locus-tag	class	description
H1A19_RS00010	COG0592	DNA-directed DNA polymerase activity
H1A19_RS00015	COG1597	lipid kinase activity
H1A19_RS00030	COG0012	GTP binding
H1A19_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1A19_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1A19_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1A19_RS00260	COG0436	Aminotransferase
H1A19_RS00275	COG0416	fatty acid biosynthetic process
H1A19_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1A19_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1A19_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1A19_RS00315	COG0138	bifunctional purine biosynthesis protein purh
H1A19_RS00330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H1A19_RS00340	COG1175	transmembrane transport
H1A19_RS00345	COG0395	ABC-type sugar transport system, permease component
H1A19_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1A19_RS00370	COG3458	cephalosporin-C deacetylase activity
H1A19_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1A19_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1A19_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1A19_RS00425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H1A19_RS00425	COG2755	lipolytic protein G-D-S-L family
H1A19_RS00430	COG1454	alcohol dehydrogenase
H1A19_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
H1A19_RS00435	COG1064	alcohol dehydrogenase
H1A19_RS00445	COG0534	Mate efflux family protein
H1A19_RS00555	COG0201	protein transport
H1A19_RS00560	COG0563	adenylate kinase activity
H1A19_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H1A19_RS00585	COG0202	RNA polymerase activity
H1A19_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1A19_RS00745	COG0443	Heat shock 70 kDa protein
H1A19_RS00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1A19_RS00765	COG0351	phosphomethylpyrimidine kinase
H1A19_RS00770	COG4720	Psort location CytoplasmicMembrane, score
H1A19_RS00780	COG0668	transmembrane transport
H1A19_RS00810	COG0756	dUTP diphosphatase activity
H1A19_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1A19_RS00835	COG1879	ABC-type sugar transport system periplasmic component
H1A19_RS00840	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1A19_RS00855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1A19_RS00860	COG1609	Transcriptional regulator
H1A19_RS00865	COG0577	efflux transmembrane transporter activity
H1A19_RS00870	COG1136	(ABC) transporter
H1A19_RS00875	COG0745	RESPONSE REGULATOR receiver
H1A19_RS00880	COG5002	protein histidine kinase activity
H1A19_RS00895	COG0191	fructose-bisphosphate aldolase activity
H1A19_RS00915	COG1461	Dihydroxyacetone kinase
H1A19_RS00935	COG1126	abc transporter atp-binding protein
H1A19_RS00940	COG0765	amino acid transport
H1A19_RS00960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1A19_RS00970	COG0719	Fe-S assembly protein
H1A19_RS00975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1A19_RS00985	COG0719	Fe-S assembly protein
H1A19_RS00990	COG1686	Belongs to the peptidase S11 family
H1A19_RS00995	COG1686	Belongs to the peptidase S11 family
H1A19_RS01000	COG4166	transmembrane transport
H1A19_RS01005	COG0601	transmembrane transport
H1A19_RS01010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1A19_RS01015	COG0444	Belongs to the ABC transporter superfamily
H1A19_RS01020	COG4608	Belongs to the ABC transporter superfamily
H1A19_RS01060	COG1121	(ABC) transporter
H1A19_RS01065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1A19_RS01080	COG4499	WXG100 protein secretion system (Wss), protein YukC
H1A19_RS01080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1A19_RS01105	COG1459	type II secretion system
H1A19_RS01150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1A19_RS01155	COG1363	Peptidase, m42
H1A19_RS01170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1A19_RS01175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1A19_RS01190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1A19_RS01210	COG1346	cytolysis
H1A19_RS01220	COG0601	transmembrane transport
H1A19_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1A19_RS01230	COG1122	ATPase activity
H1A19_RS01240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS01240	COG1263	PTS System
H1A19_RS01245	COG0366	Alpha amylase catalytic
H1A19_RS01250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1A19_RS01265	COG3959	Transketolase, thiamine diphosphate binding domain
H1A19_RS01270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1A19_RS01275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1A19_RS01295	COG1045	serine acetyltransferase
H1A19_RS01310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H1A19_RS01330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H1A19_RS01340	COG4974	Belongs to the 'phage' integrase family
H1A19_RS01430	COG1396	sequence-specific DNA binding
H1A19_RS01435	COG2814	Major facilitator Superfamily
H1A19_RS01445	COG1732	Glycine betaine
H1A19_RS01540	COG0582	viral genome integration into host DNA
H1A19_RS01610	COG0519	Catalyzes the synthesis of GMP from XMP
H1A19_RS01660	COG1695	Transcriptional regulator
H1A19_RS01675	COG1755	Isoprenylcysteine carboxyl methyltransferase
H1A19_RS01715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1A19_RS01720	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1A19_RS01740	COG1131	(ABC) transporter
H1A19_RS01750	COG1263	PTS System
H1A19_RS01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS01750	COG2190	(PTS) system
H1A19_RS01755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H1A19_RS01775	COG0768	penicillin binding
H1A19_RS01785	COG0513	Belongs to the DEAD box helicase family
H1A19_RS01800	COG1126	abc transporter atp-binding protein
H1A19_RS01810	COG0492	ferredoxin-NADP+ reductase activity
H1A19_RS01815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H1A19_RS01825	COG3579	cysteine-type endopeptidase activity
H1A19_RS01830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1A19_RS01855	COG0116	Belongs to the methyltransferase superfamily
H1A19_RS01865	COG1854	S-ribosylhomocysteine lyase activity
H1A19_RS01870	COG4372	Transposase
H1A19_RS01870	COG1418	mRNA catabolic process
H1A19_RS01875	COG1131	(ABC) transporter
H1A19_RS01885	COG4585	Histidine kinase
H1A19_RS01890	COG2197	response regulator
H1A19_RS01900	COG0194	GDP metabolic process
H1A19_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1A19_RS01915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H1A19_RS01920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1A19_RS01920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1A19_RS01930	COG0515	serine threonine protein kinase
H1A19_RS01930	COG2815	serine threonine protein kinase
H1A19_RS01940	COG4585	Histidine kinase
H1A19_RS01945	COG2197	response regulator
H1A19_RS01955	COG1098	S1 RNA binding domain
H1A19_RS01960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1A19_RS01965	COG1349	DNA-binding transcription factor activity
H1A19_RS01975	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1A19_RS01985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1A19_RS01990	COG1882	Formate acetyltransferase
H1A19_RS02010	COG1739	Uncharacterized protein family UPF0029
H1A19_RS02015	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H1A19_RS02020	COG1040	competence protein
H1A19_RS02055	COG0527	aspartate kinase activity
H1A19_RS02060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1A19_RS02065	COG1024	Enoyl-CoA hydratase
H1A19_RS02075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1A19_RS02085	COG2070	2-Nitropropane dioxygenase
H1A19_RS02090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1A19_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
H1A19_RS02100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1A19_RS02115	COG0439	Biotin carboxylase
H1A19_RS02135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H1A19_RS02150	COG3716	PTS system mannose fructose sorbose family IID component
H1A19_RS02155	COG3715	PTS system
H1A19_RS02165	COG0561	phosphatase activity
H1A19_RS02180	COG2252	PERMEase
H1A19_RS02185	COG0802	atpase or kinase
H1A19_RS02195	COG1316	TRANSCRIPTIONal
H1A19_RS02205	COG0537	adenosine 5'-monophosphoramidase activity
H1A19_RS02220	COG1131	(ABC) transporter
H1A19_RS02225	COG4473	ABC transporter
H1A19_RS02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1A19_RS02250	COG0195	Participates in both transcription termination and antitermination
H1A19_RS02255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H1A19_RS02265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H1A19_RS02270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H1A19_RS02295	COG2860	membrane
H1A19_RS02305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1A19_RS02305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1A19_RS02310	COG1832	CoA-binding protein
H1A19_RS02330	COG5002	protein histidine kinase activity
H1A19_RS02350	COG1268	BioY protein
H1A19_RS02355	COG1234	tRNA 3'-trailer cleavage
H1A19_RS02370	COG0166	Belongs to the GPI family
H1A19_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1A19_RS02380	COG0705	Rhomboid family
H1A19_RS02380	COG0457	Tetratricopeptide repeat
H1A19_RS02385	COG1744	ABC transporter substrate-binding protein PnrA-like
H1A19_RS02390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1A19_RS02475	COG2153	protein acetylation
H1A19_RS02485	COG1442	glycosyl transferase family 8
H1A19_RS02485	COG1216	Glycosyl transferase, family 2
H1A19_RS02525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1A19_RS02535	COG0789	Transcriptional regulator
H1A19_RS02540	COG1063	alcohol dehydrogenase
H1A19_RS02545	COG0656	L-ascorbic acid biosynthetic process
H1A19_RS02600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1A19_RS02615	COG0673	inositol 2-dehydrogenase activity
H1A19_RS02625	COG3328	transposase activity
H1A19_RS02630	COG2315	Protein conserved in bacteria
H1A19_RS02645	COG0742	ribosomal rna small subunit methyltransferase
H1A19_RS02660	COG3480	Lon protease (S16) C-terminal proteolytic domain
H1A19_RS02670	COG4470	Protein conserved in bacteria
H1A19_RS02685	COG1132	(ABC) transporter
H1A19_RS02690	COG1132	(ABC) transporter
H1A19_RS02695	COG0512	Glutamine amidotransferase of anthranilate synthase
H1A19_RS02700	COG1268	BioY protein
H1A19_RS02715	COG0183	Belongs to the thiolase family
H1A19_RS02725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1A19_RS02740	COG1940	carbohydrate kinase activity
H1A19_RS02745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1A19_RS02785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1A19_RS02795	COG0762	integral membrane protein
H1A19_RS02800	COG2302	S4 RNA-binding domain
H1A19_RS02805	COG3599	regulation of cell shape
H1A19_RS02820	COG0494	nUDIX hydrolase
H1A19_RS02825	COG0542	response to heat
H1A19_RS02830	COG4703	Protein of unknown function (DUF1797)
H1A19_RS02835	COG0765	amino acid transport
H1A19_RS02840	COG1126	abc transporter atp-binding protein
H1A19_RS02845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1A19_RS02855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1A19_RS02865	COG1722	exodeoxyribonuclease VII activity
H1A19_RS02875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H1A19_RS02880	COG1438	arginine binding
H1A19_RS02885	COG0497	DNA recombination
H1A19_RS02890	COG1307	EDD domain protein, DegV family
H1A19_RS02895	COG2755	lipolytic protein G-D-S-L family
H1A19_RS02940	COG1078	dGTPase activity
H1A19_RS02965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1A19_RS02975	COG2884	Cell division ATP-binding protein ftsE
H1A19_RS02980	COG2177	Part of the ABC transporter FtsEX involved in
H1A19_RS03000	COG1199	ATP-dependent helicase activity
H1A19_RS03000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1A19_RS03005	COG0436	Aminotransferase
H1A19_RS03010	COG0017	Asparaginyl-tRNA synthetase
H1A19_RS03030	COG1660	Displays ATPase and GTPase activities
H1A19_RS03055	COG0254	rRNA binding
H1A19_RS03060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H1A19_RS03065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1A19_RS03070	COG0716	FMN binding
H1A19_RS03075	COG1605	Chorismate mutase
H1A19_RS03075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H1A19_RS03080	COG0038	chloride channel
H1A19_RS03090	COG0335	large ribosomal subunit rRNA binding
H1A19_RS03100	COG0582	viral genome integration into host DNA
H1A19_RS03295	COG3728	DNA packaging
H1A19_RS03295	COG5484	DNA packaging
H1A19_RS03465	COG1136	(ABC) transporter
H1A19_RS03480	COG5002	protein histidine kinase activity
H1A19_RS03500	COG0772	Belongs to the SEDS family
H1A19_RS03520	COG0560	Phosphoserine phosphatase
H1A19_RS03535	COG5433	transposase activity
H1A19_RS03540	COG0148	phosphopyruvate hydratase activity
H1A19_RS03560	COG1316	TRANSCRIPTIONal
H1A19_RS03605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1A19_RS03605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1A19_RS03655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H1A19_RS03715	COG4695	Portal protein
H1A19_RS03720	COG0740	serine-type endopeptidase activity
H1A19_RS03780	COG5433	transposase activity
H1A19_RS03805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1A19_RS03830	COG3700	Belongs to the class B bacterial acid phosphatase family
H1A19_RS03920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1A19_RS03925	COG4555	ABC transporter
H1A19_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
H1A19_RS03955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1A19_RS03960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H1A19_RS03980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H1A19_RS03985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1A19_RS04005	COG3064	Membrane
H1A19_RS04005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1A19_RS04030	COG3590	peptidase
H1A19_RS04035	COG3590	peptidase
H1A19_RS04080	COG1136	(ABC) transporter
H1A19_RS04095	COG0586	Pfam SNARE associated Golgi protein
H1A19_RS04100	COG4619	ABC transporter
H1A19_RS04105	COG0390	transport system, permease component
H1A19_RS04115	COG0583	DNA-binding transcription factor activity
H1A19_RS04125	COG5433	transposase activity
H1A19_RS04140	COG2211	Major facilitator Superfamily
H1A19_RS04150	COG3250	beta-galactosidase activity
H1A19_RS04155	COG2186	Transcriptional regulator
H1A19_RS04160	COG0800	Aldolase
H1A19_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
H1A19_RS04195	COG1609	Transcriptional regulator
H1A19_RS04210	COG0438	transferase activity, transferring glycosyl groups
H1A19_RS04235	COG0765	amino acid transport
H1A19_RS04240	COG0765	amino acid transport
H1A19_RS04245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1A19_RS04250	COG1126	abc transporter atp-binding protein
H1A19_RS04255	COG0745	RESPONSE REGULATOR receiver
H1A19_RS04260	COG5002	protein histidine kinase activity
H1A19_RS04265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1A19_RS04270	COG2832	Protein of unknown function (DUF454)
H1A19_RS04280	COG1196	nuclear chromosome segregation
H1A19_RS04285	COG0561	phosphatase activity
H1A19_RS04290	COG0561	phosphatase activity
H1A19_RS04295	COG0552	protein localization to endoplasmic reticulum
H1A19_RS04300	COG3689	TIGRFAM TIGR03943 family protein
H1A19_RS04305	COG0701	Predicted permease
H1A19_RS04320	COG2183	response to ionizing radiation
H1A19_RS04325	COG3091	SprT-like family
H1A19_RS04330	COG1983	PspC domain protein
H1A19_RS04370	COG4443	Transcriptional Coactivator p15 (PC4)
H1A19_RS04380	COG1914	H( )-stimulated, divalent metal cation uptake system
H1A19_RS04395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1A19_RS04395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1A19_RS04420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1A19_RS04445	COG1164	Oligoendopeptidase f
H1A19_RS04455	COG0772	Belongs to the SEDS family
H1A19_RS04475	COG0768	penicillin binding
H1A19_RS04490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1A19_RS04495	COG2223	nitrite transmembrane transporter activity
H1A19_RS04520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1A19_RS04525	COG2011	ABC-type metal ion transport system permease component
H1A19_RS04530	COG1464	Belongs to the NlpA lipoprotein family
H1A19_RS04535	COG0513	Belongs to the DEAD box helicase family
H1A19_RS04545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H1A19_RS04550	COG0204	Acyl-transferase
H1A19_RS04555	COG1555	photosystem II stabilization
H1A19_RS04555	COG1596	polysaccharide export
H1A19_RS04560	COG0658	competence protein
H1A19_RS04560	COG2333	competence protein COMEC
H1A19_RS04565	COG0561	phosphatase activity
H1A19_RS04605	COG0438	transferase activity, transferring glycosyl groups
H1A19_RS04625	COG3104	oligopeptide transport
H1A19_RS04630	COG3833	ABC-type maltose transport systems, permease component
H1A19_RS04635	COG1175	transmembrane transport
H1A19_RS04645	COG1609	Transcriptional regulator
H1A19_RS04650	COG1640	4-alpha-glucanotransferase
H1A19_RS04655	COG0058	SHG alpha-glucan phosphorylase activity
H1A19_RS04660	COG2271	Major facilitator Superfamily
H1A19_RS04680	COG0004	ammonium transporteR
H1A19_RS04685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1A19_RS04700	COG1970	mechanosensitive ion channel activity
H1A19_RS04705	COG0358	DNA primase activity
H1A19_RS04710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1A19_RS04715	COG2151	metal-sulfur cluster biosynthetic enzyme
H1A19_RS04720	COG1091	dTDP-4-dehydrorhamnose reductase activity
H1A19_RS04730	COG1215	transferase activity, transferring glycosyl groups
H1A19_RS04735	COG0463	Glycosyl transferase, family 2
H1A19_RS04750	COG3475	LICD family
H1A19_RS04790	COG0297	glycogen (starch) synthase activity
H1A19_RS04825	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H1A19_RS04830	COG0671	phosphoesterase, PA-phosphatase related
H1A19_RS04835	COG1242	4 iron, 4 sulfur cluster binding
H1A19_RS04840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1A19_RS04845	COG1253	flavin adenine dinucleotide binding
H1A19_RS04850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1A19_RS04865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1A19_RS04870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1A19_RS04875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1A19_RS04880	COG1120	ATPase activity
H1A19_RS04890	COG2244	polysaccharide biosynthetic process
H1A19_RS04920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H1A19_RS04930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H1A19_RS04935	COG1368	sulfuric ester hydrolase activity
H1A19_RS04940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H1A19_RS04965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1A19_RS04975	COG1104	cysteine desulfurase activity
H1A19_RS05000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H1A19_RS05005	COG0583	DNA-binding transcription factor activity
H1A19_RS05015	COG0564	pseudouridine synthase activity
H1A19_RS05025	COG0505	Belongs to the CarA family
H1A19_RS05035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1A19_RS05040	COG1136	(ABC) transporter
H1A19_RS05045	COG0577	efflux transmembrane transporter activity
H1A19_RS05050	COG0228	four-way junction DNA binding
H1A19_RS05055	COG1837	Belongs to the UPF0109 family
H1A19_RS05105	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1A19_RS05105	COG1388	LysM domain
H1A19_RS05110	COG1349	DNA-binding transcription factor activity
H1A19_RS05115	COG1105	Belongs to the carbohydrate kinase PfkB family
H1A19_RS05120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1A19_RS05120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1A19_RS05120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1A19_RS05150	COG0488	(ABC) transporter
H1A19_RS05165	COG1132	(ABC) transporter
H1A19_RS05175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1A19_RS05180	COG0242	peptide deformylase activity
H1A19_RS05185	COG0737	Belongs to the 5'-nucleotidase family
H1A19_RS05200	COG1132	(ABC) transporter
H1A19_RS05205	COG2357	RelA SpoT domain protein
H1A19_RS05210	COG0745	RESPONSE REGULATOR receiver
H1A19_RS05255	COG1272	protein, Hemolysin III
H1A19_RS05270	COG3425	synthase
H1A19_RS05280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1A19_RS05340	COG2176	DNA-directed DNA polymerase activity
H1A19_RS05360	COG5433	transposase activity
H1A19_RS05365	COG0803	Belongs to the bacterial solute-binding protein 9 family
H1A19_RS05405	COG0534	Mate efflux family protein
H1A19_RS05430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1A19_RS05435	COG1573	uracil-dna glycosylase
H1A19_RS05445	COG1523	belongs to the glycosyl hydrolase 13 family
H1A19_RS05480	COG0300	oxidoreductase activity
H1A19_RS05485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H1A19_RS05485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1A19_RS05495	COG5433	transposase activity
H1A19_RS05510	COG2384	SAM-dependent methyltransferase
H1A19_RS05520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1A19_RS05525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H1A19_RS05535	COG0135	phosphoribosylanthranilate isomerase activity
H1A19_RS05540	COG1088	dTDP-glucose 4,6-dehydratase activity
H1A19_RS05550	COG5433	transposase activity
H1A19_RS05560	COG1051	belongs to the nudix hydrolase family
H1A19_RS05570	COG0628	permease
H1A19_RS05575	COG0457	Tetratricopeptide repeat
H1A19_RS05580	COG0028	Belongs to the TPP enzyme family
H1A19_RS05585	COG3527	Alpha-acetolactate decarboxylase
H1A19_RS05590	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H1A19_RS05605	COG3842	ATPase activity
H1A19_RS05610	COG5433	transposase activity
H1A19_RS05645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1A19_RS05670	COG1316	TRANSCRIPTIONal
H1A19_RS05690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1A19_RS05695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H1A19_RS05710	COG1216	Glycosyl transferase, family 2
H1A19_RS05710	COG1442	glycosyl transferase family 8
H1A19_RS05715	COG1216	Glycosyl transferase, family 2
H1A19_RS05715	COG1442	glycosyl transferase family 8
H1A19_RS05730	COG2089	acid synthase
H1A19_RS05745	COG2755	lipolytic protein G-D-S-L family
H1A19_RS05745	COG1083	cytidylyl-transferase
H1A19_RS05755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H1A19_RS05760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H1A19_RS05765	COG0187	DNA topoisomerase II activity
H1A19_RS05775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1A19_RS05795	COG0539	negative regulation of cytoplasmic translation
H1A19_RS05810	COG1346	cytolysis
H1A19_RS05820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1A19_RS05825	COG1115	amino acid carrier protein
H1A19_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
H1A19_RS05930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1A19_RS05935	COG0726	polysaccharide deacetylase
H1A19_RS05950	COG2962	Rard protein
H1A19_RS05955	COG0285	dihydrofolate synthase activity
H1A19_RS05975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1A19_RS05980	COG5433	transposase activity
H1A19_RS05985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1A19_RS05995	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1A19_RS06000	COG1177	transmembrane transport
H1A19_RS06010	COG0038	chloride channel
H1A19_RS06020	COG0561	phosphatase activity
H1A19_RS06035	COG0628	permease
H1A19_RS06055	COG1104	cysteine desulfurase activity
H1A19_RS06070	COG2357	RelA SpoT domain protein
H1A19_RS06080	COG0564	pseudouridine synthase activity
H1A19_RS06085	COG0280	phosphate acetyltransferase
H1A19_RS06090	COG4221	oxidoreductase activity
H1A19_RS06105	COG0477	Major facilitator Superfamily
H1A19_RS06120	COG2233	PERMEase
H1A19_RS06130	COG3976	FMN-binding domain protein
H1A19_RS06130	COG0431	NADPH-dependent FMN reductase
H1A19_RS06130	COG1053	succinate dehydrogenase
H1A19_RS06145	COG1942	4-Oxalocrotonate Tautomerase
H1A19_RS06160	COG2890	protein-(glutamine-N5) methyltransferase activity
H1A19_RS06190	COG1132	(ABC) transporter
H1A19_RS06205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1A19_RS06210	COG4684	Psort location CytoplasmicMembrane, score
H1A19_RS06215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1A19_RS06225	COG0095	Lipoate-protein ligase
H1A19_RS06265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1A19_RS06275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1A19_RS06285	COG0488	(ABC) transporter
H1A19_RS06300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H1A19_RS06305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H1A19_RS06355	COG3275	phosphorelay sensor kinase activity
H1A19_RS06360	COG3279	Response regulator of the LytR AlgR family
H1A19_RS06365	COG1966	Carbon starvation protein
H1A19_RS06370	COG1376	ErfK ybiS ycfS ynhG family protein
H1A19_RS06375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1A19_RS06385	COG0110	maltose O-acetyltransferase activity
H1A19_RS06390	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1A19_RS06395	COG4605	iron ion homeostasis
H1A19_RS06400	COG4604	ABC transporter, ATP-binding protein
H1A19_RS06405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H1A19_RS06410	COG0758	DNA mediated transformation
H1A19_RS06415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1A19_RS06420	COG1136	(ABC) transporter
H1A19_RS06450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1A19_RS06455	COG0196	riboflavin kinase activity
H1A19_RS06470	COG0483	inositol monophosphate 1-phosphatase activity
H1A19_RS06475	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H1A19_RS06475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1A19_RS06485	COG0573	inorganic phosphate transmembrane transporter activity
H1A19_RS06490	COG0581	inorganic phosphate transmembrane transporter activity
H1A19_RS06495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1A19_RS06500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1A19_RS06505	COG0704	Plays a role in the regulation of phosphate uptake
H1A19_RS06515	COG0745	RESPONSE REGULATOR receiver
H1A19_RS06520	COG5002	protein histidine kinase activity
H1A19_RS06525	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H1A19_RS06530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1A19_RS06545	COG4166	transmembrane transport
H1A19_RS06550	COG4974	Belongs to the 'phage' integrase family
H1A19_RS06555	COG5002	protein histidine kinase activity
H1A19_RS06560	COG0745	RESPONSE REGULATOR receiver
H1A19_RS06570	COG1136	(ABC) transporter
H1A19_RS06585	COG1464	Belongs to the NlpA lipoprotein family
H1A19_RS06600	COG2188	Transcriptional regulator
H1A19_RS06625	COG0346	lactoylglutathione lyase activity
H1A19_RS06630	COG3764	Sortase (surface protein transpeptidase)
H1A19_RS06665	COG1744	ABC transporter substrate-binding protein PnrA-like
H1A19_RS06675	COG2813	Specifically methylates the guanine in position
H1A19_RS06680	COG1072	(Pantothenic acid kinase))
H1A19_RS06695	COG1126	abc transporter atp-binding protein
H1A19_RS06700	COG0765	amino acid transport
H1A19_RS06705	COG2824	Alkylphosphonate utilization operon protein PhnA
H1A19_RS06710	COG5433	transposase activity
H1A19_RS06725	COG0469	pyruvate kinase activity
H1A19_RS06730	COG0205	6-phosphofructokinase activity
H1A19_RS06740	COG1725	Transcriptional regulator
H1A19_RS06745	COG1131	(ABC) transporter
H1A19_RS06765	COG1674	ftsk spoiiie
H1A19_RS06775	COG2946	Replication initiation factor
H1A19_RS06805	COG0741	lytic transglycosylase activity
H1A19_RS06805	COG0791	NLP P60 protein
H1A19_RS07200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1A19_RS07210	COG0456	acetyltransferase
H1A19_RS07215	COG1418	mRNA catabolic process
H1A19_RS07225	COG5433	transposase activity
H1A19_RS07235	COG0481	GTPase activity
H1A19_RS07250	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H1A19_RS07255	COG1518	maintenance of DNA repeat elements
H1A19_RS07260	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
H1A19_RS07270	COG0647	UMP catabolic process
H1A19_RS07280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1A19_RS07305	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H1A19_RS07310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1A19_RS07315	COG3442	glutamine amidotransferase
H1A19_RS07320	COG0095	Lipoate-protein ligase
H1A19_RS07330	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1A19_RS07335	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1A19_RS07335	COG0022	dehydrogenase e1 component
H1A19_RS07340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1A19_RS07345	COG0488	(ABC) transporter
H1A19_RS07370	COG2321	neutral zinc metallopeptidase
H1A19_RS07455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H1A19_RS07470	COG1523	belongs to the glycosyl hydrolase 13 family
H1A19_RS07475	COG1597	lipid kinase activity
H1A19_RS07485	COG4708	membrane
H1A19_RS07490	COG2246	polysaccharide biosynthetic process
H1A19_RS07500	COG0024	Methionine aminopeptidase
H1A19_RS07505	COG4109	DRTGG domain
H1A19_RS07535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1A19_RS07545	COG1122	ATPase activity
H1A19_RS07550	COG4721	ABC-type cobalt transport system, permease component
H1A19_RS07580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H1A19_RS07580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H1A19_RS07590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1A19_RS07595	COG1956	GAF domain-containing protein
H1A19_RS07610	COG0726	polysaccharide deacetylase
H1A19_RS07615	COG1012	belongs to the aldehyde dehydrogenase family
H1A19_RS07630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1A19_RS07635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1A19_RS07640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1A19_RS07655	COG1476	TRANSCRIPTIONal
H1A19_RS07670	COG1442	glycosyl transferase family 8
H1A19_RS07685	COG4894	glucomannan catabolic process
H1A19_RS07695	COG4122	O-methyltransferase activity
H1A19_RS07700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1A19_RS07720	COG1187	pseudouridine synthase activity
H1A19_RS07725	COG0435	Glutathione S-transferase
H1A19_RS07730	COG0363	glucosamine-6-phosphate deaminase activity
H1A19_RS07745	COG1846	Transcriptional regulator
H1A19_RS07755	COG2610	gluconate transmembrane transporter activity
H1A19_RS07760	COG1929	Belongs to the glycerate kinase type-1 family
H1A19_RS07765	COG3835	regulator
H1A19_RS07775	COG1263	PTS System
H1A19_RS07775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS07775	COG2190	(PTS) system
H1A19_RS07780	COG3711	transcriptional antiterminator
H1A19_RS07785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1A19_RS07795	COG2226	methyltransferase
H1A19_RS07800	COG0657	acetylesterase activity
H1A19_RS07825	COG0488	(ABC) transporter
H1A19_RS07850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1A19_RS07880	COG0765	amino acid transport
H1A19_RS07885	COG1126	abc transporter atp-binding protein
H1A19_RS07910	COG2309	aminopeptidase activity
H1A19_RS07920	COG0154	amidase activity
H1A19_RS07925	COG1187	pseudouridine synthase activity
H1A19_RS07930	COG0656	L-ascorbic acid biosynthetic process
H1A19_RS07935	COG0778	Nitroreductase
H1A19_RS07940	COG0346	lactoylglutathione lyase activity
H1A19_RS07945	COG0463	Glycosyl transferase, family 2
H1A19_RS07950	COG1113	amino acid transport
H1A19_RS07955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H1A19_RS07960	COG0557	exoribonuclease II activity
H1A19_RS07975	COG2814	Major facilitator Superfamily
H1A19_RS07985	COG1131	(ABC) transporter
H1A19_RS07995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1A19_RS08000	COG1396	sequence-specific DNA binding
H1A19_RS08050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1A19_RS08055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H1A19_RS08075	COG1702	phosphate starvation-inducible protein PhoH
H1A19_RS08100	COG0233	cytoplasmic translational termination
H1A19_RS08115	COG0444	Belongs to the ABC transporter superfamily
H1A19_RS08120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1A19_RS08125	COG0601	transmembrane transport
H1A19_RS08130	COG0747	negative chemotaxis
H1A19_RS08135	COG0081	regulation of translation
H1A19_RS08155	COG1473	amidohydrolase
H1A19_RS08160	COG0583	DNA-binding transcription factor activity
H1A19_RS08175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1A19_RS08185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1A19_RS08210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1A19_RS08240	COG0673	inositol 2-dehydrogenase activity
H1A19_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
H1A19_RS08310	COG1114	Component of the transport system for branched-chain amino acids
H1A19_RS08315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1A19_RS08315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1A19_RS08330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1A19_RS08340	COG0708	Exodeoxyribonuclease III
H1A19_RS08345	COG1393	Belongs to the ArsC family
H1A19_RS08350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1A19_RS08355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1A19_RS08385	COG0470	DNA polymerase III
H1A19_RS08400	COG0517	IMP dehydrogenase activity
H1A19_RS08420	COG0559	Belongs to the binding-protein-dependent transport system permease family
H1A19_RS08440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H1A19_RS08445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1A19_RS08455	COG0531	amino acid
H1A19_RS08460	COG0569	domain protein
H1A19_RS08465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1A19_RS08475	COG1187	pseudouridine synthase activity
H1A19_RS08525	COG1827	regulation of RNA biosynthetic process
H1A19_RS08540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1A19_RS08545	COG1254	Belongs to the acylphosphatase family
H1A19_RS08555	COG0765	amino acid transport
H1A19_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1A19_RS08575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1A19_RS08605	COG1484	DNA-dependent DNA replication
H1A19_RS08620	COG5002	protein histidine kinase activity
H1A19_RS08625	COG0745	RESPONSE REGULATOR receiver
H1A19_RS08640	COG1704	LemA family
H1A19_RS08650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1A19_RS08655	COG0569	domain protein
H1A19_RS08680	COG1114	Component of the transport system for branched-chain amino acids
H1A19_RS08685	COG1063	alcohol dehydrogenase
H1A19_RS08710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1A19_RS08715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1A19_RS08720	COG0217	transcriptional regulatory protein
H1A19_RS08725	COG2376	Dihydroxyacetone kinase
H1A19_RS08730	COG1309	transcriptional regulator
H1A19_RS08735	COG2376	Dihydroxyacetone kinase
H1A19_RS08740	COG1461	Dihydroxyacetone kinase
H1A19_RS08745	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H1A19_RS08750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1A19_RS08760	COG0789	Transcriptional regulator
H1A19_RS08775	COG2226	methyltransferase
H1A19_RS08780	COG0799	negative regulation of ribosome biogenesis
H1A19_RS08790	COG1713	HD superfamily hydrolase involved in NAD metabolism
H1A19_RS08795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H1A19_RS08800	COG1534	Rna-binding protein
H1A19_RS08805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1A19_RS08810	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H1A19_RS08835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1A19_RS08835	COG0574	Belongs to the PEP-utilizing enzyme family
H1A19_RS08845	COG0517	IMP dehydrogenase activity
H1A19_RS08855	COG1335	isochorismatase
H1A19_RS08860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1A19_RS08865	COG0436	Aminotransferase
H1A19_RS08870	COG0589	response to stress
H1A19_RS08875	COG0561	phosphatase activity
H1A19_RS08880	COG0252	asparaginase activity
H1A19_RS08890	COG4989	oxidoreductase activity
H1A19_RS08895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1A19_RS08900	COG3942	CHAP domain
H1A19_RS08900	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1A19_RS08910	COG0736	holo-[acyl-carrier-protein] synthase activity
H1A19_RS08915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1A19_RS08925	COG1482	cell wall glycoprotein biosynthetic process
H1A19_RS08930	COG1940	carbohydrate kinase activity
H1A19_RS08935	COG2190	(PTS) system
H1A19_RS08935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS08935	COG1263	PTS System
H1A19_RS08940	COG1621	beta-fructofuranosidase activity
H1A19_RS08945	COG1609	Transcriptional regulator
H1A19_RS08950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1A19_RS08960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H1A19_RS08990	COG2131	deaminase
H1A19_RS09005	COG2814	Major facilitator Superfamily
H1A19_RS09030	COG0629	single-stranded DNA binding
H1A19_RS09035	COG0360	Binds together with S18 to 16S ribosomal RNA
H1A19_RS09040	COG1194	a g-specific adenine glycosylase
H1A19_RS09050	COG3118	belongs to the thioredoxin family
H1A19_RS09080	COG0681	Belongs to the peptidase S26 family
H1A19_RS09085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1A19_RS09100	COG1882	Formate acetyltransferase
H1A19_RS09105	COG3576	pyridoxamine 5-phosphate
H1A19_RS09110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1A19_RS09125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1A19_RS09135	COG2814	Major facilitator Superfamily
H1A19_RS09140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1A19_RS09155	COG0142	geranyltranstransferase activity
H1A19_RS09160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H1A19_RS09165	COG4988	ABC transporter
H1A19_RS09170	COG1294	oxidase, subunit
H1A19_RS09175	COG1271	oxidase subunit
H1A19_RS09180	COG1252	NADH dehydrogenase
H1A19_RS09195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H1A19_RS09200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1A19_RS09205	COG0789	Transcriptional regulator
H1A19_RS09220	COG2081	HI0933 family
H1A19_RS09245	COG0456	acetyltransferase
H1A19_RS09250	COG1214	PFAM Peptidase M22, glycoprotease
H1A19_RS09265	COG3942	CHAP domain
H1A19_RS09270	COG0174	glutamine synthetase
H1A19_RS09275	COG0789	Transcriptional regulator
H1A19_RS09290	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
H1A19_RS09315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1A19_RS09365	COG0084	hydrolase, TatD family'
H1A19_RS09390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H1A19_RS09395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1A19_RS09400	COG1696	Membrane protein involved in D-alanine export
H1A19_RS09420	COG0745	RESPONSE REGULATOR receiver
H1A19_RS09430	COG5433	transposase activity
H1A19_RS09450	COG4175	Glycine betaine
H1A19_RS09450	COG3448	diguanylate cyclase activity
H1A19_RS09455	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
H1A19_RS09475	COG1070	Carbohydrate kinase
H1A19_RS09485	COG3775	system Galactitol-specific IIC component
H1A19_RS09490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1A19_RS09500	COG1609	Transcriptional regulator
H1A19_RS09550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1A19_RS09580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1A19_RS09585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1A19_RS09590	COG1428	Deoxynucleoside kinase
H1A19_RS09600	COG0542	response to heat
H1A19_RS09605	COG4463	regulation of RNA biosynthetic process
H1A19_RS09615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H1A19_RS09625	COG0450	alkyl hydroperoxide reductase
H1A19_RS09640	COG0025	NhaP-type Na H and K H
H1A19_RS09650	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1A19_RS09655	COG3590	peptidase
H1A19_RS09680	COG1609	Transcriptional regulator
H1A19_RS09690	COG3716	PTS system mannose fructose sorbose family IID component
H1A19_RS09695	COG3715	PTS system
H1A19_RS09700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS09705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H1A19_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
H1A19_RS09750	COG2176	DNA-directed DNA polymerase activity
H1A19_RS09755	COG1388	LysM domain
H1A19_RS09755	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1A19_RS09770	COG4589	Belongs to the CDS family
H1A19_RS09775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1A19_RS09780	COG1862	Preprotein translocase
H1A19_RS09795	COG3493	citrate carrier protein
H1A19_RS09800	COG3290	protein histidine kinase activity
H1A19_RS09805	COG4565	transcriptional regulatory protein
H1A19_RS09810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1A19_RS09820	COG3842	ATPase activity
H1A19_RS09890	COG1490	D-aminoacyl-tRNA deacylase activity
H1A19_RS09900	COG0737	Belongs to the 5'-nucleotidase family
H1A19_RS09910	COG1363	Peptidase, m42
H1A19_RS09925	COG2207	Transcriptional regulator
H1A19_RS09925	COG4753	response regulator
H1A19_RS09930	COG2972	Histidine kinase
H1A19_RS09935	COG3716	PTS system mannose fructose sorbose family IID component
H1A19_RS09940	COG3715	PTS system
H1A19_RS09965	COG1131	(ABC) transporter
H1A19_RS09975	COG3279	Response regulator of the LytR AlgR family
H1A19_RS09985	COG1263	PTS System
H1A19_RS09985	COG2190	(PTS) system
H1A19_RS09985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1A19_RS09990	COG5002	protein histidine kinase activity
H1A19_RS09995	COG0745	RESPONSE REGULATOR receiver
H1A19_RS10005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1A19_RS10010	COG0581	inorganic phosphate transmembrane transporter activity
H1A19_RS10015	COG0573	inorganic phosphate transmembrane transporter activity
H1A19_RS10030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1A19_RS10045	COG0789	Transcriptional regulator
H1A19_RS10065	COG0456	acetyltransferase
H1A19_RS10070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1A19_RS10080	COG0582	viral genome integration into host DNA
H1A19_RS10120	COG0433	COG0433 Predicted ATPase
H1A19_RS10150	COG4115	mRNA cleavage
H1A19_RS10185	COG3620	sequence-specific DNA binding
H1A19_RS10200	COG1674	ftsk spoiiie
H1A19_RS10235	COG1914	H( )-stimulated, divalent metal cation uptake system
H1A19_RS10245	COG1131	(ABC) transporter
H1A19_RS10285	COG1131	(ABC) transporter
H1A19_RS10295	COG1396	sequence-specific DNA binding
H1A19_RS10305	COG1694	Mazg nucleotide pyrophosphohydrolase
H1A19_RS10335	COG0371	Dehydrogenase
H1A19_RS10345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1A19_RS10345	COG0646	methionine synthase
H1A19_RS10350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1A19_RS10360	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1A19_RS10370	COG0745	RESPONSE REGULATOR receiver
H1A19_RS10375	COG2205	protein histidine kinase activity
H1A19_RS10375	COG2770	Histidine kinase
H1A19_RS10385	COG0495	leucyl-tRNA aminoacylation
H1A19_RS10390	COG2814	Major facilitator Superfamily
H1A19_RS10395	COG4667	esterase of the alpha-beta hydrolase superfamily
H1A19_RS10400	COG1442	glycosyl transferase family 8
H1A19_RS10405	COG1442	glycosyl transferase family 8
H1A19_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1A19_RS10435	COG0564	pseudouridine synthase activity
H1A19_RS10455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1A19_RS10460	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H1A19_RS10480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H1A19_RS10485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1A19_RS10485	COG1116	anion transmembrane transporter activity
H1A19_RS10495	COG0561	phosphatase activity
H1A19_RS10500	COG2514	catechol 2,3-dioxygenase activity
H1A19_RS10510	COG0602	queuosine metabolic process
H1A19_RS10530	COG1328	CTP reductase activity
H1A19_RS10545	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1A19_RS10555	COG1393	Belongs to the ArsC family
H1A19_RS10560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H1A19_RS10570	COG2818	Glycosylase
H1A19_RS10585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1A19_RS10615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1A19_RS10620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1A19_RS10630	COG0124	histidyl-tRNA synthetase
H1A19_RS10640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H1A19_RS10650	COG0745	RESPONSE REGULATOR receiver
H1A19_RS10655	COG5002	protein histidine kinase activity
H1A19_RS10660	COG1288	antiporter activity
H1A19_RS10670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1A19_RS10675	COG3852	Histidine kinase
H1A19_RS10680	COG0784	Response regulator, receiver
H1A19_RS10685	COG1125	glycine betaine transport
H1A19_RS10685	COG0517	IMP dehydrogenase activity
H1A19_RS10690	COG1174	glycine betaine transport
H1A19_RS10695	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H1A19_RS10695	COG0392	lysyltransferase activity
H1A19_RS10705	COG3759	membrane
H1A19_RS10815	COG1396	sequence-specific DNA binding
H1A19_RS10820	COG2314	TM2 domain
H1A19_RS10830	COG0582	viral genome integration into host DNA
H1A19_RS10845	COG0305	Participates in initiation and elongation during chromosome replication
H1A19_RS10860	COG0445	tRNA wobble uridine modification
H1A19_RS10865	COG2095	MarC family integral membrane protein
H1A19_RS10870	COG0482	sulfurtransferase activity
H1A19_RS10875	COG1760	l-serine dehydratase
H1A19_RS10880	COG1760	l-serine dehydratase
H1A19_RS10885	COG0741	lytic transglycosylase activity
H1A19_RS10910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1A19_RS10915	COG0612	Peptidase, M16
H1A19_RS10920	COG0612	Peptidase, M16
H1A19_RS10925	COG2501	S4 domain
H1A19_RS10945	COG0517	IMP dehydrogenase activity
H1A19_RS10945	COG0516	GMP reductase activity
H1A19_RS10955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1A19_RS10970	COG0454	-acetyltransferase
H1A19_RS10975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1A19_RS11000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1A19_RS11005	COG0488	(ABC) transporter
H1A19_RS11010	COG4485	Bacterial membrane protein, YfhO
H1A19_RS11030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H1A19_RS11035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1A19_RS11040	COG1475	DNA binding