locus-tag	class	description
A964_RS00010	COG0592	DNA-directed DNA polymerase activity
A964_RS00015	COG1597	lipid kinase activity
A964_RS00025	COG0012	GTP binding
A964_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A964_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A964_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A964_RS00255	COG0436	Aminotransferase
A964_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A964_RS00285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A964_RS00300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A964_RS00335	COG1175	transmembrane transport
A964_RS00340	COG0395	ABC-type sugar transport system, permease component
A964_RS00355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A964_RS00365	COG3458	cephalosporin-C deacetylase activity
A964_RS00380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A964_RS00395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A964_RS00410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A964_RS00420	COG2755	lipolytic protein G-D-S-L family
A964_RS00420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A964_RS00425	COG1454	alcohol dehydrogenase
A964_RS00425	COG1012	belongs to the aldehyde dehydrogenase family
A964_RS00430	COG1064	alcohol dehydrogenase
A964_RS00440	COG0534	Mate efflux family protein
A964_RS00550	COG0201	protein transport
A964_RS00565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A964_RS00575	COG0202	RNA polymerase activity
A964_RS00675	COG3344	reverse transcriptase
A964_RS00695	COG3344	reverse transcriptase
A964_RS00715	COG1705	Flagellar rod assembly protein muramidase FlgJ
A964_RS00730	COG0443	Heat shock 70 kDa protein
A964_RS00740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A964_RS00750	COG0351	phosphomethylpyrimidine kinase
A964_RS00755	COG4720	Psort location CytoplasmicMembrane, score
A964_RS00765	COG0668	transmembrane transport
A964_RS00795	COG0756	dUTP diphosphatase activity
A964_RS00810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A964_RS00825	COG1879	ABC-type sugar transport system periplasmic component
A964_RS00830	COG1172	Belongs to the binding-protein-dependent transport system permease family
A964_RS00845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A964_RS00850	COG1609	Transcriptional regulator
A964_RS00855	COG0577	efflux transmembrane transporter activity
A964_RS00860	COG1136	(ABC) transporter
A964_RS00865	COG0745	RESPONSE REGULATOR receiver
A964_RS00870	COG5002	protein histidine kinase activity
A964_RS00885	COG0191	fructose-bisphosphate aldolase activity
A964_RS00905	COG1461	Dihydroxyacetone kinase
A964_RS00935	COG1755	Isoprenylcysteine carboxyl methyltransferase
A964_RS00940	COG5002	protein histidine kinase activity
A964_RS00945	COG0745	RESPONSE REGULATOR receiver
A964_RS00960	COG1126	abc transporter atp-binding protein
A964_RS00965	COG0765	amino acid transport
A964_RS00985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A964_RS00995	COG0719	Fe-S assembly protein
A964_RS01000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A964_RS01010	COG0719	Fe-S assembly protein
A964_RS01015	COG1686	Belongs to the peptidase S11 family
A964_RS01020	COG1686	Belongs to the peptidase S11 family
A964_RS01025	COG4166	transmembrane transport
A964_RS01030	COG0601	transmembrane transport
A964_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A964_RS01040	COG0444	Belongs to the ABC transporter superfamily
A964_RS01045	COG4608	Belongs to the ABC transporter superfamily
A964_RS01085	COG1121	(ABC) transporter
A964_RS01090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A964_RS01105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A964_RS01105	COG4499	WXG100 protein secretion system (Wss), protein YukC
A964_RS01165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A964_RS01170	COG1363	Peptidase, m42
A964_RS01185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A964_RS01190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A964_RS01205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A964_RS01225	COG1346	cytolysis
A964_RS01235	COG0601	transmembrane transport
A964_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A964_RS01245	COG1122	ATPase activity
A964_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS01255	COG1263	PTS System
A964_RS01260	COG0366	Alpha amylase catalytic
A964_RS01265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A964_RS01280	COG3959	Transketolase, thiamine diphosphate binding domain
A964_RS01285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A964_RS01290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A964_RS01310	COG1045	serine acetyltransferase
A964_RS01325	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A964_RS01345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A964_RS01355	COG4974	Belongs to the 'phage' integrase family
A964_RS01460	COG1396	sequence-specific DNA binding
A964_RS01465	COG2814	Major facilitator Superfamily
A964_RS01475	COG1732	Glycine betaine
A964_RS01610	COG0519	Catalyzes the synthesis of GMP from XMP
A964_RS01655	COG1695	Transcriptional regulator
A964_RS01670	COG1755	Isoprenylcysteine carboxyl methyltransferase
A964_RS01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A964_RS01715	COG0446	pyridine nucleotide-disulphide oxidoreductase
A964_RS01735	COG1131	(ABC) transporter
A964_RS01745	COG2190	(PTS) system
A964_RS01745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS01745	COG1263	PTS System
A964_RS01750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A964_RS01770	COG0768	penicillin binding
A964_RS01780	COG0513	Belongs to the DEAD box helicase family
A964_RS01795	COG1126	abc transporter atp-binding protein
A964_RS01805	COG0492	ferredoxin-NADP+ reductase activity
A964_RS01810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A964_RS01820	COG3579	cysteine-type endopeptidase activity
A964_RS01825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A964_RS01845	COG0116	Belongs to the methyltransferase superfamily
A964_RS01855	COG1854	S-ribosylhomocysteine lyase activity
A964_RS01860	COG4372	Transposase
A964_RS01860	COG1418	mRNA catabolic process
A964_RS01865	COG1131	(ABC) transporter
A964_RS01875	COG4585	Histidine kinase
A964_RS01880	COG2197	response regulator
A964_RS01890	COG0194	GDP metabolic process
A964_RS01900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A964_RS01905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A964_RS01910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A964_RS01910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A964_RS01920	COG2815	serine threonine protein kinase
A964_RS01920	COG0515	serine threonine protein kinase
A964_RS01930	COG4585	Histidine kinase
A964_RS01935	COG2197	response regulator
A964_RS01945	COG1098	S1 RNA binding domain
A964_RS01950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A964_RS01955	COG1349	DNA-binding transcription factor activity
A964_RS01965	COG1447	Phosphotransferase system cellobiose-specific component IIA
A964_RS01975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A964_RS01980	COG1882	Formate acetyltransferase
A964_RS02000	COG1739	Uncharacterized protein family UPF0029
A964_RS02005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A964_RS02010	COG1040	competence protein
A964_RS02045	COG0527	aspartate kinase activity
A964_RS02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A964_RS02055	COG1024	Enoyl-CoA hydratase
A964_RS02065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A964_RS02075	COG2070	2-Nitropropane dioxygenase
A964_RS02080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A964_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
A964_RS02090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A964_RS02105	COG0439	Biotin carboxylase
A964_RS02125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A964_RS02140	COG3716	PTS system mannose fructose sorbose family IID component
A964_RS02145	COG3715	PTS system
A964_RS02155	COG0561	phosphatase activity
A964_RS02170	COG2252	PERMEase
A964_RS02175	COG0802	atpase or kinase
A964_RS02185	COG1316	TRANSCRIPTIONal
A964_RS02195	COG0537	adenosine 5'-monophosphoramidase activity
A964_RS02210	COG1131	(ABC) transporter
A964_RS02215	COG4473	ABC transporter
A964_RS02225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A964_RS02240	COG0195	Participates in both transcription termination and antitermination
A964_RS02245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A964_RS02255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A964_RS02260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A964_RS02285	COG2860	membrane
A964_RS02295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A964_RS02295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A964_RS02300	COG1832	CoA-binding protein
A964_RS02320	COG5002	protein histidine kinase activity
A964_RS02340	COG1268	BioY protein
A964_RS02345	COG1234	tRNA 3'-trailer cleavage
A964_RS02360	COG0166	Belongs to the GPI family
A964_RS02365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A964_RS02370	COG0457	Tetratricopeptide repeat
A964_RS02370	COG0705	Rhomboid family
A964_RS02375	COG1744	ABC transporter substrate-binding protein PnrA-like
A964_RS02380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A964_RS02395	COG0706	membrane insertase activity
A964_RS02455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A964_RS02465	COG2153	protein acetylation
A964_RS02475	COG1442	glycosyl transferase family 8
A964_RS02475	COG1216	Glycosyl transferase, family 2
A964_RS02510	COG2801	Transposase and inactivated derivatives
A964_RS02520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A964_RS02530	COG0789	Transcriptional regulator
A964_RS02540	COG0656	L-ascorbic acid biosynthetic process
A964_RS02585	COG2226	methyltransferase
A964_RS02595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A964_RS02600	COG3414	Phosphotransferase system galactitol-specific IIB component
A964_RS02605	COG3775	system Galactitol-specific IIC component
A964_RS02610	COG0235	Class ii aldolase
A964_RS02620	COG3775	system Galactitol-specific IIC component
A964_RS02625	COG3414	Phosphotransferase system galactitol-specific IIB component
A964_RS02630	COG2207	Transcriptional regulator
A964_RS02640	COG1175	transmembrane transport
A964_RS02645	COG0395	ABC-type sugar transport system, permease component
A964_RS02665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A964_RS02670	COG2017	converts alpha-aldose to the beta-anomer
A964_RS02705	COG0673	inositol 2-dehydrogenase activity
A964_RS02715	COG2315	Protein conserved in bacteria
A964_RS02730	COG0742	ribosomal rna small subunit methyltransferase
A964_RS02745	COG3480	Lon protease (S16) C-terminal proteolytic domain
A964_RS02750	COG0737	Belongs to the 5'-nucleotidase family
A964_RS02755	COG4470	Protein conserved in bacteria
A964_RS02770	COG1132	(ABC) transporter
A964_RS02775	COG1132	(ABC) transporter
A964_RS02780	COG0512	Glutamine amidotransferase of anthranilate synthase
A964_RS02790	COG1268	BioY protein
A964_RS02805	COG0183	Belongs to the thiolase family
A964_RS02815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A964_RS02830	COG1940	carbohydrate kinase activity
A964_RS02835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A964_RS02840	COG1217	gtp-binding protein TYPA
A964_RS02865	COG3344	reverse transcriptase
A964_RS02880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A964_RS02890	COG0762	integral membrane protein
A964_RS02895	COG2302	S4 RNA-binding domain
A964_RS02900	COG3599	regulation of cell shape
A964_RS02915	COG0494	nUDIX hydrolase
A964_RS02920	COG0542	response to heat
A964_RS02925	COG4703	Protein of unknown function (DUF1797)
A964_RS02935	COG0765	amino acid transport
A964_RS02940	COG1126	abc transporter atp-binding protein
A964_RS02945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A964_RS02955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A964_RS02965	COG1722	exodeoxyribonuclease VII activity
A964_RS02975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A964_RS02980	COG1438	arginine binding
A964_RS02985	COG0497	DNA recombination
A964_RS02990	COG1307	EDD domain protein, DegV family
A964_RS02995	COG2755	lipolytic protein G-D-S-L family
A964_RS03040	COG1078	dGTPase activity
A964_RS03065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A964_RS03075	COG2884	Cell division ATP-binding protein ftsE
A964_RS03080	COG2177	Part of the ABC transporter FtsEX involved in
A964_RS03115	COG1199	ATP-dependent helicase activity
A964_RS03115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A964_RS03120	COG0436	Aminotransferase
A964_RS03125	COG0017	Asparaginyl-tRNA synthetase
A964_RS03145	COG1660	Displays ATPase and GTPase activities
A964_RS03175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A964_RS03185	COG0716	FMN binding
A964_RS03190	COG1605	Chorismate mutase
A964_RS03190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A964_RS03195	COG0038	chloride channel
A964_RS03200	COG0335	large ribosomal subunit rRNA binding
A964_RS03235	COG1136	(ABC) transporter
A964_RS03250	COG5002	protein histidine kinase activity
A964_RS03265	COG0772	Belongs to the SEDS family
A964_RS03285	COG0560	Phosphoserine phosphatase
A964_RS03300	COG0148	phosphopyruvate hydratase activity
A964_RS03320	COG1316	TRANSCRIPTIONal
A964_RS03355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A964_RS03355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A964_RS03395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A964_RS03415	COG0270	DNA (cytosine-5-)-methyltransferase activity
A964_RS03455	COG4695	Portal protein
A964_RS03460	COG0740	serine-type endopeptidase activity
A964_RS03525	COG1705	Flagellar rod assembly protein muramidase FlgJ
A964_RS03530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A964_RS03570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A964_RS03575	COG4555	ABC transporter
A964_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
A964_RS03605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A964_RS03610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A964_RS03630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A964_RS03635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A964_RS03655	COG3064	Membrane
A964_RS03655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A964_RS03670	COG3590	peptidase
A964_RS03675	COG3590	peptidase
A964_RS03715	COG1136	(ABC) transporter
A964_RS03730	COG0586	Pfam SNARE associated Golgi protein
A964_RS03735	COG4619	ABC transporter
A964_RS03740	COG0390	transport system, permease component
A964_RS03750	COG0583	DNA-binding transcription factor activity
A964_RS03760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A964_RS03765	COG2211	Major facilitator Superfamily
A964_RS03775	COG3250	beta-galactosidase activity
A964_RS03780	COG2186	Transcriptional regulator
A964_RS03785	COG0800	Aldolase
A964_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
A964_RS03825	COG1609	Transcriptional regulator
A964_RS03840	COG0438	transferase activity, transferring glycosyl groups
A964_RS03865	COG0765	amino acid transport
A964_RS03870	COG0765	amino acid transport
A964_RS03875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A964_RS03880	COG1126	abc transporter atp-binding protein
A964_RS03885	COG0745	RESPONSE REGULATOR receiver
A964_RS03890	COG5002	protein histidine kinase activity
A964_RS03895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A964_RS03900	COG2832	Protein of unknown function (DUF454)
A964_RS03910	COG1196	nuclear chromosome segregation
A964_RS03915	COG0561	phosphatase activity
A964_RS03920	COG0561	phosphatase activity
A964_RS03925	COG0552	protein localization to endoplasmic reticulum
A964_RS03935	COG3344	reverse transcriptase
A964_RS03940	COG3689	TIGRFAM TIGR03943 family protein
A964_RS03945	COG0701	Predicted permease
A964_RS03960	COG2183	response to ionizing radiation
A964_RS03965	COG3091	SprT-like family
A964_RS03970	COG1983	PspC domain protein
A964_RS04010	COG0826	peptidase U32
A964_RS04015	COG4443	Transcriptional Coactivator p15 (PC4)
A964_RS04025	COG1914	H( )-stimulated, divalent metal cation uptake system
A964_RS04040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A964_RS04040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A964_RS04065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A964_RS04090	COG1164	Oligoendopeptidase f
A964_RS04100	COG0772	Belongs to the SEDS family
A964_RS04120	COG0768	penicillin binding
A964_RS04135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A964_RS04140	COG2223	nitrite transmembrane transporter activity
A964_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A964_RS04170	COG2011	ABC-type metal ion transport system permease component
A964_RS04175	COG1464	Belongs to the NlpA lipoprotein family
A964_RS04180	COG0513	Belongs to the DEAD box helicase family
A964_RS04190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A964_RS04195	COG0204	Acyl-transferase
A964_RS04205	COG0658	competence protein
A964_RS04205	COG2333	competence protein COMEC
A964_RS04210	COG0561	phosphatase activity
A964_RS04215	COG1609	Transcriptional regulator
A964_RS04220	COG0657	acetylesterase activity
A964_RS04225	COG2226	methyltransferase
A964_RS04235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A964_RS04240	COG3711	transcriptional antiterminator
A964_RS04245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS04245	COG1263	PTS System
A964_RS04250	COG1263	PTS System
A964_RS04250	COG2190	(PTS) system
A964_RS04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS04260	COG3835	regulator
A964_RS04265	COG1929	Belongs to the glycerate kinase type-1 family
A964_RS04270	COG2610	gluconate transmembrane transporter activity
A964_RS04280	COG1846	Transcriptional regulator
A964_RS04295	COG0363	glucosamine-6-phosphate deaminase activity
A964_RS04300	COG0435	Glutathione S-transferase
A964_RS04305	COG1187	pseudouridine synthase activity
A964_RS04325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A964_RS04330	COG4122	O-methyltransferase activity
A964_RS04340	COG4894	glucomannan catabolic process
A964_RS04350	COG1811	Na channel or pump
A964_RS04355	COG1442	glycosyl transferase family 8
A964_RS04365	COG1476	TRANSCRIPTIONal
A964_RS04380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A964_RS04385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A964_RS04390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A964_RS04405	COG1012	belongs to the aldehyde dehydrogenase family
A964_RS04410	COG0726	polysaccharide deacetylase
A964_RS04425	COG1956	GAF domain-containing protein
A964_RS04430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A964_RS04440	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A964_RS04440	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A964_RS04465	COG4721	ABC-type cobalt transport system, permease component
A964_RS04470	COG1122	ATPase activity
A964_RS04480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A964_RS04510	COG4109	DRTGG domain
A964_RS04515	COG0024	Methionine aminopeptidase
A964_RS04525	COG2246	polysaccharide biosynthetic process
A964_RS04530	COG4708	membrane
A964_RS04540	COG1597	lipid kinase activity
A964_RS04545	COG1523	belongs to the glycosyl hydrolase 13 family
A964_RS04560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A964_RS04645	COG2321	neutral zinc metallopeptidase
A964_RS04670	COG0488	(ABC) transporter
A964_RS04675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A964_RS04680	COG0022	dehydrogenase e1 component
A964_RS04680	COG0508	dehydrogenase complex catalyzes the overall conversion of
A964_RS04685	COG0508	dehydrogenase complex catalyzes the overall conversion of
A964_RS04695	COG0095	Lipoate-protein ligase
A964_RS04705	COG3442	glutamine amidotransferase
A964_RS04710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A964_RS04715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A964_RS04740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A964_RS04750	COG0647	UMP catabolic process
A964_RS04760	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
A964_RS04765	COG1518	maintenance of DNA repeat elements
A964_RS04770	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A964_RS04790	COG0481	GTPase activity
A964_RS04800	COG1418	mRNA catabolic process
A964_RS04805	COG0456	acetyltransferase
A964_RS04815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A964_RS04840	COG1131	(ABC) transporter
A964_RS04845	COG1725	Transcriptional regulator
A964_RS04855	COG0205	6-phosphofructokinase activity
A964_RS04860	COG0469	pyruvate kinase activity
A964_RS04870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A964_RS04875	COG2824	Alkylphosphonate utilization operon protein PhnA
A964_RS04880	COG0765	amino acid transport
A964_RS04885	COG1126	abc transporter atp-binding protein
A964_RS04900	COG1072	(Pantothenic acid kinase))
A964_RS04905	COG2813	Specifically methylates the guanine in position
A964_RS04915	COG1744	ABC transporter substrate-binding protein PnrA-like
A964_RS04920	COG3845	ABC transporter
A964_RS04925	COG4603	Belongs to the binding-protein-dependent transport system permease family
A964_RS04930	COG1079	Belongs to the binding-protein-dependent transport system permease family
A964_RS04950	COG3764	Sortase (surface protein transpeptidase)
A964_RS04955	COG0346	lactoylglutathione lyase activity
A964_RS04985	COG2188	Transcriptional regulator
A964_RS05000	COG1464	Belongs to the NlpA lipoprotein family
A964_RS05015	COG1136	(ABC) transporter
A964_RS05025	COG0745	RESPONSE REGULATOR receiver
A964_RS05030	COG5002	protein histidine kinase activity
A964_RS05035	COG4974	Belongs to the 'phage' integrase family
A964_RS05040	COG4166	transmembrane transport
A964_RS05055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A964_RS05060	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A964_RS05065	COG5002	protein histidine kinase activity
A964_RS05070	COG0745	RESPONSE REGULATOR receiver
A964_RS05080	COG0704	Plays a role in the regulation of phosphate uptake
A964_RS05085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A964_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A964_RS05095	COG0581	inorganic phosphate transmembrane transporter activity
A964_RS05100	COG0573	inorganic phosphate transmembrane transporter activity
A964_RS05110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A964_RS05110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A964_RS05115	COG0483	inositol monophosphate 1-phosphatase activity
A964_RS05130	COG0196	riboflavin kinase activity
A964_RS05135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A964_RS05165	COG1136	(ABC) transporter
A964_RS05170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A964_RS05175	COG0758	DNA mediated transformation
A964_RS05180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A964_RS05185	COG4604	ABC transporter, ATP-binding protein
A964_RS05190	COG4605	iron ion homeostasis
A964_RS05195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A964_RS05200	COG0110	maltose O-acetyltransferase activity
A964_RS05210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A964_RS05215	COG1376	ErfK ybiS ycfS ynhG family protein
A964_RS05220	COG1966	Carbon starvation protein
A964_RS05225	COG3279	Response regulator of the LytR AlgR family
A964_RS05230	COG3275	phosphorelay sensor kinase activity
A964_RS05335	COG0505	Belongs to the CarA family
A964_RS05345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A964_RS05365	COG0488	(ABC) transporter
A964_RS05375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A964_RS05385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A964_RS05425	COG0095	Lipoate-protein ligase
A964_RS05435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A964_RS05440	COG4684	Psort location CytoplasmicMembrane, score
A964_RS05445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A964_RS05455	COG1132	(ABC) transporter
A964_RS05485	COG2890	protein-(glutamine-N5) methyltransferase activity
A964_RS05500	COG1942	4-Oxalocrotonate Tautomerase
A964_RS05515	COG1053	succinate dehydrogenase
A964_RS05515	COG3976	FMN-binding domain protein
A964_RS05515	COG0431	NADPH-dependent FMN reductase
A964_RS05525	COG2233	PERMEase
A964_RS05540	COG0477	Major facilitator Superfamily
A964_RS05555	COG4221	oxidoreductase activity
A964_RS05560	COG0280	phosphate acetyltransferase
A964_RS05565	COG0564	pseudouridine synthase activity
A964_RS05570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A964_RS05575	COG2357	RelA SpoT domain protein
A964_RS05590	COG1104	cysteine desulfurase activity
A964_RS05610	COG0628	permease
A964_RS05615	COG2723	6-phospho-beta-galactosidase activity
A964_RS05625	COG0561	phosphatase activity
A964_RS05635	COG0038	chloride channel
A964_RS05645	COG1177	transmembrane transport
A964_RS05650	COG1176	ABC-type spermidine putrescine transport system, permease component I
A964_RS05660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A964_RS05665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A964_RS05685	COG0285	dihydrofolate synthase activity
A964_RS05690	COG2962	Rard protein
A964_RS05705	COG0726	polysaccharide deacetylase
A964_RS05710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A964_RS05725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A964_RS05730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A964_RS05735	COG1012	belongs to the aldehyde dehydrogenase family
A964_RS05820	COG2261	transglycosylase associated protein
A964_RS05845	COG1115	amino acid carrier protein
A964_RS05850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A964_RS05860	COG1346	cytolysis
A964_RS05875	COG0539	negative regulation of cytoplasmic translation
A964_RS05895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A964_RS05905	COG0187	DNA topoisomerase II activity
A964_RS05910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A964_RS05915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A964_RS05925	COG1083	cytidylyl-transferase
A964_RS05925	COG2755	lipolytic protein G-D-S-L family
A964_RS05940	COG2089	acid synthase
A964_RS05955	COG1216	Glycosyl transferase, family 2
A964_RS05955	COG1442	glycosyl transferase family 8
A964_RS05960	COG1442	glycosyl transferase family 8
A964_RS05960	COG1216	Glycosyl transferase, family 2
A964_RS05975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A964_RS06000	COG1316	TRANSCRIPTIONal
A964_RS06025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A964_RS06060	COG3842	ATPase activity
A964_RS06075	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A964_RS06080	COG3527	Alpha-acetolactate decarboxylase
A964_RS06085	COG0028	Belongs to the TPP enzyme family
A964_RS06090	COG0457	Tetratricopeptide repeat
A964_RS06095	COG0628	permease
A964_RS06105	COG1051	belongs to the nudix hydrolase family
A964_RS06110	COG5492	domain, Protein
A964_RS06115	COG1088	dTDP-glucose 4,6-dehydratase activity
A964_RS06125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A964_RS06130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A964_RS06140	COG2384	SAM-dependent methyltransferase
A964_RS06160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A964_RS06160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A964_RS06165	COG0300	oxidoreductase activity
A964_RS06180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A964_RS06200	COG1523	belongs to the glycosyl hydrolase 13 family
A964_RS06210	COG1573	uracil-dna glycosylase
A964_RS06215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A964_RS06225	COG0584	glycerophosphoryl diester phosphodiesterase
A964_RS06240	COG0534	Mate efflux family protein
A964_RS06270	COG2176	DNA-directed DNA polymerase activity
A964_RS06280	COG4974	Belongs to the 'phage' integrase family
A964_RS06310	COG1674	ftsk spoiiie
A964_RS06350	COG2040	homocysteine
A964_RS06355	COG0833	amino acid
A964_RS06390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A964_RS06400	COG3425	synthase
A964_RS06415	COG1272	protein, Hemolysin III
A964_RS06460	COG0745	RESPONSE REGULATOR receiver
A964_RS06465	COG2357	RelA SpoT domain protein
A964_RS06470	COG1132	(ABC) transporter
A964_RS06485	COG0737	Belongs to the 5'-nucleotidase family
A964_RS06490	COG0242	peptide deformylase activity
A964_RS06495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A964_RS06505	COG1132	(ABC) transporter
A964_RS06520	COG0488	(ABC) transporter
A964_RS06550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A964_RS06550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A964_RS06550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A964_RS06555	COG1105	Belongs to the carbohydrate kinase PfkB family
A964_RS06560	COG1349	DNA-binding transcription factor activity
A964_RS06565	COG1705	Flagellar rod assembly protein muramidase FlgJ
A964_RS06565	COG1388	LysM domain
A964_RS06615	COG1837	Belongs to the UPF0109 family
A964_RS06620	COG0228	four-way junction DNA binding
A964_RS06625	COG0577	efflux transmembrane transporter activity
A964_RS06630	COG1136	(ABC) transporter
A964_RS06635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A964_RS06645	COG0505	Belongs to the CarA family
A964_RS06655	COG0564	pseudouridine synthase activity
A964_RS06665	COG0583	DNA-binding transcription factor activity
A964_RS06670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A964_RS06695	COG1104	cysteine desulfurase activity
A964_RS06705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A964_RS06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A964_RS06735	COG1368	sulfuric ester hydrolase activity
A964_RS06740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A964_RS06750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A964_RS06780	COG2244	polysaccharide biosynthetic process
A964_RS06790	COG1120	ATPase activity
A964_RS06795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A964_RS06800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A964_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A964_RS06820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A964_RS06825	COG1253	flavin adenine dinucleotide binding
A964_RS06830	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A964_RS06835	COG1242	4 iron, 4 sulfur cluster binding
A964_RS06840	COG0671	phosphoesterase, PA-phosphatase related
A964_RS06845	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A964_RS06875	COG0681	Belongs to the peptidase S26 family
A964_RS06885	COG0297	glycogen (starch) synthase activity
A964_RS06925	COG3475	LICD family
A964_RS06940	COG0463	Glycosyl transferase, family 2
A964_RS06945	COG1215	transferase activity, transferring glycosyl groups
A964_RS06955	COG1091	dTDP-4-dehydrorhamnose reductase activity
A964_RS06960	COG2151	metal-sulfur cluster biosynthetic enzyme
A964_RS06965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A964_RS06970	COG0358	DNA primase activity
A964_RS06975	COG1970	mechanosensitive ion channel activity
A964_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A964_RS06995	COG0004	ammonium transporteR
A964_RS07005	COG1054	Belongs to the UPF0176 family
A964_RS07015	COG2271	Major facilitator Superfamily
A964_RS07020	COG0058	SHG alpha-glucan phosphorylase activity
A964_RS07025	COG1640	4-alpha-glucanotransferase
A964_RS07030	COG1609	Transcriptional regulator
A964_RS07040	COG1175	transmembrane transport
A964_RS07045	COG3833	ABC-type maltose transport systems, permease component
A964_RS07050	COG3104	oligopeptide transport
A964_RS07070	COG0438	transferase activity, transferring glycosyl groups
A964_RS07100	COG1442	glycosyl transferase family 8
A964_RS07105	COG1442	glycosyl transferase family 8
A964_RS07105	COG1216	Glycosyl transferase, family 2
A964_RS07110	COG1442	glycosyl transferase family 8
A964_RS07115	COG1442	glycosyl transferase family 8
A964_RS07115	COG1216	Glycosyl transferase, family 2
A964_RS07120	COG1442	glycosyl transferase family 8
A964_RS07150	COG0765	amino acid transport
A964_RS07155	COG1126	abc transporter atp-binding protein
A964_RS07180	COG2309	aminopeptidase activity
A964_RS07190	COG0154	amidase activity
A964_RS07195	COG1187	pseudouridine synthase activity
A964_RS07200	COG0656	L-ascorbic acid biosynthetic process
A964_RS07205	COG0778	Nitroreductase
A964_RS07210	COG0346	lactoylglutathione lyase activity
A964_RS07215	COG0463	Glycosyl transferase, family 2
A964_RS07220	COG1113	amino acid transport
A964_RS07225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A964_RS07230	COG0557	exoribonuclease II activity
A964_RS07240	COG2814	Major facilitator Superfamily
A964_RS07250	COG1131	(ABC) transporter
A964_RS07260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A964_RS07265	COG1396	sequence-specific DNA binding
A964_RS07305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A964_RS07310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A964_RS07330	COG1702	phosphate starvation-inducible protein PhoH
A964_RS07355	COG0233	cytoplasmic translational termination
A964_RS07370	COG0444	Belongs to the ABC transporter superfamily
A964_RS07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A964_RS07380	COG0601	transmembrane transport
A964_RS07385	COG0747	negative chemotaxis
A964_RS07390	COG0081	regulation of translation
A964_RS07400	COG2826	transposase and inactivated derivatives, IS30 family
A964_RS07410	COG1473	amidohydrolase
A964_RS07415	COG0583	DNA-binding transcription factor activity
A964_RS07430	COG2801	Transposase and inactivated derivatives
A964_RS07435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A964_RS07440	COG1674	ftsk spoiiie
A964_RS07445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A964_RS07470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A964_RS07500	COG0673	inositol 2-dehydrogenase activity
A964_RS07515	COG1028	Short-chain dehydrogenase reductase Sdr
A964_RS07575	COG1114	Component of the transport system for branched-chain amino acids
A964_RS07580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A964_RS07580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A964_RS07595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A964_RS07605	COG0708	Exodeoxyribonuclease III
A964_RS07610	COG1393	Belongs to the ArsC family
A964_RS07615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A964_RS07620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A964_RS07650	COG0470	DNA polymerase III
A964_RS07665	COG0517	IMP dehydrogenase activity
A964_RS07685	COG0559	Belongs to the binding-protein-dependent transport system permease family
A964_RS07705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A964_RS07710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A964_RS07720	COG0531	amino acid
A964_RS07725	COG0569	domain protein
A964_RS07730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A964_RS07740	COG1187	pseudouridine synthase activity
A964_RS07790	COG1827	regulation of RNA biosynthetic process
A964_RS07805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A964_RS07810	COG1254	Belongs to the acylphosphatase family
A964_RS07820	COG0765	amino acid transport
A964_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A964_RS07840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A964_RS07875	COG1484	DNA-dependent DNA replication
A964_RS07890	COG5002	protein histidine kinase activity
A964_RS07895	COG0745	RESPONSE REGULATOR receiver
A964_RS07910	COG1704	LemA family
A964_RS07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A964_RS07925	COG0569	domain protein
A964_RS07950	COG1114	Component of the transport system for branched-chain amino acids
A964_RS07955	COG1063	alcohol dehydrogenase
A964_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A964_RS07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A964_RS07990	COG0217	transcriptional regulatory protein
A964_RS07995	COG2376	Dihydroxyacetone kinase
A964_RS08000	COG1309	transcriptional regulator
A964_RS08005	COG2376	Dihydroxyacetone kinase
A964_RS08010	COG1461	Dihydroxyacetone kinase
A964_RS08015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A964_RS08020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A964_RS08030	COG0789	Transcriptional regulator
A964_RS08045	COG2226	methyltransferase
A964_RS08050	COG0799	negative regulation of ribosome biogenesis
A964_RS08060	COG1713	HD superfamily hydrolase involved in NAD metabolism
A964_RS08065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A964_RS08070	COG1534	Rna-binding protein
A964_RS08075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A964_RS08080	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A964_RS08105	COG0574	Belongs to the PEP-utilizing enzyme family
A964_RS08105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A964_RS08115	COG0517	IMP dehydrogenase activity
A964_RS08125	COG1335	isochorismatase
A964_RS08130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A964_RS08135	COG0436	Aminotransferase
A964_RS08140	COG0589	response to stress
A964_RS08145	COG0561	phosphatase activity
A964_RS08150	COG0252	asparaginase activity
A964_RS08160	COG4989	oxidoreductase activity
A964_RS08165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A964_RS08170	COG3942	CHAP domain
A964_RS08170	COG1705	Flagellar rod assembly protein muramidase FlgJ
A964_RS08180	COG0736	holo-[acyl-carrier-protein] synthase activity
A964_RS08185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A964_RS08195	COG1482	cell wall glycoprotein biosynthetic process
A964_RS08200	COG1940	carbohydrate kinase activity
A964_RS08205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS08205	COG1263	PTS System
A964_RS08205	COG2190	(PTS) system
A964_RS08210	COG1621	beta-fructofuranosidase activity
A964_RS08215	COG1609	Transcriptional regulator
A964_RS08220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A964_RS08230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A964_RS08250	COG2131	deaminase
A964_RS08265	COG2814	Major facilitator Superfamily
A964_RS08290	COG0629	single-stranded DNA binding
A964_RS08295	COG0360	Binds together with S18 to 16S ribosomal RNA
A964_RS08300	COG1194	a g-specific adenine glycosylase
A964_RS08310	COG3118	belongs to the thioredoxin family
A964_RS08340	COG0681	Belongs to the peptidase S26 family
A964_RS08345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A964_RS08365	COG1882	Formate acetyltransferase
A964_RS08370	COG3576	pyridoxamine 5-phosphate
A964_RS08375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A964_RS08390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A964_RS08400	COG2814	Major facilitator Superfamily
A964_RS08405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A964_RS08420	COG0142	geranyltranstransferase activity
A964_RS08425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A964_RS08430	COG4988	ABC transporter
A964_RS08435	COG1294	oxidase, subunit
A964_RS08440	COG1271	oxidase subunit
A964_RS08445	COG1252	NADH dehydrogenase
A964_RS08480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A964_RS08485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A964_RS08485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A964_RS08485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A964_RS08490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A964_RS08495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A964_RS08500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A964_RS08500	COG3711	transcriptional antiterminator
A964_RS08520	COG4221	oxidoreductase activity
A964_RS08530	COG0656	L-ascorbic acid biosynthetic process
A964_RS08535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A964_RS08550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A964_RS08555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A964_RS08560	COG0789	Transcriptional regulator
A964_RS08575	COG2081	HI0933 family
A964_RS08600	COG0456	acetyltransferase
A964_RS08605	COG1214	PFAM Peptidase M22, glycoprotease
A964_RS08620	COG3942	CHAP domain
A964_RS08625	COG0174	glutamine synthetase
A964_RS08630	COG0789	Transcriptional regulator
A964_RS08645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A964_RS08670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A964_RS08695	COG1162	GTPase activity
A964_RS08720	COG0084	hydrolase, TatD family'
A964_RS08745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A964_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A964_RS08755	COG1696	Membrane protein involved in D-alanine export
A964_RS08775	COG0745	RESPONSE REGULATOR receiver
A964_RS08785	COG3314	Sporulation integral membrane protein YlbJ
A964_RS08795	COG3448	diguanylate cyclase activity
A964_RS08795	COG4175	Glycine betaine
A964_RS08800	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A964_RS08820	COG1070	Carbohydrate kinase
A964_RS08830	COG3775	system Galactitol-specific IIC component
A964_RS08835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A964_RS08845	COG1609	Transcriptional regulator
A964_RS08930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A964_RS08935	COG1428	Deoxynucleoside kinase
A964_RS08945	COG0542	response to heat
A964_RS08950	COG4463	regulation of RNA biosynthetic process
A964_RS08960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A964_RS08970	COG0450	alkyl hydroperoxide reductase
A964_RS08985	COG0025	NhaP-type Na H and K H
A964_RS08995	COG1619	proteins homologs of microcin C7 resistance protein MccF
A964_RS09000	COG3590	peptidase
A964_RS09025	COG1609	Transcriptional regulator
A964_RS09050	COG2176	DNA-directed DNA polymerase activity
A964_RS09055	COG1705	Flagellar rod assembly protein muramidase FlgJ
A964_RS09055	COG1388	LysM domain
A964_RS09070	COG4589	Belongs to the CDS family
A964_RS09075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A964_RS09080	COG1862	Preprotein translocase
A964_RS09100	COG3493	citrate carrier protein
A964_RS09105	COG3290	protein histidine kinase activity
A964_RS09110	COG4565	transcriptional regulatory protein
A964_RS09115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A964_RS09125	COG3842	ATPase activity
A964_RS09210	COG0737	Belongs to the 5'-nucleotidase family
A964_RS09220	COG1363	Peptidase, m42
A964_RS09240	COG4753	response regulator
A964_RS09240	COG2207	Transcriptional regulator
A964_RS09245	COG2972	Histidine kinase
A964_RS09250	COG3716	PTS system mannose fructose sorbose family IID component
A964_RS09255	COG3715	PTS system
A964_RS09285	COG1131	(ABC) transporter
A964_RS09295	COG2274	protein secretion by the type I secretion system
A964_RS09300	COG3290	protein histidine kinase activity
A964_RS09315	COG2190	(PTS) system
A964_RS09315	COG1263	PTS System
A964_RS09315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A964_RS09320	COG5002	protein histidine kinase activity
A964_RS09325	COG0745	RESPONSE REGULATOR receiver
A964_RS09340	COG0581	inorganic phosphate transmembrane transporter activity
A964_RS09345	COG0573	inorganic phosphate transmembrane transporter activity
A964_RS09360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A964_RS09375	COG0789	Transcriptional regulator
A964_RS09385	COG0494	nUDIX hydrolase
A964_RS09400	COG0456	acetyltransferase
A964_RS09405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A964_RS09430	COG0582	viral genome integration into host DNA
A964_RS09440	COG2946	Replication initiation factor
A964_RS09460	COG2378	regulation of single-species biofilm formation
A964_RS09465	COG0693	protein deglycase activity
A964_RS09550	COG1131	(ABC) transporter
A964_RS09595	COG1131	(ABC) transporter
A964_RS09605	COG1396	sequence-specific DNA binding
A964_RS09615	COG1694	Mazg nucleotide pyrophosphohydrolase
A964_RS09620	COG1611	Belongs to the LOG family
A964_RS09630	COG2897	thiosulfate sulfurtransferase activity
A964_RS09645	COG0371	Dehydrogenase
A964_RS09655	COG0646	methionine synthase
A964_RS09655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A964_RS09670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A964_RS09685	COG0745	RESPONSE REGULATOR receiver
A964_RS09690	COG2770	Histidine kinase
A964_RS09690	COG2205	protein histidine kinase activity
A964_RS09705	COG2814	Major facilitator Superfamily
A964_RS09710	COG4667	esterase of the alpha-beta hydrolase superfamily
A964_RS09730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A964_RS09735	COG0564	pseudouridine synthase activity
A964_RS09755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A964_RS09760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A964_RS09780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A964_RS09785	COG1116	anion transmembrane transporter activity
A964_RS09785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A964_RS09790	COG4120	Belongs to the binding-protein-dependent transport system permease family
A964_RS09800	COG0561	phosphatase activity
A964_RS09805	COG2514	catechol 2,3-dioxygenase activity
A964_RS09815	COG0602	queuosine metabolic process
A964_RS09835	COG1328	CTP reductase activity
A964_RS09855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A964_RS09865	COG1393	Belongs to the ArsC family
A964_RS09870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A964_RS09880	COG2818	Glycosylase
A964_RS09925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A964_RS09930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A964_RS09950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A964_RS09955	COG3344	reverse transcriptase
A964_RS10010	COG0582	viral genome integration into host DNA
A964_RS10020	COG0745	RESPONSE REGULATOR receiver
A964_RS10025	COG5002	protein histidine kinase activity
A964_RS10030	COG1288	antiporter activity
A964_RS10040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A964_RS10045	COG3852	Histidine kinase
A964_RS10050	COG0784	Response regulator, receiver
A964_RS10055	COG0517	IMP dehydrogenase activity
A964_RS10055	COG1125	glycine betaine transport
A964_RS10060	COG1174	glycine betaine transport
A964_RS10065	COG0392	lysyltransferase activity
A964_RS10065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A964_RS10075	COG3759	membrane
A964_RS10105	COG0305	Participates in initiation and elongation during chromosome replication
A964_RS10125	COG2095	MarC family integral membrane protein
A964_RS10135	COG1760	l-serine dehydratase
A964_RS10140	COG1760	l-serine dehydratase
A964_RS10145	COG0741	lytic transglycosylase activity
A964_RS10170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A964_RS10175	COG0612	Peptidase, M16
A964_RS10180	COG0612	Peptidase, M16
A964_RS10185	COG2501	S4 domain
A964_RS10205	COG0516	GMP reductase activity
A964_RS10205	COG0517	IMP dehydrogenase activity
A964_RS10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A964_RS10230	COG0454	-acetyltransferase
A964_RS10245	COG0549	Belongs to the carbamate kinase family
A964_RS10260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A964_RS10265	COG0488	(ABC) transporter
A964_RS10270	COG4485	Bacterial membrane protein, YfhO
A964_RS10290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A964_RS10295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A964_RS10300	COG1475	DNA binding
A964_RS10310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB