locus-tag	class	description
SaSA85_RS00010	COG0592	DNA-directed DNA polymerase activity
SaSA85_RS00030	COG0012	GTP binding
SaSA85_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA85_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA85_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA85_RS00205	COG2801	Transposase and inactivated derivatives
SaSA85_RS00230	COG1695	Transcriptional regulator
SaSA85_RS00245	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA85_RS00280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA85_RS00315	COG1131	(ABC) transporter
SaSA85_RS00325	COG1263	PTS System
SaSA85_RS00325	COG2190	(PTS) system
SaSA85_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA85_RS00330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SaSA85_RS00340	COG0275	rRNA processing
SaSA85_RS00350	COG0768	penicillin binding
SaSA85_RS00360	COG0513	Belongs to the DEAD box helicase family
SaSA85_RS00375	COG1126	abc transporter atp-binding protein
SaSA85_RS00385	COG0492	ferredoxin-NADP+ reductase activity
SaSA85_RS00390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA85_RS00435	COG0116	Belongs to the methyltransferase superfamily
SaSA85_RS00445	COG1854	S-ribosylhomocysteine lyase activity
SaSA85_RS00450	COG1418	mRNA catabolic process
SaSA85_RS00450	COG4372	Transposase
SaSA85_RS00460	COG1131	(ABC) transporter
SaSA85_RS00470	COG4585	Histidine kinase
SaSA85_RS00485	COG0194	GDP metabolic process
SaSA85_RS00495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA85_RS00500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SaSA85_RS00515	COG0515	serine threonine protein kinase
SaSA85_RS00515	COG2815	serine threonine protein kinase
SaSA85_RS00525	COG4585	Histidine kinase
SaSA85_RS00530	COG2197	response regulator
SaSA85_RS00540	COG1098	S1 RNA binding domain
SaSA85_RS00550	COG1349	DNA-binding transcription factor activity
SaSA85_RS00560	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA85_RS00580	COG1739	Uncharacterized protein family UPF0029
SaSA85_RS00585	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaSA85_RS00590	COG1040	competence protein
SaSA85_RS00625	COG0527	aspartate kinase activity
SaSA85_RS00630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA85_RS00640	COG1024	Enoyl-CoA hydratase
SaSA85_RS00650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SaSA85_RS00660	COG2070	2-Nitropropane dioxygenase
SaSA85_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA85_RS00675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA85_RS00690	COG0439	Biotin carboxylase
SaSA85_RS00710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SaSA85_RS00725	COG3716	PTS system mannose fructose sorbose family IID component
SaSA85_RS00730	COG3715	PTS system
SaSA85_RS00745	COG0561	phosphatase activity
SaSA85_RS00760	COG2252	PERMEase
SaSA85_RS00765	COG0802	atpase or kinase
SaSA85_RS00775	COG1316	TRANSCRIPTIONal
SaSA85_RS00785	COG0537	adenosine 5'-monophosphoramidase activity
SaSA85_RS00800	COG1131	(ABC) transporter
SaSA85_RS00805	COG4473	ABC transporter
SaSA85_RS00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SaSA85_RS00830	COG0195	Participates in both transcription termination and antitermination
SaSA85_RS00835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA85_RS00845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SaSA85_RS00850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SaSA85_RS00875	COG2860	membrane
SaSA85_RS00885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA85_RS00885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA85_RS00890	COG1832	CoA-binding protein
SaSA85_RS00925	COG1268	BioY protein
SaSA85_RS00930	COG1234	tRNA 3'-trailer cleavage
SaSA85_RS00945	COG0166	Belongs to the GPI family
SaSA85_RS00950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA85_RS00955	COG0705	Rhomboid family
SaSA85_RS00955	COG0457	Tetratricopeptide repeat
SaSA85_RS00960	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA85_RS01085	COG0436	Aminotransferase
SaSA85_RS01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA85_RS01115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA85_RS01120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA85_RS01135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA85_RS01175	COG0395	ABC-type sugar transport system, permease component
SaSA85_RS01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA85_RS01215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA85_RS01235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA85_RS01250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA85_RS01260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA85_RS01260	COG2755	lipolytic protein G-D-S-L family
SaSA85_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
SaSA85_RS01265	COG1454	alcohol dehydrogenase
SaSA85_RS01270	COG1064	alcohol dehydrogenase
SaSA85_RS01280	COG0534	Mate efflux family protein
SaSA85_RS01390	COG0201	protein transport
SaSA85_RS01395	COG0563	adenylate kinase activity
SaSA85_RS01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SaSA85_RS01420	COG0202	RNA polymerase activity
SaSA85_RS01470	COG1121	(ABC) transporter
SaSA85_RS01475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA85_RS01485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA85_RS01490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA85_RS01490	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA85_RS01520	COG1459	type II secretion system
SaSA85_RS01570	COG1363	Peptidase, m42
SaSA85_RS01585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA85_RS01590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA85_RS01605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA85_RS01625	COG1346	cytolysis
SaSA85_RS01635	COG0601	transmembrane transport
SaSA85_RS01640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA85_RS01645	COG1122	ATPase activity
SaSA85_RS01665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA85_RS01685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SaSA85_RS01715	COG1045	serine acetyltransferase
SaSA85_RS01725	COG0215	cysteine-tRNA ligase activity
SaSA85_RS01730	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA85_RS01760	COG1476	TRANSCRIPTIONal
SaSA85_RS01765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA85_RS01810	COG1396	sequence-specific DNA binding
SaSA85_RS01825	COG1732	Glycine betaine
SaSA85_RS01970	COG0443	Heat shock 70 kDa protein
SaSA85_RS01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA85_RS01990	COG0351	phosphomethylpyrimidine kinase
SaSA85_RS01995	COG4720	Psort location CytoplasmicMembrane, score
SaSA85_RS02005	COG0668	transmembrane transport
SaSA85_RS02035	COG0756	dUTP diphosphatase activity
SaSA85_RS02050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA85_RS02055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA85_RS02065	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA85_RS02080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA85_RS02085	COG1609	Transcriptional regulator
SaSA85_RS02095	COG0577	efflux transmembrane transporter activity
SaSA85_RS02100	COG1136	(ABC) transporter
SaSA85_RS02125	COG0191	fructose-bisphosphate aldolase activity
SaSA85_RS02145	COG1461	Dihydroxyacetone kinase
SaSA85_RS02165	COG1126	abc transporter atp-binding protein
SaSA85_RS02170	COG0765	amino acid transport
SaSA85_RS02190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA85_RS02200	COG0719	Fe-S assembly protein
SaSA85_RS02215	COG0719	Fe-S assembly protein
SaSA85_RS02220	COG1686	Belongs to the peptidase S11 family
SaSA85_RS02225	COG1686	Belongs to the peptidase S11 family
SaSA85_RS02230	COG4166	transmembrane transport
SaSA85_RS02235	COG0601	transmembrane transport
SaSA85_RS02240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA85_RS02245	COG0444	Belongs to the ABC transporter superfamily
SaSA85_RS02250	COG4608	Belongs to the ABC transporter superfamily
SaSA85_RS02310	COG2137	regulation of response to DNA damage stimulus
SaSA85_RS02315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA85_RS02325	COG2153	protein acetylation
SaSA85_RS02335	COG1216	Glycosyl transferase, family 2
SaSA85_RS02335	COG1442	glycosyl transferase family 8
SaSA85_RS02395	COG0789	Transcriptional regulator
SaSA85_RS02400	COG1063	alcohol dehydrogenase
SaSA85_RS02405	COG0656	L-ascorbic acid biosynthetic process
SaSA85_RS02455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA85_RS02460	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA85_RS02465	COG3775	system Galactitol-specific IIC component
SaSA85_RS02470	COG0235	Class ii aldolase
SaSA85_RS02480	COG3775	system Galactitol-specific IIC component
SaSA85_RS02485	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA85_RS02490	COG2207	Transcriptional regulator
SaSA85_RS02500	COG1175	transmembrane transport
SaSA85_RS02505	COG0395	ABC-type sugar transport system, permease component
SaSA85_RS02525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA85_RS02595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA85_RS02600	COG0673	inositol 2-dehydrogenase activity
SaSA85_RS02625	COG0742	ribosomal rna small subunit methyltransferase
SaSA85_RS02640	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA85_RS02650	COG4470	Protein conserved in bacteria
SaSA85_RS02665	COG1132	(ABC) transporter
SaSA85_RS02670	COG1132	(ABC) transporter
SaSA85_RS02675	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA85_RS02680	COG1268	BioY protein
SaSA85_RS02685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA85_RS02705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA85_RS02725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SaSA85_RS02730	COG1217	gtp-binding protein TYPA
SaSA85_RS02765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA85_RS02775	COG0762	integral membrane protein
SaSA85_RS02780	COG2302	S4 RNA-binding domain
SaSA85_RS02785	COG3599	regulation of cell shape
SaSA85_RS02805	COG0542	response to heat
SaSA85_RS02815	COG4703	Protein of unknown function (DUF1797)
SaSA85_RS02820	COG0765	amino acid transport
SaSA85_RS02825	COG1126	abc transporter atp-binding protein
SaSA85_RS02830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA85_RS02840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA85_RS02845	COG1570	exodeoxyribonuclease VII activity
SaSA85_RS02850	COG1722	exodeoxyribonuclease VII activity
SaSA85_RS02860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA85_RS02865	COG1438	arginine binding
SaSA85_RS02870	COG0497	DNA recombination
SaSA85_RS02875	COG1307	EDD domain protein, DegV family
SaSA85_RS02880	COG2755	lipolytic protein G-D-S-L family
SaSA85_RS02925	COG1078	dGTPase activity
SaSA85_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA85_RS02960	COG2884	Cell division ATP-binding protein ftsE
SaSA85_RS02965	COG2177	Part of the ABC transporter FtsEX involved in
SaSA85_RS02985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA85_RS02985	COG1199	ATP-dependent helicase activity
SaSA85_RS02990	COG0436	Aminotransferase
SaSA85_RS02995	COG0017	Asparaginyl-tRNA synthetase
SaSA85_RS03020	COG1660	Displays ATPase and GTPase activities
SaSA85_RS03045	COG0254	rRNA binding
SaSA85_RS03050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA85_RS03055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA85_RS03060	COG0716	FMN binding
SaSA85_RS03065	COG1605	Chorismate mutase
SaSA85_RS03065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA85_RS03075	COG0335	large ribosomal subunit rRNA binding
SaSA85_RS03085	COG0772	Belongs to the SEDS family
SaSA85_RS03105	COG0560	Phosphoserine phosphatase
SaSA85_RS03120	COG0148	phosphopyruvate hydratase activity
SaSA85_RS03140	COG1316	TRANSCRIPTIONal
SaSA85_RS03235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA85_RS03240	COG4555	ABC transporter
SaSA85_RS03330	COG1136	(ABC) transporter
SaSA85_RS03345	COG0586	Pfam SNARE associated Golgi protein
SaSA85_RS03350	COG4619	ABC transporter
SaSA85_RS03355	COG0390	transport system, permease component
SaSA85_RS03365	COG0583	DNA-binding transcription factor activity
SaSA85_RS03375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA85_RS03380	COG2211	Major facilitator Superfamily
SaSA85_RS03385	COG3250	beta-galactosidase activity
SaSA85_RS03390	COG2186	Transcriptional regulator
SaSA85_RS03405	COG1904	glucuronate isomerase
SaSA85_RS03410	COG1312	Catalyzes the dehydration of D-mannonate
SaSA85_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA85_RS03435	COG1609	Transcriptional regulator
SaSA85_RS03475	COG0765	amino acid transport
SaSA85_RS03480	COG0765	amino acid transport
SaSA85_RS03485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA85_RS03490	COG1126	abc transporter atp-binding protein
SaSA85_RS03495	COG0745	RESPONSE REGULATOR receiver
SaSA85_RS03500	COG5002	protein histidine kinase activity
SaSA85_RS03505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA85_RS03510	COG2832	Protein of unknown function (DUF454)
SaSA85_RS03520	COG1196	nuclear chromosome segregation
SaSA85_RS03525	COG0561	phosphatase activity
SaSA85_RS03530	COG0561	phosphatase activity
SaSA85_RS03535	COG0552	protein localization to endoplasmic reticulum
SaSA85_RS03540	COG3689	TIGRFAM TIGR03943 family protein
SaSA85_RS03545	COG0701	Predicted permease
SaSA85_RS03560	COG2183	response to ionizing radiation
SaSA85_RS03565	COG3091	SprT-like family
SaSA85_RS03570	COG1983	PspC domain protein
SaSA85_RS03615	COG0826	peptidase U32
SaSA85_RS03620	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA85_RS03630	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA85_RS03645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA85_RS03645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SaSA85_RS03670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA85_RS03705	COG0772	Belongs to the SEDS family
SaSA85_RS03725	COG0768	penicillin binding
SaSA85_RS03740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA85_RS03770	COG2011	ABC-type metal ion transport system permease component
SaSA85_RS03775	COG1464	Belongs to the NlpA lipoprotein family
SaSA85_RS03780	COG0513	Belongs to the DEAD box helicase family
SaSA85_RS03790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA85_RS03795	COG0204	Acyl-transferase
SaSA85_RS03800	COG1555	photosystem II stabilization
SaSA85_RS03800	COG1596	polysaccharide export
SaSA85_RS03820	COG1609	Transcriptional regulator
SaSA85_RS03825	COG0657	acetylesterase activity
SaSA85_RS03830	COG2226	methyltransferase
SaSA85_RS03840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA85_RS03845	COG3711	transcriptional antiterminator
SaSA85_RS03870	COG1929	Belongs to the glycerate kinase type-1 family
SaSA85_RS03875	COG2610	gluconate transmembrane transporter activity
SaSA85_RS03890	COG1846	Transcriptional regulator
SaSA85_RS03895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA85_RS03910	COG0435	Glutathione S-transferase
SaSA85_RS03915	COG1187	pseudouridine synthase activity
SaSA85_RS03940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA85_RS03945	COG4122	O-methyltransferase activity
SaSA85_RS03955	COG4894	glucomannan catabolic process
SaSA85_RS03960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA85_RS03970	COG1442	glycosyl transferase family 8
SaSA85_RS03985	COG1476	TRANSCRIPTIONal
SaSA85_RS04000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA85_RS04010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA85_RS04025	COG1012	belongs to the aldehyde dehydrogenase family
SaSA85_RS04030	COG0726	polysaccharide deacetylase
SaSA85_RS04040	COG0513	Belongs to the DEAD box helicase family
SaSA85_RS04050	COG1956	GAF domain-containing protein
SaSA85_RS04055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA85_RS04070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA85_RS04100	COG4721	ABC-type cobalt transport system, permease component
SaSA85_RS04105	COG1122	ATPase activity
SaSA85_RS04115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA85_RS04125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA85_RS04130	COG0352	thiamine-phosphate diphosphorylase activity
SaSA85_RS04135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA85_RS04150	COG0024	Methionine aminopeptidase
SaSA85_RS04165	COG4708	membrane
SaSA85_RS04170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA85_RS04175	COG1597	lipid kinase activity
SaSA85_RS04180	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA85_RS04210	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA85_RS04235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SaSA85_RS04240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA85_RS04250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA85_RS04275	COG0072	phenylalanine-tRNA ligase activity
SaSA85_RS04275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA85_RS04280	COG2321	neutral zinc metallopeptidase
SaSA85_RS04300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA85_RS04305	COG0488	(ABC) transporter
SaSA85_RS04310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA85_RS04315	COG0022	dehydrogenase e1 component
SaSA85_RS04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA85_RS04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA85_RS04330	COG0095	Lipoate-protein ligase
SaSA85_RS04335	COG3442	glutamine amidotransferase
SaSA85_RS04340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA85_RS04345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA85_RS04370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA85_RS04390	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA85_RS04395	COG1518	maintenance of DNA repeat elements
SaSA85_RS04400	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA85_RS04420	COG0481	GTPase activity
SaSA85_RS04430	COG1418	mRNA catabolic process
SaSA85_RS04445	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SaSA85_RS04475	COG1131	(ABC) transporter
SaSA85_RS04480	COG1725	Transcriptional regulator
SaSA85_RS04490	COG0205	6-phosphofructokinase activity
SaSA85_RS04495	COG0469	pyruvate kinase activity
SaSA85_RS04500	COG0681	Belongs to the peptidase S26 family
SaSA85_RS04510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA85_RS04515	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA85_RS04520	COG0765	amino acid transport
SaSA85_RS04525	COG1126	abc transporter atp-binding protein
SaSA85_RS04545	COG1072	(Pantothenic acid kinase))
SaSA85_RS04550	COG2813	Specifically methylates the guanine in position
SaSA85_RS04555	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA85_RS04570	COG1079	Belongs to the binding-protein-dependent transport system permease family
SaSA85_RS04590	COG3764	Sortase (surface protein transpeptidase)
SaSA85_RS04595	COG0346	lactoylglutathione lyase activity
SaSA85_RS04615	COG2188	Transcriptional regulator
SaSA85_RS04620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA85_RS04630	COG1464	Belongs to the NlpA lipoprotein family
SaSA85_RS04645	COG1136	(ABC) transporter
SaSA85_RS04655	COG0745	RESPONSE REGULATOR receiver
SaSA85_RS04660	COG5002	protein histidine kinase activity
SaSA85_RS04665	COG4974	Belongs to the 'phage' integrase family
SaSA85_RS04685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA85_RS04695	COG5002	protein histidine kinase activity
SaSA85_RS04700	COG0745	RESPONSE REGULATOR receiver
SaSA85_RS04710	COG0704	Plays a role in the regulation of phosphate uptake
SaSA85_RS04715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA85_RS04720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA85_RS04725	COG0581	inorganic phosphate transmembrane transporter activity
SaSA85_RS04730	COG0573	inorganic phosphate transmembrane transporter activity
SaSA85_RS04750	COG4476	Belongs to the UPF0223 family
SaSA85_RS04760	COG0196	riboflavin kinase activity
SaSA85_RS04765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SaSA85_RS04795	COG1136	(ABC) transporter
SaSA85_RS04800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA85_RS04810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA85_RS04815	COG4604	ABC transporter, ATP-binding protein
SaSA85_RS04820	COG4605	iron ion homeostasis
SaSA85_RS04825	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA85_RS04830	COG0110	maltose O-acetyltransferase activity
SaSA85_RS04840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA85_RS04845	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA85_RS04850	COG1966	Carbon starvation protein
SaSA85_RS04855	COG3279	Response regulator of the LytR AlgR family
SaSA85_RS04860	COG3275	phosphorelay sensor kinase activity
SaSA85_RS04910	COG0505	Belongs to the CarA family
SaSA85_RS04925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA85_RS04940	COG0488	(ABC) transporter
SaSA85_RS04950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA85_RS04965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA85_RS05015	COG0095	Lipoate-protein ligase
SaSA85_RS05025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA85_RS05030	COG4684	Psort location CytoplasmicMembrane, score
SaSA85_RS05035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA85_RS05075	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA85_RS05090	COG1942	4-Oxalocrotonate Tautomerase
SaSA85_RS05110	COG0431	NADPH-dependent FMN reductase
SaSA85_RS05110	COG1053	succinate dehydrogenase
SaSA85_RS05110	COG3976	FMN-binding domain protein
SaSA85_RS05120	COG2233	PERMEase
SaSA85_RS05150	COG4221	oxidoreductase activity
SaSA85_RS05160	COG0564	pseudouridine synthase activity
SaSA85_RS05165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA85_RS05170	COG2357	RelA SpoT domain protein
SaSA85_RS05185	COG1104	cysteine desulfurase activity
SaSA85_RS05205	COG0628	permease
SaSA85_RS05220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SaSA85_RS05265	COG0561	phosphatase activity
SaSA85_RS05305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SaSA85_RS05310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SaSA85_RS05330	COG0285	dihydrofolate synthase activity
SaSA85_RS05335	COG2962	Rard protein
SaSA85_RS05355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA85_RS05365	COG1012	belongs to the aldehyde dehydrogenase family
SaSA85_RS05455	COG2261	transglycosylase associated protein
SaSA85_RS05480	COG1115	amino acid carrier protein
SaSA85_RS05485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA85_RS05495	COG1346	cytolysis
SaSA85_RS05510	COG0539	negative regulation of cytoplasmic translation
SaSA85_RS05530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA85_RS05540	COG0187	DNA topoisomerase II activity
SaSA85_RS05545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA85_RS05555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SaSA85_RS05565	COG2755	lipolytic protein G-D-S-L family
SaSA85_RS05565	COG1083	cytidylyl-transferase
SaSA85_RS05600	COG1216	Glycosyl transferase, family 2
SaSA85_RS05600	COG1442	glycosyl transferase family 8
SaSA85_RS05615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA85_RS05620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA85_RS05640	COG1316	TRANSCRIPTIONal
SaSA85_RS05680	COG3842	ATPase activity
SaSA85_RS05695	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SaSA85_RS05700	COG3527	Alpha-acetolactate decarboxylase
SaSA85_RS05705	COG0028	Belongs to the TPP enzyme family
SaSA85_RS05710	COG0457	Tetratricopeptide repeat
SaSA85_RS05715	COG0628	permease
SaSA85_RS05725	COG1051	belongs to the nudix hydrolase family
SaSA85_RS05730	COG5492	domain, Protein
SaSA85_RS05735	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA85_RS05745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA85_RS05750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA85_RS05760	COG2384	SAM-dependent methyltransferase
SaSA85_RS05790	COG0300	oxidoreductase activity
SaSA85_RS05805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SaSA85_RS05810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA85_RS05835	COG1573	uracil-dna glycosylase
SaSA85_RS05840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA85_RS05850	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA85_RS05865	COG0534	Mate efflux family protein
SaSA85_RS05920	COG2040	homocysteine
SaSA85_RS05925	COG0833	amino acid
SaSA85_RS05965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA85_RS05975	COG3425	synthase
SaSA85_RS05990	COG1272	protein, Hemolysin III
SaSA85_RS06035	COG0745	RESPONSE REGULATOR receiver
SaSA85_RS06055	COG1132	(ABC) transporter
SaSA85_RS06070	COG0488	(ABC) transporter
SaSA85_RS06100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA85_RS06100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA85_RS06100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA85_RS06105	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA85_RS06170	COG1837	Belongs to the UPF0109 family
SaSA85_RS06175	COG0228	four-way junction DNA binding
SaSA85_RS06185	COG1136	(ABC) transporter
SaSA85_RS06190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA85_RS06200	COG0505	Belongs to the CarA family
SaSA85_RS06210	COG0564	pseudouridine synthase activity
SaSA85_RS06220	COG0583	DNA-binding transcription factor activity
SaSA85_RS06225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA85_RS06245	COG0301	tRNA thio-modification
SaSA85_RS06250	COG1104	cysteine desulfurase activity
SaSA85_RS06290	COG1368	sulfuric ester hydrolase activity
SaSA85_RS06300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SaSA85_RS06310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SaSA85_RS06340	COG2244	polysaccharide biosynthetic process
SaSA85_RS06345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA85_RS06350	COG1120	ATPase activity
SaSA85_RS06355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SaSA85_RS06385	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA85_RS06390	COG1253	flavin adenine dinucleotide binding
SaSA85_RS06395	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA85_RS06400	COG1242	4 iron, 4 sulfur cluster binding
SaSA85_RS06405	COG0671	phosphoesterase, PA-phosphatase related
SaSA85_RS06410	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA85_RS06450	COG0297	glycogen (starch) synthase activity
SaSA85_RS06490	COG3475	LICD family
SaSA85_RS06505	COG0463	Glycosyl transferase, family 2
SaSA85_RS06510	COG1215	transferase activity, transferring glycosyl groups
SaSA85_RS06520	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA85_RS06525	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA85_RS06530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA85_RS06535	COG0358	DNA primase activity
SaSA85_RS06540	COG1970	mechanosensitive ion channel activity
SaSA85_RS06555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA85_RS06560	COG0004	ammonium transporteR
SaSA85_RS06570	COG1054	Belongs to the UPF0176 family
SaSA85_RS06590	COG0058	SHG alpha-glucan phosphorylase activity
SaSA85_RS06595	COG1640	4-alpha-glucanotransferase
SaSA85_RS06600	COG1609	Transcriptional regulator
SaSA85_RS06610	COG1175	transmembrane transport
SaSA85_RS06615	COG3833	ABC-type maltose transport systems, permease component
SaSA85_RS06650	COG0438	transferase activity, transferring glycosyl groups
SaSA85_RS06700	COG0765	amino acid transport
SaSA85_RS06705	COG1126	abc transporter atp-binding protein
SaSA85_RS06730	COG2309	aminopeptidase activity
SaSA85_RS06750	COG0656	L-ascorbic acid biosynthetic process
SaSA85_RS06755	COG0778	Nitroreductase
SaSA85_RS06760	COG0346	lactoylglutathione lyase activity
SaSA85_RS06770	COG1113	amino acid transport
SaSA85_RS06780	COG0557	exoribonuclease II activity
SaSA85_RS06805	COG1131	(ABC) transporter
SaSA85_RS06815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SaSA85_RS06880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SaSA85_RS06910	COG1702	phosphate starvation-inducible protein PhoH
SaSA85_RS06935	COG0233	cytoplasmic translational termination
SaSA85_RS06950	COG0444	Belongs to the ABC transporter superfamily
SaSA85_RS06955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA85_RS06960	COG0601	transmembrane transport
SaSA85_RS06965	COG0747	negative chemotaxis
SaSA85_RS06970	COG0081	regulation of translation
SaSA85_RS06975	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA85_RS06985	COG1473	amidohydrolase
SaSA85_RS06990	COG0583	DNA-binding transcription factor activity
SaSA85_RS07005	COG1674	ftsk spoiiie
SaSA85_RS07010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA85_RS07035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA85_RS07070	COG0673	inositol 2-dehydrogenase activity
SaSA85_RS07085	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA85_RS07135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA85_RS07135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA85_RS07155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA85_RS07165	COG0708	Exodeoxyribonuclease III
SaSA85_RS07170	COG1393	Belongs to the ArsC family
SaSA85_RS07175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA85_RS07180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA85_RS07190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA85_RS07215	COG0470	DNA polymerase III
SaSA85_RS07225	COG0517	IMP dehydrogenase activity
SaSA85_RS07245	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA85_RS07265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SaSA85_RS07270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA85_RS07280	COG0531	amino acid
SaSA85_RS07285	COG0569	domain protein
SaSA85_RS07305	COG1187	pseudouridine synthase activity
SaSA85_RS07340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA85_RS07355	COG1827	regulation of RNA biosynthetic process
SaSA85_RS07370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA85_RS07375	COG1254	Belongs to the acylphosphatase family
SaSA85_RS07385	COG0765	amino acid transport
SaSA85_RS07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA85_RS07405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA85_RS07430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA85_RS07440	COG1484	DNA-dependent DNA replication
SaSA85_RS07455	COG5002	protein histidine kinase activity
SaSA85_RS07470	COG0501	Belongs to the peptidase M48B family
SaSA85_RS07475	COG1704	LemA family
SaSA85_RS07480	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA85_RS07485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA85_RS07490	COG0569	domain protein
SaSA85_RS07515	COG1114	Component of the transport system for branched-chain amino acids
SaSA85_RS07520	COG1063	alcohol dehydrogenase
SaSA85_RS07545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA85_RS07550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA85_RS07560	COG0217	transcriptional regulatory protein
SaSA85_RS07570	COG2376	Dihydroxyacetone kinase
SaSA85_RS07575	COG1309	transcriptional regulator
SaSA85_RS07585	COG2376	Dihydroxyacetone kinase
SaSA85_RS07590	COG1461	Dihydroxyacetone kinase
SaSA85_RS07595	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA85_RS07600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA85_RS07610	COG0789	Transcriptional regulator
SaSA85_RS07615	COG1323	Belongs to the UPF0348 family
SaSA85_RS07625	COG2226	methyltransferase
SaSA85_RS07630	COG0799	negative regulation of ribosome biogenesis
SaSA85_RS07640	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA85_RS07645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA85_RS07650	COG1534	Rna-binding protein
SaSA85_RS07655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA85_RS07675	COG0154	amidase activity
SaSA85_RS07680	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA85_RS07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA85_RS07685	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA85_RS07695	COG0517	IMP dehydrogenase activity
SaSA85_RS07700	COG1024	Enoyl-CoA hydratase
SaSA85_RS07700	COG1250	3-hydroxyacyl-CoA dehydrogenase
SaSA85_RS07710	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA85_RS07715	COG0436	Aminotransferase
SaSA85_RS07720	COG0589	response to stress
SaSA85_RS07730	COG0252	asparaginase activity
SaSA85_RS07740	COG4989	oxidoreductase activity
SaSA85_RS07745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA85_RS07750	COG3942	CHAP domain
SaSA85_RS07750	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA85_RS07760	COG0736	holo-[acyl-carrier-protein] synthase activity
SaSA85_RS07780	COG1940	carbohydrate kinase activity
SaSA85_RS07785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA85_RS07785	COG2190	(PTS) system
SaSA85_RS07785	COG1263	PTS System
SaSA85_RS07790	COG1621	beta-fructofuranosidase activity
SaSA85_RS07795	COG1609	Transcriptional regulator
SaSA85_RS07800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA85_RS07810	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SaSA85_RS07845	COG2131	deaminase
SaSA85_RS07850	COG0006	proline dipeptidase activity
SaSA85_RS07860	COG2814	Major facilitator Superfamily
SaSA85_RS07890	COG0360	Binds together with S18 to 16S ribosomal RNA
SaSA85_RS07895	COG1194	a g-specific adenine glycosylase
SaSA85_RS07930	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA85_RS07935	COG0681	Belongs to the peptidase S26 family
SaSA85_RS07940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA85_RS07955	COG1882	Formate acetyltransferase
SaSA85_RS07965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA85_RS07980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA85_RS07990	COG2814	Major facilitator Superfamily
SaSA85_RS07995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA85_RS08015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA85_RS08020	COG4988	ABC transporter
SaSA85_RS08025	COG1294	oxidase, subunit
SaSA85_RS08035	COG1252	NADH dehydrogenase
SaSA85_RS08060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA85_RS08080	COG2081	HI0933 family
SaSA85_RS08115	COG1214	PFAM Peptidase M22, glycoprotease
SaSA85_RS08130	COG3942	CHAP domain
SaSA85_RS08135	COG0174	glutamine synthetase
SaSA85_RS08140	COG0789	Transcriptional regulator
SaSA85_RS08155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA85_RS08185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA85_RS08230	COG0693	protein deglycase activity
SaSA85_RS08265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA85_RS08270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA85_RS08275	COG1696	Membrane protein involved in D-alanine export
SaSA85_RS08305	COG3314	Sporulation integral membrane protein YlbJ
SaSA85_RS08315	COG3448	diguanylate cyclase activity
SaSA85_RS08315	COG4175	Glycine betaine
SaSA85_RS08325	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SaSA85_RS08355	COG3775	system Galactitol-specific IIC component
SaSA85_RS08370	COG1609	Transcriptional regulator
SaSA85_RS08420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA85_RS08455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA85_RS08460	COG1428	Deoxynucleoside kinase
SaSA85_RS08470	COG0542	response to heat
SaSA85_RS08475	COG4463	regulation of RNA biosynthetic process
SaSA85_RS08485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SaSA85_RS08510	COG0025	NhaP-type Na H and K H
SaSA85_RS08520	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA85_RS08525	COG3590	peptidase
SaSA85_RS08555	COG1609	Transcriptional regulator
SaSA85_RS08565	COG3716	PTS system mannose fructose sorbose family IID component
SaSA85_RS08575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA85_RS08580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA85_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA85_RS08635	COG2176	DNA-directed DNA polymerase activity
SaSA85_RS08655	COG4589	Belongs to the CDS family
SaSA85_RS08665	COG1862	Preprotein translocase
SaSA85_RS08685	COG3290	protein histidine kinase activity
SaSA85_RS08695	COG4565	transcriptional regulatory protein
SaSA85_RS08700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA85_RS08710	COG3842	ATPase activity
SaSA85_RS08785	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA85_RS08805	COG1363	Peptidase, m42
SaSA85_RS08825	COG2972	Histidine kinase
SaSA85_RS08830	COG3716	PTS system mannose fructose sorbose family IID component
SaSA85_RS08835	COG3715	PTS system
SaSA85_RS08865	COG1131	(ABC) transporter
SaSA85_RS08885	COG3290	protein histidine kinase activity
SaSA85_RS08905	COG2190	(PTS) system
SaSA85_RS08905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA85_RS08905	COG1263	PTS System
SaSA85_RS08925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA85_RS08930	COG0581	inorganic phosphate transmembrane transporter activity
SaSA85_RS08950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA85_RS08965	COG0789	Transcriptional regulator
SaSA85_RS09000	COG0456	acetyltransferase
SaSA85_RS09005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA85_RS09080	COG1131	(ABC) transporter
SaSA85_RS09090	COG1396	sequence-specific DNA binding
SaSA85_RS09110	COG2897	thiosulfate sulfurtransferase activity
SaSA85_RS09130	COG0371	Dehydrogenase
SaSA85_RS09155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA85_RS09185	COG0495	leucyl-tRNA aminoacylation
SaSA85_RS09195	COG2814	Major facilitator Superfamily
SaSA85_RS09200	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA85_RS09230	COG0564	pseudouridine synthase activity
SaSA85_RS09250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA85_RS09255	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA85_RS09275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA85_RS09280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA85_RS09280	COG1116	anion transmembrane transporter activity
SaSA85_RS09290	COG0561	phosphatase activity
SaSA85_RS09295	COG2514	catechol 2,3-dioxygenase activity
SaSA85_RS09305	COG0602	queuosine metabolic process
SaSA85_RS09325	COG1328	CTP reductase activity
SaSA85_RS09345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SaSA85_RS09355	COG1393	Belongs to the ArsC family
SaSA85_RS09360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA85_RS09365	COG1058	Belongs to the CinA family
SaSA85_RS09365	COG1546	Belongs to the CinA family
SaSA85_RS09410	COG0018	arginyl-trna synthetase
SaSA85_RS09420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA85_RS09435	COG0124	histidyl-tRNA synthetase
SaSA85_RS09445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SaSA85_RS09480	COG1174	glycine betaine transport
SaSA85_RS09490	COG0392	lysyltransferase activity
SaSA85_RS09490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA85_RS09530	COG0305	Participates in initiation and elongation during chromosome replication
SaSA85_RS09555	COG0482	sulfurtransferase activity
SaSA85_RS09560	COG1760	l-serine dehydratase
SaSA85_RS09565	COG1760	l-serine dehydratase
SaSA85_RS09570	COG0741	lytic transglycosylase activity
SaSA85_RS09595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA85_RS09600	COG0612	Peptidase, M16
SaSA85_RS09605	COG0612	Peptidase, M16
SaSA85_RS09610	COG2501	S4 domain
SaSA85_RS09630	COG0517	IMP dehydrogenase activity
SaSA85_RS09630	COG0516	GMP reductase activity
SaSA85_RS09655	COG0454	-acetyltransferase
SaSA85_RS09660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA85_RS09670	COG0549	Belongs to the carbamate kinase family
SaSA85_RS09690	COG0488	(ABC) transporter
SaSA85_RS09695	COG4485	Bacterial membrane protein, YfhO
SaSA85_RS09715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SaSA85_RS09720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA85_RS09725	COG1475	DNA binding