locus-tag	class	description
ANG_RS00025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANG_RS00030	COG0564	pseudouridine synthase activity
ANG_RS00050	COG3443	Belongs to the bacterial solute-binding protein 9 family
ANG_RS00050	COG0803	Belongs to the bacterial solute-binding protein 9 family
ANG_RS00055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANG_RS00060	COG1121	(ABC) transporter
ANG_RS00065	COG1846	Transcriptional regulator
ANG_RS00095	COG1914	H( )-stimulated, divalent metal cation uptake system
ANG_RS00100	COG3759	membrane
ANG_RS00120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANG_RS00125	COG1394	ATPase activity, coupled to movement of substances
ANG_RS00130	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ANG_RS00135	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ANG_RS00145	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
ANG_RS00150	COG1527	subunit (C
ANG_RS00160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANG_RS00165	COG1269	ATP hydrolysis coupled proton transport
ANG_RS00180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ANG_RS00185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS00185	COG1263	PTS System
ANG_RS00205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANG_RS00220	COG0395	ABC-type sugar transport system, permease component
ANG_RS00225	COG1175	transmembrane transport
ANG_RS00235	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ANG_RS00240	COG1454	alcohol dehydrogenase
ANG_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
ANG_RS00255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANG_RS00265	COG2255	four-way junction helicase activity
ANG_RS00270	COG2801	Transposase and inactivated derivatives
ANG_RS00285	COG3684	Belongs to the aldolase LacD family
ANG_RS00290	COG2222	sugar isomerase
ANG_RS00300	COG3716	PTS system mannose fructose sorbose family IID component
ANG_RS00310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS00330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ANG_RS00335	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ANG_RS00340	COG1461	Dihydroxyacetone kinase
ANG_RS00345	COG2376	Dihydroxyacetone kinase
ANG_RS00355	COG2376	Dihydroxyacetone kinase
ANG_RS00360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANG_RS00380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ANG_RS00385	COG1683	Conserved Protein
ANG_RS00395	COG3942	CHAP domain
ANG_RS00410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANG_RS00415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ANG_RS00430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ANG_RS00435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANG_RS00445	COG1381	Involved in DNA repair and RecF pathway recombination
ANG_RS00450	COG0436	Aminotransferase
ANG_RS00455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ANG_RS00460	COG3942	CHAP domain
ANG_RS00470	COG1792	Involved in formation and maintenance of cell shape
ANG_RS00595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANG_RS00600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ANG_RS00605	COG0037	tRNA processing
ANG_RS00620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANG_RS00625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANG_RS00630	COG0193	aminoacyl-tRNA hydrolase activity
ANG_RS00635	COG0012	GTP binding
ANG_RS00650	COG0592	DNA-directed DNA polymerase activity
ANG_RS00660	COG1475	DNA binding
ANG_RS00665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANG_RS00670	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ANG_RS00710	COG0488	(ABC) transporter
ANG_RS00720	COG0149	triose-phosphate isomerase activity
ANG_RS00725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANG_RS00730	COG0180	Tryptophanyl-tRNA synthetase
ANG_RS00735	COG0516	GMP reductase activity
ANG_RS00735	COG0517	IMP dehydrogenase activity
ANG_RS00740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANG_RS00755	COG0612	Peptidase, M16
ANG_RS00765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANG_RS00770	COG1122	ATPase activity
ANG_RS00775	COG1122	ATPase activity
ANG_RS00780	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ANG_RS00790	COG2801	Transposase and inactivated derivatives
ANG_RS00805	COG1760	l-serine dehydratase
ANG_RS00810	COG1760	l-serine dehydratase
ANG_RS00820	COG0482	sulfurtransferase activity
ANG_RS00825	COG0445	tRNA wobble uridine modification
ANG_RS00840	COG0305	Participates in initiation and elongation during chromosome replication
ANG_RS00850	COG1011	Hydrolase
ANG_RS00870	COG0561	phosphatase activity
ANG_RS00935	COG1696	Membrane protein involved in D-alanine export
ANG_RS00940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANG_RS00945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ANG_RS00950	COG0561	phosphatase activity
ANG_RS00955	COG2094	Belongs to the DNA glycosylase MPG family
ANG_RS00960	COG2807	transmembrane transport
ANG_RS00975	COG0582	viral genome integration into host DNA
ANG_RS00990	COG1674	ftsk spoiiie
ANG_RS01025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ANG_RS01030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANG_RS01050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ANG_RS01055	COG1523	belongs to the glycosyl hydrolase 13 family
ANG_RS01060	COG1609	Transcriptional regulator
ANG_RS01065	COG5521	maltodextrose utilization protein MalA
ANG_RS01070	COG3833	ABC-type maltose transport systems, permease component
ANG_RS01075	COG1175	transmembrane transport
ANG_RS01080	COG2182	Extracellular solute-binding protein
ANG_RS01085	COG1640	4-alpha-glucanotransferase
ANG_RS01090	COG0058	SHG alpha-glucan phosphorylase activity
ANG_RS01100	COG1780	Probably involved in ribonucleotide reductase function
ANG_RS01105	COG0018	arginyl-trna synthetase
ANG_RS01110	COG1438	arginine binding
ANG_RS01115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANG_RS01195	COG0582	viral genome integration into host DNA
ANG_RS01200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ANG_RS01210	COG0632	four-way junction helicase activity
ANG_RS01215	COG0519	Catalyzes the synthesis of GMP from XMP
ANG_RS01225	COG1058	Belongs to the CinA family
ANG_RS01225	COG1546	Belongs to the CinA family
ANG_RS01230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANG_RS01235	COG1393	Belongs to the ArsC family
ANG_RS01250	COG4472	Bacterial protein of unknown function (DUF965)
ANG_RS01255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ANG_RS01260	COG3906	Belongs to the UPF0473 family
ANG_RS01265	COG0285	dihydrofolate synthase activity
ANG_RS01275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANG_RS01295	COG0602	queuosine metabolic process
ANG_RS01370	COG5002	protein histidine kinase activity
ANG_RS01390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANG_RS01390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANG_RS01395	COG1832	CoA-binding protein
ANG_RS01410	COG0343	queuine tRNA-ribosyltransferase activity
ANG_RS01425	COG0051	transcription antitermination factor activity, RNA binding
ANG_RS01430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANG_RS01435	COG0088	Forms part of the polypeptide exit tunnel
ANG_RS01440	COG0089	rRNA binding
ANG_RS01445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANG_RS01455	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANG_RS01460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANG_RS01465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANG_RS01470	COG0255	Belongs to the universal ribosomal protein uL29 family
ANG_RS01480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ANG_RS01485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ANG_RS01490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANG_RS01495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ANG_RS01500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANG_RS01505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ANG_RS01515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ANG_RS01520	COG1841	ribosomal large subunit assembly
ANG_RS01525	COG0200	Binds to the 23S rRNA
ANG_RS01530	COG0201	protein transport
ANG_RS01535	COG0563	adenylate kinase activity
ANG_RS01540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANG_RS01545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ANG_RS01550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANG_RS01555	COG0202	RNA polymerase activity
ANG_RS01560	COG0203	ribosomal protein L17
ANG_RS01570	COG0052	Belongs to the universal ribosomal protein uS2 family
ANG_RS01575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANG_RS01585	COG4463	regulation of RNA biosynthetic process
ANG_RS01600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANG_RS01605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANG_RS01620	COG1063	alcohol dehydrogenase
ANG_RS01625	COG0789	Transcriptional regulator
ANG_RS01630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANG_RS01650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ANG_RS01680	COG0166	Belongs to the GPI family
ANG_RS01690	COG0594	ribonuclease P activity
ANG_RS01710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ANG_RS01750	COG0582	viral genome integration into host DNA
ANG_RS01755	COG0084	hydrolase, TatD family'
ANG_RS01775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANG_RS01790	COG1162	GTPase activity
ANG_RS01800	COG1564	THIamine pyrophosphokinase
ANG_RS01810	COG3481	metal-dependent phosphohydrolase, HD sub domain
ANG_RS01815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANG_RS01825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANG_RS01830	COG0049	tRNA binding
ANG_RS01835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANG_RS01855	COG1214	PFAM Peptidase M22, glycoprotease
ANG_RS01880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ANG_RS01885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ANG_RS01910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANG_RS01920	COG0681	Belongs to the peptidase S26 family
ANG_RS01940	COG1193	negative regulation of DNA recombination
ANG_RS01950	COG3118	belongs to the thioredoxin family
ANG_RS01955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANG_RS01975	COG1484	DNA-dependent DNA replication
ANG_RS01995	COG1309	transcriptional regulator
ANG_RS02010	COG1129	ABC transporter
ANG_RS02040	COG4804	nuclease activity
ANG_RS02110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANG_RS02110	COG0551	DNA topoisomerase type I activity
ANG_RS02125	COG3843	relaxase mobilization nuclease domain protein
ANG_RS02160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ANG_RS02165	COG0668	transmembrane transport
ANG_RS02175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANG_RS02180	COG0167	dihydroorotate dehydrogenase activity
ANG_RS02185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANG_RS02185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANG_RS02200	COG1940	carbohydrate kinase activity
ANG_RS02205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS02215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS02220	COG1447	Phosphotransferase system cellobiose-specific component IIA
ANG_RS02240	COG1917	Cupin 2, conserved barrel domain protein
ANG_RS02240	COG2207	Transcriptional regulator
ANG_RS02250	COG0346	lactoylglutathione lyase activity
ANG_RS02260	COG0561	phosphatase activity
ANG_RS02285	COG3290	protein histidine kinase activity
ANG_RS02305	COG1876	peptidase activity
ANG_RS02310	COG0028	Belongs to the TPP enzyme family
ANG_RS02315	COG1304	FMN binding
ANG_RS02320	COG2723	6-phospho-beta-galactosidase activity
ANG_RS02325	COG0745	RESPONSE REGULATOR receiver
ANG_RS02330	COG5002	protein histidine kinase activity
ANG_RS02355	COG1122	ATPase activity
ANG_RS02365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ANG_RS02390	COG0588	phosphoglycerate mutase activity
ANG_RS02415	COG0629	single-stranded DNA binding
ANG_RS02420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ANG_RS02435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANG_RS02445	COG0006	proline dipeptidase activity
ANG_RS02450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ANG_RS02485	COG2249	NAD(P)H dehydrogenase (quinone) activity
ANG_RS02500	COG1523	belongs to the glycosyl hydrolase 13 family
ANG_RS02505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ANG_RS02510	COG2176	DNA-directed DNA polymerase activity
ANG_RS02525	COG0242	peptide deformylase activity
ANG_RS02545	COG0438	transferase activity, transferring glycosyl groups
ANG_RS02580	COG1187	pseudouridine synthase activity
ANG_RS02595	COG3118	belongs to the thioredoxin family
ANG_RS02610	COG1164	Oligoendopeptidase f
ANG_RS02615	COG1185	polyribonucleotide nucleotidyltransferase activity
ANG_RS02620	COG1045	serine acetyltransferase
ANG_RS02630	COG0215	cysteine-tRNA ligase activity
ANG_RS02635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ANG_RS02645	COG3842	ATPase activity
ANG_RS02655	COG3688	RNA-binding protein containing a PIN domain
ANG_RS02665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANG_RS02670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ANG_RS02755	COG2801	Transposase and inactivated derivatives
ANG_RS02770	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ANG_RS02780	COG5492	domain, Protein
ANG_RS02805	COG1028	Short-chain dehydrogenase reductase Sdr
ANG_RS02815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ANG_RS02820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS02825	COG3715	PTS system
ANG_RS02830	COG3716	PTS system mannose fructose sorbose family IID component
ANG_RS02845	COG1609	Transcriptional regulator
ANG_RS02850	COG3830	Belongs to the UPF0237 family
ANG_RS02855	COG2848	UPF0210 protein
ANG_RS02860	COG0588	phosphoglycerate mutase activity
ANG_RS02865	COG0588	phosphoglycerate mutase activity
ANG_RS02870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANG_RS02880	COG3037	sugar-specific permease SgaT UlaA
ANG_RS02885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANG_RS02890	COG1420	regulation of RNA biosynthetic process
ANG_RS02895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANG_RS02900	COG0443	Heat shock 70 kDa protein
ANG_RS02910	COG0484	heat shock protein binding
ANG_RS02920	COG0101	tRNA pseudouridine synthase activity
ANG_RS02925	COG0351	phosphomethylpyrimidine kinase
ANG_RS02930	COG4720	Psort location CytoplasmicMembrane, score
ANG_RS02935	COG4475	Protein of unknown function (DUF436)
ANG_RS02940	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANG_RS02945	COG3343	RNA polymerase activity
ANG_RS02950	COG0504	CTP synthase activity
ANG_RS02960	COG4166	transmembrane transport
ANG_RS02965	COG4166	transmembrane transport
ANG_RS02970	COG0601	transmembrane transport
ANG_RS02975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANG_RS02980	COG0444	Belongs to the ABC transporter superfamily
ANG_RS02985	COG4608	Belongs to the ABC transporter superfamily
ANG_RS02995	COG1609	Transcriptional regulator
ANG_RS03000	COG1621	beta-fructofuranosidase activity
ANG_RS03005	COG1263	PTS System
ANG_RS03005	COG2190	(PTS) system
ANG_RS03005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS03010	COG1940	carbohydrate kinase activity
ANG_RS03015	COG0242	peptide deformylase activity
ANG_RS03030	COG1132	(ABC) transporter
ANG_RS03035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS03040	COG1447	Phosphotransferase system cellobiose-specific component IIA
ANG_RS03045	COG2723	6-phospho-beta-galactosidase activity
ANG_RS03050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS03055	COG2188	Transcriptional regulator
ANG_RS03060	COG1482	cell wall glycoprotein biosynthetic process
ANG_RS03065	COG0531	amino acid
ANG_RS03075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANG_RS03080	COG0736	holo-[acyl-carrier-protein] synthase activity
ANG_RS03085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANG_RS03090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ANG_RS03095	COG0252	asparaginase activity
ANG_RS03100	COG0561	phosphatase activity
ANG_RS03105	COG0589	response to stress
ANG_RS03110	COG0436	Aminotransferase
ANG_RS03115	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ANG_RS03120	COG1335	isochorismatase
ANG_RS03125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANG_RS03130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANG_RS03135	COG0154	amidase activity
ANG_RS03140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANG_RS03155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ANG_RS03160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ANG_RS03165	COG1534	Rna-binding protein
ANG_RS03170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ANG_RS03175	COG1713	HD superfamily hydrolase involved in NAD metabolism
ANG_RS03180	COG1335	isochorismatase
ANG_RS03185	COG0799	negative regulation of ribosome biogenesis
ANG_RS03190	COG2226	methyltransferase
ANG_RS03210	COG1323	Belongs to the UPF0348 family
ANG_RS03215	COG0217	transcriptional regulatory protein
ANG_RS03220	COG1396	sequence-specific DNA binding
ANG_RS03230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANG_RS03235	COG1464	Belongs to the NlpA lipoprotein family
ANG_RS03240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANG_RS03245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANG_RS03330	COG4720	Psort location CytoplasmicMembrane, score
ANG_RS03335	COG2801	Transposase and inactivated derivatives
ANG_RS03365	COG1122	ATPase activity
ANG_RS03375	COG4221	oxidoreductase activity
ANG_RS03380	COG1442	glycosyl transferase family 8
ANG_RS03385	COG0357	Ribosomal RNA small subunit methyltransferase G
ANG_RS03390	COG1704	LemA family
ANG_RS03395	COG0501	Belongs to the peptidase M48B family
ANG_RS03410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ANG_RS03415	COG0745	RESPONSE REGULATOR receiver
ANG_RS03420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS03420	COG2190	(PTS) system
ANG_RS03420	COG1263	PTS System
ANG_RS03435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANG_RS03445	COG1484	DNA-dependent DNA replication
ANG_RS03455	COG1160	GTP binding
ANG_RS03465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANG_RS03475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANG_RS03490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANG_RS03525	COG1254	Belongs to the acylphosphatase family
ANG_RS03530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANG_RS03555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANG_RS03560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANG_RS03575	COG4974	Belongs to the 'phage' integrase family
ANG_RS03580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ANG_RS03585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ANG_RS03590	COG1187	pseudouridine synthase activity
ANG_RS03595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ANG_RS03615	COG0569	domain protein
ANG_RS03625	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ANG_RS03630	COG0671	phosphoesterase, PA-phosphatase related
ANG_RS03640	COG1242	4 iron, 4 sulfur cluster binding
ANG_RS03645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ANG_RS03655	COG0025	NhaP-type Na H and K H
ANG_RS03665	COG0494	nUDIX hydrolase
ANG_RS03675	COG0542	response to heat
ANG_RS03680	COG4703	Protein of unknown function (DUF1797)
ANG_RS03695	COG2801	Transposase and inactivated derivatives
ANG_RS03720	COG1136	(ABC) transporter
ANG_RS03725	COG0577	efflux transmembrane transporter activity
ANG_RS03730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ANG_RS03735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ANG_RS03750	COG1570	exodeoxyribonuclease VII activity
ANG_RS03755	COG1722	exodeoxyribonuclease VII activity
ANG_RS03765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ANG_RS03770	COG1438	arginine binding
ANG_RS03775	COG0497	DNA recombination
ANG_RS03780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANG_RS03785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANG_RS03790	COG4604	ABC transporter, ATP-binding protein
ANG_RS03795	COG4605	iron ion homeostasis
ANG_RS03800	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANG_RS03805	COG1307	EDD domain protein, DegV family
ANG_RS03820	COG0588	phosphoglycerate mutase activity
ANG_RS03825	COG0768	penicillin binding
ANG_RS03830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANG_RS03835	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANG_RS03840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANG_RS03860	COG3620	sequence-specific DNA binding
ANG_RS03880	COG0513	Belongs to the DEAD box helicase family
ANG_RS03890	COG1349	DNA-binding transcription factor activity
ANG_RS03895	COG0698	ribose 5-phosphate isomerase
ANG_RS03915	COG3775	system Galactitol-specific IIC component
ANG_RS03940	COG3711	transcriptional antiterminator
ANG_RS03945	COG1447	Phosphotransferase system cellobiose-specific component IIA
ANG_RS03950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS03950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS03955	COG2723	6-phospho-beta-galactosidase activity
ANG_RS03960	COG1755	Isoprenylcysteine carboxyl methyltransferase
ANG_RS03965	COG2827	Endonuclease containing a URI domain
ANG_RS03970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ANG_RS03975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANG_RS03980	COG0204	Acyl-transferase
ANG_RS03995	COG1476	TRANSCRIPTIONal
ANG_RS04015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANG_RS04025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANG_RS04035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANG_RS04065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANG_RS04075	COG1573	uracil-dna glycosylase
ANG_RS04085	COG1174	glycine betaine transport
ANG_RS04090	COG1125	glycine betaine transport
ANG_RS04155	COG4974	Belongs to the 'phage' integrase family
ANG_RS04160	COG0254	rRNA binding
ANG_RS04165	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ANG_RS04170	COG0716	FMN binding
ANG_RS04190	COG1309	transcriptional regulator
ANG_RS04210	COG1959	2 iron, 2 sulfur cluster binding
ANG_RS04215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANG_RS04220	COG1349	DNA-binding transcription factor activity
ANG_RS04230	COG1447	Phosphotransferase system cellobiose-specific component IIA
ANG_RS04240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS04245	COG1882	Formate acetyltransferase
ANG_RS04275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ANG_RS04280	COG0406	alpha-ribazole phosphatase activity
ANG_RS04285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANG_RS04300	COG0772	Belongs to the SEDS family
ANG_RS04305	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ANG_RS04310	COG1595	DNA-templated transcription, initiation
ANG_RS04320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANG_RS04335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANG_RS04340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANG_RS04350	COG0813	purine-nucleoside phosphorylase activity
ANG_RS04360	COG1368	sulfuric ester hydrolase activity
ANG_RS04365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ANG_RS04370	COG0710	3-dehydroquinate dehydratase activity
ANG_RS04375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANG_RS04380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANG_RS04385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANG_RS04390	COG0730	response to heat
ANG_RS04400	COG0287	Prephenate dehydrogenase
ANG_RS04405	COG3679	Belongs to the UPF0342 family
ANG_RS04415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANG_RS04420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANG_RS04425	COG0077	Prephenate dehydratase
ANG_RS04435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANG_RS04490	COG0488	(ABC) transporter
ANG_RS04510	COG0556	nucleotide-excision repair
ANG_RS04520	COG1131	(ABC) transporter
ANG_RS04530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANG_RS04540	COG0647	UMP catabolic process
ANG_RS04560	COG1660	Displays ATPase and GTPase activities
ANG_RS04565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ANG_RS04570	COG1481	regulation of sporulation
ANG_RS04705	COG0551	DNA topoisomerase type I activity
ANG_RS04705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANG_RS04710	COG0542	response to heat
ANG_RS04830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ANG_RS04840	COG0540	Belongs to the ATCase OTCase family
ANG_RS04845	COG0505	Belongs to the CarA family
ANG_RS04850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANG_RS04855	COG2814	Major facilitator Superfamily
ANG_RS04860	COG0583	DNA-binding transcription factor activity
ANG_RS04885	COG0543	2 iron, 2 sulfur cluster binding
ANG_RS04890	COG0167	dihydroorotate dehydrogenase activity
ANG_RS04895	COG0284	orotidine-5'-phosphate decarboxylase activity
ANG_RS04905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANG_RS04920	COG4479	Belongs to the UPF0346 family
ANG_RS04925	COG1702	phosphate starvation-inducible protein PhoH
ANG_RS04945	COG0686	Belongs to the AlaDH PNT family
ANG_RS04955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANG_RS04975	COG1132	(ABC) transporter
ANG_RS04980	COG1132	(ABC) transporter
ANG_RS04985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANG_RS04990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ANG_RS04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANG_RS05020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANG_RS05025	COG0237	dephospho-CoA kinase activity
ANG_RS05035	COG2814	Major facilitator Superfamily
ANG_RS05045	COG0557	exoribonuclease II activity
ANG_RS05050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ANG_RS05060	COG2333	competence protein COMEC
ANG_RS05060	COG0658	competence protein
ANG_RS05075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANG_RS05080	COG1051	belongs to the nudix hydrolase family
ANG_RS05085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANG_RS05090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ANG_RS05095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANG_RS05105	COG4109	DRTGG domain
ANG_RS05110	COG0024	Methionine aminopeptidase
ANG_RS05120	COG1846	Transcriptional regulator
ANG_RS05140	COG4708	membrane
ANG_RS05150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANG_RS05155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANG_RS05160	COG1597	lipid kinase activity
ANG_RS05165	COG1523	belongs to the glycosyl hydrolase 13 family
ANG_RS05170	COG0228	four-way junction DNA binding
ANG_RS05175	COG1837	Belongs to the UPF0109 family
ANG_RS05180	COG1827	regulation of RNA biosynthetic process
ANG_RS05195	COG3142	Participates in the control of copper homeostasis
ANG_RS05200	COG2315	Protein conserved in bacteria
ANG_RS05205	COG1132	(ABC) transporter
ANG_RS05210	COG1132	(ABC) transporter
ANG_RS05220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANG_RS05235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANG_RS05240	COG1970	mechanosensitive ion channel activity
ANG_RS05245	COG0358	DNA primase activity
ANG_RS05250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANG_RS05255	COG2151	metal-sulfur cluster biosynthetic enzyme
ANG_RS05260	COG1114	Component of the transport system for branched-chain amino acids
ANG_RS05265	COG0785	Cytochrome C biogenesis protein
ANG_RS05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANG_RS05275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANG_RS05275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANG_RS05285	COG2972	Histidine kinase
ANG_RS05300	COG4555	ABC transporter
ANG_RS05305	COG1053	succinate dehydrogenase
ANG_RS05305	COG0431	NADPH-dependent FMN reductase
ANG_RS05305	COG3976	FMN-binding domain protein
ANG_RS05335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANG_RS05340	COG2233	PERMEase
ANG_RS05345	COG0534	Mate efflux family protein
ANG_RS05350	COG1942	4-Oxalocrotonate Tautomerase
ANG_RS05355	COG1435	thymidine kinase activity
ANG_RS05360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANG_RS05365	COG2890	protein-(glutamine-N5) methyltransferase activity
ANG_RS05375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANG_RS05385	COG0741	lytic transglycosylase activity
ANG_RS05460	COG4974	Belongs to the 'phage' integrase family
ANG_RS05470	COG2188	Transcriptional regulator
ANG_RS05480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANG_RS05485	COG0577	efflux transmembrane transporter activity
ANG_RS05485	COG1136	(ABC) transporter
ANG_RS05490	COG4974	Belongs to the 'phage' integrase family
ANG_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
ANG_RS05500	COG0095	Lipoate-protein ligase
ANG_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANG_RS05510	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANG_RS05515	COG0022	dehydrogenase e1 component
ANG_RS05520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANG_RS05540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ANG_RS05545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANG_RS05550	COG0758	DNA mediated transformation
ANG_RS05565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANG_RS05570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ANG_RS05575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANG_RS05580	COG1960	acyl-CoA dehydrogenase activity
ANG_RS05585	COG0583	DNA-binding transcription factor activity
ANG_RS05590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ANG_RS05600	COG1024	Enoyl-CoA hydratase
ANG_RS05610	COG0183	Belongs to the thiolase family
ANG_RS05615	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANG_RS05620	COG1960	acyl-CoA dehydrogenase activity
ANG_RS05625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANG_RS05630	COG3764	Sortase (surface protein transpeptidase)
ANG_RS05635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANG_RS05640	COG0039	L-malate dehydrogenase activity
ANG_RS05655	COG0539	negative regulation of cytoplasmic translation
ANG_RS05675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANG_RS05680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANG_RS05705	COG0187	DNA topoisomerase II activity
ANG_RS05710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ANG_RS05715	COG0737	Belongs to the 5'-nucleotidase family
ANG_RS05720	COG2976	Protein conserved in bacteria
ANG_RS05725	COG2131	deaminase
ANG_RS05730	COG1309	transcriptional regulator
ANG_RS05775	COG2814	Major facilitator Superfamily
ANG_RS05780	COG0017	Asparaginyl-tRNA synthetase
ANG_RS05790	COG0436	Aminotransferase
ANG_RS05800	COG1846	Transcriptional regulator
ANG_RS05805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANG_RS05810	COG3022	response to hydroperoxide
ANG_RS05820	COG1272	protein, Hemolysin III
ANG_RS05825	COG1079	Belongs to the binding-protein-dependent transport system permease family
ANG_RS05830	COG4603	Belongs to the binding-protein-dependent transport system permease family
ANG_RS05835	COG3845	ABC transporter
ANG_RS05840	COG1744	ABC transporter substrate-binding protein PnrA-like
ANG_RS05845	COG0295	cytidine deaminase activity
ANG_RS05850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANG_RS05860	COG2813	Specifically methylates the guanine in position
ANG_RS05865	COG1072	(Pantothenic acid kinase))
ANG_RS05870	COG0268	Binds directly to 16S ribosomal RNA
ANG_RS05880	COG4187	Peptidase family M20/M25/M40
ANG_RS05890	COG5002	protein histidine kinase activity
ANG_RS05895	COG0745	RESPONSE REGULATOR receiver
ANG_RS05945	COG1674	ftsk spoiiie
ANG_RS05980	COG1940	carbohydrate kinase activity
ANG_RS06015	COG2184	nucleotidyltransferase activity
ANG_RS06060	COG0083	homoserine kinase activity
ANG_RS06070	COG0726	polysaccharide deacetylase
ANG_RS06080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANG_RS06090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ANG_RS06095	COG1609	Transcriptional regulator
ANG_RS06100	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ANG_RS06100	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ANG_RS06115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANG_RS06120	COG1956	GAF domain-containing protein
ANG_RS06135	COG3443	Belongs to the bacterial solute-binding protein 9 family
ANG_RS06135	COG0803	Belongs to the bacterial solute-binding protein 9 family
ANG_RS06140	COG0336	Belongs to the RNA methyltransferase TrmD family
ANG_RS06145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANG_RS06160	COG0222	ribosome binding
ANG_RS06165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANG_RS06175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANG_RS06180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANG_RS06195	COG1247	-acetyltransferase
ANG_RS06200	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ANG_RS06210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANG_RS06215	COG4684	Psort location CytoplasmicMembrane, score
ANG_RS06220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANG_RS06230	COG1194	a g-specific adenine glycosylase
ANG_RS06270	COG1388	LysM domain
ANG_RS06395	COG0740	serine-type endopeptidase activity
ANG_RS06410	COG2801	Transposase and inactivated derivatives
ANG_RS06430	COG1484	DNA-dependent DNA replication
ANG_RS06440	COG4804	nuclease activity
ANG_RS06485	COG2205	protein histidine kinase activity
ANG_RS06490	COG0745	RESPONSE REGULATOR receiver
ANG_RS06535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANG_RS06545	COG0280	phosphate acetyltransferase
ANG_RS06550	COG0564	pseudouridine synthase activity
ANG_RS06560	COG2357	RelA SpoT domain protein
ANG_RS06570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ANG_RS06575	COG1104	cysteine desulfurase activity
ANG_RS06590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANG_RS06595	COG2003	Belongs to the UPF0758 family
ANG_RS06600	COG0704	Plays a role in the regulation of phosphate uptake
ANG_RS06605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANG_RS06610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANG_RS06615	COG0581	inorganic phosphate transmembrane transporter activity
ANG_RS06620	COG0573	inorganic phosphate transmembrane transporter activity
ANG_RS06630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ANG_RS06630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANG_RS06635	COG0483	inositol monophosphate 1-phosphatase activity
ANG_RS06640	COG4476	Belongs to the UPF0223 family
ANG_RS06645	COG1393	Belongs to the ArsC family
ANG_RS06650	COG0196	riboflavin kinase activity
ANG_RS06655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANG_RS06665	COG1132	(ABC) transporter
ANG_RS06670	COG2375	cellular response to nickel ion
ANG_RS06670	COG1132	(ABC) transporter
ANG_RS06675	COG2378	regulation of single-species biofilm formation
ANG_RS06685	COG0210	DNA helicase
ANG_RS06690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ANG_RS06700	COG1126	abc transporter atp-binding protein
ANG_RS06705	COG0765	amino acid transport
ANG_RS06715	COG0469	pyruvate kinase activity
ANG_RS06720	COG0205	6-phosphofructokinase activity
ANG_RS06730	COG1725	Transcriptional regulator
ANG_RS06735	COG1131	(ABC) transporter
ANG_RS06745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ANG_RS06745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANG_RS06760	COG0300	oxidoreductase activity
ANG_RS06780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ANG_RS06785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ANG_RS06790	COG0577	efflux transmembrane transporter activity
ANG_RS06795	COG1136	(ABC) transporter
ANG_RS06805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANG_RS06810	COG1268	BioY protein
ANG_RS06825	COG1011	Hydrolase
ANG_RS06845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANG_RS06845	COG0072	phenylalanine-tRNA ligase activity
ANG_RS06860	COG0488	(ABC) transporter
ANG_RS06865	COG0617	tRNA 3'-terminal CCA addition
ANG_RS06870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ANG_RS06875	COG1307	EDD domain protein, DegV family
ANG_RS06885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANG_RS06885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANG_RS06885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANG_RS06890	COG1105	Belongs to the carbohydrate kinase PfkB family
ANG_RS06895	COG1349	DNA-binding transcription factor activity
ANG_RS06905	COG0492	ferredoxin-NADP+ reductase activity
ANG_RS06910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANG_RS06935	COG0582	viral genome integration into host DNA
ANG_RS06950	COG1674	ftsk spoiiie
ANG_RS06985	COG1674	ftsk spoiiie
ANG_RS06995	COG1388	LysM domain
ANG_RS06995	COG1705	Flagellar rod assembly protein muramidase FlgJ
ANG_RS07000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ANG_RS07015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ANG_RS07020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ANG_RS07025	COG0038	chloride channel
ANG_RS07045	COG2824	Alkylphosphonate utilization operon protein PhnA
ANG_RS07055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANG_RS07060	COG0564	pseudouridine synthase activity
ANG_RS07070	COG0583	DNA-binding transcription factor activity
ANG_RS07080	COG1937	Protein conserved in bacteria
ANG_RS07095	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANG_RS07105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ANG_RS07115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANG_RS07120	COG0301	tRNA thio-modification
ANG_RS07125	COG1104	cysteine desulfurase activity
ANG_RS07130	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ANG_RS07135	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ANG_RS07140	COG0517	IMP dehydrogenase activity
ANG_RS07145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANG_RS07145	COG0574	Belongs to the PEP-utilizing enzyme family
ANG_RS07160	COG1177	transmembrane transport
ANG_RS07165	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANG_RS07170	COG3842	ATPase activity
ANG_RS07175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANG_RS07185	COG0481	GTPase activity
ANG_RS07190	COG0561	phosphatase activity
ANG_RS07195	COG2195	Cleaves the N-terminal amino acid of tripeptides
ANG_RS07205	COG0572	uridine kinase
ANG_RS07210	COG0673	inositol 2-dehydrogenase activity
ANG_RS07220	COG0726	polysaccharide deacetylase
ANG_RS07235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ANG_RS07245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANG_RS07270	COG0560	Phosphoserine phosphatase
ANG_RS07275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANG_RS07285	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ANG_RS07290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANG_RS07295	COG3442	glutamine amidotransferase
ANG_RS07305	COG0488	(ABC) transporter
ANG_RS07330	COG0826	peptidase U32
ANG_RS07355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANG_RS07360	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ANG_RS07375	COG3091	SprT-like family
ANG_RS07380	COG2183	response to ionizing radiation
ANG_RS07400	COG0701	Predicted permease
ANG_RS07405	COG3689	TIGRFAM TIGR03943 family protein
ANG_RS07410	COG0477	Major facilitator Superfamily
ANG_RS07415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANG_RS07420	COG0552	protein localization to endoplasmic reticulum
ANG_RS07425	COG0561	phosphatase activity
ANG_RS07430	COG0561	phosphatase activity
ANG_RS07435	COG1196	nuclear chromosome segregation
ANG_RS07440	COG0571	ribonuclease III activity
ANG_RS07450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ANG_RS07455	COG5002	protein histidine kinase activity
ANG_RS07460	COG0745	RESPONSE REGULATOR receiver
ANG_RS07470	COG0438	transferase activity, transferring glycosyl groups
ANG_RS07480	COG1609	Transcriptional regulator
ANG_RS07485	COG0006	proline dipeptidase activity
ANG_RS07490	COG1368	sulfuric ester hydrolase activity
ANG_RS07535	COG1091	dTDP-4-dehydrorhamnose reductase activity
ANG_RS07540	COG0463	Glycosyl transferase, family 2
ANG_RS07575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANG_RS07580	COG1088	dTDP-glucose 4,6-dehydratase activity
ANG_RS07590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ANG_RS07605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANG_RS07610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ANG_RS07615	COG2384	SAM-dependent methyltransferase
ANG_RS07625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ANG_RS07630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANG_RS07635	COG1346	cytolysis
ANG_RS07655	COG1132	(ABC) transporter
ANG_RS07675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANG_RS07695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANG_RS07700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANG_RS07705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANG_RS07710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANG_RS07715	COG0356	it plays a direct role in the translocation of protons across the membrane
ANG_RS07725	COG0058	SHG alpha-glucan phosphorylase activity
ANG_RS07730	COG0297	glycogen (starch) synthase activity
ANG_RS07735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANG_RS07740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANG_RS07745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANG_RS07750	COG1074	ATP-dependent DNA helicase activity
ANG_RS07755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ANG_RS07760	COG1668	transmembrane transport
ANG_RS07765	COG4152	abc transporter atp-binding protein
ANG_RS07770	COG4443	Transcriptional Coactivator p15 (PC4)
ANG_RS07780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANG_RS07795	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ANG_RS07800	COG3527	Alpha-acetolactate decarboxylase
ANG_RS07805	COG0028	Belongs to the TPP enzyme family
ANG_RS07815	COG0628	permease
ANG_RS07820	COG5002	protein histidine kinase activity
ANG_RS07820	COG3850	Histidine kinase
ANG_RS07825	COG0745	RESPONSE REGULATOR receiver
ANG_RS07830	COG2706	6-phosphogluconolactonase activity
ANG_RS07835	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ANG_RS07840	COG0187	DNA topoisomerase II activity
ANG_RS07855	COG0772	Belongs to the SEDS family
ANG_RS07865	COG1199	ATP-dependent helicase activity
ANG_RS07865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANG_RS07875	COG2177	Part of the ABC transporter FtsEX involved in
ANG_RS07880	COG2884	Cell division ATP-binding protein ftsE
ANG_RS07885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANG_RS07920	COG1078	dGTPase activity
ANG_RS07930	COG2348	transferase activity, transferring amino-acyl groups
ANG_RS07940	COG1132	(ABC) transporter
ANG_RS07945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANG_RS07955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANG_RS07960	COG4122	O-methyltransferase activity
ANG_RS07975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANG_RS07985	COG1447	Phosphotransferase system cellobiose-specific component IIA
ANG_RS07990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANG_RS07990	COG3711	transcriptional antiterminator
ANG_RS08000	COG4095	Psort location CytoplasmicMembrane, score
ANG_RS08010	COG2723	6-phospho-beta-galactosidase activity
ANG_RS08025	COG0363	glucosamine-6-phosphate deaminase activity
ANG_RS08030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ANG_RS08035	COG1438	arginine binding
ANG_RS08045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANG_RS08050	COG1288	antiporter activity
ANG_RS08055	COG0549	Belongs to the carbamate kinase family
ANG_RS08060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANG_RS08140	COG3290	protein histidine kinase activity
ANG_RS08150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANG_RS08155	COG2274	protein secretion by the type I secretion system
ANG_RS08165	COG2801	Transposase and inactivated derivatives
ANG_RS08175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ANG_RS08185	COG2996	Protein conserved in bacteria
ANG_RS08190	COG0233	cytoplasmic translational termination
ANG_RS08195	COG0528	UMP kinase activity
ANG_RS08200	COG0538	isocitrate dehydrogenase activity
ANG_RS08205	COG0372	Belongs to the citrate synthase family
ANG_RS08210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ANG_RS08215	COG0081	regulation of translation
ANG_RS08230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANG_RS08235	COG0697	spore germination
ANG_RS08235	COG1674	ftsk spoiiie
ANG_RS08240	COG1983	PspC domain protein
ANG_RS08255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANG_RS08260	COG0488	(ABC) transporter
ANG_RS08270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANG_RS08285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANG_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
ANG_RS08335	COG0531	amino acid
ANG_RS08340	COG0577	efflux transmembrane transporter activity
ANG_RS08345	COG1136	(ABC) transporter
ANG_RS08355	COG0642	Histidine kinase
ANG_RS08360	COG0745	RESPONSE REGULATOR receiver
ANG_RS08370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANG_RS08370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANG_RS08395	COG0640	Transcriptional regulator
ANG_RS08415	COG0708	Exodeoxyribonuclease III
ANG_RS08420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANG_RS08425	COG1393	Belongs to the ArsC family
ANG_RS08430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANG_RS08440	COG4467	Involved in initiation control of chromosome replication
ANG_RS08445	COG0470	DNA polymerase III
ANG_RS08455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ANG_RS08460	COG0517	IMP dehydrogenase activity
ANG_RS08475	COG4177	L-phenylalanine transmembrane transporter activity
ANG_RS08500	COG0740	serine-type endopeptidase activity
ANG_RS08505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANG_RS08510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANG_RS08515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ANG_RS08520	COG0626	cystathionine gamma-synthase activity
ANG_RS08525	COG2244	polysaccharide biosynthetic process
ANG_RS08530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANG_RS08555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANG_RS08565	COG0366	Alpha amylase catalytic
ANG_RS08570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANG_RS08570	COG1263	PTS System
ANG_RS08575	COG2188	Transcriptional regulator
ANG_RS08580	COG1253	flavin adenine dinucleotide binding
ANG_RS08590	COG0628	permease
ANG_RS08600	COG1846	Transcriptional regulator
ANG_RS08605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANG_RS08610	COG3599	regulation of cell shape
ANG_RS08625	COG1799	cell septum assembly
ANG_RS08630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANG_RS08635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANG_RS08645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ANG_RS08650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANG_RS08655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANG_RS08665	COG1217	gtp-binding protein TYPA
ANG_RS08670	COG1187	pseudouridine synthase activity
ANG_RS08700	COG2801	Transposase and inactivated derivatives
ANG_RS08715	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANG_RS08720	COG4470	Protein conserved in bacteria
ANG_RS08725	COG3480	Lon protease (S16) C-terminal proteolytic domain
ANG_RS08730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANG_RS08735	COG0742	ribosomal rna small subunit methyltransferase
ANG_RS08745	COG1040	competence protein
ANG_RS08750	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ANG_RS08755	COG1739	Uncharacterized protein family UPF0029
ANG_RS08790	COG0525	valine-tRNA ligase activity
ANG_RS08800	COG0519	Catalyzes the synthesis of GMP from XMP
ANG_RS08820	COG2070	2-Nitropropane dioxygenase
ANG_RS08830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANG_RS08835	COG2137	regulation of response to DNA damage stimulus
ANG_RS08840	COG3557	Belongs to the UPF0374 family
ANG_RS08850	COG1185	polyribonucleotide nucleotidyltransferase activity
ANG_RS08865	COG4585	Histidine kinase
ANG_RS08875	COG2815	serine threonine protein kinase
ANG_RS08875	COG0515	serine threonine protein kinase
ANG_RS08880	COG0631	protein serine/threonine phosphatase activity
ANG_RS08885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANG_RS08885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANG_RS08890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ANG_RS08895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANG_RS08900	COG1758	RNA polymerase activity
ANG_RS08905	COG0194	GDP metabolic process
ANG_RS08910	COG1418	mRNA catabolic process
ANG_RS08920	COG3634	alkyl hydroperoxide reductase activity
ANG_RS08925	COG0450	alkyl hydroperoxide reductase
ANG_RS08935	COG0116	Belongs to the methyltransferase superfamily
ANG_RS08940	COG3599	regulation of cell shape
ANG_RS08945	COG4474	Belongs to the UPF0398 family
ANG_RS08950	COG3331	DNA recombination
ANG_RS08955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANG_RS08960	COG3579	cysteine-type endopeptidase activity
ANG_RS08965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ANG_RS08970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ANG_RS08975	COG1113	amino acid transport
ANG_RS08980	COG0492	ferredoxin-NADP+ reductase activity
ANG_RS08990	COG1126	abc transporter atp-binding protein
ANG_RS09000	COG0513	Belongs to the DEAD box helicase family
ANG_RS09005	COG1686	Belongs to the peptidase S11 family
ANG_RS09015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANG_RS09020	COG0719	Fe-S assembly protein
ANG_RS09030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANG_RS09035	COG4862	establishment of competence for transformation
ANG_RS09040	COG1968	undecaprenyl-diphosphatase activity
ANG_RS09050	COG0765	amino acid transport
ANG_RS09055	COG1126	abc transporter atp-binding protein
ANG_RS09080	COG1131	(ABC) transporter
ANG_RS09120	COG2801	Transposase and inactivated derivatives
ANG_RS09135	COG1131	(ABC) transporter
ANG_RS09145	COG1461	Dihydroxyacetone kinase
ANG_RS09155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ANG_RS09180	COG0191	fructose-bisphosphate aldolase activity
ANG_RS09190	COG4166	transmembrane transport
ANG_RS09195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANG_RS09200	COG0768	penicillin binding
ANG_RS09220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANG_RS09235	COG0751	glycine-tRNA ligase activity
ANG_RS09240	COG0752	glycyl-tRNA synthetase alpha subunit
ANG_RS09255	COG1283	sodium-dependent phosphate transmembrane transporter activity
ANG_RS09260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANG_RS09275	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ANG_RS09280	COG0195	Participates in both transcription termination and antitermination
ANG_RS09285	COG0779	Required for maturation of 30S ribosomal subunits
ANG_RS09295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANG_RS09300	COG0510	thiamine kinase activity
ANG_RS09310	COG1131	(ABC) transporter
ANG_RS09315	COG0537	adenosine 5'-monophosphoramidase activity
ANG_RS09325	COG1316	TRANSCRIPTIONal
ANG_RS09335	COG0802	atpase or kinase
ANG_RS09340	COG2252	PERMEase
ANG_RS09350	COG0561	phosphatase activity
ANG_RS09365	COG3715	PTS system
ANG_RS09370	COG3716	PTS system mannose fructose sorbose family IID component
ANG_RS09385	COG0586	Pfam SNARE associated Golgi protein
ANG_RS09390	COG0825	malonyl-CoA metabolic process
ANG_RS09395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ANG_RS09400	COG0439	Biotin carboxylase
ANG_RS09405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANG_RS09415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANG_RS09425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANG_RS09430	COG2070	2-Nitropropane dioxygenase
ANG_RS09440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANG_RS09450	COG1024	Enoyl-CoA hydratase
ANG_RS09455	COG0527	aspartate kinase activity
ANG_RS09500	COG3590	peptidase
ANG_RS09525	COG1490	D-aminoacyl-tRNA deacylase activity
ANG_RS09535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANG_RS09540	COG2264	protein methyltransferase activity
ANG_RS09550	COG1051	belongs to the nudix hydrolase family
ANG_RS09560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANG_RS09590	COG1674	ftsk spoiiie
ANG_RS09620	COG1418	mRNA catabolic process
ANG_RS09625	COG1428	Deoxynucleoside kinase
ANG_RS09640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ANG_RS09665	COG1132	(ABC) transporter
ANG_RS09670	COG2375	cellular response to nickel ion
ANG_RS09670	COG1132	(ABC) transporter
ANG_RS09680	COG0601	transmembrane transport
ANG_RS09685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANG_RS09690	COG0444	Belongs to the ABC transporter superfamily
ANG_RS09700	COG0747	negative chemotaxis
ANG_RS09730	COG1401	restriction endodeoxyribonuclease activity
ANG_RS09765	COG0551	DNA topoisomerase type I activity
ANG_RS09765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANG_RS09850	COG0459	protein refolding
ANG_RS09855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANG_RS09865	COG3716	PTS system mannose fructose sorbose family IID component
ANG_RS09870	COG3715	PTS system
ANG_RS09890	COG2197	response regulator
ANG_RS09895	COG4585	Histidine kinase
ANG_RS09910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANG_RS09915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANG_RS09925	COG1363	Peptidase, m42
ANG_RS09935	COG0285	dihydrofolate synthase activity
ANG_RS09945	COG0442	prolyl-tRNA aminoacylation
ANG_RS09950	COG0750	zinc metalloprotease
ANG_RS09955	COG4589	Belongs to the CDS family
ANG_RS09960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ANG_RS09970	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
ANG_RS09975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ANG_RS09995	COG3623	hexulose-6-phosphate isomerase
ANG_RS10005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANG_RS10015	COG3037	sugar-specific permease SgaT UlaA
ANG_RS10030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANG_RS10060	COG4537	Required for transformation and DNA binding
ANG_RS10065	COG1459	type II secretion system
ANG_RS10070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANG_RS10080	COG0174	glutamine synthetase
ANG_RS10085	COG0789	Transcriptional regulator
ANG_RS10095	COG0126	phosphoglycerate kinase activity
ANG_RS10100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANG_RS10105	COG0085	RNA polymerase activity
ANG_RS10110	COG1136	(ABC) transporter
ANG_RS10110	COG0577	efflux transmembrane transporter activity
ANG_RS10130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ANG_RS10135	COG2226	methyltransferase
ANG_RS10145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ANG_RS10150	COG1473	amidohydrolase
ANG_RS10155	COG2171	N-acyltransferase activity
ANG_RS10160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANG_RS10165	COG0235	Class ii aldolase
ANG_RS10175	COG3775	system Galactitol-specific IIC component
ANG_RS10180	COG3414	Phosphotransferase system galactitol-specific IIB component
ANG_RS10185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANG_RS10200	COG0756	dUTP diphosphatase activity
ANG_RS10215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANG_RS10220	COG1882	Formate acetyltransferase
ANG_RS10235	COG3425	synthase
ANG_RS10245	COG1304	FMN binding
ANG_RS10265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ANG_RS10285	COG2801	Transposase and inactivated derivatives
ANG_RS10290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ANG_RS10295	COG2936	dipeptidyl-peptidase activity
ANG_RS10300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ANG_RS10310	COG1131	(ABC) transporter
ANG_RS10330	COG0584	glycerophosphoryl diester phosphodiesterase
ANG_RS10345	COG2081	HI0933 family
ANG_RS10360	COG1132	(ABC) transporter
ANG_RS10390	COG1396	sequence-specific DNA binding
ANG_RS10425	COG1674	ftsk spoiiie
ANG_RS10435	COG4115	mRNA cleavage
ANG_RS10475	COG0433	COG0433 Predicted ATPase
ANG_RS10490	COG3942	CHAP domain
ANG_RS10490	COG1705	Flagellar rod assembly protein muramidase FlgJ
ANG_RS10660	COG0582	viral genome integration into host DNA