locus-tag	class	description
CUGBS98_RS00105	COG0436	Aminotransferase
CUGBS98_RS00125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS98_RS00135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUGBS98_RS00150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUGBS98_RS00185	COG1175	transmembrane transport
CUGBS98_RS00190	COG0395	ABC-type sugar transport system, permease component
CUGBS98_RS00205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUGBS98_RS00215	COG3458	cephalosporin-C deacetylase activity
CUGBS98_RS00230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CUGBS98_RS00245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUGBS98_RS00260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUGBS98_RS00270	COG2755	lipolytic protein G-D-S-L family
CUGBS98_RS00270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CUGBS98_RS00275	COG1454	alcohol dehydrogenase
CUGBS98_RS00275	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS98_RS00280	COG1064	alcohol dehydrogenase
CUGBS98_RS00290	COG0534	Mate efflux family protein
CUGBS98_RS00400	COG0201	protein transport
CUGBS98_RS00415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CUGBS98_RS00425	COG0202	RNA polymerase activity
CUGBS98_RS00560	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS98_RS00575	COG0443	Heat shock 70 kDa protein
CUGBS98_RS00585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUGBS98_RS00595	COG0351	phosphomethylpyrimidine kinase
CUGBS98_RS00600	COG4720	Psort location CytoplasmicMembrane, score
CUGBS98_RS00610	COG0668	transmembrane transport
CUGBS98_RS00640	COG0756	dUTP diphosphatase activity
CUGBS98_RS00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUGBS98_RS00670	COG1879	ABC-type sugar transport system periplasmic component
CUGBS98_RS00675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUGBS98_RS00690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUGBS98_RS00695	COG1609	Transcriptional regulator
CUGBS98_RS00700	COG0577	efflux transmembrane transporter activity
CUGBS98_RS00705	COG1136	(ABC) transporter
CUGBS98_RS00710	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS00715	COG5002	protein histidine kinase activity
CUGBS98_RS00730	COG0191	fructose-bisphosphate aldolase activity
CUGBS98_RS00750	COG1461	Dihydroxyacetone kinase
CUGBS98_RS00790	COG1126	abc transporter atp-binding protein
CUGBS98_RS00795	COG0765	amino acid transport
CUGBS98_RS00815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUGBS98_RS00825	COG0719	Fe-S assembly protein
CUGBS98_RS00830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUGBS98_RS00840	COG0719	Fe-S assembly protein
CUGBS98_RS00845	COG1686	Belongs to the peptidase S11 family
CUGBS98_RS00850	COG1686	Belongs to the peptidase S11 family
CUGBS98_RS00855	COG4166	transmembrane transport
CUGBS98_RS00860	COG0601	transmembrane transport
CUGBS98_RS00865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS98_RS00870	COG0444	Belongs to the ABC transporter superfamily
CUGBS98_RS00875	COG4608	Belongs to the ABC transporter superfamily
CUGBS98_RS00915	COG1121	(ABC) transporter
CUGBS98_RS00920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUGBS98_RS00935	COG4499	WXG100 protein secretion system (Wss), protein YukC
CUGBS98_RS00935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS98_RS00955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUGBS98_RS00960	COG1459	type II secretion system
CUGBS98_RS01015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUGBS98_RS01020	COG1363	Peptidase, m42
CUGBS98_RS01035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUGBS98_RS01040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS98_RS01055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUGBS98_RS01075	COG1346	cytolysis
CUGBS98_RS01085	COG0601	transmembrane transport
CUGBS98_RS01090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS98_RS01095	COG1122	ATPase activity
CUGBS98_RS01105	COG1263	PTS System
CUGBS98_RS01105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS98_RS01110	COG0366	Alpha amylase catalytic
CUGBS98_RS01115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS98_RS01130	COG3959	Transketolase, thiamine diphosphate binding domain
CUGBS98_RS01135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUGBS98_RS01140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUGBS98_RS01160	COG1045	serine acetyltransferase
CUGBS98_RS01175	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CUGBS98_RS01195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CUGBS98_RS01205	COG4974	Belongs to the 'phage' integrase family
CUGBS98_RS01310	COG1396	sequence-specific DNA binding
CUGBS98_RS01315	COG2814	Major facilitator Superfamily
CUGBS98_RS01325	COG1732	Glycine betaine
CUGBS98_RS01460	COG0519	Catalyzes the synthesis of GMP from XMP
CUGBS98_RS01505	COG1695	Transcriptional regulator
CUGBS98_RS01520	COG1755	Isoprenylcysteine carboxyl methyltransferase
CUGBS98_RS01560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS98_RS01565	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUGBS98_RS01585	COG1131	(ABC) transporter
CUGBS98_RS01595	COG1263	PTS System
CUGBS98_RS01595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS98_RS01595	COG2190	(PTS) system
CUGBS98_RS01600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CUGBS98_RS01620	COG0768	penicillin binding
CUGBS98_RS01630	COG0513	Belongs to the DEAD box helicase family
CUGBS98_RS01645	COG1126	abc transporter atp-binding protein
CUGBS98_RS01655	COG0492	ferredoxin-NADP+ reductase activity
CUGBS98_RS01660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CUGBS98_RS01670	COG3579	cysteine-type endopeptidase activity
CUGBS98_RS01675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS98_RS01700	COG0116	Belongs to the methyltransferase superfamily
CUGBS98_RS01710	COG1854	S-ribosylhomocysteine lyase activity
CUGBS98_RS01715	COG4372	Transposase
CUGBS98_RS01715	COG1418	mRNA catabolic process
CUGBS98_RS01720	COG1131	(ABC) transporter
CUGBS98_RS01730	COG4585	Histidine kinase
CUGBS98_RS01735	COG2197	response regulator
CUGBS98_RS01745	COG0194	GDP metabolic process
CUGBS98_RS01755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUGBS98_RS01760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CUGBS98_RS01765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUGBS98_RS01765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUGBS98_RS01775	COG2815	serine threonine protein kinase
CUGBS98_RS01775	COG0515	serine threonine protein kinase
CUGBS98_RS01785	COG4585	Histidine kinase
CUGBS98_RS01790	COG2197	response regulator
CUGBS98_RS01800	COG1098	S1 RNA binding domain
CUGBS98_RS01805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUGBS98_RS01810	COG1349	DNA-binding transcription factor activity
CUGBS98_RS01820	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUGBS98_RS01830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUGBS98_RS01835	COG1882	Formate acetyltransferase
CUGBS98_RS01855	COG1739	Uncharacterized protein family UPF0029
CUGBS98_RS01860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CUGBS98_RS01865	COG1040	competence protein
CUGBS98_RS01900	COG0527	aspartate kinase activity
CUGBS98_RS01905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUGBS98_RS01910	COG1024	Enoyl-CoA hydratase
CUGBS98_RS01920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUGBS98_RS01930	COG2070	2-Nitropropane dioxygenase
CUGBS98_RS01935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUGBS98_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS98_RS01945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUGBS98_RS01960	COG0439	Biotin carboxylase
CUGBS98_RS01980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CUGBS98_RS01995	COG3716	PTS system mannose fructose sorbose family IID component
CUGBS98_RS02000	COG3715	PTS system
CUGBS98_RS02010	COG0561	phosphatase activity
CUGBS98_RS02025	COG2252	PERMEase
CUGBS98_RS02030	COG0802	atpase or kinase
CUGBS98_RS02040	COG1316	TRANSCRIPTIONal
CUGBS98_RS02050	COG0537	adenosine 5'-monophosphoramidase activity
CUGBS98_RS02065	COG1131	(ABC) transporter
CUGBS98_RS02070	COG4473	ABC transporter
CUGBS98_RS02080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUGBS98_RS02095	COG0195	Participates in both transcription termination and antitermination
CUGBS98_RS02100	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CUGBS98_RS02110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CUGBS98_RS02115	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CUGBS98_RS02140	COG2860	membrane
CUGBS98_RS02150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUGBS98_RS02150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUGBS98_RS02155	COG1832	CoA-binding protein
CUGBS98_RS02175	COG5002	protein histidine kinase activity
CUGBS98_RS02195	COG1268	BioY protein
CUGBS98_RS02200	COG1234	tRNA 3'-trailer cleavage
CUGBS98_RS02215	COG0166	Belongs to the GPI family
CUGBS98_RS02220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUGBS98_RS02225	COG0457	Tetratricopeptide repeat
CUGBS98_RS02225	COG0705	Rhomboid family
CUGBS98_RS02230	COG1744	ABC transporter substrate-binding protein PnrA-like
CUGBS98_RS02235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUGBS98_RS02250	COG0706	membrane insertase activity
CUGBS98_RS02310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUGBS98_RS02320	COG2153	protein acetylation
CUGBS98_RS02330	COG1442	glycosyl transferase family 8
CUGBS98_RS02330	COG1216	Glycosyl transferase, family 2
CUGBS98_RS02365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUGBS98_RS02375	COG0789	Transcriptional regulator
CUGBS98_RS02385	COG0656	L-ascorbic acid biosynthetic process
CUGBS98_RS02430	COG2226	methyltransferase
CUGBS98_RS02440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS98_RS02445	COG3414	Phosphotransferase system galactitol-specific IIB component
CUGBS98_RS02450	COG3775	system Galactitol-specific IIC component
CUGBS98_RS02455	COG0235	Class ii aldolase
CUGBS98_RS02465	COG3775	system Galactitol-specific IIC component
CUGBS98_RS02470	COG3414	Phosphotransferase system galactitol-specific IIB component
CUGBS98_RS02475	COG2207	Transcriptional regulator
CUGBS98_RS02495	COG1175	transmembrane transport
CUGBS98_RS02510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CUGBS98_RS02520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUGBS98_RS02525	COG2017	converts alpha-aldose to the beta-anomer
CUGBS98_RS02585	COG1518	maintenance of DNA repeat elements
CUGBS98_RS02590	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CUGBS98_RS02595	COG0673	inositol 2-dehydrogenase activity
CUGBS98_RS02605	COG2315	Protein conserved in bacteria
CUGBS98_RS02620	COG0742	ribosomal rna small subunit methyltransferase
CUGBS98_RS02635	COG3480	Lon protease (S16) C-terminal proteolytic domain
CUGBS98_RS02640	COG0737	Belongs to the 5'-nucleotidase family
CUGBS98_RS02645	COG4470	Protein conserved in bacteria
CUGBS98_RS02660	COG1132	(ABC) transporter
CUGBS98_RS02665	COG1132	(ABC) transporter
CUGBS98_RS02670	COG0512	Glutamine amidotransferase of anthranilate synthase
CUGBS98_RS02680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CUGBS98_RS02700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUGBS98_RS02715	COG1940	carbohydrate kinase activity
CUGBS98_RS02720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUGBS98_RS02725	COG1217	gtp-binding protein TYPA
CUGBS98_RS02735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CUGBS98_RS02760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CUGBS98_RS02770	COG0762	integral membrane protein
CUGBS98_RS02775	COG2302	S4 RNA-binding domain
CUGBS98_RS02780	COG3599	regulation of cell shape
CUGBS98_RS02795	COG0494	nUDIX hydrolase
CUGBS98_RS02800	COG0542	response to heat
CUGBS98_RS02805	COG4703	Protein of unknown function (DUF1797)
CUGBS98_RS02810	COG0765	amino acid transport
CUGBS98_RS02815	COG1126	abc transporter atp-binding protein
CUGBS98_RS02820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUGBS98_RS02830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUGBS98_RS02835	COG1570	exodeoxyribonuclease VII activity
CUGBS98_RS02840	COG1722	exodeoxyribonuclease VII activity
CUGBS98_RS02850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CUGBS98_RS02855	COG1438	arginine binding
CUGBS98_RS02860	COG0497	DNA recombination
CUGBS98_RS02865	COG1307	EDD domain protein, DegV family
CUGBS98_RS02870	COG2755	lipolytic protein G-D-S-L family
CUGBS98_RS02915	COG1078	dGTPase activity
CUGBS98_RS02940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUGBS98_RS02950	COG2884	Cell division ATP-binding protein ftsE
CUGBS98_RS02955	COG2177	Part of the ABC transporter FtsEX involved in
CUGBS98_RS02975	COG1199	ATP-dependent helicase activity
CUGBS98_RS02975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUGBS98_RS02980	COG0436	Aminotransferase
CUGBS98_RS02985	COG0017	Asparaginyl-tRNA synthetase
CUGBS98_RS03005	COG1660	Displays ATPase and GTPase activities
CUGBS98_RS03030	COG0254	rRNA binding
CUGBS98_RS03035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CUGBS98_RS03040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CUGBS98_RS03045	COG0716	FMN binding
CUGBS98_RS03050	COG1605	Chorismate mutase
CUGBS98_RS03050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CUGBS98_RS03055	COG0038	chloride channel
CUGBS98_RS03060	COG0335	large ribosomal subunit rRNA binding
CUGBS98_RS03095	COG1136	(ABC) transporter
CUGBS98_RS03110	COG5002	protein histidine kinase activity
CUGBS98_RS03125	COG0772	Belongs to the SEDS family
CUGBS98_RS03145	COG0560	Phosphoserine phosphatase
CUGBS98_RS03160	COG0148	phosphopyruvate hydratase activity
CUGBS98_RS03180	COG1316	TRANSCRIPTIONal
CUGBS98_RS03195	COG3700	Belongs to the class B bacterial acid phosphatase family
CUGBS98_RS03295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUGBS98_RS03300	COG4555	ABC transporter
CUGBS98_RS03325	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS98_RS03330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS98_RS03335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUGBS98_RS03355	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CUGBS98_RS03360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUGBS98_RS03380	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUGBS98_RS03380	COG3064	Membrane
CUGBS98_RS03395	COG3590	peptidase
CUGBS98_RS03400	COG3590	peptidase
CUGBS98_RS03445	COG1136	(ABC) transporter
CUGBS98_RS03460	COG0586	Pfam SNARE associated Golgi protein
CUGBS98_RS03465	COG4619	ABC transporter
CUGBS98_RS03470	COG0390	transport system, permease component
CUGBS98_RS03480	COG0583	DNA-binding transcription factor activity
CUGBS98_RS03495	COG2211	Major facilitator Superfamily
CUGBS98_RS03505	COG3250	beta-galactosidase activity
CUGBS98_RS03510	COG2186	Transcriptional regulator
CUGBS98_RS03515	COG0800	Aldolase
CUGBS98_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS98_RS03550	COG1609	Transcriptional regulator
CUGBS98_RS03565	COG0438	transferase activity, transferring glycosyl groups
CUGBS98_RS03590	COG0765	amino acid transport
CUGBS98_RS03595	COG0765	amino acid transport
CUGBS98_RS03600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS98_RS03605	COG1126	abc transporter atp-binding protein
CUGBS98_RS03610	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS03615	COG5002	protein histidine kinase activity
CUGBS98_RS03620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CUGBS98_RS03625	COG2832	Protein of unknown function (DUF454)
CUGBS98_RS03635	COG1196	nuclear chromosome segregation
CUGBS98_RS03640	COG0561	phosphatase activity
CUGBS98_RS03645	COG0561	phosphatase activity
CUGBS98_RS03650	COG0552	protein localization to endoplasmic reticulum
CUGBS98_RS03655	COG3689	TIGRFAM TIGR03943 family protein
CUGBS98_RS03660	COG0701	Predicted permease
CUGBS98_RS03675	COG2183	response to ionizing radiation
CUGBS98_RS03680	COG3091	SprT-like family
CUGBS98_RS03685	COG1983	PspC domain protein
CUGBS98_RS03720	COG0826	peptidase U32
CUGBS98_RS03725	COG4443	Transcriptional Coactivator p15 (PC4)
CUGBS98_RS03735	COG1914	H( )-stimulated, divalent metal cation uptake system
CUGBS98_RS03750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUGBS98_RS03750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUGBS98_RS03775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUGBS98_RS03800	COG1164	Oligoendopeptidase f
CUGBS98_RS03810	COG0772	Belongs to the SEDS family
CUGBS98_RS03830	COG0768	penicillin binding
CUGBS98_RS03845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUGBS98_RS03850	COG2223	nitrite transmembrane transporter activity
CUGBS98_RS03880	COG2011	ABC-type metal ion transport system permease component
CUGBS98_RS03885	COG1464	Belongs to the NlpA lipoprotein family
CUGBS98_RS03890	COG0513	Belongs to the DEAD box helicase family
CUGBS98_RS03900	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CUGBS98_RS03905	COG0204	Acyl-transferase
CUGBS98_RS03910	COG1555	photosystem II stabilization
CUGBS98_RS03910	COG1596	polysaccharide export
CUGBS98_RS03915	COG2333	competence protein COMEC
CUGBS98_RS03915	COG0658	competence protein
CUGBS98_RS03920	COG0561	phosphatase activity
CUGBS98_RS03925	COG1609	Transcriptional regulator
CUGBS98_RS03930	COG0657	acetylesterase activity
CUGBS98_RS03935	COG2226	methyltransferase
CUGBS98_RS03945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUGBS98_RS03950	COG3711	transcriptional antiterminator
CUGBS98_RS03955	COG2190	(PTS) system
CUGBS98_RS03955	COG1263	PTS System
CUGBS98_RS03955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS98_RS03965	COG3835	regulator
CUGBS98_RS03970	COG1929	Belongs to the glycerate kinase type-1 family
CUGBS98_RS03975	COG2610	gluconate transmembrane transporter activity
CUGBS98_RS03985	COG1846	Transcriptional regulator
CUGBS98_RS04000	COG0363	glucosamine-6-phosphate deaminase activity
CUGBS98_RS04005	COG0435	Glutathione S-transferase
CUGBS98_RS04010	COG1187	pseudouridine synthase activity
CUGBS98_RS04030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CUGBS98_RS04035	COG4122	O-methyltransferase activity
CUGBS98_RS04045	COG4894	glucomannan catabolic process
CUGBS98_RS04060	COG1442	glycosyl transferase family 8
CUGBS98_RS04075	COG1476	TRANSCRIPTIONal
CUGBS98_RS04090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUGBS98_RS04095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUGBS98_RS04100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUGBS98_RS04115	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS98_RS04120	COG0726	polysaccharide deacetylase
CUGBS98_RS04135	COG1956	GAF domain-containing protein
CUGBS98_RS04140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUGBS98_RS04150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CUGBS98_RS04150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CUGBS98_RS04180	COG4721	ABC-type cobalt transport system, permease component
CUGBS98_RS04185	COG1122	ATPase activity
CUGBS98_RS04195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUGBS98_RS04225	COG4109	DRTGG domain
CUGBS98_RS04230	COG0024	Methionine aminopeptidase
CUGBS98_RS04240	COG2246	polysaccharide biosynthetic process
CUGBS98_RS04245	COG4708	membrane
CUGBS98_RS04255	COG1597	lipid kinase activity
CUGBS98_RS04260	COG1523	belongs to the glycosyl hydrolase 13 family
CUGBS98_RS04275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CUGBS98_RS04355	COG0072	phenylalanine-tRNA ligase activity
CUGBS98_RS04355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS98_RS04360	COG2321	neutral zinc metallopeptidase
CUGBS98_RS04385	COG0488	(ABC) transporter
CUGBS98_RS04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CUGBS98_RS04395	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUGBS98_RS04395	COG0022	dehydrogenase e1 component
CUGBS98_RS04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUGBS98_RS04410	COG0095	Lipoate-protein ligase
CUGBS98_RS04415	COG3442	glutamine amidotransferase
CUGBS98_RS04420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUGBS98_RS04425	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CUGBS98_RS04450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUGBS98_RS04460	COG0647	UMP catabolic process
CUGBS98_RS04470	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CUGBS98_RS04475	COG1518	maintenance of DNA repeat elements
CUGBS98_RS04480	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CUGBS98_RS04500	COG0481	GTPase activity
CUGBS98_RS04510	COG1418	mRNA catabolic process
CUGBS98_RS04515	COG0456	acetyltransferase
CUGBS98_RS04525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUGBS98_RS04555	COG1131	(ABC) transporter
CUGBS98_RS04560	COG1725	Transcriptional regulator
CUGBS98_RS04570	COG0205	6-phosphofructokinase activity
CUGBS98_RS04575	COG0469	pyruvate kinase activity
CUGBS98_RS04585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CUGBS98_RS04590	COG2824	Alkylphosphonate utilization operon protein PhnA
CUGBS98_RS04595	COG0765	amino acid transport
CUGBS98_RS04600	COG1126	abc transporter atp-binding protein
CUGBS98_RS04615	COG1072	(Pantothenic acid kinase))
CUGBS98_RS04620	COG2813	Specifically methylates the guanine in position
CUGBS98_RS04630	COG1744	ABC transporter substrate-binding protein PnrA-like
CUGBS98_RS04635	COG3845	ABC transporter
CUGBS98_RS04640	COG4603	Belongs to the binding-protein-dependent transport system permease family
CUGBS98_RS04645	COG1079	Belongs to the binding-protein-dependent transport system permease family
CUGBS98_RS04665	COG3764	Sortase (surface protein transpeptidase)
CUGBS98_RS04670	COG0346	lactoylglutathione lyase activity
CUGBS98_RS04700	COG2188	Transcriptional regulator
CUGBS98_RS04715	COG1464	Belongs to the NlpA lipoprotein family
CUGBS98_RS04730	COG1136	(ABC) transporter
CUGBS98_RS04740	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS04745	COG5002	protein histidine kinase activity
CUGBS98_RS04750	COG4974	Belongs to the 'phage' integrase family
CUGBS98_RS04755	COG4166	transmembrane transport
CUGBS98_RS04770	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUGBS98_RS04775	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CUGBS98_RS04780	COG5002	protein histidine kinase activity
CUGBS98_RS04785	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS04795	COG0704	Plays a role in the regulation of phosphate uptake
CUGBS98_RS04800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUGBS98_RS04805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUGBS98_RS04810	COG0581	inorganic phosphate transmembrane transporter activity
CUGBS98_RS04815	COG0573	inorganic phosphate transmembrane transporter activity
CUGBS98_RS04825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUGBS98_RS04825	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CUGBS98_RS04830	COG0483	inositol monophosphate 1-phosphatase activity
CUGBS98_RS04845	COG0196	riboflavin kinase activity
CUGBS98_RS04850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUGBS98_RS04880	COG1136	(ABC) transporter
CUGBS98_RS04885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CUGBS98_RS04890	COG0758	DNA mediated transformation
CUGBS98_RS04895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CUGBS98_RS04900	COG4604	ABC transporter, ATP-binding protein
CUGBS98_RS04905	COG4605	iron ion homeostasis
CUGBS98_RS04910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS98_RS04915	COG0110	maltose O-acetyltransferase activity
CUGBS98_RS04925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CUGBS98_RS04930	COG1376	ErfK ybiS ycfS ynhG family protein
CUGBS98_RS04935	COG1966	Carbon starvation protein
CUGBS98_RS04940	COG3279	Response regulator of the LytR AlgR family
CUGBS98_RS04945	COG3275	phosphorelay sensor kinase activity
CUGBS98_RS05050	COG0505	Belongs to the CarA family
CUGBS98_RS05060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CUGBS98_RS05080	COG0488	(ABC) transporter
CUGBS98_RS05100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUGBS98_RS05140	COG0095	Lipoate-protein ligase
CUGBS98_RS05150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUGBS98_RS05155	COG4684	Psort location CytoplasmicMembrane, score
CUGBS98_RS05160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUGBS98_RS05170	COG1132	(ABC) transporter
CUGBS98_RS05200	COG2890	protein-(glutamine-N5) methyltransferase activity
CUGBS98_RS05215	COG1942	4-Oxalocrotonate Tautomerase
CUGBS98_RS05230	COG3976	FMN-binding domain protein
CUGBS98_RS05230	COG1053	succinate dehydrogenase
CUGBS98_RS05230	COG0431	NADPH-dependent FMN reductase
CUGBS98_RS05240	COG2233	PERMEase
CUGBS98_RS05255	COG0477	Major facilitator Superfamily
CUGBS98_RS05270	COG4221	oxidoreductase activity
CUGBS98_RS05275	COG0280	phosphate acetyltransferase
CUGBS98_RS05280	COG0564	pseudouridine synthase activity
CUGBS98_RS05285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUGBS98_RS05290	COG2357	RelA SpoT domain protein
CUGBS98_RS05305	COG1104	cysteine desulfurase activity
CUGBS98_RS05315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CUGBS98_RS05320	COG2003	Belongs to the UPF0758 family
CUGBS98_RS05325	COG0628	permease
CUGBS98_RS05330	COG2723	6-phospho-beta-galactosidase activity
CUGBS98_RS05340	COG0561	phosphatase activity
CUGBS98_RS05350	COG0038	chloride channel
CUGBS98_RS05360	COG1177	transmembrane transport
CUGBS98_RS05365	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUGBS98_RS05375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CUGBS98_RS05380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUGBS98_RS05400	COG0285	dihydrofolate synthase activity
CUGBS98_RS05405	COG2962	Rard protein
CUGBS98_RS05420	COG0726	polysaccharide deacetylase
CUGBS98_RS05425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUGBS98_RS05445	COG1012	belongs to the aldehyde dehydrogenase family
CUGBS98_RS05525	COG2261	transglycosylase associated protein
CUGBS98_RS05550	COG1115	amino acid carrier protein
CUGBS98_RS05555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CUGBS98_RS05565	COG1346	cytolysis
CUGBS98_RS05580	COG0539	negative regulation of cytoplasmic translation
CUGBS98_RS05600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUGBS98_RS05610	COG0187	DNA topoisomerase II activity
CUGBS98_RS05615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CUGBS98_RS05635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CUGBS98_RS05645	COG1083	cytidylyl-transferase
CUGBS98_RS05645	COG2755	lipolytic protein G-D-S-L family
CUGBS98_RS05660	COG2089	acid synthase
CUGBS98_RS05675	COG1216	Glycosyl transferase, family 2
CUGBS98_RS05675	COG1442	glycosyl transferase family 8
CUGBS98_RS05680	COG1442	glycosyl transferase family 8
CUGBS98_RS05680	COG1216	Glycosyl transferase, family 2
CUGBS98_RS05695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUGBS98_RS05720	COG1316	TRANSCRIPTIONal
CUGBS98_RS05745	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CUGBS98_RS05760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CUGBS98_RS05780	COG3842	ATPase activity
CUGBS98_RS05795	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CUGBS98_RS05800	COG3527	Alpha-acetolactate decarboxylase
CUGBS98_RS05805	COG0028	Belongs to the TPP enzyme family
CUGBS98_RS05810	COG0457	Tetratricopeptide repeat
CUGBS98_RS05815	COG0628	permease
CUGBS98_RS05825	COG1051	belongs to the nudix hydrolase family
CUGBS98_RS05830	COG5492	domain, Protein
CUGBS98_RS05835	COG1088	dTDP-glucose 4,6-dehydratase activity
CUGBS98_RS05845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CUGBS98_RS05850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUGBS98_RS05860	COG2384	SAM-dependent methyltransferase
CUGBS98_RS05880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CUGBS98_RS05880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUGBS98_RS05885	COG0300	oxidoreductase activity
CUGBS98_RS05900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUGBS98_RS05930	COG1573	uracil-dna glycosylase
CUGBS98_RS05935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUGBS98_RS05945	COG0584	glycerophosphoryl diester phosphodiesterase
CUGBS98_RS05950	COG0322	excinuclease ABC activity
CUGBS98_RS05960	COG0534	Mate efflux family protein
CUGBS98_RS05995	COG2801	Transposase and inactivated derivatives
CUGBS98_RS06005	COG0803	Belongs to the bacterial solute-binding protein 9 family
CUGBS98_RS06030	COG2176	DNA-directed DNA polymerase activity
CUGBS98_RS06040	COG4974	Belongs to the 'phage' integrase family
CUGBS98_RS06070	COG1674	ftsk spoiiie
CUGBS98_RS06110	COG2040	homocysteine
CUGBS98_RS06115	COG0833	amino acid
CUGBS98_RS06150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CUGBS98_RS06160	COG3425	synthase
CUGBS98_RS06175	COG1272	protein, Hemolysin III
CUGBS98_RS06220	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS06225	COG2357	RelA SpoT domain protein
CUGBS98_RS06230	COG1132	(ABC) transporter
CUGBS98_RS06245	COG0737	Belongs to the 5'-nucleotidase family
CUGBS98_RS06250	COG0242	peptide deformylase activity
CUGBS98_RS06255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUGBS98_RS06265	COG1132	(ABC) transporter
CUGBS98_RS06280	COG0488	(ABC) transporter
CUGBS98_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS98_RS06310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS98_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS98_RS06315	COG1105	Belongs to the carbohydrate kinase PfkB family
CUGBS98_RS06320	COG1349	DNA-binding transcription factor activity
CUGBS98_RS06375	COG1837	Belongs to the UPF0109 family
CUGBS98_RS06380	COG0228	four-way junction DNA binding
CUGBS98_RS06385	COG0577	efflux transmembrane transporter activity
CUGBS98_RS06390	COG1136	(ABC) transporter
CUGBS98_RS06395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUGBS98_RS06405	COG0505	Belongs to the CarA family
CUGBS98_RS06415	COG0564	pseudouridine synthase activity
CUGBS98_RS06425	COG0583	DNA-binding transcription factor activity
CUGBS98_RS06430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CUGBS98_RS06450	COG0301	tRNA thio-modification
CUGBS98_RS06455	COG1104	cysteine desulfurase activity
CUGBS98_RS06465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUGBS98_RS06470	COG3679	Belongs to the UPF0342 family
CUGBS98_RS06475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CUGBS98_RS06490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUGBS98_RS06495	COG1368	sulfuric ester hydrolase activity
CUGBS98_RS06500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CUGBS98_RS06510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CUGBS98_RS06515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CUGBS98_RS06540	COG2244	polysaccharide biosynthetic process
CUGBS98_RS06545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUGBS98_RS06550	COG1120	ATPase activity
CUGBS98_RS06555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CUGBS98_RS06560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS98_RS06565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUGBS98_RS06580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUGBS98_RS06585	COG1253	flavin adenine dinucleotide binding
CUGBS98_RS06590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CUGBS98_RS06595	COG1242	4 iron, 4 sulfur cluster binding
CUGBS98_RS06600	COG0671	phosphoesterase, PA-phosphatase related
CUGBS98_RS06605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CUGBS98_RS06640	COG0297	glycogen (starch) synthase activity
CUGBS98_RS06680	COG3475	LICD family
CUGBS98_RS06695	COG0463	Glycosyl transferase, family 2
CUGBS98_RS06700	COG1215	transferase activity, transferring glycosyl groups
CUGBS98_RS06710	COG1091	dTDP-4-dehydrorhamnose reductase activity
CUGBS98_RS06715	COG2151	metal-sulfur cluster biosynthetic enzyme
CUGBS98_RS06720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CUGBS98_RS06725	COG0358	DNA primase activity
CUGBS98_RS06730	COG1970	mechanosensitive ion channel activity
CUGBS98_RS06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS98_RS06750	COG0004	ammonium transporteR
CUGBS98_RS06760	COG1054	Belongs to the UPF0176 family
CUGBS98_RS06770	COG2271	Major facilitator Superfamily
CUGBS98_RS06775	COG0058	SHG alpha-glucan phosphorylase activity
CUGBS98_RS06780	COG1640	4-alpha-glucanotransferase
CUGBS98_RS06785	COG1609	Transcriptional regulator
CUGBS98_RS06795	COG1175	transmembrane transport
CUGBS98_RS06800	COG3833	ABC-type maltose transport systems, permease component
CUGBS98_RS06805	COG3104	oligopeptide transport
CUGBS98_RS06825	COG0438	transferase activity, transferring glycosyl groups
CUGBS98_RS06830	COG0653	protein targeting
CUGBS98_RS06850	COG0201	protein transport
CUGBS98_RS06855	COG1442	glycosyl transferase family 8
CUGBS98_RS06860	COG1442	glycosyl transferase family 8
CUGBS98_RS06860	COG1216	Glycosyl transferase, family 2
CUGBS98_RS06865	COG1442	glycosyl transferase family 8
CUGBS98_RS06870	COG1442	glycosyl transferase family 8
CUGBS98_RS06870	COG1216	Glycosyl transferase, family 2
CUGBS98_RS06875	COG1442	glycosyl transferase family 8
CUGBS98_RS06905	COG0765	amino acid transport
CUGBS98_RS06910	COG1126	abc transporter atp-binding protein
CUGBS98_RS06935	COG2309	aminopeptidase activity
CUGBS98_RS06945	COG0154	amidase activity
CUGBS98_RS06950	COG1187	pseudouridine synthase activity
CUGBS98_RS06955	COG0656	L-ascorbic acid biosynthetic process
CUGBS98_RS06960	COG0778	Nitroreductase
CUGBS98_RS06965	COG0346	lactoylglutathione lyase activity
CUGBS98_RS06970	COG0463	Glycosyl transferase, family 2
CUGBS98_RS06975	COG1113	amino acid transport
CUGBS98_RS06980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CUGBS98_RS06985	COG0557	exoribonuclease II activity
CUGBS98_RS06995	COG2814	Major facilitator Superfamily
CUGBS98_RS07005	COG1131	(ABC) transporter
CUGBS98_RS07010	COG0237	dephospho-CoA kinase activity
CUGBS98_RS07015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CUGBS98_RS07020	COG1396	sequence-specific DNA binding
CUGBS98_RS07055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CUGBS98_RS07060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CUGBS98_RS07080	COG1702	phosphate starvation-inducible protein PhoH
CUGBS98_RS07095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUGBS98_RS07105	COG0233	cytoplasmic translational termination
CUGBS98_RS07120	COG0444	Belongs to the ABC transporter superfamily
CUGBS98_RS07125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUGBS98_RS07130	COG0601	transmembrane transport
CUGBS98_RS07135	COG0747	negative chemotaxis
CUGBS98_RS07140	COG0081	regulation of translation
CUGBS98_RS07145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CUGBS98_RS07155	COG1473	amidohydrolase
CUGBS98_RS07160	COG0583	DNA-binding transcription factor activity
CUGBS98_RS07170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUGBS98_RS07175	COG1674	ftsk spoiiie
CUGBS98_RS07180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUGBS98_RS07205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUGBS98_RS07235	COG0673	inositol 2-dehydrogenase activity
CUGBS98_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
CUGBS98_RS07300	COG1114	Component of the transport system for branched-chain amino acids
CUGBS98_RS07305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS98_RS07305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUGBS98_RS07320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUGBS98_RS07330	COG0708	Exodeoxyribonuclease III
CUGBS98_RS07335	COG1393	Belongs to the ArsC family
CUGBS98_RS07340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUGBS98_RS07345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUGBS98_RS07355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CUGBS98_RS07375	COG0470	DNA polymerase III
CUGBS98_RS07385	COG0517	IMP dehydrogenase activity
CUGBS98_RS07425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CUGBS98_RS07430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUGBS98_RS07440	COG0531	amino acid
CUGBS98_RS07445	COG0569	domain protein
CUGBS98_RS07460	COG1187	pseudouridine synthase activity
CUGBS98_RS07470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CUGBS98_RS07475	COG0582	viral genome integration into host DNA
CUGBS98_RS07495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUGBS98_RS07510	COG1827	regulation of RNA biosynthetic process
CUGBS98_RS07525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUGBS98_RS07530	COG1254	Belongs to the acylphosphatase family
CUGBS98_RS07535	COG0706	membrane insertase activity
CUGBS98_RS07540	COG0765	amino acid transport
CUGBS98_RS07545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS98_RS07560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUGBS98_RS07570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUGBS98_RS07590	COG1484	DNA-dependent DNA replication
CUGBS98_RS07605	COG5002	protein histidine kinase activity
CUGBS98_RS07610	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS07620	COG0501	Belongs to the peptidase M48B family
CUGBS98_RS07625	COG1704	LemA family
CUGBS98_RS07630	COG0357	Ribosomal RNA small subunit methyltransferase G
CUGBS98_RS07635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUGBS98_RS07640	COG0569	domain protein
CUGBS98_RS07650	COG1122	ATPase activity
CUGBS98_RS07660	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CUGBS98_RS07665	COG1114	Component of the transport system for branched-chain amino acids
CUGBS98_RS07670	COG1063	alcohol dehydrogenase
CUGBS98_RS07695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUGBS98_RS07700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CUGBS98_RS07705	COG0217	transcriptional regulatory protein
CUGBS98_RS07710	COG2376	Dihydroxyacetone kinase
CUGBS98_RS07715	COG1309	transcriptional regulator
CUGBS98_RS07720	COG2376	Dihydroxyacetone kinase
CUGBS98_RS07725	COG1461	Dihydroxyacetone kinase
CUGBS98_RS07730	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CUGBS98_RS07735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS98_RS07745	COG0789	Transcriptional regulator
CUGBS98_RS07760	COG2226	methyltransferase
CUGBS98_RS07765	COG0799	negative regulation of ribosome biogenesis
CUGBS98_RS07775	COG1713	HD superfamily hydrolase involved in NAD metabolism
CUGBS98_RS07780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CUGBS98_RS07785	COG1534	Rna-binding protein
CUGBS98_RS07790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CUGBS98_RS07795	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CUGBS98_RS07820	COG0574	Belongs to the PEP-utilizing enzyme family
CUGBS98_RS07820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUGBS98_RS07830	COG0517	IMP dehydrogenase activity
CUGBS98_RS07840	COG1335	isochorismatase
CUGBS98_RS07845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUGBS98_RS07850	COG0436	Aminotransferase
CUGBS98_RS07855	COG0589	response to stress
CUGBS98_RS07860	COG0561	phosphatase activity
CUGBS98_RS07865	COG0252	asparaginase activity
CUGBS98_RS07875	COG4989	oxidoreductase activity
CUGBS98_RS07880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUGBS98_RS07885	COG3942	CHAP domain
CUGBS98_RS07885	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS98_RS07895	COG0736	holo-[acyl-carrier-protein] synthase activity
CUGBS98_RS07900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUGBS98_RS07910	COG1482	cell wall glycoprotein biosynthetic process
CUGBS98_RS07915	COG1940	carbohydrate kinase activity
CUGBS98_RS07920	COG1263	PTS System
CUGBS98_RS07920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS98_RS07920	COG2190	(PTS) system
CUGBS98_RS07925	COG1621	beta-fructofuranosidase activity
CUGBS98_RS07930	COG1609	Transcriptional regulator
CUGBS98_RS07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUGBS98_RS07945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CUGBS98_RS07965	COG2131	deaminase
CUGBS98_RS07980	COG2814	Major facilitator Superfamily
CUGBS98_RS08005	COG0629	single-stranded DNA binding
CUGBS98_RS08010	COG0360	Binds together with S18 to 16S ribosomal RNA
CUGBS98_RS08015	COG1194	a g-specific adenine glycosylase
CUGBS98_RS08025	COG3118	belongs to the thioredoxin family
CUGBS98_RS08055	COG0681	Belongs to the peptidase S26 family
CUGBS98_RS08060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUGBS98_RS08075	COG1882	Formate acetyltransferase
CUGBS98_RS08080	COG3576	pyridoxamine 5-phosphate
CUGBS98_RS08085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUGBS98_RS08100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUGBS98_RS08110	COG2814	Major facilitator Superfamily
CUGBS98_RS08115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUGBS98_RS08130	COG0142	geranyltranstransferase activity
CUGBS98_RS08135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CUGBS98_RS08140	COG4988	ABC transporter
CUGBS98_RS08145	COG1294	oxidase, subunit
CUGBS98_RS08150	COG1271	oxidase subunit
CUGBS98_RS08155	COG1252	NADH dehydrogenase
CUGBS98_RS08190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUGBS98_RS08195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS98_RS08195	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CUGBS98_RS08195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS98_RS08200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS98_RS08205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUGBS98_RS08210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUGBS98_RS08210	COG3711	transcriptional antiterminator
CUGBS98_RS08230	COG4221	oxidoreductase activity
CUGBS98_RS08250	COG1674	ftsk spoiiie
CUGBS98_RS08255	COG2946	Replication initiation factor
CUGBS98_RS08285	COG0791	NLP P60 protein
CUGBS98_RS08285	COG0741	lytic transglycosylase activity
CUGBS98_RS08325	COG0656	L-ascorbic acid biosynthetic process
CUGBS98_RS08330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUGBS98_RS08345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CUGBS98_RS08350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CUGBS98_RS08355	COG0789	Transcriptional regulator
CUGBS98_RS08370	COG2081	HI0933 family
CUGBS98_RS08395	COG0456	acetyltransferase
CUGBS98_RS08400	COG1214	PFAM Peptidase M22, glycoprotease
CUGBS98_RS08415	COG3942	CHAP domain
CUGBS98_RS08420	COG0174	glutamine synthetase
CUGBS98_RS08425	COG0789	Transcriptional regulator
CUGBS98_RS08440	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CUGBS98_RS08465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUGBS98_RS08490	COG1162	GTPase activity
CUGBS98_RS08515	COG0084	hydrolase, TatD family'
CUGBS98_RS08540	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CUGBS98_RS08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUGBS98_RS08550	COG1696	Membrane protein involved in D-alanine export
CUGBS98_RS08570	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS08580	COG3314	Sporulation integral membrane protein YlbJ
CUGBS98_RS08590	COG4175	Glycine betaine
CUGBS98_RS08590	COG3448	diguanylate cyclase activity
CUGBS98_RS08595	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CUGBS98_RS08615	COG1070	Carbohydrate kinase
CUGBS98_RS08625	COG3775	system Galactitol-specific IIC component
CUGBS98_RS08630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUGBS98_RS08640	COG1609	Transcriptional regulator
CUGBS98_RS08725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUGBS98_RS08730	COG1428	Deoxynucleoside kinase
CUGBS98_RS08740	COG0542	response to heat
CUGBS98_RS08745	COG4463	regulation of RNA biosynthetic process
CUGBS98_RS08755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CUGBS98_RS08765	COG0450	alkyl hydroperoxide reductase
CUGBS98_RS08780	COG0025	NhaP-type Na H and K H
CUGBS98_RS08790	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUGBS98_RS08795	COG3590	peptidase
CUGBS98_RS08820	COG1609	Transcriptional regulator
CUGBS98_RS08845	COG2176	DNA-directed DNA polymerase activity
CUGBS98_RS08850	COG1705	Flagellar rod assembly protein muramidase FlgJ
CUGBS98_RS08850	COG1388	LysM domain
CUGBS98_RS08865	COG4589	Belongs to the CDS family
CUGBS98_RS08870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CUGBS98_RS08875	COG1862	Preprotein translocase
CUGBS98_RS08890	COG3493	citrate carrier protein
CUGBS98_RS08895	COG3290	protein histidine kinase activity
CUGBS98_RS08900	COG4565	transcriptional regulatory protein
CUGBS98_RS08905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUGBS98_RS08915	COG3842	ATPase activity
CUGBS98_RS09000	COG0737	Belongs to the 5'-nucleotidase family
CUGBS98_RS09010	COG1363	Peptidase, m42
CUGBS98_RS09030	COG4753	response regulator
CUGBS98_RS09030	COG2207	Transcriptional regulator
CUGBS98_RS09035	COG2972	Histidine kinase
CUGBS98_RS09040	COG3716	PTS system mannose fructose sorbose family IID component
CUGBS98_RS09045	COG3715	PTS system
CUGBS98_RS09075	COG1131	(ABC) transporter
CUGBS98_RS09085	COG2274	protein secretion by the type I secretion system
CUGBS98_RS09090	COG3290	protein histidine kinase activity
CUGBS98_RS09105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUGBS98_RS09105	COG1263	PTS System
CUGBS98_RS09105	COG2190	(PTS) system
CUGBS98_RS09110	COG5002	protein histidine kinase activity
CUGBS98_RS09115	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS09130	COG0581	inorganic phosphate transmembrane transporter activity
CUGBS98_RS09135	COG0573	inorganic phosphate transmembrane transporter activity
CUGBS98_RS09150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUGBS98_RS09165	COG0789	Transcriptional regulator
CUGBS98_RS09175	COG0494	nUDIX hydrolase
CUGBS98_RS09190	COG0456	acetyltransferase
CUGBS98_RS09195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUGBS98_RS09220	COG0582	viral genome integration into host DNA
CUGBS98_RS09230	COG2946	Replication initiation factor
CUGBS98_RS09245	COG2378	regulation of single-species biofilm formation
CUGBS98_RS09250	COG0693	protein deglycase activity
CUGBS98_RS09325	COG1131	(ABC) transporter
CUGBS98_RS09360	COG1131	(ABC) transporter
CUGBS98_RS09370	COG1396	sequence-specific DNA binding
CUGBS98_RS09380	COG1694	Mazg nucleotide pyrophosphohydrolase
CUGBS98_RS09385	COG1611	Belongs to the LOG family
CUGBS98_RS09395	COG2897	thiosulfate sulfurtransferase activity
CUGBS98_RS09410	COG0371	Dehydrogenase
CUGBS98_RS09420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CUGBS98_RS09420	COG0646	methionine synthase
CUGBS98_RS09435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUGBS98_RS09450	COG2205	protein histidine kinase activity
CUGBS98_RS09450	COG2770	Histidine kinase
CUGBS98_RS09465	COG2814	Major facilitator Superfamily
CUGBS98_RS09470	COG4667	esterase of the alpha-beta hydrolase superfamily
CUGBS98_RS09485	COG4667	esterase of the alpha-beta hydrolase superfamily
CUGBS98_RS09510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUGBS98_RS09515	COG0564	pseudouridine synthase activity
CUGBS98_RS09535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUGBS98_RS09540	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CUGBS98_RS09560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CUGBS98_RS09565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUGBS98_RS09565	COG1116	anion transmembrane transporter activity
CUGBS98_RS09570	COG4120	Belongs to the binding-protein-dependent transport system permease family
CUGBS98_RS09580	COG0561	phosphatase activity
CUGBS98_RS09585	COG2514	catechol 2,3-dioxygenase activity
CUGBS98_RS09595	COG0602	queuosine metabolic process
CUGBS98_RS09615	COG1328	CTP reductase activity
CUGBS98_RS09635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUGBS98_RS09645	COG1393	Belongs to the ArsC family
CUGBS98_RS09650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CUGBS98_RS09660	COG2818	Glycosylase
CUGBS98_RS09705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS98_RS09710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS98_RS09730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUGBS98_RS09785	COG0582	viral genome integration into host DNA
CUGBS98_RS09860	COG0745	RESPONSE REGULATOR receiver
CUGBS98_RS09865	COG5002	protein histidine kinase activity
CUGBS98_RS09870	COG1288	antiporter activity
CUGBS98_RS09880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CUGBS98_RS09885	COG3852	Histidine kinase
CUGBS98_RS09890	COG0784	Response regulator, receiver
CUGBS98_RS09895	COG0517	IMP dehydrogenase activity
CUGBS98_RS09895	COG1125	glycine betaine transport
CUGBS98_RS09900	COG1174	glycine betaine transport
CUGBS98_RS09905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CUGBS98_RS09905	COG0392	lysyltransferase activity
CUGBS98_RS09915	COG3759	membrane
CUGBS98_RS10015	COG2314	TM2 domain
CUGBS98_RS10035	COG0582	viral genome integration into host DNA
CUGBS98_RS10050	COG0305	Participates in initiation and elongation during chromosome replication
CUGBS98_RS10070	COG2095	MarC family integral membrane protein
CUGBS98_RS10075	COG0482	sulfurtransferase activity
CUGBS98_RS10080	COG1760	l-serine dehydratase
CUGBS98_RS10085	COG1760	l-serine dehydratase
CUGBS98_RS10090	COG0741	lytic transglycosylase activity
CUGBS98_RS10115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUGBS98_RS10120	COG0612	Peptidase, M16
CUGBS98_RS10125	COG0612	Peptidase, M16
CUGBS98_RS10130	COG2501	S4 domain
CUGBS98_RS10150	COG0516	GMP reductase activity
CUGBS98_RS10150	COG0517	IMP dehydrogenase activity
CUGBS98_RS10160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUGBS98_RS10175	COG0454	-acetyltransferase
CUGBS98_RS10190	COG0549	Belongs to the carbamate kinase family
CUGBS98_RS10205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CUGBS98_RS10210	COG0488	(ABC) transporter
CUGBS98_RS10215	COG4485	Bacterial membrane protein, YfhO
CUGBS98_RS10235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CUGBS98_RS10240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUGBS98_RS10245	COG1475	DNA binding
