locus-tag	class	description
SaSA33_RS00030	COG0012	GTP binding
SaSA33_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA33_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA33_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA33_RS00230	COG1695	Transcriptional regulator
SaSA33_RS00245	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA33_RS00280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA33_RS00315	COG1131	(ABC) transporter
SaSA33_RS00325	COG2190	(PTS) system
SaSA33_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA33_RS00325	COG1263	PTS System
SaSA33_RS00330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA33_RS00335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA33_RS00340	COG0275	rRNA processing
SaSA33_RS00350	COG0768	penicillin binding
SaSA33_RS00360	COG0513	Belongs to the DEAD box helicase family
SaSA33_RS00375	COG1126	abc transporter atp-binding protein
SaSA33_RS00385	COG0492	ferredoxin-NADP+ reductase activity
SaSA33_RS00390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA33_RS00405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA33_RS00435	COG0116	Belongs to the methyltransferase superfamily
SaSA33_RS00445	COG1854	S-ribosylhomocysteine lyase activity
SaSA33_RS00450	COG1418	mRNA catabolic process
SaSA33_RS00450	COG4372	Transposase
SaSA33_RS00460	COG1131	(ABC) transporter
SaSA33_RS00490	COG0194	GDP metabolic process
SaSA33_RS00500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA33_RS00505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA33_RS00510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA33_RS00510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA33_RS00520	COG0515	serine threonine protein kinase
SaSA33_RS00520	COG2815	serine threonine protein kinase
SaSA33_RS00530	COG4585	Histidine kinase
SaSA33_RS00535	COG2197	response regulator
SaSA33_RS00545	COG1098	S1 RNA binding domain
SaSA33_RS00555	COG1349	DNA-binding transcription factor activity
SaSA33_RS00565	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA33_RS00585	COG1739	Uncharacterized protein family UPF0029
SaSA33_RS00590	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaSA33_RS00595	COG1040	competence protein
SaSA33_RS00630	COG0527	aspartate kinase activity
SaSA33_RS00635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA33_RS00645	COG1024	Enoyl-CoA hydratase
SaSA33_RS00655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA33_RS00665	COG2070	2-Nitropropane dioxygenase
SaSA33_RS00670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA33_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA33_RS00680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA33_RS00715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SaSA33_RS00730	COG3716	PTS system mannose fructose sorbose family IID component
SaSA33_RS00735	COG3715	PTS system
SaSA33_RS00765	COG2252	PERMEase
SaSA33_RS00770	COG0802	atpase or kinase
SaSA33_RS00780	COG1316	TRANSCRIPTIONal
SaSA33_RS00790	COG0537	adenosine 5'-monophosphoramidase activity
SaSA33_RS00805	COG1131	(ABC) transporter
SaSA33_RS00810	COG4473	ABC transporter
SaSA33_RS00820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA33_RS00835	COG0195	Participates in both transcription termination and antitermination
SaSA33_RS00840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA33_RS00850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA33_RS00855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA33_RS00880	COG2860	membrane
SaSA33_RS00890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA33_RS00890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA33_RS00895	COG1832	CoA-binding protein
SaSA33_RS00930	COG1268	BioY protein
SaSA33_RS00935	COG1234	tRNA 3'-trailer cleavage
SaSA33_RS00950	COG0166	Belongs to the GPI family
SaSA33_RS00955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA33_RS00960	COG0457	Tetratricopeptide repeat
SaSA33_RS00960	COG0705	Rhomboid family
SaSA33_RS00965	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA33_RS00970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA33_RS00985	COG0706	membrane insertase activity
SaSA33_RS01090	COG0436	Aminotransferase
SaSA33_RS01115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA33_RS01120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA33_RS01125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA33_RS01140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA33_RS01180	COG0395	ABC-type sugar transport system, permease component
SaSA33_RS01195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA33_RS01205	COG3458	cephalosporin-C deacetylase activity
SaSA33_RS01210	COG1737	Transcriptional regulator
SaSA33_RS01220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA33_RS01240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA33_RS01255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA33_RS01265	COG2755	lipolytic protein G-D-S-L family
SaSA33_RS01265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA33_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
SaSA33_RS01270	COG1454	alcohol dehydrogenase
SaSA33_RS01275	COG1064	alcohol dehydrogenase
SaSA33_RS01285	COG0534	Mate efflux family protein
SaSA33_RS01395	COG0201	protein transport
SaSA33_RS01400	COG0563	adenylate kinase activity
SaSA33_RS01425	COG0202	RNA polymerase activity
SaSA33_RS01475	COG1121	(ABC) transporter
SaSA33_RS01480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA33_RS01490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA33_RS01495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA33_RS01495	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA33_RS01520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA33_RS01525	COG1459	type II secretion system
SaSA33_RS01575	COG1363	Peptidase, m42
SaSA33_RS01590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA33_RS01595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA33_RS01610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA33_RS01630	COG1346	cytolysis
SaSA33_RS01640	COG0601	transmembrane transport
SaSA33_RS01645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA33_RS01650	COG1122	ATPase activity
SaSA33_RS01665	COG0366	Alpha amylase catalytic
SaSA33_RS01670	COG0366	Alpha amylase catalytic
SaSA33_RS01685	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA33_RS01715	COG1045	serine acetyltransferase
SaSA33_RS01725	COG0215	cysteine-tRNA ligase activity
SaSA33_RS01730	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA33_RS01755	COG1476	TRANSCRIPTIONal
SaSA33_RS01760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA33_RS01815	COG1396	sequence-specific DNA binding
SaSA33_RS01830	COG1732	Glycine betaine
SaSA33_RS01960	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA33_RS01975	COG0443	Heat shock 70 kDa protein
SaSA33_RS01985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA33_RS01995	COG0351	phosphomethylpyrimidine kinase
SaSA33_RS02000	COG4720	Psort location CytoplasmicMembrane, score
SaSA33_RS02010	COG0668	transmembrane transport
SaSA33_RS02040	COG0756	dUTP diphosphatase activity
SaSA33_RS02070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA33_RS02075	COG1879	ABC-type sugar transport system periplasmic component
SaSA33_RS02080	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA33_RS02095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA33_RS02100	COG1609	Transcriptional regulator
SaSA33_RS02110	COG0577	efflux transmembrane transporter activity
SaSA33_RS02115	COG1136	(ABC) transporter
SaSA33_RS02140	COG0191	fructose-bisphosphate aldolase activity
SaSA33_RS02160	COG1461	Dihydroxyacetone kinase
SaSA33_RS02180	COG1126	abc transporter atp-binding protein
SaSA33_RS02185	COG0765	amino acid transport
SaSA33_RS02205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA33_RS02215	COG0719	Fe-S assembly protein
SaSA33_RS02230	COG0719	Fe-S assembly protein
SaSA33_RS02235	COG1686	Belongs to the peptidase S11 family
SaSA33_RS02240	COG1686	Belongs to the peptidase S11 family
SaSA33_RS02245	COG4166	transmembrane transport
SaSA33_RS02250	COG0601	transmembrane transport
SaSA33_RS02255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA33_RS02260	COG0444	Belongs to the ABC transporter superfamily
SaSA33_RS02265	COG4608	Belongs to the ABC transporter superfamily
SaSA33_RS02315	COG2137	regulation of response to DNA damage stimulus
SaSA33_RS02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA33_RS02330	COG2153	protein acetylation
SaSA33_RS02340	COG1442	glycosyl transferase family 8
SaSA33_RS02340	COG1216	Glycosyl transferase, family 2
SaSA33_RS02400	COG0789	Transcriptional regulator
SaSA33_RS02405	COG1063	alcohol dehydrogenase
SaSA33_RS02410	COG0656	L-ascorbic acid biosynthetic process
SaSA33_RS02450	COG2226	methyltransferase
SaSA33_RS02460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA33_RS02465	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA33_RS02470	COG3775	system Galactitol-specific IIC component
SaSA33_RS02475	COG0235	Class ii aldolase
SaSA33_RS02490	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA33_RS02495	COG2207	Transcriptional regulator
SaSA33_RS02505	COG1175	transmembrane transport
SaSA33_RS02510	COG0395	ABC-type sugar transport system, permease component
SaSA33_RS02530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA33_RS02600	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA33_RS02615	COG2315	Protein conserved in bacteria
SaSA33_RS02630	COG0742	ribosomal rna small subunit methyltransferase
SaSA33_RS02645	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA33_RS02655	COG4470	Protein conserved in bacteria
SaSA33_RS02675	COG1132	(ABC) transporter
SaSA33_RS02680	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA33_RS02685	COG1268	BioY protein
SaSA33_RS02690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA33_RS02710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA33_RS02735	COG1217	gtp-binding protein TYPA
SaSA33_RS02770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA33_RS02780	COG0762	integral membrane protein
SaSA33_RS02785	COG2302	S4 RNA-binding domain
SaSA33_RS02790	COG3599	regulation of cell shape
SaSA33_RS02810	COG0542	response to heat
SaSA33_RS02820	COG4703	Protein of unknown function (DUF1797)
SaSA33_RS02825	COG0765	amino acid transport
SaSA33_RS02830	COG1126	abc transporter atp-binding protein
SaSA33_RS02835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA33_RS02845	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA33_RS02850	COG1570	exodeoxyribonuclease VII activity
SaSA33_RS02855	COG1722	exodeoxyribonuclease VII activity
SaSA33_RS02865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA33_RS02870	COG1438	arginine binding
SaSA33_RS02875	COG0497	DNA recombination
SaSA33_RS02880	COG1307	EDD domain protein, DegV family
SaSA33_RS02930	COG1078	dGTPase activity
SaSA33_RS02955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA33_RS02965	COG2884	Cell division ATP-binding protein ftsE
SaSA33_RS02970	COG2177	Part of the ABC transporter FtsEX involved in
SaSA33_RS02990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA33_RS02990	COG1199	ATP-dependent helicase activity
SaSA33_RS02995	COG0436	Aminotransferase
SaSA33_RS03000	COG0017	Asparaginyl-tRNA synthetase
SaSA33_RS03025	COG1660	Displays ATPase and GTPase activities
SaSA33_RS03050	COG0254	rRNA binding
SaSA33_RS03055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA33_RS03060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA33_RS03065	COG0716	FMN binding
SaSA33_RS03070	COG1605	Chorismate mutase
SaSA33_RS03070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA33_RS03080	COG0335	large ribosomal subunit rRNA binding
SaSA33_RS03090	COG0772	Belongs to the SEDS family
SaSA33_RS03110	COG0560	Phosphoserine phosphatase
SaSA33_RS03125	COG0148	phosphopyruvate hydratase activity
SaSA33_RS03240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA33_RS03290	COG3590	peptidase
SaSA33_RS03335	COG1136	(ABC) transporter
SaSA33_RS03350	COG0586	Pfam SNARE associated Golgi protein
SaSA33_RS03355	COG4619	ABC transporter
SaSA33_RS03360	COG0390	transport system, permease component
SaSA33_RS03370	COG0583	DNA-binding transcription factor activity
SaSA33_RS03380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA33_RS03385	COG2211	Major facilitator Superfamily
SaSA33_RS03390	COG3250	beta-galactosidase activity
SaSA33_RS03395	COG2186	Transcriptional regulator
SaSA33_RS03415	COG1609	Transcriptional regulator
SaSA33_RS03430	COG0438	transferase activity, transferring glycosyl groups
SaSA33_RS03455	COG0765	amino acid transport
SaSA33_RS03460	COG0765	amino acid transport
SaSA33_RS03465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA33_RS03470	COG1126	abc transporter atp-binding protein
SaSA33_RS03475	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS03480	COG5002	protein histidine kinase activity
SaSA33_RS03485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA33_RS03490	COG2832	Protein of unknown function (DUF454)
SaSA33_RS03500	COG1196	nuclear chromosome segregation
SaSA33_RS03505	COG0561	phosphatase activity
SaSA33_RS03510	COG0561	phosphatase activity
SaSA33_RS03515	COG0552	protein localization to endoplasmic reticulum
SaSA33_RS03530	COG3689	TIGRFAM TIGR03943 family protein
SaSA33_RS03535	COG0701	Predicted permease
SaSA33_RS03550	COG2183	response to ionizing radiation
SaSA33_RS03555	COG3091	SprT-like family
SaSA33_RS03560	COG1983	PspC domain protein
SaSA33_RS03600	COG0826	peptidase U32
SaSA33_RS03605	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA33_RS03615	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA33_RS03630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA33_RS03630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA33_RS03655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA33_RS03690	COG0772	Belongs to the SEDS family
SaSA33_RS03710	COG0768	penicillin binding
SaSA33_RS03725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA33_RS03755	COG2011	ABC-type metal ion transport system permease component
SaSA33_RS03760	COG1464	Belongs to the NlpA lipoprotein family
SaSA33_RS03765	COG0513	Belongs to the DEAD box helicase family
SaSA33_RS03775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA33_RS03785	COG1596	polysaccharide export
SaSA33_RS03785	COG1555	photosystem II stabilization
SaSA33_RS03805	COG1609	Transcriptional regulator
SaSA33_RS03810	COG0657	acetylesterase activity
SaSA33_RS03815	COG2264	protein methyltransferase activity
SaSA33_RS03825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA33_RS03830	COG3711	transcriptional antiterminator
SaSA33_RS03850	COG3835	regulator
SaSA33_RS03855	COG1929	Belongs to the glycerate kinase type-1 family
SaSA33_RS03860	COG2610	gluconate transmembrane transporter activity
SaSA33_RS03875	COG1846	Transcriptional regulator
SaSA33_RS03880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA33_RS03895	COG0435	Glutathione S-transferase
SaSA33_RS03900	COG1187	pseudouridine synthase activity
SaSA33_RS03925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA33_RS03930	COG4122	O-methyltransferase activity
SaSA33_RS03940	COG4894	glucomannan catabolic process
SaSA33_RS03945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA33_RS03950	COG1811	Na channel or pump
SaSA33_RS03955	COG1442	glycosyl transferase family 8
SaSA33_RS03970	COG1476	TRANSCRIPTIONal
SaSA33_RS03985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA33_RS03990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA33_RS03995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA33_RS04010	COG1012	belongs to the aldehyde dehydrogenase family
SaSA33_RS04015	COG0726	polysaccharide deacetylase
SaSA33_RS04025	COG0513	Belongs to the DEAD box helicase family
SaSA33_RS04035	COG1956	GAF domain-containing protein
SaSA33_RS04040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA33_RS04050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SaSA33_RS04050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SaSA33_RS04055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA33_RS04085	COG4721	ABC-type cobalt transport system, permease component
SaSA33_RS04090	COG1122	ATPase activity
SaSA33_RS04100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA33_RS04110	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA33_RS04115	COG0352	thiamine-phosphate diphosphorylase activity
SaSA33_RS04120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA33_RS04130	COG4109	DRTGG domain
SaSA33_RS04135	COG0024	Methionine aminopeptidase
SaSA33_RS04150	COG4708	membrane
SaSA33_RS04155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA33_RS04160	COG1597	lipid kinase activity
SaSA33_RS04165	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA33_RS04195	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA33_RS04235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA33_RS04260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA33_RS04260	COG0072	phenylalanine-tRNA ligase activity
SaSA33_RS04265	COG2321	neutral zinc metallopeptidase
SaSA33_RS04275	COG1074	ATP-dependent DNA helicase activity
SaSA33_RS04285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA33_RS04290	COG0488	(ABC) transporter
SaSA33_RS04295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA33_RS04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA33_RS04300	COG0022	dehydrogenase e1 component
SaSA33_RS04315	COG0095	Lipoate-protein ligase
SaSA33_RS04320	COG3442	glutamine amidotransferase
SaSA33_RS04325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA33_RS04330	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA33_RS04355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA33_RS04375	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA33_RS04380	COG1518	maintenance of DNA repeat elements
SaSA33_RS04385	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA33_RS04405	COG0481	GTPase activity
SaSA33_RS04415	COG1418	mRNA catabolic process
SaSA33_RS04450	COG0398	Pfam SNARE associated Golgi protein
SaSA33_RS04460	COG1131	(ABC) transporter
SaSA33_RS04465	COG1725	Transcriptional regulator
SaSA33_RS04475	COG0205	6-phosphofructokinase activity
SaSA33_RS04480	COG0469	pyruvate kinase activity
SaSA33_RS04485	COG0681	Belongs to the peptidase S26 family
SaSA33_RS04495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA33_RS04500	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA33_RS04505	COG0765	amino acid transport
SaSA33_RS04510	COG1126	abc transporter atp-binding protein
SaSA33_RS04530	COG1072	(Pantothenic acid kinase))
SaSA33_RS04540	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA33_RS04555	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA33_RS04575	COG3764	Sortase (surface protein transpeptidase)
SaSA33_RS04580	COG0346	lactoylglutathione lyase activity
SaSA33_RS04600	COG2188	Transcriptional regulator
SaSA33_RS04605	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA33_RS04615	COG1464	Belongs to the NlpA lipoprotein family
SaSA33_RS04640	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS04645	COG5002	protein histidine kinase activity
SaSA33_RS04650	COG4974	Belongs to the 'phage' integrase family
SaSA33_RS04670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA33_RS04675	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SaSA33_RS04680	COG5002	protein histidine kinase activity
SaSA33_RS04685	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS04695	COG0704	Plays a role in the regulation of phosphate uptake
SaSA33_RS04700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA33_RS04705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA33_RS04710	COG0581	inorganic phosphate transmembrane transporter activity
SaSA33_RS04715	COG0573	inorganic phosphate transmembrane transporter activity
SaSA33_RS04735	COG4476	Belongs to the UPF0223 family
SaSA33_RS04745	COG0196	riboflavin kinase activity
SaSA33_RS04780	COG1136	(ABC) transporter
SaSA33_RS04785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA33_RS04790	COG0758	DNA mediated transformation
SaSA33_RS04795	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA33_RS04800	COG4604	ABC transporter, ATP-binding protein
SaSA33_RS04805	COG4605	iron ion homeostasis
SaSA33_RS04810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA33_RS04815	COG0110	maltose O-acetyltransferase activity
SaSA33_RS04825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA33_RS04830	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA33_RS04835	COG1966	Carbon starvation protein
SaSA33_RS04840	COG3279	Response regulator of the LytR AlgR family
SaSA33_RS04845	COG3275	phosphorelay sensor kinase activity
SaSA33_RS04890	COG0505	Belongs to the CarA family
SaSA33_RS04905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA33_RS04920	COG0488	(ABC) transporter
SaSA33_RS04930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA33_RS04945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA33_RS04995	COG0095	Lipoate-protein ligase
SaSA33_RS05005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA33_RS05010	COG4684	Psort location CytoplasmicMembrane, score
SaSA33_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA33_RS05060	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA33_RS05075	COG1942	4-Oxalocrotonate Tautomerase
SaSA33_RS05095	COG1053	succinate dehydrogenase
SaSA33_RS05095	COG3976	FMN-binding domain protein
SaSA33_RS05095	COG0431	NADPH-dependent FMN reductase
SaSA33_RS05105	COG2233	PERMEase
SaSA33_RS05140	COG0564	pseudouridine synthase activity
SaSA33_RS05145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA33_RS05150	COG2357	RelA SpoT domain protein
SaSA33_RS05165	COG1104	cysteine desulfurase activity
SaSA33_RS05185	COG0628	permease
SaSA33_RS05200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA33_RS05245	COG0561	phosphatase activity
SaSA33_RS05270	COG1177	transmembrane transport
SaSA33_RS05275	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA33_RS05285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA33_RS05290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA33_RS05310	COG0285	dihydrofolate synthase activity
SaSA33_RS05315	COG2962	Rard protein
SaSA33_RS05330	COG0726	polysaccharide deacetylase
SaSA33_RS05335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA33_RS05430	COG2261	transglycosylase associated protein
SaSA33_RS05455	COG1115	amino acid carrier protein
SaSA33_RS05460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA33_RS05470	COG1346	cytolysis
SaSA33_RS05485	COG0539	negative regulation of cytoplasmic translation
SaSA33_RS05505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA33_RS05515	COG0187	DNA topoisomerase II activity
SaSA33_RS05520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA33_RS05525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA33_RS05535	COG2755	lipolytic protein G-D-S-L family
SaSA33_RS05535	COG1083	cytidylyl-transferase
SaSA33_RS05550	COG2089	acid synthase
SaSA33_RS05570	COG1216	Glycosyl transferase, family 2
SaSA33_RS05570	COG1442	glycosyl transferase family 8
SaSA33_RS05585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA33_RS05590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA33_RS05610	COG1316	TRANSCRIPTIONal
SaSA33_RS05660	COG3842	ATPase activity
SaSA33_RS05675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaSA33_RS05680	COG3527	Alpha-acetolactate decarboxylase
SaSA33_RS05685	COG0028	Belongs to the TPP enzyme family
SaSA33_RS05690	COG0457	Tetratricopeptide repeat
SaSA33_RS05705	COG1051	belongs to the nudix hydrolase family
SaSA33_RS05715	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA33_RS05725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA33_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA33_RS05740	COG2384	SAM-dependent methyltransferase
SaSA33_RS05770	COG0300	oxidoreductase activity
SaSA33_RS05785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaSA33_RS05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA33_RS05815	COG1573	uracil-dna glycosylase
SaSA33_RS05820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA33_RS05830	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA33_RS05845	COG0534	Mate efflux family protein
SaSA33_RS05900	COG0833	amino acid
SaSA33_RS05940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA33_RS05950	COG3425	synthase
SaSA33_RS05965	COG1272	protein, Hemolysin III
SaSA33_RS06010	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS06030	COG1132	(ABC) transporter
SaSA33_RS06045	COG0488	(ABC) transporter
SaSA33_RS06075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA33_RS06075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA33_RS06075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA33_RS06080	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA33_RS06085	COG1349	DNA-binding transcription factor activity
SaSA33_RS06145	COG1837	Belongs to the UPF0109 family
SaSA33_RS06150	COG0228	four-way junction DNA binding
SaSA33_RS06155	COG0577	efflux transmembrane transporter activity
SaSA33_RS06160	COG1136	(ABC) transporter
SaSA33_RS06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA33_RS06175	COG0505	Belongs to the CarA family
SaSA33_RS06185	COG0564	pseudouridine synthase activity
SaSA33_RS06195	COG0583	DNA-binding transcription factor activity
SaSA33_RS06200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA33_RS06220	COG0301	tRNA thio-modification
SaSA33_RS06225	COG1104	cysteine desulfurase activity
SaSA33_RS06235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA33_RS06260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaSA33_RS06265	COG1368	sulfuric ester hydrolase activity
SaSA33_RS06275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA33_RS06285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA33_RS06315	COG2244	polysaccharide biosynthetic process
SaSA33_RS06320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA33_RS06325	COG1120	ATPase activity
SaSA33_RS06360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA33_RS06365	COG1253	flavin adenine dinucleotide binding
SaSA33_RS06370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA33_RS06375	COG1242	4 iron, 4 sulfur cluster binding
SaSA33_RS06380	COG0671	phosphoesterase, PA-phosphatase related
SaSA33_RS06385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA33_RS06430	COG0297	glycogen (starch) synthase activity
SaSA33_RS06485	COG0463	Glycosyl transferase, family 2
SaSA33_RS06490	COG1215	transferase activity, transferring glycosyl groups
SaSA33_RS06500	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA33_RS06505	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA33_RS06510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA33_RS06515	COG0358	DNA primase activity
SaSA33_RS06520	COG1970	mechanosensitive ion channel activity
SaSA33_RS06535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA33_RS06540	COG0004	ammonium transporteR
SaSA33_RS06550	COG1054	Belongs to the UPF0176 family
SaSA33_RS06560	COG2271	Major facilitator Superfamily
SaSA33_RS06570	COG0058	SHG alpha-glucan phosphorylase activity
SaSA33_RS06575	COG1640	4-alpha-glucanotransferase
SaSA33_RS06580	COG1609	Transcriptional regulator
SaSA33_RS06590	COG1175	transmembrane transport
SaSA33_RS06595	COG3833	ABC-type maltose transport systems, permease component
SaSA33_RS06630	COG0438	transferase activity, transferring glycosyl groups
SaSA33_RS06685	COG0765	amino acid transport
SaSA33_RS06690	COG1126	abc transporter atp-binding protein
SaSA33_RS06715	COG2309	aminopeptidase activity
SaSA33_RS06730	COG1187	pseudouridine synthase activity
SaSA33_RS06735	COG0656	L-ascorbic acid biosynthetic process
SaSA33_RS06740	COG0778	Nitroreductase
SaSA33_RS06745	COG0346	lactoylglutathione lyase activity
SaSA33_RS06755	COG1113	amino acid transport
SaSA33_RS06760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SaSA33_RS06790	COG1131	(ABC) transporter
SaSA33_RS06800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA33_RS06860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SaSA33_RS06895	COG1702	phosphate starvation-inducible protein PhoH
SaSA33_RS06920	COG0233	cytoplasmic translational termination
SaSA33_RS06935	COG0444	Belongs to the ABC transporter superfamily
SaSA33_RS06940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA33_RS06945	COG0601	transmembrane transport
SaSA33_RS06950	COG0747	negative chemotaxis
SaSA33_RS06955	COG0081	regulation of translation
SaSA33_RS06960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA33_RS06970	COG1473	amidohydrolase
SaSA33_RS06975	COG0583	DNA-binding transcription factor activity
SaSA33_RS06990	COG1674	ftsk spoiiie
SaSA33_RS06995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA33_RS07020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA33_RS07055	COG0673	inositol 2-dehydrogenase activity
SaSA33_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA33_RS07120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA33_RS07120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA33_RS07140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA33_RS07150	COG0708	Exodeoxyribonuclease III
SaSA33_RS07155	COG1393	Belongs to the ArsC family
SaSA33_RS07160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA33_RS07165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA33_RS07175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA33_RS07200	COG0470	DNA polymerase III
SaSA33_RS07210	COG0517	IMP dehydrogenase activity
SaSA33_RS07230	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA33_RS07250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA33_RS07255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA33_RS07265	COG0531	amino acid
SaSA33_RS07290	COG1187	pseudouridine synthase activity
SaSA33_RS07325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA33_RS07340	COG1827	regulation of RNA biosynthetic process
SaSA33_RS07355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA33_RS07360	COG1254	Belongs to the acylphosphatase family
SaSA33_RS07370	COG0765	amino acid transport
SaSA33_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA33_RS07390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA33_RS07415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA33_RS07425	COG1484	DNA-dependent DNA replication
SaSA33_RS07440	COG5002	protein histidine kinase activity
SaSA33_RS07445	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS07455	COG0501	Belongs to the peptidase M48B family
SaSA33_RS07460	COG1704	LemA family
SaSA33_RS07465	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA33_RS07470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA33_RS07475	COG0569	domain protein
SaSA33_RS07505	COG1114	Component of the transport system for branched-chain amino acids
SaSA33_RS07510	COG1063	alcohol dehydrogenase
SaSA33_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA33_RS07540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA33_RS07550	COG0217	transcriptional regulatory protein
SaSA33_RS07560	COG2376	Dihydroxyacetone kinase
SaSA33_RS07565	COG1309	transcriptional regulator
SaSA33_RS07575	COG2376	Dihydroxyacetone kinase
SaSA33_RS07580	COG1461	Dihydroxyacetone kinase
SaSA33_RS07585	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA33_RS07590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA33_RS07600	COG0789	Transcriptional regulator
SaSA33_RS07605	COG1323	Belongs to the UPF0348 family
SaSA33_RS07615	COG2226	methyltransferase
SaSA33_RS07620	COG0799	negative regulation of ribosome biogenesis
SaSA33_RS07630	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA33_RS07635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA33_RS07640	COG1534	Rna-binding protein
SaSA33_RS07645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA33_RS07650	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaSA33_RS07665	COG0154	amidase activity
SaSA33_RS07670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA33_RS07675	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA33_RS07675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA33_RS07685	COG0517	IMP dehydrogenase activity
SaSA33_RS07695	COG1335	isochorismatase
SaSA33_RS07700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA33_RS07705	COG0436	Aminotransferase
SaSA33_RS07710	COG0589	response to stress
SaSA33_RS07720	COG0252	asparaginase activity
SaSA33_RS07730	COG4989	oxidoreductase activity
SaSA33_RS07735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA33_RS07750	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA33_RS07755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SaSA33_RS07770	COG1940	carbohydrate kinase activity
SaSA33_RS07775	COG2190	(PTS) system
SaSA33_RS07775	COG1263	PTS System
SaSA33_RS07775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA33_RS07780	COG1621	beta-fructofuranosidase activity
SaSA33_RS07785	COG1609	Transcriptional regulator
SaSA33_RS07790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA33_RS07800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA33_RS07830	COG2131	deaminase
SaSA33_RS07835	COG0006	proline dipeptidase activity
SaSA33_RS07870	COG0629	single-stranded DNA binding
SaSA33_RS07875	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA33_RS07880	COG1194	a g-specific adenine glycosylase
SaSA33_RS07890	COG3118	belongs to the thioredoxin family
SaSA33_RS07915	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA33_RS07920	COG0681	Belongs to the peptidase S26 family
SaSA33_RS07940	COG1882	Formate acetyltransferase
SaSA33_RS07945	COG3576	pyridoxamine 5-phosphate
SaSA33_RS07950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA33_RS07965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA33_RS07975	COG2814	Major facilitator Superfamily
SaSA33_RS07980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA33_RS08000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA33_RS08005	COG4988	ABC transporter
SaSA33_RS08010	COG1294	oxidase, subunit
SaSA33_RS08015	COG1271	oxidase subunit
SaSA33_RS08020	COG1252	NADH dehydrogenase
SaSA33_RS08045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA33_RS08050	COG0789	Transcriptional regulator
SaSA33_RS08065	COG2081	HI0933 family
SaSA33_RS08095	COG0456	acetyltransferase
SaSA33_RS08100	COG1214	PFAM Peptidase M22, glycoprotease
SaSA33_RS08115	COG3942	CHAP domain
SaSA33_RS08120	COG0174	glutamine synthetase
SaSA33_RS08125	COG0789	Transcriptional regulator
SaSA33_RS08140	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA33_RS08170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA33_RS08195	COG1162	GTPase activity
SaSA33_RS08215	COG0693	protein deglycase activity
SaSA33_RS08250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA33_RS08255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA33_RS08260	COG1696	Membrane protein involved in D-alanine export
SaSA33_RS08290	COG3314	Sporulation integral membrane protein YlbJ
SaSA33_RS08300	COG4175	Glycine betaine
SaSA33_RS08300	COG3448	diguanylate cyclase activity
SaSA33_RS08340	COG3775	system Galactitol-specific IIC component
SaSA33_RS08345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA33_RS08355	COG1609	Transcriptional regulator
SaSA33_RS08405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA33_RS08440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA33_RS08445	COG1428	Deoxynucleoside kinase
SaSA33_RS08455	COG0542	response to heat
SaSA33_RS08460	COG4463	regulation of RNA biosynthetic process
SaSA33_RS08470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA33_RS08480	COG0450	alkyl hydroperoxide reductase
SaSA33_RS08495	COG0025	NhaP-type Na H and K H
SaSA33_RS08505	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA33_RS08510	COG3590	peptidase
SaSA33_RS08540	COG1609	Transcriptional regulator
SaSA33_RS08550	COG3716	PTS system mannose fructose sorbose family IID component
SaSA33_RS08555	COG3715	PTS system
SaSA33_RS08560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA33_RS08565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA33_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA33_RS08615	COG1846	Transcriptional regulator
SaSA33_RS08620	COG2176	DNA-directed DNA polymerase activity
SaSA33_RS08625	COG1388	LysM domain
SaSA33_RS08625	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA33_RS08645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SaSA33_RS08650	COG1862	Preprotein translocase
SaSA33_RS08670	COG3290	protein histidine kinase activity
SaSA33_RS08675	COG4565	transcriptional regulatory protein
SaSA33_RS08680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA33_RS08690	COG3842	ATPase activity
SaSA33_RS08760	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA33_RS08780	COG1363	Peptidase, m42
SaSA33_RS08795	COG2207	Transcriptional regulator
SaSA33_RS08795	COG4753	response regulator
SaSA33_RS08800	COG2972	Histidine kinase
SaSA33_RS08805	COG3716	PTS system mannose fructose sorbose family IID component
SaSA33_RS08810	COG3715	PTS system
SaSA33_RS08840	COG1131	(ABC) transporter
SaSA33_RS08860	COG3290	protein histidine kinase activity
SaSA33_RS08880	COG1263	PTS System
SaSA33_RS08880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA33_RS08880	COG2190	(PTS) system
SaSA33_RS08885	COG5002	protein histidine kinase activity
SaSA33_RS08900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA33_RS08905	COG0581	inorganic phosphate transmembrane transporter activity
SaSA33_RS08925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA33_RS08940	COG0789	Transcriptional regulator
SaSA33_RS08975	COG0456	acetyltransferase
SaSA33_RS08980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA33_RS09050	COG1131	(ABC) transporter
SaSA33_RS09060	COG1396	sequence-specific DNA binding
SaSA33_RS09080	COG2897	thiosulfate sulfurtransferase activity
SaSA33_RS09095	COG0371	Dehydrogenase
SaSA33_RS09120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA33_RS09135	COG0745	RESPONSE REGULATOR receiver
SaSA33_RS09150	COG0495	leucyl-tRNA aminoacylation
SaSA33_RS09155	COG2814	Major facilitator Superfamily
SaSA33_RS09160	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA33_RS09185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA33_RS09190	COG0564	pseudouridine synthase activity
SaSA33_RS09210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA33_RS09215	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA33_RS09235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA33_RS09240	COG1116	anion transmembrane transporter activity
SaSA33_RS09240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA33_RS09250	COG0561	phosphatase activity
SaSA33_RS09255	COG2514	catechol 2,3-dioxygenase activity
SaSA33_RS09265	COG0602	queuosine metabolic process
SaSA33_RS09285	COG1328	CTP reductase activity
SaSA33_RS09305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA33_RS09315	COG1393	Belongs to the ArsC family
SaSA33_RS09320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA33_RS09325	COG1058	Belongs to the CinA family
SaSA33_RS09325	COG1546	Belongs to the CinA family
SaSA33_RS09330	COG2818	Glycosylase
SaSA33_RS09370	COG0018	arginyl-trna synthetase
SaSA33_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA33_RS09385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA33_RS09395	COG0124	histidyl-tRNA synthetase
SaSA33_RS09405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA33_RS09420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA33_RS09430	COG0784	Response regulator, receiver
SaSA33_RS09435	COG1125	glycine betaine transport
SaSA33_RS09435	COG0517	IMP dehydrogenase activity
SaSA33_RS09440	COG1174	glycine betaine transport
SaSA33_RS09445	COG0392	lysyltransferase activity
SaSA33_RS09445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA33_RS09455	COG3759	membrane
SaSA33_RS09485	COG0305	Participates in initiation and elongation during chromosome replication
SaSA33_RS09510	COG0482	sulfurtransferase activity
SaSA33_RS09515	COG1760	l-serine dehydratase
SaSA33_RS09520	COG1760	l-serine dehydratase
SaSA33_RS09525	COG0741	lytic transglycosylase activity
SaSA33_RS09550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA33_RS09555	COG0612	Peptidase, M16
SaSA33_RS09560	COG0612	Peptidase, M16
SaSA33_RS09565	COG2501	S4 domain
SaSA33_RS09585	COG0517	IMP dehydrogenase activity
SaSA33_RS09585	COG0516	GMP reductase activity
SaSA33_RS09610	COG0454	-acetyltransferase
SaSA33_RS09615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA33_RS09625	COG0549	Belongs to the carbamate kinase family
SaSA33_RS09640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA33_RS09645	COG0488	(ABC) transporter
SaSA33_RS09650	COG4485	Bacterial membrane protein, YfhO
SaSA33_RS09670	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA33_RS09675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA33_RS09680	COG1475	DNA binding