locus-tag	class	description
CDH83_RS00110	COG1396	sequence-specific DNA binding
CDH83_RS00115	COG2814	Major facilitator Superfamily
CDH83_RS00125	COG1732	Glycine betaine
CDH83_RS00265	COG0519	Catalyzes the synthesis of GMP from XMP
CDH83_RS00315	COG1695	Transcriptional regulator
CDH83_RS00330	COG1755	Isoprenylcysteine carboxyl methyltransferase
CDH83_RS00370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDH83_RS00375	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDH83_RS00395	COG1131	(ABC) transporter
CDH83_RS00405	COG1263	PTS System
CDH83_RS00405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS00405	COG2190	(PTS) system
CDH83_RS00410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDH83_RS00430	COG0768	penicillin binding
CDH83_RS00440	COG0513	Belongs to the DEAD box helicase family
CDH83_RS00455	COG1126	abc transporter atp-binding protein
CDH83_RS00465	COG0492	ferredoxin-NADP+ reductase activity
CDH83_RS00470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDH83_RS00480	COG3579	cysteine-type endopeptidase activity
CDH83_RS00485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDH83_RS00515	COG0116	Belongs to the methyltransferase superfamily
CDH83_RS00525	COG1854	S-ribosylhomocysteine lyase activity
CDH83_RS00530	COG1418	mRNA catabolic process
CDH83_RS00530	COG4372	Transposase
CDH83_RS00540	COG1131	(ABC) transporter
CDH83_RS00550	COG4585	Histidine kinase
CDH83_RS00555	COG2197	response regulator
CDH83_RS00565	COG0194	GDP metabolic process
CDH83_RS00575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDH83_RS00580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDH83_RS00585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDH83_RS00585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDH83_RS00595	COG2815	serine threonine protein kinase
CDH83_RS00595	COG0515	serine threonine protein kinase
CDH83_RS00605	COG4585	Histidine kinase
CDH83_RS00610	COG2197	response regulator
CDH83_RS00620	COG1098	S1 RNA binding domain
CDH83_RS00625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDH83_RS00630	COG1349	DNA-binding transcription factor activity
CDH83_RS00640	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDH83_RS00650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDH83_RS00655	COG1882	Formate acetyltransferase
CDH83_RS00675	COG1739	Uncharacterized protein family UPF0029
CDH83_RS00680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CDH83_RS00685	COG1040	competence protein
CDH83_RS00720	COG0527	aspartate kinase activity
CDH83_RS00725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDH83_RS00735	COG1024	Enoyl-CoA hydratase
CDH83_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDH83_RS00755	COG2070	2-Nitropropane dioxygenase
CDH83_RS00760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDH83_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
CDH83_RS00770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDH83_RS00785	COG0439	Biotin carboxylase
CDH83_RS00805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDH83_RS00820	COG3716	PTS system mannose fructose sorbose family IID component
CDH83_RS00825	COG3715	PTS system
CDH83_RS00840	COG0561	phosphatase activity
CDH83_RS00855	COG2252	PERMEase
CDH83_RS00860	COG0802	atpase or kinase
CDH83_RS00870	COG1316	TRANSCRIPTIONal
CDH83_RS00880	COG0537	adenosine 5'-monophosphoramidase activity
CDH83_RS00895	COG1131	(ABC) transporter
CDH83_RS00900	COG4473	ABC transporter
CDH83_RS00910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDH83_RS00925	COG0195	Participates in both transcription termination and antitermination
CDH83_RS00930	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDH83_RS00945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDH83_RS00970	COG2860	membrane
CDH83_RS00980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDH83_RS00980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDH83_RS00985	COG1832	CoA-binding protein
CDH83_RS01005	COG5002	protein histidine kinase activity
CDH83_RS01025	COG1268	BioY protein
CDH83_RS01030	COG1234	tRNA 3'-trailer cleavage
CDH83_RS01045	COG0166	Belongs to the GPI family
CDH83_RS01050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDH83_RS01055	COG0705	Rhomboid family
CDH83_RS01055	COG0457	Tetratricopeptide repeat
CDH83_RS01060	COG1744	ABC transporter substrate-binding protein PnrA-like
CDH83_RS01065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDH83_RS01150	COG2153	protein acetylation
CDH83_RS01160	COG1216	Glycosyl transferase, family 2
CDH83_RS01160	COG1442	glycosyl transferase family 8
CDH83_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDH83_RS01210	COG0789	Transcriptional regulator
CDH83_RS01215	COG1063	alcohol dehydrogenase
CDH83_RS01220	COG0656	L-ascorbic acid biosynthetic process
CDH83_RS01275	COG0582	viral genome integration into host DNA
CDH83_RS01305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDH83_RS01320	COG0673	inositol 2-dehydrogenase activity
CDH83_RS01330	COG3328	transposase activity
CDH83_RS01335	COG2315	Protein conserved in bacteria
CDH83_RS01350	COG0742	ribosomal rna small subunit methyltransferase
CDH83_RS01365	COG3480	Lon protease (S16) C-terminal proteolytic domain
CDH83_RS01375	COG4470	Protein conserved in bacteria
CDH83_RS01390	COG1132	(ABC) transporter
CDH83_RS01395	COG1132	(ABC) transporter
CDH83_RS01400	COG0512	Glutamine amidotransferase of anthranilate synthase
CDH83_RS01405	COG1268	BioY protein
CDH83_RS01420	COG0183	Belongs to the thiolase family
CDH83_RS01430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDH83_RS01445	COG1940	carbohydrate kinase activity
CDH83_RS01450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDH83_RS01455	COG1217	gtp-binding protein TYPA
CDH83_RS01490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDH83_RS01500	COG0762	integral membrane protein
CDH83_RS01505	COG2302	S4 RNA-binding domain
CDH83_RS01510	COG3599	regulation of cell shape
CDH83_RS01525	COG0494	nUDIX hydrolase
CDH83_RS01530	COG0542	response to heat
CDH83_RS01540	COG4703	Protein of unknown function (DUF1797)
CDH83_RS01545	COG0765	amino acid transport
CDH83_RS01550	COG1126	abc transporter atp-binding protein
CDH83_RS01555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDH83_RS01565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDH83_RS01575	COG1722	exodeoxyribonuclease VII activity
CDH83_RS01585	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDH83_RS01590	COG1438	arginine binding
CDH83_RS01595	COG0497	DNA recombination
CDH83_RS01600	COG1307	EDD domain protein, DegV family
CDH83_RS01605	COG2755	lipolytic protein G-D-S-L family
CDH83_RS01650	COG1078	dGTPase activity
CDH83_RS01675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDH83_RS01685	COG2884	Cell division ATP-binding protein ftsE
CDH83_RS01690	COG2177	Part of the ABC transporter FtsEX involved in
CDH83_RS01710	COG1199	ATP-dependent helicase activity
CDH83_RS01710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDH83_RS01715	COG0436	Aminotransferase
CDH83_RS01720	COG0017	Asparaginyl-tRNA synthetase
CDH83_RS01745	COG1660	Displays ATPase and GTPase activities
CDH83_RS01770	COG0254	rRNA binding
CDH83_RS01775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDH83_RS01780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDH83_RS01785	COG0716	FMN binding
CDH83_RS01790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDH83_RS01790	COG1605	Chorismate mutase
CDH83_RS01795	COG0038	chloride channel
CDH83_RS01805	COG0335	large ribosomal subunit rRNA binding
CDH83_RS01855	COG1136	(ABC) transporter
CDH83_RS01890	COG0772	Belongs to the SEDS family
CDH83_RS01910	COG0560	Phosphoserine phosphatase
CDH83_RS01925	COG0148	phosphopyruvate hydratase activity
CDH83_RS01960	COG3700	Belongs to the class B bacterial acid phosphatase family
CDH83_RS02000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDH83_RS02000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDH83_RS02045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDH83_RS02065	COG0270	DNA (cytosine-5-)-methyltransferase activity
CDH83_RS02105	COG4695	Portal protein
CDH83_RS02110	COG0740	serine-type endopeptidase activity
CDH83_RS02175	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDH83_RS02185	COG5433	transposase activity
CDH83_RS02190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDH83_RS02215	COG3700	Belongs to the class B bacterial acid phosphatase family
CDH83_RS02320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDH83_RS02325	COG4555	ABC transporter
CDH83_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
CDH83_RS02360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDH83_RS02365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDH83_RS02385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDH83_RS02390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDH83_RS02410	COG3064	Membrane
CDH83_RS02410	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDH83_RS02425	COG3590	peptidase
CDH83_RS02430	COG3590	peptidase
CDH83_RS02480	COG1136	(ABC) transporter
CDH83_RS02495	COG0586	Pfam SNARE associated Golgi protein
CDH83_RS02500	COG4619	ABC transporter
CDH83_RS02505	COG0390	transport system, permease component
CDH83_RS02515	COG0583	DNA-binding transcription factor activity
CDH83_RS02525	COG5433	transposase activity
CDH83_RS02540	COG2211	Major facilitator Superfamily
CDH83_RS02550	COG3250	beta-galactosidase activity
CDH83_RS02555	COG2186	Transcriptional regulator
CDH83_RS02565	COG0800	Aldolase
CDH83_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
CDH83_RS02600	COG1609	Transcriptional regulator
CDH83_RS02615	COG0438	transferase activity, transferring glycosyl groups
CDH83_RS02640	COG0765	amino acid transport
CDH83_RS02645	COG0765	amino acid transport
CDH83_RS02650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDH83_RS02655	COG1126	abc transporter atp-binding protein
CDH83_RS02660	COG0745	RESPONSE REGULATOR receiver
CDH83_RS02665	COG5002	protein histidine kinase activity
CDH83_RS02670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDH83_RS02675	COG2832	Protein of unknown function (DUF454)
CDH83_RS02685	COG1196	nuclear chromosome segregation
CDH83_RS02690	COG0561	phosphatase activity
CDH83_RS02695	COG0561	phosphatase activity
CDH83_RS02700	COG0552	protein localization to endoplasmic reticulum
CDH83_RS02705	COG3689	TIGRFAM TIGR03943 family protein
CDH83_RS02710	COG0701	Predicted permease
CDH83_RS02725	COG2183	response to ionizing radiation
CDH83_RS02730	COG3091	SprT-like family
CDH83_RS02735	COG1983	PspC domain protein
CDH83_RS02775	COG0826	peptidase U32
CDH83_RS02780	COG4443	Transcriptional Coactivator p15 (PC4)
CDH83_RS02790	COG1914	H( )-stimulated, divalent metal cation uptake system
CDH83_RS02805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDH83_RS02805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDH83_RS02830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDH83_RS02855	COG1164	Oligoendopeptidase f
CDH83_RS02865	COG5433	transposase activity
CDH83_RS02870	COG0772	Belongs to the SEDS family
CDH83_RS02890	COG0768	penicillin binding
CDH83_RS02905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDH83_RS02910	COG2223	nitrite transmembrane transporter activity
CDH83_RS02935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDH83_RS02940	COG2011	ABC-type metal ion transport system permease component
CDH83_RS02945	COG1464	Belongs to the NlpA lipoprotein family
CDH83_RS02950	COG0513	Belongs to the DEAD box helicase family
CDH83_RS02960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDH83_RS02965	COG0204	Acyl-transferase
CDH83_RS02970	COG1555	photosystem II stabilization
CDH83_RS02970	COG1596	polysaccharide export
CDH83_RS02975	COG2333	competence protein COMEC
CDH83_RS02975	COG0658	competence protein
CDH83_RS02980	COG0561	phosphatase activity
CDH83_RS02985	COG1609	Transcriptional regulator
CDH83_RS02990	COG0657	acetylesterase activity
CDH83_RS02995	COG2226	methyltransferase
CDH83_RS03005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDH83_RS03010	COG3711	transcriptional antiterminator
CDH83_RS03015	COG1263	PTS System
CDH83_RS03015	COG2190	(PTS) system
CDH83_RS03015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS03025	COG3835	regulator
CDH83_RS03030	COG1929	Belongs to the glycerate kinase type-1 family
CDH83_RS03035	COG2610	gluconate transmembrane transporter activity
CDH83_RS03045	COG1846	Transcriptional regulator
CDH83_RS03060	COG0363	glucosamine-6-phosphate deaminase activity
CDH83_RS03065	COG0435	Glutathione S-transferase
CDH83_RS03070	COG1187	pseudouridine synthase activity
CDH83_RS03095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDH83_RS03100	COG4122	O-methyltransferase activity
CDH83_RS03110	COG4894	glucomannan catabolic process
CDH83_RS03120	COG1811	Na channel or pump
CDH83_RS03125	COG1442	glycosyl transferase family 8
CDH83_RS03140	COG1476	TRANSCRIPTIONal
CDH83_RS03155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDH83_RS03160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDH83_RS03165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDH83_RS03180	COG1012	belongs to the aldehyde dehydrogenase family
CDH83_RS03185	COG0726	polysaccharide deacetylase
CDH83_RS03200	COG1956	GAF domain-containing protein
CDH83_RS03205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDH83_RS03215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDH83_RS03215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDH83_RS03245	COG4721	ABC-type cobalt transport system, permease component
CDH83_RS03250	COG1122	ATPase activity
CDH83_RS03260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDH83_RS03290	COG4109	DRTGG domain
CDH83_RS03295	COG0024	Methionine aminopeptidase
CDH83_RS03305	COG2246	polysaccharide biosynthetic process
CDH83_RS03310	COG4708	membrane
CDH83_RS03320	COG1597	lipid kinase activity
CDH83_RS03325	COG1523	belongs to the glycosyl hydrolase 13 family
CDH83_RS03340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDH83_RS03425	COG2321	neutral zinc metallopeptidase
CDH83_RS03450	COG0488	(ABC) transporter
CDH83_RS03455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDH83_RS03460	COG0022	dehydrogenase e1 component
CDH83_RS03460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDH83_RS03465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDH83_RS03475	COG0095	Lipoate-protein ligase
CDH83_RS03480	COG3442	glutamine amidotransferase
CDH83_RS03485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDH83_RS03490	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDH83_RS03515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDH83_RS03525	COG0647	UMP catabolic process
CDH83_RS03535	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CDH83_RS03540	COG1518	maintenance of DNA repeat elements
CDH83_RS03545	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDH83_RS03565	COG0481	GTPase activity
CDH83_RS03575	COG1418	mRNA catabolic process
CDH83_RS03580	COG0456	acetyltransferase
CDH83_RS03590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDH83_RS03675	COG0741	lytic transglycosylase activity
CDH83_RS03675	COG0791	NLP P60 protein
CDH83_RS03705	COG2946	Replication initiation factor
CDH83_RS03715	COG1674	ftsk spoiiie
CDH83_RS03740	COG1131	(ABC) transporter
CDH83_RS03745	COG1725	Transcriptional regulator
CDH83_RS03755	COG0205	6-phosphofructokinase activity
CDH83_RS03760	COG0469	pyruvate kinase activity
CDH83_RS03780	COG5433	transposase activity
CDH83_RS03785	COG2824	Alkylphosphonate utilization operon protein PhnA
CDH83_RS03790	COG0765	amino acid transport
CDH83_RS03795	COG1126	abc transporter atp-binding protein
CDH83_RS03810	COG1072	(Pantothenic acid kinase))
CDH83_RS03815	COG2813	Specifically methylates the guanine in position
CDH83_RS03825	COG1744	ABC transporter substrate-binding protein PnrA-like
CDH83_RS03830	COG3845	ABC transporter
CDH83_RS03835	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDH83_RS03840	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDH83_RS03860	COG3764	Sortase (surface protein transpeptidase)
CDH83_RS03865	COG0346	lactoylglutathione lyase activity
CDH83_RS03890	COG2188	Transcriptional regulator
CDH83_RS03905	COG1464	Belongs to the NlpA lipoprotein family
CDH83_RS03920	COG1136	(ABC) transporter
CDH83_RS03930	COG0745	RESPONSE REGULATOR receiver
CDH83_RS03935	COG5002	protein histidine kinase activity
CDH83_RS03940	COG4974	Belongs to the 'phage' integrase family
CDH83_RS03960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDH83_RS03965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CDH83_RS03970	COG5002	protein histidine kinase activity
CDH83_RS03975	COG0745	RESPONSE REGULATOR receiver
CDH83_RS03985	COG0704	Plays a role in the regulation of phosphate uptake
CDH83_RS03990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDH83_RS03995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDH83_RS04000	COG0581	inorganic phosphate transmembrane transporter activity
CDH83_RS04005	COG0573	inorganic phosphate transmembrane transporter activity
CDH83_RS04015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDH83_RS04015	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDH83_RS04020	COG0483	inositol monophosphate 1-phosphatase activity
CDH83_RS04035	COG0196	riboflavin kinase activity
CDH83_RS04040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDH83_RS04070	COG1136	(ABC) transporter
CDH83_RS04075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDH83_RS04080	COG0758	DNA mediated transformation
CDH83_RS04085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CDH83_RS04090	COG4604	ABC transporter, ATP-binding protein
CDH83_RS04095	COG4605	iron ion homeostasis
CDH83_RS04100	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDH83_RS04105	COG0110	maltose O-acetyltransferase activity
CDH83_RS04115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDH83_RS04120	COG1376	ErfK ybiS ycfS ynhG family protein
CDH83_RS04125	COG1966	Carbon starvation protein
CDH83_RS04130	COG3279	Response regulator of the LytR AlgR family
CDH83_RS04135	COG3275	phosphorelay sensor kinase activity
CDH83_RS04275	COG0505	Belongs to the CarA family
CDH83_RS04285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDH83_RS04290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDH83_RS04305	COG0488	(ABC) transporter
CDH83_RS04315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDH83_RS04330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDH83_RS04370	COG0095	Lipoate-protein ligase
CDH83_RS04380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDH83_RS04385	COG4684	Psort location CytoplasmicMembrane, score
CDH83_RS04390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDH83_RS04410	COG1132	(ABC) transporter
CDH83_RS04440	COG2890	protein-(glutamine-N5) methyltransferase activity
CDH83_RS04455	COG1942	4-Oxalocrotonate Tautomerase
CDH83_RS04475	COG1053	succinate dehydrogenase
CDH83_RS04475	COG3976	FMN-binding domain protein
CDH83_RS04475	COG0431	NADPH-dependent FMN reductase
CDH83_RS04485	COG2233	PERMEase
CDH83_RS04500	COG0477	Major facilitator Superfamily
CDH83_RS04515	COG4221	oxidoreductase activity
CDH83_RS04520	COG0280	phosphate acetyltransferase
CDH83_RS04525	COG0564	pseudouridine synthase activity
CDH83_RS04535	COG2357	RelA SpoT domain protein
CDH83_RS04550	COG1104	cysteine desulfurase activity
CDH83_RS04570	COG0628	permease
CDH83_RS04585	COG0561	phosphatase activity
CDH83_RS04600	COG0038	chloride channel
CDH83_RS04610	COG1177	transmembrane transport
CDH83_RS04615	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDH83_RS04625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDH83_RS04630	COG5433	transposase activity
CDH83_RS04635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDH83_RS04655	COG0285	dihydrofolate synthase activity
CDH83_RS04660	COG2962	Rard protein
CDH83_RS04675	COG0726	polysaccharide deacetylase
CDH83_RS04680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDH83_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
CDH83_RS04790	COG1115	amino acid carrier protein
CDH83_RS04795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDH83_RS04805	COG1346	cytolysis
CDH83_RS04820	COG0539	negative regulation of cytoplasmic translation
CDH83_RS04840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDH83_RS04850	COG0187	DNA topoisomerase II activity
CDH83_RS04855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDH83_RS04860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDH83_RS04870	COG2755	lipolytic protein G-D-S-L family
CDH83_RS04870	COG1083	cytidylyl-transferase
CDH83_RS04885	COG2089	acid synthase
CDH83_RS04900	COG1442	glycosyl transferase family 8
CDH83_RS04900	COG1216	Glycosyl transferase, family 2
CDH83_RS04905	COG1216	Glycosyl transferase, family 2
CDH83_RS04905	COG1442	glycosyl transferase family 8
CDH83_RS04920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDH83_RS04925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDH83_RS04945	COG1316	TRANSCRIPTIONal
CDH83_RS04970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDH83_RS05005	COG5433	transposase activity
CDH83_RS05010	COG3842	ATPase activity
CDH83_RS05025	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CDH83_RS05030	COG3527	Alpha-acetolactate decarboxylase
CDH83_RS05035	COG0028	Belongs to the TPP enzyme family
CDH83_RS05040	COG0457	Tetratricopeptide repeat
CDH83_RS05045	COG0628	permease
CDH83_RS05055	COG1051	belongs to the nudix hydrolase family
CDH83_RS05065	COG5433	transposase activity
CDH83_RS05075	COG1088	dTDP-glucose 4,6-dehydratase activity
CDH83_RS05080	COG0135	phosphoribosylanthranilate isomerase activity
CDH83_RS05090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDH83_RS05095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDH83_RS05105	COG2384	SAM-dependent methyltransferase
CDH83_RS05125	COG5433	transposase activity
CDH83_RS05140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDH83_RS05140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDH83_RS05145	COG0300	oxidoreductase activity
CDH83_RS05160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDH83_RS05180	COG1523	belongs to the glycosyl hydrolase 13 family
CDH83_RS05190	COG1573	uracil-dna glycosylase
CDH83_RS05195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDH83_RS05220	COG0534	Mate efflux family protein
CDH83_RS05265	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDH83_RS05270	COG5433	transposase activity
CDH83_RS05290	COG2176	DNA-directed DNA polymerase activity
CDH83_RS05300	COG4974	Belongs to the 'phage' integrase family
CDH83_RS05310	COG1396	sequence-specific DNA binding
CDH83_RS05315	COG3843	relaxase mobilization nuclease domain protein
CDH83_RS05360	COG2217	Heavy metal translocating P-type atpase
CDH83_RS05365	COG2217	Heavy metal translocating P-type atpase
CDH83_RS05405	COG1388	LysM domain
CDH83_RS05405	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDH83_RS05425	COG0640	Transcriptional regulator
CDH83_RS05430	COG2217	Heavy metal translocating P-type atpase
CDH83_RS05450	COG0842	Transport permease protein
CDH83_RS05455	COG1131	(ABC) transporter
CDH83_RS05465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDH83_RS05585	COG1129	ABC transporter
CDH83_RS05590	COG1132	(ABC) transporter
CDH83_RS05595	COG1132	(ABC) transporter
CDH83_RS05645	COG1401	restriction endodeoxyribonuclease activity
CDH83_RS05650	COG0270	DNA (cytosine-5-)-methyltransferase activity
CDH83_RS05680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDH83_RS05680	COG0551	DNA topoisomerase type I activity
CDH83_RS05740	COG4804	nuclease activity
CDH83_RS05780	COG0534	Mate efflux family protein
CDH83_RS05930	COG0270	DNA (cytosine-5-)-methyltransferase activity
CDH83_RS05970	COG2040	homocysteine
CDH83_RS06015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDH83_RS06025	COG3425	synthase
CDH83_RS06040	COG1272	protein, Hemolysin III
CDH83_RS06080	COG5433	transposase activity
CDH83_RS06090	COG0745	RESPONSE REGULATOR receiver
CDH83_RS06095	COG2357	RelA SpoT domain protein
CDH83_RS06100	COG1132	(ABC) transporter
CDH83_RS06115	COG0737	Belongs to the 5'-nucleotidase family
CDH83_RS06120	COG0242	peptide deformylase activity
CDH83_RS06125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDH83_RS06135	COG1132	(ABC) transporter
CDH83_RS06150	COG0488	(ABC) transporter
CDH83_RS06180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDH83_RS06180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDH83_RS06180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDH83_RS06185	COG1105	Belongs to the carbohydrate kinase PfkB family
CDH83_RS06190	COG1349	DNA-binding transcription factor activity
CDH83_RS06195	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDH83_RS06195	COG1388	LysM domain
CDH83_RS06245	COG1837	Belongs to the UPF0109 family
CDH83_RS06250	COG0228	four-way junction DNA binding
CDH83_RS06255	COG0577	efflux transmembrane transporter activity
CDH83_RS06260	COG1136	(ABC) transporter
CDH83_RS06265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDH83_RS06275	COG0505	Belongs to the CarA family
CDH83_RS06285	COG0564	pseudouridine synthase activity
CDH83_RS06295	COG0583	DNA-binding transcription factor activity
CDH83_RS06300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDH83_RS06325	COG1104	cysteine desulfurase activity
CDH83_RS06335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDH83_RS06360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDH83_RS06365	COG1368	sulfuric ester hydrolase activity
CDH83_RS06370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDH83_RS06380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDH83_RS06410	COG2244	polysaccharide biosynthetic process
CDH83_RS06420	COG1120	ATPase activity
CDH83_RS06425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDH83_RS06430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDH83_RS06435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDH83_RS06450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDH83_RS06455	COG1253	flavin adenine dinucleotide binding
CDH83_RS06460	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDH83_RS06465	COG1242	4 iron, 4 sulfur cluster binding
CDH83_RS06470	COG0671	phosphoesterase, PA-phosphatase related
CDH83_RS06475	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CDH83_RS06515	COG0297	glycogen (starch) synthase activity
CDH83_RS06555	COG3475	LICD family
CDH83_RS06570	COG0463	Glycosyl transferase, family 2
CDH83_RS06575	COG1215	transferase activity, transferring glycosyl groups
CDH83_RS06585	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDH83_RS06590	COG2151	metal-sulfur cluster biosynthetic enzyme
CDH83_RS06595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDH83_RS06600	COG0358	DNA primase activity
CDH83_RS06605	COG1970	mechanosensitive ion channel activity
CDH83_RS06620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDH83_RS06625	COG0004	ammonium transporteR
CDH83_RS06635	COG1054	Belongs to the UPF0176 family
CDH83_RS06645	COG2271	Major facilitator Superfamily
CDH83_RS06655	COG0058	SHG alpha-glucan phosphorylase activity
CDH83_RS06660	COG1640	4-alpha-glucanotransferase
CDH83_RS06665	COG1609	Transcriptional regulator
CDH83_RS06675	COG1175	transmembrane transport
CDH83_RS06680	COG3833	ABC-type maltose transport systems, permease component
CDH83_RS06685	COG3104	oligopeptide transport
CDH83_RS06705	COG0438	transferase activity, transferring glycosyl groups
CDH83_RS06740	COG0201	protein transport
CDH83_RS06745	COG1442	glycosyl transferase family 8
CDH83_RS06750	COG1216	Glycosyl transferase, family 2
CDH83_RS06750	COG1442	glycosyl transferase family 8
CDH83_RS06760	COG1216	Glycosyl transferase, family 2
CDH83_RS06760	COG1442	glycosyl transferase family 8
CDH83_RS06765	COG1442	glycosyl transferase family 8
CDH83_RS06795	COG0765	amino acid transport
CDH83_RS06800	COG1126	abc transporter atp-binding protein
CDH83_RS06825	COG2309	aminopeptidase activity
CDH83_RS06835	COG0154	amidase activity
CDH83_RS06840	COG1187	pseudouridine synthase activity
CDH83_RS06845	COG0656	L-ascorbic acid biosynthetic process
CDH83_RS06850	COG0778	Nitroreductase
CDH83_RS06855	COG0346	lactoylglutathione lyase activity
CDH83_RS06860	COG0463	Glycosyl transferase, family 2
CDH83_RS06865	COG1113	amino acid transport
CDH83_RS06870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDH83_RS06875	COG0557	exoribonuclease II activity
CDH83_RS06890	COG2814	Major facilitator Superfamily
CDH83_RS06900	COG1131	(ABC) transporter
CDH83_RS06910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDH83_RS06915	COG1396	sequence-specific DNA binding
CDH83_RS06970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDH83_RS06975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDH83_RS07005	COG1702	phosphate starvation-inducible protein PhoH
CDH83_RS07030	COG0233	cytoplasmic translational termination
CDH83_RS07045	COG0444	Belongs to the ABC transporter superfamily
CDH83_RS07050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDH83_RS07055	COG0601	transmembrane transport
CDH83_RS07060	COG0747	negative chemotaxis
CDH83_RS07065	COG0081	regulation of translation
CDH83_RS07085	COG1473	amidohydrolase
CDH83_RS07090	COG0583	DNA-binding transcription factor activity
CDH83_RS07110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDH83_RS07120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDH83_RS07145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDH83_RS07180	COG0673	inositol 2-dehydrogenase activity
CDH83_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
CDH83_RS07250	COG1114	Component of the transport system for branched-chain amino acids
CDH83_RS07255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDH83_RS07255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDH83_RS07275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDH83_RS07285	COG0708	Exodeoxyribonuclease III
CDH83_RS07290	COG1393	Belongs to the ArsC family
CDH83_RS07295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDH83_RS07300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDH83_RS07340	COG0470	DNA polymerase III
CDH83_RS07355	COG0517	IMP dehydrogenase activity
CDH83_RS07375	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDH83_RS07395	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDH83_RS07400	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDH83_RS07410	COG0531	amino acid
CDH83_RS07415	COG0569	domain protein
CDH83_RS07420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDH83_RS07430	COG1187	pseudouridine synthase activity
CDH83_RS07480	COG1827	regulation of RNA biosynthetic process
CDH83_RS07495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDH83_RS07500	COG1254	Belongs to the acylphosphatase family
CDH83_RS07510	COG0765	amino acid transport
CDH83_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDH83_RS07530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDH83_RS07565	COG1484	DNA-dependent DNA replication
CDH83_RS07580	COG5002	protein histidine kinase activity
CDH83_RS07585	COG0745	RESPONSE REGULATOR receiver
CDH83_RS07600	COG1704	LemA family
CDH83_RS07610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDH83_RS07615	COG0569	domain protein
CDH83_RS07640	COG1114	Component of the transport system for branched-chain amino acids
CDH83_RS07645	COG1063	alcohol dehydrogenase
CDH83_RS07670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDH83_RS07675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDH83_RS07685	COG0217	transcriptional regulatory protein
CDH83_RS07695	COG2376	Dihydroxyacetone kinase
CDH83_RS07700	COG1309	transcriptional regulator
CDH83_RS07710	COG2376	Dihydroxyacetone kinase
CDH83_RS07715	COG1461	Dihydroxyacetone kinase
CDH83_RS07720	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CDH83_RS07725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDH83_RS07735	COG0789	Transcriptional regulator
CDH83_RS07750	COG2226	methyltransferase
CDH83_RS07755	COG0799	negative regulation of ribosome biogenesis
CDH83_RS07765	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDH83_RS07770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDH83_RS07775	COG1534	Rna-binding protein
CDH83_RS07780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDH83_RS07785	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CDH83_RS07790	COG5433	transposase activity
CDH83_RS07815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDH83_RS07815	COG0574	Belongs to the PEP-utilizing enzyme family
CDH83_RS07825	COG0517	IMP dehydrogenase activity
CDH83_RS07835	COG1335	isochorismatase
CDH83_RS07840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDH83_RS07845	COG0436	Aminotransferase
CDH83_RS07850	COG0589	response to stress
CDH83_RS07855	COG0561	phosphatase activity
CDH83_RS07860	COG0252	asparaginase activity
CDH83_RS07870	COG4989	oxidoreductase activity
CDH83_RS07875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDH83_RS07880	COG3942	CHAP domain
CDH83_RS07880	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDH83_RS07890	COG0736	holo-[acyl-carrier-protein] synthase activity
CDH83_RS07895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDH83_RS07905	COG5433	transposase activity
CDH83_RS07910	COG1482	cell wall glycoprotein biosynthetic process
CDH83_RS07915	COG1940	carbohydrate kinase activity
CDH83_RS07920	COG1263	PTS System
CDH83_RS07920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS07920	COG2190	(PTS) system
CDH83_RS07925	COG1621	beta-fructofuranosidase activity
CDH83_RS07930	COG1609	Transcriptional regulator
CDH83_RS07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDH83_RS07945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDH83_RS08005	COG2131	deaminase
CDH83_RS08020	COG2814	Major facilitator Superfamily
CDH83_RS08050	COG0629	single-stranded DNA binding
CDH83_RS08055	COG0360	Binds together with S18 to 16S ribosomal RNA
CDH83_RS08060	COG1194	a g-specific adenine glycosylase
CDH83_RS08070	COG3118	belongs to the thioredoxin family
CDH83_RS08100	COG0681	Belongs to the peptidase S26 family
CDH83_RS08105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDH83_RS08120	COG1882	Formate acetyltransferase
CDH83_RS08125	COG3576	pyridoxamine 5-phosphate
CDH83_RS08130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDH83_RS08145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDH83_RS08155	COG2814	Major facilitator Superfamily
CDH83_RS08160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDH83_RS08175	COG0142	geranyltranstransferase activity
CDH83_RS08180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CDH83_RS08185	COG4988	ABC transporter
CDH83_RS08190	COG1294	oxidase, subunit
CDH83_RS08195	COG1271	oxidase subunit
CDH83_RS08200	COG1252	NADH dehydrogenase
CDH83_RS08225	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDH83_RS08230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDH83_RS08235	COG0789	Transcriptional regulator
CDH83_RS08255	COG5433	transposase activity
CDH83_RS08260	COG2081	HI0933 family
CDH83_RS08290	COG0456	acetyltransferase
CDH83_RS08295	COG1214	PFAM Peptidase M22, glycoprotease
CDH83_RS08310	COG3942	CHAP domain
CDH83_RS08315	COG0174	glutamine synthetase
CDH83_RS08320	COG0789	Transcriptional regulator
CDH83_RS08335	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CDH83_RS08365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDH83_RS08415	COG0084	hydrolase, TatD family'
CDH83_RS08440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CDH83_RS08445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDH83_RS08450	COG1696	Membrane protein involved in D-alanine export
CDH83_RS08470	COG0745	RESPONSE REGULATOR receiver
CDH83_RS08480	COG3314	Sporulation integral membrane protein YlbJ
CDH83_RS08495	COG3448	diguanylate cyclase activity
CDH83_RS08495	COG4175	Glycine betaine
CDH83_RS08505	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDH83_RS08525	COG1070	Carbohydrate kinase
CDH83_RS08535	COG3775	system Galactitol-specific IIC component
CDH83_RS08540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDH83_RS08550	COG1609	Transcriptional regulator
CDH83_RS08600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDH83_RS08630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDH83_RS08635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDH83_RS08640	COG1428	Deoxynucleoside kinase
CDH83_RS08650	COG0542	response to heat
CDH83_RS08655	COG4463	regulation of RNA biosynthetic process
CDH83_RS08665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDH83_RS08675	COG0450	alkyl hydroperoxide reductase
CDH83_RS08690	COG0025	NhaP-type Na H and K H
CDH83_RS08700	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDH83_RS08705	COG3590	peptidase
CDH83_RS08735	COG1609	Transcriptional regulator
CDH83_RS08745	COG3716	PTS system mannose fructose sorbose family IID component
CDH83_RS08750	COG3715	PTS system
CDH83_RS08755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS08760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDH83_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
CDH83_RS08815	COG2176	DNA-directed DNA polymerase activity
CDH83_RS08820	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDH83_RS08820	COG1388	LysM domain
CDH83_RS08835	COG4589	Belongs to the CDS family
CDH83_RS08840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDH83_RS08845	COG1862	Preprotein translocase
CDH83_RS08865	COG3493	citrate carrier protein
CDH83_RS08870	COG3290	protein histidine kinase activity
CDH83_RS08875	COG4565	transcriptional regulatory protein
CDH83_RS08880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDH83_RS08890	COG3842	ATPase activity
CDH83_RS08960	COG1490	D-aminoacyl-tRNA deacylase activity
CDH83_RS08970	COG0737	Belongs to the 5'-nucleotidase family
CDH83_RS08980	COG1363	Peptidase, m42
CDH83_RS08995	COG2207	Transcriptional regulator
CDH83_RS08995	COG4753	response regulator
CDH83_RS09000	COG2972	Histidine kinase
CDH83_RS09005	COG3716	PTS system mannose fructose sorbose family IID component
CDH83_RS09010	COG3715	PTS system
CDH83_RS09040	COG1131	(ABC) transporter
CDH83_RS09050	COG3279	Response regulator of the LytR AlgR family
CDH83_RS09060	COG2190	(PTS) system
CDH83_RS09060	COG1263	PTS System
CDH83_RS09060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS09065	COG5002	protein histidine kinase activity
CDH83_RS09070	COG0745	RESPONSE REGULATOR receiver
CDH83_RS09080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDH83_RS09085	COG0581	inorganic phosphate transmembrane transporter activity
CDH83_RS09090	COG0573	inorganic phosphate transmembrane transporter activity
CDH83_RS09105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDH83_RS09120	COG0789	Transcriptional regulator
CDH83_RS09145	COG0456	acetyltransferase
CDH83_RS09150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDH83_RS09165	COG0582	viral genome integration into host DNA
CDH83_RS09205	COG0433	COG0433 Predicted ATPase
CDH83_RS09235	COG4115	mRNA cleavage
CDH83_RS09270	COG3620	sequence-specific DNA binding
CDH83_RS09285	COG1674	ftsk spoiiie
CDH83_RS09320	COG1914	H( )-stimulated, divalent metal cation uptake system
CDH83_RS09330	COG1131	(ABC) transporter
CDH83_RS09370	COG1131	(ABC) transporter
CDH83_RS09380	COG1396	sequence-specific DNA binding
CDH83_RS09390	COG1694	Mazg nucleotide pyrophosphohydrolase
CDH83_RS09425	COG0371	Dehydrogenase
CDH83_RS09435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDH83_RS09435	COG0646	methionine synthase
CDH83_RS09440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDH83_RS09450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDH83_RS09465	COG0745	RESPONSE REGULATOR receiver
CDH83_RS09470	COG2205	protein histidine kinase activity
CDH83_RS09470	COG2770	Histidine kinase
CDH83_RS09480	COG0495	leucyl-tRNA aminoacylation
CDH83_RS09485	COG2814	Major facilitator Superfamily
CDH83_RS09490	COG4667	esterase of the alpha-beta hydrolase superfamily
CDH83_RS09495	COG1442	glycosyl transferase family 8
CDH83_RS09500	COG1442	glycosyl transferase family 8
CDH83_RS09525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDH83_RS09530	COG0564	pseudouridine synthase activity
CDH83_RS09550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDH83_RS09555	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CDH83_RS09575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDH83_RS09580	COG1116	anion transmembrane transporter activity
CDH83_RS09580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDH83_RS09590	COG0561	phosphatase activity
CDH83_RS09595	COG2514	catechol 2,3-dioxygenase activity
CDH83_RS09605	COG0602	queuosine metabolic process
CDH83_RS09625	COG1328	CTP reductase activity
CDH83_RS09645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDH83_RS09655	COG1393	Belongs to the ArsC family
CDH83_RS09660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDH83_RS09670	COG2818	Glycosylase
CDH83_RS09685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDH83_RS09720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDH83_RS09725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDH83_RS09735	COG0124	histidyl-tRNA synthetase
CDH83_RS09745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDH83_RS09755	COG0745	RESPONSE REGULATOR receiver
CDH83_RS09760	COG5002	protein histidine kinase activity
CDH83_RS09765	COG1288	antiporter activity
CDH83_RS09775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDH83_RS09780	COG3852	Histidine kinase
CDH83_RS09785	COG0784	Response regulator, receiver
CDH83_RS09790	COG0517	IMP dehydrogenase activity
CDH83_RS09790	COG1125	glycine betaine transport
CDH83_RS09795	COG1174	glycine betaine transport
CDH83_RS09800	COG0392	lysyltransferase activity
CDH83_RS09800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDH83_RS09810	COG3759	membrane
CDH83_RS09840	COG0305	Participates in initiation and elongation during chromosome replication
CDH83_RS09855	COG0445	tRNA wobble uridine modification
CDH83_RS09860	COG2095	MarC family integral membrane protein
CDH83_RS09865	COG0482	sulfurtransferase activity
CDH83_RS09870	COG1760	l-serine dehydratase
CDH83_RS09875	COG1760	l-serine dehydratase
CDH83_RS09880	COG0741	lytic transglycosylase activity
CDH83_RS09905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDH83_RS09910	COG0612	Peptidase, M16
CDH83_RS09915	COG0612	Peptidase, M16
CDH83_RS09920	COG2501	S4 domain
CDH83_RS09940	COG0517	IMP dehydrogenase activity
CDH83_RS09940	COG0516	GMP reductase activity
CDH83_RS09950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDH83_RS09965	COG0454	-acetyltransferase
CDH83_RS09970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDH83_RS09995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDH83_RS10000	COG0488	(ABC) transporter
CDH83_RS10005	COG4485	Bacterial membrane protein, YfhO
CDH83_RS10025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDH83_RS10030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDH83_RS10035	COG1475	DNA binding
CDH83_RS10045	COG0592	DNA-directed DNA polymerase activity
CDH83_RS10050	COG1597	lipid kinase activity
CDH83_RS10065	COG0012	GTP binding
CDH83_RS10075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDH83_RS10085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDH83_RS10115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDH83_RS10300	COG0436	Aminotransferase
CDH83_RS10315	COG0416	fatty acid biosynthetic process
CDH83_RS10320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDH83_RS10330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDH83_RS10345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDH83_RS10355	COG0138	bifunctional purine biosynthesis protein purh
CDH83_RS10370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CDH83_RS10380	COG1175	transmembrane transport
CDH83_RS10385	COG0395	ABC-type sugar transport system, permease component
CDH83_RS10400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDH83_RS10410	COG3458	cephalosporin-C deacetylase activity
CDH83_RS10425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDH83_RS10440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDH83_RS10455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDH83_RS10465	COG2755	lipolytic protein G-D-S-L family
CDH83_RS10465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDH83_RS10470	COG1012	belongs to the aldehyde dehydrogenase family
CDH83_RS10470	COG1454	alcohol dehydrogenase
CDH83_RS10475	COG1064	alcohol dehydrogenase
CDH83_RS10485	COG0534	Mate efflux family protein
CDH83_RS10595	COG0201	protein transport
CDH83_RS10600	COG0563	adenylate kinase activity
CDH83_RS10615	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDH83_RS10625	COG0202	RNA polymerase activity
CDH83_RS10770	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDH83_RS10785	COG0443	Heat shock 70 kDa protein
CDH83_RS10795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDH83_RS10805	COG0351	phosphomethylpyrimidine kinase
CDH83_RS10810	COG4720	Psort location CytoplasmicMembrane, score
CDH83_RS10820	COG0668	transmembrane transport
CDH83_RS10850	COG0756	dUTP diphosphatase activity
CDH83_RS10865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDH83_RS10875	COG1879	ABC-type sugar transport system periplasmic component
CDH83_RS10880	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDH83_RS10895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDH83_RS10900	COG1609	Transcriptional regulator
CDH83_RS10910	COG0577	efflux transmembrane transporter activity
CDH83_RS10915	COG1136	(ABC) transporter
CDH83_RS10920	COG0745	RESPONSE REGULATOR receiver
CDH83_RS10925	COG5002	protein histidine kinase activity
CDH83_RS10940	COG0191	fructose-bisphosphate aldolase activity
CDH83_RS10960	COG1461	Dihydroxyacetone kinase
CDH83_RS10980	COG1126	abc transporter atp-binding protein
CDH83_RS10985	COG0765	amino acid transport
CDH83_RS11005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDH83_RS11015	COG0719	Fe-S assembly protein
CDH83_RS11020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDH83_RS11030	COG0719	Fe-S assembly protein
CDH83_RS11035	COG1686	Belongs to the peptidase S11 family
CDH83_RS11040	COG1686	Belongs to the peptidase S11 family
CDH83_RS11045	COG4166	transmembrane transport
CDH83_RS11050	COG0601	transmembrane transport
CDH83_RS11055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDH83_RS11060	COG0444	Belongs to the ABC transporter superfamily
CDH83_RS11065	COG4608	Belongs to the ABC transporter superfamily
CDH83_RS11105	COG1121	(ABC) transporter
CDH83_RS11110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDH83_RS11125	COG4499	WXG100 protein secretion system (Wss), protein YukC
CDH83_RS11125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDH83_RS11150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDH83_RS11155	COG1459	type II secretion system
CDH83_RS11200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDH83_RS11205	COG1363	Peptidase, m42
CDH83_RS11220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDH83_RS11225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDH83_RS11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDH83_RS11260	COG1346	cytolysis
CDH83_RS11275	COG0601	transmembrane transport
CDH83_RS11280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDH83_RS11285	COG1122	ATPase activity
CDH83_RS11295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDH83_RS11295	COG1263	PTS System
CDH83_RS11300	COG0366	Alpha amylase catalytic
CDH83_RS11305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDH83_RS11320	COG3959	Transketolase, thiamine diphosphate binding domain
CDH83_RS11325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDH83_RS11330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDH83_RS11350	COG1045	serine acetyltransferase
CDH83_RS11365	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CDH83_RS11395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly