locus-tag	class	description
EN73_RS00005	COG1475	DNA binding
EN73_RS00015	COG0592	DNA-directed DNA polymerase activity
EN73_RS00020	COG1597	lipid kinase activity
EN73_RS00035	COG0012	GTP binding
EN73_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EN73_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EN73_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EN73_RS00265	COG0436	Aminotransferase
EN73_RS00280	COG0416	fatty acid biosynthetic process
EN73_RS00285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EN73_RS00295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EN73_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EN73_RS00320	COG0138	bifunctional purine biosynthesis protein purh
EN73_RS00345	COG1175	transmembrane transport
EN73_RS00350	COG0395	ABC-type sugar transport system, permease component
EN73_RS00365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EN73_RS00375	COG3458	cephalosporin-C deacetylase activity
EN73_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EN73_RS00410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EN73_RS00425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EN73_RS00435	COG2755	lipolytic protein G-D-S-L family
EN73_RS00435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EN73_RS00440	COG1454	alcohol dehydrogenase
EN73_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
EN73_RS00445	COG1064	alcohol dehydrogenase
EN73_RS00455	COG0534	Mate efflux family protein
EN73_RS00565	COG0201	protein transport
EN73_RS00570	COG0563	adenylate kinase activity
EN73_RS00585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EN73_RS00595	COG0202	RNA polymerase activity
EN73_RS00720	COG1705	Flagellar rod assembly protein muramidase FlgJ
EN73_RS00725	COG1420	regulation of RNA biosynthetic process
EN73_RS00735	COG0443	Heat shock 70 kDa protein
EN73_RS00740	COG0484	heat shock protein binding
EN73_RS00745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EN73_RS00750	COG0101	tRNA pseudouridine synthase activity
EN73_RS00755	COG0351	phosphomethylpyrimidine kinase
EN73_RS00760	COG4720	Psort location CytoplasmicMembrane, score
EN73_RS00770	COG0668	transmembrane transport
EN73_RS00775	COG0544	peptidyl-prolyl cis-trans isomerase activity
EN73_RS00800	COG0756	dUTP diphosphatase activity
EN73_RS00815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EN73_RS00820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EN73_RS00825	COG1879	ABC-type sugar transport system periplasmic component
EN73_RS00830	COG1172	Belongs to the binding-protein-dependent transport system permease family
EN73_RS00835	COG1129	ABC transporter
EN73_RS00840	COG1869	D-ribose catabolic process
EN73_RS00845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EN73_RS00850	COG1609	Transcriptional regulator
EN73_RS00855	COG0577	efflux transmembrane transporter activity
EN73_RS00860	COG1136	(ABC) transporter
EN73_RS00865	COG0745	RESPONSE REGULATOR receiver
EN73_RS00870	COG2205	protein histidine kinase activity
EN73_RS00875	COG0137	argininosuccinate synthase activity
EN73_RS00880	COG0165	Argininosuccinate lyase
EN73_RS00885	COG0191	fructose-bisphosphate aldolase activity
EN73_RS00905	COG1461	Dihydroxyacetone kinase
EN73_RS00920	COG1126	abc transporter atp-binding protein
EN73_RS00925	COG0765	amino acid transport
EN73_RS00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EN73_RS00955	COG0719	Fe-S assembly protein
EN73_RS00960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EN73_RS00970	COG0719	Fe-S assembly protein
EN73_RS00975	COG1686	Belongs to the peptidase S11 family
EN73_RS00980	COG1686	Belongs to the peptidase S11 family
EN73_RS00985	COG4166	transmembrane transport
EN73_RS00990	COG0601	transmembrane transport
EN73_RS00995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EN73_RS01000	COG0444	Belongs to the ABC transporter superfamily
EN73_RS01005	COG4608	Belongs to the ABC transporter superfamily
EN73_RS01035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EN73_RS01045	COG1121	(ABC) transporter
EN73_RS01050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EN73_RS01060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EN73_RS01065	COG4499	WXG100 protein secretion system (Wss), protein YukC
EN73_RS01065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EN73_RS01085	COG1459	type II secretion system
EN73_RS01115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EN73_RS01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EN73_RS01140	COG1363	Peptidase, m42
EN73_RS01155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EN73_RS01160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EN73_RS01170	COG0629	single-stranded DNA binding
EN73_RS01175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EN73_RS01195	COG1346	cytolysis
EN73_RS01205	COG0601	transmembrane transport
EN73_RS01210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EN73_RS01215	COG1122	ATPase activity
EN73_RS01225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EN73_RS01225	COG1263	PTS System
EN73_RS01230	COG0366	Alpha amylase catalytic
EN73_RS01235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EN73_RS01250	COG3959	Transketolase, thiamine diphosphate binding domain
EN73_RS01255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EN73_RS01260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EN73_RS01270	COG1185	polyribonucleotide nucleotidyltransferase activity
EN73_RS01280	COG1045	serine acetyltransferase
EN73_RS01290	COG0215	cysteine-tRNA ligase activity
EN73_RS01295	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EN73_RS01315	COG1476	TRANSCRIPTIONal
EN73_RS01325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EN73_RS01335	COG0582	viral genome integration into host DNA
EN73_RS01385	COG4974	Belongs to the 'phage' integrase family
EN73_RS01395	COG0732	type I restriction modification DNA specificity domain
EN73_RS01420	COG1396	sequence-specific DNA binding
EN73_RS01435	COG1732	Glycine betaine
EN73_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
EN73_RS01580	COG1695	Transcriptional regulator
EN73_RS01595	COG1755	Isoprenylcysteine carboxyl methyltransferase
EN73_RS01610	COG0751	glycine-tRNA ligase activity
EN73_RS01635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EN73_RS01640	COG0446	pyridine nucleotide-disulphide oxidoreductase
EN73_RS01660	COG1131	(ABC) transporter
EN73_RS01670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EN73_RS01670	COG2190	(PTS) system
EN73_RS01670	COG1263	PTS System
EN73_RS01675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EN73_RS01680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EN73_RS01685	COG0275	rRNA processing
EN73_RS01695	COG0768	penicillin binding
EN73_RS01705	COG0513	Belongs to the DEAD box helicase family
EN73_RS01720	COG1126	abc transporter atp-binding protein
EN73_RS01730	COG0492	ferredoxin-NADP+ reductase activity
EN73_RS01735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EN73_RS01745	COG3579	cysteine-type endopeptidase activity
EN73_RS01750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EN73_RS01770	COG0116	Belongs to the methyltransferase superfamily
EN73_RS01780	COG1854	S-ribosylhomocysteine lyase activity
EN73_RS01785	COG1418	mRNA catabolic process
EN73_RS01785	COG4372	Transposase
EN73_RS01790	COG1131	(ABC) transporter
EN73_RS01795	COG4585	Histidine kinase
EN73_RS01810	COG0194	GDP metabolic process
EN73_RS01820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EN73_RS01825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EN73_RS01830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EN73_RS01830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EN73_RS01840	COG0515	serine threonine protein kinase
EN73_RS01840	COG2815	serine threonine protein kinase
EN73_RS01850	COG4585	Histidine kinase
EN73_RS01855	COG2197	response regulator
EN73_RS01865	COG1098	S1 RNA binding domain
EN73_RS01870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EN73_RS01875	COG1349	DNA-binding transcription factor activity
EN73_RS01885	COG1447	Phosphotransferase system cellobiose-specific component IIA
EN73_RS01895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EN73_RS01900	COG1882	Formate acetyltransferase
EN73_RS01920	COG1739	Uncharacterized protein family UPF0029
EN73_RS01925	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EN73_RS01930	COG1040	competence protein
EN73_RS01965	COG0527	aspartate kinase activity
EN73_RS01970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EN73_RS01975	COG1024	Enoyl-CoA hydratase
EN73_RS01985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EN73_RS01995	COG2070	2-Nitropropane dioxygenase
EN73_RS02000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EN73_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
EN73_RS02010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EN73_RS02025	COG0439	Biotin carboxylase
EN73_RS02045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EN73_RS02060	COG3716	PTS system mannose fructose sorbose family IID component
EN73_RS02065	COG3715	PTS system
EN73_RS02075	COG0561	phosphatase activity
EN73_RS02090	COG2252	PERMEase
EN73_RS02095	COG0802	atpase or kinase
EN73_RS02105	COG1316	TRANSCRIPTIONal
EN73_RS02115	COG0537	adenosine 5'-monophosphoramidase activity
EN73_RS02125	COG1131	(ABC) transporter
EN73_RS02130	COG4473	ABC transporter
EN73_RS02140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EN73_RS02155	COG0195	Participates in both transcription termination and antitermination
EN73_RS02160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EN73_RS02170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EN73_RS02175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EN73_RS02200	COG2860	membrane
EN73_RS02210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EN73_RS02210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EN73_RS02215	COG1832	CoA-binding protein
EN73_RS02235	COG5002	protein histidine kinase activity
EN73_RS02255	COG1268	BioY protein
EN73_RS02260	COG1234	tRNA 3'-trailer cleavage
EN73_RS02275	COG0166	Belongs to the GPI family
EN73_RS02280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EN73_RS02285	COG0705	Rhomboid family
EN73_RS02285	COG0457	Tetratricopeptide repeat
EN73_RS02290	COG1744	ABC transporter substrate-binding protein PnrA-like
EN73_RS02295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EN73_RS02310	COG0706	membrane insertase activity
EN73_RS02380	COG2137	regulation of response to DNA damage stimulus
EN73_RS02385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EN73_RS02395	COG2153	protein acetylation
EN73_RS02405	COG1216	Glycosyl transferase, family 2
EN73_RS02405	COG1442	glycosyl transferase family 8
EN73_RS02440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EN73_RS02450	COG0789	Transcriptional regulator
EN73_RS02505	COG2226	methyltransferase
EN73_RS02515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EN73_RS02520	COG3414	Phosphotransferase system galactitol-specific IIB component
EN73_RS02525	COG3775	system Galactitol-specific IIC component
EN73_RS02530	COG0235	Class ii aldolase
EN73_RS02540	COG3775	system Galactitol-specific IIC component
EN73_RS02545	COG3414	Phosphotransferase system galactitol-specific IIB component
EN73_RS02550	COG2207	Transcriptional regulator
EN73_RS02560	COG1175	transmembrane transport
EN73_RS02565	COG0395	ABC-type sugar transport system, permease component
EN73_RS02575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EN73_RS02585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EN73_RS02590	COG2017	converts alpha-aldose to the beta-anomer
EN73_RS02650	COG1518	maintenance of DNA repeat elements
EN73_RS02655	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EN73_RS02670	COG2315	Protein conserved in bacteria
EN73_RS02685	COG0742	ribosomal rna small subunit methyltransferase
EN73_RS02700	COG3480	Lon protease (S16) C-terminal proteolytic domain
EN73_RS02705	COG0737	Belongs to the 5'-nucleotidase family
EN73_RS02710	COG4470	Protein conserved in bacteria
EN73_RS02725	COG1132	(ABC) transporter
EN73_RS02730	COG1132	(ABC) transporter
EN73_RS02735	COG0512	Glutamine amidotransferase of anthranilate synthase
EN73_RS02740	COG1268	BioY protein
EN73_RS02745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EN73_RS02765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EN73_RS02780	COG1940	carbohydrate kinase activity
EN73_RS02785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EN73_RS02790	COG1217	gtp-binding protein TYPA
EN73_RS02800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EN73_RS02825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EN73_RS02835	COG0762	integral membrane protein
EN73_RS02840	COG2302	S4 RNA-binding domain
EN73_RS02845	COG3599	regulation of cell shape
EN73_RS02860	COG0494	nUDIX hydrolase
EN73_RS02865	COG0542	response to heat
EN73_RS02870	COG4703	Protein of unknown function (DUF1797)
EN73_RS02875	COG0765	amino acid transport
EN73_RS02880	COG1126	abc transporter atp-binding protein
EN73_RS02885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EN73_RS02895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EN73_RS02900	COG1570	exodeoxyribonuclease VII activity
EN73_RS02905	COG1722	exodeoxyribonuclease VII activity
EN73_RS02915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EN73_RS02920	COG1438	arginine binding
EN73_RS02925	COG0497	DNA recombination
EN73_RS02930	COG1307	EDD domain protein, DegV family
EN73_RS02935	COG2755	lipolytic protein G-D-S-L family
EN73_RS02980	COG1078	dGTPase activity
EN73_RS03005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EN73_RS03015	COG2884	Cell division ATP-binding protein ftsE
EN73_RS03020	COG2177	Part of the ABC transporter FtsEX involved in
EN73_RS03040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EN73_RS03040	COG1199	ATP-dependent helicase activity
EN73_RS03045	COG0436	Aminotransferase
EN73_RS03050	COG0017	Asparaginyl-tRNA synthetase
EN73_RS03070	COG1660	Displays ATPase and GTPase activities
EN73_RS03095	COG0254	rRNA binding
EN73_RS03100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EN73_RS03105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EN73_RS03110	COG0716	FMN binding
EN73_RS03115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EN73_RS03115	COG1605	Chorismate mutase
EN73_RS03120	COG0038	chloride channel
EN73_RS03125	COG0335	large ribosomal subunit rRNA binding
EN73_RS03135	COG0582	viral genome integration into host DNA
EN73_RS03485	COG1136	(ABC) transporter
EN73_RS03500	COG5002	protein histidine kinase activity
EN73_RS03515	COG0772	Belongs to the SEDS family
EN73_RS03535	COG0560	Phosphoserine phosphatase
EN73_RS03550	COG0148	phosphopyruvate hydratase activity
EN73_RS03570	COG1316	TRANSCRIPTIONal
EN73_RS03595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EN73_RS03600	COG4555	ABC transporter
EN73_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
EN73_RS03630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EN73_RS03635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EN73_RS03655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EN73_RS03660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EN73_RS03680	COG3064	Membrane
EN73_RS03680	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EN73_RS03695	COG3590	peptidase
EN73_RS03700	COG3590	peptidase
EN73_RS03745	COG1136	(ABC) transporter
EN73_RS03760	COG0586	Pfam SNARE associated Golgi protein
EN73_RS03765	COG4619	ABC transporter
EN73_RS03770	COG0390	transport system, permease component
EN73_RS03780	COG0583	DNA-binding transcription factor activity
EN73_RS03795	COG2211	Major facilitator Superfamily
EN73_RS03805	COG3250	beta-galactosidase activity
EN73_RS03810	COG2186	Transcriptional regulator
EN73_RS03815	COG0800	Aldolase
EN73_RS03850	COG1609	Transcriptional regulator
EN73_RS03865	COG0438	transferase activity, transferring glycosyl groups
EN73_RS03890	COG0765	amino acid transport
EN73_RS03895	COG0765	amino acid transport
EN73_RS03900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EN73_RS03905	COG1126	abc transporter atp-binding protein
EN73_RS03910	COG0745	RESPONSE REGULATOR receiver
EN73_RS03915	COG5002	protein histidine kinase activity
EN73_RS03920	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EN73_RS03925	COG2832	Protein of unknown function (DUF454)
EN73_RS03935	COG1196	nuclear chromosome segregation
EN73_RS03940	COG0561	phosphatase activity
EN73_RS03945	COG0561	phosphatase activity
EN73_RS03950	COG0552	protein localization to endoplasmic reticulum
EN73_RS03955	COG3344	reverse transcriptase
EN73_RS03960	COG3689	TIGRFAM TIGR03943 family protein
EN73_RS03965	COG0701	Predicted permease
EN73_RS03980	COG2183	response to ionizing radiation
EN73_RS03985	COG3091	SprT-like family
EN73_RS03990	COG1983	PspC domain protein
EN73_RS04025	COG0826	peptidase U32
EN73_RS04030	COG4443	Transcriptional Coactivator p15 (PC4)
EN73_RS04040	COG1914	H( )-stimulated, divalent metal cation uptake system
EN73_RS04080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EN73_RS04105	COG1164	Oligoendopeptidase f
EN73_RS04115	COG0772	Belongs to the SEDS family
EN73_RS04135	COG0768	penicillin binding
EN73_RS04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EN73_RS04155	COG2223	nitrite transmembrane transporter activity
EN73_RS04180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EN73_RS04185	COG2011	ABC-type metal ion transport system permease component
EN73_RS04190	COG1464	Belongs to the NlpA lipoprotein family
EN73_RS04195	COG0513	Belongs to the DEAD box helicase family
EN73_RS04205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EN73_RS04210	COG0204	Acyl-transferase
EN73_RS04215	COG1555	photosystem II stabilization
EN73_RS04215	COG1596	polysaccharide export
EN73_RS04220	COG0658	competence protein
EN73_RS04220	COG2333	competence protein COMEC
EN73_RS04225	COG0561	phosphatase activity
EN73_RS04230	COG1609	Transcriptional regulator
EN73_RS04235	COG0657	acetylesterase activity
EN73_RS04240	COG2226	methyltransferase
EN73_RS04250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EN73_RS04255	COG3711	transcriptional antiterminator
EN73_RS04270	COG3835	regulator
EN73_RS04275	COG1929	Belongs to the glycerate kinase type-1 family
EN73_RS04280	COG2610	gluconate transmembrane transporter activity
EN73_RS04290	COG1846	Transcriptional regulator
EN73_RS04295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EN73_RS04305	COG0363	glucosamine-6-phosphate deaminase activity
EN73_RS04310	COG0435	Glutathione S-transferase
EN73_RS04315	COG1187	pseudouridine synthase activity
EN73_RS04335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EN73_RS04340	COG4122	O-methyltransferase activity
EN73_RS04345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EN73_RS04350	COG4894	glucomannan catabolic process
EN73_RS04355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EN73_RS04360	COG1811	Na channel or pump
EN73_RS04365	COG1442	glycosyl transferase family 8
EN73_RS04380	COG1476	TRANSCRIPTIONal
EN73_RS04395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EN73_RS04400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EN73_RS04405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EN73_RS04420	COG1012	belongs to the aldehyde dehydrogenase family
EN73_RS04425	COG0726	polysaccharide deacetylase
EN73_RS04430	COG0513	Belongs to the DEAD box helicase family
EN73_RS04440	COG1956	GAF domain-containing protein
EN73_RS04445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EN73_RS04455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EN73_RS04455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EN73_RS04485	COG4721	ABC-type cobalt transport system, permease component
EN73_RS04490	COG1122	ATPase activity
EN73_RS04500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EN73_RS04520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EN73_RS04530	COG4109	DRTGG domain
EN73_RS04535	COG0024	Methionine aminopeptidase
EN73_RS04545	COG2246	polysaccharide biosynthetic process
EN73_RS04550	COG4708	membrane
EN73_RS04555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EN73_RS04560	COG1597	lipid kinase activity
EN73_RS04565	COG1523	belongs to the glycosyl hydrolase 13 family
EN73_RS04625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EN73_RS04635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EN73_RS04660	COG0072	phenylalanine-tRNA ligase activity
EN73_RS04660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EN73_RS04665	COG2321	neutral zinc metallopeptidase
EN73_RS04670	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EN73_RS04675	COG1074	ATP-dependent DNA helicase activity
EN73_RS04685	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EN73_RS04690	COG0488	(ABC) transporter
EN73_RS04695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EN73_RS04700	COG0022	dehydrogenase e1 component
EN73_RS04700	COG0508	dehydrogenase complex catalyzes the overall conversion of
EN73_RS04705	COG0508	dehydrogenase complex catalyzes the overall conversion of
EN73_RS04715	COG0095	Lipoate-protein ligase
EN73_RS04720	COG3344	reverse transcriptase
EN73_RS04725	COG3442	glutamine amidotransferase
EN73_RS04730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EN73_RS04735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EN73_RS04760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EN73_RS04770	COG0647	UMP catabolic process
EN73_RS04780	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EN73_RS04790	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EN73_RS04810	COG0481	GTPase activity
EN73_RS04820	COG1418	mRNA catabolic process
EN73_RS04825	COG0456	acetyltransferase
EN73_RS04835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EN73_RS04860	COG1131	(ABC) transporter
EN73_RS04865	COG1725	Transcriptional regulator
EN73_RS04875	COG0205	6-phosphofructokinase activity
EN73_RS04880	COG0469	pyruvate kinase activity
EN73_RS04890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EN73_RS04895	COG2824	Alkylphosphonate utilization operon protein PhnA
EN73_RS04900	COG0765	amino acid transport
EN73_RS04905	COG1126	abc transporter atp-binding protein
EN73_RS04920	COG1072	(Pantothenic acid kinase))
EN73_RS04925	COG2813	Specifically methylates the guanine in position
EN73_RS04935	COG1744	ABC transporter substrate-binding protein PnrA-like
EN73_RS04940	COG3845	ABC transporter
EN73_RS04945	COG4603	Belongs to the binding-protein-dependent transport system permease family
EN73_RS04950	COG1079	Belongs to the binding-protein-dependent transport system permease family
EN73_RS04970	COG3764	Sortase (surface protein transpeptidase)
EN73_RS04975	COG0346	lactoylglutathione lyase activity
EN73_RS04995	COG2188	Transcriptional regulator
EN73_RS05010	COG1464	Belongs to the NlpA lipoprotein family
EN73_RS05025	COG1136	(ABC) transporter
EN73_RS05035	COG0745	RESPONSE REGULATOR receiver
EN73_RS05040	COG5002	protein histidine kinase activity
EN73_RS05045	COG4974	Belongs to the 'phage' integrase family
EN73_RS05050	COG4166	transmembrane transport
EN73_RS05065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EN73_RS05070	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EN73_RS05075	COG5002	protein histidine kinase activity
EN73_RS05080	COG0745	RESPONSE REGULATOR receiver
EN73_RS05090	COG0704	Plays a role in the regulation of phosphate uptake
EN73_RS05095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EN73_RS05100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EN73_RS05105	COG0581	inorganic phosphate transmembrane transporter activity
EN73_RS05110	COG0573	inorganic phosphate transmembrane transporter activity
EN73_RS05120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EN73_RS05120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EN73_RS05125	COG0483	inositol monophosphate 1-phosphatase activity
EN73_RS05130	COG4476	Belongs to the UPF0223 family
EN73_RS05140	COG0196	riboflavin kinase activity
EN73_RS05145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EN73_RS05175	COG1136	(ABC) transporter
EN73_RS05180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EN73_RS05185	COG0758	DNA mediated transformation
EN73_RS05190	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EN73_RS05195	COG4604	ABC transporter, ATP-binding protein
EN73_RS05200	COG4605	iron ion homeostasis
EN73_RS05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EN73_RS05210	COG0110	maltose O-acetyltransferase activity
EN73_RS05220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EN73_RS05225	COG1376	ErfK ybiS ycfS ynhG family protein
EN73_RS05230	COG1966	Carbon starvation protein
EN73_RS05235	COG3279	Response regulator of the LytR AlgR family
EN73_RS05240	COG3275	phosphorelay sensor kinase activity
EN73_RS05290	COG0505	Belongs to the CarA family
EN73_RS05305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EN73_RS05320	COG0488	(ABC) transporter
EN73_RS05330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EN73_RS05340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EN73_RS05380	COG0095	Lipoate-protein ligase
EN73_RS05390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EN73_RS05395	COG4684	Psort location CytoplasmicMembrane, score
EN73_RS05400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EN73_RS05410	COG1132	(ABC) transporter
EN73_RS05440	COG2890	protein-(glutamine-N5) methyltransferase activity
EN73_RS05445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EN73_RS05455	COG1942	4-Oxalocrotonate Tautomerase
EN73_RS05470	COG1053	succinate dehydrogenase
EN73_RS05470	COG0431	NADPH-dependent FMN reductase
EN73_RS05470	COG3976	FMN-binding domain protein
EN73_RS05480	COG2233	PERMEase
EN73_RS05495	COG0477	Major facilitator Superfamily
EN73_RS05510	COG4221	oxidoreductase activity
EN73_RS05515	COG4221	oxidoreductase activity
EN73_RS05520	COG0280	phosphate acetyltransferase
EN73_RS05525	COG0564	pseudouridine synthase activity
EN73_RS05535	COG2357	RelA SpoT domain protein
EN73_RS05550	COG1104	cysteine desulfurase activity
EN73_RS05560	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EN73_RS05565	COG2003	Belongs to the UPF0758 family
EN73_RS05570	COG0628	permease
EN73_RS05575	COG2723	6-phospho-beta-galactosidase activity
EN73_RS05585	COG0561	phosphatase activity
EN73_RS05595	COG0038	chloride channel
EN73_RS05605	COG1177	transmembrane transport
EN73_RS05610	COG1176	ABC-type spermidine putrescine transport system, permease component I
EN73_RS05620	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EN73_RS05625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EN73_RS05645	COG0285	dihydrofolate synthase activity
EN73_RS05650	COG2962	Rard protein
EN73_RS05665	COG0726	polysaccharide deacetylase
EN73_RS05675	COG1012	belongs to the aldehyde dehydrogenase family
EN73_RS05750	COG2261	transglycosylase associated protein
EN73_RS05775	COG1115	amino acid carrier protein
EN73_RS05780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EN73_RS05790	COG1346	cytolysis
EN73_RS05805	COG0539	negative regulation of cytoplasmic translation
EN73_RS05825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EN73_RS05835	COG0187	DNA topoisomerase II activity
EN73_RS05840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EN73_RS05845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EN73_RS05855	COG2755	lipolytic protein G-D-S-L family
EN73_RS05855	COG1083	cytidylyl-transferase
EN73_RS05870	COG2089	acid synthase
EN73_RS05885	COG1442	glycosyl transferase family 8
EN73_RS05885	COG1216	Glycosyl transferase, family 2
EN73_RS05895	COG1215	transferase activity, transferring glycosyl groups
EN73_RS05910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EN73_RS05915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EN73_RS05935	COG1316	TRANSCRIPTIONal
EN73_RS05960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EN73_RS05995	COG3842	ATPase activity
EN73_RS06010	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EN73_RS06015	COG3527	Alpha-acetolactate decarboxylase
EN73_RS06020	COG0028	Belongs to the TPP enzyme family
EN73_RS06025	COG0457	Tetratricopeptide repeat
EN73_RS06030	COG0628	permease
EN73_RS06040	COG1051	belongs to the nudix hydrolase family
EN73_RS06045	COG5492	domain, Protein
EN73_RS06050	COG1088	dTDP-glucose 4,6-dehydratase activity
EN73_RS06060	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EN73_RS06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EN73_RS06075	COG2384	SAM-dependent methyltransferase
EN73_RS06095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EN73_RS06095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EN73_RS06100	COG0300	oxidoreductase activity
EN73_RS06115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EN73_RS06120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EN73_RS06145	COG1573	uracil-dna glycosylase
EN73_RS06150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EN73_RS06160	COG0584	glycerophosphoryl diester phosphodiesterase
EN73_RS06165	COG2801	Transposase and inactivated derivatives
EN73_RS06185	COG0534	Mate efflux family protein
EN73_RS06220	COG2801	Transposase and inactivated derivatives
EN73_RS06230	COG0803	Belongs to the bacterial solute-binding protein 9 family
EN73_RS06235	COG3344	reverse transcriptase
EN73_RS06300	COG2040	homocysteine
EN73_RS06305	COG0833	amino acid
EN73_RS06340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EN73_RS06350	COG3425	synthase
EN73_RS06365	COG1272	protein, Hemolysin III
EN73_RS06410	COG0745	RESPONSE REGULATOR receiver
EN73_RS06415	COG2357	RelA SpoT domain protein
EN73_RS06435	COG0737	Belongs to the 5'-nucleotidase family
EN73_RS06440	COG0242	peptide deformylase activity
EN73_RS06445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EN73_RS06455	COG1132	(ABC) transporter
EN73_RS06470	COG0488	(ABC) transporter
EN73_RS06500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EN73_RS06500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EN73_RS06500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EN73_RS06505	COG1105	Belongs to the carbohydrate kinase PfkB family
EN73_RS06510	COG1349	DNA-binding transcription factor activity
EN73_RS06565	COG1837	Belongs to the UPF0109 family
EN73_RS06570	COG0228	four-way junction DNA binding
EN73_RS06575	COG0577	efflux transmembrane transporter activity
EN73_RS06580	COG1136	(ABC) transporter
EN73_RS06585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EN73_RS06590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EN73_RS06595	COG0505	Belongs to the CarA family
EN73_RS06605	COG0564	pseudouridine synthase activity
EN73_RS06615	COG0583	DNA-binding transcription factor activity
EN73_RS06620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EN73_RS06645	COG1104	cysteine desulfurase activity
EN73_RS06655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EN73_RS06660	COG1442	glycosyl transferase family 8
EN73_RS06680	COG0653	protein targeting
EN73_RS06690	COG1073	alpha beta
EN73_RS06735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EN73_RS06740	COG1368	sulfuric ester hydrolase activity
EN73_RS06745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EN73_RS06755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EN73_RS06785	COG2244	polysaccharide biosynthetic process
EN73_RS06790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EN73_RS06795	COG1120	ATPase activity
EN73_RS06800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EN73_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EN73_RS06810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EN73_RS06825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EN73_RS06830	COG1253	flavin adenine dinucleotide binding
EN73_RS06840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EN73_RS06845	COG1242	4 iron, 4 sulfur cluster binding
EN73_RS06850	COG0671	phosphoesterase, PA-phosphatase related
EN73_RS06855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EN73_RS06885	COG0681	Belongs to the peptidase S26 family
EN73_RS06895	COG0297	glycogen (starch) synthase activity
EN73_RS06935	COG3475	LICD family
EN73_RS06950	COG0463	Glycosyl transferase, family 2
EN73_RS06955	COG1215	transferase activity, transferring glycosyl groups
EN73_RS06965	COG1091	dTDP-4-dehydrorhamnose reductase activity
EN73_RS06970	COG2151	metal-sulfur cluster biosynthetic enzyme
EN73_RS06975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EN73_RS06980	COG0358	DNA primase activity
EN73_RS06985	COG1970	mechanosensitive ion channel activity
EN73_RS06990	COG2801	Transposase and inactivated derivatives
EN73_RS07010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EN73_RS07015	COG0004	ammonium transporteR
EN73_RS07025	COG1054	Belongs to the UPF0176 family
EN73_RS07035	COG2271	Major facilitator Superfamily
EN73_RS07040	COG0058	SHG alpha-glucan phosphorylase activity
EN73_RS07045	COG1640	4-alpha-glucanotransferase
EN73_RS07050	COG1609	Transcriptional regulator
EN73_RS07060	COG1175	transmembrane transport
EN73_RS07065	COG3833	ABC-type maltose transport systems, permease component
EN73_RS07070	COG3104	oligopeptide transport
EN73_RS07075	COG2801	Transposase and inactivated derivatives
EN73_RS07105	COG0765	amino acid transport
EN73_RS07110	COG1126	abc transporter atp-binding protein
EN73_RS07135	COG2309	aminopeptidase activity
EN73_RS07155	COG1187	pseudouridine synthase activity
EN73_RS07160	COG0656	L-ascorbic acid biosynthetic process
EN73_RS07165	COG0778	Nitroreductase
EN73_RS07170	COG0346	lactoylglutathione lyase activity
EN73_RS07175	COG0463	Glycosyl transferase, family 2
EN73_RS07180	COG1113	amino acid transport
EN73_RS07185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EN73_RS07190	COG0557	exoribonuclease II activity
EN73_RS07200	COG2814	Major facilitator Superfamily
EN73_RS07210	COG1131	(ABC) transporter
EN73_RS07220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EN73_RS07225	COG1396	sequence-specific DNA binding
EN73_RS07260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EN73_RS07265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EN73_RS07285	COG1702	phosphate starvation-inducible protein PhoH
EN73_RS07310	COG0233	cytoplasmic translational termination
EN73_RS07325	COG0444	Belongs to the ABC transporter superfamily
EN73_RS07330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EN73_RS07335	COG0601	transmembrane transport
EN73_RS07340	COG0747	negative chemotaxis
EN73_RS07345	COG0081	regulation of translation
EN73_RS07365	COG1473	amidohydrolase
EN73_RS07370	COG0583	DNA-binding transcription factor activity
EN73_RS07385	COG2801	Transposase and inactivated derivatives
EN73_RS07390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EN73_RS07395	COG1674	ftsk spoiiie
EN73_RS07400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EN73_RS07425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EN73_RS07455	COG0673	inositol 2-dehydrogenase activity
EN73_RS07470	COG1028	Short-chain dehydrogenase reductase Sdr
EN73_RS07520	COG1114	Component of the transport system for branched-chain amino acids
EN73_RS07525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EN73_RS07525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EN73_RS07540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EN73_RS07550	COG0708	Exodeoxyribonuclease III
EN73_RS07555	COG1393	Belongs to the ArsC family
EN73_RS07560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EN73_RS07565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EN73_RS07575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EN73_RS07595	COG0470	DNA polymerase III
EN73_RS07605	COG0517	IMP dehydrogenase activity
EN73_RS07645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EN73_RS07650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EN73_RS07660	COG0531	amino acid
EN73_RS07665	COG0569	domain protein
EN73_RS07680	COG1187	pseudouridine synthase activity
EN73_RS07690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EN73_RS07695	COG0582	viral genome integration into host DNA
EN73_RS07715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EN73_RS07730	COG1827	regulation of RNA biosynthetic process
EN73_RS07745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EN73_RS07750	COG1254	Belongs to the acylphosphatase family
EN73_RS07755	COG0706	membrane insertase activity
EN73_RS07760	COG0765	amino acid transport
EN73_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EN73_RS07780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EN73_RS07790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EN73_RS07810	COG1484	DNA-dependent DNA replication
EN73_RS07825	COG5002	protein histidine kinase activity
EN73_RS07830	COG0745	RESPONSE REGULATOR receiver
EN73_RS07840	COG0501	Belongs to the peptidase M48B family
EN73_RS07845	COG1704	LemA family
EN73_RS07850	COG0357	Ribosomal RNA small subunit methyltransferase G
EN73_RS07855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EN73_RS07860	COG0569	domain protein
EN73_RS07870	COG1122	ATPase activity
EN73_RS07880	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EN73_RS07885	COG1114	Component of the transport system for branched-chain amino acids
EN73_RS07890	COG1063	alcohol dehydrogenase
EN73_RS07915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EN73_RS07920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EN73_RS07925	COG0217	transcriptional regulatory protein
EN73_RS07930	COG2376	Dihydroxyacetone kinase
EN73_RS07935	COG1309	transcriptional regulator
EN73_RS07940	COG2376	Dihydroxyacetone kinase
EN73_RS07945	COG1461	Dihydroxyacetone kinase
EN73_RS07950	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EN73_RS07955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EN73_RS07965	COG0789	Transcriptional regulator
EN73_RS07970	COG1323	Belongs to the UPF0348 family
EN73_RS07980	COG2226	methyltransferase
EN73_RS07985	COG0799	negative regulation of ribosome biogenesis
EN73_RS07995	COG1713	HD superfamily hydrolase involved in NAD metabolism
EN73_RS08000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EN73_RS08005	COG1534	Rna-binding protein
EN73_RS08010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EN73_RS08015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EN73_RS08025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EN73_RS08030	COG0154	amidase activity
EN73_RS08035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EN73_RS08040	COG0574	Belongs to the PEP-utilizing enzyme family
EN73_RS08040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EN73_RS08045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EN73_RS08050	COG0517	IMP dehydrogenase activity
EN73_RS08060	COG1335	isochorismatase
EN73_RS08065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EN73_RS08070	COG0436	Aminotransferase
EN73_RS08075	COG0589	response to stress
EN73_RS08080	COG0561	phosphatase activity
EN73_RS08085	COG0252	asparaginase activity
EN73_RS08095	COG4989	oxidoreductase activity
EN73_RS08100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EN73_RS08105	COG3942	CHAP domain
EN73_RS08105	COG1705	Flagellar rod assembly protein muramidase FlgJ
EN73_RS08115	COG0736	holo-[acyl-carrier-protein] synthase activity
EN73_RS08120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EN73_RS08130	COG1482	cell wall glycoprotein biosynthetic process
EN73_RS08135	COG1940	carbohydrate kinase activity
EN73_RS08140	COG1263	PTS System
EN73_RS08140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EN73_RS08140	COG2190	(PTS) system
EN73_RS08145	COG1621	beta-fructofuranosidase activity
EN73_RS08150	COG1609	Transcriptional regulator
EN73_RS08155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EN73_RS08165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EN73_RS08170	COG1132	(ABC) transporter
EN73_RS08180	COG1129	ABC transporter
EN73_RS08205	COG1021	2,3-dihydroxybenzoate-AMP ligase
EN73_RS08215	COG2131	deaminase
EN73_RS08220	COG0006	proline dipeptidase activity
EN73_RS08230	COG2814	Major facilitator Superfamily
EN73_RS08255	COG0629	single-stranded DNA binding
EN73_RS08260	COG0360	Binds together with S18 to 16S ribosomal RNA
EN73_RS08265	COG1194	a g-specific adenine glycosylase
EN73_RS08275	COG3118	belongs to the thioredoxin family
EN73_RS08285	COG1193	negative regulation of DNA recombination
EN73_RS08300	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EN73_RS08305	COG0681	Belongs to the peptidase S26 family
EN73_RS08310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EN73_RS08325	COG1882	Formate acetyltransferase
EN73_RS08330	COG3576	pyridoxamine 5-phosphate
EN73_RS08335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EN73_RS08350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EN73_RS08360	COG2814	Major facilitator Superfamily
EN73_RS08365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EN73_RS08370	COG2936	dipeptidyl-peptidase activity
EN73_RS08380	COG0142	geranyltranstransferase activity
EN73_RS08385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EN73_RS08390	COG4988	ABC transporter
EN73_RS08395	COG1294	oxidase, subunit
EN73_RS08400	COG1271	oxidase subunit
EN73_RS08405	COG1252	NADH dehydrogenase
EN73_RS08420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EN73_RS08425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EN73_RS08430	COG0789	Transcriptional regulator
EN73_RS08445	COG2081	HI0933 family
EN73_RS08465	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EN73_RS08470	COG0456	acetyltransferase
EN73_RS08475	COG1214	PFAM Peptidase M22, glycoprotease
EN73_RS08490	COG3942	CHAP domain
EN73_RS08495	COG0174	glutamine synthetase
EN73_RS08500	COG0789	Transcriptional regulator
EN73_RS08510	COG0126	phosphoglycerate kinase activity
EN73_RS08515	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EN73_RS08525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EN73_RS08540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EN73_RS08565	COG1162	GTPase activity
EN73_RS08575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EN73_RS08590	COG0084	hydrolase, TatD family'
EN73_RS08615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EN73_RS08620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EN73_RS08625	COG1696	Membrane protein involved in D-alanine export
EN73_RS08640	COG5002	protein histidine kinase activity
EN73_RS08645	COG0745	RESPONSE REGULATOR receiver
EN73_RS08655	COG3314	Sporulation integral membrane protein YlbJ
EN73_RS08665	COG3448	diguanylate cyclase activity
EN73_RS08665	COG4175	Glycine betaine
EN73_RS08670	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EN73_RS08690	COG1070	Carbohydrate kinase
EN73_RS08700	COG3775	system Galactitol-specific IIC component
EN73_RS08705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EN73_RS08715	COG1609	Transcriptional regulator
EN73_RS08765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EN73_RS08795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EN73_RS08800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EN73_RS08805	COG1428	Deoxynucleoside kinase
EN73_RS08815	COG0542	response to heat
EN73_RS08820	COG4463	regulation of RNA biosynthetic process
EN73_RS08840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EN73_RS08850	COG0450	alkyl hydroperoxide reductase
EN73_RS08865	COG0025	NhaP-type Na H and K H
EN73_RS08875	COG1619	proteins homologs of microcin C7 resistance protein MccF
EN73_RS08880	COG3590	peptidase
EN73_RS08905	COG1609	Transcriptional regulator
EN73_RS08915	COG3716	PTS system mannose fructose sorbose family IID component
EN73_RS08920	COG3715	PTS system
EN73_RS08925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EN73_RS08930	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EN73_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
EN73_RS08975	COG2176	DNA-directed DNA polymerase activity
EN73_RS08980	COG1388	LysM domain
EN73_RS08980	COG1705	Flagellar rod assembly protein muramidase FlgJ
EN73_RS08995	COG4589	Belongs to the CDS family
EN73_RS09000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EN73_RS09005	COG1862	Preprotein translocase
EN73_RS09020	COG3493	citrate carrier protein
EN73_RS09025	COG3290	protein histidine kinase activity
EN73_RS09030	COG4565	transcriptional regulatory protein
EN73_RS09035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EN73_RS09045	COG3842	ATPase activity
EN73_RS09120	COG1490	D-aminoacyl-tRNA deacylase activity
EN73_RS09130	COG0737	Belongs to the 5'-nucleotidase family
EN73_RS09140	COG1363	Peptidase, m42
EN73_RS09160	COG2207	Transcriptional regulator
EN73_RS09160	COG4753	response regulator
EN73_RS09165	COG2972	Histidine kinase
EN73_RS09170	COG3716	PTS system mannose fructose sorbose family IID component
EN73_RS09175	COG3715	PTS system
EN73_RS09205	COG1131	(ABC) transporter
EN73_RS09215	COG3279	Response regulator of the LytR AlgR family
EN73_RS09225	COG1263	PTS System
EN73_RS09225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EN73_RS09225	COG2190	(PTS) system
EN73_RS09230	COG5002	protein histidine kinase activity
EN73_RS09235	COG0745	RESPONSE REGULATOR receiver
EN73_RS09245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EN73_RS09250	COG0581	inorganic phosphate transmembrane transporter activity
EN73_RS09255	COG0573	inorganic phosphate transmembrane transporter activity
EN73_RS09270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EN73_RS09285	COG0789	Transcriptional regulator
EN73_RS09305	COG0456	acetyltransferase
EN73_RS09310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EN73_RS09320	COG0582	viral genome integration into host DNA
EN73_RS09380	COG0433	COG0433 Predicted ATPase
EN73_RS09400	COG4115	mRNA cleavage
EN73_RS09445	COG1674	ftsk spoiiie
EN73_RS09490	COG1396	sequence-specific DNA binding
EN73_RS09540	COG1914	H( )-stimulated, divalent metal cation uptake system
EN73_RS09550	COG1131	(ABC) transporter
EN73_RS09585	COG1131	(ABC) transporter
EN73_RS09595	COG1396	sequence-specific DNA binding
EN73_RS09605	COG1694	Mazg nucleotide pyrophosphohydrolase
EN73_RS09635	COG0371	Dehydrogenase
EN73_RS09645	COG0646	methionine synthase
EN73_RS09645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EN73_RS09650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EN73_RS09660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EN73_RS09670	COG0745	RESPONSE REGULATOR receiver
EN73_RS09675	COG2205	protein histidine kinase activity
EN73_RS09675	COG2770	Histidine kinase
EN73_RS09685	COG0495	leucyl-tRNA aminoacylation
EN73_RS09690	COG2814	Major facilitator Superfamily
EN73_RS09695	COG4667	esterase of the alpha-beta hydrolase superfamily
EN73_RS09700	COG1442	glycosyl transferase family 8
EN73_RS09705	COG1442	glycosyl transferase family 8
EN73_RS09730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EN73_RS09735	COG0564	pseudouridine synthase activity
EN73_RS09755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EN73_RS09760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EN73_RS09780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EN73_RS09785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EN73_RS09785	COG1116	anion transmembrane transporter activity
EN73_RS09790	COG4120	Belongs to the binding-protein-dependent transport system permease family
EN73_RS09800	COG0561	phosphatase activity
EN73_RS09805	COG2514	catechol 2,3-dioxygenase activity
EN73_RS09815	COG0602	queuosine metabolic process
EN73_RS09835	COG1328	CTP reductase activity
EN73_RS09855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EN73_RS09865	COG1393	Belongs to the ArsC family
EN73_RS09870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EN73_RS09875	COG1546	Belongs to the CinA family
EN73_RS09875	COG1058	Belongs to the CinA family
EN73_RS09880	COG2818	Glycosylase
EN73_RS09895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EN73_RS09925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EN73_RS09930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EN73_RS09940	COG0124	histidyl-tRNA synthetase
EN73_RS09950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EN73_RS09960	COG4974	Belongs to the 'phage' integrase family
EN73_RS09970	COG2946	Replication initiation factor
EN73_RS10000	COG3177	Filamentation induced by cAMP protein fic
EN73_RS10055	COG4974	Belongs to the 'phage' integrase family
EN73_RS10065	COG0745	RESPONSE REGULATOR receiver
EN73_RS10070	COG5002	protein histidine kinase activity
EN73_RS10075	COG1288	antiporter activity
EN73_RS10085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EN73_RS10090	COG3852	Histidine kinase
EN73_RS10095	COG0784	Response regulator, receiver
EN73_RS10100	COG0517	IMP dehydrogenase activity
EN73_RS10100	COG1125	glycine betaine transport
EN73_RS10105	COG1174	glycine betaine transport
EN73_RS10110	COG0392	lysyltransferase activity
EN73_RS10110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EN73_RS10120	COG3759	membrane
EN73_RS10150	COG0305	Participates in initiation and elongation during chromosome replication
EN73_RS10165	COG0445	tRNA wobble uridine modification
EN73_RS10170	COG2095	MarC family integral membrane protein
EN73_RS10175	COG0482	sulfurtransferase activity
EN73_RS10180	COG1760	l-serine dehydratase
EN73_RS10185	COG1760	l-serine dehydratase
EN73_RS10190	COG0741	lytic transglycosylase activity
EN73_RS10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EN73_RS10220	COG0612	Peptidase, M16
EN73_RS10225	COG0612	Peptidase, M16
EN73_RS10230	COG2501	S4 domain
EN73_RS10250	COG0516	GMP reductase activity
EN73_RS10250	COG0517	IMP dehydrogenase activity
EN73_RS10260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EN73_RS10275	COG0454	-acetyltransferase
EN73_RS10280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EN73_RS10305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EN73_RS10310	COG0488	(ABC) transporter
EN73_RS10315	COG4485	Bacterial membrane protein, YfhO
EN73_RS10335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EN73_RS10340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EN73_RS10350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB