locus-tag	class	description
BB268_RS00175	COG0436	Aminotransferase
BB268_RS00195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB268_RS00205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB268_RS00220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BB268_RS00255	COG1175	transmembrane transport
BB268_RS00260	COG0395	ABC-type sugar transport system, permease component
BB268_RS00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB268_RS00285	COG3458	cephalosporin-C deacetylase activity
BB268_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB268_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB268_RS00330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB268_RS00340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BB268_RS00340	COG2755	lipolytic protein G-D-S-L family
BB268_RS00345	COG1454	alcohol dehydrogenase
BB268_RS00345	COG1012	belongs to the aldehyde dehydrogenase family
BB268_RS00350	COG1064	alcohol dehydrogenase
BB268_RS00360	COG0534	Mate efflux family protein
BB268_RS00470	COG0201	protein transport
BB268_RS00490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BB268_RS00500	COG0202	RNA polymerase activity
BB268_RS00660	COG3561	AntA/AntB antirepressor
BB268_RS00690	COG0556	nucleotide-excision repair
BB268_RS00780	COG1783	phage Terminase large subunit
BB268_RS00915	COG1705	Flagellar rod assembly protein muramidase FlgJ
BB268_RS00930	COG0443	Heat shock 70 kDa protein
BB268_RS00940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB268_RS00950	COG0351	phosphomethylpyrimidine kinase
BB268_RS00955	COG4720	Psort location CytoplasmicMembrane, score
BB268_RS00965	COG0668	transmembrane transport
BB268_RS00995	COG0756	dUTP diphosphatase activity
BB268_RS01010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB268_RS01025	COG1879	ABC-type sugar transport system periplasmic component
BB268_RS01030	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB268_RS01045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB268_RS01050	COG1609	Transcriptional regulator
BB268_RS01060	COG0577	efflux transmembrane transporter activity
BB268_RS01065	COG1136	(ABC) transporter
BB268_RS01070	COG0745	RESPONSE REGULATOR receiver
BB268_RS01075	COG5002	protein histidine kinase activity
BB268_RS01090	COG0191	fructose-bisphosphate aldolase activity
BB268_RS01110	COG1461	Dihydroxyacetone kinase
BB268_RS01145	COG1126	abc transporter atp-binding protein
BB268_RS01150	COG0765	amino acid transport
BB268_RS01170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB268_RS01180	COG0719	Fe-S assembly protein
BB268_RS01185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB268_RS01195	COG0719	Fe-S assembly protein
BB268_RS01200	COG1686	Belongs to the peptidase S11 family
BB268_RS01205	COG1686	Belongs to the peptidase S11 family
BB268_RS01210	COG4166	transmembrane transport
BB268_RS01215	COG0601	transmembrane transport
BB268_RS01220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB268_RS01225	COG0444	Belongs to the ABC transporter superfamily
BB268_RS01230	COG4608	Belongs to the ABC transporter superfamily
BB268_RS01270	COG1121	(ABC) transporter
BB268_RS01275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB268_RS01290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB268_RS01290	COG4499	WXG100 protein secretion system (Wss), protein YukC
BB268_RS01315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BB268_RS01320	COG1459	type II secretion system
BB268_RS01380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BB268_RS01385	COG1363	Peptidase, m42
BB268_RS01400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB268_RS01405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB268_RS01420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB268_RS01440	COG1346	cytolysis
BB268_RS01455	COG0601	transmembrane transport
BB268_RS01460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB268_RS01465	COG1122	ATPase activity
BB268_RS01475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB268_RS01475	COG1263	PTS System
BB268_RS01480	COG0366	Alpha amylase catalytic
BB268_RS01485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB268_RS01500	COG3959	Transketolase, thiamine diphosphate binding domain
BB268_RS01505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB268_RS01510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB268_RS01530	COG1045	serine acetyltransferase
BB268_RS01545	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BB268_RS01580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BB268_RS01590	COG4974	Belongs to the 'phage' integrase family
BB268_RS01700	COG1396	sequence-specific DNA binding
BB268_RS01705	COG2814	Major facilitator Superfamily
BB268_RS01715	COG1732	Glycine betaine
BB268_RS01855	COG0519	Catalyzes the synthesis of GMP from XMP
BB268_RS01900	COG1695	Transcriptional regulator
BB268_RS01915	COG1755	Isoprenylcysteine carboxyl methyltransferase
BB268_RS01955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB268_RS01960	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB268_RS01980	COG1131	(ABC) transporter
BB268_RS01990	COG2190	(PTS) system
BB268_RS01990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB268_RS01990	COG1263	PTS System
BB268_RS01995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BB268_RS02015	COG0768	penicillin binding
BB268_RS02025	COG0513	Belongs to the DEAD box helicase family
BB268_RS02040	COG1126	abc transporter atp-binding protein
BB268_RS02050	COG0492	ferredoxin-NADP+ reductase activity
BB268_RS02055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BB268_RS02065	COG3579	cysteine-type endopeptidase activity
BB268_RS02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB268_RS02100	COG0116	Belongs to the methyltransferase superfamily
BB268_RS02110	COG1854	S-ribosylhomocysteine lyase activity
BB268_RS02115	COG4372	Transposase
BB268_RS02115	COG1418	mRNA catabolic process
BB268_RS02125	COG1131	(ABC) transporter
BB268_RS02135	COG4585	Histidine kinase
BB268_RS02140	COG2197	response regulator
BB268_RS02150	COG0194	GDP metabolic process
BB268_RS02160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB268_RS02165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB268_RS02170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB268_RS02170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB268_RS02180	COG2815	serine threonine protein kinase
BB268_RS02180	COG0515	serine threonine protein kinase
BB268_RS02190	COG4585	Histidine kinase
BB268_RS02195	COG2197	response regulator
BB268_RS02205	COG1098	S1 RNA binding domain
BB268_RS02210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BB268_RS02215	COG1349	DNA-binding transcription factor activity
BB268_RS02225	COG1447	Phosphotransferase system cellobiose-specific component IIA
BB268_RS02235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB268_RS02240	COG1882	Formate acetyltransferase
BB268_RS02260	COG1739	Uncharacterized protein family UPF0029
BB268_RS02265	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BB268_RS02270	COG1040	competence protein
BB268_RS02305	COG0527	aspartate kinase activity
BB268_RS02310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB268_RS02315	COG1024	Enoyl-CoA hydratase
BB268_RS02325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB268_RS02335	COG2070	2-Nitropropane dioxygenase
BB268_RS02340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BB268_RS02345	COG1028	Short-chain dehydrogenase reductase Sdr
BB268_RS02350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB268_RS02365	COG0439	Biotin carboxylase
BB268_RS02385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BB268_RS02400	COG3716	PTS system mannose fructose sorbose family IID component
BB268_RS02405	COG3715	PTS system
BB268_RS02420	COG0561	phosphatase activity
BB268_RS02435	COG2252	PERMEase
BB268_RS02440	COG0802	atpase or kinase
BB268_RS02450	COG1316	TRANSCRIPTIONal
BB268_RS02460	COG0537	adenosine 5'-monophosphoramidase activity
BB268_RS02475	COG1131	(ABC) transporter
BB268_RS02480	COG4473	ABC transporter
BB268_RS02490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BB268_RS02505	COG0195	Participates in both transcription termination and antitermination
BB268_RS02510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BB268_RS02520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BB268_RS02525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BB268_RS02550	COG2860	membrane
BB268_RS02560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB268_RS02560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB268_RS02565	COG1832	CoA-binding protein
BB268_RS02585	COG5002	protein histidine kinase activity
BB268_RS02605	COG1268	BioY protein
BB268_RS02610	COG1234	tRNA 3'-trailer cleavage
BB268_RS02625	COG0166	Belongs to the GPI family
BB268_RS02630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BB268_RS02635	COG0457	Tetratricopeptide repeat
BB268_RS02635	COG0705	Rhomboid family
BB268_RS02640	COG1744	ABC transporter substrate-binding protein PnrA-like
BB268_RS02645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BB268_RS02660	COG0706	membrane insertase activity
BB268_RS02720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB268_RS02730	COG2153	protein acetylation
BB268_RS02740	COG1442	glycosyl transferase family 8
BB268_RS02740	COG1216	Glycosyl transferase, family 2
BB268_RS02785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB268_RS02795	COG0789	Transcriptional regulator
BB268_RS02805	COG0656	L-ascorbic acid biosynthetic process
BB268_RS02850	COG2226	methyltransferase
BB268_RS02860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB268_RS02865	COG3414	Phosphotransferase system galactitol-specific IIB component
BB268_RS02870	COG3775	system Galactitol-specific IIC component
BB268_RS02875	COG0235	Class ii aldolase
BB268_RS02885	COG3775	system Galactitol-specific IIC component
BB268_RS02890	COG3414	Phosphotransferase system galactitol-specific IIB component
BB268_RS02895	COG2207	Transcriptional regulator
BB268_RS02910	COG1175	transmembrane transport
BB268_RS02925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BB268_RS02935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB268_RS02940	COG2017	converts alpha-aldose to the beta-anomer
BB268_RS03005	COG1518	maintenance of DNA repeat elements
BB268_RS03010	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BB268_RS03015	COG0673	inositol 2-dehydrogenase activity
BB268_RS03025	COG2315	Protein conserved in bacteria
BB268_RS03040	COG0742	ribosomal rna small subunit methyltransferase
BB268_RS03055	COG3480	Lon protease (S16) C-terminal proteolytic domain
BB268_RS03060	COG0737	Belongs to the 5'-nucleotidase family
BB268_RS03065	COG4470	Protein conserved in bacteria
BB268_RS03080	COG1132	(ABC) transporter
BB268_RS03085	COG1132	(ABC) transporter
BB268_RS03090	COG0512	Glutamine amidotransferase of anthranilate synthase
BB268_RS03095	COG1268	BioY protein
BB268_RS03100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BB268_RS03120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BB268_RS03135	COG1940	carbohydrate kinase activity
BB268_RS03140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB268_RS03145	COG1217	gtp-binding protein TYPA
BB268_RS03155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BB268_RS03180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB268_RS03190	COG0762	integral membrane protein
BB268_RS03195	COG2302	S4 RNA-binding domain
BB268_RS03200	COG3599	regulation of cell shape
BB268_RS03215	COG0494	nUDIX hydrolase
BB268_RS03220	COG0542	response to heat
BB268_RS03225	COG4703	Protein of unknown function (DUF1797)
BB268_RS03230	COG0765	amino acid transport
BB268_RS03235	COG1126	abc transporter atp-binding protein
BB268_RS03240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB268_RS03250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BB268_RS03255	COG1570	exodeoxyribonuclease VII activity
BB268_RS03260	COG1722	exodeoxyribonuclease VII activity
BB268_RS03270	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BB268_RS03275	COG1438	arginine binding
BB268_RS03280	COG0497	DNA recombination
BB268_RS03285	COG1307	EDD domain protein, DegV family
BB268_RS03290	COG2755	lipolytic protein G-D-S-L family
BB268_RS03335	COG1078	dGTPase activity
BB268_RS03360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BB268_RS03370	COG2884	Cell division ATP-binding protein ftsE
BB268_RS03375	COG2177	Part of the ABC transporter FtsEX involved in
BB268_RS03395	COG1199	ATP-dependent helicase activity
BB268_RS03395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB268_RS03400	COG0436	Aminotransferase
BB268_RS03405	COG0017	Asparaginyl-tRNA synthetase
BB268_RS03425	COG1660	Displays ATPase and GTPase activities
BB268_RS03450	COG0254	rRNA binding
BB268_RS03455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BB268_RS03460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB268_RS03465	COG0716	FMN binding
BB268_RS03470	COG1605	Chorismate mutase
BB268_RS03470	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BB268_RS03475	COG0038	chloride channel
BB268_RS03480	COG0335	large ribosomal subunit rRNA binding
BB268_RS03520	COG1136	(ABC) transporter
BB268_RS03535	COG5002	protein histidine kinase activity
BB268_RS03555	COG0772	Belongs to the SEDS family
BB268_RS03575	COG0560	Phosphoserine phosphatase
BB268_RS03590	COG0148	phosphopyruvate hydratase activity
BB268_RS03625	COG3700	Belongs to the class B bacterial acid phosphatase family
BB268_RS03725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB268_RS03730	COG4555	ABC transporter
BB268_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
BB268_RS03760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB268_RS03765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BB268_RS03785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BB268_RS03790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB268_RS03810	COG3064	Membrane
BB268_RS03810	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BB268_RS03825	COG3590	peptidase
BB268_RS03830	COG3590	peptidase
BB268_RS03880	COG1136	(ABC) transporter
BB268_RS03895	COG0586	Pfam SNARE associated Golgi protein
BB268_RS03900	COG4619	ABC transporter
BB268_RS03905	COG0390	transport system, permease component
BB268_RS03915	COG0583	DNA-binding transcription factor activity
BB268_RS03930	COG2211	Major facilitator Superfamily
BB268_RS03940	COG3250	beta-galactosidase activity
BB268_RS03945	COG2186	Transcriptional regulator
BB268_RS03950	COG0800	Aldolase
BB268_RS03965	COG1028	Short-chain dehydrogenase reductase Sdr
BB268_RS03985	COG1609	Transcriptional regulator
BB268_RS04000	COG0438	transferase activity, transferring glycosyl groups
BB268_RS04025	COG0765	amino acid transport
BB268_RS04030	COG0765	amino acid transport
BB268_RS04035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB268_RS04040	COG1126	abc transporter atp-binding protein
BB268_RS04045	COG0745	RESPONSE REGULATOR receiver
BB268_RS04050	COG5002	protein histidine kinase activity
BB268_RS04055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BB268_RS04060	COG2832	Protein of unknown function (DUF454)
BB268_RS04070	COG1196	nuclear chromosome segregation
BB268_RS04075	COG0561	phosphatase activity
BB268_RS04080	COG0561	phosphatase activity
BB268_RS04085	COG0552	protein localization to endoplasmic reticulum
BB268_RS04090	COG3689	TIGRFAM TIGR03943 family protein
BB268_RS04095	COG0701	Predicted permease
BB268_RS04110	COG2183	response to ionizing radiation
BB268_RS04115	COG3091	SprT-like family
BB268_RS04120	COG1983	PspC domain protein
BB268_RS04160	COG0826	peptidase U32
BB268_RS04165	COG4443	Transcriptional Coactivator p15 (PC4)
BB268_RS04175	COG1914	H( )-stimulated, divalent metal cation uptake system
BB268_RS04190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB268_RS04190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB268_RS04215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB268_RS04240	COG1164	Oligoendopeptidase f
BB268_RS04250	COG0772	Belongs to the SEDS family
BB268_RS04270	COG0768	penicillin binding
BB268_RS04285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB268_RS04290	COG2223	nitrite transmembrane transporter activity
BB268_RS04320	COG2011	ABC-type metal ion transport system permease component
BB268_RS04325	COG1464	Belongs to the NlpA lipoprotein family
BB268_RS04330	COG0513	Belongs to the DEAD box helicase family
BB268_RS04340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BB268_RS04345	COG0204	Acyl-transferase
BB268_RS04350	COG1596	polysaccharide export
BB268_RS04350	COG1555	photosystem II stabilization
BB268_RS04355	COG2333	competence protein COMEC
BB268_RS04355	COG0658	competence protein
BB268_RS04360	COG0561	phosphatase activity
BB268_RS04365	COG1609	Transcriptional regulator
BB268_RS04370	COG0657	acetylesterase activity
BB268_RS04375	COG2226	methyltransferase
BB268_RS04385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB268_RS04390	COG3711	transcriptional antiterminator
BB268_RS04395	COG2190	(PTS) system
BB268_RS04395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB268_RS04395	COG1263	PTS System
BB268_RS04405	COG3835	regulator
BB268_RS04410	COG1929	Belongs to the glycerate kinase type-1 family
BB268_RS04415	COG2610	gluconate transmembrane transporter activity
BB268_RS04425	COG1846	Transcriptional regulator
BB268_RS04440	COG0363	glucosamine-6-phosphate deaminase activity
BB268_RS04445	COG0435	Glutathione S-transferase
BB268_RS04450	COG1187	pseudouridine synthase activity
BB268_RS04475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BB268_RS04480	COG4122	O-methyltransferase activity
BB268_RS04490	COG4894	glucomannan catabolic process
BB268_RS04505	COG1442	glycosyl transferase family 8
BB268_RS04520	COG1476	TRANSCRIPTIONal
BB268_RS04535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB268_RS04540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB268_RS04545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB268_RS04560	COG1012	belongs to the aldehyde dehydrogenase family
BB268_RS04565	COG0726	polysaccharide deacetylase
BB268_RS04580	COG1956	GAF domain-containing protein
BB268_RS04585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB268_RS04595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BB268_RS04595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BB268_RS04625	COG4721	ABC-type cobalt transport system, permease component
BB268_RS04630	COG1122	ATPase activity
BB268_RS04640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BB268_RS04670	COG4109	DRTGG domain
BB268_RS04675	COG0024	Methionine aminopeptidase
BB268_RS04685	COG2246	polysaccharide biosynthetic process
BB268_RS04690	COG4708	membrane
BB268_RS04700	COG1597	lipid kinase activity
BB268_RS04705	COG1523	belongs to the glycosyl hydrolase 13 family
BB268_RS04720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BB268_RS04800	COG0072	phenylalanine-tRNA ligase activity
BB268_RS04800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB268_RS04805	COG2321	neutral zinc metallopeptidase
BB268_RS04830	COG0488	(ABC) transporter
BB268_RS04835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BB268_RS04840	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB268_RS04840	COG0022	dehydrogenase e1 component
BB268_RS04845	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB268_RS04855	COG0095	Lipoate-protein ligase
BB268_RS04860	COG3442	glutamine amidotransferase
BB268_RS04865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB268_RS04870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BB268_RS04895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB268_RS04905	COG0647	UMP catabolic process
BB268_RS04915	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BB268_RS04920	COG1518	maintenance of DNA repeat elements
BB268_RS04925	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BB268_RS04945	COG0481	GTPase activity
BB268_RS04955	COG1418	mRNA catabolic process
BB268_RS04960	COG0456	acetyltransferase
BB268_RS04970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB268_RS05000	COG1131	(ABC) transporter
BB268_RS05005	COG1725	Transcriptional regulator
BB268_RS05015	COG0205	6-phosphofructokinase activity
BB268_RS05020	COG0469	pyruvate kinase activity
BB268_RS05035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB268_RS05040	COG2824	Alkylphosphonate utilization operon protein PhnA
BB268_RS05045	COG0765	amino acid transport
BB268_RS05050	COG1126	abc transporter atp-binding protein
BB268_RS05065	COG1072	(Pantothenic acid kinase))
BB268_RS05070	COG2813	Specifically methylates the guanine in position
BB268_RS05080	COG1744	ABC transporter substrate-binding protein PnrA-like
BB268_RS05085	COG3845	ABC transporter
BB268_RS05090	COG4603	Belongs to the binding-protein-dependent transport system permease family
BB268_RS05095	COG1079	Belongs to the binding-protein-dependent transport system permease family
BB268_RS05115	COG3764	Sortase (surface protein transpeptidase)
BB268_RS05120	COG0346	lactoylglutathione lyase activity
BB268_RS05145	COG2188	Transcriptional regulator
BB268_RS05160	COG1464	Belongs to the NlpA lipoprotein family
BB268_RS05175	COG1136	(ABC) transporter
BB268_RS05185	COG0745	RESPONSE REGULATOR receiver
BB268_RS05190	COG5002	protein histidine kinase activity
BB268_RS05195	COG4974	Belongs to the 'phage' integrase family
BB268_RS05200	COG4166	transmembrane transport
BB268_RS05215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BB268_RS05220	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BB268_RS05225	COG5002	protein histidine kinase activity
BB268_RS05230	COG0745	RESPONSE REGULATOR receiver
BB268_RS05240	COG0704	Plays a role in the regulation of phosphate uptake
BB268_RS05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BB268_RS05250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BB268_RS05255	COG0581	inorganic phosphate transmembrane transporter activity
BB268_RS05260	COG0573	inorganic phosphate transmembrane transporter activity
BB268_RS05270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB268_RS05270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BB268_RS05275	COG0483	inositol monophosphate 1-phosphatase activity
BB268_RS05290	COG0196	riboflavin kinase activity
BB268_RS05295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BB268_RS05325	COG1136	(ABC) transporter
BB268_RS05330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB268_RS05335	COG0758	DNA mediated transformation
BB268_RS05340	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BB268_RS05345	COG4604	ABC transporter, ATP-binding protein
BB268_RS05350	COG4605	iron ion homeostasis
BB268_RS05355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB268_RS05360	COG0110	maltose O-acetyltransferase activity
BB268_RS05370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BB268_RS05375	COG1376	ErfK ybiS ycfS ynhG family protein
BB268_RS05380	COG1966	Carbon starvation protein
BB268_RS05385	COG3279	Response regulator of the LytR AlgR family
BB268_RS05390	COG3275	phosphorelay sensor kinase activity
BB268_RS05500	COG0505	Belongs to the CarA family
BB268_RS05510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB268_RS05530	COG0488	(ABC) transporter
BB268_RS05550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB268_RS05600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BB268_RS05605	COG4684	Psort location CytoplasmicMembrane, score
BB268_RS05610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB268_RS05620	COG1132	(ABC) transporter
BB268_RS05650	COG2890	protein-(glutamine-N5) methyltransferase activity
BB268_RS05665	COG1942	4-Oxalocrotonate Tautomerase
BB268_RS05680	COG1053	succinate dehydrogenase
BB268_RS05680	COG3976	FMN-binding domain protein
BB268_RS05680	COG0431	NADPH-dependent FMN reductase
BB268_RS05690	COG2233	PERMEase
BB268_RS05705	COG0477	Major facilitator Superfamily
BB268_RS05720	COG4221	oxidoreductase activity
BB268_RS05725	COG0280	phosphate acetyltransferase
BB268_RS05730	COG0564	pseudouridine synthase activity
BB268_RS05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BB268_RS05740	COG2357	RelA SpoT domain protein
BB268_RS05755	COG1104	cysteine desulfurase activity
BB268_RS05765	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BB268_RS05770	COG2003	Belongs to the UPF0758 family
BB268_RS05775	COG0628	permease
BB268_RS05780	COG2723	6-phospho-beta-galactosidase activity
BB268_RS05790	COG0561	phosphatase activity
BB268_RS05805	COG0038	chloride channel
BB268_RS05815	COG1177	transmembrane transport
BB268_RS05820	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB268_RS05830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB268_RS05835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BB268_RS05855	COG0285	dihydrofolate synthase activity
BB268_RS05860	COG2962	Rard protein
BB268_RS05875	COG0726	polysaccharide deacetylase
BB268_RS05880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB268_RS05895	COG1012	belongs to the aldehyde dehydrogenase family
BB268_RS05970	COG2261	transglycosylase associated protein
BB268_RS05995	COG1115	amino acid carrier protein
BB268_RS06000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BB268_RS06010	COG1346	cytolysis
BB268_RS06025	COG0539	negative regulation of cytoplasmic translation
BB268_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB268_RS06055	COG0187	DNA topoisomerase II activity
BB268_RS06060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BB268_RS06070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB268_RS06080	COG2755	lipolytic protein G-D-S-L family
BB268_RS06080	COG1083	cytidylyl-transferase
BB268_RS06095	COG2089	acid synthase
BB268_RS06110	COG1442	glycosyl transferase family 8
BB268_RS06110	COG1216	Glycosyl transferase, family 2
BB268_RS06115	COG1442	glycosyl transferase family 8
BB268_RS06115	COG1216	Glycosyl transferase, family 2
BB268_RS06130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB268_RS06155	COG1316	TRANSCRIPTIONal
BB268_RS06180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BB268_RS06195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BB268_RS06215	COG3842	ATPase activity
BB268_RS06230	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BB268_RS06235	COG3527	Alpha-acetolactate decarboxylase
BB268_RS06240	COG0028	Belongs to the TPP enzyme family
BB268_RS06245	COG0457	Tetratricopeptide repeat
BB268_RS06250	COG0628	permease
BB268_RS06260	COG1051	belongs to the nudix hydrolase family
BB268_RS06505	COG3561	AntA/AntB antirepressor
BB268_RS06515	COG2932	Transcriptional regulator
BB268_RS06525	COG2314	TM2 domain
BB268_RS06535	COG5492	domain, Protein
BB268_RS06540	COG1088	dTDP-glucose 4,6-dehydratase activity
BB268_RS06550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BB268_RS06555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB268_RS06565	COG2384	SAM-dependent methyltransferase
BB268_RS06590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BB268_RS06590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BB268_RS06595	COG0300	oxidoreductase activity
BB268_RS06640	COG1573	uracil-dna glycosylase
BB268_RS06645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB268_RS06655	COG0584	glycerophosphoryl diester phosphodiesterase
BB268_RS06660	COG0322	excinuclease ABC activity
BB268_RS06670	COG0534	Mate efflux family protein
BB268_RS06710	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB268_RS06730	COG2176	DNA-directed DNA polymerase activity
BB268_RS06740	COG4974	Belongs to the 'phage' integrase family
BB268_RS06770	COG1674	ftsk spoiiie
BB268_RS06810	COG2040	homocysteine
BB268_RS06815	COG0833	amino acid
BB268_RS06855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BB268_RS06865	COG3425	synthase
BB268_RS06880	COG1272	protein, Hemolysin III
BB268_RS06925	COG0745	RESPONSE REGULATOR receiver
BB268_RS06930	COG2357	RelA SpoT domain protein
BB268_RS06935	COG1132	(ABC) transporter
BB268_RS06950	COG0737	Belongs to the 5'-nucleotidase family
BB268_RS06955	COG0242	peptide deformylase activity
BB268_RS06960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB268_RS06970	COG1132	(ABC) transporter
BB268_RS06985	COG0488	(ABC) transporter
BB268_RS07015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB268_RS07015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB268_RS07015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB268_RS07020	COG1105	Belongs to the carbohydrate kinase PfkB family
BB268_RS07025	COG1349	DNA-binding transcription factor activity
BB268_RS07080	COG1837	Belongs to the UPF0109 family
BB268_RS07085	COG0228	four-way junction DNA binding
BB268_RS07090	COG0577	efflux transmembrane transporter activity
BB268_RS07095	COG1136	(ABC) transporter
BB268_RS07100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB268_RS07110	COG0505	Belongs to the CarA family
BB268_RS07120	COG0564	pseudouridine synthase activity
BB268_RS07130	COG0583	DNA-binding transcription factor activity
BB268_RS07135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BB268_RS07155	COG0301	tRNA thio-modification
BB268_RS07160	COG1104	cysteine desulfurase activity
BB268_RS07170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB268_RS07175	COG3679	Belongs to the UPF0342 family
BB268_RS07180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BB268_RS07195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BB268_RS07200	COG1368	sulfuric ester hydrolase activity
BB268_RS07205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BB268_RS07215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB268_RS07220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BB268_RS07245	COG2244	polysaccharide biosynthetic process
BB268_RS07250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB268_RS07255	COG1120	ATPase activity
BB268_RS07260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BB268_RS07265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB268_RS07270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB268_RS07285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BB268_RS07290	COG1253	flavin adenine dinucleotide binding
BB268_RS07295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BB268_RS07300	COG1242	4 iron, 4 sulfur cluster binding
BB268_RS07305	COG0671	phosphoesterase, PA-phosphatase related
BB268_RS07310	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BB268_RS07345	COG0297	glycogen (starch) synthase activity
BB268_RS07385	COG3475	LICD family
BB268_RS07400	COG0463	Glycosyl transferase, family 2
BB268_RS07405	COG1215	transferase activity, transferring glycosyl groups
BB268_RS07415	COG1091	dTDP-4-dehydrorhamnose reductase activity
BB268_RS07420	COG2151	metal-sulfur cluster biosynthetic enzyme
BB268_RS07425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB268_RS07430	COG0358	DNA primase activity
BB268_RS07435	COG1970	mechanosensitive ion channel activity
BB268_RS07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB268_RS07455	COG0004	ammonium transporteR
BB268_RS07465	COG1054	Belongs to the UPF0176 family
BB268_RS07475	COG2271	Major facilitator Superfamily
BB268_RS07480	COG0058	SHG alpha-glucan phosphorylase activity
BB268_RS07485	COG1640	4-alpha-glucanotransferase
BB268_RS07490	COG1609	Transcriptional regulator
BB268_RS07500	COG1175	transmembrane transport
BB268_RS07505	COG3833	ABC-type maltose transport systems, permease component
BB268_RS07510	COG3104	oligopeptide transport
BB268_RS07530	COG0438	transferase activity, transferring glycosyl groups
BB268_RS07535	COG0653	protein targeting
BB268_RS07555	COG0201	protein transport
BB268_RS07560	COG1442	glycosyl transferase family 8
BB268_RS07565	COG1216	Glycosyl transferase, family 2
BB268_RS07565	COG1442	glycosyl transferase family 8
BB268_RS07570	COG1442	glycosyl transferase family 8
BB268_RS07575	COG1442	glycosyl transferase family 8
BB268_RS07575	COG1216	Glycosyl transferase, family 2
BB268_RS07580	COG1442	glycosyl transferase family 8
BB268_RS07610	COG0765	amino acid transport
BB268_RS07615	COG1126	abc transporter atp-binding protein
BB268_RS07640	COG2309	aminopeptidase activity
BB268_RS07650	COG0154	amidase activity
BB268_RS07655	COG1187	pseudouridine synthase activity
BB268_RS07660	COG0656	L-ascorbic acid biosynthetic process
BB268_RS07665	COG0778	Nitroreductase
BB268_RS07670	COG0346	lactoylglutathione lyase activity
BB268_RS07675	COG0463	Glycosyl transferase, family 2
BB268_RS07680	COG1113	amino acid transport
BB268_RS07685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BB268_RS07690	COG0557	exoribonuclease II activity
BB268_RS07705	COG2814	Major facilitator Superfamily
BB268_RS07715	COG1131	(ABC) transporter
BB268_RS07720	COG0237	dephospho-CoA kinase activity
BB268_RS07725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB268_RS07730	COG1396	sequence-specific DNA binding
BB268_RS07785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BB268_RS07790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BB268_RS07815	COG1702	phosphate starvation-inducible protein PhoH
BB268_RS07830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB268_RS07840	COG0233	cytoplasmic translational termination
BB268_RS07855	COG0444	Belongs to the ABC transporter superfamily
BB268_RS07860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB268_RS07865	COG0601	transmembrane transport
BB268_RS07875	COG0081	regulation of translation
BB268_RS07880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BB268_RS07890	COG1473	amidohydrolase
BB268_RS07895	COG0583	DNA-binding transcription factor activity
BB268_RS07905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BB268_RS07910	COG1674	ftsk spoiiie
BB268_RS07915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BB268_RS07940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB268_RS07970	COG0673	inositol 2-dehydrogenase activity
BB268_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
BB268_RS08035	COG1114	Component of the transport system for branched-chain amino acids
BB268_RS08040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB268_RS08040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB268_RS08060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB268_RS08070	COG0708	Exodeoxyribonuclease III
BB268_RS08075	COG1393	Belongs to the ArsC family
BB268_RS08080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB268_RS08085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB268_RS08095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BB268_RS08125	COG0470	DNA polymerase III
BB268_RS08135	COG0517	IMP dehydrogenase activity
BB268_RS08175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BB268_RS08180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BB268_RS08190	COG0531	amino acid
BB268_RS08195	COG0569	domain protein
BB268_RS08210	COG1187	pseudouridine synthase activity
BB268_RS08220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB268_RS08225	COG0582	viral genome integration into host DNA
BB268_RS08245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BB268_RS08260	COG1827	regulation of RNA biosynthetic process
BB268_RS08275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB268_RS08280	COG1254	Belongs to the acylphosphatase family
BB268_RS08285	COG0706	membrane insertase activity
BB268_RS08290	COG0765	amino acid transport
BB268_RS08295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB268_RS08310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BB268_RS08320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB268_RS08345	COG1484	DNA-dependent DNA replication
BB268_RS08360	COG5002	protein histidine kinase activity
BB268_RS08365	COG0745	RESPONSE REGULATOR receiver
BB268_RS08375	COG0501	Belongs to the peptidase M48B family
BB268_RS08380	COG1704	LemA family
BB268_RS08385	COG0357	Ribosomal RNA small subunit methyltransferase G
BB268_RS08390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BB268_RS08395	COG0569	domain protein
BB268_RS08405	COG1122	ATPase activity
BB268_RS08415	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BB268_RS08420	COG1114	Component of the transport system for branched-chain amino acids
BB268_RS08425	COG1063	alcohol dehydrogenase
BB268_RS08450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB268_RS08455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BB268_RS08465	COG0217	transcriptional regulatory protein
BB268_RS08470	COG2376	Dihydroxyacetone kinase
BB268_RS08475	COG1309	transcriptional regulator
BB268_RS08485	COG2376	Dihydroxyacetone kinase
BB268_RS08490	COG1461	Dihydroxyacetone kinase
BB268_RS08495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BB268_RS08500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB268_RS08510	COG0789	Transcriptional regulator
BB268_RS08525	COG2226	methyltransferase
BB268_RS08530	COG0799	negative regulation of ribosome biogenesis
BB268_RS08540	COG1713	HD superfamily hydrolase involved in NAD metabolism
BB268_RS08545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB268_RS08550	COG1534	Rna-binding protein
BB268_RS08555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BB268_RS08560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BB268_RS08585	COG0574	Belongs to the PEP-utilizing enzyme family
BB268_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB268_RS08595	COG0517	IMP dehydrogenase activity
BB268_RS08605	COG1335	isochorismatase
BB268_RS08610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BB268_RS08615	COG0436	Aminotransferase
BB268_RS08620	COG0589	response to stress
BB268_RS08625	COG0561	phosphatase activity
BB268_RS08630	COG0252	asparaginase activity
BB268_RS08640	COG4989	oxidoreductase activity
BB268_RS08645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BB268_RS08650	COG3942	CHAP domain
BB268_RS08650	COG1705	Flagellar rod assembly protein muramidase FlgJ
BB268_RS08660	COG0736	holo-[acyl-carrier-protein] synthase activity
BB268_RS08665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB268_RS08675	COG1482	cell wall glycoprotein biosynthetic process
BB268_RS08680	COG1940	carbohydrate kinase activity
BB268_RS08685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB268_RS08685	COG2190	(PTS) system
BB268_RS08685	COG1263	PTS System
BB268_RS08690	COG1621	beta-fructofuranosidase activity
BB268_RS08695	COG1609	Transcriptional regulator
BB268_RS08700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB268_RS08710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB268_RS08760	COG2131	deaminase
BB268_RS08775	COG2814	Major facilitator Superfamily
BB268_RS08805	COG0629	single-stranded DNA binding
BB268_RS08810	COG0360	Binds together with S18 to 16S ribosomal RNA
BB268_RS08815	COG1194	a g-specific adenine glycosylase
BB268_RS08825	COG3118	belongs to the thioredoxin family
BB268_RS08855	COG0681	Belongs to the peptidase S26 family
BB268_RS08860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BB268_RS08875	COG1882	Formate acetyltransferase
BB268_RS08880	COG3576	pyridoxamine 5-phosphate
BB268_RS08885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB268_RS08900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB268_RS08910	COG2814	Major facilitator Superfamily
BB268_RS08915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB268_RS08930	COG0142	geranyltranstransferase activity
BB268_RS08935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BB268_RS08940	COG4988	ABC transporter
BB268_RS08945	COG1294	oxidase, subunit
BB268_RS08950	COG1271	oxidase subunit
BB268_RS08955	COG1252	NADH dehydrogenase
BB268_RS08990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB268_RS08995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB268_RS08995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB268_RS08995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BB268_RS09000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB268_RS09005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB268_RS09010	COG3711	transcriptional antiterminator
BB268_RS09010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB268_RS09030	COG4221	oxidoreductase activity
BB268_RS09050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BB268_RS09065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BB268_RS09070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB268_RS09075	COG0789	Transcriptional regulator
BB268_RS09090	COG2081	HI0933 family
BB268_RS09120	COG0456	acetyltransferase
BB268_RS09125	COG1214	PFAM Peptidase M22, glycoprotease
BB268_RS09140	COG3942	CHAP domain
BB268_RS09145	COG0174	glutamine synthetase
BB268_RS09150	COG0789	Transcriptional regulator
BB268_RS09165	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BB268_RS09190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BB268_RS09215	COG1162	GTPase activity
BB268_RS09240	COG0084	hydrolase, TatD family'
BB268_RS09265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BB268_RS09270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB268_RS09275	COG1696	Membrane protein involved in D-alanine export
BB268_RS09295	COG0745	RESPONSE REGULATOR receiver
BB268_RS09305	COG3314	Sporulation integral membrane protein YlbJ
BB268_RS09315	COG3448	diguanylate cyclase activity
BB268_RS09315	COG4175	Glycine betaine
BB268_RS09325	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BB268_RS09345	COG1070	Carbohydrate kinase
BB268_RS09355	COG3775	system Galactitol-specific IIC component
BB268_RS09360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB268_RS09370	COG1609	Transcriptional regulator
BB268_RS09455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB268_RS09460	COG1428	Deoxynucleoside kinase
BB268_RS09470	COG0542	response to heat
BB268_RS09475	COG4463	regulation of RNA biosynthetic process
BB268_RS09485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BB268_RS09495	COG0450	alkyl hydroperoxide reductase
BB268_RS09510	COG0025	NhaP-type Na H and K H
BB268_RS09520	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB268_RS09525	COG3590	peptidase
BB268_RS09555	COG1609	Transcriptional regulator
BB268_RS09580	COG2176	DNA-directed DNA polymerase activity
BB268_RS09585	COG1705	Flagellar rod assembly protein muramidase FlgJ
BB268_RS09585	COG1388	LysM domain
BB268_RS09600	COG4589	Belongs to the CDS family
BB268_RS09605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB268_RS09610	COG1862	Preprotein translocase
BB268_RS09630	COG3493	citrate carrier protein
BB268_RS09635	COG3290	protein histidine kinase activity
BB268_RS09640	COG4565	transcriptional regulatory protein
BB268_RS09645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB268_RS09655	COG3842	ATPase activity
BB268_RS09740	COG0737	Belongs to the 5'-nucleotidase family
BB268_RS09750	COG1363	Peptidase, m42
BB268_RS09765	COG4753	response regulator
BB268_RS09765	COG2207	Transcriptional regulator
BB268_RS09770	COG2972	Histidine kinase
BB268_RS09775	COG3716	PTS system mannose fructose sorbose family IID component
BB268_RS09780	COG3715	PTS system
BB268_RS09815	COG1131	(ABC) transporter
BB268_RS09825	COG2274	protein secretion by the type I secretion system
BB268_RS09830	COG3290	protein histidine kinase activity
BB268_RS09850	COG1263	PTS System
BB268_RS09850	COG2190	(PTS) system
BB268_RS09850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB268_RS09855	COG5002	protein histidine kinase activity
BB268_RS09860	COG0745	RESPONSE REGULATOR receiver
BB268_RS09870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BB268_RS09875	COG0581	inorganic phosphate transmembrane transporter activity
BB268_RS09880	COG0573	inorganic phosphate transmembrane transporter activity
BB268_RS09895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB268_RS09910	COG0789	Transcriptional regulator
BB268_RS09920	COG0494	nUDIX hydrolase
BB268_RS09935	COG0456	acetyltransferase
BB268_RS09940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BB268_RS09970	COG0582	viral genome integration into host DNA
BB268_RS09980	COG2946	Replication initiation factor
BB268_RS10005	COG2378	regulation of single-species biofilm formation
BB268_RS10010	COG0693	protein deglycase activity
BB268_RS10085	COG1131	(ABC) transporter
BB268_RS10125	COG1131	(ABC) transporter
BB268_RS10135	COG1396	sequence-specific DNA binding
BB268_RS10145	COG1694	Mazg nucleotide pyrophosphohydrolase
BB268_RS10150	COG1611	Belongs to the LOG family
BB268_RS10160	COG2897	thiosulfate sulfurtransferase activity
BB268_RS10175	COG0371	Dehydrogenase
BB268_RS10185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BB268_RS10185	COG0646	methionine synthase
BB268_RS10200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BB268_RS10215	COG2770	Histidine kinase
BB268_RS10215	COG2205	protein histidine kinase activity
BB268_RS10230	COG2814	Major facilitator Superfamily
BB268_RS10235	COG4667	esterase of the alpha-beta hydrolase superfamily
BB268_RS10245	COG4667	esterase of the alpha-beta hydrolase superfamily
BB268_RS10270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB268_RS10275	COG0564	pseudouridine synthase activity
BB268_RS10295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BB268_RS10300	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BB268_RS10320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB268_RS10325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB268_RS10325	COG1116	anion transmembrane transporter activity
BB268_RS10335	COG0561	phosphatase activity
BB268_RS10340	COG2514	catechol 2,3-dioxygenase activity
BB268_RS10350	COG0602	queuosine metabolic process
BB268_RS10370	COG1328	CTP reductase activity
BB268_RS10390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BB268_RS10400	COG1393	Belongs to the ArsC family
BB268_RS10405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BB268_RS10415	COG2818	Glycosylase
BB268_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BB268_RS10470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BB268_RS10490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB268_RS10545	COG0582	viral genome integration into host DNA
BB268_RS10620	COG0745	RESPONSE REGULATOR receiver
BB268_RS10625	COG5002	protein histidine kinase activity
BB268_RS10630	COG1288	antiporter activity
BB268_RS10640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BB268_RS10645	COG3852	Histidine kinase
BB268_RS10650	COG0784	Response regulator, receiver
BB268_RS10655	COG0517	IMP dehydrogenase activity
BB268_RS10655	COG1125	glycine betaine transport
BB268_RS10660	COG1174	glycine betaine transport
BB268_RS10665	COG0392	lysyltransferase activity
BB268_RS10665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BB268_RS10675	COG3759	membrane
BB268_RS10785	COG2314	TM2 domain
BB268_RS10805	COG0582	viral genome integration into host DNA
BB268_RS10820	COG0305	Participates in initiation and elongation during chromosome replication
BB268_RS10840	COG2095	MarC family integral membrane protein
BB268_RS10845	COG0482	sulfurtransferase activity
BB268_RS10850	COG1760	l-serine dehydratase
BB268_RS10855	COG1760	l-serine dehydratase
BB268_RS10860	COG0741	lytic transglycosylase activity
BB268_RS10885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB268_RS10890	COG0612	Peptidase, M16
BB268_RS10895	COG0612	Peptidase, M16
BB268_RS10900	COG2501	S4 domain
BB268_RS10920	COG0517	IMP dehydrogenase activity
BB268_RS10920	COG0516	GMP reductase activity
BB268_RS10930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB268_RS10945	COG0454	-acetyltransferase
BB268_RS10960	COG0549	Belongs to the carbamate kinase family
BB268_RS10975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BB268_RS10980	COG0488	(ABC) transporter
BB268_RS10985	COG4485	Bacterial membrane protein, YfhO
BB268_RS11005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BB268_RS11010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB268_RS11015	COG1475	DNA binding
BB268_RS11025	COG0592	DNA-directed DNA polymerase activity
BB268_RS11030	COG1597	lipid kinase activity
BB268_RS11045	COG0012	GTP binding
BB268_RS11055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BB268_RS11065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BB268_RS11095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins