10155	COG0561	phosphatase activity
SAK_RS10160	COG2514	catechol 2,3-dioxygenase activity
SAK_RS10170	COG0602	queuosine metabolic process
SAK_RS10190	COG1328	CTP reductase activity
SAK_RS10210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAK_RS10220	COG1393	Belongs to the ArsC family
SAK_RS10225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SAK_RS10235	COG2818	Glycosylase
SAK_RS10280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAK_RS10285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAK_RS10305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAK_RS10360	COG4974	Belongs to the 'phage' integrase family
SAK_RS10370	COG0745	RESPONSE REGULATOR receiver
SAK_RS10375	COG5002	protein histidine kinase activity
SAK_RS10380	COG1288	antiporter activity
SAK_RS10390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAK_RS10395	COG3852	Histidine kinase
SAK_RS10400	COG0784	Response regulator, receiver
SAK_RS10405	COG0517	IMP dehydrogenase activity
SAK_RS10405	COG1125	glycine betaine transport
SAK_RS10410	COG1174	glycine betaine transport
SAK_RS10415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAK_RS10415	COG0392	lysyltransferase activity
SAK_RS10425	COG3759	membrane
SAK_RS10550	COG0582	viral genome integration into host DNA
SAK_RS10565	COG0305	Participates in initiation and elongation during chromosome replication
SAK_RS10585	COG2095	MarC family integral membrane protein
SAK_RS10595	COG1760	l-serine dehydratase
SAK_RS10600	COG1760	l-serine dehydratase
SAK_RS10605	COG0741	lytic transglycosylase activity
SAK_RS10630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAK_RS10635	COG0612	Peptidase, M16
SAK_RS10640	COG0612	Peptidase, M16
SAK_RS10645	COG2501	S4 domain
SAK_RS10665	COG0516	GMP reductase activity
SAK_RS10665	COG0517	IMP dehydrogenase activity
SAK_RS10675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAK_RS10690	COG0454	-acetyltransferase
SAK_RS10705	COG0549	Belongs to the carbamate kinase family
SAK_RS10720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAK_RS10725	COG0488	(ABC) transporter
SAK_RS10730	COG4485	Bacterial membrane protein, YfhO
SAK_RS10750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SAK_RS10755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAK_RS10760	COG1475	DNA binding
SAK_RS10775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB