locus-tag	class	description
SaSA184_RS00010	COG0592	DNA-directed DNA polymerase activity
SaSA184_RS00030	COG0012	GTP binding
SaSA184_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA184_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA184_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA184_RS00230	COG1695	Transcriptional regulator
SaSA184_RS00245	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA184_RS00280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA184_RS00315	COG1131	(ABC) transporter
SaSA184_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA184_RS00325	COG2190	(PTS) system
SaSA184_RS00325	COG1263	PTS System
SaSA184_RS00330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA184_RS00335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA184_RS00340	COG0275	rRNA processing
SaSA184_RS00360	COG0513	Belongs to the DEAD box helicase family
SaSA184_RS00375	COG1126	abc transporter atp-binding protein
SaSA184_RS00385	COG0492	ferredoxin-NADP+ reductase activity
SaSA184_RS00390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA184_RS00405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA184_RS00435	COG0116	Belongs to the methyltransferase superfamily
SaSA184_RS00445	COG1854	S-ribosylhomocysteine lyase activity
SaSA184_RS00450	COG1418	mRNA catabolic process
SaSA184_RS00450	COG4372	Transposase
SaSA184_RS00460	COG1131	(ABC) transporter
SaSA184_RS00485	COG0194	GDP metabolic process
SaSA184_RS00495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA184_RS00500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA184_RS00505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA184_RS00505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA184_RS00515	COG0515	serine threonine protein kinase
SaSA184_RS00515	COG2815	serine threonine protein kinase
SaSA184_RS00525	COG4585	Histidine kinase
SaSA184_RS00530	COG2197	response regulator
SaSA184_RS00540	COG1098	S1 RNA binding domain
SaSA184_RS00550	COG1349	DNA-binding transcription factor activity
SaSA184_RS00560	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA184_RS00580	COG1739	Uncharacterized protein family UPF0029
SaSA184_RS00590	COG1040	competence protein
SaSA184_RS00625	COG0527	aspartate kinase activity
SaSA184_RS00630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA184_RS00640	COG1024	Enoyl-CoA hydratase
SaSA184_RS00650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA184_RS00660	COG2070	2-Nitropropane dioxygenase
SaSA184_RS00665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA184_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA184_RS00675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA184_RS00690	COG0439	Biotin carboxylase
SaSA184_RS00710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SaSA184_RS00725	COG3716	PTS system mannose fructose sorbose family IID component
SaSA184_RS00730	COG3715	PTS system
SaSA184_RS00745	COG0561	phosphatase activity
SaSA184_RS00760	COG2252	PERMEase
SaSA184_RS00765	COG0802	atpase or kinase
SaSA184_RS00775	COG1316	TRANSCRIPTIONal
SaSA184_RS00785	COG0537	adenosine 5'-monophosphoramidase activity
SaSA184_RS00800	COG1131	(ABC) transporter
SaSA184_RS00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA184_RS00830	COG0195	Participates in both transcription termination and antitermination
SaSA184_RS00835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA184_RS00845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA184_RS00850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA184_RS00875	COG2860	membrane
SaSA184_RS00885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA184_RS00885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA184_RS00890	COG1832	CoA-binding protein
SaSA184_RS00925	COG1268	BioY protein
SaSA184_RS00930	COG1234	tRNA 3'-trailer cleavage
SaSA184_RS00945	COG0166	Belongs to the GPI family
SaSA184_RS00950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA184_RS00955	COG0457	Tetratricopeptide repeat
SaSA184_RS00955	COG0705	Rhomboid family
SaSA184_RS00960	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA184_RS00965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA184_RS00980	COG0706	membrane insertase activity
SaSA184_RS01085	COG0436	Aminotransferase
SaSA184_RS01105	COG0416	fatty acid biosynthetic process
SaSA184_RS01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA184_RS01115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA184_RS01120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA184_RS01135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA184_RS01175	COG0395	ABC-type sugar transport system, permease component
SaSA184_RS01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA184_RS01200	COG3458	cephalosporin-C deacetylase activity
SaSA184_RS01205	COG1737	Transcriptional regulator
SaSA184_RS01215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA184_RS01235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA184_RS01250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA184_RS01260	COG2755	lipolytic protein G-D-S-L family
SaSA184_RS01260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA184_RS01265	COG1454	alcohol dehydrogenase
SaSA184_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
SaSA184_RS01270	COG1064	alcohol dehydrogenase
SaSA184_RS01280	COG0534	Mate efflux family protein
SaSA184_RS01390	COG0201	protein transport
SaSA184_RS01395	COG0563	adenylate kinase activity
SaSA184_RS01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SaSA184_RS01420	COG0202	RNA polymerase activity
SaSA184_RS01465	COG1121	(ABC) transporter
SaSA184_RS01470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA184_RS01480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA184_RS01485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA184_RS01485	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA184_RS01510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA184_RS01515	COG1459	type II secretion system
SaSA184_RS01560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SaSA184_RS01565	COG1363	Peptidase, m42
SaSA184_RS01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA184_RS01585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA184_RS01600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA184_RS01620	COG1346	cytolysis
SaSA184_RS01630	COG0601	transmembrane transport
SaSA184_RS01635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA184_RS01640	COG1122	ATPase activity
SaSA184_RS01655	COG0366	Alpha amylase catalytic
SaSA184_RS01660	COG0366	Alpha amylase catalytic
SaSA184_RS01675	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA184_RS01705	COG1045	serine acetyltransferase
SaSA184_RS01715	COG0215	cysteine-tRNA ligase activity
SaSA184_RS01720	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA184_RS01745	COG1476	TRANSCRIPTIONal
SaSA184_RS01750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA184_RS01805	COG1396	sequence-specific DNA binding
SaSA184_RS01820	COG1732	Glycine betaine
SaSA184_RS01955	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA184_RS01970	COG0443	Heat shock 70 kDa protein
SaSA184_RS01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA184_RS01990	COG0351	phosphomethylpyrimidine kinase
SaSA184_RS01995	COG4720	Psort location CytoplasmicMembrane, score
SaSA184_RS02005	COG0668	transmembrane transport
SaSA184_RS02035	COG0756	dUTP diphosphatase activity
SaSA184_RS02065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA184_RS02070	COG1879	ABC-type sugar transport system periplasmic component
SaSA184_RS02075	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA184_RS02090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA184_RS02105	COG0577	efflux transmembrane transporter activity
SaSA184_RS02110	COG1136	(ABC) transporter
SaSA184_RS02120	COG5002	protein histidine kinase activity
SaSA184_RS02135	COG0191	fructose-bisphosphate aldolase activity
SaSA184_RS02155	COG1461	Dihydroxyacetone kinase
SaSA184_RS02175	COG1126	abc transporter atp-binding protein
SaSA184_RS02180	COG0765	amino acid transport
SaSA184_RS02200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA184_RS02210	COG0719	Fe-S assembly protein
SaSA184_RS02225	COG0719	Fe-S assembly protein
SaSA184_RS02230	COG1686	Belongs to the peptidase S11 family
SaSA184_RS02235	COG1686	Belongs to the peptidase S11 family
SaSA184_RS02240	COG4166	transmembrane transport
SaSA184_RS02245	COG0601	transmembrane transport
SaSA184_RS02250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA184_RS02255	COG0444	Belongs to the ABC transporter superfamily
SaSA184_RS02260	COG4608	Belongs to the ABC transporter superfamily
SaSA184_RS02315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA184_RS02325	COG2153	protein acetylation
SaSA184_RS02335	COG1216	Glycosyl transferase, family 2
SaSA184_RS02335	COG1442	glycosyl transferase family 8
SaSA184_RS02395	COG0789	Transcriptional regulator
SaSA184_RS02400	COG1063	alcohol dehydrogenase
SaSA184_RS02405	COG0656	L-ascorbic acid biosynthetic process
SaSA184_RS02445	COG2226	methyltransferase
SaSA184_RS02455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA184_RS02460	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA184_RS02465	COG3775	system Galactitol-specific IIC component
SaSA184_RS02470	COG0235	Class ii aldolase
SaSA184_RS02485	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA184_RS02490	COG2207	Transcriptional regulator
SaSA184_RS02500	COG1175	transmembrane transport
SaSA184_RS02505	COG0395	ABC-type sugar transport system, permease component
SaSA184_RS02525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA184_RS02595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA184_RS02610	COG2315	Protein conserved in bacteria
SaSA184_RS02625	COG0742	ribosomal rna small subunit methyltransferase
SaSA184_RS02640	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA184_RS02650	COG4470	Protein conserved in bacteria
SaSA184_RS02675	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA184_RS02680	COG1268	BioY protein
SaSA184_RS02685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA184_RS02705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA184_RS02730	COG1217	gtp-binding protein TYPA
SaSA184_RS02765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA184_RS02775	COG0762	integral membrane protein
SaSA184_RS02780	COG2302	S4 RNA-binding domain
SaSA184_RS02785	COG3599	regulation of cell shape
SaSA184_RS02805	COG0542	response to heat
SaSA184_RS02815	COG4703	Protein of unknown function (DUF1797)
SaSA184_RS02820	COG0765	amino acid transport
SaSA184_RS02825	COG1126	abc transporter atp-binding protein
SaSA184_RS02840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA184_RS02845	COG1570	exodeoxyribonuclease VII activity
SaSA184_RS02850	COG1722	exodeoxyribonuclease VII activity
SaSA184_RS02860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA184_RS02865	COG1438	arginine binding
SaSA184_RS02870	COG0497	DNA recombination
SaSA184_RS02875	COG1307	EDD domain protein, DegV family
SaSA184_RS02880	COG2755	lipolytic protein G-D-S-L family
SaSA184_RS02925	COG1078	dGTPase activity
SaSA184_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA184_RS02960	COG2884	Cell division ATP-binding protein ftsE
SaSA184_RS02965	COG2177	Part of the ABC transporter FtsEX involved in
SaSA184_RS02990	COG0436	Aminotransferase
SaSA184_RS02995	COG0017	Asparaginyl-tRNA synthetase
SaSA184_RS03020	COG1660	Displays ATPase and GTPase activities
SaSA184_RS03045	COG0254	rRNA binding
SaSA184_RS03050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA184_RS03055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA184_RS03060	COG0716	FMN binding
SaSA184_RS03065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA184_RS03065	COG1605	Chorismate mutase
SaSA184_RS03075	COG0335	large ribosomal subunit rRNA binding
SaSA184_RS03085	COG0772	Belongs to the SEDS family
SaSA184_RS03105	COG0560	Phosphoserine phosphatase
SaSA184_RS03120	COG0148	phosphopyruvate hydratase activity
SaSA184_RS03140	COG1316	TRANSCRIPTIONal
SaSA184_RS03235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA184_RS03325	COG1136	(ABC) transporter
SaSA184_RS03340	COG0586	Pfam SNARE associated Golgi protein
SaSA184_RS03345	COG4619	ABC transporter
SaSA184_RS03350	COG0390	transport system, permease component
SaSA184_RS03360	COG0583	DNA-binding transcription factor activity
SaSA184_RS03370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA184_RS03375	COG2211	Major facilitator Superfamily
SaSA184_RS03380	COG3250	beta-galactosidase activity
SaSA184_RS03385	COG2186	Transcriptional regulator
SaSA184_RS03405	COG1609	Transcriptional regulator
SaSA184_RS03420	COG0438	transferase activity, transferring glycosyl groups
SaSA184_RS03445	COG0765	amino acid transport
SaSA184_RS03450	COG0765	amino acid transport
SaSA184_RS03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA184_RS03460	COG1126	abc transporter atp-binding protein
SaSA184_RS03465	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS03470	COG5002	protein histidine kinase activity
SaSA184_RS03475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA184_RS03480	COG2832	Protein of unknown function (DUF454)
SaSA184_RS03490	COG1196	nuclear chromosome segregation
SaSA184_RS03495	COG0561	phosphatase activity
SaSA184_RS03500	COG0561	phosphatase activity
SaSA184_RS03505	COG0552	protein localization to endoplasmic reticulum
SaSA184_RS03520	COG3689	TIGRFAM TIGR03943 family protein
SaSA184_RS03525	COG0701	Predicted permease
SaSA184_RS03540	COG2183	response to ionizing radiation
SaSA184_RS03545	COG3091	SprT-like family
SaSA184_RS03550	COG1983	PspC domain protein
SaSA184_RS03590	COG0826	peptidase U32
SaSA184_RS03595	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA184_RS03605	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA184_RS03620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA184_RS03620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA184_RS03645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA184_RS03680	COG0772	Belongs to the SEDS family
SaSA184_RS03700	COG0768	penicillin binding
SaSA184_RS03715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA184_RS03745	COG2011	ABC-type metal ion transport system permease component
SaSA184_RS03750	COG1464	Belongs to the NlpA lipoprotein family
SaSA184_RS03755	COG0513	Belongs to the DEAD box helicase family
SaSA184_RS03775	COG1596	polysaccharide export
SaSA184_RS03775	COG1555	photosystem II stabilization
SaSA184_RS03790	COG1609	Transcriptional regulator
SaSA184_RS03795	COG0657	acetylesterase activity
SaSA184_RS03800	COG2264	protein methyltransferase activity
SaSA184_RS03810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA184_RS03815	COG3711	transcriptional antiterminator
SaSA184_RS03835	COG3835	regulator
SaSA184_RS03840	COG1929	Belongs to the glycerate kinase type-1 family
SaSA184_RS03845	COG2610	gluconate transmembrane transporter activity
SaSA184_RS03855	COG1846	Transcriptional regulator
SaSA184_RS03860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA184_RS03870	COG0363	glucosamine-6-phosphate deaminase activity
SaSA184_RS03875	COG0435	Glutathione S-transferase
SaSA184_RS03880	COG1187	pseudouridine synthase activity
SaSA184_RS03905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA184_RS03910	COG4122	O-methyltransferase activity
SaSA184_RS03920	COG4894	glucomannan catabolic process
SaSA184_RS03925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA184_RS03935	COG1442	glycosyl transferase family 8
SaSA184_RS03950	COG1476	TRANSCRIPTIONal
SaSA184_RS03970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA184_RS03975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA184_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
SaSA184_RS03995	COG0726	polysaccharide deacetylase
SaSA184_RS04005	COG0513	Belongs to the DEAD box helicase family
SaSA184_RS04015	COG1956	GAF domain-containing protein
SaSA184_RS04020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA184_RS04035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA184_RS04065	COG4721	ABC-type cobalt transport system, permease component
SaSA184_RS04080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA184_RS04090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA184_RS04095	COG0352	thiamine-phosphate diphosphorylase activity
SaSA184_RS04100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA184_RS04110	COG4109	DRTGG domain
SaSA184_RS04115	COG0024	Methionine aminopeptidase
SaSA184_RS04125	COG2246	polysaccharide biosynthetic process
SaSA184_RS04130	COG4708	membrane
SaSA184_RS04135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA184_RS04140	COG1597	lipid kinase activity
SaSA184_RS04145	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA184_RS04175	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA184_RS04205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA184_RS04215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA184_RS04240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA184_RS04240	COG0072	phenylalanine-tRNA ligase activity
SaSA184_RS04245	COG2321	neutral zinc metallopeptidase
SaSA184_RS04255	COG1074	ATP-dependent DNA helicase activity
SaSA184_RS04265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA184_RS04270	COG0488	(ABC) transporter
SaSA184_RS04275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA184_RS04280	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA184_RS04280	COG0022	dehydrogenase e1 component
SaSA184_RS04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA184_RS04295	COG0095	Lipoate-protein ligase
SaSA184_RS04300	COG3442	glutamine amidotransferase
SaSA184_RS04305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA184_RS04310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA184_RS04335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA184_RS04355	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA184_RS04360	COG1518	maintenance of DNA repeat elements
SaSA184_RS04365	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA184_RS04385	COG0481	GTPase activity
SaSA184_RS04395	COG1418	mRNA catabolic process
SaSA184_RS04400	COG0456	acetyltransferase
SaSA184_RS04410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SaSA184_RS04440	COG1131	(ABC) transporter
SaSA184_RS04445	COG1725	Transcriptional regulator
SaSA184_RS04455	COG0205	6-phosphofructokinase activity
SaSA184_RS04460	COG0469	pyruvate kinase activity
SaSA184_RS04465	COG0681	Belongs to the peptidase S26 family
SaSA184_RS04475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA184_RS04480	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA184_RS04485	COG0765	amino acid transport
SaSA184_RS04490	COG1126	abc transporter atp-binding protein
SaSA184_RS04510	COG1072	(Pantothenic acid kinase))
SaSA184_RS04515	COG2813	Specifically methylates the guanine in position
SaSA184_RS04520	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA184_RS04535	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA184_RS04555	COG3764	Sortase (surface protein transpeptidase)
SaSA184_RS04560	COG0346	lactoylglutathione lyase activity
SaSA184_RS04585	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA184_RS04595	COG1464	Belongs to the NlpA lipoprotein family
SaSA184_RS04610	COG1136	(ABC) transporter
SaSA184_RS04620	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS04625	COG5002	protein histidine kinase activity
SaSA184_RS04630	COG4974	Belongs to the 'phage' integrase family
SaSA184_RS04655	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SaSA184_RS04660	COG5002	protein histidine kinase activity
SaSA184_RS04665	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS04675	COG0704	Plays a role in the regulation of phosphate uptake
SaSA184_RS04680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA184_RS04685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA184_RS04690	COG0581	inorganic phosphate transmembrane transporter activity
SaSA184_RS04695	COG0573	inorganic phosphate transmembrane transporter activity
SaSA184_RS04715	COG0483	inositol monophosphate 1-phosphatase activity
SaSA184_RS04720	COG4476	Belongs to the UPF0223 family
SaSA184_RS04730	COG0196	riboflavin kinase activity
SaSA184_RS04735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SaSA184_RS04780	COG1136	(ABC) transporter
SaSA184_RS04785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA184_RS04790	COG0758	DNA mediated transformation
SaSA184_RS04795	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA184_RS04800	COG4604	ABC transporter, ATP-binding protein
SaSA184_RS04805	COG4605	iron ion homeostasis
SaSA184_RS04810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA184_RS04815	COG0110	maltose O-acetyltransferase activity
SaSA184_RS04830	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA184_RS04835	COG1966	Carbon starvation protein
SaSA184_RS04840	COG3279	Response regulator of the LytR AlgR family
SaSA184_RS04845	COG3275	phosphorelay sensor kinase activity
SaSA184_RS04890	COG0505	Belongs to the CarA family
SaSA184_RS04905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA184_RS04920	COG0488	(ABC) transporter
SaSA184_RS04930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA184_RS04945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA184_RS04995	COG0095	Lipoate-protein ligase
SaSA184_RS05005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA184_RS05010	COG4684	Psort location CytoplasmicMembrane, score
SaSA184_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA184_RS05060	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA184_RS05095	COG0431	NADPH-dependent FMN reductase
SaSA184_RS05095	COG1053	succinate dehydrogenase
SaSA184_RS05095	COG3976	FMN-binding domain protein
SaSA184_RS05105	COG2233	PERMEase
SaSA184_RS05140	COG0564	pseudouridine synthase activity
SaSA184_RS05145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA184_RS05150	COG2357	RelA SpoT domain protein
SaSA184_RS05165	COG1104	cysteine desulfurase activity
SaSA184_RS05185	COG0628	permease
SaSA184_RS05200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA184_RS05245	COG0561	phosphatase activity
SaSA184_RS05270	COG1177	transmembrane transport
SaSA184_RS05275	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA184_RS05285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA184_RS05290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA184_RS05310	COG0285	dihydrofolate synthase activity
SaSA184_RS05315	COG2962	Rard protein
SaSA184_RS05335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA184_RS05430	COG2261	transglycosylase associated protein
SaSA184_RS05455	COG1115	amino acid carrier protein
SaSA184_RS05460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA184_RS05470	COG1346	cytolysis
SaSA184_RS05485	COG0539	negative regulation of cytoplasmic translation
SaSA184_RS05505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA184_RS05515	COG0187	DNA topoisomerase II activity
SaSA184_RS05525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA184_RS05535	COG1083	cytidylyl-transferase
SaSA184_RS05535	COG2755	lipolytic protein G-D-S-L family
SaSA184_RS05570	COG1442	glycosyl transferase family 8
SaSA184_RS05570	COG1216	Glycosyl transferase, family 2
SaSA184_RS05585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA184_RS05590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA184_RS05675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaSA184_RS05680	COG3527	Alpha-acetolactate decarboxylase
SaSA184_RS05685	COG0028	Belongs to the TPP enzyme family
SaSA184_RS05690	COG0457	Tetratricopeptide repeat
SaSA184_RS05695	COG0628	permease
SaSA184_RS05705	COG1051	belongs to the nudix hydrolase family
SaSA184_RS05715	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA184_RS05725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA184_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA184_RS05740	COG2384	SAM-dependent methyltransferase
SaSA184_RS05765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SaSA184_RS05765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SaSA184_RS05770	COG0300	oxidoreductase activity
SaSA184_RS05785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaSA184_RS05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA184_RS05815	COG1573	uracil-dna glycosylase
SaSA184_RS05820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA184_RS05830	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA184_RS05845	COG0534	Mate efflux family protein
SaSA184_RS05900	COG0833	amino acid
SaSA184_RS05940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA184_RS05950	COG3425	synthase
SaSA184_RS05965	COG1272	protein, Hemolysin III
SaSA184_RS06010	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS06015	COG2357	RelA SpoT domain protein
SaSA184_RS06030	COG1132	(ABC) transporter
SaSA184_RS06045	COG0488	(ABC) transporter
SaSA184_RS06075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA184_RS06075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA184_RS06075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA184_RS06080	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA184_RS06085	COG1349	DNA-binding transcription factor activity
SaSA184_RS06140	COG1837	Belongs to the UPF0109 family
SaSA184_RS06145	COG0228	four-way junction DNA binding
SaSA184_RS06155	COG1136	(ABC) transporter
SaSA184_RS06160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA184_RS06170	COG0505	Belongs to the CarA family
SaSA184_RS06180	COG0564	pseudouridine synthase activity
SaSA184_RS06195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA184_RS06215	COG0301	tRNA thio-modification
SaSA184_RS06220	COG1104	cysteine desulfurase activity
SaSA184_RS06230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA184_RS06270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA184_RS06280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA184_RS06310	COG2244	polysaccharide biosynthetic process
SaSA184_RS06315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA184_RS06320	COG1120	ATPase activity
SaSA184_RS06355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA184_RS06360	COG1253	flavin adenine dinucleotide binding
SaSA184_RS06365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA184_RS06370	COG1242	4 iron, 4 sulfur cluster binding
SaSA184_RS06375	COG0671	phosphoesterase, PA-phosphatase related
SaSA184_RS06380	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA184_RS06425	COG0297	glycogen (starch) synthase activity
SaSA184_RS06465	COG3475	LICD family
SaSA184_RS06480	COG0463	Glycosyl transferase, family 2
SaSA184_RS06485	COG1215	transferase activity, transferring glycosyl groups
SaSA184_RS06495	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA184_RS06500	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA184_RS06505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA184_RS06510	COG0358	DNA primase activity
SaSA184_RS06515	COG1970	mechanosensitive ion channel activity
SaSA184_RS06530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA184_RS06535	COG0004	ammonium transporteR
SaSA184_RS06545	COG1054	Belongs to the UPF0176 family
SaSA184_RS06555	COG2271	Major facilitator Superfamily
SaSA184_RS06565	COG0058	SHG alpha-glucan phosphorylase activity
SaSA184_RS06570	COG1640	4-alpha-glucanotransferase
SaSA184_RS06575	COG1609	Transcriptional regulator
SaSA184_RS06585	COG1175	transmembrane transport
SaSA184_RS06590	COG3833	ABC-type maltose transport systems, permease component
SaSA184_RS06625	COG0438	transferase activity, transferring glycosyl groups
SaSA184_RS06675	COG0765	amino acid transport
SaSA184_RS06680	COG1126	abc transporter atp-binding protein
SaSA184_RS06705	COG2309	aminopeptidase activity
SaSA184_RS06720	COG1187	pseudouridine synthase activity
SaSA184_RS06725	COG0656	L-ascorbic acid biosynthetic process
SaSA184_RS06730	COG0778	Nitroreductase
SaSA184_RS06735	COG0346	lactoylglutathione lyase activity
SaSA184_RS06740	COG0463	Glycosyl transferase, family 2
SaSA184_RS06745	COG1113	amino acid transport
SaSA184_RS06750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SaSA184_RS06755	COG0557	exoribonuclease II activity
SaSA184_RS06780	COG1131	(ABC) transporter
SaSA184_RS06790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA184_RS06910	COG0233	cytoplasmic translational termination
SaSA184_RS06925	COG0444	Belongs to the ABC transporter superfamily
SaSA184_RS06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA184_RS06935	COG0601	transmembrane transport
SaSA184_RS06940	COG0747	negative chemotaxis
SaSA184_RS06945	COG0081	regulation of translation
SaSA184_RS06950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA184_RS06960	COG1473	amidohydrolase
SaSA184_RS06965	COG0583	DNA-binding transcription factor activity
SaSA184_RS06980	COG1674	ftsk spoiiie
SaSA184_RS06985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA184_RS07010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA184_RS07045	COG0673	inositol 2-dehydrogenase activity
SaSA184_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA184_RS07110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA184_RS07110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA184_RS07130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA184_RS07150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA184_RS07155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA184_RS07165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA184_RS07190	COG0470	DNA polymerase III
SaSA184_RS07200	COG0517	IMP dehydrogenase activity
SaSA184_RS07220	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA184_RS07240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA184_RS07245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA184_RS07255	COG0531	amino acid
SaSA184_RS07280	COG1187	pseudouridine synthase activity
SaSA184_RS07315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA184_RS07330	COG1827	regulation of RNA biosynthetic process
SaSA184_RS07345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA184_RS07350	COG1254	Belongs to the acylphosphatase family
SaSA184_RS07360	COG0765	amino acid transport
SaSA184_RS07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA184_RS07380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA184_RS07405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA184_RS07415	COG1484	DNA-dependent DNA replication
SaSA184_RS07435	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS07450	COG1704	LemA family
SaSA184_RS07455	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA184_RS07465	COG0569	domain protein
SaSA184_RS07495	COG1114	Component of the transport system for branched-chain amino acids
SaSA184_RS07500	COG1063	alcohol dehydrogenase
SaSA184_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA184_RS07530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA184_RS07540	COG0217	transcriptional regulatory protein
SaSA184_RS07550	COG2376	Dihydroxyacetone kinase
SaSA184_RS07555	COG1309	transcriptional regulator
SaSA184_RS07565	COG2376	Dihydroxyacetone kinase
SaSA184_RS07570	COG1461	Dihydroxyacetone kinase
SaSA184_RS07575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA184_RS07580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA184_RS07590	COG0789	Transcriptional regulator
SaSA184_RS07605	COG2226	methyltransferase
SaSA184_RS07610	COG0799	negative regulation of ribosome biogenesis
SaSA184_RS07625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA184_RS07630	COG1534	Rna-binding protein
SaSA184_RS07635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA184_RS07640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaSA184_RS07655	COG0154	amidase activity
SaSA184_RS07660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA184_RS07665	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA184_RS07665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA184_RS07675	COG0517	IMP dehydrogenase activity
SaSA184_RS07685	COG1335	isochorismatase
SaSA184_RS07690	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA184_RS07695	COG0436	Aminotransferase
SaSA184_RS07700	COG0589	response to stress
SaSA184_RS07720	COG4989	oxidoreductase activity
SaSA184_RS07725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA184_RS07740	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA184_RS07760	COG1940	carbohydrate kinase activity
SaSA184_RS07765	COG1263	PTS System
SaSA184_RS07765	COG2190	(PTS) system
SaSA184_RS07765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA184_RS07770	COG1621	beta-fructofuranosidase activity
SaSA184_RS07775	COG1609	Transcriptional regulator
SaSA184_RS07780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA184_RS07790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA184_RS07820	COG2131	deaminase
SaSA184_RS07825	COG0006	proline dipeptidase activity
SaSA184_RS07860	COG0629	single-stranded DNA binding
SaSA184_RS07865	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA184_RS07870	COG1194	a g-specific adenine glycosylase
SaSA184_RS07880	COG3118	belongs to the thioredoxin family
SaSA184_RS07905	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA184_RS07915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA184_RS07930	COG1882	Formate acetyltransferase
SaSA184_RS07935	COG3576	pyridoxamine 5-phosphate
SaSA184_RS07940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA184_RS07955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA184_RS07965	COG2814	Major facilitator Superfamily
SaSA184_RS07970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA184_RS07990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA184_RS07995	COG4988	ABC transporter
SaSA184_RS08000	COG1294	oxidase, subunit
SaSA184_RS08010	COG1252	NADH dehydrogenase
SaSA184_RS08035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA184_RS08040	COG0789	Transcriptional regulator
SaSA184_RS08055	COG2081	HI0933 family
SaSA184_RS08085	COG0456	acetyltransferase
SaSA184_RS08105	COG3942	CHAP domain
SaSA184_RS08110	COG0174	glutamine synthetase
SaSA184_RS08115	COG0789	Transcriptional regulator
SaSA184_RS08130	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA184_RS08160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA184_RS08185	COG1162	GTPase activity
SaSA184_RS08205	COG0693	protein deglycase activity
SaSA184_RS08215	COG0084	hydrolase, TatD family'
SaSA184_RS08245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA184_RS08250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA184_RS08255	COG1696	Membrane protein involved in D-alanine export
SaSA184_RS08285	COG3314	Sporulation integral membrane protein YlbJ
SaSA184_RS08295	COG4175	Glycine betaine
SaSA184_RS08295	COG3448	diguanylate cyclase activity
SaSA184_RS08335	COG3775	system Galactitol-specific IIC component
SaSA184_RS08340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA184_RS08350	COG1609	Transcriptional regulator
SaSA184_RS08400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA184_RS08435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA184_RS08440	COG1428	Deoxynucleoside kinase
SaSA184_RS08450	COG0542	response to heat
SaSA184_RS08455	COG4463	regulation of RNA biosynthetic process
SaSA184_RS08465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA184_RS08475	COG0450	alkyl hydroperoxide reductase
SaSA184_RS08490	COG0025	NhaP-type Na H and K H
SaSA184_RS08500	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA184_RS08505	COG3590	peptidase
SaSA184_RS08535	COG1609	Transcriptional regulator
SaSA184_RS08545	COG3716	PTS system mannose fructose sorbose family IID component
SaSA184_RS08550	COG3715	PTS system
SaSA184_RS08555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA184_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA184_RS08620	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA184_RS08620	COG1388	LysM domain
SaSA184_RS08635	COG4589	Belongs to the CDS family
SaSA184_RS08640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SaSA184_RS08645	COG1862	Preprotein translocase
SaSA184_RS08665	COG3290	protein histidine kinase activity
SaSA184_RS08670	COG4565	transcriptional regulatory protein
SaSA184_RS08675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA184_RS08685	COG3842	ATPase activity
SaSA184_RS08755	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA184_RS08775	COG1363	Peptidase, m42
SaSA184_RS08790	COG2207	Transcriptional regulator
SaSA184_RS08790	COG4753	response regulator
SaSA184_RS08795	COG2972	Histidine kinase
SaSA184_RS08800	COG3716	PTS system mannose fructose sorbose family IID component
SaSA184_RS08805	COG3715	PTS system
SaSA184_RS08835	COG1131	(ABC) transporter
SaSA184_RS08855	COG3290	protein histidine kinase activity
SaSA184_RS08875	COG2190	(PTS) system
SaSA184_RS08875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA184_RS08875	COG1263	PTS System
SaSA184_RS08880	COG5002	protein histidine kinase activity
SaSA184_RS08895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA184_RS08900	COG0581	inorganic phosphate transmembrane transporter activity
SaSA184_RS08920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA184_RS08935	COG0789	Transcriptional regulator
SaSA184_RS08970	COG0456	acetyltransferase
SaSA184_RS08975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA184_RS09060	COG1131	(ABC) transporter
SaSA184_RS09070	COG1396	sequence-specific DNA binding
SaSA184_RS09090	COG2897	thiosulfate sulfurtransferase activity
SaSA184_RS09105	COG0371	Dehydrogenase
SaSA184_RS09130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA184_RS09145	COG0745	RESPONSE REGULATOR receiver
SaSA184_RS09160	COG0495	leucyl-tRNA aminoacylation
SaSA184_RS09165	COG2814	Major facilitator Superfamily
SaSA184_RS09170	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA184_RS09200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA184_RS09205	COG0564	pseudouridine synthase activity
SaSA184_RS09225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA184_RS09230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA184_RS09250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA184_RS09255	COG1116	anion transmembrane transporter activity
SaSA184_RS09255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA184_RS09265	COG0561	phosphatase activity
SaSA184_RS09270	COG2514	catechol 2,3-dioxygenase activity
SaSA184_RS09275	COG3022	response to hydroperoxide
SaSA184_RS09280	COG0602	queuosine metabolic process
SaSA184_RS09300	COG1328	CTP reductase activity
SaSA184_RS09320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA184_RS09330	COG1393	Belongs to the ArsC family
SaSA184_RS09335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA184_RS09345	COG2818	Glycosylase
SaSA184_RS09385	COG0018	arginyl-trna synthetase
SaSA184_RS09395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA184_RS09400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA184_RS09410	COG0124	histidyl-tRNA synthetase
SaSA184_RS09420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA184_RS09435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA184_RS09445	COG0784	Response regulator, receiver
SaSA184_RS09450	COG1125	glycine betaine transport
SaSA184_RS09450	COG0517	IMP dehydrogenase activity
SaSA184_RS09455	COG1174	glycine betaine transport
SaSA184_RS09470	COG3759	membrane
SaSA184_RS09500	COG0305	Participates in initiation and elongation during chromosome replication
SaSA184_RS09525	COG0482	sulfurtransferase activity
SaSA184_RS09530	COG1760	l-serine dehydratase
SaSA184_RS09535	COG1760	l-serine dehydratase
SaSA184_RS09540	COG0741	lytic transglycosylase activity
SaSA184_RS09565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA184_RS09570	COG0612	Peptidase, M16
SaSA184_RS09575	COG0612	Peptidase, M16
SaSA184_RS09580	COG2501	S4 domain
SaSA184_RS09600	COG0516	GMP reductase activity
SaSA184_RS09600	COG0517	IMP dehydrogenase activity
SaSA184_RS09625	COG0454	-acetyltransferase
SaSA184_RS09630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA184_RS09640	COG0549	Belongs to the carbamate kinase family
SaSA184_RS09660	COG0488	(ABC) transporter
SaSA184_RS09665	COG4485	Bacterial membrane protein, YfhO
SaSA184_RS09685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA184_RS09690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA184_RS09695	COG1475	DNA binding