locus-tag	class	description
LLZ83_RS00010	COG0592	DNA-directed DNA polymerase activity
LLZ83_RS00030	COG0012	GTP binding
LLZ83_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLZ83_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLZ83_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLZ83_RS00260	COG0436	Aminotransferase
LLZ83_RS00275	COG0416	fatty acid biosynthetic process
LLZ83_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLZ83_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLZ83_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLZ83_RS00315	COG0138	bifunctional purine biosynthesis protein purh
LLZ83_RS00340	COG1175	transmembrane transport
LLZ83_RS00345	COG0395	ABC-type sugar transport system, permease component
LLZ83_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLZ83_RS00370	COG3458	cephalosporin-C deacetylase activity
LLZ83_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLZ83_RS00405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLZ83_RS00420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLZ83_RS00430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LLZ83_RS00430	COG2755	lipolytic protein G-D-S-L family
LLZ83_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
LLZ83_RS00435	COG1454	alcohol dehydrogenase
LLZ83_RS00440	COG1064	alcohol dehydrogenase
LLZ83_RS00450	COG0534	Mate efflux family protein
LLZ83_RS00560	COG0201	protein transport
LLZ83_RS00565	COG0563	adenylate kinase activity
LLZ83_RS00580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLZ83_RS00590	COG0202	RNA polymerase activity
LLZ83_RS00715	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLZ83_RS00720	COG1420	regulation of RNA biosynthetic process
LLZ83_RS00730	COG0443	Heat shock 70 kDa protein
LLZ83_RS00735	COG0484	heat shock protein binding
LLZ83_RS00740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLZ83_RS00745	COG0101	tRNA pseudouridine synthase activity
LLZ83_RS00750	COG0351	phosphomethylpyrimidine kinase
LLZ83_RS00755	COG4720	Psort location CytoplasmicMembrane, score
LLZ83_RS00765	COG0668	transmembrane transport
LLZ83_RS00770	COG0544	peptidyl-prolyl cis-trans isomerase activity
LLZ83_RS00795	COG0756	dUTP diphosphatase activity
LLZ83_RS00810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLZ83_RS00815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLZ83_RS00820	COG1879	ABC-type sugar transport system periplasmic component
LLZ83_RS00825	COG1172	Belongs to the binding-protein-dependent transport system permease family
LLZ83_RS00830	COG1129	ABC transporter
LLZ83_RS00835	COG1869	D-ribose catabolic process
LLZ83_RS00840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLZ83_RS00845	COG1609	Transcriptional regulator
LLZ83_RS00850	COG0577	efflux transmembrane transporter activity
LLZ83_RS00855	COG1136	(ABC) transporter
LLZ83_RS00860	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS00865	COG2205	protein histidine kinase activity
LLZ83_RS00870	COG0137	argininosuccinate synthase activity
LLZ83_RS00875	COG0165	Argininosuccinate lyase
LLZ83_RS00880	COG0191	fructose-bisphosphate aldolase activity
LLZ83_RS00900	COG1461	Dihydroxyacetone kinase
LLZ83_RS00915	COG1126	abc transporter atp-binding protein
LLZ83_RS00920	COG0765	amino acid transport
LLZ83_RS00940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLZ83_RS00950	COG0719	Fe-S assembly protein
LLZ83_RS00955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLZ83_RS00965	COG0719	Fe-S assembly protein
LLZ83_RS00970	COG1686	Belongs to the peptidase S11 family
LLZ83_RS00975	COG1686	Belongs to the peptidase S11 family
LLZ83_RS00980	COG4166	transmembrane transport
LLZ83_RS00985	COG0601	transmembrane transport
LLZ83_RS00990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLZ83_RS00995	COG0444	Belongs to the ABC transporter superfamily
LLZ83_RS01000	COG4608	Belongs to the ABC transporter superfamily
LLZ83_RS01030	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LLZ83_RS01040	COG1121	(ABC) transporter
LLZ83_RS01045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLZ83_RS01055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LLZ83_RS01060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLZ83_RS01060	COG4499	WXG100 protein secretion system (Wss), protein YukC
LLZ83_RS01080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLZ83_RS01085	COG1459	type II secretion system
LLZ83_RS01115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLZ83_RS01140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLZ83_RS01145	COG1363	Peptidase, m42
LLZ83_RS01160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLZ83_RS01165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLZ83_RS01175	COG0629	single-stranded DNA binding
LLZ83_RS01180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLZ83_RS01200	COG1346	cytolysis
LLZ83_RS01210	COG0601	transmembrane transport
LLZ83_RS01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLZ83_RS01220	COG1122	ATPase activity
LLZ83_RS01230	COG1263	PTS System
LLZ83_RS01230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS01235	COG0366	Alpha amylase catalytic
LLZ83_RS01240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLZ83_RS01255	COG3959	Transketolase, thiamine diphosphate binding domain
LLZ83_RS01260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLZ83_RS01265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LLZ83_RS01275	COG1185	polyribonucleotide nucleotidyltransferase activity
LLZ83_RS01285	COG1045	serine acetyltransferase
LLZ83_RS01295	COG0215	cysteine-tRNA ligase activity
LLZ83_RS01300	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LLZ83_RS01330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLZ83_RS01340	COG0582	viral genome integration into host DNA
LLZ83_RS01390	COG4974	Belongs to the 'phage' integrase family
LLZ83_RS01400	COG0732	type I restriction modification DNA specificity domain
LLZ83_RS01420	COG1396	sequence-specific DNA binding
LLZ83_RS01435	COG1732	Glycine betaine
LLZ83_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
LLZ83_RS01580	COG1695	Transcriptional regulator
LLZ83_RS01595	COG1755	Isoprenylcysteine carboxyl methyltransferase
LLZ83_RS01610	COG0751	glycine-tRNA ligase activity
LLZ83_RS01635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLZ83_RS01640	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLZ83_RS01660	COG1131	(ABC) transporter
LLZ83_RS01670	COG2190	(PTS) system
LLZ83_RS01670	COG1263	PTS System
LLZ83_RS01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS01675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LLZ83_RS01680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLZ83_RS01685	COG0275	rRNA processing
LLZ83_RS01695	COG0768	penicillin binding
LLZ83_RS01705	COG0513	Belongs to the DEAD box helicase family
LLZ83_RS01720	COG1126	abc transporter atp-binding protein
LLZ83_RS01730	COG0492	ferredoxin-NADP+ reductase activity
LLZ83_RS01735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLZ83_RS01745	COG3579	cysteine-type endopeptidase activity
LLZ83_RS01750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLZ83_RS01775	COG0116	Belongs to the methyltransferase superfamily
LLZ83_RS01785	COG1854	S-ribosylhomocysteine lyase activity
LLZ83_RS01790	COG1418	mRNA catabolic process
LLZ83_RS01790	COG4372	Transposase
LLZ83_RS01805	COG2197	response regulator
LLZ83_RS01815	COG0194	GDP metabolic process
LLZ83_RS01825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLZ83_RS01830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LLZ83_RS01835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLZ83_RS01835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLZ83_RS01845	COG0515	serine threonine protein kinase
LLZ83_RS01845	COG2815	serine threonine protein kinase
LLZ83_RS01855	COG4585	Histidine kinase
LLZ83_RS01860	COG2197	response regulator
LLZ83_RS01870	COG1098	S1 RNA binding domain
LLZ83_RS01875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLZ83_RS01880	COG1349	DNA-binding transcription factor activity
LLZ83_RS01890	COG1447	Phosphotransferase system cellobiose-specific component IIA
LLZ83_RS01900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLZ83_RS01905	COG1882	Formate acetyltransferase
LLZ83_RS01925	COG1739	Uncharacterized protein family UPF0029
LLZ83_RS01930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LLZ83_RS01935	COG1040	competence protein
LLZ83_RS01970	COG0527	aspartate kinase activity
LLZ83_RS01975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LLZ83_RS01980	COG1024	Enoyl-CoA hydratase
LLZ83_RS01990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LLZ83_RS02000	COG2070	2-Nitropropane dioxygenase
LLZ83_RS02005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLZ83_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
LLZ83_RS02015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLZ83_RS02030	COG0439	Biotin carboxylase
LLZ83_RS02050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLZ83_RS02065	COG3716	PTS system mannose fructose sorbose family IID component
LLZ83_RS02070	COG3715	PTS system
LLZ83_RS02080	COG0561	phosphatase activity
LLZ83_RS02095	COG2252	PERMEase
LLZ83_RS02100	COG0802	atpase or kinase
LLZ83_RS02110	COG1316	TRANSCRIPTIONal
LLZ83_RS02120	COG0537	adenosine 5'-monophosphoramidase activity
LLZ83_RS02135	COG1131	(ABC) transporter
LLZ83_RS02140	COG4473	ABC transporter
LLZ83_RS02150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LLZ83_RS02165	COG0195	Participates in both transcription termination and antitermination
LLZ83_RS02170	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LLZ83_RS02180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LLZ83_RS02185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLZ83_RS02210	COG2860	membrane
LLZ83_RS02220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLZ83_RS02220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLZ83_RS02225	COG1832	CoA-binding protein
LLZ83_RS02245	COG5002	protein histidine kinase activity
LLZ83_RS02265	COG1268	BioY protein
LLZ83_RS02270	COG1234	tRNA 3'-trailer cleavage
LLZ83_RS02285	COG0166	Belongs to the GPI family
LLZ83_RS02290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLZ83_RS02295	COG0705	Rhomboid family
LLZ83_RS02295	COG0457	Tetratricopeptide repeat
LLZ83_RS02300	COG1744	ABC transporter substrate-binding protein PnrA-like
LLZ83_RS02305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LLZ83_RS02320	COG0706	membrane insertase activity
LLZ83_RS02390	COG2137	regulation of response to DNA damage stimulus
LLZ83_RS02395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLZ83_RS02415	COG1216	Glycosyl transferase, family 2
LLZ83_RS02415	COG1442	glycosyl transferase family 8
LLZ83_RS02455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLZ83_RS02465	COG0789	Transcriptional regulator
LLZ83_RS02530	COG2226	methyltransferase
LLZ83_RS02540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLZ83_RS02545	COG3414	Phosphotransferase system galactitol-specific IIB component
LLZ83_RS02550	COG3775	system Galactitol-specific IIC component
LLZ83_RS02555	COG0235	Class ii aldolase
LLZ83_RS02565	COG3775	system Galactitol-specific IIC component
LLZ83_RS02570	COG3414	Phosphotransferase system galactitol-specific IIB component
LLZ83_RS02575	COG2207	Transcriptional regulator
LLZ83_RS02585	COG1175	transmembrane transport
LLZ83_RS02590	COG0395	ABC-type sugar transport system, permease component
LLZ83_RS02600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLZ83_RS02610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLZ83_RS02615	COG2017	converts alpha-aldose to the beta-anomer
LLZ83_RS02675	COG1518	maintenance of DNA repeat elements
LLZ83_RS02680	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLZ83_RS02695	COG2315	Protein conserved in bacteria
LLZ83_RS02710	COG0742	ribosomal rna small subunit methyltransferase
LLZ83_RS02725	COG3480	Lon protease (S16) C-terminal proteolytic domain
LLZ83_RS02730	COG0737	Belongs to the 5'-nucleotidase family
LLZ83_RS02735	COG4470	Protein conserved in bacteria
LLZ83_RS02750	COG1132	(ABC) transporter
LLZ83_RS02755	COG1132	(ABC) transporter
LLZ83_RS02760	COG0512	Glutamine amidotransferase of anthranilate synthase
LLZ83_RS02765	COG1268	BioY protein
LLZ83_RS02770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LLZ83_RS02790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLZ83_RS02805	COG1940	carbohydrate kinase activity
LLZ83_RS02810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLZ83_RS02815	COG1217	gtp-binding protein TYPA
LLZ83_RS02825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLZ83_RS02850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLZ83_RS02860	COG0762	integral membrane protein
LLZ83_RS02870	COG3599	regulation of cell shape
LLZ83_RS02885	COG0494	nUDIX hydrolase
LLZ83_RS02890	COG0542	response to heat
LLZ83_RS02895	COG4703	Protein of unknown function (DUF1797)
LLZ83_RS02900	COG0765	amino acid transport
LLZ83_RS02905	COG1126	abc transporter atp-binding protein
LLZ83_RS02910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLZ83_RS02920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LLZ83_RS02925	COG1570	exodeoxyribonuclease VII activity
LLZ83_RS02930	COG1722	exodeoxyribonuclease VII activity
LLZ83_RS02940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LLZ83_RS02945	COG1438	arginine binding
LLZ83_RS02950	COG0497	DNA recombination
LLZ83_RS02955	COG1307	EDD domain protein, DegV family
LLZ83_RS02960	COG2755	lipolytic protein G-D-S-L family
LLZ83_RS03005	COG1078	dGTPase activity
LLZ83_RS03030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LLZ83_RS03040	COG2884	Cell division ATP-binding protein ftsE
LLZ83_RS03045	COG2177	Part of the ABC transporter FtsEX involved in
LLZ83_RS03065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLZ83_RS03065	COG1199	ATP-dependent helicase activity
LLZ83_RS03070	COG0436	Aminotransferase
LLZ83_RS03075	COG0017	Asparaginyl-tRNA synthetase
LLZ83_RS03095	COG1660	Displays ATPase and GTPase activities
LLZ83_RS03120	COG0254	rRNA binding
LLZ83_RS03125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLZ83_RS03130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLZ83_RS03135	COG0716	FMN binding
LLZ83_RS03140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LLZ83_RS03140	COG1605	Chorismate mutase
LLZ83_RS03145	COG0038	chloride channel
LLZ83_RS03150	COG0335	large ribosomal subunit rRNA binding
LLZ83_RS03160	COG0582	viral genome integration into host DNA
LLZ83_RS03565	COG1136	(ABC) transporter
LLZ83_RS03580	COG5002	protein histidine kinase activity
LLZ83_RS03600	COG0772	Belongs to the SEDS family
LLZ83_RS03620	COG0560	Phosphoserine phosphatase
LLZ83_RS03635	COG0148	phosphopyruvate hydratase activity
LLZ83_RS03655	COG1316	TRANSCRIPTIONal
LLZ83_RS03685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLZ83_RS03690	COG4555	ABC transporter
LLZ83_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
LLZ83_RS03720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLZ83_RS03725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLZ83_RS03745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LLZ83_RS03750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLZ83_RS03785	COG1136	(ABC) transporter
LLZ83_RS03800	COG0586	Pfam SNARE associated Golgi protein
LLZ83_RS03805	COG4619	ABC transporter
LLZ83_RS03810	COG0390	transport system, permease component
LLZ83_RS03820	COG0583	DNA-binding transcription factor activity
LLZ83_RS03830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLZ83_RS03845	COG3250	beta-galactosidase activity
LLZ83_RS03850	COG2186	Transcriptional regulator
LLZ83_RS03855	COG0800	Aldolase
LLZ83_RS03860	COG1904	glucuronate isomerase
LLZ83_RS03865	COG1312	Catalyzes the dehydration of D-mannonate
LLZ83_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
LLZ83_RS03890	COG1609	Transcriptional regulator
LLZ83_RS03905	COG0438	transferase activity, transferring glycosyl groups
LLZ83_RS03930	COG0765	amino acid transport
LLZ83_RS03935	COG0765	amino acid transport
LLZ83_RS03940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLZ83_RS03945	COG1126	abc transporter atp-binding protein
LLZ83_RS03950	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS03955	COG5002	protein histidine kinase activity
LLZ83_RS03960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLZ83_RS03965	COG2832	Protein of unknown function (DUF454)
LLZ83_RS03975	COG1196	nuclear chromosome segregation
LLZ83_RS03980	COG0561	phosphatase activity
LLZ83_RS03985	COG0561	phosphatase activity
LLZ83_RS03990	COG0552	protein localization to endoplasmic reticulum
LLZ83_RS03995	COG3689	TIGRFAM TIGR03943 family protein
LLZ83_RS04000	COG0701	Predicted permease
LLZ83_RS04015	COG2183	response to ionizing radiation
LLZ83_RS04020	COG3091	SprT-like family
LLZ83_RS04025	COG1983	PspC domain protein
LLZ83_RS04060	COG0826	peptidase U32
LLZ83_RS04065	COG4443	Transcriptional Coactivator p15 (PC4)
LLZ83_RS04075	COG1914	H( )-stimulated, divalent metal cation uptake system
LLZ83_RS04090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLZ83_RS04090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLZ83_RS04115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLZ83_RS04140	COG1164	Oligoendopeptidase f
LLZ83_RS04150	COG0772	Belongs to the SEDS family
LLZ83_RS04170	COG0768	penicillin binding
LLZ83_RS04185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLZ83_RS04190	COG2223	nitrite transmembrane transporter activity
LLZ83_RS04215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLZ83_RS04220	COG2011	ABC-type metal ion transport system permease component
LLZ83_RS04225	COG1464	Belongs to the NlpA lipoprotein family
LLZ83_RS04230	COG0513	Belongs to the DEAD box helicase family
LLZ83_RS04240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LLZ83_RS04245	COG0204	Acyl-transferase
LLZ83_RS04250	COG1555	photosystem II stabilization
LLZ83_RS04250	COG1596	polysaccharide export
LLZ83_RS04255	COG0658	competence protein
LLZ83_RS04255	COG2333	competence protein COMEC
LLZ83_RS04260	COG0561	phosphatase activity
LLZ83_RS04265	COG1609	Transcriptional regulator
LLZ83_RS04270	COG0657	acetylesterase activity
LLZ83_RS04275	COG2226	methyltransferase
LLZ83_RS04285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LLZ83_RS04290	COG3711	transcriptional antiterminator
LLZ83_RS04295	COG2190	(PTS) system
LLZ83_RS04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS04295	COG1263	PTS System
LLZ83_RS04305	COG3835	regulator
LLZ83_RS04310	COG1929	Belongs to the glycerate kinase type-1 family
LLZ83_RS04315	COG2610	gluconate transmembrane transporter activity
LLZ83_RS04325	COG1846	Transcriptional regulator
LLZ83_RS04330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLZ83_RS04340	COG0363	glucosamine-6-phosphate deaminase activity
LLZ83_RS04345	COG0435	Glutathione S-transferase
LLZ83_RS04350	COG1187	pseudouridine synthase activity
LLZ83_RS04365	COG1164	Oligoendopeptidase f
LLZ83_RS04370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LLZ83_RS04375	COG4122	O-methyltransferase activity
LLZ83_RS04380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLZ83_RS04385	COG4894	glucomannan catabolic process
LLZ83_RS04390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLZ83_RS04395	COG1811	Na channel or pump
LLZ83_RS04400	COG1442	glycosyl transferase family 8
LLZ83_RS04410	COG1476	TRANSCRIPTIONal
LLZ83_RS04425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLZ83_RS04430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLZ83_RS04435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LLZ83_RS04450	COG1012	belongs to the aldehyde dehydrogenase family
LLZ83_RS04455	COG0726	polysaccharide deacetylase
LLZ83_RS04460	COG0513	Belongs to the DEAD box helicase family
LLZ83_RS04470	COG1956	GAF domain-containing protein
LLZ83_RS04475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLZ83_RS04485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLZ83_RS04485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLZ83_RS04490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLZ83_RS04515	COG4721	ABC-type cobalt transport system, permease component
LLZ83_RS04520	COG1122	ATPase activity
LLZ83_RS04540	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LLZ83_RS04545	COG0352	thiamine-phosphate diphosphorylase activity
LLZ83_RS04550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLZ83_RS04560	COG4109	DRTGG domain
LLZ83_RS04565	COG0024	Methionine aminopeptidase
LLZ83_RS04575	COG2246	polysaccharide biosynthetic process
LLZ83_RS04580	COG4708	membrane
LLZ83_RS04585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLZ83_RS04590	COG1597	lipid kinase activity
LLZ83_RS04595	COG1523	belongs to the glycosyl hydrolase 13 family
LLZ83_RS04600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLZ83_RS04605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLZ83_RS04610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLZ83_RS04615	COG0297	glycogen (starch) synthase activity
LLZ83_RS04625	COG0356	it plays a direct role in the translocation of protons across the membrane
LLZ83_RS04645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LLZ83_RS04655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LLZ83_RS04665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLZ83_RS04680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LLZ83_RS04690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLZ83_RS04690	COG0072	phenylalanine-tRNA ligase activity
LLZ83_RS04695	COG2321	neutral zinc metallopeptidase
LLZ83_RS04700	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LLZ83_RS04705	COG1074	ATP-dependent DNA helicase activity
LLZ83_RS04715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLZ83_RS04720	COG0488	(ABC) transporter
LLZ83_RS04725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LLZ83_RS04730	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLZ83_RS04730	COG0022	dehydrogenase e1 component
LLZ83_RS04735	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLZ83_RS04745	COG0095	Lipoate-protein ligase
LLZ83_RS04750	COG3442	glutamine amidotransferase
LLZ83_RS04755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLZ83_RS04760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LLZ83_RS04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLZ83_RS04795	COG0647	UMP catabolic process
LLZ83_RS04805	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LLZ83_RS04810	COG1518	maintenance of DNA repeat elements
LLZ83_RS04815	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLZ83_RS04840	COG0481	GTPase activity
LLZ83_RS04850	COG1418	mRNA catabolic process
LLZ83_RS04855	COG0456	acetyltransferase
LLZ83_RS04865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLZ83_RS04895	COG1131	(ABC) transporter
LLZ83_RS04900	COG1725	Transcriptional regulator
LLZ83_RS04910	COG0205	6-phosphofructokinase activity
LLZ83_RS04915	COG0469	pyruvate kinase activity
LLZ83_RS04925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LLZ83_RS04930	COG2824	Alkylphosphonate utilization operon protein PhnA
LLZ83_RS04935	COG0765	amino acid transport
LLZ83_RS04940	COG1126	abc transporter atp-binding protein
LLZ83_RS04955	COG1072	(Pantothenic acid kinase))
LLZ83_RS04960	COG2813	Specifically methylates the guanine in position
LLZ83_RS04970	COG1744	ABC transporter substrate-binding protein PnrA-like
LLZ83_RS04975	COG3845	ABC transporter
LLZ83_RS04980	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLZ83_RS04985	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLZ83_RS05005	COG3764	Sortase (surface protein transpeptidase)
LLZ83_RS05010	COG0346	lactoylglutathione lyase activity
LLZ83_RS05040	COG1674	ftsk spoiiie
LLZ83_RS05045	COG2946	Replication initiation factor
LLZ83_RS05095	COG0741	lytic transglycosylase activity
LLZ83_RS05095	COG0791	NLP P60 protein
LLZ83_RS05140	COG0582	viral genome integration into host DNA
LLZ83_RS05150	COG2188	Transcriptional regulator
LLZ83_RS05155	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LLZ83_RS05165	COG1464	Belongs to the NlpA lipoprotein family
LLZ83_RS05180	COG1136	(ABC) transporter
LLZ83_RS05190	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS05195	COG5002	protein histidine kinase activity
LLZ83_RS05200	COG4974	Belongs to the 'phage' integrase family
LLZ83_RS05220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLZ83_RS05225	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLZ83_RS05230	COG5002	protein histidine kinase activity
LLZ83_RS05235	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS05245	COG0704	Plays a role in the regulation of phosphate uptake
LLZ83_RS05250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLZ83_RS05255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLZ83_RS05260	COG0581	inorganic phosphate transmembrane transporter activity
LLZ83_RS05265	COG0573	inorganic phosphate transmembrane transporter activity
LLZ83_RS05275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLZ83_RS05275	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LLZ83_RS05280	COG0483	inositol monophosphate 1-phosphatase activity
LLZ83_RS05285	COG4476	Belongs to the UPF0223 family
LLZ83_RS05295	COG0196	riboflavin kinase activity
LLZ83_RS05300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LLZ83_RS05330	COG1136	(ABC) transporter
LLZ83_RS05335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLZ83_RS05340	COG0758	DNA mediated transformation
LLZ83_RS05345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LLZ83_RS05350	COG4604	ABC transporter, ATP-binding protein
LLZ83_RS05355	COG4605	iron ion homeostasis
LLZ83_RS05360	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLZ83_RS05365	COG0110	maltose O-acetyltransferase activity
LLZ83_RS05375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLZ83_RS05380	COG1376	ErfK ybiS ycfS ynhG family protein
LLZ83_RS05385	COG1966	Carbon starvation protein
LLZ83_RS05390	COG3279	Response regulator of the LytR AlgR family
LLZ83_RS05395	COG3275	phosphorelay sensor kinase activity
LLZ83_RS05530	COG0505	Belongs to the CarA family
LLZ83_RS05545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LLZ83_RS05560	COG0488	(ABC) transporter
LLZ83_RS05570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLZ83_RS05580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLZ83_RS05630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLZ83_RS05635	COG4684	Psort location CytoplasmicMembrane, score
LLZ83_RS05640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLZ83_RS05650	COG1132	(ABC) transporter
LLZ83_RS05670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LLZ83_RS05680	COG2890	protein-(glutamine-N5) methyltransferase activity
LLZ83_RS05695	COG1942	4-Oxalocrotonate Tautomerase
LLZ83_RS05710	COG0431	NADPH-dependent FMN reductase
LLZ83_RS05710	COG1053	succinate dehydrogenase
LLZ83_RS05710	COG3976	FMN-binding domain protein
LLZ83_RS05720	COG2233	PERMEase
LLZ83_RS05735	COG0477	Major facilitator Superfamily
LLZ83_RS05750	COG4221	oxidoreductase activity
LLZ83_RS05755	COG0280	phosphate acetyltransferase
LLZ83_RS05760	COG0564	pseudouridine synthase activity
LLZ83_RS05770	COG2357	RelA SpoT domain protein
LLZ83_RS05785	COG1104	cysteine desulfurase activity
LLZ83_RS05805	COG0628	permease
LLZ83_RS05810	COG2723	6-phospho-beta-galactosidase activity
LLZ83_RS05820	COG0561	phosphatase activity
LLZ83_RS05830	COG0038	chloride channel
LLZ83_RS05840	COG1177	transmembrane transport
LLZ83_RS05845	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLZ83_RS05855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LLZ83_RS05860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLZ83_RS05880	COG0285	dihydrofolate synthase activity
LLZ83_RS05885	COG2962	Rard protein
LLZ83_RS05900	COG0726	polysaccharide deacetylase
LLZ83_RS05905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLZ83_RS05910	COG1012	belongs to the aldehyde dehydrogenase family
LLZ83_RS05985	COG2261	transglycosylase associated protein
LLZ83_RS06010	COG1115	amino acid carrier protein
LLZ83_RS06015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLZ83_RS06025	COG1346	cytolysis
LLZ83_RS06040	COG0539	negative regulation of cytoplasmic translation
LLZ83_RS06060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLZ83_RS06070	COG0187	DNA topoisomerase II activity
LLZ83_RS06075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLZ83_RS06080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLZ83_RS06105	COG2089	acid synthase
LLZ83_RS06120	COG1216	Glycosyl transferase, family 2
LLZ83_RS06120	COG1442	glycosyl transferase family 8
LLZ83_RS06130	COG1215	transferase activity, transferring glycosyl groups
LLZ83_RS06135	COG0463	Glycosyl transferase, family 2
LLZ83_RS06155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLZ83_RS06180	COG1316	TRANSCRIPTIONal
LLZ83_RS06205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LLZ83_RS06240	COG3842	ATPase activity
LLZ83_RS06255	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LLZ83_RS06260	COG3527	Alpha-acetolactate decarboxylase
LLZ83_RS06265	COG0028	Belongs to the TPP enzyme family
LLZ83_RS06270	COG0457	Tetratricopeptide repeat
LLZ83_RS06275	COG0628	permease
LLZ83_RS06285	COG1051	belongs to the nudix hydrolase family
LLZ83_RS06290	COG5492	domain, Protein
LLZ83_RS06295	COG1088	dTDP-glucose 4,6-dehydratase activity
LLZ83_RS06305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLZ83_RS06310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLZ83_RS06320	COG2384	SAM-dependent methyltransferase
LLZ83_RS06340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LLZ83_RS06340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLZ83_RS06345	COG0300	oxidoreductase activity
LLZ83_RS06360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLZ83_RS06390	COG1573	uracil-dna glycosylase
LLZ83_RS06395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLZ83_RS06420	COG0534	Mate efflux family protein
LLZ83_RS06460	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLZ83_RS06525	COG2040	homocysteine
LLZ83_RS06530	COG0833	amino acid
LLZ83_RS06560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLZ83_RS06570	COG3425	synthase
LLZ83_RS06585	COG1272	protein, Hemolysin III
LLZ83_RS06630	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS06635	COG2357	RelA SpoT domain protein
LLZ83_RS06655	COG0737	Belongs to the 5'-nucleotidase family
LLZ83_RS06660	COG0242	peptide deformylase activity
LLZ83_RS06665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LLZ83_RS06675	COG1132	(ABC) transporter
LLZ83_RS06690	COG0488	(ABC) transporter
LLZ83_RS06725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLZ83_RS06725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLZ83_RS06725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLZ83_RS06730	COG1105	Belongs to the carbohydrate kinase PfkB family
LLZ83_RS06735	COG1349	DNA-binding transcription factor activity
LLZ83_RS06740	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLZ83_RS06740	COG1388	LysM domain
LLZ83_RS06790	COG1837	Belongs to the UPF0109 family
LLZ83_RS06795	COG0228	four-way junction DNA binding
LLZ83_RS06800	COG0577	efflux transmembrane transporter activity
LLZ83_RS06805	COG1136	(ABC) transporter
LLZ83_RS06810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLZ83_RS06820	COG0505	Belongs to the CarA family
LLZ83_RS06830	COG0564	pseudouridine synthase activity
LLZ83_RS06840	COG0583	DNA-binding transcription factor activity
LLZ83_RS06845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLZ83_RS06870	COG1104	cysteine desulfurase activity
LLZ83_RS06880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLZ83_RS06885	COG3679	Belongs to the UPF0342 family
LLZ83_RS06890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LLZ83_RS06895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LLZ83_RS06905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLZ83_RS06910	COG1368	sulfuric ester hydrolase activity
LLZ83_RS06915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLZ83_RS06925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLZ83_RS06930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LLZ83_RS06950	COG2195	Cleaves the N-terminal amino acid of tripeptides
LLZ83_RS06955	COG2244	polysaccharide biosynthetic process
LLZ83_RS06960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLZ83_RS06965	COG1120	ATPase activity
LLZ83_RS06970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLZ83_RS06975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLZ83_RS06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLZ83_RS06990	COG1227	inorganic diphosphatase activity
LLZ83_RS06995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLZ83_RS07000	COG1253	flavin adenine dinucleotide binding
LLZ83_RS07005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LLZ83_RS07010	COG1242	4 iron, 4 sulfur cluster binding
LLZ83_RS07015	COG0671	phosphoesterase, PA-phosphatase related
LLZ83_RS07020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LLZ83_RS07055	COG0297	glycogen (starch) synthase activity
LLZ83_RS07095	COG3475	LICD family
LLZ83_RS07110	COG0463	Glycosyl transferase, family 2
LLZ83_RS07115	COG1215	transferase activity, transferring glycosyl groups
LLZ83_RS07125	COG1091	dTDP-4-dehydrorhamnose reductase activity
LLZ83_RS07130	COG2151	metal-sulfur cluster biosynthetic enzyme
LLZ83_RS07135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LLZ83_RS07140	COG0358	DNA primase activity
LLZ83_RS07145	COG1970	mechanosensitive ion channel activity
LLZ83_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLZ83_RS07170	COG0004	ammonium transporteR
LLZ83_RS07180	COG1054	Belongs to the UPF0176 family
LLZ83_RS07190	COG2271	Major facilitator Superfamily
LLZ83_RS07195	COG0058	SHG alpha-glucan phosphorylase activity
LLZ83_RS07200	COG1640	4-alpha-glucanotransferase
LLZ83_RS07205	COG1609	Transcriptional regulator
LLZ83_RS07215	COG1175	transmembrane transport
LLZ83_RS07220	COG3833	ABC-type maltose transport systems, permease component
LLZ83_RS07225	COG3104	oligopeptide transport
LLZ83_RS07245	COG0438	transferase activity, transferring glycosyl groups
LLZ83_RS07250	COG0653	protein targeting
LLZ83_RS07275	COG1442	glycosyl transferase family 8
LLZ83_RS07280	COG1216	Glycosyl transferase, family 2
LLZ83_RS07280	COG1442	glycosyl transferase family 8
LLZ83_RS07285	COG1442	glycosyl transferase family 8
LLZ83_RS07290	COG1216	Glycosyl transferase, family 2
LLZ83_RS07290	COG1442	glycosyl transferase family 8
LLZ83_RS07295	COG1442	glycosyl transferase family 8
LLZ83_RS07325	COG0765	amino acid transport
LLZ83_RS07330	COG1126	abc transporter atp-binding protein
LLZ83_RS07355	COG2309	aminopeptidase activity
LLZ83_RS07365	COG0154	amidase activity
LLZ83_RS07370	COG1187	pseudouridine synthase activity
LLZ83_RS07375	COG0656	L-ascorbic acid biosynthetic process
LLZ83_RS07380	COG0778	Nitroreductase
LLZ83_RS07385	COG0346	lactoylglutathione lyase activity
LLZ83_RS07390	COG0463	Glycosyl transferase, family 2
LLZ83_RS07395	COG1113	amino acid transport
LLZ83_RS07400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLZ83_RS07405	COG0557	exoribonuclease II activity
LLZ83_RS07420	COG2814	Major facilitator Superfamily
LLZ83_RS07430	COG1131	(ABC) transporter
LLZ83_RS07435	COG0237	dephospho-CoA kinase activity
LLZ83_RS07440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LLZ83_RS07445	COG1396	sequence-specific DNA binding
LLZ83_RS07495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LLZ83_RS07500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLZ83_RS07520	COG1702	phosphate starvation-inducible protein PhoH
LLZ83_RS07535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLZ83_RS07545	COG0233	cytoplasmic translational termination
LLZ83_RS07560	COG0444	Belongs to the ABC transporter superfamily
LLZ83_RS07565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLZ83_RS07570	COG0601	transmembrane transport
LLZ83_RS07575	COG0747	negative chemotaxis
LLZ83_RS07580	COG0081	regulation of translation
LLZ83_RS07585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLZ83_RS07595	COG1473	amidohydrolase
LLZ83_RS07600	COG0583	DNA-binding transcription factor activity
LLZ83_RS07610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LLZ83_RS07615	COG1674	ftsk spoiiie
LLZ83_RS07620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLZ83_RS07645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLZ83_RS07675	COG0673	inositol 2-dehydrogenase activity
LLZ83_RS07690	COG1028	Short-chain dehydrogenase reductase Sdr
LLZ83_RS07740	COG1114	Component of the transport system for branched-chain amino acids
LLZ83_RS07745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLZ83_RS07745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLZ83_RS07760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLZ83_RS07770	COG0708	Exodeoxyribonuclease III
LLZ83_RS07775	COG1393	Belongs to the ArsC family
LLZ83_RS07780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLZ83_RS07785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLZ83_RS07795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLZ83_RS07815	COG0470	DNA polymerase III
LLZ83_RS07825	COG0517	IMP dehydrogenase activity
LLZ83_RS07865	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLZ83_RS07870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LLZ83_RS07880	COG0531	amino acid
LLZ83_RS07885	COG0569	domain protein
LLZ83_RS07900	COG1187	pseudouridine synthase activity
LLZ83_RS07910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LLZ83_RS07915	COG0582	viral genome integration into host DNA
LLZ83_RS07935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LLZ83_RS07950	COG1827	regulation of RNA biosynthetic process
LLZ83_RS07965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLZ83_RS07970	COG1254	Belongs to the acylphosphatase family
LLZ83_RS07975	COG0706	membrane insertase activity
LLZ83_RS07980	COG0765	amino acid transport
LLZ83_RS07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLZ83_RS08000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLZ83_RS08010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLZ83_RS08030	COG1484	DNA-dependent DNA replication
LLZ83_RS08045	COG5002	protein histidine kinase activity
LLZ83_RS08050	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS08060	COG0501	Belongs to the peptidase M48B family
LLZ83_RS08065	COG1704	LemA family
LLZ83_RS08070	COG0357	Ribosomal RNA small subunit methyltransferase G
LLZ83_RS08075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLZ83_RS08080	COG0569	domain protein
LLZ83_RS08090	COG1122	ATPase activity
LLZ83_RS08100	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LLZ83_RS08105	COG1114	Component of the transport system for branched-chain amino acids
LLZ83_RS08110	COG1063	alcohol dehydrogenase
LLZ83_RS08135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLZ83_RS08140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LLZ83_RS08145	COG0217	transcriptional regulatory protein
LLZ83_RS08150	COG2376	Dihydroxyacetone kinase
LLZ83_RS08155	COG1309	transcriptional regulator
LLZ83_RS08160	COG2376	Dihydroxyacetone kinase
LLZ83_RS08165	COG1461	Dihydroxyacetone kinase
LLZ83_RS08170	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LLZ83_RS08175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLZ83_RS08185	COG0789	Transcriptional regulator
LLZ83_RS08190	COG1323	Belongs to the UPF0348 family
LLZ83_RS08200	COG2226	methyltransferase
LLZ83_RS08205	COG0799	negative regulation of ribosome biogenesis
LLZ83_RS08215	COG1713	HD superfamily hydrolase involved in NAD metabolism
LLZ83_RS08220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLZ83_RS08225	COG1534	Rna-binding protein
LLZ83_RS08230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLZ83_RS08235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LLZ83_RS08245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLZ83_RS08250	COG0154	amidase activity
LLZ83_RS08255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLZ83_RS08260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LLZ83_RS08260	COG0574	Belongs to the PEP-utilizing enzyme family
LLZ83_RS08265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LLZ83_RS08270	COG0517	IMP dehydrogenase activity
LLZ83_RS08285	COG1335	isochorismatase
LLZ83_RS08290	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLZ83_RS08295	COG0436	Aminotransferase
LLZ83_RS08300	COG0589	response to stress
LLZ83_RS08305	COG0561	phosphatase activity
LLZ83_RS08310	COG0252	asparaginase activity
LLZ83_RS08320	COG4989	oxidoreductase activity
LLZ83_RS08325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLZ83_RS08330	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLZ83_RS08330	COG3942	CHAP domain
LLZ83_RS08340	COG0736	holo-[acyl-carrier-protein] synthase activity
LLZ83_RS08345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLZ83_RS08355	COG1482	cell wall glycoprotein biosynthetic process
LLZ83_RS08360	COG1940	carbohydrate kinase activity
LLZ83_RS08365	COG2190	(PTS) system
LLZ83_RS08365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS08365	COG1263	PTS System
LLZ83_RS08370	COG1621	beta-fructofuranosidase activity
LLZ83_RS08375	COG1609	Transcriptional regulator
LLZ83_RS08380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLZ83_RS08390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLZ83_RS08395	COG1132	(ABC) transporter
LLZ83_RS08400	COG1132	(ABC) transporter
LLZ83_RS08410	COG1129	ABC transporter
LLZ83_RS08440	COG1021	2,3-dihydroxybenzoate-AMP ligase
LLZ83_RS08450	COG2131	deaminase
LLZ83_RS08455	COG0006	proline dipeptidase activity
LLZ83_RS08465	COG2814	Major facilitator Superfamily
LLZ83_RS08490	COG0629	single-stranded DNA binding
LLZ83_RS08495	COG0360	Binds together with S18 to 16S ribosomal RNA
LLZ83_RS08500	COG1194	a g-specific adenine glycosylase
LLZ83_RS08510	COG3118	belongs to the thioredoxin family
LLZ83_RS08520	COG1193	negative regulation of DNA recombination
LLZ83_RS08535	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLZ83_RS08540	COG0681	Belongs to the peptidase S26 family
LLZ83_RS08545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLZ83_RS08560	COG1882	Formate acetyltransferase
LLZ83_RS08565	COG3576	pyridoxamine 5-phosphate
LLZ83_RS08570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLZ83_RS08585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLZ83_RS08595	COG2814	Major facilitator Superfamily
LLZ83_RS08600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLZ83_RS08605	COG2936	dipeptidyl-peptidase activity
LLZ83_RS08615	COG0142	geranyltranstransferase activity
LLZ83_RS08620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LLZ83_RS08625	COG4988	ABC transporter
LLZ83_RS08630	COG1294	oxidase, subunit
LLZ83_RS08635	COG1271	oxidase subunit
LLZ83_RS08640	COG1252	NADH dehydrogenase
LLZ83_RS08660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLZ83_RS08665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLZ83_RS08670	COG0789	Transcriptional regulator
LLZ83_RS08685	COG2081	HI0933 family
LLZ83_RS08705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LLZ83_RS08710	COG0456	acetyltransferase
LLZ83_RS08715	COG1214	PFAM Peptidase M22, glycoprotease
LLZ83_RS08730	COG3942	CHAP domain
LLZ83_RS08735	COG0174	glutamine synthetase
LLZ83_RS08740	COG0789	Transcriptional regulator
LLZ83_RS08750	COG0126	phosphoglycerate kinase activity
LLZ83_RS08755	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LLZ83_RS08765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLZ83_RS08780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLZ83_RS08805	COG1162	GTPase activity
LLZ83_RS08815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLZ83_RS08830	COG0084	hydrolase, TatD family'
LLZ83_RS08855	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LLZ83_RS08860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLZ83_RS08865	COG1696	Membrane protein involved in D-alanine export
LLZ83_RS08880	COG5002	protein histidine kinase activity
LLZ83_RS08885	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS08895	COG3314	Sporulation integral membrane protein YlbJ
LLZ83_RS08905	COG3448	diguanylate cyclase activity
LLZ83_RS08905	COG4175	Glycine betaine
LLZ83_RS08910	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LLZ83_RS08930	COG1070	Carbohydrate kinase
LLZ83_RS08940	COG3775	system Galactitol-specific IIC component
LLZ83_RS08945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLZ83_RS08955	COG1609	Transcriptional regulator
LLZ83_RS09005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LLZ83_RS09035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LLZ83_RS09040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLZ83_RS09045	COG1428	Deoxynucleoside kinase
LLZ83_RS09055	COG0542	response to heat
LLZ83_RS09060	COG4463	regulation of RNA biosynthetic process
LLZ83_RS09075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLZ83_RS09085	COG0450	alkyl hydroperoxide reductase
LLZ83_RS09100	COG0025	NhaP-type Na H and K H
LLZ83_RS09110	COG1619	proteins homologs of microcin C7 resistance protein MccF
LLZ83_RS09115	COG3590	peptidase
LLZ83_RS09140	COG1609	Transcriptional regulator
LLZ83_RS09150	COG3716	PTS system mannose fructose sorbose family IID component
LLZ83_RS09155	COG3715	PTS system
LLZ83_RS09160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS09165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LLZ83_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
LLZ83_RS09210	COG2176	DNA-directed DNA polymerase activity
LLZ83_RS09215	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLZ83_RS09215	COG1388	LysM domain
LLZ83_RS09230	COG4589	Belongs to the CDS family
LLZ83_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLZ83_RS09240	COG1862	Preprotein translocase
LLZ83_RS09255	COG3493	citrate carrier protein
LLZ83_RS09260	COG3290	protein histidine kinase activity
LLZ83_RS09265	COG4565	transcriptional regulatory protein
LLZ83_RS09270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLZ83_RS09280	COG3842	ATPase activity
LLZ83_RS09350	COG1490	D-aminoacyl-tRNA deacylase activity
LLZ83_RS09360	COG0737	Belongs to the 5'-nucleotidase family
LLZ83_RS09370	COG1363	Peptidase, m42
LLZ83_RS09385	COG2207	Transcriptional regulator
LLZ83_RS09385	COG4753	response regulator
LLZ83_RS09390	COG2972	Histidine kinase
LLZ83_RS09395	COG3716	PTS system mannose fructose sorbose family IID component
LLZ83_RS09400	COG3715	PTS system
LLZ83_RS09425	COG1131	(ABC) transporter
LLZ83_RS09435	COG3279	Response regulator of the LytR AlgR family
LLZ83_RS09445	COG1263	PTS System
LLZ83_RS09445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLZ83_RS09445	COG2190	(PTS) system
LLZ83_RS09450	COG5002	protein histidine kinase activity
LLZ83_RS09455	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS09465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLZ83_RS09470	COG0581	inorganic phosphate transmembrane transporter activity
LLZ83_RS09475	COG0573	inorganic phosphate transmembrane transporter activity
LLZ83_RS09490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLZ83_RS09505	COG0789	Transcriptional regulator
LLZ83_RS09530	COG0456	acetyltransferase
LLZ83_RS09535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLZ83_RS09545	COG0582	viral genome integration into host DNA
LLZ83_RS09605	COG0433	COG0433 Predicted ATPase
LLZ83_RS09625	COG4115	mRNA cleavage
LLZ83_RS09670	COG1674	ftsk spoiiie
LLZ83_RS09715	COG1396	sequence-specific DNA binding
LLZ83_RS09765	COG1914	H( )-stimulated, divalent metal cation uptake system
LLZ83_RS09775	COG1131	(ABC) transporter
LLZ83_RS09815	COG1131	(ABC) transporter
LLZ83_RS09825	COG1396	sequence-specific DNA binding
LLZ83_RS09835	COG1694	Mazg nucleotide pyrophosphohydrolase
LLZ83_RS09865	COG0371	Dehydrogenase
LLZ83_RS09875	COG0646	methionine synthase
LLZ83_RS09875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LLZ83_RS09880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLZ83_RS09890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LLZ83_RS09900	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS09905	COG2205	protein histidine kinase activity
LLZ83_RS09905	COG2770	Histidine kinase
LLZ83_RS09915	COG0495	leucyl-tRNA aminoacylation
LLZ83_RS09920	COG2814	Major facilitator Superfamily
LLZ83_RS09925	COG4667	esterase of the alpha-beta hydrolase superfamily
LLZ83_RS09930	COG1442	glycosyl transferase family 8
LLZ83_RS09935	COG1442	glycosyl transferase family 8
LLZ83_RS09960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLZ83_RS09965	COG0564	pseudouridine synthase activity
LLZ83_RS09985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LLZ83_RS09990	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LLZ83_RS10010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LLZ83_RS10015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLZ83_RS10015	COG1116	anion transmembrane transporter activity
LLZ83_RS10020	COG4120	Belongs to the binding-protein-dependent transport system permease family
LLZ83_RS10030	COG0561	phosphatase activity
LLZ83_RS10035	COG2514	catechol 2,3-dioxygenase activity
LLZ83_RS10045	COG0602	queuosine metabolic process
LLZ83_RS10065	COG1328	CTP reductase activity
LLZ83_RS10080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LLZ83_RS10090	COG1393	Belongs to the ArsC family
LLZ83_RS10095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLZ83_RS10100	COG1058	Belongs to the CinA family
LLZ83_RS10100	COG1546	Belongs to the CinA family
LLZ83_RS10105	COG2818	Glycosylase
LLZ83_RS10120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLZ83_RS10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLZ83_RS10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLZ83_RS10165	COG0124	histidyl-tRNA synthetase
LLZ83_RS10175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLZ83_RS10185	COG0745	RESPONSE REGULATOR receiver
LLZ83_RS10190	COG5002	protein histidine kinase activity
LLZ83_RS10195	COG1288	antiporter activity
LLZ83_RS10205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLZ83_RS10210	COG3852	Histidine kinase
LLZ83_RS10215	COG0784	Response regulator, receiver
LLZ83_RS10220	COG0517	IMP dehydrogenase activity
LLZ83_RS10220	COG1125	glycine betaine transport
LLZ83_RS10225	COG1174	glycine betaine transport
LLZ83_RS10230	COG0392	lysyltransferase activity
LLZ83_RS10230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LLZ83_RS10240	COG3759	membrane
LLZ83_RS10270	COG0305	Participates in initiation and elongation during chromosome replication
LLZ83_RS10285	COG0445	tRNA wobble uridine modification
LLZ83_RS10290	COG2095	MarC family integral membrane protein
LLZ83_RS10295	COG0482	sulfurtransferase activity
LLZ83_RS10300	COG1760	l-serine dehydratase
LLZ83_RS10305	COG1760	l-serine dehydratase
LLZ83_RS10310	COG0741	lytic transglycosylase activity
LLZ83_RS10335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLZ83_RS10340	COG0612	Peptidase, M16
LLZ83_RS10345	COG0612	Peptidase, M16
LLZ83_RS10350	COG2501	S4 domain
LLZ83_RS10370	COG0516	GMP reductase activity
LLZ83_RS10370	COG0517	IMP dehydrogenase activity
LLZ83_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLZ83_RS10395	COG0454	-acetyltransferase
LLZ83_RS10400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLZ83_RS10425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLZ83_RS10430	COG0488	(ABC) transporter
LLZ83_RS10435	COG4485	Bacterial membrane protein, YfhO
LLZ83_RS10455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LLZ83_RS10460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLZ83_RS10465	COG1475	DNA binding