locus-tag	class	description
OFY20_RS00010	COG0592	DNA-directed DNA polymerase activity
OFY20_RS00015	COG1597	lipid kinase activity
OFY20_RS00030	COG0012	GTP binding
OFY20_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OFY20_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OFY20_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OFY20_RS00260	COG0436	Aminotransferase
OFY20_RS00275	COG0416	fatty acid biosynthetic process
OFY20_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFY20_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFY20_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OFY20_RS00315	COG0138	bifunctional purine biosynthesis protein purh
OFY20_RS00330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OFY20_RS00340	COG1175	transmembrane transport
OFY20_RS00345	COG0395	ABC-type sugar transport system, permease component
OFY20_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OFY20_RS00370	COG3458	cephalosporin-C deacetylase activity
OFY20_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OFY20_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OFY20_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFY20_RS00425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OFY20_RS00425	COG2755	lipolytic protein G-D-S-L family
OFY20_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
OFY20_RS00430	COG1454	alcohol dehydrogenase
OFY20_RS00435	COG1064	alcohol dehydrogenase
OFY20_RS00445	COG0534	Mate efflux family protein
OFY20_RS00555	COG0201	protein transport
OFY20_RS00560	COG0563	adenylate kinase activity
OFY20_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OFY20_RS00585	COG0202	RNA polymerase activity
OFY20_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
OFY20_RS00745	COG0443	Heat shock 70 kDa protein
OFY20_RS00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OFY20_RS00765	COG0351	phosphomethylpyrimidine kinase
OFY20_RS00770	COG4720	Psort location CytoplasmicMembrane, score
OFY20_RS00780	COG0668	transmembrane transport
OFY20_RS00810	COG0756	dUTP diphosphatase activity
OFY20_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OFY20_RS00835	COG1879	ABC-type sugar transport system periplasmic component
OFY20_RS00840	COG1172	Belongs to the binding-protein-dependent transport system permease family
OFY20_RS00855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OFY20_RS00860	COG1609	Transcriptional regulator
OFY20_RS00865	COG0577	efflux transmembrane transporter activity
OFY20_RS00870	COG1136	(ABC) transporter
OFY20_RS00875	COG0745	RESPONSE REGULATOR receiver
OFY20_RS00880	COG5002	protein histidine kinase activity
OFY20_RS00895	COG0191	fructose-bisphosphate aldolase activity
OFY20_RS00915	COG1461	Dihydroxyacetone kinase
OFY20_RS00935	COG1126	abc transporter atp-binding protein
OFY20_RS00940	COG0765	amino acid transport
OFY20_RS00960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OFY20_RS00970	COG0719	Fe-S assembly protein
OFY20_RS00975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OFY20_RS00985	COG0719	Fe-S assembly protein
OFY20_RS00990	COG1686	Belongs to the peptidase S11 family
OFY20_RS00995	COG1686	Belongs to the peptidase S11 family
OFY20_RS01000	COG4166	transmembrane transport
OFY20_RS01005	COG0601	transmembrane transport
OFY20_RS01010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFY20_RS01015	COG0444	Belongs to the ABC transporter superfamily
OFY20_RS01020	COG4608	Belongs to the ABC transporter superfamily
OFY20_RS01060	COG1121	(ABC) transporter
OFY20_RS01065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OFY20_RS01080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OFY20_RS01080	COG4499	WXG100 protein secretion system (Wss), protein YukC
OFY20_RS01100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OFY20_RS01105	COG1459	type II secretion system
OFY20_RS01150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFY20_RS01155	COG1363	Peptidase, m42
OFY20_RS01170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OFY20_RS01175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFY20_RS01190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OFY20_RS01210	COG1346	cytolysis
OFY20_RS01220	COG0601	transmembrane transport
OFY20_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFY20_RS01230	COG1122	ATPase activity
OFY20_RS01240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS01240	COG1263	PTS System
OFY20_RS01245	COG0366	Alpha amylase catalytic
OFY20_RS01250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OFY20_RS01265	COG3959	Transketolase, thiamine diphosphate binding domain
OFY20_RS01270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OFY20_RS01275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OFY20_RS01295	COG1045	serine acetyltransferase
OFY20_RS01310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OFY20_RS01335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OFY20_RS01345	COG4974	Belongs to the 'phage' integrase family
OFY20_RS01445	COG5433	transposase activity
OFY20_RS01455	COG1396	sequence-specific DNA binding
OFY20_RS01460	COG2814	Major facilitator Superfamily
OFY20_RS01470	COG1732	Glycine betaine
OFY20_RS01600	COG0519	Catalyzes the synthesis of GMP from XMP
OFY20_RS01650	COG1695	Transcriptional regulator
OFY20_RS01665	COG1755	Isoprenylcysteine carboxyl methyltransferase
OFY20_RS01705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OFY20_RS01710	COG0446	pyridine nucleotide-disulphide oxidoreductase
OFY20_RS01730	COG1131	(ABC) transporter
OFY20_RS01740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS01740	COG1263	PTS System
OFY20_RS01740	COG2190	(PTS) system
OFY20_RS01745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFY20_RS01765	COG0768	penicillin binding
OFY20_RS01775	COG0513	Belongs to the DEAD box helicase family
OFY20_RS01790	COG1126	abc transporter atp-binding protein
OFY20_RS01800	COG0492	ferredoxin-NADP+ reductase activity
OFY20_RS01805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OFY20_RS01815	COG3579	cysteine-type endopeptidase activity
OFY20_RS01820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OFY20_RS01845	COG0116	Belongs to the methyltransferase superfamily
OFY20_RS01855	COG1854	S-ribosylhomocysteine lyase activity
OFY20_RS01860	COG1418	mRNA catabolic process
OFY20_RS01860	COG4372	Transposase
OFY20_RS01865	COG1131	(ABC) transporter
OFY20_RS01875	COG4585	Histidine kinase
OFY20_RS01880	COG2197	response regulator
OFY20_RS01890	COG0194	GDP metabolic process
OFY20_RS01900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFY20_RS01905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OFY20_RS01910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OFY20_RS01910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OFY20_RS01920	COG0515	serine threonine protein kinase
OFY20_RS01920	COG2815	serine threonine protein kinase
OFY20_RS01930	COG4585	Histidine kinase
OFY20_RS01935	COG2197	response regulator
OFY20_RS01945	COG1098	S1 RNA binding domain
OFY20_RS01950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OFY20_RS01955	COG1349	DNA-binding transcription factor activity
OFY20_RS01965	COG1447	Phosphotransferase system cellobiose-specific component IIA
OFY20_RS01975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OFY20_RS01980	COG1882	Formate acetyltransferase
OFY20_RS02000	COG1739	Uncharacterized protein family UPF0029
OFY20_RS02005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OFY20_RS02010	COG1040	competence protein
OFY20_RS02045	COG0527	aspartate kinase activity
OFY20_RS02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OFY20_RS02055	COG1024	Enoyl-CoA hydratase
OFY20_RS02065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFY20_RS02075	COG2070	2-Nitropropane dioxygenase
OFY20_RS02080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OFY20_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
OFY20_RS02090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OFY20_RS02105	COG0439	Biotin carboxylase
OFY20_RS02125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OFY20_RS02140	COG3716	PTS system mannose fructose sorbose family IID component
OFY20_RS02145	COG3715	PTS system
OFY20_RS02155	COG0561	phosphatase activity
OFY20_RS02170	COG2252	PERMEase
OFY20_RS02175	COG0802	atpase or kinase
OFY20_RS02185	COG1316	TRANSCRIPTIONal
OFY20_RS02195	COG0537	adenosine 5'-monophosphoramidase activity
OFY20_RS02210	COG1131	(ABC) transporter
OFY20_RS02215	COG4473	ABC transporter
OFY20_RS02225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OFY20_RS02240	COG0195	Participates in both transcription termination and antitermination
OFY20_RS02245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OFY20_RS02260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OFY20_RS02285	COG2860	membrane
OFY20_RS02295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS02295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS02300	COG1832	CoA-binding protein
OFY20_RS02320	COG5002	protein histidine kinase activity
OFY20_RS02340	COG1268	BioY protein
OFY20_RS02345	COG1234	tRNA 3'-trailer cleavage
OFY20_RS02360	COG0166	Belongs to the GPI family
OFY20_RS02365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OFY20_RS02370	COG0457	Tetratricopeptide repeat
OFY20_RS02370	COG0705	Rhomboid family
OFY20_RS02375	COG1744	ABC transporter substrate-binding protein PnrA-like
OFY20_RS02380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OFY20_RS02395	COG0706	membrane insertase activity
OFY20_RS02455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFY20_RS02465	COG2153	protein acetylation
OFY20_RS02475	COG1216	Glycosyl transferase, family 2
OFY20_RS02475	COG1442	glycosyl transferase family 8
OFY20_RS02520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OFY20_RS02530	COG0789	Transcriptional regulator
OFY20_RS02600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OFY20_RS02610	COG0525	valine-tRNA ligase activity
OFY20_RS02620	COG0673	inositol 2-dehydrogenase activity
OFY20_RS02630	COG2315	Protein conserved in bacteria
OFY20_RS02645	COG0742	ribosomal rna small subunit methyltransferase
OFY20_RS02660	COG3480	Lon protease (S16) C-terminal proteolytic domain
OFY20_RS02670	COG4470	Protein conserved in bacteria
OFY20_RS02685	COG1132	(ABC) transporter
OFY20_RS02690	COG1132	(ABC) transporter
OFY20_RS02695	COG0512	Glutamine amidotransferase of anthranilate synthase
OFY20_RS02700	COG1268	BioY protein
OFY20_RS02715	COG0183	Belongs to the thiolase family
OFY20_RS02725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OFY20_RS02740	COG1940	carbohydrate kinase activity
OFY20_RS02745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OFY20_RS02750	COG1217	gtp-binding protein TYPA
OFY20_RS02785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OFY20_RS02795	COG0762	integral membrane protein
OFY20_RS02800	COG2302	S4 RNA-binding domain
OFY20_RS02805	COG3599	regulation of cell shape
OFY20_RS02820	COG0494	nUDIX hydrolase
OFY20_RS02825	COG0542	response to heat
OFY20_RS02830	COG4703	Protein of unknown function (DUF1797)
OFY20_RS02835	COG0765	amino acid transport
OFY20_RS02840	COG1126	abc transporter atp-binding protein
OFY20_RS02845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OFY20_RS02855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OFY20_RS02865	COG1722	exodeoxyribonuclease VII activity
OFY20_RS02875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OFY20_RS02880	COG1438	arginine binding
OFY20_RS02885	COG0497	DNA recombination
OFY20_RS02890	COG1307	EDD domain protein, DegV family
OFY20_RS02895	COG2755	lipolytic protein G-D-S-L family
OFY20_RS02940	COG1078	dGTPase activity
OFY20_RS02965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OFY20_RS02975	COG2884	Cell division ATP-binding protein ftsE
OFY20_RS02980	COG2177	Part of the ABC transporter FtsEX involved in
OFY20_RS03000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OFY20_RS03000	COG1199	ATP-dependent helicase activity
OFY20_RS03005	COG0436	Aminotransferase
OFY20_RS03010	COG0017	Asparaginyl-tRNA synthetase
OFY20_RS03030	COG1660	Displays ATPase and GTPase activities
OFY20_RS03055	COG0254	rRNA binding
OFY20_RS03060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OFY20_RS03065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OFY20_RS03070	COG0716	FMN binding
OFY20_RS03075	COG1605	Chorismate mutase
OFY20_RS03075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OFY20_RS03080	COG0038	chloride channel
OFY20_RS03090	COG0335	large ribosomal subunit rRNA binding
OFY20_RS03100	COG0582	viral genome integration into host DNA
OFY20_RS03275	COG1598	PFAM Uncharacterised protein family UPF0150
OFY20_RS03455	COG1136	(ABC) transporter
OFY20_RS03470	COG5002	protein histidine kinase activity
OFY20_RS03490	COG0772	Belongs to the SEDS family
OFY20_RS03510	COG0560	Phosphoserine phosphatase
OFY20_RS03530	COG5433	transposase activity
OFY20_RS03535	COG0148	phosphopyruvate hydratase activity
OFY20_RS03555	COG1316	TRANSCRIPTIONal
OFY20_RS03595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS03595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS03650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFY20_RS03710	COG4695	Portal protein
OFY20_RS03715	COG0740	serine-type endopeptidase activity
OFY20_RS03780	COG1705	Flagellar rod assembly protein muramidase FlgJ
OFY20_RS03795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OFY20_RS03820	COG3700	Belongs to the class B bacterial acid phosphatase family
OFY20_RS03930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OFY20_RS03935	COG4555	ABC transporter
OFY20_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
OFY20_RS03965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFY20_RS03970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OFY20_RS03990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OFY20_RS03995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OFY20_RS04015	COG3064	Membrane
OFY20_RS04015	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OFY20_RS04030	COG3590	peptidase
OFY20_RS04035	COG3590	peptidase
OFY20_RS04085	COG1136	(ABC) transporter
OFY20_RS04100	COG0586	Pfam SNARE associated Golgi protein
OFY20_RS04105	COG4619	ABC transporter
OFY20_RS04110	COG0390	transport system, permease component
OFY20_RS04120	COG0583	DNA-binding transcription factor activity
OFY20_RS04135	COG5433	transposase activity
OFY20_RS04150	COG2211	Major facilitator Superfamily
OFY20_RS04160	COG3250	beta-galactosidase activity
OFY20_RS04165	COG2186	Transcriptional regulator
OFY20_RS04170	COG0800	Aldolase
OFY20_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
OFY20_RS04205	COG1609	Transcriptional regulator
OFY20_RS04220	COG0438	transferase activity, transferring glycosyl groups
OFY20_RS04245	COG0765	amino acid transport
OFY20_RS04250	COG0765	amino acid transport
OFY20_RS04255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OFY20_RS04260	COG1126	abc transporter atp-binding protein
OFY20_RS04265	COG0745	RESPONSE REGULATOR receiver
OFY20_RS04270	COG5002	protein histidine kinase activity
OFY20_RS04275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OFY20_RS04280	COG2832	Protein of unknown function (DUF454)
OFY20_RS04290	COG1196	nuclear chromosome segregation
OFY20_RS04295	COG0561	phosphatase activity
OFY20_RS04300	COG0561	phosphatase activity
OFY20_RS04305	COG0552	protein localization to endoplasmic reticulum
OFY20_RS04310	COG3689	TIGRFAM TIGR03943 family protein
OFY20_RS04315	COG0701	Predicted permease
OFY20_RS04330	COG2183	response to ionizing radiation
OFY20_RS04335	COG3091	SprT-like family
OFY20_RS04340	COG1983	PspC domain protein
OFY20_RS04375	COG0826	peptidase U32
OFY20_RS04380	COG4443	Transcriptional Coactivator p15 (PC4)
OFY20_RS04390	COG1914	H( )-stimulated, divalent metal cation uptake system
OFY20_RS04405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OFY20_RS04405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OFY20_RS04430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OFY20_RS04455	COG1164	Oligoendopeptidase f
OFY20_RS04465	COG0772	Belongs to the SEDS family
OFY20_RS04485	COG0768	penicillin binding
OFY20_RS04500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OFY20_RS04505	COG2223	nitrite transmembrane transporter activity
OFY20_RS04530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OFY20_RS04535	COG2011	ABC-type metal ion transport system permease component
OFY20_RS04540	COG1464	Belongs to the NlpA lipoprotein family
OFY20_RS04545	COG0513	Belongs to the DEAD box helicase family
OFY20_RS04555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OFY20_RS04560	COG0204	Acyl-transferase
OFY20_RS04565	COG1596	polysaccharide export
OFY20_RS04565	COG1555	photosystem II stabilization
OFY20_RS04570	COG2333	competence protein COMEC
OFY20_RS04570	COG0658	competence protein
OFY20_RS04575	COG0561	phosphatase activity
OFY20_RS04580	COG1609	Transcriptional regulator
OFY20_RS04585	COG0657	acetylesterase activity
OFY20_RS04590	COG2226	methyltransferase
OFY20_RS04600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OFY20_RS04605	COG3711	transcriptional antiterminator
OFY20_RS04610	COG2190	(PTS) system
OFY20_RS04610	COG1263	PTS System
OFY20_RS04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS04620	COG3835	regulator
OFY20_RS04625	COG1929	Belongs to the glycerate kinase type-1 family
OFY20_RS04630	COG2610	gluconate transmembrane transporter activity
OFY20_RS04640	COG1846	Transcriptional regulator
OFY20_RS04655	COG0363	glucosamine-6-phosphate deaminase activity
OFY20_RS04660	COG0435	Glutathione S-transferase
OFY20_RS04665	COG1187	pseudouridine synthase activity
OFY20_RS04685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OFY20_RS04690	COG4122	O-methyltransferase activity
OFY20_RS04700	COG4894	glucomannan catabolic process
OFY20_RS04710	COG1811	Na channel or pump
OFY20_RS04715	COG1442	glycosyl transferase family 8
OFY20_RS04730	COG1476	TRANSCRIPTIONal
OFY20_RS04745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFY20_RS04750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFY20_RS04755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OFY20_RS04770	COG1012	belongs to the aldehyde dehydrogenase family
OFY20_RS04775	COG0726	polysaccharide deacetylase
OFY20_RS04790	COG1956	GAF domain-containing protein
OFY20_RS04795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFY20_RS04805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OFY20_RS04805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OFY20_RS04835	COG4721	ABC-type cobalt transport system, permease component
OFY20_RS04840	COG1122	ATPase activity
OFY20_RS04850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OFY20_RS04880	COG4109	DRTGG domain
OFY20_RS04885	COG0024	Methionine aminopeptidase
OFY20_RS04895	COG2246	polysaccharide biosynthetic process
OFY20_RS04900	COG4708	membrane
OFY20_RS04910	COG1597	lipid kinase activity
OFY20_RS04915	COG1523	belongs to the glycosyl hydrolase 13 family
OFY20_RS04930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OFY20_RS05015	COG2321	neutral zinc metallopeptidase
OFY20_RS05040	COG0488	(ABC) transporter
OFY20_RS05045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OFY20_RS05050	COG0022	dehydrogenase e1 component
OFY20_RS05050	COG0508	dehydrogenase complex catalyzes the overall conversion of
OFY20_RS05055	COG0508	dehydrogenase complex catalyzes the overall conversion of
OFY20_RS05065	COG0095	Lipoate-protein ligase
OFY20_RS05070	COG3442	glutamine amidotransferase
OFY20_RS05075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OFY20_RS05080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFY20_RS05105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OFY20_RS05115	COG0647	UMP catabolic process
OFY20_RS05125	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
OFY20_RS05130	COG1518	maintenance of DNA repeat elements
OFY20_RS05135	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFY20_RS05150	COG0481	GTPase activity
OFY20_RS05160	COG1418	mRNA catabolic process
OFY20_RS05165	COG0456	acetyltransferase
OFY20_RS05175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OFY20_RS05250	COG0741	lytic transglycosylase activity
OFY20_RS05250	COG0791	NLP P60 protein
OFY20_RS05280	COG2946	Replication initiation factor
OFY20_RS05290	COG1674	ftsk spoiiie
OFY20_RS05310	COG1131	(ABC) transporter
OFY20_RS05315	COG1725	Transcriptional regulator
OFY20_RS05325	COG0205	6-phosphofructokinase activity
OFY20_RS05330	COG0469	pyruvate kinase activity
OFY20_RS05345	COG5433	transposase activity
OFY20_RS05350	COG2824	Alkylphosphonate utilization operon protein PhnA
OFY20_RS05355	COG0765	amino acid transport
OFY20_RS05360	COG1126	abc transporter atp-binding protein
OFY20_RS05375	COG1072	(Pantothenic acid kinase))
OFY20_RS05380	COG2813	Specifically methylates the guanine in position
OFY20_RS05390	COG1744	ABC transporter substrate-binding protein PnrA-like
OFY20_RS05395	COG3845	ABC transporter
OFY20_RS05400	COG4603	Belongs to the binding-protein-dependent transport system permease family
OFY20_RS05405	COG1079	Belongs to the binding-protein-dependent transport system permease family
OFY20_RS05425	COG3764	Sortase (surface protein transpeptidase)
OFY20_RS05430	COG0346	lactoylglutathione lyase activity
OFY20_RS05455	COG2188	Transcriptional regulator
OFY20_RS05470	COG1464	Belongs to the NlpA lipoprotein family
OFY20_RS05485	COG1136	(ABC) transporter
OFY20_RS05495	COG0745	RESPONSE REGULATOR receiver
OFY20_RS05500	COG5002	protein histidine kinase activity
OFY20_RS05505	COG4974	Belongs to the 'phage' integrase family
OFY20_RS05510	COG4166	transmembrane transport
OFY20_RS05525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OFY20_RS05530	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OFY20_RS05535	COG5002	protein histidine kinase activity
OFY20_RS05540	COG0745	RESPONSE REGULATOR receiver
OFY20_RS05550	COG0704	Plays a role in the regulation of phosphate uptake
OFY20_RS05555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OFY20_RS05560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OFY20_RS05565	COG0581	inorganic phosphate transmembrane transporter activity
OFY20_RS05570	COG0573	inorganic phosphate transmembrane transporter activity
OFY20_RS05580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OFY20_RS05580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OFY20_RS05585	COG0483	inositol monophosphate 1-phosphatase activity
OFY20_RS05600	COG0196	riboflavin kinase activity
OFY20_RS05605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OFY20_RS05635	COG1136	(ABC) transporter
OFY20_RS05640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFY20_RS05645	COG0758	DNA mediated transformation
OFY20_RS05650	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OFY20_RS05655	COG4604	ABC transporter, ATP-binding protein
OFY20_RS05660	COG4605	iron ion homeostasis
OFY20_RS05665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFY20_RS05670	COG0110	maltose O-acetyltransferase activity
OFY20_RS05680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFY20_RS05685	COG1376	ErfK ybiS ycfS ynhG family protein
OFY20_RS05690	COG1966	Carbon starvation protein
OFY20_RS05695	COG3279	Response regulator of the LytR AlgR family
OFY20_RS05700	COG3275	phosphorelay sensor kinase activity
OFY20_RS05745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OFY20_RS05750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OFY20_RS05765	COG0488	(ABC) transporter
OFY20_RS05775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OFY20_RS05785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFY20_RS05825	COG0095	Lipoate-protein ligase
OFY20_RS05835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OFY20_RS05840	COG4684	Psort location CytoplasmicMembrane, score
OFY20_RS05845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OFY20_RS05860	COG1132	(ABC) transporter
OFY20_RS05890	COG2890	protein-(glutamine-N5) methyltransferase activity
OFY20_RS05905	COG1942	4-Oxalocrotonate Tautomerase
OFY20_RS05920	COG0431	NADPH-dependent FMN reductase
OFY20_RS05920	COG1053	succinate dehydrogenase
OFY20_RS05920	COG3976	FMN-binding domain protein
OFY20_RS05930	COG2233	PERMEase
OFY20_RS05945	COG0477	Major facilitator Superfamily
OFY20_RS05960	COG4221	oxidoreductase activity
OFY20_RS05965	COG0280	phosphate acetyltransferase
OFY20_RS05970	COG0564	pseudouridine synthase activity
OFY20_RS05980	COG2357	RelA SpoT domain protein
OFY20_RS05995	COG1104	cysteine desulfurase activity
OFY20_RS06015	COG0628	permease
OFY20_RS06030	COG0561	phosphatase activity
OFY20_RS06055	COG1388	LysM domain
OFY20_RS06055	COG0860	N-Acetylmuramoyl-L-alanine amidase
OFY20_RS06120	COG0740	serine-type endopeptidase activity
OFY20_RS06125	COG4695	Portal protein
OFY20_RS06165	COG0270	DNA (cytosine-5-)-methyltransferase activity
OFY20_RS06190	COG3041	Addiction module toxin RelE StbE family
OFY20_RS06200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFY20_RS06240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS06240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFY20_RS06285	COG4372	Transposase
OFY20_RS06320	COG0038	chloride channel
OFY20_RS06330	COG1177	transmembrane transport
OFY20_RS06335	COG1176	ABC-type spermidine putrescine transport system, permease component I
OFY20_RS06345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OFY20_RS06350	COG5433	transposase activity
OFY20_RS06355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OFY20_RS06375	COG0285	dihydrofolate synthase activity
OFY20_RS06380	COG2962	Rard protein
OFY20_RS06395	COG5433	transposase activity
OFY20_RS06400	COG0726	polysaccharide deacetylase
OFY20_RS06405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OFY20_RS06410	COG1012	belongs to the aldehyde dehydrogenase family
OFY20_RS06485	COG2261	transglycosylase associated protein
OFY20_RS06510	COG1115	amino acid carrier protein
OFY20_RS06515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFY20_RS06525	COG1346	cytolysis
OFY20_RS06540	COG0539	negative regulation of cytoplasmic translation
OFY20_RS06560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OFY20_RS06570	COG0187	DNA topoisomerase II activity
OFY20_RS06575	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OFY20_RS06580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OFY20_RS06605	COG2089	acid synthase
OFY20_RS06620	COG1442	glycosyl transferase family 8
OFY20_RS06620	COG1216	Glycosyl transferase, family 2
OFY20_RS06625	COG1215	transferase activity, transferring glycosyl groups
OFY20_RS06630	COG0463	Glycosyl transferase, family 2
OFY20_RS06650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OFY20_RS06685	COG5433	transposase activity
OFY20_RS06715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OFY20_RS06750	COG3842	ATPase activity
OFY20_RS06765	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OFY20_RS06770	COG3527	Alpha-acetolactate decarboxylase
OFY20_RS06775	COG0028	Belongs to the TPP enzyme family
OFY20_RS06780	COG0457	Tetratricopeptide repeat
OFY20_RS06785	COG0628	permease
OFY20_RS06795	COG1051	belongs to the nudix hydrolase family
OFY20_RS06800	COG5492	domain, Protein
OFY20_RS06805	COG1088	dTDP-glucose 4,6-dehydratase activity
OFY20_RS06815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OFY20_RS06820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OFY20_RS06830	COG2384	SAM-dependent methyltransferase
OFY20_RS06850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OFY20_RS06850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OFY20_RS06855	COG0300	oxidoreductase activity
OFY20_RS06870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OFY20_RS06900	COG1573	uracil-dna glycosylase
OFY20_RS06905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OFY20_RS06930	COG0534	Mate efflux family protein
OFY20_RS06970	COG0803	Belongs to the bacterial solute-binding protein 9 family
OFY20_RS06980	COG5433	transposase activity
OFY20_RS07000	COG2176	DNA-directed DNA polymerase activity
OFY20_RS07010	COG4974	Belongs to the 'phage' integrase family
OFY20_RS07020	COG1396	sequence-specific DNA binding
OFY20_RS07025	COG3843	relaxase mobilization nuclease domain protein
OFY20_RS07040	COG0613	PHP domain protein
OFY20_RS07045	COG0542	response to heat
OFY20_RS07050	COG1396	sequence-specific DNA binding
OFY20_RS07105	COG1136	(ABC) transporter
OFY20_RS07125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OFY20_RS07125	COG0456	acetyltransferase
OFY20_RS07140	COG0488	(ABC) transporter
OFY20_RS07150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OFY20_RS07170	COG1388	LysM domain
OFY20_RS07170	COG0791	NLP P60 protein
OFY20_RS07255	COG0270	DNA (cytosine-5-)-methyltransferase activity
OFY20_RS07280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFY20_RS07280	COG0551	DNA topoisomerase type I activity
OFY20_RS07340	COG4804	nuclease activity
OFY20_RS07385	COG0534	Mate efflux family protein
OFY20_RS07425	COG0640	Transcriptional regulator
OFY20_RS07435	COG2217	Heavy metal translocating P-type atpase
OFY20_RS07470	COG0582	viral genome integration into host DNA
OFY20_RS07530	COG1129	ABC transporter
OFY20_RS07535	COG1132	(ABC) transporter
OFY20_RS07540	COG1132	(ABC) transporter
OFY20_RS07550	COG1309	transcriptional regulator
OFY20_RS07670	COG0270	DNA (cytosine-5-)-methyltransferase activity
OFY20_RS07700	COG2040	homocysteine
OFY20_RS07735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OFY20_RS07745	COG3425	synthase
OFY20_RS07760	COG1272	protein, Hemolysin III
OFY20_RS07805	COG5433	transposase activity
OFY20_RS07815	COG0745	RESPONSE REGULATOR receiver
OFY20_RS07820	COG2357	RelA SpoT domain protein
OFY20_RS07825	COG1132	(ABC) transporter
OFY20_RS07840	COG0737	Belongs to the 5'-nucleotidase family
OFY20_RS07845	COG0242	peptide deformylase activity
OFY20_RS07850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OFY20_RS07860	COG1132	(ABC) transporter
OFY20_RS07875	COG0488	(ABC) transporter
OFY20_RS07905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OFY20_RS07905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OFY20_RS07905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OFY20_RS07910	COG1105	Belongs to the carbohydrate kinase PfkB family
OFY20_RS07915	COG1349	DNA-binding transcription factor activity
OFY20_RS07920	COG1705	Flagellar rod assembly protein muramidase FlgJ
OFY20_RS07920	COG1388	LysM domain
OFY20_RS07970	COG1837	Belongs to the UPF0109 family
OFY20_RS07975	COG0228	four-way junction DNA binding
OFY20_RS07980	COG0577	efflux transmembrane transporter activity
OFY20_RS07985	COG1136	(ABC) transporter
OFY20_RS07990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OFY20_RS08000	COG0505	Belongs to the CarA family
OFY20_RS08010	COG0564	pseudouridine synthase activity
OFY20_RS08020	COG0583	DNA-binding transcription factor activity
OFY20_RS08025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OFY20_RS08050	COG1104	cysteine desulfurase activity
OFY20_RS08060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OFY20_RS08085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OFY20_RS08090	COG1368	sulfuric ester hydrolase activity
OFY20_RS08095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OFY20_RS08105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OFY20_RS08135	COG2244	polysaccharide biosynthetic process
OFY20_RS08145	COG1120	ATPase activity
OFY20_RS08150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OFY20_RS08155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFY20_RS08160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFY20_RS08175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OFY20_RS08180	COG1253	flavin adenine dinucleotide binding
OFY20_RS08185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OFY20_RS08190	COG1242	4 iron, 4 sulfur cluster binding
OFY20_RS08195	COG0671	phosphoesterase, PA-phosphatase related
OFY20_RS08200	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OFY20_RS08240	COG0297	glycogen (starch) synthase activity
OFY20_RS08280	COG3475	LICD family
OFY20_RS08295	COG0463	Glycosyl transferase, family 2
OFY20_RS08300	COG1215	transferase activity, transferring glycosyl groups
OFY20_RS08310	COG1091	dTDP-4-dehydrorhamnose reductase activity
OFY20_RS08315	COG2151	metal-sulfur cluster biosynthetic enzyme
OFY20_RS08320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFY20_RS08325	COG0358	DNA primase activity
OFY20_RS08330	COG1970	mechanosensitive ion channel activity
OFY20_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OFY20_RS08350	COG0004	ammonium transporteR
OFY20_RS08360	COG1054	Belongs to the UPF0176 family
OFY20_RS08370	COG2271	Major facilitator Superfamily
OFY20_RS08375	COG0058	SHG alpha-glucan phosphorylase activity
OFY20_RS08380	COG1640	4-alpha-glucanotransferase
OFY20_RS08385	COG1609	Transcriptional regulator
OFY20_RS08395	COG1175	transmembrane transport
OFY20_RS08400	COG3833	ABC-type maltose transport systems, permease component
OFY20_RS08405	COG3104	oligopeptide transport
OFY20_RS08425	COG0438	transferase activity, transferring glycosyl groups
OFY20_RS08450	COG0201	protein transport
OFY20_RS08495	COG0765	amino acid transport
OFY20_RS08500	COG1126	abc transporter atp-binding protein
OFY20_RS08525	COG2309	aminopeptidase activity
OFY20_RS08535	COG0154	amidase activity
OFY20_RS08540	COG1187	pseudouridine synthase activity
OFY20_RS08545	COG0656	L-ascorbic acid biosynthetic process
OFY20_RS08550	COG0778	Nitroreductase
OFY20_RS08555	COG0346	lactoylglutathione lyase activity
OFY20_RS08560	COG0463	Glycosyl transferase, family 2
OFY20_RS08565	COG1113	amino acid transport
OFY20_RS08570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OFY20_RS08575	COG0557	exoribonuclease II activity
OFY20_RS08590	COG2814	Major facilitator Superfamily
OFY20_RS08600	COG1131	(ABC) transporter
OFY20_RS08610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OFY20_RS08615	COG1396	sequence-specific DNA binding
OFY20_RS08665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OFY20_RS08670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OFY20_RS08690	COG1702	phosphate starvation-inducible protein PhoH
OFY20_RS08715	COG0233	cytoplasmic translational termination
OFY20_RS08730	COG0444	Belongs to the ABC transporter superfamily
OFY20_RS08735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFY20_RS08740	COG0601	transmembrane transport
OFY20_RS08745	COG0747	negative chemotaxis
OFY20_RS08750	COG0081	regulation of translation
OFY20_RS08770	COG1473	amidohydrolase
OFY20_RS08775	COG0583	DNA-binding transcription factor activity
OFY20_RS08790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFY20_RS08800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OFY20_RS08825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OFY20_RS08855	COG0673	inositol 2-dehydrogenase activity
OFY20_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
OFY20_RS08925	COG1114	Component of the transport system for branched-chain amino acids
OFY20_RS08930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFY20_RS08930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFY20_RS08945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OFY20_RS08955	COG0708	Exodeoxyribonuclease III
OFY20_RS08960	COG1393	Belongs to the ArsC family
OFY20_RS08965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OFY20_RS08970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFY20_RS09000	COG0470	DNA polymerase III
OFY20_RS09015	COG0517	IMP dehydrogenase activity
OFY20_RS09035	COG0559	Belongs to the binding-protein-dependent transport system permease family
OFY20_RS09055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OFY20_RS09060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OFY20_RS09070	COG0531	amino acid
OFY20_RS09075	COG0569	domain protein
OFY20_RS09080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OFY20_RS09090	COG1187	pseudouridine synthase activity
OFY20_RS09140	COG1827	regulation of RNA biosynthetic process
OFY20_RS09155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFY20_RS09160	COG1254	Belongs to the acylphosphatase family
OFY20_RS09170	COG0765	amino acid transport
OFY20_RS09175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OFY20_RS09190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFY20_RS09220	COG1484	DNA-dependent DNA replication
OFY20_RS09235	COG5002	protein histidine kinase activity
OFY20_RS09240	COG0745	RESPONSE REGULATOR receiver
OFY20_RS09255	COG1704	LemA family
OFY20_RS09265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OFY20_RS09270	COG0569	domain protein
OFY20_RS09295	COG1114	Component of the transport system for branched-chain amino acids
OFY20_RS09300	COG1063	alcohol dehydrogenase
OFY20_RS09325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OFY20_RS09330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OFY20_RS09335	COG0217	transcriptional regulatory protein
OFY20_RS09340	COG2376	Dihydroxyacetone kinase
OFY20_RS09345	COG1309	transcriptional regulator
OFY20_RS09350	COG2376	Dihydroxyacetone kinase
OFY20_RS09355	COG1461	Dihydroxyacetone kinase
OFY20_RS09360	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OFY20_RS09365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OFY20_RS09375	COG0789	Transcriptional regulator
OFY20_RS09390	COG2226	methyltransferase
OFY20_RS09395	COG0799	negative regulation of ribosome biogenesis
OFY20_RS09405	COG1713	HD superfamily hydrolase involved in NAD metabolism
OFY20_RS09410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OFY20_RS09415	COG1534	Rna-binding protein
OFY20_RS09420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFY20_RS09425	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OFY20_RS09450	COG0574	Belongs to the PEP-utilizing enzyme family
OFY20_RS09450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OFY20_RS09460	COG0517	IMP dehydrogenase activity
OFY20_RS09470	COG1335	isochorismatase
OFY20_RS09475	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OFY20_RS09480	COG0436	Aminotransferase
OFY20_RS09485	COG0589	response to stress
OFY20_RS09490	COG0561	phosphatase activity
OFY20_RS09495	COG0252	asparaginase activity
OFY20_RS09505	COG4989	oxidoreductase activity
OFY20_RS09510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OFY20_RS09515	COG3942	CHAP domain
OFY20_RS09515	COG1705	Flagellar rod assembly protein muramidase FlgJ
OFY20_RS09525	COG0736	holo-[acyl-carrier-protein] synthase activity
OFY20_RS09530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OFY20_RS09540	COG1482	cell wall glycoprotein biosynthetic process
OFY20_RS09545	COG1940	carbohydrate kinase activity
OFY20_RS09550	COG1263	PTS System
OFY20_RS09550	COG2190	(PTS) system
OFY20_RS09550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS09555	COG1621	beta-fructofuranosidase activity
OFY20_RS09560	COG1609	Transcriptional regulator
OFY20_RS09565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OFY20_RS09575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OFY20_RS09605	COG2131	deaminase
OFY20_RS09620	COG2814	Major facilitator Superfamily
OFY20_RS09645	COG0629	single-stranded DNA binding
OFY20_RS09650	COG0360	Binds together with S18 to 16S ribosomal RNA
OFY20_RS09660	COG1194	a g-specific adenine glycosylase
OFY20_RS09670	COG3118	belongs to the thioredoxin family
OFY20_RS09700	COG0681	Belongs to the peptidase S26 family
OFY20_RS09705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OFY20_RS09720	COG1882	Formate acetyltransferase
OFY20_RS09725	COG3576	pyridoxamine 5-phosphate
OFY20_RS09730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OFY20_RS09745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OFY20_RS09755	COG2814	Major facilitator Superfamily
OFY20_RS09760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OFY20_RS09775	COG0142	geranyltranstransferase activity
OFY20_RS09780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OFY20_RS09785	COG4988	ABC transporter
OFY20_RS09790	COG1294	oxidase, subunit
OFY20_RS09795	COG1271	oxidase subunit
OFY20_RS09800	COG1252	NADH dehydrogenase
OFY20_RS09815	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OFY20_RS09820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OFY20_RS09825	COG0789	Transcriptional regulator
OFY20_RS09840	COG2081	HI0933 family
OFY20_RS09865	COG0456	acetyltransferase
OFY20_RS09870	COG1214	PFAM Peptidase M22, glycoprotease
OFY20_RS09885	COG3942	CHAP domain
OFY20_RS09890	COG0174	glutamine synthetase
OFY20_RS09895	COG0789	Transcriptional regulator
OFY20_RS09910	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OFY20_RS09935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OFY20_RS09985	COG0084	hydrolase, TatD family'
OFY20_RS10010	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OFY20_RS10015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFY20_RS10020	COG1696	Membrane protein involved in D-alanine export
OFY20_RS10040	COG0745	RESPONSE REGULATOR receiver
OFY20_RS10050	COG3314	Sporulation integral membrane protein YlbJ
OFY20_RS10065	COG3448	diguanylate cyclase activity
OFY20_RS10065	COG4175	Glycine betaine
OFY20_RS10070	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OFY20_RS10090	COG1070	Carbohydrate kinase
OFY20_RS10100	COG3775	system Galactitol-specific IIC component
OFY20_RS10105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFY20_RS10115	COG1609	Transcriptional regulator
OFY20_RS10165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OFY20_RS10195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OFY20_RS10200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFY20_RS10205	COG1428	Deoxynucleoside kinase
OFY20_RS10215	COG0542	response to heat
OFY20_RS10220	COG4463	regulation of RNA biosynthetic process
OFY20_RS10230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OFY20_RS10240	COG0450	alkyl hydroperoxide reductase
OFY20_RS10255	COG0025	NhaP-type Na H and K H
OFY20_RS10265	COG1619	proteins homologs of microcin C7 resistance protein MccF
OFY20_RS10270	COG3590	peptidase
OFY20_RS10295	COG1609	Transcriptional regulator
OFY20_RS10305	COG3716	PTS system mannose fructose sorbose family IID component
OFY20_RS10310	COG3715	PTS system
OFY20_RS10315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS10320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OFY20_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
OFY20_RS10365	COG2176	DNA-directed DNA polymerase activity
OFY20_RS10370	COG1388	LysM domain
OFY20_RS10370	COG1705	Flagellar rod assembly protein muramidase FlgJ
OFY20_RS10385	COG4589	Belongs to the CDS family
OFY20_RS10390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OFY20_RS10395	COG1862	Preprotein translocase
OFY20_RS10410	COG3493	citrate carrier protein
OFY20_RS10415	COG3290	protein histidine kinase activity
OFY20_RS10420	COG4565	transcriptional regulatory protein
OFY20_RS10425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OFY20_RS10435	COG3842	ATPase activity
OFY20_RS10505	COG1490	D-aminoacyl-tRNA deacylase activity
OFY20_RS10515	COG0737	Belongs to the 5'-nucleotidase family
OFY20_RS10525	COG1363	Peptidase, m42
OFY20_RS10540	COG4753	response regulator
OFY20_RS10540	COG2207	Transcriptional regulator
OFY20_RS10545	COG2972	Histidine kinase
OFY20_RS10550	COG3716	PTS system mannose fructose sorbose family IID component
OFY20_RS10555	COG3715	PTS system
OFY20_RS10580	COG1131	(ABC) transporter
OFY20_RS10590	COG3279	Response regulator of the LytR AlgR family
OFY20_RS10600	COG1263	PTS System
OFY20_RS10600	COG2190	(PTS) system
OFY20_RS10600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFY20_RS10605	COG5002	protein histidine kinase activity
OFY20_RS10610	COG0745	RESPONSE REGULATOR receiver
OFY20_RS10620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OFY20_RS10625	COG0581	inorganic phosphate transmembrane transporter activity
OFY20_RS10630	COG0573	inorganic phosphate transmembrane transporter activity
OFY20_RS10645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OFY20_RS10660	COG0789	Transcriptional regulator
OFY20_RS10685	COG0456	acetyltransferase
OFY20_RS10690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OFY20_RS10700	COG0582	viral genome integration into host DNA
OFY20_RS10745	COG5433	transposase activity
OFY20_RS10755	COG0433	COG0433 Predicted ATPase
OFY20_RS10775	COG4115	mRNA cleavage
OFY20_RS10820	COG1674	ftsk spoiiie
OFY20_RS10855	COG1914	H( )-stimulated, divalent metal cation uptake system
OFY20_RS10865	COG1131	(ABC) transporter
OFY20_RS10905	COG1131	(ABC) transporter
OFY20_RS10915	COG1396	sequence-specific DNA binding
OFY20_RS10925	COG1694	Mazg nucleotide pyrophosphohydrolase
OFY20_RS10955	COG0371	Dehydrogenase
OFY20_RS10965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OFY20_RS10965	COG0646	methionine synthase
OFY20_RS10970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OFY20_RS10980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OFY20_RS10990	COG0745	RESPONSE REGULATOR receiver
OFY20_RS10995	COG2205	protein histidine kinase activity
OFY20_RS10995	COG2770	Histidine kinase
OFY20_RS11005	COG0495	leucyl-tRNA aminoacylation
OFY20_RS11010	COG5433	transposase activity
OFY20_RS11020	COG2814	Major facilitator Superfamily
OFY20_RS11025	COG4667	esterase of the alpha-beta hydrolase superfamily
OFY20_RS11030	COG1442	glycosyl transferase family 8
OFY20_RS11035	COG1442	glycosyl transferase family 8
OFY20_RS11060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OFY20_RS11065	COG0564	pseudouridine synthase activity
OFY20_RS11085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFY20_RS11090	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
OFY20_RS11110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OFY20_RS11115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OFY20_RS11115	COG1116	anion transmembrane transporter activity
OFY20_RS11120	COG4120	Belongs to the binding-protein-dependent transport system permease family
OFY20_RS11130	COG0561	phosphatase activity
OFY20_RS11135	COG2514	catechol 2,3-dioxygenase activity
OFY20_RS11145	COG0602	queuosine metabolic process
OFY20_RS11165	COG1328	CTP reductase activity
OFY20_RS11185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OFY20_RS11195	COG1393	Belongs to the ArsC family
OFY20_RS11200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OFY20_RS11210	COG2818	Glycosylase
OFY20_RS11225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OFY20_RS11255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFY20_RS11260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFY20_RS11270	COG0124	histidyl-tRNA synthetase
OFY20_RS11280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OFY20_RS11290	COG0745	RESPONSE REGULATOR receiver
OFY20_RS11295	COG5002	protein histidine kinase activity
OFY20_RS11300	COG1288	antiporter activity
OFY20_RS11310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OFY20_RS11315	COG3852	Histidine kinase
OFY20_RS11320	COG0784	Response regulator, receiver
OFY20_RS11325	COG0517	IMP dehydrogenase activity
OFY20_RS11325	COG1125	glycine betaine transport
OFY20_RS11330	COG1174	glycine betaine transport
OFY20_RS11335	COG0392	lysyltransferase activity
OFY20_RS11335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OFY20_RS11345	COG3759	membrane
OFY20_RS11375	COG0305	Participates in initiation and elongation during chromosome replication
OFY20_RS11390	COG0445	tRNA wobble uridine modification
OFY20_RS11395	COG2095	MarC family integral membrane protein
OFY20_RS11400	COG0482	sulfurtransferase activity
OFY20_RS11405	COG1760	l-serine dehydratase
OFY20_RS11410	COG1760	l-serine dehydratase
OFY20_RS11415	COG0741	lytic transglycosylase activity
OFY20_RS11440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFY20_RS11445	COG0612	Peptidase, M16
OFY20_RS11450	COG0612	Peptidase, M16
OFY20_RS11455	COG2501	S4 domain
OFY20_RS11475	COG0517	IMP dehydrogenase activity
OFY20_RS11475	COG0516	GMP reductase activity
OFY20_RS11485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OFY20_RS11500	COG0454	-acetyltransferase
OFY20_RS11505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OFY20_RS11530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFY20_RS11535	COG0488	(ABC) transporter
OFY20_RS11540	COG4485	Bacterial membrane protein, YfhO
OFY20_RS11560	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OFY20_RS11565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFY20_RS11570	COG1475	DNA binding