locus-tag	class	description
SaSA220_RS00010	COG0592	DNA-directed DNA polymerase activity
SaSA220_RS00030	COG0012	GTP binding
SaSA220_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA220_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA220_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA220_RS00225	COG1695	Transcriptional regulator
SaSA220_RS00240	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA220_RS00275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA220_RS00310	COG1131	(ABC) transporter
SaSA220_RS00320	COG1263	PTS System
SaSA220_RS00320	COG2190	(PTS) system
SaSA220_RS00320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA220_RS00325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA220_RS00330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA220_RS00335	COG0275	rRNA processing
SaSA220_RS00345	COG0768	penicillin binding
SaSA220_RS00355	COG0513	Belongs to the DEAD box helicase family
SaSA220_RS00370	COG1126	abc transporter atp-binding protein
SaSA220_RS00380	COG0492	ferredoxin-NADP+ reductase activity
SaSA220_RS00385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA220_RS00400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA220_RS00430	COG0116	Belongs to the methyltransferase superfamily
SaSA220_RS00440	COG1854	S-ribosylhomocysteine lyase activity
SaSA220_RS00445	COG4372	Transposase
SaSA220_RS00445	COG1418	mRNA catabolic process
SaSA220_RS00455	COG1131	(ABC) transporter
SaSA220_RS00480	COG0194	GDP metabolic process
SaSA220_RS00490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA220_RS00495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA220_RS00500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA220_RS00500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA220_RS00510	COG0515	serine threonine protein kinase
SaSA220_RS00510	COG2815	serine threonine protein kinase
SaSA220_RS00520	COG4585	Histidine kinase
SaSA220_RS00525	COG2197	response regulator
SaSA220_RS00535	COG1098	S1 RNA binding domain
SaSA220_RS00545	COG1349	DNA-binding transcription factor activity
SaSA220_RS00555	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA220_RS00575	COG1739	Uncharacterized protein family UPF0029
SaSA220_RS00580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaSA220_RS00585	COG1040	competence protein
SaSA220_RS00620	COG0527	aspartate kinase activity
SaSA220_RS00635	COG1024	Enoyl-CoA hydratase
SaSA220_RS00645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA220_RS00655	COG2070	2-Nitropropane dioxygenase
SaSA220_RS00660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA220_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA220_RS00670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA220_RS00685	COG0439	Biotin carboxylase
SaSA220_RS00705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SaSA220_RS00720	COG3716	PTS system mannose fructose sorbose family IID component
SaSA220_RS00725	COG3715	PTS system
SaSA220_RS00740	COG0561	phosphatase activity
SaSA220_RS00755	COG2252	PERMEase
SaSA220_RS00760	COG0802	atpase or kinase
SaSA220_RS00770	COG1316	TRANSCRIPTIONal
SaSA220_RS00780	COG0537	adenosine 5'-monophosphoramidase activity
SaSA220_RS00795	COG1131	(ABC) transporter
SaSA220_RS00800	COG4473	ABC transporter
SaSA220_RS00810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA220_RS00825	COG0195	Participates in both transcription termination and antitermination
SaSA220_RS00830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA220_RS00840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA220_RS00845	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA220_RS00870	COG2860	membrane
SaSA220_RS00880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA220_RS00880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA220_RS00885	COG1832	CoA-binding protein
SaSA220_RS00920	COG1268	BioY protein
SaSA220_RS00925	COG1234	tRNA 3'-trailer cleavage
SaSA220_RS00940	COG0166	Belongs to the GPI family
SaSA220_RS00945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA220_RS00950	COG0457	Tetratricopeptide repeat
SaSA220_RS00950	COG0705	Rhomboid family
SaSA220_RS00955	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA220_RS00960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA220_RS00975	COG0706	membrane insertase activity
SaSA220_RS01080	COG0436	Aminotransferase
SaSA220_RS01100	COG0416	fatty acid biosynthetic process
SaSA220_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA220_RS01110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA220_RS01115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA220_RS01130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA220_RS01170	COG0395	ABC-type sugar transport system, permease component
SaSA220_RS01185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA220_RS01200	COG1737	Transcriptional regulator
SaSA220_RS01210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA220_RS01230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA220_RS01245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA220_RS01255	COG2755	lipolytic protein G-D-S-L family
SaSA220_RS01255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA220_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
SaSA220_RS01260	COG1454	alcohol dehydrogenase
SaSA220_RS01265	COG1064	alcohol dehydrogenase
SaSA220_RS01275	COG0534	Mate efflux family protein
SaSA220_RS01385	COG0201	protein transport
SaSA220_RS01390	COG0563	adenylate kinase activity
SaSA220_RS01405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SaSA220_RS01415	COG0202	RNA polymerase activity
SaSA220_RS01465	COG1121	(ABC) transporter
SaSA220_RS01470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA220_RS01480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA220_RS01485	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA220_RS01485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA220_RS01510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA220_RS01515	COG1459	type II secretion system
SaSA220_RS01560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SaSA220_RS01565	COG1363	Peptidase, m42
SaSA220_RS01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA220_RS01585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA220_RS01600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA220_RS01620	COG1346	cytolysis
SaSA220_RS01630	COG0601	transmembrane transport
SaSA220_RS01635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA220_RS01640	COG1122	ATPase activity
SaSA220_RS01655	COG0366	Alpha amylase catalytic
SaSA220_RS01660	COG0366	Alpha amylase catalytic
SaSA220_RS01675	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA220_RS01705	COG1045	serine acetyltransferase
SaSA220_RS01715	COG0215	cysteine-tRNA ligase activity
SaSA220_RS01720	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA220_RS01745	COG1476	TRANSCRIPTIONal
SaSA220_RS01750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA220_RS01805	COG1396	sequence-specific DNA binding
SaSA220_RS01820	COG1732	Glycine betaine
SaSA220_RS01950	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA220_RS01965	COG0443	Heat shock 70 kDa protein
SaSA220_RS01975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA220_RS01985	COG0351	phosphomethylpyrimidine kinase
SaSA220_RS01990	COG4720	Psort location CytoplasmicMembrane, score
SaSA220_RS02000	COG0668	transmembrane transport
SaSA220_RS02030	COG0756	dUTP diphosphatase activity
SaSA220_RS02045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA220_RS02060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA220_RS02065	COG1879	ABC-type sugar transport system periplasmic component
SaSA220_RS02070	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA220_RS02085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA220_RS02090	COG1609	Transcriptional regulator
SaSA220_RS02100	COG0577	efflux transmembrane transporter activity
SaSA220_RS02105	COG1136	(ABC) transporter
SaSA220_RS02115	COG5002	protein histidine kinase activity
SaSA220_RS02130	COG0191	fructose-bisphosphate aldolase activity
SaSA220_RS02150	COG1461	Dihydroxyacetone kinase
SaSA220_RS02170	COG1126	abc transporter atp-binding protein
SaSA220_RS02175	COG0765	amino acid transport
SaSA220_RS02195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA220_RS02205	COG0719	Fe-S assembly protein
SaSA220_RS02210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SaSA220_RS02220	COG0719	Fe-S assembly protein
SaSA220_RS02225	COG1686	Belongs to the peptidase S11 family
SaSA220_RS02230	COG1686	Belongs to the peptidase S11 family
SaSA220_RS02235	COG4166	transmembrane transport
SaSA220_RS02240	COG0601	transmembrane transport
SaSA220_RS02245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA220_RS02250	COG0444	Belongs to the ABC transporter superfamily
SaSA220_RS02255	COG4608	Belongs to the ABC transporter superfamily
SaSA220_RS02310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA220_RS02320	COG2153	protein acetylation
SaSA220_RS02330	COG1216	Glycosyl transferase, family 2
SaSA220_RS02330	COG1442	glycosyl transferase family 8
SaSA220_RS02390	COG0789	Transcriptional regulator
SaSA220_RS02395	COG1063	alcohol dehydrogenase
SaSA220_RS02400	COG0656	L-ascorbic acid biosynthetic process
SaSA220_RS02440	COG2226	methyltransferase
SaSA220_RS02450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA220_RS02455	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA220_RS02460	COG3775	system Galactitol-specific IIC component
SaSA220_RS02465	COG0235	Class ii aldolase
SaSA220_RS02480	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA220_RS02485	COG2207	Transcriptional regulator
SaSA220_RS02495	COG1175	transmembrane transport
SaSA220_RS02500	COG0395	ABC-type sugar transport system, permease component
SaSA220_RS02520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA220_RS02590	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA220_RS02605	COG2315	Protein conserved in bacteria
SaSA220_RS02625	COG0742	ribosomal rna small subunit methyltransferase
SaSA220_RS02640	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA220_RS02650	COG4470	Protein conserved in bacteria
SaSA220_RS02670	COG1132	(ABC) transporter
SaSA220_RS02675	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA220_RS02680	COG1268	BioY protein
SaSA220_RS02685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA220_RS02705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA220_RS02730	COG1217	gtp-binding protein TYPA
SaSA220_RS02765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA220_RS02775	COG0762	integral membrane protein
SaSA220_RS02780	COG2302	S4 RNA-binding domain
SaSA220_RS02785	COG3599	regulation of cell shape
SaSA220_RS02805	COG0542	response to heat
SaSA220_RS02815	COG4703	Protein of unknown function (DUF1797)
SaSA220_RS02820	COG0765	amino acid transport
SaSA220_RS02825	COG1126	abc transporter atp-binding protein
SaSA220_RS02830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA220_RS02840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA220_RS02845	COG1570	exodeoxyribonuclease VII activity
SaSA220_RS02850	COG1722	exodeoxyribonuclease VII activity
SaSA220_RS02860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA220_RS02865	COG1438	arginine binding
SaSA220_RS02870	COG0497	DNA recombination
SaSA220_RS02875	COG1307	EDD domain protein, DegV family
SaSA220_RS02880	COG2755	lipolytic protein G-D-S-L family
SaSA220_RS02925	COG1078	dGTPase activity
SaSA220_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA220_RS02960	COG2884	Cell division ATP-binding protein ftsE
SaSA220_RS02965	COG2177	Part of the ABC transporter FtsEX involved in
SaSA220_RS02985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA220_RS02985	COG1199	ATP-dependent helicase activity
SaSA220_RS02990	COG0436	Aminotransferase
SaSA220_RS02995	COG0017	Asparaginyl-tRNA synthetase
SaSA220_RS03020	COG1660	Displays ATPase and GTPase activities
SaSA220_RS03045	COG0254	rRNA binding
SaSA220_RS03050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA220_RS03055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA220_RS03060	COG0716	FMN binding
SaSA220_RS03065	COG1605	Chorismate mutase
SaSA220_RS03065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA220_RS03075	COG0335	large ribosomal subunit rRNA binding
SaSA220_RS03085	COG0772	Belongs to the SEDS family
SaSA220_RS03105	COG0560	Phosphoserine phosphatase
SaSA220_RS03120	COG0148	phosphopyruvate hydratase activity
SaSA220_RS03140	COG1316	TRANSCRIPTIONal
SaSA220_RS03155	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA220_RS03155	COG3942	CHAP domain
SaSA220_RS03235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA220_RS03325	COG1136	(ABC) transporter
SaSA220_RS03340	COG0586	Pfam SNARE associated Golgi protein
SaSA220_RS03345	COG4619	ABC transporter
SaSA220_RS03350	COG0390	transport system, permease component
SaSA220_RS03360	COG0583	DNA-binding transcription factor activity
SaSA220_RS03370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA220_RS03380	COG2211	Major facilitator Superfamily
SaSA220_RS03385	COG3250	beta-galactosidase activity
SaSA220_RS03390	COG2186	Transcriptional regulator
SaSA220_RS03410	COG1609	Transcriptional regulator
SaSA220_RS03425	COG0438	transferase activity, transferring glycosyl groups
SaSA220_RS03450	COG0765	amino acid transport
SaSA220_RS03455	COG0765	amino acid transport
SaSA220_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA220_RS03465	COG1126	abc transporter atp-binding protein
SaSA220_RS03470	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS03475	COG5002	protein histidine kinase activity
SaSA220_RS03480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA220_RS03485	COG2832	Protein of unknown function (DUF454)
SaSA220_RS03495	COG1196	nuclear chromosome segregation
SaSA220_RS03505	COG0552	protein localization to endoplasmic reticulum
SaSA220_RS03520	COG3689	TIGRFAM TIGR03943 family protein
SaSA220_RS03525	COG0701	Predicted permease
SaSA220_RS03540	COG2183	response to ionizing radiation
SaSA220_RS03545	COG3091	SprT-like family
SaSA220_RS03550	COG1983	PspC domain protein
SaSA220_RS03590	COG0826	peptidase U32
SaSA220_RS03595	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA220_RS03605	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA220_RS03620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA220_RS03620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA220_RS03645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA220_RS03680	COG0772	Belongs to the SEDS family
SaSA220_RS03700	COG0768	penicillin binding
SaSA220_RS03715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA220_RS03745	COG2011	ABC-type metal ion transport system permease component
SaSA220_RS03750	COG1464	Belongs to the NlpA lipoprotein family
SaSA220_RS03755	COG0513	Belongs to the DEAD box helicase family
SaSA220_RS03765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA220_RS03770	COG0204	Acyl-transferase
SaSA220_RS03775	COG1555	photosystem II stabilization
SaSA220_RS03775	COG1596	polysaccharide export
SaSA220_RS03790	COG1609	Transcriptional regulator
SaSA220_RS03795	COG0657	acetylesterase activity
SaSA220_RS03800	COG2264	protein methyltransferase activity
SaSA220_RS03810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA220_RS03815	COG3711	transcriptional antiterminator
SaSA220_RS03820	COG2190	(PTS) system
SaSA220_RS03820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA220_RS03820	COG1263	PTS System
SaSA220_RS03835	COG3835	regulator
SaSA220_RS03840	COG1929	Belongs to the glycerate kinase type-1 family
SaSA220_RS03845	COG2610	gluconate transmembrane transporter activity
SaSA220_RS03860	COG1846	Transcriptional regulator
SaSA220_RS03865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA220_RS03875	COG0363	glucosamine-6-phosphate deaminase activity
SaSA220_RS03880	COG0435	Glutathione S-transferase
SaSA220_RS03885	COG1187	pseudouridine synthase activity
SaSA220_RS03910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA220_RS03915	COG4122	O-methyltransferase activity
SaSA220_RS03925	COG4894	glucomannan catabolic process
SaSA220_RS03930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA220_RS03940	COG1442	glycosyl transferase family 8
SaSA220_RS03955	COG1476	TRANSCRIPTIONal
SaSA220_RS03970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA220_RS03975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA220_RS03980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA220_RS03995	COG1012	belongs to the aldehyde dehydrogenase family
SaSA220_RS04010	COG0513	Belongs to the DEAD box helicase family
SaSA220_RS04020	COG1956	GAF domain-containing protein
SaSA220_RS04025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA220_RS04035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SaSA220_RS04035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SaSA220_RS04040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA220_RS04070	COG4721	ABC-type cobalt transport system, permease component
SaSA220_RS04075	COG1122	ATPase activity
SaSA220_RS04095	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA220_RS04100	COG0352	thiamine-phosphate diphosphorylase activity
SaSA220_RS04105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA220_RS04115	COG4109	DRTGG domain
SaSA220_RS04120	COG0024	Methionine aminopeptidase
SaSA220_RS04135	COG4708	membrane
SaSA220_RS04140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA220_RS04145	COG1597	lipid kinase activity
SaSA220_RS04150	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA220_RS04155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SaSA220_RS04180	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA220_RS04210	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA220_RS04220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA220_RS04245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA220_RS04245	COG0072	phenylalanine-tRNA ligase activity
SaSA220_RS04250	COG2321	neutral zinc metallopeptidase
SaSA220_RS04260	COG1074	ATP-dependent DNA helicase activity
SaSA220_RS04270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA220_RS04275	COG0488	(ABC) transporter
SaSA220_RS04280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA220_RS04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA220_RS04285	COG0022	dehydrogenase e1 component
SaSA220_RS04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA220_RS04300	COG0095	Lipoate-protein ligase
SaSA220_RS04305	COG3442	glutamine amidotransferase
SaSA220_RS04310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA220_RS04315	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA220_RS04340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA220_RS04360	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA220_RS04365	COG1518	maintenance of DNA repeat elements
SaSA220_RS04370	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA220_RS04390	COG0481	GTPase activity
SaSA220_RS04405	COG1418	mRNA catabolic process
SaSA220_RS04410	COG0456	acetyltransferase
SaSA220_RS04420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SaSA220_RS04440	COG0398	Pfam SNARE associated Golgi protein
SaSA220_RS04450	COG1131	(ABC) transporter
SaSA220_RS04455	COG1725	Transcriptional regulator
SaSA220_RS04465	COG0205	6-phosphofructokinase activity
SaSA220_RS04470	COG0469	pyruvate kinase activity
SaSA220_RS04475	COG0681	Belongs to the peptidase S26 family
SaSA220_RS04485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA220_RS04490	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA220_RS04495	COG0765	amino acid transport
SaSA220_RS04500	COG1126	abc transporter atp-binding protein
SaSA220_RS04520	COG1072	(Pantothenic acid kinase))
SaSA220_RS04525	COG2813	Specifically methylates the guanine in position
SaSA220_RS04530	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA220_RS04545	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA220_RS04565	COG3764	Sortase (surface protein transpeptidase)
SaSA220_RS04570	COG0346	lactoylglutathione lyase activity
SaSA220_RS04590	COG2188	Transcriptional regulator
SaSA220_RS04595	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA220_RS04605	COG1464	Belongs to the NlpA lipoprotein family
SaSA220_RS04620	COG1136	(ABC) transporter
SaSA220_RS04630	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS04635	COG5002	protein histidine kinase activity
SaSA220_RS04640	COG4974	Belongs to the 'phage' integrase family
SaSA220_RS04665	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SaSA220_RS04670	COG5002	protein histidine kinase activity
SaSA220_RS04675	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS04685	COG0704	Plays a role in the regulation of phosphate uptake
SaSA220_RS04690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA220_RS04695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA220_RS04700	COG0581	inorganic phosphate transmembrane transporter activity
SaSA220_RS04705	COG0573	inorganic phosphate transmembrane transporter activity
SaSA220_RS04720	COG0483	inositol monophosphate 1-phosphatase activity
SaSA220_RS04725	COG4476	Belongs to the UPF0223 family
SaSA220_RS04735	COG0196	riboflavin kinase activity
SaSA220_RS04740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SaSA220_RS04780	COG1136	(ABC) transporter
SaSA220_RS04790	COG0758	DNA mediated transformation
SaSA220_RS04795	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA220_RS04800	COG4604	ABC transporter, ATP-binding protein
SaSA220_RS04805	COG4605	iron ion homeostasis
SaSA220_RS04810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA220_RS04815	COG0110	maltose O-acetyltransferase activity
SaSA220_RS04825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA220_RS04830	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA220_RS04835	COG1966	Carbon starvation protein
SaSA220_RS04840	COG3279	Response regulator of the LytR AlgR family
SaSA220_RS04845	COG3275	phosphorelay sensor kinase activity
SaSA220_RS04890	COG0505	Belongs to the CarA family
SaSA220_RS04905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA220_RS04920	COG0488	(ABC) transporter
SaSA220_RS04930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA220_RS04945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA220_RS04995	COG0095	Lipoate-protein ligase
SaSA220_RS05005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA220_RS05010	COG4684	Psort location CytoplasmicMembrane, score
SaSA220_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA220_RS05060	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA220_RS05075	COG1942	4-Oxalocrotonate Tautomerase
SaSA220_RS05095	COG0431	NADPH-dependent FMN reductase
SaSA220_RS05095	COG3976	FMN-binding domain protein
SaSA220_RS05095	COG1053	succinate dehydrogenase
SaSA220_RS05105	COG2233	PERMEase
SaSA220_RS05140	COG0564	pseudouridine synthase activity
SaSA220_RS05145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA220_RS05150	COG2357	RelA SpoT domain protein
SaSA220_RS05165	COG1104	cysteine desulfurase activity
SaSA220_RS05185	COG0628	permease
SaSA220_RS05200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA220_RS05245	COG0561	phosphatase activity
SaSA220_RS05270	COG1177	transmembrane transport
SaSA220_RS05275	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA220_RS05285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA220_RS05290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA220_RS05310	COG0285	dihydrofolate synthase activity
SaSA220_RS05315	COG2962	Rard protein
SaSA220_RS05335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA220_RS05430	COG2261	transglycosylase associated protein
SaSA220_RS05455	COG1115	amino acid carrier protein
SaSA220_RS05460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA220_RS05470	COG1346	cytolysis
SaSA220_RS05485	COG0539	negative regulation of cytoplasmic translation
SaSA220_RS05505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA220_RS05515	COG0187	DNA topoisomerase II activity
SaSA220_RS05520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA220_RS05525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA220_RS05535	COG2755	lipolytic protein G-D-S-L family
SaSA220_RS05535	COG1083	cytidylyl-transferase
SaSA220_RS05550	COG2089	acid synthase
SaSA220_RS05570	COG1216	Glycosyl transferase, family 2
SaSA220_RS05570	COG1442	glycosyl transferase family 8
SaSA220_RS05585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA220_RS05590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA220_RS05610	COG1316	TRANSCRIPTIONal
SaSA220_RS05660	COG3842	ATPase activity
SaSA220_RS05675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaSA220_RS05680	COG3527	Alpha-acetolactate decarboxylase
SaSA220_RS05685	COG0028	Belongs to the TPP enzyme family
SaSA220_RS05690	COG0457	Tetratricopeptide repeat
SaSA220_RS05695	COG0628	permease
SaSA220_RS05705	COG1051	belongs to the nudix hydrolase family
SaSA220_RS05710	COG5492	domain, Protein
SaSA220_RS05715	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA220_RS05725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA220_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA220_RS05740	COG2384	SAM-dependent methyltransferase
SaSA220_RS05765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SaSA220_RS05765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SaSA220_RS05770	COG0300	oxidoreductase activity
SaSA220_RS05785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaSA220_RS05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA220_RS05815	COG1573	uracil-dna glycosylase
SaSA220_RS05820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA220_RS05830	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA220_RS05845	COG0534	Mate efflux family protein
SaSA220_RS05900	COG0833	amino acid
SaSA220_RS05940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA220_RS05950	COG3425	synthase
SaSA220_RS05965	COG1272	protein, Hemolysin III
SaSA220_RS06010	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS06015	COG2357	RelA SpoT domain protein
SaSA220_RS06030	COG1132	(ABC) transporter
SaSA220_RS06045	COG0488	(ABC) transporter
SaSA220_RS06075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA220_RS06075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA220_RS06075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA220_RS06080	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA220_RS06085	COG1349	DNA-binding transcription factor activity
SaSA220_RS06145	COG1837	Belongs to the UPF0109 family
SaSA220_RS06150	COG0228	four-way junction DNA binding
SaSA220_RS06155	COG0577	efflux transmembrane transporter activity
SaSA220_RS06160	COG1136	(ABC) transporter
SaSA220_RS06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA220_RS06175	COG0505	Belongs to the CarA family
SaSA220_RS06185	COG0564	pseudouridine synthase activity
SaSA220_RS06195	COG0583	DNA-binding transcription factor activity
SaSA220_RS06200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA220_RS06220	COG0301	tRNA thio-modification
SaSA220_RS06225	COG1104	cysteine desulfurase activity
SaSA220_RS06235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA220_RS06260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaSA220_RS06265	COG1368	sulfuric ester hydrolase activity
SaSA220_RS06275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA220_RS06285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA220_RS06315	COG2244	polysaccharide biosynthetic process
SaSA220_RS06320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA220_RS06325	COG1120	ATPase activity
SaSA220_RS06360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA220_RS06365	COG1253	flavin adenine dinucleotide binding
SaSA220_RS06370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA220_RS06375	COG1242	4 iron, 4 sulfur cluster binding
SaSA220_RS06380	COG0671	phosphoesterase, PA-phosphatase related
SaSA220_RS06385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA220_RS06415	COG0681	Belongs to the peptidase S26 family
SaSA220_RS06425	COG0297	glycogen (starch) synthase activity
SaSA220_RS06465	COG3475	LICD family
SaSA220_RS06480	COG0463	Glycosyl transferase, family 2
SaSA220_RS06485	COG1215	transferase activity, transferring glycosyl groups
SaSA220_RS06495	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA220_RS06500	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA220_RS06505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA220_RS06510	COG0358	DNA primase activity
SaSA220_RS06515	COG1970	mechanosensitive ion channel activity
SaSA220_RS06530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA220_RS06535	COG0004	ammonium transporteR
SaSA220_RS06545	COG1054	Belongs to the UPF0176 family
SaSA220_RS06555	COG2271	Major facilitator Superfamily
SaSA220_RS06565	COG0058	SHG alpha-glucan phosphorylase activity
SaSA220_RS06570	COG1640	4-alpha-glucanotransferase
SaSA220_RS06575	COG1609	Transcriptional regulator
SaSA220_RS06585	COG1175	transmembrane transport
SaSA220_RS06590	COG3833	ABC-type maltose transport systems, permease component
SaSA220_RS06625	COG0438	transferase activity, transferring glycosyl groups
SaSA220_RS06675	COG0765	amino acid transport
SaSA220_RS06680	COG1126	abc transporter atp-binding protein
SaSA220_RS06705	COG2309	aminopeptidase activity
SaSA220_RS06720	COG1187	pseudouridine synthase activity
SaSA220_RS06725	COG0656	L-ascorbic acid biosynthetic process
SaSA220_RS06730	COG0778	Nitroreductase
SaSA220_RS06735	COG0346	lactoylglutathione lyase activity
SaSA220_RS06740	COG0463	Glycosyl transferase, family 2
SaSA220_RS06745	COG1113	amino acid transport
SaSA220_RS06750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SaSA220_RS06755	COG0557	exoribonuclease II activity
SaSA220_RS06780	COG1131	(ABC) transporter
SaSA220_RS06790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA220_RS06855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SaSA220_RS06860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SaSA220_RS06890	COG1702	phosphate starvation-inducible protein PhoH
SaSA220_RS06915	COG0233	cytoplasmic translational termination
SaSA220_RS06930	COG0444	Belongs to the ABC transporter superfamily
SaSA220_RS06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA220_RS06940	COG0601	transmembrane transport
SaSA220_RS06945	COG0747	negative chemotaxis
SaSA220_RS06950	COG0081	regulation of translation
SaSA220_RS06955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA220_RS06965	COG1473	amidohydrolase
SaSA220_RS06970	COG0583	DNA-binding transcription factor activity
SaSA220_RS06985	COG1674	ftsk spoiiie
SaSA220_RS06990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA220_RS07015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA220_RS07050	COG0673	inositol 2-dehydrogenase activity
SaSA220_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA220_RS07115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA220_RS07115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA220_RS07135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA220_RS07145	COG0708	Exodeoxyribonuclease III
SaSA220_RS07150	COG1393	Belongs to the ArsC family
SaSA220_RS07155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA220_RS07160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA220_RS07170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA220_RS07195	COG0470	DNA polymerase III
SaSA220_RS07205	COG0517	IMP dehydrogenase activity
SaSA220_RS07225	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA220_RS07245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA220_RS07250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA220_RS07260	COG0531	amino acid
SaSA220_RS07285	COG1187	pseudouridine synthase activity
SaSA220_RS07320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA220_RS07335	COG1827	regulation of RNA biosynthetic process
SaSA220_RS07350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA220_RS07355	COG1254	Belongs to the acylphosphatase family
SaSA220_RS07365	COG0765	amino acid transport
SaSA220_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA220_RS07385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA220_RS07410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA220_RS07420	COG1484	DNA-dependent DNA replication
SaSA220_RS07435	COG5002	protein histidine kinase activity
SaSA220_RS07440	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS07450	COG0501	Belongs to the peptidase M48B family
SaSA220_RS07455	COG1704	LemA family
SaSA220_RS07460	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA220_RS07465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA220_RS07470	COG0569	domain protein
SaSA220_RS07500	COG1114	Component of the transport system for branched-chain amino acids
SaSA220_RS07505	COG1063	alcohol dehydrogenase
SaSA220_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA220_RS07535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA220_RS07545	COG0217	transcriptional regulatory protein
SaSA220_RS07555	COG2376	Dihydroxyacetone kinase
SaSA220_RS07560	COG1309	transcriptional regulator
SaSA220_RS07570	COG2376	Dihydroxyacetone kinase
SaSA220_RS07575	COG1461	Dihydroxyacetone kinase
SaSA220_RS07580	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA220_RS07585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA220_RS07595	COG0789	Transcriptional regulator
SaSA220_RS07600	COG1323	Belongs to the UPF0348 family
SaSA220_RS07610	COG2226	methyltransferase
SaSA220_RS07615	COG0799	negative regulation of ribosome biogenesis
SaSA220_RS07625	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA220_RS07630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA220_RS07635	COG1534	Rna-binding protein
SaSA220_RS07640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA220_RS07645	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaSA220_RS07660	COG0154	amidase activity
SaSA220_RS07665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA220_RS07670	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA220_RS07670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA220_RS07680	COG0517	IMP dehydrogenase activity
SaSA220_RS07690	COG1335	isochorismatase
SaSA220_RS07695	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA220_RS07700	COG0436	Aminotransferase
SaSA220_RS07705	COG0589	response to stress
SaSA220_RS07715	COG0252	asparaginase activity
SaSA220_RS07725	COG4989	oxidoreductase activity
SaSA220_RS07730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA220_RS07745	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA220_RS07750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SaSA220_RS07760	COG1482	cell wall glycoprotein biosynthetic process
SaSA220_RS07765	COG1940	carbohydrate kinase activity
SaSA220_RS07770	COG1263	PTS System
SaSA220_RS07770	COG2190	(PTS) system
SaSA220_RS07770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA220_RS07775	COG1621	beta-fructofuranosidase activity
SaSA220_RS07780	COG1609	Transcriptional regulator
SaSA220_RS07785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA220_RS07795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA220_RS07825	COG2131	deaminase
SaSA220_RS07830	COG0006	proline dipeptidase activity
SaSA220_RS07865	COG0629	single-stranded DNA binding
SaSA220_RS07870	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA220_RS07875	COG1194	a g-specific adenine glycosylase
SaSA220_RS07885	COG3118	belongs to the thioredoxin family
SaSA220_RS07910	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA220_RS07915	COG0681	Belongs to the peptidase S26 family
SaSA220_RS07920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA220_RS07935	COG1882	Formate acetyltransferase
SaSA220_RS07940	COG3576	pyridoxamine 5-phosphate
SaSA220_RS07945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA220_RS07960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA220_RS07970	COG2814	Major facilitator Superfamily
SaSA220_RS07975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA220_RS07990	COG0142	geranyltranstransferase activity
SaSA220_RS07995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA220_RS08000	COG4988	ABC transporter
SaSA220_RS08005	COG1294	oxidase, subunit
SaSA220_RS08010	COG1271	oxidase subunit
SaSA220_RS08015	COG1252	NADH dehydrogenase
SaSA220_RS08035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SaSA220_RS08040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA220_RS08045	COG0789	Transcriptional regulator
SaSA220_RS08060	COG2081	HI0933 family
SaSA220_RS08090	COG0456	acetyltransferase
SaSA220_RS08110	COG3942	CHAP domain
SaSA220_RS08115	COG0174	glutamine synthetase
SaSA220_RS08120	COG0789	Transcriptional regulator
SaSA220_RS08135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA220_RS08165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA220_RS08190	COG1162	GTPase activity
SaSA220_RS08210	COG0693	protein deglycase activity
SaSA220_RS08220	COG0084	hydrolase, TatD family'
SaSA220_RS08250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA220_RS08255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA220_RS08260	COG1696	Membrane protein involved in D-alanine export
SaSA220_RS08290	COG3314	Sporulation integral membrane protein YlbJ
SaSA220_RS08300	COG3448	diguanylate cyclase activity
SaSA220_RS08300	COG4175	Glycine betaine
SaSA220_RS08340	COG3775	system Galactitol-specific IIC component
SaSA220_RS08345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA220_RS08355	COG1609	Transcriptional regulator
SaSA220_RS08405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA220_RS08440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA220_RS08445	COG1428	Deoxynucleoside kinase
SaSA220_RS08455	COG0542	response to heat
SaSA220_RS08460	COG4463	regulation of RNA biosynthetic process
SaSA220_RS08470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA220_RS08480	COG0450	alkyl hydroperoxide reductase
SaSA220_RS08495	COG0025	NhaP-type Na H and K H
SaSA220_RS08505	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA220_RS08510	COG3590	peptidase
SaSA220_RS08540	COG1609	Transcriptional regulator
SaSA220_RS08550	COG3716	PTS system mannose fructose sorbose family IID component
SaSA220_RS08555	COG3715	PTS system
SaSA220_RS08560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA220_RS08565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA220_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA220_RS08620	COG2176	DNA-directed DNA polymerase activity
SaSA220_RS08625	COG1388	LysM domain
SaSA220_RS08625	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA220_RS08640	COG4589	Belongs to the CDS family
SaSA220_RS08645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SaSA220_RS08650	COG1862	Preprotein translocase
SaSA220_RS08670	COG3290	protein histidine kinase activity
SaSA220_RS08675	COG4565	transcriptional regulatory protein
SaSA220_RS08680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA220_RS08690	COG3842	ATPase activity
SaSA220_RS08760	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA220_RS08780	COG1363	Peptidase, m42
SaSA220_RS08795	COG2207	Transcriptional regulator
SaSA220_RS08795	COG4753	response regulator
SaSA220_RS08800	COG2972	Histidine kinase
SaSA220_RS08805	COG3716	PTS system mannose fructose sorbose family IID component
SaSA220_RS08810	COG3715	PTS system
SaSA220_RS08840	COG1131	(ABC) transporter
SaSA220_RS08860	COG3290	protein histidine kinase activity
SaSA220_RS08880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA220_RS08880	COG1263	PTS System
SaSA220_RS08880	COG2190	(PTS) system
SaSA220_RS08885	COG5002	protein histidine kinase activity
SaSA220_RS08900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA220_RS08905	COG0581	inorganic phosphate transmembrane transporter activity
SaSA220_RS08925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA220_RS08940	COG0789	Transcriptional regulator
SaSA220_RS08975	COG0456	acetyltransferase
SaSA220_RS08980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA220_RS09065	COG1131	(ABC) transporter
SaSA220_RS09075	COG1396	sequence-specific DNA binding
SaSA220_RS09095	COG2897	thiosulfate sulfurtransferase activity
SaSA220_RS09110	COG0371	Dehydrogenase
SaSA220_RS09135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA220_RS09150	COG0745	RESPONSE REGULATOR receiver
SaSA220_RS09165	COG0495	leucyl-tRNA aminoacylation
SaSA220_RS09170	COG2814	Major facilitator Superfamily
SaSA220_RS09175	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA220_RS09200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA220_RS09205	COG0564	pseudouridine synthase activity
SaSA220_RS09225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA220_RS09230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA220_RS09250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA220_RS09255	COG1116	anion transmembrane transporter activity
SaSA220_RS09255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA220_RS09265	COG0561	phosphatase activity
SaSA220_RS09270	COG2514	catechol 2,3-dioxygenase activity
SaSA220_RS09275	COG3022	response to hydroperoxide
SaSA220_RS09280	COG0602	queuosine metabolic process
SaSA220_RS09300	COG1328	CTP reductase activity
SaSA220_RS09320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA220_RS09330	COG1393	Belongs to the ArsC family
SaSA220_RS09335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA220_RS09340	COG1058	Belongs to the CinA family
SaSA220_RS09340	COG1546	Belongs to the CinA family
SaSA220_RS09345	COG2818	Glycosylase
SaSA220_RS09385	COG0018	arginyl-trna synthetase
SaSA220_RS09395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA220_RS09400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA220_RS09410	COG0124	histidyl-tRNA synthetase
SaSA220_RS09420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA220_RS09435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA220_RS09445	COG0784	Response regulator, receiver
SaSA220_RS09450	COG1125	glycine betaine transport
SaSA220_RS09450	COG0517	IMP dehydrogenase activity
SaSA220_RS09455	COG1174	glycine betaine transport
SaSA220_RS09460	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA220_RS09460	COG0392	lysyltransferase activity
SaSA220_RS09470	COG3759	membrane
SaSA220_RS09500	COG0305	Participates in initiation and elongation during chromosome replication
SaSA220_RS09525	COG0482	sulfurtransferase activity
SaSA220_RS09530	COG1760	l-serine dehydratase
SaSA220_RS09535	COG1760	l-serine dehydratase
SaSA220_RS09540	COG0741	lytic transglycosylase activity
SaSA220_RS09565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA220_RS09570	COG0612	Peptidase, M16
SaSA220_RS09575	COG0612	Peptidase, M16
SaSA220_RS09580	COG2501	S4 domain
SaSA220_RS09600	COG0516	GMP reductase activity
SaSA220_RS09600	COG0517	IMP dehydrogenase activity
SaSA220_RS09625	COG0454	-acetyltransferase
SaSA220_RS09630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA220_RS09640	COG0549	Belongs to the carbamate kinase family
SaSA220_RS09655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA220_RS09660	COG0488	(ABC) transporter
SaSA220_RS09665	COG4485	Bacterial membrane protein, YfhO
SaSA220_RS09685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA220_RS09690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA220_RS09695	COG1475	DNA binding