locus-tag	class	description
SaSA73_RS00030	COG0012	GTP binding
SaSA73_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA73_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA73_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA73_RS00205	COG2801	Transposase and inactivated derivatives
SaSA73_RS00230	COG1695	Transcriptional regulator
SaSA73_RS00245	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA73_RS00280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA73_RS00315	COG1131	(ABC) transporter
SaSA73_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA73_RS00325	COG2190	(PTS) system
SaSA73_RS00325	COG1263	PTS System
SaSA73_RS00330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA73_RS00335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA73_RS00340	COG0275	rRNA processing
SaSA73_RS00350	COG0768	penicillin binding
SaSA73_RS00360	COG0513	Belongs to the DEAD box helicase family
SaSA73_RS00375	COG1126	abc transporter atp-binding protein
SaSA73_RS00385	COG0492	ferredoxin-NADP+ reductase activity
SaSA73_RS00390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA73_RS00435	COG0116	Belongs to the methyltransferase superfamily
SaSA73_RS00445	COG1854	S-ribosylhomocysteine lyase activity
SaSA73_RS00450	COG1418	mRNA catabolic process
SaSA73_RS00450	COG4372	Transposase
SaSA73_RS00460	COG1131	(ABC) transporter
SaSA73_RS00470	COG4585	Histidine kinase
SaSA73_RS00485	COG0194	GDP metabolic process
SaSA73_RS00495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA73_RS00500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA73_RS00505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA73_RS00505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA73_RS00515	COG0515	serine threonine protein kinase
SaSA73_RS00515	COG2815	serine threonine protein kinase
SaSA73_RS00525	COG4585	Histidine kinase
SaSA73_RS00530	COG2197	response regulator
SaSA73_RS00540	COG1098	S1 RNA binding domain
SaSA73_RS00550	COG1349	DNA-binding transcription factor activity
SaSA73_RS00560	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA73_RS00580	COG1739	Uncharacterized protein family UPF0029
SaSA73_RS00590	COG1040	competence protein
SaSA73_RS00625	COG0527	aspartate kinase activity
SaSA73_RS00640	COG1024	Enoyl-CoA hydratase
SaSA73_RS00650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA73_RS00660	COG2070	2-Nitropropane dioxygenase
SaSA73_RS00665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA73_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA73_RS00675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA73_RS00690	COG0439	Biotin carboxylase
SaSA73_RS00725	COG3716	PTS system mannose fructose sorbose family IID component
SaSA73_RS00730	COG3715	PTS system
SaSA73_RS00755	COG2252	PERMEase
SaSA73_RS00760	COG0802	atpase or kinase
SaSA73_RS00770	COG1316	TRANSCRIPTIONal
SaSA73_RS00780	COG0537	adenosine 5'-monophosphoramidase activity
SaSA73_RS00795	COG1131	(ABC) transporter
SaSA73_RS00800	COG4473	ABC transporter
SaSA73_RS00810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA73_RS00825	COG0195	Participates in both transcription termination and antitermination
SaSA73_RS00830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA73_RS00840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA73_RS00845	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA73_RS00870	COG2860	membrane
SaSA73_RS00880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA73_RS00880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA73_RS00885	COG1832	CoA-binding protein
SaSA73_RS00920	COG1268	BioY protein
SaSA73_RS00925	COG1234	tRNA 3'-trailer cleavage
SaSA73_RS00940	COG0166	Belongs to the GPI family
SaSA73_RS00945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA73_RS00950	COG0457	Tetratricopeptide repeat
SaSA73_RS00950	COG0705	Rhomboid family
SaSA73_RS00955	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA73_RS00960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA73_RS01080	COG0436	Aminotransferase
SaSA73_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA73_RS01110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA73_RS01115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA73_RS01130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA73_RS01170	COG0395	ABC-type sugar transport system, permease component
SaSA73_RS01185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA73_RS01210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA73_RS01230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA73_RS01245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA73_RS01260	COG1454	alcohol dehydrogenase
SaSA73_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
SaSA73_RS01265	COG1064	alcohol dehydrogenase
SaSA73_RS01275	COG0534	Mate efflux family protein
SaSA73_RS01385	COG0201	protein transport
SaSA73_RS01390	COG0563	adenylate kinase activity
SaSA73_RS01415	COG0202	RNA polymerase activity
SaSA73_RS01465	COG1121	(ABC) transporter
SaSA73_RS01470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA73_RS01480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA73_RS01485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA73_RS01485	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA73_RS01510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA73_RS01515	COG1459	type II secretion system
SaSA73_RS01560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SaSA73_RS01565	COG1363	Peptidase, m42
SaSA73_RS01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA73_RS01585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA73_RS01600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA73_RS01620	COG1346	cytolysis
SaSA73_RS01630	COG0601	transmembrane transport
SaSA73_RS01635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA73_RS01640	COG1122	ATPase activity
SaSA73_RS01660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA73_RS01680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SaSA73_RS01710	COG1045	serine acetyltransferase
SaSA73_RS01720	COG0215	cysteine-tRNA ligase activity
SaSA73_RS01725	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA73_RS01755	COG1476	TRANSCRIPTIONal
SaSA73_RS01760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA73_RS01805	COG1396	sequence-specific DNA binding
SaSA73_RS01820	COG1732	Glycine betaine
SaSA73_RS01950	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA73_RS01965	COG0443	Heat shock 70 kDa protein
SaSA73_RS01975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA73_RS01985	COG0351	phosphomethylpyrimidine kinase
SaSA73_RS01990	COG4720	Psort location CytoplasmicMembrane, score
SaSA73_RS02000	COG0668	transmembrane transport
SaSA73_RS02050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA73_RS02055	COG1879	ABC-type sugar transport system periplasmic component
SaSA73_RS02060	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA73_RS02075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA73_RS02080	COG1609	Transcriptional regulator
SaSA73_RS02090	COG0577	efflux transmembrane transporter activity
SaSA73_RS02095	COG1136	(ABC) transporter
SaSA73_RS02120	COG0191	fructose-bisphosphate aldolase activity
SaSA73_RS02140	COG1461	Dihydroxyacetone kinase
SaSA73_RS02160	COG1126	abc transporter atp-binding protein
SaSA73_RS02165	COG0765	amino acid transport
SaSA73_RS02185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA73_RS02195	COG0719	Fe-S assembly protein
SaSA73_RS02200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SaSA73_RS02210	COG0719	Fe-S assembly protein
SaSA73_RS02215	COG1686	Belongs to the peptidase S11 family
SaSA73_RS02220	COG1686	Belongs to the peptidase S11 family
SaSA73_RS02225	COG4166	transmembrane transport
SaSA73_RS02230	COG0601	transmembrane transport
SaSA73_RS02235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA73_RS02240	COG0444	Belongs to the ABC transporter superfamily
SaSA73_RS02245	COG4608	Belongs to the ABC transporter superfamily
SaSA73_RS02310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA73_RS02320	COG2153	protein acetylation
SaSA73_RS02330	COG1216	Glycosyl transferase, family 2
SaSA73_RS02330	COG1442	glycosyl transferase family 8
SaSA73_RS02390	COG0789	Transcriptional regulator
SaSA73_RS02395	COG1063	alcohol dehydrogenase
SaSA73_RS02400	COG0656	L-ascorbic acid biosynthetic process
SaSA73_RS02450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA73_RS02455	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA73_RS02460	COG3775	system Galactitol-specific IIC component
SaSA73_RS02465	COG0235	Class ii aldolase
SaSA73_RS02475	COG3775	system Galactitol-specific IIC component
SaSA73_RS02480	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA73_RS02485	COG2207	Transcriptional regulator
SaSA73_RS02495	COG1175	transmembrane transport
SaSA73_RS02500	COG0395	ABC-type sugar transport system, permease component
SaSA73_RS02520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA73_RS02590	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA73_RS02595	COG0673	inositol 2-dehydrogenase activity
SaSA73_RS02620	COG0742	ribosomal rna small subunit methyltransferase
SaSA73_RS02635	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA73_RS02645	COG4470	Protein conserved in bacteria
SaSA73_RS02660	COG1132	(ABC) transporter
SaSA73_RS02665	COG1132	(ABC) transporter
SaSA73_RS02670	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA73_RS02675	COG1268	BioY protein
SaSA73_RS02680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA73_RS02700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA73_RS02720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SaSA73_RS02725	COG1217	gtp-binding protein TYPA
SaSA73_RS02760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA73_RS02770	COG0762	integral membrane protein
SaSA73_RS02775	COG2302	S4 RNA-binding domain
SaSA73_RS02780	COG3599	regulation of cell shape
SaSA73_RS02800	COG0542	response to heat
SaSA73_RS02810	COG4703	Protein of unknown function (DUF1797)
SaSA73_RS02815	COG0765	amino acid transport
SaSA73_RS02820	COG1126	abc transporter atp-binding protein
SaSA73_RS02825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA73_RS02835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA73_RS02840	COG1570	exodeoxyribonuclease VII activity
SaSA73_RS02845	COG1722	exodeoxyribonuclease VII activity
SaSA73_RS02855	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA73_RS02860	COG1438	arginine binding
SaSA73_RS02865	COG0497	DNA recombination
SaSA73_RS02870	COG1307	EDD domain protein, DegV family
SaSA73_RS02875	COG2755	lipolytic protein G-D-S-L family
SaSA73_RS02920	COG1078	dGTPase activity
SaSA73_RS02945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA73_RS02955	COG2884	Cell division ATP-binding protein ftsE
SaSA73_RS02960	COG2177	Part of the ABC transporter FtsEX involved in
SaSA73_RS02980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA73_RS02980	COG1199	ATP-dependent helicase activity
SaSA73_RS02985	COG0436	Aminotransferase
SaSA73_RS02990	COG0017	Asparaginyl-tRNA synthetase
SaSA73_RS03015	COG1660	Displays ATPase and GTPase activities
SaSA73_RS03040	COG0254	rRNA binding
SaSA73_RS03045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA73_RS03050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA73_RS03055	COG0716	FMN binding
SaSA73_RS03060	COG1605	Chorismate mutase
SaSA73_RS03060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA73_RS03070	COG0335	large ribosomal subunit rRNA binding
SaSA73_RS03080	COG0772	Belongs to the SEDS family
SaSA73_RS03100	COG0560	Phosphoserine phosphatase
SaSA73_RS03115	COG0148	phosphopyruvate hydratase activity
SaSA73_RS03135	COG1316	TRANSCRIPTIONal
SaSA73_RS03230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA73_RS03235	COG4555	ABC transporter
SaSA73_RS03285	COG3590	peptidase
SaSA73_RS03330	COG1136	(ABC) transporter
SaSA73_RS03345	COG0586	Pfam SNARE associated Golgi protein
SaSA73_RS03350	COG4619	ABC transporter
SaSA73_RS03355	COG0390	transport system, permease component
SaSA73_RS03365	COG0583	DNA-binding transcription factor activity
SaSA73_RS03375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA73_RS03380	COG2211	Major facilitator Superfamily
SaSA73_RS03385	COG3250	beta-galactosidase activity
SaSA73_RS03390	COG2186	Transcriptional regulator
SaSA73_RS03405	COG1904	glucuronate isomerase
SaSA73_RS03410	COG1312	Catalyzes the dehydration of D-mannonate
SaSA73_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA73_RS03435	COG1609	Transcriptional regulator
SaSA73_RS03475	COG0765	amino acid transport
SaSA73_RS03480	COG0765	amino acid transport
SaSA73_RS03490	COG1126	abc transporter atp-binding protein
SaSA73_RS03495	COG0745	RESPONSE REGULATOR receiver
SaSA73_RS03500	COG5002	protein histidine kinase activity
SaSA73_RS03505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA73_RS03510	COG2832	Protein of unknown function (DUF454)
SaSA73_RS03525	COG0561	phosphatase activity
SaSA73_RS03530	COG0561	phosphatase activity
SaSA73_RS03535	COG0552	protein localization to endoplasmic reticulum
SaSA73_RS03540	COG3689	TIGRFAM TIGR03943 family protein
SaSA73_RS03545	COG0701	Predicted permease
SaSA73_RS03560	COG2183	response to ionizing radiation
SaSA73_RS03565	COG3091	SprT-like family
SaSA73_RS03570	COG1983	PspC domain protein
SaSA73_RS03615	COG0826	peptidase U32
SaSA73_RS03620	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA73_RS03630	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA73_RS03645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA73_RS03645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA73_RS03670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA73_RS03705	COG0772	Belongs to the SEDS family
SaSA73_RS03725	COG0768	penicillin binding
SaSA73_RS03740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA73_RS03745	COG2223	nitrite transmembrane transporter activity
SaSA73_RS03770	COG2011	ABC-type metal ion transport system permease component
SaSA73_RS03775	COG1464	Belongs to the NlpA lipoprotein family
SaSA73_RS03780	COG0513	Belongs to the DEAD box helicase family
SaSA73_RS03790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA73_RS03795	COG0204	Acyl-transferase
SaSA73_RS03800	COG1555	photosystem II stabilization
SaSA73_RS03800	COG1596	polysaccharide export
SaSA73_RS03825	COG0657	acetylesterase activity
SaSA73_RS03830	COG2226	methyltransferase
SaSA73_RS03840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA73_RS03845	COG3711	transcriptional antiterminator
SaSA73_RS03865	COG3835	regulator
SaSA73_RS03870	COG1929	Belongs to the glycerate kinase type-1 family
SaSA73_RS03875	COG2610	gluconate transmembrane transporter activity
SaSA73_RS03890	COG1846	Transcriptional regulator
SaSA73_RS03895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA73_RS03910	COG0435	Glutathione S-transferase
SaSA73_RS03915	COG1187	pseudouridine synthase activity
SaSA73_RS03940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA73_RS03945	COG4122	O-methyltransferase activity
SaSA73_RS03955	COG4894	glucomannan catabolic process
SaSA73_RS03960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA73_RS03965	COG1811	Na channel or pump
SaSA73_RS03970	COG1442	glycosyl transferase family 8
SaSA73_RS03985	COG1476	TRANSCRIPTIONal
SaSA73_RS04000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA73_RS04005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA73_RS04010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA73_RS04025	COG1012	belongs to the aldehyde dehydrogenase family
SaSA73_RS04030	COG0726	polysaccharide deacetylase
SaSA73_RS04040	COG0513	Belongs to the DEAD box helicase family
SaSA73_RS04050	COG1956	GAF domain-containing protein
SaSA73_RS04055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA73_RS04065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SaSA73_RS04065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SaSA73_RS04070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA73_RS04100	COG4721	ABC-type cobalt transport system, permease component
SaSA73_RS04105	COG1122	ATPase activity
SaSA73_RS04115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA73_RS04125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA73_RS04130	COG0352	thiamine-phosphate diphosphorylase activity
SaSA73_RS04135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA73_RS04150	COG0024	Methionine aminopeptidase
SaSA73_RS04165	COG4708	membrane
SaSA73_RS04170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA73_RS04175	COG1597	lipid kinase activity
SaSA73_RS04180	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA73_RS04195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SaSA73_RS04210	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA73_RS04235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SaSA73_RS04240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA73_RS04250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA73_RS04275	COG0072	phenylalanine-tRNA ligase activity
SaSA73_RS04275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA73_RS04280	COG2321	neutral zinc metallopeptidase
SaSA73_RS04290	COG1074	ATP-dependent DNA helicase activity
SaSA73_RS04300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA73_RS04305	COG0488	(ABC) transporter
SaSA73_RS04310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA73_RS04315	COG0022	dehydrogenase e1 component
SaSA73_RS04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA73_RS04330	COG0095	Lipoate-protein ligase
SaSA73_RS04335	COG3442	glutamine amidotransferase
SaSA73_RS04340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA73_RS04345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA73_RS04370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA73_RS04390	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA73_RS04395	COG1518	maintenance of DNA repeat elements
SaSA73_RS04400	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA73_RS04420	COG0481	GTPase activity
SaSA73_RS04470	COG1131	(ABC) transporter
SaSA73_RS04475	COG1725	Transcriptional regulator
SaSA73_RS04485	COG0205	6-phosphofructokinase activity
SaSA73_RS04490	COG0469	pyruvate kinase activity
SaSA73_RS04495	COG0681	Belongs to the peptidase S26 family
SaSA73_RS04505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA73_RS04510	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA73_RS04515	COG0765	amino acid transport
SaSA73_RS04520	COG1126	abc transporter atp-binding protein
SaSA73_RS04540	COG1072	(Pantothenic acid kinase))
SaSA73_RS04550	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA73_RS04565	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA73_RS04585	COG3764	Sortase (surface protein transpeptidase)
SaSA73_RS04590	COG0346	lactoylglutathione lyase activity
SaSA73_RS04610	COG2188	Transcriptional regulator
SaSA73_RS04615	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA73_RS04625	COG1464	Belongs to the NlpA lipoprotein family
SaSA73_RS04640	COG1136	(ABC) transporter
SaSA73_RS04650	COG0745	RESPONSE REGULATOR receiver
SaSA73_RS04655	COG5002	protein histidine kinase activity
SaSA73_RS04660	COG4974	Belongs to the 'phage' integrase family
SaSA73_RS04680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA73_RS04685	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SaSA73_RS04690	COG5002	protein histidine kinase activity
SaSA73_RS04705	COG0704	Plays a role in the regulation of phosphate uptake
SaSA73_RS04710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA73_RS04715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA73_RS04720	COG0581	inorganic phosphate transmembrane transporter activity
SaSA73_RS04725	COG0573	inorganic phosphate transmembrane transporter activity
SaSA73_RS04745	COG4476	Belongs to the UPF0223 family
SaSA73_RS04755	COG0196	riboflavin kinase activity
SaSA73_RS04760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SaSA73_RS04790	COG1136	(ABC) transporter
SaSA73_RS04795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA73_RS04800	COG0758	DNA mediated transformation
SaSA73_RS04805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA73_RS04810	COG4604	ABC transporter, ATP-binding protein
SaSA73_RS04815	COG4605	iron ion homeostasis
SaSA73_RS04820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA73_RS04825	COG0110	maltose O-acetyltransferase activity
SaSA73_RS04835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA73_RS04840	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA73_RS04845	COG1966	Carbon starvation protein
SaSA73_RS04850	COG3279	Response regulator of the LytR AlgR family
SaSA73_RS04855	COG3275	phosphorelay sensor kinase activity
SaSA73_RS04905	COG0505	Belongs to the CarA family
SaSA73_RS04920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA73_RS04935	COG0488	(ABC) transporter
SaSA73_RS04945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA73_RS04960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA73_RS05010	COG0095	Lipoate-protein ligase
SaSA73_RS05020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA73_RS05025	COG4684	Psort location CytoplasmicMembrane, score
SaSA73_RS05030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA73_RS05070	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA73_RS05085	COG1942	4-Oxalocrotonate Tautomerase
SaSA73_RS05105	COG3976	FMN-binding domain protein
SaSA73_RS05105	COG1053	succinate dehydrogenase
SaSA73_RS05105	COG0431	NADPH-dependent FMN reductase
SaSA73_RS05115	COG2233	PERMEase
SaSA73_RS05130	COG0477	Major facilitator Superfamily
SaSA73_RS05145	COG4221	oxidoreductase activity
SaSA73_RS05155	COG0564	pseudouridine synthase activity
SaSA73_RS05160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA73_RS05165	COG2357	RelA SpoT domain protein
SaSA73_RS05180	COG1104	cysteine desulfurase activity
SaSA73_RS05200	COG0628	permease
SaSA73_RS05215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA73_RS05290	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA73_RS05300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA73_RS05305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA73_RS05325	COG0285	dihydrofolate synthase activity
SaSA73_RS05330	COG2962	Rard protein
SaSA73_RS05350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA73_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
SaSA73_RS05445	COG2261	transglycosylase associated protein
SaSA73_RS05470	COG1115	amino acid carrier protein
SaSA73_RS05475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA73_RS05485	COG1346	cytolysis
SaSA73_RS05500	COG0539	negative regulation of cytoplasmic translation
SaSA73_RS05520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA73_RS05530	COG0187	DNA topoisomerase II activity
SaSA73_RS05535	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA73_RS05545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA73_RS05555	COG2755	lipolytic protein G-D-S-L family
SaSA73_RS05555	COG1083	cytidylyl-transferase
SaSA73_RS05605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA73_RS05610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA73_RS05630	COG1316	TRANSCRIPTIONal
SaSA73_RS05670	COG3842	ATPase activity
SaSA73_RS05690	COG3527	Alpha-acetolactate decarboxylase
SaSA73_RS05695	COG0028	Belongs to the TPP enzyme family
SaSA73_RS05700	COG0457	Tetratricopeptide repeat
SaSA73_RS05705	COG0628	permease
SaSA73_RS05715	COG1051	belongs to the nudix hydrolase family
SaSA73_RS05720	COG5492	domain, Protein
SaSA73_RS05725	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA73_RS05735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA73_RS05740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA73_RS05780	COG0300	oxidoreductase activity
SaSA73_RS05800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA73_RS05830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA73_RS05840	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA73_RS05855	COG0534	Mate efflux family protein
SaSA73_RS05910	COG2040	homocysteine
SaSA73_RS05915	COG0833	amino acid
SaSA73_RS05955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA73_RS05965	COG3425	synthase
SaSA73_RS05980	COG1272	protein, Hemolysin III
SaSA73_RS06025	COG0745	RESPONSE REGULATOR receiver
SaSA73_RS06030	COG2357	RelA SpoT domain protein
SaSA73_RS06045	COG1132	(ABC) transporter
SaSA73_RS06060	COG0488	(ABC) transporter
SaSA73_RS06090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA73_RS06090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA73_RS06090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA73_RS06095	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA73_RS06155	COG1837	Belongs to the UPF0109 family
SaSA73_RS06160	COG0228	four-way junction DNA binding
SaSA73_RS06165	COG0577	efflux transmembrane transporter activity
SaSA73_RS06170	COG1136	(ABC) transporter
SaSA73_RS06195	COG0564	pseudouridine synthase activity
SaSA73_RS06205	COG0583	DNA-binding transcription factor activity
SaSA73_RS06210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA73_RS06230	COG0301	tRNA thio-modification
SaSA73_RS06235	COG1104	cysteine desulfurase activity
SaSA73_RS06245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA73_RS06265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaSA73_RS06270	COG1368	sulfuric ester hydrolase activity
SaSA73_RS06280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA73_RS06290	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA73_RS06320	COG2244	polysaccharide biosynthetic process
SaSA73_RS06325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA73_RS06330	COG1120	ATPase activity
SaSA73_RS06335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaSA73_RS06365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA73_RS06370	COG1253	flavin adenine dinucleotide binding
SaSA73_RS06375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA73_RS06380	COG1242	4 iron, 4 sulfur cluster binding
SaSA73_RS06385	COG0671	phosphoesterase, PA-phosphatase related
SaSA73_RS06390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA73_RS06435	COG0297	glycogen (starch) synthase activity
SaSA73_RS06490	COG0463	Glycosyl transferase, family 2
SaSA73_RS06495	COG1215	transferase activity, transferring glycosyl groups
SaSA73_RS06505	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA73_RS06510	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA73_RS06515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA73_RS06520	COG0358	DNA primase activity
SaSA73_RS06525	COG1970	mechanosensitive ion channel activity
SaSA73_RS06540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA73_RS06545	COG0004	ammonium transporteR
SaSA73_RS06555	COG1054	Belongs to the UPF0176 family
SaSA73_RS06575	COG0058	SHG alpha-glucan phosphorylase activity
SaSA73_RS06580	COG1640	4-alpha-glucanotransferase
SaSA73_RS06585	COG1609	Transcriptional regulator
SaSA73_RS06595	COG1175	transmembrane transport
SaSA73_RS06600	COG3833	ABC-type maltose transport systems, permease component
SaSA73_RS06635	COG0438	transferase activity, transferring glycosyl groups
SaSA73_RS06685	COG0765	amino acid transport
SaSA73_RS06690	COG1126	abc transporter atp-binding protein
SaSA73_RS06715	COG2309	aminopeptidase activity
SaSA73_RS06730	COG1187	pseudouridine synthase activity
SaSA73_RS06735	COG0656	L-ascorbic acid biosynthetic process
SaSA73_RS06740	COG0778	Nitroreductase
SaSA73_RS06745	COG0346	lactoylglutathione lyase activity
SaSA73_RS06755	COG1113	amino acid transport
SaSA73_RS06760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SaSA73_RS06790	COG1131	(ABC) transporter
SaSA73_RS06800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA73_RS06860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SaSA73_RS06865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SaSA73_RS06895	COG1702	phosphate starvation-inducible protein PhoH
SaSA73_RS06920	COG0233	cytoplasmic translational termination
SaSA73_RS06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA73_RS06940	COG0601	transmembrane transport
SaSA73_RS06945	COG0747	negative chemotaxis
SaSA73_RS06950	COG0081	regulation of translation
SaSA73_RS06955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA73_RS06965	COG1473	amidohydrolase
SaSA73_RS06970	COG0583	DNA-binding transcription factor activity
SaSA73_RS06985	COG1674	ftsk spoiiie
SaSA73_RS06990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA73_RS07015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA73_RS07050	COG0673	inositol 2-dehydrogenase activity
SaSA73_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA73_RS07115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA73_RS07115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA73_RS07135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA73_RS07145	COG0708	Exodeoxyribonuclease III
SaSA73_RS07150	COG1393	Belongs to the ArsC family
SaSA73_RS07155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA73_RS07160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA73_RS07170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA73_RS07195	COG0470	DNA polymerase III
SaSA73_RS07205	COG0517	IMP dehydrogenase activity
SaSA73_RS07225	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA73_RS07245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA73_RS07250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA73_RS07260	COG0531	amino acid
SaSA73_RS07265	COG0569	domain protein
SaSA73_RS07285	COG1187	pseudouridine synthase activity
SaSA73_RS07320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA73_RS07335	COG1827	regulation of RNA biosynthetic process
SaSA73_RS07350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA73_RS07355	COG1254	Belongs to the acylphosphatase family
SaSA73_RS07365	COG0765	amino acid transport
SaSA73_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA73_RS07385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA73_RS07410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA73_RS07420	COG1484	DNA-dependent DNA replication
SaSA73_RS07440	COG0745	RESPONSE REGULATOR receiver
SaSA73_RS07450	COG0501	Belongs to the peptidase M48B family
SaSA73_RS07455	COG1704	LemA family
SaSA73_RS07460	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA73_RS07465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA73_RS07470	COG0569	domain protein
SaSA73_RS07495	COG1114	Component of the transport system for branched-chain amino acids
SaSA73_RS07500	COG1063	alcohol dehydrogenase
SaSA73_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA73_RS07530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA73_RS07540	COG0217	transcriptional regulatory protein
SaSA73_RS07550	COG2376	Dihydroxyacetone kinase
SaSA73_RS07555	COG1309	transcriptional regulator
SaSA73_RS07565	COG2376	Dihydroxyacetone kinase
SaSA73_RS07575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA73_RS07580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA73_RS07590	COG0789	Transcriptional regulator
SaSA73_RS07605	COG2226	methyltransferase
SaSA73_RS07620	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA73_RS07625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA73_RS07630	COG1534	Rna-binding protein
SaSA73_RS07635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA73_RS07655	COG0154	amidase activity
SaSA73_RS07660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA73_RS07665	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA73_RS07665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA73_RS07675	COG0517	IMP dehydrogenase activity
SaSA73_RS07680	COG1250	3-hydroxyacyl-CoA dehydrogenase
SaSA73_RS07680	COG1024	Enoyl-CoA hydratase
SaSA73_RS07685	COG1335	isochorismatase
SaSA73_RS07690	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA73_RS07695	COG0436	Aminotransferase
SaSA73_RS07700	COG0589	response to stress
SaSA73_RS07710	COG0252	asparaginase activity
SaSA73_RS07720	COG4989	oxidoreductase activity
SaSA73_RS07725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA73_RS07730	COG3942	CHAP domain
SaSA73_RS07730	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA73_RS07740	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA73_RS07755	COG1482	cell wall glycoprotein biosynthetic process
SaSA73_RS07760	COG1940	carbohydrate kinase activity
SaSA73_RS07765	COG2190	(PTS) system
SaSA73_RS07765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA73_RS07765	COG1263	PTS System
SaSA73_RS07770	COG1621	beta-fructofuranosidase activity
SaSA73_RS07775	COG1609	Transcriptional regulator
SaSA73_RS07790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA73_RS07825	COG2131	deaminase
SaSA73_RS07830	COG0006	proline dipeptidase activity
SaSA73_RS07840	COG2814	Major facilitator Superfamily
SaSA73_RS07865	COG0629	single-stranded DNA binding
SaSA73_RS07870	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA73_RS07875	COG1194	a g-specific adenine glycosylase
SaSA73_RS07885	COG3118	belongs to the thioredoxin family
SaSA73_RS07910	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA73_RS07915	COG0681	Belongs to the peptidase S26 family
SaSA73_RS07920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA73_RS07935	COG1882	Formate acetyltransferase
SaSA73_RS07945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA73_RS07960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA73_RS07970	COG2814	Major facilitator Superfamily
SaSA73_RS07975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA73_RS07995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA73_RS08000	COG4988	ABC transporter
SaSA73_RS08005	COG1294	oxidase, subunit
SaSA73_RS08015	COG1252	NADH dehydrogenase
SaSA73_RS08040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA73_RS08095	COG1214	PFAM Peptidase M22, glycoprotease
SaSA73_RS08110	COG3942	CHAP domain
SaSA73_RS08115	COG0174	glutamine synthetase
SaSA73_RS08120	COG0789	Transcriptional regulator
SaSA73_RS08135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA73_RS08165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA73_RS08190	COG1162	GTPase activity
SaSA73_RS08210	COG0693	protein deglycase activity
SaSA73_RS08245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA73_RS08250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA73_RS08255	COG1696	Membrane protein involved in D-alanine export
SaSA73_RS08285	COG3314	Sporulation integral membrane protein YlbJ
SaSA73_RS08295	COG4175	Glycine betaine
SaSA73_RS08295	COG3448	diguanylate cyclase activity
SaSA73_RS08305	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SaSA73_RS08335	COG3775	system Galactitol-specific IIC component
SaSA73_RS08400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA73_RS08435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA73_RS08440	COG1428	Deoxynucleoside kinase
SaSA73_RS08450	COG0542	response to heat
SaSA73_RS08455	COG4463	regulation of RNA biosynthetic process
SaSA73_RS08465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA73_RS08490	COG0025	NhaP-type Na H and K H
SaSA73_RS08500	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA73_RS08505	COG3590	peptidase
SaSA73_RS08535	COG1609	Transcriptional regulator
SaSA73_RS08545	COG3716	PTS system mannose fructose sorbose family IID component
SaSA73_RS08555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA73_RS08560	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA73_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA73_RS08615	COG2176	DNA-directed DNA polymerase activity
SaSA73_RS08640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SaSA73_RS08645	COG1862	Preprotein translocase
SaSA73_RS08665	COG3290	protein histidine kinase activity
SaSA73_RS08675	COG4565	transcriptional regulatory protein
SaSA73_RS08680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA73_RS08690	COG3842	ATPase activity
SaSA73_RS08765	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA73_RS08775	COG0737	Belongs to the 5'-nucleotidase family
SaSA73_RS08790	COG1363	Peptidase, m42
SaSA73_RS08810	COG2972	Histidine kinase
SaSA73_RS08815	COG3716	PTS system mannose fructose sorbose family IID component
SaSA73_RS08820	COG3715	PTS system
SaSA73_RS08850	COG1131	(ABC) transporter
SaSA73_RS08870	COG3290	protein histidine kinase activity
SaSA73_RS08890	COG2190	(PTS) system
SaSA73_RS08890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA73_RS08890	COG1263	PTS System
SaSA73_RS08910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA73_RS08915	COG0581	inorganic phosphate transmembrane transporter activity
SaSA73_RS08935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA73_RS08950	COG0789	Transcriptional regulator
SaSA73_RS08985	COG0456	acetyltransferase
SaSA73_RS08990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA73_RS09065	COG1131	(ABC) transporter
SaSA73_RS09075	COG1396	sequence-specific DNA binding
SaSA73_RS09095	COG2897	thiosulfate sulfurtransferase activity
SaSA73_RS09115	COG0371	Dehydrogenase
SaSA73_RS09140	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA73_RS09155	COG0745	RESPONSE REGULATOR receiver
SaSA73_RS09170	COG0495	leucyl-tRNA aminoacylation
SaSA73_RS09180	COG2814	Major facilitator Superfamily
SaSA73_RS09185	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA73_RS09235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA73_RS09240	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA73_RS09260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA73_RS09265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA73_RS09265	COG1116	anion transmembrane transporter activity
SaSA73_RS09275	COG0561	phosphatase activity
SaSA73_RS09280	COG2514	catechol 2,3-dioxygenase activity
SaSA73_RS09290	COG0602	queuosine metabolic process
SaSA73_RS09310	COG1328	CTP reductase activity
SaSA73_RS09330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA73_RS09340	COG1393	Belongs to the ArsC family
SaSA73_RS09345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA73_RS09350	COG1058	Belongs to the CinA family
SaSA73_RS09350	COG1546	Belongs to the CinA family
SaSA73_RS09355	COG2818	Glycosylase
SaSA73_RS09395	COG0018	arginyl-trna synthetase
SaSA73_RS09405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA73_RS09410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA73_RS09420	COG0124	histidyl-tRNA synthetase
SaSA73_RS09430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA73_RS09465	COG1174	glycine betaine transport
SaSA73_RS09475	COG0392	lysyltransferase activity
SaSA73_RS09475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA73_RS09515	COG0305	Participates in initiation and elongation during chromosome replication
SaSA73_RS09540	COG0482	sulfurtransferase activity
SaSA73_RS09545	COG1760	l-serine dehydratase
SaSA73_RS09550	COG1760	l-serine dehydratase
SaSA73_RS09555	COG0741	lytic transglycosylase activity
SaSA73_RS09580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA73_RS09585	COG0612	Peptidase, M16
SaSA73_RS09590	COG0612	Peptidase, M16
SaSA73_RS09595	COG2501	S4 domain
SaSA73_RS09615	COG0516	GMP reductase activity
SaSA73_RS09615	COG0517	IMP dehydrogenase activity
SaSA73_RS09640	COG0454	-acetyltransferase
SaSA73_RS09645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA73_RS09655	COG0549	Belongs to the carbamate kinase family
SaSA73_RS09675	COG0488	(ABC) transporter
SaSA73_RS09680	COG4485	Bacterial membrane protein, YfhO
SaSA73_RS09700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA73_RS09705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA73_RS09710	COG1475	DNA binding