locus-tag	class	description
SAHN016_RS00010	COG0592	DNA-directed DNA polymerase activity
SAHN016_RS00015	COG1597	lipid kinase activity
SAHN016_RS00025	COG0012	GTP binding
SAHN016_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SAHN016_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAHN016_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAHN016_RS00255	COG0436	Aminotransferase
SAHN016_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAHN016_RS00285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAHN016_RS00300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SAHN016_RS00335	COG1175	transmembrane transport
SAHN016_RS00340	COG0395	ABC-type sugar transport system, permease component
SAHN016_RS00355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAHN016_RS00365	COG3458	cephalosporin-C deacetylase activity
SAHN016_RS00380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAHN016_RS00395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAHN016_RS00410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAHN016_RS00420	COG2755	lipolytic protein G-D-S-L family
SAHN016_RS00420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAHN016_RS00425	COG1012	belongs to the aldehyde dehydrogenase family
SAHN016_RS00425	COG1454	alcohol dehydrogenase
SAHN016_RS00430	COG1064	alcohol dehydrogenase
SAHN016_RS00440	COG0534	Mate efflux family protein
SAHN016_RS00550	COG0201	protein transport
SAHN016_RS00565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAHN016_RS00575	COG0202	RNA polymerase activity
SAHN016_RS00680	COG3344	reverse transcriptase
SAHN016_RS00700	COG3344	reverse transcriptase
SAHN016_RS00720	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAHN016_RS00735	COG0443	Heat shock 70 kDa protein
SAHN016_RS00745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAHN016_RS00755	COG0351	phosphomethylpyrimidine kinase
SAHN016_RS00760	COG4720	Psort location CytoplasmicMembrane, score
SAHN016_RS00770	COG0668	transmembrane transport
SAHN016_RS00800	COG0756	dUTP diphosphatase activity
SAHN016_RS00815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAHN016_RS00830	COG1879	ABC-type sugar transport system periplasmic component
SAHN016_RS00835	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAHN016_RS00850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAHN016_RS00855	COG1609	Transcriptional regulator
SAHN016_RS00860	COG0577	efflux transmembrane transporter activity
SAHN016_RS00865	COG1136	(ABC) transporter
SAHN016_RS00870	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS00875	COG5002	protein histidine kinase activity
SAHN016_RS00890	COG0191	fructose-bisphosphate aldolase activity
SAHN016_RS00910	COG1461	Dihydroxyacetone kinase
SAHN016_RS00940	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAHN016_RS00945	COG5002	protein histidine kinase activity
SAHN016_RS00950	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS00965	COG1126	abc transporter atp-binding protein
SAHN016_RS00970	COG0765	amino acid transport
SAHN016_RS00990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAHN016_RS01000	COG0719	Fe-S assembly protein
SAHN016_RS01005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAHN016_RS01015	COG0719	Fe-S assembly protein
SAHN016_RS01020	COG1686	Belongs to the peptidase S11 family
SAHN016_RS01025	COG1686	Belongs to the peptidase S11 family
SAHN016_RS01030	COG4166	transmembrane transport
SAHN016_RS01035	COG0601	transmembrane transport
SAHN016_RS01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAHN016_RS01045	COG0444	Belongs to the ABC transporter superfamily
SAHN016_RS01050	COG4608	Belongs to the ABC transporter superfamily
SAHN016_RS01090	COG1121	(ABC) transporter
SAHN016_RS01095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAHN016_RS01110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAHN016_RS01110	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAHN016_RS01130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAHN016_RS01175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAHN016_RS01180	COG1363	Peptidase, m42
SAHN016_RS01195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAHN016_RS01200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAHN016_RS01215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAHN016_RS01235	COG1346	cytolysis
SAHN016_RS01245	COG0601	transmembrane transport
SAHN016_RS01250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAHN016_RS01255	COG1122	ATPase activity
SAHN016_RS01265	COG1263	PTS System
SAHN016_RS01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS01270	COG0366	Alpha amylase catalytic
SAHN016_RS01275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAHN016_RS01290	COG3959	Transketolase, thiamine diphosphate binding domain
SAHN016_RS01295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SAHN016_RS01300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAHN016_RS01320	COG1045	serine acetyltransferase
SAHN016_RS01335	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAHN016_RS01355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAHN016_RS01365	COG4974	Belongs to the 'phage' integrase family
SAHN016_RS01470	COG1396	sequence-specific DNA binding
SAHN016_RS01475	COG2814	Major facilitator Superfamily
SAHN016_RS01485	COG1732	Glycine betaine
SAHN016_RS01620	COG0519	Catalyzes the synthesis of GMP from XMP
SAHN016_RS01665	COG1695	Transcriptional regulator
SAHN016_RS01680	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAHN016_RS01720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAHN016_RS01725	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAHN016_RS01745	COG1131	(ABC) transporter
SAHN016_RS01755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS01755	COG2190	(PTS) system
SAHN016_RS01755	COG1263	PTS System
SAHN016_RS01760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAHN016_RS01780	COG0768	penicillin binding
SAHN016_RS01790	COG0513	Belongs to the DEAD box helicase family
SAHN016_RS01805	COG1126	abc transporter atp-binding protein
SAHN016_RS01815	COG0492	ferredoxin-NADP+ reductase activity
SAHN016_RS01820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAHN016_RS01830	COG3579	cysteine-type endopeptidase activity
SAHN016_RS01835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAHN016_RS01855	COG0116	Belongs to the methyltransferase superfamily
SAHN016_RS01865	COG1854	S-ribosylhomocysteine lyase activity
SAHN016_RS01870	COG4372	Transposase
SAHN016_RS01870	COG1418	mRNA catabolic process
SAHN016_RS01875	COG1131	(ABC) transporter
SAHN016_RS01885	COG4585	Histidine kinase
SAHN016_RS01890	COG2197	response regulator
SAHN016_RS01900	COG0194	GDP metabolic process
SAHN016_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAHN016_RS01915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAHN016_RS01920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAHN016_RS01920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAHN016_RS01930	COG0515	serine threonine protein kinase
SAHN016_RS01930	COG2815	serine threonine protein kinase
SAHN016_RS01940	COG4585	Histidine kinase
SAHN016_RS01945	COG2197	response regulator
SAHN016_RS01955	COG1098	S1 RNA binding domain
SAHN016_RS01960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAHN016_RS01965	COG1349	DNA-binding transcription factor activity
SAHN016_RS01975	COG1447	Phosphotransferase system cellobiose-specific component IIA
SAHN016_RS01985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAHN016_RS01990	COG1882	Formate acetyltransferase
SAHN016_RS02010	COG1739	Uncharacterized protein family UPF0029
SAHN016_RS02015	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAHN016_RS02020	COG1040	competence protein
SAHN016_RS02055	COG0527	aspartate kinase activity
SAHN016_RS02060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAHN016_RS02065	COG1024	Enoyl-CoA hydratase
SAHN016_RS02075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAHN016_RS02085	COG2070	2-Nitropropane dioxygenase
SAHN016_RS02090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SAHN016_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
SAHN016_RS02100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAHN016_RS02115	COG0439	Biotin carboxylase
SAHN016_RS02135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAHN016_RS02150	COG3716	PTS system mannose fructose sorbose family IID component
SAHN016_RS02155	COG3715	PTS system
SAHN016_RS02165	COG0561	phosphatase activity
SAHN016_RS02180	COG2252	PERMEase
SAHN016_RS02185	COG0802	atpase or kinase
SAHN016_RS02195	COG1316	TRANSCRIPTIONal
SAHN016_RS02205	COG0537	adenosine 5'-monophosphoramidase activity
SAHN016_RS02220	COG1131	(ABC) transporter
SAHN016_RS02225	COG4473	ABC transporter
SAHN016_RS02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAHN016_RS02250	COG0195	Participates in both transcription termination and antitermination
SAHN016_RS02255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAHN016_RS02265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SAHN016_RS02270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAHN016_RS02295	COG2860	membrane
SAHN016_RS02305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAHN016_RS02305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAHN016_RS02310	COG1832	CoA-binding protein
SAHN016_RS02330	COG5002	protein histidine kinase activity
SAHN016_RS02350	COG1268	BioY protein
SAHN016_RS02355	COG1234	tRNA 3'-trailer cleavage
SAHN016_RS02370	COG0166	Belongs to the GPI family
SAHN016_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAHN016_RS02380	COG0705	Rhomboid family
SAHN016_RS02380	COG0457	Tetratricopeptide repeat
SAHN016_RS02385	COG1744	ABC transporter substrate-binding protein PnrA-like
SAHN016_RS02390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAHN016_RS02405	COG0706	membrane insertase activity
SAHN016_RS02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAHN016_RS02475	COG2153	protein acetylation
SAHN016_RS02485	COG1442	glycosyl transferase family 8
SAHN016_RS02485	COG1216	Glycosyl transferase, family 2
SAHN016_RS02520	COG2801	Transposase and inactivated derivatives
SAHN016_RS02530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAHN016_RS02540	COG0789	Transcriptional regulator
SAHN016_RS02550	COG0656	L-ascorbic acid biosynthetic process
SAHN016_RS02595	COG2226	methyltransferase
SAHN016_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAHN016_RS02610	COG3414	Phosphotransferase system galactitol-specific IIB component
SAHN016_RS02615	COG3775	system Galactitol-specific IIC component
SAHN016_RS02620	COG0235	Class ii aldolase
SAHN016_RS02630	COG3775	system Galactitol-specific IIC component
SAHN016_RS02635	COG3414	Phosphotransferase system galactitol-specific IIB component
SAHN016_RS02640	COG2207	Transcriptional regulator
SAHN016_RS02650	COG1175	transmembrane transport
SAHN016_RS02655	COG0395	ABC-type sugar transport system, permease component
SAHN016_RS02675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAHN016_RS02680	COG2017	converts alpha-aldose to the beta-anomer
SAHN016_RS02715	COG0673	inositol 2-dehydrogenase activity
SAHN016_RS02725	COG2315	Protein conserved in bacteria
SAHN016_RS02740	COG0742	ribosomal rna small subunit methyltransferase
SAHN016_RS02755	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAHN016_RS02760	COG0737	Belongs to the 5'-nucleotidase family
SAHN016_RS02765	COG4470	Protein conserved in bacteria
SAHN016_RS02780	COG1132	(ABC) transporter
SAHN016_RS02785	COG1132	(ABC) transporter
SAHN016_RS02790	COG0512	Glutamine amidotransferase of anthranilate synthase
SAHN016_RS02800	COG1268	BioY protein
SAHN016_RS02815	COG0183	Belongs to the thiolase family
SAHN016_RS02825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAHN016_RS02840	COG1940	carbohydrate kinase activity
SAHN016_RS02845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAHN016_RS02850	COG1217	gtp-binding protein TYPA
SAHN016_RS02875	COG3344	reverse transcriptase
SAHN016_RS02890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAHN016_RS02900	COG0762	integral membrane protein
SAHN016_RS02905	COG2302	S4 RNA-binding domain
SAHN016_RS02910	COG3599	regulation of cell shape
SAHN016_RS02925	COG0494	nUDIX hydrolase
SAHN016_RS02930	COG0542	response to heat
SAHN016_RS02935	COG4703	Protein of unknown function (DUF1797)
SAHN016_RS02940	COG3344	reverse transcriptase
SAHN016_RS02945	COG0765	amino acid transport
SAHN016_RS02950	COG1126	abc transporter atp-binding protein
SAHN016_RS02955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAHN016_RS02965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAHN016_RS02975	COG1722	exodeoxyribonuclease VII activity
SAHN016_RS02985	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SAHN016_RS02990	COG1438	arginine binding
SAHN016_RS02995	COG0497	DNA recombination
SAHN016_RS03000	COG1307	EDD domain protein, DegV family
SAHN016_RS03005	COG2755	lipolytic protein G-D-S-L family
SAHN016_RS03050	COG1078	dGTPase activity
SAHN016_RS03075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAHN016_RS03085	COG2884	Cell division ATP-binding protein ftsE
SAHN016_RS03090	COG2177	Part of the ABC transporter FtsEX involved in
SAHN016_RS03115	COG3344	reverse transcriptase
SAHN016_RS03120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAHN016_RS03120	COG1199	ATP-dependent helicase activity
SAHN016_RS03125	COG0436	Aminotransferase
SAHN016_RS03130	COG0017	Asparaginyl-tRNA synthetase
SAHN016_RS03150	COG1660	Displays ATPase and GTPase activities
SAHN016_RS03180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAHN016_RS03190	COG0716	FMN binding
SAHN016_RS03195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAHN016_RS03195	COG1605	Chorismate mutase
SAHN016_RS03200	COG0038	chloride channel
SAHN016_RS03205	COG0335	large ribosomal subunit rRNA binding
SAHN016_RS03240	COG1136	(ABC) transporter
SAHN016_RS03255	COG5002	protein histidine kinase activity
SAHN016_RS03270	COG0772	Belongs to the SEDS family
SAHN016_RS03290	COG0560	Phosphoserine phosphatase
SAHN016_RS03305	COG0148	phosphopyruvate hydratase activity
SAHN016_RS03325	COG1316	TRANSCRIPTIONal
SAHN016_RS03360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAHN016_RS03360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAHN016_RS03400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAHN016_RS03420	COG0270	DNA (cytosine-5-)-methyltransferase activity
SAHN016_RS03460	COG4695	Portal protein
SAHN016_RS03465	COG0740	serine-type endopeptidase activity
SAHN016_RS03535	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAHN016_RS03540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAHN016_RS03580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAHN016_RS03585	COG4555	ABC transporter
SAHN016_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
SAHN016_RS03615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAHN016_RS03620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAHN016_RS03640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SAHN016_RS03645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAHN016_RS03665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SAHN016_RS03665	COG3064	Membrane
SAHN016_RS03680	COG3590	peptidase
SAHN016_RS03685	COG3590	peptidase
SAHN016_RS03725	COG1136	(ABC) transporter
SAHN016_RS03740	COG0586	Pfam SNARE associated Golgi protein
SAHN016_RS03745	COG4619	ABC transporter
SAHN016_RS03750	COG0390	transport system, permease component
SAHN016_RS03760	COG0583	DNA-binding transcription factor activity
SAHN016_RS03770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAHN016_RS03775	COG2211	Major facilitator Superfamily
SAHN016_RS03785	COG3250	beta-galactosidase activity
SAHN016_RS03790	COG2186	Transcriptional regulator
SAHN016_RS03795	COG0800	Aldolase
SAHN016_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
SAHN016_RS03835	COG1609	Transcriptional regulator
SAHN016_RS03850	COG0438	transferase activity, transferring glycosyl groups
SAHN016_RS03875	COG0765	amino acid transport
SAHN016_RS03880	COG0765	amino acid transport
SAHN016_RS03885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAHN016_RS03890	COG1126	abc transporter atp-binding protein
SAHN016_RS03895	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS03900	COG5002	protein histidine kinase activity
SAHN016_RS03905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAHN016_RS03910	COG2832	Protein of unknown function (DUF454)
SAHN016_RS03920	COG1196	nuclear chromosome segregation
SAHN016_RS03925	COG0561	phosphatase activity
SAHN016_RS03930	COG0561	phosphatase activity
SAHN016_RS03935	COG0552	protein localization to endoplasmic reticulum
SAHN016_RS03940	COG3344	reverse transcriptase
SAHN016_RS03945	COG3689	TIGRFAM TIGR03943 family protein
SAHN016_RS03950	COG0701	Predicted permease
SAHN016_RS03965	COG2183	response to ionizing radiation
SAHN016_RS03970	COG3091	SprT-like family
SAHN016_RS03975	COG1983	PspC domain protein
SAHN016_RS04015	COG0826	peptidase U32
SAHN016_RS04020	COG4443	Transcriptional Coactivator p15 (PC4)
SAHN016_RS04030	COG1914	H( )-stimulated, divalent metal cation uptake system
SAHN016_RS04045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAHN016_RS04045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAHN016_RS04070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAHN016_RS04095	COG1164	Oligoendopeptidase f
SAHN016_RS04105	COG0772	Belongs to the SEDS family
SAHN016_RS04125	COG0768	penicillin binding
SAHN016_RS04140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAHN016_RS04145	COG2223	nitrite transmembrane transporter activity
SAHN016_RS04170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAHN016_RS04175	COG2011	ABC-type metal ion transport system permease component
SAHN016_RS04180	COG1464	Belongs to the NlpA lipoprotein family
SAHN016_RS04185	COG0513	Belongs to the DEAD box helicase family
SAHN016_RS04195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAHN016_RS04200	COG0204	Acyl-transferase
SAHN016_RS04210	COG2333	competence protein COMEC
SAHN016_RS04210	COG0658	competence protein
SAHN016_RS04215	COG0561	phosphatase activity
SAHN016_RS04220	COG1609	Transcriptional regulator
SAHN016_RS04225	COG0657	acetylesterase activity
SAHN016_RS04230	COG2226	methyltransferase
SAHN016_RS04240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAHN016_RS04245	COG3711	transcriptional antiterminator
SAHN016_RS04250	COG1263	PTS System
SAHN016_RS04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS04255	COG2190	(PTS) system
SAHN016_RS04255	COG1263	PTS System
SAHN016_RS04265	COG3835	regulator
SAHN016_RS04270	COG1929	Belongs to the glycerate kinase type-1 family
SAHN016_RS04275	COG2610	gluconate transmembrane transporter activity
SAHN016_RS04285	COG1846	Transcriptional regulator
SAHN016_RS04300	COG0363	glucosamine-6-phosphate deaminase activity
SAHN016_RS04305	COG0435	Glutathione S-transferase
SAHN016_RS04310	COG1187	pseudouridine synthase activity
SAHN016_RS04330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAHN016_RS04335	COG4122	O-methyltransferase activity
SAHN016_RS04345	COG4894	glucomannan catabolic process
SAHN016_RS04355	COG1811	Na channel or pump
SAHN016_RS04360	COG1442	glycosyl transferase family 8
SAHN016_RS04370	COG1476	TRANSCRIPTIONal
SAHN016_RS04385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAHN016_RS04390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAHN016_RS04395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAHN016_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
SAHN016_RS04415	COG0726	polysaccharide deacetylase
SAHN016_RS04430	COG1956	GAF domain-containing protein
SAHN016_RS04435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAHN016_RS04445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SAHN016_RS04445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SAHN016_RS04475	COG4721	ABC-type cobalt transport system, permease component
SAHN016_RS04480	COG1122	ATPase activity
SAHN016_RS04490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAHN016_RS04520	COG4109	DRTGG domain
SAHN016_RS04525	COG0024	Methionine aminopeptidase
SAHN016_RS04535	COG2246	polysaccharide biosynthetic process
SAHN016_RS04540	COG4708	membrane
SAHN016_RS04550	COG1597	lipid kinase activity
SAHN016_RS04555	COG1523	belongs to the glycosyl hydrolase 13 family
SAHN016_RS04570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SAHN016_RS04655	COG2321	neutral zinc metallopeptidase
SAHN016_RS04680	COG0488	(ABC) transporter
SAHN016_RS04685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAHN016_RS04690	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAHN016_RS04690	COG0022	dehydrogenase e1 component
SAHN016_RS04695	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAHN016_RS04705	COG0095	Lipoate-protein ligase
SAHN016_RS04710	COG3344	reverse transcriptase
SAHN016_RS04715	COG3442	glutamine amidotransferase
SAHN016_RS04720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAHN016_RS04725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAHN016_RS04750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAHN016_RS04760	COG0647	UMP catabolic process
SAHN016_RS04770	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SAHN016_RS04775	COG1518	maintenance of DNA repeat elements
SAHN016_RS04780	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SAHN016_RS04795	COG0481	GTPase activity
SAHN016_RS04805	COG1418	mRNA catabolic process
SAHN016_RS04810	COG0456	acetyltransferase
SAHN016_RS04820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAHN016_RS04845	COG1131	(ABC) transporter
SAHN016_RS04850	COG1725	Transcriptional regulator
SAHN016_RS04860	COG0205	6-phosphofructokinase activity
SAHN016_RS04865	COG0469	pyruvate kinase activity
SAHN016_RS04875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAHN016_RS04880	COG2824	Alkylphosphonate utilization operon protein PhnA
SAHN016_RS04885	COG0765	amino acid transport
SAHN016_RS04890	COG1126	abc transporter atp-binding protein
SAHN016_RS04905	COG1072	(Pantothenic acid kinase))
SAHN016_RS04910	COG2813	Specifically methylates the guanine in position
SAHN016_RS04920	COG1744	ABC transporter substrate-binding protein PnrA-like
SAHN016_RS04925	COG3845	ABC transporter
SAHN016_RS04930	COG4603	Belongs to the binding-protein-dependent transport system permease family
SAHN016_RS04935	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAHN016_RS04955	COG3764	Sortase (surface protein transpeptidase)
SAHN016_RS04960	COG0346	lactoylglutathione lyase activity
SAHN016_RS04990	COG2188	Transcriptional regulator
SAHN016_RS05005	COG1464	Belongs to the NlpA lipoprotein family
SAHN016_RS05020	COG1136	(ABC) transporter
SAHN016_RS05030	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS05035	COG5002	protein histidine kinase activity
SAHN016_RS05040	COG4974	Belongs to the 'phage' integrase family
SAHN016_RS05045	COG4166	transmembrane transport
SAHN016_RS05060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAHN016_RS05065	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SAHN016_RS05070	COG5002	protein histidine kinase activity
SAHN016_RS05075	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS05085	COG0704	Plays a role in the regulation of phosphate uptake
SAHN016_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAHN016_RS05095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAHN016_RS05100	COG0581	inorganic phosphate transmembrane transporter activity
SAHN016_RS05105	COG0573	inorganic phosphate transmembrane transporter activity
SAHN016_RS05115	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SAHN016_RS05115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAHN016_RS05120	COG0483	inositol monophosphate 1-phosphatase activity
SAHN016_RS05135	COG0196	riboflavin kinase activity
SAHN016_RS05140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAHN016_RS05170	COG1136	(ABC) transporter
SAHN016_RS05175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAHN016_RS05180	COG0758	DNA mediated transformation
SAHN016_RS05185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAHN016_RS05190	COG4604	ABC transporter, ATP-binding protein
SAHN016_RS05195	COG4605	iron ion homeostasis
SAHN016_RS05200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAHN016_RS05205	COG0110	maltose O-acetyltransferase activity
SAHN016_RS05215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAHN016_RS05220	COG1376	ErfK ybiS ycfS ynhG family protein
SAHN016_RS05225	COG1966	Carbon starvation protein
SAHN016_RS05230	COG3279	Response regulator of the LytR AlgR family
SAHN016_RS05235	COG3275	phosphorelay sensor kinase activity
SAHN016_RS05340	COG0505	Belongs to the CarA family
SAHN016_RS05350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAHN016_RS05370	COG0488	(ABC) transporter
SAHN016_RS05380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAHN016_RS05390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SAHN016_RS05430	COG0095	Lipoate-protein ligase
SAHN016_RS05440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAHN016_RS05445	COG4684	Psort location CytoplasmicMembrane, score
SAHN016_RS05450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAHN016_RS05460	COG1132	(ABC) transporter
SAHN016_RS05490	COG2890	protein-(glutamine-N5) methyltransferase activity
SAHN016_RS05505	COG1942	4-Oxalocrotonate Tautomerase
SAHN016_RS05520	COG3976	FMN-binding domain protein
SAHN016_RS05520	COG1053	succinate dehydrogenase
SAHN016_RS05520	COG0431	NADPH-dependent FMN reductase
SAHN016_RS05530	COG2233	PERMEase
SAHN016_RS05545	COG0477	Major facilitator Superfamily
SAHN016_RS05560	COG4221	oxidoreductase activity
SAHN016_RS05565	COG0280	phosphate acetyltransferase
SAHN016_RS05570	COG0564	pseudouridine synthase activity
SAHN016_RS05575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SAHN016_RS05580	COG2357	RelA SpoT domain protein
SAHN016_RS05595	COG1104	cysteine desulfurase activity
SAHN016_RS05615	COG0628	permease
SAHN016_RS05620	COG2723	6-phospho-beta-galactosidase activity
SAHN016_RS05630	COG0561	phosphatase activity
SAHN016_RS05640	COG0038	chloride channel
SAHN016_RS05650	COG1177	transmembrane transport
SAHN016_RS05655	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAHN016_RS05665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAHN016_RS05670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAHN016_RS05690	COG0285	dihydrofolate synthase activity
SAHN016_RS05695	COG2962	Rard protein
SAHN016_RS05710	COG0726	polysaccharide deacetylase
SAHN016_RS05715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAHN016_RS05730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAHN016_RS05735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAHN016_RS05740	COG1012	belongs to the aldehyde dehydrogenase family
SAHN016_RS05820	COG2261	transglycosylase associated protein
SAHN016_RS05845	COG1115	amino acid carrier protein
SAHN016_RS05850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAHN016_RS05860	COG1346	cytolysis
SAHN016_RS05875	COG0539	negative regulation of cytoplasmic translation
SAHN016_RS05895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAHN016_RS05905	COG0187	DNA topoisomerase II activity
SAHN016_RS05910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SAHN016_RS05915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAHN016_RS05925	COG1083	cytidylyl-transferase
SAHN016_RS05925	COG2755	lipolytic protein G-D-S-L family
SAHN016_RS05940	COG2089	acid synthase
SAHN016_RS05955	COG1216	Glycosyl transferase, family 2
SAHN016_RS05955	COG1442	glycosyl transferase family 8
SAHN016_RS05960	COG1216	Glycosyl transferase, family 2
SAHN016_RS05960	COG1442	glycosyl transferase family 8
SAHN016_RS05975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAHN016_RS06000	COG1316	TRANSCRIPTIONal
SAHN016_RS06025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAHN016_RS06060	COG3842	ATPase activity
SAHN016_RS06075	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAHN016_RS06080	COG3527	Alpha-acetolactate decarboxylase
SAHN016_RS06085	COG0028	Belongs to the TPP enzyme family
SAHN016_RS06090	COG0457	Tetratricopeptide repeat
SAHN016_RS06095	COG0628	permease
SAHN016_RS06105	COG1051	belongs to the nudix hydrolase family
SAHN016_RS06110	COG5492	domain, Protein
SAHN016_RS06115	COG1088	dTDP-glucose 4,6-dehydratase activity
SAHN016_RS06125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SAHN016_RS06130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAHN016_RS06140	COG2384	SAM-dependent methyltransferase
SAHN016_RS06160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAHN016_RS06160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAHN016_RS06165	COG0300	oxidoreductase activity
SAHN016_RS06180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAHN016_RS06200	COG1523	belongs to the glycosyl hydrolase 13 family
SAHN016_RS06210	COG1573	uracil-dna glycosylase
SAHN016_RS06215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAHN016_RS06225	COG0584	glycerophosphoryl diester phosphodiesterase
SAHN016_RS06240	COG0534	Mate efflux family protein
SAHN016_RS06270	COG2176	DNA-directed DNA polymerase activity
SAHN016_RS06280	COG4974	Belongs to the 'phage' integrase family
SAHN016_RS06310	COG1674	ftsk spoiiie
SAHN016_RS06350	COG2040	homocysteine
SAHN016_RS06355	COG0833	amino acid
SAHN016_RS06390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAHN016_RS06400	COG3425	synthase
SAHN016_RS06415	COG1272	protein, Hemolysin III
SAHN016_RS06460	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS06465	COG2357	RelA SpoT domain protein
SAHN016_RS06470	COG1132	(ABC) transporter
SAHN016_RS06485	COG0737	Belongs to the 5'-nucleotidase family
SAHN016_RS06490	COG0242	peptide deformylase activity
SAHN016_RS06495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAHN016_RS06505	COG1132	(ABC) transporter
SAHN016_RS06520	COG0488	(ABC) transporter
SAHN016_RS06550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAHN016_RS06550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAHN016_RS06550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAHN016_RS06555	COG1105	Belongs to the carbohydrate kinase PfkB family
SAHN016_RS06560	COG1349	DNA-binding transcription factor activity
SAHN016_RS06565	COG1388	LysM domain
SAHN016_RS06565	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAHN016_RS06615	COG1837	Belongs to the UPF0109 family
SAHN016_RS06620	COG0228	four-way junction DNA binding
SAHN016_RS06625	COG0577	efflux transmembrane transporter activity
SAHN016_RS06630	COG1136	(ABC) transporter
SAHN016_RS06635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SAHN016_RS06645	COG0505	Belongs to the CarA family
SAHN016_RS06655	COG0564	pseudouridine synthase activity
SAHN016_RS06665	COG0583	DNA-binding transcription factor activity
SAHN016_RS06670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SAHN016_RS06695	COG1104	cysteine desulfurase activity
SAHN016_RS06705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAHN016_RS06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAHN016_RS06735	COG1368	sulfuric ester hydrolase activity
SAHN016_RS06740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAHN016_RS06750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAHN016_RS06780	COG2244	polysaccharide biosynthetic process
SAHN016_RS06790	COG1120	ATPase activity
SAHN016_RS06795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAHN016_RS06800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAHN016_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAHN016_RS06820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAHN016_RS06825	COG1253	flavin adenine dinucleotide binding
SAHN016_RS06830	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAHN016_RS06835	COG1242	4 iron, 4 sulfur cluster binding
SAHN016_RS06840	COG0671	phosphoesterase, PA-phosphatase related
SAHN016_RS06845	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAHN016_RS06875	COG0681	Belongs to the peptidase S26 family
SAHN016_RS06885	COG0297	glycogen (starch) synthase activity
SAHN016_RS06925	COG3475	LICD family
SAHN016_RS06940	COG0463	Glycosyl transferase, family 2
SAHN016_RS06945	COG1215	transferase activity, transferring glycosyl groups
SAHN016_RS06955	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAHN016_RS06960	COG2151	metal-sulfur cluster biosynthetic enzyme
SAHN016_RS06965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAHN016_RS06970	COG0358	DNA primase activity
SAHN016_RS06975	COG1970	mechanosensitive ion channel activity
SAHN016_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAHN016_RS06995	COG0004	ammonium transporteR
SAHN016_RS07005	COG1054	Belongs to the UPF0176 family
SAHN016_RS07015	COG2271	Major facilitator Superfamily
SAHN016_RS07020	COG0058	SHG alpha-glucan phosphorylase activity
SAHN016_RS07025	COG1640	4-alpha-glucanotransferase
SAHN016_RS07030	COG1609	Transcriptional regulator
SAHN016_RS07040	COG1175	transmembrane transport
SAHN016_RS07045	COG3833	ABC-type maltose transport systems, permease component
SAHN016_RS07050	COG3104	oligopeptide transport
SAHN016_RS07070	COG0438	transferase activity, transferring glycosyl groups
SAHN016_RS07100	COG1442	glycosyl transferase family 8
SAHN016_RS07105	COG1216	Glycosyl transferase, family 2
SAHN016_RS07105	COG1442	glycosyl transferase family 8
SAHN016_RS07110	COG1442	glycosyl transferase family 8
SAHN016_RS07115	COG1216	Glycosyl transferase, family 2
SAHN016_RS07115	COG1442	glycosyl transferase family 8
SAHN016_RS07120	COG1442	glycosyl transferase family 8
SAHN016_RS07150	COG0765	amino acid transport
SAHN016_RS07155	COG1126	abc transporter atp-binding protein
SAHN016_RS07180	COG2309	aminopeptidase activity
SAHN016_RS07190	COG0154	amidase activity
SAHN016_RS07195	COG1187	pseudouridine synthase activity
SAHN016_RS07200	COG0656	L-ascorbic acid biosynthetic process
SAHN016_RS07205	COG0778	Nitroreductase
SAHN016_RS07210	COG0346	lactoylglutathione lyase activity
SAHN016_RS07215	COG0463	Glycosyl transferase, family 2
SAHN016_RS07220	COG1113	amino acid transport
SAHN016_RS07225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAHN016_RS07230	COG0557	exoribonuclease II activity
SAHN016_RS07240	COG2814	Major facilitator Superfamily
SAHN016_RS07250	COG1131	(ABC) transporter
SAHN016_RS07260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAHN016_RS07265	COG1396	sequence-specific DNA binding
SAHN016_RS07300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SAHN016_RS07305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAHN016_RS07325	COG1702	phosphate starvation-inducible protein PhoH
SAHN016_RS07350	COG0233	cytoplasmic translational termination
SAHN016_RS07365	COG0444	Belongs to the ABC transporter superfamily
SAHN016_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAHN016_RS07375	COG0601	transmembrane transport
SAHN016_RS07380	COG0747	negative chemotaxis
SAHN016_RS07385	COG0081	regulation of translation
SAHN016_RS07405	COG1473	amidohydrolase
SAHN016_RS07410	COG0583	DNA-binding transcription factor activity
SAHN016_RS07425	COG2801	Transposase and inactivated derivatives
SAHN016_RS07430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAHN016_RS07435	COG1674	ftsk spoiiie
SAHN016_RS07440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAHN016_RS07465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAHN016_RS07495	COG0673	inositol 2-dehydrogenase activity
SAHN016_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
SAHN016_RS07570	COG3344	reverse transcriptase
SAHN016_RS07575	COG1114	Component of the transport system for branched-chain amino acids
SAHN016_RS07580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAHN016_RS07580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAHN016_RS07595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAHN016_RS07605	COG0708	Exodeoxyribonuclease III
SAHN016_RS07610	COG1393	Belongs to the ArsC family
SAHN016_RS07615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAHN016_RS07620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAHN016_RS07650	COG0470	DNA polymerase III
SAHN016_RS07665	COG0517	IMP dehydrogenase activity
SAHN016_RS07685	COG0559	Belongs to the binding-protein-dependent transport system permease family
SAHN016_RS07705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAHN016_RS07710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAHN016_RS07720	COG0531	amino acid
SAHN016_RS07725	COG0569	domain protein
SAHN016_RS07730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAHN016_RS07740	COG1187	pseudouridine synthase activity
SAHN016_RS07790	COG1827	regulation of RNA biosynthetic process
SAHN016_RS07805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAHN016_RS07810	COG1254	Belongs to the acylphosphatase family
SAHN016_RS07820	COG0765	amino acid transport
SAHN016_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAHN016_RS07840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SAHN016_RS07860	COG3344	reverse transcriptase
SAHN016_RS07875	COG1484	DNA-dependent DNA replication
SAHN016_RS07890	COG5002	protein histidine kinase activity
SAHN016_RS07895	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS07910	COG1704	LemA family
SAHN016_RS07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAHN016_RS07925	COG0569	domain protein
SAHN016_RS07950	COG1114	Component of the transport system for branched-chain amino acids
SAHN016_RS07955	COG1063	alcohol dehydrogenase
SAHN016_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAHN016_RS07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAHN016_RS07990	COG0217	transcriptional regulatory protein
SAHN016_RS07995	COG2376	Dihydroxyacetone kinase
SAHN016_RS08000	COG1309	transcriptional regulator
SAHN016_RS08005	COG2376	Dihydroxyacetone kinase
SAHN016_RS08010	COG1461	Dihydroxyacetone kinase
SAHN016_RS08015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAHN016_RS08020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAHN016_RS08030	COG0789	Transcriptional regulator
SAHN016_RS08045	COG2226	methyltransferase
SAHN016_RS08050	COG0799	negative regulation of ribosome biogenesis
SAHN016_RS08060	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAHN016_RS08065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAHN016_RS08070	COG1534	Rna-binding protein
SAHN016_RS08075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAHN016_RS08080	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAHN016_RS08105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAHN016_RS08105	COG0574	Belongs to the PEP-utilizing enzyme family
SAHN016_RS08115	COG0517	IMP dehydrogenase activity
SAHN016_RS08125	COG1335	isochorismatase
SAHN016_RS08130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SAHN016_RS08135	COG0436	Aminotransferase
SAHN016_RS08140	COG0589	response to stress
SAHN016_RS08145	COG0561	phosphatase activity
SAHN016_RS08150	COG0252	asparaginase activity
SAHN016_RS08160	COG4989	oxidoreductase activity
SAHN016_RS08165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAHN016_RS08170	COG3942	CHAP domain
SAHN016_RS08170	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAHN016_RS08180	COG0736	holo-[acyl-carrier-protein] synthase activity
SAHN016_RS08185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SAHN016_RS08195	COG1482	cell wall glycoprotein biosynthetic process
SAHN016_RS08200	COG1940	carbohydrate kinase activity
SAHN016_RS08205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS08205	COG1263	PTS System
SAHN016_RS08205	COG2190	(PTS) system
SAHN016_RS08210	COG1621	beta-fructofuranosidase activity
SAHN016_RS08215	COG1609	Transcriptional regulator
SAHN016_RS08220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAHN016_RS08230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAHN016_RS08250	COG2131	deaminase
SAHN016_RS08265	COG2814	Major facilitator Superfamily
SAHN016_RS08290	COG0629	single-stranded DNA binding
SAHN016_RS08295	COG0360	Binds together with S18 to 16S ribosomal RNA
SAHN016_RS08300	COG1194	a g-specific adenine glycosylase
SAHN016_RS08310	COG3118	belongs to the thioredoxin family
SAHN016_RS08340	COG0681	Belongs to the peptidase S26 family
SAHN016_RS08345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAHN016_RS08365	COG1882	Formate acetyltransferase
SAHN016_RS08370	COG3576	pyridoxamine 5-phosphate
SAHN016_RS08375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAHN016_RS08390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAHN016_RS08400	COG2814	Major facilitator Superfamily
SAHN016_RS08405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAHN016_RS08420	COG0142	geranyltranstransferase activity
SAHN016_RS08425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAHN016_RS08430	COG4988	ABC transporter
SAHN016_RS08435	COG1294	oxidase, subunit
SAHN016_RS08440	COG1271	oxidase subunit
SAHN016_RS08445	COG1252	NADH dehydrogenase
SAHN016_RS08480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAHN016_RS08485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAHN016_RS08485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SAHN016_RS08485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAHN016_RS08490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAHN016_RS08495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAHN016_RS08500	COG3711	transcriptional antiterminator
SAHN016_RS08500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAHN016_RS08520	COG4221	oxidoreductase activity
SAHN016_RS08530	COG0656	L-ascorbic acid biosynthetic process
SAHN016_RS08535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SAHN016_RS08550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAHN016_RS08555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAHN016_RS08560	COG0789	Transcriptional regulator
SAHN016_RS08575	COG2081	HI0933 family
SAHN016_RS08600	COG0456	acetyltransferase
SAHN016_RS08605	COG1214	PFAM Peptidase M22, glycoprotease
SAHN016_RS08620	COG3942	CHAP domain
SAHN016_RS08625	COG0174	glutamine synthetase
SAHN016_RS08630	COG0789	Transcriptional regulator
SAHN016_RS08645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAHN016_RS08670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAHN016_RS08695	COG1162	GTPase activity
SAHN016_RS08720	COG0084	hydrolase, TatD family'
SAHN016_RS08745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAHN016_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAHN016_RS08755	COG1696	Membrane protein involved in D-alanine export
SAHN016_RS08775	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS08785	COG3314	Sporulation integral membrane protein YlbJ
SAHN016_RS08795	COG3448	diguanylate cyclase activity
SAHN016_RS08795	COG4175	Glycine betaine
SAHN016_RS08800	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SAHN016_RS08820	COG1070	Carbohydrate kinase
SAHN016_RS08830	COG3775	system Galactitol-specific IIC component
SAHN016_RS08835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAHN016_RS08845	COG1609	Transcriptional regulator
SAHN016_RS08930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAHN016_RS08935	COG1428	Deoxynucleoside kinase
SAHN016_RS08945	COG0542	response to heat
SAHN016_RS08950	COG4463	regulation of RNA biosynthetic process
SAHN016_RS08960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAHN016_RS08970	COG0450	alkyl hydroperoxide reductase
SAHN016_RS08985	COG0025	NhaP-type Na H and K H
SAHN016_RS08995	COG1619	proteins homologs of microcin C7 resistance protein MccF
SAHN016_RS09000	COG3590	peptidase
SAHN016_RS09025	COG1609	Transcriptional regulator
SAHN016_RS09050	COG2176	DNA-directed DNA polymerase activity
SAHN016_RS09055	COG1388	LysM domain
SAHN016_RS09055	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAHN016_RS09070	COG4589	Belongs to the CDS family
SAHN016_RS09075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAHN016_RS09080	COG1862	Preprotein translocase
SAHN016_RS09100	COG3493	citrate carrier protein
SAHN016_RS09105	COG3290	protein histidine kinase activity
SAHN016_RS09110	COG4565	transcriptional regulatory protein
SAHN016_RS09115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAHN016_RS09125	COG3842	ATPase activity
SAHN016_RS09210	COG0737	Belongs to the 5'-nucleotidase family
SAHN016_RS09220	COG1363	Peptidase, m42
SAHN016_RS09240	COG2207	Transcriptional regulator
SAHN016_RS09240	COG4753	response regulator
SAHN016_RS09245	COG2972	Histidine kinase
SAHN016_RS09250	COG3716	PTS system mannose fructose sorbose family IID component
SAHN016_RS09255	COG3715	PTS system
SAHN016_RS09285	COG1131	(ABC) transporter
SAHN016_RS09295	COG2274	protein secretion by the type I secretion system
SAHN016_RS09300	COG3290	protein histidine kinase activity
SAHN016_RS09315	COG1263	PTS System
SAHN016_RS09315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAHN016_RS09315	COG2190	(PTS) system
SAHN016_RS09320	COG5002	protein histidine kinase activity
SAHN016_RS09325	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS09340	COG0581	inorganic phosphate transmembrane transporter activity
SAHN016_RS09345	COG0573	inorganic phosphate transmembrane transporter activity
SAHN016_RS09360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAHN016_RS09375	COG0789	Transcriptional regulator
SAHN016_RS09385	COG0494	nUDIX hydrolase
SAHN016_RS09400	COG0456	acetyltransferase
SAHN016_RS09405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAHN016_RS09430	COG0582	viral genome integration into host DNA
SAHN016_RS09440	COG2946	Replication initiation factor
SAHN016_RS09460	COG2378	regulation of single-species biofilm formation
SAHN016_RS09465	COG0693	protein deglycase activity
SAHN016_RS09550	COG1131	(ABC) transporter
SAHN016_RS09595	COG1131	(ABC) transporter
SAHN016_RS09605	COG1396	sequence-specific DNA binding
SAHN016_RS09615	COG1694	Mazg nucleotide pyrophosphohydrolase
SAHN016_RS09620	COG1611	Belongs to the LOG family
SAHN016_RS09630	COG2897	thiosulfate sulfurtransferase activity
SAHN016_RS09645	COG0371	Dehydrogenase
SAHN016_RS09655	COG0646	methionine synthase
SAHN016_RS09655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAHN016_RS09670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SAHN016_RS09685	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS09690	COG2205	protein histidine kinase activity
SAHN016_RS09690	COG2770	Histidine kinase
SAHN016_RS09705	COG2814	Major facilitator Superfamily
SAHN016_RS09710	COG4667	esterase of the alpha-beta hydrolase superfamily
SAHN016_RS09730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAHN016_RS09735	COG0564	pseudouridine synthase activity
SAHN016_RS09755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAHN016_RS09760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SAHN016_RS09780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAHN016_RS09785	COG1116	anion transmembrane transporter activity
SAHN016_RS09785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SAHN016_RS09790	COG4120	Belongs to the binding-protein-dependent transport system permease family
SAHN016_RS09800	COG0561	phosphatase activity
SAHN016_RS09805	COG2514	catechol 2,3-dioxygenase activity
SAHN016_RS09815	COG0602	queuosine metabolic process
SAHN016_RS09835	COG1328	CTP reductase activity
SAHN016_RS09855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAHN016_RS09865	COG1393	Belongs to the ArsC family
SAHN016_RS09870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SAHN016_RS09880	COG2818	Glycosylase
SAHN016_RS09925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAHN016_RS09930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAHN016_RS09950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAHN016_RS09955	COG3344	reverse transcriptase
SAHN016_RS10010	COG0582	viral genome integration into host DNA
SAHN016_RS10020	COG0745	RESPONSE REGULATOR receiver
SAHN016_RS10025	COG5002	protein histidine kinase activity
SAHN016_RS10030	COG1288	antiporter activity
SAHN016_RS10040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAHN016_RS10045	COG3852	Histidine kinase
SAHN016_RS10050	COG0784	Response regulator, receiver
SAHN016_RS10055	COG0517	IMP dehydrogenase activity
SAHN016_RS10055	COG1125	glycine betaine transport
SAHN016_RS10060	COG1174	glycine betaine transport
SAHN016_RS10065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAHN016_RS10065	COG0392	lysyltransferase activity
SAHN016_RS10075	COG3759	membrane
SAHN016_RS10105	COG0305	Participates in initiation and elongation during chromosome replication
SAHN016_RS10125	COG2095	MarC family integral membrane protein
SAHN016_RS10135	COG1760	l-serine dehydratase
SAHN016_RS10140	COG1760	l-serine dehydratase
SAHN016_RS10145	COG0741	lytic transglycosylase activity
SAHN016_RS10170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAHN016_RS10175	COG0612	Peptidase, M16
SAHN016_RS10180	COG0612	Peptidase, M16
SAHN016_RS10185	COG2501	S4 domain
SAHN016_RS10205	COG0516	GMP reductase activity
SAHN016_RS10205	COG0517	IMP dehydrogenase activity
SAHN016_RS10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAHN016_RS10230	COG0454	-acetyltransferase
SAHN016_RS10245	COG0549	Belongs to the carbamate kinase family
SAHN016_RS10260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAHN016_RS10265	COG0488	(ABC) transporter
SAHN016_RS10270	COG4485	Bacterial membrane protein, YfhO
SAHN016_RS10290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SAHN016_RS10295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAHN016_RS10300	COG1475	DNA binding