locus-tag	class	description
C2E46_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C2E46_RS00015	ENOG4105CBD	Diacylglycerol kinase
C2E46_RS00030	ENOG4105C3G	gtp-binding protein
C2E46_RS00040	ENOG4108JA2	transcriptioN-repair coupling factor
C2E46_RS00050	ENOG41082I2	s4 domain protein
C2E46_RS00070	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C2E46_RS00075	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C2E46_RS00080	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C2E46_RS00260	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C2E46_RS00265	ENOG4105CHM	Aminotransferase
C2E46_RS00280	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C2E46_RS00285	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2E46_RS00290	ENOG4105C8V	SAICAR synthetase
C2E46_RS00295	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C2E46_RS00300	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C2E46_RS00305	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C2E46_RS00310	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C2E46_RS00320	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C2E46_RS00345	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
C2E46_RS00350	ENOG4105DRS	transport system, permease
C2E46_RS00375	ENOG4105I82	acetyl xylan esterase
C2E46_RS00390	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C2E46_RS00420	ENOG4105C83	adenylosuccinate lyase
C2E46_RS00435	ENOG4105KJF	protein tyrosine phosphatase
C2E46_RS00445	ENOG4105EXC	Acyl-transferase
C2E46_RS00450	ENOG4108EKI	Dehydrogenase
C2E46_RS00460	ENOG4105D98	threonine synthase
C2E46_RS00465	ENOG4105UQX	Mate efflux family protein
C2E46_RS00485	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C2E46_RS00575	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C2E46_RS00580	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C2E46_RS00605	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2E46_RS00695	ENOG4105D5G	Transposase
C2E46_RS00725	ENOG4105G7B	Protein of unknown function (DUF2992)
C2E46_RS00730	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS00750	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C2E46_RS00760	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2E46_RS00780	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C2E46_RS00785	ENOG4105DWF	phosphomethylpyrimidine kinase
C2E46_RS00790	ENOG4105PUK	Membrane
C2E46_RS00795	ENOG4108UIC	UPF0340 protein
C2E46_RS00800	ENOG4105D8X	mechanosensitive ion channel
C2E46_RS00830	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C2E46_RS00845	ENOG4107QN2	dihydrolipoyl dehydrogenase
C2E46_RS00850	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C2E46_RS00855	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C2E46_RS00860	ENOG4105CNN	ABC, transporter
C2E46_RS00875	ENOG4108RVA	ribokinase
C2E46_RS00880	ENOG4105ETE	Transcriptional regulator (LacI family
C2E46_RS00890	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2E46_RS00895	ENOG4108STX	response regulator
C2E46_RS00900	ENOG4105BZU	Histidine kinase
C2E46_RS00910	ENOG4105CH7	arginosuccinase
C2E46_RS00915	ENOG4105D2N	Aldolase
C2E46_RS00935	ENOG4105DP4	dak2 domain fusion protein ylov
C2E46_RS00955	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS00960	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS00970	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C2E46_RS00975	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
C2E46_RS00980	ENOG4105ESV	Glycosyl transferase, family 4
C2E46_RS00990	ENOG4105JRK	feS assembly protein SufD
C2E46_RS00995	ENOG4105C9B	Cysteine desulfurase
C2E46_RS01000	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C2E46_RS01005	ENOG4105DIW	FeS assembly protein SUFB
C2E46_RS01010	ENOG4105DZ1	carboxypeptidase
C2E46_RS01020	ENOG4108J59	Extracellular solute-binding protein, family 5
C2E46_RS01025	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2E46_RS01030	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2E46_RS01040	ENOG4108JQ7	(ABC) transporter
C2E46_RS01080	ENOG4105FDK	ABC transporter
C2E46_RS01100	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C2E46_RS01105	ENOG4105BZ4	penicillin-binding protein
C2E46_RS01195	ENOG4105II7	pyrroline-5-carboxylate reductase
C2E46_RS01200	ENOG4105CN9	Peptidase m42 family protein
C2E46_RS01220	ENOG4108VDD	TRNA binding domain protein
C2E46_RS01235	ENOG4107YBY	Hydrolase
C2E46_RS01240	ENOG4108HRK	Histidine kinase
C2E46_RS01245	ENOG4105DY9	regulatoR
C2E46_RS01250	ENOG41083D3	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity)
C2E46_RS01255	ENOG41067MG	lrgb family
C2E46_RS01270	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2E46_RS01275	ENOG4108JJB	ABC transporter
C2E46_RS01285	ENOG4105C5Y	PTS System
C2E46_RS01290	ENOG4105CG3	alpha amylase, catalytic region
C2E46_RS01295	ENOG4106ETB	IIa component
C2E46_RS01310	ENOG4108HHA	Transketolase
C2E46_RS01315	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C2E46_RS01320	ENOG4105E3J	oxidoreductase
C2E46_RS01340	ENOG4105D7W	serine acetyltransferase
C2E46_RS01350	ENOG4105C8N	cysteinyl-tRNA synthetase
C2E46_RS01355	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C2E46_RS01360	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C2E46_RS01375	ENOG4105VZ8	Transcriptional regulator
C2E46_RS01380	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C2E46_RS01400	ENOG4105VRS	hydrolase family 18
C2E46_RS01460	ENOG4106BHR	ftsk SpoIIIE family protein
C2E46_RS01480	ENOG41067QW	Transcriptional regulator
C2E46_RS01510	ENOG41067QW	Transcriptional regulator
C2E46_RS01515	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2E46_RS01580	ENOG4105CVR	type I restriction-modification system
C2E46_RS01585	ENOG4105EKX	Restriction modification system DNA (Specificity
C2E46_RS01590	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2E46_RS01595	ENOG4105EKX	Restriction modification system DNA (Specificity
C2E46_RS01610	ENOG4105DZR	Type I site-specific deoxyribonuclease
C2E46_RS01615	ENOG4105CB5	ATP-dependent DNA helicase recG
C2E46_RS01630	ENOG4105WT3	Transcriptional regulator
C2E46_RS01635	ENOG4107Y80	Major Facilitator superfamily
C2E46_RS01645	ENOG4108HQR	Glycine betaine
C2E46_RS01750	ENOG4105WT3	Transcriptional regulator
C2E46_RS01770	ENOG4105BZ1	(ABC) transporter
C2E46_RS01805	ENOG410630P	Transcriptional regulator
C2E46_RS01835	ENOG4105CE4	GlcNAc 6-P deacetylase
C2E46_RS01840	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
C2E46_RS01855	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C2E46_RS01860	ENOG4105VPS	UPF0291 protein
C2E46_RS01875	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C2E46_RS01880	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2E46_RS01885	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C2E46_RS01905	ENOG4105CJ1	ABC, transporter
C2E46_RS01915	ENOG4105C5Y	PTS System
C2E46_RS01925	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C2E46_RS01930	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C2E46_RS01940	ENOG4105CJN	penicillin-binding protein
C2E46_RS01950	ENOG4105C1J	atp-dependent rna helicase
C2E46_RS01955	ENOG4105EAB	amino acid AbC transporter
C2E46_RS01960	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS01965	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS01975	ENOG4105C3M	thioredoxin reductase
C2E46_RS01980	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C2E46_RS01990	ENOG4105CTZ	aminopeptidase c
C2E46_RS01995	ENOG4105BZ4	penicillin-binding protein
C2E46_RS02005	ENOG4108UKS	UPF0398 protein
C2E46_RS02020	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C2E46_RS02025	ENOG41070VT	
C2E46_RS02040	ENOG4108M15	ABC transporter
C2E46_RS02075	ENOG4105C25	Primosomal protein n'
C2E46_RS02085	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2E46_RS02095	ENOG4105D9P	serine threonine protein kinase
C2E46_RS02105	ENOG4105ENE	Histidine kinase
C2E46_RS02110	ENOG4105WH1	Two component transcriptional regulator luxr family
C2E46_RS02125	ENOG4105F1A	Pyruvate formate-lyase
C2E46_RS02130	ENOG4107EDW	L-fucose operon activator
C2E46_RS02135	ENOG4105DKT	Transcriptional regulator
C2E46_RS02145	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS02160	ENOG4105CK1	PTS System
C2E46_RS02165	ENOG4105C6N	Formate acetyltransferase
C2E46_RS02185	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C2E46_RS02195	ENOG41081UC	Inherit from COG: Competence protein
C2E46_RS02230	ENOG4105CFH	Aspartokinase
C2E46_RS02235	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C2E46_RS02240	ENOG4105CGU	Enoyl-CoA hydratase
C2E46_RS02255	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2E46_RS02260	ENOG4105EA8	2-Nitropropane dioxygenase
C2E46_RS02265	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C2E46_RS02270	ENOG4105CHR	reductase
C2E46_RS02290	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2E46_RS02335	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2E46_RS02340	ENOG4105ETZ	PTS System
C2E46_RS02350	ENOG4108KP7	hydrolase
C2E46_RS02365	ENOG4105C7N	Xanthine uracil vitamin C permease
C2E46_RS02370	ENOG4105K8N	protein family UPF0079, ATPase
C2E46_RS02375	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2E46_RS02380	ENOG4108KGH	TRANSCRIPTIONal
C2E46_RS02395	ENOG4105K59	histidine triad (HIT) protein
C2E46_RS02435	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C2E46_RS02440	ENOG4105CHV	Transcription elongation factor NusA
C2E46_RS02445	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
C2E46_RS02470	ENOG4105NA0	Transcriptional regulator
C2E46_RS02485	ENOG4105EN6	Membrane
C2E46_RS02495	ENOG4105C2M	dna polymerase I
C2E46_RS02500	ENOG4105K4P	CoA-binding domain protein
C2E46_RS02505	ENOG4105G5W	regulator Fur family
C2E46_RS02520	ENOG4108YBA	Histidine kinase
C2E46_RS02540	ENOG41080Y5	BioY family
C2E46_RS02545	ENOG4108RQ5	Beta-lactamase domain-containing protein
C2E46_RS02565	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C2E46_RS02570	ENOG4107ZXI	Rhomboid family
C2E46_RS02575	ENOG4105DIH	basic membrane
C2E46_RS02580	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2E46_RS02595	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2E46_RS02670	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2E46_RS02675	ENOG4105D5G	Transposase
C2E46_RS02710	ENOG4105D5G	Transposase
C2E46_RS02740	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C2E46_RS02750	ENOG4105VUF	Transcriptional regulator
C2E46_RS02775	ENOG4105ECQ	AraC Family Transcriptional Regulator
C2E46_RS02815	ENOG41068WN	
C2E46_RS02850	ENOG4105UNS	Pfam:DUF419
C2E46_RS02865	ENOG4106H78	methyltransferase
C2E46_RS02880	ENOG41063PX	domain protein
C2E46_RS02885	ENOG4107R8B	5'-nucleotidase
C2E46_RS02890	ENOG4105MMD	transcriptional regulator
C2E46_RS02905	ENOG4105BZ1	(ABC) transporter
C2E46_RS02910	ENOG4105BZ1	(ABC) transporter
C2E46_RS02915	ENOG4105DDQ	anthranilate synthase
C2E46_RS02930	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C2E46_RS02950	ENOG4105CSM	endonuclease III
C2E46_RS02965	ENOG4105DKQ	ROK family
C2E46_RS02970	ENOG4107YZP	Rhodanese domain protein
C2E46_RS02975	ENOG4105CI3	gtp-binding protein typa
C2E46_RS02985	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C2E46_RS03010	ENOG4105DFA	alanine racemase domain protein
C2E46_RS03020	ENOG4108VIA	integral membrane protein
C2E46_RS03025	ENOG4105DBK	s4 domain protein
C2E46_RS03030	ENOG4105MMF	Cell division protein DIVIVA
C2E46_RS03035	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C2E46_RS03045	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2E46_RS03055	ENOG4107IN1	Protein of unknown function (DUF1797)
C2E46_RS03060	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS03065	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS03070	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS03085	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C2E46_RS03090	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2E46_RS03105	ENOG4105DX0	Hemolysin A
C2E46_RS03110	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C2E46_RS03115	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C2E46_RS03120	ENOG4108RCR	degv family
C2E46_RS03125	ENOG41090WU	lipolytic protein G-D-S-L family
C2E46_RS03135	ENOG4105K70	DNA-binding protein
C2E46_RS03180	ENOG4105DCI	Phosphohydrolase
C2E46_RS03200	ENOG4105D5G	Transposase
C2E46_RS03215	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C2E46_RS03225	ENOG4105CAK	Cell division ATP-binding protein ftsE
C2E46_RS03230	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C2E46_RS03250	ENOG4105CHR	reductase
C2E46_RS03255	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS03260	ENOG4105DVT	helicase
C2E46_RS03265	ENOG4105CHM	Aminotransferase
C2E46_RS03315	ENOG41082DI	50s ribosomal protein l31
C2E46_RS03320	ENOG4105SFS	phosphoesterase RecJ domain protein
C2E46_RS03325	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C2E46_RS03330	ENOG4105NQC	Flavodoxin
C2E46_RS03335	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2E46_RS03340	ENOG4107R4J	Chloride channel
C2E46_RS03415	ENOG4105EAC	phosphoserine phosphatase
C2E46_RS03450	ENOG4108KGH	TRANSCRIPTIONal
C2E46_RS03455	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2E46_RS03465	ENOG4108A04	Beta-lactamase
C2E46_RS03470	ENOG4108IUW	ABC transporter
C2E46_RS03500	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2E46_RS03505	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C2E46_RS03525	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C2E46_RS03530	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2E46_RS03555	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS03560	ENOG4105C9K	Endothelin-converting enzyme 1
C2E46_RS03565	ENOG4105C9K	Endothelin-converting enzyme 1
C2E46_RS03600	ENOG4105ZT7	DNA-entry nuclease
C2E46_RS03610	ENOG4105DQR	SNARE associated Golgi
C2E46_RS03615	ENOG41083J0	(ABC) transporter
C2E46_RS03620	ENOG4105C4B	ABC transporter, permease
C2E46_RS03630	ENOG4105C5Q	Transcriptional regulator
C2E46_RS03640	ENOG4105C5I	Dehydrogenase
C2E46_RS03645	ENOG4105CT4	transporter
C2E46_RS03655	ENOG4105CNT	hydrolase family 2
C2E46_RS03660	ENOG4107YCY	Transcriptional regulator
C2E46_RS03665	ENOG4108UHU	Aldolase
C2E46_RS03675	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
C2E46_RS03680	ENOG4105DMW	Dehydrogenase reductase
C2E46_RS03690	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C2E46_RS03700	ENOG4105ETE	Transcriptional regulator (LacI family
C2E46_RS03710	ENOG4105W2C	Glycosyl transferase
C2E46_RS03715	ENOG4105BZF	Glycosyl transferase (Group 1
C2E46_RS03745	ENOG4105DRP	amino acid AbC transporter
C2E46_RS03750	ENOG4105EAD	ABC transporter
C2E46_RS03755	ENOG4107RP9	extracellular solute-binding protein, family 3
C2E46_RS03760	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS03765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2E46_RS03770	ENOG4105BZU	Histidine kinase
C2E46_RS03775	ENOG4105Q2H	domain protein
C2E46_RS03780	ENOG4105WD1	Membrane
C2E46_RS03790	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C2E46_RS03825	ENOG4105E5H	Transposase
C2E46_RS03875	ENOG4105C2M	dna polymerase I
C2E46_RS03940	ENOG4105DVF	Cytosine-specific methyltransferase
C2E46_RS03980	ENOG4105EFC	phage portal protein HK97 family
C2E46_RS03985	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C2E46_RS04045	ENOG4105XSJ	toxin secretion phage lysis holin
C2E46_RS04050	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
C2E46_RS04075	ENOG410667J	hydrolase
C2E46_RS04080	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C2E46_RS04085	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS04090	ENOG4108NNR	transporter substrate-binding protein
C2E46_RS04095	ENOG4108PJD	permease
C2E46_RS04115	ENOG410906U	SprT-like
C2E46_RS04120	ENOG41067S9	phage shock protein C, PspC
C2E46_RS04160	ENOG4105CFP	Peptidase U32
C2E46_RS04165	ENOG4105VEM	Conserved domain protein
C2E46_RS04175	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C2E46_RS04185	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C2E46_RS04190	ENOG4108R6K	riboflavin synthase, subunit alpha
C2E46_RS04195	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C2E46_RS04205	ENOG4105CRK	lysyL-tRNA synthetase
C2E46_RS04220	ENOG4108Z66	YbaK ebsC protein
C2E46_RS04250	ENOG4105DPN	Oligoendopeptidase f
C2E46_RS04260	ENOG4105CNI	cell division protein FtsW
C2E46_RS04280	ENOG4107RF6	penicillin-binding protein
C2E46_RS04295	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C2E46_RS04300	ENOG4105FCD	Major Facilitator
C2E46_RS04320	ENOG4105KWG	Pfam:DUF1696
C2E46_RS04325	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C2E46_RS04330	ENOG4108UMI	ABC transporter, permease
C2E46_RS04335	ENOG4105D01	(LipO)protein
C2E46_RS04340	ENOG4105C1J	atp-dependent rna helicase
C2E46_RS04350	ENOG41060K3	Methyltransferase
C2E46_RS04355	ENOG4105F6E	Acyl-transferase
C2E46_RS04360	ENOG4105KQC	Competence protein
C2E46_RS04365	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C2E46_RS04370	ENOG4108X4Q	Hydrolase
C2E46_RS04385	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C2E46_RS04395	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2E46_RS04400	ENOG4105CID	antiterminator
C2E46_RS04405	ENOG4105C5Y	PTS System
C2E46_RS04420	ENOG4105BZW	Glycerate kinase
C2E46_RS04425	ENOG4107QQ0	gntp family
C2E46_RS04435	ENOG4105K56	Transcriptional regulator
C2E46_RS04440	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C2E46_RS04455	ENOG4105CHF	Glutathione S-transferase
C2E46_RS04480	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C2E46_RS04485	ENOG4108VQJ	O-methyltransferase
C2E46_RS04510	ENOG4105X1N	Glycosyl transferase family 8
C2E46_RS04520	ENOG4105VZ8	Transcriptional regulator
C2E46_RS04535	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2E46_RS04540	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2E46_RS04545	ENOG41067VN	Glutaredoxin
C2E46_RS04550	ENOG4105KRI	phosphocarrier protein (HPr
C2E46_RS04555	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C2E46_RS04560	ENOG4105C26	Dehydrogenase
C2E46_RS04565	ENOG4108ZJ4	polysaccharide deacetylase
C2E46_RS04570	ENOG4105FDU	atp-dependent rna helicase
C2E46_RS04585	ENOG4105C6E	dna polymerase iii
C2E46_RS04595	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C2E46_RS04600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C2E46_RS04630	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
C2E46_RS04635	ENOG4108JJB	ABC transporter
C2E46_RS04645	ENOG4105JH5	thiaminase II
C2E46_RS04655	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C2E46_RS04665	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C2E46_RS04680	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C2E46_RS04690	ENOG4105WH5	Teichoic acid glycosylation protein
C2E46_RS04695	ENOG410807C	QueT transporter
C2E46_RS04700	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C2E46_RS04705	ENOG4105CBD	Diacylglycerol kinase
C2E46_RS04710	ENOG4108IUM	Glycogen debranching enzyme
C2E46_RS04720	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C2E46_RS04735	ENOG4105ZA1	atp synthase
C2E46_RS04750	ENOG4108BGU	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2E46_RS04770	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C2E46_RS04790	ENOG4105ZT7	DNA-entry nuclease
C2E46_RS04805	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C2E46_RS04810	ENOG4105CGZ	zinc metallopeptidase
C2E46_RS04820	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C2E46_RS04830	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C2E46_RS04835	ENOG4105C5H	ABC transporter
C2E46_RS04840	ENOG4107RUY	(E1 component), alpha subunit
C2E46_RS04845	ENOG4105CPP	Dehydrogenase, E1 component
C2E46_RS04850	ENOG4107QKR	Dehydrogenase
C2E46_RS04855	ENOG4107QN2	dihydrolipoyl dehydrogenase
C2E46_RS04860	ENOG4105DF9	Lipoate-protein, ligase
C2E46_RS04865	ENOG4105F1K	Glutamine amidotransferase
C2E46_RS04870	ENOG4105DMS	mur ligase
C2E46_RS04875	ENOG4105C8B	TIGR00159 family
C2E46_RS04905	ENOG4105CSA	Coproporphyrinogen iii oxidase
C2E46_RS04915	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C2E46_RS04925	ENOG4107SFZ	crispr-associated protein
C2E46_RS04940	ENOG4108V16	CRISPR-associated protein
C2E46_RS04960	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS04970	ENOG4105K5X	acetyltransferase
C2E46_RS05010	ENOG41067QW	Transcriptional regulator
C2E46_RS05070	ENOG4105XB7	anti-repressor protein
C2E46_RS05115	ENOG4105F5W	AtP-binding protein
C2E46_RS05335	ENOG4105CZV	ABC transporter
C2E46_RS05340	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
C2E46_RS05355	ENOG4105CA9	Pyruvate kinase
C2E46_RS05365	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C2E46_RS05370	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C2E46_RS05375	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS05380	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS05400	ENOG4107Y49	methyltransferase
C2E46_RS05410	ENOG4105DIH	basic membrane
C2E46_RS05415	ENOG4108JQ9	ABC transporter
C2E46_RS05420	ENOG4105UIB	(ABC) transporter
C2E46_RS05450	ENOG4108Z6X	(sortase) family
C2E46_RS05455	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C2E46_RS05480	ENOG4105FDP	GntR family transcriptional regulator
C2E46_RS05485	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
C2E46_RS05495	ENOG4105D01	(LipO)protein
C2E46_RS05525	ENOG4105EWM	Histidine kinase
C2E46_RS05550	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2E46_RS05555	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
C2E46_RS05560	ENOG4105US7	Histidine kinase
C2E46_RS05565	ENOG4108STX	response regulator
C2E46_RS05575	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C2E46_RS05590	ENOG4105E2Z	phosphate ABC transporter (Permease
C2E46_RS05595	ENOG4105C8U	phosphate abc transporter
C2E46_RS05600	ENOG4105CVA	phosphate
C2E46_RS05605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2E46_RS05620	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
C2E46_RS05625	ENOG4105DTN	riboflavin biosynthesis protein ribF
C2E46_RS05660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2E46_RS05665	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2E46_RS05670	ENOG4105C79	DNA protecting protein DprA
C2E46_RS05675	ENOG4108HUF	Transporter
C2E46_RS05680	ENOG4108IPW	abc transporter atp-binding protein
C2E46_RS05685	ENOG4105CM4	permease protein
C2E46_RS05690	ENOG4105DHS	permease protein
C2E46_RS05695	ENOG4108UW5	maltose o-acetyltransferase
C2E46_RS05700	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2E46_RS05705	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C2E46_RS05710	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
C2E46_RS05720	ENOG4105DY9	regulatoR
C2E46_RS05725	ENOG4108HRK	Histidine kinase
C2E46_RS05855	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C2E46_RS05865	ENOG4105CD3	dihydroorotase
C2E46_RS05870	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C2E46_RS05875	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C2E46_RS05885	ENOG4105C5H	ABC transporter
C2E46_RS05895	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C2E46_RS05910	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2E46_RS05950	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
C2E46_RS05960	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C2E46_RS05965	ENOG4105FH5	Membrane
C2E46_RS05975	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS05985	ENOG4105BZ1	(ABC) transporter
C2E46_RS05995	ENOG41065S2	pneumococcal vaccine antigen
C2E46_RS06015	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C2E46_RS06020	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C2E46_RS06045	ENOG4107EFR	Flavocytochrome c
C2E46_RS06075	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2E46_RS06090	ENOG4105EMU	Dehydrogenase
C2E46_RS06095	ENOG4108IJ2	phosphate acetyltransferase
C2E46_RS06100	ENOG4105EMS	pseudouridine synthase
C2E46_RS06120	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C2E46_RS06125	ENOG4105C3J	Cysteine desulfurase
C2E46_RS06150	ENOG4105CS2	ec 3.2.1.21
C2E46_RS06160	ENOG4108HCJ	Hydrolase
C2E46_RS06165	ENOG4105E7U	AraC family transcriptional regulator
C2E46_RS06170	ENOG4105CMQ	Chloride channel
C2E46_RS06175	ENOG4107RUE	extracellular solute-binding protein family 1
C2E46_RS06180	ENOG4105D38	putrescine abc transporter
C2E46_RS06185	ENOG4105F38	ABC transporter, permease
C2E46_RS06200	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2E46_RS06205	ENOG4105KRF	dihydroneopterin aldolase
C2E46_RS06220	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C2E46_RS06225	ENOG4105FR1	rard protein
C2E46_RS06235	ENOG4105D6E	homoserine dehydrogenase
C2E46_RS06250	ENOG4105C26	Dehydrogenase
C2E46_RS06300	ENOG4105VBF	alkaline shock protein
C2E46_RS06310	ENOG4105VBF	alkaline shock protein
C2E46_RS06335	ENOG4105C4R	Atp-dependent dna helicase
C2E46_RS06350	ENOG4105BZG	amino acid carrier protein
C2E46_RS06365	ENOG41067MG	lrgb family
C2E46_RS06385	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C2E46_RS06405	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C2E46_RS06415	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2E46_RS06420	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C2E46_RS06450	ENOG4105D2T	synthase
C2E46_RS06455	ENOG4108MY6	biosynthesis protein
C2E46_RS06495	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C2E46_RS06520	ENOG4108KGH	TRANSCRIPTIONal
C2E46_RS06545	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
C2E46_RS06570	ENOG4107UWA	esterase
C2E46_RS06580	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2E46_RS06595	ENOG4105F23	Fibronectin-binding protein
C2E46_RS06600	ENOG4107FQX	Alpha-acetolactate decarboxylase
C2E46_RS06610	ENOG41068YB	TPR repeat-containing protein
C2E46_RS06630	ENOG4106AM8	polysaccharide lyase family 8
C2E46_RS06635	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C2E46_RS06640	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C2E46_RS06650	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C2E46_RS06655	ENOG4107VFR	oxidoreductase
C2E46_RS06660	ENOG4105EGD	dinuclear metal center protein, YbgI family
C2E46_RS06675	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C2E46_RS06685	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C2E46_RS06690	ENOG4108IXY	short-chain dehydrogenase reductase
C2E46_RS06705	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C2E46_RS06735	ENOG4108RG0	uracil-dna glycosylase
C2E46_RS06740	ENOG4107QSE	Dipeptidase
C2E46_RS06750	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C2E46_RS06760	ENOG4105WPN	DNA integration recombination invertion protein
C2E46_RS06765	ENOG4107QMU	Mate efflux family protein
C2E46_RS06790	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2E46_RS06800	ENOG4108IMY	Transcriptional regulator
C2E46_RS06815	ENOG4105DA5	(ABC) transporter
C2E46_RS06850	ENOG4105MU5	relaxase mobilization nuclease domain protein
C2E46_RS06875	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2E46_RS06930	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS06980	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS07040	ENOG4105DVF	Cytosine-specific methyltransferase
C2E46_RS07065	ENOG4107QK5	Homocysteine s-methyltransferase
C2E46_RS07070	ENOG4108IQI	permease
C2E46_RS07100	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C2E46_RS07110	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C2E46_RS07125	ENOG4108UT2	hemolysin iii
C2E46_RS07145	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C2E46_RS07170	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2E46_RS07195	ENOG4105CGH	5'-nucleotidase
C2E46_RS07200	ENOG4107YDN	peptide deformylase
C2E46_RS07205	ENOG4107R37	Glutamate dehydrogenase
C2E46_RS07215	ENOG4105BZ1	(ABC) transporter
C2E46_RS07220	ENOG4105BZ1	(ABC) transporter
C2E46_RS07230	ENOG4105C5H	ABC transporter
C2E46_RS07235	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C2E46_RS07260	ENOG4105DM4	PTS System
C2E46_RS07265	ENOG4105DE4	1-phosphofructokinase
C2E46_RS07270	ENOG4105E98	transcriptional regulator DeoR family
C2E46_RS07275	ENOG4107X35	defense response to bacterium
C2E46_RS07305	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C2E46_RS07325	ENOG4105VB6	UPF0109 protein
C2E46_RS07335	ENOG4107RBB	ABC transporter, permease
C2E46_RS07340	ENOG4105C19	ABC transporter
C2E46_RS07345	ENOG4107X8C	Efflux transporter RND family MFP subunit
C2E46_RS07360	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C2E46_RS07370	ENOG4105C34	Pseudouridine synthase
C2E46_RS07380	ENOG4105CN8	Transcriptional regulator
C2E46_RS07385	ENOG4105K46	50S ribosomal protein l27
C2E46_RS07405	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
C2E46_RS07410	ENOG4105C3J	Cysteine desulfurase
C2E46_RS07420	ENOG4105DC8	reductase
C2E46_RS07445	ENOG4105DR4	Methyltransferase
C2E46_RS07450	ENOG4105D5G	Transposase
C2E46_RS07455	ENOG4105E0M	Sulfatase
C2E46_RS07505	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C2E46_RS07510	ENOG4105E0A	ABC, transporter
C2E46_RS07520	ENOG4105DQ5	transport system permease protein
C2E46_RS07525	ENOG4105EHG	Permease protein
C2E46_RS07540	ENOG4105F1A	Pyruvate formate-lyase
C2E46_RS07555	ENOG4105N5T	Radical SAM Protein
C2E46_RS07560	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2E46_RS07565	ENOG4108SAX	Membrane
C2E46_RS07610	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C2E46_RS07650	ENOG4105KPE	licD family
C2E46_RS07665	ENOG4105CKK	Glycosyl transferase, family 2
C2E46_RS07670	ENOG4105K64	Glycosyl transferase, family 2
C2E46_RS07680	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C2E46_RS07685	ENOG4105VG1	fes assembly suf system protein
C2E46_RS07690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2E46_RS07695	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C2E46_RS07700	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C2E46_RS07715	ENOG4105EAB	amino acid AbC transporter
C2E46_RS07720	ENOG4105BZU	Histidine kinase
C2E46_RS07725	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
C2E46_RS07745	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
C2E46_RS07750	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
C2E46_RS07755	ENOG4105FKQ	transcriptional regulator
C2E46_RS07770	ENOG4105EG2	ABC transporter, permease
C2E46_RS07775	ENOG4105DUX	Transporter
C2E46_RS07790	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
C2E46_RS07850	ENOG4105GH9	galactofuranosyltransferase
C2E46_RS07860	ENOG4105D5G	Transposase
C2E46_RS07880	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS07885	ENOG4105CDA	abc transporter atp-binding protein
C2E46_RS07890	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS07915	ENOG4105C88	aminopeptidase
C2E46_RS07945	ENOG4108RCM	Nitroreductase
C2E46_RS07955	ENOG4105CKK	Glycosyl transferase, family 2
C2E46_RS07960	ENOG4105C85	amino acid
C2E46_RS07970	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C2E46_RS07985	ENOG4105C6X	Major Facilitator
C2E46_RS07995	ENOG4105DA5	(ABC) transporter
C2E46_RS08035	ENOG4105D5G	Transposase
C2E46_RS08055	ENOG4107YR5	Diacylglycerol kinase
C2E46_RS08080	ENOG4105C9A	Phoh family
C2E46_RS08120	ENOG4105C3U	ABC transporter
C2E46_RS08125	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2E46_RS08135	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
C2E46_RS08145	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C2E46_RS08170	ENOG4105CRQ	synthase (Component I)
C2E46_RS08175	ENOG4105CNU	cell division protein FtsK
C2E46_RS08180	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C2E46_RS08185	ENOG4105CC5	ABC transporter
C2E46_RS08190	ENOG4105DIK	(ABC) transporter
C2E46_RS08205	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C2E46_RS08255	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C2E46_RS08280	ENOG4107QJZ	Glycosyl transferase, family 2
C2E46_RS08305	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS08315	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C2E46_RS08320	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C2E46_RS08335	ENOG4105CK1	PTS System
C2E46_RS08345	ENOG4105CGK	Exodeoxyribonuclease III
C2E46_RS08350	ENOG41080E8	Transcriptional regulator, Spx MgsR family
C2E46_RS08355	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C2E46_RS08360	ENOG4108JQ1	Dehydrogenase
C2E46_RS08370	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C2E46_RS08380	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C2E46_RS08390	ENOG4105FA2	dna polymerase iii
C2E46_RS08400	ENOG41080XP	Cbs domain
C2E46_RS08405	ENOG4108IV0	ABC, transporter
C2E46_RS08410	ENOG4105C0Z	ABC transporter
C2E46_RS08415	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C2E46_RS08420	ENOG4105C32	Amino acid ABC transporter (Permease)
C2E46_RS08445	ENOG4105C87	Aminotransferase class I and II
C2E46_RS08455	ENOG4107R7I	amino acid
C2E46_RS08460	ENOG4105C1A	potassium transporter peripheral membrane
C2E46_RS08465	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C2E46_RS08475	ENOG4105FE9	pseudouridine synthase
C2E46_RS08505	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C2E46_RS08510	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C2E46_RS08520	ENOG4105RNB	
C2E46_RS08540	ENOG4108RWN	rrna methyltransferase
C2E46_RS08555	ENOG4105E5Q	amino acid AbC transporter
C2E46_RS08560	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
C2E46_RS08595	ENOG4105C0D	helicase
C2E46_RS08620	ENOG4105GR3	Histidine kinase
C2E46_RS08625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2E46_RS08635	ENOG4105D0M	Protease HtpX homolog
C2E46_RS08640	ENOG4108V0P	LemA family
C2E46_RS08645	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C2E46_RS08655	ENOG4107ZYR	domain protein
C2E46_RS08665	ENOG4108JJB	ABC transporter
C2E46_RS08685	ENOG4105E2A	Dehydrogenase
C2E46_RS08705	ENOG4105D01	(LipO)protein
C2E46_RS08725	ENOG4105CMT	Dihydroxyacetone kinase
C2E46_RS08735	ENOG4105CMT	Dihydroxyacetone kinase
C2E46_RS08740	ENOG4108UTZ	Dihydroxyacetone kinase
C2E46_RS08745	ENOG4105VDH	Dihydroxyacetone kinase
C2E46_RS08750	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2E46_RS08765	ENOG4105CDE	UPF0348 protein
C2E46_RS08775	ENOG4105DXX	methyltransferase
C2E46_RS08780	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C2E46_RS08790	ENOG4108WF2	Metal Dependent Phosphohydrolase
C2E46_RS08795	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C2E46_RS08800	ENOG410812S	Rna-binding protein
C2E46_RS08805	ENOG4105CQW	ribosome biogenesis GTPase YqeH
C2E46_RS08810	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
C2E46_RS08825	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C2E46_RS08830	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C2E46_RS08835	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C2E46_RS08860	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
C2E46_RS08865	ENOG4105CHM	Aminotransferase
C2E46_RS08870	ENOG4107YZX	Universal stress protein
C2E46_RS08880	ENOG4107RB3	L-asparaginase
C2E46_RS08890	ENOG4107RGM	aldo keto reductase
C2E46_RS08895	ENOG4105CB5	ATP-dependent DNA helicase recG
C2E46_RS08900	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
C2E46_RS08915	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2E46_RS08925	ENOG4105DG6	mannose-6-phosphate isomerase
C2E46_RS08930	ENOG4105EVU	fructokinase
C2E46_RS08935	ENOG4105C5Y	PTS System
C2E46_RS08945	ENOG4105ETE	Transcriptional regulator (LacI family
C2E46_RS08970	ENOG4105BZ1	(ABC) transporter
C2E46_RS09010	ENOG4108UK2	deaminase
C2E46_RS09015	ENOG4105DC7	peptidase M24
C2E46_RS09050	ENOG4108UUM	single-stranded DNA-binding protein
C2E46_RS09060	ENOG4105CEN	a g-specific adenine glycosylase
C2E46_RS09070	ENOG4105K63	Thioredoxin
C2E46_RS09100	ENOG4105C3F	Signal peptidase i
C2E46_RS09105	ENOG4105C7H	Helicase, RecD TraA family
C2E46_RS09125	ENOG4105C6N	Formate acetyltransferase
C2E46_RS09130	ENOG41090Y0	FMN-binding protein
C2E46_RS09135	ENOG4107QK9	Beta-lactamase
C2E46_RS09150	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2E46_RS09160	ENOG4105CZM	Major Facilitator
C2E46_RS09165	ENOG4105TV1	Transcriptional regulator
C2E46_RS09180	ENOG4105EAH	synthase
C2E46_RS09185	ENOG4108JJ8	(ABC) transporter
C2E46_RS09190	ENOG4108JJ9	ABC, transporter
C2E46_RS09195	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2E46_RS09200	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2E46_RS09205	ENOG4105CEP	NADH dehydrogenase
C2E46_RS09225	ENOG4108NUI	synthase
C2E46_RS09230	ENOG4107TXC	Transcriptional regulator
C2E46_RS09245	ENOG4105CBX	hi0933 family
C2E46_RS09270	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
C2E46_RS09275	ENOG41072GX	Peptidase M22 Glycoprotease
C2E46_RS09290	ENOG41068JE	domain protein
C2E46_RS09295	ENOG4105C5F	glutamine synthetase
C2E46_RS09300	ENOG4105KV4	Transcriptional regulator
C2E46_RS09315	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
C2E46_RS09320	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C2E46_RS09340	ENOG4105DFT	pur operon repressor
C2E46_RS09350	ENOG4107QSV	RmuC domain protein
C2E46_RS09360	ENOG4105DJV	ribulose-phosphate 3-epimerase
C2E46_RS09365	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C2E46_RS09385	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
C2E46_RS09390	ENOG4105F8V	Hydrolase, tatD family
C2E46_RS09415	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
C2E46_RS09425	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C2E46_RS09440	ENOG4105US7	Histidine kinase
C2E46_RS09445	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2E46_RS09455	ENOG4105DWD	nucleoside recognition domain protein
C2E46_RS09460	ENOG4105D5G	Transposase
C2E46_RS09470	ENOG4108IJ7	Glycine betaine
C2E46_RS09475	ENOG4107QRI	Phosphoketolase
C2E46_RS09495	ENOG4105CMG	Carbohydrate kinase
C2E46_RS09505	ENOG4105DT3	PTS system, galactitol-specific IIc component
C2E46_RS09510	ENOG4105C5I	Dehydrogenase
C2E46_RS09520	ENOG4108M60	Transcriptional regulator
C2E46_RS09525	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2E46_RS09555	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
C2E46_RS09575	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C2E46_RS09590	ENOG4105D9M	gamma-glutamylcysteine synthetase
C2E46_RS09610	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C2E46_RS09615	ENOG4105ZMH	deoxynucleoside kinase
C2E46_RS09625	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2E46_RS09645	ENOG4105CE9	30S ribosomal protein S2
C2E46_RS09650	ENOG4105D3R	alkyl hydroperoxide reductase
C2E46_RS09665	ENOG4107SUZ	Sodium/hydrogen exchanger family
C2E46_RS09680	ENOG4105C9K	Endothelin-converting enzyme 1
C2E46_RS09715	ENOG4105EKQ	RNA-directed DNA polymerase
C2E46_RS09720	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2E46_RS09725	ENOG4105ETZ	PTS System
C2E46_RS09730	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
C2E46_RS09735	ENOG4105EP8	Glycosyl Hydrolase Family 88
C2E46_RS09745	ENOG4105CHR	reductase
C2E46_RS09785	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C2E46_RS09790	ENOG4107X35	defense response to bacterium
C2E46_RS09805	ENOG4105KNE	Phosphatidate cytidylyltransferase
C2E46_RS09810	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C2E46_RS09815	ENOG4105VIE	preprotein translocase, subunit YajC
C2E46_RS09845	ENOG4108MRH	transcriptional regulatory protein
C2E46_RS09850	ENOG4105CMR	udp-glucose 4-epimerase
C2E46_RS09860	ENOG4108IJ9	(ABC) transporter
C2E46_RS09910	ENOG4105CK1	PTS System
C2E46_RS09915	ENOG4105VCP	PTS System
C2E46_RS09945	ENOG4108YZA	Nitrogen regulatory protein pii
C2E46_RS09950	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C2E46_RS09955	ENOG4105DM4	PTS System
C2E46_RS09960	ENOG4105DE4	1-phosphofructokinase
C2E46_RS09965	ENOG4105QEK	Transcriptional regulator
C2E46_RS09995	ENOG4105D5G	Transposase
C2E46_RS10035	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C2E46_RS10045	ENOG4105CGH	5'-nucleotidase
C2E46_RS10055	ENOG4105DER	m42 family
C2E46_RS10070	ENOG4107VQW	regulatoR
C2E46_RS10075	ENOG4105C2F	Histidine kinase
C2E46_RS10080	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2E46_RS10085	ENOG4105ETZ	PTS System
C2E46_RS10100	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2E46_RS10110	ENOG4105DA5	(ABC) transporter
C2E46_RS10130	ENOG4105CI1	PTS System
C2E46_RS10135	ENOG4105BZU	Histidine kinase
C2E46_RS10140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2E46_RS10145	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C2E46_RS10150	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C2E46_RS10155	ENOG4105E2Z	phosphate ABC transporter (Permease
C2E46_RS10160	ENOG4105C8U	phosphate abc transporter
C2E46_RS10165	ENOG4107S17	Phosphate-binding protein
C2E46_RS10175	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C2E46_RS10180	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C2E46_RS10190	ENOG4107TXC	Transcriptional regulator
C2E46_RS10215	ENOG4105D1H	recombination factor protein RarA
C2E46_RS10225	ENOG4105VTR	Integrase
C2E46_RS10285	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C2E46_RS10320	ENOG41067QW	Transcriptional regulator
C2E46_RS10335	ENOG4106BHR	ftsk SpoIIIE family protein
C2E46_RS10425	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C2E46_RS10430	ENOG4106KKU	
C2E46_RS10435	ENOG4108Z15	abc transporter atp-binding protein
C2E46_RS10450	ENOG4105Y2Z	radical SAM domain protein
C2E46_RS10550	ENOG4106BHR	ftsk SpoIIIE family protein
C2E46_RS10635	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2E46_RS10640	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
C2E46_RS10675	ENOG4105KHC	sulfurtransferase
C2E46_RS10725	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2E46_RS10730	ENOG4105F3H	Histidine kinase
C2E46_RS10745	ENOG4107RGD	Major Facilitator superfamily
C2E46_RS10750	ENOG4108NRW	Phospholipase, patatin family
C2E46_RS10755	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C2E46_RS10775	ENOG4105BZ4	penicillin-binding protein
C2E46_RS10780	ENOG4108YBP	pseudouridine synthase
C2E46_RS10800	ENOG4105D9N	nucleoside
C2E46_RS10805	ENOG4108I5U	Uridine phosphorylase
C2E46_RS10825	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C2E46_RS10830	ENOG4105D7T	ABC transporter
C2E46_RS10835	ENOG4105C7J	ABC transporter, permease
C2E46_RS10845	ENOG410667J	hydrolase
C2E46_RS10850	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2E46_RS10855	ENOG4105D1Q	UPF0246 protein
C2E46_RS10860	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
C2E46_RS10870	ENOG4105EP9	oxidoreductase
C2E46_RS10875	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
C2E46_RS10885	ENOG4105VPH	UPF0473 protein
C2E46_RS10900	ENOG410888K	transcriptional regulator, Spx
C2E46_RS10905	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C2E46_RS10910	ENOG4105CEV	competence damage-inducible protein
C2E46_RS10915	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C2E46_RS10935	ENOG4105VEQ	Cold shock protein
C2E46_RS10940	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C2E46_RS10945	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C2E46_RS10960	ENOG4108JYZ	YitT family
C2E46_RS10965	ENOG4107AYK	membrAne
C2E46_RS10970	ENOG4105C9M	aspartyl-trna synthetase
C2E46_RS11050	ENOG4105D5G	Transposase
C2E46_RS11080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2E46_RS11090	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C2E46_RS11100	ENOG4105DBV	ornithine carbamoyltransferase
C2E46_RS11105	ENOG4105CUX	Signal transduction histidine kinase
C2E46_RS11115	ENOG4108IJ8	ABC transporter
C2E46_RS11120	ENOG4105E90	ABC transporter
C2E46_RS11135	ENOG4105KA3	membrAne
C2E46_RS11165	ENOG4105CDU	Replicative dna helicase
C2E46_RS11185	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C2E46_RS11190	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C2E46_RS11200	ENOG4105EJQ	L-serine dehydratase
C2E46_RS11205	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
C2E46_RS11210	ENOG41068KG	domain protein
C2E46_RS11230	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C2E46_RS11245	ENOG410848D	S4 domain protein YaaA
C2E46_RS11270	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2E46_RS11275	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C2E46_RS11290	ENOG4105CEU	Arginine dihydrolase
C2E46_RS11300	ENOG4105DBV	ornithine carbamoyltransferase
C2E46_RS11310	ENOG4105C5B	carbamate kinase
C2E46_RS11320	ENOG4105C31	Tryptophanyl-tRNA synthetase
C2E46_RS11335	ENOG4105C5H	ABC transporter
C2E46_RS11340	ENOG4105EJV	Membrane
C2E46_RS11365	ENOG4105C0H	protease
C2E46_RS11370	ENOG4105FA0	parb-like partition protein