locus-tag	class	description
EXA24_RS00195	COG0436	Aminotransferase
EXA24_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXA24_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXA24_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXA24_RS00275	COG1175	transmembrane transport
EXA24_RS00280	COG0395	ABC-type sugar transport system, permease component
EXA24_RS00295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXA24_RS00305	COG3458	cephalosporin-C deacetylase activity
EXA24_RS00320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXA24_RS00335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXA24_RS00350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXA24_RS00360	COG2755	lipolytic protein G-D-S-L family
EXA24_RS00360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXA24_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
EXA24_RS00365	COG1454	alcohol dehydrogenase
EXA24_RS00370	COG1064	alcohol dehydrogenase
EXA24_RS00380	COG0534	Mate efflux family protein
EXA24_RS00490	COG0201	protein transport
EXA24_RS00510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXA24_RS00520	COG0202	RNA polymerase activity
EXA24_RS00660	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXA24_RS00675	COG0443	Heat shock 70 kDa protein
EXA24_RS00685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXA24_RS00695	COG0351	phosphomethylpyrimidine kinase
EXA24_RS00700	COG4720	Psort location CytoplasmicMembrane, score
EXA24_RS00710	COG0668	transmembrane transport
EXA24_RS00740	COG0756	dUTP diphosphatase activity
EXA24_RS00755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXA24_RS00770	COG1879	ABC-type sugar transport system periplasmic component
EXA24_RS00775	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXA24_RS00790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXA24_RS00795	COG1609	Transcriptional regulator
EXA24_RS00800	COG0577	efflux transmembrane transporter activity
EXA24_RS00805	COG1136	(ABC) transporter
EXA24_RS00810	COG0745	RESPONSE REGULATOR receiver
EXA24_RS00815	COG5002	protein histidine kinase activity
EXA24_RS00830	COG0191	fructose-bisphosphate aldolase activity
EXA24_RS00850	COG1461	Dihydroxyacetone kinase
EXA24_RS00880	COG1755	Isoprenylcysteine carboxyl methyltransferase
EXA24_RS00885	COG5002	protein histidine kinase activity
EXA24_RS00890	COG0745	RESPONSE REGULATOR receiver
EXA24_RS00905	COG1126	abc transporter atp-binding protein
EXA24_RS00910	COG0765	amino acid transport
EXA24_RS00930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXA24_RS00940	COG0719	Fe-S assembly protein
EXA24_RS00945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXA24_RS00955	COG0719	Fe-S assembly protein
EXA24_RS00960	COG1686	Belongs to the peptidase S11 family
EXA24_RS00965	COG1686	Belongs to the peptidase S11 family
EXA24_RS00970	COG4166	transmembrane transport
EXA24_RS00975	COG0601	transmembrane transport
EXA24_RS00980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXA24_RS00985	COG0444	Belongs to the ABC transporter superfamily
EXA24_RS00990	COG4608	Belongs to the ABC transporter superfamily
EXA24_RS01030	COG1121	(ABC) transporter
EXA24_RS01035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXA24_RS01050	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXA24_RS01050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXA24_RS01070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXA24_RS01075	COG1459	type II secretion system
EXA24_RS01130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXA24_RS01135	COG1363	Peptidase, m42
EXA24_RS01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXA24_RS01155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXA24_RS01170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXA24_RS01190	COG1346	cytolysis
EXA24_RS01200	COG0601	transmembrane transport
EXA24_RS01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXA24_RS01210	COG1122	ATPase activity
EXA24_RS01220	COG1263	PTS System
EXA24_RS01220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXA24_RS01225	COG0366	Alpha amylase catalytic
EXA24_RS01230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXA24_RS01245	COG3959	Transketolase, thiamine diphosphate binding domain
EXA24_RS01250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXA24_RS01255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EXA24_RS01275	COG1045	serine acetyltransferase
EXA24_RS01290	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EXA24_RS01310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXA24_RS01320	COG4974	Belongs to the 'phage' integrase family
EXA24_RS01410	COG1396	sequence-specific DNA binding
EXA24_RS01415	COG2814	Major facilitator Superfamily
EXA24_RS01425	COG1732	Glycine betaine
EXA24_RS01525	COG0582	viral genome integration into host DNA
EXA24_RS01550	COG1395	domain, Protein
EXA24_RS01615	COG0519	Catalyzes the synthesis of GMP from XMP
EXA24_RS01660	COG1695	Transcriptional regulator
EXA24_RS01675	COG1755	Isoprenylcysteine carboxyl methyltransferase
EXA24_RS01715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXA24_RS01720	COG0446	pyridine nucleotide-disulphide oxidoreductase
EXA24_RS01740	COG1131	(ABC) transporter
EXA24_RS01750	COG1263	PTS System
EXA24_RS01750	COG2190	(PTS) system
EXA24_RS01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXA24_RS01755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXA24_RS01775	COG0768	penicillin binding
EXA24_RS01785	COG0513	Belongs to the DEAD box helicase family
EXA24_RS01800	COG1126	abc transporter atp-binding protein
EXA24_RS01810	COG0492	ferredoxin-NADP+ reductase activity
EXA24_RS01815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXA24_RS01825	COG3579	cysteine-type endopeptidase activity
EXA24_RS01830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXA24_RS01855	COG0116	Belongs to the methyltransferase superfamily
EXA24_RS01865	COG1854	S-ribosylhomocysteine lyase activity
EXA24_RS01870	COG1418	mRNA catabolic process
EXA24_RS01870	COG4372	Transposase
EXA24_RS01875	COG1131	(ABC) transporter
EXA24_RS01885	COG4585	Histidine kinase
EXA24_RS01890	COG2197	response regulator
EXA24_RS01900	COG0194	GDP metabolic process
EXA24_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXA24_RS01915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXA24_RS01920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXA24_RS01920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXA24_RS01930	COG2815	serine threonine protein kinase
EXA24_RS01930	COG0515	serine threonine protein kinase
EXA24_RS01940	COG4585	Histidine kinase
EXA24_RS01945	COG2197	response regulator
EXA24_RS01955	COG1098	S1 RNA binding domain
EXA24_RS01960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXA24_RS01965	COG1349	DNA-binding transcription factor activity
EXA24_RS01975	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXA24_RS01985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXA24_RS01990	COG1882	Formate acetyltransferase
EXA24_RS02010	COG1739	Uncharacterized protein family UPF0029
EXA24_RS02015	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXA24_RS02020	COG1040	competence protein
EXA24_RS02055	COG0527	aspartate kinase activity
EXA24_RS02060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXA24_RS02065	COG1024	Enoyl-CoA hydratase
EXA24_RS02075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXA24_RS02085	COG2070	2-Nitropropane dioxygenase
EXA24_RS02090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXA24_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
EXA24_RS02100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXA24_RS02115	COG0439	Biotin carboxylase
EXA24_RS02135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EXA24_RS02150	COG3716	PTS system mannose fructose sorbose family IID component
EXA24_RS02155	COG3715	PTS system
EXA24_RS02165	COG0561	phosphatase activity
EXA24_RS02180	COG2252	PERMEase
EXA24_RS02185	COG0802	atpase or kinase
EXA24_RS02195	COG1316	TRANSCRIPTIONal
EXA24_RS02205	COG0537	adenosine 5'-monophosphoramidase activity
EXA24_RS02220	COG1131	(ABC) transporter
EXA24_RS02225	COG4473	ABC transporter
EXA24_RS02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXA24_RS02250	COG0195	Participates in both transcription termination and antitermination
EXA24_RS02255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXA24_RS02265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXA24_RS02270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXA24_RS02295	COG2860	membrane
EXA24_RS02305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXA24_RS02305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXA24_RS02310	COG1832	CoA-binding protein
EXA24_RS02330	COG5002	protein histidine kinase activity
EXA24_RS02350	COG1268	BioY protein
EXA24_RS02355	COG1234	tRNA 3'-trailer cleavage
EXA24_RS02370	COG0166	Belongs to the GPI family
EXA24_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXA24_RS02380	COG0457	Tetratricopeptide repeat
EXA24_RS02380	COG0705	Rhomboid family
EXA24_RS02385	COG1744	ABC transporter substrate-binding protein PnrA-like
EXA24_RS02390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXA24_RS02405	COG0706	membrane insertase activity
EXA24_RS02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXA24_RS02475	COG2153	protein acetylation
EXA24_RS02485	COG1216	Glycosyl transferase, family 2
EXA24_RS02485	COG1442	glycosyl transferase family 8
EXA24_RS02530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXA24_RS02540	COG0789	Transcriptional regulator
EXA24_RS02550	COG0656	L-ascorbic acid biosynthetic process
EXA24_RS02595	COG2226	methyltransferase
EXA24_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXA24_RS02610	COG3414	Phosphotransferase system galactitol-specific IIB component
EXA24_RS02615	COG3775	system Galactitol-specific IIC component
EXA24_RS02620	COG0235	Class ii aldolase
EXA24_RS02630	COG3775	system Galactitol-specific IIC component
EXA24_RS02635	COG3414	Phosphotransferase system galactitol-specific IIB component
EXA24_RS02640	COG2207	Transcriptional regulator
EXA24_RS02650	COG1175	transmembrane transport
EXA24_RS02655	COG0395	ABC-type sugar transport system, permease component
EXA24_RS02675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXA24_RS02680	COG2017	converts alpha-aldose to the beta-anomer
EXA24_RS02740	COG1518	maintenance of DNA repeat elements
EXA24_RS02745	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EXA24_RS02750	COG0673	inositol 2-dehydrogenase activity
EXA24_RS02760	COG2315	Protein conserved in bacteria
EXA24_RS02775	COG0742	ribosomal rna small subunit methyltransferase
EXA24_RS02790	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXA24_RS02795	COG0737	Belongs to the 5'-nucleotidase family
EXA24_RS02800	COG4470	Protein conserved in bacteria
EXA24_RS02815	COG1132	(ABC) transporter
EXA24_RS02820	COG1132	(ABC) transporter
EXA24_RS02825	COG0512	Glutamine amidotransferase of anthranilate synthase
EXA24_RS02830	COG1268	BioY protein
EXA24_RS02835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXA24_RS02855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXA24_RS02870	COG1940	carbohydrate kinase activity
EXA24_RS02875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXA24_RS02890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXA24_RS02915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXA24_RS02925	COG0762	integral membrane protein
EXA24_RS02930	COG2302	S4 RNA-binding domain
EXA24_RS02935	COG3599	regulation of cell shape
EXA24_RS02950	COG0494	nUDIX hydrolase
EXA24_RS02955	COG0542	response to heat
EXA24_RS02960	COG4703	Protein of unknown function (DUF1797)
EXA24_RS02965	COG0765	amino acid transport
EXA24_RS02970	COG1126	abc transporter atp-binding protein
EXA24_RS02975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXA24_RS02985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EXA24_RS02990	COG1570	exodeoxyribonuclease VII activity
EXA24_RS02995	COG1722	exodeoxyribonuclease VII activity
EXA24_RS03005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXA24_RS03010	COG1438	arginine binding
EXA24_RS03015	COG0497	DNA recombination
EXA24_RS03020	COG1307	EDD domain protein, DegV family
EXA24_RS03025	COG2755	lipolytic protein G-D-S-L family
EXA24_RS03070	COG1078	dGTPase activity
EXA24_RS03095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EXA24_RS03105	COG2884	Cell division ATP-binding protein ftsE
EXA24_RS03110	COG2177	Part of the ABC transporter FtsEX involved in
EXA24_RS03130	COG1199	ATP-dependent helicase activity
EXA24_RS03130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXA24_RS03135	COG0436	Aminotransferase
EXA24_RS03140	COG0017	Asparaginyl-tRNA synthetase
EXA24_RS03160	COG1660	Displays ATPase and GTPase activities
EXA24_RS03185	COG0254	rRNA binding
EXA24_RS03190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXA24_RS03195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EXA24_RS03200	COG0716	FMN binding
EXA24_RS03205	COG1605	Chorismate mutase
EXA24_RS03205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXA24_RS03210	COG0038	chloride channel
EXA24_RS03215	COG0335	large ribosomal subunit rRNA binding
EXA24_RS03260	COG1136	(ABC) transporter
EXA24_RS03275	COG5002	protein histidine kinase activity
EXA24_RS03295	COG0772	Belongs to the SEDS family
EXA24_RS03315	COG0560	Phosphoserine phosphatase
EXA24_RS03330	COG0148	phosphopyruvate hydratase activity
EXA24_RS03350	COG1316	TRANSCRIPTIONal
EXA24_RS03370	COG0270	DNA (cytosine-5-)-methyltransferase activity
EXA24_RS03505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXA24_RS03540	COG2226	methyltransferase
EXA24_RS03590	COG1192	Involved in chromosome partitioning
EXA24_RS03670	COG1396	sequence-specific DNA binding
EXA24_RS03675	COG0542	response to heat
EXA24_RS03680	COG0613	PHP domain protein
EXA24_RS03695	COG3843	relaxase mobilization nuclease domain protein
EXA24_RS03715	COG1131	(ABC) transporter
EXA24_RS03755	COG3700	Belongs to the class B bacterial acid phosphatase family
EXA24_RS03860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXA24_RS03865	COG4555	ABC transporter
EXA24_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
EXA24_RS03895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXA24_RS03900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXA24_RS03920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXA24_RS03925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXA24_RS03945	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EXA24_RS03945	COG3064	Membrane
EXA24_RS03960	COG3590	peptidase
EXA24_RS04015	COG1136	(ABC) transporter
EXA24_RS04030	COG0586	Pfam SNARE associated Golgi protein
EXA24_RS04035	COG4619	ABC transporter
EXA24_RS04040	COG0390	transport system, permease component
EXA24_RS04050	COG0583	DNA-binding transcription factor activity
EXA24_RS04065	COG2211	Major facilitator Superfamily
EXA24_RS04075	COG3250	beta-galactosidase activity
EXA24_RS04080	COG2186	Transcriptional regulator
EXA24_RS04085	COG0800	Aldolase
EXA24_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
EXA24_RS04120	COG1609	Transcriptional regulator
EXA24_RS04135	COG0438	transferase activity, transferring glycosyl groups
EXA24_RS04160	COG0765	amino acid transport
EXA24_RS04165	COG0765	amino acid transport
EXA24_RS04170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXA24_RS04175	COG1126	abc transporter atp-binding protein
EXA24_RS04180	COG0745	RESPONSE REGULATOR receiver
EXA24_RS04185	COG5002	protein histidine kinase activity
EXA24_RS04190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXA24_RS04195	COG2832	Protein of unknown function (DUF454)
EXA24_RS04205	COG1196	nuclear chromosome segregation
EXA24_RS04260	COG4372	Transposase
EXA24_RS04310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXA24_RS04310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXA24_RS04360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXA24_RS04380	COG0270	DNA (cytosine-5-)-methyltransferase activity
EXA24_RS04420	COG4695	Portal protein
EXA24_RS04425	COG0740	serine-type endopeptidase activity
EXA24_RS04490	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXA24_RS04490	COG1388	LysM domain
EXA24_RS04515	COG0561	phosphatase activity
EXA24_RS04520	COG0561	phosphatase activity
EXA24_RS04525	COG0552	protein localization to endoplasmic reticulum
EXA24_RS04530	COG3689	TIGRFAM TIGR03943 family protein
EXA24_RS04535	COG0701	Predicted permease
EXA24_RS04550	COG2183	response to ionizing radiation
EXA24_RS04555	COG3091	SprT-like family
EXA24_RS04560	COG1983	PspC domain protein
EXA24_RS04600	COG4443	Transcriptional Coactivator p15 (PC4)
EXA24_RS04610	COG1914	H( )-stimulated, divalent metal cation uptake system
EXA24_RS04625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXA24_RS04625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXA24_RS04650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXA24_RS04675	COG1164	Oligoendopeptidase f
EXA24_RS04685	COG0772	Belongs to the SEDS family
EXA24_RS04705	COG0768	penicillin binding
EXA24_RS04720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXA24_RS04725	COG2223	nitrite transmembrane transporter activity
EXA24_RS04750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXA24_RS04755	COG2011	ABC-type metal ion transport system permease component
EXA24_RS04760	COG1464	Belongs to the NlpA lipoprotein family
EXA24_RS04765	COG0513	Belongs to the DEAD box helicase family
EXA24_RS04775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXA24_RS04780	COG0204	Acyl-transferase
EXA24_RS04785	COG1596	polysaccharide export
EXA24_RS04785	COG1555	photosystem II stabilization
EXA24_RS04790	COG0658	competence protein
EXA24_RS04790	COG2333	competence protein COMEC
EXA24_RS04795	COG0561	phosphatase activity
EXA24_RS04800	COG1609	Transcriptional regulator
EXA24_RS04805	COG0657	acetylesterase activity
EXA24_RS04810	COG2226	methyltransferase
EXA24_RS04820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXA24_RS04830	COG2190	(PTS) system
EXA24_RS04830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXA24_RS04830	COG1263	PTS System
EXA24_RS04840	COG3835	regulator
EXA24_RS04845	COG1929	Belongs to the glycerate kinase type-1 family
EXA24_RS04850	COG2610	gluconate transmembrane transporter activity
EXA24_RS04860	COG1846	Transcriptional regulator
EXA24_RS04875	COG0363	glucosamine-6-phosphate deaminase activity
EXA24_RS04880	COG0435	Glutathione S-transferase
EXA24_RS04885	COG1187	pseudouridine synthase activity
EXA24_RS04905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXA24_RS04910	COG4122	O-methyltransferase activity
EXA24_RS04920	COG4894	glucomannan catabolic process
EXA24_RS04935	COG1442	glycosyl transferase family 8
EXA24_RS04945	COG1476	TRANSCRIPTIONal
EXA24_RS04960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXA24_RS04965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXA24_RS04970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EXA24_RS04985	COG1012	belongs to the aldehyde dehydrogenase family
EXA24_RS04990	COG0726	polysaccharide deacetylase
EXA24_RS05005	COG1956	GAF domain-containing protein
EXA24_RS05010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXA24_RS05020	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EXA24_RS05020	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EXA24_RS05050	COG4721	ABC-type cobalt transport system, permease component
EXA24_RS05055	COG1122	ATPase activity
EXA24_RS05065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXA24_RS05095	COG4109	DRTGG domain
EXA24_RS05100	COG0024	Methionine aminopeptidase
EXA24_RS05110	COG2246	polysaccharide biosynthetic process
EXA24_RS05115	COG4708	membrane
EXA24_RS05125	COG1597	lipid kinase activity
EXA24_RS05130	COG1523	belongs to the glycosyl hydrolase 13 family
EXA24_RS05145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXA24_RS05230	COG2321	neutral zinc metallopeptidase
EXA24_RS05255	COG0488	(ABC) transporter
EXA24_RS05260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXA24_RS05265	COG0022	dehydrogenase e1 component
EXA24_RS05265	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXA24_RS05270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXA24_RS05280	COG0095	Lipoate-protein ligase
EXA24_RS05285	COG3442	glutamine amidotransferase
EXA24_RS05290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXA24_RS05295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXA24_RS05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXA24_RS05330	COG0647	UMP catabolic process
EXA24_RS05340	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EXA24_RS05345	COG1518	maintenance of DNA repeat elements
EXA24_RS05350	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EXA24_RS05370	COG0481	GTPase activity
EXA24_RS05380	COG1418	mRNA catabolic process
EXA24_RS05385	COG0456	acetyltransferase
EXA24_RS05395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXA24_RS05425	COG1131	(ABC) transporter
EXA24_RS05430	COG1725	Transcriptional regulator
EXA24_RS05440	COG0205	6-phosphofructokinase activity
EXA24_RS05445	COG0469	pyruvate kinase activity
EXA24_RS05455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EXA24_RS05460	COG2824	Alkylphosphonate utilization operon protein PhnA
EXA24_RS05465	COG0765	amino acid transport
EXA24_RS05470	COG1126	abc transporter atp-binding protein
EXA24_RS05485	COG1072	(Pantothenic acid kinase))
EXA24_RS05490	COG2813	Specifically methylates the guanine in position
EXA24_RS05500	COG1744	ABC transporter substrate-binding protein PnrA-like
EXA24_RS05535	COG3764	Sortase (surface protein transpeptidase)
EXA24_RS05540	COG0346	lactoylglutathione lyase activity
EXA24_RS05565	COG2188	Transcriptional regulator
EXA24_RS05580	COG1464	Belongs to the NlpA lipoprotein family
EXA24_RS05595	COG1136	(ABC) transporter
EXA24_RS05605	COG0745	RESPONSE REGULATOR receiver
EXA24_RS05610	COG5002	protein histidine kinase activity
EXA24_RS05615	COG4974	Belongs to the 'phage' integrase family
EXA24_RS05620	COG4166	transmembrane transport
EXA24_RS05635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXA24_RS05640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXA24_RS05645	COG5002	protein histidine kinase activity
EXA24_RS05650	COG0745	RESPONSE REGULATOR receiver
EXA24_RS05660	COG0704	Plays a role in the regulation of phosphate uptake
EXA24_RS05665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXA24_RS05670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXA24_RS05675	COG0581	inorganic phosphate transmembrane transporter activity
EXA24_RS05680	COG0573	inorganic phosphate transmembrane transporter activity
EXA24_RS05690	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EXA24_RS05690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXA24_RS05695	COG0483	inositol monophosphate 1-phosphatase activity
EXA24_RS05710	COG0196	riboflavin kinase activity
EXA24_RS05715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EXA24_RS05745	COG1136	(ABC) transporter
EXA24_RS05750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXA24_RS05755	COG0758	DNA mediated transformation
EXA24_RS05760	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXA24_RS05765	COG4604	ABC transporter, ATP-binding protein
EXA24_RS05770	COG4605	iron ion homeostasis
EXA24_RS05775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXA24_RS05780	COG0110	maltose O-acetyltransferase activity
EXA24_RS05790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXA24_RS05795	COG1376	ErfK ybiS ycfS ynhG family protein
EXA24_RS05800	COG1966	Carbon starvation protein
EXA24_RS05805	COG3279	Response regulator of the LytR AlgR family
EXA24_RS05810	COG3275	phosphorelay sensor kinase activity
EXA24_RS05905	COG0505	Belongs to the CarA family
EXA24_RS05915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXA24_RS05935	COG0488	(ABC) transporter
EXA24_RS05945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXA24_RS05955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXA24_RS05995	COG0095	Lipoate-protein ligase
EXA24_RS06005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXA24_RS06010	COG4684	Psort location CytoplasmicMembrane, score
EXA24_RS06015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXA24_RS06025	COG1132	(ABC) transporter
EXA24_RS06055	COG2890	protein-(glutamine-N5) methyltransferase activity
EXA24_RS06070	COG1942	4-Oxalocrotonate Tautomerase
EXA24_RS06085	COG0431	NADPH-dependent FMN reductase
EXA24_RS06085	COG1053	succinate dehydrogenase
EXA24_RS06085	COG3976	FMN-binding domain protein
EXA24_RS06095	COG2233	PERMEase
EXA24_RS06110	COG0477	Major facilitator Superfamily
EXA24_RS06125	COG4221	oxidoreductase activity
EXA24_RS06130	COG0280	phosphate acetyltransferase
EXA24_RS06135	COG0564	pseudouridine synthase activity
EXA24_RS06140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EXA24_RS06145	COG2357	RelA SpoT domain protein
EXA24_RS06160	COG1104	cysteine desulfurase activity
EXA24_RS06170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXA24_RS06175	COG2003	Belongs to the UPF0758 family
EXA24_RS06180	COG0628	permease
EXA24_RS06185	COG2723	6-phospho-beta-galactosidase activity
EXA24_RS06195	COG0561	phosphatase activity
EXA24_RS06205	COG0038	chloride channel
EXA24_RS06215	COG1177	transmembrane transport
EXA24_RS06220	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXA24_RS06230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EXA24_RS06235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXA24_RS06255	COG0285	dihydrofolate synthase activity
EXA24_RS06260	COG2962	Rard protein
EXA24_RS06275	COG0726	polysaccharide deacetylase
EXA24_RS06280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXA24_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
EXA24_RS06360	COG2261	transglycosylase associated protein
EXA24_RS06385	COG1115	amino acid carrier protein
EXA24_RS06390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXA24_RS06400	COG1346	cytolysis
EXA24_RS06430	COG4974	Belongs to the 'phage' integrase family
EXA24_RS06440	COG0539	negative regulation of cytoplasmic translation
EXA24_RS06460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXA24_RS06470	COG0187	DNA topoisomerase II activity
EXA24_RS06475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXA24_RS06480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXA24_RS06490	COG2755	lipolytic protein G-D-S-L family
EXA24_RS06490	COG1083	cytidylyl-transferase
EXA24_RS06505	COG2089	acid synthase
EXA24_RS06525	COG1216	Glycosyl transferase, family 2
EXA24_RS06525	COG1442	glycosyl transferase family 8
EXA24_RS06540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXA24_RS06570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EXA24_RS06620	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EXA24_RS06625	COG3527	Alpha-acetolactate decarboxylase
EXA24_RS06630	COG0028	Belongs to the TPP enzyme family
EXA24_RS06635	COG0457	Tetratricopeptide repeat
EXA24_RS06640	COG0628	permease
EXA24_RS06650	COG1051	belongs to the nudix hydrolase family
EXA24_RS06655	COG5492	domain, Protein
EXA24_RS06660	COG1088	dTDP-glucose 4,6-dehydratase activity
EXA24_RS06670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXA24_RS06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXA24_RS06685	COG2384	SAM-dependent methyltransferase
EXA24_RS06705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXA24_RS06705	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXA24_RS06710	COG0300	oxidoreductase activity
EXA24_RS06745	COG1523	belongs to the glycosyl hydrolase 13 family
EXA24_RS06755	COG1573	uracil-dna glycosylase
EXA24_RS06760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXA24_RS06785	COG0534	Mate efflux family protein
EXA24_RS06825	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXA24_RS06845	COG2176	DNA-directed DNA polymerase activity
EXA24_RS06875	COG2040	homocysteine
EXA24_RS06880	COG0833	amino acid
EXA24_RS06910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXA24_RS06920	COG3425	synthase
EXA24_RS06935	COG1272	protein, Hemolysin III
EXA24_RS06980	COG0745	RESPONSE REGULATOR receiver
EXA24_RS06985	COG2357	RelA SpoT domain protein
EXA24_RS06990	COG1132	(ABC) transporter
EXA24_RS07005	COG0737	Belongs to the 5'-nucleotidase family
EXA24_RS07010	COG0242	peptide deformylase activity
EXA24_RS07015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXA24_RS07025	COG1132	(ABC) transporter
EXA24_RS07040	COG0488	(ABC) transporter
EXA24_RS07075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXA24_RS07075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXA24_RS07075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXA24_RS07080	COG1105	Belongs to the carbohydrate kinase PfkB family
EXA24_RS07085	COG1349	DNA-binding transcription factor activity
EXA24_RS07090	COG1388	LysM domain
EXA24_RS07090	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXA24_RS07140	COG1837	Belongs to the UPF0109 family
EXA24_RS07145	COG0228	four-way junction DNA binding
EXA24_RS07150	COG0577	efflux transmembrane transporter activity
EXA24_RS07155	COG1136	(ABC) transporter
EXA24_RS07160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EXA24_RS07170	COG0505	Belongs to the CarA family
EXA24_RS07180	COG0564	pseudouridine synthase activity
EXA24_RS07190	COG0583	DNA-binding transcription factor activity
EXA24_RS07195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EXA24_RS07220	COG1104	cysteine desulfurase activity
EXA24_RS07230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXA24_RS07255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXA24_RS07260	COG1368	sulfuric ester hydrolase activity
EXA24_RS07265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXA24_RS07275	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EXA24_RS07305	COG2244	polysaccharide biosynthetic process
EXA24_RS07315	COG1120	ATPase activity
EXA24_RS07320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXA24_RS07325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXA24_RS07330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXA24_RS07345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXA24_RS07350	COG1253	flavin adenine dinucleotide binding
EXA24_RS07355	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXA24_RS07360	COG1242	4 iron, 4 sulfur cluster binding
EXA24_RS07365	COG0671	phosphoesterase, PA-phosphatase related
EXA24_RS07370	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXA24_RS07405	COG0297	glycogen (starch) synthase activity
EXA24_RS07445	COG3475	LICD family
EXA24_RS07460	COG0463	Glycosyl transferase, family 2
EXA24_RS07465	COG1215	transferase activity, transferring glycosyl groups
EXA24_RS07475	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXA24_RS07480	COG2151	metal-sulfur cluster biosynthetic enzyme
EXA24_RS07485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXA24_RS07490	COG0358	DNA primase activity
EXA24_RS07495	COG1970	mechanosensitive ion channel activity
EXA24_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXA24_RS07520	COG0004	ammonium transporteR
EXA24_RS07540	COG2271	Major facilitator Superfamily
EXA24_RS07545	COG0058	SHG alpha-glucan phosphorylase activity
EXA24_RS07550	COG1640	4-alpha-glucanotransferase
EXA24_RS07555	COG1609	Transcriptional regulator
EXA24_RS07565	COG1175	transmembrane transport
EXA24_RS07570	COG3833	ABC-type maltose transport systems, permease component
EXA24_RS07575	COG3104	oligopeptide transport
EXA24_RS07605	COG0765	amino acid transport
EXA24_RS07610	COG1126	abc transporter atp-binding protein
EXA24_RS07635	COG2309	aminopeptidase activity
EXA24_RS07655	COG1187	pseudouridine synthase activity
EXA24_RS07660	COG0656	L-ascorbic acid biosynthetic process
EXA24_RS07665	COG0778	Nitroreductase
EXA24_RS07670	COG0346	lactoylglutathione lyase activity
EXA24_RS07675	COG0463	Glycosyl transferase, family 2
EXA24_RS07680	COG1113	amino acid transport
EXA24_RS07685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXA24_RS07690	COG0557	exoribonuclease II activity
EXA24_RS07705	COG2814	Major facilitator Superfamily
EXA24_RS07715	COG1131	(ABC) transporter
EXA24_RS07725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EXA24_RS07730	COG1396	sequence-specific DNA binding
EXA24_RS07780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXA24_RS07785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXA24_RS07805	COG1702	phosphate starvation-inducible protein PhoH
EXA24_RS07830	COG0233	cytoplasmic translational termination
EXA24_RS07845	COG0444	Belongs to the ABC transporter superfamily
EXA24_RS07850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXA24_RS07855	COG0601	transmembrane transport
EXA24_RS07860	COG0747	negative chemotaxis
EXA24_RS07865	COG0081	regulation of translation
EXA24_RS07885	COG1473	amidohydrolase
EXA24_RS07890	COG0583	DNA-binding transcription factor activity
EXA24_RS07905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXA24_RS07910	COG1674	ftsk spoiiie
EXA24_RS07915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXA24_RS07940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXA24_RS07970	COG0673	inositol 2-dehydrogenase activity
EXA24_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
EXA24_RS08035	COG1114	Component of the transport system for branched-chain amino acids
EXA24_RS08040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXA24_RS08040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXA24_RS08055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXA24_RS08065	COG0708	Exodeoxyribonuclease III
EXA24_RS08070	COG1393	Belongs to the ArsC family
EXA24_RS08075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXA24_RS08090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EXA24_RS08110	COG0470	DNA polymerase III
EXA24_RS08125	COG0517	IMP dehydrogenase activity
EXA24_RS08145	COG0559	Belongs to the binding-protein-dependent transport system permease family
EXA24_RS08165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EXA24_RS08170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXA24_RS08180	COG0531	amino acid
EXA24_RS08185	COG0569	domain protein
EXA24_RS08190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXA24_RS08200	COG1187	pseudouridine synthase activity
EXA24_RS08250	COG1827	regulation of RNA biosynthetic process
EXA24_RS08265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXA24_RS08270	COG1254	Belongs to the acylphosphatase family
EXA24_RS08280	COG0765	amino acid transport
EXA24_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXA24_RS08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXA24_RS08330	COG1484	DNA-dependent DNA replication
EXA24_RS08345	COG5002	protein histidine kinase activity
EXA24_RS08350	COG0745	RESPONSE REGULATOR receiver
EXA24_RS08365	COG1704	LemA family
EXA24_RS08370	COG0357	Ribosomal RNA small subunit methyltransferase G
EXA24_RS08375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXA24_RS08380	COG0569	domain protein
EXA24_RS08405	COG1114	Component of the transport system for branched-chain amino acids
EXA24_RS08410	COG1063	alcohol dehydrogenase
EXA24_RS08435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXA24_RS08440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EXA24_RS08445	COG0217	transcriptional regulatory protein
EXA24_RS08475	COG2376	Dihydroxyacetone kinase
EXA24_RS08480	COG1309	transcriptional regulator
EXA24_RS08485	COG2376	Dihydroxyacetone kinase
EXA24_RS08490	COG1461	Dihydroxyacetone kinase
EXA24_RS08495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EXA24_RS08500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXA24_RS08510	COG0789	Transcriptional regulator
EXA24_RS08525	COG2226	methyltransferase
EXA24_RS08530	COG0799	negative regulation of ribosome biogenesis
EXA24_RS08540	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXA24_RS08545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXA24_RS08550	COG1534	Rna-binding protein
EXA24_RS08555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXA24_RS08560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXA24_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EXA24_RS08585	COG0574	Belongs to the PEP-utilizing enzyme family
EXA24_RS08595	COG0517	IMP dehydrogenase activity
EXA24_RS08605	COG1335	isochorismatase
EXA24_RS08610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXA24_RS08615	COG0436	Aminotransferase
EXA24_RS08620	COG0589	response to stress
EXA24_RS08625	COG0561	phosphatase activity
EXA24_RS08630	COG0252	asparaginase activity
EXA24_RS08640	COG4989	oxidoreductase activity
EXA24_RS08645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXA24_RS08650	COG3942	CHAP domain
EXA24_RS08650	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXA24_RS08660	COG0736	holo-[acyl-carrier-protein] synthase activity
EXA24_RS08665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EXA24_RS08675	COG1482	cell wall glycoprotein biosynthetic process
EXA24_RS08680	COG1940	carbohydrate kinase activity
EXA24_RS08685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXA24_RS08685	COG1263	PTS System
EXA24_RS08685	COG2190	(PTS) system
EXA24_RS08690	COG1621	beta-fructofuranosidase activity
EXA24_RS08695	COG1609	Transcriptional regulator
EXA24_RS08700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXA24_RS08710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXA24_RS08745	COG2131	deaminase
EXA24_RS08760	COG2814	Major facilitator Superfamily
EXA24_RS08785	COG0629	single-stranded DNA binding
EXA24_RS08790	COG0360	Binds together with S18 to 16S ribosomal RNA
EXA24_RS08795	COG1194	a g-specific adenine glycosylase
EXA24_RS08805	COG3118	belongs to the thioredoxin family
EXA24_RS08835	COG0681	Belongs to the peptidase S26 family
EXA24_RS08840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXA24_RS08855	COG1882	Formate acetyltransferase
EXA24_RS08860	COG3576	pyridoxamine 5-phosphate
EXA24_RS08865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXA24_RS08880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXA24_RS08890	COG2814	Major facilitator Superfamily
EXA24_RS08895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXA24_RS08910	COG0142	geranyltranstransferase activity
EXA24_RS08915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXA24_RS08920	COG4988	ABC transporter
EXA24_RS08925	COG1294	oxidase, subunit
EXA24_RS08930	COG1271	oxidase subunit
EXA24_RS08935	COG1252	NADH dehydrogenase
EXA24_RS08975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXA24_RS08980	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EXA24_RS08980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXA24_RS08980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXA24_RS08985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXA24_RS08990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXA24_RS08995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXA24_RS08995	COG3711	transcriptional antiterminator
EXA24_RS09015	COG4221	oxidoreductase activity
EXA24_RS09030	COG0656	L-ascorbic acid biosynthetic process
EXA24_RS09050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXA24_RS09055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EXA24_RS09060	COG0789	Transcriptional regulator
EXA24_RS09075	COG2081	HI0933 family
EXA24_RS09110	COG0456	acetyltransferase
EXA24_RS09115	COG1214	PFAM Peptidase M22, glycoprotease
EXA24_RS09130	COG3942	CHAP domain
EXA24_RS09135	COG0174	glutamine synthetase
EXA24_RS09140	COG0789	Transcriptional regulator
EXA24_RS09155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXA24_RS09180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXA24_RS09205	COG1162	GTPase activity
EXA24_RS09230	COG0084	hydrolase, TatD family'
EXA24_RS09255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXA24_RS09260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXA24_RS09265	COG1696	Membrane protein involved in D-alanine export
EXA24_RS09285	COG0745	RESPONSE REGULATOR receiver
EXA24_RS09305	COG3448	diguanylate cyclase activity
EXA24_RS09305	COG4175	Glycine betaine
EXA24_RS09310	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EXA24_RS09330	COG1070	Carbohydrate kinase
EXA24_RS09340	COG3775	system Galactitol-specific IIC component
EXA24_RS09345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXA24_RS09355	COG1609	Transcriptional regulator
EXA24_RS09440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXA24_RS09445	COG1428	Deoxynucleoside kinase
EXA24_RS09455	COG0542	response to heat
EXA24_RS09460	COG4463	regulation of RNA biosynthetic process
EXA24_RS09470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXA24_RS09480	COG0450	alkyl hydroperoxide reductase
EXA24_RS09610	COG0582	viral genome integration into host DNA
EXA24_RS09630	COG3344	reverse transcriptase
EXA24_RS09680	COG0305	Participates in initiation and elongation during chromosome replication
EXA24_RS09715	COG1396	sequence-specific DNA binding
EXA24_RS09730	COG4974	Belongs to the 'phage' integrase family
EXA24_RS09735	COG0025	NhaP-type Na H and K H
EXA24_RS09745	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXA24_RS09750	COG3590	peptidase
EXA24_RS09775	COG1609	Transcriptional regulator
EXA24_RS09800	COG2176	DNA-directed DNA polymerase activity
EXA24_RS09805	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXA24_RS09805	COG1388	LysM domain
EXA24_RS09820	COG4589	Belongs to the CDS family
EXA24_RS09825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EXA24_RS09830	COG1862	Preprotein translocase
EXA24_RS09845	COG3493	citrate carrier protein
EXA24_RS09850	COG3290	protein histidine kinase activity
EXA24_RS09855	COG4565	transcriptional regulatory protein
EXA24_RS09860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXA24_RS09870	COG3842	ATPase activity
EXA24_RS09950	COG0737	Belongs to the 5'-nucleotidase family
EXA24_RS09960	COG1363	Peptidase, m42
EXA24_RS09980	COG2972	Histidine kinase
EXA24_RS09985	COG3716	PTS system mannose fructose sorbose family IID component
EXA24_RS09990	COG3715	PTS system
EXA24_RS10025	COG1131	(ABC) transporter
EXA24_RS10035	COG2274	protein secretion by the type I secretion system
EXA24_RS10040	COG3290	protein histidine kinase activity
EXA24_RS10055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXA24_RS10055	COG1263	PTS System
EXA24_RS10055	COG2190	(PTS) system
EXA24_RS10060	COG5002	protein histidine kinase activity
EXA24_RS10065	COG0745	RESPONSE REGULATOR receiver
EXA24_RS10080	COG0581	inorganic phosphate transmembrane transporter activity
EXA24_RS10085	COG0573	inorganic phosphate transmembrane transporter activity
EXA24_RS10100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXA24_RS10115	COG0789	Transcriptional regulator
EXA24_RS10125	COG0494	nUDIX hydrolase
EXA24_RS10140	COG0456	acetyltransferase
EXA24_RS10145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXA24_RS10170	COG0582	viral genome integration into host DNA
EXA24_RS10180	COG2946	Replication initiation factor
EXA24_RS10200	COG2378	regulation of single-species biofilm formation
EXA24_RS10205	COG0693	protein deglycase activity
EXA24_RS10280	COG1131	(ABC) transporter
EXA24_RS10325	COG1131	(ABC) transporter
EXA24_RS10335	COG1396	sequence-specific DNA binding
EXA24_RS10345	COG1694	Mazg nucleotide pyrophosphohydrolase
EXA24_RS10350	COG1611	Belongs to the LOG family
EXA24_RS10360	COG2897	thiosulfate sulfurtransferase activity
EXA24_RS10375	COG0371	Dehydrogenase
EXA24_RS10385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXA24_RS10385	COG0646	methionine synthase
EXA24_RS10410	COG0745	RESPONSE REGULATOR receiver
EXA24_RS10415	COG2770	Histidine kinase
EXA24_RS10415	COG2205	protein histidine kinase activity
EXA24_RS10430	COG2814	Major facilitator Superfamily
EXA24_RS10435	COG4667	esterase of the alpha-beta hydrolase superfamily
EXA24_RS10460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXA24_RS10465	COG0564	pseudouridine synthase activity
EXA24_RS10485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXA24_RS10490	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EXA24_RS10510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXA24_RS10515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXA24_RS10515	COG1116	anion transmembrane transporter activity
EXA24_RS10525	COG0561	phosphatase activity
EXA24_RS10530	COG2514	catechol 2,3-dioxygenase activity
EXA24_RS10540	COG0602	queuosine metabolic process
EXA24_RS10560	COG1328	CTP reductase activity
EXA24_RS10575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXA24_RS10585	COG1393	Belongs to the ArsC family
EXA24_RS10590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXA24_RS10600	COG2818	Glycosylase
EXA24_RS10645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXA24_RS10650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXA24_RS10670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXA24_RS10725	COG4974	Belongs to the 'phage' integrase family
EXA24_RS10735	COG0745	RESPONSE REGULATOR receiver
EXA24_RS10740	COG5002	protein histidine kinase activity
EXA24_RS10745	COG1288	antiporter activity
EXA24_RS10755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EXA24_RS10760	COG3852	Histidine kinase
EXA24_RS10765	COG0784	Response regulator, receiver
EXA24_RS10770	COG1125	glycine betaine transport
EXA24_RS10770	COG0517	IMP dehydrogenase activity
EXA24_RS10775	COG1174	glycine betaine transport
EXA24_RS10780	COG0392	lysyltransferase activity
EXA24_RS10780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXA24_RS10790	COG3759	membrane
EXA24_RS10900	COG2314	TM2 domain
EXA24_RS10920	COG0582	viral genome integration into host DNA
EXA24_RS10935	COG0305	Participates in initiation and elongation during chromosome replication
EXA24_RS10955	COG2095	MarC family integral membrane protein
EXA24_RS10960	COG0482	sulfurtransferase activity
EXA24_RS10965	COG1760	l-serine dehydratase
EXA24_RS10970	COG1760	l-serine dehydratase
EXA24_RS10975	COG0741	lytic transglycosylase activity
EXA24_RS11000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXA24_RS11005	COG0612	Peptidase, M16
EXA24_RS11010	COG0612	Peptidase, M16
EXA24_RS11015	COG2501	S4 domain
EXA24_RS11035	COG0517	IMP dehydrogenase activity
EXA24_RS11035	COG0516	GMP reductase activity
EXA24_RS11045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXA24_RS11060	COG0454	-acetyltransferase
EXA24_RS11075	COG0549	Belongs to the carbamate kinase family
EXA24_RS11090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXA24_RS11095	COG0488	(ABC) transporter
EXA24_RS11100	COG4485	Bacterial membrane protein, YfhO
EXA24_RS11120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXA24_RS11125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXA24_RS11130	COG1475	DNA binding