locus-tag	class	description
AMM49_RS00005	COG1475	DNA binding
AMM49_RS00015	COG0592	DNA-directed DNA polymerase activity
AMM49_RS00030	COG0012	GTP binding
AMM49_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMM49_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AMM49_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMM49_RS00325	COG0436	Aminotransferase
AMM49_RS00340	COG0416	fatty acid biosynthetic process
AMM49_RS00345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMM49_RS00350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMM49_RS00355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMM49_RS00370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMM49_RS00380	COG0138	bifunctional purine biosynthesis protein purh
AMM49_RS00405	COG1175	transmembrane transport
AMM49_RS00410	COG0395	ABC-type sugar transport system, permease component
AMM49_RS00425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMM49_RS00435	COG3458	cephalosporin-C deacetylase activity
AMM49_RS00450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMM49_RS00470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMM49_RS00485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMM49_RS00495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMM49_RS00495	COG2755	lipolytic protein G-D-S-L family
AMM49_RS00500	COG1012	belongs to the aldehyde dehydrogenase family
AMM49_RS00500	COG1454	alcohol dehydrogenase
AMM49_RS00505	COG1064	alcohol dehydrogenase
AMM49_RS00515	COG0534	Mate efflux family protein
AMM49_RS00625	COG0201	protein transport
AMM49_RS00630	COG0563	adenylate kinase activity
AMM49_RS00645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMM49_RS00655	COG0202	RNA polymerase activity
AMM49_RS00790	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMM49_RS00795	COG1420	regulation of RNA biosynthetic process
AMM49_RS00805	COG0443	Heat shock 70 kDa protein
AMM49_RS00815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMM49_RS00825	COG0351	phosphomethylpyrimidine kinase
AMM49_RS00830	COG4720	Psort location CytoplasmicMembrane, score
AMM49_RS00840	COG0668	transmembrane transport
AMM49_RS00870	COG0756	dUTP diphosphatase activity
AMM49_RS00885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMM49_RS00895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMM49_RS00900	COG1879	ABC-type sugar transport system periplasmic component
AMM49_RS00905	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMM49_RS00920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMM49_RS00925	COG1609	Transcriptional regulator
AMM49_RS00930	COG0577	efflux transmembrane transporter activity
AMM49_RS00935	COG1136	(ABC) transporter
AMM49_RS00940	COG0745	RESPONSE REGULATOR receiver
AMM49_RS00945	COG5002	protein histidine kinase activity
AMM49_RS00950	COG0137	argininosuccinate synthase activity
AMM49_RS00960	COG0191	fructose-bisphosphate aldolase activity
AMM49_RS00980	COG1461	Dihydroxyacetone kinase
AMM49_RS01000	COG1126	abc transporter atp-binding protein
AMM49_RS01005	COG0765	amino acid transport
AMM49_RS01025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMM49_RS01035	COG0719	Fe-S assembly protein
AMM49_RS01040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMM49_RS01050	COG0719	Fe-S assembly protein
AMM49_RS01055	COG1686	Belongs to the peptidase S11 family
AMM49_RS01060	COG1686	Belongs to the peptidase S11 family
AMM49_RS01065	COG4166	transmembrane transport
AMM49_RS01070	COG0601	transmembrane transport
AMM49_RS01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMM49_RS01080	COG0444	Belongs to the ABC transporter superfamily
AMM49_RS01085	COG4608	Belongs to the ABC transporter superfamily
AMM49_RS01125	COG1121	(ABC) transporter
AMM49_RS01130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMM49_RS01145	COG4499	WXG100 protein secretion system (Wss), protein YukC
AMM49_RS01145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMM49_RS01170	COG1459	type II secretion system
AMM49_RS01210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMM49_RS01215	COG1363	Peptidase, m42
AMM49_RS01230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMM49_RS01235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMM49_RS01250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMM49_RS01270	COG1346	cytolysis
AMM49_RS01280	COG0601	transmembrane transport
AMM49_RS01285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMM49_RS01290	COG1122	ATPase activity
AMM49_RS01300	COG1263	PTS System
AMM49_RS01300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMM49_RS01305	COG0366	Alpha amylase catalytic
AMM49_RS01310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMM49_RS01325	COG3959	Transketolase, thiamine diphosphate binding domain
AMM49_RS01330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMM49_RS01335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMM49_RS01345	COG1185	polyribonucleotide nucleotidyltransferase activity
AMM49_RS01355	COG1045	serine acetyltransferase
AMM49_RS01365	COG0215	cysteine-tRNA ligase activity
AMM49_RS01370	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AMM49_RS01390	COG1476	TRANSCRIPTIONal
AMM49_RS01395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMM49_RS01405	COG0582	viral genome integration into host DNA
AMM49_RS01410	COG1396	sequence-specific DNA binding
AMM49_RS01450	COG5290	Psort location Cytoplasmic, score
AMM49_RS01470	COG1396	sequence-specific DNA binding
AMM49_RS01480	COG2814	Major facilitator Superfamily
AMM49_RS01490	COG1732	Glycine betaine
AMM49_RS01610	COG0519	Catalyzes the synthesis of GMP from XMP
AMM49_RS01655	COG1695	Transcriptional regulator
AMM49_RS01670	COG1755	Isoprenylcysteine carboxyl methyltransferase
AMM49_RS01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMM49_RS01715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMM49_RS01735	COG1131	(ABC) transporter
AMM49_RS01750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMM49_RS01755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMM49_RS01760	COG0275	rRNA processing
AMM49_RS01770	COG0768	penicillin binding
AMM49_RS01780	COG0513	Belongs to the DEAD box helicase family
AMM49_RS01795	COG1126	abc transporter atp-binding protein
AMM49_RS01805	COG0492	ferredoxin-NADP+ reductase activity
AMM49_RS01810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMM49_RS01820	COG3579	cysteine-type endopeptidase activity
AMM49_RS01825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMM49_RS01850	COG0116	Belongs to the methyltransferase superfamily
AMM49_RS01860	COG1854	S-ribosylhomocysteine lyase activity
AMM49_RS01865	COG4372	Transposase
AMM49_RS01865	COG1418	mRNA catabolic process
AMM49_RS01870	COG1131	(ABC) transporter
AMM49_RS01880	COG4585	Histidine kinase
AMM49_RS01885	COG2197	response regulator
AMM49_RS01895	COG0194	GDP metabolic process
AMM49_RS01905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMM49_RS01910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMM49_RS01915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMM49_RS01915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMM49_RS01925	COG2815	serine threonine protein kinase
AMM49_RS01925	COG0515	serine threonine protein kinase
AMM49_RS01935	COG4585	Histidine kinase
AMM49_RS01940	COG2197	response regulator
AMM49_RS01950	COG1098	S1 RNA binding domain
AMM49_RS01955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMM49_RS01960	COG1349	DNA-binding transcription factor activity
AMM49_RS01970	COG1447	Phosphotransferase system cellobiose-specific component IIA
AMM49_RS01980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AMM49_RS01985	COG1882	Formate acetyltransferase
AMM49_RS02005	COG1739	Uncharacterized protein family UPF0029
AMM49_RS02010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AMM49_RS02050	COG0527	aspartate kinase activity
AMM49_RS02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMM49_RS02060	COG1024	Enoyl-CoA hydratase
AMM49_RS02070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMM49_RS02080	COG2070	2-Nitropropane dioxygenase
AMM49_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMM49_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
AMM49_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMM49_RS02110	COG0439	Biotin carboxylase
AMM49_RS02130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMM49_RS02145	COG3716	PTS system mannose fructose sorbose family IID component
AMM49_RS02150	COG3715	PTS system
AMM49_RS02160	COG0561	phosphatase activity
AMM49_RS02175	COG2252	PERMEase
AMM49_RS02180	COG0802	atpase or kinase
AMM49_RS02190	COG1316	TRANSCRIPTIONal
AMM49_RS02200	COG0537	adenosine 5'-monophosphoramidase activity
AMM49_RS02210	COG1131	(ABC) transporter
AMM49_RS02215	COG4473	ABC transporter
AMM49_RS02225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMM49_RS02240	COG0195	Participates in both transcription termination and antitermination
AMM49_RS02245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AMM49_RS02255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMM49_RS02260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMM49_RS02285	COG2860	membrane
AMM49_RS02295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMM49_RS02295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMM49_RS02300	COG1832	CoA-binding protein
AMM49_RS02320	COG5002	protein histidine kinase activity
AMM49_RS02340	COG1268	BioY protein
AMM49_RS02345	COG1234	tRNA 3'-trailer cleavage
AMM49_RS02360	COG0166	Belongs to the GPI family
AMM49_RS02365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMM49_RS02370	COG0705	Rhomboid family
AMM49_RS02370	COG0457	Tetratricopeptide repeat
AMM49_RS02375	COG1744	ABC transporter substrate-binding protein PnrA-like
AMM49_RS02380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMM49_RS02395	COG0706	membrane insertase activity
AMM49_RS02470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMM49_RS02480	COG2153	protein acetylation
AMM49_RS02490	COG1442	glycosyl transferase family 8
AMM49_RS02490	COG1216	Glycosyl transferase, family 2
AMM49_RS02520	COG2801	Transposase and inactivated derivatives
AMM49_RS02550	COG0789	Transcriptional regulator
AMM49_RS02560	COG0656	L-ascorbic acid biosynthetic process
AMM49_RS02640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMM49_RS02665	COG0673	inositol 2-dehydrogenase activity
AMM49_RS02675	COG2315	Protein conserved in bacteria
AMM49_RS02690	COG0742	ribosomal rna small subunit methyltransferase
AMM49_RS02705	COG3480	Lon protease (S16) C-terminal proteolytic domain
AMM49_RS02710	COG0737	Belongs to the 5'-nucleotidase family
AMM49_RS02715	COG4470	Protein conserved in bacteria
AMM49_RS02720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMM49_RS02730	COG1132	(ABC) transporter
AMM49_RS02735	COG1132	(ABC) transporter
AMM49_RS02740	COG0512	Glutamine amidotransferase of anthranilate synthase
AMM49_RS02750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMM49_RS02770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMM49_RS02785	COG1940	carbohydrate kinase activity
AMM49_RS02790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMM49_RS02795	COG1217	gtp-binding protein TYPA
AMM49_RS02805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMM49_RS02830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMM49_RS02840	COG0762	integral membrane protein
AMM49_RS02845	COG2302	S4 RNA-binding domain
AMM49_RS02850	COG3599	regulation of cell shape
AMM49_RS02855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMM49_RS02865	COG0494	nUDIX hydrolase
AMM49_RS02870	COG0542	response to heat
AMM49_RS02875	COG4703	Protein of unknown function (DUF1797)
AMM49_RS02880	COG0765	amino acid transport
AMM49_RS02885	COG1126	abc transporter atp-binding protein
AMM49_RS02890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMM49_RS02900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMM49_RS02905	COG1570	exodeoxyribonuclease VII activity
AMM49_RS02910	COG1722	exodeoxyribonuclease VII activity
AMM49_RS02920	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AMM49_RS02925	COG1438	arginine binding
AMM49_RS02930	COG0497	DNA recombination
AMM49_RS02935	COG1307	EDD domain protein, DegV family
AMM49_RS02940	COG2755	lipolytic protein G-D-S-L family
AMM49_RS02985	COG1078	dGTPase activity
AMM49_RS03010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMM49_RS03020	COG2884	Cell division ATP-binding protein ftsE
AMM49_RS03025	COG2177	Part of the ABC transporter FtsEX involved in
AMM49_RS03035	COG2801	Transposase and inactivated derivatives
AMM49_RS03055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMM49_RS03055	COG1199	ATP-dependent helicase activity
AMM49_RS03060	COG0436	Aminotransferase
AMM49_RS03065	COG0017	Asparaginyl-tRNA synthetase
AMM49_RS03085	COG1660	Displays ATPase and GTPase activities
AMM49_RS03110	COG0254	rRNA binding
AMM49_RS03115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMM49_RS03120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMM49_RS03125	COG0716	FMN binding
AMM49_RS03130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AMM49_RS03130	COG1605	Chorismate mutase
AMM49_RS03135	COG0038	chloride channel
AMM49_RS03140	COG0335	large ribosomal subunit rRNA binding
AMM49_RS03175	COG1136	(ABC) transporter
AMM49_RS03190	COG5002	protein histidine kinase activity
AMM49_RS03205	COG0772	Belongs to the SEDS family
AMM49_RS03225	COG0560	Phosphoserine phosphatase
AMM49_RS03240	COG0148	phosphopyruvate hydratase activity
AMM49_RS03260	COG1316	TRANSCRIPTIONal
AMM49_RS03275	COG3700	Belongs to the class B bacterial acid phosphatase family
AMM49_RS03370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMM49_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
AMM49_RS03405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMM49_RS03410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMM49_RS03430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMM49_RS03435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMM49_RS03455	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMM49_RS03455	COG3064	Membrane
AMM49_RS03475	COG3590	peptidase
AMM49_RS03480	COG3590	peptidase
AMM49_RS03525	COG1136	(ABC) transporter
AMM49_RS03540	COG0586	Pfam SNARE associated Golgi protein
AMM49_RS03545	COG4619	ABC transporter
AMM49_RS03550	COG0390	transport system, permease component
AMM49_RS03560	COG0583	DNA-binding transcription factor activity
AMM49_RS03585	COG3250	beta-galactosidase activity
AMM49_RS03590	COG2186	Transcriptional regulator
AMM49_RS03595	COG0800	Aldolase
AMM49_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
AMM49_RS03630	COG1609	Transcriptional regulator
AMM49_RS03645	COG0438	transferase activity, transferring glycosyl groups
AMM49_RS03670	COG0765	amino acid transport
AMM49_RS03675	COG0765	amino acid transport
AMM49_RS03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMM49_RS03685	COG1126	abc transporter atp-binding protein
AMM49_RS03690	COG0745	RESPONSE REGULATOR receiver
AMM49_RS03695	COG5002	protein histidine kinase activity
AMM49_RS03700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMM49_RS03705	COG2832	Protein of unknown function (DUF454)
AMM49_RS03715	COG1196	nuclear chromosome segregation
AMM49_RS03745	COG4372	Transposase
AMM49_RS03790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMM49_RS03790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMM49_RS03835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMM49_RS03850	COG0270	DNA (cytosine-5-)-methyltransferase activity
AMM49_RS03890	COG4695	Portal protein
AMM49_RS03895	COG0740	serine-type endopeptidase activity
AMM49_RS03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMM49_RS03960	COG1388	LysM domain
AMM49_RS03980	COG0561	phosphatase activity
AMM49_RS03985	COG0561	phosphatase activity
AMM49_RS03990	COG0552	protein localization to endoplasmic reticulum
AMM49_RS03995	COG3344	reverse transcriptase
AMM49_RS04005	COG3689	TIGRFAM TIGR03943 family protein
AMM49_RS04010	COG0701	Predicted permease
AMM49_RS04025	COG2183	response to ionizing radiation
AMM49_RS04030	COG3091	SprT-like family
AMM49_RS04035	COG1983	PspC domain protein
AMM49_RS04070	COG0826	peptidase U32
AMM49_RS04075	COG4443	Transcriptional Coactivator p15 (PC4)
AMM49_RS04085	COG1914	H( )-stimulated, divalent metal cation uptake system
AMM49_RS04125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMM49_RS04150	COG1164	Oligoendopeptidase f
AMM49_RS04160	COG0772	Belongs to the SEDS family
AMM49_RS04180	COG0768	penicillin binding
AMM49_RS04195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMM49_RS04200	COG2223	nitrite transmembrane transporter activity
AMM49_RS04225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMM49_RS04230	COG2011	ABC-type metal ion transport system permease component
AMM49_RS04235	COG1464	Belongs to the NlpA lipoprotein family
AMM49_RS04240	COG0513	Belongs to the DEAD box helicase family
AMM49_RS04250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMM49_RS04255	COG0204	Acyl-transferase
AMM49_RS04260	COG1555	photosystem II stabilization
AMM49_RS04260	COG1596	polysaccharide export
AMM49_RS04265	COG0658	competence protein
AMM49_RS04265	COG2333	competence protein COMEC
AMM49_RS04270	COG0561	phosphatase activity
AMM49_RS04275	COG1609	Transcriptional regulator
AMM49_RS04280	COG0657	acetylesterase activity
AMM49_RS04285	COG2226	methyltransferase
AMM49_RS04295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMM49_RS04300	COG3711	transcriptional antiterminator
AMM49_RS04305	COG1263	PTS System
AMM49_RS04305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMM49_RS04305	COG2190	(PTS) system
AMM49_RS04315	COG3835	regulator
AMM49_RS04320	COG1929	Belongs to the glycerate kinase type-1 family
AMM49_RS04325	COG2610	gluconate transmembrane transporter activity
AMM49_RS04335	COG1846	Transcriptional regulator
AMM49_RS04340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMM49_RS04350	COG0363	glucosamine-6-phosphate deaminase activity
AMM49_RS04355	COG0435	Glutathione S-transferase
AMM49_RS04360	COG1187	pseudouridine synthase activity
AMM49_RS04380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMM49_RS04385	COG4122	O-methyltransferase activity
AMM49_RS04390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMM49_RS04395	COG4894	glucomannan catabolic process
AMM49_RS04400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMM49_RS04410	COG1442	glycosyl transferase family 8
AMM49_RS04425	COG1476	TRANSCRIPTIONal
AMM49_RS04440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMM49_RS04445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMM49_RS04450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMM49_RS04465	COG1012	belongs to the aldehyde dehydrogenase family
AMM49_RS04470	COG0726	polysaccharide deacetylase
AMM49_RS04475	COG0513	Belongs to the DEAD box helicase family
AMM49_RS04485	COG1956	GAF domain-containing protein
AMM49_RS04490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMM49_RS04500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMM49_RS04500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMM49_RS04530	COG4721	ABC-type cobalt transport system, permease component
AMM49_RS04535	COG1122	ATPase activity
AMM49_RS04545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AMM49_RS04565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMM49_RS04575	COG4109	DRTGG domain
AMM49_RS04580	COG0024	Methionine aminopeptidase
AMM49_RS04590	COG2246	polysaccharide biosynthetic process
AMM49_RS04595	COG4708	membrane
AMM49_RS04600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMM49_RS04605	COG1597	lipid kinase activity
AMM49_RS04610	COG1523	belongs to the glycosyl hydrolase 13 family
AMM49_RS04670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMM49_RS04680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMM49_RS04705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMM49_RS04705	COG0072	phenylalanine-tRNA ligase activity
AMM49_RS04710	COG2321	neutral zinc metallopeptidase
AMM49_RS04715	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AMM49_RS04720	COG1074	ATP-dependent DNA helicase activity
AMM49_RS04730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMM49_RS04735	COG0488	(ABC) transporter
AMM49_RS04740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMM49_RS04745	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMM49_RS04745	COG0022	dehydrogenase e1 component
AMM49_RS04750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMM49_RS04760	COG0095	Lipoate-protein ligase
AMM49_RS04765	COG3344	reverse transcriptase
AMM49_RS04775	COG3442	glutamine amidotransferase
AMM49_RS04780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMM49_RS04785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AMM49_RS04810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMM49_RS04820	COG0647	UMP catabolic process
AMM49_RS04830	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AMM49_RS04835	COG1518	maintenance of DNA repeat elements
AMM49_RS04840	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AMM49_RS04860	COG0481	GTPase activity
AMM49_RS04870	COG1418	mRNA catabolic process
AMM49_RS04875	COG0456	acetyltransferase
AMM49_RS04885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMM49_RS04915	COG1131	(ABC) transporter
AMM49_RS04920	COG1725	Transcriptional regulator
AMM49_RS04930	COG0205	6-phosphofructokinase activity
AMM49_RS04935	COG0469	pyruvate kinase activity
AMM49_RS04945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMM49_RS04950	COG2824	Alkylphosphonate utilization operon protein PhnA
AMM49_RS04955	COG0765	amino acid transport
AMM49_RS04960	COG1126	abc transporter atp-binding protein
AMM49_RS04975	COG1072	(Pantothenic acid kinase))
AMM49_RS04980	COG2813	Specifically methylates the guanine in position
AMM49_RS04990	COG1744	ABC transporter substrate-binding protein PnrA-like
AMM49_RS04995	COG3845	ABC transporter
AMM49_RS05000	COG4603	Belongs to the binding-protein-dependent transport system permease family
AMM49_RS05005	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMM49_RS05025	COG3764	Sortase (surface protein transpeptidase)
AMM49_RS05030	COG0346	lactoylglutathione lyase activity
AMM49_RS05060	COG1674	ftsk spoiiie
AMM49_RS05065	COG2946	Replication initiation factor
AMM49_RS05110	COG0791	NLP P60 protein
AMM49_RS05110	COG0741	lytic transglycosylase activity
AMM49_RS05145	COG0582	viral genome integration into host DNA
AMM49_RS05155	COG2188	Transcriptional regulator
AMM49_RS05170	COG1464	Belongs to the NlpA lipoprotein family
AMM49_RS05185	COG1136	(ABC) transporter
AMM49_RS05195	COG0745	RESPONSE REGULATOR receiver
AMM49_RS05200	COG5002	protein histidine kinase activity
AMM49_RS05205	COG4974	Belongs to the 'phage' integrase family
AMM49_RS05210	COG4166	transmembrane transport
AMM49_RS05225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMM49_RS05230	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AMM49_RS05235	COG5002	protein histidine kinase activity
AMM49_RS05240	COG0745	RESPONSE REGULATOR receiver
AMM49_RS05250	COG0704	Plays a role in the regulation of phosphate uptake
AMM49_RS05255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMM49_RS05260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMM49_RS05265	COG0581	inorganic phosphate transmembrane transporter activity
AMM49_RS05270	COG0573	inorganic phosphate transmembrane transporter activity
AMM49_RS05280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AMM49_RS05280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMM49_RS05285	COG0483	inositol monophosphate 1-phosphatase activity
AMM49_RS05290	COG4476	Belongs to the UPF0223 family
AMM49_RS05300	COG0196	riboflavin kinase activity
AMM49_RS05305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMM49_RS05335	COG1136	(ABC) transporter
AMM49_RS05340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMM49_RS05345	COG0758	DNA mediated transformation
AMM49_RS05360	COG4604	ABC transporter, ATP-binding protein
AMM49_RS05365	COG4605	iron ion homeostasis
AMM49_RS05370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMM49_RS05375	COG0110	maltose O-acetyltransferase activity
AMM49_RS05385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMM49_RS05390	COG1376	ErfK ybiS ycfS ynhG family protein
AMM49_RS05395	COG1966	Carbon starvation protein
AMM49_RS05400	COG3279	Response regulator of the LytR AlgR family
AMM49_RS05405	COG3275	phosphorelay sensor kinase activity
AMM49_RS05495	COG0505	Belongs to the CarA family
AMM49_RS05510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMM49_RS05525	COG0488	(ABC) transporter
AMM49_RS05535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMM49_RS05545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMM49_RS05585	COG0095	Lipoate-protein ligase
AMM49_RS05595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMM49_RS05600	COG4684	Psort location CytoplasmicMembrane, score
AMM49_RS05605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMM49_RS05615	COG1132	(ABC) transporter
AMM49_RS05645	COG2890	protein-(glutamine-N5) methyltransferase activity
AMM49_RS05650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMM49_RS05660	COG1942	4-Oxalocrotonate Tautomerase
AMM49_RS05675	COG0431	NADPH-dependent FMN reductase
AMM49_RS05675	COG1053	succinate dehydrogenase
AMM49_RS05675	COG3976	FMN-binding domain protein
AMM49_RS05685	COG2233	PERMEase
AMM49_RS05700	COG0477	Major facilitator Superfamily
AMM49_RS05715	COG4221	oxidoreductase activity
AMM49_RS05720	COG4221	oxidoreductase activity
AMM49_RS05725	COG0280	phosphate acetyltransferase
AMM49_RS05730	COG0564	pseudouridine synthase activity
AMM49_RS05740	COG2357	RelA SpoT domain protein
AMM49_RS05755	COG1104	cysteine desulfurase activity
AMM49_RS05765	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AMM49_RS05770	COG2003	Belongs to the UPF0758 family
AMM49_RS05775	COG0628	permease
AMM49_RS05780	COG2723	6-phospho-beta-galactosidase activity
AMM49_RS05790	COG0561	phosphatase activity
AMM49_RS05800	COG0038	chloride channel
AMM49_RS05810	COG1177	transmembrane transport
AMM49_RS05815	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMM49_RS05825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMM49_RS05850	COG0285	dihydrofolate synthase activity
AMM49_RS05855	COG2962	Rard protein
AMM49_RS05880	COG1012	belongs to the aldehyde dehydrogenase family
AMM49_RS05955	COG2261	transglycosylase associated protein
AMM49_RS05980	COG1115	amino acid carrier protein
AMM49_RS05985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AMM49_RS05990	COG1380	Effector of murein hydrolase LrgA
AMM49_RS05995	COG1346	cytolysis
AMM49_RS06010	COG0539	negative regulation of cytoplasmic translation
AMM49_RS06030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMM49_RS06040	COG0187	DNA topoisomerase II activity
AMM49_RS06045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMM49_RS06050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMM49_RS06060	COG2755	lipolytic protein G-D-S-L family
AMM49_RS06060	COG1083	cytidylyl-transferase
AMM49_RS06075	COG2089	acid synthase
AMM49_RS06090	COG1216	Glycosyl transferase, family 2
AMM49_RS06090	COG1442	glycosyl transferase family 8
AMM49_RS06095	COG1442	glycosyl transferase family 8
AMM49_RS06095	COG1216	Glycosyl transferase, family 2
AMM49_RS06110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMM49_RS06115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMM49_RS06135	COG1316	TRANSCRIPTIONal
AMM49_RS06145	COG2801	Transposase and inactivated derivatives
AMM49_RS06170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMM49_RS06205	COG3842	ATPase activity
AMM49_RS06220	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AMM49_RS06225	COG3527	Alpha-acetolactate decarboxylase
AMM49_RS06230	COG0028	Belongs to the TPP enzyme family
AMM49_RS06235	COG0457	Tetratricopeptide repeat
AMM49_RS06240	COG0628	permease
AMM49_RS06250	COG1051	belongs to the nudix hydrolase family
AMM49_RS06255	COG5492	domain, Protein
AMM49_RS06260	COG1088	dTDP-glucose 4,6-dehydratase activity
AMM49_RS06270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMM49_RS06275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMM49_RS06285	COG2384	SAM-dependent methyltransferase
AMM49_RS06305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AMM49_RS06305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMM49_RS06310	COG0300	oxidoreductase activity
AMM49_RS06325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMM49_RS06330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMM49_RS06355	COG1573	uracil-dna glycosylase
AMM49_RS06360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMM49_RS06370	COG0584	glycerophosphoryl diester phosphodiesterase
AMM49_RS06375	COG2801	Transposase and inactivated derivatives
AMM49_RS06395	COG0534	Mate efflux family protein
AMM49_RS06430	COG2801	Transposase and inactivated derivatives
AMM49_RS06440	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMM49_RS06450	COG3344	reverse transcriptase
AMM49_RS06530	COG0515	serine threonine protein kinase
AMM49_RS06560	COG2040	homocysteine
AMM49_RS06565	COG0833	amino acid
AMM49_RS06600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMM49_RS06610	COG3425	synthase
AMM49_RS06625	COG1272	protein, Hemolysin III
AMM49_RS06670	COG0745	RESPONSE REGULATOR receiver
AMM49_RS06675	COG2357	RelA SpoT domain protein
AMM49_RS06680	COG1132	(ABC) transporter
AMM49_RS06695	COG0737	Belongs to the 5'-nucleotidase family
AMM49_RS06700	COG0242	peptide deformylase activity
AMM49_RS06705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMM49_RS06715	COG1132	(ABC) transporter
AMM49_RS06730	COG0488	(ABC) transporter
AMM49_RS06760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMM49_RS06760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMM49_RS06760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMM49_RS06765	COG1105	Belongs to the carbohydrate kinase PfkB family
AMM49_RS06770	COG1349	DNA-binding transcription factor activity
AMM49_RS06825	COG1837	Belongs to the UPF0109 family
AMM49_RS06830	COG0228	four-way junction DNA binding
AMM49_RS06835	COG0577	efflux transmembrane transporter activity
AMM49_RS06840	COG1136	(ABC) transporter
AMM49_RS06845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMM49_RS06850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMM49_RS06855	COG0505	Belongs to the CarA family
AMM49_RS06865	COG0564	pseudouridine synthase activity
AMM49_RS06875	COG0583	DNA-binding transcription factor activity
AMM49_RS06880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMM49_RS06905	COG1104	cysteine desulfurase activity
AMM49_RS06915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMM49_RS06920	COG1442	glycosyl transferase family 8
AMM49_RS06950	COG1073	alpha beta
AMM49_RS06990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMM49_RS06995	COG1368	sulfuric ester hydrolase activity
AMM49_RS07000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMM49_RS07010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMM49_RS07040	COG2244	polysaccharide biosynthetic process
AMM49_RS07045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMM49_RS07050	COG1120	ATPase activity
AMM49_RS07055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMM49_RS07060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMM49_RS07065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMM49_RS07080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMM49_RS07085	COG1253	flavin adenine dinucleotide binding
AMM49_RS07095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AMM49_RS07100	COG1242	4 iron, 4 sulfur cluster binding
AMM49_RS07105	COG0671	phosphoesterase, PA-phosphatase related
AMM49_RS07110	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AMM49_RS07140	COG0681	Belongs to the peptidase S26 family
AMM49_RS07150	COG0297	glycogen (starch) synthase activity
AMM49_RS07190	COG3475	LICD family
AMM49_RS07205	COG0463	Glycosyl transferase, family 2
AMM49_RS07210	COG1215	transferase activity, transferring glycosyl groups
AMM49_RS07220	COG1091	dTDP-4-dehydrorhamnose reductase activity
AMM49_RS07225	COG2151	metal-sulfur cluster biosynthetic enzyme
AMM49_RS07230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMM49_RS07235	COG0358	DNA primase activity
AMM49_RS07240	COG1970	mechanosensitive ion channel activity
AMM49_RS07245	COG2801	Transposase and inactivated derivatives
AMM49_RS07265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMM49_RS07270	COG0004	ammonium transporteR
AMM49_RS07280	COG1054	Belongs to the UPF0176 family
AMM49_RS07290	COG2271	Major facilitator Superfamily
AMM49_RS07295	COG0058	SHG alpha-glucan phosphorylase activity
AMM49_RS07300	COG1640	4-alpha-glucanotransferase
AMM49_RS07305	COG1609	Transcriptional regulator
AMM49_RS07315	COG1175	transmembrane transport
AMM49_RS07320	COG3833	ABC-type maltose transport systems, permease component
AMM49_RS07325	COG3104	oligopeptide transport
AMM49_RS07335	COG2801	Transposase and inactivated derivatives
AMM49_RS07365	COG0765	amino acid transport
AMM49_RS07370	COG1126	abc transporter atp-binding protein
AMM49_RS07395	COG2309	aminopeptidase activity
AMM49_RS07415	COG1187	pseudouridine synthase activity
AMM49_RS07420	COG0656	L-ascorbic acid biosynthetic process
AMM49_RS07425	COG0778	Nitroreductase
AMM49_RS07430	COG0346	lactoylglutathione lyase activity
AMM49_RS07435	COG0463	Glycosyl transferase, family 2
AMM49_RS07440	COG1113	amino acid transport
AMM49_RS07445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMM49_RS07450	COG0557	exoribonuclease II activity
AMM49_RS07460	COG2814	Major facilitator Superfamily
AMM49_RS07470	COG1131	(ABC) transporter
AMM49_RS07480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMM49_RS07485	COG1396	sequence-specific DNA binding
AMM49_RS07525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMM49_RS07530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMM49_RS07550	COG1702	phosphate starvation-inducible protein PhoH
AMM49_RS07575	COG0233	cytoplasmic translational termination
AMM49_RS07590	COG0444	Belongs to the ABC transporter superfamily
AMM49_RS07595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMM49_RS07600	COG0601	transmembrane transport
AMM49_RS07605	COG0747	negative chemotaxis
AMM49_RS07610	COG0081	regulation of translation
AMM49_RS07630	COG1473	amidohydrolase
AMM49_RS07635	COG0583	DNA-binding transcription factor activity
AMM49_RS07650	COG2801	Transposase and inactivated derivatives
AMM49_RS07655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMM49_RS07660	COG1674	ftsk spoiiie
AMM49_RS07665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMM49_RS07690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMM49_RS07720	COG0673	inositol 2-dehydrogenase activity
AMM49_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
AMM49_RS07775	COG1114	Component of the transport system for branched-chain amino acids
AMM49_RS07780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMM49_RS07780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMM49_RS07795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AMM49_RS07805	COG0708	Exodeoxyribonuclease III
AMM49_RS07810	COG1393	Belongs to the ArsC family
AMM49_RS07815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMM49_RS07830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMM49_RS07850	COG0470	DNA polymerase III
AMM49_RS07865	COG0517	IMP dehydrogenase activity
AMM49_RS07885	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMM49_RS07905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMM49_RS07910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMM49_RS07920	COG0531	amino acid
AMM49_RS07925	COG0569	domain protein
AMM49_RS07930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMM49_RS07940	COG1187	pseudouridine synthase activity
AMM49_RS07990	COG1827	regulation of RNA biosynthetic process
AMM49_RS08005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMM49_RS08010	COG1254	Belongs to the acylphosphatase family
AMM49_RS08020	COG0765	amino acid transport
AMM49_RS08025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMM49_RS08040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMM49_RS08070	COG1484	DNA-dependent DNA replication
AMM49_RS08085	COG5002	protein histidine kinase activity
AMM49_RS08090	COG0745	RESPONSE REGULATOR receiver
AMM49_RS08105	COG1704	LemA family
AMM49_RS08110	COG0357	Ribosomal RNA small subunit methyltransferase G
AMM49_RS08115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMM49_RS08120	COG0569	domain protein
AMM49_RS08145	COG1114	Component of the transport system for branched-chain amino acids
AMM49_RS08150	COG1063	alcohol dehydrogenase
AMM49_RS08175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMM49_RS08180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMM49_RS08185	COG0217	transcriptional regulatory protein
AMM49_RS08215	COG2376	Dihydroxyacetone kinase
AMM49_RS08220	COG1309	transcriptional regulator
AMM49_RS08225	COG2376	Dihydroxyacetone kinase
AMM49_RS08230	COG1461	Dihydroxyacetone kinase
AMM49_RS08235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AMM49_RS08240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMM49_RS08265	COG2226	methyltransferase
AMM49_RS08270	COG0799	negative regulation of ribosome biogenesis
AMM49_RS08280	COG1713	HD superfamily hydrolase involved in NAD metabolism
AMM49_RS08285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMM49_RS08290	COG1534	Rna-binding protein
AMM49_RS08295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMM49_RS08300	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AMM49_RS08325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMM49_RS08325	COG0574	Belongs to the PEP-utilizing enzyme family
AMM49_RS08335	COG0517	IMP dehydrogenase activity
AMM49_RS08345	COG1335	isochorismatase
AMM49_RS08350	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AMM49_RS08355	COG0436	Aminotransferase
AMM49_RS08360	COG0589	response to stress
AMM49_RS08365	COG0561	phosphatase activity
AMM49_RS08370	COG0252	asparaginase activity
AMM49_RS08380	COG4989	oxidoreductase activity
AMM49_RS08385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMM49_RS08390	COG3942	CHAP domain
AMM49_RS08390	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMM49_RS08400	COG0736	holo-[acyl-carrier-protein] synthase activity
AMM49_RS08405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMM49_RS08415	COG1482	cell wall glycoprotein biosynthetic process
AMM49_RS08420	COG1940	carbohydrate kinase activity
AMM49_RS08425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMM49_RS08425	COG2190	(PTS) system
AMM49_RS08425	COG1263	PTS System
AMM49_RS08430	COG1621	beta-fructofuranosidase activity
AMM49_RS08435	COG1609	Transcriptional regulator
AMM49_RS08440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMM49_RS08450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMM49_RS08470	COG2131	deaminase
AMM49_RS08475	COG0006	proline dipeptidase activity
AMM49_RS08485	COG2814	Major facilitator Superfamily
AMM49_RS08510	COG0629	single-stranded DNA binding
AMM49_RS08515	COG0360	Binds together with S18 to 16S ribosomal RNA
AMM49_RS08520	COG1194	a g-specific adenine glycosylase
AMM49_RS08530	COG3118	belongs to the thioredoxin family
AMM49_RS08560	COG0681	Belongs to the peptidase S26 family
AMM49_RS08565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMM49_RS08580	COG1882	Formate acetyltransferase
AMM49_RS08590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMM49_RS08605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMM49_RS08615	COG2814	Major facilitator Superfamily
AMM49_RS08620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMM49_RS08635	COG0142	geranyltranstransferase activity
AMM49_RS08640	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMM49_RS08645	COG4988	ABC transporter
AMM49_RS08650	COG1294	oxidase, subunit
AMM49_RS08655	COG1271	oxidase subunit
AMM49_RS08660	COG1252	NADH dehydrogenase
AMM49_RS08675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMM49_RS08680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMM49_RS08700	COG2081	HI0933 family
AMM49_RS08725	COG0456	acetyltransferase
AMM49_RS08730	COG1214	PFAM Peptidase M22, glycoprotease
AMM49_RS08745	COG3942	CHAP domain
AMM49_RS08750	COG0174	glutamine synthetase
AMM49_RS08755	COG0789	Transcriptional regulator
AMM49_RS08770	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AMM49_RS08795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMM49_RS08845	COG0084	hydrolase, TatD family'
AMM49_RS08870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AMM49_RS08875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMM49_RS08880	COG1696	Membrane protein involved in D-alanine export
AMM49_RS08900	COG0745	RESPONSE REGULATOR receiver
AMM49_RS08910	COG3314	Sporulation integral membrane protein YlbJ
AMM49_RS08925	COG3448	diguanylate cyclase activity
AMM49_RS08925	COG4175	Glycine betaine
AMM49_RS08930	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMM49_RS08950	COG1070	Carbohydrate kinase
AMM49_RS08960	COG3775	system Galactitol-specific IIC component
AMM49_RS08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMM49_RS08975	COG1609	Transcriptional regulator
AMM49_RS09025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMM49_RS09060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMM49_RS09065	COG1428	Deoxynucleoside kinase
AMM49_RS09075	COG0542	response to heat
AMM49_RS09080	COG4463	regulation of RNA biosynthetic process
AMM49_RS09090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMM49_RS09100	COG0450	alkyl hydroperoxide reductase
AMM49_RS09115	COG0025	NhaP-type Na H and K H
AMM49_RS09125	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMM49_RS09130	COG3590	peptidase
AMM49_RS09155	COG1609	Transcriptional regulator
AMM49_RS09165	COG3716	PTS system mannose fructose sorbose family IID component
AMM49_RS09170	COG3715	PTS system
AMM49_RS09175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMM49_RS09180	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AMM49_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
AMM49_RS09225	COG2176	DNA-directed DNA polymerase activity
AMM49_RS09230	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMM49_RS09230	COG1388	LysM domain
AMM49_RS09245	COG4589	Belongs to the CDS family
AMM49_RS09250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMM49_RS09255	COG1862	Preprotein translocase
AMM49_RS09270	COG3493	citrate carrier protein
AMM49_RS09275	COG3290	protein histidine kinase activity
AMM49_RS09280	COG4565	transcriptional regulatory protein
AMM49_RS09285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMM49_RS09295	COG3842	ATPase activity
AMM49_RS09320	COG2801	Transposase and inactivated derivatives
AMM49_RS09375	COG1490	D-aminoacyl-tRNA deacylase activity
AMM49_RS09385	COG0737	Belongs to the 5'-nucleotidase family
AMM49_RS09395	COG1363	Peptidase, m42
AMM49_RS09415	COG2207	Transcriptional regulator
AMM49_RS09415	COG4753	response regulator
AMM49_RS09420	COG2972	Histidine kinase
AMM49_RS09425	COG3716	PTS system mannose fructose sorbose family IID component
AMM49_RS09430	COG3715	PTS system
AMM49_RS09455	COG1131	(ABC) transporter
AMM49_RS09470	COG3290	protein histidine kinase activity
AMM49_RS09475	COG3279	Response regulator of the LytR AlgR family
AMM49_RS09485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMM49_RS09485	COG2190	(PTS) system
AMM49_RS09485	COG1263	PTS System
AMM49_RS09490	COG5002	protein histidine kinase activity
AMM49_RS09495	COG0745	RESPONSE REGULATOR receiver
AMM49_RS09505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMM49_RS09510	COG0581	inorganic phosphate transmembrane transporter activity
AMM49_RS09515	COG0573	inorganic phosphate transmembrane transporter activity
AMM49_RS09530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMM49_RS09545	COG0789	Transcriptional regulator
AMM49_RS09565	COG0456	acetyltransferase
AMM49_RS09570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMM49_RS09645	COG1131	(ABC) transporter
AMM49_RS09655	COG1396	sequence-specific DNA binding
AMM49_RS09660	COG2801	Transposase and inactivated derivatives
AMM49_RS09675	COG1694	Mazg nucleotide pyrophosphohydrolase
AMM49_RS09690	COG2897	thiosulfate sulfurtransferase activity
AMM49_RS09705	COG0371	Dehydrogenase
AMM49_RS09715	COG0646	methionine synthase
AMM49_RS09715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMM49_RS09720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMM49_RS09730	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMM49_RS09765	COG2814	Major facilitator Superfamily
AMM49_RS09770	COG4667	esterase of the alpha-beta hydrolase superfamily
AMM49_RS09775	COG1442	glycosyl transferase family 8
AMM49_RS09780	COG1442	glycosyl transferase family 8
AMM49_RS09800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMM49_RS09805	COG0564	pseudouridine synthase activity
AMM49_RS09825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMM49_RS09830	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AMM49_RS09850	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMM49_RS09855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMM49_RS09855	COG1116	anion transmembrane transporter activity
AMM49_RS09860	COG4120	Belongs to the binding-protein-dependent transport system permease family
AMM49_RS09870	COG0561	phosphatase activity
AMM49_RS09875	COG2514	catechol 2,3-dioxygenase activity
AMM49_RS09885	COG0602	queuosine metabolic process
AMM49_RS09905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMM49_RS09905	COG1328	CTP reductase activity
AMM49_RS09925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMM49_RS09935	COG1393	Belongs to the ArsC family
AMM49_RS09940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMM49_RS09945	COG1058	Belongs to the CinA family
AMM49_RS09945	COG1546	Belongs to the CinA family
AMM49_RS09950	COG2818	Glycosylase
AMM49_RS09985	COG0018	arginyl-trna synthetase
AMM49_RS09995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AMM49_RS10000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AMM49_RS10005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMM49_RS10010	COG0124	histidyl-tRNA synthetase
AMM49_RS10020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMM49_RS10070	COG4974	Belongs to the 'phage' integrase family
AMM49_RS10080	COG0745	RESPONSE REGULATOR receiver
AMM49_RS10085	COG5002	protein histidine kinase activity
AMM49_RS10090	COG1288	antiporter activity
AMM49_RS10100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMM49_RS10105	COG3852	Histidine kinase
AMM49_RS10110	COG0784	Response regulator, receiver
AMM49_RS10115	COG1125	glycine betaine transport
AMM49_RS10115	COG0517	IMP dehydrogenase activity
AMM49_RS10120	COG1174	glycine betaine transport
AMM49_RS10125	COG0392	lysyltransferase activity
AMM49_RS10125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMM49_RS10135	COG3759	membrane
AMM49_RS10165	COG0305	Participates in initiation and elongation during chromosome replication
AMM49_RS10180	COG0445	tRNA wobble uridine modification
AMM49_RS10185	COG2095	MarC family integral membrane protein
AMM49_RS10190	COG0482	sulfurtransferase activity
AMM49_RS10195	COG1760	l-serine dehydratase
AMM49_RS10200	COG1760	l-serine dehydratase
AMM49_RS10205	COG0741	lytic transglycosylase activity
AMM49_RS10230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMM49_RS10235	COG0612	Peptidase, M16
AMM49_RS10240	COG0612	Peptidase, M16
AMM49_RS10245	COG2501	S4 domain
AMM49_RS10265	COG0516	GMP reductase activity
AMM49_RS10265	COG0517	IMP dehydrogenase activity
AMM49_RS10275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMM49_RS10320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AMM49_RS10325	COG0488	(ABC) transporter
AMM49_RS10330	COG4485	Bacterial membrane protein, YfhO
AMM49_RS10350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMM49_RS10355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain