locus-tag	class	description
SAH002_RS00010	COG0592	DNA-directed DNA polymerase activity
SAH002_RS00015	COG1597	lipid kinase activity
SAH002_RS00030	COG0012	GTP binding
SAH002_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SAH002_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAH002_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAH002_RS00260	COG0436	Aminotransferase
SAH002_RS00275	COG0416	fatty acid biosynthetic process
SAH002_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAH002_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAH002_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SAH002_RS00315	COG0138	bifunctional purine biosynthesis protein purh
SAH002_RS00330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SAH002_RS00340	COG1175	transmembrane transport
SAH002_RS00345	COG0395	ABC-type sugar transport system, permease component
SAH002_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAH002_RS00370	COG3458	cephalosporin-C deacetylase activity
SAH002_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAH002_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAH002_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAH002_RS00425	COG2755	lipolytic protein G-D-S-L family
SAH002_RS00425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAH002_RS00430	COG1454	alcohol dehydrogenase
SAH002_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
SAH002_RS00435	COG1064	alcohol dehydrogenase
SAH002_RS00445	COG0534	Mate efflux family protein
SAH002_RS00555	COG0201	protein transport
SAH002_RS00560	COG0563	adenylate kinase activity
SAH002_RS00570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAH002_RS00580	COG0202	RNA polymerase activity
SAH002_RS00715	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAH002_RS00730	COG0443	Heat shock 70 kDa protein
SAH002_RS00740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAH002_RS00750	COG0351	phosphomethylpyrimidine kinase
SAH002_RS00755	COG4720	Psort location CytoplasmicMembrane, score
SAH002_RS00765	COG0668	transmembrane transport
SAH002_RS00795	COG0756	dUTP diphosphatase activity
SAH002_RS00810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAH002_RS00820	COG1879	ABC-type sugar transport system periplasmic component
SAH002_RS00825	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAH002_RS00840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAH002_RS00845	COG1609	Transcriptional regulator
SAH002_RS00850	COG0577	efflux transmembrane transporter activity
SAH002_RS00855	COG1136	(ABC) transporter
SAH002_RS00860	COG0745	RESPONSE REGULATOR receiver
SAH002_RS00865	COG5002	protein histidine kinase activity
SAH002_RS00880	COG0191	fructose-bisphosphate aldolase activity
SAH002_RS00900	COG1461	Dihydroxyacetone kinase
SAH002_RS00920	COG1126	abc transporter atp-binding protein
SAH002_RS00925	COG0765	amino acid transport
SAH002_RS00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAH002_RS00955	COG0719	Fe-S assembly protein
SAH002_RS00960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAH002_RS00970	COG0719	Fe-S assembly protein
SAH002_RS00975	COG1686	Belongs to the peptidase S11 family
SAH002_RS00980	COG1686	Belongs to the peptidase S11 family
SAH002_RS00985	COG4166	transmembrane transport
SAH002_RS00990	COG0601	transmembrane transport
SAH002_RS00995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAH002_RS01000	COG0444	Belongs to the ABC transporter superfamily
SAH002_RS01005	COG4608	Belongs to the ABC transporter superfamily
SAH002_RS01045	COG1121	(ABC) transporter
SAH002_RS01050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAH002_RS01065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAH002_RS01065	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAH002_RS01130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAH002_RS01135	COG1363	Peptidase, m42
SAH002_RS01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAH002_RS01155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAH002_RS01170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAH002_RS01190	COG1346	cytolysis
SAH002_RS01200	COG0601	transmembrane transport
SAH002_RS01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAH002_RS01210	COG1122	ATPase activity
SAH002_RS01220	COG1263	PTS System
SAH002_RS01220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS01225	COG0366	Alpha amylase catalytic
SAH002_RS01230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAH002_RS01245	COG3959	Transketolase, thiamine diphosphate binding domain
SAH002_RS01250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SAH002_RS01255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAH002_RS01275	COG1045	serine acetyltransferase
SAH002_RS01290	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAH002_RS01310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAH002_RS01320	COG4974	Belongs to the 'phage' integrase family
SAH002_RS01420	COG1396	sequence-specific DNA binding
SAH002_RS01425	COG2814	Major facilitator Superfamily
SAH002_RS01435	COG1732	Glycine betaine
SAH002_RS01530	COG0582	viral genome integration into host DNA
SAH002_RS01605	COG0519	Catalyzes the synthesis of GMP from XMP
SAH002_RS01660	COG1695	Transcriptional regulator
SAH002_RS01675	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAH002_RS01715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAH002_RS01720	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAH002_RS01740	COG1131	(ABC) transporter
SAH002_RS01750	COG1263	PTS System
SAH002_RS01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS01750	COG2190	(PTS) system
SAH002_RS01755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAH002_RS01775	COG0768	penicillin binding
SAH002_RS01785	COG0513	Belongs to the DEAD box helicase family
SAH002_RS01800	COG1126	abc transporter atp-binding protein
SAH002_RS01810	COG0492	ferredoxin-NADP+ reductase activity
SAH002_RS01815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAH002_RS01825	COG3579	cysteine-type endopeptidase activity
SAH002_RS01830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAH002_RS01850	COG0116	Belongs to the methyltransferase superfamily
SAH002_RS01860	COG1854	S-ribosylhomocysteine lyase activity
SAH002_RS01865	COG4372	Transposase
SAH002_RS01865	COG1418	mRNA catabolic process
SAH002_RS01870	COG1131	(ABC) transporter
SAH002_RS01880	COG4585	Histidine kinase
SAH002_RS01895	COG0194	GDP metabolic process
SAH002_RS01905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAH002_RS01910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAH002_RS01915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAH002_RS01915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAH002_RS01925	COG0515	serine threonine protein kinase
SAH002_RS01925	COG2815	serine threonine protein kinase
SAH002_RS01935	COG4585	Histidine kinase
SAH002_RS01940	COG2197	response regulator
SAH002_RS01950	COG1098	S1 RNA binding domain
SAH002_RS01955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAH002_RS01960	COG1349	DNA-binding transcription factor activity
SAH002_RS01970	COG1447	Phosphotransferase system cellobiose-specific component IIA
SAH002_RS01980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAH002_RS01985	COG1882	Formate acetyltransferase
SAH002_RS02005	COG1739	Uncharacterized protein family UPF0029
SAH002_RS02010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAH002_RS02015	COG1040	competence protein
SAH002_RS02050	COG0527	aspartate kinase activity
SAH002_RS02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAH002_RS02060	COG1024	Enoyl-CoA hydratase
SAH002_RS02070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAH002_RS02080	COG2070	2-Nitropropane dioxygenase
SAH002_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SAH002_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
SAH002_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAH002_RS02110	COG0439	Biotin carboxylase
SAH002_RS02130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAH002_RS02145	COG3716	PTS system mannose fructose sorbose family IID component
SAH002_RS02150	COG3715	PTS system
SAH002_RS02160	COG0561	phosphatase activity
SAH002_RS02175	COG2252	PERMEase
SAH002_RS02180	COG0802	atpase or kinase
SAH002_RS02190	COG1316	TRANSCRIPTIONal
SAH002_RS02200	COG0537	adenosine 5'-monophosphoramidase activity
SAH002_RS02215	COG1131	(ABC) transporter
SAH002_RS02220	COG4473	ABC transporter
SAH002_RS02230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAH002_RS02245	COG0195	Participates in both transcription termination and antitermination
SAH002_RS02250	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAH002_RS02265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAH002_RS02290	COG2860	membrane
SAH002_RS02300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAH002_RS02300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAH002_RS02305	COG1832	CoA-binding protein
SAH002_RS02325	COG5002	protein histidine kinase activity
SAH002_RS02345	COG1268	BioY protein
SAH002_RS02350	COG1234	tRNA 3'-trailer cleavage
SAH002_RS02365	COG0166	Belongs to the GPI family
SAH002_RS02370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAH002_RS02375	COG0457	Tetratricopeptide repeat
SAH002_RS02375	COG0705	Rhomboid family
SAH002_RS02380	COG1744	ABC transporter substrate-binding protein PnrA-like
SAH002_RS02385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAH002_RS02470	COG2153	protein acetylation
SAH002_RS02480	COG1216	Glycosyl transferase, family 2
SAH002_RS02480	COG1442	glycosyl transferase family 8
SAH002_RS02520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAH002_RS02530	COG0789	Transcriptional regulator
SAH002_RS02535	COG1063	alcohol dehydrogenase
SAH002_RS02540	COG0656	L-ascorbic acid biosynthetic process
SAH002_RS02625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAH002_RS02640	COG0673	inositol 2-dehydrogenase activity
SAH002_RS02650	COG3328	transposase activity
SAH002_RS02655	COG2315	Protein conserved in bacteria
SAH002_RS02670	COG0742	ribosomal rna small subunit methyltransferase
SAH002_RS02685	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAH002_RS02695	COG4470	Protein conserved in bacteria
SAH002_RS02710	COG1132	(ABC) transporter
SAH002_RS02715	COG1132	(ABC) transporter
SAH002_RS02720	COG0512	Glutamine amidotransferase of anthranilate synthase
SAH002_RS02725	COG1268	BioY protein
SAH002_RS02740	COG0183	Belongs to the thiolase family
SAH002_RS02750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAH002_RS02765	COG1940	carbohydrate kinase activity
SAH002_RS02770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAH002_RS02775	COG1217	gtp-binding protein TYPA
SAH002_RS02810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAH002_RS02820	COG0762	integral membrane protein
SAH002_RS02825	COG2302	S4 RNA-binding domain
SAH002_RS02845	COG0494	nUDIX hydrolase
SAH002_RS02850	COG0542	response to heat
SAH002_RS02855	COG4703	Protein of unknown function (DUF1797)
SAH002_RS02860	COG0765	amino acid transport
SAH002_RS02865	COG1126	abc transporter atp-binding protein
SAH002_RS02870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAH002_RS02880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAH002_RS02890	COG1722	exodeoxyribonuclease VII activity
SAH002_RS02900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SAH002_RS02905	COG1438	arginine binding
SAH002_RS02910	COG0497	DNA recombination
SAH002_RS02915	COG1307	EDD domain protein, DegV family
SAH002_RS02920	COG2755	lipolytic protein G-D-S-L family
SAH002_RS02965	COG1078	dGTPase activity
SAH002_RS02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAH002_RS03000	COG2884	Cell division ATP-binding protein ftsE
SAH002_RS03005	COG2177	Part of the ABC transporter FtsEX involved in
SAH002_RS03025	COG1199	ATP-dependent helicase activity
SAH002_RS03025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAH002_RS03030	COG0436	Aminotransferase
SAH002_RS03035	COG0017	Asparaginyl-tRNA synthetase
SAH002_RS03055	COG1660	Displays ATPase and GTPase activities
SAH002_RS03080	COG0254	rRNA binding
SAH002_RS03085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAH002_RS03090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAH002_RS03095	COG0716	FMN binding
SAH002_RS03100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAH002_RS03100	COG1605	Chorismate mutase
SAH002_RS03105	COG0038	chloride channel
SAH002_RS03120	COG0335	large ribosomal subunit rRNA binding
SAH002_RS03155	COG1136	(ABC) transporter
SAH002_RS03170	COG5002	protein histidine kinase activity
SAH002_RS03185	COG0772	Belongs to the SEDS family
SAH002_RS03205	COG0560	Phosphoserine phosphatase
SAH002_RS03220	COG5433	transposase activity
SAH002_RS03225	COG0148	phosphopyruvate hydratase activity
SAH002_RS03245	COG1316	TRANSCRIPTIONal
SAH002_RS03280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAH002_RS03280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAH002_RS03320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAH002_RS03380	COG4695	Portal protein
SAH002_RS03385	COG0740	serine-type endopeptidase activity
SAH002_RS03455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAH002_RS03480	COG3700	Belongs to the class B bacterial acid phosphatase family
SAH002_RS03575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAH002_RS03580	COG4555	ABC transporter
SAH002_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
SAH002_RS03610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAH002_RS03615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAH002_RS03635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SAH002_RS03640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAH002_RS03660	COG3064	Membrane
SAH002_RS03660	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SAH002_RS03675	COG3590	peptidase
SAH002_RS03680	COG3590	peptidase
SAH002_RS03725	COG1136	(ABC) transporter
SAH002_RS03740	COG0586	Pfam SNARE associated Golgi protein
SAH002_RS03745	COG4619	ABC transporter
SAH002_RS03750	COG0390	transport system, permease component
SAH002_RS03760	COG0583	DNA-binding transcription factor activity
SAH002_RS03770	COG5433	transposase activity
SAH002_RS03785	COG2211	Major facilitator Superfamily
SAH002_RS03795	COG3250	beta-galactosidase activity
SAH002_RS03800	COG2186	Transcriptional regulator
SAH002_RS03805	COG0800	Aldolase
SAH002_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
SAH002_RS03840	COG1609	Transcriptional regulator
SAH002_RS03855	COG0438	transferase activity, transferring glycosyl groups
SAH002_RS03880	COG0765	amino acid transport
SAH002_RS03885	COG0765	amino acid transport
SAH002_RS03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAH002_RS03895	COG1126	abc transporter atp-binding protein
SAH002_RS03900	COG0745	RESPONSE REGULATOR receiver
SAH002_RS03905	COG5002	protein histidine kinase activity
SAH002_RS03910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAH002_RS03915	COG2832	Protein of unknown function (DUF454)
SAH002_RS03925	COG1196	nuclear chromosome segregation
SAH002_RS03930	COG0561	phosphatase activity
SAH002_RS03935	COG0561	phosphatase activity
SAH002_RS03940	COG0552	protein localization to endoplasmic reticulum
SAH002_RS03945	COG3689	TIGRFAM TIGR03943 family protein
SAH002_RS03950	COG0701	Predicted permease
SAH002_RS03965	COG2183	response to ionizing radiation
SAH002_RS03970	COG3091	SprT-like family
SAH002_RS03975	COG1983	PspC domain protein
SAH002_RS04010	COG0826	peptidase U32
SAH002_RS04015	COG4443	Transcriptional Coactivator p15 (PC4)
SAH002_RS04025	COG1914	H( )-stimulated, divalent metal cation uptake system
SAH002_RS04040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAH002_RS04040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAH002_RS04065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAH002_RS04090	COG1164	Oligoendopeptidase f
SAH002_RS04100	COG0772	Belongs to the SEDS family
SAH002_RS04120	COG0768	penicillin binding
SAH002_RS04135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAH002_RS04140	COG2223	nitrite transmembrane transporter activity
SAH002_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAH002_RS04170	COG2011	ABC-type metal ion transport system permease component
SAH002_RS04175	COG1464	Belongs to the NlpA lipoprotein family
SAH002_RS04180	COG0513	Belongs to the DEAD box helicase family
SAH002_RS04190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAH002_RS04195	COG0204	Acyl-transferase
SAH002_RS04200	COG1555	photosystem II stabilization
SAH002_RS04200	COG1596	polysaccharide export
SAH002_RS04205	COG2333	competence protein COMEC
SAH002_RS04205	COG0658	competence protein
SAH002_RS04210	COG0561	phosphatase activity
SAH002_RS04215	COG1609	Transcriptional regulator
SAH002_RS04220	COG0657	acetylesterase activity
SAH002_RS04225	COG2226	methyltransferase
SAH002_RS04235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAH002_RS04240	COG3711	transcriptional antiterminator
SAH002_RS04245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS04245	COG1263	PTS System
SAH002_RS04245	COG2190	(PTS) system
SAH002_RS04255	COG3835	regulator
SAH002_RS04260	COG1929	Belongs to the glycerate kinase type-1 family
SAH002_RS04265	COG2610	gluconate transmembrane transporter activity
SAH002_RS04275	COG1846	Transcriptional regulator
SAH002_RS04290	COG0363	glucosamine-6-phosphate deaminase activity
SAH002_RS04295	COG0435	Glutathione S-transferase
SAH002_RS04300	COG1187	pseudouridine synthase activity
SAH002_RS04320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAH002_RS04325	COG4122	O-methyltransferase activity
SAH002_RS04335	COG4894	glucomannan catabolic process
SAH002_RS04350	COG1442	glycosyl transferase family 8
SAH002_RS04365	COG1476	TRANSCRIPTIONal
SAH002_RS04380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAH002_RS04385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAH002_RS04390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAH002_RS04405	COG1012	belongs to the aldehyde dehydrogenase family
SAH002_RS04410	COG0726	polysaccharide deacetylase
SAH002_RS04425	COG1956	GAF domain-containing protein
SAH002_RS04430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAH002_RS04440	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SAH002_RS04440	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SAH002_RS04470	COG4721	ABC-type cobalt transport system, permease component
SAH002_RS04475	COG1122	ATPase activity
SAH002_RS04485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAH002_RS04515	COG4109	DRTGG domain
SAH002_RS04520	COG0024	Methionine aminopeptidase
SAH002_RS04530	COG2246	polysaccharide biosynthetic process
SAH002_RS04535	COG4708	membrane
SAH002_RS04545	COG1597	lipid kinase activity
SAH002_RS04550	COG1523	belongs to the glycosyl hydrolase 13 family
SAH002_RS04565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SAH002_RS04650	COG2321	neutral zinc metallopeptidase
SAH002_RS04675	COG0488	(ABC) transporter
SAH002_RS04680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAH002_RS04685	COG0022	dehydrogenase e1 component
SAH002_RS04685	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAH002_RS04690	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAH002_RS04700	COG0095	Lipoate-protein ligase
SAH002_RS04705	COG3442	glutamine amidotransferase
SAH002_RS04710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAH002_RS04715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAH002_RS04740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAH002_RS04750	COG0647	UMP catabolic process
SAH002_RS04760	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SAH002_RS04765	COG1518	maintenance of DNA repeat elements
SAH002_RS04770	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SAH002_RS04785	COG0481	GTPase activity
SAH002_RS04795	COG5433	transposase activity
SAH002_RS04810	COG1418	mRNA catabolic process
SAH002_RS04815	COG0456	acetyltransferase
SAH002_RS04825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAH002_RS04840	COG5433	transposase activity
SAH002_RS04885	COG0791	NLP P60 protein
SAH002_RS04885	COG0741	lytic transglycosylase activity
SAH002_RS04915	COG2946	Replication initiation factor
SAH002_RS04920	COG1674	ftsk spoiiie
SAH002_RS04940	COG1131	(ABC) transporter
SAH002_RS04945	COG1725	Transcriptional regulator
SAH002_RS04955	COG0205	6-phosphofructokinase activity
SAH002_RS04960	COG0469	pyruvate kinase activity
SAH002_RS04975	COG5433	transposase activity
SAH002_RS04980	COG2824	Alkylphosphonate utilization operon protein PhnA
SAH002_RS04985	COG0765	amino acid transport
SAH002_RS04990	COG1126	abc transporter atp-binding protein
SAH002_RS05005	COG1072	(Pantothenic acid kinase))
SAH002_RS05010	COG2813	Specifically methylates the guanine in position
SAH002_RS05020	COG1744	ABC transporter substrate-binding protein PnrA-like
SAH002_RS05025	COG3845	ABC transporter
SAH002_RS05035	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAH002_RS05055	COG3764	Sortase (surface protein transpeptidase)
SAH002_RS05060	COG0346	lactoylglutathione lyase activity
SAH002_RS05090	COG5433	transposase activity
SAH002_RS05095	COG2188	Transcriptional regulator
SAH002_RS05110	COG1464	Belongs to the NlpA lipoprotein family
SAH002_RS05125	COG1136	(ABC) transporter
SAH002_RS05135	COG0745	RESPONSE REGULATOR receiver
SAH002_RS05140	COG5002	protein histidine kinase activity
SAH002_RS05145	COG4974	Belongs to the 'phage' integrase family
SAH002_RS05150	COG4166	transmembrane transport
SAH002_RS05165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAH002_RS05170	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SAH002_RS05175	COG5002	protein histidine kinase activity
SAH002_RS05180	COG0745	RESPONSE REGULATOR receiver
SAH002_RS05190	COG0704	Plays a role in the regulation of phosphate uptake
SAH002_RS05195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAH002_RS05200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAH002_RS05205	COG0581	inorganic phosphate transmembrane transporter activity
SAH002_RS05210	COG0573	inorganic phosphate transmembrane transporter activity
SAH002_RS05220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SAH002_RS05220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAH002_RS05225	COG0483	inositol monophosphate 1-phosphatase activity
SAH002_RS05240	COG0196	riboflavin kinase activity
SAH002_RS05245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAH002_RS05275	COG1136	(ABC) transporter
SAH002_RS05280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAH002_RS05285	COG0758	DNA mediated transformation
SAH002_RS05290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAH002_RS05295	COG4604	ABC transporter, ATP-binding protein
SAH002_RS05300	COG4605	iron ion homeostasis
SAH002_RS05305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAH002_RS05310	COG0110	maltose O-acetyltransferase activity
SAH002_RS05320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAH002_RS05325	COG1376	ErfK ybiS ycfS ynhG family protein
SAH002_RS05330	COG1966	Carbon starvation protein
SAH002_RS05335	COG3279	Response regulator of the LytR AlgR family
SAH002_RS05340	COG3275	phosphorelay sensor kinase activity
SAH002_RS05375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAH002_RS05380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SAH002_RS05395	COG0488	(ABC) transporter
SAH002_RS05405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAH002_RS05410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SAH002_RS05450	COG0095	Lipoate-protein ligase
SAH002_RS05460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAH002_RS05465	COG4684	Psort location CytoplasmicMembrane, score
SAH002_RS05470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAH002_RS05480	COG2801	Transposase and inactivated derivatives
SAH002_RS05490	COG1132	(ABC) transporter
SAH002_RS05520	COG2890	protein-(glutamine-N5) methyltransferase activity
SAH002_RS05535	COG1942	4-Oxalocrotonate Tautomerase
SAH002_RS05550	COG0431	NADPH-dependent FMN reductase
SAH002_RS05550	COG3976	FMN-binding domain protein
SAH002_RS05550	COG1053	succinate dehydrogenase
SAH002_RS05560	COG2233	PERMEase
SAH002_RS05575	COG0477	Major facilitator Superfamily
SAH002_RS05590	COG4221	oxidoreductase activity
SAH002_RS05595	COG0280	phosphate acetyltransferase
SAH002_RS05600	COG0564	pseudouridine synthase activity
SAH002_RS05610	COG2357	RelA SpoT domain protein
SAH002_RS05625	COG1104	cysteine desulfurase activity
SAH002_RS05645	COG0628	permease
SAH002_RS05660	COG0561	phosphatase activity
SAH002_RS05670	COG0038	chloride channel
SAH002_RS05680	COG1177	transmembrane transport
SAH002_RS05685	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAH002_RS05695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAH002_RS05700	COG5433	transposase activity
SAH002_RS05705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAH002_RS05725	COG0285	dihydrofolate synthase activity
SAH002_RS05730	COG2962	Rard protein
SAH002_RS05745	COG0726	polysaccharide deacetylase
SAH002_RS05750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAH002_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
SAH002_RS05855	COG1115	amino acid carrier protein
SAH002_RS05860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAH002_RS05870	COG1346	cytolysis
SAH002_RS05885	COG0539	negative regulation of cytoplasmic translation
SAH002_RS05905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAH002_RS05915	COG0187	DNA topoisomerase II activity
SAH002_RS05920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SAH002_RS05925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAH002_RS05935	COG1083	cytidylyl-transferase
SAH002_RS05935	COG2755	lipolytic protein G-D-S-L family
SAH002_RS05950	COG2089	acid synthase
SAH002_RS05965	COG1442	glycosyl transferase family 8
SAH002_RS05965	COG1216	Glycosyl transferase, family 2
SAH002_RS05970	COG1442	glycosyl transferase family 8
SAH002_RS05970	COG1216	Glycosyl transferase, family 2
SAH002_RS05985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAH002_RS05990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAH002_RS06010	COG1316	TRANSCRIPTIONal
SAH002_RS06035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAH002_RS06070	COG5433	transposase activity
SAH002_RS06075	COG3842	ATPase activity
SAH002_RS06090	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAH002_RS06095	COG3527	Alpha-acetolactate decarboxylase
SAH002_RS06100	COG0028	Belongs to the TPP enzyme family
SAH002_RS06105	COG0457	Tetratricopeptide repeat
SAH002_RS06110	COG0628	permease
SAH002_RS06120	COG1051	belongs to the nudix hydrolase family
SAH002_RS06125	COG5492	domain, Protein
SAH002_RS06130	COG5433	transposase activity
SAH002_RS06140	COG1088	dTDP-glucose 4,6-dehydratase activity
SAH002_RS06145	COG0135	phosphoribosylanthranilate isomerase activity
SAH002_RS06155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SAH002_RS06160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAH002_RS06170	COG2384	SAM-dependent methyltransferase
SAH002_RS06185	COG5433	transposase activity
SAH002_RS06195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAH002_RS06195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAH002_RS06200	COG0300	oxidoreductase activity
SAH002_RS06215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAH002_RS06235	COG1523	belongs to the glycosyl hydrolase 13 family
SAH002_RS06245	COG1573	uracil-dna glycosylase
SAH002_RS06250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAH002_RS06275	COG0534	Mate efflux family protein
SAH002_RS06310	COG2801	Transposase and inactivated derivatives
SAH002_RS06325	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAH002_RS06330	COG5433	transposase activity
SAH002_RS06335	COG5433	transposase activity
SAH002_RS06360	COG2176	DNA-directed DNA polymerase activity
SAH002_RS06370	COG4974	Belongs to the 'phage' integrase family
SAH002_RS06380	COG1396	sequence-specific DNA binding
SAH002_RS06385	COG3843	relaxase mobilization nuclease domain protein
SAH002_RS06405	COG2801	Transposase and inactivated derivatives
SAH002_RS06435	COG2217	Heavy metal translocating P-type atpase
SAH002_RS06440	COG2217	Heavy metal translocating P-type atpase
SAH002_RS06480	COG1388	LysM domain
SAH002_RS06480	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAH002_RS06495	COG0640	Transcriptional regulator
SAH002_RS06500	COG2217	Heavy metal translocating P-type atpase
SAH002_RS06515	COG0842	Transport permease protein
SAH002_RS06520	COG1131	(ABC) transporter
SAH002_RS06525	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAH002_RS06530	COG0798	PFAM Bile acid sodium symporter
SAH002_RS06605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAH002_RS06635	COG1129	ABC transporter
SAH002_RS06640	COG1132	(ABC) transporter
SAH002_RS06645	COG1132	(ABC) transporter
SAH002_RS06680	COG2198	Histidine kinase
SAH002_RS06680	COG0643	Histidine kinase
SAH002_RS06680	COG0784	Response regulator, receiver
SAH002_RS06715	COG0551	DNA topoisomerase type I activity
SAH002_RS06715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAH002_RS06875	COG0270	DNA (cytosine-5-)-methyltransferase activity
SAH002_RS06940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAH002_RS06950	COG3425	synthase
SAH002_RS06965	COG1272	protein, Hemolysin III
SAH002_RS07010	COG0745	RESPONSE REGULATOR receiver
SAH002_RS07015	COG2357	RelA SpoT domain protein
SAH002_RS07020	COG1132	(ABC) transporter
SAH002_RS07035	COG0737	Belongs to the 5'-nucleotidase family
SAH002_RS07040	COG0242	peptide deformylase activity
SAH002_RS07045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAH002_RS07055	COG1132	(ABC) transporter
SAH002_RS07070	COG0488	(ABC) transporter
SAH002_RS07100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAH002_RS07100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAH002_RS07100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAH002_RS07105	COG1105	Belongs to the carbohydrate kinase PfkB family
SAH002_RS07110	COG1349	DNA-binding transcription factor activity
SAH002_RS07115	COG1388	LysM domain
SAH002_RS07115	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAH002_RS07165	COG1837	Belongs to the UPF0109 family
SAH002_RS07170	COG0228	four-way junction DNA binding
SAH002_RS07175	COG0577	efflux transmembrane transporter activity
SAH002_RS07180	COG1136	(ABC) transporter
SAH002_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SAH002_RS07195	COG0505	Belongs to the CarA family
SAH002_RS07205	COG0564	pseudouridine synthase activity
SAH002_RS07215	COG0583	DNA-binding transcription factor activity
SAH002_RS07220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SAH002_RS07245	COG1104	cysteine desulfurase activity
SAH002_RS07255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAH002_RS07280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAH002_RS07285	COG1368	sulfuric ester hydrolase activity
SAH002_RS07290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAH002_RS07300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAH002_RS07330	COG2244	polysaccharide biosynthetic process
SAH002_RS07340	COG1120	ATPase activity
SAH002_RS07345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAH002_RS07350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAH002_RS07355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAH002_RS07370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAH002_RS07375	COG1253	flavin adenine dinucleotide binding
SAH002_RS07380	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAH002_RS07385	COG1242	4 iron, 4 sulfur cluster binding
SAH002_RS07390	COG5433	transposase activity
SAH002_RS07395	COG0671	phosphoesterase, PA-phosphatase related
SAH002_RS07400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAH002_RS07435	COG0297	glycogen (starch) synthase activity
SAH002_RS07475	COG3475	LICD family
SAH002_RS07490	COG0463	Glycosyl transferase, family 2
SAH002_RS07495	COG1215	transferase activity, transferring glycosyl groups
SAH002_RS07505	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAH002_RS07510	COG2151	metal-sulfur cluster biosynthetic enzyme
SAH002_RS07515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAH002_RS07520	COG0358	DNA primase activity
SAH002_RS07525	COG1970	mechanosensitive ion channel activity
SAH002_RS07540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAH002_RS07545	COG0004	ammonium transporteR
SAH002_RS07555	COG1054	Belongs to the UPF0176 family
SAH002_RS07565	COG2271	Major facilitator Superfamily
SAH002_RS07570	COG0058	SHG alpha-glucan phosphorylase activity
SAH002_RS07575	COG1640	4-alpha-glucanotransferase
SAH002_RS07580	COG1609	Transcriptional regulator
SAH002_RS07590	COG1175	transmembrane transport
SAH002_RS07595	COG3833	ABC-type maltose transport systems, permease component
SAH002_RS07600	COG3104	oligopeptide transport
SAH002_RS07620	COG0438	transferase activity, transferring glycosyl groups
SAH002_RS07650	COG0765	amino acid transport
SAH002_RS07655	COG1126	abc transporter atp-binding protein
SAH002_RS07680	COG2309	aminopeptidase activity
SAH002_RS07690	COG0154	amidase activity
SAH002_RS07695	COG1187	pseudouridine synthase activity
SAH002_RS07700	COG0656	L-ascorbic acid biosynthetic process
SAH002_RS07705	COG0778	Nitroreductase
SAH002_RS07710	COG0346	lactoylglutathione lyase activity
SAH002_RS07715	COG0463	Glycosyl transferase, family 2
SAH002_RS07720	COG1113	amino acid transport
SAH002_RS07725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAH002_RS07730	COG0557	exoribonuclease II activity
SAH002_RS07740	COG2814	Major facilitator Superfamily
SAH002_RS07750	COG1131	(ABC) transporter
SAH002_RS07760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAH002_RS07765	COG1396	sequence-specific DNA binding
SAH002_RS07805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SAH002_RS07810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAH002_RS07830	COG1702	phosphate starvation-inducible protein PhoH
SAH002_RS07855	COG0233	cytoplasmic translational termination
SAH002_RS07870	COG0444	Belongs to the ABC transporter superfamily
SAH002_RS07875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAH002_RS07880	COG0601	transmembrane transport
SAH002_RS07885	COG0747	negative chemotaxis
SAH002_RS07890	COG0081	regulation of translation
SAH002_RS07910	COG1473	amidohydrolase
SAH002_RS07915	COG0583	DNA-binding transcription factor activity
SAH002_RS07930	COG2801	Transposase and inactivated derivatives
SAH002_RS07935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAH002_RS07945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAH002_RS07970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAH002_RS08000	COG0673	inositol 2-dehydrogenase activity
SAH002_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
SAH002_RS08075	COG1114	Component of the transport system for branched-chain amino acids
SAH002_RS08080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAH002_RS08080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAH002_RS08095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAH002_RS08105	COG0708	Exodeoxyribonuclease III
SAH002_RS08110	COG1393	Belongs to the ArsC family
SAH002_RS08115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAH002_RS08120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAH002_RS08150	COG0470	DNA polymerase III
SAH002_RS08165	COG0517	IMP dehydrogenase activity
SAH002_RS08185	COG0559	Belongs to the binding-protein-dependent transport system permease family
SAH002_RS08205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAH002_RS08210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAH002_RS08220	COG0531	amino acid
SAH002_RS08225	COG0569	domain protein
SAH002_RS08230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAH002_RS08240	COG1187	pseudouridine synthase activity
SAH002_RS08290	COG1827	regulation of RNA biosynthetic process
SAH002_RS08305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAH002_RS08310	COG1254	Belongs to the acylphosphatase family
SAH002_RS08320	COG0765	amino acid transport
SAH002_RS08325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAH002_RS08340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SAH002_RS08370	COG1484	DNA-dependent DNA replication
SAH002_RS08385	COG5002	protein histidine kinase activity
SAH002_RS08390	COG0745	RESPONSE REGULATOR receiver
SAH002_RS08405	COG1704	LemA family
SAH002_RS08415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAH002_RS08420	COG0569	domain protein
SAH002_RS08445	COG1114	Component of the transport system for branched-chain amino acids
SAH002_RS08450	COG1063	alcohol dehydrogenase
SAH002_RS08475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAH002_RS08480	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAH002_RS08485	COG0217	transcriptional regulatory protein
SAH002_RS08490	COG2376	Dihydroxyacetone kinase
SAH002_RS08495	COG1309	transcriptional regulator
SAH002_RS08500	COG2376	Dihydroxyacetone kinase
SAH002_RS08505	COG1461	Dihydroxyacetone kinase
SAH002_RS08510	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAH002_RS08515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAH002_RS08525	COG0789	Transcriptional regulator
SAH002_RS08540	COG2226	methyltransferase
SAH002_RS08545	COG0799	negative regulation of ribosome biogenesis
SAH002_RS08555	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAH002_RS08560	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAH002_RS08565	COG1534	Rna-binding protein
SAH002_RS08570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAH002_RS08575	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAH002_RS08600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAH002_RS08600	COG0574	Belongs to the PEP-utilizing enzyme family
SAH002_RS08610	COG0517	IMP dehydrogenase activity
SAH002_RS08620	COG1335	isochorismatase
SAH002_RS08625	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SAH002_RS08630	COG0436	Aminotransferase
SAH002_RS08635	COG0589	response to stress
SAH002_RS08640	COG0561	phosphatase activity
SAH002_RS08645	COG0252	asparaginase activity
SAH002_RS08655	COG4989	oxidoreductase activity
SAH002_RS08660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAH002_RS08665	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAH002_RS08665	COG3942	CHAP domain
SAH002_RS08675	COG0736	holo-[acyl-carrier-protein] synthase activity
SAH002_RS08680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SAH002_RS08690	COG1482	cell wall glycoprotein biosynthetic process
SAH002_RS08695	COG1940	carbohydrate kinase activity
SAH002_RS08700	COG1263	PTS System
SAH002_RS08700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS08700	COG2190	(PTS) system
SAH002_RS08705	COG1621	beta-fructofuranosidase activity
SAH002_RS08710	COG1609	Transcriptional regulator
SAH002_RS08715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAH002_RS08725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAH002_RS08745	COG2131	deaminase
SAH002_RS08760	COG2814	Major facilitator Superfamily
SAH002_RS08785	COG0629	single-stranded DNA binding
SAH002_RS08790	COG0360	Binds together with S18 to 16S ribosomal RNA
SAH002_RS08795	COG1194	a g-specific adenine glycosylase
SAH002_RS08805	COG3118	belongs to the thioredoxin family
SAH002_RS08835	COG0681	Belongs to the peptidase S26 family
SAH002_RS08840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAH002_RS08855	COG1882	Formate acetyltransferase
SAH002_RS08860	COG3576	pyridoxamine 5-phosphate
SAH002_RS08865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAH002_RS08880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAH002_RS08890	COG2814	Major facilitator Superfamily
SAH002_RS08895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAH002_RS08910	COG0142	geranyltranstransferase activity
SAH002_RS08915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAH002_RS08920	COG4988	ABC transporter
SAH002_RS08925	COG1294	oxidase, subunit
SAH002_RS08930	COG1271	oxidase subunit
SAH002_RS08935	COG1252	NADH dehydrogenase
SAH002_RS08950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAH002_RS08955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAH002_RS08960	COG0789	Transcriptional regulator
SAH002_RS08975	COG2081	HI0933 family
SAH002_RS09000	COG0456	acetyltransferase
SAH002_RS09005	COG1214	PFAM Peptidase M22, glycoprotease
SAH002_RS09020	COG3942	CHAP domain
SAH002_RS09025	COG0174	glutamine synthetase
SAH002_RS09030	COG0789	Transcriptional regulator
SAH002_RS09045	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAH002_RS09070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAH002_RS09120	COG0084	hydrolase, TatD family'
SAH002_RS09145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAH002_RS09150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAH002_RS09155	COG1696	Membrane protein involved in D-alanine export
SAH002_RS09175	COG0745	RESPONSE REGULATOR receiver
SAH002_RS09185	COG3314	Sporulation integral membrane protein YlbJ
SAH002_RS09200	COG4175	Glycine betaine
SAH002_RS09200	COG3448	diguanylate cyclase activity
SAH002_RS09205	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SAH002_RS09225	COG1070	Carbohydrate kinase
SAH002_RS09235	COG3775	system Galactitol-specific IIC component
SAH002_RS09240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAH002_RS09250	COG1609	Transcriptional regulator
SAH002_RS09300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SAH002_RS09330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SAH002_RS09335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAH002_RS09340	COG1428	Deoxynucleoside kinase
SAH002_RS09350	COG0542	response to heat
SAH002_RS09355	COG4463	regulation of RNA biosynthetic process
SAH002_RS09365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAH002_RS09375	COG0450	alkyl hydroperoxide reductase
SAH002_RS09390	COG0025	NhaP-type Na H and K H
SAH002_RS09400	COG1619	proteins homologs of microcin C7 resistance protein MccF
SAH002_RS09405	COG3590	peptidase
SAH002_RS09430	COG1609	Transcriptional regulator
SAH002_RS09440	COG3716	PTS system mannose fructose sorbose family IID component
SAH002_RS09445	COG3715	PTS system
SAH002_RS09450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS09455	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAH002_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
SAH002_RS09500	COG2176	DNA-directed DNA polymerase activity
SAH002_RS09505	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAH002_RS09505	COG1388	LysM domain
SAH002_RS09520	COG4589	Belongs to the CDS family
SAH002_RS09525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAH002_RS09530	COG1862	Preprotein translocase
SAH002_RS09545	COG3493	citrate carrier protein
SAH002_RS09550	COG3290	protein histidine kinase activity
SAH002_RS09555	COG4565	transcriptional regulatory protein
SAH002_RS09560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAH002_RS09570	COG3842	ATPase activity
SAH002_RS09645	COG1490	D-aminoacyl-tRNA deacylase activity
SAH002_RS09655	COG0737	Belongs to the 5'-nucleotidase family
SAH002_RS09665	COG1363	Peptidase, m42
SAH002_RS09690	COG2972	Histidine kinase
SAH002_RS09695	COG3716	PTS system mannose fructose sorbose family IID component
SAH002_RS09700	COG3715	PTS system
SAH002_RS09725	COG1131	(ABC) transporter
SAH002_RS09735	COG3279	Response regulator of the LytR AlgR family
SAH002_RS09745	COG1263	PTS System
SAH002_RS09745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAH002_RS09745	COG2190	(PTS) system
SAH002_RS09750	COG5002	protein histidine kinase activity
SAH002_RS09755	COG0745	RESPONSE REGULATOR receiver
SAH002_RS09765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAH002_RS09770	COG0581	inorganic phosphate transmembrane transporter activity
SAH002_RS09775	COG0573	inorganic phosphate transmembrane transporter activity
SAH002_RS09790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAH002_RS09805	COG0789	Transcriptional regulator
SAH002_RS09825	COG0456	acetyltransferase
SAH002_RS09830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAH002_RS09840	COG0582	viral genome integration into host DNA
SAH002_RS09880	COG0433	COG0433 Predicted ATPase
SAH002_RS09900	COG4115	mRNA cleavage
SAH002_RS09945	COG1674	ftsk spoiiie
SAH002_RS09980	COG1914	H( )-stimulated, divalent metal cation uptake system
SAH002_RS09990	COG1131	(ABC) transporter
SAH002_RS10025	COG1131	(ABC) transporter
SAH002_RS10035	COG1396	sequence-specific DNA binding
SAH002_RS10040	COG2801	Transposase and inactivated derivatives
SAH002_RS10055	COG1694	Mazg nucleotide pyrophosphohydrolase
SAH002_RS10085	COG0371	Dehydrogenase
SAH002_RS10095	COG0646	methionine synthase
SAH002_RS10095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAH002_RS10100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SAH002_RS10110	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SAH002_RS10125	COG0745	RESPONSE REGULATOR receiver
SAH002_RS10130	COG2770	Histidine kinase
SAH002_RS10130	COG2205	protein histidine kinase activity
SAH002_RS10140	COG0495	leucyl-tRNA aminoacylation
SAH002_RS10145	COG2814	Major facilitator Superfamily
SAH002_RS10150	COG4667	esterase of the alpha-beta hydrolase superfamily
SAH002_RS10155	COG1442	glycosyl transferase family 8
SAH002_RS10160	COG1442	glycosyl transferase family 8
SAH002_RS10180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAH002_RS10185	COG0564	pseudouridine synthase activity
SAH002_RS10205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAH002_RS10210	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SAH002_RS10230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAH002_RS10235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SAH002_RS10235	COG1116	anion transmembrane transporter activity
SAH002_RS10240	COG4120	Belongs to the binding-protein-dependent transport system permease family
SAH002_RS10250	COG0561	phosphatase activity
SAH002_RS10255	COG2514	catechol 2,3-dioxygenase activity
SAH002_RS10265	COG0602	queuosine metabolic process
SAH002_RS10285	COG1328	CTP reductase activity
SAH002_RS10305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAH002_RS10315	COG1393	Belongs to the ArsC family
SAH002_RS10320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SAH002_RS10330	COG2818	Glycosylase
SAH002_RS10345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SAH002_RS10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAH002_RS10380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAH002_RS10390	COG0124	histidyl-tRNA synthetase
SAH002_RS10400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAH002_RS10410	COG0745	RESPONSE REGULATOR receiver
SAH002_RS10415	COG5002	protein histidine kinase activity
SAH002_RS10420	COG1288	antiporter activity
SAH002_RS10430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAH002_RS10435	COG3852	Histidine kinase
SAH002_RS10440	COG0784	Response regulator, receiver
SAH002_RS10445	COG0517	IMP dehydrogenase activity
SAH002_RS10445	COG1125	glycine betaine transport
SAH002_RS10450	COG1174	glycine betaine transport
SAH002_RS10455	COG2801	Transposase and inactivated derivatives
SAH002_RS10465	COG0392	lysyltransferase activity
SAH002_RS10465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAH002_RS10475	COG3759	membrane
SAH002_RS10505	COG0305	Participates in initiation and elongation during chromosome replication
SAH002_RS10520	COG0445	tRNA wobble uridine modification
SAH002_RS10525	COG2095	MarC family integral membrane protein
SAH002_RS10530	COG0482	sulfurtransferase activity
SAH002_RS10535	COG1760	l-serine dehydratase
SAH002_RS10540	COG1760	l-serine dehydratase
SAH002_RS10545	COG0741	lytic transglycosylase activity
SAH002_RS10570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAH002_RS10575	COG0612	Peptidase, M16
SAH002_RS10580	COG0612	Peptidase, M16
SAH002_RS10585	COG2501	S4 domain
SAH002_RS10605	COG0516	GMP reductase activity
SAH002_RS10605	COG0517	IMP dehydrogenase activity
SAH002_RS10615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAH002_RS10630	COG0454	-acetyltransferase
SAH002_RS10635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAH002_RS10660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAH002_RS10665	COG0488	(ABC) transporter
SAH002_RS10670	COG4485	Bacterial membrane protein, YfhO
SAH002_RS10690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SAH002_RS10695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAH002_RS10700	COG1475	DNA binding