locus-tag	class	description
CWQ21_RS00175	COG0436	Aminotransferase
CWQ21_RS00195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWQ21_RS00205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWQ21_RS00220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWQ21_RS00255	COG1175	transmembrane transport
CWQ21_RS00260	COG0395	ABC-type sugar transport system, permease component
CWQ21_RS00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWQ21_RS00285	COG3458	cephalosporin-C deacetylase activity
CWQ21_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWQ21_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWQ21_RS00330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWQ21_RS00340	COG2755	lipolytic protein G-D-S-L family
CWQ21_RS00340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWQ21_RS00345	COG1454	alcohol dehydrogenase
CWQ21_RS00345	COG1012	belongs to the aldehyde dehydrogenase family
CWQ21_RS00350	COG1064	alcohol dehydrogenase
CWQ21_RS00360	COG0534	Mate efflux family protein
CWQ21_RS00470	COG0201	protein transport
CWQ21_RS00490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWQ21_RS00500	COG0202	RNA polymerase activity
CWQ21_RS00660	COG3561	AntA/AntB antirepressor
CWQ21_RS00685	COG0556	nucleotide-excision repair
CWQ21_RS00775	COG1783	phage Terminase large subunit
CWQ21_RS00910	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWQ21_RS00925	COG0443	Heat shock 70 kDa protein
CWQ21_RS00935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWQ21_RS00945	COG0351	phosphomethylpyrimidine kinase
CWQ21_RS00950	COG4720	Psort location CytoplasmicMembrane, score
CWQ21_RS00960	COG0668	transmembrane transport
CWQ21_RS00990	COG0756	dUTP diphosphatase activity
CWQ21_RS01005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWQ21_RS01020	COG1879	ABC-type sugar transport system periplasmic component
CWQ21_RS01025	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWQ21_RS01040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWQ21_RS01045	COG1609	Transcriptional regulator
CWQ21_RS01055	COG0577	efflux transmembrane transporter activity
CWQ21_RS01060	COG1136	(ABC) transporter
CWQ21_RS01065	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS01070	COG5002	protein histidine kinase activity
CWQ21_RS01085	COG0191	fructose-bisphosphate aldolase activity
CWQ21_RS01105	COG1461	Dihydroxyacetone kinase
CWQ21_RS01140	COG1126	abc transporter atp-binding protein
CWQ21_RS01145	COG0765	amino acid transport
CWQ21_RS01165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWQ21_RS01175	COG0719	Fe-S assembly protein
CWQ21_RS01180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWQ21_RS01190	COG0719	Fe-S assembly protein
CWQ21_RS01195	COG1686	Belongs to the peptidase S11 family
CWQ21_RS01200	COG1686	Belongs to the peptidase S11 family
CWQ21_RS01205	COG4166	transmembrane transport
CWQ21_RS01210	COG0601	transmembrane transport
CWQ21_RS01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWQ21_RS01220	COG0444	Belongs to the ABC transporter superfamily
CWQ21_RS01225	COG4608	Belongs to the ABC transporter superfamily
CWQ21_RS01265	COG1121	(ABC) transporter
CWQ21_RS01270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWQ21_RS01285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWQ21_RS01285	COG4499	WXG100 protein secretion system (Wss), protein YukC
CWQ21_RS01310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWQ21_RS01315	COG1459	type II secretion system
CWQ21_RS01375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWQ21_RS01380	COG1363	Peptidase, m42
CWQ21_RS01395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWQ21_RS01400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWQ21_RS01415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWQ21_RS01435	COG1346	cytolysis
CWQ21_RS01450	COG0601	transmembrane transport
CWQ21_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWQ21_RS01460	COG1122	ATPase activity
CWQ21_RS01470	COG1263	PTS System
CWQ21_RS01470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWQ21_RS01475	COG0366	Alpha amylase catalytic
CWQ21_RS01480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWQ21_RS01495	COG3959	Transketolase, thiamine diphosphate binding domain
CWQ21_RS01500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CWQ21_RS01505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWQ21_RS01525	COG1045	serine acetyltransferase
CWQ21_RS01540	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CWQ21_RS01570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWQ21_RS01585	COG4974	Belongs to the 'phage' integrase family
CWQ21_RS01695	COG1396	sequence-specific DNA binding
CWQ21_RS01700	COG2814	Major facilitator Superfamily
CWQ21_RS01710	COG1732	Glycine betaine
CWQ21_RS01855	COG0519	Catalyzes the synthesis of GMP from XMP
CWQ21_RS01900	COG1695	Transcriptional regulator
CWQ21_RS01915	COG1755	Isoprenylcysteine carboxyl methyltransferase
CWQ21_RS01955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWQ21_RS01960	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWQ21_RS01980	COG1131	(ABC) transporter
CWQ21_RS01990	COG2190	(PTS) system
CWQ21_RS01990	COG1263	PTS System
CWQ21_RS01990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWQ21_RS01995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWQ21_RS02015	COG0768	penicillin binding
CWQ21_RS02025	COG0513	Belongs to the DEAD box helicase family
CWQ21_RS02040	COG1126	abc transporter atp-binding protein
CWQ21_RS02050	COG0492	ferredoxin-NADP+ reductase activity
CWQ21_RS02065	COG3579	cysteine-type endopeptidase activity
CWQ21_RS02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWQ21_RS02100	COG0116	Belongs to the methyltransferase superfamily
CWQ21_RS02110	COG1854	S-ribosylhomocysteine lyase activity
CWQ21_RS02115	COG1418	mRNA catabolic process
CWQ21_RS02115	COG4372	Transposase
CWQ21_RS02125	COG1131	(ABC) transporter
CWQ21_RS02135	COG4585	Histidine kinase
CWQ21_RS02140	COG2197	response regulator
CWQ21_RS02150	COG0194	GDP metabolic process
CWQ21_RS02160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWQ21_RS02165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWQ21_RS02170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWQ21_RS02170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWQ21_RS02180	COG2815	serine threonine protein kinase
CWQ21_RS02180	COG0515	serine threonine protein kinase
CWQ21_RS02190	COG4585	Histidine kinase
CWQ21_RS02195	COG2197	response regulator
CWQ21_RS02205	COG1098	S1 RNA binding domain
CWQ21_RS02210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWQ21_RS02215	COG1349	DNA-binding transcription factor activity
CWQ21_RS02225	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWQ21_RS02235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWQ21_RS02240	COG1882	Formate acetyltransferase
CWQ21_RS02260	COG1739	Uncharacterized protein family UPF0029
CWQ21_RS02265	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CWQ21_RS02270	COG1040	competence protein
CWQ21_RS02305	COG0527	aspartate kinase activity
CWQ21_RS02310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWQ21_RS02320	COG1024	Enoyl-CoA hydratase
CWQ21_RS02330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWQ21_RS02340	COG2070	2-Nitropropane dioxygenase
CWQ21_RS02345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWQ21_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
CWQ21_RS02355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWQ21_RS02370	COG0439	Biotin carboxylase
CWQ21_RS02390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CWQ21_RS02405	COG3716	PTS system mannose fructose sorbose family IID component
CWQ21_RS02410	COG3715	PTS system
CWQ21_RS02425	COG0561	phosphatase activity
CWQ21_RS02440	COG2252	PERMEase
CWQ21_RS02445	COG0802	atpase or kinase
CWQ21_RS02455	COG1316	TRANSCRIPTIONal
CWQ21_RS02465	COG0537	adenosine 5'-monophosphoramidase activity
CWQ21_RS02480	COG1131	(ABC) transporter
CWQ21_RS02485	COG4473	ABC transporter
CWQ21_RS02495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CWQ21_RS02510	COG0195	Participates in both transcription termination and antitermination
CWQ21_RS02515	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CWQ21_RS02525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWQ21_RS02530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWQ21_RS02555	COG2860	membrane
CWQ21_RS02565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWQ21_RS02565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWQ21_RS02570	COG1832	CoA-binding protein
CWQ21_RS02590	COG5002	protein histidine kinase activity
CWQ21_RS02610	COG1268	BioY protein
CWQ21_RS02615	COG1234	tRNA 3'-trailer cleavage
CWQ21_RS02630	COG0166	Belongs to the GPI family
CWQ21_RS02635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWQ21_RS02640	COG0457	Tetratricopeptide repeat
CWQ21_RS02640	COG0705	Rhomboid family
CWQ21_RS02645	COG1744	ABC transporter substrate-binding protein PnrA-like
CWQ21_RS02650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWQ21_RS02665	COG0706	membrane insertase activity
CWQ21_RS02725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWQ21_RS02735	COG2153	protein acetylation
CWQ21_RS02745	COG1216	Glycosyl transferase, family 2
CWQ21_RS02745	COG1442	glycosyl transferase family 8
CWQ21_RS02790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWQ21_RS02800	COG0789	Transcriptional regulator
CWQ21_RS02810	COG0656	L-ascorbic acid biosynthetic process
CWQ21_RS02855	COG2226	methyltransferase
CWQ21_RS02865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWQ21_RS02870	COG3414	Phosphotransferase system galactitol-specific IIB component
CWQ21_RS02875	COG3775	system Galactitol-specific IIC component
CWQ21_RS02880	COG0235	Class ii aldolase
CWQ21_RS02890	COG3775	system Galactitol-specific IIC component
CWQ21_RS02895	COG3414	Phosphotransferase system galactitol-specific IIB component
CWQ21_RS02900	COG2207	Transcriptional regulator
CWQ21_RS02915	COG1175	transmembrane transport
CWQ21_RS02930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWQ21_RS02940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWQ21_RS02945	COG2017	converts alpha-aldose to the beta-anomer
CWQ21_RS03010	COG1518	maintenance of DNA repeat elements
CWQ21_RS03015	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWQ21_RS03020	COG0673	inositol 2-dehydrogenase activity
CWQ21_RS03030	COG2315	Protein conserved in bacteria
CWQ21_RS03045	COG0742	ribosomal rna small subunit methyltransferase
CWQ21_RS03060	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWQ21_RS03065	COG0737	Belongs to the 5'-nucleotidase family
CWQ21_RS03070	COG4470	Protein conserved in bacteria
CWQ21_RS03085	COG1132	(ABC) transporter
CWQ21_RS03090	COG1132	(ABC) transporter
CWQ21_RS03095	COG0512	Glutamine amidotransferase of anthranilate synthase
CWQ21_RS03100	COG1268	BioY protein
CWQ21_RS03105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CWQ21_RS03125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWQ21_RS03140	COG1940	carbohydrate kinase activity
CWQ21_RS03145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWQ21_RS03150	COG1217	gtp-binding protein TYPA
CWQ21_RS03160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CWQ21_RS03185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWQ21_RS03195	COG0762	integral membrane protein
CWQ21_RS03200	COG2302	S4 RNA-binding domain
CWQ21_RS03205	COG3599	regulation of cell shape
CWQ21_RS03220	COG0494	nUDIX hydrolase
CWQ21_RS03225	COG0542	response to heat
CWQ21_RS03235	COG4703	Protein of unknown function (DUF1797)
CWQ21_RS03240	COG0765	amino acid transport
CWQ21_RS03245	COG1126	abc transporter atp-binding protein
CWQ21_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWQ21_RS03260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWQ21_RS03265	COG1570	exodeoxyribonuclease VII activity
CWQ21_RS03270	COG1722	exodeoxyribonuclease VII activity
CWQ21_RS03280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CWQ21_RS03285	COG1438	arginine binding
CWQ21_RS03290	COG0497	DNA recombination
CWQ21_RS03295	COG1307	EDD domain protein, DegV family
CWQ21_RS03300	COG2755	lipolytic protein G-D-S-L family
CWQ21_RS03345	COG1078	dGTPase activity
CWQ21_RS03370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWQ21_RS03380	COG2884	Cell division ATP-binding protein ftsE
CWQ21_RS03385	COG2177	Part of the ABC transporter FtsEX involved in
CWQ21_RS03405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWQ21_RS03405	COG1199	ATP-dependent helicase activity
CWQ21_RS03410	COG0436	Aminotransferase
CWQ21_RS03415	COG0017	Asparaginyl-tRNA synthetase
CWQ21_RS03440	COG1660	Displays ATPase and GTPase activities
CWQ21_RS03465	COG0254	rRNA binding
CWQ21_RS03470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWQ21_RS03475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CWQ21_RS03480	COG0716	FMN binding
CWQ21_RS03485	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CWQ21_RS03485	COG1605	Chorismate mutase
CWQ21_RS03490	COG0038	chloride channel
CWQ21_RS03495	COG0335	large ribosomal subunit rRNA binding
CWQ21_RS03545	COG1136	(ABC) transporter
CWQ21_RS03580	COG0772	Belongs to the SEDS family
CWQ21_RS03600	COG0560	Phosphoserine phosphatase
CWQ21_RS03615	COG0148	phosphopyruvate hydratase activity
CWQ21_RS03635	COG1316	TRANSCRIPTIONal
CWQ21_RS03650	COG3700	Belongs to the class B bacterial acid phosphatase family
CWQ21_RS03755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWQ21_RS03760	COG4555	ABC transporter
CWQ21_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
CWQ21_RS03795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWQ21_RS03800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWQ21_RS03820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWQ21_RS03825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWQ21_RS03845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CWQ21_RS03845	COG3064	Membrane
CWQ21_RS03860	COG3590	peptidase
CWQ21_RS03865	COG3590	peptidase
CWQ21_RS03915	COG1136	(ABC) transporter
CWQ21_RS03930	COG0586	Pfam SNARE associated Golgi protein
CWQ21_RS03935	COG4619	ABC transporter
CWQ21_RS03940	COG0390	transport system, permease component
CWQ21_RS03950	COG0583	DNA-binding transcription factor activity
CWQ21_RS03965	COG2211	Major facilitator Superfamily
CWQ21_RS03975	COG3250	beta-galactosidase activity
CWQ21_RS03980	COG2186	Transcriptional regulator
CWQ21_RS03990	COG0800	Aldolase
CWQ21_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
CWQ21_RS04025	COG1609	Transcriptional regulator
CWQ21_RS04040	COG0438	transferase activity, transferring glycosyl groups
CWQ21_RS04065	COG0765	amino acid transport
CWQ21_RS04070	COG0765	amino acid transport
CWQ21_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWQ21_RS04080	COG1126	abc transporter atp-binding protein
CWQ21_RS04085	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS04090	COG5002	protein histidine kinase activity
CWQ21_RS04095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWQ21_RS04100	COG2832	Protein of unknown function (DUF454)
CWQ21_RS04110	COG1196	nuclear chromosome segregation
CWQ21_RS04115	COG0561	phosphatase activity
CWQ21_RS04120	COG0561	phosphatase activity
CWQ21_RS04125	COG0552	protein localization to endoplasmic reticulum
CWQ21_RS04130	COG3689	TIGRFAM TIGR03943 family protein
CWQ21_RS04135	COG0701	Predicted permease
CWQ21_RS04150	COG2183	response to ionizing radiation
CWQ21_RS04155	COG3091	SprT-like family
CWQ21_RS04160	COG1983	PspC domain protein
CWQ21_RS04200	COG0826	peptidase U32
CWQ21_RS04205	COG4443	Transcriptional Coactivator p15 (PC4)
CWQ21_RS04215	COG1914	H( )-stimulated, divalent metal cation uptake system
CWQ21_RS04230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWQ21_RS04230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWQ21_RS04255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWQ21_RS04280	COG1164	Oligoendopeptidase f
CWQ21_RS04290	COG0772	Belongs to the SEDS family
CWQ21_RS04310	COG0768	penicillin binding
CWQ21_RS04325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWQ21_RS04330	COG2223	nitrite transmembrane transporter activity
CWQ21_RS04360	COG2011	ABC-type metal ion transport system permease component
CWQ21_RS04365	COG1464	Belongs to the NlpA lipoprotein family
CWQ21_RS04370	COG0513	Belongs to the DEAD box helicase family
CWQ21_RS04380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWQ21_RS04385	COG0204	Acyl-transferase
CWQ21_RS04390	COG1555	photosystem II stabilization
CWQ21_RS04390	COG1596	polysaccharide export
CWQ21_RS04395	COG2333	competence protein COMEC
CWQ21_RS04395	COG0658	competence protein
CWQ21_RS04400	COG0561	phosphatase activity
CWQ21_RS04405	COG1609	Transcriptional regulator
CWQ21_RS04410	COG0657	acetylesterase activity
CWQ21_RS04415	COG2226	methyltransferase
CWQ21_RS04425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWQ21_RS04430	COG3711	transcriptional antiterminator
CWQ21_RS04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWQ21_RS04435	COG2190	(PTS) system
CWQ21_RS04435	COG1263	PTS System
CWQ21_RS04445	COG3835	regulator
CWQ21_RS04450	COG1929	Belongs to the glycerate kinase type-1 family
CWQ21_RS04455	COG2610	gluconate transmembrane transporter activity
CWQ21_RS04465	COG1846	Transcriptional regulator
CWQ21_RS04480	COG0363	glucosamine-6-phosphate deaminase activity
CWQ21_RS04485	COG0435	Glutathione S-transferase
CWQ21_RS04490	COG1187	pseudouridine synthase activity
CWQ21_RS04515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWQ21_RS04520	COG4122	O-methyltransferase activity
CWQ21_RS04530	COG4894	glucomannan catabolic process
CWQ21_RS04540	COG1811	Na channel or pump
CWQ21_RS04545	COG1442	glycosyl transferase family 8
CWQ21_RS04560	COG1476	TRANSCRIPTIONal
CWQ21_RS04575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWQ21_RS04580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWQ21_RS04585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWQ21_RS04600	COG1012	belongs to the aldehyde dehydrogenase family
CWQ21_RS04605	COG0726	polysaccharide deacetylase
CWQ21_RS04620	COG1956	GAF domain-containing protein
CWQ21_RS04625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWQ21_RS04635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CWQ21_RS04635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CWQ21_RS04665	COG4721	ABC-type cobalt transport system, permease component
CWQ21_RS04670	COG1122	ATPase activity
CWQ21_RS04680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CWQ21_RS04710	COG4109	DRTGG domain
CWQ21_RS04715	COG0024	Methionine aminopeptidase
CWQ21_RS04725	COG2246	polysaccharide biosynthetic process
CWQ21_RS04730	COG4708	membrane
CWQ21_RS04740	COG1597	lipid kinase activity
CWQ21_RS04745	COG1523	belongs to the glycosyl hydrolase 13 family
CWQ21_RS04760	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CWQ21_RS04840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWQ21_RS04840	COG0072	phenylalanine-tRNA ligase activity
CWQ21_RS04845	COG2321	neutral zinc metallopeptidase
CWQ21_RS04870	COG0488	(ABC) transporter
CWQ21_RS04875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWQ21_RS04880	COG0022	dehydrogenase e1 component
CWQ21_RS04880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWQ21_RS04885	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWQ21_RS04895	COG0095	Lipoate-protein ligase
CWQ21_RS04900	COG3442	glutamine amidotransferase
CWQ21_RS04905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWQ21_RS04910	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CWQ21_RS04935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWQ21_RS04945	COG0647	UMP catabolic process
CWQ21_RS04955	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CWQ21_RS04960	COG1518	maintenance of DNA repeat elements
CWQ21_RS04965	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWQ21_RS04985	COG0481	GTPase activity
CWQ21_RS04995	COG1418	mRNA catabolic process
CWQ21_RS05000	COG0456	acetyltransferase
CWQ21_RS05010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWQ21_RS05040	COG1131	(ABC) transporter
CWQ21_RS05045	COG1725	Transcriptional regulator
CWQ21_RS05055	COG0205	6-phosphofructokinase activity
CWQ21_RS05060	COG0469	pyruvate kinase activity
CWQ21_RS05075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWQ21_RS05080	COG2824	Alkylphosphonate utilization operon protein PhnA
CWQ21_RS05085	COG0765	amino acid transport
CWQ21_RS05090	COG1126	abc transporter atp-binding protein
CWQ21_RS05105	COG1072	(Pantothenic acid kinase))
CWQ21_RS05110	COG2813	Specifically methylates the guanine in position
CWQ21_RS05120	COG1744	ABC transporter substrate-binding protein PnrA-like
CWQ21_RS05125	COG3845	ABC transporter
CWQ21_RS05130	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWQ21_RS05135	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWQ21_RS05155	COG3764	Sortase (surface protein transpeptidase)
CWQ21_RS05160	COG0346	lactoylglutathione lyase activity
CWQ21_RS05185	COG2188	Transcriptional regulator
CWQ21_RS05200	COG1464	Belongs to the NlpA lipoprotein family
CWQ21_RS05215	COG1136	(ABC) transporter
CWQ21_RS05225	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS05230	COG5002	protein histidine kinase activity
CWQ21_RS05235	COG4974	Belongs to the 'phage' integrase family
CWQ21_RS05240	COG4166	transmembrane transport
CWQ21_RS05255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWQ21_RS05260	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CWQ21_RS05265	COG5002	protein histidine kinase activity
CWQ21_RS05270	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS05280	COG0704	Plays a role in the regulation of phosphate uptake
CWQ21_RS05285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWQ21_RS05290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWQ21_RS05295	COG0581	inorganic phosphate transmembrane transporter activity
CWQ21_RS05300	COG0573	inorganic phosphate transmembrane transporter activity
CWQ21_RS05310	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CWQ21_RS05310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWQ21_RS05315	COG0483	inositol monophosphate 1-phosphatase activity
CWQ21_RS05330	COG0196	riboflavin kinase activity
CWQ21_RS05335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWQ21_RS05365	COG1136	(ABC) transporter
CWQ21_RS05370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWQ21_RS05375	COG0758	DNA mediated transformation
CWQ21_RS05380	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CWQ21_RS05385	COG4604	ABC transporter, ATP-binding protein
CWQ21_RS05390	COG4605	iron ion homeostasis
CWQ21_RS05395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWQ21_RS05400	COG0110	maltose O-acetyltransferase activity
CWQ21_RS05410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWQ21_RS05415	COG1376	ErfK ybiS ycfS ynhG family protein
CWQ21_RS05420	COG1966	Carbon starvation protein
CWQ21_RS05425	COG3279	Response regulator of the LytR AlgR family
CWQ21_RS05430	COG3275	phosphorelay sensor kinase activity
CWQ21_RS05545	COG0505	Belongs to the CarA family
CWQ21_RS05555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWQ21_RS05575	COG0488	(ABC) transporter
CWQ21_RS05600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWQ21_RS05640	COG0095	Lipoate-protein ligase
CWQ21_RS05650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWQ21_RS05655	COG4684	Psort location CytoplasmicMembrane, score
CWQ21_RS05660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWQ21_RS05670	COG1132	(ABC) transporter
CWQ21_RS05700	COG2890	protein-(glutamine-N5) methyltransferase activity
CWQ21_RS05715	COG1942	4-Oxalocrotonate Tautomerase
CWQ21_RS05735	COG0431	NADPH-dependent FMN reductase
CWQ21_RS05735	COG1053	succinate dehydrogenase
CWQ21_RS05735	COG3976	FMN-binding domain protein
CWQ21_RS05745	COG2233	PERMEase
CWQ21_RS05760	COG0477	Major facilitator Superfamily
CWQ21_RS05775	COG4221	oxidoreductase activity
CWQ21_RS05780	COG0280	phosphate acetyltransferase
CWQ21_RS05785	COG0564	pseudouridine synthase activity
CWQ21_RS05790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWQ21_RS05795	COG2357	RelA SpoT domain protein
CWQ21_RS05810	COG1104	cysteine desulfurase activity
CWQ21_RS05820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CWQ21_RS05825	COG2003	Belongs to the UPF0758 family
CWQ21_RS05830	COG0628	permease
CWQ21_RS05835	COG2723	6-phospho-beta-galactosidase activity
CWQ21_RS05845	COG0561	phosphatase activity
CWQ21_RS05860	COG0038	chloride channel
CWQ21_RS05870	COG1177	transmembrane transport
CWQ21_RS05875	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWQ21_RS05885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWQ21_RS05890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CWQ21_RS05910	COG0285	dihydrofolate synthase activity
CWQ21_RS05915	COG2962	Rard protein
CWQ21_RS05930	COG0726	polysaccharide deacetylase
CWQ21_RS05955	COG1012	belongs to the aldehyde dehydrogenase family
CWQ21_RS06030	COG2261	transglycosylase associated protein
CWQ21_RS06055	COG1115	amino acid carrier protein
CWQ21_RS06060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWQ21_RS06070	COG1346	cytolysis
CWQ21_RS06085	COG0539	negative regulation of cytoplasmic translation
CWQ21_RS06105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWQ21_RS06115	COG0187	DNA topoisomerase II activity
CWQ21_RS06120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CWQ21_RS06135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWQ21_RS06145	COG1083	cytidylyl-transferase
CWQ21_RS06145	COG2755	lipolytic protein G-D-S-L family
CWQ21_RS06160	COG2089	acid synthase
CWQ21_RS06175	COG1216	Glycosyl transferase, family 2
CWQ21_RS06175	COG1442	glycosyl transferase family 8
CWQ21_RS06180	COG1442	glycosyl transferase family 8
CWQ21_RS06180	COG1216	Glycosyl transferase, family 2
CWQ21_RS06195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWQ21_RS06220	COG1316	TRANSCRIPTIONal
CWQ21_RS06245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CWQ21_RS06260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CWQ21_RS06280	COG3842	ATPase activity
CWQ21_RS06295	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CWQ21_RS06300	COG3527	Alpha-acetolactate decarboxylase
CWQ21_RS06305	COG0028	Belongs to the TPP enzyme family
CWQ21_RS06310	COG0457	Tetratricopeptide repeat
CWQ21_RS06315	COG0628	permease
CWQ21_RS06325	COG1051	belongs to the nudix hydrolase family
CWQ21_RS06565	COG3561	AntA/AntB antirepressor
CWQ21_RS06575	COG2932	Transcriptional regulator
CWQ21_RS06585	COG2314	TM2 domain
CWQ21_RS06595	COG5492	domain, Protein
CWQ21_RS06600	COG1088	dTDP-glucose 4,6-dehydratase activity
CWQ21_RS06610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWQ21_RS06615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWQ21_RS06625	COG2384	SAM-dependent methyltransferase
CWQ21_RS06650	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWQ21_RS06650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWQ21_RS06655	COG0300	oxidoreductase activity
CWQ21_RS06700	COG1573	uracil-dna glycosylase
CWQ21_RS06705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWQ21_RS06715	COG0584	glycerophosphoryl diester phosphodiesterase
CWQ21_RS06720	COG0322	excinuclease ABC activity
CWQ21_RS06730	COG0534	Mate efflux family protein
CWQ21_RS06770	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWQ21_RS06790	COG2176	DNA-directed DNA polymerase activity
CWQ21_RS06800	COG4974	Belongs to the 'phage' integrase family
CWQ21_RS06830	COG1674	ftsk spoiiie
CWQ21_RS06875	COG2040	homocysteine
CWQ21_RS06880	COG0833	amino acid
CWQ21_RS06920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWQ21_RS06930	COG3425	synthase
CWQ21_RS06945	COG1272	protein, Hemolysin III
CWQ21_RS06990	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS06995	COG2357	RelA SpoT domain protein
CWQ21_RS07000	COG1132	(ABC) transporter
CWQ21_RS07015	COG0737	Belongs to the 5'-nucleotidase family
CWQ21_RS07020	COG0242	peptide deformylase activity
CWQ21_RS07025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWQ21_RS07035	COG1132	(ABC) transporter
CWQ21_RS07050	COG0488	(ABC) transporter
CWQ21_RS07080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWQ21_RS07080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWQ21_RS07080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWQ21_RS07085	COG1105	Belongs to the carbohydrate kinase PfkB family
CWQ21_RS07090	COG1349	DNA-binding transcription factor activity
CWQ21_RS07145	COG1837	Belongs to the UPF0109 family
CWQ21_RS07150	COG0228	four-way junction DNA binding
CWQ21_RS07155	COG0577	efflux transmembrane transporter activity
CWQ21_RS07160	COG1136	(ABC) transporter
CWQ21_RS07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWQ21_RS07175	COG0505	Belongs to the CarA family
CWQ21_RS07185	COG0564	pseudouridine synthase activity
CWQ21_RS07195	COG0583	DNA-binding transcription factor activity
CWQ21_RS07200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWQ21_RS07220	COG0301	tRNA thio-modification
CWQ21_RS07225	COG1104	cysteine desulfurase activity
CWQ21_RS07235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWQ21_RS07240	COG3679	Belongs to the UPF0342 family
CWQ21_RS07245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWQ21_RS07260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWQ21_RS07265	COG1368	sulfuric ester hydrolase activity
CWQ21_RS07270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWQ21_RS07280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWQ21_RS07285	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWQ21_RS07310	COG2244	polysaccharide biosynthetic process
CWQ21_RS07315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWQ21_RS07320	COG1120	ATPase activity
CWQ21_RS07325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWQ21_RS07330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWQ21_RS07335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWQ21_RS07350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWQ21_RS07355	COG1253	flavin adenine dinucleotide binding
CWQ21_RS07360	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CWQ21_RS07365	COG1242	4 iron, 4 sulfur cluster binding
CWQ21_RS07370	COG0671	phosphoesterase, PA-phosphatase related
CWQ21_RS07375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CWQ21_RS07410	COG0297	glycogen (starch) synthase activity
CWQ21_RS07465	COG0463	Glycosyl transferase, family 2
CWQ21_RS07470	COG1215	transferase activity, transferring glycosyl groups
CWQ21_RS07480	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWQ21_RS07485	COG2151	metal-sulfur cluster biosynthetic enzyme
CWQ21_RS07490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWQ21_RS07495	COG0358	DNA primase activity
CWQ21_RS07500	COG1970	mechanosensitive ion channel activity
CWQ21_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWQ21_RS07520	COG0004	ammonium transporteR
CWQ21_RS07530	COG1054	Belongs to the UPF0176 family
CWQ21_RS07540	COG2271	Major facilitator Superfamily
CWQ21_RS07550	COG0058	SHG alpha-glucan phosphorylase activity
CWQ21_RS07555	COG1640	4-alpha-glucanotransferase
CWQ21_RS07560	COG1609	Transcriptional regulator
CWQ21_RS07570	COG1175	transmembrane transport
CWQ21_RS07575	COG3833	ABC-type maltose transport systems, permease component
CWQ21_RS07580	COG3104	oligopeptide transport
CWQ21_RS07600	COG0438	transferase activity, transferring glycosyl groups
CWQ21_RS07605	COG0653	protein targeting
CWQ21_RS07625	COG0201	protein transport
CWQ21_RS07630	COG1442	glycosyl transferase family 8
CWQ21_RS07635	COG1216	Glycosyl transferase, family 2
CWQ21_RS07635	COG1442	glycosyl transferase family 8
CWQ21_RS07640	COG1442	glycosyl transferase family 8
CWQ21_RS07645	COG1216	Glycosyl transferase, family 2
CWQ21_RS07645	COG1442	glycosyl transferase family 8
CWQ21_RS07650	COG1442	glycosyl transferase family 8
CWQ21_RS07680	COG0765	amino acid transport
CWQ21_RS07685	COG1126	abc transporter atp-binding protein
CWQ21_RS07710	COG2309	aminopeptidase activity
CWQ21_RS07720	COG0154	amidase activity
CWQ21_RS07725	COG1187	pseudouridine synthase activity
CWQ21_RS07730	COG0656	L-ascorbic acid biosynthetic process
CWQ21_RS07735	COG0778	Nitroreductase
CWQ21_RS07740	COG0346	lactoylglutathione lyase activity
CWQ21_RS07745	COG0463	Glycosyl transferase, family 2
CWQ21_RS07750	COG1113	amino acid transport
CWQ21_RS07755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CWQ21_RS07760	COG0557	exoribonuclease II activity
CWQ21_RS07775	COG2814	Major facilitator Superfamily
CWQ21_RS07785	COG1131	(ABC) transporter
CWQ21_RS07790	COG0237	dephospho-CoA kinase activity
CWQ21_RS07795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWQ21_RS07800	COG1396	sequence-specific DNA binding
CWQ21_RS07855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CWQ21_RS07860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CWQ21_RS07890	COG1702	phosphate starvation-inducible protein PhoH
CWQ21_RS07905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWQ21_RS07915	COG0233	cytoplasmic translational termination
CWQ21_RS07930	COG0444	Belongs to the ABC transporter superfamily
CWQ21_RS07935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWQ21_RS07940	COG0601	transmembrane transport
CWQ21_RS07945	COG0747	negative chemotaxis
CWQ21_RS07950	COG0081	regulation of translation
CWQ21_RS07955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CWQ21_RS07965	COG1473	amidohydrolase
CWQ21_RS07970	COG0583	DNA-binding transcription factor activity
CWQ21_RS07980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWQ21_RS07985	COG1674	ftsk spoiiie
CWQ21_RS07990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CWQ21_RS08015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWQ21_RS08050	COG0673	inositol 2-dehydrogenase activity
CWQ21_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
CWQ21_RS08120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWQ21_RS08120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWQ21_RS08140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWQ21_RS08150	COG0708	Exodeoxyribonuclease III
CWQ21_RS08155	COG1393	Belongs to the ArsC family
CWQ21_RS08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWQ21_RS08165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWQ21_RS08175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CWQ21_RS08205	COG0470	DNA polymerase III
CWQ21_RS08215	COG0517	IMP dehydrogenase activity
CWQ21_RS08255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWQ21_RS08260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWQ21_RS08270	COG0531	amino acid
CWQ21_RS08275	COG0569	domain protein
CWQ21_RS08290	COG1187	pseudouridine synthase activity
CWQ21_RS08300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWQ21_RS08305	COG0582	viral genome integration into host DNA
CWQ21_RS08325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CWQ21_RS08340	COG1827	regulation of RNA biosynthetic process
CWQ21_RS08355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWQ21_RS08360	COG1254	Belongs to the acylphosphatase family
CWQ21_RS08365	COG0706	membrane insertase activity
CWQ21_RS08370	COG0765	amino acid transport
CWQ21_RS08375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWQ21_RS08390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWQ21_RS08400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWQ21_RS08425	COG1484	DNA-dependent DNA replication
CWQ21_RS08440	COG5002	protein histidine kinase activity
CWQ21_RS08445	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS08455	COG0501	Belongs to the peptidase M48B family
CWQ21_RS08460	COG1704	LemA family
CWQ21_RS08465	COG0357	Ribosomal RNA small subunit methyltransferase G
CWQ21_RS08470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWQ21_RS08475	COG0569	domain protein
CWQ21_RS08485	COG1122	ATPase activity
CWQ21_RS08495	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CWQ21_RS08500	COG1114	Component of the transport system for branched-chain amino acids
CWQ21_RS08505	COG1063	alcohol dehydrogenase
CWQ21_RS08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWQ21_RS08535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWQ21_RS08545	COG0217	transcriptional regulatory protein
CWQ21_RS08555	COG2376	Dihydroxyacetone kinase
CWQ21_RS08560	COG1309	transcriptional regulator
CWQ21_RS08570	COG2376	Dihydroxyacetone kinase
CWQ21_RS08575	COG1461	Dihydroxyacetone kinase
CWQ21_RS08580	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CWQ21_RS08585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWQ21_RS08595	COG0789	Transcriptional regulator
CWQ21_RS08610	COG2226	methyltransferase
CWQ21_RS08615	COG0799	negative regulation of ribosome biogenesis
CWQ21_RS08625	COG1713	HD superfamily hydrolase involved in NAD metabolism
CWQ21_RS08630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWQ21_RS08635	COG1534	Rna-binding protein
CWQ21_RS08640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWQ21_RS08645	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CWQ21_RS08670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWQ21_RS08670	COG0574	Belongs to the PEP-utilizing enzyme family
CWQ21_RS08680	COG0517	IMP dehydrogenase activity
CWQ21_RS08690	COG1335	isochorismatase
CWQ21_RS08695	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CWQ21_RS08700	COG0436	Aminotransferase
CWQ21_RS08710	COG0561	phosphatase activity
CWQ21_RS08715	COG0252	asparaginase activity
CWQ21_RS08725	COG4989	oxidoreductase activity
CWQ21_RS08730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWQ21_RS08735	COG3942	CHAP domain
CWQ21_RS08735	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWQ21_RS08745	COG0736	holo-[acyl-carrier-protein] synthase activity
CWQ21_RS08750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWQ21_RS08760	COG1482	cell wall glycoprotein biosynthetic process
CWQ21_RS08765	COG1940	carbohydrate kinase activity
CWQ21_RS08770	COG1263	PTS System
CWQ21_RS08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWQ21_RS08770	COG2190	(PTS) system
CWQ21_RS08775	COG1621	beta-fructofuranosidase activity
CWQ21_RS08780	COG1609	Transcriptional regulator
CWQ21_RS08785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWQ21_RS08795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWQ21_RS08845	COG2131	deaminase
CWQ21_RS08860	COG2814	Major facilitator Superfamily
CWQ21_RS08890	COG0629	single-stranded DNA binding
CWQ21_RS08895	COG0360	Binds together with S18 to 16S ribosomal RNA
CWQ21_RS08900	COG1194	a g-specific adenine glycosylase
CWQ21_RS08910	COG3118	belongs to the thioredoxin family
CWQ21_RS08940	COG0681	Belongs to the peptidase S26 family
CWQ21_RS08945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWQ21_RS08960	COG1882	Formate acetyltransferase
CWQ21_RS08965	COG3576	pyridoxamine 5-phosphate
CWQ21_RS08970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWQ21_RS08985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWQ21_RS08995	COG2814	Major facilitator Superfamily
CWQ21_RS09000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWQ21_RS09015	COG0142	geranyltranstransferase activity
CWQ21_RS09020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CWQ21_RS09025	COG4988	ABC transporter
CWQ21_RS09030	COG1294	oxidase, subunit
CWQ21_RS09035	COG1271	oxidase subunit
CWQ21_RS09040	COG1252	NADH dehydrogenase
CWQ21_RS09080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWQ21_RS09085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWQ21_RS09085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWQ21_RS09085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CWQ21_RS09090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWQ21_RS09095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWQ21_RS09100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWQ21_RS09100	COG3711	transcriptional antiterminator
CWQ21_RS09120	COG4221	oxidoreductase activity
CWQ21_RS09135	COG0656	L-ascorbic acid biosynthetic process
CWQ21_RS09140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CWQ21_RS09155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CWQ21_RS09160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CWQ21_RS09165	COG0789	Transcriptional regulator
CWQ21_RS09180	COG2081	HI0933 family
CWQ21_RS09210	COG0456	acetyltransferase
CWQ21_RS09215	COG1214	PFAM Peptidase M22, glycoprotease
CWQ21_RS09230	COG3942	CHAP domain
CWQ21_RS09235	COG0174	glutamine synthetase
CWQ21_RS09240	COG0789	Transcriptional regulator
CWQ21_RS09255	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CWQ21_RS09285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWQ21_RS09310	COG1162	GTPase activity
CWQ21_RS09335	COG0084	hydrolase, TatD family'
CWQ21_RS09360	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CWQ21_RS09365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWQ21_RS09370	COG1696	Membrane protein involved in D-alanine export
CWQ21_RS09390	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS09400	COG3314	Sporulation integral membrane protein YlbJ
CWQ21_RS09410	COG4175	Glycine betaine
CWQ21_RS09410	COG3448	diguanylate cyclase activity
CWQ21_RS09420	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CWQ21_RS09440	COG1070	Carbohydrate kinase
CWQ21_RS09450	COG3775	system Galactitol-specific IIC component
CWQ21_RS09455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWQ21_RS09465	COG1609	Transcriptional regulator
CWQ21_RS09550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWQ21_RS09555	COG1428	Deoxynucleoside kinase
CWQ21_RS09565	COG0542	response to heat
CWQ21_RS09570	COG4463	regulation of RNA biosynthetic process
CWQ21_RS09580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWQ21_RS09590	COG0450	alkyl hydroperoxide reductase
CWQ21_RS09605	COG0025	NhaP-type Na H and K H
CWQ21_RS09615	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWQ21_RS09620	COG3590	peptidase
CWQ21_RS09650	COG1609	Transcriptional regulator
CWQ21_RS09675	COG2176	DNA-directed DNA polymerase activity
CWQ21_RS09680	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWQ21_RS09680	COG1388	LysM domain
CWQ21_RS09695	COG4589	Belongs to the CDS family
CWQ21_RS09700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWQ21_RS09705	COG1862	Preprotein translocase
CWQ21_RS09725	COG3493	citrate carrier protein
CWQ21_RS09730	COG3290	protein histidine kinase activity
CWQ21_RS09735	COG4565	transcriptional regulatory protein
CWQ21_RS09740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWQ21_RS09750	COG3842	ATPase activity
CWQ21_RS09835	COG0737	Belongs to the 5'-nucleotidase family
CWQ21_RS09845	COG1363	Peptidase, m42
CWQ21_RS09860	COG4753	response regulator
CWQ21_RS09860	COG2207	Transcriptional regulator
CWQ21_RS09865	COG2972	Histidine kinase
CWQ21_RS09870	COG3716	PTS system mannose fructose sorbose family IID component
CWQ21_RS09875	COG3715	PTS system
CWQ21_RS09910	COG1131	(ABC) transporter
CWQ21_RS09920	COG2274	protein secretion by the type I secretion system
CWQ21_RS09925	COG3290	protein histidine kinase activity
CWQ21_RS09945	COG2190	(PTS) system
CWQ21_RS09945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWQ21_RS09945	COG1263	PTS System
CWQ21_RS09950	COG5002	protein histidine kinase activity
CWQ21_RS09955	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS09965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWQ21_RS09970	COG0581	inorganic phosphate transmembrane transporter activity
CWQ21_RS09975	COG0573	inorganic phosphate transmembrane transporter activity
CWQ21_RS09990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWQ21_RS10005	COG0789	Transcriptional regulator
CWQ21_RS10015	COG0494	nUDIX hydrolase
CWQ21_RS10030	COG0456	acetyltransferase
CWQ21_RS10035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWQ21_RS10065	COG0582	viral genome integration into host DNA
CWQ21_RS10075	COG2946	Replication initiation factor
CWQ21_RS10100	COG2378	regulation of single-species biofilm formation
CWQ21_RS10105	COG0693	protein deglycase activity
CWQ21_RS10190	COG1131	(ABC) transporter
CWQ21_RS10230	COG1131	(ABC) transporter
CWQ21_RS10240	COG1396	sequence-specific DNA binding
CWQ21_RS10250	COG1694	Mazg nucleotide pyrophosphohydrolase
CWQ21_RS10255	COG1611	Belongs to the LOG family
CWQ21_RS10265	COG2897	thiosulfate sulfurtransferase activity
CWQ21_RS10285	COG0371	Dehydrogenase
CWQ21_RS10295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CWQ21_RS10295	COG0646	methionine synthase
CWQ21_RS10310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CWQ21_RS10330	COG2205	protein histidine kinase activity
CWQ21_RS10330	COG2770	Histidine kinase
CWQ21_RS10345	COG2814	Major facilitator Superfamily
CWQ21_RS10390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWQ21_RS10395	COG0564	pseudouridine synthase activity
CWQ21_RS10415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWQ21_RS10420	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CWQ21_RS10440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWQ21_RS10445	COG1116	anion transmembrane transporter activity
CWQ21_RS10445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWQ21_RS10455	COG0561	phosphatase activity
CWQ21_RS10460	COG2514	catechol 2,3-dioxygenase activity
CWQ21_RS10470	COG0602	queuosine metabolic process
CWQ21_RS10490	COG1328	CTP reductase activity
CWQ21_RS10510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CWQ21_RS10520	COG1393	Belongs to the ArsC family
CWQ21_RS10525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWQ21_RS10535	COG2818	Glycosylase
CWQ21_RS10585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWQ21_RS10590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWQ21_RS10610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWQ21_RS10665	COG0582	viral genome integration into host DNA
CWQ21_RS10740	COG0745	RESPONSE REGULATOR receiver
CWQ21_RS10745	COG5002	protein histidine kinase activity
CWQ21_RS10750	COG1288	antiporter activity
CWQ21_RS10760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWQ21_RS10765	COG3852	Histidine kinase
CWQ21_RS10770	COG0784	Response regulator, receiver
CWQ21_RS10775	COG0517	IMP dehydrogenase activity
CWQ21_RS10775	COG1125	glycine betaine transport
CWQ21_RS10780	COG1174	glycine betaine transport
CWQ21_RS10785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CWQ21_RS10785	COG0392	lysyltransferase activity
CWQ21_RS10795	COG3759	membrane
CWQ21_RS10905	COG2314	TM2 domain
CWQ21_RS10925	COG0582	viral genome integration into host DNA
CWQ21_RS10940	COG0305	Participates in initiation and elongation during chromosome replication
CWQ21_RS10960	COG2095	MarC family integral membrane protein
CWQ21_RS10965	COG0482	sulfurtransferase activity
CWQ21_RS10970	COG1760	l-serine dehydratase
CWQ21_RS10975	COG1760	l-serine dehydratase
CWQ21_RS10980	COG0741	lytic transglycosylase activity
CWQ21_RS11005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWQ21_RS11010	COG0612	Peptidase, M16
CWQ21_RS11015	COG0612	Peptidase, M16
CWQ21_RS11020	COG2501	S4 domain
CWQ21_RS11040	COG0516	GMP reductase activity
CWQ21_RS11040	COG0517	IMP dehydrogenase activity
CWQ21_RS11050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWQ21_RS11065	COG0454	-acetyltransferase
CWQ21_RS11080	COG0549	Belongs to the carbamate kinase family
CWQ21_RS11095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWQ21_RS11100	COG0488	(ABC) transporter
CWQ21_RS11105	COG4485	Bacterial membrane protein, YfhO
CWQ21_RS11125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CWQ21_RS11130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWQ21_RS11135	COG1475	DNA binding
CWQ21_RS11145	COG0592	DNA-directed DNA polymerase activity
CWQ21_RS11150	COG1597	lipid kinase activity
CWQ21_RS11165	COG0012	GTP binding
CWQ21_RS11175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWQ21_RS11185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWQ21_RS11215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins