locus-tag	class	description
HQ616_RS00010	COG0592	DNA-directed DNA polymerase activity
HQ616_RS00030	COG0012	GTP binding
HQ616_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HQ616_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HQ616_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQ616_RS00260	COG0436	Aminotransferase
HQ616_RS00275	COG0416	fatty acid biosynthetic process
HQ616_RS00285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HQ616_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQ616_RS00300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQ616_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQ616_RS00315	COG0138	bifunctional purine biosynthesis protein purh
HQ616_RS00330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HQ616_RS00340	COG1175	transmembrane transport
HQ616_RS00345	COG0395	ABC-type sugar transport system, permease component
HQ616_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQ616_RS00370	COG3458	cephalosporin-C deacetylase activity
HQ616_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQ616_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQ616_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HQ616_RS00425	COG2755	lipolytic protein G-D-S-L family
HQ616_RS00425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HQ616_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
HQ616_RS00430	COG1454	alcohol dehydrogenase
HQ616_RS00435	COG1064	alcohol dehydrogenase
HQ616_RS00445	COG0534	Mate efflux family protein
HQ616_RS00555	COG0201	protein transport
HQ616_RS00560	COG0563	adenylate kinase activity
HQ616_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQ616_RS00585	COG0202	RNA polymerase activity
HQ616_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ616_RS00745	COG0443	Heat shock 70 kDa protein
HQ616_RS00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQ616_RS00765	COG0351	phosphomethylpyrimidine kinase
HQ616_RS00770	COG4720	Psort location CytoplasmicMembrane, score
HQ616_RS00780	COG0668	transmembrane transport
HQ616_RS00810	COG0756	dUTP diphosphatase activity
HQ616_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ616_RS00835	COG1879	ABC-type sugar transport system periplasmic component
HQ616_RS00840	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQ616_RS00855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQ616_RS00860	COG1609	Transcriptional regulator
HQ616_RS00865	COG0577	efflux transmembrane transporter activity
HQ616_RS00870	COG1136	(ABC) transporter
HQ616_RS00875	COG0745	RESPONSE REGULATOR receiver
HQ616_RS00880	COG5002	protein histidine kinase activity
HQ616_RS00895	COG0191	fructose-bisphosphate aldolase activity
HQ616_RS00915	COG1461	Dihydroxyacetone kinase
HQ616_RS00935	COG1126	abc transporter atp-binding protein
HQ616_RS00940	COG0765	amino acid transport
HQ616_RS00960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQ616_RS00970	COG0719	Fe-S assembly protein
HQ616_RS00975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQ616_RS00985	COG0719	Fe-S assembly protein
HQ616_RS00990	COG1686	Belongs to the peptidase S11 family
HQ616_RS00995	COG1686	Belongs to the peptidase S11 family
HQ616_RS01000	COG4166	transmembrane transport
HQ616_RS01005	COG0601	transmembrane transport
HQ616_RS01010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ616_RS01015	COG0444	Belongs to the ABC transporter superfamily
HQ616_RS01020	COG4608	Belongs to the ABC transporter superfamily
HQ616_RS01060	COG1121	(ABC) transporter
HQ616_RS01065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQ616_RS01080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ616_RS01080	COG4499	WXG100 protein secretion system (Wss), protein YukC
HQ616_RS01100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQ616_RS01105	COG1459	type II secretion system
HQ616_RS01165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQ616_RS01170	COG1363	Peptidase, m42
HQ616_RS01185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQ616_RS01190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ616_RS01205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ616_RS01225	COG1346	cytolysis
HQ616_RS01235	COG0601	transmembrane transport
HQ616_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ616_RS01245	COG1122	ATPase activity
HQ616_RS01250	COG1124	(ABC) transporter
HQ616_RS01255	COG1263	PTS System
HQ616_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS01260	COG0366	Alpha amylase catalytic
HQ616_RS01265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ616_RS01280	COG3959	Transketolase, thiamine diphosphate binding domain
HQ616_RS01285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQ616_RS01290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HQ616_RS01310	COG1045	serine acetyltransferase
HQ616_RS01325	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HQ616_RS01350	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQ616_RS01360	COG4974	Belongs to the 'phage' integrase family
HQ616_RS01440	COG1674	ftsk spoiiie
HQ616_RS01460	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HQ616_RS01465	COG3421	Type III restriction
HQ616_RS01505	COG1396	sequence-specific DNA binding
HQ616_RS01510	COG2814	Major facilitator Superfamily
HQ616_RS01520	COG1732	Glycine betaine
HQ616_RS01650	COG0519	Catalyzes the synthesis of GMP from XMP
HQ616_RS01695	COG1695	Transcriptional regulator
HQ616_RS01710	COG1755	Isoprenylcysteine carboxyl methyltransferase
HQ616_RS01750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ616_RS01755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQ616_RS01775	COG1131	(ABC) transporter
HQ616_RS01785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS01785	COG1263	PTS System
HQ616_RS01785	COG2190	(PTS) system
HQ616_RS01790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HQ616_RS01810	COG0768	penicillin binding
HQ616_RS01820	COG0513	Belongs to the DEAD box helicase family
HQ616_RS01835	COG1126	abc transporter atp-binding protein
HQ616_RS01845	COG0492	ferredoxin-NADP+ reductase activity
HQ616_RS01850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HQ616_RS01860	COG3579	cysteine-type endopeptidase activity
HQ616_RS01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ616_RS01890	COG0116	Belongs to the methyltransferase superfamily
HQ616_RS01900	COG1854	S-ribosylhomocysteine lyase activity
HQ616_RS01905	COG1418	mRNA catabolic process
HQ616_RS01905	COG4372	Transposase
HQ616_RS01910	COG1131	(ABC) transporter
HQ616_RS01920	COG4585	Histidine kinase
HQ616_RS01925	COG2197	response regulator
HQ616_RS01935	COG0194	GDP metabolic process
HQ616_RS01945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQ616_RS01950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQ616_RS01955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ616_RS01955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ616_RS01965	COG2815	serine threonine protein kinase
HQ616_RS01965	COG0515	serine threonine protein kinase
HQ616_RS01975	COG4585	Histidine kinase
HQ616_RS01980	COG2197	response regulator
HQ616_RS01990	COG1098	S1 RNA binding domain
HQ616_RS01995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ616_RS02000	COG1349	DNA-binding transcription factor activity
HQ616_RS02010	COG1447	Phosphotransferase system cellobiose-specific component IIA
HQ616_RS02020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HQ616_RS02025	COG1882	Formate acetyltransferase
HQ616_RS02045	COG1739	Uncharacterized protein family UPF0029
HQ616_RS02050	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HQ616_RS02055	COG1040	competence protein
HQ616_RS02090	COG0527	aspartate kinase activity
HQ616_RS02095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQ616_RS02100	COG1024	Enoyl-CoA hydratase
HQ616_RS02110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQ616_RS02120	COG2070	2-Nitropropane dioxygenase
HQ616_RS02125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HQ616_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
HQ616_RS02135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ616_RS02150	COG0439	Biotin carboxylase
HQ616_RS02170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQ616_RS02185	COG3716	PTS system mannose fructose sorbose family IID component
HQ616_RS02190	COG3715	PTS system
HQ616_RS02200	COG0561	phosphatase activity
HQ616_RS02215	COG2252	PERMEase
HQ616_RS02220	COG0802	atpase or kinase
HQ616_RS02230	COG1316	TRANSCRIPTIONal
HQ616_RS02240	COG0537	adenosine 5'-monophosphoramidase activity
HQ616_RS02255	COG1131	(ABC) transporter
HQ616_RS02260	COG4473	ABC transporter
HQ616_RS02270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQ616_RS02285	COG0195	Participates in both transcription termination and antitermination
HQ616_RS02290	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HQ616_RS02300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQ616_RS02305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQ616_RS02330	COG2860	membrane
HQ616_RS02340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ616_RS02340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ616_RS02345	COG1832	CoA-binding protein
HQ616_RS02365	COG5002	protein histidine kinase activity
HQ616_RS02385	COG1268	BioY protein
HQ616_RS02390	COG1234	tRNA 3'-trailer cleavage
HQ616_RS02405	COG0166	Belongs to the GPI family
HQ616_RS02410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQ616_RS02415	COG0457	Tetratricopeptide repeat
HQ616_RS02415	COG0705	Rhomboid family
HQ616_RS02420	COG1744	ABC transporter substrate-binding protein PnrA-like
HQ616_RS02425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQ616_RS02510	COG2153	protein acetylation
HQ616_RS02520	COG1442	glycosyl transferase family 8
HQ616_RS02520	COG1216	Glycosyl transferase, family 2
HQ616_RS02570	COG0789	Transcriptional regulator
HQ616_RS02580	COG0656	L-ascorbic acid biosynthetic process
HQ616_RS02630	COG0582	viral genome integration into host DNA
HQ616_RS02665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HQ616_RS02675	COG0525	valine-tRNA ligase activity
HQ616_RS02685	COG0673	inositol 2-dehydrogenase activity
HQ616_RS02695	COG2315	Protein conserved in bacteria
HQ616_RS02700	COG2502	aspartate--ammonia ligase
HQ616_RS02710	COG0742	ribosomal rna small subunit methyltransferase
HQ616_RS02720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQ616_RS02725	COG3480	Lon protease (S16) C-terminal proteolytic domain
HQ616_RS02730	COG0737	Belongs to the 5'-nucleotidase family
HQ616_RS02735	COG4470	Protein conserved in bacteria
HQ616_RS02750	COG1132	(ABC) transporter
HQ616_RS02755	COG1132	(ABC) transporter
HQ616_RS02760	COG0512	Glutamine amidotransferase of anthranilate synthase
HQ616_RS02765	COG1268	BioY protein
HQ616_RS02770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQ616_RS02800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQ616_RS02815	COG1940	carbohydrate kinase activity
HQ616_RS02820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQ616_RS02825	COG1217	gtp-binding protein TYPA
HQ616_RS02855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQ616_RS02860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQ616_RS02870	COG0762	integral membrane protein
HQ616_RS02875	COG2302	S4 RNA-binding domain
HQ616_RS02880	COG3599	regulation of cell shape
HQ616_RS02895	COG0494	nUDIX hydrolase
HQ616_RS02900	COG0542	response to heat
HQ616_RS02905	COG4703	Protein of unknown function (DUF1797)
HQ616_RS02910	COG0765	amino acid transport
HQ616_RS02915	COG1126	abc transporter atp-binding protein
HQ616_RS02920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQ616_RS02930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HQ616_RS02940	COG1722	exodeoxyribonuclease VII activity
HQ616_RS02950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HQ616_RS02955	COG1438	arginine binding
HQ616_RS02960	COG0497	DNA recombination
HQ616_RS02965	COG1307	EDD domain protein, DegV family
HQ616_RS02970	COG2755	lipolytic protein G-D-S-L family
HQ616_RS03015	COG1078	dGTPase activity
HQ616_RS03040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HQ616_RS03050	COG2884	Cell division ATP-binding protein ftsE
HQ616_RS03055	COG2177	Part of the ABC transporter FtsEX involved in
HQ616_RS03075	COG1199	ATP-dependent helicase activity
HQ616_RS03075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQ616_RS03080	COG0436	Aminotransferase
HQ616_RS03085	COG0017	Asparaginyl-tRNA synthetase
HQ616_RS03105	COG1660	Displays ATPase and GTPase activities
HQ616_RS03130	COG0254	rRNA binding
HQ616_RS03135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HQ616_RS03140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HQ616_RS03145	COG0716	FMN binding
HQ616_RS03150	COG1605	Chorismate mutase
HQ616_RS03150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HQ616_RS03155	COG0038	chloride channel
HQ616_RS03160	COG0335	large ribosomal subunit rRNA binding
HQ616_RS03195	COG1136	(ABC) transporter
HQ616_RS03210	COG5002	protein histidine kinase activity
HQ616_RS03230	COG0772	Belongs to the SEDS family
HQ616_RS03250	COG0560	Phosphoserine phosphatase
HQ616_RS03265	COG0148	phosphopyruvate hydratase activity
HQ616_RS03285	COG1316	TRANSCRIPTIONal
HQ616_RS03350	COG0791	NLP P60 protein
HQ616_RS03350	COG0741	lytic transglycosylase activity
HQ616_RS03380	COG2946	Replication initiation factor
HQ616_RS03390	COG1674	ftsk spoiiie
HQ616_RS03430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ616_RS03430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQ616_RS03480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HQ616_RS03500	COG0270	DNA (cytosine-5-)-methyltransferase activity
HQ616_RS03540	COG0740	serine-type endopeptidase activity
HQ616_RS03620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HQ616_RS03645	COG3700	Belongs to the class B bacterial acid phosphatase family
HQ616_RS03755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HQ616_RS03760	COG4555	ABC transporter
HQ616_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
HQ616_RS03790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ616_RS03795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQ616_RS03815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQ616_RS03820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQ616_RS03840	COG3064	Membrane
HQ616_RS03840	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HQ616_RS03900	COG1136	(ABC) transporter
HQ616_RS03915	COG0586	Pfam SNARE associated Golgi protein
HQ616_RS03920	COG4619	ABC transporter
HQ616_RS03925	COG0390	transport system, permease component
HQ616_RS03935	COG0583	DNA-binding transcription factor activity
HQ616_RS03945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ616_RS03950	COG2211	Major facilitator Superfamily
HQ616_RS03960	COG3250	beta-galactosidase activity
HQ616_RS03965	COG2186	Transcriptional regulator
HQ616_RS03970	COG0800	Aldolase
HQ616_RS03975	COG1904	glucuronate isomerase
HQ616_RS03980	COG1312	Catalyzes the dehydration of D-mannonate
HQ616_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
HQ616_RS04005	COG1609	Transcriptional regulator
HQ616_RS04020	COG0438	transferase activity, transferring glycosyl groups
HQ616_RS04025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQ616_RS04045	COG0765	amino acid transport
HQ616_RS04050	COG0765	amino acid transport
HQ616_RS04055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ616_RS04060	COG1126	abc transporter atp-binding protein
HQ616_RS04065	COG0745	RESPONSE REGULATOR receiver
HQ616_RS04070	COG5002	protein histidine kinase activity
HQ616_RS04075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HQ616_RS04080	COG2832	Protein of unknown function (DUF454)
HQ616_RS04090	COG1196	nuclear chromosome segregation
HQ616_RS04095	COG0561	phosphatase activity
HQ616_RS04100	COG0561	phosphatase activity
HQ616_RS04105	COG0552	protein localization to endoplasmic reticulum
HQ616_RS04110	COG3689	TIGRFAM TIGR03943 family protein
HQ616_RS04115	COG0701	Predicted permease
HQ616_RS04130	COG2183	response to ionizing radiation
HQ616_RS04135	COG3091	SprT-like family
HQ616_RS04140	COG1983	PspC domain protein
HQ616_RS04175	COG0826	peptidase U32
HQ616_RS04180	COG4443	Transcriptional Coactivator p15 (PC4)
HQ616_RS04190	COG1914	H( )-stimulated, divalent metal cation uptake system
HQ616_RS04205	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ616_RS04205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HQ616_RS04230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HQ616_RS04255	COG1164	Oligoendopeptidase f
HQ616_RS04265	COG0772	Belongs to the SEDS family
HQ616_RS04285	COG0768	penicillin binding
HQ616_RS04300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQ616_RS04305	COG2223	nitrite transmembrane transporter activity
HQ616_RS04330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQ616_RS04335	COG2011	ABC-type metal ion transport system permease component
HQ616_RS04340	COG1464	Belongs to the NlpA lipoprotein family
HQ616_RS04345	COG0513	Belongs to the DEAD box helicase family
HQ616_RS04355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HQ616_RS04360	COG0204	Acyl-transferase
HQ616_RS04365	COG1555	photosystem II stabilization
HQ616_RS04365	COG1596	polysaccharide export
HQ616_RS04370	COG0658	competence protein
HQ616_RS04370	COG2333	competence protein COMEC
HQ616_RS04375	COG0561	phosphatase activity
HQ616_RS04380	COG1609	Transcriptional regulator
HQ616_RS04385	COG0657	acetylesterase activity
HQ616_RS04390	COG2226	methyltransferase
HQ616_RS04400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HQ616_RS04405	COG3711	transcriptional antiterminator
HQ616_RS04410	COG2190	(PTS) system
HQ616_RS04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS04410	COG1263	PTS System
HQ616_RS04420	COG3835	regulator
HQ616_RS04425	COG1929	Belongs to the glycerate kinase type-1 family
HQ616_RS04430	COG2610	gluconate transmembrane transporter activity
HQ616_RS04440	COG1846	Transcriptional regulator
HQ616_RS04455	COG0363	glucosamine-6-phosphate deaminase activity
HQ616_RS04460	COG0435	Glutathione S-transferase
HQ616_RS04465	COG1187	pseudouridine synthase activity
HQ616_RS04485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HQ616_RS04490	COG4122	O-methyltransferase activity
HQ616_RS04500	COG4894	glucomannan catabolic process
HQ616_RS04510	COG1811	Na channel or pump
HQ616_RS04515	COG1442	glycosyl transferase family 8
HQ616_RS04530	COG1476	TRANSCRIPTIONal
HQ616_RS04545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ616_RS04550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQ616_RS04555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQ616_RS04570	COG1012	belongs to the aldehyde dehydrogenase family
HQ616_RS04575	COG0726	polysaccharide deacetylase
HQ616_RS04590	COG1956	GAF domain-containing protein
HQ616_RS04595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HQ616_RS04605	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HQ616_RS04605	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HQ616_RS04635	COG4721	ABC-type cobalt transport system, permease component
HQ616_RS04640	COG1122	ATPase activity
HQ616_RS04650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HQ616_RS04680	COG4109	DRTGG domain
HQ616_RS04685	COG0024	Methionine aminopeptidase
HQ616_RS04695	COG2246	polysaccharide biosynthetic process
HQ616_RS04700	COG4708	membrane
HQ616_RS04710	COG1597	lipid kinase activity
HQ616_RS04715	COG1523	belongs to the glycosyl hydrolase 13 family
HQ616_RS04730	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQ616_RS04810	COG0072	phenylalanine-tRNA ligase activity
HQ616_RS04810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ616_RS04815	COG2321	neutral zinc metallopeptidase
HQ616_RS04840	COG0488	(ABC) transporter
HQ616_RS04845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HQ616_RS04850	COG0022	dehydrogenase e1 component
HQ616_RS04850	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ616_RS04855	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQ616_RS04865	COG0095	Lipoate-protein ligase
HQ616_RS04870	COG3442	glutamine amidotransferase
HQ616_RS04875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQ616_RS04880	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HQ616_RS04905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQ616_RS04915	COG0647	UMP catabolic process
HQ616_RS04925	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HQ616_RS04930	COG1518	maintenance of DNA repeat elements
HQ616_RS04935	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HQ616_RS04950	COG0481	GTPase activity
HQ616_RS04960	COG1418	mRNA catabolic process
HQ616_RS04965	COG0456	acetyltransferase
HQ616_RS05005	COG1131	(ABC) transporter
HQ616_RS05010	COG1725	Transcriptional regulator
HQ616_RS05020	COG0205	6-phosphofructokinase activity
HQ616_RS05025	COG0469	pyruvate kinase activity
HQ616_RS05035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HQ616_RS05040	COG2824	Alkylphosphonate utilization operon protein PhnA
HQ616_RS05045	COG0765	amino acid transport
HQ616_RS05050	COG1126	abc transporter atp-binding protein
HQ616_RS05065	COG1072	(Pantothenic acid kinase))
HQ616_RS05070	COG2813	Specifically methylates the guanine in position
HQ616_RS05080	COG1744	ABC transporter substrate-binding protein PnrA-like
HQ616_RS05085	COG3845	ABC transporter
HQ616_RS05090	COG4603	Belongs to the binding-protein-dependent transport system permease family
HQ616_RS05095	COG1079	Belongs to the binding-protein-dependent transport system permease family
HQ616_RS05115	COG3764	Sortase (surface protein transpeptidase)
HQ616_RS05120	COG0346	lactoylglutathione lyase activity
HQ616_RS05200	COG2188	Transcriptional regulator
HQ616_RS05215	COG1464	Belongs to the NlpA lipoprotein family
HQ616_RS05230	COG1136	(ABC) transporter
HQ616_RS05240	COG0745	RESPONSE REGULATOR receiver
HQ616_RS05245	COG5002	protein histidine kinase activity
HQ616_RS05250	COG4974	Belongs to the 'phage' integrase family
HQ616_RS05270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQ616_RS05275	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HQ616_RS05280	COG5002	protein histidine kinase activity
HQ616_RS05285	COG0745	RESPONSE REGULATOR receiver
HQ616_RS05295	COG0704	Plays a role in the regulation of phosphate uptake
HQ616_RS05300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ616_RS05305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ616_RS05310	COG0581	inorganic phosphate transmembrane transporter activity
HQ616_RS05315	COG0573	inorganic phosphate transmembrane transporter activity
HQ616_RS05325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQ616_RS05325	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HQ616_RS05330	COG0483	inositol monophosphate 1-phosphatase activity
HQ616_RS05345	COG0196	riboflavin kinase activity
HQ616_RS05350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQ616_RS05380	COG1136	(ABC) transporter
HQ616_RS05385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQ616_RS05390	COG0758	DNA mediated transformation
HQ616_RS05395	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HQ616_RS05400	COG4604	ABC transporter, ATP-binding protein
HQ616_RS05405	COG4605	iron ion homeostasis
HQ616_RS05410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ616_RS05415	COG0110	maltose O-acetyltransferase activity
HQ616_RS05425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQ616_RS05430	COG1376	ErfK ybiS ycfS ynhG family protein
HQ616_RS05435	COG1966	Carbon starvation protein
HQ616_RS05440	COG3279	Response regulator of the LytR AlgR family
HQ616_RS05445	COG3275	phosphorelay sensor kinase activity
HQ616_RS05470	COG3942	CHAP domain
HQ616_RS05470	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ616_RS05590	COG0505	Belongs to the CarA family
HQ616_RS05620	COG0488	(ABC) transporter
HQ616_RS05630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQ616_RS05645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQ616_RS05650	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HQ616_RS05685	COG0095	Lipoate-protein ligase
HQ616_RS05695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HQ616_RS05700	COG4684	Psort location CytoplasmicMembrane, score
HQ616_RS05705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQ616_RS05715	COG1132	(ABC) transporter
HQ616_RS05735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQ616_RS05745	COG2890	protein-(glutamine-N5) methyltransferase activity
HQ616_RS05750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQ616_RS05760	COG1942	4-Oxalocrotonate Tautomerase
HQ616_RS05775	COG0431	NADPH-dependent FMN reductase
HQ616_RS05775	COG1053	succinate dehydrogenase
HQ616_RS05775	COG3976	FMN-binding domain protein
HQ616_RS05785	COG2233	PERMEase
HQ616_RS05795	COG0516	GMP reductase activity
HQ616_RS05800	COG0477	Major facilitator Superfamily
HQ616_RS05815	COG4221	oxidoreductase activity
HQ616_RS05820	COG0280	phosphate acetyltransferase
HQ616_RS05825	COG0564	pseudouridine synthase activity
HQ616_RS05830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQ616_RS05835	COG2357	RelA SpoT domain protein
HQ616_RS05850	COG1104	cysteine desulfurase activity
HQ616_RS05860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HQ616_RS05865	COG2003	Belongs to the UPF0758 family
HQ616_RS05870	COG0628	permease
HQ616_RS05875	COG2723	6-phospho-beta-galactosidase activity
HQ616_RS05885	COG0561	phosphatase activity
HQ616_RS05895	COG0038	chloride channel
HQ616_RS05905	COG1177	transmembrane transport
HQ616_RS05910	COG1176	ABC-type spermidine putrescine transport system, permease component I
HQ616_RS05920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQ616_RS05925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HQ616_RS05945	COG0285	dihydrofolate synthase activity
HQ616_RS05950	COG2962	Rard protein
HQ616_RS05965	COG0726	polysaccharide deacetylase
HQ616_RS05970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HQ616_RS05975	COG1012	belongs to the aldehyde dehydrogenase family
HQ616_RS06060	COG2261	transglycosylase associated protein
HQ616_RS06085	COG1115	amino acid carrier protein
HQ616_RS06090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HQ616_RS06100	COG1346	cytolysis
HQ616_RS06130	COG4974	Belongs to the 'phage' integrase family
HQ616_RS06140	COG0539	negative regulation of cytoplasmic translation
HQ616_RS06160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQ616_RS06170	COG0187	DNA topoisomerase II activity
HQ616_RS06175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQ616_RS06180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQ616_RS06190	COG2755	lipolytic protein G-D-S-L family
HQ616_RS06190	COG1083	cytidylyl-transferase
HQ616_RS06205	COG2089	acid synthase
HQ616_RS06220	COG1442	glycosyl transferase family 8
HQ616_RS06220	COG1216	Glycosyl transferase, family 2
HQ616_RS06225	COG1215	transferase activity, transferring glycosyl groups
HQ616_RS06230	COG0463	Glycosyl transferase, family 2
HQ616_RS06250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQ616_RS06275	COG1316	TRANSCRIPTIONal
HQ616_RS06300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HQ616_RS06335	COG3842	ATPase activity
HQ616_RS06350	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HQ616_RS06355	COG3527	Alpha-acetolactate decarboxylase
HQ616_RS06360	COG0028	Belongs to the TPP enzyme family
HQ616_RS06365	COG0457	Tetratricopeptide repeat
HQ616_RS06370	COG0628	permease
HQ616_RS06380	COG1051	belongs to the nudix hydrolase family
HQ616_RS06385	COG5492	domain, Protein
HQ616_RS06390	COG1088	dTDP-glucose 4,6-dehydratase activity
HQ616_RS06400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HQ616_RS06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQ616_RS06415	COG2384	SAM-dependent methyltransferase
HQ616_RS06430	COG1621	beta-fructofuranosidase activity
HQ616_RS06435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HQ616_RS06435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HQ616_RS06440	COG0300	oxidoreductase activity
HQ616_RS06455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQ616_RS06490	COG1573	uracil-dna glycosylase
HQ616_RS06495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQ616_RS06505	COG0584	glycerophosphoryl diester phosphodiesterase
HQ616_RS06520	COG0534	Mate efflux family protein
HQ616_RS06560	COG0803	Belongs to the bacterial solute-binding protein 9 family
HQ616_RS06580	COG2176	DNA-directed DNA polymerase activity
HQ616_RS06590	COG4974	Belongs to the 'phage' integrase family
HQ616_RS06615	COG1674	ftsk spoiiie
HQ616_RS06655	COG2040	homocysteine
HQ616_RS06660	COG0833	amino acid
HQ616_RS06690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HQ616_RS06700	COG3425	synthase
HQ616_RS06715	COG1272	protein, Hemolysin III
HQ616_RS06760	COG0745	RESPONSE REGULATOR receiver
HQ616_RS06765	COG2357	RelA SpoT domain protein
HQ616_RS06770	COG1132	(ABC) transporter
HQ616_RS06785	COG0737	Belongs to the 5'-nucleotidase family
HQ616_RS06790	COG0242	peptide deformylase activity
HQ616_RS06795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HQ616_RS06805	COG1132	(ABC) transporter
HQ616_RS06820	COG0488	(ABC) transporter
HQ616_RS06850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ616_RS06850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ616_RS06850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ616_RS06855	COG1105	Belongs to the carbohydrate kinase PfkB family
HQ616_RS06860	COG1349	DNA-binding transcription factor activity
HQ616_RS06865	COG1388	LysM domain
HQ616_RS06865	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ616_RS06915	COG1837	Belongs to the UPF0109 family
HQ616_RS06920	COG0228	four-way junction DNA binding
HQ616_RS06925	COG0577	efflux transmembrane transporter activity
HQ616_RS06930	COG1136	(ABC) transporter
HQ616_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQ616_RS06945	COG0505	Belongs to the CarA family
HQ616_RS06955	COG0564	pseudouridine synthase activity
HQ616_RS06965	COG0583	DNA-binding transcription factor activity
HQ616_RS06970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQ616_RS06990	COG0301	tRNA thio-modification
HQ616_RS06995	COG1104	cysteine desulfurase activity
HQ616_RS07005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQ616_RS07030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQ616_RS07035	COG1368	sulfuric ester hydrolase activity
HQ616_RS07040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HQ616_RS07050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQ616_RS07080	COG2244	polysaccharide biosynthetic process
HQ616_RS07090	COG1120	ATPase activity
HQ616_RS07095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQ616_RS07100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ616_RS07105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQ616_RS07120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HQ616_RS07125	COG1253	flavin adenine dinucleotide binding
HQ616_RS07130	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HQ616_RS07135	COG1242	4 iron, 4 sulfur cluster binding
HQ616_RS07140	COG0671	phosphoesterase, PA-phosphatase related
HQ616_RS07145	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HQ616_RS07180	COG0297	glycogen (starch) synthase activity
HQ616_RS07220	COG3475	LICD family
HQ616_RS07235	COG0463	Glycosyl transferase, family 2
HQ616_RS07240	COG1215	transferase activity, transferring glycosyl groups
HQ616_RS07250	COG1091	dTDP-4-dehydrorhamnose reductase activity
HQ616_RS07255	COG2151	metal-sulfur cluster biosynthetic enzyme
HQ616_RS07260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQ616_RS07265	COG0358	DNA primase activity
HQ616_RS07270	COG1970	mechanosensitive ion channel activity
HQ616_RS07285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ616_RS07290	COG0004	ammonium transporteR
HQ616_RS07300	COG1054	Belongs to the UPF0176 family
HQ616_RS07310	COG2271	Major facilitator Superfamily
HQ616_RS07315	COG0058	SHG alpha-glucan phosphorylase activity
HQ616_RS07320	COG1640	4-alpha-glucanotransferase
HQ616_RS07325	COG1609	Transcriptional regulator
HQ616_RS07335	COG1175	transmembrane transport
HQ616_RS07340	COG3833	ABC-type maltose transport systems, permease component
HQ616_RS07345	COG3104	oligopeptide transport
HQ616_RS07365	COG0438	transferase activity, transferring glycosyl groups
HQ616_RS07395	COG1442	glycosyl transferase family 8
HQ616_RS07400	COG1216	Glycosyl transferase, family 2
HQ616_RS07400	COG1442	glycosyl transferase family 8
HQ616_RS07405	COG1442	glycosyl transferase family 8
HQ616_RS07410	COG1216	Glycosyl transferase, family 2
HQ616_RS07410	COG1442	glycosyl transferase family 8
HQ616_RS07415	COG1442	glycosyl transferase family 8
HQ616_RS07455	COG0765	amino acid transport
HQ616_RS07460	COG1126	abc transporter atp-binding protein
HQ616_RS07485	COG2309	aminopeptidase activity
HQ616_RS07500	COG1187	pseudouridine synthase activity
HQ616_RS07505	COG0656	L-ascorbic acid biosynthetic process
HQ616_RS07510	COG0778	Nitroreductase
HQ616_RS07515	COG0346	lactoylglutathione lyase activity
HQ616_RS07520	COG0463	Glycosyl transferase, family 2
HQ616_RS07525	COG1113	amino acid transport
HQ616_RS07530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQ616_RS07535	COG0557	exoribonuclease II activity
HQ616_RS07550	COG2814	Major facilitator Superfamily
HQ616_RS07560	COG1131	(ABC) transporter
HQ616_RS07570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQ616_RS07575	COG1396	sequence-specific DNA binding
HQ616_RS07625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQ616_RS07630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQ616_RS07650	COG1702	phosphate starvation-inducible protein PhoH
HQ616_RS07675	COG0233	cytoplasmic translational termination
HQ616_RS07690	COG0444	Belongs to the ABC transporter superfamily
HQ616_RS07695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQ616_RS07700	COG0601	transmembrane transport
HQ616_RS07705	COG0747	negative chemotaxis
HQ616_RS07710	COG0081	regulation of translation
HQ616_RS07715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQ616_RS07725	COG1473	amidohydrolase
HQ616_RS07730	COG0583	DNA-binding transcription factor activity
HQ616_RS07740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQ616_RS07745	COG1674	ftsk spoiiie
HQ616_RS07750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQ616_RS07775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQ616_RS07805	COG0673	inositol 2-dehydrogenase activity
HQ616_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
HQ616_RS07865	COG1114	Component of the transport system for branched-chain amino acids
HQ616_RS07870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ616_RS07870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQ616_RS07885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HQ616_RS07895	COG0708	Exodeoxyribonuclease III
HQ616_RS07900	COG1393	Belongs to the ArsC family
HQ616_RS07905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HQ616_RS07910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ616_RS07920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HQ616_RS07940	COG0470	DNA polymerase III
HQ616_RS07950	COG0517	IMP dehydrogenase activity
HQ616_RS07990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQ616_RS07995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQ616_RS08005	COG0531	amino acid
HQ616_RS08010	COG0569	domain protein
HQ616_RS08015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ616_RS08025	COG1187	pseudouridine synthase activity
HQ616_RS08060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQ616_RS08075	COG1827	regulation of RNA biosynthetic process
HQ616_RS08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQ616_RS08095	COG1254	Belongs to the acylphosphatase family
HQ616_RS08105	COG0765	amino acid transport
HQ616_RS08110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ616_RS08125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HQ616_RS08155	COG1484	DNA-dependent DNA replication
HQ616_RS08170	COG5002	protein histidine kinase activity
HQ616_RS08175	COG0745	RESPONSE REGULATOR receiver
HQ616_RS08190	COG1704	LemA family
HQ616_RS08195	COG0357	Ribosomal RNA small subunit methyltransferase G
HQ616_RS08200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQ616_RS08205	COG0569	domain protein
HQ616_RS08230	COG1114	Component of the transport system for branched-chain amino acids
HQ616_RS08235	COG1063	alcohol dehydrogenase
HQ616_RS08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQ616_RS08265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQ616_RS08270	COG0217	transcriptional regulatory protein
HQ616_RS08275	COG2376	Dihydroxyacetone kinase
HQ616_RS08280	COG1309	transcriptional regulator
HQ616_RS08285	COG2376	Dihydroxyacetone kinase
HQ616_RS08290	COG1461	Dihydroxyacetone kinase
HQ616_RS08295	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HQ616_RS08300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ616_RS08310	COG0789	Transcriptional regulator
HQ616_RS08325	COG2226	methyltransferase
HQ616_RS08330	COG0799	negative regulation of ribosome biogenesis
HQ616_RS08340	COG1713	HD superfamily hydrolase involved in NAD metabolism
HQ616_RS08345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQ616_RS08350	COG1534	Rna-binding protein
HQ616_RS08355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQ616_RS08360	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HQ616_RS08385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQ616_RS08385	COG0574	Belongs to the PEP-utilizing enzyme family
HQ616_RS08395	COG0517	IMP dehydrogenase activity
HQ616_RS08410	COG1335	isochorismatase
HQ616_RS08415	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HQ616_RS08420	COG0436	Aminotransferase
HQ616_RS08425	COG0589	response to stress
HQ616_RS08430	COG0561	phosphatase activity
HQ616_RS08435	COG0252	asparaginase activity
HQ616_RS08445	COG4989	oxidoreductase activity
HQ616_RS08450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HQ616_RS08455	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ616_RS08455	COG3942	CHAP domain
HQ616_RS08465	COG0736	holo-[acyl-carrier-protein] synthase activity
HQ616_RS08470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQ616_RS08480	COG1482	cell wall glycoprotein biosynthetic process
HQ616_RS08485	COG1940	carbohydrate kinase activity
HQ616_RS08490	COG2190	(PTS) system
HQ616_RS08490	COG1263	PTS System
HQ616_RS08490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS08495	COG1621	beta-fructofuranosidase activity
HQ616_RS08500	COG1609	Transcriptional regulator
HQ616_RS08505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQ616_RS08515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HQ616_RS08540	COG2131	deaminase
HQ616_RS08545	COG0006	proline dipeptidase activity
HQ616_RS08555	COG2814	Major facilitator Superfamily
HQ616_RS08580	COG0629	single-stranded DNA binding
HQ616_RS08585	COG0360	Binds together with S18 to 16S ribosomal RNA
HQ616_RS08590	COG1194	a g-specific adenine glycosylase
HQ616_RS08600	COG3118	belongs to the thioredoxin family
HQ616_RS08625	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQ616_RS08630	COG0681	Belongs to the peptidase S26 family
HQ616_RS08635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HQ616_RS08650	COG1882	Formate acetyltransferase
HQ616_RS08660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HQ616_RS08675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQ616_RS08685	COG2814	Major facilitator Superfamily
HQ616_RS08690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ616_RS08705	COG0142	geranyltranstransferase activity
HQ616_RS08710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HQ616_RS08715	COG4988	ABC transporter
HQ616_RS08720	COG1294	oxidase, subunit
HQ616_RS08725	COG1271	oxidase subunit
HQ616_RS08730	COG1252	NADH dehydrogenase
HQ616_RS08770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQ616_RS08775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ616_RS08775	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HQ616_RS08775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ616_RS08780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ616_RS08785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQ616_RS08790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQ616_RS08790	COG3711	transcriptional antiterminator
HQ616_RS08810	COG4221	oxidoreductase activity
HQ616_RS08820	COG0656	L-ascorbic acid biosynthetic process
HQ616_RS08825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HQ616_RS08840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQ616_RS08845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQ616_RS08850	COG0789	Transcriptional regulator
HQ616_RS08865	COG2081	HI0933 family
HQ616_RS08890	COG0456	acetyltransferase
HQ616_RS08895	COG1214	PFAM Peptidase M22, glycoprotease
HQ616_RS08910	COG3942	CHAP domain
HQ616_RS08915	COG0174	glutamine synthetase
HQ616_RS08920	COG0789	Transcriptional regulator
HQ616_RS08935	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HQ616_RS08960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQ616_RS08985	COG1162	GTPase activity
HQ616_RS09010	COG0084	hydrolase, TatD family'
HQ616_RS09035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HQ616_RS09040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQ616_RS09045	COG1696	Membrane protein involved in D-alanine export
HQ616_RS09065	COG0745	RESPONSE REGULATOR receiver
HQ616_RS09075	COG3314	Sporulation integral membrane protein YlbJ
HQ616_RS09085	COG3448	diguanylate cyclase activity
HQ616_RS09085	COG4175	Glycine betaine
HQ616_RS09090	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HQ616_RS09110	COG1070	Carbohydrate kinase
HQ616_RS09120	COG3775	system Galactitol-specific IIC component
HQ616_RS09125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQ616_RS09135	COG1609	Transcriptional regulator
HQ616_RS09225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQ616_RS09230	COG1428	Deoxynucleoside kinase
HQ616_RS09240	COG0542	response to heat
HQ616_RS09245	COG4463	regulation of RNA biosynthetic process
HQ616_RS09255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQ616_RS09265	COG0450	alkyl hydroperoxide reductase
HQ616_RS09280	COG0025	NhaP-type Na H and K H
HQ616_RS09290	COG1619	proteins homologs of microcin C7 resistance protein MccF
HQ616_RS09295	COG3590	peptidase
HQ616_RS09320	COG1609	Transcriptional regulator
HQ616_RS09330	COG3716	PTS system mannose fructose sorbose family IID component
HQ616_RS09335	COG3715	PTS system
HQ616_RS09340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS09345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HQ616_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
HQ616_RS09385	COG2176	DNA-directed DNA polymerase activity
HQ616_RS09390	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQ616_RS09390	COG1388	LysM domain
HQ616_RS09405	COG4589	Belongs to the CDS family
HQ616_RS09410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HQ616_RS09415	COG1862	Preprotein translocase
HQ616_RS09430	COG3493	citrate carrier protein
HQ616_RS09435	COG3290	protein histidine kinase activity
HQ616_RS09440	COG4565	transcriptional regulatory protein
HQ616_RS09445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HQ616_RS09455	COG3842	ATPase activity
HQ616_RS09525	COG1490	D-aminoacyl-tRNA deacylase activity
HQ616_RS09535	COG0737	Belongs to the 5'-nucleotidase family
HQ616_RS09545	COG1363	Peptidase, m42
HQ616_RS09560	COG4753	response regulator
HQ616_RS09560	COG2207	Transcriptional regulator
HQ616_RS09565	COG2972	Histidine kinase
HQ616_RS09570	COG3716	PTS system mannose fructose sorbose family IID component
HQ616_RS09575	COG3715	PTS system
HQ616_RS09615	COG3290	protein histidine kinase activity
HQ616_RS09620	COG3279	Response regulator of the LytR AlgR family
HQ616_RS09630	COG1263	PTS System
HQ616_RS09630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQ616_RS09630	COG2190	(PTS) system
HQ616_RS09635	COG5002	protein histidine kinase activity
HQ616_RS09640	COG0745	RESPONSE REGULATOR receiver
HQ616_RS09650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQ616_RS09655	COG0581	inorganic phosphate transmembrane transporter activity
HQ616_RS09660	COG0573	inorganic phosphate transmembrane transporter activity
HQ616_RS09675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQ616_RS09690	COG0789	Transcriptional regulator
HQ616_RS09725	COG0456	acetyltransferase
HQ616_RS09730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQ616_RS09825	COG1131	(ABC) transporter
HQ616_RS09835	COG1396	sequence-specific DNA binding
HQ616_RS09845	COG1694	Mazg nucleotide pyrophosphohydrolase
HQ616_RS09860	COG2897	thiosulfate sulfurtransferase activity
HQ616_RS09875	COG0371	Dehydrogenase
HQ616_RS09885	COG0646	methionine synthase
HQ616_RS09885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HQ616_RS09900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HQ616_RS09910	COG0745	RESPONSE REGULATOR receiver
HQ616_RS09915	COG2205	protein histidine kinase activity
HQ616_RS09915	COG2770	Histidine kinase
HQ616_RS09930	COG2814	Major facilitator Superfamily
HQ616_RS09935	COG4667	esterase of the alpha-beta hydrolase superfamily
HQ616_RS09960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQ616_RS09965	COG0564	pseudouridine synthase activity
HQ616_RS09985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HQ616_RS09990	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HQ616_RS10010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQ616_RS10015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HQ616_RS10015	COG1116	anion transmembrane transporter activity
HQ616_RS10020	COG4120	Belongs to the binding-protein-dependent transport system permease family
HQ616_RS10030	COG0561	phosphatase activity
HQ616_RS10035	COG2514	catechol 2,3-dioxygenase activity
HQ616_RS10045	COG0602	queuosine metabolic process
HQ616_RS10065	COG1328	CTP reductase activity
HQ616_RS10080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQ616_RS10090	COG1393	Belongs to the ArsC family
HQ616_RS10095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQ616_RS10105	COG2818	Glycosylase
HQ616_RS10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HQ616_RS10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HQ616_RS10175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQ616_RS10245	COG0745	RESPONSE REGULATOR receiver
HQ616_RS10250	COG5002	protein histidine kinase activity
HQ616_RS10255	COG1288	antiporter activity
HQ616_RS10265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQ616_RS10270	COG3852	Histidine kinase
HQ616_RS10275	COG0784	Response regulator, receiver
HQ616_RS10280	COG0517	IMP dehydrogenase activity
HQ616_RS10280	COG1125	glycine betaine transport
HQ616_RS10285	COG1174	glycine betaine transport
HQ616_RS10290	COG0392	lysyltransferase activity
HQ616_RS10290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQ616_RS10300	COG3759	membrane
HQ616_RS10430	COG0582	viral genome integration into host DNA
HQ616_RS10445	COG0305	Participates in initiation and elongation during chromosome replication
HQ616_RS10465	COG2095	MarC family integral membrane protein
HQ616_RS10470	COG0482	sulfurtransferase activity
HQ616_RS10475	COG1760	l-serine dehydratase
HQ616_RS10480	COG1760	l-serine dehydratase
HQ616_RS10485	COG0741	lytic transglycosylase activity
HQ616_RS10510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQ616_RS10515	COG0612	Peptidase, M16
HQ616_RS10520	COG0612	Peptidase, M16
HQ616_RS10525	COG2501	S4 domain
HQ616_RS10545	COG0516	GMP reductase activity
HQ616_RS10545	COG0517	IMP dehydrogenase activity
HQ616_RS10555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQ616_RS10570	COG0454	-acetyltransferase
HQ616_RS10585	COG0549	Belongs to the carbamate kinase family
HQ616_RS10600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HQ616_RS10605	COG0488	(ABC) transporter
HQ616_RS10610	COG4485	Bacterial membrane protein, YfhO
HQ616_RS10630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQ616_RS10635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQ616_RS10640	COG1475	DNA binding
HQ616_RS10650	COG3590	peptidase
HQ616_RS10655	COG3590	peptidase