locus-tag	class	description
GBS85147_RS00010	COG0592	DNA-directed DNA polymerase activity
GBS85147_RS00015	COG1597	lipid kinase activity
GBS85147_RS00025	COG0012	GTP binding
GBS85147_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GBS85147_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GBS85147_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBS85147_RS00170	COG0436	Aminotransferase
GBS85147_RS00185	COG0416	fatty acid biosynthetic process
GBS85147_RS00190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBS85147_RS00195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GBS85147_RS00200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBS85147_RS00215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GBS85147_RS00220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GBS85147_RS00255	COG1175	transmembrane transport
GBS85147_RS00260	COG0395	ABC-type sugar transport system, permease component
GBS85147_RS00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBS85147_RS00285	COG3458	cephalosporin-C deacetylase activity
GBS85147_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GBS85147_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBS85147_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBS85147_RS00345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GBS85147_RS00345	COG2755	lipolytic protein G-D-S-L family
GBS85147_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
GBS85147_RS00350	COG1454	alcohol dehydrogenase
GBS85147_RS00355	COG1064	alcohol dehydrogenase
GBS85147_RS00365	COG0534	Mate efflux family protein
GBS85147_RS00475	COG0201	protein transport
GBS85147_RS00480	COG0563	adenylate kinase activity
GBS85147_RS00490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBS85147_RS00500	COG0202	RNA polymerase activity
GBS85147_RS00620	COG1705	Flagellar rod assembly protein muramidase FlgJ
GBS85147_RS00635	COG0443	Heat shock 70 kDa protein
GBS85147_RS00645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBS85147_RS00655	COG0351	phosphomethylpyrimidine kinase
GBS85147_RS00660	COG4720	Psort location CytoplasmicMembrane, score
GBS85147_RS00670	COG0668	transmembrane transport
GBS85147_RS00700	COG0756	dUTP diphosphatase activity
GBS85147_RS00715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBS85147_RS00720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBS85147_RS00725	COG1879	ABC-type sugar transport system periplasmic component
GBS85147_RS00730	COG1172	Belongs to the binding-protein-dependent transport system permease family
GBS85147_RS00745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBS85147_RS00750	COG1609	Transcriptional regulator
GBS85147_RS00755	COG0577	efflux transmembrane transporter activity
GBS85147_RS00760	COG1136	(ABC) transporter
GBS85147_RS00765	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS00770	COG5002	protein histidine kinase activity
GBS85147_RS00785	COG0191	fructose-bisphosphate aldolase activity
GBS85147_RS00805	COG1461	Dihydroxyacetone kinase
GBS85147_RS00825	COG1126	abc transporter atp-binding protein
GBS85147_RS00830	COG0765	amino acid transport
GBS85147_RS00850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GBS85147_RS00860	COG0719	Fe-S assembly protein
GBS85147_RS00865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBS85147_RS00875	COG0719	Fe-S assembly protein
GBS85147_RS00880	COG1686	Belongs to the peptidase S11 family
GBS85147_RS00885	COG1686	Belongs to the peptidase S11 family
GBS85147_RS00890	COG4166	transmembrane transport
GBS85147_RS00895	COG0601	transmembrane transport
GBS85147_RS00900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBS85147_RS00905	COG0444	Belongs to the ABC transporter superfamily
GBS85147_RS00910	COG4608	Belongs to the ABC transporter superfamily
GBS85147_RS00950	COG1121	(ABC) transporter
GBS85147_RS00955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GBS85147_RS00965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBS85147_RS00970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBS85147_RS00970	COG4499	WXG100 protein secretion system (Wss), protein YukC
GBS85147_RS00990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GBS85147_RS00995	COG1459	type II secretion system
GBS85147_RS01050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBS85147_RS01055	COG1363	Peptidase, m42
GBS85147_RS01070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GBS85147_RS01075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBS85147_RS01090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBS85147_RS01110	COG1346	cytolysis
GBS85147_RS01120	COG0601	transmembrane transport
GBS85147_RS01130	COG1122	ATPase activity
GBS85147_RS01140	COG1263	PTS System
GBS85147_RS01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS01145	COG0366	Alpha amylase catalytic
GBS85147_RS01150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBS85147_RS01165	COG3959	Transketolase, thiamine diphosphate binding domain
GBS85147_RS01170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GBS85147_RS01175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GBS85147_RS01195	COG1045	serine acetyltransferase
GBS85147_RS01205	COG0215	cysteine-tRNA ligase activity
GBS85147_RS01210	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GBS85147_RS01230	COG1476	TRANSCRIPTIONal
GBS85147_RS01235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBS85147_RS01285	COG1396	sequence-specific DNA binding
GBS85147_RS01290	COG2814	Major facilitator Superfamily
GBS85147_RS01300	COG1732	Glycine betaine
GBS85147_RS01430	COG0519	Catalyzes the synthesis of GMP from XMP
GBS85147_RS01475	COG1695	Transcriptional regulator
GBS85147_RS01490	COG1755	Isoprenylcysteine carboxyl methyltransferase
GBS85147_RS01530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GBS85147_RS01535	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBS85147_RS01555	COG1131	(ABC) transporter
GBS85147_RS01565	COG2190	(PTS) system
GBS85147_RS01565	COG1263	PTS System
GBS85147_RS01565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS01570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBS85147_RS01580	COG0275	rRNA processing
GBS85147_RS01590	COG0768	penicillin binding
GBS85147_RS01615	COG1126	abc transporter atp-binding protein
GBS85147_RS01625	COG0492	ferredoxin-NADP+ reductase activity
GBS85147_RS01630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GBS85147_RS01640	COG3579	cysteine-type endopeptidase activity
GBS85147_RS01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBS85147_RS01665	COG0116	Belongs to the methyltransferase superfamily
GBS85147_RS01675	COG1854	S-ribosylhomocysteine lyase activity
GBS85147_RS01680	COG1418	mRNA catabolic process
GBS85147_RS01680	COG4372	Transposase
GBS85147_RS01685	COG1131	(ABC) transporter
GBS85147_RS01695	COG4585	Histidine kinase
GBS85147_RS01700	COG2197	response regulator
GBS85147_RS01710	COG0194	GDP metabolic process
GBS85147_RS01720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBS85147_RS01725	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBS85147_RS01730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBS85147_RS01730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBS85147_RS01740	COG2815	serine threonine protein kinase
GBS85147_RS01740	COG0515	serine threonine protein kinase
GBS85147_RS01750	COG4585	Histidine kinase
GBS85147_RS01755	COG2197	response regulator
GBS85147_RS01765	COG1098	S1 RNA binding domain
GBS85147_RS01770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBS85147_RS01775	COG1349	DNA-binding transcription factor activity
GBS85147_RS01785	COG1447	Phosphotransferase system cellobiose-specific component IIA
GBS85147_RS01795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GBS85147_RS01800	COG1882	Formate acetyltransferase
GBS85147_RS01820	COG1739	Uncharacterized protein family UPF0029
GBS85147_RS01825	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GBS85147_RS01830	COG1040	competence protein
GBS85147_RS01865	COG0527	aspartate kinase activity
GBS85147_RS01870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBS85147_RS01875	COG1024	Enoyl-CoA hydratase
GBS85147_RS01885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBS85147_RS01895	COG2070	2-Nitropropane dioxygenase
GBS85147_RS01900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GBS85147_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
GBS85147_RS01910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBS85147_RS01925	COG0439	Biotin carboxylase
GBS85147_RS01945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBS85147_RS01960	COG3716	PTS system mannose fructose sorbose family IID component
GBS85147_RS01965	COG3715	PTS system
GBS85147_RS01975	COG0561	phosphatase activity
GBS85147_RS01990	COG2252	PERMEase
GBS85147_RS01995	COG0802	atpase or kinase
GBS85147_RS02005	COG1316	TRANSCRIPTIONal
GBS85147_RS02015	COG0537	adenosine 5'-monophosphoramidase activity
GBS85147_RS02030	COG1131	(ABC) transporter
GBS85147_RS02035	COG4473	ABC transporter
GBS85147_RS02045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GBS85147_RS02060	COG0195	Participates in both transcription termination and antitermination
GBS85147_RS02065	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GBS85147_RS02075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GBS85147_RS02080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GBS85147_RS02105	COG2860	membrane
GBS85147_RS02115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBS85147_RS02115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBS85147_RS02120	COG1832	CoA-binding protein
GBS85147_RS02140	COG5002	protein histidine kinase activity
GBS85147_RS02160	COG1268	BioY protein
GBS85147_RS02165	COG1234	tRNA 3'-trailer cleavage
GBS85147_RS02180	COG0166	Belongs to the GPI family
GBS85147_RS02185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBS85147_RS02190	COG0457	Tetratricopeptide repeat
GBS85147_RS02190	COG0705	Rhomboid family
GBS85147_RS02195	COG1744	ABC transporter substrate-binding protein PnrA-like
GBS85147_RS02200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GBS85147_RS02215	COG0706	membrane insertase activity
GBS85147_RS02275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBS85147_RS02285	COG2153	protein acetylation
GBS85147_RS02295	COG1216	Glycosyl transferase, family 2
GBS85147_RS02295	COG1442	glycosyl transferase family 8
GBS85147_RS02335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBS85147_RS02345	COG0789	Transcriptional regulator
GBS85147_RS02350	COG1063	alcohol dehydrogenase
GBS85147_RS02355	COG0656	L-ascorbic acid biosynthetic process
GBS85147_RS02395	COG2226	methyltransferase
GBS85147_RS02405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBS85147_RS02410	COG3414	Phosphotransferase system galactitol-specific IIB component
GBS85147_RS02415	COG3775	system Galactitol-specific IIC component
GBS85147_RS02420	COG0235	Class ii aldolase
GBS85147_RS02430	COG3775	system Galactitol-specific IIC component
GBS85147_RS02435	COG3414	Phosphotransferase system galactitol-specific IIB component
GBS85147_RS02440	COG2207	Transcriptional regulator
GBS85147_RS02450	COG1175	transmembrane transport
GBS85147_RS02455	COG0395	ABC-type sugar transport system, permease component
GBS85147_RS02465	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GBS85147_RS02475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GBS85147_RS02480	COG2017	converts alpha-aldose to the beta-anomer
GBS85147_RS02520	COG0673	inositol 2-dehydrogenase activity
GBS85147_RS02530	COG2315	Protein conserved in bacteria
GBS85147_RS02535	COG2502	aspartate--ammonia ligase
GBS85147_RS02545	COG0742	ribosomal rna small subunit methyltransferase
GBS85147_RS02560	COG3480	Lon protease (S16) C-terminal proteolytic domain
GBS85147_RS02565	COG0737	Belongs to the 5'-nucleotidase family
GBS85147_RS02570	COG4470	Protein conserved in bacteria
GBS85147_RS02585	COG1132	(ABC) transporter
GBS85147_RS02590	COG1132	(ABC) transporter
GBS85147_RS02595	COG0512	Glutamine amidotransferase of anthranilate synthase
GBS85147_RS02600	COG1268	BioY protein
GBS85147_RS02605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GBS85147_RS02625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GBS85147_RS02640	COG1940	carbohydrate kinase activity
GBS85147_RS02645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GBS85147_RS02650	COG1217	gtp-binding protein TYPA
GBS85147_RS02685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GBS85147_RS02695	COG0762	integral membrane protein
GBS85147_RS02700	COG2302	S4 RNA-binding domain
GBS85147_RS02705	COG3599	regulation of cell shape
GBS85147_RS02710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBS85147_RS02720	COG0494	nUDIX hydrolase
GBS85147_RS02725	COG0542	response to heat
GBS85147_RS02730	COG4703	Protein of unknown function (DUF1797)
GBS85147_RS02735	COG0765	amino acid transport
GBS85147_RS02740	COG1126	abc transporter atp-binding protein
GBS85147_RS02745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBS85147_RS02755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GBS85147_RS02760	COG1570	exodeoxyribonuclease VII activity
GBS85147_RS02765	COG1722	exodeoxyribonuclease VII activity
GBS85147_RS02775	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GBS85147_RS02780	COG1438	arginine binding
GBS85147_RS02785	COG0497	DNA recombination
GBS85147_RS02790	COG1307	EDD domain protein, DegV family
GBS85147_RS02795	COG2755	lipolytic protein G-D-S-L family
GBS85147_RS02840	COG1078	dGTPase activity
GBS85147_RS02865	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GBS85147_RS02875	COG2884	Cell division ATP-binding protein ftsE
GBS85147_RS02880	COG2177	Part of the ABC transporter FtsEX involved in
GBS85147_RS02900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GBS85147_RS02900	COG1199	ATP-dependent helicase activity
GBS85147_RS02905	COG0436	Aminotransferase
GBS85147_RS02910	COG0017	Asparaginyl-tRNA synthetase
GBS85147_RS02930	COG1660	Displays ATPase and GTPase activities
GBS85147_RS02955	COG0254	rRNA binding
GBS85147_RS02960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GBS85147_RS02965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBS85147_RS02970	COG0716	FMN binding
GBS85147_RS02975	COG1605	Chorismate mutase
GBS85147_RS02975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GBS85147_RS02980	COG0038	chloride channel
GBS85147_RS02985	COG0335	large ribosomal subunit rRNA binding
GBS85147_RS02995	COG0772	Belongs to the SEDS family
GBS85147_RS03015	COG0560	Phosphoserine phosphatase
GBS85147_RS03030	COG0148	phosphopyruvate hydratase activity
GBS85147_RS03135	COG1316	TRANSCRIPTIONal
GBS85147_RS03185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBS85147_RS03190	COG4555	ABC transporter
GBS85147_RS03225	COG0424	maF-like protein
GBS85147_RS03230	COG1011	Hydrolase
GBS85147_RS03240	COG0642	Histidine kinase
GBS85147_RS03245	COG5002	protein histidine kinase activity
GBS85147_RS03260	COG1028	Short-chain dehydrogenase reductase Sdr
GBS85147_RS03265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBS85147_RS03270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GBS85147_RS03290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GBS85147_RS03295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GBS85147_RS03325	COG3590	peptidase
GBS85147_RS03350	COG1136	(ABC) transporter
GBS85147_RS03365	COG0586	Pfam SNARE associated Golgi protein
GBS85147_RS03370	COG4619	ABC transporter
GBS85147_RS03375	COG0390	transport system, permease component
GBS85147_RS03385	COG0583	DNA-binding transcription factor activity
GBS85147_RS03395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBS85147_RS03400	COG2211	Major facilitator Superfamily
GBS85147_RS03410	COG3250	beta-galactosidase activity
GBS85147_RS03415	COG2186	Transcriptional regulator
GBS85147_RS03420	COG0800	Aldolase
GBS85147_RS03425	COG1904	glucuronate isomerase
GBS85147_RS03430	COG1312	Catalyzes the dehydration of D-mannonate
GBS85147_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
GBS85147_RS03455	COG1609	Transcriptional regulator
GBS85147_RS03470	COG0438	transferase activity, transferring glycosyl groups
GBS85147_RS03495	COG0765	amino acid transport
GBS85147_RS03500	COG0765	amino acid transport
GBS85147_RS03505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBS85147_RS03510	COG1126	abc transporter atp-binding protein
GBS85147_RS03515	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS03520	COG5002	protein histidine kinase activity
GBS85147_RS03525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GBS85147_RS03530	COG2832	Protein of unknown function (DUF454)
GBS85147_RS03540	COG1196	nuclear chromosome segregation
GBS85147_RS03545	COG0561	phosphatase activity
GBS85147_RS03550	COG0561	phosphatase activity
GBS85147_RS03555	COG0552	protein localization to endoplasmic reticulum
GBS85147_RS03560	COG3689	TIGRFAM TIGR03943 family protein
GBS85147_RS03565	COG0701	Predicted permease
GBS85147_RS03580	COG2183	response to ionizing radiation
GBS85147_RS03585	COG3091	SprT-like family
GBS85147_RS03590	COG1983	PspC domain protein
GBS85147_RS03625	COG0826	peptidase U32
GBS85147_RS03630	COG4443	Transcriptional Coactivator p15 (PC4)
GBS85147_RS03640	COG1914	H( )-stimulated, divalent metal cation uptake system
GBS85147_RS03655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBS85147_RS03655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBS85147_RS03680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBS85147_RS03705	COG1164	Oligoendopeptidase f
GBS85147_RS03715	COG0772	Belongs to the SEDS family
GBS85147_RS03735	COG0768	penicillin binding
GBS85147_RS03750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GBS85147_RS03755	COG2223	nitrite transmembrane transporter activity
GBS85147_RS03780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBS85147_RS03785	COG2011	ABC-type metal ion transport system permease component
GBS85147_RS03790	COG1464	Belongs to the NlpA lipoprotein family
GBS85147_RS03795	COG0513	Belongs to the DEAD box helicase family
GBS85147_RS03805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GBS85147_RS03810	COG0204	Acyl-transferase
GBS85147_RS03815	COG1555	photosystem II stabilization
GBS85147_RS03815	COG1596	polysaccharide export
GBS85147_RS03820	COG0658	competence protein
GBS85147_RS03820	COG2333	competence protein COMEC
GBS85147_RS03825	COG0561	phosphatase activity
GBS85147_RS03830	COG1609	Transcriptional regulator
GBS85147_RS03835	COG0657	acetylesterase activity
GBS85147_RS03850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GBS85147_RS03855	COG3711	transcriptional antiterminator
GBS85147_RS03860	COG1263	PTS System
GBS85147_RS03860	COG2190	(PTS) system
GBS85147_RS03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS03870	COG3835	regulator
GBS85147_RS03875	COG1929	Belongs to the glycerate kinase type-1 family
GBS85147_RS03880	COG2610	gluconate transmembrane transporter activity
GBS85147_RS03890	COG1846	Transcriptional regulator
GBS85147_RS03895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GBS85147_RS03905	COG0363	glucosamine-6-phosphate deaminase activity
GBS85147_RS03910	COG0435	Glutathione S-transferase
GBS85147_RS03915	COG1187	pseudouridine synthase activity
GBS85147_RS03935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GBS85147_RS03940	COG4122	O-methyltransferase activity
GBS85147_RS03950	COG4894	glucomannan catabolic process
GBS85147_RS03965	COG1442	glycosyl transferase family 8
GBS85147_RS03980	COG1476	TRANSCRIPTIONal
GBS85147_RS03995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBS85147_RS04000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBS85147_RS04005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GBS85147_RS04020	COG1012	belongs to the aldehyde dehydrogenase family
GBS85147_RS04025	COG0726	polysaccharide deacetylase
GBS85147_RS04030	COG0513	Belongs to the DEAD box helicase family
GBS85147_RS04040	COG1956	GAF domain-containing protein
GBS85147_RS04045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBS85147_RS04055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GBS85147_RS04055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GBS85147_RS04060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBS85147_RS04085	COG4721	ABC-type cobalt transport system, permease component
GBS85147_RS04090	COG1122	ATPase activity
GBS85147_RS04100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GBS85147_RS04120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBS85147_RS04130	COG4109	DRTGG domain
GBS85147_RS04135	COG0024	Methionine aminopeptidase
GBS85147_RS04145	COG2246	polysaccharide biosynthetic process
GBS85147_RS04150	COG4708	membrane
GBS85147_RS04155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBS85147_RS04160	COG1597	lipid kinase activity
GBS85147_RS04165	COG1523	belongs to the glycosyl hydrolase 13 family
GBS85147_RS04175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBS85147_RS04180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBS85147_RS04185	COG0297	glycogen (starch) synthase activity
GBS85147_RS04225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GBS85147_RS04260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBS85147_RS04260	COG0072	phenylalanine-tRNA ligase activity
GBS85147_RS04265	COG2321	neutral zinc metallopeptidase
GBS85147_RS04275	COG1074	ATP-dependent DNA helicase activity
GBS85147_RS04285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GBS85147_RS04290	COG0488	(ABC) transporter
GBS85147_RS04295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GBS85147_RS04300	COG0022	dehydrogenase e1 component
GBS85147_RS04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBS85147_RS04305	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBS85147_RS04315	COG0095	Lipoate-protein ligase
GBS85147_RS04320	COG3442	glutamine amidotransferase
GBS85147_RS04325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GBS85147_RS04330	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GBS85147_RS04355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GBS85147_RS04365	COG0647	UMP catabolic process
GBS85147_RS04375	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GBS85147_RS04380	COG1518	maintenance of DNA repeat elements
GBS85147_RS04385	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GBS85147_RS04400	COG0481	GTPase activity
GBS85147_RS04410	COG1418	mRNA catabolic process
GBS85147_RS04415	COG0456	acetyltransferase
GBS85147_RS04425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GBS85147_RS04450	COG1131	(ABC) transporter
GBS85147_RS04455	COG1725	Transcriptional regulator
GBS85147_RS04465	COG0205	6-phosphofructokinase activity
GBS85147_RS04470	COG0469	pyruvate kinase activity
GBS85147_RS04480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBS85147_RS04485	COG2824	Alkylphosphonate utilization operon protein PhnA
GBS85147_RS04490	COG0765	amino acid transport
GBS85147_RS04495	COG1126	abc transporter atp-binding protein
GBS85147_RS04510	COG1072	(Pantothenic acid kinase))
GBS85147_RS04515	COG2813	Specifically methylates the guanine in position
GBS85147_RS04525	COG1744	ABC transporter substrate-binding protein PnrA-like
GBS85147_RS04530	COG3845	ABC transporter
GBS85147_RS04535	COG4603	Belongs to the binding-protein-dependent transport system permease family
GBS85147_RS04540	COG1079	Belongs to the binding-protein-dependent transport system permease family
GBS85147_RS04560	COG3764	Sortase (surface protein transpeptidase)
GBS85147_RS04565	COG0346	lactoylglutathione lyase activity
GBS85147_RS04585	COG2188	Transcriptional regulator
GBS85147_RS04590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GBS85147_RS04600	COG1464	Belongs to the NlpA lipoprotein family
GBS85147_RS04615	COG1136	(ABC) transporter
GBS85147_RS04625	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS04630	COG5002	protein histidine kinase activity
GBS85147_RS04635	COG4974	Belongs to the 'phage' integrase family
GBS85147_RS04640	COG4166	transmembrane transport
GBS85147_RS04655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GBS85147_RS04660	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GBS85147_RS04665	COG5002	protein histidine kinase activity
GBS85147_RS04670	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS04680	COG0704	Plays a role in the regulation of phosphate uptake
GBS85147_RS04685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GBS85147_RS04690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GBS85147_RS04695	COG0581	inorganic phosphate transmembrane transporter activity
GBS85147_RS04700	COG0573	inorganic phosphate transmembrane transporter activity
GBS85147_RS04710	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GBS85147_RS04710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBS85147_RS04715	COG0483	inositol monophosphate 1-phosphatase activity
GBS85147_RS04720	COG4476	Belongs to the UPF0223 family
GBS85147_RS04730	COG0196	riboflavin kinase activity
GBS85147_RS04735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBS85147_RS04765	COG1136	(ABC) transporter
GBS85147_RS04770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBS85147_RS04775	COG0758	DNA mediated transformation
GBS85147_RS04780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GBS85147_RS04785	COG4604	ABC transporter, ATP-binding protein
GBS85147_RS04790	COG4605	iron ion homeostasis
GBS85147_RS04795	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBS85147_RS04800	COG0110	maltose O-acetyltransferase activity
GBS85147_RS04810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GBS85147_RS04815	COG1376	ErfK ybiS ycfS ynhG family protein
GBS85147_RS04820	COG1966	Carbon starvation protein
GBS85147_RS04825	COG3279	Response regulator of the LytR AlgR family
GBS85147_RS04830	COG3275	phosphorelay sensor kinase activity
GBS85147_RS04865	COG3942	CHAP domain
GBS85147_RS04865	COG1705	Flagellar rod assembly protein muramidase FlgJ
GBS85147_RS05040	COG0505	Belongs to the CarA family
GBS85147_RS05070	COG0488	(ABC) transporter
GBS85147_RS05080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GBS85147_RS05090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBS85147_RS05140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GBS85147_RS05145	COG4684	Psort location CytoplasmicMembrane, score
GBS85147_RS05150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBS85147_RS05160	COG1132	(ABC) transporter
GBS85147_RS05190	COG2890	protein-(glutamine-N5) methyltransferase activity
GBS85147_RS05205	COG1942	4-Oxalocrotonate Tautomerase
GBS85147_RS05220	COG3976	FMN-binding domain protein
GBS85147_RS05220	COG1053	succinate dehydrogenase
GBS85147_RS05220	COG0431	NADPH-dependent FMN reductase
GBS85147_RS05230	COG2233	PERMEase
GBS85147_RS05245	COG0477	Major facilitator Superfamily
GBS85147_RS05260	COG4221	oxidoreductase activity
GBS85147_RS05265	COG0280	phosphate acetyltransferase
GBS85147_RS05270	COG0564	pseudouridine synthase activity
GBS85147_RS05280	COG2357	RelA SpoT domain protein
GBS85147_RS05295	COG1104	cysteine desulfurase activity
GBS85147_RS05315	COG0628	permease
GBS85147_RS05320	COG2723	6-phospho-beta-galactosidase activity
GBS85147_RS05330	COG0561	phosphatase activity
GBS85147_RS05340	COG0038	chloride channel
GBS85147_RS05350	COG1177	transmembrane transport
GBS85147_RS05355	COG1176	ABC-type spermidine putrescine transport system, permease component I
GBS85147_RS05365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GBS85147_RS05370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GBS85147_RS05390	COG0285	dihydrofolate synthase activity
GBS85147_RS05395	COG2962	Rard protein
GBS85147_RS05410	COG0726	polysaccharide deacetylase
GBS85147_RS05415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GBS85147_RS05420	COG1012	belongs to the aldehyde dehydrogenase family
GBS85147_RS05495	COG2261	transglycosylase associated protein
GBS85147_RS05520	COG1115	amino acid carrier protein
GBS85147_RS05525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBS85147_RS05535	COG1346	cytolysis
GBS85147_RS05550	COG0539	negative regulation of cytoplasmic translation
GBS85147_RS05570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GBS85147_RS05580	COG0187	DNA topoisomerase II activity
GBS85147_RS05585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GBS85147_RS05590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBS85147_RS05600	COG2755	lipolytic protein G-D-S-L family
GBS85147_RS05600	COG1083	cytidylyl-transferase
GBS85147_RS05615	COG2089	acid synthase
GBS85147_RS05630	COG1216	Glycosyl transferase, family 2
GBS85147_RS05630	COG1442	glycosyl transferase family 8
GBS85147_RS05635	COG1216	Glycosyl transferase, family 2
GBS85147_RS05635	COG1442	glycosyl transferase family 8
GBS85147_RS05650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBS85147_RS05660	COG0489	protein tyrosine kinase activity
GBS85147_RS05675	COG1316	TRANSCRIPTIONal
GBS85147_RS05700	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GBS85147_RS05735	COG3842	ATPase activity
GBS85147_RS05750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GBS85147_RS05755	COG3527	Alpha-acetolactate decarboxylase
GBS85147_RS05760	COG0028	Belongs to the TPP enzyme family
GBS85147_RS05765	COG0457	Tetratricopeptide repeat
GBS85147_RS05770	COG0628	permease
GBS85147_RS05780	COG1051	belongs to the nudix hydrolase family
GBS85147_RS05785	COG5492	domain, Protein
GBS85147_RS05790	COG1088	dTDP-glucose 4,6-dehydratase activity
GBS85147_RS05800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GBS85147_RS05805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBS85147_RS05815	COG2384	SAM-dependent methyltransferase
GBS85147_RS05835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GBS85147_RS05835	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GBS85147_RS05840	COG0300	oxidoreductase activity
GBS85147_RS05855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBS85147_RS05885	COG1573	uracil-dna glycosylase
GBS85147_RS05890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBS85147_RS05900	COG0584	glycerophosphoryl diester phosphodiesterase
GBS85147_RS05915	COG0534	Mate efflux family protein
GBS85147_RS05945	COG4974	Belongs to the 'phage' integrase family
GBS85147_RS05955	COG1396	sequence-specific DNA binding
GBS85147_RS05975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GBS85147_RS05975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GBS85147_RS05980	COG1447	Phosphotransferase system cellobiose-specific component IIA
GBS85147_RS06010	COG0347	Belongs to the P(II) protein family
GBS85147_RS06015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBS85147_RS06020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBS85147_RS06020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBS85147_RS06020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBS85147_RS06025	COG1105	Belongs to the carbohydrate kinase PfkB family
GBS85147_RS06030	COG1737	Transcriptional regulator
GBS85147_RS06045	COG3843	relaxase mobilization nuclease domain protein
GBS85147_RS06065	COG4581	dead DEAH box helicase
GBS85147_RS06075	COG0542	response to heat
GBS85147_RS06080	COG1396	sequence-specific DNA binding
GBS85147_RS06120	COG1131	(ABC) transporter
GBS85147_RS06135	COG0602	queuosine metabolic process
GBS85147_RS06255	COG0270	DNA (cytosine-5-)-methyltransferase activity
GBS85147_RS06280	COG2040	homocysteine
GBS85147_RS06285	COG0833	amino acid
GBS85147_RS06320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GBS85147_RS06330	COG3425	synthase
GBS85147_RS06345	COG1272	protein, Hemolysin III
GBS85147_RS06390	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS06395	COG2357	RelA SpoT domain protein
GBS85147_RS06400	COG1132	(ABC) transporter
GBS85147_RS06415	COG0737	Belongs to the 5'-nucleotidase family
GBS85147_RS06420	COG0242	peptide deformylase activity
GBS85147_RS06425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GBS85147_RS06435	COG1132	(ABC) transporter
GBS85147_RS06450	COG0488	(ABC) transporter
GBS85147_RS06480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBS85147_RS06480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBS85147_RS06480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBS85147_RS06485	COG1105	Belongs to the carbohydrate kinase PfkB family
GBS85147_RS06490	COG1349	DNA-binding transcription factor activity
GBS85147_RS06495	COG1705	Flagellar rod assembly protein muramidase FlgJ
GBS85147_RS06495	COG1388	LysM domain
GBS85147_RS06545	COG1837	Belongs to the UPF0109 family
GBS85147_RS06550	COG0228	four-way junction DNA binding
GBS85147_RS06555	COG0577	efflux transmembrane transporter activity
GBS85147_RS06560	COG1136	(ABC) transporter
GBS85147_RS06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBS85147_RS06575	COG0505	Belongs to the CarA family
GBS85147_RS06585	COG0564	pseudouridine synthase activity
GBS85147_RS06595	COG0583	DNA-binding transcription factor activity
GBS85147_RS06600	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GBS85147_RS06620	COG0301	tRNA thio-modification
GBS85147_RS06625	COG1104	cysteine desulfurase activity
GBS85147_RS06635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBS85147_RS06660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GBS85147_RS06665	COG1368	sulfuric ester hydrolase activity
GBS85147_RS06670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GBS85147_RS06680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GBS85147_RS06710	COG2244	polysaccharide biosynthetic process
GBS85147_RS06715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBS85147_RS06720	COG1120	ATPase activity
GBS85147_RS06725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GBS85147_RS06730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBS85147_RS06735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBS85147_RS06750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBS85147_RS06755	COG1253	flavin adenine dinucleotide binding
GBS85147_RS06760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GBS85147_RS06765	COG1242	4 iron, 4 sulfur cluster binding
GBS85147_RS06770	COG0671	phosphoesterase, PA-phosphatase related
GBS85147_RS06775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GBS85147_RS06805	COG0681	Belongs to the peptidase S26 family
GBS85147_RS06815	COG0297	glycogen (starch) synthase activity
GBS85147_RS06855	COG3475	LICD family
GBS85147_RS06870	COG0463	Glycosyl transferase, family 2
GBS85147_RS06875	COG1215	transferase activity, transferring glycosyl groups
GBS85147_RS06885	COG1091	dTDP-4-dehydrorhamnose reductase activity
GBS85147_RS06890	COG2151	metal-sulfur cluster biosynthetic enzyme
GBS85147_RS06895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBS85147_RS06900	COG0358	DNA primase activity
GBS85147_RS06905	COG1970	mechanosensitive ion channel activity
GBS85147_RS06920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBS85147_RS06925	COG0004	ammonium transporteR
GBS85147_RS06935	COG1054	Belongs to the UPF0176 family
GBS85147_RS06945	COG2271	Major facilitator Superfamily
GBS85147_RS06950	COG0058	SHG alpha-glucan phosphorylase activity
GBS85147_RS06955	COG1640	4-alpha-glucanotransferase
GBS85147_RS06960	COG1609	Transcriptional regulator
GBS85147_RS06970	COG1175	transmembrane transport
GBS85147_RS06975	COG3833	ABC-type maltose transport systems, permease component
GBS85147_RS06980	COG3104	oligopeptide transport
GBS85147_RS07000	COG0438	transferase activity, transferring glycosyl groups
GBS85147_RS07005	COG0653	protein targeting
GBS85147_RS07025	COG0201	protein transport
GBS85147_RS07030	COG1442	glycosyl transferase family 8
GBS85147_RS07035	COG1216	Glycosyl transferase, family 2
GBS85147_RS07035	COG1442	glycosyl transferase family 8
GBS85147_RS07040	COG1442	glycosyl transferase family 8
GBS85147_RS07045	COG1442	glycosyl transferase family 8
GBS85147_RS07050	COG1442	glycosyl transferase family 8
GBS85147_RS07080	COG0765	amino acid transport
GBS85147_RS07085	COG1126	abc transporter atp-binding protein
GBS85147_RS07110	COG2309	aminopeptidase activity
GBS85147_RS07125	COG1187	pseudouridine synthase activity
GBS85147_RS07130	COG0656	L-ascorbic acid biosynthetic process
GBS85147_RS07135	COG0778	Nitroreductase
GBS85147_RS07140	COG0346	lactoylglutathione lyase activity
GBS85147_RS07145	COG0463	Glycosyl transferase, family 2
GBS85147_RS07150	COG1113	amino acid transport
GBS85147_RS07155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GBS85147_RS07160	COG0557	exoribonuclease II activity
GBS85147_RS07170	COG2814	Major facilitator Superfamily
GBS85147_RS07180	COG1131	(ABC) transporter
GBS85147_RS07190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GBS85147_RS07235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GBS85147_RS07240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBS85147_RS07260	COG1702	phosphate starvation-inducible protein PhoH
GBS85147_RS07285	COG0233	cytoplasmic translational termination
GBS85147_RS07300	COG0444	Belongs to the ABC transporter superfamily
GBS85147_RS07305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBS85147_RS07310	COG0601	transmembrane transport
GBS85147_RS07315	COG0747	negative chemotaxis
GBS85147_RS07320	COG0081	regulation of translation
GBS85147_RS07325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBS85147_RS07335	COG1473	amidohydrolase
GBS85147_RS07340	COG0583	DNA-binding transcription factor activity
GBS85147_RS07350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBS85147_RS07355	COG1674	ftsk spoiiie
GBS85147_RS07360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBS85147_RS07385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GBS85147_RS07415	COG0673	inositol 2-dehydrogenase activity
GBS85147_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
GBS85147_RS07475	COG1114	Component of the transport system for branched-chain amino acids
GBS85147_RS07480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBS85147_RS07480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBS85147_RS07495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GBS85147_RS07505	COG0708	Exodeoxyribonuclease III
GBS85147_RS07510	COG1393	Belongs to the ArsC family
GBS85147_RS07515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBS85147_RS07520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBS85147_RS07530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GBS85147_RS07550	COG0470	DNA polymerase III
GBS85147_RS07560	COG0517	IMP dehydrogenase activity
GBS85147_RS07580	COG0559	Belongs to the binding-protein-dependent transport system permease family
GBS85147_RS07600	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GBS85147_RS07605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GBS85147_RS07615	COG0531	amino acid
GBS85147_RS07620	COG0569	domain protein
GBS85147_RS07625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GBS85147_RS07635	COG1187	pseudouridine synthase activity
GBS85147_RS07670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GBS85147_RS07685	COG1827	regulation of RNA biosynthetic process
GBS85147_RS07700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBS85147_RS07705	COG1254	Belongs to the acylphosphatase family
GBS85147_RS07715	COG0765	amino acid transport
GBS85147_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBS85147_RS07735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBS85147_RS07755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GBS85147_RS07765	COG1484	DNA-dependent DNA replication
GBS85147_RS07780	COG5002	protein histidine kinase activity
GBS85147_RS07785	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS07795	COG0501	Belongs to the peptidase M48B family
GBS85147_RS07800	COG1704	LemA family
GBS85147_RS07805	COG0357	Ribosomal RNA small subunit methyltransferase G
GBS85147_RS07810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GBS85147_RS07815	COG0569	domain protein
GBS85147_RS07840	COG1114	Component of the transport system for branched-chain amino acids
GBS85147_RS07845	COG1063	alcohol dehydrogenase
GBS85147_RS07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GBS85147_RS07875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GBS85147_RS07880	COG0217	transcriptional regulatory protein
GBS85147_RS07885	COG2376	Dihydroxyacetone kinase
GBS85147_RS07895	COG2376	Dihydroxyacetone kinase
GBS85147_RS07900	COG1461	Dihydroxyacetone kinase
GBS85147_RS07905	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GBS85147_RS07910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GBS85147_RS07920	COG0789	Transcriptional regulator
GBS85147_RS07925	COG1323	Belongs to the UPF0348 family
GBS85147_RS07935	COG2226	methyltransferase
GBS85147_RS07940	COG0799	negative regulation of ribosome biogenesis
GBS85147_RS07950	COG1713	HD superfamily hydrolase involved in NAD metabolism
GBS85147_RS07955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GBS85147_RS07960	COG1534	Rna-binding protein
GBS85147_RS07965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GBS85147_RS07970	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GBS85147_RS07985	COG0154	amidase activity
GBS85147_RS07990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBS85147_RS07995	COG0574	Belongs to the PEP-utilizing enzyme family
GBS85147_RS07995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBS85147_RS08005	COG0517	IMP dehydrogenase activity
GBS85147_RS08015	COG1335	isochorismatase
GBS85147_RS08020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GBS85147_RS08025	COG0436	Aminotransferase
GBS85147_RS08030	COG0589	response to stress
GBS85147_RS08040	COG0252	asparaginase activity
GBS85147_RS08050	COG4989	oxidoreductase activity
GBS85147_RS08055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GBS85147_RS08060	COG1705	Flagellar rod assembly protein muramidase FlgJ
GBS85147_RS08060	COG3942	CHAP domain
GBS85147_RS08070	COG0736	holo-[acyl-carrier-protein] synthase activity
GBS85147_RS08075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBS85147_RS08085	COG1482	cell wall glycoprotein biosynthetic process
GBS85147_RS08090	COG1940	carbohydrate kinase activity
GBS85147_RS08095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS08095	COG1263	PTS System
GBS85147_RS08095	COG2190	(PTS) system
GBS85147_RS08100	COG1621	beta-fructofuranosidase activity
GBS85147_RS08105	COG1609	Transcriptional regulator
GBS85147_RS08110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBS85147_RS08120	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBS85147_RS08140	COG2131	deaminase
GBS85147_RS08145	COG0006	proline dipeptidase activity
GBS85147_RS08155	COG2814	Major facilitator Superfamily
GBS85147_RS08180	COG0629	single-stranded DNA binding
GBS85147_RS08185	COG0360	Binds together with S18 to 16S ribosomal RNA
GBS85147_RS08190	COG1194	a g-specific adenine glycosylase
GBS85147_RS08200	COG3118	belongs to the thioredoxin family
GBS85147_RS08225	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBS85147_RS08230	COG0681	Belongs to the peptidase S26 family
GBS85147_RS08235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GBS85147_RS08250	COG1882	Formate acetyltransferase
GBS85147_RS08255	COG3576	pyridoxamine 5-phosphate
GBS85147_RS08260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBS85147_RS08275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GBS85147_RS08285	COG2814	Major facilitator Superfamily
GBS85147_RS08290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBS85147_RS08305	COG0142	geranyltranstransferase activity
GBS85147_RS08310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GBS85147_RS08315	COG4988	ABC transporter
GBS85147_RS08320	COG1294	oxidase, subunit
GBS85147_RS08325	COG1271	oxidase subunit
GBS85147_RS08330	COG1252	NADH dehydrogenase
GBS85147_RS08345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GBS85147_RS08360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBS85147_RS08365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GBS85147_RS08385	COG2081	HI0933 family
GBS85147_RS08410	COG0456	acetyltransferase
GBS85147_RS08415	COG1214	PFAM Peptidase M22, glycoprotease
GBS85147_RS08430	COG3942	CHAP domain
GBS85147_RS08435	COG0174	glutamine synthetase
GBS85147_RS08440	COG0789	Transcriptional regulator
GBS85147_RS08455	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GBS85147_RS08480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBS85147_RS08505	COG1162	GTPase activity
GBS85147_RS08530	COG0084	hydrolase, TatD family'
GBS85147_RS08555	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GBS85147_RS08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBS85147_RS08565	COG1696	Membrane protein involved in D-alanine export
GBS85147_RS08580	COG5002	protein histidine kinase activity
GBS85147_RS08585	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS08595	COG3314	Sporulation integral membrane protein YlbJ
GBS85147_RS08605	COG4175	Glycine betaine
GBS85147_RS08605	COG3448	diguanylate cyclase activity
GBS85147_RS08610	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GBS85147_RS08630	COG1070	Carbohydrate kinase
GBS85147_RS08640	COG3775	system Galactitol-specific IIC component
GBS85147_RS08645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBS85147_RS08655	COG1609	Transcriptional regulator
GBS85147_RS08705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBS85147_RS08740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBS85147_RS08745	COG1428	Deoxynucleoside kinase
GBS85147_RS08755	COG0542	response to heat
GBS85147_RS08760	COG4463	regulation of RNA biosynthetic process
GBS85147_RS08770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GBS85147_RS08780	COG0450	alkyl hydroperoxide reductase
GBS85147_RS08795	COG0025	NhaP-type Na H and K H
GBS85147_RS08805	COG1619	proteins homologs of microcin C7 resistance protein MccF
GBS85147_RS08810	COG3590	peptidase
GBS85147_RS08835	COG1609	Transcriptional regulator
GBS85147_RS08845	COG3716	PTS system mannose fructose sorbose family IID component
GBS85147_RS08850	COG3715	PTS system
GBS85147_RS08855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS08860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GBS85147_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
GBS85147_RS08905	COG2176	DNA-directed DNA polymerase activity
GBS85147_RS08910	COG1388	LysM domain
GBS85147_RS08910	COG1705	Flagellar rod assembly protein muramidase FlgJ
GBS85147_RS08925	COG4589	Belongs to the CDS family
GBS85147_RS08930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBS85147_RS08935	COG1862	Preprotein translocase
GBS85147_RS08945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GBS85147_RS08955	COG3842	ATPase activity
GBS85147_RS09025	COG1490	D-aminoacyl-tRNA deacylase activity
GBS85147_RS09035	COG0737	Belongs to the 5'-nucleotidase family
GBS85147_RS09045	COG1363	Peptidase, m42
GBS85147_RS09065	COG2207	Transcriptional regulator
GBS85147_RS09065	COG4753	response regulator
GBS85147_RS09070	COG2972	Histidine kinase
GBS85147_RS09075	COG3716	PTS system mannose fructose sorbose family IID component
GBS85147_RS09080	COG3715	PTS system
GBS85147_RS09105	COG1131	(ABC) transporter
GBS85147_RS09115	COG3279	Response regulator of the LytR AlgR family
GBS85147_RS09125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GBS85147_RS09125	COG1263	PTS System
GBS85147_RS09125	COG2190	(PTS) system
GBS85147_RS09130	COG5002	protein histidine kinase activity
GBS85147_RS09145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GBS85147_RS09150	COG0581	inorganic phosphate transmembrane transporter activity
GBS85147_RS09155	COG0573	inorganic phosphate transmembrane transporter activity
GBS85147_RS09170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GBS85147_RS09185	COG0789	Transcriptional regulator
GBS85147_RS09220	COG0456	acetyltransferase
GBS85147_RS09225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GBS85147_RS09265	COG1131	(ABC) transporter
GBS85147_RS09275	COG1396	sequence-specific DNA binding
GBS85147_RS09285	COG1694	Mazg nucleotide pyrophosphohydrolase
GBS85147_RS09300	COG2897	thiosulfate sulfurtransferase activity
GBS85147_RS09315	COG0371	Dehydrogenase
GBS85147_RS09325	COG0646	methionine synthase
GBS85147_RS09325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GBS85147_RS09330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBS85147_RS09340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GBS85147_RS09350	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS09355	COG2205	protein histidine kinase activity
GBS85147_RS09355	COG2770	Histidine kinase
GBS85147_RS09370	COG2814	Major facilitator Superfamily
GBS85147_RS09375	COG4667	esterase of the alpha-beta hydrolase superfamily
GBS85147_RS09400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBS85147_RS09405	COG0564	pseudouridine synthase activity
GBS85147_RS09425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GBS85147_RS09430	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GBS85147_RS09450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GBS85147_RS09455	COG1116	anion transmembrane transporter activity
GBS85147_RS09455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBS85147_RS09460	COG4120	Belongs to the binding-protein-dependent transport system permease family
GBS85147_RS09470	COG0561	phosphatase activity
GBS85147_RS09475	COG2514	catechol 2,3-dioxygenase activity
GBS85147_RS09480	COG3022	response to hydroperoxide
GBS85147_RS09485	COG0602	queuosine metabolic process
GBS85147_RS09505	COG1328	CTP reductase activity
GBS85147_RS09525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBS85147_RS09535	COG1393	Belongs to the ArsC family
GBS85147_RS09540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBS85147_RS09550	COG2818	Glycosylase
GBS85147_RS09595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GBS85147_RS09600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GBS85147_RS09605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GBS85147_RS09610	COG0124	histidyl-tRNA synthetase
GBS85147_RS09620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GBS85147_RS09630	COG0745	RESPONSE REGULATOR receiver
GBS85147_RS09635	COG5002	protein histidine kinase activity
GBS85147_RS09640	COG1288	antiporter activity
GBS85147_RS09650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBS85147_RS09655	COG3852	Histidine kinase
GBS85147_RS09660	COG0784	Response regulator, receiver
GBS85147_RS09665	COG0517	IMP dehydrogenase activity
GBS85147_RS09665	COG1125	glycine betaine transport
GBS85147_RS09670	COG1174	glycine betaine transport
GBS85147_RS09675	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GBS85147_RS09675	COG0392	lysyltransferase activity
GBS85147_RS09685	COG3759	membrane
GBS85147_RS09715	COG0305	Participates in initiation and elongation during chromosome replication
GBS85147_RS09735	COG2095	MarC family integral membrane protein
GBS85147_RS09740	COG0482	sulfurtransferase activity
GBS85147_RS09745	COG1760	l-serine dehydratase
GBS85147_RS09750	COG1760	l-serine dehydratase
GBS85147_RS09755	COG0741	lytic transglycosylase activity
GBS85147_RS09780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBS85147_RS09785	COG0612	Peptidase, M16
GBS85147_RS09790	COG0612	Peptidase, M16
GBS85147_RS09795	COG2501	S4 domain
GBS85147_RS09815	COG0517	IMP dehydrogenase activity
GBS85147_RS09815	COG0516	GMP reductase activity
GBS85147_RS09825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBS85147_RS09840	COG0454	-acetyltransferase
GBS85147_RS09855	COG0549	Belongs to the carbamate kinase family
GBS85147_RS09870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GBS85147_RS09875	COG0488	(ABC) transporter
GBS85147_RS09880	COG4485	Bacterial membrane protein, YfhO
GBS85147_RS09900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GBS85147_RS09905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBS85147_RS09910	COG1475	DNA binding