locus-tag	class	description
CUGBS08_RS00105	COG0436	Aminotransferase
CUGBS08_RS00125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS08_RS00135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUGBS08_RS00150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUGBS08_RS00185	COG1175	transmembrane transport
CUGBS08_RS00190	COG0395	ABC-type sugar transport system, permease component
CUGBS08_RS00205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUGBS08_RS00215	COG3458	cephalosporin-C deacetylase activity
CUGBS08_RS00230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CUGBS08_RS00245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUGBS08_RS00260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUGBS08_RS00270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CUGBS08_RS00270	COG2755	lipolytic protein G-D-S-L family
CUGBS08_RS00275	COG1454	alcohol dehydrogenase
CUGBS08_RS00275	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS08_RS00280	COG1064	alcohol dehydrogenase
CUGBS08_RS00290	COG0534	Mate efflux family protein
CUGBS08_RS00400	COG0201	protein transport
CUGBS08_RS00415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CUGBS08_RS00425	COG0202	RNA polymerase activity
CUGBS08_RS00565	COG2932	Transcriptional regulator
CUGBS08_RS00575	COG3561	AntA/AntB antirepressor
CUGBS08_RS00690	COG1783	phage Terminase large subunit
CUGBS08_RS00825	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS08_RS00840	COG0443	Heat shock 70 kDa protein
CUGBS08_RS00850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUGBS08_RS00860	COG0351	phosphomethylpyrimidine kinase
CUGBS08_RS00865	COG4720	Psort location CytoplasmicMembrane, score
CUGBS08_RS00875	COG0668	transmembrane transport
CUGBS08_RS00905	COG0756	dUTP diphosphatase activity
CUGBS08_RS00920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUGBS08_RS00935	COG1879	ABC-type sugar transport system periplasmic component
CUGBS08_RS00940	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUGBS08_RS00955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUGBS08_RS00960	COG1609	Transcriptional regulator
CUGBS08_RS00965	COG0577	efflux transmembrane transporter activity
CUGBS08_RS00970	COG1136	(ABC) transporter
CUGBS08_RS00975	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS00980	COG5002	protein histidine kinase activity
CUGBS08_RS00995	COG0191	fructose-bisphosphate aldolase activity
CUGBS08_RS01015	COG1461	Dihydroxyacetone kinase
CUGBS08_RS01055	COG1126	abc transporter atp-binding protein
CUGBS08_RS01060	COG0765	amino acid transport
CUGBS08_RS01080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUGBS08_RS01090	COG0719	Fe-S assembly protein
CUGBS08_RS01095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUGBS08_RS01105	COG0719	Fe-S assembly protein
CUGBS08_RS01110	COG1686	Belongs to the peptidase S11 family
CUGBS08_RS01115	COG1686	Belongs to the peptidase S11 family
CUGBS08_RS01120	COG4166	transmembrane transport
CUGBS08_RS01125	COG0601	transmembrane transport
CUGBS08_RS01130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS08_RS01135	COG0444	Belongs to the ABC transporter superfamily
CUGBS08_RS01140	COG4608	Belongs to the ABC transporter superfamily
CUGBS08_RS01180	COG1121	(ABC) transporter
CUGBS08_RS01185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUGBS08_RS01200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS08_RS01200	COG4499	WXG100 protein secretion system (Wss), protein YukC
CUGBS08_RS01225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUGBS08_RS01230	COG1459	type II secretion system
CUGBS08_RS01285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUGBS08_RS01290	COG1363	Peptidase, m42
CUGBS08_RS01305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUGBS08_RS01310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS08_RS01325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUGBS08_RS01345	COG1346	cytolysis
CUGBS08_RS01355	COG0601	transmembrane transport
CUGBS08_RS01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS08_RS01365	COG1122	ATPase activity
CUGBS08_RS01375	COG1263	PTS System
CUGBS08_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS08_RS01380	COG0366	Alpha amylase catalytic
CUGBS08_RS01385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS08_RS01400	COG3959	Transketolase, thiamine diphosphate binding domain
CUGBS08_RS01405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUGBS08_RS01410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUGBS08_RS01430	COG1045	serine acetyltransferase
CUGBS08_RS01445	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CUGBS08_RS01465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CUGBS08_RS01475	COG4974	Belongs to the 'phage' integrase family
CUGBS08_RS01580	COG1396	sequence-specific DNA binding
CUGBS08_RS01585	COG2814	Major facilitator Superfamily
CUGBS08_RS01595	COG1732	Glycine betaine
CUGBS08_RS01745	COG0519	Catalyzes the synthesis of GMP from XMP
CUGBS08_RS01790	COG1695	Transcriptional regulator
CUGBS08_RS01805	COG1755	Isoprenylcysteine carboxyl methyltransferase
CUGBS08_RS01845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS08_RS01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUGBS08_RS01870	COG1131	(ABC) transporter
CUGBS08_RS01880	COG1263	PTS System
CUGBS08_RS01880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS08_RS01880	COG2190	(PTS) system
CUGBS08_RS01885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CUGBS08_RS01905	COG0768	penicillin binding
CUGBS08_RS01915	COG0513	Belongs to the DEAD box helicase family
CUGBS08_RS01930	COG1126	abc transporter atp-binding protein
CUGBS08_RS01940	COG0492	ferredoxin-NADP+ reductase activity
CUGBS08_RS01945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CUGBS08_RS01955	COG3579	cysteine-type endopeptidase activity
CUGBS08_RS01960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS08_RS01985	COG0116	Belongs to the methyltransferase superfamily
CUGBS08_RS01995	COG1854	S-ribosylhomocysteine lyase activity
CUGBS08_RS02000	COG4372	Transposase
CUGBS08_RS02000	COG1418	mRNA catabolic process
CUGBS08_RS02005	COG1131	(ABC) transporter
CUGBS08_RS02015	COG4585	Histidine kinase
CUGBS08_RS02020	COG2197	response regulator
CUGBS08_RS02030	COG0194	GDP metabolic process
CUGBS08_RS02040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUGBS08_RS02045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CUGBS08_RS02050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUGBS08_RS02050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUGBS08_RS02060	COG2815	serine threonine protein kinase
CUGBS08_RS02060	COG0515	serine threonine protein kinase
CUGBS08_RS02070	COG4585	Histidine kinase
CUGBS08_RS02075	COG2197	response regulator
CUGBS08_RS02085	COG1098	S1 RNA binding domain
CUGBS08_RS02090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUGBS08_RS02095	COG1349	DNA-binding transcription factor activity
CUGBS08_RS02105	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUGBS08_RS02115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUGBS08_RS02120	COG1882	Formate acetyltransferase
CUGBS08_RS02140	COG1739	Uncharacterized protein family UPF0029
CUGBS08_RS02145	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CUGBS08_RS02150	COG1040	competence protein
CUGBS08_RS02185	COG0527	aspartate kinase activity
CUGBS08_RS02190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUGBS08_RS02195	COG1024	Enoyl-CoA hydratase
CUGBS08_RS02205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUGBS08_RS02215	COG2070	2-Nitropropane dioxygenase
CUGBS08_RS02220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUGBS08_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS08_RS02230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUGBS08_RS02245	COG0439	Biotin carboxylase
CUGBS08_RS02265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CUGBS08_RS02280	COG3716	PTS system mannose fructose sorbose family IID component
CUGBS08_RS02285	COG3715	PTS system
CUGBS08_RS02295	COG0561	phosphatase activity
CUGBS08_RS02310	COG2252	PERMEase
CUGBS08_RS02315	COG0802	atpase or kinase
CUGBS08_RS02325	COG1316	TRANSCRIPTIONal
CUGBS08_RS02335	COG0537	adenosine 5'-monophosphoramidase activity
CUGBS08_RS02350	COG1131	(ABC) transporter
CUGBS08_RS02355	COG4473	ABC transporter
CUGBS08_RS02365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUGBS08_RS02380	COG0195	Participates in both transcription termination and antitermination
CUGBS08_RS02385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CUGBS08_RS02395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CUGBS08_RS02400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CUGBS08_RS02425	COG2860	membrane
CUGBS08_RS02435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUGBS08_RS02435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUGBS08_RS02440	COG1832	CoA-binding protein
CUGBS08_RS02460	COG5002	protein histidine kinase activity
CUGBS08_RS02480	COG1268	BioY protein
CUGBS08_RS02485	COG1234	tRNA 3'-trailer cleavage
CUGBS08_RS02500	COG0166	Belongs to the GPI family
CUGBS08_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUGBS08_RS02510	COG0457	Tetratricopeptide repeat
CUGBS08_RS02510	COG0705	Rhomboid family
CUGBS08_RS02515	COG1744	ABC transporter substrate-binding protein PnrA-like
CUGBS08_RS02520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUGBS08_RS02535	COG0706	membrane insertase activity
CUGBS08_RS02595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUGBS08_RS02605	COG2153	protein acetylation
CUGBS08_RS02615	COG1442	glycosyl transferase family 8
CUGBS08_RS02615	COG1216	Glycosyl transferase, family 2
CUGBS08_RS02650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUGBS08_RS02660	COG0789	Transcriptional regulator
CUGBS08_RS02670	COG0656	L-ascorbic acid biosynthetic process
CUGBS08_RS02715	COG2226	methyltransferase
CUGBS08_RS02725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS08_RS02730	COG3414	Phosphotransferase system galactitol-specific IIB component
CUGBS08_RS02735	COG3775	system Galactitol-specific IIC component
CUGBS08_RS02740	COG0235	Class ii aldolase
CUGBS08_RS02750	COG3775	system Galactitol-specific IIC component
CUGBS08_RS02755	COG3414	Phosphotransferase system galactitol-specific IIB component
CUGBS08_RS02760	COG2207	Transcriptional regulator
CUGBS08_RS02780	COG1175	transmembrane transport
CUGBS08_RS02795	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CUGBS08_RS02805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUGBS08_RS02810	COG2017	converts alpha-aldose to the beta-anomer
CUGBS08_RS02870	COG1518	maintenance of DNA repeat elements
CUGBS08_RS02875	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CUGBS08_RS02880	COG0673	inositol 2-dehydrogenase activity
CUGBS08_RS02890	COG2315	Protein conserved in bacteria
CUGBS08_RS02905	COG0742	ribosomal rna small subunit methyltransferase
CUGBS08_RS02925	COG0737	Belongs to the 5'-nucleotidase family
CUGBS08_RS02930	COG4470	Protein conserved in bacteria
CUGBS08_RS02945	COG1132	(ABC) transporter
CUGBS08_RS02950	COG1132	(ABC) transporter
CUGBS08_RS02955	COG0512	Glutamine amidotransferase of anthranilate synthase
CUGBS08_RS02960	COG1268	BioY protein
CUGBS08_RS02965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CUGBS08_RS02985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUGBS08_RS03000	COG1940	carbohydrate kinase activity
CUGBS08_RS03005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUGBS08_RS03010	COG1217	gtp-binding protein TYPA
CUGBS08_RS03020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CUGBS08_RS03045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CUGBS08_RS03055	COG0762	integral membrane protein
CUGBS08_RS03060	COG2302	S4 RNA-binding domain
CUGBS08_RS03065	COG3599	regulation of cell shape
CUGBS08_RS03080	COG0494	nUDIX hydrolase
CUGBS08_RS03085	COG0542	response to heat
CUGBS08_RS03090	COG4703	Protein of unknown function (DUF1797)
CUGBS08_RS03095	COG0765	amino acid transport
CUGBS08_RS03100	COG1126	abc transporter atp-binding protein
CUGBS08_RS03105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUGBS08_RS03115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUGBS08_RS03120	COG1570	exodeoxyribonuclease VII activity
CUGBS08_RS03125	COG1722	exodeoxyribonuclease VII activity
CUGBS08_RS03135	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CUGBS08_RS03140	COG1438	arginine binding
CUGBS08_RS03145	COG0497	DNA recombination
CUGBS08_RS03150	COG1307	EDD domain protein, DegV family
CUGBS08_RS03155	COG2755	lipolytic protein G-D-S-L family
CUGBS08_RS03200	COG1078	dGTPase activity
CUGBS08_RS03225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUGBS08_RS03235	COG2884	Cell division ATP-binding protein ftsE
CUGBS08_RS03240	COG2177	Part of the ABC transporter FtsEX involved in
CUGBS08_RS03260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUGBS08_RS03260	COG1199	ATP-dependent helicase activity
CUGBS08_RS03265	COG0436	Aminotransferase
CUGBS08_RS03270	COG0017	Asparaginyl-tRNA synthetase
CUGBS08_RS03290	COG1660	Displays ATPase and GTPase activities
CUGBS08_RS03315	COG0254	rRNA binding
CUGBS08_RS03320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CUGBS08_RS03325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CUGBS08_RS03330	COG0716	FMN binding
CUGBS08_RS03335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CUGBS08_RS03335	COG1605	Chorismate mutase
CUGBS08_RS03340	COG0038	chloride channel
CUGBS08_RS03345	COG0335	large ribosomal subunit rRNA binding
CUGBS08_RS03380	COG1136	(ABC) transporter
CUGBS08_RS03395	COG5002	protein histidine kinase activity
CUGBS08_RS03410	COG0772	Belongs to the SEDS family
CUGBS08_RS03430	COG0560	Phosphoserine phosphatase
CUGBS08_RS03445	COG0148	phosphopyruvate hydratase activity
CUGBS08_RS03465	COG1316	TRANSCRIPTIONal
CUGBS08_RS03480	COG3700	Belongs to the class B bacterial acid phosphatase family
CUGBS08_RS03580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUGBS08_RS03585	COG4555	ABC transporter
CUGBS08_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS08_RS03615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS08_RS03620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUGBS08_RS03640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CUGBS08_RS03645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUGBS08_RS03665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUGBS08_RS03665	COG3064	Membrane
CUGBS08_RS03680	COG3590	peptidase
CUGBS08_RS03685	COG3590	peptidase
CUGBS08_RS03730	COG1136	(ABC) transporter
CUGBS08_RS03745	COG0586	Pfam SNARE associated Golgi protein
CUGBS08_RS03750	COG4619	ABC transporter
CUGBS08_RS03755	COG0390	transport system, permease component
CUGBS08_RS03765	COG0583	DNA-binding transcription factor activity
CUGBS08_RS03780	COG2211	Major facilitator Superfamily
CUGBS08_RS03790	COG3250	beta-galactosidase activity
CUGBS08_RS03795	COG2186	Transcriptional regulator
CUGBS08_RS03800	COG0800	Aldolase
CUGBS08_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS08_RS03835	COG1609	Transcriptional regulator
CUGBS08_RS03850	COG0438	transferase activity, transferring glycosyl groups
CUGBS08_RS03875	COG0765	amino acid transport
CUGBS08_RS03880	COG0765	amino acid transport
CUGBS08_RS03885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS08_RS03890	COG1126	abc transporter atp-binding protein
CUGBS08_RS03895	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS03900	COG5002	protein histidine kinase activity
CUGBS08_RS03905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CUGBS08_RS03910	COG2832	Protein of unknown function (DUF454)
CUGBS08_RS03920	COG1196	nuclear chromosome segregation
CUGBS08_RS03925	COG0561	phosphatase activity
CUGBS08_RS03930	COG0561	phosphatase activity
CUGBS08_RS03935	COG0552	protein localization to endoplasmic reticulum
CUGBS08_RS03940	COG3689	TIGRFAM TIGR03943 family protein
CUGBS08_RS03945	COG0701	Predicted permease
CUGBS08_RS03960	COG2183	response to ionizing radiation
CUGBS08_RS03965	COG3091	SprT-like family
CUGBS08_RS03970	COG1983	PspC domain protein
CUGBS08_RS04005	COG0826	peptidase U32
CUGBS08_RS04010	COG4443	Transcriptional Coactivator p15 (PC4)
CUGBS08_RS04020	COG1914	H( )-stimulated, divalent metal cation uptake system
CUGBS08_RS04035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUGBS08_RS04035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUGBS08_RS04060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUGBS08_RS04085	COG1164	Oligoendopeptidase f
CUGBS08_RS04095	COG0772	Belongs to the SEDS family
CUGBS08_RS04115	COG0768	penicillin binding
CUGBS08_RS04130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUGBS08_RS04135	COG2223	nitrite transmembrane transporter activity
CUGBS08_RS04165	COG2011	ABC-type metal ion transport system permease component
CUGBS08_RS04170	COG1464	Belongs to the NlpA lipoprotein family
CUGBS08_RS04175	COG0513	Belongs to the DEAD box helicase family
CUGBS08_RS04185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CUGBS08_RS04190	COG0204	Acyl-transferase
CUGBS08_RS04195	COG1555	photosystem II stabilization
CUGBS08_RS04195	COG1596	polysaccharide export
CUGBS08_RS04200	COG0658	competence protein
CUGBS08_RS04200	COG2333	competence protein COMEC
CUGBS08_RS04205	COG0561	phosphatase activity
CUGBS08_RS04210	COG1609	Transcriptional regulator
CUGBS08_RS04215	COG0657	acetylesterase activity
CUGBS08_RS04220	COG2226	methyltransferase
CUGBS08_RS04230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUGBS08_RS04235	COG3711	transcriptional antiterminator
CUGBS08_RS04240	COG1263	PTS System
CUGBS08_RS04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS08_RS04240	COG2190	(PTS) system
CUGBS08_RS04250	COG3835	regulator
CUGBS08_RS04255	COG1929	Belongs to the glycerate kinase type-1 family
CUGBS08_RS04260	COG2610	gluconate transmembrane transporter activity
CUGBS08_RS04270	COG1846	Transcriptional regulator
CUGBS08_RS04285	COG0363	glucosamine-6-phosphate deaminase activity
CUGBS08_RS04290	COG0435	Glutathione S-transferase
CUGBS08_RS04295	COG1187	pseudouridine synthase activity
CUGBS08_RS04315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CUGBS08_RS04320	COG4122	O-methyltransferase activity
CUGBS08_RS04330	COG4894	glucomannan catabolic process
CUGBS08_RS04345	COG1442	glycosyl transferase family 8
CUGBS08_RS04360	COG1476	TRANSCRIPTIONal
CUGBS08_RS04375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUGBS08_RS04380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUGBS08_RS04385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUGBS08_RS04400	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS08_RS04405	COG0726	polysaccharide deacetylase
CUGBS08_RS04420	COG1956	GAF domain-containing protein
CUGBS08_RS04425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUGBS08_RS04435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CUGBS08_RS04435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CUGBS08_RS04465	COG4721	ABC-type cobalt transport system, permease component
CUGBS08_RS04470	COG1122	ATPase activity
CUGBS08_RS04480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUGBS08_RS04510	COG4109	DRTGG domain
CUGBS08_RS04515	COG0024	Methionine aminopeptidase
CUGBS08_RS04525	COG2246	polysaccharide biosynthetic process
CUGBS08_RS04530	COG4708	membrane
CUGBS08_RS04540	COG1597	lipid kinase activity
CUGBS08_RS04545	COG1523	belongs to the glycosyl hydrolase 13 family
CUGBS08_RS04560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CUGBS08_RS04640	COG0072	phenylalanine-tRNA ligase activity
CUGBS08_RS04640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS08_RS04645	COG2321	neutral zinc metallopeptidase
CUGBS08_RS04670	COG0488	(ABC) transporter
CUGBS08_RS04675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CUGBS08_RS04680	COG0022	dehydrogenase e1 component
CUGBS08_RS04680	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUGBS08_RS04685	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUGBS08_RS04695	COG0095	Lipoate-protein ligase
CUGBS08_RS04700	COG3442	glutamine amidotransferase
CUGBS08_RS04705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUGBS08_RS04710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CUGBS08_RS04735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUGBS08_RS04745	COG0647	UMP catabolic process
CUGBS08_RS04755	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CUGBS08_RS04760	COG1518	maintenance of DNA repeat elements
CUGBS08_RS04765	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CUGBS08_RS04785	COG0481	GTPase activity
CUGBS08_RS04795	COG1418	mRNA catabolic process
CUGBS08_RS04800	COG0456	acetyltransferase
CUGBS08_RS04810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUGBS08_RS04840	COG1131	(ABC) transporter
CUGBS08_RS04845	COG1725	Transcriptional regulator
CUGBS08_RS04855	COG0205	6-phosphofructokinase activity
CUGBS08_RS04860	COG0469	pyruvate kinase activity
CUGBS08_RS04870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CUGBS08_RS04875	COG2824	Alkylphosphonate utilization operon protein PhnA
CUGBS08_RS04880	COG0765	amino acid transport
CUGBS08_RS04885	COG1126	abc transporter atp-binding protein
CUGBS08_RS04900	COG1072	(Pantothenic acid kinase))
CUGBS08_RS04905	COG2813	Specifically methylates the guanine in position
CUGBS08_RS04915	COG1744	ABC transporter substrate-binding protein PnrA-like
CUGBS08_RS04920	COG3845	ABC transporter
CUGBS08_RS04925	COG4603	Belongs to the binding-protein-dependent transport system permease family
CUGBS08_RS04930	COG1079	Belongs to the binding-protein-dependent transport system permease family
CUGBS08_RS04950	COG3764	Sortase (surface protein transpeptidase)
CUGBS08_RS04955	COG0346	lactoylglutathione lyase activity
CUGBS08_RS04985	COG2188	Transcriptional regulator
CUGBS08_RS05000	COG1464	Belongs to the NlpA lipoprotein family
CUGBS08_RS05015	COG1136	(ABC) transporter
CUGBS08_RS05025	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS05030	COG5002	protein histidine kinase activity
CUGBS08_RS05035	COG4974	Belongs to the 'phage' integrase family
CUGBS08_RS05040	COG4166	transmembrane transport
CUGBS08_RS05055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUGBS08_RS05060	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CUGBS08_RS05065	COG5002	protein histidine kinase activity
CUGBS08_RS05070	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS05080	COG0704	Plays a role in the regulation of phosphate uptake
CUGBS08_RS05085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUGBS08_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUGBS08_RS05095	COG0581	inorganic phosphate transmembrane transporter activity
CUGBS08_RS05100	COG0573	inorganic phosphate transmembrane transporter activity
CUGBS08_RS05110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CUGBS08_RS05110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUGBS08_RS05115	COG0483	inositol monophosphate 1-phosphatase activity
CUGBS08_RS05130	COG0196	riboflavin kinase activity
CUGBS08_RS05135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUGBS08_RS05165	COG1136	(ABC) transporter
CUGBS08_RS05170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CUGBS08_RS05175	COG0758	DNA mediated transformation
CUGBS08_RS05180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CUGBS08_RS05185	COG4604	ABC transporter, ATP-binding protein
CUGBS08_RS05190	COG4605	iron ion homeostasis
CUGBS08_RS05195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS08_RS05200	COG0110	maltose O-acetyltransferase activity
CUGBS08_RS05210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CUGBS08_RS05215	COG1376	ErfK ybiS ycfS ynhG family protein
CUGBS08_RS05220	COG1966	Carbon starvation protein
CUGBS08_RS05225	COG3279	Response regulator of the LytR AlgR family
CUGBS08_RS05230	COG3275	phosphorelay sensor kinase activity
CUGBS08_RS05335	COG0505	Belongs to the CarA family
CUGBS08_RS05345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CUGBS08_RS05365	COG0488	(ABC) transporter
CUGBS08_RS05385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUGBS08_RS05425	COG0095	Lipoate-protein ligase
CUGBS08_RS05435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUGBS08_RS05440	COG4684	Psort location CytoplasmicMembrane, score
CUGBS08_RS05445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUGBS08_RS05455	COG1132	(ABC) transporter
CUGBS08_RS05485	COG2890	protein-(glutamine-N5) methyltransferase activity
CUGBS08_RS05500	COG1942	4-Oxalocrotonate Tautomerase
CUGBS08_RS05515	COG0431	NADPH-dependent FMN reductase
CUGBS08_RS05515	COG1053	succinate dehydrogenase
CUGBS08_RS05515	COG3976	FMN-binding domain protein
CUGBS08_RS05525	COG2233	PERMEase
CUGBS08_RS05540	COG0477	Major facilitator Superfamily
CUGBS08_RS05555	COG4221	oxidoreductase activity
CUGBS08_RS05560	COG0280	phosphate acetyltransferase
CUGBS08_RS05565	COG0564	pseudouridine synthase activity
CUGBS08_RS05570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUGBS08_RS05575	COG2357	RelA SpoT domain protein
CUGBS08_RS05590	COG1104	cysteine desulfurase activity
CUGBS08_RS05600	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CUGBS08_RS05605	COG2003	Belongs to the UPF0758 family
CUGBS08_RS05610	COG0628	permease
CUGBS08_RS05615	COG2723	6-phospho-beta-galactosidase activity
CUGBS08_RS05625	COG0561	phosphatase activity
CUGBS08_RS05635	COG0038	chloride channel
CUGBS08_RS05645	COG1177	transmembrane transport
CUGBS08_RS05650	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUGBS08_RS05660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CUGBS08_RS05665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUGBS08_RS05685	COG0285	dihydrofolate synthase activity
CUGBS08_RS05690	COG2962	Rard protein
CUGBS08_RS05705	COG0726	polysaccharide deacetylase
CUGBS08_RS05710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUGBS08_RS05730	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS08_RS05810	COG2261	transglycosylase associated protein
CUGBS08_RS05835	COG1115	amino acid carrier protein
CUGBS08_RS05840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CUGBS08_RS05850	COG1346	cytolysis
CUGBS08_RS05865	COG0539	negative regulation of cytoplasmic translation
CUGBS08_RS05885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUGBS08_RS05895	COG0187	DNA topoisomerase II activity
CUGBS08_RS05900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CUGBS08_RS05915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CUGBS08_RS05925	COG2755	lipolytic protein G-D-S-L family
CUGBS08_RS05925	COG1083	cytidylyl-transferase
CUGBS08_RS05940	COG2089	acid synthase
CUGBS08_RS05955	COG1216	Glycosyl transferase, family 2
CUGBS08_RS05955	COG1442	glycosyl transferase family 8
CUGBS08_RS05960	COG1442	glycosyl transferase family 8
CUGBS08_RS05960	COG1216	Glycosyl transferase, family 2
CUGBS08_RS05975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUGBS08_RS06000	COG1316	TRANSCRIPTIONal
CUGBS08_RS06025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CUGBS08_RS06040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CUGBS08_RS06060	COG3842	ATPase activity
CUGBS08_RS06075	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CUGBS08_RS06080	COG3527	Alpha-acetolactate decarboxylase
CUGBS08_RS06085	COG0028	Belongs to the TPP enzyme family
CUGBS08_RS06090	COG0457	Tetratricopeptide repeat
CUGBS08_RS06095	COG0628	permease
CUGBS08_RS06105	COG1051	belongs to the nudix hydrolase family
CUGBS08_RS06110	COG5492	domain, Protein
CUGBS08_RS06115	COG1088	dTDP-glucose 4,6-dehydratase activity
CUGBS08_RS06125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CUGBS08_RS06130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUGBS08_RS06140	COG2384	SAM-dependent methyltransferase
CUGBS08_RS06160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUGBS08_RS06160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CUGBS08_RS06165	COG0300	oxidoreductase activity
CUGBS08_RS06180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUGBS08_RS06210	COG1573	uracil-dna glycosylase
CUGBS08_RS06215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUGBS08_RS06225	COG0584	glycerophosphoryl diester phosphodiesterase
CUGBS08_RS06230	COG0322	excinuclease ABC activity
CUGBS08_RS06240	COG0534	Mate efflux family protein
CUGBS08_RS06275	COG2801	Transposase and inactivated derivatives
CUGBS08_RS06285	COG0803	Belongs to the bacterial solute-binding protein 9 family
CUGBS08_RS06310	COG2176	DNA-directed DNA polymerase activity
CUGBS08_RS06320	COG4974	Belongs to the 'phage' integrase family
CUGBS08_RS06350	COG1674	ftsk spoiiie
CUGBS08_RS06390	COG2040	homocysteine
CUGBS08_RS06395	COG0833	amino acid
CUGBS08_RS06430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CUGBS08_RS06440	COG3425	synthase
CUGBS08_RS06455	COG1272	protein, Hemolysin III
CUGBS08_RS06500	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS06505	COG2357	RelA SpoT domain protein
CUGBS08_RS06510	COG1132	(ABC) transporter
CUGBS08_RS06525	COG0737	Belongs to the 5'-nucleotidase family
CUGBS08_RS06530	COG0242	peptide deformylase activity
CUGBS08_RS06535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUGBS08_RS06545	COG1132	(ABC) transporter
CUGBS08_RS06560	COG0488	(ABC) transporter
CUGBS08_RS06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS08_RS06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS08_RS06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS08_RS06595	COG1105	Belongs to the carbohydrate kinase PfkB family
CUGBS08_RS06600	COG1349	DNA-binding transcription factor activity
CUGBS08_RS06655	COG1837	Belongs to the UPF0109 family
CUGBS08_RS06660	COG0228	four-way junction DNA binding
CUGBS08_RS06665	COG0577	efflux transmembrane transporter activity
CUGBS08_RS06670	COG1136	(ABC) transporter
CUGBS08_RS06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUGBS08_RS06685	COG0505	Belongs to the CarA family
CUGBS08_RS06695	COG0564	pseudouridine synthase activity
CUGBS08_RS06705	COG0583	DNA-binding transcription factor activity
CUGBS08_RS06710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CUGBS08_RS06730	COG0301	tRNA thio-modification
CUGBS08_RS06735	COG1104	cysteine desulfurase activity
CUGBS08_RS06745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUGBS08_RS06750	COG3679	Belongs to the UPF0342 family
CUGBS08_RS06755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CUGBS08_RS06770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUGBS08_RS06775	COG1368	sulfuric ester hydrolase activity
CUGBS08_RS06780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CUGBS08_RS06790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CUGBS08_RS06795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CUGBS08_RS06820	COG2244	polysaccharide biosynthetic process
CUGBS08_RS06825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUGBS08_RS06830	COG1120	ATPase activity
CUGBS08_RS06835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CUGBS08_RS06840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS08_RS06845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS08_RS06860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUGBS08_RS06865	COG1253	flavin adenine dinucleotide binding
CUGBS08_RS06870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CUGBS08_RS06875	COG1242	4 iron, 4 sulfur cluster binding
CUGBS08_RS06880	COG0671	phosphoesterase, PA-phosphatase related
CUGBS08_RS06885	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CUGBS08_RS06920	COG0297	glycogen (starch) synthase activity
CUGBS08_RS06960	COG3475	LICD family
CUGBS08_RS06975	COG0463	Glycosyl transferase, family 2
CUGBS08_RS06980	COG1215	transferase activity, transferring glycosyl groups
CUGBS08_RS06990	COG1091	dTDP-4-dehydrorhamnose reductase activity
CUGBS08_RS06995	COG2151	metal-sulfur cluster biosynthetic enzyme
CUGBS08_RS07000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CUGBS08_RS07005	COG0358	DNA primase activity
CUGBS08_RS07010	COG1970	mechanosensitive ion channel activity
CUGBS08_RS07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS08_RS07030	COG0004	ammonium transporteR
CUGBS08_RS07040	COG1054	Belongs to the UPF0176 family
CUGBS08_RS07050	COG2271	Major facilitator Superfamily
CUGBS08_RS07055	COG0058	SHG alpha-glucan phosphorylase activity
CUGBS08_RS07060	COG1640	4-alpha-glucanotransferase
CUGBS08_RS07065	COG1609	Transcriptional regulator
CUGBS08_RS07075	COG1175	transmembrane transport
CUGBS08_RS07080	COG3833	ABC-type maltose transport systems, permease component
CUGBS08_RS07085	COG3104	oligopeptide transport
CUGBS08_RS07105	COG0438	transferase activity, transferring glycosyl groups
CUGBS08_RS07110	COG0653	protein targeting
CUGBS08_RS07130	COG0201	protein transport
CUGBS08_RS07135	COG1442	glycosyl transferase family 8
CUGBS08_RS07140	COG1216	Glycosyl transferase, family 2
CUGBS08_RS07140	COG1442	glycosyl transferase family 8
CUGBS08_RS07145	COG1442	glycosyl transferase family 8
CUGBS08_RS07150	COG1442	glycosyl transferase family 8
CUGBS08_RS07150	COG1216	Glycosyl transferase, family 2
CUGBS08_RS07155	COG1442	glycosyl transferase family 8
CUGBS08_RS07185	COG0765	amino acid transport
CUGBS08_RS07190	COG1126	abc transporter atp-binding protein
CUGBS08_RS07215	COG2309	aminopeptidase activity
CUGBS08_RS07225	COG0154	amidase activity
CUGBS08_RS07230	COG1187	pseudouridine synthase activity
CUGBS08_RS07235	COG0656	L-ascorbic acid biosynthetic process
CUGBS08_RS07240	COG0778	Nitroreductase
CUGBS08_RS07245	COG0346	lactoylglutathione lyase activity
CUGBS08_RS07250	COG0463	Glycosyl transferase, family 2
CUGBS08_RS07255	COG1113	amino acid transport
CUGBS08_RS07260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CUGBS08_RS07265	COG0557	exoribonuclease II activity
CUGBS08_RS07275	COG2814	Major facilitator Superfamily
CUGBS08_RS07285	COG1131	(ABC) transporter
CUGBS08_RS07290	COG0237	dephospho-CoA kinase activity
CUGBS08_RS07295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CUGBS08_RS07300	COG1396	sequence-specific DNA binding
CUGBS08_RS07340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CUGBS08_RS07345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CUGBS08_RS07365	COG1702	phosphate starvation-inducible protein PhoH
CUGBS08_RS07380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUGBS08_RS07390	COG0233	cytoplasmic translational termination
CUGBS08_RS07405	COG0444	Belongs to the ABC transporter superfamily
CUGBS08_RS07410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS08_RS07415	COG0601	transmembrane transport
CUGBS08_RS07420	COG0747	negative chemotaxis
CUGBS08_RS07425	COG0081	regulation of translation
CUGBS08_RS07430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CUGBS08_RS07440	COG1473	amidohydrolase
CUGBS08_RS07445	COG0583	DNA-binding transcription factor activity
CUGBS08_RS07455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUGBS08_RS07460	COG1674	ftsk spoiiie
CUGBS08_RS07465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUGBS08_RS07490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUGBS08_RS07520	COG0673	inositol 2-dehydrogenase activity
CUGBS08_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS08_RS07585	COG1114	Component of the transport system for branched-chain amino acids
CUGBS08_RS07590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS08_RS07590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS08_RS07605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUGBS08_RS07615	COG0708	Exodeoxyribonuclease III
CUGBS08_RS07620	COG1393	Belongs to the ArsC family
CUGBS08_RS07625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUGBS08_RS07630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUGBS08_RS07640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CUGBS08_RS07660	COG0470	DNA polymerase III
CUGBS08_RS07670	COG0517	IMP dehydrogenase activity
CUGBS08_RS07710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CUGBS08_RS07715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUGBS08_RS07725	COG0531	amino acid
CUGBS08_RS07730	COG0569	domain protein
CUGBS08_RS07745	COG1187	pseudouridine synthase activity
CUGBS08_RS07755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CUGBS08_RS07760	COG0582	viral genome integration into host DNA
CUGBS08_RS07780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUGBS08_RS07795	COG1827	regulation of RNA biosynthetic process
CUGBS08_RS07810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUGBS08_RS07815	COG1254	Belongs to the acylphosphatase family
CUGBS08_RS07820	COG0706	membrane insertase activity
CUGBS08_RS07825	COG0765	amino acid transport
CUGBS08_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS08_RS07845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUGBS08_RS07855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUGBS08_RS07875	COG1484	DNA-dependent DNA replication
CUGBS08_RS07890	COG5002	protein histidine kinase activity
CUGBS08_RS07895	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS07905	COG0501	Belongs to the peptidase M48B family
CUGBS08_RS07910	COG1704	LemA family
CUGBS08_RS07915	COG0357	Ribosomal RNA small subunit methyltransferase G
CUGBS08_RS07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUGBS08_RS07925	COG0569	domain protein
CUGBS08_RS07935	COG1122	ATPase activity
CUGBS08_RS07945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CUGBS08_RS07950	COG1114	Component of the transport system for branched-chain amino acids
CUGBS08_RS07955	COG1063	alcohol dehydrogenase
CUGBS08_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS08_RS07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CUGBS08_RS07990	COG0217	transcriptional regulatory protein
CUGBS08_RS07995	COG2376	Dihydroxyacetone kinase
CUGBS08_RS08000	COG1309	transcriptional regulator
CUGBS08_RS08005	COG2376	Dihydroxyacetone kinase
CUGBS08_RS08010	COG1461	Dihydroxyacetone kinase
CUGBS08_RS08015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CUGBS08_RS08020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS08_RS08030	COG0789	Transcriptional regulator
CUGBS08_RS08045	COG2226	methyltransferase
CUGBS08_RS08050	COG0799	negative regulation of ribosome biogenesis
CUGBS08_RS08060	COG1713	HD superfamily hydrolase involved in NAD metabolism
CUGBS08_RS08065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CUGBS08_RS08070	COG1534	Rna-binding protein
CUGBS08_RS08075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CUGBS08_RS08080	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CUGBS08_RS08105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUGBS08_RS08105	COG0574	Belongs to the PEP-utilizing enzyme family
CUGBS08_RS08115	COG0517	IMP dehydrogenase activity
CUGBS08_RS08125	COG1335	isochorismatase
CUGBS08_RS08130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUGBS08_RS08135	COG0436	Aminotransferase
CUGBS08_RS08140	COG0589	response to stress
CUGBS08_RS08145	COG0561	phosphatase activity
CUGBS08_RS08150	COG0252	asparaginase activity
CUGBS08_RS08160	COG4989	oxidoreductase activity
CUGBS08_RS08165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUGBS08_RS08170	COG3942	CHAP domain
CUGBS08_RS08170	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS08_RS08180	COG0736	holo-[acyl-carrier-protein] synthase activity
CUGBS08_RS08185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUGBS08_RS08195	COG1482	cell wall glycoprotein biosynthetic process
CUGBS08_RS08200	COG1940	carbohydrate kinase activity
CUGBS08_RS08205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS08_RS08205	COG1263	PTS System
CUGBS08_RS08205	COG2190	(PTS) system
CUGBS08_RS08210	COG1621	beta-fructofuranosidase activity
CUGBS08_RS08215	COG1609	Transcriptional regulator
CUGBS08_RS08220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUGBS08_RS08230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CUGBS08_RS08250	COG2131	deaminase
CUGBS08_RS08265	COG2814	Major facilitator Superfamily
CUGBS08_RS08290	COG0629	single-stranded DNA binding
CUGBS08_RS08295	COG0360	Binds together with S18 to 16S ribosomal RNA
CUGBS08_RS08300	COG1194	a g-specific adenine glycosylase
CUGBS08_RS08310	COG3118	belongs to the thioredoxin family
CUGBS08_RS08340	COG0681	Belongs to the peptidase S26 family
CUGBS08_RS08345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUGBS08_RS08360	COG1882	Formate acetyltransferase
CUGBS08_RS08365	COG3576	pyridoxamine 5-phosphate
CUGBS08_RS08370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUGBS08_RS08385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS08_RS08395	COG2814	Major facilitator Superfamily
CUGBS08_RS08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUGBS08_RS08415	COG0142	geranyltranstransferase activity
CUGBS08_RS08420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CUGBS08_RS08425	COG4988	ABC transporter
CUGBS08_RS08430	COG1294	oxidase, subunit
CUGBS08_RS08435	COG1271	oxidase subunit
CUGBS08_RS08440	COG1252	NADH dehydrogenase
CUGBS08_RS08475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUGBS08_RS08480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS08_RS08480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS08_RS08480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CUGBS08_RS08485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS08_RS08490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS08_RS08495	COG3711	transcriptional antiterminator
CUGBS08_RS08495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS08_RS08515	COG4221	oxidoreductase activity
CUGBS08_RS08535	COG1674	ftsk spoiiie
CUGBS08_RS08540	COG2946	Replication initiation factor
CUGBS08_RS08570	COG0791	NLP P60 protein
CUGBS08_RS08570	COG0741	lytic transglycosylase activity
CUGBS08_RS08610	COG0656	L-ascorbic acid biosynthetic process
CUGBS08_RS08615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUGBS08_RS08630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CUGBS08_RS08635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CUGBS08_RS08640	COG0789	Transcriptional regulator
CUGBS08_RS08655	COG2081	HI0933 family
CUGBS08_RS08680	COG0456	acetyltransferase
CUGBS08_RS08685	COG1214	PFAM Peptidase M22, glycoprotease
CUGBS08_RS08700	COG3942	CHAP domain
CUGBS08_RS08705	COG0174	glutamine synthetase
CUGBS08_RS08710	COG0789	Transcriptional regulator
CUGBS08_RS08725	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CUGBS08_RS08750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUGBS08_RS08775	COG1162	GTPase activity
CUGBS08_RS08800	COG0084	hydrolase, TatD family'
CUGBS08_RS08825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CUGBS08_RS08830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS08_RS08835	COG1696	Membrane protein involved in D-alanine export
CUGBS08_RS08855	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS08865	COG3314	Sporulation integral membrane protein YlbJ
CUGBS08_RS08875	COG3448	diguanylate cyclase activity
CUGBS08_RS08875	COG4175	Glycine betaine
CUGBS08_RS08880	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CUGBS08_RS08900	COG1070	Carbohydrate kinase
CUGBS08_RS08910	COG3775	system Galactitol-specific IIC component
CUGBS08_RS08915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUGBS08_RS08925	COG1609	Transcriptional regulator
CUGBS08_RS09010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUGBS08_RS09015	COG1428	Deoxynucleoside kinase
CUGBS08_RS09025	COG0542	response to heat
CUGBS08_RS09030	COG4463	regulation of RNA biosynthetic process
CUGBS08_RS09040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CUGBS08_RS09050	COG0450	alkyl hydroperoxide reductase
CUGBS08_RS09065	COG0025	NhaP-type Na H and K H
CUGBS08_RS09075	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUGBS08_RS09080	COG3590	peptidase
CUGBS08_RS09105	COG1609	Transcriptional regulator
CUGBS08_RS09130	COG2176	DNA-directed DNA polymerase activity
CUGBS08_RS09135	COG1388	LysM domain
CUGBS08_RS09135	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS08_RS09150	COG4589	Belongs to the CDS family
CUGBS08_RS09155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CUGBS08_RS09160	COG1862	Preprotein translocase
CUGBS08_RS09175	COG3493	citrate carrier protein
CUGBS08_RS09180	COG3290	protein histidine kinase activity
CUGBS08_RS09185	COG4565	transcriptional regulatory protein
CUGBS08_RS09190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUGBS08_RS09200	COG3842	ATPase activity
CUGBS08_RS09285	COG0737	Belongs to the 5'-nucleotidase family
CUGBS08_RS09295	COG1363	Peptidase, m42
CUGBS08_RS09315	COG4753	response regulator
CUGBS08_RS09315	COG2207	Transcriptional regulator
CUGBS08_RS09320	COG2972	Histidine kinase
CUGBS08_RS09325	COG3716	PTS system mannose fructose sorbose family IID component
CUGBS08_RS09330	COG3715	PTS system
CUGBS08_RS09360	COG1131	(ABC) transporter
CUGBS08_RS09370	COG2274	protein secretion by the type I secretion system
CUGBS08_RS09375	COG3290	protein histidine kinase activity
CUGBS08_RS09390	COG2190	(PTS) system
CUGBS08_RS09390	COG1263	PTS System
CUGBS08_RS09390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS08_RS09395	COG5002	protein histidine kinase activity
CUGBS08_RS09400	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS09415	COG0581	inorganic phosphate transmembrane transporter activity
CUGBS08_RS09420	COG0573	inorganic phosphate transmembrane transporter activity
CUGBS08_RS09435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUGBS08_RS09450	COG0789	Transcriptional regulator
CUGBS08_RS09460	COG0494	nUDIX hydrolase
CUGBS08_RS09475	COG0456	acetyltransferase
CUGBS08_RS09480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUGBS08_RS09505	COG0582	viral genome integration into host DNA
CUGBS08_RS09515	COG2946	Replication initiation factor
CUGBS08_RS09530	COG2378	regulation of single-species biofilm formation
CUGBS08_RS09535	COG0693	protein deglycase activity
CUGBS08_RS09610	COG1131	(ABC) transporter
CUGBS08_RS09645	COG1131	(ABC) transporter
CUGBS08_RS09655	COG1396	sequence-specific DNA binding
CUGBS08_RS09665	COG1694	Mazg nucleotide pyrophosphohydrolase
CUGBS08_RS09670	COG1611	Belongs to the LOG family
CUGBS08_RS09680	COG2897	thiosulfate sulfurtransferase activity
CUGBS08_RS09695	COG0371	Dehydrogenase
CUGBS08_RS09705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CUGBS08_RS09705	COG0646	methionine synthase
CUGBS08_RS09720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUGBS08_RS09735	COG2770	Histidine kinase
CUGBS08_RS09735	COG2205	protein histidine kinase activity
CUGBS08_RS09750	COG2814	Major facilitator Superfamily
CUGBS08_RS09755	COG4667	esterase of the alpha-beta hydrolase superfamily
CUGBS08_RS09770	COG4667	esterase of the alpha-beta hydrolase superfamily
CUGBS08_RS09795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS08_RS09800	COG0564	pseudouridine synthase activity
CUGBS08_RS09820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUGBS08_RS09825	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CUGBS08_RS09845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CUGBS08_RS09850	COG1116	anion transmembrane transporter activity
CUGBS08_RS09850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUGBS08_RS09855	COG4120	Belongs to the binding-protein-dependent transport system permease family
CUGBS08_RS09865	COG0561	phosphatase activity
CUGBS08_RS09870	COG2514	catechol 2,3-dioxygenase activity
CUGBS08_RS09880	COG0602	queuosine metabolic process
CUGBS08_RS09900	COG1328	CTP reductase activity
CUGBS08_RS09920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUGBS08_RS09930	COG1393	Belongs to the ArsC family
CUGBS08_RS09935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CUGBS08_RS09945	COG2818	Glycosylase
CUGBS08_RS09990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS08_RS09995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS08_RS10015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUGBS08_RS10070	COG0582	viral genome integration into host DNA
CUGBS08_RS10145	COG0745	RESPONSE REGULATOR receiver
CUGBS08_RS10150	COG5002	protein histidine kinase activity
CUGBS08_RS10155	COG1288	antiporter activity
CUGBS08_RS10165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CUGBS08_RS10170	COG3852	Histidine kinase
CUGBS08_RS10175	COG0784	Response regulator, receiver
CUGBS08_RS10180	COG0517	IMP dehydrogenase activity
CUGBS08_RS10180	COG1125	glycine betaine transport
CUGBS08_RS10185	COG1174	glycine betaine transport
CUGBS08_RS10190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CUGBS08_RS10190	COG0392	lysyltransferase activity
CUGBS08_RS10200	COG3759	membrane
CUGBS08_RS10300	COG2314	TM2 domain
CUGBS08_RS10320	COG0582	viral genome integration into host DNA
CUGBS08_RS10335	COG0305	Participates in initiation and elongation during chromosome replication
CUGBS08_RS10355	COG2095	MarC family integral membrane protein
CUGBS08_RS10360	COG0482	sulfurtransferase activity
CUGBS08_RS10365	COG1760	l-serine dehydratase
CUGBS08_RS10370	COG1760	l-serine dehydratase
CUGBS08_RS10400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUGBS08_RS10405	COG0612	Peptidase, M16
CUGBS08_RS10410	COG0612	Peptidase, M16
CUGBS08_RS10415	COG2501	S4 domain
CUGBS08_RS10435	COG0516	GMP reductase activity
CUGBS08_RS10435	COG0517	IMP dehydrogenase activity
CUGBS08_RS10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUGBS08_RS10460	COG0454	-acetyltransferase
CUGBS08_RS10475	COG0549	Belongs to the carbamate kinase family
CUGBS08_RS10490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS08_RS10495	COG0488	(ABC) transporter
CUGBS08_RS10500	COG4485	Bacterial membrane protein, YfhO
CUGBS08_RS10520	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CUGBS08_RS10525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUGBS08_RS10530	COG1475	DNA binding
CUGBS08_RS10540	COG0592	DNA-directed DNA polymerase activity
CUGBS08_RS10545	COG1597	lipid kinase activity
CUGBS08_RS10555	COG0012	GTP binding
CUGBS08_RS10565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CUGBS08_RS10570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CUGBS08_RS10600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins