locus-tag	class	description
SaSA30_RS00030	COG0012	GTP binding
SaSA30_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA30_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA30_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA30_RS00230	COG1695	Transcriptional regulator
SaSA30_RS00245	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA30_RS00280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_RS00315	COG1131	(ABC) transporter
SaSA30_RS00325	COG2190	(PTS) system
SaSA30_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_RS00325	COG1263	PTS System
SaSA30_RS00330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA30_RS00335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA30_RS00340	COG0275	rRNA processing
SaSA30_RS00350	COG0768	penicillin binding
SaSA30_RS00360	COG0513	Belongs to the DEAD box helicase family
SaSA30_RS00375	COG1126	abc transporter atp-binding protein
SaSA30_RS00385	COG0492	ferredoxin-NADP+ reductase activity
SaSA30_RS00390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA30_RS00405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_RS00435	COG0116	Belongs to the methyltransferase superfamily
SaSA30_RS00445	COG1854	S-ribosylhomocysteine lyase activity
SaSA30_RS00450	COG1418	mRNA catabolic process
SaSA30_RS00450	COG4372	Transposase
SaSA30_RS00460	COG1131	(ABC) transporter
SaSA30_RS00470	COG4585	Histidine kinase
SaSA30_RS00485	COG0194	GDP metabolic process
SaSA30_RS00495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA30_RS00500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA30_RS00505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA30_RS00505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA30_RS00515	COG2815	serine threonine protein kinase
SaSA30_RS00515	COG0515	serine threonine protein kinase
SaSA30_RS00525	COG4585	Histidine kinase
SaSA30_RS00530	COG2197	response regulator
SaSA30_RS00540	COG1098	S1 RNA binding domain
SaSA30_RS00550	COG1349	DNA-binding transcription factor activity
SaSA30_RS00560	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA30_RS00580	COG1739	Uncharacterized protein family UPF0029
SaSA30_RS00590	COG1040	competence protein
SaSA30_RS00625	COG0527	aspartate kinase activity
SaSA30_RS00640	COG1024	Enoyl-CoA hydratase
SaSA30_RS00650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA30_RS00665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA30_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_RS00675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA30_RS00690	COG0439	Biotin carboxylase
SaSA30_RS00710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SaSA30_RS00725	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_RS00730	COG3715	PTS system
SaSA30_RS00745	COG0561	phosphatase activity
SaSA30_RS00760	COG2252	PERMEase
SaSA30_RS00765	COG0802	atpase or kinase
SaSA30_RS00775	COG1316	TRANSCRIPTIONal
SaSA30_RS00785	COG0537	adenosine 5'-monophosphoramidase activity
SaSA30_RS00800	COG1131	(ABC) transporter
SaSA30_RS00805	COG4473	ABC transporter
SaSA30_RS00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA30_RS00830	COG0195	Participates in both transcription termination and antitermination
SaSA30_RS00835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA30_RS00845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA30_RS00850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA30_RS00875	COG2860	membrane
SaSA30_RS00885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA30_RS00885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA30_RS00890	COG1832	CoA-binding protein
SaSA30_RS00925	COG1268	BioY protein
SaSA30_RS00930	COG1234	tRNA 3'-trailer cleavage
SaSA30_RS00945	COG0166	Belongs to the GPI family
SaSA30_RS00950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA30_RS00955	COG0705	Rhomboid family
SaSA30_RS00955	COG0457	Tetratricopeptide repeat
SaSA30_RS00960	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA30_RS00965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA30_RS00980	COG0706	membrane insertase activity
SaSA30_RS01085	COG0436	Aminotransferase
SaSA30_RS01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA30_RS01115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA30_RS01120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA30_RS01135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA30_RS01175	COG0395	ABC-type sugar transport system, permease component
SaSA30_RS01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA30_RS01200	COG3458	cephalosporin-C deacetylase activity
SaSA30_RS01205	COG1737	Transcriptional regulator
SaSA30_RS01215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA30_RS01235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA30_RS01250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA30_RS01260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA30_RS01260	COG2755	lipolytic protein G-D-S-L family
SaSA30_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
SaSA30_RS01265	COG1454	alcohol dehydrogenase
SaSA30_RS01270	COG1064	alcohol dehydrogenase
SaSA30_RS01280	COG0534	Mate efflux family protein
SaSA30_RS01395	COG0563	adenylate kinase activity
SaSA30_RS01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SaSA30_RS01420	COG0202	RNA polymerase activity
SaSA30_RS01470	COG1121	(ABC) transporter
SaSA30_RS01475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA30_RS01485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA30_RS01490	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA30_RS01490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_RS01515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA30_RS01520	COG1459	type II secretion system
SaSA30_RS01570	COG1363	Peptidase, m42
SaSA30_RS01585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA30_RS01590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_RS01605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA30_RS01625	COG1346	cytolysis
SaSA30_RS01635	COG0601	transmembrane transport
SaSA30_RS01640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA30_RS01645	COG1122	ATPase activity
SaSA30_RS01660	COG0366	Alpha amylase catalytic
SaSA30_RS01665	COG0366	Alpha amylase catalytic
SaSA30_RS01680	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA30_RS01710	COG1045	serine acetyltransferase
SaSA30_RS01720	COG0215	cysteine-tRNA ligase activity
SaSA30_RS01725	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA30_RS01750	COG1476	TRANSCRIPTIONal
SaSA30_RS01755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA30_RS01810	COG1396	sequence-specific DNA binding
SaSA30_RS01825	COG1732	Glycine betaine
SaSA30_RS01955	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA30_RS01970	COG0443	Heat shock 70 kDa protein
SaSA30_RS01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA30_RS01990	COG0351	phosphomethylpyrimidine kinase
SaSA30_RS01995	COG4720	Psort location CytoplasmicMembrane, score
SaSA30_RS02005	COG0668	transmembrane transport
SaSA30_RS02035	COG0756	dUTP diphosphatase activity
SaSA30_RS02050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA30_RS02065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA30_RS02070	COG1879	ABC-type sugar transport system periplasmic component
SaSA30_RS02075	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA30_RS02090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA30_RS02095	COG1609	Transcriptional regulator
SaSA30_RS02105	COG0577	efflux transmembrane transporter activity
SaSA30_RS02110	COG1136	(ABC) transporter
SaSA30_RS02135	COG0191	fructose-bisphosphate aldolase activity
SaSA30_RS02155	COG1461	Dihydroxyacetone kinase
SaSA30_RS02175	COG1126	abc transporter atp-binding protein
SaSA30_RS02180	COG0765	amino acid transport
SaSA30_RS02200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA30_RS02210	COG0719	Fe-S assembly protein
SaSA30_RS02225	COG0719	Fe-S assembly protein
SaSA30_RS02230	COG1686	Belongs to the peptidase S11 family
SaSA30_RS02235	COG1686	Belongs to the peptidase S11 family
SaSA30_RS02240	COG4166	transmembrane transport
SaSA30_RS02245	COG0601	transmembrane transport
SaSA30_RS02250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA30_RS02255	COG0444	Belongs to the ABC transporter superfamily
SaSA30_RS02260	COG4608	Belongs to the ABC transporter superfamily
SaSA30_RS02310	COG2137	regulation of response to DNA damage stimulus
SaSA30_RS02315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA30_RS02325	COG2153	protein acetylation
SaSA30_RS02335	COG1442	glycosyl transferase family 8
SaSA30_RS02335	COG1216	Glycosyl transferase, family 2
SaSA30_RS02395	COG0789	Transcriptional regulator
SaSA30_RS02400	COG1063	alcohol dehydrogenase
SaSA30_RS02405	COG0656	L-ascorbic acid biosynthetic process
SaSA30_RS02455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA30_RS02460	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA30_RS02465	COG3775	system Galactitol-specific IIC component
SaSA30_RS02485	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA30_RS02490	COG2207	Transcriptional regulator
SaSA30_RS02500	COG1175	transmembrane transport
SaSA30_RS02505	COG0395	ABC-type sugar transport system, permease component
SaSA30_RS02525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA30_RS02595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA30_RS02610	COG2315	Protein conserved in bacteria
SaSA30_RS02625	COG0742	ribosomal rna small subunit methyltransferase
SaSA30_RS02640	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA30_RS02650	COG4470	Protein conserved in bacteria
SaSA30_RS02670	COG1132	(ABC) transporter
SaSA30_RS02675	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA30_RS02680	COG1268	BioY protein
SaSA30_RS02685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA30_RS02705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA30_RS02730	COG1217	gtp-binding protein TYPA
SaSA30_RS02765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA30_RS02775	COG0762	integral membrane protein
SaSA30_RS02780	COG2302	S4 RNA-binding domain
SaSA30_RS02785	COG3599	regulation of cell shape
SaSA30_RS02805	COG0542	response to heat
SaSA30_RS02815	COG4703	Protein of unknown function (DUF1797)
SaSA30_RS02820	COG0765	amino acid transport
SaSA30_RS02825	COG1126	abc transporter atp-binding protein
SaSA30_RS02830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA30_RS02840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA30_RS02845	COG1570	exodeoxyribonuclease VII activity
SaSA30_RS02850	COG1722	exodeoxyribonuclease VII activity
SaSA30_RS02860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA30_RS02865	COG1438	arginine binding
SaSA30_RS02870	COG0497	DNA recombination
SaSA30_RS02875	COG1307	EDD domain protein, DegV family
SaSA30_RS02925	COG1078	dGTPase activity
SaSA30_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA30_RS02960	COG2884	Cell division ATP-binding protein ftsE
SaSA30_RS02965	COG2177	Part of the ABC transporter FtsEX involved in
SaSA30_RS02985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA30_RS02985	COG1199	ATP-dependent helicase activity
SaSA30_RS02990	COG0436	Aminotransferase
SaSA30_RS02995	COG0017	Asparaginyl-tRNA synthetase
SaSA30_RS03020	COG1660	Displays ATPase and GTPase activities
SaSA30_RS03045	COG0254	rRNA binding
SaSA30_RS03050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA30_RS03055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA30_RS03060	COG0716	FMN binding
SaSA30_RS03065	COG1605	Chorismate mutase
SaSA30_RS03065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA30_RS03075	COG0335	large ribosomal subunit rRNA binding
SaSA30_RS03085	COG0772	Belongs to the SEDS family
SaSA30_RS03105	COG0560	Phosphoserine phosphatase
SaSA30_RS03120	COG0148	phosphopyruvate hydratase activity
SaSA30_RS03140	COG1316	TRANSCRIPTIONal
SaSA30_RS03235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA30_RS03325	COG1136	(ABC) transporter
SaSA30_RS03340	COG0586	Pfam SNARE associated Golgi protein
SaSA30_RS03345	COG4619	ABC transporter
SaSA30_RS03350	COG0390	transport system, permease component
SaSA30_RS03360	COG0583	DNA-binding transcription factor activity
SaSA30_RS03370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_RS03375	COG2211	Major facilitator Superfamily
SaSA30_RS03380	COG3250	beta-galactosidase activity
SaSA30_RS03385	COG2186	Transcriptional regulator
SaSA30_RS03405	COG1609	Transcriptional regulator
SaSA30_RS03420	COG0438	transferase activity, transferring glycosyl groups
SaSA30_RS03445	COG0765	amino acid transport
SaSA30_RS03450	COG0765	amino acid transport
SaSA30_RS03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_RS03460	COG1126	abc transporter atp-binding protein
SaSA30_RS03465	COG0745	RESPONSE REGULATOR receiver
SaSA30_RS03470	COG5002	protein histidine kinase activity
SaSA30_RS03475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA30_RS03480	COG2832	Protein of unknown function (DUF454)
SaSA30_RS03490	COG1196	nuclear chromosome segregation
SaSA30_RS03495	COG0561	phosphatase activity
SaSA30_RS03500	COG0561	phosphatase activity
SaSA30_RS03505	COG0552	protein localization to endoplasmic reticulum
SaSA30_RS03520	COG3689	TIGRFAM TIGR03943 family protein
SaSA30_RS03525	COG0701	Predicted permease
SaSA30_RS03540	COG2183	response to ionizing radiation
SaSA30_RS03545	COG3091	SprT-like family
SaSA30_RS03550	COG1983	PspC domain protein
SaSA30_RS03590	COG0826	peptidase U32
SaSA30_RS03595	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA30_RS03605	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA30_RS03620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA30_RS03620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA30_RS03645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA30_RS03680	COG0772	Belongs to the SEDS family
SaSA30_RS03700	COG0768	penicillin binding
SaSA30_RS03715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA30_RS03745	COG2011	ABC-type metal ion transport system permease component
SaSA30_RS03750	COG1464	Belongs to the NlpA lipoprotein family
SaSA30_RS03755	COG0513	Belongs to the DEAD box helicase family
SaSA30_RS03765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA30_RS03770	COG0204	Acyl-transferase
SaSA30_RS03775	COG1596	polysaccharide export
SaSA30_RS03775	COG1555	photosystem II stabilization
SaSA30_RS03795	COG0657	acetylesterase activity
SaSA30_RS03800	COG2264	protein methyltransferase activity
SaSA30_RS03810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA30_RS03815	COG3711	transcriptional antiterminator
SaSA30_RS03835	COG3835	regulator
SaSA30_RS03840	COG1929	Belongs to the glycerate kinase type-1 family
SaSA30_RS03845	COG2610	gluconate transmembrane transporter activity
SaSA30_RS03855	COG1846	Transcriptional regulator
SaSA30_RS03860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA30_RS03875	COG0435	Glutathione S-transferase
SaSA30_RS03880	COG1187	pseudouridine synthase activity
SaSA30_RS03905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA30_RS03910	COG4122	O-methyltransferase activity
SaSA30_RS03925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA30_RS03935	COG1442	glycosyl transferase family 8
SaSA30_RS03950	COG1476	TRANSCRIPTIONal
SaSA30_RS03965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA30_RS03970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA30_RS03975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA30_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
SaSA30_RS03995	COG0726	polysaccharide deacetylase
SaSA30_RS04005	COG0513	Belongs to the DEAD box helicase family
SaSA30_RS04015	COG1956	GAF domain-containing protein
SaSA30_RS04020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA30_RS04035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA30_RS04065	COG4721	ABC-type cobalt transport system, permease component
SaSA30_RS04070	COG1122	ATPase activity
SaSA30_RS04080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA30_RS04090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA30_RS04095	COG0352	thiamine-phosphate diphosphorylase activity
SaSA30_RS04100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA30_RS04115	COG0024	Methionine aminopeptidase
SaSA30_RS04125	COG2246	polysaccharide biosynthetic process
SaSA30_RS04130	COG4708	membrane
SaSA30_RS04135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA30_RS04140	COG1597	lipid kinase activity
SaSA30_RS04145	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA30_RS04175	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA30_RS04205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA30_RS04215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA30_RS04240	COG0072	phenylalanine-tRNA ligase activity
SaSA30_RS04240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_RS04245	COG2321	neutral zinc metallopeptidase
SaSA30_RS04255	COG1074	ATP-dependent DNA helicase activity
SaSA30_RS04265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA30_RS04270	COG0488	(ABC) transporter
SaSA30_RS04275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA30_RS04280	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA30_RS04280	COG0022	dehydrogenase e1 component
SaSA30_RS04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA30_RS04295	COG0095	Lipoate-protein ligase
SaSA30_RS04300	COG3442	glutamine amidotransferase
SaSA30_RS04305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA30_RS04310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA30_RS04335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA30_RS04355	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA30_RS04360	COG1518	maintenance of DNA repeat elements
SaSA30_RS04365	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA30_RS04385	COG0481	GTPase activity
SaSA30_RS04395	COG1418	mRNA catabolic process
SaSA30_RS04430	COG0398	Pfam SNARE associated Golgi protein
SaSA30_RS04440	COG1131	(ABC) transporter
SaSA30_RS04445	COG1725	Transcriptional regulator
SaSA30_RS04455	COG0205	6-phosphofructokinase activity
SaSA30_RS04460	COG0469	pyruvate kinase activity
SaSA30_RS04465	COG0681	Belongs to the peptidase S26 family
SaSA30_RS04475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA30_RS04480	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA30_RS04485	COG0765	amino acid transport
SaSA30_RS04490	COG1126	abc transporter atp-binding protein
SaSA30_RS04510	COG1072	(Pantothenic acid kinase))
SaSA30_RS04520	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA30_RS04535	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA30_RS04555	COG3764	Sortase (surface protein transpeptidase)
SaSA30_RS04560	COG0346	lactoylglutathione lyase activity
SaSA30_RS04585	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA30_RS04595	COG1464	Belongs to the NlpA lipoprotein family
SaSA30_RS04620	COG0745	RESPONSE REGULATOR receiver
SaSA30_RS04625	COG5002	protein histidine kinase activity
SaSA30_RS04630	COG4974	Belongs to the 'phage' integrase family
SaSA30_RS04650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA30_RS04660	COG5002	protein histidine kinase activity
SaSA30_RS04665	COG0745	RESPONSE REGULATOR receiver
SaSA30_RS04675	COG0704	Plays a role in the regulation of phosphate uptake
SaSA30_RS04680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA30_RS04685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA30_RS04690	COG0581	inorganic phosphate transmembrane transporter activity
SaSA30_RS04695	COG0573	inorganic phosphate transmembrane transporter activity
SaSA30_RS04710	COG0483	inositol monophosphate 1-phosphatase activity
SaSA30_RS04715	COG4476	Belongs to the UPF0223 family
SaSA30_RS04725	COG0196	riboflavin kinase activity
SaSA30_RS04770	COG1136	(ABC) transporter
SaSA30_RS04775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA30_RS04785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA30_RS04790	COG4604	ABC transporter, ATP-binding protein
SaSA30_RS04795	COG4605	iron ion homeostasis
SaSA30_RS04800	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA30_RS04805	COG0110	maltose O-acetyltransferase activity
SaSA30_RS04815	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA30_RS04820	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA30_RS04825	COG1966	Carbon starvation protein
SaSA30_RS04830	COG3279	Response regulator of the LytR AlgR family
SaSA30_RS04835	COG3275	phosphorelay sensor kinase activity
SaSA30_RS04880	COG0505	Belongs to the CarA family
SaSA30_RS04895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA30_RS04910	COG0488	(ABC) transporter
SaSA30_RS04920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA30_RS04935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA30_RS04985	COG0095	Lipoate-protein ligase
SaSA30_RS04995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA30_RS05000	COG4684	Psort location CytoplasmicMembrane, score
SaSA30_RS05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA30_RS05050	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA30_RS05065	COG1942	4-Oxalocrotonate Tautomerase
SaSA30_RS05085	COG3976	FMN-binding domain protein
SaSA30_RS05085	COG1053	succinate dehydrogenase
SaSA30_RS05085	COG0431	NADPH-dependent FMN reductase
SaSA30_RS05095	COG2233	PERMEase
SaSA30_RS05130	COG0564	pseudouridine synthase activity
SaSA30_RS05135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA30_RS05140	COG2357	RelA SpoT domain protein
SaSA30_RS05155	COG1104	cysteine desulfurase activity
SaSA30_RS05175	COG0628	permease
SaSA30_RS05190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA30_RS05235	COG0561	phosphatase activity
SaSA30_RS05275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA30_RS05280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA30_RS05300	COG0285	dihydrofolate synthase activity
SaSA30_RS05305	COG2962	Rard protein
SaSA30_RS05325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA30_RS05420	COG2261	transglycosylase associated protein
SaSA30_RS05445	COG1115	amino acid carrier protein
SaSA30_RS05450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA30_RS05460	COG1346	cytolysis
SaSA30_RS05475	COG0539	negative regulation of cytoplasmic translation
SaSA30_RS05495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA30_RS05505	COG0187	DNA topoisomerase II activity
SaSA30_RS05510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA30_RS05515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA30_RS05525	COG2755	lipolytic protein G-D-S-L family
SaSA30_RS05525	COG1083	cytidylyl-transferase
SaSA30_RS05575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA30_RS05580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA30_RS05600	COG1316	TRANSCRIPTIONal
SaSA30_RS05650	COG3842	ATPase activity
SaSA30_RS05670	COG3527	Alpha-acetolactate decarboxylase
SaSA30_RS05675	COG0028	Belongs to the TPP enzyme family
SaSA30_RS05680	COG0457	Tetratricopeptide repeat
SaSA30_RS05685	COG0628	permease
SaSA30_RS05695	COG1051	belongs to the nudix hydrolase family
SaSA30_RS05700	COG5492	domain, Protein
SaSA30_RS05705	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA30_RS05715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA30_RS05720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA30_RS05730	COG2384	SAM-dependent methyltransferase
SaSA30_RS05760	COG0300	oxidoreductase activity
SaSA30_RS05775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaSA30_RS05780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA30_RS05805	COG1573	uracil-dna glycosylase
SaSA30_RS05810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA30_RS05820	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA30_RS05835	COG0534	Mate efflux family protein
SaSA30_RS05890	COG0833	amino acid
SaSA30_RS05930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA30_RS05940	COG3425	synthase
SaSA30_RS05955	COG1272	protein, Hemolysin III
SaSA30_RS06000	COG0745	RESPONSE REGULATOR receiver
SaSA30_RS06005	COG2357	RelA SpoT domain protein
SaSA30_RS06020	COG1132	(ABC) transporter
SaSA30_RS06035	COG0488	(ABC) transporter
SaSA30_RS06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA30_RS06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA30_RS06065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA30_RS06070	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA30_RS06075	COG1349	DNA-binding transcription factor activity
SaSA30_RS06135	COG1837	Belongs to the UPF0109 family
SaSA30_RS06140	COG0228	four-way junction DNA binding
SaSA30_RS06145	COG0577	efflux transmembrane transporter activity
SaSA30_RS06150	COG1136	(ABC) transporter
SaSA30_RS06155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA30_RS06165	COG0505	Belongs to the CarA family
SaSA30_RS06175	COG0564	pseudouridine synthase activity
SaSA30_RS06185	COG0583	DNA-binding transcription factor activity
SaSA30_RS06190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA30_RS06210	COG0301	tRNA thio-modification
SaSA30_RS06215	COG1104	cysteine desulfurase activity
SaSA30_RS06250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaSA30_RS06255	COG1368	sulfuric ester hydrolase activity
SaSA30_RS06265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA30_RS06275	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA30_RS06305	COG2244	polysaccharide biosynthetic process
SaSA30_RS06310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA30_RS06315	COG1120	ATPase activity
SaSA30_RS06350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA30_RS06355	COG1253	flavin adenine dinucleotide binding
SaSA30_RS06360	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA30_RS06365	COG1242	4 iron, 4 sulfur cluster binding
SaSA30_RS06370	COG0671	phosphoesterase, PA-phosphatase related
SaSA30_RS06375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA30_RS06420	COG0297	glycogen (starch) synthase activity
SaSA30_RS06475	COG0463	Glycosyl transferase, family 2
SaSA30_RS06480	COG1215	transferase activity, transferring glycosyl groups
SaSA30_RS06490	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA30_RS06495	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA30_RS06500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA30_RS06505	COG0358	DNA primase activity
SaSA30_RS06510	COG1970	mechanosensitive ion channel activity
SaSA30_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_RS06530	COG0004	ammonium transporteR
SaSA30_RS06540	COG1054	Belongs to the UPF0176 family
SaSA30_RS06550	COG2271	Major facilitator Superfamily
SaSA30_RS06560	COG0058	SHG alpha-glucan phosphorylase activity
SaSA30_RS06565	COG1640	4-alpha-glucanotransferase
SaSA30_RS06570	COG1609	Transcriptional regulator
SaSA30_RS06580	COG1175	transmembrane transport
SaSA30_RS06585	COG3833	ABC-type maltose transport systems, permease component
SaSA30_RS06620	COG0438	transferase activity, transferring glycosyl groups
SaSA30_RS06670	COG0765	amino acid transport
SaSA30_RS06675	COG1126	abc transporter atp-binding protein
SaSA30_RS06700	COG2309	aminopeptidase activity
SaSA30_RS06715	COG1187	pseudouridine synthase activity
SaSA30_RS06720	COG0656	L-ascorbic acid biosynthetic process
SaSA30_RS06725	COG0778	Nitroreductase
SaSA30_RS06730	COG0346	lactoylglutathione lyase activity
SaSA30_RS06735	COG0463	Glycosyl transferase, family 2
SaSA30_RS06740	COG1113	amino acid transport
SaSA30_RS06745	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SaSA30_RS06775	COG1131	(ABC) transporter
SaSA30_RS06785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA30_RS06850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SaSA30_RS06880	COG1702	phosphate starvation-inducible protein PhoH
SaSA30_RS06905	COG0233	cytoplasmic translational termination
SaSA30_RS06920	COG0444	Belongs to the ABC transporter superfamily
SaSA30_RS06930	COG0601	transmembrane transport
SaSA30_RS06935	COG0747	negative chemotaxis
SaSA30_RS06940	COG0081	regulation of translation
SaSA30_RS06945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA30_RS06955	COG1473	amidohydrolase
SaSA30_RS06960	COG0583	DNA-binding transcription factor activity
SaSA30_RS06975	COG1674	ftsk spoiiie
SaSA30_RS06980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA30_RS07005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA30_RS07040	COG0673	inositol 2-dehydrogenase activity
SaSA30_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_RS07105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_RS07105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_RS07125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA30_RS07135	COG0708	Exodeoxyribonuclease III
SaSA30_RS07140	COG1393	Belongs to the ArsC family
SaSA30_RS07145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA30_RS07150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_RS07160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA30_RS07195	COG0517	IMP dehydrogenase activity
SaSA30_RS07215	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA30_RS07235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA30_RS07240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA30_RS07250	COG0531	amino acid
SaSA30_RS07275	COG1187	pseudouridine synthase activity
SaSA30_RS07310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA30_RS07325	COG1827	regulation of RNA biosynthetic process
SaSA30_RS07340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA30_RS07345	COG1254	Belongs to the acylphosphatase family
SaSA30_RS07355	COG0765	amino acid transport
SaSA30_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_RS07375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA30_RS07400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA30_RS07410	COG1484	DNA-dependent DNA replication
SaSA30_RS07425	COG5002	protein histidine kinase activity
SaSA30_RS07430	COG0745	RESPONSE REGULATOR receiver
SaSA30_RS07440	COG0501	Belongs to the peptidase M48B family
SaSA30_RS07445	COG1704	LemA family
SaSA30_RS07450	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA30_RS07455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA30_RS07460	COG0569	domain protein
SaSA30_RS07490	COG1114	Component of the transport system for branched-chain amino acids
SaSA30_RS07495	COG1063	alcohol dehydrogenase
SaSA30_RS07520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_RS07525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA30_RS07535	COG0217	transcriptional regulatory protein
SaSA30_RS07545	COG2376	Dihydroxyacetone kinase
SaSA30_RS07550	COG1309	transcriptional regulator
SaSA30_RS07560	COG2376	Dihydroxyacetone kinase
SaSA30_RS07565	COG1461	Dihydroxyacetone kinase
SaSA30_RS07570	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA30_RS07575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_RS07585	COG0789	Transcriptional regulator
SaSA30_RS07590	COG1323	Belongs to the UPF0348 family
SaSA30_RS07600	COG2226	methyltransferase
SaSA30_RS07605	COG0799	negative regulation of ribosome biogenesis
SaSA30_RS07615	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA30_RS07620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA30_RS07625	COG1534	Rna-binding protein
SaSA30_RS07630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA30_RS07650	COG0154	amidase activity
SaSA30_RS07655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA30_RS07660	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA30_RS07660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA30_RS07670	COG0517	IMP dehydrogenase activity
SaSA30_RS07680	COG1335	isochorismatase
SaSA30_RS07685	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA30_RS07690	COG0436	Aminotransferase
SaSA30_RS07695	COG0589	response to stress
SaSA30_RS07705	COG0252	asparaginase activity
SaSA30_RS07715	COG4989	oxidoreductase activity
SaSA30_RS07720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA30_RS07735	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA30_RS07740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SaSA30_RS07755	COG1940	carbohydrate kinase activity
SaSA30_RS07760	COG1263	PTS System
SaSA30_RS07760	COG2190	(PTS) system
SaSA30_RS07760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_RS07765	COG1621	beta-fructofuranosidase activity
SaSA30_RS07770	COG1609	Transcriptional regulator
SaSA30_RS07775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA30_RS07785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA30_RS07815	COG2131	deaminase
SaSA30_RS07820	COG0006	proline dipeptidase activity
SaSA30_RS07855	COG0629	single-stranded DNA binding
SaSA30_RS07860	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA30_RS07865	COG1194	a g-specific adenine glycosylase
SaSA30_RS07875	COG3118	belongs to the thioredoxin family
SaSA30_RS07900	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA30_RS07905	COG0681	Belongs to the peptidase S26 family
SaSA30_RS07910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA30_RS07925	COG1882	Formate acetyltransferase
SaSA30_RS07930	COG3576	pyridoxamine 5-phosphate
SaSA30_RS07935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA30_RS07950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_RS07960	COG2814	Major facilitator Superfamily
SaSA30_RS07965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA30_RS07985	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA30_RS07990	COG4988	ABC transporter
SaSA30_RS07995	COG1294	oxidase, subunit
SaSA30_RS08000	COG1271	oxidase subunit
SaSA30_RS08005	COG1252	NADH dehydrogenase
SaSA30_RS08030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA30_RS08035	COG0789	Transcriptional regulator
SaSA30_RS08085	COG1214	PFAM Peptidase M22, glycoprotease
SaSA30_RS08100	COG3942	CHAP domain
SaSA30_RS08105	COG0174	glutamine synthetase
SaSA30_RS08110	COG0789	Transcriptional regulator
SaSA30_RS08125	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA30_RS08155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA30_RS08180	COG1162	GTPase activity
SaSA30_RS08200	COG0693	protein deglycase activity
SaSA30_RS08240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA30_RS08245	COG1696	Membrane protein involved in D-alanine export
SaSA30_RS08275	COG3314	Sporulation integral membrane protein YlbJ
SaSA30_RS08285	COG4175	Glycine betaine
SaSA30_RS08285	COG3448	diguanylate cyclase activity
SaSA30_RS08325	COG3775	system Galactitol-specific IIC component
SaSA30_RS08330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_RS08340	COG1609	Transcriptional regulator
SaSA30_RS08390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA30_RS08425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA30_RS08430	COG1428	Deoxynucleoside kinase
SaSA30_RS08440	COG0542	response to heat
SaSA30_RS08445	COG4463	regulation of RNA biosynthetic process
SaSA30_RS08455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA30_RS08465	COG0450	alkyl hydroperoxide reductase
SaSA30_RS08480	COG0025	NhaP-type Na H and K H
SaSA30_RS08490	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA30_RS08495	COG3590	peptidase
SaSA30_RS08525	COG1609	Transcriptional regulator
SaSA30_RS08535	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_RS08540	COG3715	PTS system
SaSA30_RS08545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_RS08550	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA30_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_RS08605	COG2176	DNA-directed DNA polymerase activity
SaSA30_RS08625	COG4589	Belongs to the CDS family
SaSA30_RS08635	COG1862	Preprotein translocase
SaSA30_RS08660	COG4565	transcriptional regulatory protein
SaSA30_RS08665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA30_RS08675	COG3842	ATPase activity
SaSA30_RS08745	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA30_RS08765	COG1363	Peptidase, m42
SaSA30_RS08780	COG2207	Transcriptional regulator
SaSA30_RS08780	COG4753	response regulator
SaSA30_RS08785	COG2972	Histidine kinase
SaSA30_RS08790	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_RS08795	COG3715	PTS system
SaSA30_RS08825	COG1131	(ABC) transporter
SaSA30_RS08845	COG3290	protein histidine kinase activity
SaSA30_RS08865	COG2190	(PTS) system
SaSA30_RS08865	COG1263	PTS System
SaSA30_RS08865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_RS08870	COG5002	protein histidine kinase activity
SaSA30_RS08885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA30_RS08890	COG0581	inorganic phosphate transmembrane transporter activity
SaSA30_RS08910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA30_RS08925	COG0789	Transcriptional regulator
SaSA30_RS08960	COG0456	acetyltransferase
SaSA30_RS08965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA30_RS09050	COG1396	sequence-specific DNA binding
SaSA30_RS09070	COG2897	thiosulfate sulfurtransferase activity
SaSA30_RS09085	COG0371	Dehydrogenase
SaSA30_RS09110	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA30_RS09140	COG0495	leucyl-tRNA aminoacylation
SaSA30_RS09145	COG2814	Major facilitator Superfamily
SaSA30_RS09150	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA30_RS09175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_RS09180	COG0564	pseudouridine synthase activity
SaSA30_RS09200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA30_RS09205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA30_RS09225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA30_RS09230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA30_RS09230	COG1116	anion transmembrane transporter activity
SaSA30_RS09240	COG0561	phosphatase activity
SaSA30_RS09245	COG2514	catechol 2,3-dioxygenase activity
SaSA30_RS09250	COG3022	response to hydroperoxide
SaSA30_RS09255	COG0602	queuosine metabolic process
SaSA30_RS09275	COG1328	CTP reductase activity
SaSA30_RS09295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA30_RS09305	COG1393	Belongs to the ArsC family
SaSA30_RS09310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA30_RS09315	COG1546	Belongs to the CinA family
SaSA30_RS09315	COG1058	Belongs to the CinA family
SaSA30_RS09360	COG0018	arginyl-trna synthetase
SaSA30_RS09370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA30_RS09375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA30_RS09385	COG0124	histidyl-tRNA synthetase
SaSA30_RS09395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA30_RS09410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA30_RS09420	COG0784	Response regulator, receiver
SaSA30_RS09425	COG0517	IMP dehydrogenase activity
SaSA30_RS09425	COG1125	glycine betaine transport
SaSA30_RS09430	COG1174	glycine betaine transport
SaSA30_RS09435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA30_RS09435	COG0392	lysyltransferase activity
SaSA30_RS09445	COG3759	membrane
SaSA30_RS09475	COG0305	Participates in initiation and elongation during chromosome replication
SaSA30_RS09500	COG0482	sulfurtransferase activity
SaSA30_RS09505	COG1760	l-serine dehydratase
SaSA30_RS09510	COG1760	l-serine dehydratase
SaSA30_RS09515	COG0741	lytic transglycosylase activity
SaSA30_RS09540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA30_RS09550	COG0612	Peptidase, M16
SaSA30_RS09555	COG2501	S4 domain
SaSA30_RS09575	COG0517	IMP dehydrogenase activity
SaSA30_RS09575	COG0516	GMP reductase activity
SaSA30_RS09605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA30_RS09615	COG0549	Belongs to the carbamate kinase family
SaSA30_RS09635	COG0488	(ABC) transporter
SaSA30_RS09640	COG4485	Bacterial membrane protein, YfhO
SaSA30_RS09660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA30_RS09670	COG1475	DNA binding