locus-tag	class	description
GE024_RS00010	COG0592	DNA-directed DNA polymerase activity
GE024_RS00025	COG0012	GTP binding
GE024_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GE024_RS00040	COG2244	polysaccharide biosynthetic process
GE024_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GE024_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE024_RS00075	COG0531	amino acid
GE024_RS00100	COG4372	Transposase
GE024_RS00275	COG1792	Involved in formation and maintenance of cell shape
GE024_RS00285	COG3942	CHAP domain
GE024_RS00300	COG0416	fatty acid biosynthetic process
GE024_RS00305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE024_RS00310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GE024_RS00315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE024_RS00330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GE024_RS00335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GE024_RS00345	COG3942	CHAP domain
GE024_RS00350	COG0151	Belongs to the GarS family
GE024_RS00355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GE024_RS00365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GE024_RS00380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE024_RS00395	COG1454	alcohol dehydrogenase
GE024_RS00395	COG1012	belongs to the aldehyde dehydrogenase family
GE024_RS00400	COG1064	alcohol dehydrogenase
GE024_RS00420	COG0051	transcription antitermination factor activity, RNA binding
GE024_RS00520	COG0200	Binds to the 23S rRNA
GE024_RS00525	COG0201	protein transport
GE024_RS00545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GE024_RS00705	COG1252	NADH dehydrogenase
GE024_RS00710	COG1271	oxidase subunit
GE024_RS00715	COG1294	oxidase, subunit
GE024_RS00720	COG4988	ABC transporter
GE024_RS00725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GE024_RS00730	COG0142	geranyltranstransferase activity
GE024_RS00745	COG1121	(ABC) transporter
GE024_RS00750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE024_RS00760	COG0582	viral genome integration into host DNA
GE024_RS00820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE024_RS00820	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE024_RS00840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GE024_RS00845	COG1459	type II secretion system
GE024_RS00850	COG4537	Required for transformation and DNA binding
GE024_RS00875	COG2890	protein-(glutamine-N5) methyltransferase activity
GE024_RS00895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE024_RS00900	COG1363	Peptidase, m42
GE024_RS00915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE024_RS00920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE024_RS00930	COG1428	Deoxynucleoside kinase
GE024_RS00935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE024_RS00975	COG2031	fatty acid transporter
GE024_RS00985	COG0183	Belongs to the thiolase family
GE024_RS00990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GE024_RS01005	COG0251	oxidation-reduction process
GE024_RS01020	COG1269	ATP hydrolysis coupled proton transport
GE024_RS01025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GE024_RS01035	COG1527	subunit (C
GE024_RS01040	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
GE024_RS01070	COG1744	ABC transporter substrate-binding protein PnrA-like
GE024_RS01075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE024_RS01080	COG1349	DNA-binding transcription factor activity
GE024_RS01085	COG2390	Transcriptional regulator
GE024_RS01090	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE024_RS01095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS01100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS01105	COG1882	Formate acetyltransferase
GE024_RS01120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE024_RS01145	COG3655	Transcriptional regulator
GE024_RS01160	COG2205	protein histidine kinase activity
GE024_RS01165	COG0745	RESPONSE REGULATOR receiver
GE024_RS01175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GE024_RS01180	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GE024_RS01185	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GE024_RS01220	COG2207	Transcriptional regulator
GE024_RS01230	COG1175	transmembrane transport
GE024_RS01235	COG0395	ABC-type sugar transport system, permease component
GE024_RS01250	COG2017	converts alpha-aldose to the beta-anomer
GE024_RS01255	COG1609	Transcriptional regulator
GE024_RS01260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GE024_RS01265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GE024_RS01270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE024_RS01300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GE024_RS01305	COG0512	Glutamine amidotransferase of anthranilate synthase
GE024_RS01310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GE024_RS01315	COG0154	amidase activity
GE024_RS01335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GE024_RS01340	COG1609	Transcriptional regulator
GE024_RS01345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE024_RS01345	COG2190	(PTS) system
GE024_RS01345	COG1263	PTS System
GE024_RS01355	COG1363	Peptidase, m42
GE024_RS01395	COG3842	ATPase activity
GE024_RS01405	COG1523	belongs to the glycosyl hydrolase 13 family
GE024_RS01420	COG1862	Preprotein translocase
GE024_RS01430	COG4589	Belongs to the CDS family
GE024_RS01455	COG1846	Transcriptional regulator
GE024_RS01495	COG3037	sugar-specific permease SgaT UlaA
GE024_RS01500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GE024_RS01515	COG1045	serine acetyltransferase
GE024_RS01530	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GE024_RS01545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE024_RS01565	COG1476	TRANSCRIPTIONal
GE024_RS01570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GE024_RS01660	COG4372	Transposase
GE024_RS01705	COG0351	phosphomethylpyrimidine kinase
GE024_RS01710	COG4720	Psort location CytoplasmicMembrane, score
GE024_RS01720	COG0668	transmembrane transport
GE024_RS01725	COG0544	peptidyl-prolyl cis-trans isomerase activity
GE024_RS01730	COG3343	RNA polymerase activity
GE024_RS01745	COG3279	Response regulator of the LytR AlgR family
GE024_RS01755	COG1346	cytolysis
GE024_RS01790	COG1461	Dihydroxyacetone kinase
GE024_RS01810	COG0765	amino acid transport
GE024_RS01825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE024_RS01835	COG0719	Fe-S assembly protein
GE024_RS01840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE024_RS01860	COG1686	Belongs to the peptidase S11 family
GE024_RS01865	COG1686	Belongs to the peptidase S11 family
GE024_RS01870	COG4166	transmembrane transport
GE024_RS01875	COG0601	transmembrane transport
GE024_RS01880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE024_RS01885	COG0444	Belongs to the ABC transporter superfamily
GE024_RS01945	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GE024_RS01950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE024_RS01955	COG1534	Rna-binding protein
GE024_RS01965	COG1713	HD superfamily hydrolase involved in NAD metabolism
GE024_RS01980	COG0799	negative regulation of ribosome biogenesis
GE024_RS01985	COG2226	methyltransferase
GE024_RS01990	COG1323	Belongs to the UPF0348 family
GE024_RS01995	COG0789	Transcriptional regulator
GE024_RS02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE024_RS02010	COG1464	Belongs to the NlpA lipoprotein family
GE024_RS02030	COG1114	Component of the transport system for branched-chain amino acids
GE024_RS02040	COG0569	domain protein
GE024_RS02045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE024_RS02055	COG1704	LemA family
GE024_RS02060	COG0501	Belongs to the peptidase M48B family
GE024_RS02070	COG0745	RESPONSE REGULATOR receiver
GE024_RS02075	COG5002	protein histidine kinase activity
GE024_RS02080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE024_RS02090	COG1484	DNA-dependent DNA replication
GE024_RS02100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE024_RS02120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GE024_RS02135	COG1254	Belongs to the acylphosphatase family
GE024_RS02145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE024_RS02200	COG1187	pseudouridine synthase activity
GE024_RS02230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GE024_RS02235	COG0671	phosphoesterase, PA-phosphatase related
GE024_RS02240	COG1242	4 iron, 4 sulfur cluster binding
GE024_RS02245	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GE024_RS02250	COG1253	flavin adenine dinucleotide binding
GE024_RS02255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE024_RS02270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE024_RS02275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE024_RS02280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE024_RS02285	COG1120	ATPase activity
GE024_RS02295	COG2244	polysaccharide biosynthetic process
GE024_RS02330	COG0470	DNA polymerase III
GE024_RS02335	COG1774	PSP1 C-terminal conserved region
GE024_RS02370	COG1393	Belongs to the ArsC family
GE024_RS02385	COG1609	Transcriptional regulator
GE024_RS02390	COG0561	phosphatase activity
GE024_RS02395	COG0708	Exodeoxyribonuclease III
GE024_RS02410	COG1304	FMN binding
GE024_RS02450	COG1114	Component of the transport system for branched-chain amino acids
GE024_RS02470	COG1028	Short-chain dehydrogenase reductase Sdr
GE024_RS02485	COG0673	inositol 2-dehydrogenase activity
GE024_RS02510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GE024_RS02595	COG1702	phosphate starvation-inducible protein PhoH
GE024_RS02600	COG1573	uracil-dna glycosylase
GE024_RS02610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GE024_RS02660	COG1131	(ABC) transporter
GE024_RS02670	COG0433	COG0433 Predicted ATPase
GE024_RS02675	COG2814	Major facilitator Superfamily
GE024_RS02690	COG0557	exoribonuclease II activity
GE024_RS02695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GE024_RS02705	COG0463	Glycosyl transferase, family 2
GE024_RS02710	COG0346	lactoylglutathione lyase activity
GE024_RS02715	COG0778	Nitroreductase
GE024_RS02720	COG0006	proline dipeptidase activity
GE024_RS02725	COG1609	Transcriptional regulator
GE024_RS02740	COG0438	transferase activity, transferring glycosyl groups
GE024_RS02750	COG4555	ABC transporter
GE024_RS02770	COG2376	Dihydroxyacetone kinase
GE024_RS02780	COG2376	Dihydroxyacetone kinase
GE024_RS02785	COG1461	Dihydroxyacetone kinase
GE024_RS02790	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GE024_RS02795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE024_RS02805	COG0745	RESPONSE REGULATOR receiver
GE024_RS02810	COG5002	protein histidine kinase activity
GE024_RS02815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE024_RS02825	COG1196	nuclear chromosome segregation
GE024_RS02835	COG0561	phosphatase activity
GE024_RS02840	COG0561	phosphatase activity
GE024_RS02845	COG0552	protein localization to endoplasmic reticulum
GE024_RS02850	COG0477	Major facilitator Superfamily
GE024_RS02855	COG3711	transcriptional antiterminator
GE024_RS02860	COG1263	PTS System
GE024_RS02860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE024_RS02860	COG2190	(PTS) system
GE024_RS02870	COG3689	TIGRFAM TIGR03943 family protein
GE024_RS02875	COG0701	Predicted permease
GE024_RS02895	COG2183	response to ionizing radiation
GE024_RS02945	COG0826	peptidase U32
GE024_RS02950	COG4443	Transcriptional Coactivator p15 (PC4)
GE024_RS02960	COG2801	Transposase and inactivated derivatives
GE024_RS02985	COG2801	Transposase and inactivated derivatives
GE024_RS02990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GE024_RS03015	COG0386	Belongs to the glutathione peroxidase family
GE024_RS03020	COG1164	Oligoendopeptidase f
GE024_RS03030	COG0772	Belongs to the SEDS family
GE024_RS03075	COG2348	transferase activity, transferring amino-acyl groups
GE024_RS03085	COG1078	dGTPase activity
GE024_RS03100	COG1609	Transcriptional regulator
GE024_RS03110	COG3716	PTS system mannose fructose sorbose family IID component
GE024_RS03115	COG3715	PTS system
GE024_RS03120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE024_RS03135	COG1028	Short-chain dehydrogenase reductase Sdr
GE024_RS03150	COG0800	Aldolase
GE024_RS03175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GE024_RS03180	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GE024_RS03185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GE024_RS03195	COG2884	Cell division ATP-binding protein ftsE
GE024_RS03200	COG2177	Part of the ABC transporter FtsEX involved in
GE024_RS03210	COG1199	ATP-dependent helicase activity
GE024_RS03210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GE024_RS03215	COG0436	Aminotransferase
GE024_RS03220	COG0017	Asparaginyl-tRNA synthetase
GE024_RS03260	COG2188	Transcriptional regulator
GE024_RS03265	COG2222	sugar isomerase
GE024_RS03290	COG3715	PTS system
GE024_RS03295	COG3716	PTS system mannose fructose sorbose family IID component
GE024_RS03310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GE024_RS03315	COG2153	protein acetylation
GE024_RS03330	COG0716	FMN binding
GE024_RS03340	COG0038	chloride channel
GE024_RS03355	COG0772	Belongs to the SEDS family
GE024_RS03425	COG1131	(ABC) transporter
GE024_RS03445	COG4708	membrane
GE024_RS03455	COG1597	lipid kinase activity
GE024_RS03460	COG1523	belongs to the glycosyl hydrolase 13 family
GE024_RS03465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GE024_RS03470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE024_RS03475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE024_RS03555	COG2801	Transposase and inactivated derivatives
GE024_RS03595	COG0436	Aminotransferase
GE024_RS03600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE024_RS03610	COG1970	mechanosensitive ion channel activity
GE024_RS03615	COG0358	DNA primase activity
GE024_RS03620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GE024_RS03625	COG2151	metal-sulfur cluster biosynthetic enzyme
GE024_RS03680	COG1216	Glycosyl transferase, family 2
GE024_RS03695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE024_RS03710	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE024_RS03755	COG1368	sulfuric ester hydrolase activity
GE024_RS03760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GE024_RS03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE024_RS03785	COG0285	dihydrofolate synthase activity
GE024_RS03795	COG1104	cysteine desulfurase activity
GE024_RS03820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GE024_RS03825	COG0583	DNA-binding transcription factor activity
GE024_RS03835	COG0564	pseudouridine synthase activity
GE024_RS03875	COG1136	(ABC) transporter
GE024_RS03880	COG0577	efflux transmembrane transporter activity
GE024_RS03890	COG0584	glycerophosphoryl diester phosphodiesterase
GE024_RS03900	COG1837	Belongs to the UPF0109 family
GE024_RS03930	COG1349	DNA-binding transcription factor activity
GE024_RS03935	COG1105	Belongs to the carbohydrate kinase PfkB family
GE024_RS03940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE024_RS03940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE024_RS03940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE024_RS03945	COG1388	LysM domain
GE024_RS03945	COG1705	Flagellar rod assembly protein muramidase FlgJ
GE024_RS03950	COG1705	Flagellar rod assembly protein muramidase FlgJ
GE024_RS03950	COG1388	LysM domain
GE024_RS03975	COG0488	(ABC) transporter
GE024_RS03980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE024_RS03985	COG0242	peptide deformylase activity
GE024_RS03990	COG0737	Belongs to the 5'-nucleotidase family
GE024_RS03995	COG1132	(ABC) transporter
GE024_RS04000	COG1132	(ABC) transporter
GE024_RS04035	COG3425	synthase
GE024_RS04045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE024_RS04120	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE024_RS04300	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE024_RS04310	COG1131	(ABC) transporter
GE024_RS04315	COG0842	Transport permease protein
GE024_RS04330	COG2217	Heavy metal translocating P-type atpase
GE024_RS04335	COG0640	Transcriptional regulator
GE024_RS04355	COG1674	ftsk spoiiie
GE024_RS04365	COG2946	Replication initiation factor
GE024_RS04395	COG0741	lytic transglycosylase activity
GE024_RS04395	COG0791	NLP P60 protein
GE024_RS04465	COG1388	LysM domain
GE024_RS04465	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE024_RS04505	COG2217	Heavy metal translocating P-type atpase
GE024_RS04510	COG2217	Heavy metal translocating P-type atpase
GE024_RS04555	COG3843	relaxase mobilization nuclease domain protein
GE024_RS04560	COG1396	sequence-specific DNA binding
GE024_RS04570	COG4974	Belongs to the 'phage' integrase family
GE024_RS04585	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE024_RS04670	COG0463	Glycosyl transferase, family 2
GE024_RS04685	COG2274	protein secretion by the type I secretion system
GE024_RS04740	COG1396	sequence-specific DNA binding
GE024_RS04745	COG0602	queuosine metabolic process
GE024_RS04760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GE024_RS04805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GE024_RS04830	COG3843	relaxase mobilization nuclease domain protein
GE024_RS04835	COG1349	DNA-binding transcription factor activity
GE024_RS04845	COG0698	ribose 5-phosphate isomerase
GE024_RS04850	COG1105	Belongs to the carbohydrate kinase PfkB family
GE024_RS04855	COG3684	Belongs to the aldolase LacD family
GE024_RS04860	COG3711	transcriptional antiterminator
GE024_RS04870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS04870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS04890	COG1396	sequence-specific DNA binding
GE024_RS04900	COG4974	Belongs to the 'phage' integrase family
GE024_RS04985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE024_RS04990	COG0765	amino acid transport
GE024_RS05010	COG0187	DNA topoisomerase II activity
GE024_RS05025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE024_RS05045	COG0539	negative regulation of cytoplasmic translation
GE024_RS05055	COG0726	polysaccharide deacetylase
GE024_RS05080	COG0285	dihydrofolate synthase activity
GE024_RS05085	COG0302	gtp cyclohydrolase
GE024_RS05100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GE024_RS05115	COG1176	ABC-type spermidine putrescine transport system, permease component I
GE024_RS05120	COG1177	transmembrane transport
GE024_RS05150	COG0628	permease
GE024_RS05160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GE024_RS05180	COG1104	cysteine desulfurase activity
GE024_RS05195	COG2357	RelA SpoT domain protein
GE024_RS05205	COG0564	pseudouridine synthase activity
GE024_RS05210	COG0280	phosphate acetyltransferase
GE024_RS05215	COG4221	oxidoreductase activity
GE024_RS05230	COG1174	glycine betaine transport
GE024_RS05245	COG2233	PERMEase
GE024_RS05270	COG2890	protein-(glutamine-N5) methyltransferase activity
GE024_RS05325	COG3764	Sortase (surface protein transpeptidase)
GE024_RS05330	COG0346	lactoylglutathione lyase activity
GE024_RS05335	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE024_RS05350	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE024_RS05415	COG2188	Transcriptional regulator
GE024_RS05425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GE024_RS05455	COG4939	FMN-binding domain protein
GE024_RS05460	COG0142	geranyltranstransferase activity
GE024_RS05465	COG1252	NADH dehydrogenase
GE024_RS05475	COG5002	protein histidine kinase activity
GE024_RS05480	COG0745	RESPONSE REGULATOR receiver
GE024_RS05485	COG0577	efflux transmembrane transporter activity
GE024_RS05490	COG1136	(ABC) transporter
GE024_RS05520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE024_RS05525	COG0758	DNA mediated transformation
GE024_RS05545	COG1272	protein, Hemolysin III
GE024_RS05565	COG0488	(ABC) transporter
GE024_RS05580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE024_RS05585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE024_RS05585	COG1328	CTP reductase activity
GE024_RS05590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE024_RS05620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE024_RS05630	COG0095	Lipoate-protein ligase
GE024_RS05640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE024_RS05645	COG4684	Psort location CytoplasmicMembrane, score
GE024_RS05650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE024_RS05660	COG1079	Belongs to the binding-protein-dependent transport system permease family
GE024_RS05665	COG4603	Belongs to the binding-protein-dependent transport system permease family
GE024_RS05670	COG3845	ABC transporter
GE024_RS05675	COG1744	ABC transporter substrate-binding protein PnrA-like
GE024_RS05690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GE024_RS05695	COG2813	Specifically methylates the guanine in position
GE024_RS05710	COG5002	protein histidine kinase activity
GE024_RS05715	COG0745	RESPONSE REGULATOR receiver
GE024_RS05725	COG0704	Plays a role in the regulation of phosphate uptake
GE024_RS05740	COG0581	inorganic phosphate transmembrane transporter activity
GE024_RS05745	COG0573	inorganic phosphate transmembrane transporter activity
GE024_RS05755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE024_RS05755	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GE024_RS05760	COG0483	inositol monophosphate 1-phosphatase activity
GE024_RS05775	COG0196	riboflavin kinase activity
GE024_RS05805	COG4591	ABC-type transport system involved in lipoprotein release permease component
GE024_RS05805	COG1136	(ABC) transporter
GE024_RS05845	COG2261	transglycosylase associated protein
GE024_RS05855	COG1115	amino acid carrier protein
GE024_RS05860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE024_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE024_RS05875	COG1126	abc transporter atp-binding protein
GE024_RS05880	COG0765	amino acid transport
GE024_RS05885	COG2824	Alkylphosphonate utilization operon protein PhnA
GE024_RS05900	COG0469	pyruvate kinase activity
GE024_RS05915	COG1725	Transcriptional regulator
GE024_RS05920	COG1131	(ABC) transporter
GE024_RS05930	COG0398	Pfam SNARE associated Golgi protein
GE024_RS05965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE024_RS05975	COG0028	Belongs to the TPP enzyme family
GE024_RS05990	COG1012	belongs to the aldehyde dehydrogenase family
GE024_RS05995	COG1011	Hydrolase
GE024_RS06010	COG1840	ABC-type Fe3 transport system, periplasmic component
GE024_RS06015	COG2207	Transcriptional regulator
GE024_RS06015	COG4753	response regulator
GE024_RS06020	COG2972	Histidine kinase
GE024_RS06025	COG3716	PTS system mannose fructose sorbose family IID component
GE024_RS06030	COG3715	PTS system
GE024_RS06070	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GE024_RS06075	COG1518	maintenance of DNA repeat elements
GE024_RS06090	COG0647	UMP catabolic process
GE024_RS06100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE024_RS06120	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GE024_RS06125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE024_RS06130	COG3442	glutamine amidotransferase
GE024_RS06135	COG0095	Lipoate-protein ligase
GE024_RS06165	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE024_RS06170	COG0022	dehydrogenase e1 component
GE024_RS06170	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE024_RS06175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE024_RS06180	COG0488	(ABC) transporter
GE024_RS06200	COG1122	ATPase activity
GE024_RS06220	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GE024_RS06225	COG0457	Tetratricopeptide repeat
GE024_RS06230	COG0628	permease
GE024_RS06235	COG1051	belongs to the nudix hydrolase family
GE024_RS06240	COG2706	6-phosphogluconolactonase activity
GE024_RS06250	COG1088	dTDP-glucose 4,6-dehydratase activity
GE024_RS06260	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE024_RS06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE024_RS06280	COG2384	SAM-dependent methyltransferase
GE024_RS06285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GE024_RS06300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GE024_RS06300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GE024_RS06305	COG0300	oxidoreductase activity
GE024_RS06315	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GE024_RS06320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE024_RS06350	COG1054	Belongs to the UPF0176 family
GE024_RS06365	COG0058	SHG alpha-glucan phosphorylase activity
GE024_RS06370	COG1640	4-alpha-glucanotransferase
GE024_RS06375	COG1609	Transcriptional regulator
GE024_RS06380	COG2182	Extracellular solute-binding protein
GE024_RS06385	COG1175	transmembrane transport
GE024_RS06390	COG3833	ABC-type maltose transport systems, permease component
GE024_RS06405	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE024_RS06415	COG1696	Membrane protein involved in D-alanine export
GE024_RS06430	COG0556	nucleotide-excision repair
GE024_RS06435	COG0765	amino acid transport
GE024_RS06440	COG1126	abc transporter atp-binding protein
GE024_RS06445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS06455	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE024_RS06465	COG3711	transcriptional antiterminator
GE024_RS06465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE024_RS06475	COG2723	6-phospho-beta-galactosidase activity
GE024_RS06500	COG2309	aminopeptidase activity
GE024_RS06510	COG1187	pseudouridine synthase activity
GE024_RS06520	COG2814	Major facilitator Superfamily
GE024_RS06540	COG1464	Belongs to the NlpA lipoprotein family
GE024_RS06565	COG1940	carbohydrate kinase activity
GE024_RS06570	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE024_RS06585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE024_RS06650	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE024_RS06655	COG1475	DNA binding
GE024_RS06720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS06720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS06750	COG1191	sigma factor activity
GE024_RS06810	COG0798	PFAM Bile acid sodium symporter
GE024_RS06820	COG0701	Predicted permease
GE024_RS06825	COG0640	Transcriptional regulator
GE024_RS06850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS06850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS06975	COG0740	serine-type endopeptidase activity
GE024_RS06990	COG3177	Filamentation induced by cAMP protein fic
GE024_RS06995	COG4626	Terminase
GE024_RS06995	COG1802	Transcriptional regulator
GE024_RS07020	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE024_RS07025	COG1475	DNA binding
GE024_RS07085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GE024_RS07110	COG1316	TRANSCRIPTIONal
GE024_RS07135	COG4109	DRTGG domain
GE024_RS07145	COG2186	Transcriptional regulator
GE024_RS07170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GE024_RS07170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GE024_RS07180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GE024_RS07200	COG0513	Belongs to the DEAD box helicase family
GE024_RS07205	COG0726	polysaccharide deacetylase
GE024_RS07210	COG1012	belongs to the aldehyde dehydrogenase family
GE024_RS07225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GE024_RS07230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE024_RS07235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE024_RS07255	COG1476	TRANSCRIPTIONal
GE024_RS07270	COG4122	O-methyltransferase activity
GE024_RS07275	COG2223	nitrite transmembrane transporter activity
GE024_RS07285	COG0546	phosphoglycolate phosphatase activity
GE024_RS07315	COG1187	pseudouridine synthase activity
GE024_RS07355	COG0658	competence protein
GE024_RS07355	COG2333	competence protein COMEC
GE024_RS07360	COG1596	polysaccharide export
GE024_RS07360	COG1555	photosystem II stabilization
GE024_RS07365	COG0204	Acyl-transferase
GE024_RS07370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GE024_RS07385	COG0513	Belongs to the DEAD box helicase family
GE024_RS07395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GE024_RS07415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE024_RS07430	COG0768	penicillin binding
GE024_RS07435	COG2116	formate transmembrane transporter activity
GE024_RS07445	COG1827	regulation of RNA biosynthetic process
GE024_RS07460	COG2217	Heavy metal translocating P-type atpase
GE024_RS07480	COG2755	lipolytic protein G-D-S-L family
GE024_RS07495	COG0497	DNA recombination
GE024_RS07500	COG1438	arginine binding
GE024_RS07505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GE024_RS07525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GE024_RS07535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE024_RS07550	COG1378	Sugar-specific transcriptional regulator TrmB
GE024_RS07575	COG0765	amino acid transport
GE024_RS07580	COG4703	Protein of unknown function (DUF1797)
GE024_RS07585	COG0542	response to heat
GE024_RS07610	COG3599	regulation of cell shape
GE024_RS07630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GE024_RS07670	COG1217	gtp-binding protein TYPA
GE024_RS07680	COG1940	carbohydrate kinase activity
GE024_RS07690	COG0783	Belongs to the Dps family
GE024_RS07695	COG1132	(ABC) transporter
GE024_RS07700	COG1132	(ABC) transporter
GE024_RS07710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GE024_RS07715	COG4470	Protein conserved in bacteria
GE024_RS07720	COG1879	ABC-type sugar transport system periplasmic component
GE024_RS07725	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE024_RS07735	COG1869	D-ribose catabolic process
GE024_RS07740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE024_RS07745	COG1609	Transcriptional regulator
GE024_RS07755	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE024_RS07765	COG0742	ribosomal rna small subunit methyltransferase
GE024_RS07775	COG0549	Belongs to the carbamate kinase family
GE024_RS07780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE024_RS07785	COG1288	antiporter activity
GE024_RS07795	COG0454	-acetyltransferase
GE024_RS07800	COG2235	arginine
GE024_RS07825	COG2972	Histidine kinase
GE024_RS07840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE024_RS07845	COG0785	Cytochrome C biogenesis protein
GE024_RS07850	COG0673	inositol 2-dehydrogenase activity
GE024_RS07875	COG0346	lactoylglutathione lyase activity
GE024_RS07895	COG0534	Mate efflux family protein
GE024_RS07930	COG1215	transferase activity, transferring glycosyl groups
GE024_RS07935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GE024_RS07935	COG1605	Chorismate mutase
GE024_RS07950	COG3250	beta-galactosidase activity
GE024_RS07955	COG2207	Transcriptional regulator
GE024_RS07955	COG4753	response regulator
GE024_RS07960	COG2972	Histidine kinase
GE024_RS07970	COG1653	transport
GE024_RS07975	COG0395	ABC-type sugar transport system, permease component
GE024_RS07980	COG1175	transmembrane transport
GE024_RS08000	COG2723	6-phospho-beta-galactosidase activity
GE024_RS08005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GE024_RS08020	COG0383	alpha-mannosidase activity
GE024_RS08125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GE024_RS08130	COG1739	Uncharacterized protein family UPF0029
GE024_RS08145	COG1098	S1 RNA binding domain
GE024_RS08155	COG2197	response regulator
GE024_RS08160	COG4585	Histidine kinase
GE024_RS08170	COG2815	serine threonine protein kinase
GE024_RS08170	COG0515	serine threonine protein kinase
GE024_RS08180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE024_RS08180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE024_RS08190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GE024_RS08215	COG0183	Belongs to the thiolase family
GE024_RS08235	COG0116	Belongs to the methyltransferase superfamily
GE024_RS08260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE024_RS08265	COG3579	cysteine-type endopeptidase activity
GE024_RS08275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GE024_RS08280	COG1113	amino acid transport
GE024_RS08295	COG1126	abc transporter atp-binding protein
GE024_RS08300	COG0765	amino acid transport
GE024_RS08310	COG0513	Belongs to the DEAD box helicase family
GE024_RS08320	COG0768	penicillin binding
GE024_RS08360	COG1131	(ABC) transporter
GE024_RS08385	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE024_RS08390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE024_RS08425	COG1755	Isoprenylcysteine carboxyl methyltransferase
GE024_RS08430	COG0656	L-ascorbic acid biosynthetic process
GE024_RS08440	COG1283	sodium-dependent phosphate transmembrane transporter activity
GE024_RS08460	COG0561	phosphatase activity
GE024_RS08465	COG2860	membrane
GE024_RS08480	COG1105	Belongs to the carbohydrate kinase PfkB family
GE024_RS08520	COG2217	Heavy metal translocating P-type atpase
GE024_RS08555	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GE024_RS08560	COG0195	Participates in both transcription termination and antitermination
GE024_RS08585	COG4473	ABC transporter
GE024_RS08590	COG1131	(ABC) transporter
GE024_RS08595	COG0537	adenosine 5'-monophosphoramidase activity
GE024_RS08605	COG1316	TRANSCRIPTIONal
GE024_RS08610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE024_RS08615	COG0802	atpase or kinase
GE024_RS08620	COG2252	PERMEase
GE024_RS08625	COG0561	phosphatase activity
GE024_RS08635	COG3715	PTS system
GE024_RS08640	COG3716	PTS system mannose fructose sorbose family IID component
GE024_RS08675	COG0439	Biotin carboxylase
GE024_RS08690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE024_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
GE024_RS08700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE024_RS08725	COG1024	Enoyl-CoA hydratase
GE024_RS08730	COG0484	heat shock protein binding
GE024_RS08745	COG1420	regulation of RNA biosynthetic process
GE024_RS08760	COG0588	phosphoglycerate mutase activity
GE024_RS08765	COG2261	transglycosylase associated protein
GE024_RS08770	COG0697	spore germination
GE024_RS08790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GE024_RS08790	COG0574	Belongs to the PEP-utilizing enzyme family
GE024_RS08795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GE024_RS08800	COG0517	IMP dehydrogenase activity
GE024_RS08805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE024_RS08810	COG1335	isochorismatase
GE024_RS08820	COG0436	Aminotransferase
GE024_RS08830	COG0561	phosphatase activity
GE024_RS08835	COG0252	asparaginase activity
GE024_RS08840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GE024_RS08845	COG1129	ABC transporter
GE024_RS08860	COG1132	(ABC) transporter
GE024_RS08865	COG4988	ABC transporter
GE024_RS08870	COG1120	ATPase activity
GE024_RS08895	COG1388	LysM domain
GE024_RS08895	COG3942	CHAP domain
GE024_RS08915	COG1482	cell wall glycoprotein biosynthetic process
GE024_RS08920	COG1940	carbohydrate kinase activity
GE024_RS08930	COG2190	(PTS) system
GE024_RS08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE024_RS08930	COG1263	PTS System
GE024_RS08935	COG1621	beta-fructofuranosidase activity
GE024_RS08940	COG1609	Transcriptional regulator
GE024_RS08960	COG2131	deaminase
GE024_RS08965	COG0006	proline dipeptidase activity
GE024_RS09015	COG1194	a g-specific adenine glycosylase
GE024_RS09020	COG3118	belongs to the thioredoxin family
GE024_RS09025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE024_RS09055	COG0681	Belongs to the peptidase S26 family
GE024_RS09060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GE024_RS09075	COG1882	Formate acetyltransferase
GE024_RS09085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE024_RS09100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE024_RS09145	COG0789	Transcriptional regulator
GE024_RS09160	COG2081	HI0933 family
GE024_RS09180	COG1214	PFAM Peptidase M22, glycoprotease
GE024_RS09185	COG5503	Protein of unknown function (DUF1447)
GE024_RS09195	COG4608	Belongs to the ABC transporter superfamily
GE024_RS09200	COG0444	Belongs to the ABC transporter superfamily
GE024_RS09205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE024_RS09210	COG0601	transmembrane transport
GE024_RS09220	COG4166	transmembrane transport
GE024_RS09225	COG0174	glutamine synthetase
GE024_RS09230	COG0789	Transcriptional regulator
GE024_RS09245	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GE024_RS09275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE024_RS09290	COG1564	THIamine pyrophosphokinase
GE024_RS09305	COG2814	Major facilitator Superfamily
GE024_RS09315	COG1288	antiporter activity
GE024_RS09320	COG0549	Belongs to the carbamate kinase family
GE024_RS09325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GE024_RS09335	COG0784	Response regulator, receiver
GE024_RS09350	COG0084	hydrolase, TatD family'
GE024_RS09360	COG2814	Major facilitator Superfamily
GE024_RS09365	COG1335	isochorismatase
GE024_RS09375	COG2190	(PTS) system
GE024_RS09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE024_RS09375	COG1263	PTS System
GE024_RS09435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GE024_RS09455	COG0673	inositol 2-dehydrogenase activity
GE024_RS09460	COG4409	exo-alpha-(2->6)-sialidase activity
GE024_RS09470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE024_RS09475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GE024_RS09480	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GE024_RS09540	COG0542	response to heat
GE024_RS09660	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE024_RS09750	COG0756	dUTP diphosphatase activity
GE024_RS09760	COG1132	(ABC) transporter
GE024_RS09765	COG1132	(ABC) transporter
GE024_RS09775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GE024_RS09780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE024_RS09785	COG0457	Tetratricopeptide repeat
GE024_RS09785	COG0705	Rhomboid family
GE024_RS09790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GE024_RS09840	COG1234	tRNA 3'-trailer cleavage
GE024_RS09845	COG1268	BioY protein
GE024_RS09855	COG0343	queuine tRNA-ribosyltransferase activity
GE024_RS09875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS09875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE024_RS09885	COG4175	Glycine betaine
GE024_RS09885	COG3448	diguanylate cyclase activity
GE024_RS09890	COG1597	lipid kinase activity
GE024_RS09910	COG1070	Carbohydrate kinase
GE024_RS09920	COG3775	system Galactitol-specific IIC component
GE024_RS09925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE024_RS09935	COG1609	Transcriptional regulator
GE024_RS09945	COG3623	hexulose-6-phosphate isomerase
GE024_RS09970	COG0495	leucyl-tRNA aminoacylation
GE024_RS09995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE024_RS10010	COG0564	pseudouridine synthase activity
GE024_RS10025	COG0494	nUDIX hydrolase
GE024_RS10055	COG0542	response to heat
GE024_RS10060	COG4463	regulation of RNA biosynthetic process
GE024_RS10120	COG0346	lactoylglutathione lyase activity
GE024_RS10125	COG0346	lactoylglutathione lyase activity
GE024_RS10130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE024_RS10145	COG0450	alkyl hydroperoxide reductase
GE024_RS10160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GE024_RS10170	COG3404	Formiminotransferase-cyclodeaminase
GE024_RS10185	COG0531	amino acid
GE024_RS10225	COG3590	peptidase
GE024_RS10240	COG0602	queuosine metabolic process
GE024_RS10255	COG1328	CTP reductase activity
GE024_RS10275	COG4472	Bacterial protein of unknown function (DUF965)
GE024_RS10280	COG1393	Belongs to the ArsC family
GE024_RS10300	COG0519	Catalyzes the synthesis of GMP from XMP
GE024_RS10375	COG0488	(ABC) transporter
GE024_RS10380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE024_RS10385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE024_RS10390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE024_RS10440	COG1511	domain protein
GE024_RS10570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GE024_RS10585	COG0305	Participates in initiation and elongation during chromosome replication
GE024_RS10620	COG1760	l-serine dehydratase
GE024_RS10625	COG1760	l-serine dehydratase
GE024_RS10635	COG0741	lytic transglycosylase activity
GE024_RS10655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GE024_RS10665	COG0612	Peptidase, M16
GE024_RS10670	COG0612	Peptidase, M16
GE024_RS10690	COG0488	(ABC) transporter
GE024_RS10695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE024_RS10705	COG0517	IMP dehydrogenase activity
GE024_RS10705	COG0516	GMP reductase activity
GE024_RS10750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE024_RS10755	COG1475	DNA binding