locus-tag	class	description
SANR_RS00010	COG0592	DNA-directed DNA polymerase activity
SANR_RS00025	COG0012	GTP binding
SANR_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
SANR_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SANR_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SANR_RS00055	COG0037	tRNA processing
SANR_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SANR_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SANR_RS00185	COG1792	Involved in formation and maintenance of cell shape
SANR_RS00195	COG3942	CHAP domain
SANR_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SANR_RS00205	COG0436	Aminotransferase
SANR_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
SANR_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SANR_RS00225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SANR_RS00240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SANR_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SANR_RS00260	COG3942	CHAP domain
SANR_RS00265	COG0151	Belongs to the GarS family
SANR_RS00270	COG1683	Conserved Protein
SANR_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SANR_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SANR_RS00300	COG2376	Dihydroxyacetone kinase
SANR_RS00310	COG2376	Dihydroxyacetone kinase
SANR_RS00315	COG1461	Dihydroxyacetone kinase
SANR_RS00320	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SANR_RS00325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SANR_RS00345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS00355	COG3716	PTS system mannose fructose sorbose family IID component
SANR_RS00365	COG2222	sugar isomerase
SANR_RS00370	COG3684	Belongs to the aldolase LacD family
SANR_RS00385	COG2801	Transposase and inactivated derivatives
SANR_RS00390	COG2255	four-way junction helicase activity
SANR_RS00400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SANR_RS00415	COG1454	alcohol dehydrogenase
SANR_RS00415	COG1012	belongs to the aldehyde dehydrogenase family
SANR_RS00420	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SANR_RS00430	COG1175	transmembrane transport
SANR_RS00435	COG0395	ABC-type sugar transport system, permease component
SANR_RS00450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SANR_RS00470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS00470	COG1263	PTS System
SANR_RS00475	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SANR_RS00490	COG1269	ATP hydrolysis coupled proton transport
SANR_RS00495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SANR_RS00505	COG1527	subunit (C
SANR_RS00510	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SANR_RS00520	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SANR_RS00525	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SANR_RS00530	COG1394	ATPase activity, coupled to movement of substances
SANR_RS00535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SANR_RS00555	COG3759	membrane
SANR_RS00560	COG1914	H( )-stimulated, divalent metal cation uptake system
SANR_RS00590	COG1846	Transcriptional regulator
SANR_RS00595	COG1121	(ABC) transporter
SANR_RS00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SANR_RS00605	COG0803	Belongs to the bacterial solute-binding protein 9 family
SANR_RS00605	COG3443	Belongs to the bacterial solute-binding protein 9 family
SANR_RS00625	COG0564	pseudouridine synthase activity
SANR_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SANR_RS00745	COG1705	Flagellar rod assembly protein muramidase FlgJ
SANR_RS00745	COG3942	CHAP domain
SANR_RS00760	COG0433	COG0433 Predicted ATPase
SANR_RS00800	COG4115	mRNA cleavage
SANR_RS00810	COG1674	ftsk spoiiie
SANR_RS00845	COG1396	sequence-specific DNA binding
SANR_RS00875	COG1132	(ABC) transporter
SANR_RS00890	COG2081	HI0933 family
SANR_RS00905	COG0584	glycerophosphoryl diester phosphodiesterase
SANR_RS00925	COG1131	(ABC) transporter
SANR_RS00935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SANR_RS00940	COG2936	dipeptidyl-peptidase activity
SANR_RS00945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SANR_RS00950	COG2801	Transposase and inactivated derivatives
SANR_RS00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SANR_RS00990	COG1304	FMN binding
SANR_RS01000	COG3425	synthase
SANR_RS01015	COG1882	Formate acetyltransferase
SANR_RS01020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SANR_RS01035	COG0756	dUTP diphosphatase activity
SANR_RS01050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SANR_RS01055	COG3414	Phosphotransferase system galactitol-specific IIB component
SANR_RS01060	COG3775	system Galactitol-specific IIC component
SANR_RS01070	COG0235	Class ii aldolase
SANR_RS01075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SANR_RS01080	COG2171	N-acyltransferase activity
SANR_RS01085	COG1473	amidohydrolase
SANR_RS01090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SANR_RS01100	COG2226	methyltransferase
SANR_RS01105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SANR_RS01125	COG1136	(ABC) transporter
SANR_RS01125	COG0577	efflux transmembrane transporter activity
SANR_RS01130	COG0085	RNA polymerase activity
SANR_RS01135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SANR_RS01140	COG0126	phosphoglycerate kinase activity
SANR_RS01150	COG0789	Transcriptional regulator
SANR_RS01155	COG0174	glutamine synthetase
SANR_RS01165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SANR_RS01170	COG1459	type II secretion system
SANR_RS01175	COG4537	Required for transformation and DNA binding
SANR_RS01205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SANR_RS01225	COG3037	sugar-specific permease SgaT UlaA
SANR_RS01235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SANR_RS01245	COG3623	hexulose-6-phosphate isomerase
SANR_RS01265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SANR_RS01270	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
SANR_RS01280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SANR_RS01285	COG4589	Belongs to the CDS family
SANR_RS01290	COG0750	zinc metalloprotease
SANR_RS01295	COG0442	prolyl-tRNA aminoacylation
SANR_RS01305	COG0285	dihydrofolate synthase activity
SANR_RS01315	COG1363	Peptidase, m42
SANR_RS01325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SANR_RS01330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SANR_RS01345	COG4585	Histidine kinase
SANR_RS01350	COG2197	response regulator
SANR_RS01370	COG3715	PTS system
SANR_RS01375	COG3716	PTS system mannose fructose sorbose family IID component
SANR_RS01385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SANR_RS01390	COG0459	protein refolding
SANR_RS01400	COG1428	Deoxynucleoside kinase
SANR_RS01405	COG1418	mRNA catabolic process
SANR_RS01420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SANR_RS01430	COG1051	belongs to the nudix hydrolase family
SANR_RS01440	COG2264	protein methyltransferase activity
SANR_RS01445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SANR_RS01455	COG1490	D-aminoacyl-tRNA deacylase activity
SANR_RS01480	COG3590	peptidase
SANR_RS01525	COG0527	aspartate kinase activity
SANR_RS01530	COG1024	Enoyl-CoA hydratase
SANR_RS01540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SANR_RS01550	COG2070	2-Nitropropane dioxygenase
SANR_RS01555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SANR_RS01565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SANR_RS01575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SANR_RS01580	COG0439	Biotin carboxylase
SANR_RS01585	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SANR_RS01590	COG0825	malonyl-CoA metabolic process
SANR_RS01595	COG0586	Pfam SNARE associated Golgi protein
SANR_RS01610	COG3716	PTS system mannose fructose sorbose family IID component
SANR_RS01615	COG3715	PTS system
SANR_RS01625	COG1064	alcohol dehydrogenase
SANR_RS01630	COG0561	phosphatase activity
SANR_RS01640	COG2252	PERMEase
SANR_RS01645	COG0802	atpase or kinase
SANR_RS01655	COG1316	TRANSCRIPTIONal
SANR_RS01665	COG0537	adenosine 5'-monophosphoramidase activity
SANR_RS01670	COG1131	(ABC) transporter
SANR_RS01680	COG0510	thiamine kinase activity
SANR_RS01685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SANR_RS01695	COG0779	Required for maturation of 30S ribosomal subunits
SANR_RS01700	COG0195	Participates in both transcription termination and antitermination
SANR_RS01705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SANR_RS01720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SANR_RS01725	COG1283	sodium-dependent phosphate transmembrane transporter activity
SANR_RS01740	COG0752	glycyl-tRNA synthetase alpha subunit
SANR_RS01745	COG0751	glycine-tRNA ligase activity
SANR_RS01760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SANR_RS01785	COG0768	penicillin binding
SANR_RS01790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SANR_RS01795	COG4166	transmembrane transport
SANR_RS01805	COG0191	fructose-bisphosphate aldolase activity
SANR_RS01830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SANR_RS01840	COG1461	Dihydroxyacetone kinase
SANR_RS01850	COG1131	(ABC) transporter
SANR_RS01865	COG2801	Transposase and inactivated derivatives
SANR_RS01905	COG1131	(ABC) transporter
SANR_RS01930	COG1126	abc transporter atp-binding protein
SANR_RS01935	COG0765	amino acid transport
SANR_RS01945	COG1968	undecaprenyl-diphosphatase activity
SANR_RS01950	COG4862	establishment of competence for transformation
SANR_RS01955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SANR_RS01965	COG0719	Fe-S assembly protein
SANR_RS01970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SANR_RS01980	COG1686	Belongs to the peptidase S11 family
SANR_RS01985	COG0513	Belongs to the DEAD box helicase family
SANR_RS01995	COG1126	abc transporter atp-binding protein
SANR_RS02005	COG0492	ferredoxin-NADP+ reductase activity
SANR_RS02010	COG1113	amino acid transport
SANR_RS02015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SANR_RS02020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SANR_RS02025	COG3579	cysteine-type endopeptidase activity
SANR_RS02030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SANR_RS02035	COG3331	DNA recombination
SANR_RS02040	COG4474	Belongs to the UPF0398 family
SANR_RS02045	COG3599	regulation of cell shape
SANR_RS02050	COG0116	Belongs to the methyltransferase superfamily
SANR_RS02060	COG0450	alkyl hydroperoxide reductase
SANR_RS02065	COG3634	alkyl hydroperoxide reductase activity
SANR_RS02075	COG1418	mRNA catabolic process
SANR_RS02080	COG0194	GDP metabolic process
SANR_RS02085	COG1758	RNA polymerase activity
SANR_RS02090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SANR_RS02095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SANR_RS02100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SANR_RS02100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SANR_RS02105	COG0631	protein serine/threonine phosphatase activity
SANR_RS02110	COG0515	serine threonine protein kinase
SANR_RS02110	COG2815	serine threonine protein kinase
SANR_RS02120	COG4585	Histidine kinase
SANR_RS02135	COG1185	polyribonucleotide nucleotidyltransferase activity
SANR_RS02145	COG3557	Belongs to the UPF0374 family
SANR_RS02150	COG2137	regulation of response to DNA damage stimulus
SANR_RS02155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SANR_RS02165	COG2070	2-Nitropropane dioxygenase
SANR_RS02185	COG0519	Catalyzes the synthesis of GMP from XMP
SANR_RS02195	COG0525	valine-tRNA ligase activity
SANR_RS02230	COG1739	Uncharacterized protein family UPF0029
SANR_RS02235	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SANR_RS02240	COG1040	competence protein
SANR_RS02250	COG0742	ribosomal rna small subunit methyltransferase
SANR_RS02255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SANR_RS02260	COG3480	Lon protease (S16) C-terminal proteolytic domain
SANR_RS02265	COG4470	Protein conserved in bacteria
SANR_RS02285	COG2801	Transposase and inactivated derivatives
SANR_RS02315	COG1187	pseudouridine synthase activity
SANR_RS02320	COG1217	gtp-binding protein TYPA
SANR_RS02330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SANR_RS02335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SANR_RS02340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SANR_RS02350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SANR_RS02355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SANR_RS02360	COG1799	cell septum assembly
SANR_RS02375	COG3599	regulation of cell shape
SANR_RS02380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SANR_RS02385	COG1846	Transcriptional regulator
SANR_RS02395	COG0628	permease
SANR_RS02405	COG1253	flavin adenine dinucleotide binding
SANR_RS02410	COG2188	Transcriptional regulator
SANR_RS02420	COG0366	Alpha amylase catalytic
SANR_RS02430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SANR_RS02455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SANR_RS02460	COG2244	polysaccharide biosynthetic process
SANR_RS02465	COG0626	cystathionine gamma-synthase activity
SANR_RS02470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SANR_RS02475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SANR_RS02480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SANR_RS02485	COG0740	serine-type endopeptidase activity
SANR_RS02510	COG4177	L-phenylalanine transmembrane transporter activity
SANR_RS02525	COG0517	IMP dehydrogenase activity
SANR_RS02530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SANR_RS02540	COG0470	DNA polymerase III
SANR_RS02545	COG4467	Involved in initiation control of chromosome replication
SANR_RS02555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SANR_RS02560	COG1393	Belongs to the ArsC family
SANR_RS02565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SANR_RS02570	COG0708	Exodeoxyribonuclease III
SANR_RS02590	COG0640	Transcriptional regulator
SANR_RS02615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SANR_RS02615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SANR_RS02625	COG0745	RESPONSE REGULATOR receiver
SANR_RS02630	COG0642	Histidine kinase
SANR_RS02640	COG1136	(ABC) transporter
SANR_RS02645	COG0577	efflux transmembrane transporter activity
SANR_RS02650	COG0531	amino acid
SANR_RS02660	COG0456	acetyltransferase
SANR_RS02690	COG1028	Short-chain dehydrogenase reductase Sdr
SANR_RS02705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SANR_RS02720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SANR_RS02730	COG0488	(ABC) transporter
SANR_RS02735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SANR_RS02750	COG1983	PspC domain protein
SANR_RS02755	COG1674	ftsk spoiiie
SANR_RS02755	COG0697	spore germination
SANR_RS02760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SANR_RS02775	COG0081	regulation of translation
SANR_RS02780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SANR_RS02785	COG0372	Belongs to the citrate synthase family
SANR_RS02790	COG0538	isocitrate dehydrogenase activity
SANR_RS02795	COG0528	UMP kinase activity
SANR_RS02800	COG0233	cytoplasmic translational termination
SANR_RS02805	COG2996	Protein conserved in bacteria
SANR_RS02815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SANR_RS02825	COG2801	Transposase and inactivated derivatives
SANR_RS02835	COG2274	protein secretion by the type I secretion system
SANR_RS02840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SANR_RS02850	COG3290	protein histidine kinase activity
SANR_RS02925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SANR_RS02930	COG0549	Belongs to the carbamate kinase family
SANR_RS02935	COG1288	antiporter activity
SANR_RS02940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SANR_RS02950	COG1438	arginine binding
SANR_RS02955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SANR_RS02960	COG0363	glucosamine-6-phosphate deaminase activity
SANR_RS02975	COG2723	6-phospho-beta-galactosidase activity
SANR_RS02985	COG4095	Psort location CytoplasmicMembrane, score
SANR_RS02995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SANR_RS02995	COG3711	transcriptional antiterminator
SANR_RS03000	COG1447	Phosphotransferase system cellobiose-specific component IIA
SANR_RS03010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS03025	COG4122	O-methyltransferase activity
SANR_RS03030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SANR_RS03040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SANR_RS03045	COG1132	(ABC) transporter
SANR_RS03055	COG2348	transferase activity, transferring amino-acyl groups
SANR_RS03065	COG1078	dGTPase activity
SANR_RS03100	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SANR_RS03105	COG2884	Cell division ATP-binding protein ftsE
SANR_RS03110	COG2177	Part of the ABC transporter FtsEX involved in
SANR_RS03120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SANR_RS03120	COG1199	ATP-dependent helicase activity
SANR_RS03130	COG0772	Belongs to the SEDS family
SANR_RS03145	COG0187	DNA topoisomerase II activity
SANR_RS03150	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SANR_RS03155	COG2706	6-phosphogluconolactonase activity
SANR_RS03160	COG0745	RESPONSE REGULATOR receiver
SANR_RS03165	COG5002	protein histidine kinase activity
SANR_RS03165	COG3850	Histidine kinase
SANR_RS03170	COG0628	permease
SANR_RS03180	COG0028	Belongs to the TPP enzyme family
SANR_RS03185	COG3527	Alpha-acetolactate decarboxylase
SANR_RS03190	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SANR_RS03205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SANR_RS03215	COG4443	Transcriptional Coactivator p15 (PC4)
SANR_RS03220	COG4152	abc transporter atp-binding protein
SANR_RS03225	COG1668	transmembrane transport
SANR_RS03230	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SANR_RS03235	COG1074	ATP-dependent DNA helicase activity
SANR_RS03240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SANR_RS03245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SANR_RS03250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SANR_RS03255	COG0297	glycogen (starch) synthase activity
SANR_RS03260	COG0058	SHG alpha-glucan phosphorylase activity
SANR_RS03270	COG0356	it plays a direct role in the translocation of protons across the membrane
SANR_RS03275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SANR_RS03280	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SANR_RS03285	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SANR_RS03290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SANR_RS03310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SANR_RS03330	COG1132	(ABC) transporter
SANR_RS03350	COG1346	cytolysis
SANR_RS03355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SANR_RS03360	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SANR_RS03370	COG2384	SAM-dependent methyltransferase
SANR_RS03375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SANR_RS03380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SANR_RS03395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SANR_RS03405	COG1088	dTDP-glucose 4,6-dehydratase activity
SANR_RS03410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SANR_RS03445	COG0463	Glycosyl transferase, family 2
SANR_RS03450	COG1091	dTDP-4-dehydrorhamnose reductase activity
SANR_RS03495	COG1368	sulfuric ester hydrolase activity
SANR_RS03500	COG0006	proline dipeptidase activity
SANR_RS03505	COG1609	Transcriptional regulator
SANR_RS03515	COG0438	transferase activity, transferring glycosyl groups
SANR_RS03525	COG0745	RESPONSE REGULATOR receiver
SANR_RS03530	COG5002	protein histidine kinase activity
SANR_RS03535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SANR_RS03545	COG0571	ribonuclease III activity
SANR_RS03550	COG1196	nuclear chromosome segregation
SANR_RS03555	COG0561	phosphatase activity
SANR_RS03560	COG0561	phosphatase activity
SANR_RS03565	COG0552	protein localization to endoplasmic reticulum
SANR_RS03570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SANR_RS03575	COG0477	Major facilitator Superfamily
SANR_RS03580	COG3689	TIGRFAM TIGR03943 family protein
SANR_RS03585	COG0701	Predicted permease
SANR_RS03605	COG2183	response to ionizing radiation
SANR_RS03610	COG3091	SprT-like family
SANR_RS03625	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SANR_RS03630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SANR_RS03655	COG0826	peptidase U32
SANR_RS03680	COG0488	(ABC) transporter
SANR_RS03690	COG3442	glutamine amidotransferase
SANR_RS03695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SANR_RS03700	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SANR_RS03710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SANR_RS03715	COG0560	Phosphoserine phosphatase
SANR_RS03740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SANR_RS03750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SANR_RS03765	COG0726	polysaccharide deacetylase
SANR_RS03775	COG0673	inositol 2-dehydrogenase activity
SANR_RS03780	COG0572	uridine kinase
SANR_RS03790	COG2195	Cleaves the N-terminal amino acid of tripeptides
SANR_RS03795	COG0561	phosphatase activity
SANR_RS03800	COG0481	GTPase activity
SANR_RS03810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SANR_RS03815	COG3842	ATPase activity
SANR_RS03820	COG1176	ABC-type spermidine putrescine transport system, permease component I
SANR_RS03825	COG1177	transmembrane transport
SANR_RS03840	COG0574	Belongs to the PEP-utilizing enzyme family
SANR_RS03840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SANR_RS03845	COG0517	IMP dehydrogenase activity
SANR_RS03850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SANR_RS03855	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SANR_RS03860	COG1104	cysteine desulfurase activity
SANR_RS03865	COG0301	tRNA thio-modification
SANR_RS03870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SANR_RS03880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SANR_RS03890	COG0446	pyridine nucleotide-disulphide oxidoreductase
SANR_RS03905	COG1937	Protein conserved in bacteria
SANR_RS03915	COG0583	DNA-binding transcription factor activity
SANR_RS03925	COG0564	pseudouridine synthase activity
SANR_RS03930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SANR_RS03940	COG2824	Alkylphosphonate utilization operon protein PhnA
SANR_RS03960	COG0038	chloride channel
SANR_RS03965	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SANR_RS03970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SANR_RS03985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SANR_RS03990	COG1388	LysM domain
SANR_RS03990	COG1705	Flagellar rod assembly protein muramidase FlgJ
SANR_RS04000	COG1674	ftsk spoiiie
SANR_RS04050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SANR_RS04055	COG0492	ferredoxin-NADP+ reductase activity
SANR_RS04065	COG1349	DNA-binding transcription factor activity
SANR_RS04070	COG1105	Belongs to the carbohydrate kinase PfkB family
SANR_RS04075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SANR_RS04075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SANR_RS04075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SANR_RS04085	COG1307	EDD domain protein, DegV family
SANR_RS04090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SANR_RS04095	COG0617	tRNA 3'-terminal CCA addition
SANR_RS04100	COG0488	(ABC) transporter
SANR_RS04115	COG0072	phenylalanine-tRNA ligase activity
SANR_RS04115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SANR_RS04135	COG1011	Hydrolase
SANR_RS04150	COG1268	BioY protein
SANR_RS04155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SANR_RS04165	COG1136	(ABC) transporter
SANR_RS04170	COG0577	efflux transmembrane transporter activity
SANR_RS04175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SANR_RS04180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SANR_RS04200	COG0300	oxidoreductase activity
SANR_RS04215	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SANR_RS04215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SANR_RS04225	COG1131	(ABC) transporter
SANR_RS04230	COG1725	Transcriptional regulator
SANR_RS04240	COG0205	6-phosphofructokinase activity
SANR_RS04245	COG0469	pyruvate kinase activity
SANR_RS04255	COG0765	amino acid transport
SANR_RS04260	COG1126	abc transporter atp-binding protein
SANR_RS04270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SANR_RS04275	COG0210	DNA helicase
SANR_RS04285	COG2378	regulation of single-species biofilm formation
SANR_RS04290	COG1132	(ABC) transporter
SANR_RS04290	COG2375	cellular response to nickel ion
SANR_RS04295	COG1132	(ABC) transporter
SANR_RS04305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SANR_RS04310	COG0196	riboflavin kinase activity
SANR_RS04315	COG1393	Belongs to the ArsC family
SANR_RS04320	COG4476	Belongs to the UPF0223 family
SANR_RS04325	COG0483	inositol monophosphate 1-phosphatase activity
SANR_RS04330	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SANR_RS04330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SANR_RS04340	COG0573	inorganic phosphate transmembrane transporter activity
SANR_RS04345	COG0581	inorganic phosphate transmembrane transporter activity
SANR_RS04350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SANR_RS04355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SANR_RS04360	COG0704	Plays a role in the regulation of phosphate uptake
SANR_RS04365	COG2003	Belongs to the UPF0758 family
SANR_RS04370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SANR_RS04385	COG1104	cysteine desulfurase activity
SANR_RS04390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SANR_RS04400	COG2357	RelA SpoT domain protein
SANR_RS04410	COG0564	pseudouridine synthase activity
SANR_RS04415	COG0280	phosphate acetyltransferase
SANR_RS04465	COG1132	(ABC) transporter
SANR_RS04470	COG0488	(ABC) transporter
SANR_RS04490	COG0556	nucleotide-excision repair
SANR_RS04500	COG1131	(ABC) transporter
SANR_RS04510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SANR_RS04520	COG0647	UMP catabolic process
SANR_RS04540	COG1660	Displays ATPase and GTPase activities
SANR_RS04545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SANR_RS04550	COG1481	regulation of sporulation
SANR_RS04560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SANR_RS04570	COG0540	Belongs to the ATCase OTCase family
SANR_RS04575	COG0505	Belongs to the CarA family
SANR_RS04580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SANR_RS04585	COG2814	Major facilitator Superfamily
SANR_RS04590	COG0583	DNA-binding transcription factor activity
SANR_RS04615	COG0543	2 iron, 2 sulfur cluster binding
SANR_RS04620	COG0167	dihydroorotate dehydrogenase activity
SANR_RS04625	COG0284	orotidine-5'-phosphate decarboxylase activity
SANR_RS04635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SANR_RS04650	COG4479	Belongs to the UPF0346 family
SANR_RS04655	COG1702	phosphate starvation-inducible protein PhoH
SANR_RS04675	COG0686	Belongs to the AlaDH PNT family
SANR_RS04685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SANR_RS04705	COG1132	(ABC) transporter
SANR_RS04710	COG1132	(ABC) transporter
SANR_RS04715	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SANR_RS04720	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SANR_RS04725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SANR_RS04750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SANR_RS04755	COG0237	dephospho-CoA kinase activity
SANR_RS04770	COG2814	Major facilitator Superfamily
SANR_RS04780	COG0557	exoribonuclease II activity
SANR_RS04785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SANR_RS04795	COG2333	competence protein COMEC
SANR_RS04795	COG0658	competence protein
SANR_RS04810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SANR_RS04815	COG1051	belongs to the nudix hydrolase family
SANR_RS04820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SANR_RS04825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SANR_RS04830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SANR_RS04840	COG4109	DRTGG domain
SANR_RS04845	COG0024	Methionine aminopeptidase
SANR_RS04855	COG1846	Transcriptional regulator
SANR_RS04865	COG2246	polysaccharide biosynthetic process
SANR_RS04870	COG4708	membrane
SANR_RS04880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SANR_RS04885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SANR_RS04890	COG1597	lipid kinase activity
SANR_RS04895	COG1523	belongs to the glycosyl hydrolase 13 family
SANR_RS04900	COG0228	four-way junction DNA binding
SANR_RS04905	COG1837	Belongs to the UPF0109 family
SANR_RS04910	COG1827	regulation of RNA biosynthetic process
SANR_RS04925	COG3142	Participates in the control of copper homeostasis
SANR_RS04930	COG2315	Protein conserved in bacteria
SANR_RS04935	COG1132	(ABC) transporter
SANR_RS04940	COG1132	(ABC) transporter
SANR_RS04950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SANR_RS04965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SANR_RS04970	COG1970	mechanosensitive ion channel activity
SANR_RS04975	COG0358	DNA primase activity
SANR_RS04980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SANR_RS04985	COG2151	metal-sulfur cluster biosynthetic enzyme
SANR_RS04990	COG1114	Component of the transport system for branched-chain amino acids
SANR_RS04995	COG0785	Cytochrome C biogenesis protein
SANR_RS05000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SANR_RS05005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SANR_RS05005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SANR_RS05010	COG4753	response regulator
SANR_RS05010	COG2207	Transcriptional regulator
SANR_RS05015	COG2972	Histidine kinase
SANR_RS05030	COG4555	ABC transporter
SANR_RS05035	COG3976	FMN-binding domain protein
SANR_RS05035	COG1053	succinate dehydrogenase
SANR_RS05035	COG0431	NADPH-dependent FMN reductase
SANR_RS05065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SANR_RS05070	COG2233	PERMEase
SANR_RS05075	COG1942	4-Oxalocrotonate Tautomerase
SANR_RS05080	COG1435	thymidine kinase activity
SANR_RS05085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SANR_RS05090	COG2890	protein-(glutamine-N5) methyltransferase activity
SANR_RS05100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SANR_RS05110	COG0741	lytic transglycosylase activity
SANR_RS05195	COG2188	Transcriptional regulator
SANR_RS05205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SANR_RS05210	COG1136	(ABC) transporter
SANR_RS05210	COG0577	efflux transmembrane transporter activity
SANR_RS05215	COG4974	Belongs to the 'phage' integrase family
SANR_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
SANR_RS05225	COG0095	Lipoate-protein ligase
SANR_RS05230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SANR_RS05235	COG0508	dehydrogenase complex catalyzes the overall conversion of
SANR_RS05240	COG0022	dehydrogenase e1 component
SANR_RS05245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SANR_RS05265	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SANR_RS05270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SANR_RS05275	COG0758	DNA mediated transformation
SANR_RS05290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SANR_RS05295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SANR_RS05300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SANR_RS05305	COG1960	acyl-CoA dehydrogenase activity
SANR_RS05310	COG0583	DNA-binding transcription factor activity
SANR_RS05315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SANR_RS05325	COG1024	Enoyl-CoA hydratase
SANR_RS05330	COG0183	Belongs to the thiolase family
SANR_RS05335	COG1250	3-hydroxyacyl-CoA dehydrogenase
SANR_RS05340	COG1960	acyl-CoA dehydrogenase activity
SANR_RS05345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SANR_RS05350	COG3764	Sortase (surface protein transpeptidase)
SANR_RS05355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SANR_RS05360	COG0039	L-malate dehydrogenase activity
SANR_RS05375	COG0539	negative regulation of cytoplasmic translation
SANR_RS05395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SANR_RS05400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SANR_RS05425	COG0187	DNA topoisomerase II activity
SANR_RS05430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SANR_RS05435	COG0737	Belongs to the 5'-nucleotidase family
SANR_RS05440	COG2976	Protein conserved in bacteria
SANR_RS05450	COG1309	transcriptional regulator
SANR_RS05525	COG0741	lytic transglycosylase activity
SANR_RS05525	COG0791	NLP P60 protein
SANR_RS05555	COG2946	Replication initiation factor
SANR_RS05560	COG1674	ftsk spoiiie
SANR_RS05585	COG2814	Major facilitator Superfamily
SANR_RS05590	COG0017	Asparaginyl-tRNA synthetase
SANR_RS05600	COG0436	Aminotransferase
SANR_RS05610	COG1846	Transcriptional regulator
SANR_RS05615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SANR_RS05620	COG3022	response to hydroperoxide
SANR_RS05630	COG1272	protein, Hemolysin III
SANR_RS05635	COG1079	Belongs to the binding-protein-dependent transport system permease family
SANR_RS05640	COG4603	Belongs to the binding-protein-dependent transport system permease family
SANR_RS05645	COG3845	ABC transporter
SANR_RS05650	COG1744	ABC transporter substrate-binding protein PnrA-like
SANR_RS05655	COG0295	cytidine deaminase activity
SANR_RS05660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SANR_RS05670	COG2813	Specifically methylates the guanine in position
SANR_RS05675	COG1072	(Pantothenic acid kinase))
SANR_RS05680	COG0268	Binds directly to 16S ribosomal RNA
SANR_RS05690	COG4187	Peptidase family M20/M25/M40
SANR_RS05700	COG5002	protein histidine kinase activity
SANR_RS05705	COG0745	RESPONSE REGULATOR receiver
SANR_RS05730	COG1940	carbohydrate kinase activity
SANR_RS05765	COG2184	nucleotidyltransferase activity
SANR_RS05815	COG0083	homoserine kinase activity
SANR_RS05825	COG0726	polysaccharide deacetylase
SANR_RS05835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SANR_RS05845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SANR_RS05850	COG1609	Transcriptional regulator
SANR_RS05855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SANR_RS05855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SANR_RS05870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SANR_RS05875	COG1956	GAF domain-containing protein
SANR_RS05890	COG0803	Belongs to the bacterial solute-binding protein 9 family
SANR_RS05890	COG3443	Belongs to the bacterial solute-binding protein 9 family
SANR_RS05895	COG0336	Belongs to the RNA methyltransferase TrmD family
SANR_RS05900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SANR_RS05915	COG4974	Belongs to the 'phage' integrase family
SANR_RS05950	COG1937	Protein conserved in bacteria
SANR_RS05965	COG3843	relaxase mobilization nuclease domain protein
SANR_RS06000	COG0542	response to heat
SANR_RS06005	COG1396	sequence-specific DNA binding
SANR_RS06175	COG0270	DNA (cytosine-5-)-methyltransferase activity
SANR_RS06185	COG0222	ribosome binding
SANR_RS06190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SANR_RS06205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SANR_RS06220	COG1247	-acetyltransferase
SANR_RS06225	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SANR_RS06235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SANR_RS06240	COG4684	Psort location CytoplasmicMembrane, score
SANR_RS06245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SANR_RS06420	COG0740	serine-type endopeptidase activity
SANR_RS06435	COG2801	Transposase and inactivated derivatives
SANR_RS06470	COG4804	nuclease activity
SANR_RS06500	COG1129	ABC transporter
SANR_RS06515	COG1309	transcriptional regulator
SANR_RS06530	COG3177	Filamentation induced by cAMP protein fic
SANR_RS06585	COG2375	cellular response to nickel ion
SANR_RS06585	COG1132	(ABC) transporter
SANR_RS06590	COG1129	ABC transporter
SANR_RS06630	COG3433	isochorismatase activity
SANR_RS06630	COG2226	methyltransferase
SANR_RS06630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SANR_RS06635	COG1021	2,3-dihydroxybenzoate-AMP ligase
SANR_RS06650	COG1321	iron dependent repressor
SANR_RS06690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SANR_RS06690	COG0551	DNA topoisomerase type I activity
SANR_RS06710	COG1388	LysM domain
SANR_RS06710	COG0791	NLP P60 protein
SANR_RS06710	COG3103	Sh3 type 3 domain protein
SANR_RS06780	COG1475	DNA binding
SANR_RS06785	COG1192	Involved in chromosome partitioning
SANR_RS06810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SANR_RS06835	COG1132	(ABC) transporter
SANR_RS06840	COG1132	(ABC) transporter
SANR_RS06840	COG2375	cellular response to nickel ion
SANR_RS06850	COG0601	transmembrane transport
SANR_RS06855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SANR_RS06860	COG0444	Belongs to the ABC transporter superfamily
SANR_RS06870	COG0747	negative chemotaxis
SANR_RS06905	COG0551	DNA topoisomerase type I activity
SANR_RS06905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SANR_RS06910	COG3344	reverse transcriptase
SANR_RS06965	COG4804	nuclease activity
SANR_RS07030	COG1484	DNA-dependent DNA replication
SANR_RS07045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SANR_RS07055	COG0077	Prephenate dehydratase
SANR_RS07060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SANR_RS07065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SANR_RS07075	COG3679	Belongs to the UPF0342 family
SANR_RS07080	COG0287	Prephenate dehydrogenase
SANR_RS07090	COG0730	response to heat
SANR_RS07095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SANR_RS07100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SANR_RS07105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SANR_RS07110	COG0710	3-dehydroquinate dehydratase activity
SANR_RS07115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SANR_RS07120	COG1368	sulfuric ester hydrolase activity
SANR_RS07130	COG0813	purine-nucleoside phosphorylase activity
SANR_RS07140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SANR_RS07145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SANR_RS07160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SANR_RS07190	COG3843	relaxase mobilization nuclease domain protein
SANR_RS07240	COG3942	CHAP domain
SANR_RS07240	COG1388	LysM domain
SANR_RS07315	COG1595	DNA-templated transcription, initiation
SANR_RS07320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SANR_RS07325	COG0772	Belongs to the SEDS family
SANR_RS07340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SANR_RS07345	COG0406	alpha-ribazole phosphatase activity
SANR_RS07350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SANR_RS07380	COG1882	Formate acetyltransferase
SANR_RS07385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS07395	COG1447	Phosphotransferase system cellobiose-specific component IIA
SANR_RS07405	COG1349	DNA-binding transcription factor activity
SANR_RS07410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SANR_RS07415	COG1959	2 iron, 2 sulfur cluster binding
SANR_RS07430	COG1136	(ABC) transporter
SANR_RS07435	COG1309	transcriptional regulator
SANR_RS07455	COG0716	FMN binding
SANR_RS07460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SANR_RS07465	COG0254	rRNA binding
SANR_RS07470	COG4974	Belongs to the 'phage' integrase family
SANR_RS07535	COG1125	glycine betaine transport
SANR_RS07540	COG1174	glycine betaine transport
SANR_RS07555	COG1573	uracil-dna glycosylase
SANR_RS07565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SANR_RS07595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SANR_RS07605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SANR_RS07615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SANR_RS07635	COG1476	TRANSCRIPTIONal
SANR_RS07650	COG0204	Acyl-transferase
SANR_RS07655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SANR_RS07660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SANR_RS07665	COG2827	Endonuclease containing a URI domain
SANR_RS07670	COG1755	Isoprenylcysteine carboxyl methyltransferase
SANR_RS07675	COG2723	6-phospho-beta-galactosidase activity
SANR_RS07680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS07680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS07685	COG1447	Phosphotransferase system cellobiose-specific component IIA
SANR_RS07690	COG3711	transcriptional antiterminator
SANR_RS07715	COG3775	system Galactitol-specific IIC component
SANR_RS07735	COG0698	ribose 5-phosphate isomerase
SANR_RS07740	COG1349	DNA-binding transcription factor activity
SANR_RS07750	COG0513	Belongs to the DEAD box helicase family
SANR_RS07770	COG3620	sequence-specific DNA binding
SANR_RS07790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SANR_RS07795	COG1181	Belongs to the D-alanine--D-alanine ligase family
SANR_RS07800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SANR_RS07805	COG0768	penicillin binding
SANR_RS07810	COG0588	phosphoglycerate mutase activity
SANR_RS07825	COG1307	EDD domain protein, DegV family
SANR_RS07830	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SANR_RS07835	COG4605	iron ion homeostasis
SANR_RS07840	COG4604	ABC transporter, ATP-binding protein
SANR_RS07845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SANR_RS07850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SANR_RS07855	COG0497	DNA recombination
SANR_RS07860	COG1438	arginine binding
SANR_RS07865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SANR_RS07875	COG1722	exodeoxyribonuclease VII activity
SANR_RS07880	COG1570	exodeoxyribonuclease VII activity
SANR_RS07895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SANR_RS07900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SANR_RS07905	COG0577	efflux transmembrane transporter activity
SANR_RS07910	COG1136	(ABC) transporter
SANR_RS07935	COG2801	Transposase and inactivated derivatives
SANR_RS07950	COG4703	Protein of unknown function (DUF1797)
SANR_RS07955	COG0542	response to heat
SANR_RS07965	COG0494	nUDIX hydrolase
SANR_RS07975	COG0025	NhaP-type Na H and K H
SANR_RS07985	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SANR_RS07990	COG1242	4 iron, 4 sulfur cluster binding
SANR_RS08000	COG0671	phosphoesterase, PA-phosphatase related
SANR_RS08005	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SANR_RS08015	COG0569	domain protein
SANR_RS08035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SANR_RS08040	COG1187	pseudouridine synthase activity
SANR_RS08045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SANR_RS08050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SANR_RS08055	COG4974	Belongs to the 'phage' integrase family
SANR_RS08070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SANR_RS08075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SANR_RS08100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SANR_RS08105	COG1254	Belongs to the acylphosphatase family
SANR_RS08140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SANR_RS08155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SANR_RS08165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SANR_RS08175	COG1160	GTP binding
SANR_RS08185	COG1484	DNA-dependent DNA replication
SANR_RS08195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SANR_RS08210	COG2190	(PTS) system
SANR_RS08210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS08210	COG1263	PTS System
SANR_RS08215	COG0745	RESPONSE REGULATOR receiver
SANR_RS08220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SANR_RS08235	COG0501	Belongs to the peptidase M48B family
SANR_RS08240	COG1704	LemA family
SANR_RS08245	COG0357	Ribosomal RNA small subunit methyltransferase G
SANR_RS08250	COG1442	glycosyl transferase family 8
SANR_RS08255	COG4221	oxidoreductase activity
SANR_RS08265	COG1122	ATPase activity
SANR_RS08295	COG2801	Transposase and inactivated derivatives
SANR_RS08300	COG4720	Psort location CytoplasmicMembrane, score
SANR_RS08385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SANR_RS08390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SANR_RS08395	COG1464	Belongs to the NlpA lipoprotein family
SANR_RS08400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SANR_RS08410	COG1396	sequence-specific DNA binding
SANR_RS08415	COG0217	transcriptional regulatory protein
SANR_RS08420	COG1323	Belongs to the UPF0348 family
SANR_RS08440	COG2226	methyltransferase
SANR_RS08445	COG0799	negative regulation of ribosome biogenesis
SANR_RS08450	COG1335	isochorismatase
SANR_RS08455	COG1713	HD superfamily hydrolase involved in NAD metabolism
SANR_RS08460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SANR_RS08465	COG1534	Rna-binding protein
SANR_RS08470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SANR_RS08475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SANR_RS08490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SANR_RS08495	COG0154	amidase activity
SANR_RS08500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SANR_RS08505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SANR_RS08510	COG1335	isochorismatase
SANR_RS08515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SANR_RS08520	COG0436	Aminotransferase
SANR_RS08525	COG0589	response to stress
SANR_RS08530	COG0561	phosphatase activity
SANR_RS08535	COG0252	asparaginase activity
SANR_RS08540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SANR_RS08545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SANR_RS08550	COG0736	holo-[acyl-carrier-protein] synthase activity
SANR_RS08555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SANR_RS08565	COG0531	amino acid
SANR_RS08570	COG1482	cell wall glycoprotein biosynthetic process
SANR_RS08575	COG2188	Transcriptional regulator
SANR_RS08580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS08585	COG2723	6-phospho-beta-galactosidase activity
SANR_RS08590	COG1447	Phosphotransferase system cellobiose-specific component IIA
SANR_RS08595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS08600	COG1132	(ABC) transporter
SANR_RS08615	COG0242	peptide deformylase activity
SANR_RS08620	COG1940	carbohydrate kinase activity
SANR_RS08625	COG1263	PTS System
SANR_RS08625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS08625	COG2190	(PTS) system
SANR_RS08630	COG1621	beta-fructofuranosidase activity
SANR_RS08635	COG1609	Transcriptional regulator
SANR_RS08640	COG0561	phosphatase activity
SANR_RS08645	COG4608	Belongs to the ABC transporter superfamily
SANR_RS08650	COG0444	Belongs to the ABC transporter superfamily
SANR_RS08655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SANR_RS08660	COG0601	transmembrane transport
SANR_RS08665	COG4166	transmembrane transport
SANR_RS08670	COG4166	transmembrane transport
SANR_RS08680	COG0504	CTP synthase activity
SANR_RS08685	COG3343	RNA polymerase activity
SANR_RS08690	COG0544	peptidyl-prolyl cis-trans isomerase activity
SANR_RS08695	COG4475	Protein of unknown function (DUF436)
SANR_RS08700	COG4720	Psort location CytoplasmicMembrane, score
SANR_RS08705	COG0351	phosphomethylpyrimidine kinase
SANR_RS08710	COG0101	tRNA pseudouridine synthase activity
SANR_RS08720	COG0484	heat shock protein binding
SANR_RS08730	COG0443	Heat shock 70 kDa protein
SANR_RS08735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SANR_RS08740	COG1420	regulation of RNA biosynthetic process
SANR_RS08745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SANR_RS08750	COG3037	sugar-specific permease SgaT UlaA
SANR_RS08760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SANR_RS08765	COG0588	phosphoglycerate mutase activity
SANR_RS08770	COG0588	phosphoglycerate mutase activity
SANR_RS08775	COG2848	UPF0210 protein
SANR_RS08780	COG3830	Belongs to the UPF0237 family
SANR_RS08785	COG1609	Transcriptional regulator
SANR_RS08800	COG3716	PTS system mannose fructose sorbose family IID component
SANR_RS08805	COG3715	PTS system
SANR_RS08810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS08815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SANR_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
SANR_RS08850	COG5492	domain, Protein
SANR_RS08860	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SANR_RS08875	COG2801	Transposase and inactivated derivatives
SANR_RS08960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SANR_RS08965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SANR_RS08975	COG3688	RNA-binding protein containing a PIN domain
SANR_RS08985	COG3842	ATPase activity
SANR_RS08995	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SANR_RS09000	COG0215	cysteine-tRNA ligase activity
SANR_RS09010	COG1045	serine acetyltransferase
SANR_RS09015	COG1185	polyribonucleotide nucleotidyltransferase activity
SANR_RS09020	COG1164	Oligoendopeptidase f
SANR_RS09035	COG3118	belongs to the thioredoxin family
SANR_RS09050	COG1187	pseudouridine synthase activity
SANR_RS09085	COG0438	transferase activity, transferring glycosyl groups
SANR_RS09115	COG0242	peptide deformylase activity
SANR_RS09130	COG2176	DNA-directed DNA polymerase activity
SANR_RS09135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SANR_RS09140	COG1523	belongs to the glycosyl hydrolase 13 family
SANR_RS09155	COG2249	NAD(P)H dehydrogenase (quinone) activity
SANR_RS09190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SANR_RS09195	COG0006	proline dipeptidase activity
SANR_RS09205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SANR_RS09220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SANR_RS09225	COG0629	single-stranded DNA binding
SANR_RS09250	COG0588	phosphoglycerate mutase activity
SANR_RS09275	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SANR_RS09285	COG1122	ATPase activity
SANR_RS09310	COG5002	protein histidine kinase activity
SANR_RS09315	COG0745	RESPONSE REGULATOR receiver
SANR_RS09320	COG2723	6-phospho-beta-galactosidase activity
SANR_RS09325	COG1304	FMN binding
SANR_RS09330	COG0028	Belongs to the TPP enzyme family
SANR_RS09335	COG1876	peptidase activity
SANR_RS09355	COG3290	protein histidine kinase activity
SANR_RS09380	COG0561	phosphatase activity
SANR_RS09390	COG0346	lactoylglutathione lyase activity
SANR_RS09415	COG2190	(PTS) system
SANR_RS09415	COG1263	PTS System
SANR_RS09415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SANR_RS09420	COG1447	Phosphotransferase system cellobiose-specific component IIA
SANR_RS09425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS09435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SANR_RS09440	COG1940	carbohydrate kinase activity
SANR_RS09455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SANR_RS09455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SANR_RS09460	COG0167	dihydroorotate dehydrogenase activity
SANR_RS09465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SANR_RS09475	COG0668	transmembrane transport
SANR_RS09480	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SANR_RS09555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SANR_RS09555	COG0551	DNA topoisomerase type I activity
SANR_RS09625	COG1484	DNA-dependent DNA replication
SANR_RS09645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SANR_RS09650	COG3118	belongs to the thioredoxin family
SANR_RS09660	COG1193	negative regulation of DNA recombination
SANR_RS09680	COG0681	Belongs to the peptidase S26 family
SANR_RS09690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SANR_RS09715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SANR_RS09720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SANR_RS09745	COG1214	PFAM Peptidase M22, glycoprotease
SANR_RS09765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SANR_RS09770	COG0049	tRNA binding
SANR_RS09775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SANR_RS09785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SANR_RS09790	COG3481	metal-dependent phosphohydrolase, HD sub domain
SANR_RS09800	COG1564	THIamine pyrophosphokinase
SANR_RS09810	COG1162	GTPase activity
SANR_RS09825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SANR_RS09845	COG0084	hydrolase, TatD family'
SANR_RS09850	COG0582	viral genome integration into host DNA
SANR_RS09890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SANR_RS09910	COG0594	ribonuclease P activity
SANR_RS09920	COG0166	Belongs to the GPI family
SANR_RS09950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SANR_RS09970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SANR_RS09975	COG0789	Transcriptional regulator
SANR_RS09980	COG1063	alcohol dehydrogenase
SANR_RS09995	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SANR_RS10000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SANR_RS10015	COG4463	regulation of RNA biosynthetic process
SANR_RS10025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SANR_RS10030	COG0052	Belongs to the universal ribosomal protein uS2 family
SANR_RS10040	COG0203	ribosomal protein L17
SANR_RS10045	COG0202	RNA polymerase activity
SANR_RS10050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SANR_RS10055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SANR_RS10060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SANR_RS10065	COG0563	adenylate kinase activity
SANR_RS10070	COG0201	protein transport
SANR_RS10075	COG0200	Binds to the 23S rRNA
SANR_RS10080	COG1841	ribosomal large subunit assembly
SANR_RS10085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SANR_RS10095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SANR_RS10100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SANR_RS10105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SANR_RS10110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SANR_RS10115	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SANR_RS10120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SANR_RS10130	COG0255	Belongs to the universal ribosomal protein uL29 family
SANR_RS10135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SANR_RS10140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SANR_RS10145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SANR_RS10155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SANR_RS10160	COG0089	rRNA binding
SANR_RS10165	COG0088	Forms part of the polypeptide exit tunnel
SANR_RS10170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SANR_RS10175	COG0051	transcription antitermination factor activity, RNA binding
SANR_RS10190	COG0343	queuine tRNA-ribosyltransferase activity
SANR_RS10205	COG1832	CoA-binding protein
SANR_RS10210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SANR_RS10210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SANR_RS10230	COG5002	protein histidine kinase activity
SANR_RS10305	COG0602	queuosine metabolic process
SANR_RS10325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SANR_RS10335	COG0285	dihydrofolate synthase activity
SANR_RS10340	COG3906	Belongs to the UPF0473 family
SANR_RS10345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SANR_RS10350	COG4472	Bacterial protein of unknown function (DUF965)
SANR_RS10365	COG1393	Belongs to the ArsC family
SANR_RS10370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SANR_RS10375	COG1058	Belongs to the CinA family
SANR_RS10375	COG1546	Belongs to the CinA family
SANR_RS10385	COG0519	Catalyzes the synthesis of GMP from XMP
SANR_RS10390	COG0632	four-way junction helicase activity
SANR_RS10400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SANR_RS10405	COG0582	viral genome integration into host DNA
SANR_RS10490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SANR_RS10495	COG1438	arginine binding
SANR_RS10500	COG0018	arginyl-trna synthetase
SANR_RS10505	COG1780	Probably involved in ribonucleotide reductase function
SANR_RS10515	COG0058	SHG alpha-glucan phosphorylase activity
SANR_RS10520	COG1640	4-alpha-glucanotransferase
SANR_RS10525	COG2182	Extracellular solute-binding protein
SANR_RS10530	COG1175	transmembrane transport
SANR_RS10535	COG3833	ABC-type maltose transport systems, permease component
SANR_RS10540	COG5521	maltodextrose utilization protein MalA
SANR_RS10545	COG1609	Transcriptional regulator
SANR_RS10550	COG1523	belongs to the glycosyl hydrolase 13 family
SANR_RS10555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SANR_RS10575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SANR_RS10580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SANR_RS10635	COG0582	viral genome integration into host DNA
SANR_RS10650	COG2807	transmembrane transport
SANR_RS10655	COG2094	Belongs to the DNA glycosylase MPG family
SANR_RS10660	COG0561	phosphatase activity
SANR_RS10665	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SANR_RS10670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SANR_RS10675	COG1696	Membrane protein involved in D-alanine export
SANR_RS10740	COG0561	phosphatase activity
SANR_RS10760	COG1011	Hydrolase
SANR_RS10770	COG0305	Participates in initiation and elongation during chromosome replication
SANR_RS10785	COG0445	tRNA wobble uridine modification
SANR_RS10790	COG0482	sulfurtransferase activity
SANR_RS10800	COG1760	l-serine dehydratase
SANR_RS10805	COG1760	l-serine dehydratase
SANR_RS10820	COG2801	Transposase and inactivated derivatives
SANR_RS10830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SANR_RS10835	COG1122	ATPase activity
SANR_RS10840	COG1122	ATPase activity
SANR_RS10845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SANR_RS10855	COG0612	Peptidase, M16
SANR_RS10860	COG0612	Peptidase, M16
SANR_RS10870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SANR_RS10875	COG0516	GMP reductase activity
SANR_RS10875	COG0517	IMP dehydrogenase activity
SANR_RS10880	COG0180	Tryptophanyl-tRNA synthetase
SANR_RS10885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SANR_RS10890	COG0149	triose-phosphate isomerase activity
SANR_RS10900	COG0488	(ABC) transporter
SANR_RS10940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SANR_RS10945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SANR_RS10950	COG1475	DNA binding
SANR_RS10980	COG0582	viral genome integration into host DNA