locus-tag	class	description
AV644_RS00010	COG0592	DNA-directed DNA polymerase activity
AV644_RS00030	COG0012	GTP binding
AV644_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV644_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AV644_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV644_RS00265	COG0436	Aminotransferase
AV644_RS00280	COG0416	fatty acid biosynthetic process
AV644_RS00285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV644_RS00290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AV644_RS00295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV644_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AV644_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV644_RS00320	COG0138	bifunctional purine biosynthesis protein purh
AV644_RS00335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AV644_RS00345	COG1175	transmembrane transport
AV644_RS00350	COG0395	ABC-type sugar transport system, permease component
AV644_RS00365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV644_RS00375	COG3458	cephalosporin-C deacetylase activity
AV644_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AV644_RS00405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV644_RS00420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV644_RS00430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AV644_RS00430	COG2755	lipolytic protein G-D-S-L family
AV644_RS00435	COG1454	alcohol dehydrogenase
AV644_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
AV644_RS00440	COG1064	alcohol dehydrogenase
AV644_RS00450	COG0534	Mate efflux family protein
AV644_RS00560	COG0201	protein transport
AV644_RS00565	COG0563	adenylate kinase activity
AV644_RS00580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AV644_RS00590	COG0202	RNA polymerase activity
AV644_RS00735	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV644_RS00750	COG0443	Heat shock 70 kDa protein
AV644_RS00760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV644_RS00770	COG0351	phosphomethylpyrimidine kinase
AV644_RS00775	COG4720	Psort location CytoplasmicMembrane, score
AV644_RS00785	COG0668	transmembrane transport
AV644_RS00815	COG0756	dUTP diphosphatase activity
AV644_RS00830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV644_RS00835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV644_RS00840	COG1879	ABC-type sugar transport system periplasmic component
AV644_RS00845	COG1172	Belongs to the binding-protein-dependent transport system permease family
AV644_RS00860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV644_RS00865	COG1609	Transcriptional regulator
AV644_RS00875	COG0577	efflux transmembrane transporter activity
AV644_RS00880	COG1136	(ABC) transporter
AV644_RS00885	COG0745	RESPONSE REGULATOR receiver
AV644_RS00890	COG5002	protein histidine kinase activity
AV644_RS00905	COG0191	fructose-bisphosphate aldolase activity
AV644_RS00925	COG1461	Dihydroxyacetone kinase
AV644_RS00945	COG1126	abc transporter atp-binding protein
AV644_RS00950	COG0765	amino acid transport
AV644_RS00970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV644_RS00980	COG0719	Fe-S assembly protein
AV644_RS00985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV644_RS00995	COG0719	Fe-S assembly protein
AV644_RS01000	COG1686	Belongs to the peptidase S11 family
AV644_RS01005	COG1686	Belongs to the peptidase S11 family
AV644_RS01010	COG4166	transmembrane transport
AV644_RS01015	COG0601	transmembrane transport
AV644_RS01020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV644_RS01025	COG0444	Belongs to the ABC transporter superfamily
AV644_RS01030	COG4608	Belongs to the ABC transporter superfamily
AV644_RS01070	COG1121	(ABC) transporter
AV644_RS01075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AV644_RS01090	COG4499	WXG100 protein secretion system (Wss), protein YukC
AV644_RS01090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV644_RS01115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV644_RS01120	COG1459	type II secretion system
AV644_RS01165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AV644_RS01170	COG1363	Peptidase, m42
AV644_RS01185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV644_RS01190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV644_RS01205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV644_RS01225	COG1346	cytolysis
AV644_RS01240	COG0601	transmembrane transport
AV644_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV644_RS01250	COG1122	ATPase activity
AV644_RS01260	COG1263	PTS System
AV644_RS01260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS01265	COG0366	Alpha amylase catalytic
AV644_RS01270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV644_RS01285	COG3959	Transketolase, thiamine diphosphate binding domain
AV644_RS01290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AV644_RS01295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV644_RS01315	COG1045	serine acetyltransferase
AV644_RS01330	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AV644_RS01365	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AV644_RS01375	COG4974	Belongs to the 'phage' integrase family
AV644_RS01395	COG3942	CHAP domain
AV644_RS01395	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV644_RS01410	COG0433	COG0433 Predicted ATPase
AV644_RS01450	COG1674	ftsk spoiiie
AV644_RS01485	COG1396	sequence-specific DNA binding
AV644_RS01520	COG1132	(ABC) transporter
AV644_RS01570	COG1396	sequence-specific DNA binding
AV644_RS01575	COG2814	Major facilitator Superfamily
AV644_RS01585	COG1732	Glycine betaine
AV644_RS01720	COG0519	Catalyzes the synthesis of GMP from XMP
AV644_RS01765	COG1695	Transcriptional regulator
AV644_RS01780	COG1755	Isoprenylcysteine carboxyl methyltransferase
AV644_RS01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV644_RS01825	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV644_RS01845	COG1131	(ABC) transporter
AV644_RS01855	COG1263	PTS System
AV644_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS01855	COG2190	(PTS) system
AV644_RS01860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV644_RS01880	COG0768	penicillin binding
AV644_RS01890	COG0513	Belongs to the DEAD box helicase family
AV644_RS01905	COG1126	abc transporter atp-binding protein
AV644_RS01915	COG0492	ferredoxin-NADP+ reductase activity
AV644_RS01920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AV644_RS01930	COG3579	cysteine-type endopeptidase activity
AV644_RS01935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV644_RS01965	COG0116	Belongs to the methyltransferase superfamily
AV644_RS01975	COG1854	S-ribosylhomocysteine lyase activity
AV644_RS01980	COG1418	mRNA catabolic process
AV644_RS01980	COG4372	Transposase
AV644_RS01990	COG1131	(ABC) transporter
AV644_RS02000	COG4585	Histidine kinase
AV644_RS02005	COG2197	response regulator
AV644_RS02015	COG0194	GDP metabolic process
AV644_RS02025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV644_RS02030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV644_RS02035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV644_RS02035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV644_RS02045	COG2815	serine threonine protein kinase
AV644_RS02045	COG0515	serine threonine protein kinase
AV644_RS02055	COG4585	Histidine kinase
AV644_RS02060	COG2197	response regulator
AV644_RS02070	COG1098	S1 RNA binding domain
AV644_RS02075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AV644_RS02080	COG1349	DNA-binding transcription factor activity
AV644_RS02090	COG1447	Phosphotransferase system cellobiose-specific component IIA
AV644_RS02100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AV644_RS02105	COG1882	Formate acetyltransferase
AV644_RS02125	COG1739	Uncharacterized protein family UPF0029
AV644_RS02130	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AV644_RS02135	COG1040	competence protein
AV644_RS02170	COG0527	aspartate kinase activity
AV644_RS02175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV644_RS02180	COG1024	Enoyl-CoA hydratase
AV644_RS02190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV644_RS02200	COG2070	2-Nitropropane dioxygenase
AV644_RS02205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AV644_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
AV644_RS02215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV644_RS02230	COG0439	Biotin carboxylase
AV644_RS02255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AV644_RS02270	COG3716	PTS system mannose fructose sorbose family IID component
AV644_RS02275	COG3715	PTS system
AV644_RS02290	COG0561	phosphatase activity
AV644_RS02305	COG2252	PERMEase
AV644_RS02310	COG0802	atpase or kinase
AV644_RS02320	COG1316	TRANSCRIPTIONal
AV644_RS02330	COG0537	adenosine 5'-monophosphoramidase activity
AV644_RS02345	COG1131	(ABC) transporter
AV644_RS02350	COG4473	ABC transporter
AV644_RS02360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV644_RS02375	COG0195	Participates in both transcription termination and antitermination
AV644_RS02380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AV644_RS02390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AV644_RS02395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AV644_RS02420	COG2860	membrane
AV644_RS02430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV644_RS02430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV644_RS02435	COG1832	CoA-binding protein
AV644_RS02455	COG5002	protein histidine kinase activity
AV644_RS02475	COG1268	BioY protein
AV644_RS02480	COG1234	tRNA 3'-trailer cleavage
AV644_RS02495	COG0166	Belongs to the GPI family
AV644_RS02500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AV644_RS02505	COG0705	Rhomboid family
AV644_RS02505	COG0457	Tetratricopeptide repeat
AV644_RS02510	COG1744	ABC transporter substrate-binding protein PnrA-like
AV644_RS02515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AV644_RS02530	COG0706	membrane insertase activity
AV644_RS02590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AV644_RS02600	COG2153	protein acetylation
AV644_RS02610	COG1216	Glycosyl transferase, family 2
AV644_RS02610	COG1442	glycosyl transferase family 8
AV644_RS02655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV644_RS02665	COG0789	Transcriptional regulator
AV644_RS02680	COG0656	L-ascorbic acid biosynthetic process
AV644_RS02730	COG2226	methyltransferase
AV644_RS02740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV644_RS02745	COG3414	Phosphotransferase system galactitol-specific IIB component
AV644_RS02750	COG3775	system Galactitol-specific IIC component
AV644_RS02755	COG0235	Class ii aldolase
AV644_RS02765	COG3775	system Galactitol-specific IIC component
AV644_RS02770	COG3414	Phosphotransferase system galactitol-specific IIB component
AV644_RS02775	COG2207	Transcriptional regulator
AV644_RS02785	COG1175	transmembrane transport
AV644_RS02790	COG0395	ABC-type sugar transport system, permease component
AV644_RS02800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AV644_RS02810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV644_RS02815	COG2017	converts alpha-aldose to the beta-anomer
AV644_RS02835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV644_RS02845	COG0525	valine-tRNA ligase activity
AV644_RS02855	COG0673	inositol 2-dehydrogenase activity
AV644_RS02865	COG2315	Protein conserved in bacteria
AV644_RS02880	COG0742	ribosomal rna small subunit methyltransferase
AV644_RS02895	COG3480	Lon protease (S16) C-terminal proteolytic domain
AV644_RS02900	COG0737	Belongs to the 5'-nucleotidase family
AV644_RS02905	COG4470	Protein conserved in bacteria
AV644_RS02920	COG1132	(ABC) transporter
AV644_RS02925	COG1132	(ABC) transporter
AV644_RS02930	COG0512	Glutamine amidotransferase of anthranilate synthase
AV644_RS02950	COG0183	Belongs to the thiolase family
AV644_RS02960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV644_RS02975	COG1940	carbohydrate kinase activity
AV644_RS02980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV644_RS02985	COG1217	gtp-binding protein TYPA
AV644_RS03020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AV644_RS03030	COG0762	integral membrane protein
AV644_RS03035	COG2302	S4 RNA-binding domain
AV644_RS03040	COG3599	regulation of cell shape
AV644_RS03055	COG0494	nUDIX hydrolase
AV644_RS03060	COG0542	response to heat
AV644_RS03065	COG4703	Protein of unknown function (DUF1797)
AV644_RS03070	COG0765	amino acid transport
AV644_RS03075	COG1126	abc transporter atp-binding protein
AV644_RS03080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV644_RS03090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV644_RS03100	COG1722	exodeoxyribonuclease VII activity
AV644_RS03110	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AV644_RS03115	COG1438	arginine binding
AV644_RS03120	COG0497	DNA recombination
AV644_RS03125	COG1307	EDD domain protein, DegV family
AV644_RS03130	COG2755	lipolytic protein G-D-S-L family
AV644_RS03175	COG1078	dGTPase activity
AV644_RS03200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV644_RS03210	COG2884	Cell division ATP-binding protein ftsE
AV644_RS03215	COG2177	Part of the ABC transporter FtsEX involved in
AV644_RS03235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV644_RS03235	COG1199	ATP-dependent helicase activity
AV644_RS03240	COG0436	Aminotransferase
AV644_RS03245	COG0017	Asparaginyl-tRNA synthetase
AV644_RS03265	COG1660	Displays ATPase and GTPase activities
AV644_RS03290	COG0254	rRNA binding
AV644_RS03295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AV644_RS03300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV644_RS03305	COG0716	FMN binding
AV644_RS03310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AV644_RS03310	COG1605	Chorismate mutase
AV644_RS03315	COG0038	chloride channel
AV644_RS03320	COG0335	large ribosomal subunit rRNA binding
AV644_RS03360	COG1136	(ABC) transporter
AV644_RS03375	COG5002	protein histidine kinase activity
AV644_RS03395	COG0772	Belongs to the SEDS family
AV644_RS03415	COG0560	Phosphoserine phosphatase
AV644_RS03430	COG0148	phosphopyruvate hydratase activity
AV644_RS03450	COG1316	TRANSCRIPTIONal
AV644_RS03495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV644_RS03495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV644_RS03540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AV644_RS03560	COG0270	DNA (cytosine-5-)-methyltransferase activity
AV644_RS03610	COG4695	Portal protein
AV644_RS03615	COG0740	serine-type endopeptidase activity
AV644_RS03680	COG1388	LysM domain
AV644_RS03680	COG0860	N-Acetylmuramoyl-L-alanine amidase
AV644_RS03700	COG0640	Transcriptional regulator
AV644_RS03705	COG1902	pentaerythritol trinitrate reductase activity
AV644_RS03715	COG3700	Belongs to the class B bacterial acid phosphatase family
AV644_RS03820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV644_RS03825	COG4555	ABC transporter
AV644_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
AV644_RS03855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV644_RS03860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV644_RS03880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AV644_RS03885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV644_RS03905	COG3064	Membrane
AV644_RS03905	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV644_RS03920	COG3590	peptidase
AV644_RS03925	COG3590	peptidase
AV644_RS03970	COG1136	(ABC) transporter
AV644_RS03985	COG0586	Pfam SNARE associated Golgi protein
AV644_RS03990	COG4619	ABC transporter
AV644_RS03995	COG0390	transport system, permease component
AV644_RS04005	COG0583	DNA-binding transcription factor activity
AV644_RS04015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV644_RS04020	COG2211	Major facilitator Superfamily
AV644_RS04030	COG3250	beta-galactosidase activity
AV644_RS04035	COG2186	Transcriptional regulator
AV644_RS04040	COG0800	Aldolase
AV644_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
AV644_RS04075	COG1609	Transcriptional regulator
AV644_RS04090	COG0438	transferase activity, transferring glycosyl groups
AV644_RS04115	COG0765	amino acid transport
AV644_RS04120	COG0765	amino acid transport
AV644_RS04125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV644_RS04130	COG1126	abc transporter atp-binding protein
AV644_RS04135	COG0745	RESPONSE REGULATOR receiver
AV644_RS04140	COG5002	protein histidine kinase activity
AV644_RS04145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AV644_RS04150	COG2832	Protein of unknown function (DUF454)
AV644_RS04160	COG1196	nuclear chromosome segregation
AV644_RS04165	COG0561	phosphatase activity
AV644_RS04170	COG0561	phosphatase activity
AV644_RS04175	COG0552	protein localization to endoplasmic reticulum
AV644_RS04180	COG3689	TIGRFAM TIGR03943 family protein
AV644_RS04185	COG0701	Predicted permease
AV644_RS04200	COG2183	response to ionizing radiation
AV644_RS04205	COG3091	SprT-like family
AV644_RS04210	COG1983	PspC domain protein
AV644_RS04250	COG0826	peptidase U32
AV644_RS04255	COG4443	Transcriptional Coactivator p15 (PC4)
AV644_RS04265	COG1914	H( )-stimulated, divalent metal cation uptake system
AV644_RS04280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AV644_RS04280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AV644_RS04305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV644_RS04330	COG1164	Oligoendopeptidase f
AV644_RS04340	COG0772	Belongs to the SEDS family
AV644_RS04360	COG0768	penicillin binding
AV644_RS04375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV644_RS04380	COG2223	nitrite transmembrane transporter activity
AV644_RS04405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AV644_RS04410	COG2011	ABC-type metal ion transport system permease component
AV644_RS04415	COG1464	Belongs to the NlpA lipoprotein family
AV644_RS04420	COG0513	Belongs to the DEAD box helicase family
AV644_RS04430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AV644_RS04435	COG0204	Acyl-transferase
AV644_RS04440	COG1596	polysaccharide export
AV644_RS04440	COG1555	photosystem II stabilization
AV644_RS04445	COG2333	competence protein COMEC
AV644_RS04445	COG0658	competence protein
AV644_RS04450	COG0561	phosphatase activity
AV644_RS04455	COG1609	Transcriptional regulator
AV644_RS04460	COG0657	acetylesterase activity
AV644_RS04465	COG2226	methyltransferase
AV644_RS04475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV644_RS04480	COG3711	transcriptional antiterminator
AV644_RS04485	COG1263	PTS System
AV644_RS04485	COG2190	(PTS) system
AV644_RS04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS04495	COG3835	regulator
AV644_RS04500	COG1929	Belongs to the glycerate kinase type-1 family
AV644_RS04505	COG2610	gluconate transmembrane transporter activity
AV644_RS04515	COG1846	Transcriptional regulator
AV644_RS04530	COG0363	glucosamine-6-phosphate deaminase activity
AV644_RS04535	COG0435	Glutathione S-transferase
AV644_RS04540	COG1187	pseudouridine synthase activity
AV644_RS04565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV644_RS04570	COG4122	O-methyltransferase activity
AV644_RS04580	COG4894	glucomannan catabolic process
AV644_RS04590	COG1811	Na channel or pump
AV644_RS04595	COG1442	glycosyl transferase family 8
AV644_RS04610	COG1476	TRANSCRIPTIONal
AV644_RS04625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV644_RS04630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV644_RS04635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV644_RS04650	COG1012	belongs to the aldehyde dehydrogenase family
AV644_RS04655	COG0726	polysaccharide deacetylase
AV644_RS04670	COG1956	GAF domain-containing protein
AV644_RS04675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV644_RS04685	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AV644_RS04685	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AV644_RS04715	COG4721	ABC-type cobalt transport system, permease component
AV644_RS04720	COG1122	ATPase activity
AV644_RS04730	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AV644_RS04750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AV644_RS04760	COG4109	DRTGG domain
AV644_RS04765	COG0024	Methionine aminopeptidase
AV644_RS04775	COG2246	polysaccharide biosynthetic process
AV644_RS04780	COG4708	membrane
AV644_RS04790	COG1597	lipid kinase activity
AV644_RS04795	COG1523	belongs to the glycosyl hydrolase 13 family
AV644_RS04890	COG0072	phenylalanine-tRNA ligase activity
AV644_RS04890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV644_RS04895	COG2321	neutral zinc metallopeptidase
AV644_RS04920	COG0488	(ABC) transporter
AV644_RS04925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV644_RS04930	COG0022	dehydrogenase e1 component
AV644_RS04930	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV644_RS04935	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV644_RS04945	COG0095	Lipoate-protein ligase
AV644_RS04950	COG3442	glutamine amidotransferase
AV644_RS04955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV644_RS04960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AV644_RS04985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV644_RS04995	COG0647	UMP catabolic process
AV644_RS05005	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AV644_RS05010	COG1518	maintenance of DNA repeat elements
AV644_RS05015	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AV644_RS05040	COG0481	GTPase activity
AV644_RS05055	COG1418	mRNA catabolic process
AV644_RS05060	COG0456	acetyltransferase
AV644_RS05070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AV644_RS05100	COG1131	(ABC) transporter
AV644_RS05105	COG1725	Transcriptional regulator
AV644_RS05115	COG0205	6-phosphofructokinase activity
AV644_RS05120	COG0469	pyruvate kinase activity
AV644_RS05135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV644_RS05140	COG2824	Alkylphosphonate utilization operon protein PhnA
AV644_RS05145	COG0765	amino acid transport
AV644_RS05150	COG1126	abc transporter atp-binding protein
AV644_RS05165	COG1072	(Pantothenic acid kinase))
AV644_RS05170	COG2813	Specifically methylates the guanine in position
AV644_RS05180	COG1744	ABC transporter substrate-binding protein PnrA-like
AV644_RS05185	COG3845	ABC transporter
AV644_RS05190	COG4603	Belongs to the binding-protein-dependent transport system permease family
AV644_RS05195	COG1079	Belongs to the binding-protein-dependent transport system permease family
AV644_RS05215	COG3764	Sortase (surface protein transpeptidase)
AV644_RS05220	COG0346	lactoylglutathione lyase activity
AV644_RS05240	COG2188	Transcriptional regulator
AV644_RS05245	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AV644_RS05255	COG1464	Belongs to the NlpA lipoprotein family
AV644_RS05270	COG1136	(ABC) transporter
AV644_RS05280	COG0745	RESPONSE REGULATOR receiver
AV644_RS05285	COG5002	protein histidine kinase activity
AV644_RS05290	COG4974	Belongs to the 'phage' integrase family
AV644_RS05295	COG4166	transmembrane transport
AV644_RS05310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV644_RS05315	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AV644_RS05320	COG5002	protein histidine kinase activity
AV644_RS05325	COG0745	RESPONSE REGULATOR receiver
AV644_RS05335	COG0704	Plays a role in the regulation of phosphate uptake
AV644_RS05340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV644_RS05345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV644_RS05350	COG0581	inorganic phosphate transmembrane transporter activity
AV644_RS05355	COG0573	inorganic phosphate transmembrane transporter activity
AV644_RS05365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV644_RS05365	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AV644_RS05370	COG0483	inositol monophosphate 1-phosphatase activity
AV644_RS05375	COG4476	Belongs to the UPF0223 family
AV644_RS05385	COG0196	riboflavin kinase activity
AV644_RS05390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV644_RS05420	COG1136	(ABC) transporter
AV644_RS05425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AV644_RS05430	COG0758	DNA mediated transformation
AV644_RS05435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AV644_RS05440	COG4604	ABC transporter, ATP-binding protein
AV644_RS05445	COG4605	iron ion homeostasis
AV644_RS05450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV644_RS05455	COG0110	maltose O-acetyltransferase activity
AV644_RS05465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV644_RS05470	COG1376	ErfK ybiS ycfS ynhG family protein
AV644_RS05475	COG1966	Carbon starvation protein
AV644_RS05480	COG3279	Response regulator of the LytR AlgR family
AV644_RS05485	COG3275	phosphorelay sensor kinase activity
AV644_RS05595	COG0505	Belongs to the CarA family
AV644_RS05605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AV644_RS05625	COG0488	(ABC) transporter
AV644_RS05635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV644_RS05645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV644_RS05685	COG0095	Lipoate-protein ligase
AV644_RS05695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV644_RS05700	COG4684	Psort location CytoplasmicMembrane, score
AV644_RS05705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV644_RS05715	COG1132	(ABC) transporter
AV644_RS05745	COG2890	protein-(glutamine-N5) methyltransferase activity
AV644_RS05760	COG1942	4-Oxalocrotonate Tautomerase
AV644_RS05775	COG0431	NADPH-dependent FMN reductase
AV644_RS05775	COG1053	succinate dehydrogenase
AV644_RS05775	COG3976	FMN-binding domain protein
AV644_RS05785	COG2233	PERMEase
AV644_RS05800	COG0477	Major facilitator Superfamily
AV644_RS05815	COG4221	oxidoreductase activity
AV644_RS05820	COG0280	phosphate acetyltransferase
AV644_RS05825	COG0564	pseudouridine synthase activity
AV644_RS05830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AV644_RS05835	COG2357	RelA SpoT domain protein
AV644_RS05850	COG1104	cysteine desulfurase activity
AV644_RS05860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AV644_RS05865	COG2003	Belongs to the UPF0758 family
AV644_RS05870	COG0628	permease
AV644_RS05875	COG2723	6-phospho-beta-galactosidase activity
AV644_RS05885	COG0561	phosphatase activity
AV644_RS05900	COG0038	chloride channel
AV644_RS05910	COG1177	transmembrane transport
AV644_RS05915	COG1176	ABC-type spermidine putrescine transport system, permease component I
AV644_RS05925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV644_RS05930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AV644_RS05950	COG0285	dihydrofolate synthase activity
AV644_RS05955	COG2962	Rard protein
AV644_RS05970	COG0726	polysaccharide deacetylase
AV644_RS05975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV644_RS05995	COG1012	belongs to the aldehyde dehydrogenase family
AV644_RS06070	COG2261	transglycosylase associated protein
AV644_RS06095	COG1115	amino acid carrier protein
AV644_RS06100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AV644_RS06110	COG1346	cytolysis
AV644_RS06125	COG0539	negative regulation of cytoplasmic translation
AV644_RS06145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV644_RS06155	COG0187	DNA topoisomerase II activity
AV644_RS06160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV644_RS06165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV644_RS06190	COG2089	acid synthase
AV644_RS06205	COG1216	Glycosyl transferase, family 2
AV644_RS06210	COG1215	transferase activity, transferring glycosyl groups
AV644_RS06225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AV644_RS06230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV644_RS06250	COG1316	TRANSCRIPTIONal
AV644_RS06275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AV644_RS06290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV644_RS06325	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AV644_RS06330	COG3527	Alpha-acetolactate decarboxylase
AV644_RS06335	COG0028	Belongs to the TPP enzyme family
AV644_RS06340	COG0457	Tetratricopeptide repeat
AV644_RS06345	COG0628	permease
AV644_RS06355	COG1051	belongs to the nudix hydrolase family
AV644_RS06360	COG5492	domain, Protein
AV644_RS06365	COG5492	domain, Protein
AV644_RS06370	COG1088	dTDP-glucose 4,6-dehydratase activity
AV644_RS06380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AV644_RS06385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV644_RS06395	COG2384	SAM-dependent methyltransferase
AV644_RS06420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AV644_RS06420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AV644_RS06425	COG0300	oxidoreductase activity
AV644_RS06440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV644_RS06470	COG1573	uracil-dna glycosylase
AV644_RS06475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AV644_RS06485	COG0584	glycerophosphoryl diester phosphodiesterase
AV644_RS06490	COG0322	excinuclease ABC activity
AV644_RS06500	COG0534	Mate efflux family protein
AV644_RS06540	COG2801	Transposase and inactivated derivatives
AV644_RS06560	COG0803	Belongs to the bacterial solute-binding protein 9 family
AV644_RS06585	COG2176	DNA-directed DNA polymerase activity
AV644_RS06610	COG2040	homocysteine
AV644_RS06615	COG0833	amino acid
AV644_RS06655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AV644_RS06665	COG3425	synthase
AV644_RS06680	COG1272	protein, Hemolysin III
AV644_RS06725	COG0745	RESPONSE REGULATOR receiver
AV644_RS06730	COG2357	RelA SpoT domain protein
AV644_RS06735	COG1132	(ABC) transporter
AV644_RS06755	COG0242	peptide deformylase activity
AV644_RS06760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV644_RS06770	COG1132	(ABC) transporter
AV644_RS06785	COG0488	(ABC) transporter
AV644_RS06815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV644_RS06815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AV644_RS06815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AV644_RS06820	COG1105	Belongs to the carbohydrate kinase PfkB family
AV644_RS06825	COG1349	DNA-binding transcription factor activity
AV644_RS06830	COG1388	LysM domain
AV644_RS06830	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV644_RS06880	COG1837	Belongs to the UPF0109 family
AV644_RS06885	COG0228	four-way junction DNA binding
AV644_RS06890	COG0577	efflux transmembrane transporter activity
AV644_RS06895	COG1136	(ABC) transporter
AV644_RS06900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV644_RS06910	COG0505	Belongs to the CarA family
AV644_RS06920	COG0564	pseudouridine synthase activity
AV644_RS06930	COG0583	DNA-binding transcription factor activity
AV644_RS06935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AV644_RS06955	COG0301	tRNA thio-modification
AV644_RS06960	COG1104	cysteine desulfurase activity
AV644_RS06970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV644_RS06975	COG3679	Belongs to the UPF0342 family
AV644_RS06980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AV644_RS06985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV644_RS06995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AV644_RS07000	COG1368	sulfuric ester hydrolase activity
AV644_RS07005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AV644_RS07015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV644_RS07020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV644_RS07040	COG2195	Cleaves the N-terminal amino acid of tripeptides
AV644_RS07045	COG2244	polysaccharide biosynthetic process
AV644_RS07050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV644_RS07055	COG1120	ATPase activity
AV644_RS07060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV644_RS07065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV644_RS07070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV644_RS07080	COG1227	inorganic diphosphatase activity
AV644_RS07085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AV644_RS07090	COG1253	flavin adenine dinucleotide binding
AV644_RS07095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AV644_RS07100	COG1242	4 iron, 4 sulfur cluster binding
AV644_RS07105	COG0671	phosphoesterase, PA-phosphatase related
AV644_RS07110	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AV644_RS07145	COG0297	glycogen (starch) synthase activity
AV644_RS07185	COG3475	LICD family
AV644_RS07200	COG0463	Glycosyl transferase, family 2
AV644_RS07205	COG1215	transferase activity, transferring glycosyl groups
AV644_RS07215	COG1091	dTDP-4-dehydrorhamnose reductase activity
AV644_RS07220	COG2151	metal-sulfur cluster biosynthetic enzyme
AV644_RS07225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV644_RS07230	COG0358	DNA primase activity
AV644_RS07235	COG1970	mechanosensitive ion channel activity
AV644_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV644_RS07255	COG0004	ammonium transporteR
AV644_RS07265	COG1054	Belongs to the UPF0176 family
AV644_RS07275	COG2271	Major facilitator Superfamily
AV644_RS07280	COG0058	SHG alpha-glucan phosphorylase activity
AV644_RS07285	COG1640	4-alpha-glucanotransferase
AV644_RS07290	COG1609	Transcriptional regulator
AV644_RS07300	COG1175	transmembrane transport
AV644_RS07305	COG3833	ABC-type maltose transport systems, permease component
AV644_RS07310	COG3104	oligopeptide transport
AV644_RS07330	COG0438	transferase activity, transferring glycosyl groups
AV644_RS07335	COG0653	protein targeting
AV644_RS07355	COG0201	protein transport
AV644_RS07360	COG1442	glycosyl transferase family 8
AV644_RS07365	COG1442	glycosyl transferase family 8
AV644_RS07365	COG1216	Glycosyl transferase, family 2
AV644_RS07370	COG1442	glycosyl transferase family 8
AV644_RS07375	COG1442	glycosyl transferase family 8
AV644_RS07375	COG1216	Glycosyl transferase, family 2
AV644_RS07380	COG1442	glycosyl transferase family 8
AV644_RS07410	COG0765	amino acid transport
AV644_RS07415	COG1126	abc transporter atp-binding protein
AV644_RS07440	COG2309	aminopeptidase activity
AV644_RS07455	COG1187	pseudouridine synthase activity
AV644_RS07460	COG0656	L-ascorbic acid biosynthetic process
AV644_RS07465	COG0778	Nitroreductase
AV644_RS07470	COG0346	lactoylglutathione lyase activity
AV644_RS07475	COG0463	Glycosyl transferase, family 2
AV644_RS07480	COG1113	amino acid transport
AV644_RS07485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AV644_RS07490	COG0557	exoribonuclease II activity
AV644_RS07505	COG2814	Major facilitator Superfamily
AV644_RS07515	COG1131	(ABC) transporter
AV644_RS07525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AV644_RS07530	COG1396	sequence-specific DNA binding
AV644_RS07585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV644_RS07590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AV644_RS07615	COG1702	phosphate starvation-inducible protein PhoH
AV644_RS07640	COG0233	cytoplasmic translational termination
AV644_RS07655	COG0444	Belongs to the ABC transporter superfamily
AV644_RS07660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV644_RS07665	COG0601	transmembrane transport
AV644_RS07675	COG0081	regulation of translation
AV644_RS07680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV644_RS07690	COG1473	amidohydrolase
AV644_RS07695	COG0583	DNA-binding transcription factor activity
AV644_RS07710	COG1674	ftsk spoiiie
AV644_RS07715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV644_RS07740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV644_RS07770	COG0673	inositol 2-dehydrogenase activity
AV644_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
AV644_RS07830	COG1114	Component of the transport system for branched-chain amino acids
AV644_RS07835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV644_RS07835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV644_RS07855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AV644_RS07865	COG0708	Exodeoxyribonuclease III
AV644_RS07870	COG1393	Belongs to the ArsC family
AV644_RS07875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV644_RS07880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV644_RS07890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV644_RS07920	COG0470	DNA polymerase III
AV644_RS07930	COG0517	IMP dehydrogenase activity
AV644_RS07970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV644_RS07975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AV644_RS07985	COG0531	amino acid
AV644_RS07990	COG0569	domain protein
AV644_RS07995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV644_RS08005	COG1187	pseudouridine synthase activity
AV644_RS08040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AV644_RS08055	COG1827	regulation of RNA biosynthetic process
AV644_RS08070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV644_RS08075	COG1254	Belongs to the acylphosphatase family
AV644_RS08085	COG0765	amino acid transport
AV644_RS08090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV644_RS08105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV644_RS08130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AV644_RS08140	COG1484	DNA-dependent DNA replication
AV644_RS08155	COG5002	protein histidine kinase activity
AV644_RS08160	COG0745	RESPONSE REGULATOR receiver
AV644_RS08170	COG0501	Belongs to the peptidase M48B family
AV644_RS08175	COG1704	LemA family
AV644_RS08180	COG0357	Ribosomal RNA small subunit methyltransferase G
AV644_RS08185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV644_RS08190	COG0569	domain protein
AV644_RS08215	COG1114	Component of the transport system for branched-chain amino acids
AV644_RS08220	COG1063	alcohol dehydrogenase
AV644_RS08245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV644_RS08250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AV644_RS08260	COG0217	transcriptional regulatory protein
AV644_RS08265	COG2376	Dihydroxyacetone kinase
AV644_RS08270	COG1309	transcriptional regulator
AV644_RS08280	COG2376	Dihydroxyacetone kinase
AV644_RS08285	COG1461	Dihydroxyacetone kinase
AV644_RS08290	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AV644_RS08295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV644_RS08305	COG0789	Transcriptional regulator
AV644_RS08320	COG2226	methyltransferase
AV644_RS08325	COG0799	negative regulation of ribosome biogenesis
AV644_RS08335	COG1713	HD superfamily hydrolase involved in NAD metabolism
AV644_RS08340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AV644_RS08345	COG1534	Rna-binding protein
AV644_RS08350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV644_RS08355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AV644_RS08380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV644_RS08380	COG0574	Belongs to the PEP-utilizing enzyme family
AV644_RS08390	COG0517	IMP dehydrogenase activity
AV644_RS08400	COG1335	isochorismatase
AV644_RS08405	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AV644_RS08410	COG0436	Aminotransferase
AV644_RS08415	COG0589	response to stress
AV644_RS08420	COG0561	phosphatase activity
AV644_RS08425	COG0252	asparaginase activity
AV644_RS08435	COG4989	oxidoreductase activity
AV644_RS08440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV644_RS08445	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV644_RS08445	COG3942	CHAP domain
AV644_RS08455	COG0736	holo-[acyl-carrier-protein] synthase activity
AV644_RS08460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV644_RS08470	COG1482	cell wall glycoprotein biosynthetic process
AV644_RS08475	COG1940	carbohydrate kinase activity
AV644_RS08480	COG1263	PTS System
AV644_RS08480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS08480	COG2190	(PTS) system
AV644_RS08485	COG1621	beta-fructofuranosidase activity
AV644_RS08490	COG1609	Transcriptional regulator
AV644_RS08495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV644_RS08505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV644_RS08555	COG2131	deaminase
AV644_RS08570	COG2814	Major facilitator Superfamily
AV644_RS08600	COG0629	single-stranded DNA binding
AV644_RS08605	COG0360	Binds together with S18 to 16S ribosomal RNA
AV644_RS08610	COG1194	a g-specific adenine glycosylase
AV644_RS08620	COG3118	belongs to the thioredoxin family
AV644_RS08650	COG0681	Belongs to the peptidase S26 family
AV644_RS08655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AV644_RS08670	COG1882	Formate acetyltransferase
AV644_RS08680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV644_RS08695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV644_RS08705	COG2814	Major facilitator Superfamily
AV644_RS08710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV644_RS08725	COG0142	geranyltranstransferase activity
AV644_RS08730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV644_RS08735	COG4988	ABC transporter
AV644_RS08740	COG1294	oxidase, subunit
AV644_RS08745	COG1271	oxidase subunit
AV644_RS08750	COG1252	NADH dehydrogenase
AV644_RS08785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV644_RS08790	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AV644_RS08790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AV644_RS08790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AV644_RS08795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV644_RS08800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AV644_RS08805	COG3711	transcriptional antiterminator
AV644_RS08805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV644_RS08825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AV644_RS08840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AV644_RS08845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AV644_RS08850	COG0789	Transcriptional regulator
AV644_RS08865	COG2081	HI0933 family
AV644_RS08895	COG0456	acetyltransferase
AV644_RS08900	COG1214	PFAM Peptidase M22, glycoprotease
AV644_RS08915	COG3942	CHAP domain
AV644_RS08920	COG0174	glutamine synthetase
AV644_RS08925	COG0789	Transcriptional regulator
AV644_RS08940	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AV644_RS08965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV644_RS08990	COG1162	GTPase activity
AV644_RS09015	COG0084	hydrolase, TatD family'
AV644_RS09040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AV644_RS09045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV644_RS09050	COG1696	Membrane protein involved in D-alanine export
AV644_RS09070	COG0745	RESPONSE REGULATOR receiver
AV644_RS09080	COG3314	Sporulation integral membrane protein YlbJ
AV644_RS09090	COG3448	diguanylate cyclase activity
AV644_RS09090	COG4175	Glycine betaine
AV644_RS09100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AV644_RS09120	COG1070	Carbohydrate kinase
AV644_RS09130	COG3775	system Galactitol-specific IIC component
AV644_RS09135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV644_RS09145	COG1609	Transcriptional regulator
AV644_RS09230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV644_RS09235	COG1428	Deoxynucleoside kinase
AV644_RS09245	COG0542	response to heat
AV644_RS09250	COG4463	regulation of RNA biosynthetic process
AV644_RS09260	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AV644_RS09270	COG0450	alkyl hydroperoxide reductase
AV644_RS09285	COG0025	NhaP-type Na H and K H
AV644_RS09295	COG1619	proteins homologs of microcin C7 resistance protein MccF
AV644_RS09300	COG3590	peptidase
AV644_RS09375	COG0582	viral genome integration into host DNA
AV644_RS09385	COG1609	Transcriptional regulator
AV644_RS09395	COG3716	PTS system mannose fructose sorbose family IID component
AV644_RS09400	COG3715	PTS system
AV644_RS09405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS09410	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AV644_RS09420	COG1028	Short-chain dehydrogenase reductase Sdr
AV644_RS09450	COG2176	DNA-directed DNA polymerase activity
AV644_RS09455	COG1388	LysM domain
AV644_RS09455	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV644_RS09470	COG4589	Belongs to the CDS family
AV644_RS09475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV644_RS09480	COG1862	Preprotein translocase
AV644_RS09495	COG3493	citrate carrier protein
AV644_RS09500	COG3290	protein histidine kinase activity
AV644_RS09505	COG4565	transcriptional regulatory protein
AV644_RS09510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV644_RS09520	COG3842	ATPase activity
AV644_RS09590	COG1490	D-aminoacyl-tRNA deacylase activity
AV644_RS09600	COG0737	Belongs to the 5'-nucleotidase family
AV644_RS09610	COG1363	Peptidase, m42
AV644_RS09625	COG2207	Transcriptional regulator
AV644_RS09625	COG4753	response regulator
AV644_RS09630	COG2972	Histidine kinase
AV644_RS09635	COG3716	PTS system mannose fructose sorbose family IID component
AV644_RS09640	COG3715	PTS system
AV644_RS09670	COG1131	(ABC) transporter
AV644_RS09680	COG2274	protein secretion by the type I secretion system
AV644_RS09685	COG3290	protein histidine kinase activity
AV644_RS09690	COG3279	Response regulator of the LytR AlgR family
AV644_RS09705	COG1263	PTS System
AV644_RS09705	COG2190	(PTS) system
AV644_RS09705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AV644_RS09710	COG5002	protein histidine kinase activity
AV644_RS09715	COG0745	RESPONSE REGULATOR receiver
AV644_RS09725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV644_RS09730	COG0581	inorganic phosphate transmembrane transporter activity
AV644_RS09735	COG0573	inorganic phosphate transmembrane transporter activity
AV644_RS09750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV644_RS09790	COG0456	acetyltransferase
AV644_RS09795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV644_RS09850	COG1674	ftsk spoiiie
AV644_RS09860	COG2946	Replication initiation factor
AV644_RS09890	COG0741	lytic transglycosylase activity
AV644_RS09890	COG0791	NLP P60 protein
AV644_RS09995	COG1131	(ABC) transporter
AV644_RS10035	COG1131	(ABC) transporter
AV644_RS10045	COG1396	sequence-specific DNA binding
AV644_RS10055	COG1694	Mazg nucleotide pyrophosphohydrolase
AV644_RS10060	COG1611	Belongs to the LOG family
AV644_RS10070	COG2897	thiosulfate sulfurtransferase activity
AV644_RS10080	COG2814	Major facilitator Superfamily
AV644_RS10085	COG1309	transcriptional regulator
AV644_RS10095	COG0371	Dehydrogenase
AV644_RS10105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AV644_RS10105	COG0646	methionine synthase
AV644_RS10110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV644_RS10120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV644_RS10130	COG0745	RESPONSE REGULATOR receiver
AV644_RS10135	COG2205	protein histidine kinase activity
AV644_RS10135	COG2770	Histidine kinase
AV644_RS10150	COG2814	Major facilitator Superfamily
AV644_RS10155	COG4667	esterase of the alpha-beta hydrolase superfamily
AV644_RS10180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV644_RS10185	COG0564	pseudouridine synthase activity
AV644_RS10205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AV644_RS10210	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AV644_RS10230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AV644_RS10235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV644_RS10235	COG1116	anion transmembrane transporter activity
AV644_RS10245	COG0561	phosphatase activity
AV644_RS10250	COG2514	catechol 2,3-dioxygenase activity
AV644_RS10255	COG3022	response to hydroperoxide
AV644_RS10260	COG0602	queuosine metabolic process
AV644_RS10280	COG1328	CTP reductase activity
AV644_RS10280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AV644_RS10300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV644_RS10310	COG1393	Belongs to the ArsC family
AV644_RS10315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AV644_RS10320	COG1546	Belongs to the CinA family
AV644_RS10320	COG1058	Belongs to the CinA family
AV644_RS10325	COG2818	Glycosylase
AV644_RS10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV644_RS10380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV644_RS10385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV644_RS10400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AV644_RS10455	COG4974	Belongs to the 'phage' integrase family
AV644_RS10480	COG4974	Belongs to the 'phage' integrase family
AV644_RS10490	COG0745	RESPONSE REGULATOR receiver
AV644_RS10495	COG5002	protein histidine kinase activity
AV644_RS10500	COG1288	antiporter activity
AV644_RS10510	COG0517	IMP dehydrogenase activity
AV644_RS10510	COG1125	glycine betaine transport
AV644_RS10515	COG1174	glycine betaine transport
AV644_RS10520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AV644_RS10520	COG0392	lysyltransferase activity
AV644_RS10530	COG3759	membrane
AV644_RS10655	COG0582	viral genome integration into host DNA
AV644_RS10670	COG0305	Participates in initiation and elongation during chromosome replication
AV644_RS10690	COG2095	MarC family integral membrane protein
AV644_RS10695	COG0482	sulfurtransferase activity
AV644_RS10700	COG1760	l-serine dehydratase
AV644_RS10705	COG1760	l-serine dehydratase
AV644_RS10710	COG0741	lytic transglycosylase activity
AV644_RS10735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV644_RS10740	COG0612	Peptidase, M16
AV644_RS10745	COG0612	Peptidase, M16
AV644_RS10750	COG2501	S4 domain
AV644_RS10770	COG0516	GMP reductase activity
AV644_RS10770	COG0517	IMP dehydrogenase activity
AV644_RS10780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV644_RS10795	COG0454	-acetyltransferase
AV644_RS10810	COG0549	Belongs to the carbamate kinase family
AV644_RS10825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV644_RS10830	COG0488	(ABC) transporter
AV644_RS10835	COG4485	Bacterial membrane protein, YfhO
AV644_RS10855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV644_RS10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV644_RS10865	COG1475	DNA binding