locus-tag	class	description
W903_RS00010	COG0592	DNA-directed DNA polymerase activity
W903_RS00015	COG1597	lipid kinase activity
W903_RS00030	COG0012	GTP binding
W903_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
W903_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
W903_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
W903_RS00260	COG0436	Aminotransferase
W903_RS00275	COG0416	fatty acid biosynthetic process
W903_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
W903_RS00285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
W903_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
W903_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
W903_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
W903_RS00320	COG0138	bifunctional purine biosynthesis protein purh
W903_RS00345	COG1175	transmembrane transport
W903_RS00350	COG0395	ABC-type sugar transport system, permease component
W903_RS00365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
W903_RS00375	COG3458	cephalosporin-C deacetylase activity
W903_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
W903_RS00410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
W903_RS00425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
W903_RS00435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
W903_RS00435	COG2755	lipolytic protein G-D-S-L family
W903_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
W903_RS00440	COG1454	alcohol dehydrogenase
W903_RS00445	COG1064	alcohol dehydrogenase
W903_RS00455	COG0534	Mate efflux family protein
W903_RS00565	COG0201	protein transport
W903_RS00570	COG0563	adenylate kinase activity
W903_RS00580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
W903_RS00590	COG0202	RNA polymerase activity
W903_RS00740	COG1705	Flagellar rod assembly protein muramidase FlgJ
W903_RS00755	COG0443	Heat shock 70 kDa protein
W903_RS00770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
W903_RS00780	COG0351	phosphomethylpyrimidine kinase
W903_RS00785	COG4720	Psort location CytoplasmicMembrane, score
W903_RS00795	COG0668	transmembrane transport
W903_RS00825	COG0756	dUTP diphosphatase activity
W903_RS00840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
W903_RS00845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
W903_RS00850	COG1879	ABC-type sugar transport system periplasmic component
W903_RS00855	COG1172	Belongs to the binding-protein-dependent transport system permease family
W903_RS00865	COG1869	D-ribose catabolic process
W903_RS00870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
W903_RS00875	COG1609	Transcriptional regulator
W903_RS00880	COG0577	efflux transmembrane transporter activity
W903_RS00885	COG1136	(ABC) transporter
W903_RS00890	COG0745	RESPONSE REGULATOR receiver
W903_RS00895	COG5002	protein histidine kinase activity
W903_RS00910	COG0191	fructose-bisphosphate aldolase activity
W903_RS00930	COG1461	Dihydroxyacetone kinase
W903_RS00950	COG1126	abc transporter atp-binding protein
W903_RS00955	COG0765	amino acid transport
W903_RS00975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
W903_RS00985	COG0719	Fe-S assembly protein
W903_RS00990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
W903_RS01000	COG0719	Fe-S assembly protein
W903_RS01005	COG1686	Belongs to the peptidase S11 family
W903_RS01010	COG1686	Belongs to the peptidase S11 family
W903_RS01015	COG4166	transmembrane transport
W903_RS01020	COG0601	transmembrane transport
W903_RS01025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
W903_RS01030	COG0444	Belongs to the ABC transporter superfamily
W903_RS01035	COG4608	Belongs to the ABC transporter superfamily
W903_RS01075	COG1121	(ABC) transporter
W903_RS01080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
W903_RS01090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
W903_RS01095	COG4499	WXG100 protein secretion system (Wss), protein YukC
W903_RS01095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
W903_RS01115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
W903_RS01120	COG1459	type II secretion system
W903_RS01170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
W903_RS01175	COG1363	Peptidase, m42
W903_RS01190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
W903_RS01195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
W903_RS01210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
W903_RS01230	COG1346	cytolysis
W903_RS01240	COG0601	transmembrane transport
W903_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
W903_RS01250	COG1122	ATPase activity
W903_RS01260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS01260	COG1263	PTS System
W903_RS01265	COG0366	Alpha amylase catalytic
W903_RS01270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
W903_RS01285	COG3959	Transketolase, thiamine diphosphate binding domain
W903_RS01290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
W903_RS01295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
W903_RS01315	COG1045	serine acetyltransferase
W903_RS01325	COG0215	cysteine-tRNA ligase activity
W903_RS01330	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
W903_RS01350	COG1476	TRANSCRIPTIONal
W903_RS01355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
W903_RS01405	COG1396	sequence-specific DNA binding
W903_RS01410	COG2814	Major facilitator Superfamily
W903_RS01420	COG1732	Glycine betaine
W903_RS01520	COG0519	Catalyzes the synthesis of GMP from XMP
W903_RS01565	COG1695	Transcriptional regulator
W903_RS01580	COG1755	Isoprenylcysteine carboxyl methyltransferase
W903_RS01620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
W903_RS01625	COG0446	pyridine nucleotide-disulphide oxidoreductase
W903_RS01645	COG1131	(ABC) transporter
W903_RS01655	COG1263	PTS System
W903_RS01655	COG2190	(PTS) system
W903_RS01655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS01660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
W903_RS01665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
W903_RS01670	COG0275	rRNA processing
W903_RS01680	COG0768	penicillin binding
W903_RS01690	COG0513	Belongs to the DEAD box helicase family
W903_RS01705	COG1126	abc transporter atp-binding protein
W903_RS01715	COG0492	ferredoxin-NADP+ reductase activity
W903_RS01720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
W903_RS01730	COG3579	cysteine-type endopeptidase activity
W903_RS01735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
W903_RS01755	COG0116	Belongs to the methyltransferase superfamily
W903_RS01765	COG1854	S-ribosylhomocysteine lyase activity
W903_RS01770	COG4372	Transposase
W903_RS01770	COG1418	mRNA catabolic process
W903_RS01775	COG1131	(ABC) transporter
W903_RS01785	COG4585	Histidine kinase
W903_RS01790	COG2197	response regulator
W903_RS01800	COG0194	GDP metabolic process
W903_RS01810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
W903_RS01815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
W903_RS01820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
W903_RS01820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
W903_RS01830	COG2815	serine threonine protein kinase
W903_RS01830	COG0515	serine threonine protein kinase
W903_RS01840	COG4585	Histidine kinase
W903_RS01845	COG2197	response regulator
W903_RS01855	COG1098	S1 RNA binding domain
W903_RS01860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
W903_RS01865	COG1349	DNA-binding transcription factor activity
W903_RS01875	COG1447	Phosphotransferase system cellobiose-specific component IIA
W903_RS01885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
W903_RS01890	COG1882	Formate acetyltransferase
W903_RS01910	COG1739	Uncharacterized protein family UPF0029
W903_RS01915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
W903_RS01920	COG1040	competence protein
W903_RS01955	COG0527	aspartate kinase activity
W903_RS01960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
W903_RS01965	COG1024	Enoyl-CoA hydratase
W903_RS01975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
W903_RS01985	COG2070	2-Nitropropane dioxygenase
W903_RS01990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
W903_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
W903_RS02000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
W903_RS02015	COG0439	Biotin carboxylase
W903_RS02035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
W903_RS02050	COG3716	PTS system mannose fructose sorbose family IID component
W903_RS02055	COG3715	PTS system
W903_RS02065	COG0561	phosphatase activity
W903_RS02080	COG2252	PERMEase
W903_RS02085	COG0802	atpase or kinase
W903_RS02095	COG1316	TRANSCRIPTIONal
W903_RS02105	COG0537	adenosine 5'-monophosphoramidase activity
W903_RS02115	COG1131	(ABC) transporter
W903_RS02120	COG4473	ABC transporter
W903_RS02130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
W903_RS02160	COG3620	sequence-specific DNA binding
W903_RS02285	COG3843	relaxase mobilization nuclease domain protein
W903_RS02305	COG0195	Participates in both transcription termination and antitermination
W903_RS02310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
W903_RS02320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
W903_RS02325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
W903_RS02350	COG2860	membrane
W903_RS02360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
W903_RS02360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
W903_RS02365	COG1832	CoA-binding protein
W903_RS02385	COG5002	protein histidine kinase activity
W903_RS02405	COG1268	BioY protein
W903_RS02410	COG1234	tRNA 3'-trailer cleavage
W903_RS02425	COG0166	Belongs to the GPI family
W903_RS02430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
W903_RS02435	COG0705	Rhomboid family
W903_RS02435	COG0457	Tetratricopeptide repeat
W903_RS02440	COG1744	ABC transporter substrate-binding protein PnrA-like
W903_RS02445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
W903_RS02460	COG0706	membrane insertase activity
W903_RS02530	COG2153	protein acetylation
W903_RS02540	COG1216	Glycosyl transferase, family 2
W903_RS02540	COG1442	glycosyl transferase family 8
W903_RS02580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
W903_RS02590	COG0789	Transcriptional regulator
W903_RS02595	COG1063	alcohol dehydrogenase
W903_RS02600	COG0656	L-ascorbic acid biosynthetic process
W903_RS02640	COG2226	methyltransferase
W903_RS02650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
W903_RS02655	COG3414	Phosphotransferase system galactitol-specific IIB component
W903_RS02660	COG3775	system Galactitol-specific IIC component
W903_RS02665	COG0235	Class ii aldolase
W903_RS02675	COG3775	system Galactitol-specific IIC component
W903_RS02680	COG3414	Phosphotransferase system galactitol-specific IIB component
W903_RS02685	COG2207	Transcriptional regulator
W903_RS02695	COG1175	transmembrane transport
W903_RS02700	COG0395	ABC-type sugar transport system, permease component
W903_RS02710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
W903_RS02720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
W903_RS02725	COG2017	converts alpha-aldose to the beta-anomer
W903_RS02745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
W903_RS02770	COG0673	inositol 2-dehydrogenase activity
W903_RS02780	COG2315	Protein conserved in bacteria
W903_RS02795	COG0742	ribosomal rna small subunit methyltransferase
W903_RS02810	COG3480	Lon protease (S16) C-terminal proteolytic domain
W903_RS02815	COG0737	Belongs to the 5'-nucleotidase family
W903_RS02820	COG4470	Protein conserved in bacteria
W903_RS02835	COG1132	(ABC) transporter
W903_RS02840	COG1132	(ABC) transporter
W903_RS02845	COG0512	Glutamine amidotransferase of anthranilate synthase
W903_RS02850	COG1268	BioY protein
W903_RS02855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
W903_RS02875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
W903_RS02890	COG1940	carbohydrate kinase activity
W903_RS02895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
W903_RS02900	COG1217	gtp-binding protein TYPA
W903_RS02935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
W903_RS02945	COG0762	integral membrane protein
W903_RS02950	COG2302	S4 RNA-binding domain
W903_RS02955	COG3599	regulation of cell shape
W903_RS02960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
W903_RS02970	COG0494	nUDIX hydrolase
W903_RS02975	COG0542	response to heat
W903_RS02980	COG4703	Protein of unknown function (DUF1797)
W903_RS02985	COG0765	amino acid transport
W903_RS02990	COG1126	abc transporter atp-binding protein
W903_RS02995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
W903_RS03005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
W903_RS03010	COG1570	exodeoxyribonuclease VII activity
W903_RS03015	COG1722	exodeoxyribonuclease VII activity
W903_RS03025	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
W903_RS03030	COG1438	arginine binding
W903_RS03035	COG0497	DNA recombination
W903_RS03040	COG1307	EDD domain protein, DegV family
W903_RS03045	COG2755	lipolytic protein G-D-S-L family
W903_RS03060	COG0582	viral genome integration into host DNA
W903_RS03075	COG1396	sequence-specific DNA binding
W903_RS03200	COG1783	phage Terminase large subunit
W903_RS03310	COG1705	Flagellar rod assembly protein muramidase FlgJ
W903_RS03360	COG1078	dGTPase activity
W903_RS03385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
W903_RS03395	COG2884	Cell division ATP-binding protein ftsE
W903_RS03400	COG2177	Part of the ABC transporter FtsEX involved in
W903_RS03420	COG1199	ATP-dependent helicase activity
W903_RS03420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
W903_RS03425	COG0436	Aminotransferase
W903_RS03430	COG0017	Asparaginyl-tRNA synthetase
W903_RS03450	COG1660	Displays ATPase and GTPase activities
W903_RS03475	COG0254	rRNA binding
W903_RS03480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
W903_RS03485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
W903_RS03490	COG0716	FMN binding
W903_RS03495	COG1605	Chorismate mutase
W903_RS03495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
W903_RS03500	COG0038	chloride channel
W903_RS03505	COG0335	large ribosomal subunit rRNA binding
W903_RS03540	COG1136	(ABC) transporter
W903_RS03555	COG5002	protein histidine kinase activity
W903_RS03570	COG0772	Belongs to the SEDS family
W903_RS03590	COG0560	Phosphoserine phosphatase
W903_RS03605	COG0148	phosphopyruvate hydratase activity
W903_RS03625	COG1316	TRANSCRIPTIONal
W903_RS03650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
W903_RS03655	COG4555	ABC transporter
W903_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
W903_RS03685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
W903_RS03690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
W903_RS03710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
W903_RS03715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
W903_RS03745	COG1136	(ABC) transporter
W903_RS03760	COG0586	Pfam SNARE associated Golgi protein
W903_RS03765	COG4619	ABC transporter
W903_RS03770	COG0390	transport system, permease component
W903_RS03780	COG0583	DNA-binding transcription factor activity
W903_RS03790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
W903_RS03795	COG2211	Major facilitator Superfamily
W903_RS03805	COG3250	beta-galactosidase activity
W903_RS03810	COG2186	Transcriptional regulator
W903_RS03815	COG0800	Aldolase
W903_RS03820	COG1904	glucuronate isomerase
W903_RS03825	COG1312	Catalyzes the dehydration of D-mannonate
W903_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
W903_RS03850	COG1609	Transcriptional regulator
W903_RS03865	COG0438	transferase activity, transferring glycosyl groups
W903_RS03890	COG0765	amino acid transport
W903_RS03895	COG0765	amino acid transport
W903_RS03900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
W903_RS03905	COG1126	abc transporter atp-binding protein
W903_RS03910	COG0745	RESPONSE REGULATOR receiver
W903_RS03915	COG5002	protein histidine kinase activity
W903_RS03920	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
W903_RS03925	COG2832	Protein of unknown function (DUF454)
W903_RS03935	COG1196	nuclear chromosome segregation
W903_RS03940	COG0561	phosphatase activity
W903_RS03945	COG0561	phosphatase activity
W903_RS03950	COG0552	protein localization to endoplasmic reticulum
W903_RS03955	COG3689	TIGRFAM TIGR03943 family protein
W903_RS03960	COG0701	Predicted permease
W903_RS03975	COG2183	response to ionizing radiation
W903_RS03980	COG3091	SprT-like family
W903_RS03985	COG1983	PspC domain protein
W903_RS04020	COG0826	peptidase U32
W903_RS04025	COG4443	Transcriptional Coactivator p15 (PC4)
W903_RS04035	COG1914	H( )-stimulated, divalent metal cation uptake system
W903_RS04050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
W903_RS04050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
W903_RS04075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
W903_RS04100	COG1164	Oligoendopeptidase f
W903_RS04110	COG0772	Belongs to the SEDS family
W903_RS04130	COG4974	Belongs to the 'phage' integrase family
W903_RS04135	COG0582	viral genome integration into host DNA
W903_RS04155	COG0768	penicillin binding
W903_RS04170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
W903_RS04175	COG2223	nitrite transmembrane transporter activity
W903_RS04200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
W903_RS04205	COG2011	ABC-type metal ion transport system permease component
W903_RS04210	COG1464	Belongs to the NlpA lipoprotein family
W903_RS04215	COG0513	Belongs to the DEAD box helicase family
W903_RS04225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
W903_RS04230	COG0204	Acyl-transferase
W903_RS04235	COG1596	polysaccharide export
W903_RS04235	COG1555	photosystem II stabilization
W903_RS04240	COG2333	competence protein COMEC
W903_RS04240	COG0658	competence protein
W903_RS04245	COG0561	phosphatase activity
W903_RS04250	COG1609	Transcriptional regulator
W903_RS04255	COG0657	acetylesterase activity
W903_RS04260	COG2226	methyltransferase
W903_RS04270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
W903_RS04275	COG3711	transcriptional antiterminator
W903_RS04280	COG2190	(PTS) system
W903_RS04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS04280	COG1263	PTS System
W903_RS04290	COG3835	regulator
W903_RS04295	COG1929	Belongs to the glycerate kinase type-1 family
W903_RS04300	COG2610	gluconate transmembrane transporter activity
W903_RS04310	COG1846	Transcriptional regulator
W903_RS04315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
W903_RS04325	COG0363	glucosamine-6-phosphate deaminase activity
W903_RS04330	COG0435	Glutathione S-transferase
W903_RS04335	COG1187	pseudouridine synthase activity
W903_RS04355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
W903_RS04360	COG4122	O-methyltransferase activity
W903_RS04370	COG4894	glucomannan catabolic process
W903_RS04385	COG1442	glycosyl transferase family 8
W903_RS04400	COG1476	TRANSCRIPTIONal
W903_RS04415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
W903_RS04420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
W903_RS04425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
W903_RS04440	COG1012	belongs to the aldehyde dehydrogenase family
W903_RS04445	COG0726	polysaccharide deacetylase
W903_RS04450	COG0513	Belongs to the DEAD box helicase family
W903_RS04460	COG1956	GAF domain-containing protein
W903_RS04465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
W903_RS04475	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
W903_RS04475	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
W903_RS04480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
W903_RS04505	COG4721	ABC-type cobalt transport system, permease component
W903_RS04510	COG1122	ATPase activity
W903_RS04520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
W903_RS04540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
W903_RS04550	COG4109	DRTGG domain
W903_RS04555	COG0024	Methionine aminopeptidase
W903_RS04570	COG4708	membrane
W903_RS04575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
W903_RS04580	COG1597	lipid kinase activity
W903_RS04585	COG1523	belongs to the glycosyl hydrolase 13 family
W903_RS04595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
W903_RS04600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
W903_RS04655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
W903_RS04680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
W903_RS04680	COG0072	phenylalanine-tRNA ligase activity
W903_RS04685	COG2321	neutral zinc metallopeptidase
W903_RS04695	COG1074	ATP-dependent DNA helicase activity
W903_RS04705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
W903_RS04715	COG0488	(ABC) transporter
W903_RS04720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
W903_RS04725	COG0022	dehydrogenase e1 component
W903_RS04725	COG0508	dehydrogenase complex catalyzes the overall conversion of
W903_RS04730	COG0508	dehydrogenase complex catalyzes the overall conversion of
W903_RS04740	COG0095	Lipoate-protein ligase
W903_RS04745	COG3442	glutamine amidotransferase
W903_RS04750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
W903_RS04755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
W903_RS04780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
W903_RS04790	COG0647	UMP catabolic process
W903_RS04800	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
W903_RS04805	COG1518	maintenance of DNA repeat elements
W903_RS04810	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
W903_RS04830	COG0481	GTPase activity
W903_RS04840	COG1418	mRNA catabolic process
W903_RS04845	COG0456	acetyltransferase
W903_RS04855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
W903_RS04880	COG1131	(ABC) transporter
W903_RS04885	COG1725	Transcriptional regulator
W903_RS04895	COG0205	6-phosphofructokinase activity
W903_RS04900	COG0469	pyruvate kinase activity
W903_RS04910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
W903_RS04915	COG2824	Alkylphosphonate utilization operon protein PhnA
W903_RS04920	COG0765	amino acid transport
W903_RS04925	COG1126	abc transporter atp-binding protein
W903_RS04940	COG1072	(Pantothenic acid kinase))
W903_RS04945	COG2813	Specifically methylates the guanine in position
W903_RS04955	COG1744	ABC transporter substrate-binding protein PnrA-like
W903_RS04960	COG3845	ABC transporter
W903_RS04965	COG4603	Belongs to the binding-protein-dependent transport system permease family
W903_RS04970	COG1079	Belongs to the binding-protein-dependent transport system permease family
W903_RS04990	COG3764	Sortase (surface protein transpeptidase)
W903_RS04995	COG0346	lactoylglutathione lyase activity
W903_RS05025	COG2946	Replication initiation factor
W903_RS05050	COG2188	Transcriptional regulator
W903_RS05055	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
W903_RS05065	COG1464	Belongs to the NlpA lipoprotein family
W903_RS05080	COG1136	(ABC) transporter
W903_RS05090	COG0745	RESPONSE REGULATOR receiver
W903_RS05095	COG5002	protein histidine kinase activity
W903_RS05100	COG4974	Belongs to the 'phage' integrase family
W903_RS05105	COG4166	transmembrane transport
W903_RS05120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
W903_RS05125	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
W903_RS05130	COG5002	protein histidine kinase activity
W903_RS05135	COG0745	RESPONSE REGULATOR receiver
W903_RS05145	COG0704	Plays a role in the regulation of phosphate uptake
W903_RS05150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
W903_RS05155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
W903_RS05160	COG0581	inorganic phosphate transmembrane transporter activity
W903_RS05165	COG0573	inorganic phosphate transmembrane transporter activity
W903_RS05175	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
W903_RS05175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
W903_RS05180	COG0483	inositol monophosphate 1-phosphatase activity
W903_RS05185	COG4476	Belongs to the UPF0223 family
W903_RS05195	COG0196	riboflavin kinase activity
W903_RS05200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
W903_RS05230	COG1136	(ABC) transporter
W903_RS05235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
W903_RS05240	COG0758	DNA mediated transformation
W903_RS05245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
W903_RS05250	COG4604	ABC transporter, ATP-binding protein
W903_RS05255	COG4605	iron ion homeostasis
W903_RS05260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
W903_RS05265	COG0110	maltose O-acetyltransferase activity
W903_RS05275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
W903_RS05295	COG2197	response regulator
W903_RS05310	COG1136	(ABC) transporter
W903_RS05350	COG1376	ErfK ybiS ycfS ynhG family protein
W903_RS05355	COG1966	Carbon starvation protein
W903_RS05360	COG3279	Response regulator of the LytR AlgR family
W903_RS05365	COG3275	phosphorelay sensor kinase activity
W903_RS05505	COG0505	Belongs to the CarA family
W903_RS05520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
W903_RS05535	COG0488	(ABC) transporter
W903_RS05545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
W903_RS05555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
W903_RS05605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
W903_RS05610	COG4684	Psort location CytoplasmicMembrane, score
W903_RS05615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
W903_RS05625	COG1132	(ABC) transporter
W903_RS05645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
W903_RS05655	COG2890	protein-(glutamine-N5) methyltransferase activity
W903_RS05670	COG1942	4-Oxalocrotonate Tautomerase
W903_RS05685	COG1053	succinate dehydrogenase
W903_RS05685	COG0431	NADPH-dependent FMN reductase
W903_RS05685	COG3976	FMN-binding domain protein
W903_RS05695	COG2233	PERMEase
W903_RS05710	COG0477	Major facilitator Superfamily
W903_RS05725	COG4221	oxidoreductase activity
W903_RS05730	COG0280	phosphate acetyltransferase
W903_RS05735	COG0564	pseudouridine synthase activity
W903_RS05745	COG2357	RelA SpoT domain protein
W903_RS05760	COG1104	cysteine desulfurase activity
W903_RS05780	COG0628	permease
W903_RS05785	COG2723	6-phospho-beta-galactosidase activity
W903_RS05795	COG0561	phosphatase activity
W903_RS05805	COG0038	chloride channel
W903_RS05815	COG1177	transmembrane transport
W903_RS05820	COG1176	ABC-type spermidine putrescine transport system, permease component I
W903_RS05830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
W903_RS05835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
W903_RS05855	COG0285	dihydrofolate synthase activity
W903_RS05860	COG2962	Rard protein
W903_RS05875	COG0726	polysaccharide deacetylase
W903_RS05880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
W903_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
W903_RS05960	COG2261	transglycosylase associated protein
W903_RS05980	COG1115	amino acid carrier protein
W903_RS05985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
W903_RS05995	COG1346	cytolysis
W903_RS06010	COG0539	negative regulation of cytoplasmic translation
W903_RS06030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
W903_RS06040	COG0187	DNA topoisomerase II activity
W903_RS06045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
W903_RS06050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
W903_RS06075	COG2089	acid synthase
W903_RS06090	COG1216	Glycosyl transferase, family 2
W903_RS06090	COG1442	glycosyl transferase family 8
W903_RS06095	COG1215	transferase activity, transferring glycosyl groups
W903_RS06100	COG0463	Glycosyl transferase, family 2
W903_RS06120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
W903_RS06145	COG1316	TRANSCRIPTIONal
W903_RS06170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
W903_RS06205	COG3842	ATPase activity
W903_RS06220	COG1293	RNA-binding protein homologous to eukaryotic snRNP
W903_RS06225	COG3527	Alpha-acetolactate decarboxylase
W903_RS06230	COG0028	Belongs to the TPP enzyme family
W903_RS06235	COG0457	Tetratricopeptide repeat
W903_RS06240	COG0628	permease
W903_RS06250	COG1051	belongs to the nudix hydrolase family
W903_RS06260	COG1088	dTDP-glucose 4,6-dehydratase activity
W903_RS06270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
W903_RS06275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
W903_RS06285	COG2384	SAM-dependent methyltransferase
W903_RS06305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
W903_RS06305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
W903_RS06310	COG0300	oxidoreductase activity
W903_RS06325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
W903_RS06355	COG1573	uracil-dna glycosylase
W903_RS06360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
W903_RS06385	COG0534	Mate efflux family protein
W903_RS06435	COG2040	homocysteine
W903_RS06440	COG0833	amino acid
W903_RS06475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
W903_RS06485	COG3425	synthase
W903_RS06500	COG1272	protein, Hemolysin III
W903_RS06545	COG0745	RESPONSE REGULATOR receiver
W903_RS06550	COG2357	RelA SpoT domain protein
W903_RS06570	COG0737	Belongs to the 5'-nucleotidase family
W903_RS06575	COG0242	peptide deformylase activity
W903_RS06580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
W903_RS06590	COG1132	(ABC) transporter
W903_RS06605	COG0488	(ABC) transporter
W903_RS06635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
W903_RS06635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
W903_RS06635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
W903_RS06640	COG1105	Belongs to the carbohydrate kinase PfkB family
W903_RS06645	COG1349	DNA-binding transcription factor activity
W903_RS06650	COG1705	Flagellar rod assembly protein muramidase FlgJ
W903_RS06650	COG1388	LysM domain
W903_RS06700	COG1837	Belongs to the UPF0109 family
W903_RS06705	COG0228	four-way junction DNA binding
W903_RS06710	COG0577	efflux transmembrane transporter activity
W903_RS06715	COG1136	(ABC) transporter
W903_RS06720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
W903_RS06730	COG0505	Belongs to the CarA family
W903_RS06740	COG0564	pseudouridine synthase activity
W903_RS06750	COG0583	DNA-binding transcription factor activity
W903_RS06755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
W903_RS06775	COG0301	tRNA thio-modification
W903_RS06780	COG1104	cysteine desulfurase activity
W903_RS06790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
W903_RS06795	COG3679	Belongs to the UPF0342 family
W903_RS06800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
W903_RS06805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
W903_RS06815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
W903_RS06820	COG1368	sulfuric ester hydrolase activity
W903_RS06825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
W903_RS06835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
W903_RS06840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
W903_RS06865	COG2244	polysaccharide biosynthetic process
W903_RS06870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
W903_RS06875	COG1120	ATPase activity
W903_RS06880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
W903_RS06885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
W903_RS06890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
W903_RS06905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
W903_RS06910	COG1253	flavin adenine dinucleotide binding
W903_RS06915	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
W903_RS06920	COG1242	4 iron, 4 sulfur cluster binding
W903_RS06925	COG0671	phosphoesterase, PA-phosphatase related
W903_RS06930	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
W903_RS06965	COG0297	glycogen (starch) synthase activity
W903_RS07005	COG3475	LICD family
W903_RS07020	COG0463	Glycosyl transferase, family 2
W903_RS07025	COG1215	transferase activity, transferring glycosyl groups
W903_RS07035	COG1091	dTDP-4-dehydrorhamnose reductase activity
W903_RS07040	COG2151	metal-sulfur cluster biosynthetic enzyme
W903_RS07045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
W903_RS07050	COG0358	DNA primase activity
W903_RS07055	COG1970	mechanosensitive ion channel activity
W903_RS07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
W903_RS07075	COG0004	ammonium transporteR
W903_RS07085	COG1054	Belongs to the UPF0176 family
W903_RS07095	COG2271	Major facilitator Superfamily
W903_RS07100	COG0058	SHG alpha-glucan phosphorylase activity
W903_RS07105	COG1640	4-alpha-glucanotransferase
W903_RS07110	COG1609	Transcriptional regulator
W903_RS07120	COG1175	transmembrane transport
W903_RS07125	COG3833	ABC-type maltose transport systems, permease component
W903_RS07130	COG3104	oligopeptide transport
W903_RS07150	COG0438	transferase activity, transferring glycosyl groups
W903_RS07155	COG0653	protein targeting
W903_RS07175	COG0201	protein transport
W903_RS07180	COG1442	glycosyl transferase family 8
W903_RS07185	COG1216	Glycosyl transferase, family 2
W903_RS07185	COG1442	glycosyl transferase family 8
W903_RS07190	COG1442	glycosyl transferase family 8
W903_RS07195	COG1442	glycosyl transferase family 8
W903_RS07195	COG1216	Glycosyl transferase, family 2
W903_RS07200	COG1442	glycosyl transferase family 8
W903_RS07235	COG0765	amino acid transport
W903_RS07240	COG1126	abc transporter atp-binding protein
W903_RS07265	COG2309	aminopeptidase activity
W903_RS07280	COG1187	pseudouridine synthase activity
W903_RS07285	COG0656	L-ascorbic acid biosynthetic process
W903_RS07290	COG0778	Nitroreductase
W903_RS07295	COG0346	lactoylglutathione lyase activity
W903_RS07300	COG0463	Glycosyl transferase, family 2
W903_RS07305	COG1113	amino acid transport
W903_RS07310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
W903_RS07315	COG0557	exoribonuclease II activity
W903_RS07325	COG2814	Major facilitator Superfamily
W903_RS07335	COG1131	(ABC) transporter
W903_RS07345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
W903_RS07350	COG1396	sequence-specific DNA binding
W903_RS07385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
W903_RS07390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
W903_RS07410	COG1702	phosphate starvation-inducible protein PhoH
W903_RS07435	COG0233	cytoplasmic translational termination
W903_RS07450	COG0444	Belongs to the ABC transporter superfamily
W903_RS07455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
W903_RS07460	COG0601	transmembrane transport
W903_RS07465	COG0747	negative chemotaxis
W903_RS07470	COG0081	regulation of translation
W903_RS07475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
W903_RS07485	COG1473	amidohydrolase
W903_RS07490	COG0583	DNA-binding transcription factor activity
W903_RS07500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
W903_RS07505	COG1674	ftsk spoiiie
W903_RS07510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
W903_RS07535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
W903_RS07565	COG0673	inositol 2-dehydrogenase activity
W903_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
W903_RS07625	COG1114	Component of the transport system for branched-chain amino acids
W903_RS07630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
W903_RS07630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
W903_RS07645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
W903_RS07655	COG0708	Exodeoxyribonuclease III
W903_RS07660	COG1393	Belongs to the ArsC family
W903_RS07665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
W903_RS07670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
W903_RS07680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
W903_RS07700	COG0470	DNA polymerase III
W903_RS07710	COG0517	IMP dehydrogenase activity
W903_RS07730	COG0559	Belongs to the binding-protein-dependent transport system permease family
W903_RS07750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
W903_RS07755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
W903_RS07765	COG0531	amino acid
W903_RS07770	COG0569	domain protein
W903_RS07775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
W903_RS07785	COG1187	pseudouridine synthase activity
W903_RS07820	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
W903_RS07835	COG1827	regulation of RNA biosynthetic process
W903_RS07850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
W903_RS07855	COG1254	Belongs to the acylphosphatase family
W903_RS07865	COG0765	amino acid transport
W903_RS07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
W903_RS07885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
W903_RS07915	COG1484	DNA-dependent DNA replication
W903_RS07930	COG5002	protein histidine kinase activity
W903_RS07935	COG0745	RESPONSE REGULATOR receiver
W903_RS07950	COG1704	LemA family
W903_RS07955	COG0357	Ribosomal RNA small subunit methyltransferase G
W903_RS07960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
W903_RS07965	COG0569	domain protein
W903_RS07990	COG1114	Component of the transport system for branched-chain amino acids
W903_RS07995	COG1063	alcohol dehydrogenase
W903_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
W903_RS08025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
W903_RS08030	COG0217	transcriptional regulatory protein
W903_RS08035	COG2376	Dihydroxyacetone kinase
W903_RS08040	COG1309	transcriptional regulator
W903_RS08045	COG2376	Dihydroxyacetone kinase
W903_RS08050	COG1461	Dihydroxyacetone kinase
W903_RS08055	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
W903_RS08060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
W903_RS08070	COG0789	Transcriptional regulator
W903_RS08085	COG2226	methyltransferase
W903_RS08090	COG0799	negative regulation of ribosome biogenesis
W903_RS08100	COG1713	HD superfamily hydrolase involved in NAD metabolism
W903_RS08105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
W903_RS08110	COG1534	Rna-binding protein
W903_RS08115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
W903_RS08120	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
W903_RS08145	COG0574	Belongs to the PEP-utilizing enzyme family
W903_RS08145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
W903_RS08155	COG0517	IMP dehydrogenase activity
W903_RS08165	COG1335	isochorismatase
W903_RS08170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
W903_RS08175	COG0436	Aminotransferase
W903_RS08180	COG0589	response to stress
W903_RS08185	COG0561	phosphatase activity
W903_RS08190	COG0252	asparaginase activity
W903_RS08200	COG4989	oxidoreductase activity
W903_RS08205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
W903_RS08210	COG1705	Flagellar rod assembly protein muramidase FlgJ
W903_RS08210	COG3942	CHAP domain
W903_RS08220	COG0736	holo-[acyl-carrier-protein] synthase activity
W903_RS08225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
W903_RS08235	COG1482	cell wall glycoprotein biosynthetic process
W903_RS08240	COG1940	carbohydrate kinase activity
W903_RS08245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS08245	COG2190	(PTS) system
W903_RS08245	COG1263	PTS System
W903_RS08250	COG1621	beta-fructofuranosidase activity
W903_RS08255	COG1609	Transcriptional regulator
W903_RS08260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
W903_RS08270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
W903_RS08285	COG2131	deaminase
W903_RS08290	COG0006	proline dipeptidase activity
W903_RS08300	COG2814	Major facilitator Superfamily
W903_RS08325	COG0629	single-stranded DNA binding
W903_RS08330	COG0360	Binds together with S18 to 16S ribosomal RNA
W903_RS08335	COG1194	a g-specific adenine glycosylase
W903_RS08345	COG3118	belongs to the thioredoxin family
W903_RS08370	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
W903_RS08375	COG0681	Belongs to the peptidase S26 family
W903_RS08380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
W903_RS08395	COG1882	Formate acetyltransferase
W903_RS08400	COG3576	pyridoxamine 5-phosphate
W903_RS08405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
W903_RS08420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
W903_RS08430	COG2814	Major facilitator Superfamily
W903_RS08435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
W903_RS08450	COG0142	geranyltranstransferase activity
W903_RS08455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
W903_RS08460	COG4988	ABC transporter
W903_RS08465	COG1294	oxidase, subunit
W903_RS08470	COG1271	oxidase subunit
W903_RS08475	COG1252	NADH dehydrogenase
W903_RS08490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
W903_RS08495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
W903_RS08535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
W903_RS08540	COG0456	acetyltransferase
W903_RS08545	COG1214	PFAM Peptidase M22, glycoprotease
W903_RS08560	COG3942	CHAP domain
W903_RS08565	COG0174	glutamine synthetase
W903_RS08570	COG0789	Transcriptional regulator
W903_RS08585	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
W903_RS08610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
W903_RS08635	COG1162	GTPase activity
W903_RS08660	COG0084	hydrolase, TatD family'
W903_RS08685	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
W903_RS08690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
W903_RS08695	COG1696	Membrane protein involved in D-alanine export
W903_RS08710	COG5002	protein histidine kinase activity
W903_RS08715	COG0745	RESPONSE REGULATOR receiver
W903_RS08725	COG3314	Sporulation integral membrane protein YlbJ
W903_RS08735	COG4175	Glycine betaine
W903_RS08735	COG3448	diguanylate cyclase activity
W903_RS08740	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
W903_RS08760	COG1070	Carbohydrate kinase
W903_RS08770	COG3775	system Galactitol-specific IIC component
W903_RS08775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
W903_RS08785	COG1609	Transcriptional regulator
W903_RS08835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
W903_RS08870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
W903_RS08875	COG1428	Deoxynucleoside kinase
W903_RS08885	COG0542	response to heat
W903_RS08890	COG4463	regulation of RNA biosynthetic process
W903_RS08900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
W903_RS08910	COG0450	alkyl hydroperoxide reductase
W903_RS08925	COG0025	NhaP-type Na H and K H
W903_RS08935	COG1619	proteins homologs of microcin C7 resistance protein MccF
W903_RS08940	COG3590	peptidase
W903_RS08965	COG1609	Transcriptional regulator
W903_RS08975	COG3716	PTS system mannose fructose sorbose family IID component
W903_RS08980	COG3715	PTS system
W903_RS08985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS08990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
W903_RS09000	COG1028	Short-chain dehydrogenase reductase Sdr
W903_RS09030	COG2176	DNA-directed DNA polymerase activity
W903_RS09035	COG1705	Flagellar rod assembly protein muramidase FlgJ
W903_RS09035	COG1388	LysM domain
W903_RS09050	COG4589	Belongs to the CDS family
W903_RS09055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
W903_RS09060	COG1862	Preprotein translocase
W903_RS09075	COG3493	citrate carrier protein
W903_RS09080	COG3290	protein histidine kinase activity
W903_RS09085	COG4565	transcriptional regulatory protein
W903_RS09090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
W903_RS09100	COG3842	ATPase activity
W903_RS09170	COG1490	D-aminoacyl-tRNA deacylase activity
W903_RS09180	COG0737	Belongs to the 5'-nucleotidase family
W903_RS09190	COG1363	Peptidase, m42
W903_RS09210	COG4753	response regulator
W903_RS09210	COG2207	Transcriptional regulator
W903_RS09215	COG2972	Histidine kinase
W903_RS09220	COG3716	PTS system mannose fructose sorbose family IID component
W903_RS09225	COG3715	PTS system
W903_RS09250	COG1131	(ABC) transporter
W903_RS09260	COG3279	Response regulator of the LytR AlgR family
W903_RS09270	COG1263	PTS System
W903_RS09270	COG2190	(PTS) system
W903_RS09270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
W903_RS09275	COG5002	protein histidine kinase activity
W903_RS09280	COG0745	RESPONSE REGULATOR receiver
W903_RS09290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
W903_RS09295	COG0581	inorganic phosphate transmembrane transporter activity
W903_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
W903_RS09315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
W903_RS09345	COG0456	acetyltransferase
W903_RS09350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
W903_RS09430	COG1131	(ABC) transporter
W903_RS09465	COG1131	(ABC) transporter
W903_RS09475	COG1396	sequence-specific DNA binding
W903_RS09485	COG1694	Mazg nucleotide pyrophosphohydrolase
W903_RS09500	COG2897	thiosulfate sulfurtransferase activity
W903_RS09510	COG2814	Major facilitator Superfamily
W903_RS09515	COG1309	transcriptional regulator
W903_RS09525	COG0371	Dehydrogenase
W903_RS09535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
W903_RS09535	COG0646	methionine synthase
W903_RS09540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
W903_RS09550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
W903_RS09565	COG0745	RESPONSE REGULATOR receiver
W903_RS09570	COG2770	Histidine kinase
W903_RS09570	COG2205	protein histidine kinase activity
W903_RS09585	COG2814	Major facilitator Superfamily
W903_RS09590	COG4667	esterase of the alpha-beta hydrolase superfamily
W903_RS09615	COG0564	pseudouridine synthase activity
W903_RS09635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
W903_RS09640	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
W903_RS09660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
W903_RS09665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
W903_RS09665	COG1116	anion transmembrane transporter activity
W903_RS09670	COG4120	Belongs to the binding-protein-dependent transport system permease family
W903_RS09680	COG0561	phosphatase activity
W903_RS09685	COG2514	catechol 2,3-dioxygenase activity
W903_RS09695	COG0602	queuosine metabolic process
W903_RS09715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
W903_RS09715	COG1328	CTP reductase activity
W903_RS09735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
W903_RS09745	COG1393	Belongs to the ArsC family
W903_RS09750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
W903_RS09755	COG1546	Belongs to the CinA family
W903_RS09755	COG1058	Belongs to the CinA family
W903_RS09760	COG2818	Glycosylase
W903_RS09795	COG0018	arginyl-trna synthetase
W903_RS09805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
W903_RS09810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
W903_RS09820	COG0124	histidyl-tRNA synthetase
W903_RS09830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
W903_RS09890	COG0745	RESPONSE REGULATOR receiver
W903_RS09895	COG5002	protein histidine kinase activity
W903_RS09900	COG1288	antiporter activity
W903_RS09910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
W903_RS09915	COG3852	Histidine kinase
W903_RS09920	COG0784	Response regulator, receiver
W903_RS09925	COG0517	IMP dehydrogenase activity
W903_RS09925	COG1125	glycine betaine transport
W903_RS09930	COG1174	glycine betaine transport
W903_RS09935	COG0392	lysyltransferase activity
W903_RS09935	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
W903_RS09945	COG3759	membrane
W903_RS09975	COG0305	Participates in initiation and elongation during chromosome replication
W903_RS09995	COG2095	MarC family integral membrane protein
W903_RS10000	COG0482	sulfurtransferase activity
W903_RS10005	COG1760	l-serine dehydratase
W903_RS10010	COG1760	l-serine dehydratase
W903_RS10015	COG0741	lytic transglycosylase activity
W903_RS10040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
W903_RS10045	COG0612	Peptidase, M16
W903_RS10050	COG0612	Peptidase, M16
W903_RS10055	COG2501	S4 domain
W903_RS10075	COG0517	IMP dehydrogenase activity
W903_RS10075	COG0516	GMP reductase activity
W903_RS10085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
W903_RS10100	COG0454	-acetyltransferase
W903_RS10115	COG0549	Belongs to the carbamate kinase family
W903_RS10130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
W903_RS10135	COG0488	(ABC) transporter
W903_RS10140	COG4485	Bacterial membrane protein, YfhO
W903_RS10160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
W903_RS10165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
W903_RS10170	COG1475	DNA binding