locus-tag	class	description
FOB77_RS00010	COG1464	Belongs to the NlpA lipoprotein family
FOB77_RS00015	COG2011	ABC-type metal ion transport system permease component
FOB77_RS00020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB77_RS00045	COG2223	nitrite transmembrane transporter activity
FOB77_RS00050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB77_RS00065	COG0768	penicillin binding
FOB77_RS00085	COG0772	Belongs to the SEDS family
FOB77_RS00095	COG1164	Oligoendopeptidase f
FOB77_RS00120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB77_RS00145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB77_RS00145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB77_RS00160	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB77_RS00170	COG4443	Transcriptional Coactivator p15 (PC4)
FOB77_RS00175	COG0826	peptidase U32
FOB77_RS00215	COG1983	PspC domain protein
FOB77_RS00220	COG3091	SprT-like family
FOB77_RS00225	COG2183	response to ionizing radiation
FOB77_RS00240	COG0701	Predicted permease
FOB77_RS00245	COG3689	TIGRFAM TIGR03943 family protein
FOB77_RS00250	COG0552	protein localization to endoplasmic reticulum
FOB77_RS00255	COG0561	phosphatase activity
FOB77_RS00260	COG0561	phosphatase activity
FOB77_RS00265	COG1196	nuclear chromosome segregation
FOB77_RS00275	COG2832	Protein of unknown function (DUF454)
FOB77_RS00280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOB77_RS00285	COG5002	protein histidine kinase activity
FOB77_RS00290	COG0745	RESPONSE REGULATOR receiver
FOB77_RS00295	COG1126	abc transporter atp-binding protein
FOB77_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB77_RS00305	COG0765	amino acid transport
FOB77_RS00310	COG0765	amino acid transport
FOB77_RS00335	COG0438	transferase activity, transferring glycosyl groups
FOB77_RS00350	COG1609	Transcriptional regulator
FOB77_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
FOB77_RS00375	COG1312	Catalyzes the dehydration of D-mannonate
FOB77_RS00380	COG1904	glucuronate isomerase
FOB77_RS00385	COG0800	Aldolase
FOB77_RS00395	COG2186	Transcriptional regulator
FOB77_RS00400	COG3250	beta-galactosidase activity
FOB77_RS00415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB77_RS00425	COG0583	DNA-binding transcription factor activity
FOB77_RS00435	COG0390	transport system, permease component
FOB77_RS00440	COG4619	ABC transporter
FOB77_RS00445	COG0586	Pfam SNARE associated Golgi protein
FOB77_RS00460	COG1136	(ABC) transporter
FOB77_RS00490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB77_RS00495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOB77_RS00515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB77_RS00520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB77_RS00525	COG1028	Short-chain dehydrogenase reductase Sdr
FOB77_RS00555	COG4555	ABC transporter
FOB77_RS00560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB77_RS00600	COG1316	TRANSCRIPTIONal
FOB77_RS00620	COG0148	phosphopyruvate hydratase activity
FOB77_RS00635	COG0560	Phosphoserine phosphatase
FOB77_RS00655	COG0772	Belongs to the SEDS family
FOB77_RS00675	COG5002	protein histidine kinase activity
FOB77_RS00690	COG1136	(ABC) transporter
FOB77_RS00880	COG5484	DNA packaging
FOB77_RS00880	COG3728	DNA packaging
FOB77_RS01090	COG0582	viral genome integration into host DNA
FOB77_RS01100	COG0335	large ribosomal subunit rRNA binding
FOB77_RS01105	COG0038	chloride channel
FOB77_RS01110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOB77_RS01110	COG1605	Chorismate mutase
FOB77_RS01115	COG0716	FMN binding
FOB77_RS01120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB77_RS01125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOB77_RS01130	COG0254	rRNA binding
FOB77_RS01155	COG1660	Displays ATPase and GTPase activities
FOB77_RS01180	COG0017	Asparaginyl-tRNA synthetase
FOB77_RS01185	COG0436	Aminotransferase
FOB77_RS01190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB77_RS01190	COG1199	ATP-dependent helicase activity
FOB77_RS01210	COG2177	Part of the ABC transporter FtsEX involved in
FOB77_RS01215	COG2884	Cell division ATP-binding protein ftsE
FOB77_RS01225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB77_RS01250	COG1078	dGTPase activity
FOB77_RS01295	COG2755	lipolytic protein G-D-S-L family
FOB77_RS01300	COG1307	EDD domain protein, DegV family
FOB77_RS01305	COG0497	DNA recombination
FOB77_RS01310	COG1438	arginine binding
FOB77_RS01315	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOB77_RS01325	COG1722	exodeoxyribonuclease VII activity
FOB77_RS01330	COG1570	exodeoxyribonuclease VII activity
FOB77_RS01335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB77_RS01345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB77_RS01350	COG1126	abc transporter atp-binding protein
FOB77_RS01355	COG0765	amino acid transport
FOB77_RS01360	COG4703	Protein of unknown function (DUF1797)
FOB77_RS01370	COG0542	response to heat
FOB77_RS01375	COG0494	nUDIX hydrolase
FOB77_RS01385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB77_RS01390	COG3599	regulation of cell shape
FOB77_RS01395	COG2302	S4 RNA-binding domain
FOB77_RS01400	COG0762	integral membrane protein
FOB77_RS01410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB77_RS01435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB77_RS01445	COG1217	gtp-binding protein TYPA
FOB77_RS01450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB77_RS01455	COG1940	carbohydrate kinase activity
FOB77_RS01470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB77_RS01490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB77_RS01495	COG1268	BioY protein
FOB77_RS01500	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB77_RS01505	COG1132	(ABC) transporter
FOB77_RS01510	COG1132	(ABC) transporter
FOB77_RS01520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB77_RS01525	COG4470	Protein conserved in bacteria
FOB77_RS01530	COG0737	Belongs to the 5'-nucleotidase family
FOB77_RS01535	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOB77_RS01550	COG0742	ribosomal rna small subunit methyltransferase
FOB77_RS01565	COG2502	aspartate--ammonia ligase
FOB77_RS01570	COG2315	Protein conserved in bacteria
FOB77_RS01600	COG0525	valine-tRNA ligase activity
FOB77_RS01675	COG0789	Transcriptional regulator
FOB77_RS01685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB77_RS01725	COG1216	Glycosyl transferase, family 2
FOB77_RS01725	COG1442	glycosyl transferase family 8
FOB77_RS01745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB77_RS01750	COG2137	regulation of response to DNA damage stimulus
FOB77_RS01820	COG0706	membrane insertase activity
FOB77_RS01835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB77_RS01840	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB77_RS01845	COG0457	Tetratricopeptide repeat
FOB77_RS01845	COG0705	Rhomboid family
FOB77_RS01850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB77_RS01855	COG0166	Belongs to the GPI family
FOB77_RS01870	COG1234	tRNA 3'-trailer cleavage
FOB77_RS01875	COG1268	BioY protein
FOB77_RS01895	COG5002	protein histidine kinase activity
FOB77_RS01915	COG1832	CoA-binding protein
FOB77_RS01920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB77_RS01920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB77_RS01930	COG2860	membrane
FOB77_RS01955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB77_RS01960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB77_RS01970	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOB77_RS01975	COG0195	Participates in both transcription termination and antitermination
FOB77_RS01990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB77_RS02000	COG4473	ABC transporter
FOB77_RS02005	COG1131	(ABC) transporter
FOB77_RS02020	COG0537	adenosine 5'-monophosphoramidase activity
FOB77_RS02030	COG1316	TRANSCRIPTIONal
FOB77_RS02040	COG0802	atpase or kinase
FOB77_RS02045	COG2252	PERMEase
FOB77_RS02060	COG0561	phosphatase activity
FOB77_RS02075	COG3715	PTS system
FOB77_RS02080	COG3716	PTS system mannose fructose sorbose family IID component
FOB77_RS02095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB77_RS02115	COG0439	Biotin carboxylase
FOB77_RS02130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB77_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
FOB77_RS02140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB77_RS02145	COG2070	2-Nitropropane dioxygenase
FOB77_RS02155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB77_RS02165	COG1024	Enoyl-CoA hydratase
FOB77_RS02175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB77_RS02180	COG0527	aspartate kinase activity
FOB77_RS02215	COG1040	competence protein
FOB77_RS02220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOB77_RS02225	COG1739	Uncharacterized protein family UPF0029
FOB77_RS02245	COG1882	Formate acetyltransferase
FOB77_RS02250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB77_RS02260	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB77_RS02270	COG1349	DNA-binding transcription factor activity
FOB77_RS02275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB77_RS02280	COG1098	S1 RNA binding domain
FOB77_RS02290	COG2197	response regulator
FOB77_RS02295	COG4585	Histidine kinase
FOB77_RS02305	COG0515	serine threonine protein kinase
FOB77_RS02305	COG2815	serine threonine protein kinase
FOB77_RS02315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB77_RS02315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB77_RS02320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB77_RS02325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB77_RS02335	COG0194	GDP metabolic process
FOB77_RS02345	COG2197	response regulator
FOB77_RS02350	COG4585	Histidine kinase
FOB77_RS02355	COG1131	(ABC) transporter
FOB77_RS02365	COG4372	Transposase
FOB77_RS02365	COG1418	mRNA catabolic process
FOB77_RS02370	COG1854	S-ribosylhomocysteine lyase activity
FOB77_RS02380	COG0116	Belongs to the methyltransferase superfamily
FOB77_RS02410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB77_RS02415	COG3579	cysteine-type endopeptidase activity
FOB77_RS02425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB77_RS02430	COG0492	ferredoxin-NADP+ reductase activity
FOB77_RS02440	COG1126	abc transporter atp-binding protein
FOB77_RS02455	COG0513	Belongs to the DEAD box helicase family
FOB77_RS02465	COG0768	penicillin binding
FOB77_RS02475	COG0275	rRNA processing
FOB77_RS02480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB77_RS02485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB77_RS02490	COG1263	PTS System
FOB77_RS02490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS02490	COG2190	(PTS) system
FOB77_RS02520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB77_RS02525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB77_RS02550	COG0751	glycine-tRNA ligase activity
FOB77_RS02565	COG1755	Isoprenylcysteine carboxyl methyltransferase
FOB77_RS02580	COG1695	Transcriptional regulator
FOB77_RS02625	COG0519	Catalyzes the synthesis of GMP from XMP
FOB77_RS02725	COG1732	Glycine betaine
FOB77_RS02745	COG1396	sequence-specific DNA binding
FOB77_RS02775	COG4974	Belongs to the 'phage' integrase family
FOB77_RS02785	COG0732	type I restriction modification DNA specificity domain
FOB77_RS02830	COG0582	viral genome integration into host DNA
FOB77_RS02840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB77_RS02850	COG1476	TRANSCRIPTIONal
FOB77_RS02875	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOB77_RS02880	COG0215	cysteine-tRNA ligase activity
FOB77_RS02890	COG1045	serine acetyltransferase
FOB77_RS02900	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB77_RS02910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB77_RS02915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB77_RS02920	COG3959	Transketolase, thiamine diphosphate binding domain
FOB77_RS02935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB77_RS02940	COG0366	Alpha amylase catalytic
FOB77_RS02945	COG1263	PTS System
FOB77_RS02945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS02955	COG1122	ATPase activity
FOB77_RS02960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB77_RS02965	COG0601	transmembrane transport
FOB77_RS02980	COG1346	cytolysis
FOB77_RS03000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB77_RS03005	COG0629	single-stranded DNA binding
FOB77_RS03015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB77_RS03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB77_RS03035	COG1363	Peptidase, m42
FOB77_RS03040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB77_RS03065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB77_RS03095	COG1459	type II secretion system
FOB77_RS03100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB77_RS03125	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOB77_RS03125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB77_RS03130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB77_RS03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB77_RS03145	COG1121	(ABC) transporter
FOB77_RS03155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB77_RS03185	COG4608	Belongs to the ABC transporter superfamily
FOB77_RS03190	COG0444	Belongs to the ABC transporter superfamily
FOB77_RS03195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB77_RS03200	COG0601	transmembrane transport
FOB77_RS03205	COG4166	transmembrane transport
FOB77_RS03210	COG1686	Belongs to the peptidase S11 family
FOB77_RS03215	COG1686	Belongs to the peptidase S11 family
FOB77_RS03220	COG0719	Fe-S assembly protein
FOB77_RS03230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB77_RS03235	COG0719	Fe-S assembly protein
FOB77_RS03245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB77_RS03265	COG0765	amino acid transport
FOB77_RS03270	COG1126	abc transporter atp-binding protein
FOB77_RS03285	COG1461	Dihydroxyacetone kinase
FOB77_RS03305	COG0191	fructose-bisphosphate aldolase activity
FOB77_RS03310	COG0165	Argininosuccinate lyase
FOB77_RS03315	COG0137	argininosuccinate synthase activity
FOB77_RS03320	COG2205	protein histidine kinase activity
FOB77_RS03325	COG0745	RESPONSE REGULATOR receiver
FOB77_RS03330	COG1136	(ABC) transporter
FOB77_RS03335	COG0577	efflux transmembrane transporter activity
FOB77_RS03345	COG1609	Transcriptional regulator
FOB77_RS03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB77_RS03355	COG1869	D-ribose catabolic process
FOB77_RS03360	COG1129	ABC transporter
FOB77_RS03365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB77_RS03370	COG1879	ABC-type sugar transport system periplasmic component
FOB77_RS03375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB77_RS03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB77_RS03395	COG0756	dUTP diphosphatase activity
FOB77_RS03420	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB77_RS03425	COG0668	transmembrane transport
FOB77_RS03435	COG4720	Psort location CytoplasmicMembrane, score
FOB77_RS03440	COG0351	phosphomethylpyrimidine kinase
FOB77_RS03445	COG0101	tRNA pseudouridine synthase activity
FOB77_RS03450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB77_RS03455	COG0484	heat shock protein binding
FOB77_RS03460	COG0443	Heat shock 70 kDa protein
FOB77_RS03470	COG1420	regulation of RNA biosynthetic process
FOB77_RS03475	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB77_RS03600	COG0202	RNA polymerase activity
FOB77_RS03610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB77_RS03625	COG0563	adenylate kinase activity
FOB77_RS03630	COG0201	protein transport
FOB77_RS03740	COG0534	Mate efflux family protein
FOB77_RS03750	COG1064	alcohol dehydrogenase
FOB77_RS03755	COG1012	belongs to the aldehyde dehydrogenase family
FOB77_RS03755	COG1454	alcohol dehydrogenase
FOB77_RS03760	COG2755	lipolytic protein G-D-S-L family
FOB77_RS03760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB77_RS03770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB77_RS03785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB77_RS03805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB77_RS03820	COG3458	cephalosporin-C deacetylase activity
FOB77_RS03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB77_RS03845	COG0395	ABC-type sugar transport system, permease component
FOB77_RS03850	COG1175	transmembrane transport
FOB77_RS03875	COG0138	bifunctional purine biosynthesis protein purh
FOB77_RS03885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB77_RS03900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB77_RS03910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB77_RS03915	COG0416	fatty acid biosynthetic process
FOB77_RS03930	COG0436	Aminotransferase
FOB77_RS04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB77_RS04145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB77_RS04155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB77_RS04165	COG0012	GTP binding
FOB77_RS04185	COG0592	DNA-directed DNA polymerase activity
FOB77_RS04195	COG1475	DNA binding
FOB77_RS04200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB77_RS04205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB77_RS04225	COG4485	Bacterial membrane protein, YfhO
FOB77_RS04230	COG0488	(ABC) transporter
FOB77_RS04235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB77_RS04260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB77_RS04265	COG0454	-acetyltransferase
FOB77_RS04280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB77_RS04290	COG0517	IMP dehydrogenase activity
FOB77_RS04290	COG0516	GMP reductase activity
FOB77_RS04310	COG2501	S4 domain
FOB77_RS04315	COG0612	Peptidase, M16
FOB77_RS04320	COG0612	Peptidase, M16
FOB77_RS04325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB77_RS04350	COG0741	lytic transglycosylase activity
FOB77_RS04355	COG1760	l-serine dehydratase
FOB77_RS04360	COG1760	l-serine dehydratase
FOB77_RS04365	COG0482	sulfurtransferase activity
FOB77_RS04370	COG2095	MarC family integral membrane protein
FOB77_RS04375	COG0445	tRNA wobble uridine modification
FOB77_RS04390	COG0305	Participates in initiation and elongation during chromosome replication
FOB77_RS04420	COG3759	membrane
FOB77_RS04430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOB77_RS04430	COG0392	lysyltransferase activity
FOB77_RS04435	COG1174	glycine betaine transport
FOB77_RS04445	COG0784	Response regulator, receiver
FOB77_RS04450	COG3852	Histidine kinase
FOB77_RS04455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB77_RS04465	COG1288	antiporter activity
FOB77_RS04470	COG5002	protein histidine kinase activity
FOB77_RS04475	COG0745	RESPONSE REGULATOR receiver
FOB77_RS04485	COG4974	Belongs to the 'phage' integrase family
FOB77_RS04545	COG3177	Filamentation induced by cAMP protein fic
FOB77_RS04575	COG2946	Replication initiation factor
FOB77_RS04585	COG4974	Belongs to the 'phage' integrase family
FOB77_RS04595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB77_RS04605	COG0124	histidyl-tRNA synthetase
FOB77_RS04615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB77_RS04620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB77_RS04655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB77_RS04670	COG2818	Glycosylase
FOB77_RS04675	COG1546	Belongs to the CinA family
FOB77_RS04675	COG1058	Belongs to the CinA family
FOB77_RS04680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB77_RS04685	COG1393	Belongs to the ArsC family
FOB77_RS04695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB77_RS04715	COG1328	CTP reductase activity
FOB77_RS04735	COG0602	queuosine metabolic process
FOB77_RS04745	COG2514	catechol 2,3-dioxygenase activity
FOB77_RS04750	COG0561	phosphatase activity
FOB77_RS04760	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB77_RS04765	COG1116	anion transmembrane transporter activity
FOB77_RS04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB77_RS04770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB77_RS04790	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB77_RS04795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB77_RS04815	COG0564	pseudouridine synthase activity
FOB77_RS04820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB77_RS04845	COG1442	glycosyl transferase family 8
FOB77_RS04850	COG1442	glycosyl transferase family 8
FOB77_RS04855	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB77_RS04860	COG2814	Major facilitator Superfamily
FOB77_RS04865	COG0495	leucyl-tRNA aminoacylation
FOB77_RS04875	COG2770	Histidine kinase
FOB77_RS04875	COG2205	protein histidine kinase activity
FOB77_RS04880	COG0745	RESPONSE REGULATOR receiver
FOB77_RS04895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB77_RS04905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB77_RS04910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB77_RS04910	COG0646	methionine synthase
FOB77_RS04920	COG0371	Dehydrogenase
FOB77_RS04955	COG1694	Mazg nucleotide pyrophosphohydrolase
FOB77_RS04965	COG1396	sequence-specific DNA binding
FOB77_RS05015	COG1131	(ABC) transporter
FOB77_RS05025	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB77_RS05075	COG1396	sequence-specific DNA binding
FOB77_RS05120	COG1674	ftsk spoiiie
FOB77_RS05165	COG4115	mRNA cleavage
FOB77_RS05185	COG0433	COG0433 Predicted ATPase
FOB77_RS05245	COG0582	viral genome integration into host DNA
FOB77_RS05260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB77_RS05265	COG0456	acetyltransferase
FOB77_RS05290	COG0789	Transcriptional regulator
FOB77_RS05305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB77_RS05320	COG0573	inorganic phosphate transmembrane transporter activity
FOB77_RS05325	COG0581	inorganic phosphate transmembrane transporter activity
FOB77_RS05330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB77_RS05340	COG0745	RESPONSE REGULATOR receiver
FOB77_RS05345	COG5002	protein histidine kinase activity
FOB77_RS05350	COG1263	PTS System
FOB77_RS05350	COG2190	(PTS) system
FOB77_RS05350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS05360	COG3279	Response regulator of the LytR AlgR family
FOB77_RS05370	COG1131	(ABC) transporter
FOB77_RS05400	COG3715	PTS system
FOB77_RS05405	COG3716	PTS system mannose fructose sorbose family IID component
FOB77_RS05410	COG2972	Histidine kinase
FOB77_RS05415	COG4753	response regulator
FOB77_RS05415	COG2207	Transcriptional regulator
FOB77_RS05430	COG1363	Peptidase, m42
FOB77_RS05440	COG0737	Belongs to the 5'-nucleotidase family
FOB77_RS05450	COG1490	D-aminoacyl-tRNA deacylase activity
FOB77_RS05520	COG3842	ATPase activity
FOB77_RS05530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB77_RS05535	COG4565	transcriptional regulatory protein
FOB77_RS05540	COG3290	protein histidine kinase activity
FOB77_RS05545	COG3493	citrate carrier protein
FOB77_RS05565	COG1862	Preprotein translocase
FOB77_RS05570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB77_RS05575	COG4589	Belongs to the CDS family
FOB77_RS05590	COG1388	LysM domain
FOB77_RS05590	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB77_RS05595	COG2176	DNA-directed DNA polymerase activity
FOB77_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
FOB77_RS05650	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOB77_RS05655	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS05660	COG3715	PTS system
FOB77_RS05665	COG3716	PTS system mannose fructose sorbose family IID component
FOB77_RS05675	COG1609	Transcriptional regulator
FOB77_RS05705	COG3590	peptidase
FOB77_RS05710	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB77_RS05720	COG0025	NhaP-type Na H and K H
FOB77_RS05735	COG0450	alkyl hydroperoxide reductase
FOB77_RS05745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB77_RS05760	COG4463	regulation of RNA biosynthetic process
FOB77_RS05765	COG0542	response to heat
FOB77_RS05775	COG1428	Deoxynucleoside kinase
FOB77_RS05780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB77_RS05785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB77_RS05815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB77_RS05865	COG1609	Transcriptional regulator
FOB77_RS05875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB77_RS05890	COG1070	Carbohydrate kinase
FOB77_RS05910	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOB77_RS05920	COG4175	Glycine betaine
FOB77_RS05920	COG3448	diguanylate cyclase activity
FOB77_RS05930	COG3314	Sporulation integral membrane protein YlbJ
FOB77_RS05940	COG0745	RESPONSE REGULATOR receiver
FOB77_RS05945	COG5002	protein histidine kinase activity
FOB77_RS05960	COG1696	Membrane protein involved in D-alanine export
FOB77_RS05965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB77_RS05970	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOB77_RS05995	COG0084	hydrolase, TatD family'
FOB77_RS06010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB77_RS06020	COG1162	GTPase activity
FOB77_RS06045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB77_RS06065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB77_RS06075	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOB77_RS06080	COG0126	phosphoglycerate kinase activity
FOB77_RS06090	COG0789	Transcriptional regulator
FOB77_RS06095	COG0174	glutamine synthetase
FOB77_RS06100	COG3942	CHAP domain
FOB77_RS06115	COG1214	PFAM Peptidase M22, glycoprotease
FOB77_RS06120	COG0456	acetyltransferase
FOB77_RS06125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB77_RS06150	COG2081	HI0933 family
FOB77_RS06165	COG0789	Transcriptional regulator
FOB77_RS06170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB77_RS06175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB77_RS06200	COG1252	NADH dehydrogenase
FOB77_RS06205	COG1271	oxidase subunit
FOB77_RS06210	COG1294	oxidase, subunit
FOB77_RS06215	COG4988	ABC transporter
FOB77_RS06220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB77_RS06225	COG0142	geranyltranstransferase activity
FOB77_RS06235	COG2936	dipeptidyl-peptidase activity
FOB77_RS06240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB77_RS06245	COG2814	Major facilitator Superfamily
FOB77_RS06255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB77_RS06270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB77_RS06275	COG3576	pyridoxamine 5-phosphate
FOB77_RS06280	COG1882	Formate acetyltransferase
FOB77_RS06295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB77_RS06300	COG0681	Belongs to the peptidase S26 family
FOB77_RS06305	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB77_RS06320	COG1193	negative regulation of DNA recombination
FOB77_RS06330	COG3118	belongs to the thioredoxin family
FOB77_RS06340	COG1194	a g-specific adenine glycosylase
FOB77_RS06345	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB77_RS06350	COG0629	single-stranded DNA binding
FOB77_RS06380	COG2814	Major facilitator Superfamily
FOB77_RS06390	COG0006	proline dipeptidase activity
FOB77_RS06395	COG2131	deaminase
FOB77_RS06405	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOB77_RS06430	COG1129	ABC transporter
FOB77_RS06440	COG1132	(ABC) transporter
FOB77_RS06455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB77_RS06465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB77_RS06470	COG1609	Transcriptional regulator
FOB77_RS06475	COG1621	beta-fructofuranosidase activity
FOB77_RS06480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS06480	COG1263	PTS System
FOB77_RS06480	COG2190	(PTS) system
FOB77_RS06485	COG1940	carbohydrate kinase activity
FOB77_RS06490	COG1482	cell wall glycoprotein biosynthetic process
FOB77_RS06500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB77_RS06505	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB77_RS06515	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB77_RS06515	COG3942	CHAP domain
FOB77_RS06520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB77_RS06525	COG4989	oxidoreductase activity
FOB77_RS06535	COG0252	asparaginase activity
FOB77_RS06540	COG0561	phosphatase activity
FOB77_RS06545	COG0589	response to stress
FOB77_RS06550	COG0436	Aminotransferase
FOB77_RS06555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOB77_RS06560	COG1335	isochorismatase
FOB77_RS06570	COG0517	IMP dehydrogenase activity
FOB77_RS06575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB77_RS06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB77_RS06580	COG0574	Belongs to the PEP-utilizing enzyme family
FOB77_RS06585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB77_RS06590	COG0154	amidase activity
FOB77_RS06595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB77_RS06605	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOB77_RS06610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB77_RS06615	COG1534	Rna-binding protein
FOB77_RS06620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB77_RS06625	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOB77_RS06635	COG0799	negative regulation of ribosome biogenesis
FOB77_RS06640	COG2226	methyltransferase
FOB77_RS06650	COG1323	Belongs to the UPF0348 family
FOB77_RS06655	COG0789	Transcriptional regulator
FOB77_RS06665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB77_RS06670	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOB77_RS06675	COG1461	Dihydroxyacetone kinase
FOB77_RS06680	COG2376	Dihydroxyacetone kinase
FOB77_RS06690	COG1309	transcriptional regulator
FOB77_RS06695	COG2376	Dihydroxyacetone kinase
FOB77_RS06705	COG0217	transcriptional regulatory protein
FOB77_RS06715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB77_RS06720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB77_RS06745	COG1063	alcohol dehydrogenase
FOB77_RS06750	COG1114	Component of the transport system for branched-chain amino acids
FOB77_RS06755	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOB77_RS06765	COG1122	ATPase activity
FOB77_RS06775	COG0569	domain protein
FOB77_RS06780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB77_RS06785	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB77_RS06790	COG1704	LemA family
FOB77_RS06795	COG0501	Belongs to the peptidase M48B family
FOB77_RS06805	COG0745	RESPONSE REGULATOR receiver
FOB77_RS06810	COG5002	protein histidine kinase activity
FOB77_RS06825	COG1484	DNA-dependent DNA replication
FOB77_RS06850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB77_RS06860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB77_RS06875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB77_RS06880	COG0765	amino acid transport
FOB77_RS06885	COG0706	membrane insertase activity
FOB77_RS06890	COG1254	Belongs to the acylphosphatase family
FOB77_RS06895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB77_RS06910	COG1827	regulation of RNA biosynthetic process
FOB77_RS06925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB77_RS06945	COG0582	viral genome integration into host DNA
FOB77_RS06950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOB77_RS06960	COG1187	pseudouridine synthase activity
FOB77_RS06975	COG0569	domain protein
FOB77_RS06980	COG0531	amino acid
FOB77_RS06990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB77_RS06995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB77_RS07035	COG0517	IMP dehydrogenase activity
FOB77_RS07045	COG0470	DNA polymerase III
FOB77_RS07075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB77_RS07085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB77_RS07090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB77_RS07095	COG1393	Belongs to the ArsC family
FOB77_RS07100	COG0708	Exodeoxyribonuclease III
FOB77_RS07110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB77_RS07130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB77_RS07130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB77_RS07135	COG1114	Component of the transport system for branched-chain amino acids
FOB77_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
FOB77_RS07200	COG0673	inositol 2-dehydrogenase activity
FOB77_RS07235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB77_RS07260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB77_RS07265	COG1674	ftsk spoiiie
FOB77_RS07270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB77_RS07280	COG0583	DNA-binding transcription factor activity
FOB77_RS07285	COG1473	amidohydrolase
FOB77_RS07295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB77_RS07300	COG0081	regulation of translation
FOB77_RS07305	COG0747	negative chemotaxis
FOB77_RS07310	COG0601	transmembrane transport
FOB77_RS07315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB77_RS07320	COG0444	Belongs to the ABC transporter superfamily
FOB77_RS07335	COG0233	cytoplasmic translational termination
FOB77_RS07345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB77_RS07360	COG1702	phosphate starvation-inducible protein PhoH
FOB77_RS07390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB77_RS07395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB77_RS07455	COG1396	sequence-specific DNA binding
FOB77_RS07460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB77_RS07465	COG0237	dephospho-CoA kinase activity
FOB77_RS07470	COG1131	(ABC) transporter
FOB77_RS07480	COG2814	Major facilitator Superfamily
FOB77_RS07495	COG0557	exoribonuclease II activity
FOB77_RS07500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB77_RS07505	COG1113	amino acid transport
FOB77_RS07510	COG0463	Glycosyl transferase, family 2
FOB77_RS07515	COG0346	lactoylglutathione lyase activity
FOB77_RS07520	COG0778	Nitroreductase
FOB77_RS07525	COG0656	L-ascorbic acid biosynthetic process
FOB77_RS07530	COG1187	pseudouridine synthase activity
FOB77_RS07535	COG0154	amidase activity
FOB77_RS07545	COG2309	aminopeptidase activity
FOB77_RS07570	COG1126	abc transporter atp-binding protein
FOB77_RS07575	COG0765	amino acid transport
FOB77_RS07605	COG1442	glycosyl transferase family 8
FOB77_RS07610	COG1216	Glycosyl transferase, family 2
FOB77_RS07610	COG1442	glycosyl transferase family 8
FOB77_RS07615	COG1442	glycosyl transferase family 8
FOB77_RS07620	COG1442	glycosyl transferase family 8
FOB77_RS07620	COG1216	Glycosyl transferase, family 2
FOB77_RS07625	COG1442	glycosyl transferase family 8
FOB77_RS07630	COG0201	protein transport
FOB77_RS07650	COG0653	protein targeting
FOB77_RS07655	COG0438	transferase activity, transferring glycosyl groups
FOB77_RS07675	COG3104	oligopeptide transport
FOB77_RS07680	COG3833	ABC-type maltose transport systems, permease component
FOB77_RS07685	COG1175	transmembrane transport
FOB77_RS07695	COG1609	Transcriptional regulator
FOB77_RS07700	COG1640	4-alpha-glucanotransferase
FOB77_RS07705	COG0058	SHG alpha-glucan phosphorylase activity
FOB77_RS07715	COG2271	Major facilitator Superfamily
FOB77_RS07725	COG1054	Belongs to the UPF0176 family
FOB77_RS07735	COG0004	ammonium transporteR
FOB77_RS07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB77_RS07760	COG1970	mechanosensitive ion channel activity
FOB77_RS07765	COG0358	DNA primase activity
FOB77_RS07770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB77_RS07775	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB77_RS07780	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOB77_RS07790	COG1215	transferase activity, transferring glycosyl groups
FOB77_RS07795	COG0463	Glycosyl transferase, family 2
FOB77_RS07810	COG3475	LICD family
FOB77_RS07850	COG0297	glycogen (starch) synthase activity
FOB77_RS07885	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOB77_RS07890	COG0671	phosphoesterase, PA-phosphatase related
FOB77_RS07895	COG1242	4 iron, 4 sulfur cluster binding
FOB77_RS07900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOB77_RS07905	COG1253	flavin adenine dinucleotide binding
FOB77_RS07910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB77_RS07915	COG1227	inorganic diphosphatase activity
FOB77_RS07925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB77_RS07930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB77_RS07935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB77_RS07940	COG1120	ATPase activity
FOB77_RS07945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB77_RS07950	COG2244	polysaccharide biosynthetic process
FOB77_RS07955	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB77_RS07975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB77_RS07980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB77_RS07990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB77_RS07995	COG1368	sulfuric ester hydrolase activity
FOB77_RS08000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB77_RS08010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB77_RS08015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB77_RS08020	COG3679	Belongs to the UPF0342 family
FOB77_RS08025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB77_RS08035	COG1104	cysteine desulfurase activity
FOB77_RS08060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOB77_RS08065	COG0583	DNA-binding transcription factor activity
FOB77_RS08075	COG0564	pseudouridine synthase activity
FOB77_RS08085	COG0505	Belongs to the CarA family
FOB77_RS08095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB77_RS08100	COG1136	(ABC) transporter
FOB77_RS08105	COG0577	efflux transmembrane transporter activity
FOB77_RS08110	COG0228	four-way junction DNA binding
FOB77_RS08115	COG1837	Belongs to the UPF0109 family
FOB77_RS08165	COG1388	LysM domain
FOB77_RS08165	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB77_RS08170	COG1349	DNA-binding transcription factor activity
FOB77_RS08175	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB77_RS08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB77_RS08180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB77_RS08180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB77_RS08215	COG0488	(ABC) transporter
FOB77_RS08230	COG1132	(ABC) transporter
FOB77_RS08240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB77_RS08245	COG0242	peptide deformylase activity
FOB77_RS08265	COG1132	(ABC) transporter
FOB77_RS08270	COG2357	RelA SpoT domain protein
FOB77_RS08275	COG0745	RESPONSE REGULATOR receiver
FOB77_RS08320	COG1272	protein, Hemolysin III
FOB77_RS08335	COG3425	synthase
FOB77_RS08345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB77_RS08385	COG0833	amino acid
FOB77_RS08390	COG2040	homocysteine
FOB77_RS08435	COG1674	ftsk spoiiie
FOB77_RS08465	COG4974	Belongs to the 'phage' integrase family
FOB77_RS08475	COG2176	DNA-directed DNA polymerase activity
FOB77_RS08495	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB77_RS08535	COG0534	Mate efflux family protein
FOB77_RS08545	COG0322	excinuclease ABC activity
FOB77_RS08550	COG0584	glycerophosphoryl diester phosphodiesterase
FOB77_RS08560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB77_RS08565	COG1573	uracil-dna glycosylase
FOB77_RS08595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB77_RS08610	COG0300	oxidoreductase activity
FOB77_RS08615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB77_RS08615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOB77_RS08640	COG2384	SAM-dependent methyltransferase
FOB77_RS08650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB77_RS08655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB77_RS08665	COG0135	phosphoribosylanthranilate isomerase activity
FOB77_RS08670	COG1088	dTDP-glucose 4,6-dehydratase activity
FOB77_RS08675	COG5492	domain, Protein
FOB77_RS08680	COG1051	belongs to the nudix hydrolase family
FOB77_RS08690	COG0628	permease
FOB77_RS08695	COG0457	Tetratricopeptide repeat
FOB77_RS08700	COG0028	Belongs to the TPP enzyme family
FOB77_RS08705	COG3527	Alpha-acetolactate decarboxylase
FOB77_RS08710	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FOB77_RS08745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB77_RS08760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOB77_RS08795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB77_RS08800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOB77_RS08805	COG0187	DNA topoisomerase II activity
FOB77_RS08815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB77_RS08835	COG0539	negative regulation of cytoplasmic translation
FOB77_RS08850	COG1346	cytolysis
FOB77_RS08860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOB77_RS08865	COG1115	amino acid carrier protein
FOB77_RS08890	COG2261	transglycosylase associated protein
FOB77_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
FOB77_RS08990	COG0726	polysaccharide deacetylase
FOB77_RS09005	COG2962	Rard protein
FOB77_RS09010	COG0285	dihydrofolate synthase activity
FOB77_RS09030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB77_RS09035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB77_RS09045	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB77_RS09050	COG1177	transmembrane transport
FOB77_RS09060	COG0038	chloride channel
FOB77_RS09075	COG0561	phosphatase activity
FOB77_RS09085	COG2723	6-phospho-beta-galactosidase activity
FOB77_RS09090	COG0628	permease
FOB77_RS09110	COG1104	cysteine desulfurase activity
FOB77_RS09125	COG2357	RelA SpoT domain protein
FOB77_RS09135	COG0564	pseudouridine synthase activity
FOB77_RS09140	COG0280	phosphate acetyltransferase
FOB77_RS09145	COG4221	oxidoreductase activity
FOB77_RS09160	COG0477	Major facilitator Superfamily
FOB77_RS09175	COG2233	PERMEase
FOB77_RS09185	COG1053	succinate dehydrogenase
FOB77_RS09185	COG3976	FMN-binding domain protein
FOB77_RS09185	COG0431	NADPH-dependent FMN reductase
FOB77_RS09205	COG1942	4-Oxalocrotonate Tautomerase
FOB77_RS09215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB77_RS09220	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB77_RS09250	COG1132	(ABC) transporter
FOB77_RS09260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB77_RS09265	COG4684	Psort location CytoplasmicMembrane, score
FOB77_RS09270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB77_RS09320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB77_RS09335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB77_RS09345	COG0488	(ABC) transporter
FOB77_RS09360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB77_RS09365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOB77_RS09375	COG0505	Belongs to the CarA family
FOB77_RS09510	COG3275	phosphorelay sensor kinase activity
FOB77_RS09515	COG3279	Response regulator of the LytR AlgR family
FOB77_RS09520	COG1966	Carbon starvation protein
FOB77_RS09525	COG1376	ErfK ybiS ycfS ynhG family protein
FOB77_RS09530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB77_RS09540	COG0110	maltose O-acetyltransferase activity
FOB77_RS09545	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB77_RS09550	COG4605	iron ion homeostasis
FOB77_RS09555	COG4604	ABC transporter, ATP-binding protein
FOB77_RS09560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB77_RS09565	COG0758	DNA mediated transformation
FOB77_RS09570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB77_RS09575	COG1136	(ABC) transporter
FOB77_RS09605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB77_RS09610	COG0196	riboflavin kinase activity
FOB77_RS09620	COG4476	Belongs to the UPF0223 family
FOB77_RS09625	COG0483	inositol monophosphate 1-phosphatase activity
FOB77_RS09630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB77_RS09630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB77_RS09640	COG0573	inorganic phosphate transmembrane transporter activity
FOB77_RS09645	COG0581	inorganic phosphate transmembrane transporter activity
FOB77_RS09650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB77_RS09655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB77_RS09660	COG0704	Plays a role in the regulation of phosphate uptake
FOB77_RS09670	COG0745	RESPONSE REGULATOR receiver
FOB77_RS09675	COG5002	protein histidine kinase activity
FOB77_RS09680	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOB77_RS09685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB77_RS09720	COG1131	(ABC) transporter
FOB77_RS09750	COG1131	(ABC) transporter
FOB77_RS09755	COG1132	(ABC) transporter
FOB77_RS09770	COG0488	(ABC) transporter
FOB77_RS09830	COG4974	Belongs to the 'phage' integrase family
FOB77_RS09835	COG5002	protein histidine kinase activity
FOB77_RS09840	COG0745	RESPONSE REGULATOR receiver
FOB77_RS09850	COG1136	(ABC) transporter
FOB77_RS09865	COG1464	Belongs to the NlpA lipoprotein family
FOB77_RS09875	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FOB77_RS09880	COG2188	Transcriptional regulator
FOB77_RS09890	COG0582	viral genome integration into host DNA
FOB77_RS09945	COG0741	lytic transglycosylase activity
FOB77_RS09945	COG0791	NLP P60 protein
FOB77_RS09995	COG2946	Replication initiation factor
FOB77_RS10000	COG1674	ftsk spoiiie
FOB77_RS10030	COG0346	lactoylglutathione lyase activity
FOB77_RS10035	COG3764	Sortase (surface protein transpeptidase)
FOB77_RS10055	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOB77_RS10060	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOB77_RS10065	COG3845	ABC transporter
FOB77_RS10070	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB77_RS10080	COG2813	Specifically methylates the guanine in position
FOB77_RS10085	COG1072	(Pantothenic acid kinase))
FOB77_RS10100	COG1126	abc transporter atp-binding protein
FOB77_RS10105	COG0765	amino acid transport
FOB77_RS10110	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB77_RS10115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB77_RS10130	COG0469	pyruvate kinase activity
FOB77_RS10135	COG0205	6-phosphofructokinase activity
FOB77_RS10145	COG1725	Transcriptional regulator
FOB77_RS10150	COG1131	(ABC) transporter
FOB77_RS10180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOB77_RS10190	COG0456	acetyltransferase
FOB77_RS10195	COG1418	mRNA catabolic process
FOB77_RS10205	COG0481	GTPase activity
FOB77_RS10225	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOB77_RS10230	COG1518	maintenance of DNA repeat elements
FOB77_RS10235	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FOB77_RS10245	COG0647	UMP catabolic process
FOB77_RS10255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB77_RS10280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOB77_RS10285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB77_RS10290	COG3442	glutamine amidotransferase
FOB77_RS10295	COG0095	Lipoate-protein ligase
FOB77_RS10305	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB77_RS10310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB77_RS10310	COG0022	dehydrogenase e1 component
FOB77_RS10315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOB77_RS10320	COG0488	(ABC) transporter
FOB77_RS10325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB77_RS10335	COG1074	ATP-dependent DNA helicase activity
FOB77_RS10340	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOB77_RS10345	COG2321	neutral zinc metallopeptidase
FOB77_RS10350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB77_RS10350	COG0072	phenylalanine-tRNA ligase activity
FOB77_RS10360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB77_RS10375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB77_RS10385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB77_RS10395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB77_RS10415	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB77_RS10425	COG0297	glycogen (starch) synthase activity
FOB77_RS10430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB77_RS10435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB77_RS10440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB77_RS10445	COG1523	belongs to the glycosyl hydrolase 13 family
FOB77_RS10450	COG1597	lipid kinase activity
FOB77_RS10455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB77_RS10460	COG4708	membrane
FOB77_RS10475	COG0024	Methionine aminopeptidase
FOB77_RS10480	COG4109	DRTGG domain
FOB77_RS10490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB77_RS10495	COG0352	thiamine-phosphate diphosphorylase activity
FOB77_RS10500	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOB77_RS10510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB77_RS10520	COG1122	ATPase activity
FOB77_RS10525	COG4721	ABC-type cobalt transport system, permease component
FOB77_RS10550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB77_RS10555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOB77_RS10555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOB77_RS10565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB77_RS10570	COG1956	GAF domain-containing protein
FOB77_RS10580	COG0513	Belongs to the DEAD box helicase family
FOB77_RS10585	COG0726	polysaccharide deacetylase
FOB77_RS10590	COG1012	belongs to the aldehyde dehydrogenase family
FOB77_RS10605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB77_RS10610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB77_RS10615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB77_RS10630	COG1476	TRANSCRIPTIONal
FOB77_RS10640	COG1442	glycosyl transferase family 8
FOB77_RS10650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB77_RS10655	COG4894	glucomannan catabolic process
FOB77_RS10660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB77_RS10665	COG4122	O-methyltransferase activity
FOB77_RS10670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB77_RS10675	COG1164	Oligoendopeptidase f
FOB77_RS10695	COG1187	pseudouridine synthase activity
FOB77_RS10700	COG0435	Glutathione S-transferase
FOB77_RS10705	COG0363	glucosamine-6-phosphate deaminase activity
FOB77_RS10715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB77_RS10720	COG1846	Transcriptional regulator
FOB77_RS10730	COG2610	gluconate transmembrane transporter activity
FOB77_RS10735	COG1929	Belongs to the glycerate kinase type-1 family
FOB77_RS10740	COG3835	regulator
FOB77_RS10750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB77_RS10750	COG1263	PTS System
FOB77_RS10750	COG2190	(PTS) system
FOB77_RS10755	COG3711	transcriptional antiterminator
FOB77_RS10760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB77_RS10770	COG2226	methyltransferase
FOB77_RS10775	COG0657	acetylesterase activity
FOB77_RS10780	COG1609	Transcriptional regulator
FOB77_RS10785	COG0561	phosphatase activity
FOB77_RS10790	COG0658	competence protein
FOB77_RS10790	COG2333	competence protein COMEC
FOB77_RS10795	COG1555	photosystem II stabilization
FOB77_RS10795	COG1596	polysaccharide export
FOB77_RS10800	COG0204	Acyl-transferase
FOB77_RS10805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)