locus-tag	class	description
DK41_RS00010	COG0592	DNA-directed DNA polymerase activity
DK41_RS00035	COG0012	GTP binding
DK41_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK41_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK41_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK41_RS00265	COG0436	Aminotransferase
DK41_RS00285	COG0416	fatty acid biosynthetic process
DK41_RS00290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK41_RS00295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DK41_RS00300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK41_RS00315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DK41_RS00320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK41_RS00330	COG0138	bifunctional purine biosynthesis protein purh
DK41_RS00355	COG1175	transmembrane transport
DK41_RS00360	COG0395	ABC-type sugar transport system, permease component
DK41_RS00375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK41_RS00385	COG3458	cephalosporin-C deacetylase activity
DK41_RS00400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DK41_RS00430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DK41_RS00445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK41_RS00455	COG2755	lipolytic protein G-D-S-L family
DK41_RS00455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DK41_RS00460	COG1454	alcohol dehydrogenase
DK41_RS00460	COG1012	belongs to the aldehyde dehydrogenase family
DK41_RS00465	COG1064	alcohol dehydrogenase
DK41_RS00475	COG0534	Mate efflux family protein
DK41_RS00585	COG0201	protein transport
DK41_RS00590	COG0563	adenylate kinase activity
DK41_RS00600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DK41_RS00610	COG0202	RNA polymerase activity
DK41_RS00735	COG3344	reverse transcriptase
DK41_RS00755	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK41_RS00770	COG0443	Heat shock 70 kDa protein
DK41_RS00780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK41_RS00785	COG0101	tRNA pseudouridine synthase activity
DK41_RS00790	COG0351	phosphomethylpyrimidine kinase
DK41_RS00795	COG4720	Psort location CytoplasmicMembrane, score
DK41_RS00805	COG0668	transmembrane transport
DK41_RS00835	COG0756	dUTP diphosphatase activity
DK41_RS00850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK41_RS00855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DK41_RS00860	COG1879	ABC-type sugar transport system periplasmic component
DK41_RS00865	COG1172	Belongs to the binding-protein-dependent transport system permease family
DK41_RS00880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DK41_RS00885	COG1609	Transcriptional regulator
DK41_RS00890	COG0577	efflux transmembrane transporter activity
DK41_RS00895	COG1136	(ABC) transporter
DK41_RS00900	COG0745	RESPONSE REGULATOR receiver
DK41_RS00905	COG5002	protein histidine kinase activity
DK41_RS00920	COG0191	fructose-bisphosphate aldolase activity
DK41_RS00940	COG1461	Dihydroxyacetone kinase
DK41_RS00965	COG1126	abc transporter atp-binding protein
DK41_RS00970	COG0765	amino acid transport
DK41_RS00990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK41_RS00995	COG3344	reverse transcriptase
DK41_RS01010	COG0719	Fe-S assembly protein
DK41_RS01015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DK41_RS01025	COG0719	Fe-S assembly protein
DK41_RS01030	COG1686	Belongs to the peptidase S11 family
DK41_RS01035	COG1686	Belongs to the peptidase S11 family
DK41_RS01040	COG4166	transmembrane transport
DK41_RS01045	COG0601	transmembrane transport
DK41_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK41_RS01055	COG0444	Belongs to the ABC transporter superfamily
DK41_RS01060	COG4608	Belongs to the ABC transporter superfamily
DK41_RS01100	COG1121	(ABC) transporter
DK41_RS01105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK41_RS01115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DK41_RS01120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK41_RS01120	COG4499	WXG100 protein secretion system (Wss), protein YukC
DK41_RS01140	COG3344	reverse transcriptase
DK41_RS01150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DK41_RS01155	COG1459	type II secretion system
DK41_RS01190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DK41_RS01195	COG1363	Peptidase, m42
DK41_RS01210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK41_RS01215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK41_RS01230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK41_RS01250	COG1346	cytolysis
DK41_RS01260	COG0601	transmembrane transport
DK41_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK41_RS01270	COG1122	ATPase activity
DK41_RS01280	COG1263	PTS System
DK41_RS01280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS01285	COG0366	Alpha amylase catalytic
DK41_RS01290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK41_RS01305	COG3959	Transketolase, thiamine diphosphate binding domain
DK41_RS01310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK41_RS01315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DK41_RS01335	COG1045	serine acetyltransferase
DK41_RS01345	COG0215	cysteine-tRNA ligase activity
DK41_RS01350	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK41_RS01375	COG1476	TRANSCRIPTIONal
DK41_RS01380	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK41_RS01390	COG4974	Belongs to the 'phage' integrase family
DK41_RS01495	COG1396	sequence-specific DNA binding
DK41_RS01500	COG2814	Major facilitator Superfamily
DK41_RS01510	COG1732	Glycine betaine
DK41_RS01610	COG0519	Catalyzes the synthesis of GMP from XMP
DK41_RS01655	COG1695	Transcriptional regulator
DK41_RS01670	COG1755	Isoprenylcysteine carboxyl methyltransferase
DK41_RS01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK41_RS01715	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK41_RS01735	COG1131	(ABC) transporter
DK41_RS01745	COG2190	(PTS) system
DK41_RS01745	COG1263	PTS System
DK41_RS01745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS01750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DK41_RS01755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DK41_RS01760	COG0275	rRNA processing
DK41_RS01770	COG0768	penicillin binding
DK41_RS01780	COG0513	Belongs to the DEAD box helicase family
DK41_RS01795	COG1126	abc transporter atp-binding protein
DK41_RS01805	COG0492	ferredoxin-NADP+ reductase activity
DK41_RS01810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK41_RS01825	COG3579	cysteine-type endopeptidase activity
DK41_RS01830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK41_RS01850	COG0116	Belongs to the methyltransferase superfamily
DK41_RS01860	COG1854	S-ribosylhomocysteine lyase activity
DK41_RS01865	COG4372	Transposase
DK41_RS01865	COG1418	mRNA catabolic process
DK41_RS01870	COG1131	(ABC) transporter
DK41_RS01885	COG2197	response regulator
DK41_RS01895	COG0194	GDP metabolic process
DK41_RS01905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK41_RS01910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK41_RS01915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK41_RS01915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK41_RS01925	COG0515	serine threonine protein kinase
DK41_RS01925	COG2815	serine threonine protein kinase
DK41_RS01935	COG4585	Histidine kinase
DK41_RS01940	COG2197	response regulator
DK41_RS01950	COG1098	S1 RNA binding domain
DK41_RS01955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK41_RS01960	COG1349	DNA-binding transcription factor activity
DK41_RS01970	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK41_RS01980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK41_RS01985	COG1882	Formate acetyltransferase
DK41_RS02005	COG1739	Uncharacterized protein family UPF0029
DK41_RS02010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DK41_RS02015	COG1040	competence protein
DK41_RS02050	COG0527	aspartate kinase activity
DK41_RS02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK41_RS02060	COG1024	Enoyl-CoA hydratase
DK41_RS02070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK41_RS02080	COG2070	2-Nitropropane dioxygenase
DK41_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK41_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
DK41_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK41_RS02110	COG0439	Biotin carboxylase
DK41_RS02135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DK41_RS02155	COG3716	PTS system mannose fructose sorbose family IID component
DK41_RS02160	COG3715	PTS system
DK41_RS02170	COG0561	phosphatase activity
DK41_RS02185	COG2252	PERMEase
DK41_RS02190	COG0802	atpase or kinase
DK41_RS02200	COG1316	TRANSCRIPTIONal
DK41_RS02210	COG0537	adenosine 5'-monophosphoramidase activity
DK41_RS02225	COG1131	(ABC) transporter
DK41_RS02230	COG4473	ABC transporter
DK41_RS02240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DK41_RS02255	COG0195	Participates in both transcription termination and antitermination
DK41_RS02260	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DK41_RS02270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK41_RS02275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK41_RS02300	COG2860	membrane
DK41_RS02310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK41_RS02310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK41_RS02315	COG1832	CoA-binding protein
DK41_RS02325	COG3344	reverse transcriptase
DK41_RS02340	COG5002	protein histidine kinase activity
DK41_RS02360	COG1268	BioY protein
DK41_RS02365	COG1234	tRNA 3'-trailer cleavage
DK41_RS02380	COG0166	Belongs to the GPI family
DK41_RS02385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK41_RS02390	COG0457	Tetratricopeptide repeat
DK41_RS02390	COG0705	Rhomboid family
DK41_RS02395	COG1744	ABC transporter substrate-binding protein PnrA-like
DK41_RS02405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK41_RS02420	COG0706	membrane insertase activity
DK41_RS02490	COG2137	regulation of response to DNA damage stimulus
DK41_RS02495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK41_RS02505	COG2153	protein acetylation
DK41_RS02515	COG1442	glycosyl transferase family 8
DK41_RS02515	COG1216	Glycosyl transferase, family 2
DK41_RS02550	COG2801	Transposase and inactivated derivatives
DK41_RS02560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DK41_RS02570	COG0789	Transcriptional regulator
DK41_RS02580	COG0656	L-ascorbic acid biosynthetic process
DK41_RS02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK41_RS02650	COG0673	inositol 2-dehydrogenase activity
DK41_RS02660	COG2315	Protein conserved in bacteria
DK41_RS02675	COG0742	ribosomal rna small subunit methyltransferase
DK41_RS02690	COG3480	Lon protease (S16) C-terminal proteolytic domain
DK41_RS02695	COG0737	Belongs to the 5'-nucleotidase family
DK41_RS02700	COG4470	Protein conserved in bacteria
DK41_RS02705	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DK41_RS02715	COG1132	(ABC) transporter
DK41_RS02720	COG1132	(ABC) transporter
DK41_RS02725	COG0512	Glutamine amidotransferase of anthranilate synthase
DK41_RS02730	COG1268	BioY protein
DK41_RS02735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DK41_RS02755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK41_RS02770	COG1940	carbohydrate kinase activity
DK41_RS02775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DK41_RS02780	COG1217	gtp-binding protein TYPA
DK41_RS02790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DK41_RS02815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DK41_RS02825	COG0762	integral membrane protein
DK41_RS02830	COG2302	S4 RNA-binding domain
DK41_RS02835	COG3599	regulation of cell shape
DK41_RS02840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DK41_RS02850	COG0494	nUDIX hydrolase
DK41_RS02855	COG0542	response to heat
DK41_RS02860	COG4703	Protein of unknown function (DUF1797)
DK41_RS02865	COG0765	amino acid transport
DK41_RS02870	COG1126	abc transporter atp-binding protein
DK41_RS02875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK41_RS02885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK41_RS02890	COG1570	exodeoxyribonuclease VII activity
DK41_RS02895	COG1722	exodeoxyribonuclease VII activity
DK41_RS02905	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK41_RS02910	COG1438	arginine binding
DK41_RS02915	COG0497	DNA recombination
DK41_RS02920	COG1307	EDD domain protein, DegV family
DK41_RS02925	COG2755	lipolytic protein G-D-S-L family
DK41_RS02945	COG2801	Transposase and inactivated derivatives
DK41_RS02980	COG1078	dGTPase activity
DK41_RS03005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DK41_RS03015	COG2884	Cell division ATP-binding protein ftsE
DK41_RS03020	COG2177	Part of the ABC transporter FtsEX involved in
DK41_RS03040	COG3344	reverse transcriptase
DK41_RS03045	COG1199	ATP-dependent helicase activity
DK41_RS03045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DK41_RS03050	COG0436	Aminotransferase
DK41_RS03055	COG0017	Asparaginyl-tRNA synthetase
DK41_RS03075	COG1660	Displays ATPase and GTPase activities
DK41_RS03105	COG0254	rRNA binding
DK41_RS03110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DK41_RS03115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DK41_RS03120	COG0716	FMN binding
DK41_RS03125	COG1605	Chorismate mutase
DK41_RS03125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DK41_RS03130	COG0038	chloride channel
DK41_RS03135	COG0335	large ribosomal subunit rRNA binding
DK41_RS03170	COG1136	(ABC) transporter
DK41_RS03185	COG5002	protein histidine kinase activity
DK41_RS03210	COG0772	Belongs to the SEDS family
DK41_RS03215	COG5433	transposase activity
DK41_RS03235	COG0560	Phosphoserine phosphatase
DK41_RS03250	COG0148	phosphopyruvate hydratase activity
DK41_RS03270	COG1316	TRANSCRIPTIONal
DK41_RS03285	COG1192	Involved in chromosome partitioning
DK41_RS03290	COG1475	DNA binding
DK41_RS03405	COG4509	Sortase family
DK41_RS03410	COG0791	NLP P60 protein
DK41_RS03410	COG0741	lytic transglycosylase activity
DK41_RS03435	COG1876	peptidase activity
DK41_RS03440	COG2720	vancomycin resistance protein
DK41_RS03445	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK41_RS03475	COG2337	Toxic component of a toxin-antitoxin (TA) module
DK41_RS03480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK41_RS03550	COG0551	DNA topoisomerase type I activity
DK41_RS03550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK41_RS03585	COG4581	dead DEAH box helicase
DK41_RS03600	COG1309	transcriptional regulator
DK41_RS03605	COG1132	(ABC) transporter
DK41_RS03605	COG2375	cellular response to nickel ion
DK41_RS03610	COG1132	(ABC) transporter
DK41_RS03625	COG1129	ABC transporter
DK41_RS03630	COG0534	Mate efflux family protein
DK41_RS03665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK41_RS03670	COG4555	ABC transporter
DK41_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
DK41_RS03700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK41_RS03705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DK41_RS03725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DK41_RS03730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK41_RS03760	COG1136	(ABC) transporter
DK41_RS03775	COG0586	Pfam SNARE associated Golgi protein
DK41_RS03780	COG4619	ABC transporter
DK41_RS03785	COG0390	transport system, permease component
DK41_RS03795	COG0583	DNA-binding transcription factor activity
DK41_RS03810	COG2211	Major facilitator Superfamily
DK41_RS03820	COG3250	beta-galactosidase activity
DK41_RS03825	COG2186	Transcriptional regulator
DK41_RS03830	COG0800	Aldolase
DK41_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
DK41_RS03860	COG3344	reverse transcriptase
DK41_RS03875	COG1609	Transcriptional regulator
DK41_RS03890	COG0438	transferase activity, transferring glycosyl groups
DK41_RS03915	COG0765	amino acid transport
DK41_RS03920	COG0765	amino acid transport
DK41_RS03925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK41_RS03930	COG1126	abc transporter atp-binding protein
DK41_RS03935	COG0745	RESPONSE REGULATOR receiver
DK41_RS03940	COG5002	protein histidine kinase activity
DK41_RS03945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK41_RS03950	COG2832	Protein of unknown function (DUF454)
DK41_RS03960	COG1196	nuclear chromosome segregation
DK41_RS03965	COG5433	transposase activity
DK41_RS03970	COG0561	phosphatase activity
DK41_RS03975	COG0561	phosphatase activity
DK41_RS03980	COG0552	protein localization to endoplasmic reticulum
DK41_RS03990	COG3344	reverse transcriptase
DK41_RS03995	COG3689	TIGRFAM TIGR03943 family protein
DK41_RS04000	COG0701	Predicted permease
DK41_RS04015	COG2183	response to ionizing radiation
DK41_RS04020	COG3091	SprT-like family
DK41_RS04025	COG1983	PspC domain protein
DK41_RS04060	COG0826	peptidase U32
DK41_RS04065	COG4443	Transcriptional Coactivator p15 (PC4)
DK41_RS04075	COG1914	H( )-stimulated, divalent metal cation uptake system
DK41_RS04090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DK41_RS04090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DK41_RS04115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK41_RS04125	COG3344	reverse transcriptase
DK41_RS04150	COG1164	Oligoendopeptidase f
DK41_RS04160	COG0772	Belongs to the SEDS family
DK41_RS04180	COG0768	penicillin binding
DK41_RS04195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK41_RS04200	COG2223	nitrite transmembrane transporter activity
DK41_RS04225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DK41_RS04230	COG2011	ABC-type metal ion transport system permease component
DK41_RS04235	COG1464	Belongs to the NlpA lipoprotein family
DK41_RS04240	COG0513	Belongs to the DEAD box helicase family
DK41_RS04250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DK41_RS04255	COG0204	Acyl-transferase
DK41_RS04260	COG1596	polysaccharide export
DK41_RS04260	COG1555	photosystem II stabilization
DK41_RS04265	COG0658	competence protein
DK41_RS04265	COG2333	competence protein COMEC
DK41_RS04270	COG0561	phosphatase activity
DK41_RS04275	COG1609	Transcriptional regulator
DK41_RS04280	COG0657	acetylesterase activity
DK41_RS04295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DK41_RS04300	COG3711	transcriptional antiterminator
DK41_RS04305	COG2190	(PTS) system
DK41_RS04305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS04305	COG1263	PTS System
DK41_RS04315	COG3835	regulator
DK41_RS04320	COG1929	Belongs to the glycerate kinase type-1 family
DK41_RS04335	COG1846	Transcriptional regulator
DK41_RS04340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK41_RS04350	COG0363	glucosamine-6-phosphate deaminase activity
DK41_RS04355	COG0435	Glutathione S-transferase
DK41_RS04360	COG1187	pseudouridine synthase activity
DK41_RS04380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DK41_RS04385	COG4122	O-methyltransferase activity
DK41_RS04395	COG4894	glucomannan catabolic process
DK41_RS04405	COG1811	Na channel or pump
DK41_RS04410	COG1442	glycosyl transferase family 8
DK41_RS04420	COG1476	TRANSCRIPTIONal
DK41_RS04435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK41_RS04440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK41_RS04445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK41_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
DK41_RS04465	COG0726	polysaccharide deacetylase
DK41_RS04475	COG0513	Belongs to the DEAD box helicase family
DK41_RS04485	COG5433	transposase activity
DK41_RS04490	COG1956	GAF domain-containing protein
DK41_RS04495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK41_RS04505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DK41_RS04505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DK41_RS04510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK41_RS04535	COG4721	ABC-type cobalt transport system, permease component
DK41_RS04540	COG1122	ATPase activity
DK41_RS04550	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DK41_RS04560	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DK41_RS04570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK41_RS04580	COG4109	DRTGG domain
DK41_RS04585	COG0024	Methionine aminopeptidase
DK41_RS04595	COG2246	polysaccharide biosynthetic process
DK41_RS04600	COG4708	membrane
DK41_RS04605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DK41_RS04610	COG1597	lipid kinase activity
DK41_RS04615	COG1523	belongs to the glycosyl hydrolase 13 family
DK41_RS04625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK41_RS04630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK41_RS04685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK41_RS04710	COG0072	phenylalanine-tRNA ligase activity
DK41_RS04710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK41_RS04715	COG3344	reverse transcriptase
DK41_RS04725	COG2321	neutral zinc metallopeptidase
DK41_RS04730	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK41_RS04735	COG1074	ATP-dependent DNA helicase activity
DK41_RS04745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DK41_RS04750	COG0488	(ABC) transporter
DK41_RS04755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DK41_RS04760	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK41_RS04760	COG0022	dehydrogenase e1 component
DK41_RS04765	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK41_RS04775	COG0095	Lipoate-protein ligase
DK41_RS04780	COG3344	reverse transcriptase
DK41_RS04785	COG3442	glutamine amidotransferase
DK41_RS04790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK41_RS04795	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DK41_RS04820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK41_RS04830	COG0647	UMP catabolic process
DK41_RS04840	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DK41_RS04845	COG1518	maintenance of DNA repeat elements
DK41_RS04850	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DK41_RS04865	COG0481	GTPase activity
DK41_RS04875	COG1418	mRNA catabolic process
DK41_RS04880	COG0456	acetyltransferase
DK41_RS04890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK41_RS04925	COG1131	(ABC) transporter
DK41_RS04930	COG1725	Transcriptional regulator
DK41_RS04940	COG0205	6-phosphofructokinase activity
DK41_RS04945	COG0469	pyruvate kinase activity
DK41_RS04955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DK41_RS04960	COG2824	Alkylphosphonate utilization operon protein PhnA
DK41_RS04965	COG0765	amino acid transport
DK41_RS04970	COG1126	abc transporter atp-binding protein
DK41_RS04985	COG1072	(Pantothenic acid kinase))
DK41_RS04990	COG2813	Specifically methylates the guanine in position
DK41_RS05000	COG1744	ABC transporter substrate-binding protein PnrA-like
DK41_RS05005	COG3845	ABC transporter
DK41_RS05010	COG4603	Belongs to the binding-protein-dependent transport system permease family
DK41_RS05015	COG1079	Belongs to the binding-protein-dependent transport system permease family
DK41_RS05035	COG3764	Sortase (surface protein transpeptidase)
DK41_RS05040	COG0346	lactoylglutathione lyase activity
DK41_RS05045	COG3344	reverse transcriptase
DK41_RS05070	COG2188	Transcriptional regulator
DK41_RS05075	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DK41_RS05085	COG1464	Belongs to the NlpA lipoprotein family
DK41_RS05100	COG1136	(ABC) transporter
DK41_RS05110	COG0745	RESPONSE REGULATOR receiver
DK41_RS05115	COG5002	protein histidine kinase activity
DK41_RS05120	COG4974	Belongs to the 'phage' integrase family
DK41_RS05125	COG4166	transmembrane transport
DK41_RS05140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK41_RS05145	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DK41_RS05150	COG5002	protein histidine kinase activity
DK41_RS05155	COG0745	RESPONSE REGULATOR receiver
DK41_RS05165	COG0704	Plays a role in the regulation of phosphate uptake
DK41_RS05170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK41_RS05175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK41_RS05180	COG0581	inorganic phosphate transmembrane transporter activity
DK41_RS05185	COG0573	inorganic phosphate transmembrane transporter activity
DK41_RS05195	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DK41_RS05195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK41_RS05200	COG0483	inositol monophosphate 1-phosphatase activity
DK41_RS05205	COG4476	Belongs to the UPF0223 family
DK41_RS05215	COG0196	riboflavin kinase activity
DK41_RS05220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK41_RS05250	COG1136	(ABC) transporter
DK41_RS05255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK41_RS05260	COG0758	DNA mediated transformation
DK41_RS05265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DK41_RS05270	COG4604	ABC transporter, ATP-binding protein
DK41_RS05275	COG4605	iron ion homeostasis
DK41_RS05280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK41_RS05285	COG0110	maltose O-acetyltransferase activity
DK41_RS05295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK41_RS05300	COG1376	ErfK ybiS ycfS ynhG family protein
DK41_RS05305	COG1966	Carbon starvation protein
DK41_RS05310	COG3279	Response regulator of the LytR AlgR family
DK41_RS05315	COG3275	phosphorelay sensor kinase activity
DK41_RS05420	COG3344	reverse transcriptase
DK41_RS05450	COG0505	Belongs to the CarA family
DK41_RS05460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DK41_RS05465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DK41_RS05470	COG0284	orotidine-5'-phosphate decarboxylase activity
DK41_RS05480	COG0488	(ABC) transporter
DK41_RS05490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DK41_RS05500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK41_RS05505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DK41_RS05540	COG0095	Lipoate-protein ligase
DK41_RS05550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK41_RS05555	COG4684	Psort location CytoplasmicMembrane, score
DK41_RS05560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK41_RS05570	COG2801	Transposase and inactivated derivatives
DK41_RS05580	COG1132	(ABC) transporter
DK41_RS05600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DK41_RS05610	COG2890	protein-(glutamine-N5) methyltransferase activity
DK41_RS05615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK41_RS05625	COG1942	4-Oxalocrotonate Tautomerase
DK41_RS05640	COG1053	succinate dehydrogenase
DK41_RS05640	COG3976	FMN-binding domain protein
DK41_RS05640	COG0431	NADPH-dependent FMN reductase
DK41_RS05650	COG2233	PERMEase
DK41_RS05660	COG0516	GMP reductase activity
DK41_RS05665	COG0477	Major facilitator Superfamily
DK41_RS05680	COG4221	oxidoreductase activity
DK41_RS05685	COG0280	phosphate acetyltransferase
DK41_RS05690	COG0564	pseudouridine synthase activity
DK41_RS05695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DK41_RS05700	COG2357	RelA SpoT domain protein
DK41_RS05715	COG1104	cysteine desulfurase activity
DK41_RS05735	COG0628	permease
DK41_RS05750	COG0561	phosphatase activity
DK41_RS05760	COG0038	chloride channel
DK41_RS05770	COG1177	transmembrane transport
DK41_RS05775	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK41_RS05785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK41_RS05790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DK41_RS05810	COG0285	dihydrofolate synthase activity
DK41_RS05815	COG2962	Rard protein
DK41_RS05830	COG0726	polysaccharide deacetylase
DK41_RS05840	COG3344	reverse transcriptase
DK41_RS05845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DK41_RS05850	COG1012	belongs to the aldehyde dehydrogenase family
DK41_RS05925	COG2261	transglycosylase associated protein
DK41_RS05935	COG3344	reverse transcriptase
DK41_RS05960	COG1115	amino acid carrier protein
DK41_RS05965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DK41_RS05975	COG1346	cytolysis
DK41_RS06010	COG4974	Belongs to the 'phage' integrase family
DK41_RS06025	COG0539	negative regulation of cytoplasmic translation
DK41_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DK41_RS06055	COG0187	DNA topoisomerase II activity
DK41_RS06060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DK41_RS06065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK41_RS06075	COG1083	cytidylyl-transferase
DK41_RS06075	COG2755	lipolytic protein G-D-S-L family
DK41_RS06090	COG2089	acid synthase
DK41_RS06115	COG1216	Glycosyl transferase, family 2
DK41_RS06115	COG1442	glycosyl transferase family 8
DK41_RS06120	COG1442	glycosyl transferase family 8
DK41_RS06120	COG1216	Glycosyl transferase, family 2
DK41_RS06135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DK41_RS06160	COG1316	TRANSCRIPTIONal
DK41_RS06185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK41_RS06200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK41_RS06220	COG3842	ATPase activity
DK41_RS06235	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DK41_RS06240	COG3527	Alpha-acetolactate decarboxylase
DK41_RS06245	COG0028	Belongs to the TPP enzyme family
DK41_RS06250	COG0457	Tetratricopeptide repeat
DK41_RS06255	COG0628	permease
DK41_RS06265	COG1051	belongs to the nudix hydrolase family
DK41_RS06270	COG5492	domain, Protein
DK41_RS06275	COG1088	dTDP-glucose 4,6-dehydratase activity
DK41_RS06285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DK41_RS06290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK41_RS06300	COG2384	SAM-dependent methyltransferase
DK41_RS06320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DK41_RS06320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DK41_RS06325	COG0300	oxidoreductase activity
DK41_RS06340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK41_RS06380	COG1573	uracil-dna glycosylase
DK41_RS06385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK41_RS06395	COG0584	glycerophosphoryl diester phosphodiesterase
DK41_RS06400	COG0322	excinuclease ABC activity
DK41_RS06410	COG0534	Mate efflux family protein
DK41_RS06445	COG2801	Transposase and inactivated derivatives
DK41_RS06465	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK41_RS06470	COG5433	transposase activity
DK41_RS06495	COG2176	DNA-directed DNA polymerase activity
DK41_RS06505	COG4974	Belongs to the 'phage' integrase family
DK41_RS06535	COG1674	ftsk spoiiie
DK41_RS06575	COG2040	homocysteine
DK41_RS06615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK41_RS06625	COG3425	synthase
DK41_RS06640	COG1272	protein, Hemolysin III
DK41_RS06685	COG0745	RESPONSE REGULATOR receiver
DK41_RS06690	COG2357	RelA SpoT domain protein
DK41_RS06695	COG1132	(ABC) transporter
DK41_RS06710	COG0737	Belongs to the 5'-nucleotidase family
DK41_RS06715	COG0242	peptide deformylase activity
DK41_RS06720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DK41_RS06730	COG1132	(ABC) transporter
DK41_RS06745	COG0488	(ABC) transporter
DK41_RS06765	COG5433	transposase activity
DK41_RS06780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK41_RS06780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK41_RS06780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK41_RS06785	COG1105	Belongs to the carbohydrate kinase PfkB family
DK41_RS06790	COG1349	DNA-binding transcription factor activity
DK41_RS06845	COG1837	Belongs to the UPF0109 family
DK41_RS06850	COG0228	four-way junction DNA binding
DK41_RS06855	COG0577	efflux transmembrane transporter activity
DK41_RS06860	COG1136	(ABC) transporter
DK41_RS06865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK41_RS06875	COG0505	Belongs to the CarA family
DK41_RS06885	COG0564	pseudouridine synthase activity
DK41_RS06895	COG0583	DNA-binding transcription factor activity
DK41_RS06900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DK41_RS06920	COG0301	tRNA thio-modification
DK41_RS06925	COG1104	cysteine desulfurase activity
DK41_RS06935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK41_RS06940	COG3679	Belongs to the UPF0342 family
DK41_RS06945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DK41_RS06960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK41_RS06965	COG1368	sulfuric ester hydrolase activity
DK41_RS06970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DK41_RS06980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DK41_RS06985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DK41_RS07010	COG2244	polysaccharide biosynthetic process
DK41_RS07015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DK41_RS07020	COG1120	ATPase activity
DK41_RS07025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK41_RS07030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK41_RS07035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK41_RS07050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK41_RS07055	COG1253	flavin adenine dinucleotide binding
DK41_RS07060	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DK41_RS07065	COG1242	4 iron, 4 sulfur cluster binding
DK41_RS07070	COG0671	phosphoesterase, PA-phosphatase related
DK41_RS07075	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DK41_RS07110	COG0297	glycogen (starch) synthase activity
DK41_RS07150	COG3475	LICD family
DK41_RS07165	COG0463	Glycosyl transferase, family 2
DK41_RS07170	COG1215	transferase activity, transferring glycosyl groups
DK41_RS07180	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK41_RS07185	COG2151	metal-sulfur cluster biosynthetic enzyme
DK41_RS07190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK41_RS07195	COG0358	DNA primase activity
DK41_RS07200	COG1970	mechanosensitive ion channel activity
DK41_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK41_RS07230	COG1054	Belongs to the UPF0176 family
DK41_RS07240	COG2271	Major facilitator Superfamily
DK41_RS07250	COG0058	SHG alpha-glucan phosphorylase activity
DK41_RS07255	COG1640	4-alpha-glucanotransferase
DK41_RS07260	COG1609	Transcriptional regulator
DK41_RS07270	COG1175	transmembrane transport
DK41_RS07275	COG3833	ABC-type maltose transport systems, permease component
DK41_RS07280	COG3104	oligopeptide transport
DK41_RS07300	COG0438	transferase activity, transferring glycosyl groups
DK41_RS07325	COG0201	protein transport
DK41_RS07330	COG1442	glycosyl transferase family 8
DK41_RS07335	COG1442	glycosyl transferase family 8
DK41_RS07335	COG1216	Glycosyl transferase, family 2
DK41_RS07340	COG1442	glycosyl transferase family 8
DK41_RS07345	COG1442	glycosyl transferase family 8
DK41_RS07345	COG1216	Glycosyl transferase, family 2
DK41_RS07350	COG1442	glycosyl transferase family 8
DK41_RS07380	COG0765	amino acid transport
DK41_RS07385	COG1126	abc transporter atp-binding protein
DK41_RS07410	COG2309	aminopeptidase activity
DK41_RS07420	COG0154	amidase activity
DK41_RS07425	COG1187	pseudouridine synthase activity
DK41_RS07430	COG0656	L-ascorbic acid biosynthetic process
DK41_RS07435	COG0778	Nitroreductase
DK41_RS07440	COG0346	lactoylglutathione lyase activity
DK41_RS07445	COG0463	Glycosyl transferase, family 2
DK41_RS07450	COG1113	amino acid transport
DK41_RS07455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DK41_RS07460	COG0557	exoribonuclease II activity
DK41_RS07470	COG2814	Major facilitator Superfamily
DK41_RS07480	COG1131	(ABC) transporter
DK41_RS07490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK41_RS07495	COG1396	sequence-specific DNA binding
DK41_RS07535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DK41_RS07540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DK41_RS07560	COG1702	phosphate starvation-inducible protein PhoH
DK41_RS07585	COG0233	cytoplasmic translational termination
DK41_RS07600	COG0444	Belongs to the ABC transporter superfamily
DK41_RS07605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK41_RS07615	COG0747	negative chemotaxis
DK41_RS07620	COG0081	regulation of translation
DK41_RS07640	COG1473	amidohydrolase
DK41_RS07645	COG0583	DNA-binding transcription factor activity
DK41_RS07655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DK41_RS07660	COG1674	ftsk spoiiie
DK41_RS07665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DK41_RS07690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DK41_RS07725	COG0673	inositol 2-dehydrogenase activity
DK41_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
DK41_RS07790	COG3344	reverse transcriptase
DK41_RS07795	COG1114	Component of the transport system for branched-chain amino acids
DK41_RS07800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK41_RS07800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK41_RS07820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK41_RS07830	COG0708	Exodeoxyribonuclease III
DK41_RS07840	COG1393	Belongs to the ArsC family
DK41_RS07845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DK41_RS07850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DK41_RS07860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DK41_RS07870	COG3344	reverse transcriptase
DK41_RS07890	COG0470	DNA polymerase III
DK41_RS07900	COG0517	IMP dehydrogenase activity
DK41_RS07940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DK41_RS07945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DK41_RS07955	COG0531	amino acid
DK41_RS07960	COG0569	domain protein
DK41_RS07975	COG1187	pseudouridine synthase activity
DK41_RS07985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DK41_RS07990	COG0582	viral genome integration into host DNA
DK41_RS08010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DK41_RS08025	COG1827	regulation of RNA biosynthetic process
DK41_RS08040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK41_RS08045	COG1254	Belongs to the acylphosphatase family
DK41_RS08050	COG0706	membrane insertase activity
DK41_RS08060	COG0765	amino acid transport
DK41_RS08065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK41_RS08080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK41_RS08090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DK41_RS08110	COG1484	DNA-dependent DNA replication
DK41_RS08125	COG5002	protein histidine kinase activity
DK41_RS08130	COG0745	RESPONSE REGULATOR receiver
DK41_RS08140	COG0501	Belongs to the peptidase M48B family
DK41_RS08145	COG1704	LemA family
DK41_RS08150	COG0357	Ribosomal RNA small subunit methyltransferase G
DK41_RS08155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK41_RS08160	COG0569	domain protein
DK41_RS08170	COG1122	ATPase activity
DK41_RS08180	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DK41_RS08185	COG1114	Component of the transport system for branched-chain amino acids
DK41_RS08190	COG1063	alcohol dehydrogenase
DK41_RS08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK41_RS08225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK41_RS08230	COG0217	transcriptional regulatory protein
DK41_RS08235	COG2376	Dihydroxyacetone kinase
DK41_RS08240	COG1309	transcriptional regulator
DK41_RS08245	COG2376	Dihydroxyacetone kinase
DK41_RS08250	COG1461	Dihydroxyacetone kinase
DK41_RS08255	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DK41_RS08260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK41_RS08270	COG0789	Transcriptional regulator
DK41_RS08275	COG1323	Belongs to the UPF0348 family
DK41_RS08285	COG2226	methyltransferase
DK41_RS08290	COG0799	negative regulation of ribosome biogenesis
DK41_RS08300	COG1713	HD superfamily hydrolase involved in NAD metabolism
DK41_RS08305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK41_RS08310	COG1534	Rna-binding protein
DK41_RS08315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK41_RS08320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DK41_RS08330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK41_RS08335	COG0154	amidase activity
DK41_RS08340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK41_RS08345	COG0574	Belongs to the PEP-utilizing enzyme family
DK41_RS08345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK41_RS08350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DK41_RS08355	COG0517	IMP dehydrogenase activity
DK41_RS08365	COG1335	isochorismatase
DK41_RS08370	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DK41_RS08375	COG0436	Aminotransferase
DK41_RS08380	COG0589	response to stress
DK41_RS08385	COG0561	phosphatase activity
DK41_RS08390	COG0252	asparaginase activity
DK41_RS08400	COG4989	oxidoreductase activity
DK41_RS08405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK41_RS08410	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK41_RS08410	COG3942	CHAP domain
DK41_RS08420	COG0736	holo-[acyl-carrier-protein] synthase activity
DK41_RS08425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK41_RS08435	COG5433	transposase activity
DK41_RS08440	COG1482	cell wall glycoprotein biosynthetic process
DK41_RS08445	COG1940	carbohydrate kinase activity
DK41_RS08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS08450	COG1263	PTS System
DK41_RS08450	COG2190	(PTS) system
DK41_RS08455	COG1621	beta-fructofuranosidase activity
DK41_RS08460	COG1609	Transcriptional regulator
DK41_RS08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK41_RS08475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DK41_RS08480	COG1132	(ABC) transporter
DK41_RS08485	COG1132	(ABC) transporter
DK41_RS08515	COG1021	2,3-dihydroxybenzoate-AMP ligase
DK41_RS08525	COG2131	deaminase
DK41_RS08530	COG0006	proline dipeptidase activity
DK41_RS08540	COG2814	Major facilitator Superfamily
DK41_RS08565	COG3344	reverse transcriptase
DK41_RS08570	COG0629	single-stranded DNA binding
DK41_RS08575	COG0360	Binds together with S18 to 16S ribosomal RNA
DK41_RS08580	COG1194	a g-specific adenine glycosylase
DK41_RS08590	COG3118	belongs to the thioredoxin family
DK41_RS08600	COG1193	negative regulation of DNA recombination
DK41_RS08615	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK41_RS08620	COG0681	Belongs to the peptidase S26 family
DK41_RS08625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK41_RS08640	COG3344	reverse transcriptase
DK41_RS08650	COG1882	Formate acetyltransferase
DK41_RS08655	COG3576	pyridoxamine 5-phosphate
DK41_RS08660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK41_RS08675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK41_RS08685	COG2814	Major facilitator Superfamily
DK41_RS08690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK41_RS08695	COG2936	dipeptidyl-peptidase activity
DK41_RS08705	COG0142	geranyltranstransferase activity
DK41_RS08710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DK41_RS08715	COG4988	ABC transporter
DK41_RS08720	COG1294	oxidase, subunit
DK41_RS08725	COG1271	oxidase subunit
DK41_RS08730	COG1252	NADH dehydrogenase
DK41_RS08765	COG3969	phosphoadenosine phosphosulfate
DK41_RS08770	COG1475	DNA binding
DK41_RS09080	COG0582	viral genome integration into host DNA
DK41_RS09085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DK41_RS09090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DK41_RS09095	COG0789	Transcriptional regulator
DK41_RS09110	COG2081	HI0933 family
DK41_RS09130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DK41_RS09135	COG0456	acetyltransferase
DK41_RS09140	COG1214	PFAM Peptidase M22, glycoprotease
DK41_RS09155	COG3942	CHAP domain
DK41_RS09160	COG0174	glutamine synthetase
DK41_RS09165	COG0789	Transcriptional regulator
DK41_RS09180	COG0126	phosphoglycerate kinase activity
DK41_RS09185	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DK41_RS09195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DK41_RS09210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK41_RS09235	COG1162	GTPase activity
DK41_RS09245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DK41_RS09260	COG0084	hydrolase, TatD family'
DK41_RS09285	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DK41_RS09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK41_RS09295	COG1696	Membrane protein involved in D-alanine export
DK41_RS09310	COG5002	protein histidine kinase activity
DK41_RS09315	COG0745	RESPONSE REGULATOR receiver
DK41_RS09320	COG5433	transposase activity
DK41_RS09330	COG3314	Sporulation integral membrane protein YlbJ
DK41_RS09395	COG0741	lytic transglycosylase activity
DK41_RS09395	COG0791	NLP P60 protein
DK41_RS09425	COG2946	Replication initiation factor
DK41_RS09430	COG1674	ftsk spoiiie
DK41_RS09450	COG4175	Glycine betaine
DK41_RS09450	COG3448	diguanylate cyclase activity
DK41_RS09455	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DK41_RS09475	COG1070	Carbohydrate kinase
DK41_RS09485	COG3775	system Galactitol-specific IIC component
DK41_RS09490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DK41_RS09500	COG1609	Transcriptional regulator
DK41_RS09555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DK41_RS09585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DK41_RS09590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK41_RS09595	COG1428	Deoxynucleoside kinase
DK41_RS09605	COG0542	response to heat
DK41_RS09610	COG4463	regulation of RNA biosynthetic process
DK41_RS09620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DK41_RS09630	COG0450	alkyl hydroperoxide reductase
DK41_RS09660	COG3177	Filamentation induced by cAMP protein fic
DK41_RS09690	COG2946	Replication initiation factor
DK41_RS09700	COG4974	Belongs to the 'phage' integrase family
DK41_RS09715	COG1619	proteins homologs of microcin C7 resistance protein MccF
DK41_RS09720	COG3590	peptidase
DK41_RS09745	COG1609	Transcriptional regulator
DK41_RS09755	COG3716	PTS system mannose fructose sorbose family IID component
DK41_RS09760	COG3715	PTS system
DK41_RS09765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS09770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DK41_RS09780	COG1028	Short-chain dehydrogenase reductase Sdr
DK41_RS09815	COG2176	DNA-directed DNA polymerase activity
DK41_RS09820	COG1388	LysM domain
DK41_RS09820	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK41_RS09835	COG4589	Belongs to the CDS family
DK41_RS09840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK41_RS09845	COG1862	Preprotein translocase
DK41_RS09860	COG3493	citrate carrier protein
DK41_RS09865	COG3290	protein histidine kinase activity
DK41_RS09870	COG4565	transcriptional regulatory protein
DK41_RS09875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK41_RS09885	COG3842	ATPase activity
DK41_RS09960	COG2801	Transposase and inactivated derivatives
DK41_RS09965	COG1490	D-aminoacyl-tRNA deacylase activity
DK41_RS09975	COG0737	Belongs to the 5'-nucleotidase family
DK41_RS09985	COG1363	Peptidase, m42
DK41_RS10005	COG4753	response regulator
DK41_RS10005	COG2207	Transcriptional regulator
DK41_RS10010	COG2972	Histidine kinase
DK41_RS10015	COG3716	PTS system mannose fructose sorbose family IID component
DK41_RS10020	COG3715	PTS system
DK41_RS10045	COG1131	(ABC) transporter
DK41_RS10055	COG3279	Response regulator of the LytR AlgR family
DK41_RS10065	COG2190	(PTS) system
DK41_RS10065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK41_RS10065	COG1263	PTS System
DK41_RS10070	COG5002	protein histidine kinase activity
DK41_RS10075	COG0745	RESPONSE REGULATOR receiver
DK41_RS10085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK41_RS10090	COG0581	inorganic phosphate transmembrane transporter activity
DK41_RS10095	COG0573	inorganic phosphate transmembrane transporter activity
DK41_RS10110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK41_RS10145	COG0456	acetyltransferase
DK41_RS10150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK41_RS10220	COG1131	(ABC) transporter
DK41_RS10230	COG1396	sequence-specific DNA binding
DK41_RS10245	COG1694	Mazg nucleotide pyrophosphohydrolase
DK41_RS10260	COG2897	thiosulfate sulfurtransferase activity
DK41_RS10275	COG0371	Dehydrogenase
DK41_RS10285	COG2801	Transposase and inactivated derivatives
DK41_RS10295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK41_RS10295	COG0646	methionine synthase
DK41_RS10310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DK41_RS10320	COG0745	RESPONSE REGULATOR receiver
DK41_RS10325	COG2770	Histidine kinase
DK41_RS10325	COG2205	protein histidine kinase activity
DK41_RS10345	COG5433	transposase activity
DK41_RS10350	COG2814	Major facilitator Superfamily
DK41_RS10355	COG4667	esterase of the alpha-beta hydrolase superfamily
DK41_RS10375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK41_RS10380	COG0564	pseudouridine synthase activity
DK41_RS10400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DK41_RS10405	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DK41_RS10425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DK41_RS10430	COG1116	anion transmembrane transporter activity
DK41_RS10430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DK41_RS10435	COG4120	Belongs to the binding-protein-dependent transport system permease family
DK41_RS10445	COG0561	phosphatase activity
DK41_RS10450	COG2514	catechol 2,3-dioxygenase activity
DK41_RS10455	COG3022	response to hydroperoxide
DK41_RS10460	COG0602	queuosine metabolic process
DK41_RS10480	COG1328	CTP reductase activity
DK41_RS10480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK41_RS10500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK41_RS10510	COG1393	Belongs to the ArsC family
DK41_RS10515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DK41_RS10520	COG1058	Belongs to the CinA family
DK41_RS10520	COG1546	Belongs to the CinA family
DK41_RS10525	COG2818	Glycosylase
DK41_RS10560	COG0018	arginyl-trna synthetase
DK41_RS10570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK41_RS10575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK41_RS10595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK41_RS10605	COG4974	Belongs to the 'phage' integrase family
DK41_RS10615	COG2946	Replication initiation factor
DK41_RS10645	COG3177	Filamentation induced by cAMP protein fic
DK41_RS10670	COG2801	Transposase and inactivated derivatives
DK41_RS10710	COG4974	Belongs to the 'phage' integrase family
DK41_RS10720	COG0745	RESPONSE REGULATOR receiver
DK41_RS10725	COG5002	protein histidine kinase activity
DK41_RS10730	COG3344	reverse transcriptase
DK41_RS10735	COG1288	antiporter activity
DK41_RS10745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK41_RS10750	COG3852	Histidine kinase
DK41_RS10755	COG0784	Response regulator, receiver
DK41_RS10760	COG1125	glycine betaine transport
DK41_RS10760	COG0517	IMP dehydrogenase activity
DK41_RS10765	COG1174	glycine betaine transport
DK41_RS10770	COG0392	lysyltransferase activity
DK41_RS10770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DK41_RS10780	COG3759	membrane
DK41_RS10900	COG0582	viral genome integration into host DNA
DK41_RS10915	COG0305	Participates in initiation and elongation during chromosome replication
DK41_RS10935	COG2095	MarC family integral membrane protein
DK41_RS10940	COG0482	sulfurtransferase activity
DK41_RS10945	COG1760	l-serine dehydratase
DK41_RS10950	COG1760	l-serine dehydratase
DK41_RS10960	COG0741	lytic transglycosylase activity
DK41_RS10985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK41_RS10990	COG0612	Peptidase, M16
DK41_RS10995	COG0612	Peptidase, M16
DK41_RS11000	COG2501	S4 domain
DK41_RS11015	COG3344	reverse transcriptase
DK41_RS11030	COG0517	IMP dehydrogenase activity
DK41_RS11030	COG0516	GMP reductase activity
DK41_RS11040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK41_RS11055	COG0454	-acetyltransferase
DK41_RS11070	COG0549	Belongs to the carbamate kinase family
DK41_RS11090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK41_RS11095	COG0488	(ABC) transporter
DK41_RS11100	COG4485	Bacterial membrane protein, YfhO
DK41_RS11120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DK41_RS11125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK41_RS11130	COG1475	DNA binding